[ { "uniprot_canonical_ac": "Q5F3L7-1", "uniprot_ac": "Q5F3L7", "uniprot_id": "T229B_CHICK", "mass": { "chemical_mass": 19617.0, "monoisotopic_mass": 19617.0 }, "refseq": { "ac": "NP_001384093", "name": "transmembrane protein 229B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093" }, "gene_names": [ { "name": "TMEM229B", "type": "recommended", "evidence": [ { "id": "Q5F3L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7" } ] }, { "name": "C14orf83", "type": "synonym", "evidence": [ { "id": "NP_001384093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093" } ] }, { "name": "RCJMB04_13p15", "type": "synonym", "evidence": [ { "id": "Q5F3L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7" } ] }, { "name": "TMEM229B", "type": "synonym", "evidence": [ { "id": "NP_001384093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093" } ] } ], "protein_names": [ { "name": "Transmembrane protein 229B", "type": "recommended", "evidence": [ { "id": "Q5F3L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 229B", "type": "synonym", "evidence": [ { "id": "NP_001384093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.16519.1, SRR13267656.23007.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482, SAMEA103992648 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Nov 3, 2021 this sequence version replaced XP_015142811.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3L7", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM229B", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7", "locus": { "chromosome": "5", "start_pos": 28261132, "end_pos": 28298179, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020733", "url": "https://www.ensembl.org/id/ENSGALG00010020733" } ] } } ], "crossref": [ { "id": "Q5F3L7", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009493", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423269", "url": "https://www.ncbi.nlm.nih.gov/gene/423269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423269", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423269", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGWSNHR", "url": "https://omabrowser.org/oma/group/DGWSNHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F3L7", "url": "https://www.orthodb.org/?gene=Q5F3L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31746:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31746:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3L7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3L7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001384093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3L7", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3L7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEPLTAFSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVEKMYLYLKDKCHILVRCFIYTLWTYLWEFTTGLILRQFNACPWDYSQFDFDFMGLITLEYAIPWFCASFIMEQLVIRNTLRLRFDETAEPGAPTVPVALANGHVKTD", "length": 167, "header": "sp|Q5F3L7-1|T229B_CHICK Isoform 1 of Transmembrane protein 229B OS=Gallus gallus OX=9031 GN=TMEM229B PE=2 SV=1 CANONICAL=Q5F3L7-1" }, "isoforms": [ { "isoform_ac": "Q5F3L7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7/entry#Q5F3L7-1", "sequence": { "sequence": "MAAAEPLTAFSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVEKMYLYLKDKCHILVRCFIYTLWTYLWEFTTGLILRQFNACPWDYSQFDFDFMGLITLEYAIPWFCASFIMEQLVIRNTLRLRFDETAEPGAPTVPVALANGHVKTD", "length": 167, "header": "sp|Q5F3L7-1|T229B_CHICK Isoform 1 of Transmembrane protein 229B OS=Gallus gallus OX=9031 GN=TMEM229B PE=2 SV=1 CANONICAL=Q5F3L7-1" }, "locus": { "chromosome": "5", "start_pos": 28268134, "end_pos": 28267634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050115.1", "url": "https://www.ensembl.org/id/ENSGALT00010050115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029612.1", "url": "https://www.ensembl.org/id/ENSGALP00010029612.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L7", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423269", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423269", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACC3-1", "protein_name": "Transmembrane protein 229B", "gene_name": "Tmem229b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLVRCVIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPASPPALANGHVKTD", "length": 167 }, "evidence": [ { "id": "Q5F3L7", "url": "https://omabrowser.org/oma/group/Q5F3L7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H1M1-1", "protein_name": "Transmembrane protein 229B", "gene_name": "Tmem229b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLVRCLIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPASPPALANGHVKTD", "length": 167 }, "evidence": [ { "id": "Q5F3L7", "url": "https://omabrowser.org/oma/group/Q5F3L7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5EA70-1", "protein_name": "Transmembrane protein 229B", "gene_name": "TMEM229B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALLVEQFVIRNTLRLRFDKDAEPGEPSGALALANGHVKTD", "length": 167 }, "evidence": [ { "id": "Q5F3L7", "url": "https://omabrowser.org/oma/group/Q5F3L7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BFQ2-1", "protein_name": "Transmembrane protein 229B", "gene_name": "TMEM229B", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLVRCVIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPASPPALANGHVKTD", "length": 167 }, "evidence": [ { "id": "Q5F3L7", "url": "https://omabrowser.org/oma/group/Q5F3L7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBD8-1", "protein_name": "Transmembrane protein 229B", "gene_name": "TMEM229B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNLNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPSGALALANGHVKTD", "length": 167 }, "evidence": [ { "id": "Q5F3L7", "url": "https://omabrowser.org/oma/group/Q5F3L7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5F3L7", "url": "https://www.uniprot.org/uniprotkb/Q5F3L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3L7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 167, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3L7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3L7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F3M0-1", "uniprot_ac": "Q5F3M0", "uniprot_id": "MED24_CHICK", "mass": { "chemical_mass": 110844.0, "monoisotopic_mass": 110844.0 }, "refseq": {}, "gene_names": [ { "name": "MED24", "type": "recommended", "evidence": [ { "id": "Q5F3M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0" } ] }, { "name": "RCJMB04_13m7", "type": "synonym", "evidence": [ { "id": "Q5F3M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 24", "type": "recommended", "evidence": [ { "id": "Q5F3M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 24", "type": "synonym", "evidence": [ { "id": "Q5F3M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F3M0", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3M0", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MED24", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0", "locus": { "chromosome": "27", "start_pos": 4311301, "end_pos": 4327436, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024666", "url": "https://www.ensembl.org/id/ENSGALG00010024666" } ] } } ], "crossref": [ { "id": "Q5F3M0", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3M0", "database": "AlphaFoldDB", "categories": [] }, { "id": "426134", "url": "https://www.ncbi.nlm.nih.gov/gene/426134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426134", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3M0", "url": "https://www.orthodb.org/?gene=Q5F3M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12898", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12898", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12898:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12898:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3M0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3M0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5F3M0", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3M0-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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The reference sequence was derived from JAENSK010000043.1. 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[ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. 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"length": 1057, "header": "sp|Q5F3U0-1|SP130_CHICK Isoform 1 of Histone deacetylase complex subunit SAP130 OS=Gallus gallus OX=9031 GN=SAP130 PE=2 SV=1 CANONICAL=Q5F3U0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3U0", "url": "https://www.uniprot.org/uniprotkb/Q5F3U0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424756", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q5F3U0", "url": "https://www.uniprot.org/uniprotkb/Q5F3U0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5F3U0", "url": "https://www.uniprot.org/uniprotkb/Q5F3U0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "Q5F3U0", "url": "https://www.uniprot.org/uniprotkb/Q5F3U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F3U0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1057, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F3U0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F3U0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] }, { "name": "SCP4", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] }, { "name": "Scp4", "type": "synonym", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] } ], "protein_names": [ { "name": "CTD small phosphatase-like protein 2", "type": "recommended", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] }, { "name": "CTD small phosphatase-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] }, { "name": "CTDSP-like 2", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" }, { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "SCP4", "type": "synonym", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "Small C-terminal domain phosphatase 4", "type": "synonym", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "Small CTD phosphatase 4", "type": "synonym", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#names_and_taxonomy" } ] }, { "name": "small C-terminal domain phosphatase 4", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] }, { "name": "small CTD phosphatase 4", "type": "synonym", "evidence": [ { "id": "NP_001012790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.235980.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000246.1. On or before Oct 7, 2021 this sequence version replaced XP_015147601.1, XP_413942.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001012790", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790" } ] }, { "annotation": "Serine/threonine phosphatase that promotes gluconeogenesis by dephosphorylating FOXO1 and FOXO3A, promoting their nuclear retention and enhancing their transcriptional activity on PCK1 and G6PC1, key enzymes in hepatic gluconeogenesis. May play a role in proper embryonic skeletal development by regulating chondrocyte survival through dephosphorylation of FOXO3. By maintaining FOXO3 in its active, dephosphorylated form, inhibits excessive apoptosis of chondrocytes, which is essential for normal endochondral ossification and cartilage formation.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7#function" }, { "database": "UniProtKB", "id": "Q8BG15", "url": "https://www.uniprot.org/uniprotkb/Q8BG15#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTDSPL2", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7", "locus": { "chromosome": "10", "start_pos": 19796503, "end_pos": 19836797, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016317", "url": "https://www.ensembl.org/id/ENSGALG00010016317" } ] } } ], "crossref": [ { "id": "Q5F3Z7", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415574", "url": "https://www.ncbi.nlm.nih.gov/gene/415574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415574", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3Z7", "url": "https://www.orthodb.org/?gene=Q5F3Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3Z7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3Z7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012790", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012790", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3Z7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLRTRKASQQSNPIHAQRAQRAKRKHSEVEESLPVGGGKPQKNETGLLSSIKKFIKGSTPKEERENPAKRSRIERDIDNNLITSTPQTGEKPNKQISRVRRKGQVNGEAGSYEMTNQHVKQNGKLEDNPATGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTATSTNGAAYTSQAVQVRSTVNNGLEEVEETNDRDLPPLTAPVSPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 466, "header": "sp|Q5F3Z7-1|CTSL2_CHICK Isoform 1 of CTD small phosphatase-like protein 2 OS=Gallus gallus OX=9031 GN=CTDSPL2 PE=2 SV=2 CANONICAL=Q5F3Z7-1" }, "isoforms": [ { "isoform_ac": "Q5F3Z7-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7/entry#Q5F3Z7-1", "sequence": { "sequence": "MRLRTRKASQQSNPIHAQRAQRAKRKHSEVEESLPVGGGKPQKNETGLLSSIKKFIKGSTPKEERENPAKRSRIERDIDNNLITSTPQTGEKPNKQISRVRRKGQVNGEAGSYEMTNQHVKQNGKLEDNPATGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTATSTNGAAYTSQAVQVRSTVNNGLEEVEETNDRDLPPLTAPVSPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 466, "header": "sp|Q5F3Z7-1|CTSL2_CHICK Isoform 1 of CTD small phosphatase-like protein 2 OS=Gallus gallus OX=9031 GN=CTDSPL2 PE=2 SV=2 CANONICAL=Q5F3Z7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:415574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415574", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" }, { "name": "growth plate cartilage chondrocyte growth", "id": "GO:0003430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003430", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z7", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] } ] }, { "uniprot_ac": "A0A8V1AKZ7", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NJB8", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] } ] }, { "uniprot_ac": "F1NXH3", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "P48463", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "Q5F3Z7", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PTJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PTJ6" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": 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"end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F3Z9-1", "uniprot_ac": "Q5F3Z9", "uniprot_id": "ZC3HE_CHICK", "mass": { "chemical_mass": 81653.0, "monoisotopic_mass": 81653.0 }, "refseq": { "ac": "NP_001012604", "name": "zinc finger CCCH domain-containing protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" }, "gene_names": [ { "name": "ZC3H14", "type": "recommended", "evidence": [ { "id": "Q5F3Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ] }, { "name": "2700069A02RIK", "type": "synonym", "evidence": [ { "id": "NP_001012604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" } ] }, { "name": "RCJMB04_4a10", "type": "synonym", "evidence": [ { "id": "Q5F3Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ] }, { "name": "ZC3H14", "type": "synonym", "evidence": [ { "id": "NP_001012604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 14", "type": "recommended", "evidence": [ { "id": "Q5F3Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9/entry#names_and_taxonomy" } ] }, { "name": "nuclear protein UKp68", "type": "synonym", "evidence": [ { "id": "NP_001012604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" } ] }, { "name": "zinc finger CCCH domain-containing protein 14", "type": "synonym", "evidence": [ { "id": "NP_001012604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851501.1, SRR13267659.85680.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Sep 23, 2021 this sequence version replaced NP_001012604.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604" } ] }, { "annotation": "RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Also binds the poly(A) tail of mRNAs; controlling poly(A) length.", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9#function" }, { "database": "UniProtKB", "id": "Q6PJT7", "url": "https://www.uniprot.org/uniprotkb/Q6PJT7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H14", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9", "locus": { "chromosome": "5", "start_pos": 42670767, "end_pos": 42649124, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017996", "url": "https://www.ensembl.org/id/ENSGALG00010017996" } ] } } ], "crossref": [ { "id": "Q5F3Z9", "url": "https://alphafold.ebi.ac.uk/entry/Q5F3Z9", "database": "AlphaFoldDB", "categories": [] }, { "id": "423399", "url": "https://www.ncbi.nlm.nih.gov/gene/423399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423399", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F3Z9", "url": "https://www.orthodb.org/?gene=Q5F3Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14738:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14738:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F3Z9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F3Z9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F3Z9-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIGTEISRKIRGAIKGKLQELGAYVDEELPDYIMVMVANKKSQEQMTEDLSLFLGNNTVRFTVWLHGVLDKLRSVTTEPSGTKSSEPNIFESNHSSSKSSSCVSDERRREDTLPPLAVSSTRSERTDSRVSTSSQEQRNTASRQSCEDGSASRLMSTVKPLRELSPSEAVIDIKPEPDDLIDEDLNFVQENPLSRKKPIVTVTYGSSRPTAEIYRPPASRSADGSLQVHRLPQQGNLQGNRQLDTQSCRSLETVQLCNPEAFGSLAESYRPTSKLSADKVGSEEEGSRKRRLPIVSSVVKVKKFCNDGEEEEEEDDYGLRTGSISSSVSVPAKPERRPSLPPSKQVNKNLILKAISEAQESVTKTTNYSAVPQKQTVPVAPRTRISPEESHLEVIHLQSRLPALCSQLQVEEPKEQAVEGIQGAEQKELSSRLQVDPVIEDTLQVTQDYYDGESMVHTDTRSFILKKPKLSEEIAAQNQQLGKRATEAMRVLSGRLIQTRDQIAQPEKPASPKFIVTLDGVPSPPGYLSDQEEEDMYITEGLKPIPQNICAGKGLKGLRAQQMQIVTRQLDSSDVEMEQLNVLQKQEKVLERCKYWPACKNGDECVYHHPTQPCKVFPNCKFADKCLFIHPNCKYDAKCTKPDCPYTHASRRNPLPSPKPVPLPTQSVSSSSPLCKFFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTIAVPPRHALKWTRTQTSE", "length": 730, "header": "sp|Q5F3Z9-1|ZC3HE_CHICK Isoform 1 of Zinc finger CCCH domain-containing protein 14 OS=Gallus gallus OX=9031 GN=ZC3H14 PE=2 SV=1 CANONICAL=Q5F3Z9-1" }, "isoforms": [ { "isoform_ac": "Q5F3Z9-1", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9/entry#Q5F3Z9-1", "sequence": { "sequence": "MEIGTEISRKIRGAIKGKLQELGAYVDEELPDYIMVMVANKKSQEQMTEDLSLFLGNNTVRFTVWLHGVLDKLRSVTTEPSGTKSSEPNIFESNHSSSKSSSCVSDERRREDTLPPLAVSSTRSERTDSRVSTSSQEQRNTASRQSCEDGSASRLMSTVKPLRELSPSEAVIDIKPEPDDLIDEDLNFVQENPLSRKKPIVTVTYGSSRPTAEIYRPPASRSADGSLQVHRLPQQGNLQGNRQLDTQSCRSLETVQLCNPEAFGSLAESYRPTSKLSADKVGSEEEGSRKRRLPIVSSVVKVKKFCNDGEEEEEEDDYGLRTGSISSSVSVPAKPERRPSLPPSKQVNKNLILKAISEAQESVTKTTNYSAVPQKQTVPVAPRTRISPEESHLEVIHLQSRLPALCSQLQVEEPKEQAVEGIQGAEQKELSSRLQVDPVIEDTLQVTQDYYDGESMVHTDTRSFILKKPKLSEEIAAQNQQLGKRATEAMRVLSGRLIQTRDQIAQPEKPASPKFIVTLDGVPSPPGYLSDQEEEDMYITEGLKPIPQNICAGKGLKGLRAQQMQIVTRQLDSSDVEMEQLNVLQKQEKVLERCKYWPACKNGDECVYHHPTQPCKVFPNCKFADKCLFIHPNCKYDAKCTKPDCPYTHASRRNPLPSPKPVPLPTQSVSSSSPLCKFFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTIAVPPRHALKWTRTQTSE", "length": 730, "header": "sp|Q5F3Z9-1|ZC3HE_CHICK Isoform 1 of Zinc finger CCCH domain-containing protein 14 OS=Gallus gallus OX=9031 GN=ZC3H14 PE=2 SV=1 CANONICAL=Q5F3Z9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423399", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "Q5F3Z9", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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The reference sequence was derived from JAENSK010000065.1. On Mar 10, 2005 this sequence version replaced XP_419929.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001012716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F410", "url": "https://www.uniprot.org/uniprotkb/Q5F410" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM18", "url": "https://www.uniprot.org/uniprotkb/Q5F410", "locus": { "chromosome": "3", "start_pos": 91804479, "end_pos": 91811872, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003844", "url": "https://www.ensembl.org/id/ENSGALG00010003844" } ] } } ], "crossref": [ { "id": "Q5F410", "url": "https://alphafold.ebi.ac.uk/entry/Q5F410", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028744", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028744", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421911", "url": "https://www.ncbi.nlm.nih.gov/gene/421911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421911", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFSKQQY", "url": "https://omabrowser.org/oma/group/TFSKQQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F410", "url": "https://www.orthodb.org/?gene=Q5F410", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22593:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22593:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F410", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F410", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F410", "url": "https://www.uniprot.org/uniprotkb/Q5F410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F410-1", "url": "https://www.uniprot.org/uniprotkb/Q5F410-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSVAVAMEQPLHGPPGLSTILARTDWAEPWLLGLAGFHVLCFLLTCFSFQHYRVQIGHFLCMVCLVYCAEYINELAAMNWRLFSKYQYFDSRGMFISLVFSAPLLVNTIIIVVNWVYRTLNVMTELKTLQQRIKAEKDKKK", "length": 142, "header": "sp|Q5F410-1|TMM18_CHICK Isoform 1 of Transmembrane protein 18 OS=Gallus gallus OX=9031 GN=TMEM18 PE=2 SV=1 CANONICAL=Q5F410-1" }, "isoforms": [ { "isoform_ac": "Q5F410-1", "url": "https://www.uniprot.org/uniprotkb/Q5F410/entry#Q5F410-1", "sequence": { "sequence": "MRSVAVAMEQPLHGPPGLSTILARTDWAEPWLLGLAGFHVLCFLLTCFSFQHYRVQIGHFLCMVCLVYCAEYINELAAMNWRLFSKYQYFDSRGMFISLVFSAPLLVNTIIIVVNWVYRTLNVMTELKTLQQRIKAEKDKKK", "length": 142, "header": "sp|Q5F410-1|TMM18_CHICK Isoform 1 of Transmembrane protein 18 OS=Gallus gallus OX=9031 GN=TMEM18 PE=2 SV=1 CANONICAL=Q5F410-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F410", "url": "https://www.uniprot.org/uniprotkb/Q5F410" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z903-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHPGQIEVNEINGYWTFLLSIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLVLLLAVYFTESINEFAANNWSSFSRQQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKTAQLKERARKERQTKADSESIAHKKAE", "length": 151 }, "evidence": [ { "id": "Q5F410", "url": "https://omabrowser.org/oma/group/Q5F410/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3HBH6-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSPFSVKAFPVSIPAVIMETDWTEPWLLGLVVFHLLCLLLTCFSSQRYKLQIGHFLCLVLLVYFAEYINEVAAMNWRSFSKYQYFDSRGMFISIVFSAPLLFNAMIIVIMWVQKTLNVMSDLKRMQEKRKRRRKEE", "length": 137 }, "evidence": [ { "id": "Q5F410", "url": "https://omabrowser.org/oma/group/Q5F410/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SZ36-1", "protein_name": "Transmembrane protein 18", "gene_name": "TMEM18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSAFSVSRFPVSIPAVITQTDWTEPWLVGLAGFHVLCLLLTCFSSQRYRLQVGHFLCLVTLVYCAEYINEVAAMNWRLFSKHQYFDSRGMFISLVFSAPLLLNALVIVVLWVRKTLVVMTDLRSLREQRRARARPKEE", "length": 139 }, "evidence": [ { "id": "Q5F410", "url": "https://omabrowser.org/oma/group/Q5F410/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TUD9-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSAYSVRSFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE", "length": 140 }, "evidence": [ { "id": "Q5F410", "url": "https://omabrowser.org/oma/group/Q5F410/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q641M3-1", "protein_name": "Transmembrane protein 18", "gene_name": "tmem18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTASNTKNASAIPIDKFSNVRITSIWTFLQSVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLLMVAMVYSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTELKILQLKRKAARENHKKTQ", "length": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F414-1", "uniprot_ac": "Q5F414", "uniprot_id": "PNO1_CHICK", "mass": { "chemical_mass": 26426.0, "monoisotopic_mass": 26426.0 }, "refseq": { "ac": "NP_001072958", "name": "RNA-binding protein PNO1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072958" }, "gene_names": [ { "name": "PNO1", "type": "recommended", "evidence": [ { "id": "Q5F414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ] }, { "name": "PNO1", "type": "synonym", "evidence": [ { "id": "NP_001072958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072958" } ] }, { "name": "RCJMB04_3n12", "type": "synonym", "evidence": [ { "id": "Q5F414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ] } ], "protein_names": [ { "name": "RNA-binding protein PNO1", "type": "recommended", "evidence": [ { "id": "Q5F414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F414/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein PNO1", "type": "synonym", "evidence": [ { "id": "NP_001072958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072958" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851486.1, BU406655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000061.1. On Dec 9, 2006 this sequence version replaced XP_001232273.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001072958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072958" } ] }, { "annotation": "Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414#function" }, { "database": "UniProtKB", "id": "Q9NRX1", "url": "https://www.uniprot.org/uniprotkb/Q9NRX1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PNO1", "url": "https://www.uniprot.org/uniprotkb/Q5F414", "locus": { "chromosome": "3", "start_pos": 11440210, "end_pos": 11436663, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017771", "url": "https://www.ensembl.org/id/ENSGALG00010017771" } ] } } ], "crossref": [ { "id": "Q5F414", "url": "https://alphafold.ebi.ac.uk/entry/Q5F414", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009093", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009093", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769547", "url": "https://www.ncbi.nlm.nih.gov/gene/769547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769547", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPLRNNW", "url": "https://omabrowser.org/oma/group/TPLRNNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F414", "url": "https://www.orthodb.org/?gene=Q5F414", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12826", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12826", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12826:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12826:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F414", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F414", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001072958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F414-1", "url": "https://www.uniprot.org/uniprotkb/Q5F414-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METEAADESGFTSVASKRGRRKRRAAGAEPMEAAESAEAAGPQPSKRPAFPPLPAAALGVGKGEVRKVPVPANRYTPLKENWMKIFTPIVEHLQLQIRFNLKTRNVEIKTCSETKDLSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADSKIHILGSFQNIKMARTAICNLILGSPPSKVYGNIRAVASRAAERF", "length": 242, "header": "sp|Q5F414-1|PNO1_CHICK Isoform 1 of RNA-binding protein PNO1 OS=Gallus gallus OX=9031 GN=PNO1 PE=2 SV=1 CANONICAL=Q5F414-1" }, "isoforms": [ { "isoform_ac": "Q5F414-1", "url": "https://www.uniprot.org/uniprotkb/Q5F414/entry#Q5F414-1", "sequence": { "sequence": "METEAADESGFTSVASKRGRRKRRAAGAEPMEAAESAEAAGPQPSKRPAFPPLPAAALGVGKGEVRKVPVPANRYTPLKENWMKIFTPIVEHLQLQIRFNLKTRNVEIKTCSETKDLSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADSKIHILGSFQNIKMARTAICNLILGSPPSKVYGNIRAVASRAAERF", "length": 242, "header": "sp|Q5F414-1|PNO1_CHICK Isoform 1 of RNA-binding protein PNO1 OS=Gallus gallus OX=9031 GN=PNO1 PE=2 SV=1 CANONICAL=Q5F414-1" }, "locus": { "chromosome": "3", "start_pos": 11439978, "end_pos": 11436751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042942.1", "url": "https://www.ensembl.org/id/ENSGALT00010042942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025432.1", "url": "https://www.ensembl.org/id/ENSGALP00010025432.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:769547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769547", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B6J3-1", "protein_name": "RNA-binding protein PNO1", "gene_name": "PNO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METQMEAQSPLAEDGFTQVTRKGSRRAKKRQAEQLSATEEGGGASHMDTEEARPAKRPIFPPLSGDGFLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALVRLDDLFLETFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRAADRF", "length": 252 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54K66-1", "protein_name": "RNA-binding protein pno1", "gene_name": "pno1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVIETKEVENIISEQSLKTESVKVSNKRSRDDEEMKDSEGGVKKTSFPQISVEDTEEEQIRKVTIPFNRIAPLKANWQQIYEPIVTHLKLQIRMNTKTRKVELKTSKSTKETSALQKAADFVHAFSLGFEVNDAVAILRLDDLYIDSFDVEDVKILKGDNLSRAIGRVAGKDGKTKFTIENVTKTRIVLADKRIHILGSYSNIRVAKDAICDLIIGSPPGKVYAKLRTVSSRIAERF", "length": 239 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6VBQ8-1", "protein_name": "RNA-binding protein PNO1", "gene_name": "Pno1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METQNTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGDAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 248 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7YRD0-1", "protein_name": "RNA-binding protein PNO1", "gene_name": "PNO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESVMEAQSPLAEDGFSQVTRKGGRRAKKRQAEQPSTQEEGGDATCMDTEEARPAKRPVFPPLSGDGFLSGKEETRKIPVPANRYTPLKENWLKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRAADRF", "length": 252 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99216-1", "protein_name": "Pre-rRNA-processing protein PNO1", "gene_name": "PNO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVAPTALKKATVTPVSGQDGGSSRIIGINNTESIDEDDDDDVLLDDSDNNTAKEEVEGEEGSRKTHESKTVVVDDQGKPRFTSASKTQGNKIKFESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNLKTKSVELRTNPKFTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVKTLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY", "length": 274 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9CPS7-1", "protein_name": "RNA-binding protein PNO1", "gene_name": "Pno1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METQSTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGEAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPGNRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVHVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 248 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LTU6-1", "protein_name": "RNA-binding KH domain-containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAESTQMEVETATEGTVPLPPKPTFKPLKAHEMSDGKVQFRKIAVPPNRYSPLKKAWLDIYTPIYDQMKVDIRMNLKARKVELKTRADTPDISNLQKSADFVHAFMLGFDIPDAISLLRMDELYVESFEIKDVKTLKGEHLSRAIGRLSGKGGKTKFAIENSTKTRIVIADTRIHILGAFSNIKVARSSLCSLIMGSPAGKVYSKLRSVSARLNE", "length": 215 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NRX1-1", "protein_name": "RNA-binding protein PNO1", "gene_name": "PNO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESEMETQSARAEEGFTQVTRKGGRRAKKRQAEQLSAAGEGGDAGRMDTEEARPAKRPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 252 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VR89-1", "protein_name": "RNA-binding protein pno1", "gene_name": "l(1)G0004", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAENIRADAFEPAKRATKRGASGGGQQDVEMQVDEATGIEGQVLGSSRASAPPKAKRARSELRKVSVPPHRYSSLKEHWMKIFTPVVEHMKLQIRFNMKARQVELRVGPETPDIANLQRGADFVRAFLCGFEVDDALALLRLEDLFVESFEIKDVKTLRGDHQSRAIGRLAGKGGRTKFTIENVTKTRIVLADSKIHILGSYQNIQLARRAVCNLILGSPPSKVYGNLRAVASRLSERM", "length": 240 }, "evidence": [ { "id": "Q5F414", "url": "https://omabrowser.org/oma/group/Q5F414/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q5F414", "url": "https://www.uniprot.org/uniprotkb/Q5F414" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F414-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 242, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F414-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F414" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"url": "https://www.uniprot.org/uniprotkb/Q5F415" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 23", "type": "recommended", "evidence": [ { "id": "Q5F415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F415/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity). Plays a role in brain development (By similarity). May act as a general inhibitor of innate immunity signaling (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415#function" }, { "database": "UniProtKB", "id": "Q9NUY8", "url": "https://www.uniprot.org/uniprotkb/Q9NUY8#function" }, { "database": "UniProtKB", "id": "Q7SXV1", "url": "https://www.uniprot.org/uniprotkb/Q7SXV1#function" }, { "database": "UniProtKB", "id": "Q8K0F1", "url": "https://www.uniprot.org/uniprotkb/Q8K0F1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D23", "url": "https://www.uniprot.org/uniprotkb/Q5F415", "locus": { "chromosome": "1", "start_pos": 85109304, "end_pos": 85077825, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005590", "url": "https://www.ensembl.org/id/ENSGALG00010005590" } ] } } ], "crossref": [ { "id": "Q5F415", "url": "https://alphafold.ebi.ac.uk/entry/Q5F415", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20788", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20788", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418383", "url": "https://www.ncbi.nlm.nih.gov/gene/418383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418383", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F415", "url": "https://www.orthodb.org/?gene=Q5F415", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13297:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13297:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19430", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19430", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F415", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F415", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F415-1", "url": "https://www.uniprot.org/uniprotkb/Q5F415-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGDGAPPSSWEKDLAEALEEGGCDLETVRNIIQGRQLPADLRAKVWKIALNVVGKGDSLASWDGCLDLPEQSIIHKDCQELIDRLSVPEDEKSVLLLDIESVITFYCKSRNVKYSSCLGWIHLLRPLVHLRLPRSDLYNCFYAIMNKYIPRDCFLKGRPFHLFRLLLQYHEPELCSFLDTKKMTPDSYALNWLGSLFSYYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKDVILAQESEKEEMLKFLETSPANLEVEDIEDLFSLAQYYCSKTPASFRKDNHSLFGSSLLGLKDDDTDLSQALCLAVSVSEILQANQQQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEYVSIARGGFMALQQHLADINVEGPENGYGHWIASTSGSRSSINSSVDGDSPNGSSDGKGVKSLVNKMTVALKTKSVNVKEKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDGIDSSSMSDDDRKEVVNIQTWINKPDVKYNFPCNEVKENGHMFPSHLLVTATNMYCLREIPSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSNTSGIEILAVERYLIPNAGDATKAIKQQIMKVLDALES", "length": 679, "header": "sp|Q5F415-1|TBC23_CHICK Isoform 1 of TBC1 domain family member 23 OS=Gallus gallus OX=9031 GN=TBC1D23 PE=2 SV=1 CANONICAL=Q5F415-1" }, "isoforms": [ { "isoform_ac": "Q5F415-1", "url": "https://www.uniprot.org/uniprotkb/Q5F415/entry#Q5F415-1", "sequence": { "sequence": "MAEGDGAPPSSWEKDLAEALEEGGCDLETVRNIIQGRQLPADLRAKVWKIALNVVGKGDSLASWDGCLDLPEQSIIHKDCQELIDRLSVPEDEKSVLLLDIESVITFYCKSRNVKYSSCLGWIHLLRPLVHLRLPRSDLYNCFYAIMNKYIPRDCFLKGRPFHLFRLLLQYHEPELCSFLDTKKMTPDSYALNWLGSLFSYYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKDVILAQESEKEEMLKFLETSPANLEVEDIEDLFSLAQYYCSKTPASFRKDNHSLFGSSLLGLKDDDTDLSQALCLAVSVSEILQANQQQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEYVSIARGGFMALQQHLADINVEGPENGYGHWIASTSGSRSSINSSVDGDSPNGSSDGKGVKSLVNKMTVALKTKSVNVKEKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDGIDSSSMSDDDRKEVVNIQTWINKPDVKYNFPCNEVKENGHMFPSHLLVTATNMYCLREIPSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSNTSGIEILAVERYLIPNAGDATKAIKQQIMKVLDALES", "length": 679, "header": "sp|Q5F415-1|TBC23_CHICK Isoform 1 of TBC1 domain family member 23 OS=Gallus gallus OX=9031 GN=TBC1D23 PE=2 SV=1 CANONICAL=Q5F415-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418383", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" }, { "name": "embryonic brain development", "id": "GO:1990403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990403", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "Q5F415", "url": "https://www.uniprot.org/uniprotkb/Q5F415" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F415-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 679, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F415-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F415" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F415" }, { "id": "PRU00163", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00163" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000255", "start_pos": 38, "end_pos": 219, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5F415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F415" }, { "id": "PRU00173", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00173" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000255", "start_pos": 327, "end_pos": 439, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 642, "end_pos": 644 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F464-1", "uniprot_ac": "Q5F464", "uniprot_id": "LPP_CHICK", "mass": { "chemical_mass": 65139.0, "monoisotopic_mass": 65139.0 }, "refseq": { "ac": "NP_001026738", "name": "lipoma-preferred partner homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026738" }, "gene_names": [ { "name": "LPP", "type": "recommended", "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ] }, { "name": "LPP", "type": "synonym", "evidence": [ { "id": "NP_001026738", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026738" } ] }, { "name": "RCJMB04_2l20", "type": "synonym", "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ] } ], "protein_names": [ { "name": "Lipoma-preferred partner homolog", "type": "recommended", "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464/entry#names_and_taxonomy" } ] }, { "name": "lipoma-preferred partner homolog", "type": "synonym", "evidence": [ { "id": "NP_001026738", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026738" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851436.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140854 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Aug 8, 2005 this sequence version replaced XP_426703.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026738", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026738" } ] }, { "annotation": "May play a structural role at sites of cell adhesion in maintaining cell shape and motility. May be involved in signal transduction from cell adhesion sites to the nucleus (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LPP", "url": "https://www.uniprot.org/uniprotkb/Q5F464", "locus": { "chromosome": "9", "start_pos": 14039774, "end_pos": 14324623, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014984", "url": "https://www.ensembl.org/id/ENSGALG00010014984" } ] } } ], "crossref": [ { "id": "Q5F464", "url": "https://alphafold.ebi.ac.uk/entry/Q5F464", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007337", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007337", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09356", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09436", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09436", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429148", "url": "https://www.ncbi.nlm.nih.gov/gene/429148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429148", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGMDYTY", "url": "https://omabrowser.org/oma/group/GGMDYTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F464", "url": "https://www.orthodb.org/?gene=Q5F464", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F464", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F464", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026738", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026738", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F464-1", "url": "https://www.uniprot.org/uniprotkb/Q5F464-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDGDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL", "length": 604, "header": "sp|Q5F464-1|LPP_CHICK Isoform 1 of Lipoma-preferred partner homolog OS=Gallus gallus OX=9031 GN=LPP PE=2 SV=1 CANONICAL=Q5F464-1" }, "isoforms": [ { "isoform_ac": "Q5F464-1", "url": "https://www.uniprot.org/uniprotkb/Q5F464/entry#Q5F464-1", "sequence": { "sequence": "MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDGDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL", "length": 604, "header": "sp|Q5F464-1|LPP_CHICK Isoform 1 of Lipoma-preferred partner homolog OS=Gallus gallus OX=9031 GN=LPP PE=2 SV=1 CANONICAL=Q5F464-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 373, "start_aa": "Thr", "end_pos": 373, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr373", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 376, "start_aa": "Thr", "end_pos": 376, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr376", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:429148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1N3M6-1", "protein_name": "LIM domain containing preferred translocation partner in lipoma", "gene_name": "LPP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHPSWLPPKSTAEPLGHVPARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFPPPPPPPLDDSSALPSGSGNFPPPPPLDDGAFRAQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGSTSSATASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMATPSPGQFYGPGPGAQGYNTHTVPMSAQGPPPSARGGMDYAFIPPPGLQPEPGYGYAPNQGRYYEAYCPAGPGYGGKSDSDPAYGQQGHPNAWKREQGYAPSGTVNQNPAGMYPVAGPKKTYITDPVSAPCAPPLQPKGGQTGPLGPPAAPPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 615 }, "evidence": [ { "id": "Q5F464", "url": "https://omabrowser.org/oma/group/Q5F464/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BMD6-1", "protein_name": "LIM domain containing preferred translocation partner in lipoma", "gene_name": "LPP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHPSWLPPKSTAEPLGHVSARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSGSGNFPPPPPLDDNAFRGQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGTTSSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTMKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTPSRPTFNVQVKSAQPSSHYMAAPSPGQFYGSGPGAQGYNTQPVPMSGQGPPPSTRGGMDYAYVPPPGLQPEPGYGYAPNQGRYYEPYCAVGPGYGGKNDSDPSYGQQGHPNTWKREQGYTPSGPGNQNPAGMYPVAGPKKTYITDPVPAPCVPPLQPKGGPAGSMGPPAAPSSFRPEDELEHLTKKMLYDMENPPTDEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 614 }, "evidence": [ { "id": "Q5F464", "url": "https://omabrowser.org/oma/group/Q5F464/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XI07-1", "protein_name": "Lipoma-preferred partner homolog", "gene_name": "Lpp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHPSWLPPRSTGEPLGHVPARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLEDPGTIPSGSGHFPPPPPLDEGAFIVQRGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRAPPGSSSSIASPPVSTPVTGHKRMVIPQQPPLTATKKSATKPQAIPIPVTPIGTLKPQPQPVPASYSTASTSSRPAFNVQVKSAQPSTHYMTGSSSGQMYGPGSRSYNTQQVPLSAQCPPPTTCAGTDYAYIPPSGQQAESGFGYTSNQGRYFEPFFAACPSYGGRNEADPAYGQQVQPNTWKREPGYAAPGAGNQNQPGMYSVSGPKKTYITDPVSAPCAPPVQPKERLVKNQKVLQNVVDDRVHGLRKSGFPAPMGPPSVPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCMVCDIKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKSCNSARIRVLTAKASTDL", "length": 632 }, "evidence": [ { "id": "Q5F464", "url": "https://omabrowser.org/oma/group/Q5F464/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BFW7-1", "protein_name": "Lipoma-preferred partner homolog", "gene_name": "Lpp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKYAPVVAPKPKYNPYKQPGGEGDLLPPPPPPLEDPGTIPPGPGHFPPPPPLDEGAFKVQQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQGSASSIASPPVSTPVTGHKRMVIPQQPPLTATKKSATKPQPAPQAAPIPVTPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAGPSSGQIYGPGPRGYNNQPVPVSGQCPPPPTCVGTDYAYIPPSGHPPESGYGYTSNQGRYYEPYYAAGPSYGGRSEGDTAYGQQVQPNTWKREAAYAPPASGNQNHPGMYPVSGPKKTYITDPVSAPCAPPLQPKGGYPGPMGPPSIPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIVCDVKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 613 }, "evidence": [ { "id": "Q5F464", "url": "https://omabrowser.org/oma/group/Q5F464/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93052-1", "protein_name": "Lipoma-preferred partner", "gene_name": "LPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL", "length": 612 }, "evidence": [ { "id": "Q5F464", "url": "https://omabrowser.org/oma/group/Q5F464/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q5F464", "url": "https://www.uniprot.org/uniprotkb/Q5F464" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F464-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 604, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F464-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F464" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464" }, { "id": "PRU00125", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding 1", "eco_id": "ECO_0000255", "start_pos": 406, "end_pos": 465, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464" }, { "id": "PRU00125", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding 2", "eco_id": "ECO_0000255", "start_pos": 466, "end_pos": 526, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5F464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F464" }, { "id": "PRU00125", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding 3", "eco_id": "ECO_0000255", "start_pos": 527, "end_pos": 595, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 373, 376 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { 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"https://www.ncbi.nlm.nih.gov/gene/424055", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424055", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424055", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F478", "url": "https://www.orthodb.org/?gene=Q5F478", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F478", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F478", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5F478", "url": "https://www.uniprot.org/uniprotkb/Q5F478", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F478-1", "url": "https://www.uniprot.org/uniprotkb/Q5F478-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENVSRSNGPRTSSATDVQKEE", "length": 990, "header": "sp|Q5F478-1|ANR44_CHICK Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B OS=Gallus gallus OX=9031 GN=ANKRD44 PE=2 SV=1 CANONICAL=Q5F478-1" }, "isoforms": [ { "isoform_ac": "Q5F478-1", "url": "https://www.uniprot.org/uniprotkb/Q5F478/entry#Q5F478-1", "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENVSRSNGPRTSSATDVQKEE", "length": 990, "header": "sp|Q5F478-1|ANR44_CHICK Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B OS=Gallus gallus OX=9031 GN=ANKRD44 PE=2 SV=1 CANONICAL=Q5F478-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F478", "url": "https://www.uniprot.org/uniprotkb/Q5F478" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424055", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424055", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F478-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 990, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F478-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F478" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 904, "end_pos": 906 }, { "start_pos": 936, "end_pos": 938 }, { "start_pos": 971, "end_pos": 973 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F479-1", "uniprot_ac": "Q5F479", "uniprot_id": "S11IP_CHICK", "mass": { "chemical_mass": 120233.0, "monoisotopic_mass": 120233.0 }, "refseq": {}, "gene_names": [ { "name": "STK11IP", "type": "recommended", "evidence": [ { "id": "Q5F479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ] }, { "name": "RCJMB04_2g8", "type": "synonym", "evidence": [ { "id": "Q5F479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase 11-interacting protein", "type": "recommended", "evidence": [ { "id": "Q5F479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F479/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STK11IP", "url": "https://www.uniprot.org/uniprotkb/Q5F479", "locus": { "chromosome": "7", "start_pos": 21672256, "end_pos": 21653740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021152", "url": "https://www.ensembl.org/id/ENSGALG00010021152" } ] } } ], "crossref": [ { "id": "Q5F479", "url": "https://alphafold.ebi.ac.uk/entry/Q5F479", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424195", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5F479", "url": "https://www.orthodb.org/?gene=Q5F479", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F479", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F479", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F479-1", "url": "https://www.uniprot.org/uniprotkb/Q5F479-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAEAAAEPLVSGLARLLQDTGDLVLDGSSTLTLLTPTLQHLTRVFEQHLGSRNQHRGFVALPSHPAETTAILQAQFLFDMLQKTHSLKLIHVPNCALQSTVKIFPFKSLRHLELRSVPPHCLRGLRFVYSQLESLTCSKCVSTLEEIISACGGDLSCALPWLELQTVNFSYNSITALDDSLQLLNALRVLDLSHNKVQDCEHYLTTLSELEYLNLAYNFLSKVPNLGIFSQSKLLTLILRNNELDSINGVEQLVNLQHLDVAYNLLLEHAQLAPLSTLHYLKKLHLEGNPLWFHQNHRSATLVHVSPRAASSNFLLDGEPLSSSDLMHLPKLVPSVSQSIHTSTSEKTILDRNALDSSCAADFSDSQSPAENVAVRLPRKKGKGKVKVRRASISEPSDTEHESQALPFSAGLVLQHQKEMERMDSFRDRFGVDWLQYKRLEEHNQVSVICRSRSADETTGRPAAVDLQSESFDPKQVKPRLSPKESSPAFHNAGAEEEPEVQPGEPPGGEQREEEADELMLGEEEDEKPEVDLCQPVLVSQIEGEGDPESDWIFLRVTARHVIEVELKAARVLHKLELKCLQKIETSEMTWKRMDLERVFPVLTLHFTYIRKDRQKRKYVVLDDCPEQCLQCVLEVLSPVVEENWRNQDQEKESLRLQCLKCKHEFLQSLAPWQQGPYPAETGDTKNLETLVALNQDASAAGEPIACPSCSSDHVVILPSEVSSSTPVPPSHDGTSEDLSDSALEGGSQQEGPEEVPALPRESGKFYIGGEDSSEMDTSNSTRTPELSGEHDSTIQSSSHSTDGGYGKKEQGMKSQYLSLSHRDTNGGSLMGSYRYSASRGPTSSQLSMTSDSEETWNLSPSANSALNKRDFRSVDHRLKLYLDMEVFEENDEEFQCFLKVTMVKFGRQGEFLSILVASNLRIYVLEVTGVIRGQPADWLKKDDSHYLSDISHLEVGLCHQSLRMEFENPKASYNLLIRSQSCCDQFLQTLTYLMQELPSKHRSKVKEIPTVEMNPQHWLWPLLDSKNTDSAAAGGTCFFYLLAYLIQEYSAPNWTQFKLRPCCQIDRTN", "length": 1073, "header": "sp|Q5F479-1|S11IP_CHICK Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Gallus gallus OX=9031 GN=STK11IP PE=2 SV=1 CANONICAL=Q5F479-1" }, "isoforms": [ { "isoform_ac": "Q5F479-1", "url": "https://www.uniprot.org/uniprotkb/Q5F479/entry#Q5F479-1", "sequence": { "sequence": "MAAAAEAAAEPLVSGLARLLQDTGDLVLDGSSTLTLLTPTLQHLTRVFEQHLGSRNQHRGFVALPSHPAETTAILQAQFLFDMLQKTHSLKLIHVPNCALQSTVKIFPFKSLRHLELRSVPPHCLRGLRFVYSQLESLTCSKCVSTLEEIISACGGDLSCALPWLELQTVNFSYNSITALDDSLQLLNALRVLDLSHNKVQDCEHYLTTLSELEYLNLAYNFLSKVPNLGIFSQSKLLTLILRNNELDSINGVEQLVNLQHLDVAYNLLLEHAQLAPLSTLHYLKKLHLEGNPLWFHQNHRSATLVHVSPRAASSNFLLDGEPLSSSDLMHLPKLVPSVSQSIHTSTSEKTILDRNALDSSCAADFSDSQSPAENVAVRLPRKKGKGKVKVRRASISEPSDTEHESQALPFSAGLVLQHQKEMERMDSFRDRFGVDWLQYKRLEEHNQVSVICRSRSADETTGRPAAVDLQSESFDPKQVKPRLSPKESSPAFHNAGAEEEPEVQPGEPPGGEQREEEADELMLGEEEDEKPEVDLCQPVLVSQIEGEGDPESDWIFLRVTARHVIEVELKAARVLHKLELKCLQKIETSEMTWKRMDLERVFPVLTLHFTYIRKDRQKRKYVVLDDCPEQCLQCVLEVLSPVVEENWRNQDQEKESLRLQCLKCKHEFLQSLAPWQQGPYPAETGDTKNLETLVALNQDASAAGEPIACPSCSSDHVVILPSEVSSSTPVPPSHDGTSEDLSDSALEGGSQQEGPEEVPALPRESGKFYIGGEDSSEMDTSNSTRTPELSGEHDSTIQSSSHSTDGGYGKKEQGMKSQYLSLSHRDTNGGSLMGSYRYSASRGPTSSQLSMTSDSEETWNLSPSANSALNKRDFRSVDHRLKLYLDMEVFEENDEEFQCFLKVTMVKFGRQGEFLSILVASNLRIYVLEVTGVIRGQPADWLKKDDSHYLSDISHLEVGLCHQSLRMEFENPKASYNLLIRSQSCCDQFLQTLTYLMQELPSKHRSKVKEIPTVEMNPQHWLWPLLDSKNTDSAAAGGTCFFYLLAYLIQEYSAPNWTQFKLRPCCQIDRTN", "length": 1073, "header": "sp|Q5F479-1|S11IP_CHICK Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Gallus gallus OX=9031 GN=STK11IP PE=2 SV=1 CANONICAL=Q5F479-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 846, "start_aa": "Thr", "end_pos": 846, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr846", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424195", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "Q5F479", "url": "https://www.uniprot.org/uniprotkb/Q5F479" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1057, "end_pos": 1059, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5F479-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1073, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5F479-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5F479" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 846 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1057, "end_pos": 1059 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 861, "end_pos": 863 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5F4A9-1", "uniprot_ac": "Q5F4A9", "uniprot_id": "AR6P4_CHICK", "mass": { "chemical_mass": 25758.0, "monoisotopic_mass": 25758.0 }, "refseq": { "ac": "NP_001383543", "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" }, "gene_names": [ { "name": "ARL6IP4", "type": "recommended", "evidence": [ { "id": "Q5F4A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ] }, { "name": "ARL6IP4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] }, { "name": "RCJMB04_1f2", "type": "synonym", "evidence": [ { "id": "Q5F4A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "type": "recommended", "evidence": [ { "id": "Q5F4A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like 6 interacting protein 4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] }, { "name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] }, { "name": "ADP-ribosylation-like factor 6 interacting protein 4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] }, { "name": "ARL-6-interacting protein 4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" }, { "id": "Q5F4A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9/entry#names_and_taxonomy" } ] }, { "name": "Aip-4", "type": "synonym", "evidence": [ { "id": "Q5F4A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9/entry#names_and_taxonomy" } ] }, { "name": "aip-4", "type": "synonym", "evidence": [ { "id": "NP_001383543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.253192.1, SRR13267651.21379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992559 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HAEK01126754.1, AL586145.1, HAEK01002801.1, BU247705.1, AJ741714.1 and AJ741715.1. On or before Oct 26, 2021 this sequence version replaced XP_015131095.2, XP_040540414.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543" } ] }, { "annotation": "May be involved in modulating alternative pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL6IP4", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9", "locus": { "chromosome": "15", "start_pos": 5213332, "end_pos": 5217516, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024893", "url": "https://www.ensembl.org/id/ENSGALG00010024893" } ] } } ], "crossref": [ { "id": "Q5F4A9", "url": "https://alphafold.ebi.ac.uk/entry/Q5F4A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427695", "url": "https://www.ncbi.nlm.nih.gov/gene/427695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WHKSARE", "url": "https://omabrowser.org/oma/group/WHKSARE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5F4A9", "url": "https://www.orthodb.org/?gene=Q5F4A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF10500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5F4A9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5F4A9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001383543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5F4A9-1", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGRSRKRSRSSSRSPSGSGREKGGARSSAASPGPRHRLSSAAAREGRKKEGRKKKKRKAKASSSDRSSSSRSSSSSSSTSSSDSDTRAKQHSRRKRGKHKDKKKKKKMKKKLKKKSKERVKEERGVSEALPGPSLELWQKEPLADSGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRRVVDPETGRTRLIKGDGEVLEEIVSKERHKEINKQATRGDGLAFQVRTGMLK", "length": 231, "header": "sp|Q5F4A9-1|AR6P4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Gallus gallus OX=9031 GN=ARL6IP4 PE=2 SV=1 CANONICAL=Q5F4A9-1" }, "isoforms": [ { "isoform_ac": "Q5F4A9-1", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9/entry#Q5F4A9-1", "sequence": { "sequence": "MARGRSRKRSRSSSRSPSGSGREKGGARSSAASPGPRHRLSSAAAREGRKKEGRKKKKRKAKASSSDRSSSSRSSSSSSSTSSSDSDTRAKQHSRRKRGKHKDKKKKKKMKKKLKKKSKERVKEERGVSEALPGPSLELWQKEPLADSGPVLTDEQKSRIQAMKPMTKEEWDARQSVIRRVVDPETGRTRLIKGDGEVLEEIVSKERHKEINKQATRGDGLAFQVRTGMLK", "length": 231, "header": "sp|Q5F4A9-1|AR6P4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Gallus gallus OX=9031 GN=ARL6IP4 PE=2 SV=1 CANONICAL=Q5F4A9-1" }, "locus": { "chromosome": "15", "start_pos": 5217180, "end_pos": 5214027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060778.1", "url": "https://www.ensembl.org/id/ENSGALT00010060778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037537.1", "url": "https://www.ensembl.org/id/ENSGALP00010037537.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q502P0-1", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "gene_name": "arl6ip4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGSDSDSRSRSRNREENKSRSLSSSSARRPSPNHEKKHEHSSEKKKMKRRRSSSSSSSSSSPSPSREKKAKKKKKRREAKKLKREKKKEKKEKKRQKKLALKAERAAALTASVPAPVPEEKPQTYLKTWQSEETKEHGPAMTDEQKAKLSTRRPLTKEEYEARQSVIRRVLDPETGRTRLIRGDGEILEEIVSKERHKDINKQSTRGDGDAFQKRLGISR", "length": 221 }, "evidence": [ { "id": "Q5F4A9", "url": "https://omabrowser.org/oma/group/Q5F4A9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5F4A9", "url": "https://www.uniprot.org/uniprotkb/Q5F4A9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 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The reference sequence was derived from BK004078.1 and JAENSK010000012.1. On Mar 20, 2015 this sequence version replaced NP_001006229.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001006229", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006229" } ] }, { "annotation": "Transcriptional regulator that acts as a repressor or an activator. 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"uniprot_canonical_ac": "Q5YCC7-1", "uniprot_ac": "Q5YCC7", "uniprot_id": "TMC3_CHICK", "mass": { "chemical_mass": 128763.0, "monoisotopic_mass": 128763.0 }, "refseq": { "ac": "NP_001005820", "name": "transmembrane channel-like protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005820" }, "gene_names": [ { "name": "Tmc3", "type": "recommended", "evidence": [ { "id": "Q5YCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7" } ] }, { "name": "TMC3", "type": "synonym", "evidence": [ { "id": "NP_001005820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005820" } ] } ], "protein_names": [ { "name": "Transmembrane channel-like protein 3", "type": "recommended", "evidence": [ { "id": "Q5YCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane channel-like protein 3", "type": "synonym", "evidence": [ { "id": "NP_001005820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005820" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY581310.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA103992290, SAMEA103992393 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Oct 14, 2021 this sequence version replaced NP_001005820.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001005820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005820" } ] }, { "annotation": "Probable component of an ion channel.", "evidence": [ { "database": "UniProtKB", "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "Tmc3", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7", "locus": {} } ], "crossref": [ { "id": "Q5YCC7", "url": "https://alphafold.ebi.ac.uk/entry/Q5YCC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "415470", "url": "https://www.ncbi.nlm.nih.gov/gene/415470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415470", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5YCC7", "url": "https://www.orthodb.org/?gene=Q5YCC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5YCC7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5YCC7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5YCC7-1", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1138, "header": "sp|Q5YCC7-1|TMC3_CHICK Isoform 1 of Transmembrane channel-like protein 3 OS=Gallus gallus OX=9031 GN=Tmc3 PE=2 SV=1 CANONICAL=Q5YCC7-1" }, "isoforms": [ { "isoform_ac": "Q5YCC7-1", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7/entry#Q5YCC7-1", "sequence": { "sequence": "MEAAPGTAAAAAKPAKSCKKYRMGKRHANIYTYQEPPHSNSDEDISEEKADSQDPEQVFQNIQYQKEVMSNIRCRPWPMRQKLRVLRQAKEIVLKYEGRLTRTRGYQAAGAELWRKFLRLAYNFVVLFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFVVLPELLAGAPFGSTVSKTIRQEDLKTAQDLDTIWSLGGYLQYSVLFYGYYGSDRKIGKAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRMSLASASDENYTFCWRLFCAWDYLIGNPEAAESKAAAIVNSIREAILEEQEKKKSKNLAVTISLRIIANILVLLSLTGSIYIIYFVVDRSQKLENNKRELTLWEKNEVSVVVSLITMIAPSAFELVAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNSMSVTNSIYSIYQVSNNSTPSSATGTPAKEDTLSATISDAQMNSSESHAQSLPTAGSLVNNTASSNSAQNQCWETYVGQEMLKLSIIDMIFTVASILLIDFFRGLCVRYLSDCWCWDLESKFPEYGEFKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAMLLFMLFLCMLPTIFAIARYKPSLSCGPFSGQEKIYDIVSETIQNDFPAWFNSVIAYISSPVVVLPALLLLFMLIYYLQSIARSLKFTNNQLRMKIQAERTEDKKKVVQMAVGQNLVDIPDDQIMSDFTQNSEGTRFQSLDGSDKRPDKDGGLISQESSVRASTPRKNGSVLNFESPVSKGTRIQTISQTVPHAVPSTDVARPVNTTPTTSASLTPAPSVSSAQKPRNDHTTNRYPSVVHGSASELCKTKPYTPVTFKKRIGDVHSEPLFRKSIRQVNPDAFGAGAPVFVGRRPHATRYFIVNENEPRKKSARSTSRLQRQFRIEEPEDIVELYPCNVRRYVVQTPQCMYSPHPSEDEEDEEALGRHYVKRSHRPRSLSDLRPAPRFYIGDRADGHVLTSKVHYKSWDDGFELDLDRPPYAYKKVHLKNVEADQHYLEPQVKPKTKHMLEQSLTESDSVSIESSSDPQNSSNDQYIQVIHSKEKYLKPGTKLTKKKSNTNIELNMSEPNELVCSNV", "length": 1138, "header": "sp|Q5YCC7-1|TMC3_CHICK Isoform 1 of Transmembrane channel-like protein 3 OS=Gallus gallus OX=9031 GN=Tmc3 PE=2 SV=1 CANONICAL=Q5YCC7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 272, "start_aa": "Asn", "end_pos": 272, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn272", "evidence": [ { "id": "Q5YCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 446, "start_aa": "Thr", "end_pos": 446, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr446", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 453, "start_aa": "Thr", "end_pos": 453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr453", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Identification of chicken transmembrane channel-like (TMC) genes: expression analysis in the cochlea.", "journal": "Neuroscience", "date": "2005", "authors": "Mutai H, Mann S, Heller S", "evidence": [ { "database": "UniProtKB", "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7" } ], "reference": [ { "type": "PubMed", "id": "15857715", "url": "https://glygen.org/publication/PubMed/15857715" } ] } ], "pathway": [ { "id": "gga:415470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415470", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "Q5YCC7", "url": "https://www.uniprot.org/uniprotkb/Q5YCC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1091, "end_pos": 1093, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1126, "end_pos": 1128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5/entry#names_and_taxonomy" } ] }, { "name": "homeo box 1B", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] }, { "name": "homeo box A6", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] }, { "name": "homeobox protein HOXA6", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] }, { "name": "homeobox protein Hox-1B", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] }, { "name": "homeobox protein Hox-A6 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] }, { "name": "homeobox protein Hox-A6", "type": "synonym", "evidence": [ { "id": "NP_001026158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU422323.1, AY307380.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000037.1. 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] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420630", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSSPCFY", "url": "https://omabrowser.org/oma/group/YSSPCFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5YLH5", "url": "https://www.orthodb.org/?gene=Q5YLH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5YLH5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5YLH5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5YLH5-1", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSYFVNPTFPGSLPAGQDSFLGQIPLYPAGYDALRHFPTSYGASSLQDKTYTSPCFYQQSNTVIACNRASYEYGASCFYSDKEISSASPSGSGKQRGQGDYLHFSPEQQYKSNGVQSKIVNDEGTDRKYTSPVYPWMQRMNSCAGTVYGAHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKFINSTQPGSDETEEKSGE", "length": 231, "header": "sp|Q5YLH5-1|HXA6_CHICK Isoform 1 of Homeobox protein Hox-A6 OS=Gallus gallus OX=9031 GN=HOXA6 PE=2 SV=1 CANONICAL=Q5YLH5-1" }, "isoforms": [ { "isoform_ac": "Q5YLH5-1", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5/entry#Q5YLH5-1", "sequence": { "sequence": "MSSYFVNPTFPGSLPAGQDSFLGQIPLYPAGYDALRHFPTSYGASSLQDKTYTSPCFYQQSNTVIACNRASYEYGASCFYSDKEISSASPSGSGKQRGQGDYLHFSPEQQYKSNGVQSKIVNDEGTDRKYTSPVYPWMQRMNSCAGTVYGAHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKFINSTQPGSDETEEKSGE", "length": 231, "header": "sp|Q5YLH5-1|HXA6_CHICK Isoform 1 of Homeobox protein Hox-A6 OS=Gallus gallus OX=9031 GN=HOXA6 PE=2 SV=1 CANONICAL=Q5YLH5-1" }, "locus": { "chromosome": "2", "start_pos": 32531886, "end_pos": 32529995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004135.1", "url": "https://www.ensembl.org/id/ENSGALT00010004135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002432.1", "url": "https://www.ensembl.org/id/ENSGALP00010002432.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Analysis of nephric duct specification in the avian embryo.", "journal": "Development (Cambridge, England)", "date": "2012-11", "authors": "Attia Lital, Yelin Ronit, Schultheiss Thomas M", "evidence": [ { "database": "RefSeq", "id": "NP_001026158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026158" } ], "reference": [ { "type": "PubMed", "id": "23034630", "url": "https://glygen.org/publication/PubMed/23034630" } ] } ], "pathway": [ { "id": "gga:420630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420630", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HD76-1", "protein_name": "Homeobox protein Hox-A6", "gene_name": "Hoxa6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSYFVNPTFPGSLPSGQDSFLGQLPLYPAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGNSKQRGPGDYLHFSPEQQYKPDSSSVQGKVLHEEGTDRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE", "length": 233 }, "evidence": [ { "id": "Q5YLH5", "url": "https://omabrowser.org/oma/group/Q5YLH5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P09092-1", "protein_name": "Homeobox protein Hox-A6", "gene_name": "Hoxa6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSYFVNPTFPGSLPSGQDSFLGQLPLYPAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGNNKQRGPGDYLHFSPEQQYKPDGSVQGKALHEEGTDRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQASGEDSEAKAGE", "length": 232 }, "evidence": [ { "id": "Q5YLH5", "url": "https://omabrowser.org/oma/group/Q5YLH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P31267-1", "protein_name": "Homeobox protein Hox-A6", "gene_name": "HOXA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE", "length": 233 }, "evidence": [ { "id": "Q5YLH5", "url": "https://omabrowser.org/oma/group/Q5YLH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5YLH5", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5YLH5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 231, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5YLH5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5YLH5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5YLH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YLH5" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000255", "start_pos": 153, "end_pos": 212, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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The reference sequence was derived from JAENSK010000012.1. 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introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ] }, { "name": "HSPC159", "type": "synonym", "evidence": [ { "id": "NP_001008456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] }, { "name": "LGALSL", "type": "synonym", "evidence": [ { "id": "NP_001008456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] }, { "name": "RCJMB04_34j3", "type": "synonym", "evidence": [ { "id": "Q5ZHQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ] } ], "protein_names": [ { "name": "Galectin-related protein", "type": "recommended", "evidence": [ { "id": "Q5ZHQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2/entry#names_and_taxonomy" } ] }, { "name": "Lectin galactoside-binding-like protein", "type": "synonym", "evidence": [ { "id": "Q5ZHQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2/entry#names_and_taxonomy" } ] }, { "name": "galectin-related protein", "type": "synonym", "evidence": [ { "id": "NP_001008456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] }, { "name": "lectin galactoside-binding-like protein", "type": "synonym", "evidence": [ { "id": "NP_001008456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] }, { "name": "lectin, galactoside-binding-like", "type": "synonym", "evidence": [ { "id": "NP_001008456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721082.1, CR353568.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000061.1. On Dec 16, 2004 this sequence version replaced XP_419347.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456" } ] }, { "annotation": "Does not bind lactose, and may not bind carbohydrates.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LGALSL", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2", "locus": { "chromosome": "3", "start_pos": 9920541, "end_pos": 9913153, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017115", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421278", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CISGEKG", "url": "https://omabrowser.org/oma/group/CISGEKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZHQ2", "url": "https://www.orthodb.org/?gene=Q5ZHQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005it6", "url": "https://www.rcsb.org/structure/pdb_00005it6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5IT6", "url": "https://www.rcsb.org/structure/5IT6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZHQ2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZHQ2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHQ2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGTVAERDAPKIEDGHLNNSLGSPVQADVYFPRLIVPFCGHIKGGMRPGKKILVMGIVDLNPESFGISLTCGESEDPPADVAIELKAVFTDRQFIRNSCVAGEWGEEQSSIPYFPFIPDQPFRVEILCEHPRFRIFVDGHQLFDFYHRIETLSAIDTIKINGDLQLTKLG", "length": 171, "header": "sp|Q5ZHQ2-1|LEGL_CHICK Isoform 1 of Galectin-related protein OS=Gallus gallus OX=9031 GN=LGALSL PE=1 SV=1 CANONICAL=Q5ZHQ2-1" }, "isoforms": [ { "isoform_ac": "Q5ZHQ2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2/entry#Q5ZHQ2-1", "sequence": { "sequence": "MAGTVAERDAPKIEDGHLNNSLGSPVQADVYFPRLIVPFCGHIKGGMRPGKKILVMGIVDLNPESFGISLTCGESEDPPADVAIELKAVFTDRQFIRNSCVAGEWGEEQSSIPYFPFIPDQPFRVEILCEHPRFRIFVDGHQLFDFYHRIETLSAIDTIKINGDLQLTKLG", "length": 171, "header": "sp|Q5ZHQ2-1|LEGL_CHICK Isoform 1 of Galectin-related protein OS=Gallus gallus OX=9031 GN=LGALSL PE=1 SV=1 CANONICAL=Q5ZHQ2-1" }, "locus": { "chromosome": "3", "start_pos": 9916967, "end_pos": 9913177, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041302.1", "url": "https://www.ensembl.org/id/ENSGALT00010041302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024187.1", "url": "https://www.ensembl.org/id/ENSGALP00010024187.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421278", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B4F7A3-1", "protein_name": "Galectin", "gene_name": "Lgalsl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYSSASLGPSVLLLLQTVKLTFLPLGWNSLKEAIPGLPLLLPPPSQDLAPDPPQQSQDAEGATALPGLQPWSNGRRAGHAEQAAVPGPRPRPVPGPRFPSRALPPLNATPGRRTAALATVIPSPPRPPRRTPPLPLPGLRPRQPGACARAGVCARPARTRARRRVPGARCRNMAGSVADSDAVVKLDDGHLNNSLGSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG", "length": 344 }, "evidence": [ { "id": "Q5ZHQ2", "url": "https://omabrowser.org/oma/group/Q5ZHQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L8J2-1", "protein_name": "Galectin", "gene_name": "LGALSL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSVADSDAVVKLDDGHLNNSLGSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG", "length": 172 }, "evidence": [ { "id": "Q5ZHQ2", "url": "https://omabrowser.org/oma/group/Q5ZHQ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZCW2-1", "protein_name": "Galectin-related protein", "gene_name": "LGALSL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG", "length": 172 }, "evidence": [ { "id": "Q5ZHQ2", "url": "https://omabrowser.org/oma/group/Q5ZHQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VED9-1", "protein_name": "Galectin-related protein", "gene_name": "Lgalsl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSVADSDAVVKLDDGHLNNSLGSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG", "length": 172 }, "evidence": [ { "id": "Q5ZHQ2", "url": "https://omabrowser.org/oma/group/Q5ZHQ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHQ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZHQ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 171, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZHQ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZHQ2" }, { "pdb_id": "5it6", "pdb_chain": "a", "start_pos": 38, "end_pos": 171, "overlap": "1.0", "method": "X-Ray_Crystallography", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/5it6.pdb", "url_external": "https://www.rcsb.org/structure/5it6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZHQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHQ2" }, { "id": "PRU00639", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00639" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galectin", "eco_id": "ECO_0000255", "start_pos": 38, "end_pos": 170, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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16379.0 }, "refseq": { "ac": "NP_001026207", "name": "nuclear nucleic acid-binding protein C1D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207" }, "gene_names": [ { "name": "C1D", "type": "recommended", "evidence": [ { "id": "Q5ZHS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ] }, { "name": "C1D", "type": "synonym", "evidence": [ { "id": "NP_001026207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207" } ] }, { "name": "RCJMB04_33m12", "type": "synonym", "evidence": [ { "id": "Q5ZHS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ] } ], "protein_names": [ { "name": "Nuclear nucleic acid-binding protein C1D", "type": "recommended", "evidence": [ { "id": "Q5ZHS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3/entry#names_and_taxonomy" } ] }, { "name": "C1D nuclear receptor co-repressor", "type": "synonym", "evidence": [ { "id": "NP_001026207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207" } ] }, { "name": "nuclear nucleic acid-binding protein C1D", "type": "synonym", "evidence": [ { "id": "NP_001026207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721061.1, CN229305.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ453246.1, CV889988.1, DR419424.1 and AJ721061.1. On Sep 28, 2011 this sequence version replaced NP_001026207.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001026207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207" } ] }, { "annotation": "Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3#function" }, { "database": "UniProtKB", "id": "Q13901", "url": "https://www.uniprot.org/uniprotkb/Q13901#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1D", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3", "locus": { "chromosome": "3", "start_pos": 11402228, "end_pos": 11419676, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017755", "url": "https://www.ensembl.org/id/ENSGALG00010017755" } ] } } ], "crossref": [ { "id": "Q5ZHS3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZHS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "421267", "url": "https://www.ncbi.nlm.nih.gov/gene/421267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421267", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZHS3", "url": "https://www.orthodb.org/?gene=Q5ZHS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15341:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15341:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZHS3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZHS3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHS3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDINAEEYPTEIHDYLTTFEKSLTSVDEMLKTMMSVSRSELLQKLEPLEQAKLDLVSAYTLNSMFWVYLATQGINPKEHPVKQELERIRTYMNKVKEIADKKKASKLDKGAASRFVRNALWEPNPENGQTPAKAKKRKMN", "length": 142, "header": "sp|Q5ZHS3-1|C1D_CHICK Isoform 1 of Nuclear nucleic acid-binding protein C1D OS=Gallus gallus OX=9031 GN=C1D PE=2 SV=1 CANONICAL=Q5ZHS3-1" }, "isoforms": [ { "isoform_ac": "Q5ZHS3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3/entry#Q5ZHS3-1", "sequence": { "sequence": "MAEDINAEEYPTEIHDYLTTFEKSLTSVDEMLKTMMSVSRSELLQKLEPLEQAKLDLVSAYTLNSMFWVYLATQGINPKEHPVKQELERIRTYMNKVKEIADKKKASKLDKGAASRFVRNALWEPNPENGQTPAKAKKRKMN", "length": 142, "header": "sp|Q5ZHS3-1|C1D_CHICK Isoform 1 of Nuclear nucleic acid-binding protein C1D OS=Gallus gallus OX=9031 GN=C1D PE=2 SV=1 CANONICAL=Q5ZHS3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421267", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" }, { "name": "exosome (RNase complex)", "id": "GO:0000178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000178", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHS3", "url": "https://www.uniprot.org/uniprotkb/Q5ZHS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZHS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 142, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZHS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZHS3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZHV2-1", "uniprot_ac": "Q5ZHV2", "uniprot_id": "NAA35_CHICK", "mass": { "chemical_mass": 83539.0, "monoisotopic_mass": 83539.0 }, "refseq": {}, "gene_names": [ { "name": "NAA35", "type": "recommended", "evidence": [ { "id": "Q5ZHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ] }, { "name": "MAK10", "type": "synonym", "evidence": [ { "id": "Q5ZHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ] }, { "name": "RCJMB04_32o21", "type": "synonym", "evidence": [ { "id": "Q5ZHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "type": "recommended", "evidence": [ { "id": "Q5ZHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2/entry#names_and_taxonomy" } ] }, { "name": "Protein MAK10 homolog", "type": "synonym", "evidence": [ { "id": "Q5ZHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues (By similarity). N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2#function" }, { "database": "UniProtKB", "id": "Q5VZE5", "url": "https://www.uniprot.org/uniprotkb/Q5VZE5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAA35", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2", "locus": { "chromosome": "Z", "start_pos": 41369045, "end_pos": 41342044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008699", "url": "https://www.ensembl.org/id/ENSGALG00010008699" } ] } } ], "crossref": [ { "id": "Q5ZHV2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZHV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q5ZHV2", "url": "https://www.orthodb.org/?gene=Q5ZHV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21373:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21373:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHV2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMKASVEDDDSGWELGMPDKMEKSNTDWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTSPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQELMTQAADLLSAIHNSCIHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSKLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDYIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHSMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADSSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMYKTMIAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVITPPPVHYLQFKEMSDLNKYSPPPQSADLYMAASKHFQQAKMILENIPNPDHEVNRILKVAKPNIVVMKLLAGGHKKDSKVPPEFDFSPHKYFPVVKLV", "length": 725, "header": "sp|Q5ZHV2-1|NAA35_CHICK Isoform 1 of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA35 PE=2 SV=1 CANONICAL=Q5ZHV2-1" }, "isoforms": [ { "isoform_ac": "Q5ZHV2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2/entry#Q5ZHV2-1", "sequence": { "sequence": "MVMKASVEDDDSGWELGMPDKMEKSNTDWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTSPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQELMTQAADLLSAIHNSCIHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSKLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDYIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHSMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADSSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMYKTMIAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVITPPPVHYLQFKEMSDLNKYSPPPQSADLYMAASKHFQQAKMILENIPNPDHEVNRILKVAKPNIVVMKLLAGGHKKDSKVPPEFDFSPHKYFPVVKLV", "length": 725, "header": "sp|Q5ZHV2-1|NAA35_CHICK Isoform 1 of N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA35 PE=2 SV=1 CANONICAL=Q5ZHV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "pmid": "" }, { "name": "NatC complex", "id": "GO:0031417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031417", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "pmid": "" }, { "name": "smooth muscle cell proliferation", "id": "GO:0048659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048659", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZHV2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 725, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZHV2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZHV2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZHV8-1", "uniprot_ac": "Q5ZHV8", "uniprot_id": "RMI1_CHICK", "mass": { "chemical_mass": 69236.0, "monoisotopic_mass": 69236.0 }, "refseq": { "ac": "NP_001026783", "name": "recQ-mediated genome instability protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783" }, "gene_names": [ { "name": "RMI1", "type": "recommended", "evidence": [ { "id": "Q5ZHV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ] }, { "name": "RCJMB04_32l8", "type": "synonym", "evidence": [ { "id": "Q5ZHV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ] }, { "name": "RMI1", "type": "synonym", "evidence": [ { "id": "NP_001026783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783" } ] } ], "protein_names": [ { "name": "RecQ-mediated genome instability protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZHV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8/entry#names_and_taxonomy" } ] }, { "name": "RMI1, RecQ mediated genome instability 1, homolog", "type": "synonym", "evidence": [ { "id": "NP_001026783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783" } ] }, { "name": "recQ-mediated genome instability protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721026.1, AJ453015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ721026.1. On Aug 8, 2005 this sequence version replaced XP_429222.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783" } ] }, { "annotation": "Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RMI1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8", "locus": { "chromosome": "Z", "start_pos": 40707695, "end_pos": 40702151, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014737", "url": "https://www.ensembl.org/id/ENSGALG00010014737" } ] } } ], "crossref": [ { "id": "Q5ZHV8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZHV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "431669", "url": "https://www.ncbi.nlm.nih.gov/gene/431669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431669", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZHV8", "url": "https://www.orthodb.org/?gene=Q5ZHV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14790", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14790", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14790:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14790:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZHV8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZHV8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026783", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZHV8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTPNVTARVETWLSSTWHVKVPLTWLEACINWIQEENGGGNLSQAQISRQVFEQWLLTDLRDLEYPILPDGILDAPKGELSGFYSLQIDSLLDVSQPAYSQLQKIRGKSTVNEEVTANTQAFQKPWEAKPTRMLMLQLTDGIHQIQGMEYQPVPVLHSNLPPGTKITVHGNVAYRLGVLLLKPENVKLLGGEVDALLEEYSQERVLARLLGEAENPDSVRQPGHEQIVPGPVDELGQTLGPSDEELLASLDENNDFILNNETSLESGYCSRSNNFSATSCSLTTYNENTTGFPLQQESVNLLPRSDEQTPPSVEYNDAFLNDFPLEDDILLEEEIQRELEEVPSVARNGNVNLSTERIPHTYRSSCGSSLNETSEKDDGCGSEKPVEVTSKQKNLARTVSTGDGTSTGGSLQCNSVSQACSSAIVLLKNPHEERRNDLGPDESSCQSRHAPDSRQLNKDPVSSSKTDPEADQQAILCRPGNACDLDLDSPPFTYISLLLAKKPETITLVKVKCFIVTLTGNLTSSNGSWGIKAKVSDGSAYLEVDFADDILTSLIGFSVPEMHTLRKDPALQPKLKDGLERCQKQLIDLCCLMTIEFNPFQSKATVLILQDTDARHLEQLKKRLNK", "length": 627, "header": "sp|Q5ZHV8-1|RMI1_CHICK Isoform 1 of RecQ-mediated genome instability protein 1 OS=Gallus gallus OX=9031 GN=RMI1 PE=2 SV=1 CANONICAL=Q5ZHV8-1" }, "isoforms": [ { "isoform_ac": "Q5ZHV8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8/entry#Q5ZHV8-1", "sequence": { "sequence": "MSTPNVTARVETWLSSTWHVKVPLTWLEACINWIQEENGGGNLSQAQISRQVFEQWLLTDLRDLEYPILPDGILDAPKGELSGFYSLQIDSLLDVSQPAYSQLQKIRGKSTVNEEVTANTQAFQKPWEAKPTRMLMLQLTDGIHQIQGMEYQPVPVLHSNLPPGTKITVHGNVAYRLGVLLLKPENVKLLGGEVDALLEEYSQERVLARLLGEAENPDSVRQPGHEQIVPGPVDELGQTLGPSDEELLASLDENNDFILNNETSLESGYCSRSNNFSATSCSLTTYNENTTGFPLQQESVNLLPRSDEQTPPSVEYNDAFLNDFPLEDDILLEEEIQRELEEVPSVARNGNVNLSTERIPHTYRSSCGSSLNETSEKDDGCGSEKPVEVTSKQKNLARTVSTGDGTSTGGSLQCNSVSQACSSAIVLLKNPHEERRNDLGPDESSCQSRHAPDSRQLNKDPVSSSKTDPEADQQAILCRPGNACDLDLDSPPFTYISLLLAKKPETITLVKVKCFIVTLTGNLTSSNGSWGIKAKVSDGSAYLEVDFADDILTSLIGFSVPEMHTLRKDPALQPKLKDGLERCQKQLIDLCCLMTIEFNPFQSKATVLILQDTDARHLEQLKKRLNK", "length": 627, "header": "sp|Q5ZHV8-1|RMI1_CHICK Isoform 1 of RecQ-mediated genome instability protein 1 OS=Gallus gallus OX=9031 GN=RMI1 PE=2 SV=1 CANONICAL=Q5ZHV8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:431669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431669", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" }, { "name": "RecQ family helicase-topoisomerase III complex", "id": "GO:0031422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031422", "evidence": [ { "database": "UniProtKB", "id": "Q5ZHV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZHV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, 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The reference sequence was derived from JAENSK010000316.1. 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"categories": [ "Protein" ] }, { "id": "Q5ZI11", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI11-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEFRRAYAKLCAAPQEAVLRRLRERGEAPGRARLDLAEQSLSLETCGALGRLLPGAAHFAEVALGDCGLSEDGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSLRK", "length": 670, "header": "sp|Q5ZI11-1|LRC45_CHICK Isoform 1 of Leucine-rich repeat-containing protein 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=2 SV=1 CANONICAL=Q5ZI11-1" }, "isoforms": [ { "isoform_ac": "Q5ZI11-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11/entry#Q5ZI11-1", "sequence": { "sequence": "MEEFRRAYAKLCAAPQEAVLRRLRERGEAPGRARLDLAEQSLSLETCGALGRLLPGAAHFAEVALGDCGLSEDGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSLRK", "length": 670, "header": "sp|Q5ZI11-1|LRC45_CHICK Isoform 1 of Leucine-rich repeat-containing protein 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=2 SV=1 CANONICAL=Q5ZI11-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI11", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:770573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770573", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI11", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI11", "url": "https://www.uniprot.org/uniprotkb/Q5ZI11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 670, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI11" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, 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to final NCBI review. The reference sequence was derived from JAENSK010000074.1. On Sep 23, 2021 this sequence version replaced NP_001026339.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM129", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25", "locus": { "chromosome": "4", "start_pos": 83424712, "end_pos": 83417308, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016592", "url": "https://www.ensembl.org/id/ENSGALG00010016592" } ] } } ], "crossref": [ { "id": "Q5ZI25", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI25", "database": "AlphaFoldDB", "categories": [] }, { "id": "422900", "url": "https://www.ncbi.nlm.nih.gov/gene/422900", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422900", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422900", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZI25", "url": "https://www.orthodb.org/?gene=Q5ZI25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31322:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31322:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10272", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10272", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI25", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI25", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI25-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPAVTFTLAYLVFAVCFVFPPDEVRSAGLTVQSLLAAWLGSEDAAFVQYHLRRSTGTLLAHSLLPLGYYFGMCFAAPEKHLCFFYLASKEWKTFFFFAVLLPAVSSTMAYYWSRKGWNNHPLARTLAVYALPQSGWRAVASSINTEFRRIDKFATGAPGARVIVTDTWVIKVTTYCLHVAQQQDIHLTVTDSRQHELTPDSNMPVQFLTIRVASVNPYVKAFDIRLNSAEYGELREKLRAPISNAANVVIHQSLSDLFLETFTSLVEMNQTYSVPSTQELEPCIGCMQTIANIKLIKNCQEPNEGECQQCYCRPMWCLTCMGKWFASRQDQQHPETWLSSHVPCPTCRAKFCILDVCIIR", "length": 362, "header": "sp|Q5ZI25-1|TM129_CHICK Isoform 1 of Transmembrane protein 129 OS=Gallus gallus OX=9031 GN=TMEM129 PE=2 SV=1 CANONICAL=Q5ZI25-1" }, "isoforms": [ { "isoform_ac": "Q5ZI25-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25/entry#Q5ZI25-1", "sequence": { "sequence": "MESPAVTFTLAYLVFAVCFVFPPDEVRSAGLTVQSLLAAWLGSEDAAFVQYHLRRSTGTLLAHSLLPLGYYFGMCFAAPEKHLCFFYLASKEWKTFFFFAVLLPAVSSTMAYYWSRKGWNNHPLARTLAVYALPQSGWRAVASSINTEFRRIDKFATGAPGARVIVTDTWVIKVTTYCLHVAQQQDIHLTVTDSRQHELTPDSNMPVQFLTIRVASVNPYVKAFDIRLNSAEYGELREKLRAPISNAANVVIHQSLSDLFLETFTSLVEMNQTYSVPSTQELEPCIGCMQTIANIKLIKNCQEPNEGECQQCYCRPMWCLTCMGKWFASRQDQQHPETWLSSHVPCPTCRAKFCILDVCIIR", "length": 362, "header": "sp|Q5ZI25-1|TM129_CHICK Isoform 1 of Transmembrane protein 129 OS=Gallus gallus OX=9031 GN=TMEM129 PE=2 SV=1 CANONICAL=Q5ZI25-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422900", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422900", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI25", "url": "https://www.uniprot.org/uniprotkb/Q5ZI25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 362, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI25" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZI27-1", "uniprot_ac": "Q5ZI27", "uniprot_id": "NAIF1_CHICK", "mass": { "chemical_mass": 36195.0, "monoisotopic_mass": 36195.0 }, "refseq": {}, "gene_names": [ { "name": "NAIF1", "type": "recommended", "evidence": [ { "id": "Q5ZI27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ] }, { "name": "RCJMB04_31b24", "type": "synonym", "evidence": [ { "id": "Q5ZI27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ] } ], "protein_names": [ { "name": "Nuclear apoptosis-inducing factor 1", "type": "recommended", "evidence": [ { "id": "Q5ZI27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Induces apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAIF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27", "locus": { "chromosome": "17", "start_pos": 5499907, "end_pos": 5495685, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028061", "url": "https://www.ensembl.org/id/ENSGALG00010028061" } ] } } ], "crossref": [ { "id": "Q5ZI27", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI27", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI27", "url": "https://www.orthodb.org/?gene=Q5ZI27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35449:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35449:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI27", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI27", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI27-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPPAPPAKKRKMNFSEREVEIIVEELERGKHLLINHFNAGVPLAAKAAAWHDILRRVNAVATCHRELPEVKKKWSDLKTEVRRKVAQVRAAMEGGGESQNGGGAGTEGEDPTGATAAPVILTPMQQRICNLLGEATIISLPSGDCGAGRRDRDPHHRLRHHRHADPGVSAAPSEVPAETTYHSLEDGVVEYCTTEAPTTVTAEAPLEMMAHQHEVSAKPQELKSRIALNSAKLLQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSALIQVLRPMIKDFRRFLQSNTPSPSVTADPNQTGQQDGIIQ", "length": 330, "header": "sp|Q5ZI27-1|NAIF1_CHICK Isoform 1 of Nuclear apoptosis-inducing factor 1 OS=Gallus gallus OX=9031 GN=NAIF1 PE=2 SV=1 CANONICAL=Q5ZI27-1" }, "isoforms": [ { "isoform_ac": "Q5ZI27-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27/entry#Q5ZI27-1", "sequence": { "sequence": "MASPPAPPAKKRKMNFSEREVEIIVEELERGKHLLINHFNAGVPLAAKAAAWHDILRRVNAVATCHRELPEVKKKWSDLKTEVRRKVAQVRAAMEGGGESQNGGGAGTEGEDPTGATAAPVILTPMQQRICNLLGEATIISLPSGDCGAGRRDRDPHHRLRHHRHADPGVSAAPSEVPAETTYHSLEDGVVEYCTTEAPTTVTAEAPLEMMAHQHEVSAKPQELKSRIALNSAKLLQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSALIQVLRPMIKDFRRFLQSNTPSPSVTADPNQTGQQDGIIQ", "length": 330, "header": "sp|Q5ZI27-1|NAIF1_CHICK Isoform 1 of Nuclear apoptosis-inducing factor 1 OS=Gallus gallus OX=9031 GN=NAIF1 PE=2 SV=1 CANONICAL=Q5ZI27-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "central element", "id": "GO:0000801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000801", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break processing involved in reciprocal meiotic recombination", "id": "GO:0010705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010705", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane permeability involved in apoptotic process", "id": "GO:1902108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902108", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI27", "url": "https://www.uniprot.org/uniprotkb/Q5ZI27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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final NCBI review. The reference sequence was derived from JAENSK010000036.1. On Sep 23, 2021 this sequence version replaced NP_001012875.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012875" } ] }, { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI33", "url": "https://www.uniprot.org/uniprotkb/Q5ZI33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI33-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGSEKSSKKKTEKKLAAREEAKLLAGFMGVMNSMRKQRTLCDVILMVQERRIPAHRVVLASASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPYMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVEGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSRRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKMNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586, "header": "sp|Q5ZI33-1|KLHL7_CHICK Isoform 1 of Kelch-like 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZI40-1", "uniprot_ac": "Q5ZI40", "uniprot_id": "QTMAN_CHICK", "mass": { "chemical_mass": 43822.0, "monoisotopic_mass": 43822.0 }, "refseq": {}, "gene_names": [ { "name": "QTMAN", "type": "recommended", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ] }, { "name": "GTDC1", "type": "synonym", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ] }, { "name": "RCJMB04_30i19", "type": "synonym", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ] } ], "protein_names": [ { "name": "tRNA-queuosine alpha-mannosyltransferase", "type": "recommended", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.110", "type": "synonym", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40/entry#names_and_taxonomy" } ] }, { "name": "Glycosyltransferase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40/entry#names_and_taxonomy" } ] }, { "name": "QTMAN", "type": "synonym", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40#function" }, { "database": "UniProtKB", "id": "Q4AE62", "url": "https://www.uniprot.org/uniprotkb/Q4AE62#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "QTMAN", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40", "locus": {} } ], "crossref": [ { "id": "Q5ZI40", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI40", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR022701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424304", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424304", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZI40", "url": "https://www.orthodb.org/?gene=Q5ZI40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI40", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI40", "database": "PRO", "categories": [ "Protein" ] }, { "id": "12885", "url": "https://www.rhea-db.org/rhea/12885", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI40-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLLIEAFYGGSHKQLMDLLQEELKEECVLCTLPAKKWHWKARTAALYFMQTVPASANYRILFASSVLNLAELAALRPDLGKLKKVLYFHENQLAYPVQKCKERDFQCGYNQVLSCLVADTVVFNSAFNMESFLTSIGKFMKLIPDHRPKDLEKIIRPKCQVLYFPVRFPDVSRFMPEHKLAHLENVIGVKRNGDFYQREGLPGQQKSRALGGLMKNSNACRESGLCETQPGLCTTQHEGLHSPLTAAGRLNKSEASESTNPCQEEDKQHVTFNLCNIWSGMDYLQRPLHVVWPHRWEHDKDPETFFKVLLKLKEQELPFHVSVLGETFTDVPGWKRCIVAVTRCVPRPWCTRRSSQLNICILHLNSFLKGFRISARDQIL", "length": 382, "header": "sp|Q5ZI40-1|QTMAN_CHICK Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Gallus gallus OX=9031 GN=QTMAN PE=2 SV=1 CANONICAL=Q5ZI40-1" }, "isoforms": [ { "isoform_ac": "Q5ZI40-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40/entry#Q5ZI40-1", "sequence": { "sequence": "MSVLLIEAFYGGSHKQLMDLLQEELKEECVLCTLPAKKWHWKARTAALYFMQTVPASANYRILFASSVLNLAELAALRPDLGKLKKVLYFHENQLAYPVQKCKERDFQCGYNQVLSCLVADTVVFNSAFNMESFLTSIGKFMKLIPDHRPKDLEKIIRPKCQVLYFPVRFPDVSRFMPEHKLAHLENVIGVKRNGDFYQREGLPGQQKSRALGGLMKNSNACRESGLCETQPGLCTTQHEGLHSPLTAAGRLNKSEASESTNPCQEEDKQHVTFNLCNIWSGMDYLQRPLHVVWPHRWEHDKDPETFFKVLLKLKEQELPFHVSVLGETFTDVPGWKRCIVAVTRCVPRPWCTRRSSQLNICILHLNSFLKGFRISARDQIL", "length": 382, "header": "sp|Q5ZI40-1|QTMAN_CHICK Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Gallus gallus OX=9031 GN=QTMAN PE=2 SV=1 CANONICAL=Q5ZI40-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424304", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tRNA-queuosine(34) beta-mannosyltransferase activity", "id": "GO:0016438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016438", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI40", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12885", "name": "", "equation": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZI40-1", "A0A8V0Y209-1" ], "evidence": [ { "id": "12885", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12885" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y209", "gene_name": "GTDC1", "activity": [ { "ec_number": "2.4.1.110", "activity": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+).", "evidence": [ { "id": "A0A8V0Y209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y209" } ] }, { "ec_number": "2.4.1.110", "activity": "", "evidence": [ { "id": "A0A8V0Y209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y209" } ] } ] }, { "uniprot_ac": "Q5ZI40", "gene_name": "QTMAN", "activity": [ { "ec_number": "2.4.1.110", "activity": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+).", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ] }, { "ec_number": "2.4.1.110", "activity": "", "evidence": [ { "id": "Q5ZI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI40" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI40-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 382, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI40-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI40" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.110", "ec_name": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+).", "evidence": [ { "id": "2.4.1.110", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.110" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZI57-1", "uniprot_ac": "Q5ZI57", "uniprot_id": "TPPC3_CHICK", "mass": { "chemical_mass": 20276.0, "monoisotopic_mass": 20276.0 }, "refseq": { "ac": "NP_001008451", "name": "trafficking protein particle complex subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008451" }, "gene_names": [ { "name": "TRAPPC3", "type": "recommended", "evidence": [ { "id": "Q5ZI57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ] }, { "name": "RCJMB04_30c23", "type": "synonym", "evidence": [ { "id": "Q5ZI57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ] }, { "name": "TRAPPC3", "type": "synonym", "evidence": [ { "id": "NP_001008451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008451" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 3", "type": "recommended", "evidence": [ { "id": "Q5ZI57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57/entry#names_and_taxonomy" } ] }, { "name": "trafficking protein particle complex subunit 3", "type": "synonym", "evidence": [ { "id": "NP_001008451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008451" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720927.1, HAEK01001307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000339.1. On Dec 16, 2004 this sequence version replaced XP_417772.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008451" } ] }, { "annotation": "May play a role in vesicular transport from endoplasmic reticulum to Golgi.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC3", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57", "locus": { "chromosome": "23", "start_pos": 4466316, "end_pos": 4451959, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014859", "url": "https://www.ensembl.org/id/ENSGALG00010014859" } ] } } ], "crossref": [ { "id": "Q5ZI57", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI57", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002284", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002284", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14942", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14942", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419625", "url": "https://www.ncbi.nlm.nih.gov/gene/419625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419625", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZI57", "url": "https://www.orthodb.org/?gene=Q5ZI57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI57", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI57", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI57-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQAGRGTESKKMNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 180, "header": "sp|Q5ZI57-1|TPPC3_CHICK Isoform 1 of Trafficking protein particle complex subunit 3 OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=2 SV=1 CANONICAL=Q5ZI57-1" }, "isoforms": [ { "isoform_ac": "Q5ZI57-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57/entry#Q5ZI57-1", "sequence": { "sequence": "MSRQAGRGTESKKMNSELFTLTYGALVTQLCKDYENDEDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKIAFKMYLGITPSITNWSPGGDEFSLILENNPLVDFVELPDNHSSLIYSNLLCGVLRGALEMVQMAVDVKFVQDTLKGDSVTEIRMKFIRRIEDNLPAGEE", "length": 180, "header": "sp|Q5ZI57-1|TPPC3_CHICK Isoform 1 of Trafficking protein particle complex subunit 3 OS=Gallus gallus OX=9031 GN=TRAPPC3 PE=2 SV=1 CANONICAL=Q5ZI57-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419625", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI57", "url": "https://www.uniprot.org/uniprotkb/Q5ZI57" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI57-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 180, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI57-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI57" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 79607.0, "monoisotopic_mass": 79607.0 }, "refseq": { "ac": "NP_001006504", "name": "NHL repeat-containing protein 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006504" }, "gene_names": [ { "name": "NHLRC2", "type": "recommended", "evidence": [ { "id": "Q5ZI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67" } ] }, { "name": "NHLRC2", "type": "synonym", "evidence": [ { "id": "NP_001006504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006504" } ] }, { "name": "RCJMB04_29n5", "type": "synonym", "evidence": [ { "id": "Q5ZI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67" } ] } ], "protein_names": [ { "name": "NHL repeat-containing protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67/entry#names_and_taxonomy" } ] }, { "name": "NHL repeat-containing protein 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001006504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006504" } ] }, { "name": "NHL repeat-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006504" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Nov 5, 2021 this sequence version replaced NP_001006504.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006504", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006504" } ] }, { "annotation": "Required for normal embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI67", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67#function" }, { "database": "UniProtKB", "id": "Q8BZW8", "url": "https://www.uniprot.org/uniprotkb/Q8BZW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI67", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NHLRC2", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67", "locus": { "chromosome": "6", "start_pos": 28394416, "end_pos": 28356602, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022400", "url": "https://www.ensembl.org/id/ENSGALG00010022400" } ] } } ], "crossref": [ { "id": "Q5ZI67", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI67", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423903", "url": "https://www.ncbi.nlm.nih.gov/gene/423903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423903", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZI67", "url": "https://www.orthodb.org/?gene=Q5ZI67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46388", "url": 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI67", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI67-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLVYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGRLTQVELTHSFITN", "length": 727, "header": "sp|Q5ZI67-1|NHLC2_CHICK Isoform 1 of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=2 SV=1 CANONICAL=Q5ZI67-1" }, "isoforms": [ { "isoform_ac": "Q5ZI67-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI67/entry#Q5ZI67-1", "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLVYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGRLTQVELTHSFITN", "length": 727, "header": "sp|Q5ZI67-1|NHLC2_CHICK Isoform 1 of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=2 SV=1 CANONICAL=Q5ZI67-1" }, "locus": {} } ], 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein D-like", "type": "recommended", "evidence": [ { "id": "Q5ZI72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein D-like", "type": "synonym", "evidence": [ { "id": "NP_001026313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" } ] }, { "name": "hnRNP D-like", "type": "synonym", "evidence": [ { "id": "NP_001026313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" }, { "id": "Q5ZI72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72/entry#names_and_taxonomy" } ] }, { "name": "hnRNP DL", "type": "synonym", "evidence": [ { "id": "Q5ZI72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72/entry#names_and_taxonomy" } ] }, { "name": "hnRNP-DL", "type": "synonym", "evidence": [ { "id": "NP_001026313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" } ] }, { "name": "hnRPD-like protein", "type": "synonym", "evidence": [ { "id": "NP_001026313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720912.1, HAEK01090920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Aug 8, 2005 this sequence version replaced XP_420560.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313" } ] }, { "annotation": "Acts as a transcriptional regulator. Binds DNA and RNA (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HNRNPDL", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72", "locus": { "chromosome": "4", "start_pos": 45986297, "end_pos": 45981962, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004003", "url": "https://www.ensembl.org/id/ENSGALG00010004003" } ] } } ], "crossref": [ { "id": "Q5ZI72", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023199", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023199", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422601", "url": "https://www.ncbi.nlm.nih.gov/gene/422601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422601", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422601", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVDTEMN", "url": "https://omabrowser.org/oma/group/QVDTEMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI72", "url": "https://www.orthodb.org/?gene=Q5ZI72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI72", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI72", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI72-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDATEMSGGAEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVEKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGKSNASGGRGGGRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYSDQSYSGYGGYDYSGYNYPNYGYGPGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "length": 301, "header": "sp|Q5ZI72-1|HNRDL_CHICK Isoform 1 of Heterogeneous nuclear ribonucleoprotein D-like OS=Gallus gallus OX=9031 GN=HNRNPDL PE=2 SV=1 CANONICAL=Q5ZI72-1" }, "isoforms": [ { "isoform_ac": "Q5ZI72-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72/entry#Q5ZI72-1", "sequence": { "sequence": "MEDATEMSGGAEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVEKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGKSNASGGRGGGRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYSDQSYSGYGGYDYSGYNYPNYGYGPGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "length": 301, "header": "sp|Q5ZI72-1|HNRDL_CHICK Isoform 1 of Heterogeneous nuclear ribonucleoprotein D-like OS=Gallus gallus OX=9031 GN=HNRNPDL PE=2 SV=1 CANONICAL=Q5ZI72-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422601", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYE7-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVPPRLSQVPPPLFPSAPATLASRSLSHWRPRAPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGVAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARPHPPADNPAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1N2T0-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O14979-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08473-1", "protein_name": "RNA-binding protein squid", "gene_name": "sqd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAENKQVDTEINGEDFTKDVTADGPGSENGDAGAAGSTNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQRHQPY", "length": 344 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3SWU3-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "Hnrnpdl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGTARSALPLPQSPARALRPSGAARAAPSLSPSRFSACPLDPSSFPTSGNKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGDESYSGYGGYDYTGYNYGSYGYGQGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "length": 322 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q75K16-1", "protein_name": "RNA-binding region RNP-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAKDQKAIESKKRKKEESESETESSEENNASSSSESESEDELKVVGEGSSSSKSTFTKKESAAKDESSNTKTDDDLKVFVGQLPSGVTEYDLKEYFSECGDISNIKILNSNPQRVAAFITFADEKGRDTAITYNGKDFNGQGSLRINGANSKPSDGEGEPTTIVCRNIAFTVDETLVKEFFSKCGSISRVSLPVYEDSGRLKGFAFVSFDSEDAVEKAIALTGTKFEGREIQVERSQRGGGRSSSFGRGGGRGGFGGGRGGRGGFGNGGGRGGFGGGRGGGRGGSGGRGGFGNKRGRFE", "length": 299 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LHL2-1", "protein_name": "RNA-binding (RRM/RBD/RNP motifs) family protein", "gene_name": "RBGD3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSRSRNDNFQSGDGASPGKIFIGGLHKDTTNTVFNKHFGKYGEITDSVIMRDRHTGQPRGFGFITFADPSVVDKVIEDTHVINGKQVEIKRTIPKGAGGNQSKDIKTKKIFVGGIPSTVTEDELKDFFAKYGNVVEHQVIRDHETNRSRGFGFVIFDSEEVVDELLSKGNMIDMADTQVEIKKAEPKKSLNRSPPSYGSHPRGRSSNDSYASYGGPYGGFDGGYGHPPGPIRSHGGPASRYAGGYGYGRGSVGPEFGGGYNNYGGGSLGGYRNEPPLGYSSRFGPYGSGFGGEGYGRGGEGAYLGYPRGGGEGYGGYGGPGYGGAYESGGPGGSYEGAGGPYGRGYSSSSRYHPYAR", "length": 358 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z130-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "Hnrnpdl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 301 }, "evidence": [ { "id": "Q5ZI72", "url": "https://omabrowser.org/oma/group/Q5ZI72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI72", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 301, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI72" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZI72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" }, { "id": "PRU00176", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00176" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM 1", "eco_id": "ECO_0000255", "start_pos": 30, "end_pos": 112, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZI72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI72" }, { "id": "PRU00176", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00176" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM 2", "eco_id": "ECO_0000255", "start_pos": 115, "end_pos": 194, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZI89-1", "uniprot_ac": "Q5ZI89", "uniprot_id": "TPC11_CHICK", "mass": { "chemical_mass": 128551.0, "monoisotopic_mass": 128551.0 }, "refseq": { "ac": "NP_001026707", "name": "trafficking protein particle complex subunit 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" }, "gene_names": [ { "name": "TRAPPC11", "type": "recommended", "evidence": [ { "id": "Q5ZI89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ] }, { "name": "C4H4ORF41", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "C4orf41", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "FOIGR", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "GRY", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "LGMD2S", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "RCJMB04_29e4", "type": "synonym", "evidence": [ { "id": "Q5ZI89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ] }, { "name": "TRAPPC11", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 11", "type": "recommended", "evidence": [ { "id": "Q5ZI89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89/entry#names_and_taxonomy" } ] }, { "name": "UPF0636 protein C4orf41", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "foie gras homolog", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "gryzun homolog", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "name": "trafficking protein particle complex subunit 11", "type": "synonym", "evidence": [ { "id": "NP_001026707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720895.1, SRR13267661.19013.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Aug 8, 2005 this sequence version replaced XP_426304.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707" } ] }, { "annotation": "Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC11", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89", "locus": { "chromosome": "4", "start_pos": 39325128, "end_pos": 39350434, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007294", "url": "https://www.ensembl.org/id/ENSGALG00010007294" } ] } } ], "crossref": [ { "id": "Q5ZI89", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZI89", "database": "AlphaFoldDB", "categories": [] }, { "id": "428748", "url": "https://www.ncbi.nlm.nih.gov/gene/428748", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428748", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428748", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVEYYRD", "url": "https://omabrowser.org/oma/group/CVEYYRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZI89", "url": "https://www.orthodb.org/?gene=Q5ZI89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14374:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14374:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZI89", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZI89", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZI89-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPSQWDLPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNMLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLASMLCNHDSSVVYPNPDPLETQTGVLDFYGQRPWRQGTLSFDLSDPEKEKMGILSLQLKERNVLHSELIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYFAKDYAKALKLLDYVMCEYRSEGWWTLLTSILTTALKCSYLMAQIKDYITYSLELLGRASTLKDDQKSRIEKNLIKVLMNESPDPEPDCDAAAVKASQKLWSDRVSLAGSNVFTIEVQDFIPFVQCKAKFLAPSFHVDVPVQFDIYLRADCPHPIRFSKLCISFNNQDYNQYCVVEEAYQKSDILEQSSQGTMCLVPGKTRKFTFKFVAKTEDVGKKIEITSVDLILGSESGRCVILNWRGGGGDAASSQEALQAARSFRRRPKLPDNEVHWDSLAIQASTMIISRVPNISVQLRHEPPALTNEMYCLVVTIESHEETVAKDVKLTAGLKPGQDANLTQKTQVTLRGTDTCDDSFPALLPDIPVGDLQPGEKLEKPIYIRCGTVGARMFLVYVSYLINTTVEGKEILCKCHRDETVTIETVFPFDVAIKFVSTKLEHLDRVFADIPFLLMTDILSASPWPLTIVTSQLQLSASMTSVDQLESYVENVVLQTGESASECFCLRCPPVTNSGGVATGCYIISWKRSSPVESVPVVSTVITLPHVIVESIPLHVKADLPSFGRVRESLPVRYHLQNKTNLVQDVEVSMEPSDAFMFSGLKQIRLRILPGTQQEVLYNFYPLMAGYQQLPSLHINLLRFPNFTNQLLRRFIPTHIFVKPQGRQADENSIAAA", "length": 1132, "header": "sp|Q5ZI89-1|TPC11_CHICK Isoform 1 of Trafficking protein particle complex subunit 11 OS=Gallus gallus OX=9031 GN=TRAPPC11 PE=2 SV=1 CANONICAL=Q5ZI89-1" }, "isoforms": [ { "isoform_ac": "Q5ZI89-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89/entry#Q5ZI89-1", "sequence": { "sequence": "MTPSQWDLPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNMLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLASMLCNHDSSVVYPNPDPLETQTGVLDFYGQRPWRQGTLSFDLSDPEKEKMGILSLQLKERNVLHSELIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYFAKDYAKALKLLDYVMCEYRSEGWWTLLTSILTTALKCSYLMAQIKDYITYSLELLGRASTLKDDQKSRIEKNLIKVLMNESPDPEPDCDAAAVKASQKLWSDRVSLAGSNVFTIEVQDFIPFVQCKAKFLAPSFHVDVPVQFDIYLRADCPHPIRFSKLCISFNNQDYNQYCVVEEAYQKSDILEQSSQGTMCLVPGKTRKFTFKFVAKTEDVGKKIEITSVDLILGSESGRCVILNWRGGGGDAASSQEALQAARSFRRRPKLPDNEVHWDSLAIQASTMIISRVPNISVQLRHEPPALTNEMYCLVVTIESHEETVAKDVKLTAGLKPGQDANLTQKTQVTLRGTDTCDDSFPALLPDIPVGDLQPGEKLEKPIYIRCGTVGARMFLVYVSYLINTTVEGKEILCKCHRDETVTIETVFPFDVAIKFVSTKLEHLDRVFADIPFLLMTDILSASPWPLTIVTSQLQLSASMTSVDQLESYVENVVLQTGESASECFCLRCPPVTNSGGVATGCYIISWKRSSPVESVPVVSTVITLPHVIVESIPLHVKADLPSFGRVRESLPVRYHLQNKTNLVQDVEVSMEPSDAFMFSGLKQIRLRILPGTQQEVLYNFYPLMAGYQQLPSLHINLLRFPNFTNQLLRRFIPTHIFVKPQGRQADENSIAAA", "length": 1132, "header": "sp|Q5ZI89-1|TPC11_CHICK Isoform 1 of Trafficking protein particle complex subunit 11 OS=Gallus gallus OX=9031 GN=TRAPPC11 PE=2 SV=1 CANONICAL=Q5ZI89-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428748", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428748", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1K5-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "Trappc11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDIIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVVYPSPDPLETPTGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEMIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLMNVLMNESPDPEPDCDALAVKTAQKLWADRVSLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCVSFNNQGYNQFCVLEEASKASEVLENLTQGKMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKRRPKLPDDEVHWDSIIVQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSQEKSQIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLNPGEQLEKTVYVRCGTVGSRMFLVYVSYLINTTVEGKGIMCKCHKDETVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMTDILSASPWALTIVSSELQLAPSMAAMDHLESQIDKVVLQTGESASECFCLRCPSAGNLEGGVATGHYIISWKRSSGMENIPAISTIITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "length": 1133 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3L7IJD9-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "Trappc11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDIIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKVGSAELSFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHARALCNHDASVMYPSPDPLETQTGVLDFYGQRPWRQGVLSFDLSDPEKEKAGVLAIQLLERSVVHSEIIISLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLMNVLMNESPDPEPDCDVLAVKTAQKLWADRVSLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCVSFNNQAYNQFCVLEEASKASEVLENLTQGKMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLVLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKRRPKLPNNEVHWDSIIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSQIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLHPGEQLEKTVYVRCGTVGSRMFLVYVSYLINTTVEGKEIVCKCHKDETVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMTDVLSASPWALTIVSSELQLAPSMTTMDHLESQVDKVVLQTGESASECFCLRCPSAGNVEGGVATGHYIISWKRTSSMENIPVISTVITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPSFTNQLLRRFLPTSIFVKPQGRLLDDASIAAA", "length": 1133 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RXC1-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "Trappc11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGVLKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRIAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMAKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVMYPNPDPLETQSGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEIIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDEQKSRIEKNLMNVLMNESPDPEPDCDVLAVKTAQKLWADRVSLAGSNVFQIGVQDFVPFVQCKAKFHAPSFHVDVPVEFDVFLKADCPHPIRFSKLCVSFNNQVYNQFCVLEEASKASEVLENLTQGKMCLVPGKTRKLSFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKRRPKLAEDEIHWDSVIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLHPGEQLEKTVYVRCGTVGSRMFLVYVSYLINTTVEGKEIICKCHKDDTVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMTDVLSASPWALTIVSSELQLAPSMTAMDHLESQIDKVVLQTGESASECFCLRCPSAGNIEGGVATGHYIISWKRASVVESIPAVSTVITLPHVIAENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "length": 1133 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MXL8-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "TRAPPC11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRPKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLAKALCNHEASVTYPNPDPLETQAGVLDFYGQRSWRQGVLSFDLSDPEKEKVGILAIQLKERSVVHSEVIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLINVLMNESPDPEPDCDILAVKTAQKLWVDRISLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCISFNNQEYNQFCVIEEASKASDVLENLTQGKMCLVPGKTRKFLFKFVAKTEDVGKKIEITSVDLVLGSEAGRCVVLNWQGGGGDAASTQEALQASRSFKRRPRLPDSEVHWDGIVIQASTMIISRVPNISVHLRHDPPALTNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGTELCDESYPALLTDIPVGDLQPGEQLEKAVYVRCGTVGSRMFLVYVSYLINTAIEGKETVCKCHKDETVTIETVFPFDVAVKFVSTKFEHLERVYADIPFLLMTDLLSASPWALTIVSSELQLAPSMTPVDQLESQVDRVVLQTGESASECFCLRCPSVGNVEGGVATGHYVISWKRTSATDGVPVISTVITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTEQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLVDDASIAAA", "length": 1133 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4JXM9-1", "protein_name": "Trafficking protein particle complex subunit-like protein", "gene_name": "ROG2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEYPEELRTPPVSLVALFGYAELHASITKYLHSQQPPINALAFPDFSQISLLLAHDDQISRTSSFRDPLSVSDSASPIPSRCGGILKRDWLLKHRTKVPALVAAFFPSHHIFGDPTQWLQVCSDLDSLKSVIRPKNIKLVVVVVQSSPHEDISDDRLVALRKRAELDSKYVLFFNSSIVSELTLSLSRLASAFAELALSYYREEGRRIKSRIEKRSSNSLDLNVRYCFKVAVYAEFRRDWGEALKFYEDAYHSLHEMIGTSTRLPAIQRLVEIKIIAEQLHFKISTLLLHGGKLIEAVTWFHQHKTSYEKVVGSTEFIFLHWDWMSRQFLVFAELLETSSATGQSLTSSNQGTAEISLTEFEFYPAYYYQLAAHYLKDKKSALELLLSMSEIAQEIDSSSASITPSVYVGQFAQLLEKGEAITLHSITDEEYTRYTISEAKRVQDSLQIIAWLKRSYESFTNLKAQRMAALCAFEVAREYFDLADPNNAKFFFDIAANLYRQEGWVTLLWEVLGYLRECSRNLDALKDFVEFSLEMVALPVTSYENSGNLRNKNYGPGGPATISGRESIHQEVFTLVCREAELLSSTEGSGFKLATDSPLHLEIDLVSPLRPVLLASVAFHDQMIKPHALCSFTLSLLSHLPLPVEIDHLEVQFNQSTCNFVIRNSQRPLWASASNTVKSGSQVENAPLLVLVPNNWLRLTYAIKSEQSGKLECLSVLAKLGPLFTICSRAESPAAMEDLPVWKHENRVESLPTKDPVLAVFGQKATQVDEPEPQVDVSLGASGPALVGEDFAMPIVVTSKGHAVYSGELKINLVDVGGGGLFSPREAEPFSLESHHVEICGIDGAEGNNESESETGSIKKIQQSFGLVSVPYLKEGESWSCKLEIKWHRPKPVMLFVSLGYLPHGSEANTQKVHIHKSLQIEGKMPLLISNRFMLPYRRDHLLLNRIKPAPDSEDVSSLPLNEKSVLVVSAKNCSEIALKLVSMSIEFDDEQGETSCLIQQGGGCGDSPSSANLAPGEEFKKVFTVIPTTRTPKLGLGSIHLKWRREGGNITEAYVSTKHKLPEVNVEASPLVMSLDSPPYAILGEPFTYAVRICNQTQLLQEAKFGLADAQSFVLSGSHSNTVSVLPKSEHVLSYKLVPLTCGEQQLPKITLTSARYAAEFQPSAVASSVFVFPSAPQAEKAISTSK", "length": 1190 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1RLX4-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "trappc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPARWDLPPELCCRPMAFVALTGLDVVYNAIHRAIWDAFCANRRADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVLFYELDWDDPQWKEKQSECATKVEIVRTSLQGRNTKVAVVLIQKKTPLPPGEDLVASERASALCGACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYNEIRRVKSHKEFLNKTTHQLLFVRHQFKMGFFSELKQDTQNALKYYRTAYSLVHELRAHETNVLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHTAWMSKQFQSFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQQAGQLCSHEPGVGYPAPDPLETTSGALDFYGQRPWRQGHQSIDPPDSEKEKQGILALQVKERDVLHSELIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYHAKDYTKALKLLDYVMCDYRTERWWSLLTSIVCTALKCSYLMGQVKDYITYSMELVGRASILSEEQKSRIEKNLIKVLMNEVPEPEPDCDPVSVKAAQSLWSDRVSLAGNNEFTIDVQDYVPFVQCKAKFLSPSFHIDEPVQLHVYVRADCPHPVRFSKLCVSLSNQEYNQYCLLEDAYKGKDILEPSSQENMCLVPGKTRKYCFNFVAKTEDVGKKIEITSVGLMLGRETGRYVYLNWRGGWGDAASSHESLQASRSFKRRTRLPEQHVDWDAVSVQSSTMIISRVPKISVQLTHEPPALTNEMFCMTVTIKSEEDTVGKDIKLTAGLKPGQDANLTQSTQITLNGSEVCDDSHPALLPDIPLGDLQPGQKIVKPLYIRCVSTGSRIFLFHVAYSVSATVEGKDITCKCHKDETVTVETVVPFEVAMKFVSSKFEHLERVYVDIPFLLMMDILSASPWPIELVESEVQLASSMTAIDQPQSQVEGVTLQTSECASECFLLKCPPVQNGTSTVASGHYIISWKRKSTFTETSVVRTVITLPHVMVENIPLYVHAEVPSFGRVRESLPVRYHLENRTGLVQDVEISVEPSDAFMFSGLKQVRMRILPGAEQEMLYNFYPLMAGYQVLPQLNINLLRFPNISSQLLRRFLPSRIFVKPQGRNGDASIEAA", "length": 1132 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54KR2-1", "protein_name": "DUF1683 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNELPDDLVLSPQPLIGLIGCQSLHSQIIDCLSTKNVTDFERIHPTTPSNNNTPILTSTIGGDNRRNSGQYSSSPSIDPFSILHNNNNNNTSNYSNSPSSLSNQLGELSLQQKSLSQFDELWKSPTQKVGTPILTSAATGGEAGGWRFQNSNIPLFKTVPLETDSLSFKKEKKVEVNPHPMGILKANWIHKHTFSIPSVVSLFLQWPDDKNNSKAHDQMLQQVDLVRTNMKSRNIKLIVIIVTSIVLDHEEKVNTIRKKADIDPKYFLFLNKQDIKPFVKKWERLALELSEQYYKEMCQYTKSQIAKSNHPFLSIRYNFKIAFYSEFFRGDNSTSLKYYRDCYNLLNYKSNNDSRGIRFAEIRSLASFFNFKICKISMLNSDIATTTTTPTNTTPNTPNSITTNPSISITPSIPILATTTLTTSTPGGTILSPTGTPGMMQQPSSQQQQQAQFSTSPLQSQYQPSYLQQQSLQPSQPQQQIQQSGTGFFYQQQQQSQQSQQSQQQILLQQQQNQFEKQIKLIQDSLNQFEKHIKTFKIYMGPAEKEFTHCIWLAREYQIFAELLELCPSIIRSNFNTNPGFYYQISAKHQGNRRDSFKALSNHYKENVNVLEYRDIKPKFDLSNLTYIGQPPPVGSHPLDDNNNNNNNTNNTNNISNNNNTQLQTYEEQLTIADENDLSKSIAIELSLNYTNLIIKTLVKAYDQSTVSGNHRILSFIESLIAYEYFISKQYDLALKYYNKNAFTYRREKWTTLLTHSLSMLLKSVHYLNLPTNYIGYALDYLSPELNNTVADRANIQNTIIHILTDGAQKLSPPLSLEKSLDINMDHVHPLLDCRVQFPSSFTFTNSTTEFYVVIGSHFPNPIRFSALKVIFSEKSYNKSIHDKQPIQSPINQSTIKRDDHSRQDLIFLPDESRLFTFKLEVAKEKMELECLSVILELGNIGSPTKTINFVWNVQEWAIKSDETEIEKKIKDPSSLLISTTTTPPIQNKLKDKNIKTTQQQQQQQPPKTLEKLNPYKKFLERSSIRILDHESLIQIKCNHSSPAIVNEFYEIELEIINNDAEIKGGTIRFEIQQSQQTTTLLQQNPQQPLPQTQHSHHHHQQQQQQQQQQLQQQQLQQQQQQQQLQQQQQSVNIININNQSCEKGIYLEPNRSTPLSEMKLTTIKETKSFKKMFYVYSSVVDENKLLISISYETKTGEISHTSKLFTIPVVVGFNTQFQFFNEHLQLITDLYDQGVQTRENLLLLSEIKSQLPFNIIIENTKLSISTAAESARNATLLSPNVANNNPNTPNNNPNNNNPNNNPNNPNNNSGGVNNNIINNLNMILDDSINNLPVAQLLSDSNKLLKDVELSKNTTYSGWFNLIPLVISESISFGSFIIEWRRKGQSSKIISTLPIQLPYIRTTPNPFLAKVHVPSFGIVGQPLTQSIIIKNNTNFLQEFDLQVINPPSYGNSDIPFFFSGDKQSTFSIHPDSTHEIKHILLPLVAGKLNLPHFKIISKRFNKELSKTKNTNNFIFVKPNLNWNQ", "length": 1524 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z392-1", "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "TRAPPC11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRPKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHDAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLAKTLCNHEASVMYPNPDPLETQTGVLDFYGQRSWRQGILSFDLSDPEKEKVGILAIQLKERNVVHSEIIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSVLTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLINVLMNESPDPEPDCDILAVKTAQKLWADRISLAGSNIFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDIYLKADCPHPIRFSKLCVSFNNQEYNQFCVIEEASKANEVLENLTQGKMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLALGNETGRCVVLNWQGGGGDAASSQEALQAARSFKRRPKLPDNEVHWDSIIIQASTMIISRVPNISVHLLHEPPALTNEMYCLVVTVQSHEKTQIRDVKLTAGLKPGQDANLTQKTHVTLHGTELCDESYPALLTDIPVGDLHPGEQLEKMLYVRCGTVGSRMFLVYVSYLINTTVEEKEIVCKCHKDETVTIETVFPFDVAVKFVSTKFEHLERVYADIPFLLMTDLLSASPWALTIVSSELQLAPSMTTVDQLESQVDNVILQTGESASECFCLQCPSLGNIEGGVATGHYIISWKRTSAMENIPIITTVITLPHVIVENIPLHVNADLPSFGRVRESLPVKYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTEQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLMDDTSIAAA", "length": 1133 }, "evidence": [ { "id": "Q5ZI89", "url": "https://omabrowser.org/oma/group/Q5ZI89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q5ZI89", "url": "https://www.uniprot.org/uniprotkb/Q5ZI89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZI89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1132, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZI89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZI89" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 800, "end_pos": 802 }, { "start_pos": 862, "end_pos": 864 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIC8-1", "uniprot_ac": "Q5ZIC8", "uniprot_id": "IPO13_CHICK", "mass": { "chemical_mass": 107776.0, "monoisotopic_mass": 107776.0 }, "refseq": {}, "gene_names": [ { "name": "IPO13", "type": "recommended", "evidence": [ { "id": "Q5ZIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ] }, { "name": "RCJMB04_27p9", "type": "synonym", "evidence": [ { "id": "Q5ZIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ] } ], "protein_names": [ { "name": "Importin-13", "type": "recommended", "evidence": [ { "id": "Q5ZIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8/entry#names_and_taxonomy" } ] }, { "name": "Imp13", "type": "synonym", "evidence": [ { "id": "Q5ZIC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPO13", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8", "locus": { "chromosome": "8", "start_pos": 20051684, "end_pos": 20016600, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021353", "url": "https://www.ensembl.org/id/ENSGALG00010021353" } ] } } ], "crossref": [ { "id": "Q5ZIC8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424573", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIC8", "url": "https://www.orthodb.org/?gene=Q5ZIC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12363:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12363:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIC8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIC8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIC8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRAEAPPPPQGLDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWLLLNMDKVPEIQYSAPAPCTSRSPATGTTSLPDQYESLKSQLFTHITRFAGGSKIVLTRLCVALASLALSMMPEAWPCAVADMVRMFQAEDSNVDGRARCLALLELLTVLPEEFQTSRLPQYRKGQVRSVLAQECGSVFPLLEQLLQQQDSPGFIKQKVLKCFSSWVQLEIPLMDCENLIQAAFTSLQDPELFDTAVEAVVNAISQPDAQRYVNTLLKLIPPVLGLQEQLRQAVQSGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEPDKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSSLYDKLGRLLTNTEQPSTWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINNVLPLVLQALGNPELSISSVSTLKKICRECKYDLPPYAANIVAVSQEVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLITPYIQQLEKLADETPNPSNKLAIIHILGLLSNLFTTLDISHHDDDHESTEVKKLPVQQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVESVCAIFEKSVKTLLDDFAPMVPQLCEMLGQMYSTIPQASAIDLTRQLVHIFAHEPAHFPPIKALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCSNLDVKALFHCGVLSLKFPEAPTVKASCGFFTELLPRCGEIAPVGQVVHENGKVLLQAVLEGVGGQASRSLMDHFAEILFALNKHCFSYLSIWIKEAMQQDGFPSARVSPEQKETFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTEYTADY", "length": 958, "header": "sp|Q5ZIC8-1|IPO13_CHICK Isoform 1 of Importin-13 OS=Gallus gallus OX=9031 GN=IPO13 PE=2 SV=1 CANONICAL=Q5ZIC8-1" }, "isoforms": [ { "isoform_ac": "Q5ZIC8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8/entry#Q5ZIC8-1", "sequence": { "sequence": "MERRAEAPPPPQGLDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWLLLNMDKVPEIQYSAPAPCTSRSPATGTTSLPDQYESLKSQLFTHITRFAGGSKIVLTRLCVALASLALSMMPEAWPCAVADMVRMFQAEDSNVDGRARCLALLELLTVLPEEFQTSRLPQYRKGQVRSVLAQECGSVFPLLEQLLQQQDSPGFIKQKVLKCFSSWVQLEIPLMDCENLIQAAFTSLQDPELFDTAVEAVVNAISQPDAQRYVNTLLKLIPPVLGLQEQLRQAVQSGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEPDKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSSLYDKLGRLLTNTEQPSTWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINNVLPLVLQALGNPELSISSVSTLKKICRECKYDLPPYAANIVAVSQEVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLITPYIQQLEKLADETPNPSNKLAIIHILGLLSNLFTTLDISHHDDDHESTEVKKLPVQQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVESVCAIFEKSVKTLLDDFAPMVPQLCEMLGQMYSTIPQASAIDLTRQLVHIFAHEPAHFPPIKALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCSNLDVKALFHCGVLSLKFPEAPTVKASCGFFTELLPRCGEIAPVGQVVHENGKVLLQAVLEGVGGQASRSLMDHFAEILFALNKHCFSYLSIWIKEAMQQDGFPSARVSPEQKETFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTEYTADY", "length": 958, "header": "sp|Q5ZIC8-1|IPO13_CHICK Isoform 1 of Importin-13 OS=Gallus gallus OX=9031 GN=IPO13 PE=2 SV=1 CANONICAL=Q5ZIC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424573", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIC8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 958, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIC8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIC8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 313, "end_pos": 315 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZID0-1", "uniprot_ac": "Q5ZID0", "uniprot_id": "NMRL1_CHICK", "mass": { "chemical_mass": 32689.0, "monoisotopic_mass": 32689.0 }, "refseq": { "ac": "NP_001025816", "name": "nmrA-like family domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025816" }, "gene_names": [ { "name": "NMRAL1", "type": "recommended", "evidence": [ { "id": "Q5ZID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0" } ] }, { "name": "NMRAL1", "type": "synonym", "evidence": [ { "id": "NP_001025816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025816" } ] }, { "name": "RCJMB04_27o15", "type": "synonym", "evidence": [ { "id": "Q5ZID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0" } ] } ], "protein_names": [ { "name": "NmrA-like family domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0/entry#names_and_taxonomy" } ] }, { "name": "NmrA-like family domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001025816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025816" } ] }, { "name": "nmrA-like family domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001025816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025816" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720854.1, SRR13267659.79910.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3109050, SAMN02738220 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001025816.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025816" } ] }, { "annotation": "Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZID0", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZID0", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NMRAL1", "url": "https://www.uniprot.org/uniprotkb/Q5ZID0", "locus": { "chromosome": "14", "start_pos": 12752216, "end_pos": 12757162, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016644", "url": "https://www.ensembl.org/id/ENSGALG00010016644" } ] } } ], "crossref": [ { "id": "Q5ZID0", "url": 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The reference sequence was derived from JAENSK010000339.1. On Nov 12, 2021 this sequence version replaced NP_001026072.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026072", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026072" } ] }, { "annotation": "Probably involved in signal transduction, in the nervous system. Required for the spatial learning process. 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"MASGPGAATLKKCLEVLRDARNDSEQLAALLLVTKAVRAGDLDSKTRRQIFDAIGFTFPNRLLSSRQAPPGCPEHTFRALGLTLLACFCTEPELAGHSQVLNKIPTFADVLLSPCQPDCTSMVDDAYQCLAAVLATPRGPREMVTKGAASALCQAYVNGGYGSERALALLLGLLAVSEAKCWQRDAPHLLAVLSKLSEEFVRAEDGSQFELCELLPRFIPLSPPLAEVSQGSECVRQLYKGLASILGSKLSQSQRDPALKLAASLTQACGSEWIPAGSTGSKFLALLVNLACVEVRLTLEEPEPLEVEGKKEVVTACYVLIEMGIQECLKEEESLLDEAQRMQLMRIMEEAFGAVVFYLRQVKEEELQDPFVFASVRILGAWMAEETSSLKQEICELLPFLVRYARKLFKEGGPAENLPQTAGLVSSDSSILGQDALRFLLPGFCHLTAEDRPRDILISEGAPALLCDYFLHQWGVLTSQPGSLTSTEMSLQTLCGIFLNLVVTAPNLIRQEKTFSSLMDTLLKSLPFLLPQKDHLVLAANIATLGLVMARILSSSAVLQKTGSAKEFFRATICFLSQAHTAQADPGSHGLALAVSPAYVSAWDDIRELWFLGMQALASCVPLFPWLPQAVLQAQWLEELSELLTRVTAASVDFELIAAFQGVLVGLARASKPCREVILSHHGEEWANLYGMAALEQCLSKQ", "length": 702, "header": "sp|Q5ZIG0-1|NCDN_CHICK Isoform 1 of Neurochondrin OS=Gallus gallus OX=9031 GN=NCDN PE=2 SV=1 CANONICAL=Q5ZIG0-1" }, "isoforms": [ { "isoform_ac": "Q5ZIG0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIG0/entry#Q5ZIG0-1", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/Q5ZIG0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIG0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIG0" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIG0", "url": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIH0-1", "uniprot_ac": "Q5ZIH0", "uniprot_id": "INT11_CHICK", "mass": { "chemical_mass": 68188.0, "monoisotopic_mass": 68188.0 }, "refseq": { "ac": "NP_001012854", "name": "integrator complex subunit 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" }, "gene_names": [ { "name": "INTS11", "type": "recommended", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0" } ] }, { "name": "CPSF3L", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" }, { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0" } ] }, { "name": "INTS11", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] }, { "name": "RCJMB04_26e19", "type": "synonym", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 11", "type": "recommended", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#names_and_taxonomy" } ] }, { "name": "3.1.27.-", "type": "synonym", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#names_and_taxonomy" } ] }, { "name": "CPSF3-like protein", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" }, { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#names_and_taxonomy" } ] }, { "name": "Cleavage and polyadenylation-specific factor 3-like protein", "type": "synonym", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#names_and_taxonomy" } ] }, { "name": "Int11", "type": "synonym", "evidence": [ { "id": "Q5ZIH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#names_and_taxonomy" } ] }, { "name": "cleavage and polyadenylation specific factor 3-like", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] }, { "name": "cleavage and polyadenylation-specific factor 3-like protein", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] }, { "name": "int11", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] }, { "name": "integrator complex subunit 11", "type": "synonym", "evidence": [ { "id": "NP_001012854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720814.1, HAEK01013058.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Mar 14, 2005 this sequence version replaced XP_417579.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854" } ] }, { "annotation": "RNA endonuclease component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs). Within the integrator complex, INTS11 constitutes the RNA endonuclease subunit that degrades exiting nascent RNA transcripts.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0#function" }, { "database": "UniProtKB", "id": "Q5TA45", "url": "https://www.uniprot.org/uniprotkb/Q5TA45#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS11", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0", "locus": { "chromosome": "21", "start_pos": 2342546, "end_pos": 2334855, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018044", "url": "https://www.ensembl.org/id/ENSGALG00010018044" } ] } } ], "crossref": [ { "id": "Q5ZIH0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419418", "url": "https://www.ncbi.nlm.nih.gov/gene/419418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419418", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLDGMIW", "url": "https://omabrowser.org/oma/group/YLDGMIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIH0", "url": "https://www.orthodb.org/?gene=Q5ZIH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11203:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11203:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIH0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIH0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIH0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEIKVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGYNDDRRFPDFSYITQNGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTKAICPILLEDYRKITVDKKGETNFFTSQMIKDCMKKVVAVHLHQTVQVDEELEIKAYYAGHVLGAAMFQIKVGCESVVYTGDYNMTPDRHLGAAWIDKCRPDLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKAPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQILEVKMQVEYMSFSAHADAKGIMQLIRQAEPRNVLLVHGEAKKMEFLKQKIEQEFHVNCYMPANGETTTIFTNPSIPVDISLGLLKRETAIGLLPDAKKPKLMHGTLIMKDNSFRLVSPEQALKELGLAEHQLRFTCRVHIQDPRKEHETVLRVYNHLKGVLKDYSVQHLPDGSITVESILIQATAHSEDQGTKVLLVSWTYQDEELGSYLTSLLKKGLPQSTS", "length": 600, "header": "sp|Q5ZIH0-1|INT11_CHICK Isoform 1 of Integrator complex subunit 11 OS=Gallus gallus OX=9031 GN=INTS11 PE=2 SV=1 CANONICAL=Q5ZIH0-1" }, "isoforms": [ { "isoform_ac": "Q5ZIH0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0/entry#Q5ZIH0-1", "sequence": { "sequence": "MPEIKVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGYNDDRRFPDFSYITQNGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTKAICPILLEDYRKITVDKKGETNFFTSQMIKDCMKKVVAVHLHQTVQVDEELEIKAYYAGHVLGAAMFQIKVGCESVVYTGDYNMTPDRHLGAAWIDKCRPDLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKAPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQILEVKMQVEYMSFSAHADAKGIMQLIRQAEPRNVLLVHGEAKKMEFLKQKIEQEFHVNCYMPANGETTTIFTNPSIPVDISLGLLKRETAIGLLPDAKKPKLMHGTLIMKDNSFRLVSPEQALKELGLAEHQLRFTCRVHIQDPRKEHETVLRVYNHLKGVLKDYSVQHLPDGSITVESILIQATAHSEDQGTKVLLVSWTYQDEELGSYLTSLLKKGLPQSTS", "length": 600, "header": "sp|Q5ZIH0-1|INT11_CHICK Isoform 1 of Integrator complex subunit 11 OS=Gallus gallus OX=9031 GN=INTS11 PE=2 SV=1 CANONICAL=Q5ZIH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419418", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I420-1", "protein_name": "Integrator complex subunit 11", "gene_name": "Ints11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVGISLGLLKREMVQGLLPEAKKPRLLHGTLVMKDSSFRLVSSEQALKELGLAEHQLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSEDPGTKVLLVSWTYQDEELGSFLTALLKNGLPQAPS", "length": 600 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3MHC2-1", "protein_name": "Integrator complex subunit 11", "gene_name": "Ints11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVGISLGLLKREMVQGLLPEAKKPRLLHGTLIMKDNNFRLVSSEQALKELGLAEHQLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSEDPGTKVLLVSWTYQDEELGSFLTALLKNGLPQAPS", "length": 600 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q503E1-1", "protein_name": "Integrator complex subunit 11", "gene_name": "cpsf3l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDIKVTPLGAGQDVGRSCILVSIGGKNIMLDCGMHMGFNDDRRFPDFSYITQNGRLTEFLDCVIISHFHLDHCGALPYMSEMVGYDGPIYMTHPTKAICPILLEDFRKITVDKKGETNFFTSQMIKDCMKKVVPLNLHQTVQVDDELEIKAYYAGHVLGAAMVQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPDILISESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKAPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRSYADNPGPMVVFATPGMLHAGQSLQIFKKWAGNEKNMVIMPGYCVQGTVGHKILNGQKKLEMEGRATLDVKLQVEYMSFSAHADAKGIMQLIRMAEPRNMLLVHGEAKKMEFLKDKIEQEFSISCFMPANGETTTIVTNPSVPVDISLNLLKREMALGGPLPDAKRPRTMHGTLIMKDNSLRLVSPEQALKELGLNEHQLRFTCRVQLHDPHSDTDTLSRIYTHLKSVLKSYSIQHVPDGTVIVESIVIKVTSSAEEPNLKVILLSWSYQDEELGSFLSTLLKKGLPS", "length": 598 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5TA45-1", "protein_name": "Integrator complex subunit 11", "gene_name": "INTS11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEIRVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGLLKREMAQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKGLPQAPS", "length": 600 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8GUU3-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 3-II", "gene_name": "CPSF73-II", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIDCLVLGAGQEIGKSCVVVTINGKKIMFDCGMHMGCDDHNRYPNFSLISKSGDFDNAISCIIITHFHMDHVGALPYFTEVCGYNGPIYMSYPTKALSPLMLEDYRRVMVDRRGEEELFTTTHIANCMKKVIAIDLKQTIQVDEDLQIRAYYAGHVLGAVMVYAKMGDAAIVYTGDYNMTTDRHLGAAKIDRLQLDLLISESTYATTIRGSKYPREREFLQAVHKCVAGGGKALIPSFALGRAQELCMLLDDYWERMNIKVPIYFSSGLTIQANMYYKMLISWTSQNVKEKHNTHNPFDFKNVKDFDRSLIHAPGPCVLFATPGMLCAGFSLEVFKHWAPSPLNLVALPGYSVAGTVGHKLMAGKPTTVDLYNGTKVDVRCKVHQVAFSPHTDAKGIMDLTKFLSPKNVVLVHGEKPSMMILKEKITSELDIPCFVPANGETVSFASTTYIKANASDMFLKSCSNPNFKFSNSTQLRVTDHRTADGVLVIEKSKKAKIVHQDEISEVLHEKNHVVSLAHCCPVKVKGESEDDDVDLIKQLSAKILKTVSGAQIHESENCLQVASFKGSLCLKDKCMHRSSSSSSEAVFLCCNWSIADLELGWEIINAIKLNH", "length": 613 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CWS4-1", "protein_name": "Integrator complex subunit 11", "gene_name": "Ints11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVGISLGLLKREMVQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSEDPGTKVLLVSWTYQDEELGSFLTTLLKNGLPQAPS", "length": 600 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAH9-1", "protein_name": "Integrator complex subunit 11", "gene_name": "IntS11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPDIKITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSHIDCVIISHFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQMIKDCMKKVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPDRHLGAAWIDKCRPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYWERMNLKYPIYFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFKHIKPFDKAYIDNPGAMVVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVVEVKMAVEYMSFSAHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEFNLETYMPANGETCVISTPVKIPVDASVSLLKAEARSYNAQPPDPKRRRLIHGVLVMKDNRIMLQNLTDALKEIGINRHVMRFTSKVKMDDSGPVIRTSERLKTLLEEKLAGWTVTMQENGSIAIESVEVKVEEDEKDPKQKNILISWTNQDEDIGAYILNVLQNMC", "length": 597 }, "evidence": [ { "id": "Q5ZIH0", "url": "https://omabrowser.org/oma/group/Q5ZIH0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { 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"evidence": [ { "id": "Q5ZIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH2" } ] } ], "protein_names": [ { "name": "Vacuolar fusion protein MON1 homolog A", "type": "recommended", "evidence": [ { "id": "Q5ZIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH2/entry#names_and_taxonomy" } ] }, { "name": "MON1 secretory trafficking family member A", "type": "synonym", "evidence": [ { "id": "NP_001025758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025758" } ] }, { "name": "vacuolar fusion protein MON1 homolog A", "type": "synonym", "evidence": [ { "id": "NP_001025758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025758" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738223 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000251.1. On Dec 3, 2021 this sequence version replaced NP_001025758.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025758" } ] }, { "annotation": "Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIH2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH2#function" }, { "database": "UniProtKB", "id": "Q6PDG8", "url": "https://www.uniprot.org/uniprotkb/Q6PDG8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIH2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MON1A", "url": "https://www.uniprot.org/uniprotkb/Q5ZIH2", "locus": { "chromosome": "12", "start_pos": 2754322, "end_pos": 2759194, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027320", "url": "https://www.ensembl.org/id/ENSGALG00010027320" } ] } } ], "crossref": [ { "id": "Q5ZIH2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "415929", "url": "https://www.ncbi.nlm.nih.gov/gene/415929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415929", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIH2", "url": "https://www.orthodb.org/?gene=Q5ZIH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIH2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIH2", 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Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIJ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIJ0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428248", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428248", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIJ0", "url": "https://www.uniprot.org/uniprotkb/Q5ZIJ0" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": 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protein bS6m isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026657" } ] }, { "name": "small ribosomal subunit protein bS6m", "type": "synonym", "evidence": [ { "id": "NP_001026657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026657" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720792.1, HAEL01000624.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000020.1. On Dec 3, 2021 this sequence version replaced NP_001026657.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026657" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIJ2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIJ2", "locus": { "chromosome": "1", "start_pos": 105789919, "end_pos": 105678442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012648", "url": "https://www.ensembl.org/id/ENSGALG00010012648" } ] } } ], "crossref": [ { "id": "Q5ZIJ2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15465", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15465", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427978", "url": "https://www.ncbi.nlm.nih.gov/gene/427978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427978", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATHFTIT", "url": "https://omabrowser.org/oma/group/ATHFTIT/", "database": "OMA", "categories": [ 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRYELALILKAMQRPETAAVLKRTVEALMERGAIVRNLENLGERALPYKISKHNHRHRRGGYFLVDLEGPPSIVSTMMDHLGRDIDIIRRAFIKYPVSKTEECSGIVPVNCEDKLIPKKK", "length": 121, "header": "sp|Q5ZIJ2-1|RT06_CHICK Isoform 1 of Small ribosomal subunit protein bS6m OS=Gallus gallus OX=9031 GN=MRPS6 PE=2 SV=3 CANONICAL=Q5ZIJ2-1" }, "isoforms": [ { "isoform_ac": "Q5ZIJ2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIJ2/entry#Q5ZIJ2-1", "sequence": { "sequence": "MPRYELALILKAMQRPETAAVLKRTVEALMERGAIVRNLENLGERALPYKISKHNHRHRRGGYFLVDLEGPPSIVSTMMDHLGRDIDIIRRAFIKYPVSKTEECSGIVPVNCEDKLIPKKK", "length": 121, "header": "sp|Q5ZIJ2-1|RT06_CHICK Isoform 1 of Small ribosomal subunit protein bS6m OS=Gallus gallus OX=9031 GN=MRPS6 PE=2 SV=3 CANONICAL=Q5ZIJ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function 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"MPRYELALILKAMRRPETAAALKRTIESLMDRGAIVRNLENLGERALPYRISSHSQQHSRGGWWPSEFHLVVYRCIKLYTHNGHIESTFLHWAAEASPQGGDLLPRYFLVDFYAPTNAVESMLEHLARDTDVVRPNIVKHPLTQEVKECDGIVPVPLEEKLYSTKRRKK", "length": 169 }, "evidence": [ { "id": "Q5ZIJ2", "url": "https://omabrowser.org/oma/group/Q5ZIJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58064-1", "protein_name": "Small ribosomal subunit protein bS6m", "gene_name": "Mrps6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRYELALILKAMRRPETAAALKRTIESLMDRGAIVRNLESLGERALPYRISSHSQQHSRGGYFLVDFYAPTSAVENILEHLARDIDVVRPNIVKHPLTQEVKECDGIVPVPLEEKLYSTKRRKK", "length": 125 }, "evidence": [ { "id": "Q5ZIJ2", "url": "https://omabrowser.org/oma/group/Q5ZIJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P82931-1", "protein_name": "Small ribosomal subunit protein bS6m", "gene_name": "MRPS6", "tax_id": 9913, "organism": "Bos taurus", "sequence": 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On Aug 8, 2005 this sequence version replaced XP_420154.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026282" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDZD11", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2", "locus": { "chromosome": "4", "start_pos": 1222700, "end_pos": 1226718, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017754", "url": "https://www.ensembl.org/id/ENSGALG00010017754" } ] } } ], "crossref": [ { "id": "Q5ZIK2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004198", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06752", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06752", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422153", "url": "https://www.ncbi.nlm.nih.gov/gene/422153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422153", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RGGREHN", "url": "https://omabrowser.org/oma/group/RGGREHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIK2", "url": "https://www.orthodb.org/?gene=Q5ZIK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIK2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIK2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIK2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGRLPYDDFPVVFLPPYESPPAWVPPHERVYHPDYNNELTQFLPRTVVLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLSVNDVDFQDIEHSKAVEILKTAREITMRVRYFPYSKCLLAPNLVT", "length": 140, "header": "sp|Q5ZIK2-1|PDZ11_CHICK Isoform 1 of PDZ domain-containing protein 11 OS=Gallus gallus OX=9031 GN=PDZD11 PE=2 SV=1 CANONICAL=Q5ZIK2-1" }, "isoforms": [ { "isoform_ac": "Q5ZIK2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2/entry#Q5ZIK2-1", "sequence": { "sequence": "MEGRLPYDDFPVVFLPPYESPPAWVPPHERVYHPDYNNELTQFLPRTVVLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLSVNDVDFQDIEHSKAVEILKTAREITMRVRYFPYSKCLLAPNLVT", "length": 140, "header": "sp|Q5ZIK2-1|PDZ11_CHICK Isoform 1 of PDZ domain-containing protein 11 OS=Gallus gallus OX=9031 GN=PDZD11 PE=2 SV=1 CANONICAL=Q5ZIK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422153", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422153", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I1F8-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "Pdzd11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDSRISYDDYPVVFLPAYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH", "length": 140 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q32LE7-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "PDZD11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSRIPYDDYPVVFLPAYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH", "length": 140 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5EBL8-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "PDZD11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRIPYDDYPVVFLPAYENPPAWIPPHERVHHPDYNNELTQFLPRTITLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH", "length": 140 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXB2-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "pdzd11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQKIPYDDYQLPVVFLPSYENPPAWIPPQERIHHPDYNNELAQFLPRTIVLKKPPGAQLGFNIRGGKASQLGIFISKVVPDSDAHRAGLQEGDQVLSVNEVDFQDIEHSRAVEILKTAREILMKVRYFPYNYQRQKERTVH", "length": 142 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6QA76-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "PDZD11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSRIPYDDYPVVFLPAYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH", "length": 140 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9CZG9-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "Pdzd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNRIPYDDYPVVFLPAYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH", "length": 140 }, "evidence": [ { "id": "Q5ZIK2", "url": "https://omabrowser.org/oma/group/Q5ZIK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "pore complex", "id": "GO:0046930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046930", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "pore complex assembly", "id": "GO:0046931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046931", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "synaptic vesicle transport", "id": "GO:0048489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIK2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 140, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIK2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIK2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK2" }, { "id": "PRU00143", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00143" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000255", "start_pos": 47, "end_pos": 129, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIK6-1", "uniprot_ac": "Q5ZIK6", "uniprot_id": "BSDC1_CHICK", "mass": { "chemical_mass": 49419.0, "monoisotopic_mass": 49419.0 }, "refseq": { "ac": "NP_001012860", "name": "BSD domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860" }, "gene_names": [ { "name": "BSDC1", "type": "recommended", "evidence": [ { "id": "Q5ZIK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" } ] }, { "name": "BSDC1", "type": "synonym", "evidence": [ { "id": "NP_001012860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860" } ] }, { "name": "RCJMB04_25f24", "type": "synonym", "evidence": [ { "id": "Q5ZIK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" } ] } ], "protein_names": [ { "name": "BSD domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZIK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6/entry#names_and_taxonomy" } ] }, { "name": "BSD domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001012860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720778.1, HAEL01009012.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000339.1. On Sep 23, 2021 this sequence version replaced NP_001012860.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BSDC1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6", "locus": { "chromosome": "23", "start_pos": 5557453, "end_pos": 5563868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017578", "url": "https://www.ensembl.org/id/ENSGALG00010017578" } ] } } ], "crossref": [ { "id": "Q5ZIK6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "419658", "url": "https://www.ncbi.nlm.nih.gov/gene/419658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIK6", "url": "https://www.orthodb.org/?gene=Q5ZIK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIK6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIK6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIK6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIK6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGEDAGWWRSWLQQSYQAVKEKSTEALEFMKRDLAEFTQVVQHDTACTIAATASVVKDRLARTEASGATEKVRKGISDFLGVISDTFAPSPDKTIDCDVITLMATPTGTTEPYDSAKARLYSLQSDPATYCNEPDGPAELLEAWLSRFSLEEKKGEIAELLATSPSIRALYTKMVPAAVSHSEFWQRYFYKVHRLEQDEVRREALKQRAEQSIHQEEPGWEEDEEEFLGMSPLPCANVKFPQAAEKASVSAALEGSQPSVHKGPSGESWAILPPELAPAEGSPSESSESVSLVTQIANPASVPVVQLQTGVQPSGNRDLSQRLLEATSEEQSPLPKPPEPGHPSAAAQEPAVCSEQTAVTGPKEVESKAQGRTETLKEEGPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQLALSKVEVSGELEDEEWEDWE", "length": 451, "header": "sp|Q5ZIK6-1|BSDC1_CHICK Isoform 1 of BSD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=BSDC1 PE=2 SV=1 CANONICAL=Q5ZIK6-1" }, "isoforms": [ { "isoform_ac": "Q5ZIK6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6/entry#Q5ZIK6-1", "sequence": { "sequence": "MAEGEDAGWWRSWLQQSYQAVKEKSTEALEFMKRDLAEFTQVVQHDTACTIAATASVVKDRLARTEASGATEKVRKGISDFLGVISDTFAPSPDKTIDCDVITLMATPTGTTEPYDSAKARLYSLQSDPATYCNEPDGPAELLEAWLSRFSLEEKKGEIAELLATSPSIRALYTKMVPAAVSHSEFWQRYFYKVHRLEQDEVRREALKQRAEQSIHQEEPGWEEDEEEFLGMSPLPCANVKFPQAAEKASVSAALEGSQPSVHKGPSGESWAILPPELAPAEGSPSESSESVSLVTQIANPASVPVVQLQTGVQPSGNRDLSQRLLEATSEEQSPLPKPPEPGHPSAAAQEPAVCSEQTAVTGPKEVESKAQGRTETLKEEGPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQLALSKVEVSGELEDEEWEDWE", "length": 451, "header": "sp|Q5ZIK6-1|BSDC1_CHICK Isoform 1 of BSD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=BSDC1 PE=2 SV=1 CANONICAL=Q5ZIK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419658", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 451, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIK6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZIK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK6" }, { "id": "PRU00036", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BSD", "eco_id": "ECO_0000255", "start_pos": 146, "end_pos": 198, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIK9-1", "uniprot_ac": "Q5ZIK9", "uniprot_id": "COPE_CHICK", "mass": { "chemical_mass": 34369.0, "monoisotopic_mass": 34369.0 }, "refseq": { "ac": "NP_001006339", "name": "coatomer subunit epsilon", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" }, "gene_names": [ { "name": "COPE", "type": "recommended", "evidence": [ { "id": "Q5ZIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ] }, { "name": "COPE", "type": "synonym", "evidence": [ { "id": "NP_001006339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" } ] }, { "name": "RCJMB04_25f12", "type": "synonym", "evidence": [ { "id": "Q5ZIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ] } ], "protein_names": [ { "name": "Coatomer subunit epsilon", "type": "recommended", "evidence": [ { "id": "Q5ZIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9/entry#names_and_taxonomy" } ] }, { "name": "Epsilon-COP", "type": "synonym", "evidence": [ { "id": "Q5ZIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9/entry#names_and_taxonomy" } ] }, { "name": "Epsilon-coat protein", "type": "synonym", "evidence": [ { "id": "Q5ZIK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9/entry#names_and_taxonomy" } ] }, { "name": "coatomer subunit epsilon", "type": "synonym", "evidence": [ { "id": "NP_001006339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" } ] }, { "name": "epsilon-COP", "type": "synonym", "evidence": [ { "id": "NP_001006339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" } ] }, { "name": "epsilon-coat protein", "type": "synonym", "evidence": [ { "id": "NP_001006339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720775.1, HAEK01105858.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000376.1. On Jan 13, 2005 this sequence version replaced XP_418235.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339" } ] }, { "annotation": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COPE", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9", "locus": { "chromosome": "28", "start_pos": 4175040, "end_pos": 4169075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028170", "url": "https://www.ensembl.org/id/ENSGALG00010028170" } ] } } ], "crossref": [ { "id": "Q5ZIK9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003153", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420117", "url": "https://www.ncbi.nlm.nih.gov/gene/420117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420117", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420117", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIVLSQH", "url": "https://omabrowser.org/oma/group/MIVLSQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIK9", "url": "https://www.orthodb.org/?gene=Q5ZIK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10805:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10805:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIK9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIK9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIK9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGAGAGPAGQGGEADELFDVKNSFYIGAYQAAINEAQRIKPSNPEKETERDVFLFRSYIAQRKYGVVLDEIKANASPELQAVRMFAEYLSNESQRDAIVADLDKKMAKSVDVANTTFLLMAASIYFHDKNPDAALRTLHQGESLECMAMMIQILLKLDRLDLARKELKKMQEQDEDATLTQLATAWVNLAIGGEKLQDAYYIFQEMADKCSSTLLLLNGQAACYMAQGKWDDAEGVLQEALDKDSGHPETLINFVVLSQHLGKPPEVTNRYLSQLKDAHKNHPFIKEYQAKENDFDRLAMQYAPSA", "length": 308, "header": "sp|Q5ZIK9-1|COPE_CHICK Isoform 1 of Coatomer subunit epsilon OS=Gallus gallus OX=9031 GN=COPE PE=2 SV=1 CANONICAL=Q5ZIK9-1" }, "isoforms": [ { "isoform_ac": "Q5ZIK9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9/entry#Q5ZIK9-1", "sequence": { "sequence": "MASGAGAGPAGQGGEADELFDVKNSFYIGAYQAAINEAQRIKPSNPEKETERDVFLFRSYIAQRKYGVVLDEIKANASPELQAVRMFAEYLSNESQRDAIVADLDKKMAKSVDVANTTFLLMAASIYFHDKNPDAALRTLHQGESLECMAMMIQILLKLDRLDLARKELKKMQEQDEDATLTQLATAWVNLAIGGEKLQDAYYIFQEMADKCSSTLLLLNGQAACYMAQGKWDDAEGVLQEALDKDSGHPETLINFVVLSQHLGKPPEVTNRYLSQLKDAHKNHPFIKEYQAKENDFDRLAMQYAPSA", "length": 308, "header": "sp|Q5ZIK9-1|COPE_CHICK Isoform 1 of Coatomer subunit epsilon OS=Gallus gallus OX=9031 GN=COPE PE=2 SV=1 CANONICAL=Q5ZIK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:420117", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420117", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A9R8-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "Cope", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPAPGAVSGSSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENRRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNPDAALRTLHQGDGLECTAMTIQILLKLDRLDLARKELKRMQEQDEDATLTQLATAWVNLAMGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRTHPFIKEYQAKENDFDRLALQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S7E1-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "COPE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKPSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAIRMFAEYLASDSRRDAIVAELDREMSRSVDVTNTTFLLMAASIYFHDQNPDAALRTLHQGDSLECMAMTVQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVNLAVGGEKLQDAYYIFQEMADKCSSTLLLLNGQAACHMAQGRWEAAEGVLQEALDKDSSHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRTHPFIKEYHAKENDFDRLVLQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14579-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "COPE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFLLMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRLVLQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O89079-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "Cope", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPVPGAVSGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPEREVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASENQRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNPDAALRTLHQGDGLECMAMTIQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVNLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRLAMQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q28104-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "COPE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKPSSPERDVERDVFLYRAYLAQRKYGVVLDEIKPSSAPELQAVRMFAEYLASDSRRDAIVAELDREMSRSVDVTNTTFLLMAASIYFYDQNPDAALRTLHQGDSLECMAMTVQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVSLAAGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGVLQEALDKDSGHPETLINLVVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYRAKENDFDRLVLQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55FU2-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "cope", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDILFESKNYFYLGNYQSTINEINKKSRQIIEKSLKAESDYFLYRCYIAQGNYDLVLQETKNNRGSGEDPTIAGLQLLASYLSKPDENREGTLITITQWISDGVVKFNYHLQVIIATIYFNEQLYDEALQILNNCDHIEGLSMLIQIFLKIDRLDLAQKAYDTMKKIIDPDATPALLSLAWINIYNGEEKLKSALSSFEEMAERYGPTPLLLNGQAVCAIGMKRFEKAESLLLESIEKNPKNSDTLANLINCYINMKKPNEIIQRFINQLKTLSPKHDWTSAVNEAEALFEVSKSRFN", "length": 300 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q60445-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "COPE", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPPAPGAASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPDREVERDVFLYRAYIAQRKYGVVLDEIKPSSAPELQAVRMFADYLATENRRDAIVVELDREMSRSVDVTNTTFLLMAASVYFHDQNPDAALRTLHQGDSLECMAMTIQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVNLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRTHPFIKEYQAKENDFDRLALQYAPSA", "length": 308 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9SA78-1", "protein_name": "Coatomer subunit epsilon-1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASMAGPDHLFNLRNHFYLGAYQAAINNSEIPNLSQEDIVERDCLVHRAYIALGSYQLVISEIDEAAATPLQAVKLLAMYLSSPENKESTISSLREWLADPTVGNNAIIRLIAGTIFMHEEDYNEALKHTHSGGTMDLHALNVQIFIKMHRSDFAEKQLRVMQQIDEDHTLTQLASAWLNLAVGGSKIQEAYLIFQDFSEKYPMTSLILNGKAVCCMHMGNFEEAETLLLEALNKDAKDPETLANLVVCSLHVGKSSSRYLNQLKLSHPEHVLVKRAASAEDNFERALQSFA", "length": 292 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y0Y5-1", "protein_name": "Coatomer subunit epsilon", "gene_name": "epsilonCOP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRQQNEEDTNSVLFDARNEYYIGNFMGSINFVLPEQGTAGPELLSYMYLSYLAIDSGRIVASDIKEGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETNIWHLATAIVYCHDGQFENALKILHGSTNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQDAFHIYQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTGKPTEAITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQYDVEGGEKLLAV", "length": 306 }, "evidence": [ { "id": "Q5ZIK9", "url": "https://omabrowser.org/oma/group/Q5ZIK9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIK9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIK9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIK9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIK9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIL4-1", "uniprot_ac": "Q5ZIL4", "uniprot_id": "STRBP_CHICK", "mass": { "chemical_mass": 73372.0, "monoisotopic_mass": 73372.0 }, "refseq": { "ac": "NP_001025851", "name": "spermatid perinuclear RNA-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025851" }, "gene_names": [ { "name": "STRBP", "type": "recommended", "evidence": [ { "id": "Q5ZIL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ] }, { "name": "RCJMB04_25e3", "type": "synonym", "evidence": [ { "id": "Q5ZIL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ] }, { "name": "STRBP", "type": "synonym", "evidence": [ { "id": "NP_001025851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025851" } ] } ], "protein_names": [ { "name": "Spermatid perinuclear RNA-binding protein", "type": "recommended", "evidence": [ { "id": "Q5ZIL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4/entry#names_and_taxonomy" } ] }, { "name": "spermatid perinuclear RNA-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001025851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025851" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720770.1, SRR13267655.114393.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Aug 8, 2005 this sequence version replaced XP_415390.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025851" } ] }, { "annotation": "May be involved in normal spermatogenesis and sperm function. Binds to double-stranded DNA and RNA (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STRBP", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4", "locus": { "chromosome": "17", "start_pos": 9505017, "end_pos": 9560443, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028322", "url": "https://www.ensembl.org/id/ENSGALG00010028322" } ] } } ], "crossref": [ { "id": "Q5ZIL4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029927", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029927", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19909", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19909", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417105", "url": "https://www.ncbi.nlm.nih.gov/gene/417105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417105", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIL4", "url": "https://www.orthodb.org/?gene=Q5ZIL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIL4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIL4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIL4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWMDEKNKSVKCEGDVEAKEEAAESNAKDQSGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKEKPTKTLLCIVKDNLPIQIQKLTEEKYLVEEHVNEAAIIIRNTKEPKLTLKVILTSPLIRDEAEKKEGDSVAMKDPPDLLDRQKCLEALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCEREPTDALSDMTVQQKEAITHSAQHALRLSAFGQIYKVLEMDPLPSNKSFQKYSWSVADKEGTGSSALKRPFEDGVGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADVECVSSDEKSDNEGKNETVSSISSNNTGNSTADTSATLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKILPQQTKGVVNTAVSAAVQAVRGRGRGALTRGAFVGAAAATGYITPGYGAPYGYSTAAPAYGLPKRMVLLPVMKFPTYPVPHYSFF", "length": 672, "header": "sp|Q5ZIL4-1|STRBP_CHICK Isoform 1 of Spermatid perinuclear RNA-binding protein OS=Gallus gallus OX=9031 GN=STRBP PE=2 SV=1 CANONICAL=Q5ZIL4-1" }, "isoforms": [ { "isoform_ac": "Q5ZIL4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4/entry#Q5ZIL4-1", "sequence": { "sequence": "MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWMDEKNKSVKCEGDVEAKEEAAESNAKDQSGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKEKPTKTLLCIVKDNLPIQIQKLTEEKYLVEEHVNEAAIIIRNTKEPKLTLKVILTSPLIRDEAEKKEGDSVAMKDPPDLLDRQKCLEALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCEREPTDALSDMTVQQKEAITHSAQHALRLSAFGQIYKVLEMDPLPSNKSFQKYSWSVADKEGTGSSALKRPFEDGVGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADVECVSSDEKSDNEGKNETVSSISSNNTGNSTADTSATLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKILPQQTKGVVNTAVSAAVQAVRGRGRGALTRGAFVGAAAATGYITPGYGAPYGYSTAAPAYGLPKRMVLLPVMKFPTYPVPHYSFF", "length": 672, "header": "sp|Q5ZIL4-1|STRBP_CHICK Isoform 1 of Spermatid perinuclear RNA-binding protein OS=Gallus gallus OX=9031 GN=STRBP PE=2 SV=1 CANONICAL=Q5ZIL4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 631, "start_aa": "Thr", "end_pos": 631, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr631", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska 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"https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIL4", "url": "https://www.uniprot.org/uniprotkb/Q5ZIL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIL4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 672, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIL4-F1.pdb", "url_external": 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"id": "PRU01040", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01040" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DZF", "eco_id": "ECO_0000255", "start_pos": 5, "end_pos": 362, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 631 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 333, "end_pos": 335 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity). May function as a general inhibitor of the histone deacetylase HDAC1 (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIM6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIM6#function" }, { "database": "UniProtKB", "id": "Q9NY61", "url": "https://www.uniprot.org/uniprotkb/Q9NY61#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIM6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AATF", "url": "https://www.uniprot.org/uniprotkb/Q5ZIM6", "locus": { "chromosome": "19", "start_pos": 8926515, "end_pos": 8884570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029352", "url": "https://www.ensembl.org/id/ENSGALG00010029352" } ] } } ], "crossref": [ { "id": "Q5ZIM6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005420", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417653", "url": "https://www.ncbi.nlm.nih.gov/gene/417653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417653", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIM6", "url": "https://www.orthodb.org/?gene=Q5ZIM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08164", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08164", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIM6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIM6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZIM6", "url": "https://www.uniprot.org/uniprotkb/Q5ZIM6", "database": 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subject to final NCBI review. 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIR8-1", "uniprot_ac": "Q5ZIR8", "uniprot_id": "TIM9_CHICK", "mass": { "chemical_mass": 10483.0, "monoisotopic_mass": 10483.0 }, "refseq": { "ac": "NP_001258083", "name": "mitochondrial import inner membrane translocase subunit Tim9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" }, "gene_names": [ { "name": "TIMM9", "type": "recommended", "evidence": [ { "id": "Q5ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8" } ] }, { "name": "RCJMB04_23p13", "type": "synonym", "evidence": [ { "id": "Q5ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8" } ] }, { "name": "TIM9", "type": "synonym", "evidence": [ { "id": "NP_001258083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" }, { "id": "Q5ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8" } ] }, { "name": "TIMM9", "type": "synonym", "evidence": [ { "id": "NP_001258083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" } ] } ], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit Tim9", "type": "recommended", "evidence": [ { "id": "Q5ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import inner membrane translocase subunit Tim9", "type": "synonym", "evidence": [ { "id": "NP_001258083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" } ] }, { "name": "translocase of inner mitochondrial membrane 9 homolog", "type": "synonym", "evidence": [ { "id": "NP_001258083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" } ] }, { "name": "translocase of inner mitochondrial membrane 9-like protein", "type": "synonym", "evidence": [ { "id": "NP_001258083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01116528.1, BX274186.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On or before Sep 5, 2012 this sequence version replaced XP_003641468.1, XP_003641469.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001258083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083" } ] }, { "annotation": "Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIMM9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8", "locus": { "chromosome": "5", "start_pos": 54813163, "end_pos": 54805799, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017363", "url": "https://www.ensembl.org/id/ENSGALG00010017363" } ] } } ], "crossref": [ { "id": "Q5ZIR8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031966", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031966", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859762", "url": "https://www.ncbi.nlm.nih.gov/gene/100859762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859762", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDFLRMY", "url": "https://omabrowser.org/oma/group/QDFLRMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIR8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIR8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001258083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIR8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQISETDQIKQFKEFLGTYNKITENCFMDCIRDFTTREVKPEEITCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLSQPR", "length": 89, "header": "sp|Q5ZIR8-1|TIM9_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit Tim9 OS=Gallus gallus OX=9031 GN=TIMM9 PE=3 SV=1 CANONICAL=Q5ZIR8-1" }, "isoforms": [ { "isoform_ac": "Q5ZIR8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8/entry#Q5ZIR8-1", "sequence": { "sequence": "MAGQISETDQIKQFKEFLGTYNKITENCFMDCIRDFTTREVKPEEITCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLSQPR", "length": 89, "header": "sp|Q5ZIR8-1|TIM9_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit Tim9 OS=Gallus gallus OX=9031 GN=TIMM9 PE=3 SV=1 CANONICAL=Q5ZIR8-1" }, "locus": { "chromosome": "5", "start_pos": 54811430, "end_pos": 54808849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041900.1", "url": "https://www.ensembl.org/id/ENSGALT00010041900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024510.1", "url": "https://www.ensembl.org/id/ENSGALP00010024510.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIR8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIR8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:100859762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859762", "resource": "KEGG Pathway" }, { "id": "R-GGA-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SSK4-1", "protein_name": "Mitochondrial import inner membrane translocase subunit", "gene_name": "TIMM9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEENTCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLGQPR", "length": 89 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IMX4-1", "protein_name": "Mitochondrial import inner membrane translocase subunit", "gene_name": "Timm9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAQIPESDQIKQFKEFLGTYNRLTESCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLGQPR", "length": 89 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O74700-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM9", "gene_name": "TIM9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNAALGQGLGR", "length": 87 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KIV2-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "TIMM9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEETTCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLGQPR", "length": 89 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VYD7-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "Tim9a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKTPENIAIDQLDKDQIKTFSDFLMSYNKLSETCFTDCIRDFTTRDVKDSEEKCSLNCMEKYLKMNQRVSQRFQEFQVIAHENALAMAQKTGKL", "length": 95 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W762-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "timm9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAQVTESDQIKQFKEFLGTYNKLTENCFMDCVKDFTTREVKPEETTCSESCLQKYLKMTQRISMRFQEYHIQQNERWPQKPDY", "length": 84 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9WV97-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "Timm9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLGQPR", "length": 89 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WV98-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "Timm9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISVRFQEYHIQQNEALAAKAGLLGQPR", "length": 89 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XGX9-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM9", "gene_name": "TIM9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDASMMAGLDGLPEEDKAKMASMIDQLQLRDSLRMYNSLVERCFVDCVDSFTRKSLQKQEETCVMRCAEKFLKHTMRVGMRFAELNQNAPTQD", "length": 93 }, "evidence": [ { "id": "Q5ZIR8", "url": "https://omabrowser.org/oma/group/Q5ZIR8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y5J7-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim9", "gene_name": "TIMM9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"evidence": [ { "id": "NP_001292091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091" } ] }, { "name": "TAFII-150", "type": "synonym", "evidence": [ { "id": "Q5ZIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8/entry#names_and_taxonomy" } ] }, { "name": "TAFII150", "type": "synonym", "evidence": [ { "id": "Q5ZIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8/entry#names_and_taxonomy" } ] }, { "name": "TBP-associated factor 150 kDa", "type": "synonym", "evidence": [ { "id": "NP_001292091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091" }, { "id": "Q5ZIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8/entry#names_and_taxonomy" } ] }, { "name": "Transcription initiation factor TFIID 150 kDa subunit", "type": "synonym", "evidence": [ { "id": "Q5ZIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor TFIID 150 kDa subunit", "type": "synonym", "evidence": [ { "id": "NP_001292091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091" } ] }, { "name": "transcription initiation factor TFIID subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001292091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720696.1, SRR13267654.177668.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292091", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091" } ] }, { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8#function" }, { "database": "UniProtKB", "id": "Q6P1X5", "url": "https://www.uniprot.org/uniprotkb/Q6P1X5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TAF2", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8", "locus": { "chromosome": "2", "start_pos": 135619999, "end_pos": 135676687, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009363", "url": "https://www.ensembl.org/id/ENSGALG00010009363" } ] } } ], "crossref": [ { "id": "Q5ZIT8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09839", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09839", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428389", "url": "https://www.ncbi.nlm.nih.gov/gene/428389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428389", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428389", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIT8", "url": "https://www.orthodb.org/?gene=Q5ZIT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15137:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15137:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIT8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIT8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001292091", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIT8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGYVELTIFPTVANLNRIKLNSKQCRIYRVRVNDLEAAFIYNDPTLEVCHHESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKVHINFSLDQPKGGLHFVVPNMEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEYTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLAIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKQELDQIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQSDFMWQYQLRYERDVVAQEEAILALEKFPTPASRLALTDILEQEQCFYRVRMLACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMNFQSYFLQKTMPVAMALLRDVHNLCPKEVLMFILDLIKYNDNRKNKFSDNYYRAELIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLKAIRVLQKNGHVPSDPALFKSYAEYGHFVDVRIAALEAVVDYTKVDRSYEELQWLLTMVQNDPVPYIRHKILDMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVANNQEPVNTTNNHGQPVVFQNTEDDHLIKETASSISGHQQGVKRKADMPLGSPLEPGQILEKNEDSKVKLKIRFSNSQEEEEIDMDTVHDSQAFIYHHLNMLERPSTPGKEQSSGEVTMHPVSAAPLSVFSKESNSSKHSDHHHHHHHEHKKKKKKTLQVWIRP", "length": 1168, "header": "sp|Q5ZIT8-1|TAF2_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 2 OS=Gallus gallus OX=9031 GN=TAF2 PE=2 SV=1 CANONICAL=Q5ZIT8-1" }, "isoforms": [ { "isoform_ac": "Q5ZIT8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8/entry#Q5ZIT8-1", "sequence": { "sequence": "MNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGYVELTIFPTVANLNRIKLNSKQCRIYRVRVNDLEAAFIYNDPTLEVCHHESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKVHINFSLDQPKGGLHFVVPNMEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEYTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLAIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKQELDQIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQSDFMWQYQLRYERDVVAQEEAILALEKFPTPASRLALTDILEQEQCFYRVRMLACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMNFQSYFLQKTMPVAMALLRDVHNLCPKEVLMFILDLIKYNDNRKNKFSDNYYRAELIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLKAIRVLQKNGHVPSDPALFKSYAEYGHFVDVRIAALEAVVDYTKVDRSYEELQWLLTMVQNDPVPYIRHKILDMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVANNQEPVNTTNNHGQPVVFQNTEDDHLIKETASSISGHQQGVKRKADMPLGSPLEPGQILEKNEDSKVKLKIRFSNSQEEEEIDMDTVHDSQAFIYHHLNMLERPSTPGKEQSSGEVTMHPVSAAPLSVFSKESNSSKHSDHHHHHHHEHKKKKKKTLQVWIRP", "length": 1168, "header": "sp|Q5ZIT8-1|TAF2_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 2 OS=Gallus gallus OX=9031 GN=TAF2 PE=2 SV=1 CANONICAL=Q5ZIT8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 797, "start_aa": "Thr", "end_pos": 797, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr797", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428389", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428389", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIT8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1168, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIT8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIT8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46, 797 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1012, "end_pos": 1014 }, { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 566, "end_pos": 568 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIT9-1", "uniprot_ac": "Q5ZIT9", "uniprot_id": "MFSD1_CHICK", "mass": { "chemical_mass": 48162.0, "monoisotopic_mass": 48162.0 }, "refseq": { "ac": "NP_001026492", "name": "lysosomal dipeptide transporter MFSD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492" }, "gene_names": [ { "name": "MFSD1", "type": "recommended", "evidence": [ { "id": "Q5ZIT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ] }, { "name": "MFSD1", "type": "synonym", "evidence": [ { "id": "NP_001026492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492" } ] }, { "name": "RCJMB04_23j9", "type": "synonym", "evidence": [ { "id": "Q5ZIT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ] } ], "protein_names": [ { "name": "Lysosomal dipeptide transporter MFSD1", "type": "recommended", "evidence": [ { "id": "Q5ZIT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9/entry#names_and_taxonomy" } ] }, { "name": "Major facilitator superfamily domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZIT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9/entry#names_and_taxonomy" } ] }, { "name": "lysosomal dipeptide transporter MFSD1", "type": "synonym", "evidence": [ { "id": "NP_001026492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492" } ] }, { "name": "major facilitator superfamily domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720695.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720695.1. On Aug 8, 2005 this sequence version replaced XP_422820.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492" } ] }, { "annotation": "Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion (By similarity). Also essential for liver homeostasis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9#function" }, { "database": "UniProtKB", "id": "Q9DC37", "url": "https://www.uniprot.org/uniprotkb/Q9DC37#function" }, { "database": "UniProtKB", "id": "Q9H3U5", "url": "https://www.uniprot.org/uniprotkb/Q9H3U5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9", "locus": { "chromosome": "9", "start_pos": 22116914, "end_pos": 22128985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001181", "url": "https://www.ensembl.org/id/ENSGALG00010001181" } ] } } ], "crossref": [ { "id": "Q5ZIT9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009593", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425017", "url": "https://www.ncbi.nlm.nih.gov/gene/425017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425017", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIT9", "url": "https://www.orthodb.org/?gene=Q5ZIT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23512:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23512:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIT9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIT9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026492", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "79367", "url": "https://www.rhea-db.org/rhea/79367", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79371", "url": "https://www.rhea-db.org/rhea/79371", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79375", "url": "https://www.rhea-db.org/rhea/79375", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79379", "url": "https://www.rhea-db.org/rhea/79379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79383", "url": "https://www.rhea-db.org/rhea/79383", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79387", "url": "https://www.rhea-db.org/rhea/79387", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79391", "url": "https://www.rhea-db.org/rhea/79391", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79395", "url": "https://www.rhea-db.org/rhea/79395", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79399", "url": "https://www.rhea-db.org/rhea/79399", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79403", "url": "https://www.rhea-db.org/rhea/79403", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79407", "url": "https://www.rhea-db.org/rhea/79407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79411", "url": "https://www.rhea-db.org/rhea/79411", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79415", "url": "https://www.rhea-db.org/rhea/79415", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIT9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGDMKVNTARFMALYAWLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANDLLYC", "length": 442, "header": "sp|Q5ZIT9-1|MFSD1_CHICK Isoform 1 of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=2 SV=1 CANONICAL=Q5ZIT9-1" }, "isoforms": [ { "isoform_ac": "Q5ZIT9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9/entry#Q5ZIT9-1", "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGDMKVNTARFMALYAWLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANDLLYC", "length": 442, "header": "sp|Q5ZIT9-1|MFSD1_CHICK Isoform 1 of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=2 SV=1 CANONICAL=Q5ZIT9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:425017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425017", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" }, { "name": "dipeptide uniporter activity", "id": "GO:0160178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160178", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" }, { "name": "dipeptide transmembrane transport from lysosomal lumen to cytosol", "id": "GO:0141204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141204", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIT9", "url": "https://www.uniprot.org/uniprotkb/Q5ZIT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "79367", "name": "", "equation": "L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79367", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79367" } ] }, { "id": "79371", "name": "", "equation": "L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79371", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79371" } ] }, { "id": "79375", "name": "", "equation": "L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79375", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79375" } ] }, { "id": "79379", "name": "", "equation": "L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79379" } ] }, { "id": "79383", "name": "", "equation": "L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79383", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79383" } ] }, { "id": "79387", "name": "", "equation": "L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79387", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79387" } ] }, { "id": "79391", "name": "", "equation": "L-arginyl-glycine(out) = L-arginyl-glycine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79391", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79391" } ] }, { "id": "79395", "name": "", "equation": "L-histidyl-glycine(out) = L-histidyl-glycine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79395", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79395" } ] }, { "id": "79399", "name": "", "equation": "L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79399", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79399" } ] }, { "id": "79403", "name": "", "equation": "L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79403", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79403" } ] }, { 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"mapk-regulated corepressor-interacting protein 1", "type": "synonym", "evidence": [ { "id": "NP_001292004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292004" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992604, SAMN06143078 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU342287.1, DR424090.1, DR412522.1 and AJ744680.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001292004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292004" } ] }, { "annotation": "May play a role in the regulation of the epithelial-mesenchymal transition.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1#function" }, { "database": "UniProtKB", "id": "C9JLW8", "url": "https://www.uniprot.org/uniprotkb/C9JLW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCRIP1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1", "locus": { "chromosome": "18", "start_pos": 10545535, "end_pos": 10550405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029355", "url": "https://www.ensembl.org/id/ENSGALG00010029355" } ] } } ], "crossref": [ { "id": "Q5ZIU1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042814", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042814", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101749776", "url": "https://www.ncbi.nlm.nih.gov/gene/101749776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749776", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQNHERN", "url": "https://omabrowser.org/oma/group/PQNHERN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZIU1", "url": "https://www.orthodb.org/?gene=Q5ZIU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIU1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIU1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001292004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIU1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 96, "header": "sp|Q5ZIU1-1|MCRI1_CHICK Isoform 1 of Mapk-regulated corepressor-interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=Q5ZIU1-1" }, "isoforms": [ { "isoform_ac": "Q5ZIU1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1/entry#Q5ZIU1-1", "sequence": { "sequence": "MASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 96, "header": "sp|Q5ZIU1-1|MCRI1_CHICK Isoform 1 of Mapk-regulated corepressor-interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=Q5ZIU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:101749776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749776", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "C9JLW8-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "MCRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSSPVSRVVYNGKRTSSPRSPPSSSEIFTPAHEENVRFIYEAWQGVERDLRGQVPGGERGLVEEYVEKVPNPSLKTFKPIDLSDLKRRSTQDAKKS", "length": 97 }, "evidence": [ { "id": "Q5ZIU1", "url": "https://omabrowser.org/oma/group/Q5ZIU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3GX80-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "Mcrip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSSPVSRVVYNGKRNSSPRSPTNSSEIFTPAHEENVRFIYEAWQGVERDLRSQLSGGERGLVEEYVEKVPNPSLKTFKPIDLSDLKRRNTQDAKKS", "length": 97 }, "evidence": [ { "id": "Q5ZIU1", "url": "https://omabrowser.org/oma/group/Q5ZIU1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0P4B9-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "mcrip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSSSTPRMHTYKRTSSPRSPTNTGELFTPAHEENVRFIHDTWLCVLRDIKCPQNHERNDRGPQEYVEKNPNPNLHSFIPVDLSDLKKRNTQDSKKS", "length": 97 }, "evidence": [ { "id": "Q5ZIU1", "url": "https://omabrowser.org/oma/group/Q5ZIU1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UGS4-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "Mcrip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSSPVSRVVYNGKRNSSPRSPTNSSEIFTPAHEENVRFIYEAWQGVERDLRSQLSSGERCLVEEYVEKVPNPSLKTFKPIDLSDLKRRNTQDAKKS", "length": 97 }, "evidence": [ { "id": "Q5ZIU1", "url": "https://omabrowser.org/oma/group/Q5ZIU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of epithelial to mesenchymal transition", "id": "GO:0010717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010717", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZIU1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 96, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZIU1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZIU1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU1" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "PXDLS motif", "eco_id": "ECO_0000305", "start_pos": 79, "end_pos": 83, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZIW5-1", "uniprot_ac": "Q5ZIW5", "uniprot_id": "VAC14_CHICK", "mass": { "chemical_mass": 87823.0, "monoisotopic_mass": 87823.0 }, "refseq": { "ac": "NP_001025735", "name": "protein VAC14 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735" }, "gene_names": [ { "name": "VAC14", "type": "recommended", "evidence": [ { "id": "Q5ZIW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5" } ] }, { "name": "RCJMB04_23c3", "type": "synonym", "evidence": [ { "id": "Q5ZIW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5" } ] }, { "name": "VAC14", "type": "synonym", "evidence": [ { "id": "NP_001025735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735" } ] } ], "protein_names": [ { "name": "Protein VAC14 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZIW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5/entry#names_and_taxonomy" } ] }, { "name": "Vac14 homolog", "type": "synonym", "evidence": [ { "id": "NP_001025735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735" } ] }, { "name": "protein VAC14 homolog", "type": "synonym", "evidence": [ { "id": "NP_001025735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720669.1, SRR13267658.22461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000247.1. On Sep 23, 2021 this sequence version replaced NP_001025735.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735" } ] }, { "annotation": "Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZIW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5#function" }, { "database": "UniProtKB", "id": "Q08AM6", "url": "https://www.uniprot.org/uniprotkb/Q08AM6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZIW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VAC14", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5", "locus": { "chromosome": "11", "start_pos": 1722401, "end_pos": 1670855, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022868", "url": "https://www.ensembl.org/id/ENSGALG00010022868" } ] } } ], "crossref": [ { "id": "Q5ZIW5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZIW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "415678", "url": "https://www.ncbi.nlm.nih.gov/gene/415678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415678", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZIW5", "url": "https://www.orthodb.org/?gene=Q5ZIW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16023:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16023:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZIW5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZIW5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZIW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZIW5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAERDLAPLAPSVVRALNDKLYEKRKVAALEIEKLVREFVAQNNTSQVKHVILILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNQFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVALGEFLKEIKKNPSSVKFAEMANILVIHCQAADDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLVIPEDDEMDEAKQSITLSAEPNPEEPVSKPEAASTGSLDVSGDSSVSNASVCTVTSSERIQVTLNLDGIVQVLDCHLHDTSIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLRTLSDESDEVILKDLEVLAEIASSPAGQTEGYGPSEAAEPRPGQVELHVPIRNSQLSSSGPKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLETRGAFIIRQLCLLLNTENIFHSMADILLREEDLKFASTMVHTLNTILLTSSELFQLRNQLKDLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELMQSADGSRASASSRRPASSTIDYTELLQHFDKVQSKHLEVRHQRAGRAEQPERRVVL", "length": 780, "header": "sp|Q5ZIW5-1|VAC14_CHICK Isoform 1 of Protein VAC14 homolog OS=Gallus gallus OX=9031 GN=VAC14 PE=2 SV=1 CANONICAL=Q5ZIW5-1" }, "isoforms": [ { "isoform_ac": "Q5ZIW5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW5/entry#Q5ZIW5-1", "sequence": { "sequence": "MNAERDLAPLAPSVVRALNDKLYEKRKVAALEIEKLVREFVAQNNTSQVKHVILILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNQFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVALGEFLKEIKKNPSSVKFAEMANILVIHCQAADDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLVIPEDDEMDEAKQSITLSAEPNPEEPVSKPEAASTGSLDVSGDSSVSNASVCTVTSSERIQVTLNLDGIVQVLDCHLHDTSIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLRTLSDESDEVILKDLEVLAEIASSPAGQTEGYGPSEAAEPRPGQVELHVPIRNSQLSSSGPKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLETRGAFIIRQLCLLLNTENIFHSMADILLREEDLKFASTMVHTLNTILLTSSELFQLRNQLKDLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELMQSADGSRASASSRRPASSTIDYTELLQHFDKVQSKHLEVRHQRAGRAEQPERRVVL", "length": 780, "header": "sp|Q5ZIW5-1|VAC14_CHICK Isoform 1 of Protein VAC14 homolog OS=Gallus gallus OX=9031 GN=VAC14 PE=2 SV=1 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The reference sequence was derived from AJ720614.1. On Aug 8, 2005 this sequence version replaced XP_422731.1. Sequence Note: This sequence has been modified as follows: removed 29 bp suspected to be vector contamination from the 3' end.", "evidence": [ { "database": "RefSeq", "id": "NP_001026487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026487" } ] }, { "annotation": "Required for mRNA export from the nucleus to the cytoplasm. 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Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ20", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ20" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.", "journal": "Curr. 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026548" } ] }, { "name": "RCJMB04_20f16", "type": "synonym", "evidence": [ { "id": "Q5ZJ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65" } ] } ], "protein_names": [ { "name": "Protein FAM76A", "type": "recommended", "evidence": [ { "id": "Q5ZJ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65/entry#names_and_taxonomy" } ] }, { "name": "protein FAM76A", "type": "synonym", "evidence": [ { "id": "NP_001026548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026548" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720569.1, SRR13267659.4656.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Aug 8, 2005 this sequence version replaced XP_424036.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026548" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ65", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM76A", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65", "locus": { "chromosome": "23", "start_pos": 2459349, "end_pos": 2444214, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018339", "url": "https://www.ensembl.org/id/ENSGALG00010018339" } ] } } ], "crossref": [ { "id": "Q5ZJ65", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJ65", "database": "AlphaFoldDB", "categories": [] }, { "id": "426384", "url": "https://www.ncbi.nlm.nih.gov/gene/426384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426384", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426384", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJ65", "url": "https://www.orthodb.org/?gene=Q5ZJ65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJ65", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJ65", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJ65", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ65-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPIVKCTYCRTEFQQESKTNTICKKCAQNVKLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPHSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQCKHLSSSSRASLQEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKAKFDAISANGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADLQYQESQMRAKMNQMEKTHKEVMEQLQAKNRELLKQAAALSKGKKPEKSGAITSP", "length": 307, "header": "sp|Q5ZJ65-1|FA76A_CHICK Isoform 1 of Protein FAM76A OS=Gallus gallus OX=9031 GN=FAM76A PE=2 SV=1 CANONICAL=Q5ZJ65-1" }, "isoforms": [ { "isoform_ac": "Q5ZJ65-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65/entry#Q5ZJ65-1", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPIVKCTYCRTEFQQESKTNTICKKCAQNVKLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPHSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQCKHLSSSSRASLQEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKAKFDAISANGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADLQYQESQMRAKMNQMEKTHKEVMEQLQAKNRELLKQAAALSKGKKPEKSGAITSP", "length": 307, "header": "sp|Q5ZJ65-1|FA76A_CHICK Isoform 1 of Protein FAM76A OS=Gallus gallus OX=9031 GN=FAM76A PE=2 SV=1 CANONICAL=Q5ZJ65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ65", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426384", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426384", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ65", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ65", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJ65-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJ65-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJ65" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJ69-1", "uniprot_ac": "Q5ZJ69", "uniprot_id": "ARI5B_CHICK", "mass": { "chemical_mass": 132723.0, "monoisotopic_mass": 132723.0 }, "refseq": { "ac": "NP_001026391", "name": "AT-rich interactive domain-containing protein 5B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" }, "gene_names": [ { "name": "ARID5B", "type": "recommended", "evidence": [ { "id": "Q5ZJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69" } ] }, { "name": "ARID5B", "type": "synonym", "evidence": [ { "id": "NP_001026391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" } ] }, { "name": "RCJMB04_20e24", "type": "synonym", "evidence": [ { "id": "Q5ZJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69" } ] } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 5B", "type": "recommended", "evidence": [ { "id": "Q5ZJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69/entry#names_and_taxonomy" } ] }, { "name": "ARID domain-containing protein 5B", "type": "synonym", "evidence": [ { "id": "NP_001026391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" }, { "id": "Q5ZJ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69/entry#names_and_taxonomy" } ] }, { "name": "AT rich interactive domain 5B (MRF1-like)", "type": "synonym", "evidence": [ { "id": "NP_001026391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" } ] }, { "name": "AT-rich interactive domain-containing protein 5B", "type": "synonym", "evidence": [ { "id": "NP_001026391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720565.1, SRR13267654.150894.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000227.1. On Sep 23, 2021 this sequence version replaced NP_001026391.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391" } ] }, { "annotation": "Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ69", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ69", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARID5B", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69", "locus": { "chromosome": "6", "start_pos": 8955309, "end_pos": 9064178, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009502", "url": "https://www.ensembl.org/id/ENSGALG00010009502" } ] } } ], "crossref": [ { "id": "Q5ZJ69", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJ69", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423661", "url": "https://www.ncbi.nlm.nih.gov/gene/423661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423661", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423661", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJ69", "url": "https://www.orthodb.org/?gene=Q5ZJ69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJ69", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJ69", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJ69", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ69-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSALQWVGAPCGSHGPYVFYRAFRFQRRGGGRARVLSLGDFFFVRCRAEEPACIAELQLLWEERTSRQLLSSAKLYFLPEDTPQGRTSDHGEDEVIAVSEKVTVKLEDLAKWAQSDFSKWKCGFRAEPVKPMDVGKNGQKEALMRYRQSTLNSGLNFKDILKEKADLGEDDEDSNLLILSYPQYCRYRSMLKRIQDKPSSILTDQFVLALGGIAVTSKNPQIFYCRDTFDHPTLIENESICDEFAPNLKGRPRKKKPCPQRRDSLNGIKDSNNNSESKAVAKVKCEAKSALPKPKSNNSNCKKGSSEDKSKIAVGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPVKPRKQDNSSQEGEAKTKVSGTKRIKNENQKSKKEKDNAQKPQDASEVSSEQEKDQESADQKNFTEHPTAGETKQPNQGPPPLLPEAARPLPMEKIDVTENSSSSEKAKEEVPHLSSFPSLSMPPDEDTVLDATVTKRLHSSADTQEDTKPERRIHKAFTESLENEPPEMPFSTFPVQLPTQSDMEDDKLPEMADYIANCTVKVDQLGNEDIHNALKQTPKVLVVQNFDMFKEKELPGSMSDDSTFGYTPLLYSKGNPGIMSPLAKKKLLSQVSGAALSCSYPYGSPPPLISKKKLNSRDELSSSLSQGPHVPNSDPIAINRPSVIQHVQSFKSKEERKSINDVFKHDMLSKVDPQRCDFSQHCLSSLAESYVPKTDIQDCKDKMTEKRALQHSRVPTFLADFYSSPHLHNLFRHTEHHLNNEQTSKYLPRDMFRESENISTFTQHKHQEKLNLNYHPSLHQQEKKATVEASSDDQPTDLSLPKSIHKQTAKAPGPGLSHSSMAQQEGKGVSLFQAASSQAVSLDCNPKACRVSPMAMTAPKKHSELLHRSGKQQAQRLENLRKMEGMVHPIISRRMSPQNIGAARPLKRGLEELDKVISEKKVRAVSPLHLPKETSVKEKVPDAEGEGSKSLHGLHSGSVLESHKFPLSAPIFPGLYPGTLCTGLNNRLPPGYSHPLQYLKNQTVLSPLMQPLALHSLMVQRQFLTSPANSQQLYRHLATATPVGSSYGDLLHNSIYPLAAINPQAAFPPSQLSSVHPSTKL", "length": 1185, "header": "sp|Q5ZJ69-1|ARI5B_CHICK Isoform 1 of AT-rich interactive domain-containing protein 5B OS=Gallus gallus OX=9031 GN=ARID5B PE=2 SV=1 CANONICAL=Q5ZJ69-1" }, "isoforms": [ { "isoform_ac": "Q5ZJ69-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69/entry#Q5ZJ69-1", "sequence": { "sequence": 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"length": 1185, "header": "sp|Q5ZJ69-1|ARI5B_CHICK Isoform 1 of AT-rich interactive domain-containing protein 5B OS=Gallus gallus OX=9031 GN=ARID5B PE=2 SV=1 CANONICAL=Q5ZJ69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ69", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ69" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423661", "name": "", "url": 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"protein_names": [ { "name": "Protein CREG1", "type": "recommended", "evidence": [ { "id": "Q5ZJ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ73/entry#names_and_taxonomy" } ] }, { "name": "Protein CREG1", "type": "synonym", "evidence": [ { "id": "NP_001291993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291993" } ] }, { "name": "protein CREG1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001291993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291993" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267653.21605.1, SRR13267655.16439.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000019.1. On Sep 23, 2021 this sequence version replaced NP_001291993.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001291993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291993" } ] }, { "annotation": "May contribute to the transcriptional control of cell growth and differentiation.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ73", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ73#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ73", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ73" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CREG1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ73", "locus": { "chromosome": "1", "start_pos": 91777369, "end_pos": 91771951, "strand": "-", "evidence": [ { "database": "Ensembl Gene", 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"https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419356", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ75", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ75" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ75", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { 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The reference sequence was derived from JAENSK010000308.1. 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"MDFNVKKLASDAGVFFSRAMQFTEEKLGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMTEAANDFGPGTPYGKTLIKVGETQRRLGAAERDFIHSASINFLTPLRNFLEGDWRTISKERRILQNRRLDLDACKARLKKAKAAEAKAAAVPDFQETRPRNYVLSASASALWSDEVEKAEHELRLTQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTNYYAQCYQYMLDLQKQLGRFSGTFVGNAESTSPPPAAASPPAVAATTLPAVPTIPVVPTIVGVPNTVAESVLNPNEVKPPASGTRKARVLYDYEAADSTELALLADEMITVYSLPGMDPDWLIGERGNQKGKVPVTYLELLS", "length": 403, "header": "sp|Q5ZJ81-1|SHLB2_CHICK Isoform 1 of Endophilin-B2 OS=Gallus gallus OX=9031 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q5ZJ81-1" }, "isoforms": [ { "isoform_ac": "Q5ZJ81-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ81/entry#Q5ZJ81-1", "sequence": { "sequence": "MDFNVKKLASDAGVFFSRAMQFTEEKLGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMTEAANDFGPGTPYGKTLIKVGETQRRLGAAERDFIHSASINFLTPLRNFLEGDWRTISKERRILQNRRLDLDACKARLKKAKAAEAKAAAVPDFQETRPRNYVLSASASALWSDEVEKAEHELRLTQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTNYYAQCYQYMLDLQKQLGRFSGTFVGNAESTSPPPAAASPPAVAATTLPAVPTIPVVPTIVGVPNTVAESVLNPNEVKPPASGTRKARVLYDYEAADSTELALLADEMITVYSLPGMDPDWLIGERGNQKGKVPVTYLELLS", "length": 403, "header": "sp|Q5ZJ81-1|SHLB2_CHICK Isoform 1 of Endophilin-B2 OS=Gallus gallus OX=9031 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q5ZJ81-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, 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"database": "PROSITE", "url": "https://prosite.expasy.org/PRU00192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000255", "start_pos": 343, "end_pos": 403, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"evidence": [ { "id": "Q5ZJ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85/entry#names_and_taxonomy" } ] }, { "name": "U4/U6 small nuclear ribonucleoprotein Prp3 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026561" } ] }, { "name": "U4/U6 small nuclear ribonucleoprotein Prp3", "type": "synonym", "evidence": [ { "id": "NP_001026561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026561" } ] }, { "name": "pre-mRNA-splicing factor 3", "type": "synonym", "evidence": [ { "id": "NP_001026561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026561" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720549.1, HAEK01030771.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000352.1. On Nov 12, 2021 this sequence version replaced NP_001026561.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026561" } ] }, { "annotation": "Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85#function" }, { "database": "UniProtKB", "id": "O43395", "url": "https://www.uniprot.org/uniprotkb/O43395#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRPF3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85", "locus": { "chromosome": "25", "start_pos": 2292416, "end_pos": 2303254, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028606", "url": "https://www.ensembl.org/id/ENSGALG00010028606" } ] } } ], "crossref": [ { "id": "Q5ZJ85", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJ85", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd24162", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24162", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426667", "url": "https://www.ncbi.nlm.nih.gov/gene/426667", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426667", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426667", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJ85", "url": "https://www.orthodb.org/?gene=Q5ZJ85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14212:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14212:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJ85", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJ85", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJ85-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTLRFVDKLFEAVEEGRSSRHSKSNSDRNRKRELKDVFGDDSEVSKESSGVKKRRIPRFEEVEDEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKISSSSQSERLPIGNTVQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTYFDLRVSITPAQRQKRTFKFHEKGKFEKIAQRLRTKAQLKKLQAEISQAARKTGIHTSTKLALITPKKELKEGEIPEIEWWDSYIIPNGLDLKGGTSSKKDEYFGITNLVEHPAQLNPPVDSDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKAKKIKKLKEDVSQGVHIAVYRVRNLSNPAKKFKIEANAGQLYLTGVVVLHKDVNVVVVEGGPKAQKKFKRLMLHRIKWDEQTSNTKGEDDDESDEESVKKTNKCSLVWEGTAKDRSFGEMKFKQCPTENMAREHFKKHGAEHYWDLALSESVLESTD", "length": 684, "header": "sp|Q5ZJ85-1|PRPF3_CHICK Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp3 OS=Gallus gallus OX=9031 GN=PRPF3 PE=2 SV=1 CANONICAL=Q5ZJ85-1" }, "isoforms": [ { "isoform_ac": "Q5ZJ85-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85/entry#Q5ZJ85-1", "sequence": { "sequence": "MSLSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTLRFVDKLFEAVEEGRSSRHSKSNSDRNRKRELKDVFGDDSEVSKESSGVKKRRIPRFEEVEDEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKISSSSQSERLPIGNTVQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTYFDLRVSITPAQRQKRTFKFHEKGKFEKIAQRLRTKAQLKKLQAEISQAARKTGIHTSTKLALITPKKELKEGEIPEIEWWDSYIIPNGLDLKGGTSSKKDEYFGITNLVEHPAQLNPPVDSDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKAKKIKKLKEDVSQGVHIAVYRVRNLSNPAKKFKIEANAGQLYLTGVVVLHKDVNVVVVEGGPKAQKKFKRLMLHRIKWDEQTSNTKGEDDDESDEESVKKTNKCSLVWEGTAKDRSFGEMKFKQCPTENMAREHFKKHGAEHYWDLALSESVLESTD", "length": 684, "header": "sp|Q5ZJ85-1|PRPF3_CHICK Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp3 OS=Gallus gallus OX=9031 GN=PRPF3 PE=2 SV=1 CANONICAL=Q5ZJ85-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426667", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426667", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJ85", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJ85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 684, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJ85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJ85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ85" }, { "id": "PRU00627", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00627" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWI", "eco_id": "ECO_0000255", "start_pos": 1, "end_pos": 87, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 318 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 551, "end_pos": 553 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJA4-1", "uniprot_ac": "Q5ZJA4", "uniprot_id": "ARP5_CHICK", "mass": { "chemical_mass": 69354.0, "monoisotopic_mass": 69354.0 }, "refseq": { "ac": "NP_001008446", "name": "actin-related protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008446" }, "gene_names": [ { "name": "ACTR5", "type": "recommended", "evidence": [ { "id": "Q5ZJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4" } ] }, { "name": "ACTR5", "type": "synonym", "evidence": [ { "id": "NP_001008446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008446" } ] }, { "name": "RCJMB04_19k24", "type": "synonym", "evidence": [ { "id": "Q5ZJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4" } ] } ], "protein_names": [ { "name": "Actin-related protein 5", "type": "recommended", "evidence": [ { "id": "Q5ZJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein 5", "type": "synonym", "evidence": [ { "id": "NP_001008446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008446" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720530.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000328.1. On Sep 23, 2021 this sequence version replaced NP_001008446.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008446" } ] }, { "annotation": "Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJA4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACTR5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4", "locus": { "chromosome": "20", "start_pos": 4105946, "end_pos": 4092117, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023731", "url": "https://www.ensembl.org/id/ENSGALG00010023731" } ] } } ], "crossref": [ { "id": "Q5ZJA4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003559", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003559", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419169", "url": "https://www.ncbi.nlm.nih.gov/gene/419169", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419169", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419169", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJA4", "url": "https://www.orthodb.org/?gene=Q5ZJA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJA4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJA4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJA4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJA4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGRVFAFRDARWAPDPVLAPSAAVRSPQPVPLVIDNGSFQTRAGWAAADPSVPAEPLLRFRSLAARSRGARGGAGAETQVGNDLGSPEPLRWLLRSPFDRNVPVQLELQELLFDHVFQRLGVASQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYQVPKVSYGVDSLYSFYHNRRQNWPCSGLVISSGYQCTHILPVLEGRLDAKNCKRINLGGCQAAVYLQRLLQLKYPGHFAAITLSRMEEILHEHSYIAEDYTEELQKWRSPEYYENNVHKMQLPFSNKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALVELNMDSAEELQSYINKLSLAIEQTKQKILQAEVNIEVDIVDSKPETPDLDPLSSEQSLEDVESINEFEPLFAEEQPEAEKPVAAVQPVFNLAEYHQLFLGTERIRAPEIIFQPSLIGEDQTGIAETMQYVLERYSKEQQALLVQNVFLTGGNAMYPGLKARVQKELLEMRPFQSSFQVHLASSPTLDAWYGARDWAVEHMTREEGWITRKDYEEKGGEYLKEHCASNVYVPIRLPKQAPRTTEALAPSRALAAGTGNPCEQA", "length": 611, "header": "sp|Q5ZJA4-1|ARP5_CHICK Isoform 1 of Actin-related protein 5 OS=Gallus gallus OX=9031 GN=ACTR5 PE=2 SV=1 CANONICAL=Q5ZJA4-1" }, "isoforms": [ { "isoform_ac": "Q5ZJA4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJA4/entry#Q5ZJA4-1", "sequence": { "sequence": 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been subject to final NCBI review. The reference sequence was derived from JAENSK010000044.1. On Sep 23, 2021 this sequence version replaced NP_001006348.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006348" } ] }, { "annotation": "Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. 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"MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDYAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLCEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI", "length": 405, "header": "sp|Q5ZJC8-1|MTEF3_CHICK Isoform 1 of Transcription termination factor 3, mitochondrial OS=Gallus gallus OX=9031 GN=MTERF3 PE=2 SV=1 CANONICAL=Q5ZJC8-1" }, "isoforms": [ { "isoform_ac": "Q5ZJC8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8/entry#Q5ZJC8-1", "sequence": { "sequence": "MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDYAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLCEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI", "length": 405, "header": "sp|Q5ZJC8-1|MTEF3_CHICK Isoform 1 of Transcription termination factor 3, mitochondrial OS=Gallus gallus OX=9031 GN=MTERF3 PE=2 SV=1 CANONICAL=Q5ZJC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:420237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420237", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" }, { "name": "mitochondrial ribosome assembly", "id": "GO:0061668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061668", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" }, { "name": "regulation of mitochondrial transcription", "id": "GO:1903108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903108", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJC8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJC8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJC8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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The reference sequence was derived from AJ720490.1. On Dec 15, 2004 this sequence version replaced XP_415316.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007842" } ] }, { "annotation": "Positively regulates hepatic SREBP signaling pathway by modulating the proper localization of SCAP (SREBP cleavage-activating protein) to the endoplasmic reticulum, thereby controlling the level of functional SCAP.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4#function" }, { "database": "UniProtKB", "id": "Q9H741", "url": "https://www.uniprot.org/uniprotkb/Q9H741#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPRING", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4", "locus": {} } ], "crossref": [ { "id": "Q5ZJE4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031821", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417026", "url": "https://www.ncbi.nlm.nih.gov/gene/417026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417026", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417026", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNTTSHC", "url": "https://omabrowser.org/oma/group/CNTTSHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJE4", "url": "https://www.orthodb.org/?gene=Q5ZJE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13481:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13481:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJE4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJE4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJE4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPCGAVLWRRLLRKRWVLGVVFGLSLVYFLSSTFKQEERTVRDRNLLQVQEHEQPILWKEQFSSGNGSHLSNQCRNSVQGKLLITDELGYICERKDLLVNGCCNVNVPSTKLYSCDSCLPNGCCSVYEYCVSCCLQPSKQHLLERFLNRAAMAFQNLFMAVEDRFELCLAKCRTSSQSVQHENTYRDPIAKYCYGEYPPELLPV", "length": 205, "header": "sp|Q5ZJE4-1|SPRNG_CHICK Isoform 1 of SREBP regulating gene protein OS=Gallus gallus OX=9031 GN=SPRING PE=2 SV=1 CANONICAL=Q5ZJE4-1" }, "isoforms": [ { "isoform_ac": "Q5ZJE4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4/entry#Q5ZJE4-1", "sequence": { "sequence": "MVPCGAVLWRRLLRKRWVLGVVFGLSLVYFLSSTFKQEERTVRDRNLLQVQEHEQPILWKEQFSSGNGSHLSNQCRNSVQGKLLITDELGYICERKDLLVNGCCNVNVPSTKLYSCDSCLPNGCCSVYEYCVSCCLQPSKQHLLERFLNRAAMAFQNLFMAVEDRFELCLAKCRTSSQSVQHENTYRDPIAKYCYGEYPPELLPV", "length": 205, "header": "sp|Q5ZJE4-1|SPRNG_CHICK Isoform 1 of SREBP regulating gene protein OS=Gallus gallus OX=9031 GN=SPRING PE=2 SV=1 CANONICAL=Q5ZJE4-1" }, "locus": { "chromosome": "15", "start_pos": 11444117, "end_pos": 11440970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001000.1", "url": "https://www.ensembl.org/id/ENSGALT00010001000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000528.1", "url": "https://www.ensembl.org/id/ENSGALP00010000528.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 67, "start_aa": "Asn", "end_pos": 67, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn67", "evidence": [ { "id": "Q5ZJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417026", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480VC18-1", "protein_name": "SREBP regulating gene protein", "gene_name": "SPRING1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLTSTFKQEERAVRDRNLLQVQDHDQPIPWKVQFNLGNSSRPSNQCRNSIQGKHLITDELGYVCERKDLLVNGCCNVNVPGTKQYCCDGCLSNGCCSAYEYCVSCCLQPSKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 205 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FW99-1", "protein_name": "SREBP regulating gene protein", "gene_name": "Spring1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLNLAALLWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAVRDRNLLQIQDREQPIPWKVQFNLGNSSRPSNQCRNSVQGKHLITDELGEASPGSQDVHLWLSGYVCERKDLLANGCCDVTVPSTKQYCCDGCLANGCCEAYEHCVSCCLQPSKQLLLERFLNRAAMAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 220 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZTN6-1", "protein_name": "SREBP regulating gene protein", "gene_name": "Spring1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNLAALLWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAIRDRNLLQVQDREQPIPWKVQFNLGNSSRPSNQCRNSVQGKHLITDELGYVCERKDLLANGCCDVSVPSTKQYCCNGCLANGCCEAYEYCVSCCLQPSKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 205 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17QN8-1", "protein_name": "SREBP regulating gene protein", "gene_name": "SPRING", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLTSTFKQEERAVRDRNLLQVQDHDQPIPWKVQFNLGNSSRPSNQCRNSIQGKHLITDELGYVCERRDLLVNGCCNVNVPGTKQYCCDGCLSSGCCSAYEYCVSCCLQPNKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 205 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BTG6-1", "protein_name": "SREBP regulating gene protein", "gene_name": "Spring1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNLAALLWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAVRDRNLLQVQDREQPIPWKVQFNLGNSSRPSNQCRNSVQGKHLLTDELGYVCERKDLLANGCCDVSVPSTKQYCCDGCLANGCCEAYEYCVSCCLQPSKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 205 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H741-1", "protein_name": "SREBP regulating gene protein", "gene_name": "SPRING1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAVRDRNLLQVHDHNQPIPWKVQFNLGNSSRPSNQCRNSIQGKHLITDELGYVCERKDLLVNGCCNVNVPSTKQYCCDGCWPNGCCSAYEYCVSCCLQPNKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA", "length": 205 }, "evidence": [ { "id": "Q5ZJE4", "url": "https://omabrowser.org/oma/group/Q5ZJE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of SREBP signaling pathway", "id": "GO:2000640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000640", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJE4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJE4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 205, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJE4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJE4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 67 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJG3-1", "uniprot_ac": "Q5ZJG3", "uniprot_id": "BT3L4_CHICK", "mass": { "chemical_mass": 17232.0, "monoisotopic_mass": 17232.0 }, "refseq": {}, "gene_names": [ { "name": "BTF3L4", "type": "recommended", "evidence": [ { "id": "Q5ZJG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG3" } ] }, { "name": 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"url": "https://www.uniprot.org/uniprotkb/Q5ZJG3", "locus": { "chromosome": "8", "start_pos": 23974385, "end_pos": 23947073, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024840", "url": "https://www.ensembl.org/id/ENSGALG00010024840" } ] } } ], "crossref": [ { "id": "Q5ZJG3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424638", "url": "https://www.ncbi.nlm.nih.gov/gene/424638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424638", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJG3", "url": "https://www.orthodb.org/?gene=Q5ZJG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJG3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJG3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZJG3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJG3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKSEDIDEEDDDVPDLAENFDEASKNEAN", "length": 158, "header": "sp|Q5ZJG3-1|BT3L4_CHICK Isoform 1 of Transcription factor BTF3 homolog 4 OS=Gallus gallus OX=9031 GN=BTF3L4 PE=2 SV=1 CANONICAL=Q5ZJG3-1" }, "isoforms": [ { "isoform_ac": "Q5ZJG3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG3/entry#Q5ZJG3-1", "sequence": { "sequence": "MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKSEDIDEEDDDVPDLAENFDEASKNEAN", "length": 158, "header": "sp|Q5ZJG3-1|BT3L4_CHICK Isoform 1 of Transcription factor BTF3 homolog 4 OS=Gallus gallus OX=9031 GN=BTF3L4 PE=2 SV=1 CANONICAL=Q5ZJG3-1" }, "locus": {} } ], "glycosylation": 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The reference sequence was derived from JAENSK010000247.1. On Sep 23, 2021 this sequence version replaced NP_001005837.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001005837", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005837" } ] }, { "annotation": "May catalyze the metabolism of steroid hormones and thus play an important role in sex differentiation, the emergence and maintenance of the secondary sexual characters, and the regulation of endocrine.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSDL1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG8", "locus": { 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"database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005837", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005837", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJG8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVDRFNLLYREISRSCSVYIEALAIVGAWYTVRKCLTLVFNTYSMIRLHALPKLVGEIDIVKRYGRWAVVTGSTDGIGKAYAEELAKRGVNIILISRSKEKLEAVSRSISETYKVETDFIVADFSKGREAYQAIKEGLKDREIGILVNNVGLFYTYPDYFTNLSEDMLWDMINVNIASANMMVHIVLPGMVEKRKGAIVNVSSASCCQPTPMLTTYGASKAYLDYFSRALYYEYASKGIFVQSLTPFVIATRMVSCSRVTSKRSFFFPSAEEYASHAISTLGLSKRTPGYWKHSIEFTLGERLPEWIWAWFAQYFCRIIRKEALTHKAK", "length": 331, "header": "sp|Q5ZJG8-1|HSDL1_CHICK Isoform 1 of Hydroxysteroid dehydrogenase-like protein 1 OS=Gallus gallus OX=9031 GN=HSDL1 PE=2 SV=1 CANONICAL=Q5ZJG8-1" }, "isoforms": [ { 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"https://www.uniprot.org/uniprotkb/Q5ZJH7" } ] } ], "protein_names": [ { "name": "Protein CNPPD1", "type": "recommended", "evidence": [ { "id": "Q5ZJH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7/entry#names_and_taxonomy" } ] }, { "name": "protein CNPPD1", "type": "synonym", "evidence": [ { "id": "NP_001034396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034396" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720457.1, HAEK01020389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Jan 31, 2006 this sequence version replaced XP_422051.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001034396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034396" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNPPD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7", "locus": { "chromosome": "7", "start_pos": 21883574, "end_pos": 21877558, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021489", "url": "https://www.ensembl.org/id/ENSGALG00010021489" } ] } } ], "crossref": [ { "id": "Q5ZJH7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011343", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011343", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424204", "url": "https://www.ncbi.nlm.nih.gov/gene/424204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424204", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPRVENQ", "url": "https://omabrowser.org/oma/group/WPRVENQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJH7", "url": "https://www.orthodb.org/?gene=Q5ZJH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15615:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15615:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJH7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJH7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001034396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJH7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLNGFLLDEEGAFSLSGFQEFTFLPRHQQLSERVRKRLYYGWDKECTLDNLSSPVADIAVELLQKVAPSPIRRLQKKYVSHVSREACISPCSMMLALVYIERLRHRNPEYLQQISSSDLFLISMMVASKYLYDEGEEEEVFNDEWGAAGKVDVQTMNTLEMNFLSAIDWSLYTDPRELFEVLSWLEGRVAEKQGMWRGWFTYTDLCVLMEQSMWQQALGHFYQQVVKLACLLGVVYLTGFAAVFTSIAVVHRAVCTRSTSITALRPALIPVESGCQLGAQPALAPEQPQPKLPDVSPPSSTHCLGENETAEELRRGGVTATALYLWGSVMTALSYVKAPDIALHKSPLQAPLRKVPTACERSNRTAPVTAPNQPGPFGLAVLLAPPALHCHTCSAAARPTWDATPNHRKDWLDPLGLRQCFLHAALDLGRIKSFIFPS", "length": 439, "header": "sp|Q5ZJH7-1|CNPD1_CHICK Isoform 1 of Protein CNPPD1 OS=Gallus gallus OX=9031 GN=CNPPD1 PE=2 SV=1 CANONICAL=Q5ZJH7-1" }, "isoforms": [ { "isoform_ac": "Q5ZJH7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7/entry#Q5ZJH7-1", "sequence": { "sequence": "MDLNGFLLDEEGAFSLSGFQEFTFLPRHQQLSERVRKRLYYGWDKECTLDNLSSPVADIAVELLQKVAPSPIRRLQKKYVSHVSREACISPCSMMLALVYIERLRHRNPEYLQQISSSDLFLISMMVASKYLYDEGEEEEVFNDEWGAAGKVDVQTMNTLEMNFLSAIDWSLYTDPRELFEVLSWLEGRVAEKQGMWRGWFTYTDLCVLMEQSMWQQALGHFYQQVVKLACLLGVVYLTGFAAVFTSIAVVHRAVCTRSTSITALRPALIPVESGCQLGAQPALAPEQPQPKLPDVSPPSSTHCLGENETAEELRRGGVTATALYLWGSVMTALSYVKAPDIALHKSPLQAPLRKVPTACERSNRTAPVTAPNQPGPFGLAVLLAPPALHCHTCSAAARPTWDATPNHRKDWLDPLGLRQCFLHAALDLGRIKSFIFPS", "length": 439, "header": "sp|Q5ZJH7-1|CNPD1_CHICK Isoform 1 of Protein CNPPD1 OS=Gallus gallus OX=9031 GN=CNPPD1 PE=2 SV=1 CANONICAL=Q5ZJH7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424204", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJH7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJH7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJH7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJH7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJJ1-1", "uniprot_ac": "Q5ZJJ1", "uniprot_id": "ZC11A_CHICK", "mass": { "chemical_mass": 79074.0, "monoisotopic_mass": 79074.0 }, "refseq": { "ac": "NP_001026201", "name": "zinc finger CCCH domain-containing protein 11A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" }, "gene_names": [ { "name": "ZC3H11A", "type": "recommended", "evidence": [ { "id": "Q5ZJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ] }, { "name": "RCJMB04_17l7", "type": "synonym", "evidence": [ { "id": "Q5ZJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ] }, { "name": "ZC3H11A", "type": "synonym", "evidence": [ { "id": "NP_001026201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" } ] }, { "name": "ZC3H11B", "type": "synonym", "evidence": [ { "id": "NP_001026201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 11A", "type": "recommended", "evidence": [ { "id": "Q5ZJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 11A", "type": "synonym", "evidence": [ { "id": "NP_001026201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" } ] }, { "name": "zinc finger CCCH-type containing 11B pseudogene", "type": "synonym", "evidence": [ { "id": "NP_001026201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720443.1, SRR13267649.38102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000356.1. On Aug 8, 2005 this sequence version replaced XP_419252.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026201", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201" } ] }, { "annotation": "Through its association with TREX complex components, may participate in the export and post-transcriptional coordination of selected mRNA transcripts. Binds RNA.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1#function" }, { "database": "UniProtKB", "id": "O75152", "url": "https://www.uniprot.org/uniprotkb/O75152#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H11A", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1", "locus": { "chromosome": "26", "start_pos": 532999, "end_pos": 518101, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025892", "url": "https://www.ensembl.org/id/ENSGALG00010025892" } ] } } ], "crossref": [ { "id": "Q5ZJJ1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "421172", "url": "https://www.ncbi.nlm.nih.gov/gene/421172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421172", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVRPSVM", "url": "https://omabrowser.org/oma/group/NVRPSVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJJ1", "url": "https://www.orthodb.org/?gene=Q5ZJJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15725:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15725:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJJ1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJJ1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026201", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJJ1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKQGDDCYFYFYSTCNKGDNCPFRHCEAALGNETICTLWKEGRCFRNVCRFRHMEIDKKRSEIPCFWENQPGGCQKSNCAFHHTKGRYVDGLFLPPSKTTLPSPPESADDDLKAAQITLQQNKLSVQSNPSPQLRGVMKVENSENVPSPTHPPVVINAADDDEDDDDQLSEEGEETKTPVQQPAEENHNGLRIISTRKSNADTKQDDSLNFGIKTLEEIKLKKQKEKTKKQSEGPSGVPAHPLQSRTVPVPEKENVRTVVRTVTLSAKQGEEPVIRLNIAEKPGKRKGSVADVSGLPLKRSLAERLGRKIEVDKAPRREKGAKPAGEIHVKTLEEIRLERANQRGETLTAPQAEVCCKVEDPSSGVRPPPAVRIKTFSEALAERKQRRLEEEKQKLEEFLTEKRAEGERKKQRILPPSVPGKVKLEEPTRKIKPLEEVHIKTLEEIKQEKALRMQQSGENVPAPAAQPGPAPAGRKLLRITKLAAPGKEEKKTVELSRASPKAVSAPAEPSNQSAPNSKAQVKSLEGTVKEKLQLRQPEKLKKEVAAVPSATEETVKAKCKVCVKPSDSKASTPTKRALKRKAAEISPSAVAAVKPLSSTETEEPPAKKAALTAAPALPEDSLLTKPGVEKPPSSLELQLGSQADSVEQSGDSSSASASSQSVAKAQQLSSTGAGKAPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "length": 723, "header": "sp|Q5ZJJ1-1|ZC11A_CHICK Isoform 1 of Zinc finger CCCH domain-containing protein 11A OS=Gallus gallus OX=9031 GN=ZC3H11A PE=2 SV=1 CANONICAL=Q5ZJJ1-1" }, "isoforms": [ { "isoform_ac": "Q5ZJJ1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1/entry#Q5ZJJ1-1", "sequence": { "sequence": "MSKQGDDCYFYFYSTCNKGDNCPFRHCEAALGNETICTLWKEGRCFRNVCRFRHMEIDKKRSEIPCFWENQPGGCQKSNCAFHHTKGRYVDGLFLPPSKTTLPSPPESADDDLKAAQITLQQNKLSVQSNPSPQLRGVMKVENSENVPSPTHPPVVINAADDDEDDDDQLSEEGEETKTPVQQPAEENHNGLRIISTRKSNADTKQDDSLNFGIKTLEEIKLKKQKEKTKKQSEGPSGVPAHPLQSRTVPVPEKENVRTVVRTVTLSAKQGEEPVIRLNIAEKPGKRKGSVADVSGLPLKRSLAERLGRKIEVDKAPRREKGAKPAGEIHVKTLEEIRLERANQRGETLTAPQAEVCCKVEDPSSGVRPPPAVRIKTFSEALAERKQRRLEEEKQKLEEFLTEKRAEGERKKQRILPPSVPGKVKLEEPTRKIKPLEEVHIKTLEEIKQEKALRMQQSGENVPAPAAQPGPAPAGRKLLRITKLAAPGKEEKKTVELSRASPKAVSAPAEPSNQSAPNSKAQVKSLEGTVKEKLQLRQPEKLKKEVAAVPSATEETVKAKCKVCVKPSDSKASTPTKRALKRKAAEISPSAVAAVKPLSSTETEEPPAKKAALTAAPALPEDSLLTKPGVEKPPSSLELQLGSQADSVEQSGDSSSASASSQSVAKAQQLSSTGAGKAPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "length": 723, "header": "sp|Q5ZJJ1-1|ZC11A_CHICK Isoform 1 of Zinc finger CCCH domain-containing protein 11A OS=Gallus gallus OX=9031 GN=ZC3H11A PE=2 SV=1 CANONICAL=Q5ZJJ1-1" }, "locus": { "chromosome": "26", "start_pos": 531564, "end_pos": 522438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063115.1", "url": "https://www.ensembl.org/id/ENSGALT00010063115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038961.1", "url": "https://www.ensembl.org/id/ENSGALP00010038961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421172", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BGM4-1", "protein_name": "Zinc finger CCCH domain-containing protein 11A isoform X1", "gene_name": "zc3h11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLQGDDCYFFYYSTCTKGDSCPFRHCEAAMGSETVCNLWQEQRCFRNVCKFRHMEIDKNRKEIACYWENQPAGCQKPHCAFHHEKPRIINGNYLAPDKGQVARKDNEEAPLEEKVNQVPAPSANPTNPQLRGVKRTETQENVPSPTHPPVVINPVDDDDEDDQFSEEGDESLGVSPRKLVSSKHDSLDFGIQTLEEIRLRKALMSNLKKARQSTVQGLAQISRPTVEKENIQSLSRLEVNNVKIDSSGKEVGKRRIADRLGKRILERDVPGEEGPPLKRSLAERLGGVVESSTDVLTKKSHKPVHERLGLTTDMSSGDSEPKSSGDIRIKTLEEIRQEKAAKNLSKSKVVRVVKEVPQKEISPSRKSVKPVAGPQVKTFSEILHEKKRKMQEKKEQEINKADKSPERSEEPSSARAANKTTVTTGEVRVKTLEEIRREKAARMQTQLGETTDNKTPTSSEAELSGPSKRRILRINKTSPAAVTQTKPDASEKKPEPATEANGKIEPSSEVVKVKTFEEIMREKKLRKLQEEQVTSSNQTDVGASASPPAPEPSVQPQTTVRQRITFKAKPSPPVSDAVVIEKSSPERSEDSTPSTNTPKPSTSPVRPVRIAEGIVTPAETKVRPKVNVKPSVVKPAAPSVQKRKAAKVHSAVAEVKPLNTTCQTPSSPVMPNKRLKMASPTSKKVVQSDTQQVPSNIENIQMMPVSCSEPASTTSVETVVVPHSPVIKTPSMQRSRRCSTTSGRPPVVTSSSMDDFEDLLDEFTDDRLEDELELDSGKGEDDLLLELSEMIDS", "length": 794 }, "evidence": [ { "id": "Q5ZJJ1", "url": "https://omabrowser.org/oma/group/Q5ZJJ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S6B2-1", "protein_name": "C3H1-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPNQGEDCYFFFYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPMGCQKLNCAFHHNRGRYVDGLFLPPSKTVLPTVPESPEEEVKASQLTVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVASARKPGVNLKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLQPQPVPGPEKENVRTVVRTVTLSNKQGEEPLVRLSLTERLGKRKFSVGGDSDPPLKRSLAQRLGKKVEAPEINTDKTPKKVQVSKSLKERLGVSAGPDSEGATERVTKVGEIRVKTLEEILLERASQKRGELQTKLKTEGPSKVDDSTSGTRTSSTIRIKTFSEVLAEKKHRQQEAERQKSKKDVTCIKLKTDNDTKKTVVLPPVVASRGQSEEPAGRAKSMQEVHIKTLEEIKMEKALRVQQSSESSTSSQPQPEATPGARRFLRITKKTGIQEEKKLQEENEVASQSGVTRTEAKEASDETTGVGITKIQVKRCETGREKHVQKLPDRSTLQKEKSVLTPLRGDLDSGNTQLAEKPVLATVPGTTRHLTKRLPTKSSQKAEVETSGIGDSMLNVKCAAQALDKRGKAKPKVNVKPSVVKVVSSPKLAPKRKAAEVHPAVIAAVKPLSSSTVLQESPAKKAAVAVVPLLSEDKSVPVPETEKPRDSFVLPPTHSSSDLSPPEASGPSSSQMTTKTRRLSSTSTGKPPLSMEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "length": 816 }, "evidence": [ { "id": "Q5ZJJ1", "url": "https://omabrowser.org/oma/group/Q5ZJJ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75152-1", "protein_name": "Zinc finger CCCH domain-containing protein 11A", "gene_name": "ZC3H11A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSKTVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFSAGGDSDPPLKRSLAQRLGKKVEAPETNIDKTPKKAQVSKSLKERLGMSADPDNEDATDKVNKVGEIHVKTLEEILLERASQKRGELQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEKKHRQQEAERQKSKKDTTCIKLKIDSEIKKTVVLPPIVASRGQSEEPAGKTKSMQEVHIKTLEEIKLEKALRVQQSSESSTSSPSQHEATPGARRLLRITKRTGMKEEKNLQEGNEVDSQSSIRTEAKEASGETTGVDITKIQVKRCETMREKHMQKQQEREKSVLTPLRGDVASCNTQVAEKPVLTAVPGITRHLTKRLPTKSSQKVEVETSGIGDSLLNVKCAAQTLEKRGKAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKPLSSSSVLQEPPAKKAAVAVVPLVSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVSGPSSSQMSMKTRRLSSASTGKPPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "length": 810 }, "evidence": [ { "id": "Q5ZJJ1", "url": "https://omabrowser.org/oma/group/Q5ZJJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NZF1-1", "protein_name": "Zinc finger CCCH domain-containing protein 11A", "gene_name": "Zc3h11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPNQGEDCYFYFYSTCAKGDSCPFRHCEAALGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPVGCQKLNCAFHHTRSRYVDGLFLPPSKTVLPTVPESQEEEVKTSQLTVQQSKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDESKTPALQPSPDVHNGLRVASARKPGVSLKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSVLQQPQPNPGPEKENVRTVVRMVTLSSKPEEPLVRLSLSERLGKRKLSVGGDSDPPLKRSLAQRLGKKVESPETNIDKAPKKERGHKAGEIHVKTLEEILLERASQKRGELQTKLKAEEPSGADDSPSGTKSSSSVRIKTFSEVLAEKKHRQQEMERQKSKKDTSCLTLTDDTEMKKTVSLPTVAVSKGQPEEPAGRARSMQEVHIKTLEEIKLEKALRVQQSSESSGNSRPQAEAAPGTKRLLRITKRAGVKEEKKCGLEDSGDPPQSSVTKMEANETSDETISDPTKLAVNRCDTVKEKHTQRLQERGASQKEKAALSSVRGDEASSYTRVAGKPVLTAVSGVTRHLAKRLPVESSQKGEVETSGIGDSILNVKCAAQTLEKRSKVKPKVNVKPSVVKVVSAPKLAPKRKAVEMHSAVIAAVKPLSSSSVLQESPTKKAAVAVVPLLSEDKPVTMSETENPKDSSVLSSAQAASEPLLPEGSGPSSSQTATKPRRLSSASTGKPPLSVEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "length": 792 }, "evidence": [ { "id": "Q5ZJJ1", "url": "https://omabrowser.org/oma/group/Q5ZJJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJJ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 723, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJJ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJJ1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 33, "end_pos": 35 }, { "start_pos": 513, "end_pos": 515 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJJ9-1", "uniprot_ac": "Q5ZJJ9", "uniprot_id": "OSTF1_CHICK", "mass": { "chemical_mass": 22296.0, "monoisotopic_mass": 22296.0 }, "refseq": {}, "gene_names": [ { "name": "OSTF1", "type": "recommended", "evidence": [ { "id": "Q5ZJJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ] }, { "name": "RCJMB04_17j8", "type": "synonym", "evidence": [ { "id": "Q5ZJJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ] } ], "protein_names": [ { "name": "Osteoclast-stimulating factor 1", "type": "recommended", "evidence": [ { "id": "Q5ZJJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSTF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9", "locus": { "chromosome": "Z", "start_pos": 37491308, "end_pos": 37458525, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015493", "url": "https://www.ensembl.org/id/ENSGALG00010015493" } ] } } ], "crossref": [ { "id": "Q5ZJJ9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11772", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11772", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJJ9", "url": "https://www.orthodb.org/?gene=Q5ZJJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24155:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24155:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJJ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKPPPKPAKPGQVKVFRALYTFEPRTPDELYFEEGDIIYISDMSDTNWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNQVGVNGLDKAGNTALYWACHGGHKDIVDVLFTQANLELNQQNKLGDTALHAAAWKGYADIVEMLLAKGARTDLKNNEKKLALDMATNAACASLLKKKQTAGTARTFK", "length": 202, "header": "sp|Q5ZJJ9-1|OSTF1_CHICK Isoform 1 of Osteoclast-stimulating factor 1 OS=Gallus gallus OX=9031 GN=OSTF1 PE=2 SV=1 CANONICAL=Q5ZJJ9-1" }, "isoforms": [ { "isoform_ac": "Q5ZJJ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9/entry#Q5ZJJ9-1", "sequence": { "sequence": "MSKPPPKPAKPGQVKVFRALYTFEPRTPDELYFEEGDIIYISDMSDTNWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNQVGVNGLDKAGNTALYWACHGGHKDIVDVLFTQANLELNQQNKLGDTALHAAAWKGYADIVEMLLAKGARTDLKNNEKKLALDMATNAACASLLKKKQTAGTARTFK", "length": 202, "header": "sp|Q5ZJJ9-1|OSTF1_CHICK Isoform 1 of Osteoclast-stimulating factor 1 OS=Gallus gallus OX=9031 GN=OSTF1 PE=2 SV=1 CANONICAL=Q5ZJJ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJJ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 202, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJJ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJJ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ9" }, { "id": "PRU00192", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000255", "start_pos": 12, "end_pos": 71, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJK5-1", "uniprot_ac": "Q5ZJK5", "uniprot_id": "LCORL_CHICK", "mass": { "chemical_mass": 67186.0, "monoisotopic_mass": 67186.0 }, "refseq": { "ac": "NP_001026331", "name": "ligand-dependent nuclear receptor corepressor-like protein isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331" }, "gene_names": [ { "name": "LCORL", "type": "recommended", "evidence": [ { "id": "Q5ZJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5" } ] }, { "name": "LCORL", "type": "synonym", "evidence": [ { "id": "NP_001026331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331" } ] }, { "name": "RCJMB04_17h17", "type": "synonym", "evidence": [ { "id": "Q5ZJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5" } ] } ], "protein_names": [ { "name": "Ligand-dependent nuclear receptor corepressor-like protein", "type": "recommended", "evidence": [ { "id": "Q5ZJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5/entry#names_and_taxonomy" } ] }, { "name": "ligand-dependent nuclear receptor corepressor-like protein isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001026331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331" } ] }, { "name": "ligand-dependent nuclear receptor corepressor-like protein", "type": "synonym", "evidence": [ { "id": "NP_001026331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.5103.1, SRR13267659.89531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On or before Dec 21, 2020 this sequence version replaced XP_015141205.1, NP_001026331.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331" } ] }, { "annotation": "May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LCORL", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5", "locus": { "chromosome": "4", "start_pos": 75427097, "end_pos": 75407671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010958", "url": "https://www.ensembl.org/id/ENSGALG00010010958" } ] } } ], "crossref": [ { "id": "Q5ZJK5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014421", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014421", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422820", "url": "https://www.ncbi.nlm.nih.gov/gene/422820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422820", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLQYETH", "url": "https://omabrowser.org/oma/group/SLQYETH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJK5", "url": "https://www.orthodb.org/?gene=Q5ZJK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21545:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21545:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJK5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJK5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJK5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJK5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKGTDRMAAAAPAPPAAASQCRSPRCTAERRGVRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMDEKCSFCNLHKETVSDRASVIGSSQSTPTEELSSQGQSNTDKIECQAENYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSSKIQENRNGSSFEPSLICKSIQMNQTENSLQEEQDSPLDLTVNRTQEQNTQQGDGVLDLSTKKSARLEEPKYDPLCSENSVSGRLHRHREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPAPFKNKTRDFNDSYSFKDSKETCAVLQKVALWARAQAERTEKSKLSLLETSELKFPTASSYLHQLTLQRMVTQFKEKSENLQYETTNPTVQLKIPQLRISSVSKPQSDTAGLLDVMYHVSKTSSVLEGSALQKLKNILPKQNKIECSGPVTHSSVDSYFLHGDLSPLCLNAKNGTVDGTSENTEDSLDRKDNKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLFNMTDSGTGSCKTSSKPV", "length": 600, "header": "sp|Q5ZJK5-1|LCORL_CHICK Isoform 1 of Ligand-dependent nuclear receptor corepressor-like protein OS=Gallus gallus OX=9031 GN=LCORL PE=2 SV=2 CANONICAL=Q5ZJK5-1" }, "isoforms": [ { "isoform_ac": "Q5ZJK5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5/entry#Q5ZJK5-1", "sequence": { "sequence": "MEKGTDRMAAAAPAPPAAASQCRSPRCTAERRGVRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMDEKCSFCNLHKETVSDRASVIGSSQSTPTEELSSQGQSNTDKIECQAENYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSSKIQENRNGSSFEPSLICKSIQMNQTENSLQEEQDSPLDLTVNRTQEQNTQQGDGVLDLSTKKSARLEEPKYDPLCSENSVSGRLHRHREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPAPFKNKTRDFNDSYSFKDSKETCAVLQKVALWARAQAERTEKSKLSLLETSELKFPTASSYLHQLTLQRMVTQFKEKSENLQYETTNPTVQLKIPQLRISSVSKPQSDTAGLLDVMYHVSKTSSVLEGSALQKLKNILPKQNKIECSGPVTHSSVDSYFLHGDLSPLCLNAKNGTVDGTSENTEDSLDRKDNKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLFNMTDSGTGSCKTSSKPV", "length": 600, "header": "sp|Q5ZJK5-1|LCORL_CHICK Isoform 1 of Ligand-dependent nuclear receptor corepressor-like protein OS=Gallus gallus OX=9031 GN=LCORL PE=2 SV=2 CANONICAL=Q5ZJK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJK5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GLM1-1", "protein_name": "Ligand dependent nuclear receptor corepressor-like", "gene_name": "Lcorl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGNNYSVQITTFYCSSIIGHQDCEPEELTDWSMDEKCSFCNLQREAVSDCMPSLDSSQSTPTEELSSQGQSHTDKIECQAETYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSGKIQENRNGSIGASLVCKSIQMNQAENCLQDEQEGPLDLTVTRTHEQTAQQGDGVLDLSTKKTSIKSEESSMCAPPSESAVAGRLHRNREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPATFKNKTRDFNDSYSYKESKETCAVLQKVALWARAQTERTEKSKLNLLETSELKFPTASSYLHQLTLQKMVTQFKEKNESLQYETSNPTVQLKIPQLRVNSVSKSQPDGSGLLDVMYQVSKTSSVLEGSALQKLKNILPKQNKIECSGPVTHSSVDSYFLHGDLSPLCLNSKNGTVDGASENTEDGLDRKDSKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLYMTDSGTGSCRNSSKPV", "length": 550 }, "evidence": [ { "id": "Q5ZJK5", "url": "https://omabrowser.org/oma/group/Q5ZJK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U285-1", "protein_name": "Ligand-dependent nuclear receptor corepressor-like protein", "gene_name": "Lcorl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKGRERMAAAAAAAAAAAAAQCRSPRCAAERRGFRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMDEKCSFCNLQREAVSDCIPSLDSSQSTPTEELSSQGQSHTDKIECQAESYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSGKIQENRNGSIGASLVCKSIQMNQADNCLQDEQEGPLDLTVTRTQEQTAQQGDGVLDLSTKKTSIKSEESSISDPSSENAVAGRLHRNREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPASFKNKTRDFNDSYSYNESKETCAVLQKVALWARAQTERTEKSKLNLLETSEFKFPTASSYLHQLTLQKMVTQFKEKNESLQYETSNPPVQLKIPQLRVNSVSKSQADGSGLLDVMYQVSKTSSVLEGSALQKLKNILPKQNKLDCSGPVTHSSVDSYFLHGDLSPLCLNSKNGTVDGTSENTEDGLDRKDNKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLYMTDSGTGSCRNSSKPV", "length": 600 }, "evidence": [ { "id": "Q5ZJK5", "url": "https://omabrowser.org/oma/group/Q5ZJK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3X6-1", "protein_name": "Ligand-dependent nuclear receptor corepressor-like protein", "gene_name": "LCORL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKGRERMAAAAAAAAAAAAAAQCRSPRCAAERRGFRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMDEKCSFCNLQREAVSDCIPSLDSSQSTPTEELSSQGQSNTDKIECQAENYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSGKTQENRNGSIGPSIVCKSIQMNQAENSLQEEQEGPLDLTVNRMQEQNTQQGDGVLDLSTKKTSIKSEESSICDPSSENSVAGRLHRNREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPASFKNKTRDFHDSYSYKDSKETCAVLQKVALWARAQAERTEKSKLNLLETSEIKFPTASTYLHQLTLQKMVTQFKEKNESLQYETSNPTVQLKIPQLRVSSVSKSQPDGSGLLDVMYQVSKTSSVLEGSALQKLKNILPKQNKIECSGPVTHSSVDSYFLHGDLSPLCLNSKNGTVDGTSENTEDGLDRKDSKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLYNMTDSGTGSCKNSSKPV", "length": 602 }, "evidence": [ { "id": "Q5ZJK5", "url": "https://omabrowser.org/oma/group/Q5ZJK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": 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"MCGICCVVALSSQHTICDYFSKDLHCHLRRRGPDSSQQLIKTVSEPSYECFFSGHVLHLRGLMTPQPLEDVNNNIFFWNGEIFNGVHVGDSENDTEVMFRHLALCSSEADILSLFSSLRGPWSFIYYQASGHSLWFGRDYFGRRSLLWQLSNVSDGAFCLTSVSVNSESCNQCQEVPASGIFKMDLRDCATTKSLSLTLFPWKYKCTEKNEEEIFIDVLDQVSKDLPNHITVVMNESKLCLSAPVIPLNRTISEASVEHVSSDSSKTSSVVSLETLQGYLAVEHKRKVVHQFIDVLDEAVKRRVLLLRRGEDEGTGQVQGVSPRKAHVAVLFSGGVDSMVIAALADRHVPLEEPIDLLNVAFMTKEQTKRTGTTKNCIRQEMKLDLHRGEENHKDLDAKMGDDLSCFDVPDRITGRAGLKELEALNPSRTWNFVEINVTLKELKEMRRRFINHLIYPLDTVLDDSIGCAIWFASRGEGYINKQGEMKPYKSPAKVVLTGIGADEQLAGYSRHRICFRKCGPEGLNKELEMELGRISSRNLGRDDRIIGDHGKEARFPFIDEDVVSFLNSLPISEKADLTLPRGVGEKLILRLGAKELGLEAASILPKRAVQFGSRIAKLESNNEKAYHTCSRLKLF", "length": 636, "header": "sp|Q5ZJN0-1|ASND1_CHICK Isoform 1 of Asparagine synthetase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ASNSD1 PE=2 SV=1 CANONICAL=Q5ZJN0-1" }, "isoforms": [ { "isoform_ac": "Q5ZJN0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN0/entry#Q5ZJN0-1", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/Q5ZJN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 636, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJN0" } ], "lectin_list": [], "domain_list": [ { 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"https://www.uniprot.org/uniprotkb/Q5ZJN1/entry#names_and_taxonomy" } ] }, { "name": "RTF2", "type": "synonym", "evidence": [ { "id": "Q5ZJN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1/entry#names_and_taxonomy" } ] }, { "name": "Replication termination factor 2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZJN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Replication termination factor which is a component of the elongating replisome. Interacts with nascent DNA.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1#function" }, { "database": "UniProtKB", "id": "Q9BY42", "url": "https://www.uniprot.org/uniprotkb/Q9BY42#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTF2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1", "locus": {} } ], "crossref": [ { "id": "Q5ZJN1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16653", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16653", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12775:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12775:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJN1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCDGGTIPKRHELVKGPRKAVKVDKTAELVARWYYCTLSQEKLCRPIVACELGRLYNKDAVIEFLLDKSADKTPMEAASHIKSLKNVTELNLADNPAWSGDKESKKGDTYDDIQSARFICPVVGLEMNGRHRFCFLRNCGCVFSERALKEIKTEVCHKCGVPFQEEDVIILNGNKEDVEVLKKRMEDRRLKSKLEKKSKKCKSAESAAQQVTTEDSPGPSKVKNSKDCIASSSGEKRHIIFTKSSDDRSSSVPGKVNKASTATKRSIADTATRNLRHTNLFTTHSSAKRPKEECSNWVTHTAYCF", "length": 306, "header": "sp|Q5ZJN1-1|RTF2_CHICK Isoform 1 of Replication termination factor 2 OS=Gallus gallus OX=9031 GN=RTF2 PE=2 SV=1 CANONICAL=Q5ZJN1-1" }, "isoforms": [ { "isoform_ac": "Q5ZJN1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1/entry#Q5ZJN1-1", "sequence": { "sequence": "MGCDGGTIPKRHELVKGPRKAVKVDKTAELVARWYYCTLSQEKLCRPIVACELGRLYNKDAVIEFLLDKSADKTPMEAASHIKSLKNVTELNLADNPAWSGDKESKKGDTYDDIQSARFICPVVGLEMNGRHRFCFLRNCGCVFSERALKEIKTEVCHKCGVPFQEEDVIILNGNKEDVEVLKKRMEDRRLKSKLEKKSKKCKSAESAAQQVTTEDSPGPSKVKNSKDCIASSSGEKRHIIFTKSSDDRSSSVPGKVNKASTATKRSIADTATRNLRHTNLFTTHSSAKRPKEECSNWVTHTAYCF", "length": 306, "header": "sp|Q5ZJN1-1|RTF2_CHICK Isoform 1 of Replication termination factor 2 OS=Gallus gallus OX=9031 GN=RTF2 PE=2 SV=1 CANONICAL=Q5ZJN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJN1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJN1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJN1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJN1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"gene_names": [ { "name": "FNDC3A", "type": "recommended", "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ] }, { "name": "FNDC3A", "type": "synonym", "evidence": [ { "id": "NP_001012844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012844" } ] }, { "name": "FNDC3", "type": "synonym", "evidence": [ { "id": "NP_001012844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012844" }, { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ] }, { "name": "RCJMB04_16k12", "type": "synonym", "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ] } ], "protein_names": [ { "name": "Fibronectin type-III domain-containing protein 3a", "type": "recommended", "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5/entry#names_and_taxonomy" } ] }, { "name": "fibronectin type-III domain-containing protein 3a", "type": "synonym", "evidence": [ { "id": "NP_001012844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012844" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720389.1, SRR13267655.10331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000027.1. On Sep 23, 2021 this sequence version replaced NP_001012844.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012844" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FNDC3A", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5", "locus": { "chromosome": "1", "start_pos": 168992872, "end_pos": 168878579, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003986", "url": "https://www.ensembl.org/id/ENSGALG00010003986" } ] } } ], "crossref": [ { "id": "Q5ZJP5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418863", "url": "https://www.ncbi.nlm.nih.gov/gene/418863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418863", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJP5", "url": "https://www.orthodb.org/?gene=Q5ZJP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJP5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJP5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJP5", "url": 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"length": 1198, "header": "sp|Q5ZJP5-1|FND3A_CHICK Isoform 1 of Fibronectin type-III domain-containing protein 3a OS=Gallus gallus OX=9031 GN=FNDC3A PE=2 SV=2 CANONICAL=Q5ZJP5-1" }, "isoforms": [ { "isoform_ac": "Q5ZJP5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5/entry#Q5ZJP5-1", "sequence": { "sequence": "MAEHPPLLDTSSIISSEIPLLTSPIVSGDGAQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPTIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGGHAVIHRPPHPPLPGFLPLPAMIPPPPRHIYSPVTGAGDMATQYIPQYHTSQMYGDLDTLPAHGRANFRDERSSKTYERLQKKLKDRHGTQKDKLNSPPSSPQKCPSPTSEPNGLTKGQDTAGISTGSTKSKSVGKGKSNSQTDVEIEEKDEETKALEALLSNIAKPVVSDVQARTALLMWSPPSIDVGEDTDKTNIPGVYTYEVMISNTGKDGKYKTVYIGEENKVTVNDLRPATDYHAKVQVECNCVKGSPSEVESFTTMSCEPDAPNLPRITNRTKNSLTLQWKASCDNGSKIHSYLLEWDEGKGNGEFCQCYYGQQKQYRITKLSPAMGYTFRLAAKNDMGMSGFSEEVLYHTSGTAATTPASPLLINAGVTWLSLQWTKPSGTPSDEGISYILEMEDENSGYGFKPKYDGDDLTYTVKNLRRSTKYKFRVIAYNSEGKSSPSETVDYTTCPDKPGAPSKPSVKGKIHAQSFKIIWDPPKDNGGAAINTYVVEISEGSNGNKWDTIYSGAAREHLCDRLNPGCSYRLRVYCIGEGGQSMASDSLLVQTPAVVPGPCQPPRLQGRPRAREIQLRWGPPQVDGGSPITCYGLEMFQTETDEHREVYQGSDVECTVGSLLPGRMYNFRLRAANKAGFGPYSEKCEITTAPGPPDQCKPPQVTCRSAACAQVSWEVPVSNGADVTEYRLEWGGMEGCMQISYCGPGLNCEMKGLLPATIYYCRVQAVNVAGAGPFSEVVACMTPASVPAVVTCLRGLSEDEVESPHYYPSTCLALSWEKPCDHGSEITGYSIDFGDKQPITVGKVLSYFIDGLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPRLECVAYSSQTLKLKWGEGTAKALTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLSESTSYKFCIQACNEAGEGPLSQEYVFTTPKSVPAALKAPRIERINDHTCEITWEVLQPMKGDPVIYCLQVMVGKDSEFKQIYKGPDWSFRYTGLQLNCEYRFRACAIRQCQETSGHQDLIGPYSSPVLFISQRTEPPTSTNKDTVQTTRTQWSQSDQVCAAVILALFAIFSILIAVIIQYFVIK", "length": 1198, "header": "sp|Q5ZJP5-1|FND3A_CHICK Isoform 1 of Fibronectin type-III domain-containing protein 3a OS=Gallus gallus OX=9031 GN=FNDC3A PE=2 SV=2 CANONICAL=Q5ZJP5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 494, "start_aa": "Thr", "end_pos": 494, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr494", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418863", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP5", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1198, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJP5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", 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"" }, { "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 4", "eco_id": "ECO_0000255", "start_pos": 567, "end_pos": 661, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 5", "eco_id": "ECO_0000255", "start_pos": 665, "end_pos": 758, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZJP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP5" }, { "id": "PRU00316", "database": "PROSITE", 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJP7-1", "uniprot_ac": "Q5ZJP7", "uniprot_id": "KCTD7_CHICK", "mass": { "chemical_mass": 33228.0, "monoisotopic_mass": 33228.0 }, "refseq": { "ac": "NP_001034358", "name": "BTB/POZ domain-containing protein KCTD7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358" }, "gene_names": [ { "name": "KCTD7", "type": "recommended", "evidence": [ { "id": "Q5ZJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ] }, { "name": "KCTD7", "type": "synonym", "evidence": [ { "id": "NP_001034358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358" } ] }, { "name": "RCJMB04_16j10", "type": "synonym", "evidence": [ { "id": "Q5ZJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD7", "type": "recommended", "evidence": [ { "id": "Q5ZJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7/entry#names_and_taxonomy" } ] }, { "name": "BTB/POZ domain-containing protein KCTD7", "type": "synonym", "evidence": [ { "id": "NP_001034358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358" } ] }, { "name": "potassium channel tetramerisation domain containing 7", "type": "synonym", "evidence": [ { "id": "NP_001034358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720387.1, HAEK01028798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Jan 31, 2006 this sequence version replaced XP_415795.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001034358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358" } ] }, { "annotation": "May be involved in the control of excitability of cortical neurons.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7", "locus": { "chromosome": "19", "start_pos": 5516339, "end_pos": 5509570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029672", "url": "https://www.ensembl.org/id/ENSGALG00010029672" } ] } } ], "crossref": [ { "id": "Q5ZJP7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002618", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417547", "url": "https://www.ncbi.nlm.nih.gov/gene/417547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417547", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAAEQQC", "url": "https://omabrowser.org/oma/group/IAAEQQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJP7", "url": "https://www.orthodb.org/?gene=Q5ZJP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJP7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJP7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001034358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJP7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVVTGQSKGSGDPDEAMSSSDAEDDFQEPATPTATQAGQALPLLPQQFPEVVPLNVGGMHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGTYFGDILNFLRSGDLPPRERVRPVYKEAQYYSIGPLLDHLEDVQPLKGEKVRQAFLGLMPYYKDHLERIIEIAKLRAVQRKARFAKLKVCVFKEEMPITPYECPHFNSLRFERSESEAKLFEHHCEVDVSFGPWEAVADVYDLLHCIVTDLSDRGITVDHQCIGVCDKHLINHYYCKRPIYEFKITWW", "length": 289, "header": "sp|Q5ZJP7-1|KCTD7_CHICK Isoform 1 of BTB/POZ domain-containing protein KCTD7 OS=Gallus gallus OX=9031 GN=KCTD7 PE=2 SV=1 CANONICAL=Q5ZJP7-1" }, "isoforms": [ { "isoform_ac": "Q5ZJP7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7/entry#Q5ZJP7-1", "sequence": { "sequence": "MVVVTGQSKGSGDPDEAMSSSDAEDDFQEPATPTATQAGQALPLLPQQFPEVVPLNVGGMHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGTYFGDILNFLRSGDLPPRERVRPVYKEAQYYSIGPLLDHLEDVQPLKGEKVRQAFLGLMPYYKDHLERIIEIAKLRAVQRKARFAKLKVCVFKEEMPITPYECPHFNSLRFERSESEAKLFEHHCEVDVSFGPWEAVADVYDLLHCIVTDLSDRGITVDHQCIGVCDKHLINHYYCKRPIYEFKITWW", "length": 289, "header": "sp|Q5ZJP7-1|KCTD7_CHICK Isoform 1 of BTB/POZ domain-containing protein KCTD7 OS=Gallus gallus OX=9031 GN=KCTD7 PE=2 SV=1 CANONICAL=Q5ZJP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417547", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P3Y5-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "KCTD7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVVVTGQSKGSGDPDEAMSSSDAEDDFQEPATPTATQAGQALPLLPQQFPEVVPLNVGGMHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGTYFGDILNFLRSGDLPPRERVRPVYKEAQYYSIGPLLDHLEDVQPLKGEKVRQAFLGLMPYYKDHLERIIEIAKLRAVQRKARFAKLKVCVFKEEMPITPYECPHFNSLRFERSESEAKLFEHHCEVDVSFGPWEAVADVYDLLHCIVTDLSDRGITVDHQCIGVCDKHLINHYYCKRPIYEFKITW", "length": 288 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A5G2QV46-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "KCTD7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVVVTGREPDNRRPDGAMSSSDAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGAYFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLINHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFB4-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "KCTD7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVVVTGREPDSRRPDGAMSSSDAEDDFLEPATPTATQAGHSLPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDAEGRYFIDRDGAHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLINHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B1WC97-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "Kctd7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVVNGREPDSRHSDGAMSSSEAEDDFLEPATPTATQAGHGLPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPREHVRAVHKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IKG2-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "Kctd7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVVVTGREPDSRHWDGAMSSSEAEDDFLEPATPTATQAGHGLPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPREHVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLSSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VFV7-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "kctd7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVVFSAASDSEKPGDAMSGADKGEEEYRKPAIPVANLNLAKSLRTLDAPEEFPEVIPLNVGGTYFTTRLSTLRRYEDTMLAAMFSGRHHIPRDAEGRYFIDRDGTYFGDILNFLREGELPQRDRVRAVHREAQYYAIGPLLENLEDTQPLTGEKVRQAFLDLLPYYKENLERIVEIAKLRAMQRKARFAKLKICVYKEEMPITPYERPLFNSLRFERSESEAKLFEHHCEVDVSFGPWEAVADVYDLLHCIVSDLAERGISADQQCIGVCDKHLINHYYCKRPIYEFKITWW", "length": 292 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BJK1-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "Kctd7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVVTGREPDSRHSDGAMSSSEAEDDFLEPATPTATQAGHGLPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPREHVRAVHKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MP8-1", "protein_name": "BTB/POZ domain-containing protein KCTD7", "gene_name": "KCTD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVVTGREPDSRRQDGAMSSSDAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW", "length": 289 }, "evidence": [ { "id": "Q5ZJP7", "url": "https://omabrowser.org/oma/group/Q5ZJP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "pmid": "" }, { "name": "membrane hyperpolarization", "id": "GO:0060081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060081", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJP7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJP9-1", "uniprot_ac": "Q5ZJP9", "uniprot_id": "CCNL1_CHICK", "mass": { "chemical_mass": 59830.0, "monoisotopic_mass": 59830.0 }, "refseq": {}, "gene_names": [ { "name": "CCNL1", "type": "recommended", "evidence": [ { "id": "Q5ZJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ] }, { "name": "RCJMB04_16i10", "type": "synonym", "evidence": [ { "id": "Q5ZJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ] } ], "protein_names": [ { "name": "Cyclin-L1", "type": "recommended", "evidence": [ { "id": "Q5ZJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulatory component of the cyclin-L-CDK11 complex that regulates transcription and pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9#function" }, { "database": "UniProtKB", "id": "Q9UK58", "url": "https://www.uniprot.org/uniprotkb/Q9UK58#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNL1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9", "locus": { "chromosome": "9", "start_pos": 22492126, "end_pos": 22479774, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001495", "url": "https://www.ensembl.org/id/ENSGALG00010001495" } ] } } ], "crossref": [ { "id": "Q5ZJP9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395124", "url": "https://www.ncbi.nlm.nih.gov/gene/395124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJP9", "url": "https://www.orthodb.org/?gene=Q5ZJP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJP9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJP9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJP9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGSGSAAAVAAVAGGGPAGPHAAGVTAGAVTTGSGAPVPGPGAVLIGDRLYSGVLITLENCLLPEHTLRFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLILDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNTSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSGSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 534, "header": "sp|Q5ZJP9-1|CCNL1_CHICK Isoform 1 of Cyclin-L1 OS=Gallus gallus OX=9031 GN=CCNL1 PE=2 SV=1 CANONICAL=Q5ZJP9-1" }, "isoforms": [ { "isoform_ac": "Q5ZJP9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9/entry#Q5ZJP9-1", "sequence": { "sequence": "MAAGSGSAAAVAAVAGGGPAGPHAAGVTAGAVTTGSGAPVPGPGAVLIGDRLYSGVLITLENCLLPEHTLRFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLILDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNTSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSGSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 534, "header": "sp|Q5ZJP9-1|CCNL1_CHICK Isoform 1 of Cyclin-L1 OS=Gallus gallus OX=9031 GN=CCNL1 PE=2 SV=1 CANONICAL=Q5ZJP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:395124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395124", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJP9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 534, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJP9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 12366.0, "monoisotopic_mass": 12366.0 }, "refseq": { "ac": "NP_001007938", "name": "protein lin-52 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938" }, "gene_names": [ { "name": "LIN52", "type": "recommended", "evidence": [ { "id": "Q5ZJQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ] }, { "name": "LIN52", "type": "synonym", "evidence": [ { "id": "NP_001007938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938" } ] }, { "name": "RCJMB04_16g11", "type": "synonym", "evidence": [ { "id": "Q5ZJQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ] } ], "protein_names": [ { "name": "Protein lin-52 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZJQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3/entry#names_and_taxonomy" } ] }, { "name": "lin-52 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938" } ] }, { "name": "protein lin-52 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720381.1, HAEK01097042.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Dec 15, 2004 this sequence version replaced XP_421261.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJQ3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LIN52", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3", "locus": { "chromosome": "5", "start_pos": 37295205, "end_pos": 37252745, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006619", "url": "https://www.ensembl.org/id/ENSGALG00010006619" } ] } } ], "crossref": [ { "id": "Q5ZJQ3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000020419", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000020419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423346", "url": "https://www.ncbi.nlm.nih.gov/gene/423346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "4YOS", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=4YOS&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR018737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423346", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVQNTAY", "url": "https://omabrowser.org/oma/group/NVQNTAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJQ3", "url": "https://www.orthodb.org/?gene=Q5ZJQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31489:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31489:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00004yos", "url": "https://www.rcsb.org/structure/pdb_00004yos", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4YOS", "url": "https://www.rcsb.org/structure/4YOS", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF10044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJQ3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJQ3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJQ3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGDGADLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAELENDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 112, "header": "sp|Q5ZJQ3-1|LIN52_CHICK Isoform 1 of Protein lin-52 homolog OS=Gallus gallus OX=9031 GN=LIN52 PE=1 SV=1 CANONICAL=Q5ZJQ3-1" }, "isoforms": [ { "isoform_ac": "Q5ZJQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3/entry#Q5ZJQ3-1", "sequence": { "sequence": "MAAPGDGADLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAELENDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 112, "header": "sp|Q5ZJQ3-1|LIN52_CHICK Isoform 1 of Protein lin-52 homolog OS=Gallus gallus OX=9031 GN=LIN52 PE=1 SV=1 CANONICAL=Q5ZJQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJQ3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423346", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G1X6-1", "protein_name": "Protein lin-52 homolog", "gene_name": "Lin52", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGWKMASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDECLQLLGRDFSRESDFSKETDQPKDSSD", "length": 125 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LQU8-1", "protein_name": "Protein lin-52 homolog", "gene_name": "Lin52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGWKMASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPTWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 116 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AUQ6-1", "protein_name": "Protein lin-52 homolog", "gene_name": "lin52", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASPNGGEDFESSLISLENLDRASPDLWPEQLPGVSEFAASFKNPITNSPPKWMAELESEDIEMLKELGSLTTANLMEKVKGLQNLAYQLGLEESREMTRGKFLNILERPKK", "length": 112 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S3H0-1", "protein_name": "Protein lin-52 homolog", "gene_name": "LIN52", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGWKMASPTDGADLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 116 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q52LA3-1", "protein_name": "Protein lin-52 homolog", "gene_name": "LIN52", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 112 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CD94-1", "protein_name": "Protein lin-52 homolog", "gene_name": "Lin52", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK", "length": 112 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W482-1", "protein_name": "Lin-52, isoform A", "gene_name": "lin-52", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNAETTTDLLSTETILKAADEEVEKASASSSSTLLAEKDVPEVKERPITPEDELISMETLRPSPVQWPERFPGMDEFLSMSDTPMYTRSTNYTSNLTDDDMVKINELAQLPPEDLIDKIKSMHDEIYQLGLREAMEMTRGKLLGIFDRDRAPKRQP", "length": 157 }, "evidence": [ { "id": "Q5ZJQ3", "url": "https://omabrowser.org/oma/group/Q5ZJQ3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "DRM complex", "id": "GO:0070176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070176", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJQ3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJQ3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJQ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 112, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJQ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJQ3" }, { "pdb_id": "4yos", "pdb_chain": "e", "start_pos": 11, "end_pos": 30, "overlap": "1.0", "method": "X-Ray_Crystallography", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/4yos.pdb", "url_external": "https://www.rcsb.org/structure/4yos" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJR3-1", "uniprot_ac": "Q5ZJR3", "uniprot_id": "OSTC_CHICK", "mass": { "chemical_mass": 16743.0, "monoisotopic_mass": 16743.0 }, "refseq": { "ac": "NP_001006442", "name": "oligosaccharyltransferase complex subunit OSTC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" }, "gene_names": [ { "name": "OSTC", "type": "recommended", "evidence": [ { "id": "Q5ZJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ] }, { "name": "DC2", "type": "synonym", "evidence": [ { "id": "NP_001006442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" } ] }, { "name": "OSTC", "type": "synonym", "evidence": [ { "id": "NP_001006442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" } ] }, { "name": "RCJMB04_16e19", "type": "synonym", "evidence": [ { "id": "Q5ZJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ] } ], "protein_names": [ { "name": "Oligosaccharyltransferase complex subunit OSTC", "type": "recommended", "evidence": [ { "id": "Q5ZJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3/entry#names_and_taxonomy" } ] }, { "name": "oligosaccharyltransferase complex subunit (non-catalytic)", "type": "synonym", "evidence": [ { "id": "NP_001006442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" } ] }, { "name": "oligosaccharyltransferase complex subunit OSTC", "type": "synonym", "evidence": [ { "id": "NP_001006442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720371.1, HAEL01011555.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Jan 13, 2005 this sequence version replaced XP_420488.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006442", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442" } ] }, { "annotation": "Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3#function" }, { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSTC", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3", "locus": {} } ], "crossref": [ { "id": "Q5ZJR3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010526", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010526", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422525", "url": "https://www.ncbi.nlm.nih.gov/gene/422525", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422525", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422525", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWIFMRM", "url": "https://omabrowser.org/oma/group/CWIFMRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJR3", "url": "https://www.orthodb.org/?gene=Q5ZJR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13160:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13160:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJR3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJR3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006442", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006442", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJR3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLFRLPFAVLECPNIKLKRPGWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVSVLLSFFMARVFMRMKLPGYLMG", "length": 149, "header": "sp|Q5ZJR3-1|OSTC_CHICK Isoform 1 of Oligosaccharyltransferase complex subunit OSTC OS=Gallus gallus OX=9031 GN=OSTC PE=2 SV=1 CANONICAL=Q5ZJR3-1" }, "isoforms": [ { "isoform_ac": "Q5ZJR3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3/entry#Q5ZJR3-1", "sequence": { "sequence": "METLFRLPFAVLECPNIKLKRPGWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVSVLLSFFMARVFMRMKLPGYLMG", "length": 149, "header": "sp|Q5ZJR3-1|OSTC_CHICK Isoform 1 of Oligosaccharyltransferase complex subunit OSTC OS=Gallus gallus OX=9031 GN=OSTC PE=2 SV=1 CANONICAL=Q5ZJR3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422525", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422525", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UWE1-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "OSTC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LXK8-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0K025-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "Ostc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KID7-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSVTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q78XF5-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "Ostc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SZQ8-1", "protein_name": "Oligosaccharyltransferase complex/magnesium transporter family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPRSDSQTLATGSDENESSIDPIFHILRIIPFSFLRPPRLRLKLPSFTLPSPMTVFSLILLTYFLVVSGFVYDVIVEPPGIGSTQDPITGSVRPVVFMSGRVNGQYIIEGLSSGFMFVLGGIGIIMLDLALDKNRAKSVKASYATAGVSSIVIAYVMSMLFIRIKIPGYLR", "length": 172 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VQP9-1", "protein_name": "Oligosaccharyltransferase complex subunit C", "gene_name": "Ostc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIETLYNLPFHILVPPNIKVRRFSIPMPSPMAVFSVILFSYFLVTGGIIYDVIVEPPSLGATVDEHGHSRPVAFMPYRVNGQYIMEGLASSFLFTVGGLGFIIMDQTHTPGKTNLNRLLLTAMGFIFILVSFFTTWLFMRMKLPSYLQP", "length": 149 }, "evidence": [ { "id": "Q5ZJR3", "url": "https://omabrowser.org/oma/group/Q5ZJR3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJR3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJR3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJU2-1", "uniprot_ac": "Q5ZJU2", "uniprot_id": "KLH15_CHICK", "mass": { "chemical_mass": 56659.0, "monoisotopic_mass": 56659.0 }, "refseq": { "ac": "NP_001025973", "name": "kelch-like protein 15 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" }, "gene_names": [ { "name": "KLHL15", "type": "recommended", "evidence": [ { "id": "Q5ZJU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ] }, { "name": "KLHL15", "type": "synonym", "evidence": [ { "id": "NP_001025973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" } ] }, { "name": "RCJMB04_15l4", "type": "synonym", "evidence": [ { "id": "Q5ZJU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ] } ], "protein_names": [ { "name": "Kelch-like protein 15", "type": "recommended", "evidence": [ { "id": "Q5ZJU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2/entry#names_and_taxonomy" } ] }, { "name": "kelch like family member 15", "type": "synonym", "evidence": [ { "id": "NP_001025973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" } ] }, { "name": "kelch-like 15", "type": "synonym", "evidence": [ { "id": "NP_001025973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" } ] }, { "name": "kelch-like protein 15 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001025973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720342.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ738287.1, AJ720342.1, HAEK01005891.1 and JAENSK010000021.1. On Nov 24, 2021 this sequence version replaced NP_001025973.1. Transcript Variant: This variant (2) uses an alternate splice pattern in 5' UTR and the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001025973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973" } ] }, { "annotation": "Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2#function" }, { "database": "UniProtKB", "id": "Q96M94", "url": "https://www.uniprot.org/uniprotkb/Q96M94#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL15", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2", "locus": { "chromosome": "1", "start_pos": 118371030, "end_pos": 118347857, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003101", "url": "https://www.ensembl.org/id/ENSGALG00010003101" } ] } } ], "crossref": [ { "id": "Q5ZJU2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18454", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18454", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418598", "url": "https://www.ncbi.nlm.nih.gov/gene/418598", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418598", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418598", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJU2", "url": "https://www.orthodb.org/?gene=Q5ZJU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJU2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJU2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJU2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGDVEGFSSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFSVNIEGVREKLDSFLLENFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQAWLRHDRRRWRHTDTIIQNIRFCLMTPSSVFEKVKTSEFYRYSRQLRHEVDQAMNYFHSVHQQPLMEMKSNKIRSAKPQTAVFRGMIGHSMVNSKILLLHKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNTWLRMADMSVPRSEFAVGVIGRYVYAVAGRTRDETFYSTERYDITEDKWEFVDPYPVNKYGHEGTVLGNKLYITGGITSSSTSKQVCVFDPSKEGTVEQRTRRTQVATNCWENKCKMNYARCFHKMISYNA", "length": 488, "header": "sp|Q5ZJU2-1|KLH15_CHICK Isoform 1 of Kelch-like protein 15 OS=Gallus gallus OX=9031 GN=KLHL15 PE=2 SV=1 CANONICAL=Q5ZJU2-1" }, "isoforms": [ { "isoform_ac": "Q5ZJU2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2/entry#Q5ZJU2-1", "sequence": { "sequence": "MAGDVEGFSSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFSVNIEGVREKLDSFLLENFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQAWLRHDRRRWRHTDTIIQNIRFCLMTPSSVFEKVKTSEFYRYSRQLRHEVDQAMNYFHSVHQQPLMEMKSNKIRSAKPQTAVFRGMIGHSMVNSKILLLHKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNTWLRMADMSVPRSEFAVGVIGRYVYAVAGRTRDETFYSTERYDITEDKWEFVDPYPVNKYGHEGTVLGNKLYITGGITSSSTSKQVCVFDPSKEGTVEQRTRRTQVATNCWENKCKMNYARCFHKMISYNA", "length": 488, "header": "sp|Q5ZJU2-1|KLH15_CHICK Isoform 1 of Kelch-like protein 15 OS=Gallus gallus OX=9031 GN=KLHL15 PE=2 SV=1 CANONICAL=Q5ZJU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418598", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418598", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" }, { "name": "nuclear protein quality control by the ubiquitin-proteasome system", "id": "GO:0071630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071630", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJU2", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJU2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 488, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJU2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJU2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZJU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJU2" }, { "id": "PRU00037", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000255", "start_pos": 31, "end_pos": 98, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJV4-1", "uniprot_ac": "Q5ZJV4", "uniprot_id": "MCMBP_CHICK", "mass": { "chemical_mass": 71924.0, "monoisotopic_mass": 71924.0 }, "refseq": { "ac": "NP_001012930", "name": "mini-chromosome maintenance complex-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" }, "gene_names": [ { "name": "MCMBP", "type": "recommended", "evidence": [ { "id": "Q5ZJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ] }, { "name": "C10orf119", "type": "synonym", "evidence": [ { "id": "NP_001012930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" } ] }, { "name": "MCM-BP", "type": "synonym", "evidence": [ { "id": "NP_001012930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" } ] }, { "name": "MCMBP", "type": "synonym", "evidence": [ { "id": "NP_001012930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" } ] }, { "name": "RCJMB04_15g11", "type": "synonym", "evidence": [ { "id": "Q5ZJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ] } ], "protein_names": [ { "name": "Mini-chromosome maintenance complex-binding protein", "type": "recommended", "evidence": [ { "id": "Q5ZJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4/entry#names_and_taxonomy" } ] }, { "name": "MCM-BP", "type": "synonym", "evidence": [ { "id": "Q5ZJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4/entry#names_and_taxonomy" } ] }, { "name": "MCM-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001012930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" }, { "id": "Q5ZJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4/entry#names_and_taxonomy" } ] }, { "name": "mini-chromosome maintenance complex-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001012930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720330.1, BX950283.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720330.1. On Mar 14, 2005 this sequence version replaced XP_421793.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930" } ] }, { "annotation": "Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCMBP", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4", "locus": { "chromosome": "6", "start_pos": 31137411, "end_pos": 31154638, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002387", "url": "https://www.ensembl.org/id/ENSGALG00010002387" } ] } } ], "crossref": [ { "id": "Q5ZJV4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423933", "url": "https://www.ncbi.nlm.nih.gov/gene/423933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423933", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJV4", "url": "https://www.orthodb.org/?gene=Q5ZJV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13489:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13489:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJV4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJV4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012930", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJV4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCVADWLNNPFSIVQGIFAQNTPNSDWEKKVTDYFKEKLKENNATNWVPSLNDVPVHYLKPNSLVKFRCMVQDMFDPEFYMGVYETVDPNTNARVLHFGKYRDVAECGPQQEIDMNSSQTVTLERQTFYCVPVPGESAWVKEYLFSLQARVSPSTSYTPSRHKRSYEEDEDMEQHPSKQKEQHMGSGGDSHGCGEPKRLETEASAGHHLISPNCSPPLDLNFPLPGEKGPACLVKVYESWDTFKVNDVLEVYGILSVDPVLSIVNSEERDSSMLDPMECMDTAEEQRVHSPPSSLVPRIHVILAHKLQHLNPLLPACLNEEESKTFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYARRDVLPLGKFTVNLSGCPRNSIFTEHIYRIIQQLVPASYRLQMTIENMNHSRFIPRKDYTANRLVSGILQLASNTSLVIDETQLEQGQLDTKGVHNVKALGNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPSDCQVQLQPQIIPPNMEEYMNSLLTAVLPSVLNKFRIYLSLLRLLDYSISDEVTKAVEEDFVEMRKNDPESITADDLHRTLLVARFLSLSAGQTTLSRERWLRAKQLEALRKARLQQQKCVNGNEL", "length": 633, "header": "sp|Q5ZJV4-1|MCMBP_CHICK Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Gallus gallus OX=9031 GN=MCMBP PE=2 SV=2 CANONICAL=Q5ZJV4-1" }, "isoforms": [ { "isoform_ac": "Q5ZJV4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4/entry#Q5ZJV4-1", "sequence": { "sequence": "MPCVADWLNNPFSIVQGIFAQNTPNSDWEKKVTDYFKEKLKENNATNWVPSLNDVPVHYLKPNSLVKFRCMVQDMFDPEFYMGVYETVDPNTNARVLHFGKYRDVAECGPQQEIDMNSSQTVTLERQTFYCVPVPGESAWVKEYLFSLQARVSPSTSYTPSRHKRSYEEDEDMEQHPSKQKEQHMGSGGDSHGCGEPKRLETEASAGHHLISPNCSPPLDLNFPLPGEKGPACLVKVYESWDTFKVNDVLEVYGILSVDPVLSIVNSEERDSSMLDPMECMDTAEEQRVHSPPSSLVPRIHVILAHKLQHLNPLLPACLNEEESKTFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYARRDVLPLGKFTVNLSGCPRNSIFTEHIYRIIQQLVPASYRLQMTIENMNHSRFIPRKDYTANRLVSGILQLASNTSLVIDETQLEQGQLDTKGVHNVKALGNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPSDCQVQLQPQIIPPNMEEYMNSLLTAVLPSVLNKFRIYLSLLRLLDYSISDEVTKAVEEDFVEMRKNDPESITADDLHRTLLVARFLSLSAGQTTLSRERWLRAKQLEALRKARLQQQKCVNGNEL", "length": 633, "header": "sp|Q5ZJV4-1|MCMBP_CHICK Isoform 1 of Mini-chromosome maintenance complex-binding protein OS=Gallus gallus OX=9031 GN=MCMBP PE=2 SV=2 CANONICAL=Q5ZJV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423933", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "pmid": "" }, { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJV4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 633, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJV4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJV4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJV6-1", "uniprot_ac": "Q5ZJV6", "uniprot_id": "RCAN3_CHICK", "mass": { "chemical_mass": 28301.0, "monoisotopic_mass": 28301.0 }, "refseq": { "ac": "NP_001026078", "name": "calcipressin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078" }, "gene_names": [ { "name": "RCAN3", "type": "recommended", "evidence": [ { "id": "Q5ZJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ] }, { "name": "RCAN3", "type": "synonym", "evidence": [ { "id": "NP_001026078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078" } ] }, { "name": "RCJMB04_15g5", "type": "synonym", "evidence": [ { "id": "Q5ZJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ] } ], "protein_names": [ { "name": "Calcipressin-3", "type": "recommended", "evidence": [ { "id": "Q5ZJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6/entry#names_and_taxonomy" } ] }, { "name": "Regulator of calcineurin 3", "type": "synonym", "evidence": [ { "id": "Q5ZJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6/entry#names_and_taxonomy" } ] }, { "name": "calcipressin-3", "type": "synonym", "evidence": [ { "id": "NP_001026078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078" } ] }, { "name": "regulator of calcineurin 3", "type": "synonym", "evidence": [ { "id": "NP_001026078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720328.1, SRR13267654.245931.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000339.1. On Aug 8, 2005 this sequence version replaced XP_417844.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078" } ] }, { "annotation": "Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RCAN3", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6", "locus": { "chromosome": "23", "start_pos": 6143548, "end_pos": 6136272, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015923", "url": "https://www.ensembl.org/id/ENSGALG00010015923" } ] } } ], "crossref": [ { "id": "Q5ZJV6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004282", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004282", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12710", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12710", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419698", "url": "https://www.ncbi.nlm.nih.gov/gene/419698", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419698", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419698", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMHRERF", "url": "https://omabrowser.org/oma/group/DMHRERF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJV6", "url": "https://www.orthodb.org/?gene=Q5ZJV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10300:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10300:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJV6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJV6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJV6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRDTMKSWSDSQSDLYSSDQEEEEQMIFGENEDDFEEMMDLSDLPTSLFACSVHEAVFEVQEEKERFEALFTVYDNQVTFQLFKSFRRVRINFSNPEAAARARIELHETDFSGKKLKLYFAQVQVSSEVGDKSYLLPPQPVKQFLISPPASPPVGWKQSEDATPLINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEEIKNPKQKIMQTRRPEPPATILNESKAFDCTLEVGGTIHC", "length": 249, "header": "sp|Q5ZJV6-1|RCAN3_CHICK Isoform 1 of Calcipressin-3 OS=Gallus gallus OX=9031 GN=RCAN3 PE=2 SV=2 CANONICAL=Q5ZJV6-1" }, "isoforms": [ { "isoform_ac": "Q5ZJV6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6/entry#Q5ZJV6-1", "sequence": { "sequence": "MLRDTMKSWSDSQSDLYSSDQEEEEQMIFGENEDDFEEMMDLSDLPTSLFACSVHEAVFEVQEEKERFEALFTVYDNQVTFQLFKSFRRVRINFSNPEAAARARIELHETDFSGKKLKLYFAQVQVSSEVGDKSYLLPPQPVKQFLISPPASPPVGWKQSEDATPLINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEEIKNPKQKIMQTRRPEPPATILNESKAFDCTLEVGGTIHC", "length": 249, "header": "sp|Q5ZJV6-1|RCAN3_CHICK Isoform 1 of Calcipressin-3 OS=Gallus gallus OX=9031 GN=RCAN3 PE=2 SV=2 CANONICAL=Q5ZJV6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419698", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419698", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IB17-1", "protein_name": "Calcipressin-3", "gene_name": "Rcan3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRDTMKSWNDSQSDLCSSDQEEEEEMVFGENEDELEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTLYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHESDFHGQKLKLYFAQVQVSGEARDKSYLLPPQPTKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEDTKNPKQKITQTRRPEAPTAALSEQLDCAL", "length": 239 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1VR01-1", "protein_name": "RCAN family member 3", "gene_name": "RCAN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGRHLRTLKTEKTCFEGTVLRDTMKSWSDSQSDLCSSDQEEEDMIFGENEEDLEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGKKLKLYFAQVQVSSETRDRSYLLPPQPVKQFLISPPASPPVGWKQGEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETRTPKQKITQTRRPEPPPAALSEPRAFDCAL", "length": 259 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7ENE7-1", "protein_name": "RCAN family member 3", "gene_name": "Rcan3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRARRTRPFGAPPTTRRLPPTQLSAPPSCLCAGAAHPLGARNPGRARGARVRERARRRRPHSAPGHRPCSRLRWPLGPASRAWWLPAVKVCPPLAVLVSPPGPLPWSAQDAGIVALLCFPGFWKLVVRLLLKHRAFNSCFQAAGFQLPCEISSSPLALSGQRPRTLPTEKMLRDSLKSWNDSQSDLCSSDQEEEEEMVFGENEDDLEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTLYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHESEFHGRKLKLYFAQVQVSGEARDKSYLLPPQPTKQFLISPPASPPVGWKQSEDATPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEDTKNPKQKITQTRRPEAPTAALSERLDCAL", "length": 409 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIA1-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRDTMNSWNDSQSDLCSTDHEEEEEMVFGENEDDLEEMMDLSDLPTSLFACRVHEAVFEVPEQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGRKLKLYFAQVQMSGETRDKSYLQPPQPAKQFLISPPASPPVGWKQGGDATPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETKNPKQKITQTRRPEPPTAALSEPRAFDCAL", "length": 241 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JKK0-1", "protein_name": "Calcipressin-3", "gene_name": "Rcan3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRDSLKSWNDSQSDLCSSDQEEEEEMVFGENEDGLEEMMDLSDLPTSLFACSVHEAVFEVQEQKERFEALFTLYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHESEFHGRKLKLYFAQVQVSGEARDKSYLLPPQPTKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEDTKNPKQKITQTRRPEAPTAALSERLDCAL", "length": 239 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRDTMKSWNDSQSDLCSTDQEEEEEMIFGENEDDLDEMMDLSDLPTSLFACSVHEAVFEAREQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGQKLKLYFAQVQMSGEVRDKSYLLPPQPVKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETKNPKQKIAQTRRPDPPTAALNEPQTFDCAL", "length": 241 }, "evidence": [ { "id": "Q5ZJV6", "url": "https://omabrowser.org/oma/group/Q5ZJV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "pmid": "" }, { "name": "calcium-dependent protein serine/threonine phosphatase regulator activity", "id": "GO:0008597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008597", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV6", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJV6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 249, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJV6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJV6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 193 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZJV7-1", "uniprot_ac": "Q5ZJV7", "uniprot_id": "SHCAF_CHICK", "mass": { "chemical_mass": 24968.0, "monoisotopic_mass": 24968.0 }, "refseq": { "ac": "NP_001025937", "name": "SIN3-HDAC complex-associated factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" }, "gene_names": [ { "name": "SINHCAF", "type": "recommended", "evidence": [ { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7" } ] }, { "name": "FAM60A", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" }, { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7" } ] }, { "name": "RCJMB04_15g2", "type": "synonym", "evidence": [ { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7" } ] }, { "name": "SINHCAF", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] } ], "protein_names": [ { "name": "SIN3-HDAC complex-associated factor", "type": "recommended", "evidence": [ { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM60A", "type": "synonym", "evidence": [ { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7/entry#names_and_taxonomy" } ] }, { "name": "SIN3-HDAC complex associated factor", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] }, { "name": "SIN3-HDAC complex-associated factor", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] }, { "name": "Tera protein homolog", "type": "synonym", "evidence": [ { "id": "Q5ZJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7/entry#names_and_taxonomy" } ] }, { "name": "protein FAM60A", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] }, { "name": "tera protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001025937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720327.1, SRR13267655.203729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001025937.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ] }, { "annotation": "FAM60A promotes osteosarcoma development and progression.", "evidence": [ { "database": "RefSeq", "id": "NP_001025937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" }, { "database": "PubMed", "id": "37439040", "url": "https://glygen.org/publication/PubMed/37439040" } ] }, { "annotation": "Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells and is essential to maintain the complex on chromatin.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7#function" }, { "database": "UniProtKB", "id": "Q9NP50", "url": "https://www.uniprot.org/uniprotkb/Q9NP50#function" }, { "database": "UniProtKB", "id": "Q8C8M1", "url": "https://www.uniprot.org/uniprotkb/Q8C8M1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SINHCAF", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7", "locus": {} } ], "crossref": [ { "id": "Q5ZJV7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "418140", "url": "https://www.ncbi.nlm.nih.gov/gene/418140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418140", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZJV7", "url": "https://www.orthodb.org/?gene=Q5ZJV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13422:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13422:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJV7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZJV7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZJV7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZJV7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGFRKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 222, "header": "sp|Q5ZJV7-1|SHCAF_CHICK Isoform 1 of SIN3-HDAC complex-associated factor OS=Gallus gallus OX=9031 GN=SINHCAF PE=2 SV=1 CANONICAL=Q5ZJV7-1" }, "isoforms": [ { "isoform_ac": "Q5ZJV7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7/entry#Q5ZJV7-1", "sequence": { "sequence": "MFGFRKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 222, "header": "sp|Q5ZJV7-1|SHCAF_CHICK Isoform 1 of SIN3-HDAC complex-associated factor OS=Gallus gallus OX=9031 GN=SINHCAF PE=2 SV=1 CANONICAL=Q5ZJV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJV7", "url": "https://www.uniprot.org/uniprotkb/Q5ZJV7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "FAM60A promotes osteosarcoma development and progression.", "journal": "Cancer medicine", "date": "2023-08", "authors": "Sun Yu, Man Yu-Nan, Cheng Jin-Hui, Li Jing-Tang, Liu Ya-Yun", "evidence": [ { "database": "RefSeq", "id": "NP_001025937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025937" } ], "reference": [ { "type": "PubMed", "id": "37439040", "url": "https://glygen.org/publication/PubMed/37439040" } ] } ], "pathway": [ { "id": "gga:418140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418140", "resource": "KEGG Pathway" } ], 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"glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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The reference sequence was derived from AJ720310.1, AJ399148.1 and BU144792.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001292022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292022" } ] }, { "annotation": "RNA-binding protein that specifically bind the 3'-UTR of some transcripts, leading to maintain their stability. Also acts as a mRNA splicing factor. May play a role in myogenic differentiation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZJX4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJX4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZJX4", "url": "https://www.uniprot.org/uniprotkb/Q5ZJX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM38", "url": "https://www.uniprot.org/uniprotkb/Q5ZJX4", "locus": { "chromosome": "20", "start_pos": 11957708, "end_pos": 11973730, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014948", "url": "https://www.ensembl.org/id/ENSGALG00010014948" } ] } } ], "crossref": [ { "id": "Q5ZJX4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZJX4", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"Protein Classification" ] }, { "id": "gga:768866", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768866", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFVQYPA", "url": "https://omabrowser.org/oma/group/TFVQYPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZJX4", "url": "https://www.orthodb.org/?gene=Q5ZJX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48024:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48024:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZJX4", "url": 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"https://www.uniprot.org/uniprotkb/Q5ZJX4/entry#Q5ZJX4-1", "sequence": { "sequence": "MHTVQKDTTFTKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSIQTGFTIGVQQLHPAFIQRPFGLTPHYVYPQAIIQPSVVIPTPVQSIASPYIDYTAASQAYSQYTTAAYDQYPYAASPAAGFVGYGYTGAVQPPITASTPAAPATAFVQYQPQQLQPDRMQ", "length": 215, "header": "sp|Q5ZJX4-1|RBM38_CHICK Isoform 1 of RNA-binding protein 38 OS=Gallus gallus OX=9031 GN=RBM38 PE=2 SV=1 CANONICAL=Q5ZJX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": 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The reference sequence was derived from JAENSK010000235.1. 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"MGPRRLPWARPGPALGLLLLALAGAVPAAGGSCSLLEEGNTIQKLHEDCFCYVQNRTMHLQYIWSTVQVKINSTRTFRFVPTPEKSNCRNSETVFEFAACAVQILWRPETSTETFLKIKQYGEDFCFRIQPFKEELYTVSMTREMLDGKLLFLFAAGIFLFHFANSLSRSTNFFYLSGIILGVLALLVFVLLALKRFIPRRSTFWILLSGCWMSSLYLIYCFKENMQWLWSEHRIYVLGYFVAVGTLSFATCYQHGPLTSELSITLFTWTLQLTAFVFIYCGVNIPQVAYAIIAVKPSPKGLGYPPAAAWHIGRKMKNHFQSKKVVVRCLTEEEYREQGETETVRALEELRSFCKNPDFSSWLAVSKLQSPHRFAGFVLGSPHVSPAETKAHDEEYGIGSSFLEEQLFETRTESEQDETTSYIHEGDDENEDEIHEPISFPYATELL", "length": 447, "header": "sp|Q5ZJY9-1|NEMP2_CHICK Isoform 1 of Nuclear envelope integral membrane protein 2 OS=Gallus gallus OX=9031 GN=NEMP2 PE=2 SV=1 CANONICAL=Q5ZJY9-1" }, "isoforms": [ { "isoform_ac": "Q5ZJY9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZJY9/entry#Q5ZJY9-1", "sequence": { "sequence": "MGPRRLPWARPGPALGLLLLALAGAVPAAGGSCSLLEEGNTIQKLHEDCFCYVQNRTMHLQYIWSTVQVKINSTRTFRFVPTPEKSNCRNSETVFEFAACAVQILWRPETSTETFLKIKQYGEDFCFRIQPFKEELYTVSMTREMLDGKLLFLFAAGIFLFHFANSLSRSTNFFYLSGIILGVLALLVFVLLALKRFIPRRSTFWILLSGCWMSSLYLIYCFKENMQWLWSEHRIYVLGYFVAVGTLSFATCYQHGPLTSELSITLFTWTLQLTAFVFIYCGVNIPQVAYAIIAVKPSPKGLGYPPAAAWHIGRKMKNHFQSKKVVVRCLTEEEYREQGETETVRALEELRSFCKNPDFSSWLAVSKLQSPHRFAGFVLGSPHVSPAETKAHDEEYGIGSSFLEEQLFETRTESEQDETTSYIHEGDDENEDEIHEPISFPYATELL", "length": 447, "header": "sp|Q5ZJY9-1|NEMP2_CHICK Isoform 1 of Nuclear envelope integral membrane protein 2 OS=Gallus gallus OX=9031 GN=NEMP2 PE=2 SV=1 CANONICAL=Q5ZJY9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, 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"UniProtKB", "id": "Q5ZJY9", "url": "https://www.uniprot.org/uniprotkb/Q5ZJY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZJY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 447, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZJY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZJY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000027.1. On Sep 23, 2021 this sequence version replaced NP_001026583.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026583" } ] }, { "annotation": "Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK09", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK09", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HIKESHI", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09", "locus": { "chromosome": "1", "start_pos": 190388412, "end_pos": 190397757, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009101", "url": "https://www.ensembl.org/id/ENSGALG00010009101" } ] } } ], "crossref": [ { "id": "Q5ZK09", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZK09", "database": 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"url": "https://www.uniprot.org/uniprotkb/Q5ZK09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZK09-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGCLVAGRLVQAAPQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFCYPDQSGMAVWQLLGFVTNEKPSAIFKISGLKSGKGSQHPFGAMNLPQTPTVAQIGISVELLENLVQQTPVANAAVSSVDSFTEFTQKMLDNFYNFASSFAVTQAQMTPNPSEAFIPANVVLKWYENFQRRLTQNPLFWKT", "length": 197, "header": "sp|Q5ZK09-1|HIKES_CHICK Isoform 1 of Protein Hikeshi OS=Gallus gallus OX=9031 GN=HIKESHI PE=2 SV=2 CANONICAL=Q5ZK09-1" }, "isoforms": [ { "isoform_ac": "Q5ZK09-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09/entry#Q5ZK09-1", "sequence": { "sequence": "MFGCLVAGRLVQAAPQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFCYPDQSGMAVWQLLGFVTNEKPSAIFKISGLKSGKGSQHPFGAMNLPQTPTVAQIGISVELLENLVQQTPVANAAVSSVDSFTEFTQKMLDNFYNFASSFAVTQAQMTPNPSEAFIPANVVLKWYENFQRRLTQNPLFWKT", "length": 197, "header": "sp|Q5ZK09-1|HIKES_CHICK Isoform 1 of Protein Hikeshi OS=Gallus gallus OX=9031 GN=HIKESHI PE=2 SV=2 CANONICAL=Q5ZK09-1" }, "locus": { "chromosome": "1", "start_pos": 190397693, "end_pos": 190389030, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021679.1", "url": "https://www.ensembl.org/id/ENSGALT00010021679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012369.1", "url": "https://www.ensembl.org/id/ENSGALP00010012369.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK09", "url": "https://www.uniprot.org/uniprotkb/Q5ZK09" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Full-length cDNAs from chicken 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"Centrosomal protein kizuna", "type": "recommended", "evidence": [ { "id": "Q5ZK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13/entry#names_and_taxonomy" } ] }, { "name": "Polo-like kinase 1 substrate 1", "type": "synonym", "evidence": [ { "id": "Q5ZK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein kizuna", "type": "synonym", "evidence": [ { "id": "NP_001006394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006394" } ] }, { "name": "polo-like kinase 1 substrate 1", "type": "synonym", "evidence": [ { "id": "NP_001006394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006394" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720271.1, SRR13267653.14866.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000060.1. On Jan 13, 2005 this sequence version replaced XP_419311.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006394" } ] }, { "annotation": "Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK13", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13#function" }, { "database": "UniProtKB", "id": "Q2M2Z5", "url": "https://www.uniprot.org/uniprotkb/Q2M2Z5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK13", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIZ", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13", "locus": { "chromosome": "3", "start_pos": 3777597, "end_pos": 3827102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018206", "url": "https://www.ensembl.org/id/ENSGALG00010018206" } ] } } ], "crossref": [ { 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"Protein" ] } ], "sequence": { "sequence": "MSEAGRAAAGPCPEVSPSRSQQLGGLLRCLRDSETRRLELERKLMEYKSSDAYLMKLKYVKLKKYLEEVNERQKRALLRNQTFLNEFNEFEAHVKASSSELIEKMVRYGREIKSGLSFQEGDLARGDKEEGCNEQMPQAARQAGIHAKTALSRSLHHPVPFFMGHCMSACSVQQETPQPAACPNSLTALQGDETDGHPTQADDDMQHANKLDEQGGKSYVPMGEKMSIRDSSLHSSLLNFTERKNSTELCSALPDGGSLQSRTADLASDTSVEEVVTREHLVASAKEVCEQPVLLASAPEPSITGPQCNLNTQQAASQDSSSSSTHPEENYSLQPPSCCAAEDEPLGSSVPEGFCSQDGSLKEDLEASEAAVLCQLPEAKSGQQWDVATLQASLNSHTAFLEEHEHLCTEELAAVLHSTLDLDEEAPGSQAPPLLREVLAEECGDGSSVQSNESSYSLPSIPNDSREVEQAKHVLWLDSMGKQGCVIGNNGSEAKESQEMCSERSSSSERSGDLSRPEFRKGAITAIKSKAFWGESDDSSSEAVDALRPQTRSPEADDFDDFYD", "length": 564, "header": "sp|Q5ZK13-1|KIZ_CHICK Isoform 1 of Centrosomal protein kizuna OS=Gallus gallus OX=9031 GN=KIZ PE=2 SV=1 CANONICAL=Q5ZK13-1" }, "isoforms": [ { "isoform_ac": "Q5ZK13-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK13/entry#Q5ZK13-1", "sequence": { "sequence": 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The reference sequence was derived from JAENSK010000087.1. On Dec 16, 2004 this sequence version replaced XP_424998.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008479" } ] }, { "annotation": "General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. 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"evidence": [ { "id": "Q5ZK63", "url": "https://omabrowser.org/oma/group/Q5ZK63/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P11031-1", "protein_name": "Activated RNA polymerase II transcriptional coactivator p15", "gene_name": "Sub1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL", "length": 127 }, "evidence": [ { "id": "Q5ZK63", "url": "https://omabrowser.org/oma/group/Q5ZK63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53999-1", "protein_name": "Activated RNA polymerase II transcriptional coactivator p15", "gene_name": "SUB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"name": "WD repeat-containing protein 71", "type": "synonym", "evidence": [ { "id": "NP_001026006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026006" }, { "id": "Q5ZK69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK69/entry#names_and_taxonomy" } ] }, { "name": "proteasomal ATPase-associated factor 1", "type": "synonym", "evidence": [ { "id": "NP_001026006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026006" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720215.1, HAEK01005387.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000032.1. On Sep 23, 2021 this sequence version replaced NP_001026006.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026006" } ] }, { "annotation": "Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZK69", "url": "https://www.uniprot.org/uniprotkb/Q5ZK69#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZK69", "url": "https://www.uniprot.org/uniprotkb/Q5ZK69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAAF1", "url": "https://www.uniprot.org/uniprotkb/Q5ZK69", "locus": { "chromosome": "1", "start_pos": 194850972, "end_pos": 194865950, "strand": "+", 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKB1-1", "uniprot_ac": "Q5ZKB1", "uniprot_id": "C42S1_CHICK", "mass": { "chemical_mass": 8840.0, "monoisotopic_mass": 8840.0 }, "refseq": { "ac": "NP_001383570", "name": "cDC42 small effector protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383570" }, "gene_names": [ { "name": "CDC42SE1", "type": "recommended", "evidence": [ { "id": "Q5ZKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ] }, { "name": "CDC42SE1", "type": "synonym", "evidence": [ { "id": "NP_001383570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383570" } ] }, { "name": "RCJMB04_11p12", "type": "synonym", "evidence": [ { "id": "Q5ZKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ] } ], "protein_names": [ { "name": "CDC42 small effector protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1/entry#names_and_taxonomy" } ] }, { "name": "cDC42 small effector protein 1", "type": "synonym", "evidence": [ { "id": "NP_001383570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383570" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720173.1, CD216532.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08016667 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD216532.1, JAENSK010000353.1, AJ445968.1, CD215193.1, CR524100.1 and AJ720173.1. On or before Oct 25, 2021 this sequence version replaced XP_003642732.1, XP_040546807.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383570" } ] }, { "annotation": "Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC42SE1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1", "locus": {} } ], "crossref": [ { "id": "Q5ZKB1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028119", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028119", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857323", "url": "https://www.ncbi.nlm.nih.gov/gene/100857323", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857323", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857323", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKB1", "url": "https://www.orthodb.org/?gene=Q5ZKB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13502:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13502:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKB1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKB1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001383570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKB1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDFWHKLGCCVVEKPQPKKRRRRIDRSMIGEPMNFVHLTHIGSGDMAAGEGLPMTGAVQEMRSKGGRERQWSSSRVL", "length": 78, "header": "sp|Q5ZKB1-1|C42S1_CHICK Isoform 1 of CDC42 small effector protein 1 OS=Gallus gallus OX=9031 GN=CDC42SE1 PE=3 SV=1 CANONICAL=Q5ZKB1-1" }, "isoforms": [ { "isoform_ac": "Q5ZKB1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1/entry#Q5ZKB1-1", "sequence": { "sequence": "MSDFWHKLGCCVVEKPQPKKRRRRIDRSMIGEPMNFVHLTHIGSGDMAAGEGLPMTGAVQEMRSKGGRERQWSSSRVL", "length": 78, "header": "sp|Q5ZKB1-1|C42S1_CHICK Isoform 1 of CDC42 small effector protein 1 OS=Gallus gallus OX=9031 GN=CDC42SE1 PE=3 SV=1 CANONICAL=Q5ZKB1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:100857323", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857323", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKB1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKB1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 78, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKB1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKB1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKB1" }, { "id": "PRU00057", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRIB", "eco_id": "ECO_0000255", "start_pos": 30, "end_pos": 43, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKD5-1", "uniprot_ac": "Q5ZKD5", "uniprot_id": "RRP12_CHICK", "mass": { "chemical_mass": 144053.0, "monoisotopic_mass": 144053.0 }, "refseq": {}, "gene_names": [ { "name": "RRP12", "type": "recommended", "evidence": [ { "id": "Q5ZKD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ] }, { "name": "RCJMB04_11j1", "type": "synonym", "evidence": [ { "id": "Q5ZKD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ] } ], "protein_names": [ { "name": "RRP12-like protein", "type": "recommended", "evidence": [ { "id": "Q5ZKD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Participates in the nucleoplasmic stage of pre-40S ribosomal subunit assembly, functioning as a scaffold for assembly factors and preparing pre-40S particles for export from the nucleus to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5#function" }, { "database": "UniProtKB", "id": "Q5JTH9", "url": "https://www.uniprot.org/uniprotkb/Q5JTH9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRP12", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5", "locus": { "chromosome": "6", "start_pos": 23153039, "end_pos": 23143174, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020730", "url": "https://www.ensembl.org/id/ENSGALG00010020730" } ] } } ], "crossref": [ { "id": "Q5ZKD5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "423845", "url": "https://www.ncbi.nlm.nih.gov/gene/423845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423845", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423845", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKD5", "url": "https://www.orthodb.org/?gene=Q5ZKD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKD5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKD5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKD5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARCGRLRAGTAAKLRRWRKGHSSDCNPETRRHRLAARSRFYSRPTEKSNLTVDAVKLHNELQSGSLRVERPSGSSQLPMEEGDAGEAATERSSGTFLSGLSDCTNVTFSRVQRFWESNSAAHKEICAVLAAVTDVIRSQGGKETETEYFAALMTTLEAVDSPESVAAVAYLLNLVLKRVPSPVLIKKFSDASKAFMNIISSQACSGSTSALRWVLSCLATLLRKQDLAAWSYPVTLQVYHGLLSFCVHTKPKVRKAAQHGVCSVLRGSEFMFGDEAPEHHPAAPSSAKFCVQEIEKAGGTKEATTTLHVLALLRDLLPCFPAAVLKTCCETLLRVMTLSHVLVTACAMQAFHSLFSAQPRTSCLPAELNAQIITALYDYVPSANDLQPLLTWLTTMERAHVNLGRLQKDLCWAHLPRLFSATMNCFLSPHLQVVAAAAQTLETLLNECIAPHMDELGNVSASTPAPGSYLCKMFRSVEEGLTYRFHAAWDGVLQVLEVFFEVCGKQCHPIMRKCLQSLCDLRLSPHFPYTTEVDQAVGAAVGAMGPEVLLEAVPLQIDGKEETLDFPRSWLLPVLRDYVQGARLGFFTSYFLPLAATLKSRALEFAQAGKSLESKIYDTLQWQVWTLLPGFCTRPTDVVEAFKGLARTLGMAISERPDLRPTVCQALRTLIHHGCGTDAERAEVGRFAKNFLPILFNVYSQPEEDGGSSSQRRSVLDTVRAYLTITDPQLGCGFLQKASEKLTSPESSEFARLSILDLVVAMSPYANEQALGSLYRTIQPSLQSKDHSMQKKAYRVLEEVCAAPHAPCQAFVHSHLEELQAVLLDSLKSAASPAKRPRLKCLFHIMKQLSAEHEPFVTALVPEVILCTKEVSVGARKNAFMLLVEMGHAFIRFGPTPQEAMERFLLLVYAGLTGSVTMISCTVLALTRLFFEFRDHMELNVVEQLLQNICLLLGSRTRDVVKAALGFIKVVLLLVDTTLLAKHVQTMLEAVGSLSDDMRRHFRMKLRNLFTKFIRKFGFELVQGLLPAEFHKVLVNIRKAEARSRKQRALRQAAAEAEEEEAPAQPKGDSMEEILADSEEEEEEEEERRRGKVRKKQARQKGQAWLKEGEEDEPLNFLDPNVSQRVLATEPSLKKSRGVKHDFQVSEDGRLIIHDEEEEVDNDEAKGVEEEVADVLQEVGLRSKKSQKRRFREEPDDDEPETGTYSQYRAGGSGIHRPLDKKPAFGAEYRSKKGKGDVKKKGQLDPYAYIPLNRAKLNKRKQAKMQGQFKGLMKGAQRGAKAGRKNRLKDRRP", "length": 1294, "header": "sp|Q5ZKD5-1|RRP12_CHICK Isoform 1 of RRP12-like protein OS=Gallus gallus OX=9031 GN=RRP12 PE=2 SV=1 CANONICAL=Q5ZKD5-1" }, "isoforms": [ { "isoform_ac": "Q5ZKD5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5/entry#Q5ZKD5-1", "sequence": { "sequence": 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"length": 1294, "header": "sp|Q5ZKD5-1|RRP12_CHICK Isoform 1 of RRP12-like protein OS=Gallus gallus OX=9031 GN=RRP12 PE=2 SV=1 CANONICAL=Q5ZKD5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", 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"id": "gga:423845", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423845", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKD5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKD5" } ], "pmid": "" } ] } ] }, 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"MENLVAGSTLPPLFADEDGSKEGSDVTVTGLAHSESSFTGGTSQPVNNPDLVEDLSQVQQLQNESTNTAENTEQKPEEEQQRTKRGGWAKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKRRYLDEADRDKERYMRELEQYQKTEAYKVFSRKAQDRQKGKLHRQDGARQPVHDHEKEADTKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQALTTSFAGVPLPGSGETPTMETIDSYMNRLHGIIMANPQENENLIATVRDVVNRLER", "length": 348, "header": "sp|Q5ZKF4-1|HM20A_CHICK Isoform 1 of High mobility group protein 20A OS=Gallus gallus OX=9031 GN=HMG20A PE=2 SV=1 CANONICAL=Q5ZKF4-1" }, "isoforms": [ { "isoform_ac": "Q5ZKF4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKF4/entry#Q5ZKF4-1", "sequence": { "sequence": "MENLVAGSTLPPLFADEDGSKEGSDVTVTGLAHSESSFTGGTSQPVNNPDLVEDLSQVQQLQNESTNTAENTEQKPEEEQQRTKRGGWAKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKRRYLDEADRDKERYMRELEQYQKTEAYKVFSRKAQDRQKGKLHRQDGARQPVHDHEKEADTKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQALTTSFAGVPLPGSGETPTMETIDSYMNRLHGIIMANPQENENLIATVRDVVNRLER", 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"MAALVRGLMRRVAALPQAVRSVSGGGQRHEPYRPLPITSPLAGLPRNFRVREPPKPQKVDRWTEKRALFGVYDNVGILGGFQIHPKHLIMGPKWLRGWRGNELQRCIRKKQMVGDRMFMDDYHNLKKRIRFLYKRFNRTGKHR", "length": 143, "header": "sp|Q5ZKG1-1|RM51_CHICK Isoform 1 of Large ribosomal subunit protein mL51 OS=Gallus gallus OX=9031 GN=MRPL51 PE=2 SV=1 CANONICAL=Q5ZKG1-1" }, "isoforms": [ { "isoform_ac": "Q5ZKG1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG1/entry#Q5ZKG1-1", "sequence": { "sequence": "MAALVRGLMRRVAALPQAVRSVSGGGQRHEPYRPLPITSPLAGLPRNFRVREPPKPQKVDRWTEKRALFGVYDNVGILGGFQIHPKHLIMGPKWLRGWRGNELQRCIRKKQMVGDRMFMDDYHNLKKRIRFLYKRFNRTGKHR", "length": 143, "header": "sp|Q5ZKG1-1|RM51_CHICK Isoform 1 of Large ribosomal subunit protein mL51 OS=Gallus gallus OX=9031 GN=MRPL51 PE=2 SV=1 CANONICAL=Q5ZKG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome 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"KGRKKTLENNTRQTARRFSSWRRNQPILSRLRQRPASESGVAPAESATPSSNLNGCREANRDGGWRSRPITAPEAGQTGVPLLARVRLTLPPPRVIDRWNEKRALFGVYDNIGILGDFEKHPKELIKGPVWLRGWRGNELQRCIRKKKMVGNRMFTEDLHNLNKRISYLYKHFNRHGKYR", "length": 180 }, "evidence": [ { "id": "Q5ZKG1", "url": "https://omabrowser.org/oma/group/Q5ZKG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKG1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 143, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKG1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKG1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKG2-1", "uniprot_ac": "Q5ZKG2", "uniprot_id": "BRD7_CHICK", "mass": { "chemical_mass": 74022.0, "monoisotopic_mass": 74022.0 }, "refseq": { "ac": "NP_001005839", "name": "bromodomain-containing protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005839" }, "gene_names": [ { "name": "BRD7", "type": "recommended", "evidence": [ { "id": "Q5ZKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ] }, { "name": "BRD7", "type": "synonym", "evidence": [ { "id": "NP_001005839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005839" } ] }, { "name": "RCJMB04_11a18", "type": "synonym", "evidence": [ { "id": "Q5ZKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ] } ], "protein_names": [ { "name": "Bromodomain-containing protein 7", "type": "recommended", "evidence": [ { "id": "Q5ZKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2/entry#names_and_taxonomy" } ] }, { "name": "bromodomain-containing protein 7", "type": "synonym", "evidence": [ { "id": "NP_001005839", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005839" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720122.1, HAEK01023763.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000248.1. On Sep 23, 2021 this sequence version replaced NP_001005839.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001005839", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005839" } ] }, { "annotation": "Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Participates in the Wnt signaling pathway. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Inhibits cell cycle progression from G1 to S phase (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRD7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2", "locus": { "chromosome": "11", "start_pos": 6168437, "end_pos": 6153820, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024063", "url": "https://www.ensembl.org/id/ENSGALG00010024063" } ] } } ], "crossref": [ { "id": "Q5ZKG2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415730", "url": "https://www.ncbi.nlm.nih.gov/gene/415730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415730", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKG2", "url": "https://www.orthodb.org/?gene=Q5ZKG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22881", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22881", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22881:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22881:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKG2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKG2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005839", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005839", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKG2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKHKKHKSDKHPYEEYVEKPLKLVLKVGGNEVAELSTGSAGLDSSLYEDKSEHEKHKDRKRKKRKKGEKQVPGEEKEKRKRKVKEDKRKRDREHPDSEGEQELRCQTPIRLELSPEKPLTSSLSKQEEVEQTPLQEALNQLMRQLQRKDPSSFFSFPVTDFIAPGYSMIIKNPMDFSTMKEKIKNNGYQSIEELKDNFKLMCTNAMTYNKPDTIYYKAAKKLLHSGMKILSQERIQSLKQSIEFMADLQKTRKQKDKVELQLSGEDESGSGKDKGEPVDGDTKAFKTPNKEHKKKDKDLLEDKLRINSLEREQEQIDRIVRESGGKLTRRLANSQCEFERRKPDGTTTLGLLNPVDLTAGEAGYCPVKLGMTAGRLQSGVNMLQGFKEDKRNKVTPVTYLNYGPYSSYAPTYDSTFANISKEDSDLIYSTYGEDSNQGSFSIHEFLMKSQDYPFLMADSLLDVLTKGGHSRSLRELETPLEEDEGPHERSDALKEIMEIDIAARLDSANNDRLTALKAVTNFGMPMEEFDSEEAEIFQRKLDETTKLLRELQDAQNERLSTKPPPNMICLLGPSYREMHLAERVTNNLKELAQQVTPGDIVSTYGIRKAMGISIPLPDIGDSGVDLTDEFQEPKKTVTITENECGPVTV", "length": 651, "header": "sp|Q5ZKG2-1|BRD7_CHICK Isoform 1 of Bromodomain-containing protein 7 OS=Gallus gallus OX=9031 GN=BRD7 PE=2 SV=1 CANONICAL=Q5ZKG2-1" }, "isoforms": [ { "isoform_ac": "Q5ZKG2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2/entry#Q5ZKG2-1", "sequence": { "sequence": "MGKKHKKHKSDKHPYEEYVEKPLKLVLKVGGNEVAELSTGSAGLDSSLYEDKSEHEKHKDRKRKKRKKGEKQVPGEEKEKRKRKVKEDKRKRDREHPDSEGEQELRCQTPIRLELSPEKPLTSSLSKQEEVEQTPLQEALNQLMRQLQRKDPSSFFSFPVTDFIAPGYSMIIKNPMDFSTMKEKIKNNGYQSIEELKDNFKLMCTNAMTYNKPDTIYYKAAKKLLHSGMKILSQERIQSLKQSIEFMADLQKTRKQKDKVELQLSGEDESGSGKDKGEPVDGDTKAFKTPNKEHKKKDKDLLEDKLRINSLEREQEQIDRIVRESGGKLTRRLANSQCEFERRKPDGTTTLGLLNPVDLTAGEAGYCPVKLGMTAGRLQSGVNMLQGFKEDKRNKVTPVTYLNYGPYSSYAPTYDSTFANISKEDSDLIYSTYGEDSNQGSFSIHEFLMKSQDYPFLMADSLLDVLTKGGHSRSLRELETPLEEDEGPHERSDALKEIMEIDIAARLDSANNDRLTALKAVTNFGMPMEEFDSEEAEIFQRKLDETTKLLRELQDAQNERLSTKPPPNMICLLGPSYREMHLAERVTNNLKELAQQVTPGDIVSTYGIRKAMGISIPLPDIGDSGVDLTDEFQEPKKTVTITENECGPVTV", "length": 651, "header": "sp|Q5ZKG2-1|BRD7_CHICK Isoform 1 of Bromodomain-containing protein 7 OS=Gallus gallus OX=9031 GN=BRD7 PE=2 SV=1 CANONICAL=Q5ZKG2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 598, "start_aa": "Thr", "end_pos": 598, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr598", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:415730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415730", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKG2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 651, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKG2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKG2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" }, { "id": "PRU00035", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000255", "start_pos": 131, "end_pos": 235, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZKG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG2" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear localization signal", "eco_id": "ECO_0000250", "start_pos": 65, "end_pos": 96, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 598 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 420, "end_pos": 422 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKG8-1", "uniprot_ac": "Q5ZKG8", "uniprot_id": "GET4_CHICK", "mass": { "chemical_mass": 34648.0, "monoisotopic_mass": 34648.0 }, "refseq": { "ac": "NP_001006159", "name": "Golgi to ER traffic protein 4 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159" }, "gene_names": [ { "name": "GET4", "type": "recommended", "evidence": [ { "id": "Q5ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8" } ] }, { "name": "C7orf20", "type": "synonym", "evidence": [ { "id": "NP_001006159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159" } ] }, { "name": "GET4", "type": "synonym", "evidence": [ { "id": "NP_001006159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159" } ] }, { "name": "RCJMB04_10o20", "type": "synonym", "evidence": [ { "id": "Q5ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8" } ] } ], "protein_names": [ { "name": "Golgi to ER traffic protein 4 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8/entry#names_and_taxonomy" } ] }, { "name": "Golgi to ER traffic protein 4 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720116.1, SRR13267659.203620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Jan 13, 2005 this sequence version replaced XP_414758.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159" } ] }, { "annotation": "As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8#function" }, { "database": "UniProtKB", "id": "Q7L5D6", "url": "https://www.uniprot.org/uniprotkb/Q7L5D6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GET4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8", "locus": { "chromosome": "14", "start_pos": 2192361, "end_pos": 2182874, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022259", "url": "https://www.ensembl.org/id/ENSGALG00010022259" } ] } } ], "crossref": [ { "id": "Q5ZKG8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "416450", "url": "https://www.ncbi.nlm.nih.gov/gene/416450", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416450", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416450", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKG8", "url": "https://www.orthodb.org/?gene=Q5ZKG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12875:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12875:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKG8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKG8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKG8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKG8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"ODR4_CHICK", "mass": { "chemical_mass": 49941.0, "monoisotopic_mass": 49941.0 }, "refseq": {}, "gene_names": [ { "name": "ODR4", "type": "recommended", "evidence": [ { "id": "Q5ZKH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ] }, { "name": "RCJMB04_10l22", "type": "synonym", "evidence": [ { "id": "Q5ZKH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ] } ], "protein_names": [ { "name": "Protein odr-4 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZKH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the trafficking of a subset of G protein coupled receptors.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ODR4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8", "locus": { "chromosome": "8", "start_pos": 10240924, "end_pos": 10262322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021504", "url": "https://www.ensembl.org/id/ENSGALG00010021504" } ] } } ], "crossref": [ { "id": "Q5ZKH8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "424455", "url": "https://www.ncbi.nlm.nih.gov/gene/424455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424455", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKH8", "url": "https://www.orthodb.org/?gene=Q5ZKH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33966:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33966:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKH8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKH8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKH8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLSVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKIVCRTYDVQDPKGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLSQGSSHRSTATVQVCSGSINLKGAVKCRAYVHNNKPKVKEAVLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMGVVIAVAVAVFASIFSFNYFSD", "length": 446, "header": "sp|Q5ZKH8-1|ODR4_CHICK Isoform 1 of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=2 SV=1 CANONICAL=Q5ZKH8-1" }, "isoforms": [ { "isoform_ac": "Q5ZKH8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8/entry#Q5ZKH8-1", "sequence": { "sequence": "MGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLSVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKIVCRTYDVQDPKGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLSQGSSHRSTATVQVCSGSINLKGAVKCRAYVHNNKPKVKEAVLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMGVVIAVAVAVFASIFSFNYFSD", "length": 446, "header": "sp|Q5ZKH8-1|ODR4_CHICK Isoform 1 of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=2 SV=1 CANONICAL=Q5ZKH8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424455", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKH8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKH8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 446, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKH8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKH8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKI4-1", "uniprot_ac": "Q5ZKI4", "uniprot_id": "CCD93_CHICK", "mass": { "chemical_mass": 71719.0, "monoisotopic_mass": 71719.0 }, "refseq": { "ac": "NP_001026433", "name": "coiled-coil domain-containing protein 93", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026433" }, "gene_names": [ { "name": "CCDC93", "type": "recommended", "evidence": [ { "id": "Q5ZKI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4" } ] }, { "name": "CCDC93", "type": "synonym", "evidence": [ { "id": "NP_001026433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026433" } ] }, { "name": "RCJMB04_10i21", "type": "synonym", "evidence": [ { "id": "Q5ZKI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 93", "type": "recommended", "evidence": [ { "id": "Q5ZKI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 93", "type": "synonym", "evidence": [ { "id": "NP_001026433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026433" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720100.1, HAEK01012657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Sep 23, 2021 this sequence version replaced NP_001026433.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026433" } ] }, { "annotation": "May be involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4#function" }, { "database": "UniProtKB", "id": "Q567U6", "url": "https://www.uniprot.org/uniprotkb/Q567U6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC93", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4", "locus": { "chromosome": "7", "start_pos": 28528094, "end_pos": 28495322, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020963", "url": "https://www.ensembl.org/id/ENSGALG00010020963" } ] } } ], "crossref": [ { "id": "Q5ZKI4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "424277", "url": "https://www.ncbi.nlm.nih.gov/gene/424277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424277", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKI4", "url": "https://www.orthodb.org/?gene=Q5ZKI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16441:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16441:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21673", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21673", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKI4", "url": 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} ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 617, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": 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The reference sequence was derived from JAENSK010000232.1. On Nov 4, 2021 this sequence version replaced NP_001026403.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026403" } ] }, { "annotation": "May act as a cation symporter.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ5#function" }, { "database": "UniProtKB", "id": "Q14CX5", "url": "https://www.uniprot.org/uniprotkb/Q14CX5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKJ5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC68A1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKJ5", "locus": {} } ], "crossref": [ { "id": "Q5ZKJ5", "url": 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"species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYSMD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0", "locus": { "chromosome": "Z", "start_pos": 60507731, "end_pos": 60503582, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013085", "url": "https://www.ensembl.org/id/ENSGALG00010013085" } ] } } ], "crossref": [ { "id": "Q5ZKK0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427106", "url": "https://www.ncbi.nlm.nih.gov/gene/427106", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427106", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKK0", "url": "https://www.orthodb.org/?gene=Q5ZKK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKK0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKK0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKK0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRGTGCSLQLPAGTQPPGGGHLYPGESEGPEEESEVFELRPRGREKVRRSTSRDRLDGIILLTKDIQEGDTLNAIALQYCCSVADIKRVNNLINDQDFFALRSIKIPVKKFSVLTETHVSPKGRTVLRPAHYSPEVQEASPDKFTANETAGNFLKEVDRDIEEIVKCNDTKRENLNEVVSALAAQQVCFETDGRSKKCKDPYYGADWGIGWWTAVVIMLIIGIVTPVFYLLYYEVLVKADVSHHSTMESAHSFVTAASHQKQIEHGRSPANSINVDSQGDIRPYNRKPQANVIHRHIT", "length": 300, "header": "sp|Q5ZKK0-1|LYSM3_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=LYSMD3 PE=2 SV=1 CANONICAL=Q5ZKK0-1" }, "isoforms": [ { "isoform_ac": "Q5ZKK0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0/entry#Q5ZKK0-1", "sequence": { "sequence": "MAGRGTGCSLQLPAGTQPPGGGHLYPGESEGPEEESEVFELRPRGREKVRRSTSRDRLDGIILLTKDIQEGDTLNAIALQYCCSVADIKRVNNLINDQDFFALRSIKIPVKKFSVLTETHVSPKGRTVLRPAHYSPEVQEASPDKFTANETAGNFLKEVDRDIEEIVKCNDTKRENLNEVVSALAAQQVCFETDGRSKKCKDPYYGADWGIGWWTAVVIMLIIGIVTPVFYLLYYEVLVKADVSHHSTMESAHSFVTAASHQKQIEHGRSPANSINVDSQGDIRPYNRKPQANVIHRHIT", "length": 300, "header": "sp|Q5ZKK0-1|LYSM3_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=LYSMD3 PE=2 SV=1 CANONICAL=Q5ZKK0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 149, "start_aa": "Asn", "end_pos": 149, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn149", "evidence": [ { "id": "Q5ZKK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 170, "start_aa": "Asn", "end_pos": 170, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn170", "evidence": [ { "id": "Q5ZKK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:427106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427106", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK0", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 300, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKK0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK0" }, { "id": "PRU01118", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000255", "start_pos": 64, "end_pos": 108, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 149, 170 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 170, "end_pos": 172 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 2 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_n_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 2 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_n_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKK2-1", "uniprot_ac": "Q5ZKK2", "uniprot_id": "INT9_CHICK", "mass": { "chemical_mass": 73763.0, "monoisotopic_mass": 73763.0 }, "refseq": { "ac": "NP_001026271", "name": "integrator complex subunit 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" }, "gene_names": [ { "name": "INTS9", "type": "recommended", "evidence": [ { "id": "Q5ZKK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ] }, { "name": "INT9", "type": "synonym", "evidence": [ { "id": "NP_001026271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] }, { "name": "INTS9", "type": "synonym", "evidence": [ { "id": "NP_001026271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] }, { "name": "RC74", "type": "synonym", "evidence": [ { "id": "NP_001026271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] }, { "name": "RCJMB04_10e20", "type": "synonym", "evidence": [ { "id": "Q5ZKK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 9", "type": "recommended", "evidence": [ { "id": "Q5ZKK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2/entry#names_and_taxonomy" } ] }, { "name": "Int9", "type": "synonym", "evidence": [ { "id": "Q5ZKK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2/entry#names_and_taxonomy" } ] }, { "name": "beta-lactamase fold protein family member RC-74", "type": "synonym", "evidence": [ { "id": "NP_001026271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] }, { "name": "integrator complex subunit 9", "type": "synonym", "evidence": [ { "id": "NP_001026271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720082.1, SRR13267661.1565.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000070.1. On Aug 8, 2005 this sequence version replaced XP_420031.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271" } ] }, { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2#function" }, { "database": "UniProtKB", "id": "Q9NV88", "url": "https://www.uniprot.org/uniprotkb/Q9NV88#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2", "locus": { "chromosome": "3", "start_pos": 105826380, "end_pos": 105895937, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010964", "url": "https://www.ensembl.org/id/ENSGALG00010010964" } ] } } ], "crossref": [ { "id": "Q5ZKK2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016631", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16294", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16294", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422023", "url": "https://www.ncbi.nlm.nih.gov/gene/422023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422023", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMKAVHC", "url": "https://omabrowser.org/oma/group/AMKAVHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKK2", "url": "https://www.orthodb.org/?gene=Q5ZKK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46094:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKK2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKK2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKK2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVLKFLQKF", "length": 658, "header": "sp|Q5ZKK2-1|INT9_CHICK Isoform 1 of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=2 SV=1 CANONICAL=Q5ZKK2-1" }, "isoforms": [ { "isoform_ac": "Q5ZKK2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2/entry#Q5ZKK2-1", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVLKFLQKF", "length": 658, "header": "sp|Q5ZKK2-1|INT9_CHICK Isoform 1 of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=2 SV=1 CANONICAL=Q5ZKK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422023", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1I9LM22-1", "protein_name": "Integrator complex subunit", "gene_name": "DSP4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MELTCLSKGDGFHYPPCHMLNLCGFRILIDCPLDLSAIKIFSPVPSGVGSEASEYLSDESLDAQNPIQKKQKLERQLTCADLVCEEPWYKTVKALHLWEASFIDIVLISNPMGLLGLPFLTQNPGFFAKIYMTEVTAKIGQLMMEDIVSMHKEFRCFHGPDNSSFPGWIKNLDSEQVPALLKKVVFGESGDDLGSWMRLYSLDDIESCMKKVQGVKFAEEVCYNGTLIIKALSSGLDIGACNWLINGPNGSLSYVSDSIFVSHHARSFDFHGLKETDVLIYSDFSSLQSAEVTEDGCISPDSDNNYISTISSDNKDSLLNTEDSLEEMEKLAFVCSCAAESADAGGSTLITITRIGIVLQLLELLSNSLESSSLKVPIFVISSVAEELLAYTNTIPEWLCEQRQEKLISGEPSFGHLKFIKNKKIHLFPAIHSPNLIYANRTSWQEPCIVFASHWSLRLGPSVQLLQRWRGDPKSLLVLEDGISSGLGLLPFRPIAMKILQCSFLSGIRLQKLPTLVSVLQPKIFLVPDAVNQRISLAAIKTISILNYFENKTLHVPRIVDNPSVEITTDLASKLSWRKLRQRESFGIARLKGGLLMEDGKHRLVSGLEQEESSGKARPLRHWGSVAPELLLDALLKMGIKGSIEQSTGDNGSEDKSIIHIENPNSGLIEFSEMGTAIITGDENVVSQVFQAIDGVLDGI", "length": 700 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8I6A4F2-1", "protein_name": "Integrator complex subunit 9", "gene_name": "Ints9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKEIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYRSIHGDFSHDFRQPCVLFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPKPTQPTSSKKRKRVSEDVPDSKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRFCAPRQLWMTAW", "length": 656 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54SH0-1", "protein_name": "Integrator complex subunit 9 homolog", "gene_name": "ints9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVHCLSQSAQSPCFLLEYKNVKILLDCALEISSILHFLPKNLNYNNNNNNNNNNNNNNNNNNNNNNNNNSYSFKEKDKELNQFFKNINGTLYIDNGCSNIKYNCPQFEMIDDFSTIDMILISNYTNIYALPFITEYTNFQGKIYATEPTVQIGKLLLEELVQMDKQYSNSSINNNNNNNNLSDCWQNIEILEKLNVHNVGMENENLYRDSYRWKDLYKKIDIEKSFEKIQSIRFNESIKHYGFECIPSSSGYGLGSANWVIESKGFERVVYISDSSLSLSRYPTPFQLSPIDNPDVLILSKINHYPNNPPDQMLSELCSNIGSTLQQGGTVLIPSYSCGIILDLFEHLADYLNKVGLPYVPIYFVSSVSKAVLSYADIYSEWLNKSKQERAFMPETPFLHQDLMRKGQFQAYQHVHSNFQANDPCIIFTGHPSCRIGDITTLIKLYDNPKNSILLIEPDFDFKSTVLPFSKQISRIQFLPIDPRINFNEANLLISKLSPKHLIIPRIYKNYVKNKHSNGNFGIVTTILPLDTIKIQNNQNFESGFIDKELAQTIQTKVLDKSSQLKNNTTTTTTTTINNQQPIHVAEISGVLSMSDHELIISPPNISDSNKIIHIKEKFIWGTLSIENIIKAINSTKQFKNNGDSIEYFEINENYYLIKISSKNKTNNNNNSDQVTNIHLSPQNVNIETSCETTRRLISDIVLLNCNGFYV", "length": 712 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K114-1", "protein_name": "Integrator complex subunit 9", "gene_name": "Ints9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTMQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNIPFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYRSIHGDFSNDFRQPCVLFTGHPSLRFGDVVHFMELWGKSSLNTIIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQAHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPKPTQPTSSKKRKRVNEDIPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDETLRVRLRDLVLRFLQKF", "length": 658 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95TS5-1", "protein_name": "Integrator complex subunit 9", "gene_name": "IntS9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLYCLSGDLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDPQMDGELKDCCGRVFVDSTPEFNLPMDKMLDFSEVDVILISNYLNMLALPYITENTGFKGKVYATEPTLQIGRFFLEELVDYIEVSPKACTARLWKEKLHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKVTIMGYDEKLDILGAFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSALKHADVLIMTGLTQAPTVNPDTKLGELCMNVALTIRNNGSALIPCYPSGVVYDLFECLTQNLENAGLNNVPMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEGFSKDFRQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPFQPLAMKAFYCPIDTSLNYQQANKLIKELKPNVLVIPEAYTKPHPSAPNLFIEQPDKKIITFKCGEIIRLPLKRKLDRIYITSELAQKISPKEVAAGVTFSTLTGVLQVKDKVHCIQPCADSVKDETISSNSAPTKEDVLKNVKYEYGSIDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHIICGGKPTTRLKLRDTIMKCLQSF", "length": 654 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9NV88-1", "protein_name": "Integrator complex subunit 9", "gene_name": "INTS9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSSVPLYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHLLQPPPRPAQPTSGKKRKRVSDDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDLVLKFLQKF", "length": 658 }, "evidence": [ { "id": "Q5ZKK2", "url": "https://omabrowser.org/oma/group/Q5ZKK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "id": "GO:0090101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090101", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "regulation of cellular response to growth factor stimulus", "id": "GO:0090287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090287", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKK2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKK2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 658, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKK2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKK2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKK2" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear localization signal", "eco_id": "ECO_0000250", "start_pos": 566, "end_pos": 570, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKL5-1", "uniprot_ac": "Q5ZKL5", "uniprot_id": "PPCEL_CHICK", "mass": { "chemical_mass": 84313.0, "monoisotopic_mass": 84313.0 }, "refseq": { "ac": "NP_001026224", "name": "prolyl endopeptidase-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224" }, "gene_names": [ { "name": "PREPL", "type": "recommended", "evidence": [ { "id": "Q5ZKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ] }, { "name": "PREPL", "type": "synonym", "evidence": [ { "id": "NP_001026224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224" } ] }, { "name": "RCJMB04_10c4", "type": "synonym", "evidence": [ { "id": "Q5ZKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ] } ], "protein_names": [ { "name": "Prolyl endopeptidase-like", "type": "recommended", "evidence": [ { "id": "Q5ZKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "Q5ZKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5/entry#names_and_taxonomy" } ] }, { "name": "Prolylendopeptidase-like", "type": "synonym", "evidence": [ { "id": "Q5ZKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5/entry#names_and_taxonomy" } ] }, { "name": "prolyl endopeptidase-like", "type": "synonym", "evidence": [ { "id": "NP_001026224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224" } ] }, { "name": "prolylendopeptidase-like", "type": "synonym", "evidence": [ { "id": "NP_001026224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720069.1, SRR13267654.58721.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720069.1. On Aug 8, 2005 this sequence version replaced XP_419461.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224" } ] }, { "annotation": "Serine peptidase whose precise substrate specificity remains unclear (By similarity). Does not cleave peptides after a arginine or lysine residue (By similarity). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (By similarity). May play a role in the regulation of synaptic vesicle exocytosis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5#function" }, { "database": "UniProtKB", "id": "Q4J6C6", "url": "https://www.uniprot.org/uniprotkb/Q4J6C6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PREPL", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5", "locus": { "chromosome": "3", "start_pos": 25163334, "end_pos": 25198270, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020443", "url": "https://www.ensembl.org/id/ENSGALG00010020443" } ] } } ], "crossref": [ { "id": "Q5ZKL5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "421405", "url": "https://www.ncbi.nlm.nih.gov/gene/421405", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421405", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421405", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKL5", "url": "https://www.orthodb.org/?gene=Q5ZKL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11757:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11757:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKL5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKL5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKL5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCWTAKSFVRWLSSSVKYYPKDNHLQALCLCTKTKLNKCHILDWSRSPCNSAVPPGRILSWRLFSCKEGTKDLCKREKIASVTASELLYKDLLKSEQENWNKISRSYKAMTKRIKEKIEELHNKYTLHLESPRMRFGGNVYFEENGYILCSKADDDKGNVHILFSTEDMGFSGAYIKRIRISPDERYLATSLQSENSEEATCVIMKLGDVPFVEEVIPNVFSFEWATNDVLYYTSQKNLKCQNVFMTTFTNEKYTKLVYTEQDARFFVDIYCTKDRRFLTINSNSKTTSEVWLIDCRHPFKLPVLVQARTKGVIYHVEHRNNELYILTSYGEPAEYKLMKASVASTGMENWQLVYALEEKTKLIDLEMFRDHCIMFLQKAGYLYLNVIAFVSHSVQSIQLPTWACAFELESHPEHASSTCYFQLTSPVHPPRRFAYSFKENNLIEQAAEEVPIIMNCHTTRLLAKSKDETLVPITVFHNVNSKELHRKPLLVHVYGAYGIDLNMSFKEEKLMLIEEGWILAYCHVRGGGELGLRWHKDGCQQNKLKGLHDLKACIMLLHELGFSQPKYTALTAVSAGGVLAGAICNSDPELIRAVVLQAPFVDVLNTMMKTHLPLSIEEQEEWGNPLADEKCMKYIKNYCPYHNIKPQCYPSVFITAYENDQRVPLTGILRYVQKLRKATLDHASRTRKKGNWIPNIILDIQASGSHCDSSWEDSLNEVARHLAFLKKELQV", "length": 732, "header": "sp|Q5ZKL5-1|PPCEL_CHICK Isoform 1 of Prolyl endopeptidase-like OS=Gallus gallus OX=9031 GN=PREPL PE=2 SV=1 CANONICAL=Q5ZKL5-1" }, "isoforms": [ { "isoform_ac": "Q5ZKL5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5/entry#Q5ZKL5-1", "sequence": { "sequence": "MCWTAKSFVRWLSSSVKYYPKDNHLQALCLCTKTKLNKCHILDWSRSPCNSAVPPGRILSWRLFSCKEGTKDLCKREKIASVTASELLYKDLLKSEQENWNKISRSYKAMTKRIKEKIEELHNKYTLHLESPRMRFGGNVYFEENGYILCSKADDDKGNVHILFSTEDMGFSGAYIKRIRISPDERYLATSLQSENSEEATCVIMKLGDVPFVEEVIPNVFSFEWATNDVLYYTSQKNLKCQNVFMTTFTNEKYTKLVYTEQDARFFVDIYCTKDRRFLTINSNSKTTSEVWLIDCRHPFKLPVLVQARTKGVIYHVEHRNNELYILTSYGEPAEYKLMKASVASTGMENWQLVYALEEKTKLIDLEMFRDHCIMFLQKAGYLYLNVIAFVSHSVQSIQLPTWACAFELESHPEHASSTCYFQLTSPVHPPRRFAYSFKENNLIEQAAEEVPIIMNCHTTRLLAKSKDETLVPITVFHNVNSKELHRKPLLVHVYGAYGIDLNMSFKEEKLMLIEEGWILAYCHVRGGGELGLRWHKDGCQQNKLKGLHDLKACIMLLHELGFSQPKYTALTAVSAGGVLAGAICNSDPELIRAVVLQAPFVDVLNTMMKTHLPLSIEEQEEWGNPLADEKCMKYIKNYCPYHNIKPQCYPSVFITAYENDQRVPLTGILRYVQKLRKATLDHASRTRKKGNWIPNIILDIQASGSHCDSSWEDSLNEVARHLAFLKKELQV", "length": 732, "header": "sp|Q5ZKL5-1|PPCEL_CHICK Isoform 1 of Prolyl endopeptidase-like OS=Gallus gallus OX=9031 GN=PREPL PE=2 SV=1 CANONICAL=Q5ZKL5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421405", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421405", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKL5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 732, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKL5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKL5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 503, "end_pos": 505 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKL7-1", "uniprot_ac": "Q5ZKL7", "uniprot_id": "BIN2_CHICK", "mass": { "chemical_mass": 51180.0, "monoisotopic_mass": 51180.0 }, "refseq": { "ac": "NP_001074365", "name": "bridging integrator 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074365" }, "gene_names": [ { "name": "BIN2", "type": "recommended", "evidence": [ { "id": "Q5ZKL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ] }, { "name": "BIN2", "type": "synonym", "evidence": [ { "id": "NP_001074365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074365" } ] }, { "name": "RCJMB04_10b19", "type": "synonym", "evidence": [ { "id": "Q5ZKL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ] } ], "protein_names": [ { "name": "Bridging integrator 2", "type": "recommended", "evidence": [ { "id": "Q5ZKL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7/entry#names_and_taxonomy" } ] }, { "name": "bridging integrator 2", "type": "synonym", "evidence": [ { "id": "NP_001074365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074365" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720067.1, SRR13267649.286124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000492.1. On Sep 23, 2021 this sequence version replaced NP_001074365.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001074365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074365" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BIN2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7", "locus": { "chromosome": "34", "start_pos": 2271735, "end_pos": 2262249, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023819", "url": "https://www.ensembl.org/id/ENSGALG00010023819" } ] } } ], "crossref": [ { "id": "Q5ZKL7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07612", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07612", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "777552", "url": "https://www.ncbi.nlm.nih.gov/gene/777552", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:777552", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:777552", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKL7", "url": "https://www.orthodb.org/?gene=Q5ZKL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKL7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKL7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001074365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKL7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGKSGAGLFAKQVQKHFSRAQEKVLQKLGKTVETKDEQFEQSAYNFQLQQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQVVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWEPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSGESREIDLSPKEMEVSAGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPEQDVSCNPPQDPSESLTPL", "length": 476, "header": "sp|Q5ZKL7-1|BIN2_CHICK Isoform 1 of Bridging integrator 2 OS=Gallus gallus OX=9031 GN=BIN2 PE=2 SV=1 CANONICAL=Q5ZKL7-1" }, "isoforms": [ { "isoform_ac": "Q5ZKL7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7/entry#Q5ZKL7-1", "sequence": { "sequence": "MAEGKSGAGLFAKQVQKHFSRAQEKVLQKLGKTVETKDEQFEQSAYNFQLQQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQVVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWEPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSGESREIDLSPKEMEVSAGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPEQDVSCNPPQDPSESLTPL", "length": 476, "header": "sp|Q5ZKL7-1|BIN2_CHICK Isoform 1 of Bridging integrator 2 OS=Gallus gallus OX=9031 GN=BIN2 PE=2 SV=1 CANONICAL=Q5ZKL7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:777552", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:777552", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" }, { "name": "podosome assembly", "id": "GO:0071800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071800", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKL7", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKL7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 476, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKL7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKL7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKL7" }, { "id": "PRU00361", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAR", "eco_id": "ECO_0000255", "start_pos": 26, "end_pos": 242, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKN3-1", "uniprot_ac": "Q5ZKN3", "uniprot_id": "PHTF2_CHICK", "mass": { "chemical_mass": 85452.0, "monoisotopic_mass": 85452.0 }, "refseq": { "ac": "NP_001006226", "name": "protein PHTF2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006226" }, "gene_names": [ { "name": "PHTF2", "type": "recommended", "evidence": [ { "id": "Q5ZKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3" } ] }, { "name": "PHTF2", "type": "synonym", "evidence": [ { "id": "NP_001006226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006226" } ] }, { "name": "RCJMB04_9p2", "type": "synonym", "evidence": [ { "id": "Q5ZKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3" } ] } ], "protein_names": [ { "name": "Protein PHTF2", "type": "recommended", "evidence": [ { "id": "Q5ZKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3/entry#names_and_taxonomy" } ] }, { "name": "protein PHTF2", "type": "synonym", "evidence": [ { "id": "NP_001006226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006226" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720051.1, SRR13267659.10447.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Sep 20, 2021 this sequence version replaced NP_001006226.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKN3", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHTF2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3", "locus": { "chromosome": "1", "start_pos": 12638984, "end_pos": 12702068, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009371", "url": "https://www.ensembl.org/id/ENSGALG00010009371" } ] } } ], "crossref": [ { "id": "Q5ZKN3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417728", "url": "https://www.ncbi.nlm.nih.gov/gene/417728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417728", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKN3", "url": "https://www.orthodb.org/?gene=Q5ZKN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKN3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKN3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKN3", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKN3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKVTDARDWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTGHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVVFFPFFYRWWLQVTSRVIFFWLLVLYLLQVAAVVLFCTAQSPHNIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPPSTGVKRRRKLRKAAHLEVHREGDGSSTTDNTQEGTVQSYGTSTSYSIGAVFRDIWHAAFFLSGSKKAKNSIDKSTETDNGYVSLEGKKTGKSSEECAQAQERLCEVIKPEESGWSTTTMRETFGTPSHHKETHRTVTNLSDEVSSEEGPETGYSLRRNVERTSSDGTLRNRKSHHYKKHYPLEDTPKSGTSCSSRCSSSRQDSESTRPESETEDVWEDLLHCAECHSSCTSETDVESPQMNPCVKKEYRDDPFHQSHLPWIHSLNPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSYIPGIGYQIFGNIISLILGLMPFVFRLSQAKDLEQLAAHSATELCITAFGSNGDILVLSMVVISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHMHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS", "length": 752, "header": "sp|Q5ZKN3-1|PHTF2_CHICK Isoform 1 of Protein PHTF2 OS=Gallus gallus OX=9031 GN=PHTF2 PE=2 SV=1 CANONICAL=Q5ZKN3-1" }, "isoforms": [ { "isoform_ac": "Q5ZKN3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3/entry#Q5ZKN3-1", "sequence": { "sequence": "MASKVTDARDWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTGHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVVFFPFFYRWWLQVTSRVIFFWLLVLYLLQVAAVVLFCTAQSPHNIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPPSTGVKRRRKLRKAAHLEVHREGDGSSTTDNTQEGTVQSYGTSTSYSIGAVFRDIWHAAFFLSGSKKAKNSIDKSTETDNGYVSLEGKKTGKSSEECAQAQERLCEVIKPEESGWSTTTMRETFGTPSHHKETHRTVTNLSDEVSSEEGPETGYSLRRNVERTSSDGTLRNRKSHHYKKHYPLEDTPKSGTSCSSRCSSSRQDSESTRPESETEDVWEDLLHCAECHSSCTSETDVESPQMNPCVKKEYRDDPFHQSHLPWIHSLNPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSYIPGIGYQIFGNIISLILGLMPFVFRLSQAKDLEQLAAHSATELCITAFGSNGDILVLSMVVISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHMHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS", "length": 752, "header": "sp|Q5ZKN3-1|PHTF2_CHICK Isoform 1 of Protein PHTF2 OS=Gallus gallus OX=9031 GN=PHTF2 PE=2 SV=1 CANONICAL=Q5ZKN3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "Q5ZKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 664, "start_aa": "Asn", "end_pos": 664, "end_aa": "Asn", "residue": "Asn", "site_lbl": 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"url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKN3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN3" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHTF", "eco_id": "ECO_0000255", "start_pos": 6, "end_pos": 153, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 296, 664, 723 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 723, "end_pos": 725 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 3 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"MEPERLRRRLGSAFRVRGLLLRAEAVKYLTETLESLNEEEFEDVIDKIIDAVEKQPLSTNMIELSTVEAAVQECSQALDETIKNVFNIIGAFDIPRYIYNPDRKRFVPLSMTNLPVPNLFGTARDKAELFRERYSILQQRTHRHELFTPAAVVIHPDDNRSKFQLKTVETLLGNTAKVREVIVLGMITQLKEGKYFLEDPTGVVQLDLSKAQFHSGLYTESCFVLAEGWYEDEVFHVNAFGFPPTEPSATTRAFYGNINFFGGPSSASVKASAKLKQLEDENEDAMFVFLSDVWLDQAEVLEKLHTMFSGYSSAPPTCFFFCGNFSSAPYGKNQIQSLKGSLKALADIICEYPSIHKSSRFVFVPGPEDPGPGSVLPRPPLAENITQEFRQLVPFSVFTTNPCRVQYCTQEIIIFREDLVNKMCRNCVRFPSSSMDIPNHFVKTILSQGHLTPLPLYVSPVYWAYDYALRVYPVPDMLVIADKYDPFTVTNTDCLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGL", "length": 527, "header": "sp|Q5ZKQ6-1|DPOE2_CHICK Isoform 1 of DNA polymerase epsilon subunit 2 OS=Gallus gallus OX=9031 GN=POLE2 PE=2 SV=1 CANONICAL=Q5ZKQ6-1" }, "isoforms": [ { "isoform_ac": "Q5ZKQ6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6/entry#Q5ZKQ6-1", "sequence": { "sequence": 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Wakasugi Mitsuo, Ishigaki Yasuhito, Nikaido Osamu, Matsunaga Tsukasa", "evidence": [ { "database": "Reactome", "id": "R-GGA-353303", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353303" } ], "reference": [ { "type": "PubMed", "id": "12773817", "url": "https://glygen.org/publication/PubMed/12773817" } ] }, { "title": "DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Ishiai M, Kimura M, Namikoshi K, Yamazoe M, Yamamoto K, Arakawa H, Agematsu K, Matsushita N, Takeda S, Buerstedde JM, Takata M", "evidence": [ { "database": "Reactome", "id": "R-GGA-353303", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353303" } ], "reference": [ { "type": "PubMed", "id": "15572677", "url": "https://glygen.org/publication/PubMed/15572677" } ] }, { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKQ6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6" }, { "database": "Reactome", "id": "R-GGA-353303", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353303" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Molecular cloning of human XPAC gene homologs from chicken, Xenopus laevis and Drosophila melanogaster.", "journal": "Biochemical and biophysical research communications", "date": "1991-12-31", "authors": "Shimamoto T, Kohno K, Tanaka K, Okada Y", "evidence": [ { "database": "Reactome", "id": "R-GGA-353303", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353303" } ], "reference": [ { "type": "PubMed", "id": "1764072", "url": "https://glygen.org/publication/PubMed/1764072" } ] } ], "pathway": [ { "id": "gga:423567", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423567", "resource": "KEGG Pathway" }, { "id": "R-GGA-353303", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-353303", "resource": "Reactome", "description": "Nucleotide Excision Repair" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "epsilon DNA polymerase complex", "id": "GO:0008622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008622", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKQ6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKQ6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKQ6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKQ6", "url": "https://www.uniprot.org/uniprotkb/Q5ZKQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKQ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 527, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKQ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKQ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 516, "end_pos": 518 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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] }, { "uniprot_canonical_ac": "Q5ZKT1-1", "uniprot_ac": "Q5ZKT1", "uniprot_id": "TBCC1_CHICK", "mass": { "chemical_mass": 62099.0, "monoisotopic_mass": 62099.0 }, "refseq": { "ac": "NP_001006545", "name": "TBCC domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006545" }, "gene_names": [ { "name": "TBCCD1", "type": "recommended", "evidence": [ { "id": "Q5ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ] }, { "name": "RCJMB04_9e22", "type": "synonym", "evidence": [ { "id": "Q5ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ] }, { "name": "TBCCD1", "type": "synonym", "evidence": [ { "id": "NP_001006545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006545" } ] } ], "protein_names": [ { "name": "TBCC domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1/entry#names_and_taxonomy" } ] }, { "name": "TBCC domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006545" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720003.1, SRR13267649.229988.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720003.1. On Jan 13, 2005 this sequence version replaced XP_422683.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006545" } ] }, { "annotation": "May play a role in the regulation of centrosome and Golgi apparatus positioning.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBCCD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1", "locus": { "chromosome": "9", "start_pos": 4010829, "end_pos": 4019192, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024585", "url": "https://www.ensembl.org/id/ENSGALG00010024585" } ] } } ], "crossref": [ { "id": "Q5ZKT1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006566", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006566", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424869", "url": "https://www.ncbi.nlm.nih.gov/gene/424869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424869", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VPNAWDQ", "url": "https://omabrowser.org/oma/group/VPNAWDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKT1", "url": "https://www.orthodb.org/?gene=Q5ZKT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16052:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16052:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKT1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKT1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKT1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVSLWPRTEPLLLGALPVPPPARLGPHYLRKMAAYARARAAEGCYPRLSWPRWRHIACGKLQLGRGLAWLYFERFHDLLPPPDPPRRLQRAEAEAACGSAEELERERGKLSVDTLRFLLFLYLQQLNKASLRTSLIGEEWPSHRARAAGLPGRAAGQSKNWNDQDHLAFLLTHLSDMLELLLEPEQLGASSHATHNSLVSYEAVCALSFLIEGTVNNSRTIHPLHELALWQPCHGQNGYSKISKTFSFPKLENWLRSCLIINPFGMTACLRSGKKLAWAQQVEGTTRRAKIACNTRVVPEVSPMVIMSQVYKQTLAKSSDTLVGAHVRIHRCNESFIYLLSPLCSVTIEKCRNSTFVLGPVEASVHVHSCDNIKVITVCHCLSLSSTTGCTFHILTPTQPLILAGNQAISFAPFHTHYPMLEDHMAQVGLATVPNYWDSPMMVCKEGSDASVFRLLSPLDFYTFVIPFEMEGDTTETPGGLPHAYQKALNQREQKVQIWQKMVKEACLTKDQRKQFQMLVESKFYEWLIQTGNRQQLDSLVPPAVGSKQAAG", "length": 555, "header": "sp|Q5ZKT1-1|TBCC1_CHICK Isoform 1 of TBCC domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TBCCD1 PE=2 SV=1 CANONICAL=Q5ZKT1-1" }, "isoforms": [ { "isoform_ac": "Q5ZKT1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1/entry#Q5ZKT1-1", "sequence": { "sequence": "MAAAVSLWPRTEPLLLGALPVPPPARLGPHYLRKMAAYARARAAEGCYPRLSWPRWRHIACGKLQLGRGLAWLYFERFHDLLPPPDPPRRLQRAEAEAACGSAEELERERGKLSVDTLRFLLFLYLQQLNKASLRTSLIGEEWPSHRARAAGLPGRAAGQSKNWNDQDHLAFLLTHLSDMLELLLEPEQLGASSHATHNSLVSYEAVCALSFLIEGTVNNSRTIHPLHELALWQPCHGQNGYSKISKTFSFPKLENWLRSCLIINPFGMTACLRSGKKLAWAQQVEGTTRRAKIACNTRVVPEVSPMVIMSQVYKQTLAKSSDTLVGAHVRIHRCNESFIYLLSPLCSVTIEKCRNSTFVLGPVEASVHVHSCDNIKVITVCHCLSLSSTTGCTFHILTPTQPLILAGNQAISFAPFHTHYPMLEDHMAQVGLATVPNYWDSPMMVCKEGSDASVFRLLSPLDFYTFVIPFEMEGDTTETPGGLPHAYQKALNQREQKVQIWQKMVKEACLTKDQRKQFQMLVESKFYEWLIQTGNRQQLDSLVPPAVGSKQAAG", "length": 555, "header": "sp|Q5ZKT1-1|TBCC1_CHICK Isoform 1 of TBCC domain-containing protein 1 OS=Gallus gallus OX=9031 GN=TBCCD1 PE=2 SV=1 CANONICAL=Q5ZKT1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424869", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480MDB5-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "TBCCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQSGVLLWVKAEPFIVGALQVPPPSKFSLHYLRKISSYVRTRATEGGYPRLSWSTWRHIACGKLQLAKDLAWLYFEIFDSLTVKTPEERLEWSEILSNCMSGDEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLIGEEWPSPRHRSQSPDLTEKSSCHNKNWNDYSHQAFVCDHLSDLLELLLDPEQLTASFHSTHSSLVSREAVVALSFLIEGTVSGARKIYPLYELALWQPLHAETGFSKTSKAFSFYKLEAWLRASLTGNPFGTSACLKSGKKLAWAHQVEGTTKRAKIACNTHVAPRMYRMVVMSQVYKQTLAKSSDTLVGAHVKIHRCNESFIYLLSPLRSVTVEKCRNSTFVLGPVQTALHLHSCDNVKVIAVCHRLSISSTTDCIFHILTPTRPLILSGNQRVTFAPFHTHYPMLEDHMARTGLAAVPNYWDNPMIVCRENSNTSVFRLLPPCDFYVFIIPFEMEGDTTEIPGGLPSAYQRALGQREKKIQIWQKTVKEARLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVPPTVGSKQAAG", "length": 557 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N5E5-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "Tbccd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQSRVFLWVKAEPFIVGALQVPPPSKFSLHYLRKIATYVRTRATEGAYPRLYWSTWRHIACGKLQLAKELAWLYFEIFDNLSVRTPEERLEWSEILSNCMTEDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSLIGEEWPSPRSRPQSPSLTERPSCHNKNWNDYSHQAFVCDHLLDLLELLLEPEQLTASFHSTHSSVVSREAVLALSFLIEGTVSRTRKVYPLHELAMWQPLHADSGFSKISKTFSFYKLEAWLRTCLTANPFGPSACLKSGKKLAWAHQVEGATKRAKIACNTHVAPQMHRMVVMSQVYKQTLAKSSDTLVGAHIRVHRCNESFIYLLSPLRSVTIEKCRNTTFVLGPVETALHLQDCENLKIIAVCHRLSISSTTDCTFHVMTPSRPLILSGNQSVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCRESSDTRVFRLLPPCEFYIFIIPFEMEGDTAEIPGGLPSAYQKVLAQRERKIQIWQKTVKEARLTKEQRKQFQVLVENKFYEWLINTGHRQQLDSLVPHAAASKQEPG", "length": 557 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A4QP31-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "tbccd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKYTAYVWPRLEPFLVGVLPATPPSKFSMHYLRKMASYVRTRDGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEALSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLIGEEWPSPRSRSPSSSSSERDAKISSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQVEGTLKKAKIFRNTHAAPPGSRLVLMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPGNASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCEIPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPTITPSSSAEHWSSNQNTLKEQTHEQPTGTVC", "length": 582 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5FVR8-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "Tbccd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQSGVLLWVKAEPFIVGALQEPPPSKLSLHYLKKVAAYVRTRATERAYPRLYWPTWRHIACGKLQLAKDLAWLYFEIFDNLSERTPEERLEWSEILSNCTTKDEVEKQRNQLSVDTLQFLLFLYIQQLNKISLRTSFIGEEWPSPRNRPKSPSPAERSSCHNKNWNDYNHQAFVCDHLSELLELLLDPEQLTESFHSTQSSLLSREAVTALSFLIEGTVSRTKKVYPLHELALWQPLHAANGFSKISKTFSLYKLEAWLRACLTTNPFGLSACLQSGKKLAWAHKVEGATKRAKIACNAHMAPRSHRIVVMSQVCNQTLAKSSETLVGAHVRAHRCNESFIYLLSPLRSMTIEKCRNSTFVLGPVETALHLHGCENLKVIAVCHRLSVSSTIGCTFHIMTPSRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDDPMVLGGEGTDTRVFQLLPPSEFYVFVTPFEMEGDTAEIPGGLPPAYQKALAHREQRIHNWQKTVKEARLTKEQRKQFQVLVENKFYEWLVSTGHRQQLDSLVPPPAASNQVAKKDLTWSHGALET", "length": 569 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q640P7-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "Tbccd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQSGVLLWVKAEPFLVGALQEPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFEMFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLIGEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAWAHQVEGSTKRAKIACNAHMAPRLHRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPTPAAS", "length": 552 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVR7-1", "protein_name": "TBCC domain-containing protein 1", "gene_name": "TBCCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQSRVLLWVKAEPFIVGALQVPPPSKFSLHYLRKISTYVQIRATEGAYPRLYWSTWRHIACGKLQLAKDLAWLYFEIFDSLSMKTPEERLEWSEVLSNCMSEEEVEKQRNQLSVDTLQFLLFLYIQQLNKVSLRTSLIGEEWPSPRNKSQSPDLTEKSNCHNKNWNDYSHQAFVYDHLSDLLELLLDPKQLTASFHSTHSSLVSREAVVALSFLIEGTISRARKIYPLHELALWQPLHADSGFSKISKTFSFYKLETWLRSCLTGNPFGTSACLKSGKKLAWAHQVEGTTKRAKIACNTHVAPRMHRLVVMSQVYKQTLAKSSDTLAGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSIFVLGPVGTTLHLHSCDNVKVIAVCHRLSISSTTGCIFHVLTPTRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCRENSDTRVFQLLPPCEFYVFIIPFEMEGDTTEIPGGLPSVYQKALGQREQKIQIWQKTVKEAHLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVPPAAGSKQAAG", "length": 557 }, "evidence": [ { "id": "Q5ZKT1", "url": "https://omabrowser.org/oma/group/Q5ZKT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maintenance of Golgi location", "id": "GO:0051684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051684", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ], "pmid": "" }, { "name": "maintenance of centrosome location", "id": "GO:0051661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051661", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spindle pole centrosome", "id": "GO:0031616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031616", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKT1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 555, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKT1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKT1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT1" }, { "id": "PRU00659", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00659" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-CAP/cofactor C-like", "eco_id": "ECO_0000255", "start_pos": 302, "end_pos": 433, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 356, "end_pos": 358 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKT8-1", "uniprot_ac": "Q5ZKT8", "uniprot_id": "RM15_CHICK", "mass": { "chemical_mass": 33557.0, "monoisotopic_mass": 33557.0 }, "refseq": { "ac": "NP_001006388", "name": "large ribosomal subunit protein uL15m precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" }, "gene_names": [ { "name": "MRPL15", "type": "recommended", "evidence": [ { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8" } ] }, { "name": "MRPL15", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" } ] }, { "name": "RCJMB04_9c23", "type": "synonym", "evidence": [ { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL15m", "type": "recommended", "evidence": [ { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L15, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" }, { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8/entry#names_and_taxonomy" } ] }, { "name": "L15mt", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" }, { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8/entry#names_and_taxonomy" } ] }, { "name": "MRP-L15", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" }, { "id": "Q5ZKT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein uL15m precursor", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" } ] }, { "name": "large ribosomal subunit protein uL15m", "type": "synonym", "evidence": [ { "id": "NP_001006388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719996.1, CO635611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000043.1. On Sep 23, 2021 this sequence version replaced NP_001006388.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL15", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8", "locus": { "chromosome": "2", "start_pos": 110092529, "end_pos": 110082352, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004495", "url": "https://www.ensembl.org/id/ENSGALG00010004495" } ] } } ], "crossref": [ { "id": "Q5ZKT8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "421121", "url": "https://www.ncbi.nlm.nih.gov/gene/421121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421121", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKT8", "url": "https://www.orthodb.org/?gene=Q5ZKT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12934:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12934:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKT8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKT8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006388", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKT8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKT8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGNGVHGVHGALQLLRSLPKVSLANLRPNPGSKKPERRRGRGRYRGRKCGRGHKGERQRGNRPRLGFEGGQTPFYLSIPKYGFNEGHSCRRKYHPLSLQKLQYLIDLGRVDPTQPIDLTQLTNARGVTVQPLKRDYGVQLVEEGADIFAAKINIEVQRASELAIAAIEKNGGVVTASFYDPRSLEILIRPVPFFLRGQPIPKRMLPPEDLVRYYTDASNRGYLADPSKVAEARLELAKKYGYTLPDITKDELFKMLSTRKDPRQIFFGLAPGWIVNMADKKILKPTDERLLKYYSS", "length": 297, "header": "sp|Q5ZKT8-1|RM15_CHICK Isoform 1 of Large ribosomal subunit protein uL15m OS=Gallus gallus OX=9031 GN=MRPL15 PE=2 SV=1 CANONICAL=Q5ZKT8-1" }, "isoforms": [ { "isoform_ac": "Q5ZKT8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT8/entry#Q5ZKT8-1", "sequence": { "sequence": "MSGNGVHGVHGALQLLRSLPKVSLANLRPNPGSKKPERRRGRGRYRGRKCGRGHKGERQRGNRPRLGFEGGQTPFYLSIPKYGFNEGHSCRRKYHPLSLQKLQYLIDLGRVDPTQPIDLTQLTNARGVTVQPLKRDYGVQLVEEGADIFAAKINIEVQRASELAIAAIEKNGGVVTASFYDPRSLEILIRPVPFFLRGQPIPKRMLPPEDLVRYYTDASNRGYLADPSKVAEARLELAKKYGYTLPDITKDELFKMLSTRKDPRQIFFGLAPGWIVNMADKKILKPTDERLLKYYSS", "length": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKU4-1", "uniprot_ac": "Q5ZKU4", "uniprot_id": "INT2_CHICK", "mass": { "chemical_mass": 132884.0, "monoisotopic_mass": 132884.0 }, "refseq": { "ac": "NP_001025893", "name": "integrator complex subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893" }, "gene_names": [ { "name": "INTS2", "type": "recommended", "evidence": [ { "id": "Q5ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ] }, { "name": "INTS2", "type": "synonym", "evidence": [ { "id": "NP_001025893", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893" } ] }, { "name": "RCJMB04_9c3", "type": "synonym", "evidence": [ { "id": "Q5ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 2", "type": "recommended", "evidence": [ { "id": "Q5ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4/entry#names_and_taxonomy" } ] }, { "name": "Int2", "type": "synonym", "evidence": [ { "id": "Q5ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4/entry#names_and_taxonomy" } ] }, { "name": "int2", "type": "synonym", "evidence": [ { "id": "NP_001025893", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893" } ] }, { "name": "integrator complex subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001025893", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719990.1, SRR13267652.26293.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1. On Sep 23, 2021 this sequence version replaced NP_001025893.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025893", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893" } ] }, { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4#function" }, { "database": "UniProtKB", "id": "Q9H0H0", "url": "https://www.uniprot.org/uniprotkb/Q9H0H0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4", "locus": { "chromosome": "19", "start_pos": 7967372, "end_pos": 7952379, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029316", "url": "https://www.ensembl.org/id/ENSGALG00010029316" } ] } } ], "crossref": [ { "id": "Q5ZKU4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417640", "url": "https://www.ncbi.nlm.nih.gov/gene/417640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417640", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKU4", "url": "https://www.orthodb.org/?gene=Q5ZKU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKU4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKU4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025893", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025893", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKU4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDALLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRCDQRVHRSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV", "length": 1192, "header": "sp|Q5ZKU4-1|INT2_CHICK Isoform 1 of Integrator complex subunit 2 OS=Gallus gallus OX=9031 GN=INTS2 PE=2 SV=1 CANONICAL=Q5ZKU4-1" }, "isoforms": [ { "isoform_ac": "Q5ZKU4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4/entry#Q5ZKU4-1", "sequence": { "sequence": "MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDALLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRCDQRVHRSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV", "length": 1192, "header": "sp|Q5ZKU4-1|INT2_CHICK Isoform 1 of Integrator complex subunit 2 OS=Gallus gallus OX=9031 GN=INTS2 PE=2 SV=1 CANONICAL=Q5ZKU4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 414, "start_aa": "Thr", "end_pos": 414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417640", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU4", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], 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{ "name": "PAK1IP1", "type": "recommended", "evidence": [ { "id": "Q5ZKU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8" } ] }, { "name": "PAK1IP1", "type": "synonym", "evidence": [ { "id": "NP_001026170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026170" } ] }, { "name": "RCJMB04_9b18", "type": "synonym", "evidence": [ { "id": "Q5ZKU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8" } ] } ], "protein_names": [ { "name": "p21-activated protein kinase-interacting protein 1-like", "type": "recommended", "evidence": [ { "id": "Q5ZKU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8/entry#names_and_taxonomy" } ] }, { "name": "PAK1-interacting protein 1-like", "type": "synonym", "evidence": [ { "id": "Q5ZKU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8/entry#names_and_taxonomy" } ] }, { "name": "p21-activated protein kinase-interacting protein 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The reference sequence was derived from JAENSK010000040.1. On Oct 25, 2021 this sequence version replaced NP_001026170.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026170" } ] }, { "annotation": "Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. 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"database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKU8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKU8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELVAGCYEQILFGFAARPGEPWTVTPDFTHHAHTASLSAVAVNSKYVVTGSRDESIQIYDMRKKVEHGALLQHNGTITCLEFYGTAHLLSGAEDGLICIWNTKRWECLKSIKAHKGHVTSLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNLKQNAHIIKWSPDGEKYVTVITNKVDIYKLDTASITGTITIEKRISSIRFITDSVLAIAGDDEIIRFYSCDSQKCLCEFKARENRIKDIYSFEREGQHVIVTASSDGYIKVWNLDLNKINNVPSLLCEVSTKARLTCLAVWLDQASEMKENCGKAATSTEANESEKPSAVKKKKVCGMNKSGKLTKQRRRIVPAKRKLEAPLQKKKKKKQNSSE", "length": 369, "header": "sp|Q5ZKU8-1|PK1IP_CHICK Isoform 1 of p21-activated protein kinase-interacting protein 1-like OS=Gallus gallus OX=9031 GN=PAK1IP1 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"go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKU8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKU8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": 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"https://www.uniprot.org/uniprotkb/Q5ZKW2/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper and CTNNBIP1 domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001008450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008450" } ] }, { "name": "leucine zipper and ICAT homologous domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001008450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008450" } ] }, { "name": "protein LZIC", "type": "synonym", "evidence": [ { "id": "NP_001008450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008450" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719972.1, HAEK01004514.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Dec 16, 2004 this sequence version replaced XP_417604.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008450" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LZIC", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2", "locus": { "chromosome": "21", "start_pos": 3569352, "end_pos": 3591571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017112", "url": "https://www.ensembl.org/id/ENSGALG00010017112" } ] } } ], "crossref": [ { "id": "Q5ZKW2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002616", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002616", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419445", "url": "https://www.ncbi.nlm.nih.gov/gene/419445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKMMAGN", "url": "https://omabrowser.org/oma/group/TKMMAGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKW2", "url": "https://www.orthodb.org/?gene=Q5ZKW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47142:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47142:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKW2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKW2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKW2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRGTTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEINDSLKKIMSGDMTLVDELSGMQLAIQAAISQAFKTPEVIRMFAKKQPRQLRTRLAEMDRDLMVGKLGRDLYTQQKVEILTALRKLGEKLTQDDETFLSANAGAALSQFEKVSSDLGSGDKVFALASFEVEKAKQ", "length": 190, "header": "sp|Q5ZKW2-1|LZIC_CHICK Isoform 1 of Protein LZIC OS=Gallus gallus OX=9031 GN=LZIC PE=2 SV=1 CANONICAL=Q5ZKW2-1" }, "isoforms": [ { "isoform_ac": "Q5ZKW2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2/entry#Q5ZKW2-1", "sequence": { "sequence": "MASRGTTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEINDSLKKIMSGDMTLVDELSGMQLAIQAAISQAFKTPEVIRMFAKKQPRQLRTRLAEMDRDLMVGKLGRDLYTQQKVEILTALRKLGEKLTQDDETFLSANAGAALSQFEKVSSDLGSGDKVFALASFEVEKAKQ", "length": 190, "header": "sp|Q5ZKW2-1|LZIC_CHICK Isoform 1 of Protein LZIC OS=Gallus gallus OX=9031 GN=LZIC PE=2 SV=1 CANONICAL=Q5ZKW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419445", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A837-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLAANAGAILSQFEKVSTDLGSGDKVLALASFEVEKTKK", "length": 189 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LVC8-1", "protein_name": "Protein LZIC", "gene_name": "Lzic", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFHDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLREDDEAFLLANAGAALSQFEKVSTDLGSGDKVLALAGFEVEKAKK", "length": 190 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABI0P120-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLARDLYTQQKVEILTALRKLGEKLTADDENFLSANAGAILSQFEKVSTDLGLLPSCMNSPLLSLTPHQKY", "length": 191 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54ID4-1", "protein_name": "Protein LZIC", "gene_name": "lzic", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASRGKTETNKLKVNIEEQLNRLLAQLQDIEELKEDITQEEYDETKKDTLEQMKEFEQSLKKMMSGDMTLVSELGGVQLAIQAAVSQAFKTPEVIKLFAKKDQNSLRTKLGNIQRDVQLGKISKDAYIDQSVEILAALKKLDFVLSPEEEAFLEKHKSRSMSEFEKVSSNIGQGTKENILSSAASQIKNASK", "length": 192 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DHH7-1", "protein_name": "Protein LZIC", "gene_name": "lzic", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASRGKSETSKLRQNMEEQLDRLMQQLQDLEECREDLEEEEYEETKKETLEQLSEFNDSLKKLMSGNMTLVDELGGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDVMVGKLSRDVFTQQKVEILTALRKLGEKLTTEDEAFLAANASATLSHFEKVTASLGSEDKIMALASSGVGKTQT", "length": 190 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K3C3-1", "protein_name": "Protein LZIC", "gene_name": "Lzic", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERELYTQRKVEILTALRKLGEKLTEDDETFLSANASAVLSQFEKVSTELGSGDKVLALAGFDVEKAKK", "length": 190 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WZA0-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK", "length": 190 }, "evidence": [ { "id": "Q5ZKW2", "url": "https://omabrowser.org/oma/group/Q5ZKW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKW2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 190, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKW2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKW2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKW5-1", "uniprot_ac": "Q5ZKW5", "uniprot_id": "AR2BP_CHICK", "mass": { "chemical_mass": 17936.0, "monoisotopic_mass": 17936.0 }, "refseq": { "ac": "NP_001007971", "name": "ADP-ribosylation factor-like protein 2-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" }, "gene_names": [ { "name": "ARL2BP", "type": "recommended", "evidence": [ { "id": "Q5ZKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ] }, { "name": "ARL2BP", "type": "synonym", "evidence": [ { "id": "NP_001007971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" } ] }, { "name": "RCJMB04_8o4", "type": "synonym", "evidence": [ { "id": "Q5ZKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 2-binding protein", "type": "recommended", "evidence": [ { "id": "Q5ZKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like 2 binding protein", "type": "synonym", "evidence": [ { "id": "NP_001007971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" } ] }, { "name": "ADP-ribosylation factor-like protein 2-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001007971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" } ] }, { "name": "ARF-like 2-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001007971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" }, { "id": "Q5ZKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719969.1, AJ456558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ719969.1. On Dec 15, 2004 this sequence version replaced XP_424136.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971" } ] }, { "annotation": "Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL2BP", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5", "locus": { "chromosome": "11", "start_pos": 738491, "end_pos": 732229, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025800", "url": "https://www.ensembl.org/id/ENSGALG00010025800" } ] } } ], "crossref": [ { "id": "Q5ZKW5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000049492", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000049492", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426495", "url": "https://www.ncbi.nlm.nih.gov/gene/426495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426495", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426495", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CILEIIM", "url": "https://omabrowser.org/oma/group/CILEIIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZKW5", "url": "https://www.orthodb.org/?gene=Q5ZKW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15487:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15487:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11527", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11527", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKW5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKW5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKW5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METSEEENFGVAVSSPSDAEFDAVVGYLEDIIMDDDFQSIQRTFMEKHYQEFDDSEENKLIYTSIFNEYISLIEKYIEEKLLDRIPGFNMTAFTMSLQQHKDEMAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRSLDLSGGLVVTSLNKSSVSSS", "length": 156, "header": "sp|Q5ZKW5-1|AR2BP_CHICK Isoform 1 of ADP-ribosylation factor-like protein 2-binding protein OS=Gallus gallus OX=9031 GN=ARL2BP PE=2 SV=1 CANONICAL=Q5ZKW5-1" }, "isoforms": [ { "isoform_ac": "Q5ZKW5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5/entry#Q5ZKW5-1", "sequence": { "sequence": "METSEEENFGVAVSSPSDAEFDAVVGYLEDIIMDDDFQSIQRTFMEKHYQEFDDSEENKLIYTSIFNEYISLIEKYIEEKLLDRIPGFNMTAFTMSLQQHKDEMAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRSLDLSGGLVVTSLNKSSVSSS", "length": 156, "header": "sp|Q5ZKW5-1|AR2BP_CHICK Isoform 1 of ADP-ribosylation factor-like protein 2-binding protein OS=Gallus gallus OX=9031 GN=ARL2BP PE=2 SV=1 CANONICAL=Q5ZKW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426495", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426495", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SDE4-1", "protein_name": "ADP-ribosylation factor-like protein 2-binding protein", "gene_name": "ARL2BP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDALEEESFALSFSSASDAEFDAVVGYLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLIYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSTGLVVTSLCKSSSLPASQNNLRP", "length": 163 }, "evidence": [ { "id": "Q5ZKW5", "url": "https://omabrowser.org/oma/group/Q5ZKW5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32PC9-1", "protein_name": "ADP-ribosylation factor-like protein 2-binding protein", "gene_name": "ARL2BP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDALEEESFALSFSSASDAEFDAVVGYLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSVPASQNNLRP", "length": 163 }, "evidence": [ { "id": "Q5ZKW5", "url": "https://omabrowser.org/oma/group/Q5ZKW5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D385-1", "protein_name": "ADP-ribosylation factor-like protein 2-binding protein", "gene_name": "Arl2bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALEEESFALSFSSASDAEFDAVVGCLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSTPASQNNLRH", "length": 163 }, "evidence": [ { "id": "Q5ZKW5", "url": "https://omabrowser.org/oma/group/Q5ZKW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2Y0-1", "protein_name": "ADP-ribosylation factor-like protein 2-binding protein", "gene_name": "ARL2BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALEGESFALSFSSASDAEFDAVVGYLEDIIMDDEFQLLQRNFMDKYYLEFEDTEENKLIYTPIFNEYISLVEKYIEEQLLQRIPEFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSLPASQNNLRH", "length": 163 }, "evidence": [ { "id": "Q5ZKW5", "url": "https://omabrowser.org/oma/group/Q5ZKW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of tyrosine phosphorylation of STAT protein", "id": "GO:0042531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042531", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW5", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKW5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 156, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKW5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKW5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZKW8-1", "uniprot_ac": "Q5ZKW8", "uniprot_id": "HDX_CHICK", "mass": { "chemical_mass": 77251.0, "monoisotopic_mass": 77251.0 }, "refseq": { "ac": "NP_001026291", "name": "highly divergent homeobox", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026291" }, "gene_names": [ { "name": "HDX", "type": "recommended", "evidence": [ { "id": "Q5ZKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8" } ] }, { "name": "HDX", "type": "synonym", "evidence": [ { "id": "NP_001026291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026291" } ] }, { "name": "RCJMB04_8n18", "type": "synonym", "evidence": [ { "id": "Q5ZKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8" } ] } ], "protein_names": [ { "name": "Highly divergent homeobox", "type": "recommended", "evidence": [ { "id": "Q5ZKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8/entry#names_and_taxonomy" } ] }, { "name": "highly divergent homeobox", "type": "synonym", "evidence": [ { "id": "NP_001026291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026291" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719966.1, SRR13267659.279164.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ719966.1, JAENSK010000071.1, BU482030.1, BU320866.1, AJ735946.1, BU265998.1, BU351326.1 and BU304004.1. On Aug 8, 2005 this sequence version replaced XP_420256.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026291", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026291" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HDX", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8", "locus": { "chromosome": "4", "start_pos": 8924125, "end_pos": 8888635, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015449", "url": "https://www.ensembl.org/id/ENSGALG00010015449" } ] } } ], "crossref": [ { "id": "Q5ZKW8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZKW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007041", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422272", "url": "https://www.ncbi.nlm.nih.gov/gene/422272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422272", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZKW8", "url": "https://www.orthodb.org/?gene=Q5ZKW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11636:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11636:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:Q5ZKW8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKW8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026291", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKW8", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKW8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMSSKSALESGGAPPGTAHTAPSVPPEAMVRNVVNIARSQSQQSSWTSSNNDVIVTGIYSPASSSNRQGSTKQTNASMAEIHKTSIPRLPGKSDADFQQQHIPIGRQIPHCKNASLLVGEKTIILSRQTSVLNSANSIYSHTKKSYGGSSVQTAELVLPQKPMICHRPCKAELMGCQRLQKPEHAALASHGPPGQRANARDPCSTQNLEIREVFSLAVTDQPQRIVGGSTAQKHCSVEGSSLSIAMETGDVDDEYAREEELASMGAQIQSYSRYYESSSSIRVENQSAALSGPGRNVSCSSQMVNARDVPDSMLYHSRDYHLPARTSLHTSSTLYNSANTSRNTFSPHFTSSNQLRLSQNQNNYQISGNLTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVAAELNVDCEIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSDQSEFVSKSALNPGEETATEVGDDNDRNDEVSICLSEGSSQEETNEVLQNEEIHHKDDDRNPVSADNVKIEIIDDEESDMISNSEVDQMSSLLDYKNEEVRFIENELENHKQKYFELQTFTRSLILAIKSDDKEQQQALLSDLPPELEEMDFNHTSPEPDDTSFSLSSLSEKNASDSL", "length": 695, "header": "sp|Q5ZKW8-1|HDX_CHICK Isoform 1 of Highly divergent homeobox OS=Gallus gallus OX=9031 GN=HDX PE=2 SV=1 CANONICAL=Q5ZKW8-1" }, "isoforms": [ { 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"uniprot_ac": "Q5ZKW9", "uniprot_id": "MBNL1_CHICK", "mass": { "chemical_mass": 39670.0, "monoisotopic_mass": 39670.0 }, "refseq": { "ac": "NP_001026493", "name": "muscleblind-like protein 1 isoform 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" }, "gene_names": [ { "name": "MBNL1", "type": "recommended", "evidence": [ { "id": "Q5ZKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9" } ] }, { "name": "MBNL1", "type": "synonym", "evidence": [ { "id": "NP_001026493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ] }, { "name": "RCJMB04_8n15", "type": "synonym", "evidence": [ { "id": "Q5ZKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9" } ] } ], "protein_names": [ { "name": "Muscleblind-like protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9/entry#names_and_taxonomy" } ] }, { "name": "muscleblind-like 1", "type": "synonym", "evidence": [ { "id": "NP_001026493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ] }, { "name": "muscleblind-like protein 1 isoform 4", "type": "synonym", "evidence": [ { "id": "NP_001026493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ] }, { "name": "muscleblind-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001026493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719965.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Aug 8, 2005 this sequence version replaced XP_422835.1. Transcript Variant: This variant (4) lacks an in-frame segment and an alternate in-frame exon compared to variant 1. The encoded isoform (4) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ] }, { "annotation": "A novel role for MBNL1 during embryonic development, an alternative splicing regulator as a key player in endocardial cushion development.", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" }, { "database": "PubMed", "id": "19890912", "url": "https://glygen.org/publication/PubMed/19890912" } ] }, { "annotation": "Conserved developmental stage- and tissue-specific alternative splicing of MBNL transcripts is an important mechanism by which MBNL activity is regulated during embryonic development.", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" }, { "database": "PubMed", "id": "20009516", "url": "https://glygen.org/publication/PubMed/20009516" } ] }, { "annotation": "Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9#function" } ] }, { "annotation": "MBNL1 mRNAs were present throughout the retina, but the proteins was largely restricted to the periphery of the optic cup. MBNL1 immunoreactivity first appeared in their inner segments and became subsequently localized to their synaptic terminals.", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" }, { "database": "PubMed", "id": "18095352", "url": "https://glygen.org/publication/PubMed/18095352" } ] }, { "annotation": "MBNL1 negatively regulates cell invasion in the endocardial cushions by restricting the magnitude and timing of endocardial-derived TGFbeta3 production. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" }, { "database": "PubMed", "id": "22866814", "url": "https://glygen.org/publication/PubMed/22866814" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MBNL1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9", "locus": { "chromosome": "9", "start_pos": 23088263, "end_pos": 23135530, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001104", "url": "https://www.ensembl.org/id/ENSGALG00010001104" } ] } } ], "crossref": [ { "id": "Q5ZKW9", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12675:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12675:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKW9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKW9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKW9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKW9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAFNPYLGPVSPGLVPAEILPTAPMLVAGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSAMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 369, "header": "sp|Q5ZKW9-1|MBNL1_CHICK Isoform 1 of Muscleblind-like protein 1 OS=Gallus gallus OX=9031 GN=MBNL1 PE=2 SV=1 CANONICAL=Q5ZKW9-1" }, "isoforms": [ { "isoform_ac": "Q5ZKW9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9/entry#Q5ZKW9-1", "sequence": { "sequence": "MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAFNPYLGPVSPGLVPAEILPTAPMLVAGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSAMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM", "length": 369, "header": "sp|Q5ZKW9-1|MBNL1_CHICK Isoform 1 of Muscleblind-like protein 1 OS=Gallus gallus OX=9031 GN=MBNL1 PE=2 SV=1 CANONICAL=Q5ZKW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2008-01", "authors": "Huang Hu, Wahlin Karl J, McNally Minda, Irving Natasha D, Adler Ruben", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ], "reference": [ { "type": "PubMed", "id": "18095352", "url": "https://glygen.org/publication/PubMed/18095352" } ] }, { "title": "Muscleblind-like 1 is a negative regulator of TGF-beta-dependent epithelial-mesenchymal transition of atrioventricular canal endocardial cells.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2009-12", "authors": "Vajda Natalie A, Brimacombe Kyle R, LeMasters Kathryn E, Ladd Andrea N", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ], "reference": [ { "type": "PubMed", "id": "19890912", "url": "https://glygen.org/publication/PubMed/19890912" } ] }, { "title": "Conserved developmental alternative splicing of muscleblind-like (MBNL) transcripts regulates MBNL localization and activity.", "journal": "RNA biology", "date": "2010", "authors": "Terenzi Fulvia, Ladd Andrea N", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ], "reference": [ { "type": "PubMed", "id": "20009516", "url": "https://glygen.org/publication/PubMed/20009516" } ] }, { "title": "Loss of muscleblind-like 1 promotes invasive mesenchyme formation in endocardial cushions by stimulating autocrine TGF\u03b23.", "journal": "BMC developmental biology", "date": "2012-08-06", "authors": "LeMasters Kathryn E, Blech-Hermoni Yotam, Stillwagon Samantha J, Vajda Natalie A, Ladd Andrea N", "evidence": [ { "database": "RefSeq", "id": "NP_001026493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026493" } ], "reference": [ { "type": "PubMed", "id": "22866814", "url": "https://glygen.org/publication/PubMed/22866814" } ] } ], "pathway": [ { "id": "gga:425033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425033", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKW9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKW9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": 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introns SAMEA103992415, SAMEA103992692 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000356.1. On Jan 13, 2005 this sequence version replaced XP_418046.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006327" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. 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"categories": [ "Protein Classification" ] }, { "id": "PTHR12465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12465:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12465:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZKY9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZKY9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZKY9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZKY9-1", "url": 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195 }, "evidence": [ { "id": "Q5ZKY9", "url": "https://omabrowser.org/oma/group/Q5ZKY9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XIE9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 20", "gene_name": "Med20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVTCVSQMPVAEGKSVQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPTVFGNRHDAVYGPADTMVQYMELFNKVRKQQQVPVAGIR", "length": 212 }, "evidence": [ { "id": "Q5ZKY9", "url": "https://omabrowser.org/oma/group/Q5ZKY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DBX1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 20", "gene_name": "med20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719935.1, SRR13267649.2919.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000006.1. On Sep 23, 2021 this sequence version replaced NP_001026743.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026743" } ] }, { "annotation": "Involved in the maturation of specific proteins in the endoplasmic reticulum. May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKZ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZKZ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMF2", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9", "locus": { "chromosome": "1", "start_pos": 1188298, "end_pos": 1195071, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006421", "url": "https://www.ensembl.org/id/ENSGALG00010006421" } ] } } ], "crossref": [ { "id": "Q5ZKZ9", "url": 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"categories": [ "Protein" ] }, { "id": "Q5ZKZ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEPPRRPRELFLAGLAAAYLAAFVSLYLQIPGLYGRDGILPARRVLRLSGKGLWEQLRDVPTLLWLGPQLGLDTEQGMELLCLLGAVASMGALLCAPLRDCLLFAVLRVFYLSLYQVGQVFLYFQWDSLLLEAGFLAVLVAPLRLFKWRSTAWRPHDSVTFWLVRWLLFRLMFASGVVKLTSRCPTWWGLTALTYHYETQCIPTPAAWYAHQLPVWFQKFSVVATYVIEIAVPLLFFMPIRRLRLFAFYCQVLLQILIILTGNYNFFNALTIVLAFSLLDEEHMGRWMGRGKRKHGSSAWPPTLLSFLSTLLELATYALLLYWSVHYFSLEIDWEKGLLESKVAFTYHEFTQWLRAVTLPLVGLGFLSLSWEILSALYRCACVRGFFWKLWATLQWAVFATATVGMFAISLVPFTYIDYESNGKLWPGIHQMFSAVERFQVVNSYGLFRRMTGVGGRPEVVLEGSYDKQSWTEIEFMYKPGNVSAAPAVVAPHQPRLDWQMWFAALAHHSSSPWFASFVHRLLQGKEDVIRLVQVDEDKYPFSTQPPVYLRAQLYKYWFTHSAESGAGAAQWWRRQHVQEFFPTVSVGDPTLDGLLAQHGLKDKLPLKRPVDAFLPWLLSSVRQLSRPFSPHVVLWSLYVVAATTCLLRAMARRPRGGAPPTRHKAPKQPRGDQGEKNGQLRRKEGREAEERGEGRSRGAADGEGPRGTKRRK", "length": 714, "header": "sp|Q5ZKZ9-1|LMF2_CHICK Isoform 1 of Lipase maturation factor 2 OS=Gallus gallus OX=9031 GN=LMF2 PE=2 SV=2 CANONICAL=Q5ZKZ9-1" }, "isoforms": [ { "isoform_ac": "Q5ZKZ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9/entry#Q5ZKZ9-1", "sequence": { "sequence": "MGEPPRRPRELFLAGLAAAYLAAFVSLYLQIPGLYGRDGILPARRVLRLSGKGLWEQLRDVPTLLWLGPQLGLDTEQGMELLCLLGAVASMGALLCAPLRDCLLFAVLRVFYLSLYQVGQVFLYFQWDSLLLEAGFLAVLVAPLRLFKWRSTAWRPHDSVTFWLVRWLLFRLMFASGVVKLTSRCPTWWGLTALTYHYETQCIPTPAAWYAHQLPVWFQKFSVVATYVIEIAVPLLFFMPIRRLRLFAFYCQVLLQILIILTGNYNFFNALTIVLAFSLLDEEHMGRWMGRGKRKHGSSAWPPTLLSFLSTLLELATYALLLYWSVHYFSLEIDWEKGLLESKVAFTYHEFTQWLRAVTLPLVGLGFLSLSWEILSALYRCACVRGFFWKLWATLQWAVFATATVGMFAISLVPFTYIDYESNGKLWPGIHQMFSAVERFQVVNSYGLFRRMTGVGGRPEVVLEGSYDKQSWTEIEFMYKPGNVSAAPAVVAPHQPRLDWQMWFAALAHHSSSPWFASFVHRLLQGKEDVIRLVQVDEDKYPFSTQPPVYLRAQLYKYWFTHSAESGAGAAQWWRRQHVQEFFPTVSVGDPTLDGLLAQHGLKDKLPLKRPVDAFLPWLLSSVRQLSRPFSPHVVLWSLYVVAATTCLLRAMARRPRGGAPPTRHKAPKQPRGDQGEKNGQLRRKEGREAEERGEGRSRGAADGEGPRGTKRRK", "length": 714, "header": "sp|Q5ZKZ9-1|LMF2_CHICK Isoform 1 of Lipase maturation factor 2 OS=Gallus gallus OX=9031 GN=LMF2 PE=2 SV=2 CANONICAL=Q5ZKZ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 483, "start_aa": "Asn", "end_pos": 483, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn483", "evidence": [ { "id": "Q5ZKZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter 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"https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q5ZKZ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZKZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZKZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 714, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZKZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZKZ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 483 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZL12-1", "uniprot_ac": "Q5ZL12", "uniprot_id": "PPR21_CHICK", "mass": { "chemical_mass": 88858.0, "monoisotopic_mass": 88858.0 }, "refseq": { "ac": "NP_001012891", "name": "protein phosphatase 1 regulatory subunit 21", "summary": 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"NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "name": "RCJMB04_8e10", "type": "synonym", "evidence": [ { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 21", "type": "recommended", "evidence": [ { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 128", "type": "synonym", "evidence": [ { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#names_and_taxonomy" } ] }, { "name": "Ferry endosomal RAB5 effector complex subunit 2", "type": "synonym", "evidence": [ { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#names_and_taxonomy" } ] }, { "name": "Fy-2", "type": "synonym", "evidence": [ { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#names_and_taxonomy" } ] }, { "name": "KLRAQ motif containing 1", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "name": "KLRAQ motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" }, { "id": "Q5ZL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain containing 128", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "name": "coiled-coil domain-containing protein 128", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "name": "ferry endosomal RAB5 effector complex subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "name": "protein phosphatase 1 regulatory subunit 21", "type": "synonym", "evidence": [ { "id": "NP_001012891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719922.1, SRR13267655.85671.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000061.1. On Sep 23, 2021 this sequence version replaced NP_001012891.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012891", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891" } ] }, { "annotation": "Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (By similarity). Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12#function" }, { "database": "UniProtKB", "id": "Q6ZMI0", "url": "https://www.uniprot.org/uniprotkb/Q6ZMI0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R21", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12", "locus": { "chromosome": "3", "start_pos": 9167481, "end_pos": 9137489, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017797", "url": "https://www.ensembl.org/id/ENSGALG00010017797" } ] } } ], "crossref": [ { "id": "Q5ZL12", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL12", "database": "AlphaFoldDB", "categories": [] }, { "id": "421287", "url": "https://www.ncbi.nlm.nih.gov/gene/421287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421287", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZL12", "url": "https://www.orthodb.org/?gene=Q5ZL12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21448:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21448:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL12", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL12", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012891", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL12-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSASLKEQLKMKDQSLRKLQQEMDSLTFRNQQLAKRVELLQDELSLSETRGKKNKKSAESSSQLSQEQKSVFNEDLQKKIEENERLHILYFEADEQHKRLEAELRTKLEVLESDAAQHQAVVDSLTRKYTDTIEKLQNDKSKLEIKSQTLEREAKDCRLRTEECQQQLKNLQAALGSRLEESLCIINEKVPFNDTRSNRYNALNVPLHNRRYQLKLRDLAGQALSFVQEIVTALLNFHTYTEQKAQIFPIDSATDTISPLNQKFSQYLHENAFYVRPLEEGMLQLFESITEDTVTVLETAVKLKAFSEHLASYLCFLRKILPYQLKSLEEECESSLCTAALKARNMELHRDMKRLTAIFEKLHTYVSLLALPSTKPEGLLRTNYSLVFTNIAASLHGSHDILKDISKHYSQKATLEQDVPTATQKLVTTNDCILSSILSLTNGVGKIASFFSNNLDHFTSSLSYGPKGGTEFISPLSAECMLQYKKKAVAYMKSLKKPCADSVPYEEALANRRVLLSSTESREGLAQQVQQSLEKIAKLEQEKEHWMLEAQLAKIKLEKENQKLKNSLSGHLAETVQERSVLSNTAEQKEETTEKSQREPIKTTSLIGMLTITTDNEKVPDVESREDLIKKHYMARIAELTSHLQLADSKSVHFHAECRALAKRLSLAEKSKESLTEELKLASQSISRLQDELMTTKRSYEDQLSMMSDHLCSMNETLTKQREEIDTLKMTSKGNSKKNKTR", "length": 779, "header": "sp|Q5ZL12-1|PPR21_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 21 OS=Gallus gallus OX=9031 GN=PPP1R21 PE=2 SV=1 CANONICAL=Q5ZL12-1" }, "isoforms": [ { "isoform_ac": "Q5ZL12-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12/entry#Q5ZL12-1", "sequence": { "sequence": "MAATAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSASLKEQLKMKDQSLRKLQQEMDSLTFRNQQLAKRVELLQDELSLSETRGKKNKKSAESSSQLSQEQKSVFNEDLQKKIEENERLHILYFEADEQHKRLEAELRTKLEVLESDAAQHQAVVDSLTRKYTDTIEKLQNDKSKLEIKSQTLEREAKDCRLRTEECQQQLKNLQAALGSRLEESLCIINEKVPFNDTRSNRYNALNVPLHNRRYQLKLRDLAGQALSFVQEIVTALLNFHTYTEQKAQIFPIDSATDTISPLNQKFSQYLHENAFYVRPLEEGMLQLFESITEDTVTVLETAVKLKAFSEHLASYLCFLRKILPYQLKSLEEECESSLCTAALKARNMELHRDMKRLTAIFEKLHTYVSLLALPSTKPEGLLRTNYSLVFTNIAASLHGSHDILKDISKHYSQKATLEQDVPTATQKLVTTNDCILSSILSLTNGVGKIASFFSNNLDHFTSSLSYGPKGGTEFISPLSAECMLQYKKKAVAYMKSLKKPCADSVPYEEALANRRVLLSSTESREGLAQQVQQSLEKIAKLEQEKEHWMLEAQLAKIKLEKENQKLKNSLSGHLAETVQERSVLSNTAEQKEETTEKSQREPIKTTSLIGMLTITTDNEKVPDVESREDLIKKHYMARIAELTSHLQLADSKSVHFHAECRALAKRLSLAEKSKESLTEELKLASQSISRLQDELMTTKRSYEDQLSMMSDHLCSMNETLTKQREEIDTLKMTSKGNSKKNKTR", "length": 779, "header": "sp|Q5ZL12-1|PPR21_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 21 OS=Gallus gallus OX=9031 GN=PPP1R21 PE=2 SV=1 CANONICAL=Q5ZL12-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421287", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421287", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL12", "url": "https://www.uniprot.org/uniprotkb/Q5ZL12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZL12-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 779, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZL12-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZL12" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 776, "end_pos": 778 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZL26-1", "uniprot_ac": "Q5ZL26", "uniprot_id": "KPRB_CHICK", "mass": { "chemical_mass": 40804.0, "monoisotopic_mass": 40804.0 }, "refseq": {}, "gene_names": [ { "name": "PRPSAP2", "type": "recommended", "evidence": [ { "id": "Q5ZL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ] }, { "name": "RCJMB04_8b17", "type": "synonym", "evidence": [ { "id": "Q5ZL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ] } ], "protein_names": [ { "name": "Phosphoribosyl pyrophosphate synthase-associated protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26/entry#names_and_taxonomy" } ] }, { "name": "PRPP synthase-associated protein 2", "type": "synonym", "evidence": [ { "id": "Q5ZL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRPSAP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26", "locus": { "chromosome": "14", "start_pos": 5140918, "end_pos": 5126300, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017775", "url": "https://www.ensembl.org/id/ENSGALG00010017775" } ] } } ], "crossref": [ { "id": "Q5ZL26", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL26", "database": "AlphaFoldDB", "categories": [] }, { "id": "416521", "url": "https://www.ncbi.nlm.nih.gov/gene/416521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416521", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416521", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZL26", "url": "https://www.orthodb.org/?gene=Q5ZL26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL26", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL26", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL26-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCVPSTETGAIMNITKGGLVLFSANSNSSCMELSKRIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDMVDGRHSPPTAKNVAAIHRSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD", "length": 369, "header": "sp|Q5ZL26-1|KPRB_CHICK Isoform 1 of Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Gallus gallus OX=9031 GN=PRPSAP2 PE=2 SV=1 CANONICAL=Q5ZL26-1" }, "isoforms": [ { "isoform_ac": "Q5ZL26-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26/entry#Q5ZL26-1", "sequence": { "sequence": "MFCVPSTETGAIMNITKGGLVLFSANSNSSCMELSKRIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDMVDGRHSPPTAKNVAAIHRSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD", "length": 369, "header": "sp|Q5ZL26-1|KPRB_CHICK Isoform 1 of Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Gallus gallus OX=9031 GN=PRPSAP2 PE=2 SV=1 CANONICAL=Q5ZL26-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, 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"https://www.uniprot.org/uniprotkb/Q5ZL26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL26", "url": "https://www.uniprot.org/uniprotkb/Q5ZL26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZL26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 369, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZL26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZL26" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZL42-1", "uniprot_ac": "Q5ZL42", "uniprot_id": "5MP1_CHICK", "mass": { "chemical_mass": 47842.0, "monoisotopic_mass": 47842.0 }, "refseq": { "ac": "NP_001006358", "name": "eIF5-mimic protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" }, "gene_names": [ { "name": "BZW2", "type": "recommended", "evidence": [ { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ] }, { "name": "5MP1", "type": "synonym", "evidence": [ { "id": "NP_001006358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" }, { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ] }, { "name": "BZW2", "type": "synonym", "evidence": [ { "id": "NP_001006358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" } ] }, { "name": "RCJMB04_7o12", "type": "synonym", "evidence": [ { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ] } ], "protein_names": [ { "name": "eIF5-mimic protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42/entry#names_and_taxonomy" } ] }, { "name": "Basic leucine zipper and W2 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42/entry#names_and_taxonomy" } ] }, { "name": "basic leucine zipper and W2 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" } ] }, { "name": "eIF5-mimic protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01051514.1, HAEL01000055.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000036.1. On Mar 7, 2015 this sequence version replaced NP_001006358.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358" } ] }, { "annotation": "Translation initiation regulator which may repress non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42#function" }, { "database": "UniProtKB", "id": "Q9Y6E2", "url": "https://www.uniprot.org/uniprotkb/Q9Y6E2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BZW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42", "locus": { "chromosome": "2", "start_pos": 28434774, "end_pos": 28382647, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005255", "url": "https://www.ensembl.org/id/ENSGALG00010005255" } ] } } ], "crossref": [ { "id": "Q5ZL42", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420594", "url": "https://www.ncbi.nlm.nih.gov/gene/420594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420594", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZL42", "url": "https://www.orthodb.org/?gene=Q5ZL42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL42", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL42", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL42-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEEFRI", "length": 414, "header": "sp|Q5ZL42-1|5MP1_CHICK Isoform 1 of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=2 SV=1 CANONICAL=Q5ZL42-1" }, "isoforms": [ { "isoform_ac": "Q5ZL42-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42/entry#Q5ZL42-1", "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEEFRI", "length": 414, "header": "sp|Q5ZL42-1|5MP1_CHICK Isoform 1 of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=2 SV=1 CANONICAL=Q5ZL42-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:420594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420594", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL42", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZL42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 414, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZL42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZL42" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL42" }, { "id": "PRU00695", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00695" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000255", "start_pos": 248, "end_pos": 414, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZL77-1", "uniprot_ac": "Q5ZL77", "uniprot_id": "RIC8A_CHICK", "mass": { "chemical_mass": 61504.0, "monoisotopic_mass": 61504.0 }, "refseq": { "ac": "NP_001026345", "name": "chaperone Ric-8A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" }, "gene_names": [ { "name": "RIC8A", "type": "recommended", "evidence": [ { "id": "Q5ZL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ] }, { "name": "RCJMB04_7f5", "type": "synonym", "evidence": [ { "id": "Q5ZL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ] }, { "name": "RIC8A", "type": "synonym", "evidence": [ { "id": "NP_001026345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] } ], "protein_names": [ { "name": "Chaperone Ric-8A", "type": "recommended", "evidence": [ { "id": "Q5ZL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77/entry#names_and_taxonomy" } ] }, { "name": "Protein Ric-8A", "type": "synonym", "evidence": [ { "id": "NP_001026345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] }, { "name": "Synembryn-A", "type": "synonym", "evidence": [ { "id": "Q5ZL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77/entry#names_and_taxonomy" } ] }, { "name": "chaperone Ric-8A", "type": "synonym", "evidence": [ { "id": "NP_001026345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] }, { "name": "resistance to inhibitors of cholinesterase 8 homolog A", "type": "synonym", "evidence": [ { "id": "NP_001026345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] }, { "name": "synembryn-A", "type": "synonym", "evidence": [ { "id": "NP_001026345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719857.1, SRR13267656.10776.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000212.1. On Aug 8, 2005 this sequence version replaced XP_420919.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345" } ] }, { "annotation": "Chaperone that specifically binds and folds nascent G alpha proteins prior to G protein heterotrimer formation, promoting their stability and activity: folds GNAI1, GNAO1, GNA13 and GNAQ. Does not fold G(s) G-alpha proteins GNAS nor GNAL. Also acts as a guanine nucleotide exchange factor (GEF) for G alpha proteins by stimulating exchange of bound GDP for free GTP.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77#function" }, { "database": "UniProtKB", "id": "Q80ZG1", "url": "https://www.uniprot.org/uniprotkb/Q80ZG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIC8A", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77", "locus": { "chromosome": "5", "start_pos": 1812845, "end_pos": 1823944, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020925", "url": "https://www.ensembl.org/id/ENSGALG00010020925" } ] } } ], "crossref": [ { "id": "Q5ZL77", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004191", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422987", "url": "https://www.ncbi.nlm.nih.gov/gene/422987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422987", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NADPIFT", "url": "https://omabrowser.org/oma/group/NADPIFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZL77", "url": "https://www.orthodb.org/?gene=Q5ZL77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL77", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL77", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL77-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELRTVVATVESGEQDAVLKVLQIYNQEKSQCFTFDDEEREERKKMAQLLIKFLERELQPSCQVTCLESIRILSRDKYCLEPFTTEEGLKTLSRHAGIDYSEELIREVPDLEVILESLKCLCNIVFSSPRAQELTAEARLVVGLTKRIKLYNERSLPHEVKFFDLRLLFLLTALRVDIRQQLAQELRGISLMTDTLELTLGVKWMDPYEVATEEGLLPPLPRQETERAMEILKVLFNITFDSSKREVDEEDAALYRHLGALLRHCLMISADGEDRTEEFHSHTVNLLGNLPLKCLDVLLTPKVRPGSLEYMGVNMDAVNILLDFLERRLDRGHKLKESLTPVLNLLTESARVHRQTRKFLKAKVLPPLRDVKNRPEVGNSLRNKLVRLMTHIDTDVKHCAAEFLFVLCKESVSRFVKYTGYGNAAGLLAARGLMAGGREEGEYSEDEDTDTEEYKEAKPNINPVTGRVEEKLPNPMEGMTEEQKEYEAMKLVNMFDKLSREQVIQPMGITPSGNLAPMENAIRDMADERSSSDSDLGLD", "length": 539, "header": "sp|Q5ZL77-1|RIC8A_CHICK Isoform 1 of Chaperone Ric-8A OS=Gallus gallus OX=9031 GN=RIC8A PE=2 SV=1 CANONICAL=Q5ZL77-1" }, "isoforms": [ { "isoform_ac": "Q5ZL77-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77/entry#Q5ZL77-1", "sequence": { "sequence": "MELRTVVATVESGEQDAVLKVLQIYNQEKSQCFTFDDEEREERKKMAQLLIKFLERELQPSCQVTCLESIRILSRDKYCLEPFTTEEGLKTLSRHAGIDYSEELIREVPDLEVILESLKCLCNIVFSSPRAQELTAEARLVVGLTKRIKLYNERSLPHEVKFFDLRLLFLLTALRVDIRQQLAQELRGISLMTDTLELTLGVKWMDPYEVATEEGLLPPLPRQETERAMEILKVLFNITFDSSKREVDEEDAALYRHLGALLRHCLMISADGEDRTEEFHSHTVNLLGNLPLKCLDVLLTPKVRPGSLEYMGVNMDAVNILLDFLERRLDRGHKLKESLTPVLNLLTESARVHRQTRKFLKAKVLPPLRDVKNRPEVGNSLRNKLVRLMTHIDTDVKHCAAEFLFVLCKESVSRFVKYTGYGNAAGLLAARGLMAGGREEGEYSEDEDTDTEEYKEAKPNINPVTGRVEEKLPNPMEGMTEEQKEYEAMKLVNMFDKLSREQVIQPMGITPSGNLAPMENAIRDMADERSSSDSDLGLD", "length": 539, "header": "sp|Q5ZL77-1|RIC8A_CHICK Isoform 1 of Chaperone Ric-8A OS=Gallus gallus OX=9031 GN=RIC8A PE=2 SV=1 CANONICAL=Q5ZL77-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422987", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A098KXF9-1", "protein_name": "Synembryn", "gene_name": "Ric8a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPRAVADALETGEEDTVTEALQSFNREHSQSFTFDDAQQEDRKRLAKLLVSLLEQGLSPSHRVTWLQTIRILTRDRSCLDSFASRQSLHALACYADITISEEPIPQPPDMDVLLESLKCLCNLVLSSPAAQMLAAEARLVVRLVERVGLYRKRSYPHEVQFFDLRLLFLLTALRTDVRQQLFQELHGVRLLTEALELTLGVGPKEKPPVVLPAQETERAMEILKVLFNITFDSVKREVDEEDAALYRYLGTLLRHCVMVAAAGDRTEEFHGHTVNLLGNLPLKCLDVLLALELHEGSLEFMGVNMEVISALLAFLEKRLHQTHRLKECVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGDLLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTEEYREAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGHLTSLQDAMCETMEGQLSSDPDSDPD", "length": 530 }, "evidence": [ { "id": "Q5ZL77", "url": "https://omabrowser.org/oma/group/Q5ZL77/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TIR3-1", "protein_name": "Chaperone Ric-8A", "gene_name": "Ric8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPRAVADALETGEEDAVTEALRSFNREHSQSFTFDDAQQEDRKRLAKLLVSVLEQGLSPKHRVTWLQTIRILSRDRSCLDSFASRQSLHALACYADITVSEEPIPQSPDMDVLLESLKCLCNLVLSSPTAQMLAAEARLVVRLAERVGLYRKRSYPHEVQFFDLRLLFLLTALRTDVRQQLFQELHGVRLLTDALELTLGVAPKENPPVMLPAQETERAMEILKVLFNITFDSVKREVDEEDAALYRYLGTLLRHCVMVEAAGDRTEEFHGHTVNLLGNLPLKCLDVLLALELHEGSLEFMGVNMDVISALLAFLEKRLHQTHRLKECVAPVLNVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGDLLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTEEYREAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGHLTSLQDAMCETMEGQLSSDPDSDPD", "length": 530 }, "evidence": [ { "id": "Q5ZL77", "url": "https://omabrowser.org/oma/group/Q5ZL77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5E9J8-1", "protein_name": "Chaperone Ric-8A", "gene_name": "RIC8A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPRAVADALETGEEDVVMEALRAYNRENSQSFTFDDAQQEDRKRLAKLLVSVLEQGLPPSRRVIWLQSIRILSRDRSCLDSFTSRRSLQALACYAGISASQGSVPEPLNMDVVLESLKCLCNLVLSSPVAQALAAEAGLVVRLAERVGLCRQSSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELQGVRLLTRALELTLGMTEGERHPELLPPQETERAMEILKVLFNITFDSIKREVDEEDAALYRHLGTLLRHCVMLAAAGDRTEELHGHAVNLLGNLPVKCLDVLLTLEPHEGSLEFLGVNMDVIRVLLSFMEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGELLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGQLTSLQDAMCETMEGQLSSDPDSDPD", "length": 530 }, "evidence": [ { "id": "Q5ZL77", "url": "https://omabrowser.org/oma/group/Q5ZL77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NPQ8-1", "protein_name": "Chaperone Ric-8A", "gene_name": "RIC8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLPPSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELKGVRLLTDTLELTLGVTPEGNPPPTLLPSQETERAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVNLLGNLPLKCLDVLLTLEPHGDSTEFMGVNMDVIRALLIFLEKRLHKTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLSSDPDSDPD", "length": 531 }, "evidence": [ { "id": "Q5ZL77", "url": "https://omabrowser.org/oma/group/Q5ZL77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W358-1", "protein_name": "Chaperone Ric-8", "gene_name": "ric8a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METEHLKRLEAKEADHIPAILDEFNTKNADLLVFDSFRTDNLWHELWLAIFGILDDQRLSHLHTQCLNTVRILTRDEFSLQTNYIEQEVNTLLKLARIEAGSLKLPATPDELKQEEREEPQLEPSQAQSEVIAEALKCLCNLVYQSSDCRRQCLRQHCLDAILKRVASSMRHPCALEYYDMKLLFLLTALEPAARSRLQIDLNGLTYMTKWLDDKLGEDSVGEEQLNIICELLKVMFNVTSAPDKSPNEYEIQSLHLTGVLRELLLRFGDLATEKDRAVVTHAINLLTNISGSCLTELTLRCSNAELESHKEREQDNEKEKDTEAGAGAKPRECCSQCFEKRNVRSLDVLLRYLRQSLAQQEAEASSHELLSPVLTVLVKCARSDRVMRHYLRQEILPPLRDVSQRPEVGQELRNHLCRFLTLPAMILRDLSAELLFVLCKENVGRMIKYTGYGNAAGLFAKRGILDCRRVEGTDYSSDSEDSDTEEYKQQQQGINPVLGCVEPRSKSHLDDISEEQKEYEAMQLVNLIEQLRQGGIVKPAMIDKDGRPQPLEHILQLQEELPQQQLDQKRKT", "length": 573 }, "evidence": [ { "id": "Q5ZL77", "url": "https://omabrowser.org/oma/group/Q5ZL77/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL77", "url": "https://www.uniprot.org/uniprotkb/Q5ZL77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZL77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 539, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZL77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZL77" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZL91-1", "uniprot_ac": "Q5ZL91", "uniprot_id": "INT7_CHICK", "mass": { "chemical_mass": 106531.0, "monoisotopic_mass": 106531.0 }, "refseq": {}, "gene_names": [ { "name": "INTS7", "type": "recommended", "evidence": [ { "id": "Q5ZL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ] }, { "name": "RCJMB04_7c6", "type": "synonym", "evidence": [ { "id": "Q5ZL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 7", "type": "recommended", "evidence": [ { "id": "Q5ZL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91/entry#names_and_taxonomy" } ] }, { "name": "Int7", "type": "synonym", "evidence": [ { "id": "Q5ZL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91#function" }, { "database": "UniProtKB", "id": "Q9NVH2", "url": "https://www.uniprot.org/uniprotkb/Q9NVH2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS7", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91", "locus": { "chromosome": "3", "start_pos": 21771201, "end_pos": 21738435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020590", "url": "https://www.ensembl.org/id/ENSGALG00010020590" } ] } } ], "crossref": [ { "id": "Q5ZL91", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZL91", "database": "AlphaFoldDB", "categories": [] }, { "id": "421374", "url": "https://www.ncbi.nlm.nih.gov/gene/421374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421374", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZL91", "url": "https://www.orthodb.org/?gene=Q5ZL91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13322:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13322:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZL91", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZL91", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZL91-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSMASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAANFSAQSKDFAAGICNKISEMIQGLATPVDLKLKLIPILQHMHHDASLASSSRQLLQQLVTSYPSTKMVIVTLHTFTLLAASSLVDIPKQVQLLLQYLKNDPRKAVKRLAIQDLKLLANKIPHTWSRENIQALCESALHTPYDSLKLGMLSVLSTLSGTIAIKQYFSSAPGTAATTARSFDLVKLAQECCYHNNRGIAAHGVRILTNISASCQEKDLLPLEQDAVFGLESLLVLCSQDDSPGAQATLKITLTCMVKLVKCRPHLSQSVVESLLTQLHSAQDAARILMCHCLAAIAMQLPVLADGMLGDLMELYKVIGRSTTDKKQELLVSLATVIFVSSQKALSPEIKTVIKQQLENASNGWTAYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEDNYSSALSCIAEALKSYHKGIASLTAASTPLNPLSFQCGFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTSGNDLQRCGRISNQMKLSMEEFRNLAVRYGDLYQSSFDADSATLRNVELQQQSCLLISHAIEALILDPESANFQEYSSNGAAHVESEYERRMMSVFNHVLEEVESLNRKYAPVSYLHTACLCSAVIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSVLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFVILDTHNITVESSVIDSNGIVWKTGPKTTIFVKSLEDPYSQQVRLQQQQGQPPSQQQQQRTAYSRF", "length": 961, "header": "sp|Q5ZL91-1|INT7_CHICK Isoform 1 of Integrator complex subunit 7 OS=Gallus gallus OX=9031 GN=INTS7 PE=2 SV=1 CANONICAL=Q5ZL91-1" }, "isoforms": [ { "isoform_ac": "Q5ZL91-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91/entry#Q5ZL91-1", "sequence": { "sequence": "MAAGGKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSMASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAANFSAQSKDFAAGICNKISEMIQGLATPVDLKLKLIPILQHMHHDASLASSSRQLLQQLVTSYPSTKMVIVTLHTFTLLAASSLVDIPKQVQLLLQYLKNDPRKAVKRLAIQDLKLLANKIPHTWSRENIQALCESALHTPYDSLKLGMLSVLSTLSGTIAIKQYFSSAPGTAATTARSFDLVKLAQECCYHNNRGIAAHGVRILTNISASCQEKDLLPLEQDAVFGLESLLVLCSQDDSPGAQATLKITLTCMVKLVKCRPHLSQSVVESLLTQLHSAQDAARILMCHCLAAIAMQLPVLADGMLGDLMELYKVIGRSTTDKKQELLVSLATVIFVSSQKALSPEIKTVIKQQLENASNGWTAYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEDNYSSALSCIAEALKSYHKGIASLTAASTPLNPLSFQCGFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTSGNDLQRCGRISNQMKLSMEEFRNLAVRYGDLYQSSFDADSATLRNVELQQQSCLLISHAIEALILDPESANFQEYSSNGAAHVESEYERRMMSVFNHVLEEVESLNRKYAPVSYLHTACLCSAVIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSVLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFVILDTHNITVESSVIDSNGIVWKTGPKTTIFVKSLEDPYSQQVRLQQQQGQPPSQQQQQRTAYSRF", "length": 961, "header": "sp|Q5ZL91-1|INT7_CHICK Isoform 1 of Integrator complex subunit 7 OS=Gallus gallus OX=9031 GN=INTS7 PE=2 SV=1 CANONICAL=Q5ZL91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421374", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q5ZL91", "url": "https://www.uniprot.org/uniprotkb/Q5ZL91" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": 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"MGILSITDQPPLVQAIFNRDVEEVRSLLNQKENINVLDQERRTPLHTAAYIGDVAILELLILSGANVNAKDTVWLTPLHRAAASRNEKALHLLLKHSADVNARDKYWQTPLHVAAANRATKCVEAIIPLLSTVNVADRTGRTALHHAVHSGHLEMVNLLLNKGASLSTCDKKDRQPIHWAAFLGHLEVLKLLVARGADVMCKDKKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSFGNTALHIACYMGQDAVANELVNYGANVNQPNEKGFTPLHFAAVSTNGALCLELLVNNGADVNFQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCTVTLVTAGASINEADCKGCTPLHYAAASDTYRRAETHSGNSHDTDEEPLKESRMKEAFFCLEFLLDNGADPSLRDKQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALYLATERGSTECVEVLTSHGASALVKERKRKWTPLHAAAANGNTDSLHLLIDSGERADITDVMDIHGQTPLMLAIMNGHVDCVHLLLEKGSTADAADKRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRTLLQAALSTDPLDSVVDYSGYSPMHWASYSGHEDCLELLLEHNPFAYLEGNPFTPLHCAVINNQDSTAEMLVEALGAKIVNSRDAKGRTPLHAAAFADNIHGLQLLLRHQAEVDTTDKLGRTPLMMASENGHTAAVEFLLYQAKANITVLDVNKNTALHLACSKGHEKCALLILGETQDLGLINASNSALQMPLHIAARNGLATVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAISSFSFNLLKNCGIAAKTAACGALPNGSTCPYSKDRHNAIGLDGCYSE", "length": 1073, "header": "sp|Q5ZLC8-1|ANR52_CHICK Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Gallus gallus OX=9031 GN=ANKRD52 PE=2 SV=1 CANONICAL=Q5ZLC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Mass spectral data for 64 eluted peptides and structural modeling define peptide binding preferences for class I alleles in two chicken MHC-B haplotypes associated with opposite responses to Marek's disease.", "journal": "Immunogenetics", "date": "2008-09", "authors": "Sherman Mark A, Goto Ronald M, Moore Roger E, Hunt Henry D, Lee Terry D, Miller Marcia M", "evidence": [ { "database": "IEDB", "id": "423640", "url": "https://www.iedb.org/epitope/423640" } ], "reference": [ { "type": "PubMed", "id": "18612635", "url": "https://glygen.org/publication/PubMed/18612635" } ] } ], "pathway": [ { "id": "gga:426469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426469", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to ciliary inversin compartment", "id": "GO:1904108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904108", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLC8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1073, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLC8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLC8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 916, "end_pos": 918 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"monoisotopic_mass": 15762.0 }, "refseq": { "ac": "NP_001006570", "name": "golgin subfamily A member 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570" }, "gene_names": [ { "name": "GOLGA7", "type": "recommended", "evidence": [ { "id": "Q5ZLC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ] }, { "name": "GOLGA7", "type": "synonym", "evidence": [ { "id": "NP_001006570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570" } ] }, { "name": "RCJMB04_6k22", "type": "synonym", "evidence": [ { "id": "Q5ZLC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ] } ], "protein_names": [ { "name": "Golgin subfamily A member 7", "type": "recommended", "evidence": [ { "id": "Q5ZLC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9/entry#names_and_taxonomy" } ] }, { "name": "golgi autoantigen, golgin subfamily a, 7", "type": "synonym", "evidence": [ { "id": "NP_001006570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570" } ] }, { "name": "golgin subfamily A member 7", "type": "synonym", "evidence": [ { "id": "NP_001006570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01006476.1, CR387916.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000332.1. On Jan 13, 2005 this sequence version replaced XP_424399.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570" } ] }, { "annotation": "May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9", "locus": { "chromosome": "22", "start_pos": 2762081, "end_pos": 2758285, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018062", "url": "https://www.ensembl.org/id/ENSGALG00010018062" } ] } } ], "crossref": [ { "id": "Q5ZLC9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "426787", "url": "https://www.ncbi.nlm.nih.gov/gene/426787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426787", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426787", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEMRPQQ", "url": "https://omabrowser.org/oma/group/CEMRPQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLC9", "url": "https://www.orthodb.org/?gene=Q5ZLC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLC9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLC9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648002", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLC9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSGGTRCQFQSKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKIAKFIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR", "length": 137, "header": "sp|Q5ZLC9-1|GOGA7_CHICK Isoform 1 of Golgin subfamily A member 7 OS=Gallus gallus OX=9031 GN=GOLGA7 PE=2 SV=1 CANONICAL=Q5ZLC9-1" }, "isoforms": [ { "isoform_ac": "Q5ZLC9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9/entry#Q5ZLC9-1", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSGGTRCQFQSKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKIAKFIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR", "length": 137, "header": "sp|Q5ZLC9-1|GOGA7_CHICK Isoform 1 of Golgin subfamily A member 7 OS=Gallus gallus OX=9031 GN=GOLGA7 PE=2 SV=1 CANONICAL=Q5ZLC9-1" }, "locus": { "chromosome": "22", "start_pos": 2760096, "end_pos": 2758354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043679.1", "url": "https://www.ensembl.org/id/ENSGALT00010043679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025990.1", "url": "https://www.ensembl.org/id/ENSGALP00010025990.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:426787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426787", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9648002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648002", "resource": "Reactome", "description": "RAS processing" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U746-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "GOLGA7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MW90-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "Golga7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5EA55-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "GOLGA7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AYQ1-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "Golga7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRVDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z5G4-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "GOLGA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91W53-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "Golga7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR", "length": 137 }, "evidence": [ { "id": "Q5ZLC9", "url": "https://omabrowser.org/oma/group/Q5ZLC9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" }, { "name": "palmitoyltransferase complex", "id": "GO:0002178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002178", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "post-translational protein modification", "id": "GO:0043687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043687", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLC9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLC9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 137, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLC9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLC9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLD4-1", "uniprot_ac": "Q5ZLD4", "uniprot_id": "TMM11_CHICK", "mass": { "chemical_mass": 21734.0, "monoisotopic_mass": 21734.0 }, "refseq": { "ac": "NP_001026637", "name": "transmembrane protein 11, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026637" }, "gene_names": [ { "name": "TMEM11", "type": "recommended", "evidence": [ { "id": "Q5ZLD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ] }, { "name": "RCJMB04_6k9", "type": "synonym", "evidence": [ { "id": "Q5ZLD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ] }, { "name": "TMEM11", "type": "synonym", "evidence": [ { "id": "NP_001026637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026637" } ] } ], "protein_names": [ { "name": "Transmembrane protein 11, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q5ZLD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 11, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001026637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026637" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU386310.1, AJ719800.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Aug 8, 2005 this sequence version replaced XP_425236.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026637" } ] }, { "annotation": "Plays a role in mitochondrial morphogenesis.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM11", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4", "locus": { "chromosome": "14", "start_pos": 4540477, "end_pos": 4531979, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021610", "url": "https://www.ensembl.org/id/ENSGALG00010021610" } ] } } ], "crossref": [ { "id": "Q5ZLD4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004749", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004749", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427663", "url": "https://www.ncbi.nlm.nih.gov/gene/427663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427663", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IGNCLHK", "url": "https://omabrowser.org/oma/group/IGNCLHK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLD4", "url": "https://www.orthodb.org/?gene=Q5ZLD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15099:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15099:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLD4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLD4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLD4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAWGRRRAGPGSTNSGGGGRERVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 194, "header": "sp|Q5ZLD4-1|TMM11_CHICK Isoform 1 of Transmembrane protein 11, mitochondrial OS=Gallus gallus OX=9031 GN=TMEM11 PE=2 SV=1 CANONICAL=Q5ZLD4-1" }, "isoforms": [ { "isoform_ac": "Q5ZLD4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4/entry#Q5ZLD4-1", "sequence": { "sequence": "MAAWGRRRAGPGSTNSGGGGRERVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 194, "header": "sp|Q5ZLD4-1|TMM11_CHICK Isoform 1 of Transmembrane protein 11, mitochondrial OS=Gallus gallus OX=9031 GN=TMEM11 PE=2 SV=1 CANONICAL=Q5ZLD4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:427663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427663", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A535-1", "protein_name": "Transmembrane protein 11", "gene_name": "TMEM11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAWGRRRLGPGGGGPARERLSLAATDCYIVHEIYSGENAQDQFECELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTTVLAGTACLFTPLALPLDYSHYVSLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKVYELCAV", "length": 191 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5D7N3-1", "protein_name": "Transmembrane protein 11, mitochondrial", "gene_name": "TMEM11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAWGRRRLGPGSGGGGARERVSLSATDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTTVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYRLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELCAV", "length": 192 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0BN86-1", "protein_name": "Transmembrane protein 11, mitochondrial", "gene_name": "Tmem11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAWGRRRLGPGGGSSRERVSLSATDCYIVHEIYSGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKVYELYAV", "length": 190 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P17152-1", "protein_name": "Transmembrane protein 11, mitochondrial", "gene_name": "TMEM11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAWGRRRLGPGSSGGSARERVSLSATDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 192 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NWH5-1", "protein_name": "Transmembrane protein 11, mitochondrial", "gene_name": "tmem11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLGRRRGVPVNRERGVMAATECYIVHEIYNGENAQEQFEYELEQALEAQYRYIVIEPTRIGDETARWVAVGNCLHKTAVLAGAACLLTPLALPVEYSRYVALPAGALSLACATLYGISWQFDPCCKYQVEYDSQKLSRLPLHTLTSSTPVVLVRRDDVHRKRLHNTIALAALAYCAKKIYELYAV", "length": 187 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BK08-1", "protein_name": "Transmembrane protein 11, mitochondrial", "gene_name": "Tmem11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAWGRRRLGPGGGGSRERVSLSATDCYIVHEIYSGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKVYELYAV", "length": 190 }, "evidence": [ { "id": "Q5ZLD4", "url": "https://omabrowser.org/oma/group/Q5ZLD4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLD4", "url": "https://www.uniprot.org/uniprotkb/Q5ZLD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLD4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLD4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLD4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLG0-1", "uniprot_ac": "Q5ZLG0", "uniprot_id": "AACS_CHICK", "mass": { "chemical_mass": 74370.0, "monoisotopic_mass": 74370.0 }, "refseq": {}, "gene_names": [ { "name": "AACS", "type": "recommended", "evidence": [ { "id": "Q5ZLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0" } ] }, { "name": "RCJMB04_6g9", "type": "synonym", "evidence": [ { "id": "Q5ZLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0" } ] } ], "protein_names": [ { "name": "Acetoacetyl-CoA synthetase", "type": "recommended", "evidence": [ { "id": "Q5ZLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.16", "type": "synonym", "evidence": [ { "id": "Q5ZLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0#function" }, { "database": "UniProtKB", "id": "Q9D2R0", "url": "https://www.uniprot.org/uniprotkb/Q9D2R0#function" }, { "database": "UniProtKB", "id": "Q9JMI1", "url": "https://www.uniprot.org/uniprotkb/Q9JMI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AACS", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0", "locus": { "chromosome": "15", "start_pos": 4465956, "end_pos": 4504767, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020928", "url": "https://www.ensembl.org/id/ENSGALG00010020928" } ] } } ], "crossref": [ { "id": "Q5ZLG0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416811", "url": "https://www.ncbi.nlm.nih.gov/gene/416811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416811", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLG0", "url": "https://www.orthodb.org/?gene=Q5ZLG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42921:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42921:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLG0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLG0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "16117", "url": "https://www.rhea-db.org/rhea/16117", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLG0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSREPEIMESQVMWEPDSKRNTHMDRFRAAVAGSCGLRLANYNDLYQWSVESFADFWAEFWKYSNIVCSRLYDEVVDTSKSIADVPEWFKGSRLNYAENLLKHKDNDKIALYAAKEGKEEILKVTFEELRQAVALYAAAMRKMGVKIGDRVVGYLPNSIHAVEAMLAAASIGAIWSSTSPDFGINGVLDRFSQIQPKLIFSVEAVVYNGKEHNHLEKLLSVVKGLPDLKKVVVIPYVSSRETIDISKIPNSVFLEDFLATGKGDQAPQLEFEQLPFSHPLFIMYSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMSSNDIIMYYTTTGWMMWNWLVTALATGASVVLYDGSPLVPSPNVLWDLIDRLGITILGTGAKWLAVLEEKNLKPCETHNLQTLHTILSTGSPLKSQSYEYVYKHIKSSVLLGSISGGTDIISCFMGQNVTIPVYKGEIQARNLGMAVEAWNDEGKPVWGESGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCKINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVEAFEEVSDSLCVPQYNKDGEERVILFLKMASNHAFSEDLVKRIRDAIRVALSARHVPSLILETKGIPYTINGKKVEVAVKQIIAGKEVEQRGAFSNPETLDLYQNIPELQNF", "length": 667, "header": "sp|Q5ZLG0-1|AACS_CHICK Isoform 1 of Acetoacetyl-CoA synthetase OS=Gallus gallus OX=9031 GN=AACS PE=2 SV=1 CANONICAL=Q5ZLG0-1" }, "isoforms": [ { "isoform_ac": "Q5ZLG0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0/entry#Q5ZLG0-1", "sequence": { "sequence": "MSREPEIMESQVMWEPDSKRNTHMDRFRAAVAGSCGLRLANYNDLYQWSVESFADFWAEFWKYSNIVCSRLYDEVVDTSKSIADVPEWFKGSRLNYAENLLKHKDNDKIALYAAKEGKEEILKVTFEELRQAVALYAAAMRKMGVKIGDRVVGYLPNSIHAVEAMLAAASIGAIWSSTSPDFGINGVLDRFSQIQPKLIFSVEAVVYNGKEHNHLEKLLSVVKGLPDLKKVVVIPYVSSRETIDISKIPNSVFLEDFLATGKGDQAPQLEFEQLPFSHPLFIMYSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMSSNDIIMYYTTTGWMMWNWLVTALATGASVVLYDGSPLVPSPNVLWDLIDRLGITILGTGAKWLAVLEEKNLKPCETHNLQTLHTILSTGSPLKSQSYEYVYKHIKSSVLLGSISGGTDIISCFMGQNVTIPVYKGEIQARNLGMAVEAWNDEGKPVWGESGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCKINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVEAFEEVSDSLCVPQYNKDGEERVILFLKMASNHAFSEDLVKRIRDAIRVALSARHVPSLILETKGIPYTINGKKVEVAVKQIIAGKEVEQRGAFSNPETLDLYQNIPELQNF", "length": 667, "header": "sp|Q5ZLG0-1|AACS_CHICK Isoform 1 of Acetoacetyl-CoA synthetase OS=Gallus gallus OX=9031 GN=AACS PE=2 SV=1 CANONICAL=Q5ZLG0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLG0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLG0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:416811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416811", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLG0", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLH0-1", "uniprot_ac": "Q5ZLH0", "uniprot_id": "NXT2_CHICK", "mass": { "chemical_mass": 16162.0, "monoisotopic_mass": 16162.0 }, "refseq": { "ac": "NP_001006436", "name": "NTF2-related export protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006436" }, "gene_names": [ { "name": "NXT2", "type": "recommended", "evidence": [ { "id": "Q5ZLH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0" } ] }, { "name": "NXT2", "type": "synonym", "evidence": [ { "id": "NP_001006436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006436" } ] }, { "name": "RCJMB04_6d20", "type": "synonym", "evidence": [ { "id": "Q5ZLH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0" } ] } ], "protein_names": [ { "name": "NTF2-related export protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZLH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0/entry#names_and_taxonomy" } ] }, { "name": "NTF2-related export protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006436" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.181931.1, SRR12888493.28078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMN08016667 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Jan 13, 2005 this sequence version replaced XP_420318.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006436" } ] }, { "annotation": "Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NXT2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0", "locus": { "chromosome": "4", "start_pos": 13763932, "end_pos": 13772406, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015532", "url": "https://www.ensembl.org/id/ENSGALG00010015532" } ] } } ], "crossref": [ { "id": "Q5ZLH0", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008092", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008092", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422346", "url": "https://www.ncbi.nlm.nih.gov/gene/422346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045875", "database": "InterPro", "categories": [ 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLH0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASVDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGQEALNEFFEMLPSSEFQVNVLDCQPVHEQATQSQTTVLVVTCGTVKFDGNKQRYFNQNFLLTAQATSNSTVWKIASDCFRFQDWAN", "length": 141, "header": "sp|Q5ZLH0-1|NXT2_CHICK Isoform 1 of NTF2-related export protein 2 OS=Gallus gallus OX=9031 GN=NXT2 PE=2 SV=1 CANONICAL=Q5ZLH0-1" }, "isoforms": [ { "isoform_ac": "Q5ZLH0-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0/entry#Q5ZLH0-1", "sequence": { "sequence": "MAASVDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGQEALNEFFEMLPSSEFQVNVLDCQPVHEQATQSQTTVLVVTCGTVKFDGNKQRYFNQNFLLTAQATSNSTVWKIASDCFRFQDWAN", "length": 141, "header": "sp|Q5ZLH0-1|NXT2_CHICK Isoform 1 of NTF2-related export protein 2 OS=Gallus gallus OX=9031 GN=NXT2 PE=2 SV=1 CANONICAL=Q5ZLH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLH0", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH0" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422346", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLH9-1", "uniprot_ac": "Q5ZLH9", "uniprot_id": "CDV3_CHICK", "mass": { "chemical_mass": 21613.0, "monoisotopic_mass": 21613.0 }, "refseq": {}, "gene_names": [ { "name": "CDV3", "type": "recommended", "evidence": [ { "id": "Q5ZLH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH9" } ] }, { "name": "RCJMB04_6c13", "type": "synonym", "evidence": [ { "id": "Q5ZLH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH9" } ] } ], "protein_names": [ { "name": "Protein CDV3 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZLH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLH9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus 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CANONICAL=Q5ZLH9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska 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Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress (By similarity). May play a role as a molecular chaperone and participate in protein folding.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7#function" }, { "database": "UniProtKB", "id": "Q9JKR6", "url": "https://www.uniprot.org/uniprotkb/Q9JKR6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HYOU1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7", "locus": { "chromosome": "24", "start_pos": 5702619, "end_pos": 5717320, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024873", "url": "https://www.ensembl.org/id/ENSGALG00010024873" } ] } } ], "crossref": [ { "id": "Q5ZLK7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423727", "url": "https://www.iedb.org/epitope/423727", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428251", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLK7", "url": "https://www.orthodb.org/?gene=Q5ZLK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLK7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLK7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLK7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAPRWMLGWLLLACCVPHTEPLAVMSVDMGSESMKIAIVKPGVPMEIVLNKESRRKTPVAVALKENERLFGDSALGMSIKTPKVAFRYFQDLLGKQIDNPQVALYQSRFPEHELVKDEKRQTVIFKLSQTLQYSPEEMLGMVLNYSRGLAEEFAEQPIKDAVITVPAYFNQAERRAVLHAARMADLKVLQLINDNTAVALNYGVSGGKTSMPLHSFSFQNIMFYDMGAGSTVCTIVTYQTVKTKDSGTQPQLQIQGIGFDRTLGGLEMELRLRDYLAKLFNDQHPSKDVRKNPRAMAKLLKEANRLKTVLSANADHMAQIEGLLDDIDFKAKVSRQEFEDLCSDLFQRVPGPVQQALSSAEMNLDGIDQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFMVRDAAMFPIQVEFTREVEEDDKSKSLKHNKRILFQRMAPYPQRKVITFNRYTDDFEFYVNYGDLSFLNQDDLRIFGSLNLTTVRLKGVGESFKKHSDYESKGIKAHFNMDESGVLSLDRVESVFETLVEDKLEEESTLTKLGNTISSLFGGGGHTPEAGENLTDSVQEEEESLAEAAKEEQGVKQGQKSSAEDAGEEQGEEKQQSPHPDQAEAVPPKEESQKNEEGEKSEARDPKEDKETVNEEELSKSSGAGTAAKAEEEKKIKAPKKQKLVHEITMELDVNDVPDLLEDELKSSMKKLQDLTIRDLEKQEREKSANSLESFIFETQDKLYQEEYLFVSTEEEREEISKKLSEASNWMEEEGYAAATKELKDKLAELKKLCRNLFFRVEERRKWPERLAALESLLNHSNIFLKGARMIPESDQIFTEVELGTLEKAINETTVWKNETLAEQNKLSPAEKPVLLSKDIELKIAGLDREVQYLLDKAKFAKPKPKKEKNATKSDSGKNATGTSESENTIPPTEGKQEEKPEDISPAKEPPTTEKVVTDDEPGSDSSSKKEKKPEAGGESRKNDEL", "length": 1002, "header": "sp|Q5ZLK7-1|HYOU1_CHICK Isoform 1 of Hypoxia up-regulated protein 1 OS=Gallus gallus OX=9031 GN=HYOU1 PE=2 SV=1 CANONICAL=Q5ZLK7-1" }, "isoforms": [ { "isoform_ac": "Q5ZLK7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7/entry#Q5ZLK7-1", "sequence": { "sequence": "MARAPRWMLGWLLLACCVPHTEPLAVMSVDMGSESMKIAIVKPGVPMEIVLNKESRRKTPVAVALKENERLFGDSALGMSIKTPKVAFRYFQDLLGKQIDNPQVALYQSRFPEHELVKDEKRQTVIFKLSQTLQYSPEEMLGMVLNYSRGLAEEFAEQPIKDAVITVPAYFNQAERRAVLHAARMADLKVLQLINDNTAVALNYGVSGGKTSMPLHSFSFQNIMFYDMGAGSTVCTIVTYQTVKTKDSGTQPQLQIQGIGFDRTLGGLEMELRLRDYLAKLFNDQHPSKDVRKNPRAMAKLLKEANRLKTVLSANADHMAQIEGLLDDIDFKAKVSRQEFEDLCSDLFQRVPGPVQQALSSAEMNLDGIDQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFMVRDAAMFPIQVEFTREVEEDDKSKSLKHNKRILFQRMAPYPQRKVITFNRYTDDFEFYVNYGDLSFLNQDDLRIFGSLNLTTVRLKGVGESFKKHSDYESKGIKAHFNMDESGVLSLDRVESVFETLVEDKLEEESTLTKLGNTISSLFGGGGHTPEAGENLTDSVQEEEESLAEAAKEEQGVKQGQKSSAEDAGEEQGEEKQQSPHPDQAEAVPPKEESQKNEEGEKSEARDPKEDKETVNEEELSKSSGAGTAAKAEEEKKIKAPKKQKLVHEITMELDVNDVPDLLEDELKSSMKKLQDLTIRDLEKQEREKSANSLESFIFETQDKLYQEEYLFVSTEEEREEISKKLSEASNWMEEEGYAAATKELKDKLAELKKLCRNLFFRVEERRKWPERLAALESLLNHSNIFLKGARMIPESDQIFTEVELGTLEKAINETTVWKNETLAEQNKLSPAEKPVLLSKDIELKIAGLDREVQYLLDKAKFAKPKPKKEKNATKSDSGKNATGTSESENTIPPTEGKQEEKPEDISPAKEPPTTEKVVTDDEPGSDSSSKKEKKPEAGGESRKNDEL", "length": 1002, "header": "sp|Q5ZLK7-1|HYOU1_CHICK Isoform 1 of Hypoxia up-regulated protein 1 OS=Gallus gallus OX=9031 GN=HYOU1 PE=2 SV=1 CANONICAL=Q5ZLK7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 949, "start_aa": "Thr", "end_pos": 949, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr949", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Mass spectral data for 64 eluted peptides and structural modeling define peptide binding preferences for class I alleles in two chicken MHC-B haplotypes associated with opposite responses to Marek's disease.", "journal": "Immunogenetics", "date": "2008-09", "authors": "Sherman Mark A, Goto Ronald M, Moore Roger E, Hunt Henry D, Lee Terry D, Miller Marcia M", "evidence": [ { "database": "IEDB", "id": "423727", "url": "https://www.iedb.org/epitope/423727" } ], "reference": [ { "type": "PubMed", "id": "18612635", "url": "https://glygen.org/publication/PubMed/18612635" } ] } ], "pathway": [ { "id": "gga:428251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428251", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum chaperone complex", "id": "GO:0034663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034663", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" }, { "name": "negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway", "id": "GO:1903298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903298", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" }, { "start_pos": 926, "end_pos": 928, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLK7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1002, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLK7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLK7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZLK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLK7" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Prevents secretion from ER", "eco_id": "ECO_0000255", "start_pos": 999, "end_pos": 1002, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 949 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 835, "end_pos": 837 }, { "start_pos": 867, "end_pos": 869 }, { "start_pos": 874, "end_pos": 876 }, { "start_pos": 926, "end_pos": 928 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLL9-1", "uniprot_ac": "Q5ZLL9", "uniprot_id": "BRM1L_CHICK", "mass": { "chemical_mass": 37766.0, "monoisotopic_mass": 37766.0 }, "refseq": { "ac": "NP_001007936", "name": "breast cancer metastasis-suppressor 1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936" }, "gene_names": [ { "name": "BRMS1L", "type": "recommended", "evidence": [ { "id": "Q5ZLL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ] }, { "name": "BRMS1L", "type": "synonym", "evidence": [ { "id": "NP_001007936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936" } ] }, { "name": "RCJMB04_5j5", "type": "synonym", "evidence": [ { "id": "Q5ZLL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ] } ], "protein_names": [ { "name": "Breast cancer metastasis-suppressor 1-like protein", "type": "recommended", "evidence": [ { "id": "Q5ZLL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9/entry#names_and_taxonomy" } ] }, { "name": "BRMS1 like transcriptional repressor", "type": "synonym", "evidence": [ { "id": "NP_001007936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936" } ] }, { "name": "breast cancer metastasis-suppressor 1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001007936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719715.1, HAEK01037518.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Dec 15, 2004 this sequence version replaced XP_421245.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007936", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936" } ] }, { "annotation": "Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRMS1L", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9", "locus": { "chromosome": "5", "start_pos": 35880407, "end_pos": 35861260, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005909", "url": "https://www.ensembl.org/id/ENSGALG00010005909" } ] } } ], "crossref": [ { "id": "Q5ZLL9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "423328", "url": "https://www.ncbi.nlm.nih.gov/gene/423328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423328", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XIYRELC", "url": "https://omabrowser.org/oma/group/XIYRELC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLL9", "url": "https://www.orthodb.org/?gene=Q5ZLL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLL9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLL9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007936", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLL9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVHSREKKENNHDEMEVDYGENEGSTSEEEETESSSVSEEGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLAALQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKPEPPVKLEKHLHSARSEEGRLYYDGEWYGRGQTIYIDKKDECPTSAIITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHNHN", "length": 323, "header": "sp|Q5ZLL9-1|BRM1L_CHICK Isoform 1 of Breast cancer metastasis-suppressor 1-like protein OS=Gallus gallus OX=9031 GN=BRMS1L PE=2 SV=1 CANONICAL=Q5ZLL9-1" }, "isoforms": [ { "isoform_ac": "Q5ZLL9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9/entry#Q5ZLL9-1", "sequence": { "sequence": "MPVHSREKKENNHDEMEVDYGENEGSTSEEEETESSSVSEEGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLAALQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKPEPPVKLEKHLHSARSEEGRLYYDGEWYGRGQTIYIDKKDECPTSAIITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHNHN", "length": 323, "header": "sp|Q5ZLL9-1|BRM1L_CHICK Isoform 1 of Breast cancer metastasis-suppressor 1-like protein OS=Gallus gallus OX=9031 GN=BRMS1L PE=2 SV=1 CANONICAL=Q5ZLL9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423328", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A4FV29-1", "protein_name": "Breast cancer metastasis-suppressor 1-like protein", "gene_name": "BRMS1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "length": 323 }, "evidence": [ { "id": "Q5ZLL9", "url": "https://omabrowser.org/oma/group/Q5ZLL9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3Z9D3-1", "protein_name": "BRMS1 like transcriptional repressor", "gene_name": "Brms1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "length": 323 }, "evidence": [ { "id": "Q5ZLL9", "url": "https://omabrowser.org/oma/group/Q5ZLL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U1T3-1", "protein_name": "Breast cancer metastasis-suppressor 1-like protein", "gene_name": "Brms1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDRKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "length": 323 }, "evidence": [ { "id": "Q5ZLL9", "url": "https://omabrowser.org/oma/group/Q5ZLL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8V1-1", "protein_name": "Breast cancer metastasis-suppressor 1-like protein-A", "gene_name": "brms1la", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVHSREKKESNHEEMEVDFAEQEGSSSEDEDTESSSVSEDGESSEMDDEDCERRRMECIDEMTNLEKQFTDLKDQLYKERLNQVDAKLQEVMSGKAAEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYDCETQAAFQHWESEKLLLFDTVQTELEEKIRRLEEDRHSIDITSELWNDELQSRKNKKKDPFSPDKKKKPVVVSGPYIVYMLQDLDILEDWTAIRKAMATLGPHRVKTDASSKIDKLQHNARSEDGRLFYDGEWYSRGQAITIDKKDEYPTSAVITTINHDEVWFKRVDGSKSKLYVSQLQKGKYTVKHA", "length": 323 }, "evidence": [ { "id": "Q5ZLL9", "url": "https://omabrowser.org/oma/group/Q5ZLL9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5PSV4-1", "protein_name": "Breast cancer metastasis-suppressor 1-like protein", "gene_name": "BRMS1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "length": 323 }, "evidence": [ { "id": "Q5ZLL9", "url": "https://omabrowser.org/oma/group/Q5ZLL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLL9", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLL9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLN2-1", "uniprot_ac": "Q5ZLN2", "uniprot_id": "CCZ1_CHICK", "mass": { "chemical_mass": 55208.0, "monoisotopic_mass": 55208.0 }, "refseq": {}, "gene_names": [ { "name": "CCZ1", "type": "recommended", "evidence": [ { "id": "Q5ZLN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2" } ] }, { "name": "RCJMB04_5g18", "type": "synonym", "evidence": [ { "id": "Q5ZLN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2" } ] } ], "protein_names": [ { "name": "Vacuolar fusion protein CCZ1 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZLN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLN2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCZ1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2", "locus": { "chromosome": "14", "start_pos": 1015050, "end_pos": 1030079, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021827", "url": "https://www.ensembl.org/id/ENSGALG00010021827" } ] } } ], "crossref": [ { "id": "Q5ZLN2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416433", "url": "https://www.ncbi.nlm.nih.gov/gene/416433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416433", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLN2", "url": "https://www.orthodb.org/?gene=Q5ZLN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13056:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13056:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLN2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLN2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZLN2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLN2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKVLKERLEKFFHRYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHMEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 476, "header": "sp|Q5ZLN2-1|CCZ1_CHICK Isoform 1 of Vacuolar fusion protein CCZ1 homolog OS=Gallus gallus OX=9031 GN=CCZ1 PE=2 SV=1 CANONICAL=Q5ZLN2-1" }, "isoforms": [ { "isoform_ac": "Q5ZLN2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLN2/entry#Q5ZLN2-1", "sequence": { "sequence": "MATAAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKVLKERLEKFFHRYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHMEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 476, "header": "sp|Q5ZLN2-1|CCZ1_CHICK Isoform 1 of Vacuolar fusion protein CCZ1 homolog OS=Gallus gallus OX=9031 GN=CCZ1 PE=2 SV=1 CANONICAL=Q5ZLN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, 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"evidence": [ { "id": "Q5ZLS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2/entry#names_and_taxonomy" } ] }, { "name": "LSM16 homolog (EDC3, S. cerevisiae)", "type": "synonym", "evidence": [ { "id": "NP_001025556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556" } ] }, { "name": "YjeF domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZLS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2/entry#names_and_taxonomy" } ] }, { "name": "enhancer of mRNA decapping 3 homolog", "type": "synonym", "evidence": [ { "id": "NP_001025556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556" } ] }, { "name": "enhancer of mRNA-decapping protein 3", "type": "synonym", "evidence": [ { "id": "NP_001025556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556" } ] }, { "name": "yjeF domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001025556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719662.1, SRR13267650.2432.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001025556.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556" } ] }, { "annotation": "Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2#function" }, { "database": "UniProtKB", "id": "Q96F86", "url": "https://www.uniprot.org/uniprotkb/Q96F86#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EDC3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2", "locus": { "chromosome": "10", "start_pos": 2500676, "end_pos": 2474870, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021131", "url": "https://www.ensembl.org/id/ENSGALG00010021131" } ] } } ], "crossref": [ { "id": "Q5ZLS2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415294", "url": "https://www.ncbi.nlm.nih.gov/gene/415294", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025762", "database": "InterPro", "categories": [ 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13612:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLS2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLS2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025556", "database": 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"https://www.uniprot.org/uniprotkb/Q5ZLS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2" } ], "pmid": "" }, { "name": "deadenylation-independent decapping of nuclear-transcribed mRNA", "id": "GO:0031087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031087", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 98, "end_pos": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLS8-1", "uniprot_ac": "Q5ZLS8", "uniprot_id": "INT10_CHICK", "mass": { "chemical_mass": 81832.0, "monoisotopic_mass": 81832.0 }, "refseq": { "ac": "NP_001034386", "name": "integrator complex subunit 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034386" }, "gene_names": [ { "name": "INTS10", "type": "recommended", "evidence": [ { "id": "Q5ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8" } ] }, { "name": "INTS10", "type": "synonym", "evidence": [ { "id": "NP_001034386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034386" } ] }, { "name": "RCJMB04_4p16", "type": "synonym", "evidence": [ { "id": "Q5ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 10", "type": "recommended", "evidence": [ { "id": "Q5ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8/entry#names_and_taxonomy" } ] }, { "name": "Int10", "type": "synonym", "evidence": [ { "id": "Q5ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8/entry#names_and_taxonomy" } ] }, { "name": "int10", "type": "synonym", "evidence": [ { "id": "NP_001034386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034386" } ] }, { "name": "integrator complex subunit 10", "type": "synonym", "evidence": [ { "id": "NP_001034386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034386" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719656.1, HAEK01060485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Jan 31, 2006 this sequence version replaced XP_420454.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001034386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034386" } ] }, { "annotation": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. 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"MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 710, "header": "sp|Q5ZLS8-1|INT10_CHICK Isoform 1 of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=2 SV=1 CANONICAL=Q5ZLS8-1" }, "isoforms": [ { "isoform_ac": "Q5ZLS8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8/entry#Q5ZLS8-1", "sequence": { "sequence": "MSAQGDCEFLVKRARELVPGDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTASAGRLLYDMFVNFPDQPAVWREISVITAALRNDSQDKQTQFLRGLFETLPGRVQCEMLLKATEQCFNTLERAEMLLLLLRRFPETVVQHGVGLGETLLEAENIEDQESPVNCFRKLFVCDVLPLIINNPDVRLPASLLYKYLNKAAEFYINYVTRSTQTESQYQGSQDSSDLMSPSKRSSQKYIIDGLTEKSSQITDPWERLFKILSVVGMRCEWQMDKGRRSFGDILHRMKDLCRYISNFDSDAHAKYKNQVVYSTMLVFFKNAFQYVSNIQPSLFQGPNAPNQAPLILLEDVTNVYGDTDIDRNKHIHKKRKLAEGREKTMSSDDEDPSGKARSRHIAVNKADLANSIEVLESFKLARESWELLCSLESLDKEFTRICLSWKTETWLWLRIFLTDMIIYQGQYKKAISSLHHLAALQGSHSPQQITGQGSLENQRALIQLATCHFALGEYRQTCEKVLDLMCYILLPIQEGGKVQEEQPKVKSKFRKGSDLKLWPCTSRAIMPYCLHLLLACFKLRAFTDNRDDTALGHVIVLLQHEWPRGENLFLKAINKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLS", "length": 710, "header": "sp|Q5ZLS8-1|INT10_CHICK Isoform 1 of Integrator complex subunit 10 OS=Gallus gallus OX=9031 GN=INTS10 PE=2 SV=1 CANONICAL=Q5ZLS8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 664, "start_aa": "Thr", "end_pos": 664, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr664", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:422489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422489", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLS8", "url": "https://www.uniprot.org/uniprotkb/Q5ZLS8" } ], "pmid": "" } ] }, { "name": "Cellular 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"evidence": [ { "id": "Q5ZLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ] }, { "name": "RCJMB04_4o21", "type": "synonym", "evidence": [ { "id": "Q5ZLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ] } ], "protein_names": [ { "name": "NEDD4-binding protein 3 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3/entry#names_and_taxonomy" } ] }, { "name": "N4BP3 homolog", "type": "synonym", "evidence": [ { "id": "Q5ZLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3#function" }, { "database": "UniProtKB", "id": "A0A1L8GXY6", "url": "https://www.uniprot.org/uniprotkb/A0A1L8GXY6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "N4BP3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3", "locus": { "chromosome": "13", "start_pos": 9703868, "end_pos": 9708579, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012017", "url": "https://www.ensembl.org/id/ENSGALG00010012017" } ] } } ], "crossref": [ { "id": "Q5ZLT3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR033571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431542", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLT3", "url": "https://www.orthodb.org/?gene=Q5ZLT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32274", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32274", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32274:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32274:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:Q5ZLT3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLT3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLT3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAQGPVSCEPDTRVLGTYLSSVPIGSMGSVGSLVEKQDLSPLELRAPLGGTRGLRQPDGLLRKGPSQRELFGYLHGAKKETRSERKHQASAACYKRDYESDRENRSPERCSREHHRGADFSKSSLPERGRFDKCRIRPSAFKAVTGKGLVSMQGLSSSKGQKLSKSNGSLHTLLSQSTTAAPQHGPLRTHLLHAISLDEASDSSHNSIQSFPSYGSRLKPAQSQFSASMGHINHIGGSLDRVSRSPRDPLAPEKAPLSCKSMATLSRLQSPGEPPPPYEFTYSLEDAVKQLEDRLKETGGELRQLKRSLSETEDPFAQAFEDKQRLWLDELEDLKQMYMARLQQVTQQAQRGQRALQLQLYKAQQEKKRLQEELSMQQCQCEETKLRQSQGERVSPKLEETKWEVSPLLSLSVATLQAVQPGWGSGSLL", "length": 431, "header": "sp|Q5ZLT3-1|N4BP3_CHICK Isoform 1 of NEDD4-binding protein 3 homolog OS=Gallus gallus OX=9031 GN=N4BP3 PE=2 SV=1 CANONICAL=Q5ZLT3-1" }, "isoforms": [ { "isoform_ac": "Q5ZLT3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3/entry#Q5ZLT3-1", "sequence": { "sequence": "MAAAQGPVSCEPDTRVLGTYLSSVPIGSMGSVGSLVEKQDLSPLELRAPLGGTRGLRQPDGLLRKGPSQRELFGYLHGAKKETRSERKHQASAACYKRDYESDRENRSPERCSREHHRGADFSKSSLPERGRFDKCRIRPSAFKAVTGKGLVSMQGLSSSKGQKLSKSNGSLHTLLSQSTTAAPQHGPLRTHLLHAISLDEASDSSHNSIQSFPSYGSRLKPAQSQFSASMGHINHIGGSLDRVSRSPRDPLAPEKAPLSCKSMATLSRLQSPGEPPPPYEFTYSLEDAVKQLEDRLKETGGELRQLKRSLSETEDPFAQAFEDKQRLWLDELEDLKQMYMARLQQVTQQAQRGQRALQLQLYKAQQEKKRLQEELSMQQCQCEETKLRQSQGERVSPKLEETKWEVSPLLSLSVATLQAVQPGWGSGSLL", "length": 431, "header": "sp|Q5ZLT3-1|N4BP3_CHICK Isoform 1 of NEDD4-binding protein 3 homolog OS=Gallus gallus OX=9031 GN=N4BP3 PE=2 SV=1 CANONICAL=Q5ZLT3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:431542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431542", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT3", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 431, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLT3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 169, "end_pos": 171 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLT7-1", "uniprot_ac": "Q5ZLT7", "uniprot_id": "5MP2_CHICK", "mass": { "chemical_mass": 48019.0, "monoisotopic_mass": 48019.0 }, "refseq": { "ac": "NP_001006516", "name": "eIF5-mimic protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" }, "gene_names": [ { "name": "BZW1", "type": "recommended", "evidence": [ { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ] }, { "name": "5MP2", "type": "synonym", "evidence": [ { "id": "NP_001006516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" }, { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ] }, { "name": "BZW1", "type": "synonym", "evidence": [ { "id": "NP_001006516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" } ] }, { "name": "RCJMB04_4o16", "type": "synonym", "evidence": [ { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ] } ], "protein_names": [ { "name": "eIF5-mimic protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7/entry#names_and_taxonomy" } ] }, { "name": "Basic leucine zipper and W2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7/entry#names_and_taxonomy" } ] }, { "name": "basic leucine zipper and W2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" } ] }, { "name": "eIF5-mimic protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000591.1, HAEK01145191.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Jan 13, 2005 this sequence version replaced XP_421929.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006516", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516" } ] }, { "annotation": "Translation initiation regulator which may repress repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (By similarity). Enhances histone H4 gene transcription but does not seem to bind DNA directly (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7#function" }, { "database": "UniProtKB", "id": "Q7L1Q6", "url": "https://www.uniprot.org/uniprotkb/Q7L1Q6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BZW1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7", "locus": { "chromosome": "7", "start_pos": 10911905, "end_pos": 10899492, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024792", "url": "https://www.ensembl.org/id/ENSGALG00010024792" } ] } } ], "crossref": [ { "id": "Q5ZLT7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008220", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008220", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424073", "url": "https://www.ncbi.nlm.nih.gov/gene/424073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424073", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEFCLFR", "url": "https://omabrowser.org/oma/group/TEFCLFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLT7", "url": "https://www.orthodb.org/?gene=Q5ZLT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLT7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLT7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006516", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006516", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLT7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMTRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGILLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAVSLRKVNMDNRLMELFPANKQSVEHFSKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNISEQTVIAIIWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHLAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD", "length": 418, "header": "sp|Q5ZLT7-1|5MP2_CHICK Isoform 1 of eIF5-mimic protein 2 OS=Gallus gallus OX=9031 GN=BZW1 PE=2 SV=1 CANONICAL=Q5ZLT7-1" }, "isoforms": [ { "isoform_ac": "Q5ZLT7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7/entry#Q5ZLT7-1", "sequence": { "sequence": "MNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMTRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGILLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAVSLRKVNMDNRLMELFPANKQSVEHFSKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNISEQTVIAIIWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHLAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD", "length": 418, "header": "sp|Q5ZLT7-1|5MP2_CHICK Isoform 1 of eIF5-mimic protein 2 OS=Gallus gallus OX=9031 GN=BZW1 PE=2 SV=1 CANONICAL=Q5ZLT7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424073", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424073", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6P7P5-1", "protein_name": "eIF5-mimic protein 2", "gene_name": "Bzw1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD", "length": 419 }, "evidence": [ { "id": "Q5ZLT7", "url": "https://omabrowser.org/oma/group/Q5ZLT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PD83-1", "protein_name": "eIF5-mimic protein 2-A", "gene_name": "bzw1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNNQKQQKPTLTGQRFKTRKRDEKERFDPSQFQESIVQGLNQTGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLSDDLTRTEYCLFTASEDLETMQAYAQVFNKLIRRYKYLEKGFEEEIKKLLLFLKGFTESERNKLAMLTGILLANGNISASILNSLFNENLVKEGVSAAFAVKLFKSWINEKDINSVAASLRKVGMDNRLMELFPANKRSCEHFSKYFTDAGLKELSDFARNQQSIGARKELQKELQEQMSRGETLKDIIAYVREEMKKTSISEQTMIGIVWTSVMSSVEWNKKEELVTEQAIKHLKQYSPLLKAFTSQGLSELTLLLKIQEYCYDNIHFMKAFQKIVVLLYKADVLSEEVILKWYTEGHVAKGKSVFLEQMKKFVEWLKNAEEESESEEEEGD", "length": 419 }, "evidence": [ { "id": "Q5ZLT7", "url": "https://omabrowser.org/oma/group/Q5ZLT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7L1Q6-1", "protein_name": "eIF5-mimic protein 2", "gene_name": "BZW1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD", "length": 419 }, "evidence": [ { "id": "Q5ZLT7", "url": "https://omabrowser.org/oma/group/Q5ZLT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQC6-1", "protein_name": "eIF5-mimic protein 2", "gene_name": "Bzw1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD", "length": 419 }, "evidence": [ { "id": "Q5ZLT7", "url": "https://omabrowser.org/oma/group/Q5ZLT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLT7", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZLT7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 418, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZLT7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZLT7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZLT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLT7" }, { "id": "PRU00695", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00695" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000255", "start_pos": 246, "end_pos": 413, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLW2-1", "uniprot_ac": "Q5ZLW2", "uniprot_id": "ORAI2_CHICK", "mass": { "chemical_mass": 28955.0, "monoisotopic_mass": 28955.0 }, "refseq": { "ac": "NP_001025881", "name": "protein orai-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" }, "gene_names": [ { "name": "ORAI2", "type": "recommended", "evidence": [ { "id": "Q5ZLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2" } ] }, { "name": "ORAI2", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] }, { "name": "ORAI3", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] }, { "name": "RCJMB04_4k12", "type": "synonym", "evidence": [ { "id": "Q5ZLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2" } ] }, { "name": "TMEM142B", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" }, { "id": "Q5ZLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2" } ] } ], "protein_names": [ { "name": "Protein orai-2", "type": "recommended", "evidence": [ { "id": "Q5ZLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2/entry#names_and_taxonomy" } ] }, { "name": "ORAI calcium release-activated calcium modulator 3", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] }, { "name": "Transmembrane protein 142B", "type": "synonym", "evidence": [ { "id": "Q5ZLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2/entry#names_and_taxonomy" } ] }, { "name": "protein orai-2", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] }, { "name": "transmembrane protein 142B", "type": "synonym", "evidence": [ { "id": "NP_001025881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719622.1, SRR13267648.1488.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Nov 10, 2021 this sequence version replaced NP_001025881.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001025881", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881" } ] }, { "annotation": "Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ORAI2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2", "locus": {} } ], "crossref": [ { "id": "Q5ZLW2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001837", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001837", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417509", "url": "https://www.ncbi.nlm.nih.gov/gene/417509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417509", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZLW2", "url": "https://www.orthodb.org/?gene=Q5ZLW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLW2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLW2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025881", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLW2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLW2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 257, "header": "sp|Q5ZLW2-1|ORAI2_CHICK Isoform 1 of Protein orai-2 OS=Gallus gallus OX=9031 GN=ORAI2 PE=2 SV=1 CANONICAL=Q5ZLW2-1" }, "isoforms": [ { "isoform_ac": "Q5ZLW2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLW2/entry#Q5ZLW2-1", "sequence": { "sequence": "MSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 257, "header": "sp|Q5ZLW2-1|ORAI2_CHICK Isoform 1 of Protein orai-2 OS=Gallus gallus OX=9031 GN=ORAI2 PE=2 SV=1 CANONICAL=Q5ZLW2-1" }, "locus": {} } ], 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZLX5-1", "uniprot_ac": "Q5ZLX5", "uniprot_id": "ZRAB2_CHICK", "mass": { "chemical_mass": 37863.0, "monoisotopic_mass": 37863.0 }, "refseq": { "ac": "NP_001026468", "name": "zinc finger Ran-binding domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" }, "gene_names": [ { "name": "ZRANB2", "type": "recommended", "evidence": [ { "id": "Q5ZLX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ] }, { "name": "RCJMB04_4i6", "type": "synonym", "evidence": [ { "id": "Q5ZLX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ] }, { "name": "ZNF265", "type": "synonym", "evidence": [ { "id": "NP_001026468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] }, { "name": "ZRANB2", "type": "synonym", "evidence": [ { "id": "NP_001026468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] } ], "protein_names": [ { "name": "Zinc finger Ran-binding domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZLX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger Ran-binding domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001026468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] }, { "name": "zinc finger protein 265", "type": "synonym", "evidence": [ { "id": "NP_001026468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] }, { "name": "zinc finger, RAN-binding domain containing 2", "type": "synonym", "evidence": [ { "id": "NP_001026468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888544.94799.1, HAEK01060083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992533 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On or before Dec 11, 2020 this sequence version replaced XP_015146542.1, XP_422543.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468" } ] }, { "annotation": "May regulate alternative splicing by interfering with constitutive 5'-splice site selection.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5#function" }, { "database": "UniProtKB", "id": "O95218", "url": "https://www.uniprot.org/uniprotkb/O95218#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZRANB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5", "locus": { "chromosome": "8", "start_pos": 28796527, "end_pos": 28808341, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023917", "url": "https://www.ensembl.org/id/ENSGALG00010023917" } ] } } ], "crossref": [ { "id": "Q5ZLX5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZLX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011340", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424717", "url": "https://www.ncbi.nlm.nih.gov/gene/424717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424717", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WICPDID", "url": "https://omabrowser.org/oma/group/WICPDID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZLX5", "url": "https://www.orthodb.org/?gene=Q5ZLX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12999:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12999:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZLX5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZLX5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZLX5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKPVGPASILKEVEDKESEGEDEEDEDGDLSKYKLDEDEDEDDADLSKYNLDASEEEDTNKKKKSNRRSRSKSRSSHSRSSSRSSSHSSSRSRSRSHSRSSSSSRSRSRSSSREHSRSRGSKSRSSSRSYRGSSTPRKRSYSSSRSSSSPERSKKRSRSRSSSSGDRKKRRSRSRSPERRRRSSSGSSHSGSRTSSKKK", "length": 334, "header": "sp|Q5ZLX5-1|ZRAB2_CHICK Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ZRANB2 PE=2 SV=1 CANONICAL=Q5ZLX5-1" }, "isoforms": [ { "isoform_ac": "Q5ZLX5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5/entry#Q5ZLX5-1", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKPVGPASILKEVEDKESEGEDEEDEDGDLSKYKLDEDEDEDDADLSKYNLDASEEEDTNKKKKSNRRSRSKSRSSHSRSSSRSSSHSSSRSRSRSHSRSSSSSRSRSRSSSREHSRSRGSKSRSSSRSYRGSSTPRKRSYSSSRSSSSPERSKKRSRSRSSSSGDRKKRRSRSRSPERRRRSSSGSSHSGSRTSSKKK", "length": 334, "header": "sp|Q5ZLX5-1|ZRAB2_CHICK Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ZRANB2 PE=2 SV=1 CANONICAL=Q5ZLX5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424717", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6Z7B1-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "zranb2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGKSFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENLVYNEREESDGEYDEFGRIKKKFRGKTKKDSDKKEEPKKVDQDDEEEDDDDEDGDLSKYKLDDDDEDDDDDDDDEDDADLSKYDLDDGDEKKGSHSGSSRSSSRSSSSSSRSRSRSRSRSSSSSRSRSRSRSKSRSSSRSGKGSASSKKRSRSPSSSPEGGQKRSRSRSSSGGRKKRRARSHSSERFGVTHGVLDTRRPSALYTGLSDKTVHD", "length": 324 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6RSB3-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSSKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERHHRSPSGSSHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35986-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "Zranb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERHHRSSSGSTHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95218-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q19QU3-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSTSRERSRSRGSKSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSTGDPKKRRTRSRSPERHHRSSSGSSHSGSRSSSKKK", "length": 328 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9AST1-1", "protein_name": "Transcription initiation factor TFIID subunit 15", "gene_name": "TAF15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGYPTNGSVYVSNLPLGTDENMLADYFGTIGLLKRDKRTGTPKVWLYRDKETDEPKGDATVTYEDPHAALAAVEWFNNKDFHGNTIGVFMAESKNKNAGDAVEFVEFDGGAEETNGGAGRGRGQADSSAKPWQQDGDWMCPNTSCTNVNFAFRGVCNRCGTARPAGASGGSMGAGRGRGRGGGADGGAPGKQPSGAPTGLFGPNDWACPMCGNVNWAKRLKCNICNTNKPGQNEGGVRGGRGGGYKELDEQELEETKRRRREAEEDDGEMYDEFGNLKKKYRVKTNQADTRPAVAAGRAGWEVEELGIDKDGRERSRDRQRDRGRDHHYDKDRRRSRSRERERGKERDYDYDHDRDRDRDYGRERGSRYRN", "length": 372 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9R020-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "Zranb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERHHRSSSGSTHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "Q5ZLX5", "url": "https://omabrowser.org/oma/group/Q5ZLX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "pmid": "" }, { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q5ZLX5", "url": "https://www.uniprot.org/uniprotkb/Q5ZLX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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138, "header": "sp|Q5ZM31-1|T170A_CHICK Isoform 1 of Transmembrane protein 170A OS=Gallus gallus OX=9031 GN=TMEM170A PE=2 SV=1 CANONICAL=Q5ZM31-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 26, "start_aa": "Asn", "end_pos": 26, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "Q5ZM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM31#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, 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The reference sequence was derived from JAENSK010000329.1. 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Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425543", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZM33", "url": "https://www.orthodb.org/?gene=Q5ZM33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZM33", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZM33", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006560", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006560", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZM33-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDLSEAEPVHHKALPLLTGTQLIHTDKLSEKAEDDTMPIRRSVNSSRETPPKSKPAEGGEEVKADAEATSEESASAGEEQENETLPAAAPSEAEQPKEPENEEKGETKSSVETKKDDKDQSKEKEKKVKKTIPAWATLSASQLARAQKQTQMAATSRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELERGIIRQVKGKGASGSFVVVSNAGKTVQKARDRKKSTSVSTPEQQVKLEDILPLAFTRLCEPKEASYSLIKKYVSQYYPKLKVDIRPQLLKNALQRAVEKGQLEQITGKGASGTFQLKKSGEKPLLGGTLMEDAILSAIAAMNEPKTCSTTALKKYILENHPGTNSNFQVHLLKRTLQRCEKNGWLEQISGKGFSGTFQLCFPYYPSPDVLYPEKQQDEDSEESQEEEEEESEEEEESEEEESEEEEPPPKKRMQKRPPPKSRSRAPPMKRRESKPKPRKTPAAHQGKAKPPPKVKTPVKKAKPAAPAIKKPSGGSSSKKPTASGRKEVKPSAKGKSAMRKSLRAKK", "length": 559, "header": "sp|Q5ZM33-1|HP1B3_CHICK Isoform 1 of Heterochromatin protein 1-binding protein 3 OS=Gallus gallus OX=9031 GN=HP1BP3 PE=2 SV=1 CANONICAL=Q5ZM33-1" }, "isoforms": [ { "isoform_ac": "Q5ZM33-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33/entry#Q5ZM33-1", "sequence": { "sequence": "MATDLSEAEPVHHKALPLLTGTQLIHTDKLSEKAEDDTMPIRRSVNSSRETPPKSKPAEGGEEVKADAEATSEESASAGEEQENETLPAAAPSEAEQPKEPENEEKGETKSSVETKKDDKDQSKEKEKKVKKTIPAWATLSASQLARAQKQTQMAATSRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELERGIIRQVKGKGASGSFVVVSNAGKTVQKARDRKKSTSVSTPEQQVKLEDILPLAFTRLCEPKEASYSLIKKYVSQYYPKLKVDIRPQLLKNALQRAVEKGQLEQITGKGASGTFQLKKSGEKPLLGGTLMEDAILSAIAAMNEPKTCSTTALKKYILENHPGTNSNFQVHLLKRTLQRCEKNGWLEQISGKGFSGTFQLCFPYYPSPDVLYPEKQQDEDSEESQEEEEEESEEEEESEEEESEEEEPPPKKRMQKRPPPKSRSRAPPMKRRESKPKPRKTPAAHQGKAKPPPKVKTPVKKAKPAAPAIKKPSGGSSSKKPTASGRKEVKPSAKGKSAMRKSLRAKK", "length": 559, "header": "sp|Q5ZM33-1|HP1B3_CHICK Isoform 1 of Heterochromatin protein 1-binding protein 3 OS=Gallus gallus OX=9031 GN=HP1BP3 PE=2 SV=1 CANONICAL=Q5ZM33-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:425543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425543", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM33", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZM33-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 559, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZM33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZM33" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZM33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" }, { "id": "PRU00837", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "H15 1", "eco_id": "ECO_0000255", "start_pos": 158, "end_pos": 233, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZM33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" }, { "id": "PRU00837", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "H15 2", "eco_id": "ECO_0000255", "start_pos": 256, "end_pos": 331, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZM33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" }, { "id": "PRU00837", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "H15 3", "eco_id": "ECO_0000255", "start_pos": 339, "end_pos": 414, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZM33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM33" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "PxVxL motif", "eco_id": "ECO_0000250", "start_pos": 256, "end_pos": 260, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 46, "end_pos": 48 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZM41-1", "uniprot_ac": "Q5ZM41", "uniprot_id": "TEX10_CHICK", "mass": { "chemical_mass": 105390.0, "monoisotopic_mass": 105390.0 }, "refseq": {}, "gene_names": [ { "name": "TEX10", "type": "recommended", "evidence": [ { "id": "Q5ZM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41" } ] }, { "name": "RCJMB04_3d16", "type": "synonym", "evidence": [ { "id": "Q5ZM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 10 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM41", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41#function" }, { "database": "UniProtKB", "id": "Q9NXF1", "url": "https://www.uniprot.org/uniprotkb/Q9NXF1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZM41", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEX10", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41", "locus": { "chromosome": "2", "start_pos": 88791296, "end_pos": 88744548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008303", "url": "https://www.ensembl.org/id/ENSGALG00010008303" } ] } } ], "crossref": [ { "id": "Q5ZM41", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZM41", "database": "AlphaFoldDB", "categories": [] }, { "id": "420993", "url": "https://www.ncbi.nlm.nih.gov/gene/420993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420993", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420993", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZM41", "url": "https://www.orthodb.org/?gene=Q5ZM41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZM41", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZM41", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZM41", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZM41-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKKRKHQEDFQKVKLKVGKKKPKLENATDTTFKTKAIQIPEQLKEDGMLTTQNRKLNIKDLLSQMHHYSPGVKQNALLGLKDLLSQYPFLIDAHLSNIISEVAAVFTDKDSGVRGAAVHLLQFLASKIRAEQIAPFFPLVSAHLSSAMTHISEGIQEDSLKVLDILLEAYPALLTDRSSILLKNFVELISHQQLSKRLKSKEKLSWMLSVNPNRRVTSQQWRLNVLIRLKKFLQAVVDGSNETEDEGLQEQKDSPHSVRNPIFISWKVHANNQQHIHLYENGGLRPKMSSSFRLRSLASVMDSAEKGLSSAENLKGFIEIIIPLLIECWIEASPAQSAPILGNLLESDCQQLMQQVLSIIHLLWKLTKRHDETYKMEVWLRMNYLVDFKHHFMRNFPYSLQETVKHKKKDSCKGNKYCTTSSNNVDHLLLNLTLCDIMVSLASASTLQADSGWLDMIRNFVTDTLQDGSRLNSKQVNRLLGVTWRLMQIQQNKVATEPLIKAVYTLYQQRNLLFPVRTLLLKFFSRVYQKEDSKTQRIRSRSKVLSRWLAGLPQQLALLGLRNPELSNQLIDIIHSAASRSNKELLQSLQATAVQIYDPLGGTLVLLPAEAQRRLVQLVYFLPCLPTSLLACLSRCCIMGRMSSELAATLIGILRMRSSFAGWKCQVQDNAVNDVDYFSFLFSTLIGFSREELTSLQGIRGKPHISQTQLSPVRLYLTDLDQFLHHWAVTEVICHSLSTIPSQSQCFDILQTGICKYLVGLVVIPDSTAGSVLCAINKLLDQACILSENLHKFLASCCYSLLYFLLTLDKEDAEHVQKRDMLWGSCISALALLPRLLRLMLQSLQVSRICREELPVVAQLLRLLMQHGQLRSHMMTNEFLVQQIIKDIMTLKSGEVQEQWLTDLHYCFNIYLASHPQGPSPMNAVY", "length": 927, "header": "sp|Q5ZM41-1|TEX10_CHICK Isoform 1 of Testis-expressed protein 10 homolog OS=Gallus gallus OX=9031 GN=TEX10 PE=2 SV=1 CANONICAL=Q5ZM41-1" }, "isoforms": [ { "isoform_ac": "Q5ZM41-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM41/entry#Q5ZM41-1", "sequence": { "sequence": 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The reference sequence was derived from AJ719513.1. On Jan 13, 2005 this sequence version replaced XP_417091.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006275" } ] }, { "annotation": "Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUPT20H", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71", "locus": { "chromosome": "1", "start_pos": 172195771, "end_pos": 172158609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006246", "url": "https://www.ensembl.org/id/ENSGALG00010006246" } ] } } ], "crossref": [ { "id": "Q5ZM71", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZM71", "database": "AlphaFoldDB", "categories": [] }, { "id": "418896", "url": "https://www.ncbi.nlm.nih.gov/gene/418896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418896", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZM71", "url": "https://www.orthodb.org/?gene=Q5ZM71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13526", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13526", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13526:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13526:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZM71", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZM71", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZM71-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418896", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418896", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71" } ], "pmid": "" }, { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM71", "url": "https://www.uniprot.org/uniprotkb/Q5ZM71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { 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"url": "https://www.uniprot.org/uniprotkb/Q5ZM86" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 50", "type": "recommended", "evidence": [ { "id": "Q5ZM86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in EGFR signaling.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM86", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZM86", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC50", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86", "locus": { "chromosome": "9", "start_pos": 13352375, "end_pos": 13397907, 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"MAEIGIDQSKLPGVKEVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQEHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 301, "header": "sp|Q5ZM86-1|CCD50_CHICK Isoform 1 of Coiled-coil domain-containing protein 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=2 SV=1 CANONICAL=Q5ZM86-1" }, "isoforms": [ { "isoform_ac": "Q5ZM86-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86/entry#Q5ZM86-1", "sequence": { "sequence": "MAEIGIDQSKLPGVKEVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQEHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 301, "header": "sp|Q5ZM86-1|CCD50_CHICK Isoform 1 of Coiled-coil domain-containing protein 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=2 SV=1 CANONICAL=Q5ZM86-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZM86", "url": "https://www.uniprot.org/uniprotkb/Q5ZM86" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424906", "resource": "KEGG Pathway" } ], "orthologs": [], 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"https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZM86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZM86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMB2-1", "uniprot_ac": "Q5ZMB2", "uniprot_id": "HEBP1_CHICK", "mass": { "chemical_mass": 21105.0, "monoisotopic_mass": 21105.0 }, "refseq": { "ac": "NP_001025925", "name": "heme-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025925" }, "gene_names": [ { "name": "HEBP1", "type": "recommended", "evidence": [ { "id": "Q5ZMB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ] }, { "name": "HEBP1", "type": "synonym", "evidence": [ { "id": "NP_001025925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025925" } ] }, { "name": "RCJMB04_2k3", "type": "synonym", "evidence": [ { "id": "Q5ZMB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ] } ], "protein_names": [ { "name": "Heme-binding protein 1", "type": "recommended", "evidence": [ { "id": "Q5ZMB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2/entry#names_and_taxonomy" } ] }, { "name": "heme-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001025925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025925" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719472.1, SRR13267659.150093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Aug 8, 2005 this sequence version replaced XP_416201.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025925" } ] }, { "annotation": "May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HEBP1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2", "locus": { "chromosome": "1", "start_pos": 48281112, "end_pos": 48291462, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010995", "url": "https://www.ensembl.org/id/ENSGALG00010010995" } ] } } ], "crossref": [ { "id": "Q5ZMB2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417961", "url": "https://www.ncbi.nlm.nih.gov/gene/417961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q5ZMB2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q5ZMB2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR006917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417961", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYEERTY", "url": "https://omabrowser.org/oma/group/AYEERTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMB2", "url": "https://www.orthodb.org/?gene=Q5ZMB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMB2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMB2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMB2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGMIKNSLLSTVETWPYRVLSKGEKEQLSYEERECEGGQFAVVEVTGKPFDEASKEAALKLLKYVGGSNDKGAGMGMTAPVSITAFPAEDGSLQQKVKVYLRIPNQFQASPPCPSDESIKIEERQGMTIYSTQFGGYAKEVDYVNYAAKLKTALGSEAAYRKDFYFCNGYDPPMKPYGRRNEVWFVKE", "length": 189, "header": "sp|Q5ZMB2-1|HEBP1_CHICK Isoform 1 of Heme-binding protein 1 OS=Gallus gallus OX=9031 GN=HEBP1 PE=2 SV=1 CANONICAL=Q5ZMB2-1" }, "isoforms": [ { "isoform_ac": "Q5ZMB2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2/entry#Q5ZMB2-1", "sequence": { "sequence": "MLGMIKNSLLSTVETWPYRVLSKGEKEQLSYEERECEGGQFAVVEVTGKPFDEASKEAALKLLKYVGGSNDKGAGMGMTAPVSITAFPAEDGSLQQKVKVYLRIPNQFQASPPCPSDESIKIEERQGMTIYSTQFGGYAKEVDYVNYAAKLKTALGSEAAYRKDFYFCNGYDPPMKPYGRRNEVWFVKE", "length": 189, "header": "sp|Q5ZMB2-1|HEBP1_CHICK Isoform 1 of Heme-binding protein 1 OS=Gallus gallus OX=9031 GN=HEBP1 PE=2 SV=1 CANONICAL=Q5ZMB2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:417961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B4F7C7-1", "protein_name": "Heme-binding protein 1", "gene_name": "Hebp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGMIRNSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPISFAVFPNEDGSLQKKLKVWFRIPNQFQGSPPTPSDQSVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVKV", "length": 190 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HB42-1", "protein_name": "Heme-binding protein 1", "gene_name": "Hebp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLGMIRNSLFGSVETWPWQVLSTGGKEEVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGIGMGMTVPISFAVFPNEDGSLQKKLKVWFRIPNQFQSSPPVPGDESVKIEEREGITVYSTQFSGYAKEADYIAHATQLRTALEGTTATYQGDLYYCTGYDPPMKPYGRRNEVWLVKT", "length": 190 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q148C9-1", "protein_name": "Heme-binding protein 1", "gene_name": "HEBP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGMIKNSLFGSVETWPWQVLSKGSKGDVFYEERACEGGKFATVEVTDKPVDEALREAMPKVMKYVGGSNDKGLGMGMTVPISFAVFPSDDGDLQKKLKVWFRIPNKFQSDPPAPSDDSIKIEDREGITVYSTQFGGYAKAADYAAQAAQLRSALESTAKYQTDFYFCTGYDPPMKPYGRRNEVWLVKSSE", "length": 191 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5ISC6-1", "protein_name": "Heme-binding protein 1", "gene_name": "HEBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLGMIKNSLFGSVETWPWQVLSKGDKQDISYEERACEGGKFATVEMTDKPVDEALREAMPKVMKYVGGSNDKGIGMGMTVPISFAVFPSDGGSLQKKLKVWFRIPNEFQSNPPVPSDDSIKIEERESITVYSLQFGGYAKEADYVARAAQLRTALEGIATCRSDVYFCTGYDPPMKPYGRRNEVWLVKA", "length": 189 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NRV9-1", "protein_name": "Heme-binding protein 1", "gene_name": "HEBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGMIKNSLFGSVETWPWQVLSKGDKEEVAYEERACEGGKFATVEVTDKPVDEALREAMPKVAKYAGGTNDKGIGMGMTVPISFAVFPNEDGSLQKKLKVWFRIPNQFQSDPPAPSDKSVKIEEREGITVYSMQFGGYAKEADYVAQATRLRAALEGTATYRGDIYFCTGYDPPMKPYGRRNEIWLLKT", "length": 189 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R257-1", "protein_name": "Heme-binding protein 1", "gene_name": "Hebp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGMIRNSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPVSFALFPNEDGSLQKKLKVWFRIPNQFQGSPPAPSDESVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVKA", "length": 190 }, "evidence": [ { "id": "Q5ZMB2", "url": "https://omabrowser.org/oma/group/Q5ZMB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMB2-F1", "pdb_chain": "global", "start_pos": 1, 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"function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719467.1, HAEK01009344.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Nov 9, 2021 this sequence version replaced NP_001006315.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006315", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006315" } ] }, { "annotation": "Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PNRC2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7", "locus": { "chromosome": "23", "start_pos": 5988875, "end_pos": 5972814, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015555", "url": "https://www.ensembl.org/id/ENSGALG00010015555" } ] } } ], "crossref": [ { "id": "Q5ZMB7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "419688", "url": "https://www.ncbi.nlm.nih.gov/gene/419688", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419688", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419688", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMB7", "url": "https://www.orthodb.org/?gene=Q5ZMB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15365", "database": "Pfam", "categories": [ "Protein 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"https://www.uniprot.org/uniprotkb/Q5ZMB7/entry#Q5ZMB7-1", "sequence": { "sequence": "MVGGERFNIPVPQSRNITKNHQQLKNRQKNKDQNSQMKKTYMKKERGHGCNSLSGAWQAMQKAGKNNVHFPCNQNWSPNLSNRNLFFSPQTNQNYAGAKFSEPPSPSVLPKPPSHWVPVSFKPSDKEIMTFQLKTLLKVQA", "length": 141, "header": "sp|Q5ZMB7-1|PNRC2_CHICK Isoform 1 of Proline-rich nuclear receptor coactivator 2 OS=Gallus gallus OX=9031 GN=PNRC2 PE=2 SV=1 CANONICAL=Q5ZMB7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419688", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419688", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMB7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": 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Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMC3", "url": "https://www.orthodb.org/?gene=Q5ZMC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46573:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46573:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04564", "url": 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SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. 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"protein_names": [ { "name": "14-3-3 protein theta", "type": "recommended", "evidence": [ { "id": "Q5ZMD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMD1/entry#names_and_taxonomy" } ] }, { "name": "14-3-3 protein theta", "type": "synonym", "evidence": [ { "id": "NP_001006415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006415" } ] }, { "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide", "type": "synonym", "evidence": [ { "id": "NP_001006415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006415" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719453.1, HAEK01012593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000066.1. On Nov 22, 2004 this sequence version replaced XP_419945.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006415" } ] }, { "annotation": "Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. 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"categories": [ "Protein Classification" ] }, { "id": "PTHR18860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00002yez", "url": "https://www.rcsb.org/structure/pdb_00002yez", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "2YEZ", "url": "https://www.rcsb.org/structure/2YEZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMD1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMD1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMD1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKMQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 245, "header": "sp|Q5ZMD1-1|1433T_CHICK Isoform 1 of 14-3-3 protein theta OS=Gallus gallus OX=9031 GN=YWHAQ PE=1 SV=1 CANONICAL=Q5ZMD1-1" }, "isoforms": [ { "isoform_ac": "Q5ZMD1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMD1/entry#Q5ZMD1-1", "sequence": { "sequence": "MDKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKMQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 245, "header": "sp|Q5ZMD1-1|1433T_CHICK Isoform 1 of 14-3-3 protein theta OS=Gallus gallus OX=9031 GN=YWHAQ PE=1 SV=1 CANONICAL=Q5ZMD1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMD1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMD1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.", "journal": "eLife", "date": "2015-04-10", "authors": "Chappell Paul, Meziane El Kahina, Harrison Michael, Magiera \u0141ukasz, Hermann Clemens, Mears Laura, Wrobel Antony G, Durant Charlotte, Nielsen Lise Lotte, Buus S\u00f8ren, Ternette Nicola, Mwangi William, Butter Colin, Nair Venugopal, Ahyee Trudy, Duggleby Richard, Madrigal Alejandro, Roversi Pietro, Lea Susan M, Kaufman Jim", "evidence": [ { "database": "IEDB", "id": "419384", "url": "https://www.iedb.org/epitope/419384" } ], "reference": [ { "type": "PubMed", "id": "25860507", "url": "https://glygen.org/publication/PubMed/25860507" } ] } ], "pathway": [ { "id": "gga:421932", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421932", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QM17-1", "protein_name": "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta", "gene_name": "YWHAQ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1. Direct regulator of SIRT1.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5#function" }, { "database": "UniProtKB", "id": "Q86WX3", "url": "https://www.uniprot.org/uniprotkb/Q86WX3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS19BP1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5", "locus": { "chromosome": "1", "start_pos": 50633450, "end_pos": 50630061, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012378", "url": "https://www.ensembl.org/id/ENSGALG00010012378" } ] } } ], "crossref": [ { "id": "Q5ZMG5", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "418011", "url": "https://www.ncbi.nlm.nih.gov/gene/418011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418011", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMG5", "url": "https://www.orthodb.org/?gene=Q5ZMG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31454:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31454:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15684", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15684", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMG5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMG5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMG5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASLIRRGLELLEAPGQGKAPPALQQGRDGTRPAGTARRRKVTAGPGKNKATIKGRVVKSAIEEYHKKKAVNHLKANLLYMTSGRCVADKAVTQQVLTQNRGRKSKDRPAEKKEKKKPEGTVFTEEDFRKFEREYFGIP", "length": 140, "header": "sp|Q5ZMG5-1|AROS_CHICK Isoform 1 of Active regulator of SIRT1 OS=Gallus gallus OX=9031 GN=RPS19BP1 PE=2 SV=1 CANONICAL=Q5ZMG5-1" }, "isoforms": [ { "isoform_ac": "Q5ZMG5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5/entry#Q5ZMG5-1", "sequence": { "sequence": "MSASLIRRGLELLEAPGQGKAPPALQQGRDGTRPAGTARRRKVTAGPGKNKATIKGRVVKSAIEEYHKKKAVNHLKANLLYMTSGRCVADKAVTQQVLTQNRGRKSKDRPAEKKEKKKPEGTVFTEEDFRKFEREYFGIP", "length": 140, "header": "sp|Q5ZMG5-1|AROS_CHICK Isoform 1 of Active regulator of SIRT1 OS=Gallus gallus OX=9031 GN=RPS19BP1 PE=2 SV=1 CANONICAL=Q5ZMG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418011", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMG5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 140, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMG5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMI4-1", "uniprot_ac": "Q5ZMI4", "uniprot_id": "MVP_CHICK", "mass": { "chemical_mass": 93822.0, "monoisotopic_mass": 93822.0 }, "refseq": { "ac": "NP_001006336", "name": "major vault protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006336" }, "gene_names": [ { "name": "MVP", "type": "recommended", "evidence": [ { "id": "Q5ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4" } ] }, { "name": "MVP", "type": "synonym", "evidence": [ { "id": "NP_001006336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006336" } ] }, { "name": "RCJMB04_1p8", "type": "synonym", "evidence": [ { "id": "Q5ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4" } ] } ], "protein_names": [ { "name": "Major vault protein", "type": "recommended", "evidence": [ { "id": "Q5ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4/entry#names_and_taxonomy" } ] }, { "name": "MVP", "type": "synonym", "evidence": [ { "id": "Q5ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4/entry#names_and_taxonomy" } ] }, { "name": "major vault protein", "type": "synonym", "evidence": [ { "id": "NP_001006336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006336" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719400.1, SRR13267649.250729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000373.1. On Sep 23, 2021 this sequence version replaced NP_001006336.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006336" } ] }, { "annotation": "Structural component of the vault particle, which is a massive ribonucleoprotein complex that may play a role in cargo transport and signal transduction (By similarity). Vaults may play a role in nucleo-cytoplasmic transport (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4#function" }, { "database": "UniProtKB", "id": "Q14764", "url": "https://www.uniprot.org/uniprotkb/Q14764#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MVP", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4", "locus": { "chromosome": "28", "start_pos": 429425, "end_pos": 419324, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028247", "url": "https://www.ensembl.org/id/ENSGALG00010028247" } ] } } ], "crossref": [ { "id": "Q5ZMI4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08825", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08825", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420049", "url": "https://www.ncbi.nlm.nih.gov/gene/420049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420049", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMI4", "url": "https://www.orthodb.org/?gene=Q5ZMI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMI4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMI4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMI4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMI4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDPVIRIPPYHYIHVLDLNSNVTRVEVGPHSFIRQDHERVVFSPKRMVMVPPRHYCVVLNPVARGPTGAVLFDGAGQAQLRHADLDIRLTQEPFPLYPGEELQQGVTPLQVVLADTALRLRALLDFEDEDGNKFVAGDEWLFEGPGTYIPHKEVEVVETLQATIIRHNQAIRLRARKECLDRQGTRRVTGEEWLVKRVGAYLPGVYEEVVDVVDAYVLTDKKALHLRATRTFEDVQGHVRRTGEEWLVTQEQSEAYVPDVFEEVVAEVLVTTLGPRQYCVVLDPVGPNGQPQLGQQRVVKGEKSFFLQPGERLQAGIQDVYVLSEDEGLLLQALQTIKDTDEDGTEVIRRAGDRWLARGPLEYVPPAEVTVLERRQALALAENEGIYVRDIRTGKVRVVTGQTYMLTESEELWEKELPPGVEVLLAEARGDTAGQDSGIQSSSGPSFGVQERDRTRAVTYQVPHNAAVQVYDYRERRARVVLGPELVVLGPGEQLTVLSLSGGRPKRPHARRSLCLRLGPDFCADIVTIETADHARLQLQLAYNWHFEVPEDPKALGRLFSVPDFVGDACKALASRVRGAVAAVTFDDFHKNSNRLICSAVFGFDEGGRLREHLRFVPNGLVVTSVDIQSVEPVDQRTRDALQRSVQLAIEIATNSQEAAARHEAERLAQEARVRLERQRLLDQAEAERARRELLELEALSAAVESAGAARAEAQARAEAARIEAEAAILQAKLKAEAVAIETEAELARLERMQAQEVRAQRARAEAEAARAQALAAVEASKVREVAAALGPETIRDIARAGPELQVKLLQGLGLQSALITDGAAPLNLFSTARGLLGLAVPPEPSTS", "length": 849, "header": "sp|Q5ZMI4-1|MVP_CHICK Isoform 1 of Major vault protein OS=Gallus gallus OX=9031 GN=MVP PE=2 SV=1 CANONICAL=Q5ZMI4-1" }, "isoforms": [ { "isoform_ac": "Q5ZMI4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4/entry#Q5ZMI4-1", "sequence": { "sequence": "MEDPVIRIPPYHYIHVLDLNSNVTRVEVGPHSFIRQDHERVVFSPKRMVMVPPRHYCVVLNPVARGPTGAVLFDGAGQAQLRHADLDIRLTQEPFPLYPGEELQQGVTPLQVVLADTALRLRALLDFEDEDGNKFVAGDEWLFEGPGTYIPHKEVEVVETLQATIIRHNQAIRLRARKECLDRQGTRRVTGEEWLVKRVGAYLPGVYEEVVDVVDAYVLTDKKALHLRATRTFEDVQGHVRRTGEEWLVTQEQSEAYVPDVFEEVVAEVLVTTLGPRQYCVVLDPVGPNGQPQLGQQRVVKGEKSFFLQPGERLQAGIQDVYVLSEDEGLLLQALQTIKDTDEDGTEVIRRAGDRWLARGPLEYVPPAEVTVLERRQALALAENEGIYVRDIRTGKVRVVTGQTYMLTESEELWEKELPPGVEVLLAEARGDTAGQDSGIQSSSGPSFGVQERDRTRAVTYQVPHNAAVQVYDYRERRARVVLGPELVVLGPGEQLTVLSLSGGRPKRPHARRSLCLRLGPDFCADIVTIETADHARLQLQLAYNWHFEVPEDPKALGRLFSVPDFVGDACKALASRVRGAVAAVTFDDFHKNSNRLICSAVFGFDEGGRLREHLRFVPNGLVVTSVDIQSVEPVDQRTRDALQRSVQLAIEIATNSQEAAARHEAERLAQEARVRLERQRLLDQAEAERARRELLELEALSAAVESAGAARAEAQARAEAARIEAEAAILQAKLKAEAVAIETEAELARLERMQAQEVRAQRARAEAEAARAQALAAVEASKVREVAAALGPETIRDIARAGPELQVKLLQGLGLQSALITDGAAPLNLFSTARGLLGLAVPPEPSTS", "length": 849, "header": "sp|Q5ZMI4-1|MVP_CHICK Isoform 1 of Major vault protein OS=Gallus gallus OX=9031 GN=MVP PE=2 SV=1 CANONICAL=Q5ZMI4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej 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"lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMI4" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MVP shoulder", "eco_id": "ECO_0000250", "start_pos": 520, "end_pos": 635, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 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], "function": [ { "annotation": "Acts as an inhibitor of protein phosphatase PP2A (By similarity). Together with TOPBP1, plays an essential role in the response to genome instability generated by the presence of acentric chromosome fragments derived from shattered chromosomes within micronuclei (By similarity). The CIP2A-TOPBP1 complex tethers chromosome fragments during mitosis to ensure clustered segregation of the fragments to a single daughter cell nucleus, facilitating re-ligation with limited chromosome scattering and loss (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7#function" }, { "database": "UniProtKB", "id": "Q8TCG1", "url": "https://www.uniprot.org/uniprotkb/Q8TCG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CIP2A", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7", "locus": { "chromosome": "1", "start_pos": 87776519, "end_pos": 87809749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004934", "url": "https://www.ensembl.org/id/ENSGALG00010004934" } ] } } ], "crossref": [ { "id": "Q5ZMJ7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "418410", "url": "https://www.ncbi.nlm.nih.gov/gene/418410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418410", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMJ7", "url": "https://www.orthodb.org/?gene=Q5ZMJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23161:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23161:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMJ7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMJ7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7", "database": 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OS=Gallus gallus OX=9031 GN=CIP2A PE=2 SV=2 CANONICAL=Q5ZMJ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418410", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ7" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ7", "url": 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The reference sequence was derived from JAENSK010000339.1. On Sep 23, 2021 this sequence version replaced NP_001026665.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026665" } ] }, { "annotation": "Involved in pre-mRNA splicing and processing events.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRRM1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9", "locus": { "chromosome": "23", "start_pos": 2890802, "end_pos": 2908253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015914", "url": 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"MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRDSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 888, "header": "sp|Q5ZMJ9-1|SRRM1_CHICK Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=2 SV=1 CANONICAL=Q5ZMJ9-1" }, "isoforms": [ { "isoform_ac": "Q5ZMJ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9/entry#Q5ZMJ9-1", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPTAFLELKKEEIKQRQIEQEKLASMKKQDEDKEKRDKEDKDNREKRDRSRSPRRRKSRSPSPRRRSSPIRRERKRSHSRSPHHRTKSRSATPAPEKKEATPEPEPSVKPKETVVQEATSNSDIPKAPKSEPPVPETKEISPERNSKKEREKEKEKTRQRSPTRSKSRSRSRSRSPSHSRPRRRHRSRSRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTVSSPPRKTRRLSPSASPPRRRHRPSPPASPPPKPRRSPTPQQSNRARKSRGSVSPGRASAPKHKSTEKRESPSPAPKPRKAELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEEERPKRSNVKNGEVGRRRRHSHSRSPSPSPRKRQKEPSPRRRRRSPSPPPARRRRSPSPPPPPRRRRSPSLPRRRSPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPQSKRRVSHSPPPKQRSSPAAKRRSPSISSKHRKGSPPSRSNRETRSPPQNKRDSPSPRPRASHTSSSPPPLRRGASASPQRRQSPSPSTRPIRRVSRTPEPKKTKASTPSPRSARRVSSSRSASGSPEPAPKKHQGPPSPARSRSPSANWSPAKKAKSPTQSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAAVAAAPAAVAAADTTSAQEEQEAETEPKKETESEPEDNLDDLEKHLREKALRSMRKAQVSPPS", "length": 888, "header": "sp|Q5ZMJ9-1|SRRM1_CHICK Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Gallus gallus OX=9031 GN=SRRM1 PE=2 SV=1 CANONICAL=Q5ZMJ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428216", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMJ9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMK7-1", "uniprot_ac": "Q5ZMK7", "uniprot_id": "UFM1_CHICK", "mass": { "chemical_mass": 9087.0, "monoisotopic_mass": 9087.0 }, "refseq": { "ac": "NP_001025998", "name": "ubiquitin-fold modifier 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998" }, "gene_names": [ { "name": "UFM1", "type": "recommended", "evidence": [ { "id": "Q5ZMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7" } ] }, { "name": "RCJMB04_1l24", "type": "synonym", "evidence": [ { "id": "Q5ZMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7" } ] }, { "name": "UBFM1", "type": "synonym", "evidence": [ { "id": "NP_001025998", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998" } ] }, { "name": "UFM1", "type": "synonym", "evidence": [ { "id": "NP_001025998", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998" } ] } ], "protein_names": [ { "name": "Ubiquitin-fold modifier 1", "type": "recommended", "evidence": [ { "id": "Q5ZMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-fold modifier 1", "type": "synonym", "evidence": [ { "id": "NP_001025998", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01046911.1, HAEK01000217.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992484, SAMN06140853 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000027.1. On Aug 8, 2005 this sequence version replaced XP_417088.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998" } ] }, { "annotation": "Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7#function" }, { "database": "UniProtKB", "id": "P61960", "url": "https://www.uniprot.org/uniprotkb/P61960#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UFM1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7", "locus": { "chromosome": "1", "start_pos": 171455356, "end_pos": 171467676, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002355", "url": "https://www.ensembl.org/id/ENSGALG00010002355" } ] } } ], "crossref": [ { "id": "Q5ZMK7", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017042", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01766", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01766", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418894", "url": "https://www.ncbi.nlm.nih.gov/gene/418894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418894", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418894", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEHAVGK", "url": "https://omabrowser.org/oma/group/MEHAVGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMK7", "url": "https://www.orthodb.org/?gene=Q5ZMK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15825", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15825", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15825:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15825:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMK7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMK7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025998", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMK7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKVTFKVTLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSDLRIIPRDRVGSS", "length": 85, "header": "sp|Q5ZMK7-1|UFM1_CHICK Isoform 1 of Ubiquitin-fold modifier 1 OS=Gallus gallus OX=9031 GN=UFM1 PE=3 SV=1 CANONICAL=Q5ZMK7-1" }, "isoforms": [ { "isoform_ac": "Q5ZMK7-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7/entry#Q5ZMK7-1", "sequence": { "sequence": "MSKVTFKVTLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSDLRIIPRDRVGSS", "length": 85, "header": "sp|Q5ZMK7-1|UFM1_CHICK Isoform 1 of Ubiquitin-fold modifier 1 OS=Gallus gallus OX=9031 GN=UFM1 PE=3 SV=1 CANONICAL=Q5ZMK7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMK7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMK7" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418894", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418894", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MV84-1", "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "Ufm1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC", "length": 85 }, "evidence": [ { "id": "Q5ZMK7", "url": "https://omabrowser.org/oma/group/Q5ZMK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A8DYH2-1", "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "Ufm1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKVTFKITLTSDPKLPFKVLSVPEGTPFTAVLKFASEEFKVPAETSAIITDDGIGISPQQTAGNVFLKHGSELRLIPRDRVGHQLS", "length": 87 }, "evidence": [ { "id": "Q5ZMK7", "url": "https://omabrowser.org/oma/group/Q5ZMK7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B0G186-1", "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "ufm1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKVTFKITLTSDPKLPFRVINVTEDTPFTAVLRFACEQFNVPWQTSAIITNDGIGINPAQTSGNIFLKNGSDLRLIPRDRVGGL", "length": 85 }, "evidence": [ { "id": "Q5ZMK7", "url": "https://omabrowser.org/oma/group/Q5ZMK7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P61960-1", "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "UFM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC", "length": 85 }, "evidence": [ { "id": "Q5ZMK7", "url": "https://omabrowser.org/oma/group/Q5ZMK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61961-1", "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "Ufm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026003" } ] }, { "name": "protein morgana", "type": "synonym", "evidence": [ { "id": "NP_001026003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026003" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.115574.1, AJ719370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000027.1. On Aug 8, 2005 this sequence version replaced XP_417203.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026003" } ] }, { "annotation": "Regulates centrosome duplication.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHORDC1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4", "locus": { "chromosome": "1", "start_pos": 187533361, "end_pos": 187467982, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007375", "url": "https://www.ensembl.org/id/ENSGALG00010007375" } ] } } ], "crossref": [ { "id": "Q5ZML4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZML4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06488", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06488", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419009", "url": "https://www.ncbi.nlm.nih.gov/gene/419009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419009", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGYTCCK", "url": "https://omabrowser.org/oma/group/KGYTCCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZML4", "url": "https://www.orthodb.org/?gene=Q5ZML4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46983:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46983:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04968", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04968", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZML4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZML4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZML4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLCYNRGCGQRFDPETNTEDSCTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGLHNSEKPPEPVKPDVKSTTERKELAELKPKFQEHIIQAPKPLETIKRPSPDEPMTNLQLKVSASLKQALDKLKLSSENEEKKEEDSDEIKIGTPCKNAGCSKTYQGPHSTEEVCQYHSGVPIFHEGMKYWSCCKRKTSDFNTFLAQEGCTTGTHVWTKKDAGKKVVPCRHDWHQTGGEVTVSIYAKNSVPDLSYVEANSTMLNIHIVFEGEKEFHRNVKLWGVIDVKRSYVNMTATKIEVSMRKAEPLLWASLELPVSNTQQTNENSDQ", "length": 331, "header": "sp|Q5ZML4-1|CHRD1_CHICK Isoform 1 of Cysteine and histidine-rich domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHORDC1 PE=2 SV=1 CANONICAL=Q5ZML4-1" }, "isoforms": [ { "isoform_ac": "Q5ZML4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4/entry#Q5ZML4-1", "sequence": { "sequence": "MSLLCYNRGCGQRFDPETNTEDSCTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGLHNSEKPPEPVKPDVKSTTERKELAELKPKFQEHIIQAPKPLETIKRPSPDEPMTNLQLKVSASLKQALDKLKLSSENEEKKEEDSDEIKIGTPCKNAGCSKTYQGPHSTEEVCQYHSGVPIFHEGMKYWSCCKRKTSDFNTFLAQEGCTTGTHVWTKKDAGKKVVPCRHDWHQTGGEVTVSIYAKNSVPDLSYVEANSTMLNIHIVFEGEKEFHRNVKLWGVIDVKRSYVNMTATKIEVSMRKAEPLLWASLELPVSNTQQTNENSDQ", "length": 331, "header": "sp|Q5ZML4-1|CHRD1_CHICK Isoform 1 of Cysteine and histidine-rich domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHORDC1 PE=2 SV=1 CANONICAL=Q5ZML4-1" }, "locus": { "chromosome": "1", "start_pos": 187479848, "end_pos": 187468071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017562.1", "url": "https://www.ensembl.org/id/ENSGALT00010017562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009706.1", "url": "https://www.ensembl.org/id/ENSGALP00010009706.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QMC4-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "CHORDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIAGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPRFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDSDEIKVGTSCKNGGCSKTYQGPQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHAWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKNQEKQKEDTAE", "length": 332 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A4T9-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "Chordc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLCYNRGCGQRFDPEANADDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEEDKKEEDSDEIKIGTSCKNGGCSKTYQGLQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTRGKHVWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVEANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPTTKKQEKQKDIAD", "length": 331 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I8H9-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "Chordc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALLCYNRGCGQRFDPEANADDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGTEEDKKEEDSDEIKIGTSCKNGGCSKTYQGLQSLDEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTKGKHVWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVEANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPTAKKQEKQKEDIAD", "length": 332 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q29RL2-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "CHORDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDSDEIKIGTSCKNGGCSKTYQGPQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKTEEKQKEETTE", "length": 332 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D1P4-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "Chordc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLCYNRGCGQRFDPEANSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGSEEDKKEEDSDEIKIGTSCKNGGCSKTYQGLQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTRGKHVWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVEANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPTTKKQEKQKDIAD", "length": 331 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHD1-1", "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "CHORDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELCELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDNDEIKIGTSCKNGGCSKTYQGLESLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTKGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLLNVHIVFEGEKEFDQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKKQEKQKDATTD", "length": 332 }, "evidence": [ { "id": "Q5ZML4", "url": "https://omabrowser.org/oma/group/Q5ZML4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "regulation of cellular response to heat", "id": "GO:1900034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900034", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML4", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZML4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 331, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZML4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZML4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00734", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00734" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHORD 1", "eco_id": "ECO_0000255", "start_pos": 5, "end_pos": 64, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00734", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00734" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHORD 2", "eco_id": "ECO_0000255", "start_pos": 157, "end_pos": 216, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00547", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00547" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CS", "eco_id": "ECO_0000255", "start_pos": 227, "end_pos": 316, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4#function" }, { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00734", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00734" } ], "binding_site_uniprot": 10, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 10, "end_pos": 10, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4#function" }, { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00734", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00734" } ], "binding_site_uniprot": 157, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "3", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 157, "end_pos": 157, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4#function" }, { "id": "Q5ZML4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML4" }, { "id": "PRU00734", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00734" } ], 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[ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ719369.1. On Apr 14, 2009 this sequence version replaced NP_001074364.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001131123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001131123" } ] }, { "annotation": "Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5#function" }, { "database": "UniProtKB", "id": "Q3MHD2", "url": "https://www.uniprot.org/uniprotkb/Q3MHD2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LSM12", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5", "locus": { "chromosome": "27", "start_pos": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776864", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEGELYC", "url": "https://omabrowser.org/oma/group/FEGELYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZML5", "url": "https://www.orthodb.org/?gene=Q5ZML5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13542", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13542", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZML5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZML5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001131123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001131123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZML5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGECFSVGSQVSCRTCQEQRLQGEVVAFDYPSKMLALKCPSSSGKPNHADILLVNLQYVSEVEIINDRTETPPPLASLNVSKLANKARMEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVIAPPYQVENCKGKEGSALGHVRKIVEKHFRDVESQKVMQRSQAQQTQKESALSS", "length": 194, "header": "sp|Q5ZML5-1|LSM12_CHICK Isoform 1 of Protein LSM12 OS=Gallus gallus OX=9031 GN=LSM12 PE=2 SV=1 CANONICAL=Q5ZML5-1" }, "isoforms": [ { "isoform_ac": "Q5ZML5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5/entry#Q5ZML5-1", "sequence": { "sequence": "MAAPGECFSVGSQVSCRTCQEQRLQGEVVAFDYPSKMLALKCPSSSGKPNHADILLVNLQYVSEVEIINDRTETPPPLASLNVSKLANKARMEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVIAPPYQVENCKGKEGSALGHVRKIVEKHFRDVESQKVMQRSQAQQTQKESALSS", "length": 194, "header": "sp|Q5ZML5-1|LSM12_CHICK Isoform 1 of Protein LSM12 OS=Gallus gallus OX=9031 GN=LSM12 PE=2 SV=1 CANONICAL=Q5ZML5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:776864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776864", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GM11-1", "protein_name": "LSM12 homolog", "gene_name": "Lsm12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS", "length": 195 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FFA0-1", "protein_name": "LSM12 homolog", "gene_name": "LSM12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS", "length": 195 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0VCF9-1", "protein_name": "Protein LSM12", "gene_name": "LSM12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS", "length": 195 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3MHD2-1", "protein_name": "Protein LSM12", "gene_name": "LSM12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS", "length": 195 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PBA2-1", "protein_name": "Protein LSM12 homolog A", "gene_name": "lsm12a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAPGPGEYFSVGSHVSCLTCLGQRLQGEVVAFDYPSKMLTLKCPSSSGKPNLSDVILINLAYVSEVDIINDRTETPPPLASLNISKLANRARTEKEDKLSQAYAISAGVSIEGQQLFQTIHKTIKDCKWQEKNIIVMDDVVISPPYQVENCKGKEGSALSHIRKIVEKHFRDVESQKTMQRSQAQQTQKDSSLSS", "length": 196 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D0R8-1", "protein_name": "Protein LSM12", "gene_name": "Lsm12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS", "length": 195 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYR0-1", "protein_name": "LSM12 homolog A", "gene_name": "Lsm12a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAAAASAVNAVNDCFSIGSTVVCTTCFNEEVEGEVLAFDHNTKMLILKCRSKSTEELSDIYAMNLSLCSNVQVIKECNGNFDDPQKLNLEQVKMRLRKTVERRQDYLKSKNADVSPEAQELYRAIAKQYGYNEVSWQGLNIQILNEVTISPPYRVDNVVSSSNNETSCNYIKRIIKQFFNTRPSPVPESGAAASTSSPSVSPTSSSLASGSPVPAN", "length": 217 }, "evidence": [ { "id": "Q5ZML5", "url": "https://omabrowser.org/oma/group/Q5ZML5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML5", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZML5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZML5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZML5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" }, { "id": "PRU01345", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01345" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AD", "eco_id": "ECO_0000255", "start_pos": 79, "end_pos": 173, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5ZML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML5" }, { "id": "PRU01346", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01346" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000255", "start_pos": 1, "end_pos": 71, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZML6-1", "uniprot_ac": "Q5ZML6", "uniprot_id": "MIMS1_CHICK", "mass": { "chemical_mass": 30449.0, "monoisotopic_mass": 30449.0 }, "refseq": { "ac": "NP_001026185", "name": "protein FAM210A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" }, "gene_names": [ { "name": "MIMS1", "type": "recommended", "evidence": [ { "id": "Q5ZML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6" } ] }, { "name": "C18orf19", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] }, { "name": "C2H18ORF19", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] }, { "name": "FAM210A", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" }, { "id": "Q5ZML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6" } ] }, { "name": "HsT2329", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] }, { "name": "RCJMB04_1k21", "type": "synonym", "evidence": [ { "id": "Q5ZML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6" } ] } ], "protein_names": [ { "name": "Mitochondrial inner membrane scaffold 1", "type": "recommended", "evidence": [ { "id": "Q5ZML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM210A", "type": "synonym", "evidence": [ { "id": "Q5ZML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6/entry#names_and_taxonomy" } ] }, { "name": "protein FAM210A", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] }, { "name": "uncharacterized protein C18orf19 homolog", "type": "synonym", "evidence": [ { "id": "NP_001026185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719368.1, AJ448729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000042.1. On Sep 23, 2021 this sequence version replaced NP_001026185.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026185", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185" } ] }, { "annotation": "Mitochondrial inner membrane protein essential for mitochondrial homeostasis, structural integrity, and cellular metabolism. Regulates mitochondrial translation by modulating protein synthesis of mitochondrial DNA-encoded genes.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML6", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6#function" }, { "database": "UniProtKB", "id": "Q8BGY7", "url": "https://www.uniprot.org/uniprotkb/Q8BGY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZML6", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6", "locus": {} } ], "crossref": [ { "id": "Q5ZML6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZML6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013887", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421045", "url": "https://www.ncbi.nlm.nih.gov/gene/421045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421045", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZML6", "url": "https://www.orthodb.org/?gene=Q5ZML6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21377:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21377:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZML6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZML6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026185", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026185", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZML6", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZML6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRSVLHTASQLAHGMCLLFPRTGAFRGLKGPSVSSNVGCKVILALDPPKRCLHAGAALFASKSSAVSSQPADTPRKVPEEREPLTSATEVPKQSPVESDASDPDPLQDKSISLVQRFKKTFKQYGKVMIPVHLVTSTVWFGSFYYAAMKGVNVVPFLELIGLPDSIVDILKNSQSGNALTAYALYKIATPARYTVTLGGTSITVKYLRKNGYMSTPPPVKEYLQDRMEETKDKITEKMEETKDKITEKMEETKDKITEKIQETKDKVSFKKIKD", "length": 275, "header": "sp|Q5ZML6-1|MIMS1_CHICK Isoform 1 of Mitochondrial inner membrane scaffold 1 OS=Gallus gallus OX=9031 GN=MIMS1 PE=2 SV=1 CANONICAL=Q5ZML6-1" }, "isoforms": [ { "isoform_ac": "Q5ZML6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6/entry#Q5ZML6-1", "sequence": { "sequence": "MQRSVLHTASQLAHGMCLLFPRTGAFRGLKGPSVSSNVGCKVILALDPPKRCLHAGAALFASKSSAVSSQPADTPRKVPEEREPLTSATEVPKQSPVESDASDPDPLQDKSISLVQRFKKTFKQYGKVMIPVHLVTSTVWFGSFYYAAMKGVNVVPFLELIGLPDSIVDILKNSQSGNALTAYALYKIATPARYTVTLGGTSITVKYLRKNGYMSTPPPVKEYLQDRMEETKDKITEKMEETKDKITEKMEETKDKITEKIQETKDKVSFKKIKD", "length": 275, "header": "sp|Q5ZML6-1|MIMS1_CHICK Isoform 1 of Mitochondrial inner membrane scaffold 1 OS=Gallus gallus OX=9031 GN=MIMS1 PE=2 SV=1 CANONICAL=Q5ZML6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZML6", "url": "https://www.uniprot.org/uniprotkb/Q5ZML6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:421045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421045", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", 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Required for Wnt signaling activation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5#function" }, { "database": "UniProtKB", "id": "Q9D115", "url": "https://www.uniprot.org/uniprotkb/Q9D115#function" }, { "database": "UniProtKB", "id": "Q9Y5V0", "url": "https://www.uniprot.org/uniprotkb/Q9Y5V0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF706", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5", "locus": { "chromosome": "2", "start_pos": 128305851, "end_pos": 128312646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011751", 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"https://www.ebi.ac.uk/interpro/entry/IPR045230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768824", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDQKGAA", "url": "https://omabrowser.org/oma/group/CDQKGAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMM5", "url": "https://www.orthodb.org/?gene=Q5ZMM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21213:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21213:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04419", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04419", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMM5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMM5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001091000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMM5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGQQKIQSQQKNAKKQAEQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA", "length": 76, "header": "sp|Q5ZMM5-1|ZN706_CHICK Isoform 1 of Transcriptional regulator ZNF706 OS=Gallus gallus OX=9031 GN=ZNF706 PE=3 SV=1 CANONICAL=Q5ZMM5-1" }, "isoforms": [ { "isoform_ac": "Q5ZMM5-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5/entry#Q5ZMM5-1", "sequence": { "sequence": "MARGQQKIQSQQKNAKKQAEQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA", "length": 76, "header": "sp|Q5ZMM5-1|ZN706_CHICK Isoform 1 of Transcriptional regulator ZNF706 OS=Gallus gallus OX=9031 GN=ZNF706 PE=3 SV=1 CANONICAL=Q5ZMM5-1" }, "locus": { "chromosome": "2", "start_pos": 128309813, "end_pos": 128308975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028118.1", "url": "https://www.ensembl.org/id/ENSGALT00010028118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016126.1", "url": "https://www.ensembl.org/id/ENSGALP00010016126.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:768824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768824", "resource": "KEGG Pathway" }, { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FLV5-1", "protein_name": "Zinc finger protein 706", "gene_name": "ZNF706", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARGQQKIQSQQKNAKKQAGQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA", "length": 76 }, "evidence": [ { "id": "Q5ZMM5", "url": "https://omabrowser.org/oma/group/Q5ZMM5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D115-1", "protein_name": "Transcriptional regulator ZNF706", "gene_name": "Znf706", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGQQKIQSQQKNAKKQAGQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA", "length": 76 }, "evidence": [ { "id": "Q5ZMM5", "url": "https://omabrowser.org/oma/group/Q5ZMM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5V0-1", "protein_name": "Transcriptional regulator ZNF706", "gene_name": "ZNF706", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGQQKIQSQQKNAKKQAGQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA", "length": 76 }, "evidence": [ { "id": "Q5ZMM5", "url": "https://omabrowser.org/oma/group/Q5ZMM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of stem cell population maintenance", "id": "GO:1902455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902455", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMM5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": 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"taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMR9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XPO4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9", "locus": { "chromosome": "1", "start_pos": 178654563, "end_pos": 178586723, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005482", "url": "https://www.ensembl.org/id/ENSGALG00010005482" } ] } } ], "crossref": [ { "id": "Q5ZMR9", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "428081", "url": "https://www.ncbi.nlm.nih.gov/gene/428081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428081", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMR9", "url": "https://www.orthodb.org/?gene=Q5ZMR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12596:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12596:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMR9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMR9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZMR9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMR9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAAAAAAGGAPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKTSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRIFQEDDLRQIFMLTVEVLQEFRRRENLNAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVMLKPTESWRETLLDSRVMELFFTVHRKIREDTDMAQDSLQCLAQLASLHGSVFPDEGSQVDYLAHFIEGLLNTISGIEIEDSEAVGISSIISNLITVFPRNILTAIPNELFSSFVNCLAHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFCDQLASVGMLGRIAAEHCIPLLTSLLEDRVTRLHGQLQRHQQQLLASPASGSIDNKVLDDLYEDIHWLILVTGYLLANDTQGETPLIPPEVMEYSIKHSTEVDINTTLQILGSPGEKASSIPGYNRTDSVIRLLSAILRVSEVESRAIRANLTHLLSPQMGKDIVWFLKRWAKTYLLADEKLYDQISLPFSTAFGADTEGSQWIVGYLLEKVISNLAVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFARRSPPLHYLSSSVQRTLMKALVLGGFAHMDTEMKQQYWTEVLQPLQQRFLNVINQENFQQICQEEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGEAKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEDQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQATNRTVSAADVVLYGVNLVLPLMSQDLLKFPSLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMSSMSSEVCQLCLEAVTPLAEQCAKAQETDSALFLATRHFLKMVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSTQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "length": 1154, "header": "sp|Q5ZMR9-1|XPO4_CHICK Isoform 1 of Exportin-4 OS=Gallus gallus OX=9031 GN=XPO4 PE=2 SV=1 CANONICAL=Q5ZMR9-1" }, "isoforms": [ { "isoform_ac": "Q5ZMR9-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9/entry#Q5ZMR9-1", "sequence": { "sequence": "MMAAAAAAGGAPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKTSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRIFQEDDLRQIFMLTVEVLQEFRRRENLNAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVMLKPTESWRETLLDSRVMELFFTVHRKIREDTDMAQDSLQCLAQLASLHGSVFPDEGSQVDYLAHFIEGLLNTISGIEIEDSEAVGISSIISNLITVFPRNILTAIPNELFSSFVNCLAHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFCDQLASVGMLGRIAAEHCIPLLTSLLEDRVTRLHGQLQRHQQQLLASPASGSIDNKVLDDLYEDIHWLILVTGYLLANDTQGETPLIPPEVMEYSIKHSTEVDINTTLQILGSPGEKASSIPGYNRTDSVIRLLSAILRVSEVESRAIRANLTHLLSPQMGKDIVWFLKRWAKTYLLADEKLYDQISLPFSTAFGADTEGSQWIVGYLLEKVISNLAVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFARRSPPLHYLSSSVQRTLMKALVLGGFAHMDTEMKQQYWTEVLQPLQQRFLNVINQENFQQICQEEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGEAKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEDQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQATNRTVSAADVVLYGVNLVLPLMSQDLLKFPSLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMSSMSSEVCQLCLEAVTPLAEQCAKAQETDSALFLATRHFLKMVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSTQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "length": 1154, "header": "sp|Q5ZMR9-1|XPO4_CHICK Isoform 1 of Exportin-4 OS=Gallus gallus OX=9031 GN=XPO4 PE=2 SV=1 CANONICAL=Q5ZMR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMR9", "url": "https://www.uniprot.org/uniprotkb/Q5ZMR9" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:428081", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428081", "resource": 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "Q5ZMS1", "uniprot_id": "TAF8_CHICK", "mass": { "chemical_mass": 27511.0, "monoisotopic_mass": 27511.0 }, "refseq": { "ac": "NP_001026094", "name": "transcription initiation factor TFIID subunit 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" }, "gene_names": [ { "name": "TAF8", "type": "recommended", "evidence": [ { "id": "Q5ZMS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ] }, { "name": "RCJMB04_1f12", "type": "synonym", "evidence": [ { "id": "Q5ZMS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ] }, { "name": "TAF8", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] }, { "name": "TBN", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] } ], "protein_names": [ { "name": "Transcription initiation factor TFIID subunit 8", "type": "recommended", "evidence": [ { "id": "Q5ZMS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1/entry#names_and_taxonomy" } ] }, { "name": "TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] }, { "name": "TBP-associated factor 8", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" }, { "id": "Q5ZMS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1/entry#names_and_taxonomy" } ] }, { "name": "taube nuss homolog", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] }, { "name": "transcription initiation factor TFIID subunit 8", "type": "synonym", "evidence": [ { "id": "NP_001026094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719313.1, SRR13267654.232209.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000356.1. On Aug 8, 2005 this sequence version replaced XP_418049.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094" } ] }, { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs). Mediates both basal and activator-dependent transcription.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1#function" }, { "database": "UniProtKB", "id": "Q7Z7C8", "url": "https://www.uniprot.org/uniprotkb/Q7Z7C8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TAF8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1", "locus": { "chromosome": "26", "start_pos": 5117707, "end_pos": 5110062, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026671", "url": "https://www.ensembl.org/id/ENSGALG00010026671" } ] } } ], "crossref": [ { "id": "Q5ZMS1", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003498", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003498", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08049", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08049", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419929", "url": "https://www.ncbi.nlm.nih.gov/gene/419929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419929", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAHNYCE", "url": "https://omabrowser.org/oma/group/SAHNYCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMS1", "url": "https://www.orthodb.org/?gene=Q5ZMS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46469:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46469:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMS1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMS1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMS1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 244, "header": "sp|Q5ZMS1-1|TAF8_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=2 SV=1 CANONICAL=Q5ZMS1-1" }, "isoforms": [ { "isoform_ac": "Q5ZMS1-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1/entry#Q5ZMS1-1", "sequence": { "sequence": "MLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 244, "header": "sp|Q5ZMS1-1|TAF8_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=2 SV=1 CANONICAL=Q5ZMS1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:419929", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419929", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A7MAZ4-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADAAATAGAAGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEMQQMEETDSSEQDEQTDTENLPLHISPDDSGAEKENTSVLQQNPSLSGSRNGEESIIDNPYLRPVKKPKIRRKKSLS", "length": 310 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZY89-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTELFYKAGPQAPPFATSPPHNYKSRRALRSRTLRESKMADTATGPGGSGTRPGNKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQDEQTDTENIALHISTDESGAEKENTSVLQQNSSLSGSRNGEESTIDNPYLRPVKKPKIRRKKLTRKRVLESLTISFHSPSCRSRERNQPAGAALSWTLPTLETRARYFPSWCSWFSPLQFACVIVPSLSEVVLFNCEQTIYVFSTELERQKKI", "length": 435 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HR49-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADTAAGPGGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQDEQTDTENIALHISTGDSGAEKENASVLQQNSSLSGSRNGEENVIDNPYLRPVKKPKIRRKKSLS", "length": 308 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6P0T2-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "taf8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADSVMMGSGSLNSGSRSGSSKTCTSPTENYQLARRRTLQVVVSALLTECGFDSAEKAVVETLTEMMQSYITEVGRCAKANCEHTARSTPTLSDVVITLVEMGFNVDTLPVYAKRSQRMVITAPPITNAPVVPKSLTAGQKRTHPAHIPSHFPDFPDPHTYIRTPTFREPVSDYQVVREKAASQRRDVERALTRFMAKTGETQSLFKDDISAFPLIAAKPSPIPYLSALLPSELELQSLEETDSSEQDDQMDNDNNTSHIMQDDSGADKENEVLPPGGVVPSGKANEENMIDNPYLRPVKKPKVRRKK", "length": 308 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z7C8-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADAAATAGAGGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEMQQMEETDSSEQDEQTDTENLALHISMEDSGAEKENTSVLQQNPSLSGSRNGEENIIDNPYLRPVKKPKIRRKKSLS", "length": 310 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQH4-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTAAGPGGSGTRPGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQILREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQEEQTDTENNALHISTDDSGAEKESASVLQQSSSLSGSRNGEESVIDNPYLRPVKKPKIRRKKSLS", "length": 308 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWY6-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKVEAVTVSNVDPYRRILNKVVSQLLLDKGAGQASNHSLETLTQMLQALIWEIGNSAHNYCELSGRTMPTVGDVSLALINMGISISNLDPYMRKETHVPIPLPPQQTQQRPLSLLQAGIKAPHPHYVPSYFPPMPDPHAYIRTPTHKQPVTEYEAIREKAACQKRDIEKALTKFLCKTTETNNLFPTEDNMFPLIACKPAFPPYAAALNPTDQVFDFEELEYHYLVANRTEDEPSKDDGEEGDSENEEMDGDKSKEEKPELDIKPNSNTNKAILENPNIDNPYLRAATLPKRSKNCPTPGTMPSRSLATTAPTIRTPSTLEITKTNL", "length": 328 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "R4GIW1-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRIALYGSKMADTAPGGSGTRSGSKHTTTPADNYYLARRRTLQVVVSSLLTEAGFESAEKAAVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 312 }, "evidence": [ { "id": "Q5ZMS1", "url": "https://omabrowser.org/oma/group/Q5ZMS1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMS1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMS1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMS1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZMS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS1" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear localization signal", "eco_id": "ECO_0000255", "start_pos": 231, "end_pos": 244, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMS4-1", "uniprot_ac": "Q5ZMS4", "uniprot_id": "NCOA7_CHICK", "mass": { "chemical_mass": 102062.0, "monoisotopic_mass": 102062.0 }, "refseq": { "ac": "NP_001012896", "name": "nuclear receptor coactivator 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012896" }, "gene_names": [ { "name": "NCOA7", "type": "recommended", "evidence": [ { "id": "Q5ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4" } ] }, { "name": "NCOA7", "type": "synonym", "evidence": [ { "id": "NP_001012896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012896" } ] }, { "name": "RCJMB04_1f5", "type": "synonym", "evidence": [ { "id": "Q5ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4" } ] } ], "protein_names": [ { "name": "Nuclear receptor coactivator 7", "type": "recommended", "evidence": [ { "id": "Q5ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor coactivator 7", "type": "synonym", "evidence": [ { "id": "NP_001012896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012896" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.56400.1, SRR13267649.42607.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Sep 23, 2021 this sequence version replaced NP_001012896.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001012896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012896" } ] }, { "annotation": "Transcriptional coactivator which enhances the transcriptional activities of several nuclear receptors (By similarity). Inhibits the activity of the vacuolar-type ATPase (V-ATPase) by inducing disassembly of the V-ATPase complex (By similarity). Protects the Golgi apparatus lumen from excess acidification by inhibiting V-ATPase ATP hydrolytic activity, maintaining optimal conditions for glycosylation enzymes (By similarity). Required to stabilize V-ATPase V1 subunits ATP6V1B2 and ATP6V1A at membrane sites (By similarity). Involved in protection against oxidative damage (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4#function" }, { "database": "UniProtKB", "id": "Q6DFV7", "url": "https://www.uniprot.org/uniprotkb/Q6DFV7#function" }, { "database": "UniProtKB", "id": "Q8NI08", "url": "https://www.uniprot.org/uniprotkb/Q8NI08#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCOA7", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4", "locus": { "chromosome": "3", "start_pos": 59414066, "end_pos": 59499575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004087", "url": "https://www.ensembl.org/id/ENSGALG00010004087" } ] } } ], "crossref": [ { "id": "Q5ZMS4", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421717", "url": "https://www.ncbi.nlm.nih.gov/gene/421717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421717", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMS4", "url": "https://www.orthodb.org/?gene=Q5ZMS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMS4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMS4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMS4", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMS4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKEEKKERRQGYFARLKKKRQAKQNTETVSANSPGSPVSKTPAEKDDESKVILEQISSSGDNCKFAGEKETVPEKEKRKKKYNQLKDIRRTELKRYYSTDDNQNKTNEKKEKKMVSQKPHGTIEYTAGNQDTINSIALKFNITPNKLVELNKLFTHTIVPGQILFVPETSVARLPSFSPGAPISPSSSDAEYDKLPDADLARKAFKPVERVLSSTSEEDEPVVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDIPKDLCPLYRPGEWEDLSSEKDINPFSKFKSLSKEKRQQNGDSPNVPGAKQINPSDKEKSADFEVLQSSESTGSIKSKSLEFYNNITATEHLEKFAADPHVKEPSEEKNVSDIRTKEDSLSGGGDDFIDLEKVPSPMDRGLDRKISLMEGLLADPRELGRTKQQVTKPTTEVQEHFTVDSLEKKDSVEPKADLDLELCEKQDVIPEVNKCVSSPTGKVETALDTKKELEKDKLIEFYLNKDGSGSQSSEDLHKAEIQKGENNKAIGIDLTLSCSKSQADEVHTVKSMELDSCCVGRKAASLESSAAAAEEKDLKESLDSSLVPAVDKTCQETQLDNQSEVRLWLLQKIQVPIEDMLPSKEEKSKTPPMFLCIKVGKPMRKSFVSQSTTVSQQYSKKIKQPEYWFAVPREIITVEEAKRRKSVCSYYGEEDDDDALPVLKHHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENTYFINGDMTSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIIQDVEVWTFE", "length": 907, "header": "sp|Q5ZMS4-1|NCOA7_CHICK Isoform 1 of Nuclear receptor coactivator 7 OS=Gallus gallus OX=9031 GN=NCOA7 PE=2 SV=1 CANONICAL=Q5ZMS4-1" }, "isoforms": [ { "isoform_ac": "Q5ZMS4-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS4/entry#Q5ZMS4-1", "sequence": { "sequence": "METKEEKKERRQGYFARLKKKRQAKQNTETVSANSPGSPVSKTPAEKDDESKVILEQISSSGDNCKFAGEKETVPEKEKRKKKYNQLKDIRRTELKRYYSTDDNQNKTNEKKEKKMVSQKPHGTIEYTAGNQDTINSIALKFNITPNKLVELNKLFTHTIVPGQILFVPETSVARLPSFSPGAPISPSSSDAEYDKLPDADLARKAFKPVERVLSSTSEEDEPVVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDIPKDLCPLYRPGEWEDLSSEKDINPFSKFKSLSKEKRQQNGDSPNVPGAKQINPSDKEKSADFEVLQSSESTGSIKSKSLEFYNNITATEHLEKFAADPHVKEPSEEKNVSDIRTKEDSLSGGGDDFIDLEKVPSPMDRGLDRKISLMEGLLADPRELGRTKQQVTKPTTEVQEHFTVDSLEKKDSVEPKADLDLELCEKQDVIPEVNKCVSSPTGKVETALDTKKELEKDKLIEFYLNKDGSGSQSSEDLHKAEIQKGENNKAIGIDLTLSCSKSQADEVHTVKSMELDSCCVGRKAASLESSAAAAEEKDLKESLDSSLVPAVDKTCQETQLDNQSEVRLWLLQKIQVPIEDMLPSKEEKSKTPPMFLCIKVGKPMRKSFVSQSTTVSQQYSKKIKQPEYWFAVPREIITVEEAKRRKSVCSYYGEEDDDDALPVLKHHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENTYFINGDMTSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIIQDVEVWTFE", "length": 907, "header": "sp|Q5ZMS4-1|NCOA7_CHICK Isoform 1 of Nuclear receptor 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6" } ] }, { "name": "RCJMB04_1e24", "type": "synonym", "evidence": [ { "id": "Q5ZMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6" } ] } ], "protein_names": [ { "name": "Tudor domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "Q5ZMS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6#function" }, { "database": "UniProtKB", "id": "Q9H7E2", "url": "https://www.uniprot.org/uniprotkb/Q9H7E2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TDRD3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6", "locus": { "chromosome": "1", "start_pos": 162086382, "end_pos": 162190733, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002381", "url": "https://www.ensembl.org/id/ENSGALG00010002381" } ] } } ], "crossref": [ { "id": "Q5ZMS6", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14282", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14282", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20413", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20413", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418823", "url": "https://www.ncbi.nlm.nih.gov/gene/418823", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418823", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418823", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMS6", "url": "https://www.orthodb.org/?gene=Q5ZMS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13681", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13681", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13681:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13681:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMS6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMS6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZMS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMS6-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRARAALSESGWYLSDEGIETCINSSEKVNTNDIILVALNTDLRTIGKKFLPSDINGGKVEKLEGPCVLQIQKIRNVSAPKDNEESQAAPRMLRLQMTDGHTSCTAIEYNSMSKISLNTPPGTKIKLSGIIEVRNGFLLLDDSNTAVLGGEVEHLIEKWELQRSLAKHSRSNIGTEGGPPPFLPFGQKCASHMQVDSRELDRRKTLQMTNTAKPVTDNDEFEKQRTAAIAEVAKSKETKTFGGGGGSSRSNLTVSAGGNRNRELFQKEKITKPEGKNEGVYRELVDEKALKHITEMGFSKEAARQALMDNSNNLEAALNFLLSSNKQKPLQGPPPRGKGKGRGRIRPEDEEELGNARPSAPSTLFDFLESKMGTLTVEEPKLQFQPPHQVQPKVMNTEQNGIKENHSRHISRNDMRQPRNEKPPRFQRDIQNSRQALESGGLPRNRGPERHNSLEHWTDEKIKSDRHYPRNDRPKDLGYPIAAHQSDISFKKRDNNMQNRIGKGVSFTEFKENSAAQDATDNNNQKRGKRENQIHNSENFCDRKARTISNETFMVKSEQHFGVNNDYQNPCRTDNFNSIPNGDTEHHQKGRRVGPIKLSGPTVIPSYDDKILYYNTGPKRRSGPIKPEKIMEPSIHAEYGKTWRPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFSDYGNYEEVLLSNIRPIHADTWEDEEETYEQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN", "length": 741, "header": "sp|Q5ZMS6-1|TDRD3_CHICK Isoform 1 of Tudor domain-containing protein 3 OS=Gallus gallus OX=9031 GN=TDRD3 PE=2 SV=1 CANONICAL=Q5ZMS6-1" }, "isoforms": [ { "isoform_ac": "Q5ZMS6-1", "url": 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"locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZMS6" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:418823", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418823", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": 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] }, { "uniprot_canonical_ac": "Q5ZMV2-1", "uniprot_ac": "Q5ZMV2", "uniprot_id": "SAS6_CHICK", "mass": { "chemical_mass": 73621.0, "monoisotopic_mass": 73621.0 }, "refseq": {}, "gene_names": [ { "name": "SASS6", "type": "recommended", "evidence": [ { "id": "Q5ZMV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ] }, { "name": "RCJMB04_1b15", "type": "synonym", "evidence": [ { "id": "Q5ZMV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ] }, { "name": "SAS6", "type": "synonym", "evidence": [ { "id": "Q5ZMV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ] } ], "protein_names": [ { "name": "Spindle assembly abnormal protein 6 homolog", "type": "recommended", "evidence": [ { "id": "Q5ZMV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2#function" }, { "database": "UniProtKB", "id": "Q6UVJ0", "url": "https://www.uniprot.org/uniprotkb/Q6UVJ0#function" }, { "database": "UniProtKB", "id": "Q7ZVT3", "url": "https://www.uniprot.org/uniprotkb/Q7ZVT3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SASS6", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2", "locus": { "chromosome": "8", "start_pos": 11683063, "end_pos": 11670612, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023890", "url": "https://www.ensembl.org/id/ENSGALG00010023890" } ] } } ], "crossref": [ { "id": "Q5ZMV2", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10142", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10142", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424471", "url": "https://www.ncbi.nlm.nih.gov/gene/424471", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424471", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424471", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMV2", "url": "https://www.orthodb.org/?gene=Q5ZMV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44281:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44281:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMV2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMV2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMV2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQSLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQEDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKENGDNLGLESKYFKKKEDSIPLRGLSQNTLNSENLKPYLPKVQPSLPAAVTTTSAYFPG", "length": 640, "header": "sp|Q5ZMV2-1|SAS6_CHICK Isoform 1 of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=2 SV=1 CANONICAL=Q5ZMV2-1" }, "isoforms": [ { "isoform_ac": "Q5ZMV2-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2/entry#Q5ZMV2-1", "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQSLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQEDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKENGDNLGLESKYFKKKEDSIPLRGLSQNTLNSENLKPYLPKVQPSLPAAVTTTSAYFPG", "length": 640, "header": "sp|Q5ZMV2-1|SAS6_CHICK Isoform 1 of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=2 SV=1 CANONICAL=Q5ZMV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:424471", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424471", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "pmid": "" }, { "name": "deuterosome", "id": "GO:0098536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098536", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMV2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 640, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMV2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMV2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMV8-1", "uniprot_ac": "Q5ZMV8", "uniprot_id": "RPGP2_CHICK", "mass": { "chemical_mass": 80792.0, "monoisotopic_mass": 80792.0 }, "refseq": { "ac": "NP_001026649", "name": "rap1 GTPase-activating protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" }, "gene_names": [ { "name": "RAP1GAP2", "type": "recommended", "evidence": [ { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ] }, { "name": "GARNL4", "type": "synonym", "evidence": [ { "id": "NP_001026649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" }, { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ] }, { "name": "RAP1GAP2", "type": "synonym", "evidence": [ { "id": "NP_001026649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" } ] }, { "name": "RCJMB04_1a20", "type": "synonym", "evidence": [ { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ] } ], "protein_names": [ { "name": "Rap1 GTPase-activating protein 2", "type": "recommended", "evidence": [ { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8/entry#names_and_taxonomy" } ] }, { "name": "GTPase activating Rap/RanGAP domain-like 4", "type": "synonym", "evidence": [ { "id": "NP_001026649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" } ] }, { "name": "GTPase-activating Rap/Ran-GAP domain-like protein 4", "type": "synonym", "evidence": [ { "id": "NP_001026649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" }, { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8/entry#names_and_taxonomy" } ] }, { "name": "Rap1GAP2", "type": "synonym", "evidence": [ { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8/entry#names_and_taxonomy" } ] }, { "name": "rap1 GTPase-activating protein 2", "type": "synonym", "evidence": [ { "id": "NP_001026649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719276.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1, AJ719276.1, AJ741027.1, AJ741039.1 and AJ741038.1. On Aug 14, 2005 this sequence version replaced NP_001026649.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649" } ] }, { "annotation": "GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAP1GAP2", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8", "locus": { "chromosome": "19", "start_pos": 10054146, "end_pos": 10002761, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029255", "url": "https://www.ensembl.org/id/ENSGALG00010029255" } ] } } ], "crossref": [ { "id": "Q5ZMV8", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "427841", "url": "https://www.ncbi.nlm.nih.gov/gene/427841", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427841", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427841", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5ZMV8", "url": "https://www.orthodb.org/?gene=Q5ZMV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMV8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMV8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001026649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMV8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQRKRSVSFGGYGWIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTDIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 730, "header": "sp|Q5ZMV8-1|RPGP2_CHICK Isoform 1 of Rap1 GTPase-activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=2 SV=2 CANONICAL=Q5ZMV8-1" }, "isoforms": [ { "isoform_ac": "Q5ZMV8-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8/entry#Q5ZMV8-1", "sequence": { "sequence": "MFQRKRSVSFGGYGWIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTDIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 730, "header": "sp|Q5ZMV8-1|RPGP2_CHICK Isoform 1 of Rap1 GTPase-activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=2 SV=2 CANONICAL=Q5ZMV8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:427841", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427841", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMV8", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMV8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 730, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMV8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMV8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZMV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMV8" }, { "id": "PRU00165", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00165" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000255", "start_pos": 247, "end_pos": 463, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 633, "end_pos": 635 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5ZMW3-1", "uniprot_ac": "Q5ZMW3", "uniprot_id": "API5_CHICK", "mass": { "chemical_mass": 58609.0, "monoisotopic_mass": 58609.0 }, "refseq": { "ac": "NP_001006474", "name": "apoptosis inhibitor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474" }, "gene_names": [ { "name": "API5", "type": "recommended", "evidence": [ { "id": "Q5ZMW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ] }, { "name": "API5", "type": "synonym", "evidence": [ { "id": "NP_001006474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474" } ] }, { "name": "RCJMB04_1a12", "type": "synonym", "evidence": [ { "id": "Q5ZMW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ] } ], "protein_names": [ { "name": "Apoptosis inhibitor 5", "type": "recommended", "evidence": [ { "id": "Q5ZMW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3/entry#names_and_taxonomy" } ] }, { "name": "API-5", "type": "synonym", "evidence": [ { "id": "NP_001006474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474" }, { "id": "Q5ZMW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3/entry#names_and_taxonomy" } ] }, { "name": "apoptosis inhibitor 5", "type": "synonym", "evidence": [ { "id": "NP_001006474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719271.1, HAEK01050293.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000214.1. On Jan 13, 2005 this sequence version replaced XP_421094.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474" } ] }, { "annotation": "Antiapoptotic factor that may have a role in protein assembly.", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "API5", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3", "locus": { "chromosome": "5", "start_pos": 20958277, "end_pos": 20942079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021048", "url": "https://www.ensembl.org/id/ENSGALG00010021048" } ] } } ], "crossref": [ { "id": "Q5ZMW3", "url": "https://alphafold.ebi.ac.uk/entry/Q5ZMW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037968", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037968", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423168", "url": "https://www.ncbi.nlm.nih.gov/gene/423168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423168", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCIKFLA", "url": "https://omabrowser.org/oma/group/RCIKFLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5ZMW3", "url": "https://www.orthodb.org/?gene=Q5ZMW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5ZMW3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5ZMW3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5ZMW3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 523, "header": "sp|Q5ZMW3-1|API5_CHICK Isoform 1 of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=2 SV=1 CANONICAL=Q5ZMW3-1" }, "isoforms": [ { "isoform_ac": "Q5ZMW3-1", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3/entry#Q5ZMW3-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 523, "header": "sp|Q5ZMW3-1|API5_CHICK Isoform 1 of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=2 SV=1 CANONICAL=Q5ZMW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] } ], "pathway": [ { "id": "gga:423168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423168", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G9F8-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENASNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRANEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1WC49-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRTSEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35841-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQAFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRTSEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLSNFNYERSLQGK", "length": 504 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54CL0-1", "protein_name": "Apoptosis inhibitor 5 homolog", "gene_name": "api5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METTTTTTTAAATKGTNDAMETSSSTTATPTTATVVPQVVRNDEYINTFYDIANKLDTNPSFPDDDKLFSKIIELSSKTKQTKKLSPQFISKYFKRFPTLQEKAIDCLIDLFDSSDEDVIMRVNALKAIPTICRDNPDHIAKLVDILSQLLNTDSKVEAEHTKNSLIELYKLNSVTTLNSFLTFLESEESSMEDQPASSTLLSFLKESIIPLVRTEYSKSSIETQTFFRVRILKLIAKCTSTTELDLLFQLLECFTQYKVQETITDLETNVLPVIESQSLDTIRKKLINFTKILLFKSKKPHTEINSNKLFDLYLNKIFPKVNELDETNKTELVSVFSQVTPHMTQEISMQFLEPVYNLFKATVPSKTTTPVADVDLQFTIVEALLFALSSIGSKSTSSLCKLCGFKLVTGQPSDMNADPVKYEDFLGRHRFLDEKCRETLGKAKKAIPNLGNPKDKAQLKLAQKTLLSTQNILTIMQNLLKSPPVTNINNLVISSTIFKGKQNLIHNVSPVFKPQQHQHQHQQQQVQQKQYQKYQAQQQQQQNIPIQRNQQQQQQQKSNRYQPYVTPGRRHQDLDKPKQDGVEVHYYSEKHNKPSSFKGRGPKSY", "length": 606 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9BZZ5-4", "protein_name": "Apoptosis inhibitor 5", "gene_name": "API5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRASEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V431-1", "protein_name": "Apoptosis inhibitor 5 homolog", "gene_name": "cass", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDNIERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAIDAQFDLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLDTKSSIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHLCMTILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKSTAFVAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYMPLPKLSDEDLGDTPPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLARGTQGYIKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSWIVPKNNKLGKRHAPITFGEKAAANGKDKDQEPEKKSRPSNDQKFYSPPSGKYSNKVNQSYGNNNRTRQRGGGGGGGSGGGYRNRRFNKY", "length": 536 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "R4GDP5-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "api5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATVEELYRNYGILADAKEDLSTHKDAYQVILDGVKGGAKEKRLAAQFIPKFFSSFPELADAAINAQLDLCEDEDVSIRRQAIKELPRFASGENLPRVADILTQLLQTDDSAEFNQVNTALISIFKIDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTMPEDIMTKEVEDYIFVETKKVLEDVTGEEFVLLMRILSGLKSMQTVSGRQQLVELVVEQAFLEQALNPADTDSVDRLLQCTRQALPLFSKNVHSTRFVTYFCEFVLPNLSQLTSPVAELDIQLEVLKLLAEMSPYCGDMDKLEVNLNMLFEKLLEFMPLPPEEENGENAANEEPKLQFSYVECLLFSFHQLGKKLPDFLIDKVSAEKLKDFKIRLQYFARGLQVYIRQLRVALQGKTGDALKTDENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQKTEAAAAIGQKRRSGEDIGATATTKKHPTNLPRRDARQIYNPPSGKYSASIGNFSYEQRGGFRGGRGRGFGGRGNRSRGRIY", "length": 529 }, "evidence": [ { "id": "Q5ZMW3", "url": "https://omabrowser.org/oma/group/Q5ZMW3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q5ZMW3", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5ZMW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 523, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5ZMW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5ZMW3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5ZMW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZMW3" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear localization signal", "eco_id": "ECO_0000250", "start_pos": 454, "end_pos": 475, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 516, "end_pos": 518 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q6GVH4-1", "uniprot_ac": "Q6GVH4", "uniprot_id": "GGNB2_CHICK", "mass": { "chemical_mass": 79222.0, "monoisotopic_mass": 79222.0 }, "refseq": { "ac": "NP_001001899", "name": "gametogenetin-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" }, "gene_names": [ { "name": "GGNBP2", "type": "recommended", "evidence": [ { "id": "Q6GVH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ] }, { "name": "GGNBP2", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" } ] }, { "name": "RCJMB04_15h5", "type": "synonym", "evidence": [ { "id": "Q6GVH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ] }, { "name": "ZFP403", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" } ] }, { "name": "ZNF403", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" }, { "id": "Q6GVH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ] } ], "protein_names": [ { "name": "Gametogenetin-binding protein 2", "type": "recommended", "evidence": [ { "id": "Q6GVH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4/entry#names_and_taxonomy" } ] }, { "name": "Protein ZNF403", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" }, { "id": "Q6GVH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4/entry#names_and_taxonomy" } ] }, { "name": "gametogenetin-binding protein 2", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" } ] }, { "name": "zinc finger protein 403", "type": "synonym", "evidence": [ { "id": "NP_001001899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY633743.1, SRR13267648.4898.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1. On Jan 18, 2005 this sequence version replaced XP_415897.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899" } ] }, { "annotation": "May be involved in spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GGNBP2", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4", "locus": { "chromosome": "19", "start_pos": 8650168, "end_pos": 8627096, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029925", "url": "https://www.ensembl.org/id/ENSGALG00010029925" } ] } } ], "crossref": [ { "id": "Q6GVH4", "url": "https://alphafold.ebi.ac.uk/entry/Q6GVH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005397", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005397", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425053", "url": "https://www.ncbi.nlm.nih.gov/gene/425053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425053", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q6GVH4", "url": "https://www.orthodb.org/?gene=Q6GVH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13601:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:Q6GVH4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q6GVH4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001001899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6GVH4-1", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6GVH4-2", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 698, "header": "sp|Q6GVH4-1|GGNB2_CHICK Isoform 1 of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=2 SV=1 CANONICAL=Q6GVH4-1" }, "isoforms": [ { "isoform_ac": "Q6GVH4-1", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4/entry#Q6GVH4-1", "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 698, "header": "sp|Q6GVH4-1|GGNB2_CHICK Isoform 1 of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=2 SV=1 CANONICAL=Q6GVH4-1" }, "locus": {} }, { "isoform_ac": "Q6GVH4-2", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4/entry#Q6GVH4-2", "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 700, "header": "sp|Q6GVH4-2|GGNB2_CHICK Isoform 2 of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=2 SV=1 CANONICAL=Q6GVH4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.", "journal": "FEBS Lett.", "date": "2005", "authors": "Zhang J, Wang Y, Zhou Y, Cao Z, Huang P, Lu B", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "reference": [ { "type": "PubMed", "id": "15642376", "url": "https://glygen.org/publication/PubMed/15642376" } ] } ], "pathway": [ { "id": "gga:425053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425053", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6GVH4", "url": "https://www.uniprot.org/uniprotkb/Q6GVH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q6GVH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 698, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q6GVH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q6GVH4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 434, "end_pos": 436 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 656, "end_pos": 658 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q6K1L7-1", "uniprot_ac": "Q6K1L7", "uniprot_id": "EIF1A_CHICK", "mass": { "chemical_mass": 21235.0, "monoisotopic_mass": 21235.0 }, "refseq": { "ac": "NP_001001612", "name": "probable RNA-binding protein EIF1AD", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" }, "gene_names": [ { "name": "eif1ad", "type": "recommended", "evidence": [ { "id": "Q6K1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7" } ] }, { "name": "EIF1AD", "type": "synonym", "evidence": [ { "id": "NP_001001612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] } ], "protein_names": [ { "name": "Probable RNA-binding protein EIF1AD", "type": "recommended", "evidence": [ { "id": "Q6K1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 1A domain-containing protein", "type": "synonym", "evidence": [ { "id": "Q6K1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7/entry#names_and_taxonomy" } ] }, { "name": "Protein Obelix", "type": "synonym", "evidence": [ { "id": "Q6K1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 1A domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001001612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] }, { "name": "obelix", "type": "synonym", "evidence": [ { "id": "NP_001001612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] }, { "name": "probable RNA-binding protein EIF1AD", "type": "synonym", "evidence": [ { "id": "NP_001001612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] }, { "name": "protein Obelix", "type": "synonym", "evidence": [ { "id": "NP_001001612", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY103477.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY103477.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612" } ] }, { "annotation": "May play a role into cellular response to oxidative stress. May decrease cell proliferation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q6K1L7", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q6K1L7", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "eif1ad", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7", "locus": {} } ], "crossref": [ { "id": "Q6K1L7", "url": "https://alphafold.ebi.ac.uk/entry/Q6K1L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414740", "url": "https://www.ncbi.nlm.nih.gov/gene/414740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21641", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21641", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21641:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21641:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q6K1L7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q6K1L7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001001612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q6K1L7", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6K1L7-1", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRATKRKHVTREVLEEHVVPAPQQRIVRVLGSPGNNLHEVETADGSRFLASMPPRFRHHVWIKRGDFLLVDPIEEGAKVKAEMALVLLRPHVRFLQRQGLWPTAFAASPDRTPQESDGDSELFVNTNRATIETDTEEEEEDGGDTESSEEEEEDREEPLEDRPEDRPEDCADVGSAAQRRSTIETGT", "length": 188, "header": "sp|Q6K1L7-1|EIF1A_CHICK Isoform 1 of Probable RNA-binding protein EIF1AD OS=Gallus gallus OX=9031 GN=eif1ad PE=2 SV=1 CANONICAL=Q6K1L7-1" }, "isoforms": [ { "isoform_ac": "Q6K1L7-1", "url": "https://www.uniprot.org/uniprotkb/Q6K1L7/entry#Q6K1L7-1", "sequence": { "sequence": "MSRATKRKHVTREVLEEHVVPAPQQRIVRVLGSPGNNLHEVETADGSRFLASMPPRFRHHVWIKRGDFLLVDPIEEGAKVKAEMALVLLRPHVRFLQRQGLWPTAFAASPDRTPQESDGDSELFVNTNRATIETDTEEEEEDGGDTESSEEEEEDREEPLEDRPEDRPEDCADVGSAAQRRSTIETGT", "length": 188, "header": "sp|Q6K1L7-1|EIF1A_CHICK Isoform 1 of Probable RNA-binding protein EIF1AD OS=Gallus gallus OX=9031 GN=eif1ad PE=2 SV=1 CANONICAL=Q6K1L7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Distinct steps of neural induction revealed by Asterix, Obelix and TrkC, genes induced by different signals from the organizer.", "journal": "PLoS ONE", "date": "2011", "authors": "Pinho Sonia, Simonsson Pamela R, Trevers Katherine E, Stower Matthew J, Sherlock William T, Khan Mohsin, Streit Andrea, Sheng Guojun, 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040551602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551602" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNDP1", "url": "https://www.uniprot.org/uniprotkb/F1P464", "locus": { "chromosome": "2", "start_pos": 91437571, "end_pos": 91455225, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001231", "url": "https://www.ensembl.org/id/ENSGALG00010001231" } ] } } ], "crossref": [ { "id": "F1P464", "url": "https://alphafold.ebi.ac.uk/entry/F1P464", "database": "AlphaFoldDB", 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"MSLSSLSALRTEIFHYIDAHQSDFIENLKEWVAVESDSVQPDLRKEVIRMMSLAAARLAALGATVNSVSLGSQQLLNGQHLPLPPVILGELGKDPQNLTICFYGHVDVQPAKKEDGWKTDPFTLTEINGNLYGRGATDNKGPVLAWINAVGTFRALKRAMPVNFKFVIEGMEEAGSLGLEKLLEEEKQGFFSDVDYIVISDNLWLSKKKPALIYGTRGNACFCVEVEGGDKDLHSGTFGGIIHEPLTDLIALLDSLVDPTGHIQIPGIYDAVAVLTDEEKKLYESIEYDIEEHKNNSGVKKLLYSTKEEILLHLWRYPSLSIHGIEGAFHEPGIKTVIPAKVIGKFSIRQVPNMDLSDVHQRVVDHLENVFAKRNSPNKLKVSMPLGAQPWVADVNDPLYKAAKRAIKTVFGEDPDFIRDGSTIPIARIFQTITQKRVIMFPIGAADDGEHSQNEKISRFNYIEGTKVFAAFFLEIAKLRGQSHETSNPGTNN", "length": 493, "header": "tr|F1P464-1|F1P464_CHICK Isoform 1 of Carnosine dipeptidase 1 OS=Gallus gallus OX=9031 GN=CNDP1 PE=1 SV=2 CANONICAL=F1P464-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X1P6-1", "url": "https://www.uniprot.org/uniprotkb/F1P464/entry#A0A8V0X1P6-1", "sequence": { "sequence": "MSLSSLSALRTEIFHYIDAHQSDFIENLKEWVAVESDSVQPDLRKEVIRMMSLAAARLAALGATVNSLLNGQHLPLPPVILGELGKDPQNLTICFYGHVDVQPAKKEDGWKTDPFTLTEINGNLYGRGATDNKGPVLAWINAVGTFRALKRAMPVNFKFVIEGMEEAGSLGLEKLLEEEKQGFFSDVDYIVISDNLWLSKKKPALIYGTRGNACFCVEVEGGDKDLHSGTFGGIIHEPLTDLIALLDSLVDPTGHIQIPGIYDAVAVLTDEEKKLYESIEYDIEEHKNNSGVKKLLYSTKEEILLHLWRYPSLSIHGIEGAFHEPGIKTVIPAKVIGKFSIRQVPNMDLSDVHQRVVDHLENVFAKRNSPNKLKVSMPLGAQPWVADVNDPLYKAAKRAIKTVFGEDPDFIRDGSTIPIARIFQTITQKRVIMFPIGAADDGEHSQNEKISRFNYIEGTKVFAAFFLEIAKLRGQSHETSNPGTNN", "length": 486, "header": "tr|A0A8V0X1P6-1|F1P464_CHICK Computationally mapped isoform of Carnosine dipeptidase 1 OS=Gallus gallus OX=9031 GN=CNDP1 PE=1 SV=1 CANONICAL=F1P464-1" }, "locus": { "chromosome": "2", "start_pos": 91450155, "end_pos": 91438634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002848.1", "url": "https://www.ensembl.org/id/ENSGALT00010002848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001398.1", "url": "https://www.ensembl.org/id/ENSGALP00010001398.1" } ] } }, { "isoform_ac": "F1P464-1", "url": "https://www.uniprot.org/uniprotkb/F1P464/entry#F1P464-1", "sequence": { "sequence": "MSLSSLSALRTEIFHYIDAHQSDFIENLKEWVAVESDSVQPDLRKEVIRMMSLAAARLAALGATVNSVSLGSQQLLNGQHLPLPPVILGELGKDPQNLTICFYGHVDVQPAKKEDGWKTDPFTLTEINGNLYGRGATDNKGPVLAWINAVGTFRALKRAMPVNFKFVIEGMEEAGSLGLEKLLEEEKQGFFSDVDYIVISDNLWLSKKKPALIYGTRGNACFCVEVEGGDKDLHSGTFGGIIHEPLTDLIALLDSLVDPTGHIQIPGIYDAVAVLTDEEKKLYESIEYDIEEHKNNSGVKKLLYSTKEEILLHLWRYPSLSIHGIEGAFHEPGIKTVIPAKVIGKFSIRQVPNMDLSDVHQRVVDHLENVFAKRNSPNKLKVSMPLGAQPWVADVNDPLYKAAKRAIKTVFGEDPDFIRDGSTIPIARIFQTITQKRVIMFPIGAADDGEHSQNEKISRFNYIEGTKVFAAFFLEIAKLRGQSHETSNPGTNN", "length": 493, "header": "tr|F1P464-1|F1P464_CHICK Isoform 1 of Carnosine dipeptidase 1 OS=Gallus gallus OX=9031 GN=CNDP1 PE=1 SV=2 CANONICAL=F1P464-1" }, "locus": { "chromosome": "2", "start_pos": 91450155, "end_pos": 91438634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002849.1", "url": "https://www.ensembl.org/id/ENSGALT00010002849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001399.1", "url": "https://www.ensembl.org/id/ENSGALP00010001399.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421012", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P464", "url": "https://www.uniprot.org/uniprotkb/F1P464" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P464-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 493, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P464-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P464" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P464" }, { "id": "PF07687", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07687" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M20 dimerisation", "eco_id": "ECO_0000259", "start_pos": 215, "end_pos": 373, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "F1P464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P464#function" }, { "id": "F1P464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P464" }, { "id": "PIRSR037242-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037242-3" } ], "binding_site_uniprot": 105, "amino_acid": "His", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 105, "end_pos": 105, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0X1P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1P6#function" }, { "id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q90VZ9-1", "uniprot_ac": "Q90VZ9", "uniprot_id": "HXA7_CHICK", "mass": { "chemical_mass": 24953.0, "monoisotopic_mass": 24953.0 }, "refseq": { "ac": "NP_989926", "name": "homeobox protein Hox-A7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" }, "gene_names": [ { "name": "HOXA7", "type": "recommended", "evidence": [ { "id": "Q90VZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ] }, { "name": "HOXA-7", "type": "synonym", "evidence": [ { "id": "NP_989926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" }, { "id": "Q90VZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ] }, { "name": "HOXA7", "type": "synonym", "evidence": [ { "id": "NP_989926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-A7", "type": "recommended", "evidence": [ { "id": "Q90VZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9/entry#names_and_taxonomy" } ] }, { "name": "homeo box A7", "type": "synonym", "evidence": [ { "id": "NP_989926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ] }, { "name": "homeobox protein Hox-A7", "type": "synonym", "evidence": [ { "id": "NP_989926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ] }, { "name": "homeodomain transcription factor HoxA-7", "type": "synonym", "evidence": [ { "id": "NP_989926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267647.18001.1, ERR2365562.110797.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000037.1. On Aug 30, 2004 this sequence version replaced XP_444651.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ] }, { "annotation": "During development, Hox expression boundaries become set along instructional cdx gradients, formed by cdx decay in cells moving away from the primitive streak region", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" }, { "database": "PubMed", "id": "15470633", "url": "https://glygen.org/publication/PubMed/15470633" } ] }, { "annotation": "HOXA7, HOXB3, HOXA3, and HOXB13 expression levels changed during angiogenesis, sugessting these proteins might be involved in the angiogenesis of hMSCs.", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" }, { "database": "PubMed", "id": "17972163", "url": "https://glygen.org/publication/PubMed/17972163" } ] }, { "annotation": "Low expression of HOXA7 RNA is associated with hyperdiploid leukemia.", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" }, { "database": "PubMed", "id": "20672366", "url": "https://glygen.org/publication/PubMed/20672366" } ] }, { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9#function" }, { "database": "UniProtKB", "id": "A0A8V0X3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3P3#function" }, { "database": "UniProtKB", "id": "ARBA00003263", "url": "https://www.uniprot.org/uniprotkb/ARBA00003263#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXA7", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9", "locus": { "chromosome": "2", "start_pos": 32537106, "end_pos": 32542394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001826", "url": "https://www.ensembl.org/id/ENSGALG00010001826" } ] } } ], "crossref": [ { "id": "Q90VZ9", "url": "https://alphafold.ebi.ac.uk/entry/Q90VZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026989", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026989", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395290", "url": "https://www.ncbi.nlm.nih.gov/gene/395290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395290", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395290", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0X3P3", "url": "https://www.orthodb.org/?gene=A0A8V0X3P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q90VZ9", "url": "https://www.orthodb.org/?gene=Q90VZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45659:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45659:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q90VZ9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q90VZ9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X3P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90VZ9-1", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSYYVNALFSKYTAGASLFQNAEPTSCSFASNSQRSGYGPGAGAFASSMPGLYNVNSTIYQSPFSSGYSLGSDAYNLHCSSFDQNIPVLCNDLTKPSCEKAEESNLHNQAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKEESSSTPAPNEPTSAAASVEKVEEDEEEED", "length": 219, "header": "sp|Q90VZ9-1|HXA7_CHICK Isoform 1 of Homeobox protein Hox-A7 OS=Gallus gallus OX=9031 GN=HOXA7 PE=2 SV=1 CANONICAL=Q90VZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X3P3-1", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9/entry#A0A8V0X3P3-1", "sequence": { "sequence": "AHEAAGANSELLRRFVRREAFLTLLLLLFAGWQLKSCEQTKRKRRRPQHTPAKLTASQRFFCRHAQPEIHALSSAVRFDGIDIRAQTSANIPVLCNDLTKPSCEKAEESNLHNQAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKEESSSTPAPNEPTSAAASVEKVEEDEEEED", "length": 222, "header": "tr|A0A8V0X3P3-1|HXA7_CHICK Computationally mapped isoform of Homeobox protein Hox-A7 OS=Gallus gallus OX=9031 GN=HOXA7 PE=2 SV=1 CANONICAL=Q90VZ9-1" }, "locus": { "chromosome": "2", "start_pos": 32542394, "end_pos": 32538657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004159.1", "url": "https://www.ensembl.org/id/ENSGALT00010004159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002456.1", "url": "https://www.ensembl.org/id/ENSGALP00010002456.1" } ] } }, { "isoform_ac": "Q90VZ9-1", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9/entry#Q90VZ9-1", "sequence": { "sequence": "MSSSYYVNALFSKYTAGASLFQNAEPTSCSFASNSQRSGYGPGAGAFASSMPGLYNVNSTIYQSPFSSGYSLGSDAYNLHCSSFDQNIPVLCNDLTKPSCEKAEESNLHNQAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKEESSSTPAPNEPTSAAASVEKVEEDEEEED", "length": 219, "header": "sp|Q90VZ9-1|HXA7_CHICK Isoform 1 of Homeobox protein Hox-A7 OS=Gallus gallus OX=9031 GN=HOXA7 PE=2 SV=1 CANONICAL=Q90VZ9-1" }, "locus": { "chromosome": "2", "start_pos": 32540426, "end_pos": 32538657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004156.1", "url": "https://www.ensembl.org/id/ENSGALT00010004156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002453.1", "url": "https://www.ensembl.org/id/ENSGALP00010002453.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gradients and forward spreading of vertebrate Hox gene expression detected using a Hox/lacZ transgene.", "journal": "Dev. Dyn.", "date": "2001", "authors": "Gaunt S J", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "reference": [ { "type": "PubMed", "id": "11357191", "url": "https://glygen.org/publication/PubMed/11357191" } ] }, { "title": "Additional enhancer copies, with intact cdx binding sites, anteriorize Hoxa-7/lacZ expression in mouse embryos: evidence in keeping with an instructional cdx gradient.", "journal": "The International journal of developmental biology", "date": "2004-09", "authors": "Gaunt Stephen J, Cockley Adam, Drage Deborah", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ], "reference": [ { "type": "PubMed", "id": "15470633", "url": "https://glygen.org/publication/PubMed/15470633" } ] }, { "title": "HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.", "journal": "Molecular biology reports", "date": "2009", "authors": "Chung N, Jee BK, Chae SW, Jeon YW, Lee KH, Rha HK", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ], "reference": [ { "type": "PubMed", "id": "17972163", "url": "https://glygen.org/publication/PubMed/17972163" } ] }, { "title": "HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL.", "journal": "Pediatric blood & cancer", "date": "2010-12-01", "authors": "Starkova Julia, Zamostna Blanka, Mejstrikova Ester, Krejci Roman, Drabkin Harry A, Trka Jan", "evidence": [ { "database": "RefSeq", "id": "NP_989926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989926" } ], "reference": [ { "type": "PubMed", "id": "20672366", "url": "https://glygen.org/publication/PubMed/20672366" } ] } ], "pathway": [ { "id": "gga:395290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395290", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "negative regulation of leukocyte migration", "id": "GO:0002686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002686", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "negative regulation of cell-matrix adhesion", "id": "GO:0001953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001953", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" }, { "name": "negative regulation of monocyte differentiation", "id": "GO:0045656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045656", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": "https://www.uniprot.org/uniprotkb/Q90VZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q90VZ9", "url": 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"cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GLW1-1", "uniprot_ac": "R4GLW1", "uniprot_id": "R4GLW1_CHICK", "mass": { "chemical_mass": 39234.0, "monoisotopic_mass": 39234.0 }, "refseq": { "ac": "XP_001233678", "name": "protein Wnt-16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233678" }, "gene_names": [ { "name": "WNT16", "type": "recommended", "evidence": [ { "id": "R4GLW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLW1" } ] }, { "name": "WNT16", "type": "synonym", "evidence": [ { "id": "XP_001233678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233678" } ] } ], "protein_names": [ { "name": "Protein Wnt", "type": "recommended", "evidence": [ { "id": "R4GLW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLW1/entry#names_and_taxonomy" } ] }, { "name": "protein Wnt-16", "type": "synonym", "evidence": [ { "id": "XP_001233678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233678" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001233678.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233678" } ] }, { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X506", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X506#function" }, { "database": "UniProtKB", "id": "RU003500", "url": "https://www.uniprot.org/uniprotkb/RU003500#function" }, { "database": "UniProtKB", "id": "R4GLW1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GLW1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WNT16", "url": "https://www.uniprot.org/uniprotkb/R4GLW1", "locus": { "chromosome": "1", "start_pos": 23406841, "end_pos": 23419250, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001305", "url": "https://www.ensembl.org/id/ENSGALG00010001305" } ] } } ], "crossref": [ { "id": "R4GLW1", "url": "https://alphafold.ebi.ac.uk/entry/R4GLW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028069", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028069", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19344", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19344", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427856", "url": "https://www.ncbi.nlm.nih.gov/gene/427856", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427856", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427856", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCWLQMP", "url": "https://omabrowser.org/oma/group/TCWLQMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X506", "url": "https://www.orthodb.org/?gene=A0A8V0X506", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GLW1", "url": "https://www.orthodb.org/?gene=R4GLW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3238698", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X506", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X506", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X506-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X506-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLW1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLW1-1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGAAIGRSLLRAAMLLALCPGAAGGTWMWLGIAAAGGPEKPGCSSPPLSPGQQELCRQKPELVPAIREGARLGLQECRSQFRHERWDCRPPPAAPRRPPAAFGQQLSSGTKESAFVYAVTAAGLVHAVTRSCSAGNVTECSCDTKLQGGGSASEGWHWGGCSDDIHYGMAFSRSFLDAPIRNASGKSGNGLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGRFLKDKYENSIQVSDKLKKKLRRKEKSQRKIPIQKEDLLYVNKSPNYCVEDQKLGIPGTQGRECNRTSDGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMTDVHTCK", "length": 360, "header": "tr|R4GLW1-1|R4GLW1_CHICK Isoform 1 of Protein Wnt OS=Gallus gallus OX=9031 GN=WNT16 PE=3 SV=2 CANONICAL=R4GLW1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X506-1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1/entry#A0A8V0X506-1", "sequence": { "sequence": "MRGHGARGRHRSKPAAGSDVARSLPRRCGRHVDVSSRARGVGGSGQRGAGPPVPALTGLFRRWLGIAAAGGPEKPGCSSPPLSPGQQELCRQKPELVPAIREGARLGLQECRSQFRHERWDCRPPPAAPRRPPAAFGQQLSSGTKESAFVYAVTAAGLVHAVTRSCSAGNVTECSCDTKLQGGGSASEGWHWGGCSDDIHYGMAFSRSFLDAPIRNASGKSGNGLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGRFLKDKYENSIQVSDKLKKKLRRKEKSQRKIPIQKEDLLYVNKSPNYCVEDQKLGIPGTQGRECNRTSDGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMTDVHTCK", "length": 392, "header": "tr|A0A8V0X506-1|R4GLW1_CHICK Computationally mapped isoform of Protein Wnt OS=Gallus gallus OX=9031 GN=WNT16 PE=3 SV=1 CANONICAL=R4GLW1-1" }, "locus": { "chromosome": "1", "start_pos": 23419051, "end_pos": 23409185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003019.1", "url": "https://www.ensembl.org/id/ENSGALT00010003019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001555.1", "url": "https://www.ensembl.org/id/ENSGALP00010001555.1" } ] } }, { "isoform_ac": "R4GLW1-1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1/entry#R4GLW1-1", "sequence": { "sequence": "MGRGAAIGRSLLRAAMLLALCPGAAGGTWMWLGIAAAGGPEKPGCSSPPLSPGQQELCRQKPELVPAIREGARLGLQECRSQFRHERWDCRPPPAAPRRPPAAFGQQLSSGTKESAFVYAVTAAGLVHAVTRSCSAGNVTECSCDTKLQGGGSASEGWHWGGCSDDIHYGMAFSRSFLDAPIRNASGKSGNGLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGRFLKDKYENSIQVSDKLKKKLRRKEKSQRKIPIQKEDLLYVNKSPNYCVEDQKLGIPGTQGRECNRTSDGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMTDVHTCK", "length": 360, "header": "tr|R4GLW1-1|R4GLW1_CHICK Isoform 1 of Protein Wnt OS=Gallus gallus OX=9031 GN=WNT16 PE=3 SV=2 CANONICAL=R4GLW1-1" }, "locus": { "chromosome": "1", "start_pos": 23419041, "end_pos": 23409185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003017.1", "url": "https://www.ensembl.org/id/ENSGALT00010003017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001553.1", "url": "https://www.ensembl.org/id/ENSGALP00010001553.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427856", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427856", "resource": "KEGG Pathway" }, { "id": "R-GGA-3238698", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "resource": "Reactome", "description": "WNT ligand biogenesis and trafficking" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140T847-1", "protein_name": "Protein Wnt", "gene_name": "WNT16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRAALLGLSRLCALWAAVLALFPCGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCLVAAASAPGTSPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRKFLDFPIKNTTAKESKVLLAMNLHNNEAGRQAVAKLMSLDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSVQISDKIKRKMHRREKDQRKIPIRKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK", "length": 362 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A5WVL3-1", "protein_name": "Protein Wnt", "gene_name": "wnt16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNTGCGIHAVHHLFLIWLSVYPLCSQGSWMWLGITSVGVPEKLGCAHLPLSHKQKELCARKPHLLPSVKEGARLGITECQTQFRHERWNCSTRRDPNVFGYELTSGTKETAFIHAVMAAGLVHAVTRSCSAGNMTECSCDTSLLGSGSPTEGWHWGGCSDDIAFGTSFSRRFIDSAAKNTSTRGEEALLIMKQHNSEAGRQAVAKTMLTDCRCHGVSGSCAVKTCWRTMAAFERVGAYLKDRYETSVHVVDRSKRKVRRKDKEQRHVPITKDELIFFNKSPNYCLEDRRLGVTGTRGRKCNRTSAGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMNDMHTCK", "length": 356 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A3K6-1", "protein_name": "Protein Wnt", "gene_name": "Wnt16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRAALLALPSLCALWAAVLSLLPCGTQGNWMWLGIASFGVPEKLGCSGLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMVATATSTQLATAPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTTLQNSGSASEGWHWGGCSDDVQYGMWFSRKFLDLPVRNTTEKESKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGYFLKDKYENSIQISDKTKRKMRRREKDQRQTPILKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTSLNHRVFFLLTSLGPFKNPWQEYSKYRGECQQQTTELRIEPPLKESEKELEELEGA", "length": 418 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SJF8-1", "protein_name": "Protein Wnt", "gene_name": "WNT16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRAALLGLSRLCALWAALLALFPCGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFKHERWNCLVATASQQGTSPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRRFLDFPIRNTTGKESKVLLAMNLHNNEAGRQAVAKLMSLDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSVQISDKIKKKMLRRDKDQRKIPIRKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK", "length": 362 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IDN6-1", "protein_name": "Protein Wnt", "gene_name": "Wnt16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDRAALLALPSLCALWAAVLSLFPCGTQGNWMWLGIASFGVPEKLGCDGLPLNSRQKELCKRKPYLLPSIHEGARLGIQECKSQFRHERWNCMVATATSVPLATSPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTALQNGGSPSEGWHWGGCSDDVQYGMWFSRKFLDFPIRNTTAKESRVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHFLKDKYENSIQISDKTKRKMRRREKDQRQTPIHKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK", "length": 364 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9QYS1-1", "protein_name": "Protein Wnt-16", "gene_name": "Wnt16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRAALLALPSLCALWAAVLSLLPCGTQGNWMWLGIASFGVPEKLGCADLPLNSRQKELCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMVATTTSTQLATAPLFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSPSEGWHWGGCSDDVQYGMWFSRKFLDLPIRNTTGKESRVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHFLKDKYENSIQISDKTKRKMRRREKDQRQTPILKDDLLYVHKSPNYCVENKKLGIPGTQGRECNRTSGGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK", "length": 364 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBV4-1", "protein_name": "Protein Wnt-16", "gene_name": "WNT16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK", "length": 365 }, "evidence": [ { "id": "R4GLW1", "url": "https://omabrowser.org/oma/group/R4GLW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "R4GLW1", "url": "https://www.uniprot.org/uniprotkb/R4GLW1" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { 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} ], "protein_names": [ { "name": "cAMP-dependent protein kinase inhibitor alpha", "type": "recommended", "evidence": [ { "id": "Q90641", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#names_and_taxonomy" } ] }, { "name": "PKI-alpha", "type": "synonym", "evidence": [ { "id": "NP_990705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990705" }, { "id": "Q90641", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#names_and_taxonomy" } ] }, { "name": "cAMP-dependent protein kinase inhibitor alpha", "type": "synonym", "evidence": [ { "id": "NP_990705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990705" } ] }, { "name": "cAMP-dependent protein kinase inhibitor protein", "type": "synonym", "evidence": [ { "id": "NP_990705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990705" } ] }, { "name": "cAMP-dependent protein kinase inhibitor, kidney isoform", "type": "synonym", "evidence": [ { "id": "Q90641", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01073427.1, HAEK01084974.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000043.1. On Aug 30, 2004 this sequence version replaced XP_429302.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990705", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990705" } ] }, { "annotation": "Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKH6#function" }, { "database": "UniProtKB", "id": "ARBA00002844", "url": "https://www.uniprot.org/uniprotkb/ARBA00002844#function" }, { "database": "UniProtKB", "id": "A0A8V0X9G9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9G9#function" }, { "database": "UniProtKB", "id": "A0A8V0XDK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDK1#function" }, { "database": "UniProtKB", "id": "A0A8V0XDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDK8#function" }, { 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90641", "url": "https://www.uniprot.org/uniprotkb/Q90641", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90641-1", "url": "https://www.uniprot.org/uniprotkb/Q90641-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 76, "header": "sp|Q90641-1|IPKA_CHICK Isoform 1 of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=3 CANONICAL=Q90641-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X9G9-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#A0A8V0X9G9-1", "sequence": { "sequence": "MPPERREFRSSSCRRDVGVKRSWELLLVEASAALGTVPTGPRLWEGKKGGRKEDALSRLLGRADSQGGRISIWRALSLEPFCEPRTRVLLCGYLLAMTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 172, "header": "tr|A0A8V0X9G9-1|IPKA_CHICK Computationally mapped isoform of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=1 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119939858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007916.1", "url": "https://www.ensembl.org/id/ENSGALT00010007916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004751.1", "url": "https://www.ensembl.org/id/ENSGALP00010004751.1" } ] } }, { "isoform_ac": "A0A8V0XDK1-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#A0A8V0XDK1-1", "sequence": { "sequence": "MPPERREFRSSSCRRDVGVKRSWELLLVEVLLCGYLLAMTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 114, "header": "tr|A0A8V0XDK1-1|IPKA_CHICK Computationally mapped isoform of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=1 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119939858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007915.1", "url": "https://www.ensembl.org/id/ENSGALT00010007915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004750.1", "url": "https://www.ensembl.org/id/ENSGALP00010004750.1" } ] } }, { "isoform_ac": "A0A8V0XDK8-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#A0A8V0XDK8-1", "sequence": { "sequence": "MWLSASSLPSARSTLLRAVLPAGGGVPAAGQREGLRQVLLCGYLLAMTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 122, "header": "tr|A0A8V0XDK8-1|IPKA_CHICK Computationally mapped isoform of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=1 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119940250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007921.1", "url": "https://www.ensembl.org/id/ENSGALT00010007921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004755.1", "url": "https://www.ensembl.org/id/ENSGALP00010004755.1" } ] } }, { "isoform_ac": "A0A8V0XJ40-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#A0A8V0XJ40-1", "sequence": { "sequence": "MTSITLILKKQSLVLGNSEINVLLCGYLLAMTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 106, "header": "tr|A0A8V0XJ40-1|IPKA_CHICK Computationally mapped isoform of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=1 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119962003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007913.1", "url": "https://www.ensembl.org/id/ENSGALT00010007913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004748.1", "url": "https://www.ensembl.org/id/ENSGALP00010004748.1" } ] } }, { "isoform_ac": "A0A8V0XKH6-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#A0A8V0XKH6-1", "sequence": { "sequence": "MRCPSSPTGREREPPTQNPSVPHSRIWGHSRAAPARPEAAGGAGGAWRPHAGTNYNGISFRTDTRAHSTALPAGGCPSAPGPRASLVLLCGYLLAMTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 171, "header": "tr|A0A8V0XKH6-1|IPKA_CHICK Computationally mapped isoform of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=1 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119939237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007918.1", "url": "https://www.ensembl.org/id/ENSGALT00010007918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004752.1", "url": "https://www.ensembl.org/id/ENSGALP00010004752.1" } ] } }, { "isoform_ac": "Q90641-1", "url": "https://www.uniprot.org/uniprotkb/Q90641/entry#Q90641-1", "sequence": { "sequence": "MTDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDINKAEGEGDAQRNPSEQTGEAQGEAAKQES", "length": 76, "header": "sp|Q90641-1|IPKA_CHICK Isoform 1 of cAMP-dependent protein kinase inhibitor alpha OS=Gallus gallus OX=9031 GN=PKIA PE=3 SV=3 CANONICAL=Q90641-1" }, "locus": { "chromosome": "2", "start_pos": 119975658, "end_pos": 119970889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007914.1", "url": "https://www.ensembl.org/id/ENSGALT00010007914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004749.1", "url": "https://www.ensembl.org/id/ENSGALP00010004749.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genomic cloning, structure, and regulatory elements of the 1 alpha, 25(OH)2D3 down-regulated gene for cyclic AMP-dependent protein kinase inhibitor.", "journal": "Biochim. Biophys. Acta", "date": "1999", "authors": "Rowland-Goldsmith M A, Holmquist B, Henry H L", "evidence": [ { "database": "UniProtKB", "id": "Q90641", "url": "https://www.uniprot.org/uniprotkb/Q90641" } ], "reference": [ { "type": "PubMed", "id": "10524218", "url": "https://glygen.org/publication/PubMed/10524218" } ] }, { "title": "Cloning and sequencing of the cDNA encoding the avian kidney cAMP-dependent protein kinase inhibitor protein.", "journal": "Gene", "date": "1995", "authors": "Marchetto G S, Henry H L", "evidence": [ { "database": "UniProtKB", "id": "Q90641", "url": "https://www.uniprot.org/uniprotkb/Q90641" } ], "reference": [ { "type": "PubMed", "id": "7607559", "url": "https://glygen.org/publication/PubMed/7607559" } ] } ], "pathway": [ { "id": "gga:396333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FGF5-1", "protein_name": "cAMP-dependent protein kinase inhibitor alpha", "gene_name": "PKIA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLCHDKNSLFSYFATIFSGVKLACHPVTIWLMTQCHYKNHVSSFIDPTLLGSIYVDALICFHRGDSLLCGYLLAMTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRNSTEQSGEAQGEAAKSES", "length": 150 }, "evidence": [ { "id": "Q90641", "url": "https://omabrowser.org/oma/group/Q90641/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P61925-1", "protein_name": "cAMP-dependent protein kinase inhibitor alpha", "gene_name": "PKIA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES", "length": 76 }, "evidence": [ { "id": "Q90641", "url": "https://omabrowser.org/oma/group/Q90641/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63248-1", "protein_name": "cAMP-dependent protein kinase inhibitor alpha", "gene_name": "Pkia", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEDDGQRSSTEQSGEAQGEAAKSES", "length": 76 }, "evidence": [ { "id": "Q90641", "url": "https://omabrowser.org/oma/group/Q90641/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SX13-1", "protein_name": "cAMP-dependent protein kinase inhibitor alpha", "gene_name": "PKIA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRNSTEQSGEAQGEAAKSES", "length": 76 }, "evidence": [ { "id": "Q90641", "url": "https://omabrowser.org/oma/group/Q90641/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q90641", 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class A domain-containing protein 4 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942" }, "gene_names": [ { "name": "LDLRAD4", "type": "recommended", "evidence": [ { "id": "F6RPR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ] }, { "name": "C18orf1", "type": "synonym", "evidence": [ { "id": "XP_015137942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942" } ] }, { "name": "C2H18ORF1", "type": "synonym", "evidence": [ { "id": "XP_015137942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942" } ] }, { "name": "LDLRAD4", "type": "synonym", "evidence": [ { "id": "XP_015137942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942" } ] } ], "protein_names": [ { "name": "Low density lipoprotein receptor class A domain containing 4", "type": "synonym", "evidence": [ { "id": "F6RPR8", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LDLRAD4", "url": "https://www.uniprot.org/uniprotkb/F6RPR8", "locus": { "chromosome": "2", "start_pos": 96195032, "end_pos": 96338361, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001442", "url": "https://www.ensembl.org/id/ENSGALG00010001442" } ] } } ], "crossref": [ { "id": "F6RPR8", "url": "https://alphafold.ebi.ac.uk/entry/F6RPR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013886", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013886", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421044", "url": "https://www.ncbi.nlm.nih.gov/gene/421044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421044", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XB94", "url": "https://www.orthodb.org/?gene=A0A8V0XB94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XB99", "url": "https://www.orthodb.org/?gene=A0A8V0XB99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYM2", "url": "https://www.orthodb.org/?gene=E1BYM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RPR8", "url": "https://www.orthodb.org/?gene=F6RPR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16514:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16514:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XB94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYM2", "url": "https://www.uniprot.org/uniprotkb/E1BYM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BYM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPR8-1", "url": "https://www.uniprot.org/uniprotkb/F6RPR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSREQLNSTAVKDARLRDLLLERAELEFVQIIIIIVVITVMVVVIICLLNHYKLSTRSFINRQSQSRRQEDTLQTEGCLWPSESSVSRQGASEIMYAPRSRDRFTAPSFMQRDRFSRFQPTYPYMQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGGPCPPSSNSGISATNYSSNGRMEGPPPTYSEVMGHYPGSSFFHHQHSNAPPSSQRGSRLQFQQNNSESTIVPSKGQDRKPGNLV", "length": 273, "header": "tr|F6RPR8-1|F6RPR8_CHICK Isoform 1 of Low density lipoprotein receptor class A domain containing 4 OS=Gallus gallus OX=9031 GN=LDLRAD4 PE=3 SV=1 CANONICAL=F6RPR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XB94-1", "url": "https://www.uniprot.org/uniprotkb/F6RPR8/entry#A0A8V0XB94-1", "sequence": { "sequence": "MPGPRPVWKSALGGQRTELEFVQIIIIIVVITVMVVVIICLLNHYKLSTRSFINRQSQSRRQEDTLQTIMYAPRSRDRFTAPSFMQRDRFSRFQPTYPYMQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGGPCPPSSNSGISATNYSSNGRMEGPPPTYSEVMGHYPGSSFFHHQHSNAPPSSQRGSRLQFQQNNSESTIVPSKGQDRKPGNLV", "length": 248, "header": "tr|A0A8V0XB94-1|F6RPR8_CHICK Computationally mapped isoform of Low density lipoprotein receptor class A domain containing 4 OS=Gallus gallus OX=9031 GN=LDLRAD4 PE=3 SV=1 CANONICAL=F6RPR8-1" }, "locus": { "chromosome": "2", "start_pos": 96216347, "end_pos": 96203691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003321.1", "url": "https://www.ensembl.org/id/ENSGALT00010003321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001767.1", "url": "https://www.ensembl.org/id/ENSGALP00010001767.1" } ] } }, { "isoform_ac": "A0A8V0XB99-1", "url": "https://www.uniprot.org/uniprotkb/F6RPR8/entry#A0A8V0XB99-1", "sequence": { "sequence": "MWEAELEFVQIIIIIVVITVMVVVIICLLNHYKLSTRSFINRQSQSRRQEDTLQTEGCLWPSESSVSRQGASEIMYAPRSRDRFTAPSFMQRDRFSRFQPTYPYMQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGGPCPPSSNSGISATNYSSNGRMEGPPPTYSEVMGHYPGSSFFHHQHSNAPPSSQRGSRLQFQQNNSESTIVPSKGQDRKPGNLV", "length": 253, "header": "tr|A0A8V0XB99-1|F6RPR8_CHICK Computationally mapped isoform of Low density lipoprotein receptor class A domain containing 4 OS=Gallus gallus OX=9031 GN=LDLRAD4 PE=3 SV=1 CANONICAL=F6RPR8-1" }, "locus": { "chromosome": "2", "start_pos": 96218775, "end_pos": 96203691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003326.1", "url": "https://www.ensembl.org/id/ENSGALT00010003326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001772.1", "url": "https://www.ensembl.org/id/ENSGALP00010001772.1" } ] } }, { "isoform_ac": "E1BYM2-1", "url": "https://www.uniprot.org/uniprotkb/F6RPR8/entry#E1BYM2-1", "sequence": { "sequence": "MVVVIICLLNHYKLSTRSFINRQSQSRRQEDTLQTEGCLWPSESSVSRQGASEIMYAPRSRDRFTAPSFMQRDRFSRFQPTYPYMQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGGPCPPSSNSGISATNYSSNGRMEGPPPTYSEVMGHYPGSSFFHHQHSNAPPSSQRGSRLQFQQNNSESTIVPSKGQDRKPGNLV", "length": 233, "header": "tr|E1BYM2-1|F6RPR8_CHICK Computationally mapped isoform of Low density lipoprotein receptor class A domain containing 4 OS=Gallus gallus OX=9031 GN=LDLRAD4 PE=3 SV=2 CANONICAL=F6RPR8-1" }, "locus": { "chromosome": "2", "start_pos": 96214639, "end_pos": 96203691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003329.1", "url": "https://www.ensembl.org/id/ENSGALT00010003329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001775.1", "url": "https://www.ensembl.org/id/ENSGALP00010001775.1" } ] } }, { "isoform_ac": "F6RPR8-1", "url": "https://www.uniprot.org/uniprotkb/F6RPR8/entry#F6RPR8-1", "sequence": { "sequence": "MSREQLNSTAVKDARLRDLLLERAELEFVQIIIIIVVITVMVVVIICLLNHYKLSTRSFINRQSQSRRQEDTLQTEGCLWPSESSVSRQGASEIMYAPRSRDRFTAPSFMQRDRFSRFQPTYPYMQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGGPCPPSSNSGISATNYSSNGRMEGPPPTYSEVMGHYPGSSFFHHQHSNAPPSSQRGSRLQFQQNNSESTIVPSKGQDRKPGNLV", "length": 273, "header": "tr|F6RPR8-1|F6RPR8_CHICK Isoform 1 of Low density lipoprotein receptor class A domain containing 4 OS=Gallus gallus OX=9031 GN=LDLRAD4 PE=3 SV=1 CANONICAL=F6RPR8-1" }, "locus": { "chromosome": "2", "start_pos": 96217376, "end_pos": 96203691, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003323.1", "url": "https://www.ensembl.org/id/ENSGALT00010003323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001769.1", "url": "https://www.ensembl.org/id/ENSGALP00010001769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421044", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "R-SMAD binding", "id": "GO:0070412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070412", "evidence": [ { "database": "UniProtKB", "id": "F6RPR8", "url": "https://www.uniprot.org/uniprotkb/F6RPR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RPR8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RPR8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RPR8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GHN1-1", "uniprot_ac": "R4GHN1", "uniprot_id": "R4GHN1_CHICK", "mass": { "chemical_mass": 17906.0, "monoisotopic_mass": 17906.0 }, "refseq": { "ac": "NP_001265073", "name": "arachidonate 5-lipoxygenase-activating protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265073" }, "gene_names": [ { "name": "ALOX5AP", "type": "recommended", "evidence": [ { "id": "R4GHN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ] }, { "name": "ALOX5AP", "type": "synonym", "evidence": [ { "id": "NP_001265073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265073" } ] } ], "protein_names": [ { "name": "Arachidonate 5-lipoxygenase-activating protein", "type": "recommended", "evidence": [ { "id": "R4GHN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHN1/entry#names_and_taxonomy" } ] }, { "name": "arachidonate 5-lipoxygenase-activating protein", "type": "synonym", "evidence": [ { "id": "NP_001265073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265073" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01012924.1, BX931442.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On May 12, 2013 this sequence version replaced XP_001233119.1. Sequence Note: This RefSeq record was created with transcript data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265073" } ] }, { "annotation": "Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XMD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD1#function" }, { "database": "UniProtKB", "id": "ARBA00037558", "url": "https://www.uniprot.org/uniprotkb/ARBA00037558#function" }, { "database": "UniProtKB", "id": "A0A8V0XMD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD6#function" }, { "database": "UniProtKB", "id": "A0A8V0XTN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTN9#function" }, { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALOX5AP", "url": "https://www.uniprot.org/uniprotkb/R4GHN1", "locus": { "chromosome": "1", "start_pos": 174921125, "end_pos": 174930847, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006942", "url": "https://www.ensembl.org/id/ENSGALG00010006942" } ] } } ], "crossref": [ { "id": "R4GHN1", "url": "https://alphafold.ebi.ac.uk/entry/R4GHN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026781", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770904", "url": "https://www.ncbi.nlm.nih.gov/gene/770904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770904", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NAPWHTQ", "url": "https://omabrowser.org/oma/group/NAPWHTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMD1", "url": "https://www.orthodb.org/?gene=A0A8V0XMD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMD6", "url": "https://www.orthodb.org/?gene=A0A8V0XMD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTN9", "url": "https://www.orthodb.org/?gene=A0A8V0XTN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GHN1", "url": "https://www.orthodb.org/?gene=R4GHN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10250:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10250:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2142688", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2142691", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2142700", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHN1-1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQETLGSVVLLAIVTLISVIQNAFFASKLEHESKHCNGKGIQRPGSSAFERVYTANQNCGHTYPTFLAVLWCAGLLCSQAPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYLFGKRIILFLFLMSVAGILNYYLIYFFGSDFEIHIKTITSAISPLLLIP", "length": 161, "header": "tr|R4GHN1-1|R4GHN1_CHICK Isoform 1 of Arachidonate 5-lipoxygenase-activating protein OS=Gallus gallus OX=9031 GN=ALOX5AP PE=1 SV=1 CANONICAL=R4GHN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMD1-1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1/entry#A0A8V0XMD1-1", "sequence": { "sequence": "MQASLLRKSVLNLINFLQPYPTILAENAAQHPDKGVGFAPDALRLPRLKKLAFFASKLEHESKHCNGKGIQRPGSSAFERVYTANQNCGHTYPTFLAVLWCAGLLCSQAPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYLFGKRIILFLFLMSVAGILNYYLIYFFGSDFEIHIKTITSAISPLLLIP", "length": 189, "header": "tr|A0A8V0XMD1-1|R4GHN1_CHICK Computationally mapped isoform of Arachidonate 5-lipoxygenase-activating protein OS=Gallus gallus OX=9031 GN=ALOX5AP PE=1 SV=2 CANONICAL=R4GHN1-1" }, "locus": { "chromosome": "1", "start_pos": 174928427, "end_pos": 174921818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016478.1", "url": "https://www.ensembl.org/id/ENSGALT00010016478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009355.1", "url": "https://www.ensembl.org/id/ENSGALP00010009355.1" } ] } }, { "isoform_ac": "A0A8V0XMD6-1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1/entry#A0A8V0XMD6-1", "sequence": { "sequence": "LRPSLPPSALAGLSCCCGCTVHPTARSQNGPGDPGERRPARHCHLDQRHPERQNCGHTYPTFLAVLWCAGLLCSQAPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYLFGKRIILFLFLMSVAGILNYYLIYFFGSDFEIHIKTITSAISPLLLIP", "length": 156, "header": "tr|A0A8V0XMD6-1|R4GHN1_CHICK Computationally mapped isoform of Arachidonate 5-lipoxygenase-activating protein OS=Gallus gallus OX=9031 GN=ALOX5AP PE=1 SV=1 CANONICAL=R4GHN1-1" }, "locus": { "chromosome": "1", "start_pos": 174929104, "end_pos": 174921818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016489.1", "url": "https://www.ensembl.org/id/ENSGALT00010016489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009360.1", "url": "https://www.ensembl.org/id/ENSGALP00010009360.1" } ] } }, { "isoform_ac": "A0A8V0XTN9-1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1/entry#A0A8V0XTN9-1", "sequence": { "sequence": "GLRDGRHRAAGGSSRALRGLSCCCGCTVHPTARSQNGPGDPGERRPARHCHLDQRHPERQNCGHTYPTFLAVLWCAGLLCSQAPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYLFGKRIILFLFLMSVAGILNYYLIYFFGSDFEIHIKTITSAISPLLLIP", "length": 163, "header": "tr|A0A8V0XTN9-1|R4GHN1_CHICK Computationally mapped isoform of Arachidonate 5-lipoxygenase-activating protein OS=Gallus gallus OX=9031 GN=ALOX5AP PE=1 SV=1 CANONICAL=R4GHN1-1" }, "locus": { "chromosome": "1", "start_pos": 174930810, "end_pos": 174921818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016493.1", "url": "https://www.ensembl.org/id/ENSGALT00010016493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009362.1", "url": "https://www.ensembl.org/id/ENSGALP00010009362.1" } ] } }, { "isoform_ac": "R4GHN1-1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1/entry#R4GHN1-1", "sequence": { "sequence": "MDQETLGSVVLLAIVTLISVIQNAFFASKLEHESKHCNGKGIQRPGSSAFERVYTANQNCGHTYPTFLAVLWCAGLLCSQAPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYLFGKRIILFLFLMSVAGILNYYLIYFFGSDFEIHIKTITSAISPLLLIP", "length": 161, "header": "tr|R4GHN1-1|R4GHN1_CHICK Isoform 1 of Arachidonate 5-lipoxygenase-activating protein OS=Gallus gallus OX=9031 GN=ALOX5AP PE=1 SV=1 CANONICAL=R4GHN1-1" }, "locus": { "chromosome": "1", "start_pos": 174929019, "end_pos": 174921818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016484.1", "url": "https://www.ensembl.org/id/ENSGALT00010016484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009357.1", "url": "https://www.ensembl.org/id/ENSGALP00010009357.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770904", "resource": "KEGG Pathway" }, { "id": "R-GGA-2142688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142688", "resource": "Reactome", "description": "Synthesis of 5-eicosatetraenoic acids" }, { "id": "R-GGA-2142691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142691", "resource": "Reactome", "description": "Synthesis of Leukotrienes (LT) and Eoxins (EX)" }, { "id": "R-GGA-2142700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142700", "resource": "Reactome", "description": "Biosynthesis of Lipoxins (LX)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TIT9-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQEAMGNIVLLAIVTLISVVQNAFFAHKVEHESKTHNGRSFQRTGTPAFERVYTANQNCVDAYPTFLVVLWSAGLFCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSLAGIFNYFLILFFGSDFENYIKTITTTVSPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GWG0-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "Alox5ap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQETVGNVVLLVIVTLISVVQNAFFAHKVEHESKMQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLLVRQKYFVGYLGERTQSTPGYIFGKRIISFLFLMSLAGVLNHYLIFFFGSDFENYIRTVTTTISPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P20291-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "Alox5ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQEAVGNVVLLAIVTLISVVQNAFFAHKVELESKAQSGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSLAGILNHYLIFFFGSDFENYIRTITTTISPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20292-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30355-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "Alox5ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQEAVGNVVLLALVTLISVVQNAFFAHKVEHESKAHNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSFAGILNHYLIFFFGSDFENYIRTVSTTISPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q148F2-1", "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDQEAVGNIVLLAIVTLISVVQNGFFAHKVEHESKTHNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVMLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFAMSLAGILNYFFIALFGSDFENYIKTVTTTISPLLLIP", "length": 161 }, "evidence": [ { "id": "R4GHN1", "url": "https://omabrowser.org/oma/group/R4GHN1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "leukotriene-C4 synthase activity", "id": "GO:0004464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004464", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "arachidonate binding", "id": "GO:0050544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050544", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": 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membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "leukotriene biosynthetic process", "id": "GO:0019370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019370", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" }, { "name": "protein homotrimerization", "id": "GO:0070207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070207", "evidence": [ { "database": "UniProtKB", "id": "R4GHN1", "url": "https://www.uniprot.org/uniprotkb/R4GHN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GI64-1", "uniprot_ac": "R4GI64", "uniprot_id": "R4GI64_CHICK", "mass": { "chemical_mass": 86075.0, "monoisotopic_mass": 86075.0 }, "refseq": { "ac": "NP_001012545", "name": "mitochondrial inner membrane m-AAA protease component paraplegin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" }, "gene_names": [ { "name": "SPG7", "type": "recommended", "evidence": [ { "id": "R4GI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ] }, { "name": "SPG7", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] } ], "protein_names": [ { "name": "SPG7, paraplegin matrix AAA peptidase subunit", "type": "synonym", "evidence": [ { "id": "R4GI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI64/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial inner membrane m-AAA protease component paraplegin", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] }, { "name": "paraplegin", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] }, { "name": "spastic paraplegia 7 (pure and complicated autosomal recessive)", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] }, { "name": "spastic paraplegia 7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] }, { "name": "spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)", "type": "synonym", "evidence": [ { "id": "NP_001012545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPG7", "url": "https://www.uniprot.org/uniprotkb/R4GI64", "locus": { "chromosome": "11", "start_pos": 18380959, "end_pos": 18349575, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007989", "url": "https://www.ensembl.org/id/ENSGALG00010007989" } ] } } ], "crossref": [ { "id": "R4GI64", "url": "https://alphafold.ebi.ac.uk/entry/R4GI64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028363", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028363", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19501", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19501", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415843", "url": "https://www.ncbi.nlm.nih.gov/gene/415843", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415843", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415843", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMKSMKS", "url": "https://omabrowser.org/oma/group/RMKSMKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV92", "url": "https://www.orthodb.org/?gene=A0A8V0XV92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y3A4", "url": "https://www.orthodb.org/?gene=A0A8V0Y3A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GI64", "url": "https://www.orthodb.org/?gene=R4GI64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43655:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43655:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8949664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XV92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI64-1", "url": "https://www.uniprot.org/uniprotkb/R4GI64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLRFLLLRGRCGWRPNPAAWARPRPRGPQGFLSQTASPTCQGLGGALVKQHVLRDPARLWNLLGSTYYFTTSGCQRSNHKNGGFKKKSPKEEEEEEKRRKRENQMHLERLRALLIITLIVLLFRFTVSENREGTNISWNYFINEMLSKGEVQRIEVVPESDIVEIYLHPGGTPHGQVNVTLLYTMRVANIDKFEEKLRAAEDELNIDERERIPVSYKHPGFYGNDVISLLVTLVAVSMLWSIFRLIRVAGRAGGFNAFNQLKMARFTIVDGKSGKGIGFKDVAGMHEAKMEVKEFVDYLKNPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFREAQARAPCIVYIDEIDAVGKKRSTNVSGFANAEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKGLKLIQDASFYSQHLAELTPGFSGADIANICNEAALHAAREGHKSIDTFNFEYAVERVIAGTAKRNKILSPEERKVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLFTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLKRVTKIAYSMVKQYGMVPSIGQISFPDGESTVGIGRRPFSQGLQQMMDHEAKVLVAQAYRRTEKLLLDNRDKLQTLSNALLEKEVINYDDIEALIGPPPYGPKKMIAPQSWLQAERDKQDTRDEEMPQQPPNHEEEEEPRLRPV", "length": 768, "header": "tr|R4GI64-1|R4GI64_CHICK Isoform 1 of SPG7, paraplegin matrix AAA peptidase subunit OS=Gallus gallus OX=9031 GN=SPG7 PE=1 SV=3 CANONICAL=R4GI64-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XV92-1", "url": "https://www.uniprot.org/uniprotkb/R4GI64/entry#A0A8V0XV92-1", "sequence": { "sequence": "MALLRFLLLRGRCGWRPNPAAWARPRPRGPQGFLSQTASPTCQGLGGALVKQHVLRDPARLWNLLEEEKRRKRENQMHLERLRALLIITLIVLLFRFTVSENREGTNISWNYFINEMLSKGEVQRIEVVPESDIVEIYLHPGGTPHGQVNVTLLYTMRVANIDKFEEKLRAAEDELNIDERERIPVSYKHPGFYGNDVISLLVTLVAVSMLWSIFRLIRVAGRAGGFNAFNQLKMARFTIVDGKSGKGIGFKDVAGMHEAKMEVKEFVDYLKNPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFREAQARAPCIVYIDEIDAVGKKRSTNVSGFANAEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKGLKLIQDASFYSQHLAELTPGFSGADIANICNEAALHAAREGHKSIDTFNFEYAVERVIAGTAKRNKILSPEERKVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLFTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLKRVTKIAYSMVKQYGMVPSIGQISFPDGESTVGIGRRPFSQGLQQMMDHEAKVLVAQAYRRTEKLLLDNRDKLQTLSNALLEKEVINYDDIEALIGPPPYGPKKMIAPQSWLQAERDKQDTRDEEMPQQPPNHEEEEEPRLRPV", "length": 738, "header": "tr|A0A8V0XV92-1|R4GI64_CHICK Computationally mapped isoform of SPG7, paraplegin matrix AAA peptidase subunit OS=Gallus gallus OX=9031 GN=SPG7 PE=1 SV=1 CANONICAL=R4GI64-1" }, "locus": { "chromosome": "11", "start_pos": 18379594, "end_pos": 18349715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019047.1", "url": "https://www.ensembl.org/id/ENSGALT00010019047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010596.1", "url": "https://www.ensembl.org/id/ENSGALP00010010596.1" } ] } }, { "isoform_ac": "A0A8V0Y3A4-1", "url": "https://www.uniprot.org/uniprotkb/R4GI64/entry#A0A8V0Y3A4-1", "sequence": { "sequence": "MALLRFLLLRGRCGWRPNPAAWARPRPRGPQGFLSQTASPTCQGLGGALVKQHVLRDPARLWNLLGSTYYFTTSGCQRSNHKNGGFKKKSPKEEEEEEKRRKRENQMHLERLRALLIITLIVLLFRFTVSENREGTNISWNYFINEMLSKGEVQRIEVVPESDIVEIYLHPGGTPHGQVNVTLLYTMRVANIDKFEEKLRAAEDELNIDERERIPVSYKHPGFYGNDVISLLVTLVAVSMLWSIFRLIRVAGRAGGFNAFNPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFREAQARAPCIVYIDEIDAVGKKRSTNVSGFANAEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKGLKLIQDASFYSQHLAELTPGFSGADIANICNEAALHAAREGHKSIDTFNFEYAVERVIAGTAKRNKILSPEERKVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLFTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLKRVTKIAYSMVKQYGMVPSIGQISFPDGESTVGIGRRPFSQGLQQMMDHEAKVLVAQAYRRTEKLLLDNRDKLQTLSNALLEKEVINYDDIEALIGPPPYGPKKMIAPQSWLQAERDKQDTRDEEMPQQPPNHEEEEEPRLRPV", "length": 726, "header": "tr|A0A8V0Y3A4-1|R4GI64_CHICK Computationally mapped isoform of SPG7, paraplegin matrix AAA peptidase subunit OS=Gallus gallus OX=9031 GN=SPG7 PE=1 SV=1 CANONICAL=R4GI64-1" }, "locus": { "chromosome": "11", "start_pos": 18379594, "end_pos": 18349715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019044.1", "url": "https://www.ensembl.org/id/ENSGALT00010019044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010593.1", "url": "https://www.ensembl.org/id/ENSGALP00010010593.1" } ] } }, { "isoform_ac": "R4GI64-1", "url": "https://www.uniprot.org/uniprotkb/R4GI64/entry#R4GI64-1", "sequence": { "sequence": "MALLRFLLLRGRCGWRPNPAAWARPRPRGPQGFLSQTASPTCQGLGGALVKQHVLRDPARLWNLLGSTYYFTTSGCQRSNHKNGGFKKKSPKEEEEEEKRRKRENQMHLERLRALLIITLIVLLFRFTVSENREGTNISWNYFINEMLSKGEVQRIEVVPESDIVEIYLHPGGTPHGQVNVTLLYTMRVANIDKFEEKLRAAEDELNIDERERIPVSYKHPGFYGNDVISLLVTLVAVSMLWSIFRLIRVAGRAGGFNAFNQLKMARFTIVDGKSGKGIGFKDVAGMHEAKMEVKEFVDYLKNPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGSEFVEVIGGLGAARVRSLFREAQARAPCIVYIDEIDAVGKKRSTNVSGFANAEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHIFIDLPTLQERREIFEQHLKGLKLIQDASFYSQHLAELTPGFSGADIANICNEAALHAAREGHKSIDTFNFEYAVERVIAGTAKRNKILSPEERKVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILPREQYLFTKEQLLERMCMALGGRVSEAITFNKVTTGAQDDLKRVTKIAYSMVKQYGMVPSIGQISFPDGESTVGIGRRPFSQGLQQMMDHEAKVLVAQAYRRTEKLLLDNRDKLQTLSNALLEKEVINYDDIEALIGPPPYGPKKMIAPQSWLQAERDKQDTRDEEMPQQPPNHEEEEEPRLRPV", "length": 768, "header": "tr|R4GI64-1|R4GI64_CHICK Isoform 1 of SPG7, paraplegin matrix AAA peptidase subunit OS=Gallus gallus OX=9031 GN=SPG7 PE=1 SV=3 CANONICAL=R4GI64-1" }, "locus": { "chromosome": "11", "start_pos": 18379594, "end_pos": 18349715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019045.1", "url": "https://www.ensembl.org/id/ENSGALT00010019045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010594.1", "url": "https://www.ensembl.org/id/ENSGALP00010010594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415843", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415843", "resource": "KEGG Pathway" }, { "id": "R-GGA-8949664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "resource": "Reactome", "description": "Processing of SMDT1" }, { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GRR9-1", "protein_name": "Mitochondrial inner membrane m-AAA protease component paraplegin", "gene_name": "Spg7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAALLLLRALRQIPEPGPRRLWGQPWSRHPGLPSGSGSRRPYMVRGTPVGLSAAGGQAPQNLIFRILTPSFGGISGLLLKQHIVPNAIRLWQLSGSTYYFNTSRMKQKNKDNNKPKGKAPEDDEEERRRKEREDQMYRERLRTLFIIAVVMSLLNSLSTSGGSISWTDFVNEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESKDRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLTGMTGREGGFSAFNQLKMARFTIVDGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLVGIGRRPFSQGLQQLMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKEKQALAEEEAPAP", "length": 781 }, "evidence": [ { "id": "R4GI64", "url": "https://omabrowser.org/oma/group/R4GI64/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ULF4-1", "protein_name": "Mitochondrial inner membrane m-AAA protease component paraplegin", "gene_name": "Spg7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALLLLRGLRPGPEPRPRRLWGLLSGRGPGLSSGAGARRPYAARGTPVGPAAAGGHAPQSLLLRILTPSFEGISGLLLKQHIVPNAVRLWPLSGSTLYFNTSRMKQKNKDNDKPKGKTPEDDEEEKRRKEREDQMYRERLRTLFIIALVMSLLNSLSTSGGSISWADFVNEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESKDRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKERQASGEEEAPAP", "length": 781 }, "evidence": [ { "id": "R4GI64", "url": "https://omabrowser.org/oma/group/R4GI64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TT47-1", "protein_name": "Mitochondrial inner membrane m-AAA protease component paraplegin", "gene_name": "Spg7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAALLLLRALRQSPEPGPWRLWAQLSGRSPGLFSGAGGRRPYVVRGTPIGLAAAGGHTPQSLLLRILTPSFEGVSGLLLKRHIVPSAIRLWQLSGSTLYFNTSGLKQKNKDDDKPKGKAPEDDEEERRRKEREDQMYRERLRTLFIIAIVMSLLNSLSTSGGSISWADFVNEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESKDRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQLLVEMDGMGTADHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIAYSMVKQFGMAPSIGPVSFPEAQEGLVGIGRRPFSQGLQQMMDHEARLLVARAYRHTEKVLLDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKEKQASGEEEAPAP", "length": 781 }, "evidence": [ { "id": "R4GI64", "url": "https://omabrowser.org/oma/group/R4GI64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UQ90-1", "protein_name": "Mitochondrial inner membrane m-AAA protease component paraplegin", "gene_name": "SPG7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRALQSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK", "length": 795 }, "evidence": [ { "id": "R4GI64", "url": "https://omabrowser.org/oma/group/R4GI64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4W8-1", "protein_name": "3.4.24.-", "gene_name": "Spg7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKGLRHVRNALQRGGSQLIQLRSATGQPPRIGRELSLLQLSRRQVMQLQAEYKAIVGLIARSLQLTPKEVRLMHLRSLSSTAKPPTASDGKTEKHEQPEKGSAKAKDDSSKEKKSAVAAEDGDKSSRAAGEEAASTPTSSSTIGEPGEDPNKNSNENDEKMRSVLTKAVLWLFTIYMFVAFFSLLITPRSERPEGSTRYVSWNEFVHHMLAVGEVKELIIRPDMEMVTIILHEGAVIKGRKVSSTIFHMAVADANKFEEKLRDVEKRLGIKDGVPVTYDRQTDTTGRILMLLLVCALLMSIATRMKSIKSPLSMDSFNQMGRAKFTLVDPFDGGRGVLFRDVAGLSEAKQEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVKLESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLVGGTEKRSHALSLAERKVIAYHESGHALVGWMLPNSDILLKVTIVPRTSLALGFAQYTPSEQHLYSKEELFDKMCMALGGRAAENLVFNRITTGAQNDLEKVTKIAYSQIKKFGMNDTLGPIYVRDADETEGGGAMGSGGKKPFSRAMESMIDNEARHVVASAYQTTEGILTTHRDKLEKLAEALLEKETLDYDQVVQLIGPPPYDLGKRQVESVEFEQSLKNLSTDTDATKA", "length": 819 }, "evidence": [ { "id": "R4GI64", "url": "https://omabrowser.org/oma/group/R4GI64/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "ATP-dependent peptidase activity", "id": "GO:0004176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004176", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization involved in programmed cell death", "id": "GO:1902686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902686", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "mitochondrial protein processing", "id": "GO:0034982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034982", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "regulation of calcium import into the mitochondrion", "id": "GO:0110097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110097", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "m-AAA complex", "id": "GO:0005745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005745", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" }, { "name": "mitochondrial permeability transition pore complex", "id": "GO:0005757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005757", "evidence": [ { "database": "UniProtKB", "id": "R4GI64", "url": "https://www.uniprot.org/uniprotkb/R4GI64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GI64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 768, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GI64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GI64" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI64" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 454, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6UZI0-1", "uniprot_ac": "F6UZI0", "uniprot_id": "F6UZI0_CHICK", "mass": { "chemical_mass": 48737.0, "monoisotopic_mass": 48737.0 }, "refseq": {}, "gene_names": [ { "name": "CPA1", "type": "recommended", "evidence": [ { "id": "F6UZI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ] } ], "protein_names": [ { "name": "Carboxypeptidase A1", "type": "recommended", "evidence": [ { "id": "F6UZI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UZI0/entry#names_and_taxonomy" } ] }, { "name": "3.4.17.1", "type": "synonym", "evidence": [ { "id": "F6UZI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UZI0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPA1", "url": "https://www.uniprot.org/uniprotkb/F6UZI0", "locus": { "chromosome": "1", "start_pos": 1507277, "end_pos": 1503030, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006574", "url": "https://www.ensembl.org/id/ENSGALG00010006574" } ] } } ], "crossref": [ { "id": "F6UZI0", "url": "https://alphafold.ebi.ac.uk/entry/F6UZI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVS4", "url": "https://www.orthodb.org/?gene=A0A8V0XVS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6UZI0", "url": "https://www.orthodb.org/?gene=F6UZI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0XVS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6UZI0-1", "url": "https://www.uniprot.org/uniprotkb/F6UZI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGAVKTLDTSIQLEMRALLLLAALGAVAAATTENFVGHQVLRIVPSSDAELQKVQELQELEHLQLDFWLSPRGLGNPVDIRVPFPSLQPVKAHLEANGVPYSIMIEDVQALVDLEQMQMLRRRRFVPLSTSTFDYTSYHTLEEIYAFMDLLVAENPNLVSKLEIGRTTENRPIYVLKFSKGGTNRPAIWIDTGIHSREWVTQASGIWFAKKIVQEQDEGLANILDQMDIFLEIVTNPDGFAFTHTSNRMWRKTRSKRSGSLCVGVDPNRNWDAGFGGSGASSNPCSETYHGPYANSEPEVKAIVDFVKSHKNIKAFISIHSYSQLLLYPYGYTTTAVPDKEELHQVAKEAVAALSSLYGTNYKYGSIITTIYQASGGTIDWTYNQGIKYSFTFELRDTGRYGFLLPASQIVPTAQETWKALEVIMAHTRGHLY", "length": 435, "header": "tr|F6UZI0-1|F6UZI0_CHICK Isoform 1 of Carboxypeptidase A1 OS=Gallus gallus OX=9031 GN=CPA1 PE=3 SV=1 CANONICAL=F6UZI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XVS4-1", "url": "https://www.uniprot.org/uniprotkb/F6UZI0/entry#A0A8V0XVS4-1", "sequence": { "sequence": "MRALLLLAALGAVAAATTENFVGHQVLRIVPSSDAELQKVQELQELEHLQLDFWLSPRGLGNPVDIRVPFPSLQPVKAHLEANGVPYSIMIEDVQALVDLEQMQMLRRRRFVPLSTSTFDYTSYHTLEEIYAFMDLLVAENPNLVSKLEIGRTTENRPIYVLKFSKGGTNRPAIWIDTGIHSREWVTQASGIWFAKKNRMWRKTRSKRSGSLCVGVDPNRNWDAGFGGSGASSNPCSETYHGPYANSEPEVKAIVDFVKSHKNIKAFISIHSYSQLLLYPYGYTTTAVPDKEELHQVAKEAVAALSSLYGTNYKYGSIITTIYQASGGTIDWTYNQGIKYSFTFELRDTGRYGFLLPASQIVPTAQETWKALEVIMAHTRGHLY", "length": 384, "header": "tr|A0A8V0XVS4-1|F6UZI0_CHICK Computationally mapped isoform of Carboxypeptidase A1 OS=Gallus gallus OX=9031 GN=CPA1 PE=3 SV=1 CANONICAL=F6UZI0-1" }, "locus": { "chromosome": "1", "start_pos": 1507017, "end_pos": 1503331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015666.1", "url": "https://www.ensembl.org/id/ENSGALT00010015666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009103.1", "url": "https://www.ensembl.org/id/ENSGALP00010009103.1" } ] } }, { "isoform_ac": "F6UZI0-1", "url": "https://www.uniprot.org/uniprotkb/F6UZI0/entry#F6UZI0-1", "sequence": { "sequence": "MSRGAVKTLDTSIQLEMRALLLLAALGAVAAATTENFVGHQVLRIVPSSDAELQKVQELQELEHLQLDFWLSPRGLGNPVDIRVPFPSLQPVKAHLEANGVPYSIMIEDVQALVDLEQMQMLRRRRFVPLSTSTFDYTSYHTLEEIYAFMDLLVAENPNLVSKLEIGRTTENRPIYVLKFSKGGTNRPAIWIDTGIHSREWVTQASGIWFAKKIVQEQDEGLANILDQMDIFLEIVTNPDGFAFTHTSNRMWRKTRSKRSGSLCVGVDPNRNWDAGFGGSGASSNPCSETYHGPYANSEPEVKAIVDFVKSHKNIKAFISIHSYSQLLLYPYGYTTTAVPDKEELHQVAKEAVAALSSLYGTNYKYGSIITTIYQASGGTIDWTYNQGIKYSFTFELRDTGRYGFLLPASQIVPTAQETWKALEVIMAHTRGHLY", "length": 435, "header": "tr|F6UZI0-1|F6UZI0_CHICK Isoform 1 of Carboxypeptidase A1 OS=Gallus gallus OX=9031 GN=CPA1 PE=3 SV=1 CANONICAL=F6UZI0-1" }, "locus": { "chromosome": "1", "start_pos": 1507017, "end_pos": 1503283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015669.1", "url": "https://www.ensembl.org/id/ENSGALT00010015669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009106.1", "url": "https://www.ensembl.org/id/ENSGALP00010009106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "F6UZI0", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6UZI0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 435, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6UZI0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6UZI0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6UZI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UZI0" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 430, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.17.1", "ec_name": "Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.", "evidence": [ { "id": "3.4.17.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.17.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P531-1", "uniprot_ac": "F1P531", "uniprot_id": "F1P531_CHICK", "mass": { "chemical_mass": 60679.0, "monoisotopic_mass": 60679.0 }, "refseq": { "ac": "XP_424967", "name": "methylcrotonoyl-CoA carboxylase beta chain, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424967" }, "gene_names": [ { "name": "MCCC2", "type": "recommended", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ] }, { "name": "MCCC2", "type": "synonym", "evidence": [ { "id": "XP_424967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424967" } ] } ], "protein_names": [ { "name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA carboxylase 2", "type": "synonym", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit", "type": "synonym", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta", "type": "synonym", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#names_and_taxonomy" } ] }, { "name": "6.4.1.4", "type": "synonym", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#names_and_taxonomy" } ] }, { "name": "methylcrotonoyl-CoA carboxylase beta chain, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424967" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_424967.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424967" } ] }, { "annotation": "Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531#function" }, { "database": "UniProtKB", "id": "ARBA00053988", "url": "https://www.uniprot.org/uniprotkb/ARBA00053988#function" }, { "database": "UniProtKB", "id": "A0A8V0Y920", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y920#function" }, { "database": "UniProtKB", "id": "A0A8V0XW50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW50#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCCC2", "url": "https://www.uniprot.org/uniprotkb/F1P531", "locus": { "chromosome": "Z", "start_pos": 73669974, "end_pos": 73633866, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009143", "url": "https://www.ensembl.org/id/ENSGALG00010009143" } ] } } ], "crossref": [ { "id": "F1P531", "url": "https://alphafold.ebi.ac.uk/entry/F1P531", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002529", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427395", "url": "https://www.ncbi.nlm.nih.gov/gene/427395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427395", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427395", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GATTHCE", "url": "https://omabrowser.org/oma/group/GATTHCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XW50", "url": "https://www.orthodb.org/?gene=A0A8V0XW50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y920", "url": "https://www.orthodb.org/?gene=A0A8V0Y920", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P531", "url": "https://www.orthodb.org/?gene=F1P531", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22855:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22855:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196780", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13589", "url": "https://www.rhea-db.org/rhea/13589", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XW50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y920", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y920", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y920-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y920-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P531-1", "url": "https://www.uniprot.org/uniprotkb/F1P531-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLGRCRLLFRAGAARPARACYGEAAAVGSRPDAGSPLYQENYERMKALVTQLQEQAEKIRLGGGEKARKLHTSRGKLLPRERIDRLIDPGSPFLEFSQFAGYQLYGNEEVPAGGIITGIGRISGVECLIVANDATVKGGTYYPITVKKHLRAQEIAMQNHLPCIYLVDSGGANLPRQAEVFPDRDHFGRIFYNQAIMSSQGIPQIAVVMGSCTAGGAYVPAMADESIIVGKQGTIFLGGPPLVKAATGEEVSAEDLGGADLHCRHSGVTDHYALDDSHALHLARKTVRSLNLQKKVDVSIEPSEEPLFPADEIYGIVGDQLKRNFDVKEVIARIVDGSKFDEFKALYGDTLITGFARIFGYLVGIIGNNGVLFSESAKKGTHFIQLCCQRNIPIVFLQNITGFMVGREYEAGGIAKDGAKMVTAVACASVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATIAKDQKAREGKQLSKADEEALKEPIIRRFEEEGNPYYSSARLWDDGIIDPADTRLVLGLSLSAALNAPTKKTEFGVFRM", "length": 560, "header": "tr|F1P531-1|F1P531_CHICK Isoform 1 of Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC2 PE=1 SV=4 CANONICAL=F1P531-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XW50-1", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#A0A8V0XW50-1", "sequence": { "sequence": "MRAELDVSYHGDRVVHCLILMENYERMKALVTQLQEQAEKIRLGGGEKARKLHTSRGKLLPRERIDRLIDPGSPFLEFSQFAGYQLYGNEEVPAGGIITGIGRISGVECLIVANDATVKGGTYYPITVKKHLRAQEIAMQNHLPCIYLVDSGGANLPRQAEVFPDRDHFGRIFYNQAIMSSQGIPQIAVVMGSCTAGGAYVPAMADESIIVGKQGTIFLGGPPLVKAATGEEVSAEDLGGADLHCRHSGVTDHYALDDSHALHLARKTVRSLNLQKKVDVSIEPSEEPLFPADEIYGIVGDQLKRNFDVKEVIARIVDGSKFDEFKALYGDTLITGFARIFGYLVGIIGNNGVLFSESAKKGTHFIQLCCQRNIPIVFLQNITGFMVGREYEAGGIAKDGAKMVTAVACASVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATIAKDQKAREGKQLSKADEEALKEPIIRRFEEEGNPYYSSARLWDDGIIDPADTRLVLGLSLSAALNAPTKKTEFGVFRM", "length": 541, "header": "tr|A0A8V0XW50-1|F1P531_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC2 PE=1 SV=1 CANONICAL=F1P531-1" }, "locus": { "chromosome": "Z", "start_pos": 73669632, "end_pos": 73634562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021813.1", "url": "https://www.ensembl.org/id/ENSGALT00010021813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012479.1", "url": "https://www.ensembl.org/id/ENSGALP00010012479.1" } ] } }, { "isoform_ac": "A0A8V0Y920-1", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#A0A8V0Y920-1", "sequence": { "sequence": "MARRRRWARGPTRALRSTRSFICWHRRHSSISENYERMKALVTQLQEQAEKIRLGGGEKARKLHTSRGKLLPRERIDRLIDPGSPFLEFSQFAGYQLYGNEEVPAGGIITGIGRISGVECLIVANDATVKGGTYYPITVKKHLRAQEIAMQNHLPCIYLVDSGGANLPRQAEVFPDRDHFGRIFYNQAIMSSQGIPQIAVVMGSCTAGGAYVPAMADESIIVGKQGTIFLGGPPLVKAATGEEVSAEDLGGADLHCRHSGVTDHYALDDSHALHLARKTVRSLNLQKKVDVSIEPSEEPLFPADEIYGIVGDQLKRNFDVKEVIARIVDGSKFDEFKALYGDTLITGFARIFGYLVGIIGNNGVLFSESAKKGTHFIQLCCQRNIPIVFLQNITGFMVGREYEAGGIAKDGAKMVTAVACASVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATIAKDQKAREGKQLSKADEEALKEPIIRRFEEEGNPYYSSARLWDDGIIDPADTRLVLGLSLSAALNAPTKKTEFGVFRM", "length": 552, "header": "tr|A0A8V0Y920-1|F1P531_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC2 PE=1 SV=1 CANONICAL=F1P531-1" }, "locus": { "chromosome": "Z", "start_pos": 73669632, "end_pos": 73633973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021816.1", "url": "https://www.ensembl.org/id/ENSGALT00010021816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012480.1", "url": "https://www.ensembl.org/id/ENSGALP00010012480.1" } ] } }, { "isoform_ac": "F1P531-1", "url": "https://www.uniprot.org/uniprotkb/F1P531/entry#F1P531-1", "sequence": { "sequence": "MLLGRCRLLFRAGAARPARACYGEAAAVGSRPDAGSPLYQENYERMKALVTQLQEQAEKIRLGGGEKARKLHTSRGKLLPRERIDRLIDPGSPFLEFSQFAGYQLYGNEEVPAGGIITGIGRISGVECLIVANDATVKGGTYYPITVKKHLRAQEIAMQNHLPCIYLVDSGGANLPRQAEVFPDRDHFGRIFYNQAIMSSQGIPQIAVVMGSCTAGGAYVPAMADESIIVGKQGTIFLGGPPLVKAATGEEVSAEDLGGADLHCRHSGVTDHYALDDSHALHLARKTVRSLNLQKKVDVSIEPSEEPLFPADEIYGIVGDQLKRNFDVKEVIARIVDGSKFDEFKALYGDTLITGFARIFGYLVGIIGNNGVLFSESAKKGTHFIQLCCQRNIPIVFLQNITGFMVGREYEAGGIAKDGAKMVTAVACASVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATIAKDQKAREGKQLSKADEEALKEPIIRRFEEEGNPYYSSARLWDDGIIDPADTRLVLGLSLSAALNAPTKKTEFGVFRM", "length": 560, "header": "tr|F1P531-1|F1P531_CHICK Isoform 1 of Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC2 PE=1 SV=4 CANONICAL=F1P531-1" }, "locus": { "chromosome": "Z", "start_pos": 73669632, "end_pos": 73633909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021819.1", "url": "https://www.ensembl.org/id/ENSGALT00010021819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012481.1", "url": "https://www.ensembl.org/id/ENSGALP00010012481.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427395", "resource": "KEGG Pathway" }, { "id": "R-GGA-196780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "resource": "Reactome", "description": "Biotin transport and metabolism" }, { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HIT4-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "Mccc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWSALRAALRPSAPAAVSRSRAYHGDSVARLGTQPDSGSSTYQENYEQMKALVSQLHERAQYVRLGGSEKARARHTSRGKLLPRDRIDNLLDPGSPFLEFSQFAGYQLYGDEEVPAGGIITGIGRVSGVECMIVANDATVKGGTYYPVTVKKHIRAQEIALQNRLPCIYLVDSGGANLPRQADTFPDRDHFGRIFYNQAIMSSKNITQIAVVMGSCTAGGAYVPAMADENIIVQKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVTDHYALDDHHALHLTRKVVRSLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFNEFKALYGDTLVTGFARIFGYPVGIIGNNGVLFSESAKKGAHFVQLCCQRKIPLLFLQNITGFMVGRDYEAEGIAKDGAKMVAAVSCAKVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATVARDQKAREGKQFSSAEEAALKEPIIKRFEEEGNPYYSSARLWDDGIIDPVDTRLVLGLSISAALNAPIQKTDFGIFRM", "length": 563 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ULD5-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "Mccc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGALRSALRPCCRAAVPPQRAYHGDSVARLGTQPDSASSTYQENYEQMKALVSQLHERAQYVRLGGSEKARARHTSRGKLLPRDRIDNLIDPGSPFLEFSQFAGYQLYGDEEVPAGGIITGIGRVSGVECMIVANDATVKGGTYYPVTVKKHVRAQEIALQNRLPCIYLVDSGGANLPRQADTFPDRDHFGRIFYNQAIMSSKNITQIAVVMGSCTAGGAYVPAMADENIIVQKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVTDHYALDDHHALHLTRKVVRSLNYQKKMDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFNEFKALYGDTLVTGFARIFGYPVGIIGNNGVLFSESAKKGAHFVQLCCQRNIPLLFLQNITGFMVGRDYEAEGIAKDGAKMVAAVACAKVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATVARDQKAREGKQFSSAEEAALKEPIIKRFEEEGNPYYSSARLWDDGIIDPVDTRLVLGLSLSAALNAPIQRTDFGIFRM", "length": 563 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIT9-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "Mccc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWGALRSVLRPCSRASVPRQRAYHGDAVARLGTQPDSGSSTYQENYEQMKALVNQLHERAQYVRLGGSEKARARHTSRGKLLPRDRIDNLIDPGSPFLEFSQFAGYKLYGEEEVPAGGIITGIGRVSGVECMIVANDATVKGGTYYPVTVKKHVRAQEIALQNRLPCIYLVDSGGANLPRQADTFPDRDHFGRIFYNQAIMSSKNITQIAVVMGSCTAGGAYVPAMADENIIVQRQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRRSGVTDHYALDDHHALHLTRKVVRSLNYQKKLDVTVEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFNEFKALYGDTLVTGFARIFGYPVGIIGNNGVLFSESAKKGAHFVQLCCQRNIPLLFLQNITGFMVGKDYEAEGIAKDGAKMVAAVSCAKVPKITVIIGGSYGAGNYGMCGRAYSPRFLYMWPNARISVMGGEQAATVLATVARDQRAREGKQFSSAEEAALKEPIIKRFEEEGNPYYSSARLWDDGIIDPVDTRLVLGLSISAALNAPIQRTDFGIFRM", "length": 563 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8T2J9-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "mccb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKSISLLKNNQILLKNIINNGRIINNVGEKLSSKSLLKINYSSSTTDRTFNILDGTIDKNSAEYKDNLINMNSTLKQLKENIEKIKLGGGEKLNQKNISRGKLLVRERIEALIDVGSPFLEFSQLAGWGMYGKEEVAAGGIITGIGKIHGVECVIVANDSTVKGGTYFPITVKKHLRAQEIAQENNLPCIYLVDSGGANLPRQADVFPDRDHFGRIFFNQANMSAKRIPQIAVVMGSCTAGGAYVPAMADESVIVKGTGTIFLGGPPLVKAATGEIVTSEELGGADLHCRTSGVTDHYARDDAEAIAITRRIVSNLNRKKQPSPVITETEEPLYPTSELAGIVPSDLKKNFDIRKVIARLVDGSRFDEFKELYGTTLICGFARVHGMPVGIIANNGILFSESAVKGAHFIELCNQRGIPLVFLQNITGFMVGKTYESKGIAKDGAKMVMAVATAKVPKITMIIGGSFGAGNYGMCGRSYSPRFLYMWPNAKISVMGGEQAASVLAQIQKDNMAKENKQWSPEEENTFKKPISDKFEEEGSIYYSSARCWDDGVIDPQDSRKVIALSLSACMNQPINPPSDGFGVFRM", "length": 588 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9HCC0-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "MCCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIEKTDFGIFRM", "length": 563 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LDD8-1", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "MCCB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLRILGRRVVSASKELTSIQQWRIRPGTDSRPDPFRTFRGLQKGFCVGILPDGVDRNSEAFSSNSIAMEGILSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYEEPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCIYLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMADESVMVKGNGTIFLAGPPLVKAATGEEVSAEDLGGATVHCTVSGVSDYFAQDELHGLAIGRNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQQFDVRSIIARIVDGSEFDEFKKQYGTTLVTGFARIYGQTVGIIGNNGILFNESALKGAHFIELCSQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKITIITGASFGAGNYAMCGRAYSPDFMFIWPNARIGIMGGAQAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVDAYEREANPYYSTARLWDDGVIDPCDTRKVLGLCLSAALNRPLEDTRFGVFRM", "length": 587 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V9A7-1", "protein_name": "Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "Mccc2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRLNWLFRSSSVLLRSQVRLLHVGDANVLHSEVDKQSAEYKENAREMASLVGDLRNFTSQVLKGGGQKAIERHTSRGKLLARERINLLLDKGSPFLELSALAGHELYGEEVVNSGGIVTGVGRVCGTECLVVANDATVKGGSYYPITVKKHLRAQEIAQENRLPCIYLVDSGGANLPRQADVFPDKLHFGRIFYNQANMSAQGIPQIAVVMGSCTAGGAYVPAMADESIIVKKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCKTSGVTDHYALDDEHALYLARQIVSNLNLSATNSYNDQLMHSSQVNFQTATPPSAVEEPRYDAEELYGIVGPNLTKSFDVREVIARIVDGSRFTEFKKLYGETLVCGFAKLYGHTVGIVGNNGVLFSESALKGAHFIQLCAQRKIPLVFLQNITGFMVGRDAEANGIAKNGAKMVTAVACANVPKFTVIIGGSYGAGNYGMCGRAYSPRFLYMWPNSRISVMGGTQAANVMAQITEDQRKRAGKEFSEEEAQKLKAPIVEMFEAEGSPYYSTARLWDDGIIDPANTRQILGLSLKAALNNAGQETKFGVFRM", "length": 578 }, "evidence": [ { "id": "F1P531", "url": "https://omabrowser.org/oma/group/F1P531/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "methylcrotonoyl-CoA carboxylase activity", "id": "GO:0004485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004485", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "pmid": "" }, { "name": "methylcrotonoyl-CoA carboxylase complex", "id": "GO:1905202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905202", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "F1P531", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13589", "name": "", "equation": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P531-1", "A0A8V0ZWN0-1", "A0A8V0YPR9-1" ], "evidence": [ { "id": "13589", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13589" } ] }, { "id": "R-GGA-2993799", "name": "HLCS biotinylates 6xMCCC1:6xMCCC2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-2993799", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2993799" } ] }, { "id": "R-GGA-3323111", "name": "Cytosolic carboxylases translocate to mitochondrial matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XS41-1", "A0A8V0YPR9-1", "A0A8V0ZX51-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-3323111", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3323111" } ] }, { "id": "R-GGA-508308", "name": "beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113548", "R-ALL-70772" ], "output_participant_list": [ "R-ALL-29896", "R-ALL-70744" ], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-508308", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-508308" } ] }, { "id": "R-GGA-70773", "name": "beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-70773", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70773" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113548", "participant_name": "Pi [mitochondrial matrix]", "crossref": [ { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29896", "participant_name": "HCO3- [mitochondrial matrix]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-70744", "participant_name": "bMC-CoA [mitochondrial matrix]", "crossref": [ { "id": "C03069", "database": "COMPOUND", "url": "" }, { "id": "57344", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551513", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-70772", "participant_name": "bMG-CoA [mitochondrial matrix]", "crossref": [ { "id": "57346", "database": "ChEBI", "url": "" }, { "id": "ZINC000096077648", "database": "ZINC", "url": "" }, { "id": "C03231", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XS41", "gene_name": "PCCA", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XS41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS41" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XS41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS41" } ] } ] }, { "uniprot_ac": "A0A8V0YPR9", "gene_name": "MCCC1", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWN0", "gene_name": "MCCC2L", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWN0" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "A0A8V0ZWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZX51", "gene_name": "PCCB", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZX51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX51" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "A0A8V0ZX51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX51" } ] } ] }, { "uniprot_ac": "F1P531", "gene_name": "MCCC2", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ] } ] } ], "biomarkers": [], 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The reference sequence was derived from JAENSK010000006.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264280" } ] }, { "annotation": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. 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"database": "Ensembl Gene", "id": "ENSGALG00010006901", "url": "https://www.ensembl.org/id/ENSGALG00010006901" } ] } } ], "crossref": [ { "id": "F1P5B0", "url": "https://alphafold.ebi.ac.uk/entry/F1P5B0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008444", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008444", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02186", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02186", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416694", "url": "https://www.ncbi.nlm.nih.gov/gene/416694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { 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"Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 387, "end_pos": 389 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SAHNYCE", "url": "https://omabrowser.org/oma/group/SAHNYCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A167", "url": "https://www.orthodb.org/?gene=A0A8V1A167", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8P9", "url": "https://www.orthodb.org/?gene=A0A8V1A8P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ9", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GIW1", "url": "https://www.orthodb.org/?gene=R4GIW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46469", "url": 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Computationally mapped isoform of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=3 SV=1 CANONICAL=R4GIW1-1" }, "locus": { "chromosome": "26", "start_pos": 5115968, "end_pos": 5111271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064756.1", "url": "https://www.ensembl.org/id/ENSGALT00010064756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039607.1", "url": "https://www.ensembl.org/id/ENSGALP00010039607.1" } ] } }, { "isoform_ac": "A0A8V1A8P9-1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1/entry#A0A8V1A8P9-1", "sequence": { "sequence": "MDVNISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 243, "header": "tr|A0A8V1A8P9-1|R4GIW1_CHICK Computationally mapped isoform of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=3 SV=1 CANONICAL=R4GIW1-1" }, "locus": { "chromosome": "26", "start_pos": 5115968, "end_pos": 5111267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064740.1", "url": "https://www.ensembl.org/id/ENSGALT00010064740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039601.1", "url": "https://www.ensembl.org/id/ENSGALP00010039601.1" } ] } }, { "isoform_ac": "A0A8V1ABJ9-1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1/entry#A0A8V1ABJ9-1", "sequence": { "sequence": "MRIALYGSKMADTAPGGSGTRSGSKHTTTPADNYYLARRRTLQVVVSSLLTEAGFESAEKAAVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDLKKRMLQYYSRTPPCLAAGMGRRI", "length": 290, "header": "tr|A0A8V1ABJ9-1|R4GIW1_CHICK Computationally mapped isoform of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=3 SV=1 CANONICAL=R4GIW1-1" }, "locus": { "chromosome": "26", "start_pos": 5115912, "end_pos": 5110341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064752.1", "url": "https://www.ensembl.org/id/ENSGALT00010064752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039605.1", "url": "https://www.ensembl.org/id/ENSGALP00010039605.1" } ] } }, { "isoform_ac": "R4GIW1-1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1/entry#R4GIW1-1", "sequence": { "sequence": "MRIALYGSKMADTAPGGSGTRSGSKHTTTPADNYYLARRRTLQVVVSSLLTEAGFESAEKAAVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 312, "header": "tr|R4GIW1-1|R4GIW1_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 8 OS=Gallus gallus OX=9031 GN=TAF8 PE=3 SV=2 CANONICAL=R4GIW1-1" }, "locus": { "chromosome": "26", "start_pos": 5115968, "end_pos": 5110341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064747.1", "url": "https://www.ensembl.org/id/ENSGALT00010064747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039603.1", "url": "https://www.ensembl.org/id/ENSGALP00010039603.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-GGA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-GGA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-GGA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "A7MAZ4-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADAAATAGAAGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEMQQMEETDSSEQDEQTDTENLPLHISPDDSGAEKENTSVLQQNPSLSGSRNGEESIIDNPYLRPVKKPKIRRKKSLS", "length": 310 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZY89-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTELFYKAGPQAPPFATSPPHNYKSRRALRSRTLRESKMADTATGPGGSGTRPGNKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQDEQTDTENIALHISTDESGAEKENTSVLQQNSSLSGSRNGEESTIDNPYLRPVKKPKIRRKKLTRKRVLESLTISFHSPSCRSRERNQPAGAALSWTLPTLETRARYFPSWCSWFSPLQFACVIVPSLSEVVLFNCEQTIYVFSTELERQKKI", "length": 435 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HR49-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADTAAGPGGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQDEQTDTENIALHISTGDSGAEKENASVLQQNSSLSGSRNGEENVIDNPYLRPVKKPKIRRKKSLS", "length": 308 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5ZMS1-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVETLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNKPHPSHIPGYFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTVPYLTALLPSELEMQQMEETDSSEQDDQTDTENLPLHISTDDSGPEKENASVLQQNTSLSGSRNGEENMIDNPYLRPVKKPKIRRKK", "length": 244 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6P0T2-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "taf8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADSVMMGSGSLNSGSRSGSSKTCTSPTENYQLARRRTLQVVVSALLTECGFDSAEKAVVETLTEMMQSYITEVGRCAKANCEHTARSTPTLSDVVITLVEMGFNVDTLPVYAKRSQRMVITAPPITNAPVVPKSLTAGQKRTHPAHIPSHFPDFPDPHTYIRTPTFREPVSDYQVVREKAASQRRDVERALTRFMAKTGETQSLFKDDISAFPLIAAKPSPIPYLSALLPSELELQSLEETDSSEQDDQMDNDNNTSHIMQDDSGADKENEVLPPGGVVPSGKANEENMIDNPYLRPVKKPKVRRKK", "length": 308 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z7C8-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "TAF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADAAATAGAGGSGTRSGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEMQQMEETDSSEQDEQTDTENLALHISMEDSGAEKENTSVLQQNPSLSGSRNGEENIIDNPYLRPVKKPKIRRKKSLS", "length": 310 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQH4-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTAAGPGGSGTRPGSKQSTNPADNYHLARRRTLQVVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFNVDTLPAYAKRSQRMVITAPPVTNQPVTPKALTAGQNRPHPPHIPSHFPEFPDPHTYIKTPTYREPVSDYQILREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTIPYLTALLPSELEIQQMEETDSSEQEEQTDTENNALHISTDDSGAEKESASVLQQSSSLSGSRNGEESVIDNPYLRPVKKPKIRRKKSLS", "length": 308 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWY6-1", "protein_name": "Transcription initiation factor TFIID subunit 8", "gene_name": "Taf8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKVEAVTVSNVDPYRRILNKVVSQLLLDKGAGQASNHSLETLTQMLQALIWEIGNSAHNYCELSGRTMPTVGDVSLALINMGISISNLDPYMRKETHVPIPLPPQQTQQRPLSLLQAGIKAPHPHYVPSYFPPMPDPHAYIRTPTHKQPVTEYEAIREKAACQKRDIEKALTKFLCKTTETNNLFPTEDNMFPLIACKPAFPPYAAALNPTDQVFDFEELEYHYLVANRTEDEPSKDDGEEGDSENEEMDGDKSKEEKPELDIKPNSNTNKAILENPNIDNPYLRAATLPKRSKNCPTPGTMPSRSLATTAPTIRTPSTLEITKTNL", "length": 328 }, "evidence": [ { "id": "R4GIW1", "url": "https://omabrowser.org/oma/group/R4GIW1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "R4GIW1", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GIW1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GIW1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GIW1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIW1" }, { "id": "SM00576", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00576" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromodomain associated", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 111, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "H9L3L2-1", "uniprot_ac": "H9L3L2", "uniprot_id": "H9L3L2_CHICK", "mass": { "chemical_mass": 138522.0, "monoisotopic_mass": 138522.0 }, "refseq": { "ac": "NP_001026576", "name": "coatomer subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026576" }, "gene_names": [ { "name": "COPA", "type": "recommended", "evidence": [ { "id": "H9L3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L3L2" } ] }, { "name": "COPA", "type": "synonym", "evidence": [ { "id": "NP_001026576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026576" } ] } ], "protein_names": [ { "name": "Coatomer subunit alpha", "type": "recommended", "evidence": [ { "id": "H9L3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#names_and_taxonomy" } ] }, { "name": "coatomer subunit alpha", "type": "synonym", "evidence": [ { "id": "NP_001026576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026576" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851796.1, SRR13267655.108897.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000349.1. On Sep 23, 2021 this sequence version replaced NP_001026576.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026576" } ] }, { "annotation": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W4#function" }, { "database": "UniProtKB", "id": "ARBA00024791", "url": "https://www.uniprot.org/uniprotkb/ARBA00024791#function" }, { "database": "UniProtKB", "id": "A0A8V1AF94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF94#function" }, { "database": "UniProtKB", "id": "A0A8V1AH90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH90#function" }, { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2#function" } ] }, { "annotation": "Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W4#function" }, { "database": "UniProtKB", "id": "ARBA00057585", "url": "https://www.uniprot.org/uniprotkb/ARBA00057585#function" }, { "database": "UniProtKB", "id": "A0A8V1AF94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF94#function" }, { "database": "UniProtKB", "id": "A0A8V1AH90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH90#function" }, { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COPA", "url": "https://www.uniprot.org/uniprotkb/H9L3L2", "locus": { "chromosome": "25", "start_pos": 1275987, "end_pos": 1204515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027663", "url": "https://www.ensembl.org/id/ENSGALG00010027663" } ] } } ], "crossref": [ { "id": "H9L3L2", "url": "https://alphafold.ebi.ac.uk/entry/H9L3L2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009153", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426906", "url": "https://www.ncbi.nlm.nih.gov/gene/426906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426906", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMTYQKQ", "url": "https://omabrowser.org/oma/group/EMTYQKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9W4", "url": "https://www.orthodb.org/?gene=A0A8V1A9W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF89", "url": "https://www.orthodb.org/?gene=A0A8V1AF89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF94", "url": "https://www.orthodb.org/?gene=A0A8V1AF94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH90", "url": "https://www.orthodb.org/?gene=A0A8V1AH90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "H9L3L2", "url": "https://www.orthodb.org/?gene=H9L3L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19876:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19876:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3L2-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIMICNRKLESLCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDRLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVAERVRILRNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPVMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDNVGTEGWGEDAELQLDEDGFVDAGEGFGEEGLGKGQEEGGGWEVEEDLDLPPELDVPAGPAGGAEDGFFVPPTKGTSPAQVWCNNSQLPVDHILAGSFETAMRLLHDQVGVTNFGPYKQLFLQTYARGRTTYQALPCLPTMYGYPHRNWKEAGLKNALPAVGLKLNDLIQRLQLCYQLTTAGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLIAICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224, "header": "tr|H9L3L2-1|H9L3L2_CHICK Isoform 1 of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=2 CANONICAL=H9L3L2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9W4-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#A0A8V1A9W4-1", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIMICNRKLESLCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDRLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVAERVRILRNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPVMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDNVGTEGWGEDAELQLDEDGFVDAGEGFGEEEGGGWEVEEDLDLPPELDVPAGPAGGAEDGFFVPPTKGTSPAQVWCNNSQLPVDHILAGSFETAMRLLHDQVGVTNFGPYKQLFLQTYARGRTTYQALPCLPTMYGYPHRNWKEAGLKNALPAVGLKLNDLIQRLQLCYQLTTAGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLIAICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1217, "header": "tr|A0A8V1A9W4-1|H9L3L2_CHICK Computationally mapped isoform of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=1 CANONICAL=H9L3L2-1" }, "locus": { "chromosome": "25", "start_pos": 1275314, "end_pos": 1257574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067066.1", "url": "https://www.ensembl.org/id/ENSGALT00010067066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040996.1", "url": "https://www.ensembl.org/id/ENSGALP00010040996.1" } ] } }, { "isoform_ac": "A0A8V1AF89-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#A0A8V1AF89-1", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 640, "header": "tr|A0A8V1AF89-1|H9L3L2_CHICK Computationally mapped isoform of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=1 CANONICAL=H9L3L2-1" }, "locus": { "chromosome": "25", "start_pos": 1275314, "end_pos": 1257574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067051.1", "url": "https://www.ensembl.org/id/ENSGALT00010067051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040987.1", "url": "https://www.ensembl.org/id/ENSGALP00010040987.1" } ] } }, { "isoform_ac": "A0A8V1AF94-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#A0A8V1AF94-1", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIMICNRKLESLCNIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDRLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVAERVRILRNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPVMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDNVGTEGWGEDAELQLDEDGFVDAGEGFGEEGLGKGQEEGGGWEVEEDLDLPPELDVPAGPAGGAEDGFFVPPTKGTSPAQVWCNNSQLPVDHILAGSFETAMRLLHDQVGVTNFGPYKQLFLQTYARGRTTYQALPCLPTMYGYPHRNWKEAGLKNALPAVGLKLNDLIQRLQLCYQLTTAGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLIAICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1206, "header": "tr|A0A8V1AF94-1|H9L3L2_CHICK Computationally mapped isoform of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=1 CANONICAL=H9L3L2-1" }, "locus": { "chromosome": "25", "start_pos": 1275314, "end_pos": 1257574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067058.1", "url": "https://www.ensembl.org/id/ENSGALT00010067058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040992.1", "url": "https://www.ensembl.org/id/ENSGALP00010040992.1" } ] } }, { "isoform_ac": "A0A8V1AH90-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#A0A8V1AH90-1", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIMICNRKLESLCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDRLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVAERVRILRNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPVMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDNVGTEGWGEDAELQLDEDGFVDAGEGFGEEGLGKGQEEGGGWEVEEDLDLPPELDVPAGPAGGAEDGFFVPPTKGTSPAQVWCNNSQLPVDHILAGSFETAMRLLHDQVGVTNFGPYKQLFLQTYARGRTTYQALPCLPTMYGYPHRNWKEAGLKNALPAVGLKLNDLIQRLQLCYQLTTAGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLIAICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVREFLLPLTPT", "length": 1216, "header": "tr|A0A8V1AH90-1|H9L3L2_CHICK Computationally mapped isoform of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=1 CANONICAL=H9L3L2-1" }, "locus": { "chromosome": "25", "start_pos": 1274983, "end_pos": 1257574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067064.1", "url": "https://www.ensembl.org/id/ENSGALT00010067064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040995.1", "url": "https://www.ensembl.org/id/ENSGALP00010040995.1" } ] } }, { "isoform_ac": "H9L3L2-1", "url": "https://www.uniprot.org/uniprotkb/H9L3L2/entry#H9L3L2-1", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLYYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSILIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIMICNRKLESLCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDRLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVAERVRILRNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPVMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDNVGTEGWGEDAELQLDEDGFVDAGEGFGEEGLGKGQEEGGGWEVEEDLDLPPELDVPAGPAGGAEDGFFVPPTKGTSPAQVWCNNSQLPVDHILAGSFETAMRLLHDQVGVTNFGPYKQLFLQTYARGRTTYQALPCLPTMYGYPHRNWKEAGLKNALPAVGLKLNDLIQRLQLCYQLTTAGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLIAICREYIVGLSMEIERKKLPKETLEHQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDTYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYCPEFQGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224, "header": "tr|H9L3L2-1|H9L3L2_CHICK Isoform 1 of Coatomer subunit alpha OS=Gallus gallus OX=9031 GN=COPA PE=1 SV=2 CANONICAL=H9L3L2-1" }, "locus": { "chromosome": "25", "start_pos": 1275314, "end_pos": 1257574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067069.1", "url": "https://www.ensembl.org/id/ENSGALT00010067069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040999.1", "url": "https://www.ensembl.org/id/ENSGALP00010040999.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 554, "start_aa": "Thr", "end_pos": 554, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr554", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426906", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJX8-1", "protein_name": "Coatomer subunit alpha", "gene_name": "COPA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDAESITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLEALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDYGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAENLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDIPPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVTQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGIPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSMEIERKKLPKESLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H7Y0-1", "protein_name": "Coatomer subunit alpha", "gene_name": "Copa", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKIQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEASEGLGEDALGKGQEEGGGWDVEEDLELPPELDIPAGVAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKEAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKESLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLSYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYAPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V6T1-1", "protein_name": "Coatomer subunit alpha", "gene_name": "Copa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LLSSADTRHAYVTKENSLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKIQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDTLGKGQEEGGGWDVEEDLELPPELDVPSGVAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVVQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLSTVGKFEDAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1227 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53621-1", "protein_name": "Coatomer subunit alpha", "gene_name": "COPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53622-1", "protein_name": "Coatomer subunit alpha", "gene_name": "COP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQNQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVNEANGKFALVILPKQPVGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRNIKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVALMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIKTLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNLVGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLIQEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNTFYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDASNFVQRPVISKPLEKWPLKEAELSYFEKAVLGQIDDLTIDDETPAVNTTQEQEEPLGEENFNDEDIGEDEGAWDLGDEDLDVGEELPEEVEQGEITSPAQEVETAIWIKNSKLPAVLVAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYDDTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAEDEKLAHKILETAREYILGLSIELERRSLKEGNTVRMLELAAYFTKAKLSPIHRTNALQVAMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAKFDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV", "length": 1201 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55FR9-1", "protein_name": "Coatomer subunit alpha", "gene_name": "copa", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLYKFETKASRVKGLSFHPTRPWILASLHSGSIHLYDYRIKTLLEKFDEHEGPVRGINFHMTQPLFVSGGDDYKIKVWNYKQRRCLFTLKGHKDYIRSVEFHREAPWIVSSSDDMVIRIWNWQSRTCIAELNGHNHYVMSALFHPKDDLVVSASLDQTIRIWDISGLKKKMTTVKPYRENDPMRLQDELFGTDISVRLSLEGHDRGVNWASFHPTQPYIVSASDDHQVKLWRMNDPIVDTFRGHYNNVSCALFHPRQDLIISNSEDKTIRVWDIIKKSTVHMIRRDHDRFWTLASHPNQNLFAAGHDSGMIVFKLERERPLFVQNGDSGVFFLKKKNFNSFDFQAGRTVSLFHISKLPSNNGTQTMSYNQTERAILVSSDAEGGSYHLYKIPPKDSNTVNTKKGTGVAAIFVGRDRFAVLDKGNNVVIRDLENEEIKRCQIPFTIDWIYPSGSPGTILIQSEDKIHMFDIQQKKMLCEIQVHGVRYVIWSKDRNYVAFLTRDFIVLANKKLEQICMIHETVLPKSGVWDDNGVFIYSTSNHLKYLLQNGDNGTIRTLESTIYITGVKNNKVFAIDREFKNRIIEIDTTEYVLKLSLLQQNYNQVMTILRENRLVGKAIIAYLQKKGYPDVVHFVKDDRTRFNLALDAGNIDIALSSAKILDDKDCWNRLGVEALKQGNYQVVEMAYSRTSEFDRLSFLYLLVGNLSTLKKMISYESSDIMSRFHFSLYLGDVEERIKILQEAGLHQLAYITASIHGLTEKAESIGNLITSDGKSQLPQLPKQSYLLVPPSPINCNPNELNWPLLTTTKSVSDVMGENRFGVEQSTSTPTGDWESDEDIFSEGKSQQQSSQQQQQQQQKGDWEEDILIGDGNNGGGDDGGWERDDLKGLEKIGTDGFNNKQNDHVALFVPPQPGPSFSMIWARNSQFAVDHIAAGSFESAMNILNSQIGAVNFDPIKSMFMNIFMATRSSLGCNASTPSLLMPIQRKSAAPYITYGLGHLIERLKTNAYKSTTEGKFNDALSHFTYILHTIIFCSVDNKQEVNELKDLINICREYILGIKIELQRKELSIGAQKDSTLGRQAELAAYFTHCNLDPSHLILSLRSAMNCAYKVKHFNLAASFARRLISLNPNPDLATQAKKVFNFAQQTPTPSDIQQLNYDERNPFVICAHSYVPIYKGSPLIKCPYCSSCYLPTHKGKVCSVCQISEIGKDVQGLQVITIQK", "length": 1221 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CIE6-1", "protein_name": "Coatomer subunit alpha", "gene_name": "Copa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKIQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLSAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDVLGKGQEEGGGWDVEEDLELPPELDVPSGVSGSAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR", "length": 1224 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94A40-1", "protein_name": "Coatomer subunit alpha-1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLTKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKNHRCLFTLLGHLDYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVSVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNSDLFGGVDAIVKYVLEGHDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNETKAWEVDTLRGHMNNVSSVMFHAKQDIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWILAVHPEMNLLAAGHDSGMIVFKLERERPAFALSGDSLFYAKDRFLRYYEYSTQRDSQVIPIRRPGTPSLNQSPRTLSYSPTENAVLICSDLDGGSYELYIIPKDSVGRSDVVQDAKRGTGGSAVFIARNRFAVLEKSTSQVLVKNLKNEVVKKSPLPIPTDAIFYAGTGNLLCRSEDKVVIFDLQQRLVLGELQTPFVRYVVWSSDMESVALLSKHTIIIASKKLVLQCTLHETIRVKSGAWDDNGVFIYTTLNHIKYCLPNGDSGIIRTLDVPIYITKVSGNTIFCLDRDGKNKAITINATEYIFKLSLLRKRYDHVMSMIKNSQLCGQAMIAYLQQKGFPEVALHFVEDERIRFNLALESGNISVAVASATQINEKDHWYRLGVEALRQGNSGIVEFAYQQTKNFERLSFLYLITGNLDKLSKLMKIAEVKNNVMGQFHNALYLGDVKERVKILENAGHLPLAYITASVHGLNDIAERLATELGDNVPSLPEGKTPSLLMPPTPIMCGGDWPLLRVMKGIFEGGLESADRGGTVDEEDVEGDWGEELDINVDGMENRDIEDILAAAEAGEEENDEEGGWGLEDLVLPPELDTPKASANARSSVFVTPPQGMPVSQSWSQKSSLAAEQAAAGSFDTAMRLLHRQLGIKNFTPLKSMFLDLFNGSHSYLRAFSSCPVVPLAIERGWSESSSPNVRSPPALVYDFSQLDEKLKSGYKATTTGKFTEALRLFLSILHTIPLVVVETRREVDEVKELIVIVKEYVLGLQMELKRREMKDDPVRQQELAAYFTHCNLQTPHLRLALLSAMGVCYKAKNLATASNFARRLLETSPVDSQAKMARQVVQAAERNMTDETKLNYDFRNPFVVCGSTYVPIYRGQKDVSCPYCTARFVPNQEGNICTVCDLAVIGADASGLLCSPSQVR", "length": 1216 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W0B8-1", "protein_name": "Coatomer subunit alpha", "gene_name": "alphaCOP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 1234 }, "evidence": [ { "id": "H9L3L2", "url": "https://omabrowser.org/oma/group/H9L3L2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "H9L3L2", "url": "https://www.uniprot.org/uniprotkb/H9L3L2" } ], "pmid": "" }, { "name": "growth cone", 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protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745" }, "gene_names": [ { "name": "MUSTN1", "type": "recommended", "evidence": [ { "id": "Q76MS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ] }, { "name": "MUSTN1", "type": "synonym", "evidence": [ { "id": "NP_998745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745" } ] }, { "name": "PD284", "type": "synonym", "evidence": [ { "id": "NP_998745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745" }, { "id": "Q76MS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ] } ], "protein_names": [ { "name": "Musculoskeletal embryonic nuclear protein 1", "type": "recommended", "evidence": [ { "id": "Q76MS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76MS9/entry#names_and_taxonomy" } ] }, { "name": "musculoskeletal embryonic nuclear protein 1", "type": "synonym", "evidence": [ { "id": "NP_998745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB040149.1, BU307873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140853 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000250.1.", "evidence": [ { "database": "RefSeq", "id": "NP_998745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745" } ] }, { "annotation": "Promotes the differentiation and proliferation of skeletal muscle satellite cells.", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9#function" }, { "database": "PubMed", "id": "34536390", "url": "https://glygen.org/publication/PubMed/34536390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MUSTN1", "url": "https://www.uniprot.org/uniprotkb/Q76MS9", "locus": { "chromosome": "12", "start_pos": 905035, "end_pos": 908631, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028080", "url": "https://www.ensembl.org/id/ENSGALG00010028080" } ] } } ], "crossref": [ { "id": "Q76MS9", "url": "https://alphafold.ebi.ac.uk/entry/Q76MS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001709", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001709", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "404773", "url": "https://www.ncbi.nlm.nih.gov/gene/404773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:404773", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEQMGSV", "url": "https://omabrowser.org/oma/group/CEQMGSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC27", "url": "https://www.orthodb.org/?gene=A0A8V1AC27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q76MS9", "url": "https://www.orthodb.org/?gene=Q76MS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15682", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15682", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q76MS9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q76MS9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_998745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q76MS9-1", "url": "https://www.uniprot.org/uniprotkb/Q76MS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQPDPVKKKRPPVKEEDLKGARGNLSKNQEIKSKTYQVMKQCEQMGSAAPSIFSRARTGSETVFEKSKDEPPKSVFG", "length": 78, "header": "sp|Q76MS9-1|MSTN1_CHICK Isoform 1 of Musculoskeletal embryonic nuclear protein 1 OS=Gallus gallus OX=9031 GN=MUSTN1 PE=2 SV=1 CANONICAL=Q76MS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC27-1", "url": "https://www.uniprot.org/uniprotkb/Q76MS9/entry#A0A8V1AC27-1", "sequence": { "sequence": "QNAVFLRLSVWESAQLCARFPWTTPTSSHCRQPWRCLAHSSPAQTLCEFGKPDPVKKKRPPVKEEDLKGARGNLSKNQEIKSKTYQVMKQCEQMGSAAPSIFSRARTGSETVFEKSKDEPPKSVFG", "length": 126, "header": "tr|A0A8V1AC27-1|MSTN1_CHICK Computationally mapped isoform of Musculoskeletal embryonic nuclear protein 1 OS=Gallus gallus OX=9031 GN=MUSTN1 PE=2 SV=1 CANONICAL=Q76MS9-1" }, "locus": { "chromosome": "12", "start_pos": 907264, "end_pos": 905277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068040.1", "url": "https://www.ensembl.org/id/ENSGALT00010068040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041783.1", "url": "https://www.ensembl.org/id/ENSGALP00010041783.1" } ] } }, { "isoform_ac": "Q76MS9-1", "url": "https://www.uniprot.org/uniprotkb/Q76MS9/entry#Q76MS9-1", "sequence": { "sequence": "MSQPDPVKKKRPPVKEEDLKGARGNLSKNQEIKSKTYQVMKQCEQMGSAAPSIFSRARTGSETVFEKSKDEPPKSVFG", "length": 78, "header": "sp|Q76MS9-1|MSTN1_CHICK Isoform 1 of Musculoskeletal embryonic nuclear protein 1 OS=Gallus gallus OX=9031 GN=MUSTN1 PE=2 SV=1 CANONICAL=Q76MS9-1" }, "locus": { "chromosome": "12", "start_pos": 908232, "end_pos": 905277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068041.1", "url": "https://www.ensembl.org/id/ENSGALT00010068041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041784.1", "url": "https://www.ensembl.org/id/ENSGALP00010041784.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "MUSTN1 mRNA Abundance and Protein Localization is Greatest in Muscle Tissues of Chinese Meat-Quality Chickens.", "journal": "Int. J. Mol. Sci.", "date": "2013", "authors": "Li Juan, Chen Yang, Wang Ya-Gang, Zhao Xiao-Ling, Gilbert Elizabeth Ruth, Liu Yi-Ping, Wang Yan, Hu Yao-Dong, Zhu Qing", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "reference": [ { "type": "PubMed", "id": "23528857", "url": "https://glygen.org/publication/PubMed/23528857" } ] }, { "title": "MUSTN1 is an indispensable factor in the proliferation, differentiation and apoptosis of skeletal muscle satellite cells in chicken.", "journal": "Experimental cell research", "date": "2021-10-15", "authors": "Hu Zhi, Xu Hengyong, Lu Yuxiang, He Qijian, Yan Chaoyang, Zhao Xiaoling, Tian Yaofu, Yang Chaowu, Zhang Zengrong, Qiu Mohan, Wang Yan", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "reference": [ { "type": "PubMed", "id": "34536390", "url": "https://glygen.org/publication/PubMed/34536390" } ] } ], "pathway": [ { "id": "gga:404773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404773", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LUT4-1", "protein_name": "Musculoskeletal embryonic nuclear protein 1", "gene_name": "Mustn1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEVGTPEAPIKKKRPPVKEEDLKGARGNLAKNQEIKSKTYQVMRDCEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG", "length": 82 }, "evidence": [ { "id": "Q76MS9", "url": "https://omabrowser.org/oma/group/Q76MS9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q32KU9-1", "protein_name": "Musculoskeletal embryonic nuclear protein 1", "gene_name": "MUSTN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQAGAQEAPIKKKRPPVKEEDLKGARGNLTKNQEIKSKTYQVMRECEQAGSTAPSVFSRARTGAETVFEKPKAGPAKSVFG", "length": 82 }, "evidence": [ { "id": "Q76MS9", "url": "https://omabrowser.org/oma/group/Q76MS9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IVN3-1", "protein_name": "Musculoskeletal embryonic nuclear protein 1", "gene_name": "MUSTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQAGAQEAPIKKKRPPVKDEDLKGARGNLTKNQEIKSKTYQVMRECEQAGSAAPSVFSRTRTGTETVFEKPKAGPTKSVFG", "length": 82 }, "evidence": [ { "id": "Q76MS9", "url": "https://omabrowser.org/oma/group/Q76MS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JI1-1", "protein_name": "Musculoskeletal embryonic nuclear protein 1", "gene_name": "Mustn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEAGTPEGPIKKKRPPVKEEDLKGARGTLAKNQDIKSKTYQVMRDYEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG", "length": 82 }, "evidence": [ { "id": "Q76MS9", "url": "https://omabrowser.org/oma/group/Q76MS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "skeletal muscle satellite cell differentiation", "id": "GO:0014816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014816", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" }, { "name": "tissue regeneration", "id": "GO:0042246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042246", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" }, { "name": "chondrocyte proliferation", "id": "GO:0035988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035988", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell proliferation", "id": "GO:0014841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014841", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q76MS9", "url": "https://www.uniprot.org/uniprotkb/Q76MS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q76MS9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 78, "overlap": "1.0", "method": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1P3C2-1", "uniprot_ac": "F1P3C2", "uniprot_id": "F1P3C2_CHICK", "mass": { "chemical_mass": 90385.0, "monoisotopic_mass": 90385.0 }, "refseq": { "ac": "XP_015150817", "name": "RING finger protein unkempt homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150817" }, "gene_names": [ { "name": "UNK", "type": "recommended", "evidence": [ { "id": "F1P3C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ] }, { "name": "UNK", "type": "synonym", "evidence": [ { "id": "XP_015150817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150817" } ] } ], "protein_names": [ { "name": "RING finger protein unkempt homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150817" } ] }, { "name": "Unk zinc finger", "type": "synonym", "evidence": [ { "id": "F1P3C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150817" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNK", "url": "https://www.uniprot.org/uniprotkb/F1P3C2", "locus": { "chromosome": "18", "start_pos": 5292217, "end_pos": 5329309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029782", "url": "https://www.ensembl.org/id/ENSGALG00010029782" } ] } } ], "crossref": [ { "id": "F1P3C2", "url": "https://alphafold.ebi.ac.uk/entry/F1P3C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002278", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417371", "url": "https://www.ncbi.nlm.nih.gov/gene/417371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417371", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCACEAW", "url": "https://omabrowser.org/oma/group/KCACEAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFE2", "url": "https://www.orthodb.org/?gene=A0A8V1AFE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ64", "url": "https://www.orthodb.org/?gene=A0A8V1AQ64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3C2", "url": "https://www.orthodb.org/?gene=F1P3C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14493", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14493", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14493:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14493:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3C2-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKGPVASGPAAAGPANAASALQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDIYCTKYDETTGICPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGVHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTSEGGIEGQSAVAASHAMIEKILSEEPRWQDTTYVLGNYKTEQCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPSVKHGDEWGDPSKCENGDSCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLNEDLQQSSAVSSPTQAGPVMYMPSAAGDSVPVSPSSPHAPDLSNVWNKSGTLPTSPTSTTILCRNSSLGSPSNICGSPPGAIGKPHSLESIGFPPDSVTAAGSYKKAPGFEREDQVGAEYLKSFKCQQAKMKSHSLEHRSQEQPLLQPKQDILGILPVGSPLTSSISSSITSSLAATPPSPAGTSSIPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDSSTVPHTSGIMIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLHQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPSTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEANDRANTANMECELAREQREALELQVKKLQEELERIHTGQDPQFLRSFSDLETLSLSSLYTLQKQLRANLEKVDKAVFQMQSVKCLKCQEENRVVLPCQHAVLCETCAKEGECPICHPNRPHALQS", "length": 825, "header": "tr|F1P3C2-1|F1P3C2_CHICK Isoform 1 of Unk zinc finger OS=Gallus gallus OX=9031 GN=UNK PE=1 SV=3 CANONICAL=F1P3C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFE2-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C2/entry#A0A8V1AFE2-1", "sequence": { "sequence": "MSKGPVASGPAAAGPANAASALQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDIYCTKYDETTGICPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGVHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTSEGGIEGQSAVAASHAMIEKILSEEPRWQDTTYVLGNYKTEQCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPSVKHGDEWGDPSKCENGDSCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLNEDLQQSSAVSSPTQAGPVMYMPSAAGDSVPVSPSSPHAPDLSNVWNKSGTLPTSPTSTTILCRNSSLGSPSNICGSPPGAIGKPHSLESIGFPPDSVTAAGSYKKAPGFEREDQVGAEYLKSFKCQQAKMKSHSLEHRSQEQPLLQPKQDILGILPVGSPLTSSISSSITSSLAATPPSPAGTSSIPGMNANALPFYPTSDTVESVIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLHQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPSTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEANDRANTANMECELAREQREALELQVKKLQEELERIHTGQDPQFLRSFSDLETLSLSSLYTLQKQLRANLEKVDKAVFQMQSVKCLKCQEENRVVLPCQHAVLCETCAKEGECPICHPNRPHALQS", "length": 791, "header": "tr|A0A8V1AFE2-1|F1P3C2_CHICK Computationally mapped isoform of Unk zinc finger OS=Gallus gallus OX=9031 GN=UNK PE=1 SV=1 CANONICAL=F1P3C2-1" }, "locus": { "chromosome": "18", "start_pos": 5329120, "end_pos": 5292885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072050.1", "url": "https://www.ensembl.org/id/ENSGALT00010072050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044740.1", "url": "https://www.ensembl.org/id/ENSGALP00010044740.1" } ] } }, { "isoform_ac": "A0A8V1AQ64-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C2/entry#A0A8V1AQ64-1", "sequence": { "sequence": "MSKGPVASGPAAAGPANAASALQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDIYCTKYDETTGICPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGVHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTSEGGIEGQSAVAASHAMIEKILSEEPRWQDTTYVLGNYKTEQCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPSVKHGDEWGDPSKCENGDSCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLNEDLQQSSAVSSPTQAGPVMYMPSAAGDSVPVSPSSPHAPDLSNILCRNSSLGSPSNICGSPPGAIGKPHSLESIGFPPDSVTAAGSYKKAPGFEREDQVGAEYLKSFKCQQAKMKSHSLEHRSQEQPLLQPKQDILGILPVGSPLTSSISSSITSSLAATPPSPAGTSSIPGMNANALPFYPTSDTVESVIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLHQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPSTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEANDRANTANMECELAREQREALELQVKKLQEELERIHTGQDPQFLRSFSDLETLSLSSLYTLQKQLRANLEKVDKAVFQMQSVKCLKCQEENRVVLPCQHAVLCETCAKEGECPICHPNRPHALQS", "length": 775, "header": "tr|A0A8V1AQ64-1|F1P3C2_CHICK Computationally mapped isoform of Unk zinc finger OS=Gallus gallus OX=9031 GN=UNK PE=1 SV=1 CANONICAL=F1P3C2-1" }, "locus": { "chromosome": "18", "start_pos": 5329120, "end_pos": 5292885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072051.1", "url": "https://www.ensembl.org/id/ENSGALT00010072051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044741.1", "url": "https://www.ensembl.org/id/ENSGALP00010044741.1" } ] } }, { "isoform_ac": "F1P3C2-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C2/entry#F1P3C2-1", "sequence": { "sequence": "MSKGPVASGPAAAGPANAASALQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDIYCTKYDETTGICPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGVHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTSEGGIEGQSAVAASHAMIEKILSEEPRWQDTTYVLGNYKTEQCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPSVKHGDEWGDPSKCENGDSCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLNEDLQQSSAVSSPTQAGPVMYMPSAAGDSVPVSPSSPHAPDLSNVWNKSGTLPTSPTSTTILCRNSSLGSPSNICGSPPGAIGKPHSLESIGFPPDSVTAAGSYKKAPGFEREDQVGAEYLKSFKCQQAKMKSHSLEHRSQEQPLLQPKQDILGILPVGSPLTSSISSSITSSLAATPPSPAGTSSIPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDSSTVPHTSGIMIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLHQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPSTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEANDRANTANMECELAREQREALELQVKKLQEELERIHTGQDPQFLRSFSDLETLSLSSLYTLQKQLRANLEKVDKAVFQMQSVKCLKCQEENRVVLPCQHAVLCETCAKEGECPICHPNRPHALQS", "length": 825, "header": "tr|F1P3C2-1|F1P3C2_CHICK Isoform 1 of Unk zinc finger OS=Gallus gallus OX=9031 GN=UNK PE=1 SV=3 CANONICAL=F1P3C2-1" }, "locus": { "chromosome": "18", "start_pos": 5329120, "end_pos": 5292885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072049.1", "url": "https://www.ensembl.org/id/ENSGALT00010072049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044739.1", "url": "https://www.ensembl.org/id/ENSGALP00010044739.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZV40-1", "protein_name": "Unk zinc finger", "gene_name": "Unk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQGIADPQHPGHRPQRSLGIVVLHFSSDAVPTVKFHPKGGPQLPATFAAVRGVFTFSWRGAGAVGLRRGPRRLNNKRGAAKRQEDRTMSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDTCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHIEPPPLSDDVPPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRSSGLASPPHLCSSPPGPSRKISNLEGLVFPGEASLAPGSYKKAPGCEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSAPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPSNITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTRTVLPCQHAVLCELCAEGSECPVCQPGRAHALQS", "length": 898 }, "evidence": [ { "id": "F1P3C2", "url": "https://omabrowser.org/oma/group/F1P3C2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RVY8-1", "protein_name": "Unk zinc finger", "gene_name": "UNK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLGDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNLKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPVGSPLTSSISSSITSSLAATPPSPAGTSSVPGMNANALPFYPASDTVESVIESALDDLDLNEFGVAALEKTFDSSSVPHPGSITVGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDAMEAQVKKLQEELERLHSGPDPQALPAFSDLETLSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQNRAVLPCQHAVLCELCAEGSECPVCQPGRAHTLQS", "length": 810 }, "evidence": [ { "id": "F1P3C2", "url": "https://omabrowser.org/oma/group/F1P3C2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BL48-1", "protein_name": "RING finger protein unkempt homolog", "gene_name": "Unk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPLSDDVQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSGLGSPSHLCSSPPGPSRKASNLEGLVFPGESSLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPSPAGTNSTPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSAVPHPSSVTIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTRAVLPCQHAVLCELCAEGSECPVCQPSRAHALQS", "length": 810 }, "evidence": [ { "id": "F1P3C2", "url": "https://omabrowser.org/oma/group/F1P3C2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0B0-1", "protein_name": "RING finger protein unkempt homolog", "gene_name": "UNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTTVEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSSLAATPPSPVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQSENTFLGTSASHGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGPGAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKRAVLPCQHAALCELCAEGSECPICQPGRAHTLQS", "length": 810 }, "evidence": [ { "id": "F1P3C2", "url": "https://omabrowser.org/oma/group/F1P3C2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" }, { "name": "mRNA CDS binding", "id": "GO:1990715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990715", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "F1P3C2", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P3C2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 825, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P3C2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P3C2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P3C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C2" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 111, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "P32429-1", "uniprot_ac": "P32429", "uniprot_id": "RL7A_CHICK", "mass": { "chemical_mass": 30000.0, "monoisotopic_mass": 30000.0 }, "refseq": { "ac": "NP_001004379", "name": "large ribosomal subunit protein eL8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379" }, "gene_names": [ { "name": "RPL7A", "type": "recommended", "evidence": [ { "id": "P32429", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32429" } ] }, { "name": "RPL7A", "type": "synonym", "evidence": [ { "id": "NP_001004379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379" } ] }, { "name": "SURF-3", "type": "synonym", "evidence": [ { "id": "P32429", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32429" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL8", "type": "recommended", "evidence": [ { "id": "P32429", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32429/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L7a", "type": "synonym", "evidence": [ { "id": "NP_001004379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379" }, { "id": "P32429", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32429/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL8", "type": "synonym", "evidence": [ { "id": "NP_001004379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CF257685.1, BU111922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Sep 17, 2004 this sequence version replaced XP_415441.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429#function" }, { "database": "UniProtKB", "id": "P62424", "url": "https://www.uniprot.org/uniprotkb/P62424#function" } ] }, { "annotation": "Component of the ribosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT5#function" }, { "database": "UniProtKB", "id": "RU367042", "url": "https://www.uniprot.org/uniprotkb/RU367042#function" }, { "database": "UniProtKB", "id": "A0A8V1AFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL7A", "url": "https://www.uniprot.org/uniprotkb/P32429", "locus": { "chromosome": "17", "start_pos": 7476787, "end_pos": 7472400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028854", "url": "https://www.ensembl.org/id/ENSGALG00010028854" } ] } } ], "crossref": [ { "id": "P32429", "url": "https://alphafold.ebi.ac.uk/entry/P32429", "database": "AlphaFoldDB", "categories": [] }, { "id": "417158", "url": "https://www.ncbi.nlm.nih.gov/gene/417158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417158", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417158", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMVKWPA", "url": "https://omabrowser.org/oma/group/RMVKWPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFP6", "url": "https://www.orthodb.org/?gene=A0A8V1AFP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALT5", "url": "https://www.orthodb.org/?gene=A0A8V1ALT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P32429", "url": "https://www.orthodb.org/?gene=P32429", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P32429", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P32429", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001004379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P32429-1", "url": "https://www.uniprot.org/uniprotkb/P32429-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRSILYKRLKVPPAINQFSQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEQKAAGKGDTPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKSKARLGRLVHRKTCTCVAFTQVNPEDKGALAKLVEAVKTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266, "header": "sp|P32429-1|RL7A_CHICK Isoform 1 of Large ribosomal subunit protein eL8 OS=Gallus gallus OX=9031 GN=RPL7A PE=1 SV=2 CANONICAL=P32429-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFP6-1", "url": "https://www.uniprot.org/uniprotkb/P32429/entry#A0A8V1AFP6-1", "sequence": { "sequence": "KHIFEVACVLFKCIKHLRFKKKKTKCLSYLQPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRSILYKRLKVPPAINQFSQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEQKAAGKGDTPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKSKARLGRLVHRKTCTCVAFTQVNPEDKGALAKLVEAVKTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 296, "header": "tr|A0A8V1AFP6-1|RL7A_CHICK Computationally mapped isoform of Large ribosomal subunit protein eL8 OS=Gallus gallus OX=9031 GN=RPL7A PE=1 SV=1 CANONICAL=P32429-1" }, "locus": { "chromosome": "17", "start_pos": 7475941, "end_pos": 7472784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069798.1", "url": "https://www.ensembl.org/id/ENSGALT00010069798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042924.1", "url": "https://www.ensembl.org/id/ENSGALP00010042924.1" } ] } }, { "isoform_ac": "A0A8V1ALT5-1", "url": "https://www.uniprot.org/uniprotkb/P32429/entry#A0A8V1ALT5-1", "sequence": { "sequence": "KHIFEVACVLFKCIKHLRFKKKKTKCLSYLQPKGKKAKGKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRSILYKRLKVPPAINQFSQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEQKAAGKGDTPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKSKARLGRLVHRKTCTCVAFTQVNPEDKGALAKLVEAVKTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 281, "header": "tr|A0A8V1ALT5-1|RL7A_CHICK Computationally mapped isoform of Large ribosomal subunit protein eL8 OS=Gallus gallus OX=9031 GN=RPL7A PE=1 SV=1 CANONICAL=P32429-1" }, "locus": { "chromosome": "17", "start_pos": 7475941, "end_pos": 7472784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069797.1", "url": "https://www.ensembl.org/id/ENSGALT00010069797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042923.1", "url": "https://www.ensembl.org/id/ENSGALP00010042923.1" } ] } }, { "isoform_ac": "P32429-1", "url": "https://www.uniprot.org/uniprotkb/P32429/entry#P32429-1", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRSILYKRLKVPPAINQFSQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEQKAAGKGDTPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKSKARLGRLVHRKTCTCVAFTQVNPEDKGALAKLVEAVKTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266, "header": "sp|P32429-1|RL7A_CHICK Isoform 1 of Large ribosomal subunit protein eL8 OS=Gallus gallus OX=9031 GN=RPL7A PE=1 SV=2 CANONICAL=P32429-1" }, "locus": { "chromosome": "17", "start_pos": 7475941, "end_pos": 7472419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069799.1", "url": "https://www.ensembl.org/id/ENSGALT00010069799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042925.1", "url": "https://www.ensembl.org/id/ENSGALP00010042925.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1992", "authors": "Colombo P, Yon J, Garson K, Fried M", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "reference": [ { "type": "PubMed", "id": "1631131", "url": "https://glygen.org/publication/PubMed/1631131" } ] }, { "title": "The complete nucleotide sequence of chicken ribosomal protein L7a gene and the multiple factor binding sites in its 5'-flanking region.", "journal": "Biochimie", "date": "1993", "authors": "Maeda N, Kenmochi N, Tanaka T", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "reference": [ { "type": "PubMed", "id": "8274530", "url": "https://glygen.org/publication/PubMed/8274530" } ] } ], "pathway": [ { "id": "gga:417158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417158", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P12970-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P29453-1", "protein_name": "Large ribosomal subunit protein eL8B", "gene_name": "RPL8B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKTSDSA", "length": 256 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46223-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "RpL7A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVVKKPRPKKKPVTKKVAPAPLAVKKPVVKKVVNQLFEKRPKNFGIGQNVQPKRDLSRFVRWPKYIRVQRQKAVLQKRLKVPPPIHQFSQTLDKTTAVKLFKLLEKYRPESPLAKKLRLKKIAEAKAKGKDVEPKKKPSYVSAGTNTVTKLIEQKKAQLVVIAHDVDPLELVLFLPALCRKMGVPYCIVKGKARLGRLVRRKTCTTLALTTVDNNDKANFGKVLEAVKTNFNERHEEIRRHWGGGILGSKSLARISKLERAKARELAQKQG", "length": 271 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P49692-1", "protein_name": "Large ribosomal subunit protein eL8z", "gene_name": "RPL7AA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPKKGVKVAAKKKTAEKVSNPLFERRPKQFGIGGALPPKKDLSRYIKWPKSIRLQRQKRILKQRLKVPPALNQFTKTLDKNLATSLFKVLLKYRPEDKAAKKERLVKKAQAEAEGKPSESKKPIVVKYGLNHVTYLIEQNKAQLVVIAHDVDPIELVVWLPALCRKMEVPYCIVKGKSRLGAVVHQKTASCLCLTTVKNEDKLEFSKILEAIKANFNDKYEEYRKKWGGGIMGSKSQAKTKAKERVIAKEAAQRMN", "length": 257 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P62424-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "RPL7A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TBQ5-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "RPL7A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKSALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54ZD1-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "rpl7a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQKQTKPAAATKAAPAKTAVATTKSKKVVKKGEKKIKTRTLFNALYTKNVKNFGTGFGVQPKRDLTHFTHWPRYIKLQRQRRVLLKRLKVPPTINQFTRVFDKNTAVHLFKLLDKYRPEEASVKKARLLKIAEARAATPKGQAAPKAEKPVQHLRFGIDSVTKLIEKKKAKLVVIAHDVDPVELVLYLPTLCRRMDVPYCIVKSKSRLGELVHMRNASCVALTGVNSADSNELALLVESAKQMFNNNSEHRKTWGGNTLSGPARAILAKRQKAEAKESLAKSKI", "length": 285 }, "evidence": [ { "id": "P32429", "url": "https://omabrowser.org/oma/group/P32429/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": 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"UniProtKB", "id": "P32429", "url": "https://www.uniprot.org/uniprotkb/P32429" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P32429-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 266, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P32429-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P32429" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q98TF6-1", "uniprot_ac": "Q98TF6", "uniprot_id": "RL36_CHICK", "mass": { "chemical_mass": 12296.0, "monoisotopic_mass": 12296.0 }, "refseq": { "ac": "NP_989471", "name": "large ribosomal subunit protein eL36", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471" }, "gene_names": [ { "name": "RPL36", "type": "recommended", "evidence": [ { "id": "Q98TF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ] }, { "name": "RPL36", "type": "synonym", "evidence": [ { "id": "NP_989471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL36", "type": "recommended", "evidence": [ { "id": "Q98TF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF6/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L36", "type": "synonym", "evidence": [ { "id": "NP_989471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471" }, { "id": "Q98TF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF6/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL36", "type": "synonym", "evidence": [ { "id": "NP_989471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CF250267.1, CN226533.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000374.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH32#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" }, { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6#function" }, { "database": "UniProtKB", "id": "Q9Y3U8", "url": "https://www.uniprot.org/uniprotkb/Q9Y3U8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL36", "url": "https://www.uniprot.org/uniprotkb/Q98TF6", "locus": { "chromosome": "28", "start_pos": 1266786, "end_pos": 1088280, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027609", "url": "https://www.ensembl.org/id/ENSGALG00010027609" } ] } } ], "crossref": [ { "id": "Q98TF6", "url": "https://alphafold.ebi.ac.uk/entry/Q98TF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000474", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "373936", "url": "https://www.ncbi.nlm.nih.gov/gene/373936", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:373936", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373936", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKGHKTE", "url": "https://omabrowser.org/oma/group/NKGHKTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH32", "url": "https://www.orthodb.org/?gene=A0A8V1AH32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q98TF6", "url": "https://www.orthodb.org/?gene=Q98TF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q98TF6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q98TF6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AH32", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98TF6-1", "url": "https://www.uniprot.org/uniprotkb/Q98TF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIRYPMAVGLNKGYKVTKNVSKPRHCRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 105, "header": "sp|Q98TF6-1|RL36_CHICK Isoform 1 of Large ribosomal subunit protein eL36 OS=Gallus gallus OX=9031 GN=RPL36 PE=1 SV=1 CANONICAL=Q98TF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH32-1", "url": "https://www.uniprot.org/uniprotkb/Q98TF6/entry#A0A8V1AH32-1", "sequence": { "sequence": "MTSSALPLHCILPFLIPSLQIGTHTVIHQHSDCVFSKAACMPLDLCITGVGRDLEGSLSPISCRAVPYNRSASSQVFLSPYPSSSEPCRARGRAVVVLALCKGWLWHSGCFSAYVDCERCFSFPFQQRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 201, "header": "tr|A0A8V1AH32-1|RL36_CHICK Computationally mapped isoform of Large ribosomal subunit protein eL36 OS=Gallus gallus OX=9031 GN=RPL36 PE=1 SV=1 CANONICAL=Q98TF6-1" }, "locus": { "chromosome": "28", "start_pos": 1091016, "end_pos": 1089842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066887.1", "url": "https://www.ensembl.org/id/ENSGALT00010066887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040918.1", "url": "https://www.ensembl.org/id/ENSGALP00010040918.1" } ] } }, { "isoform_ac": "Q98TF6-1", "url": "https://www.uniprot.org/uniprotkb/Q98TF6/entry#Q98TF6-1", "sequence": { "sequence": "MAIRYPMAVGLNKGYKVTKNVSKPRHCRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 105, "header": "sp|Q98TF6-1|RL36_CHICK Isoform 1 of Large ribosomal subunit protein eL36 OS=Gallus gallus OX=9031 GN=RPL36 PE=1 SV=1 CANONICAL=Q98TF6-1" }, "locus": { "chromosome": "28", "start_pos": 1091016, "end_pos": 1088499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066888.1", "url": "https://www.ensembl.org/id/ENSGALT00010066888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040919.1", "url": "https://www.ensembl.org/id/ENSGALP00010040919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.", "journal": "Genomics", "date": "2001", "authors": "Uechi T, Tanaka T, Kenmochi N", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "reference": [ { "type": "PubMed", "id": "11401437", "url": "https://glygen.org/publication/PubMed/11401437" } ] } ], "pathway": [ { "id": "gga:373936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373936", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "C0HME6-1", "protein_name": "RPL36 alternative reading frame protein", "gene_name": "RPL36", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "length": 148 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZZ95-1", "protein_name": "60S ribosomal protein L36", "gene_name": "Rpl36l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRYPMAVGLNKGHKVTKNVSKPRHSRRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 106 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14455-1", "protein_name": "Large ribosomal subunit protein eL36B", "gene_name": "RPL36B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVKTGIAIGLNKGKKVTQMTPAPKISYKKGAASNRTKFVRSLVREIAGLSPYERRLIDLIRNSGEKRARKVAKKRLGSFTRAKAKVEEMNNIIAASRRH", "length": 100 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P47964-1", "protein_name": "Large ribosomal subunit protein eL36", "gene_name": "Rpl36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 105 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49630-1", "protein_name": "Large ribosomal subunit protein eL36", "gene_name": "RpL36", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVRYELAIGLNKGHKTSKIRNVKYTGDKKVKGLRGSRLKNIQTRHTKFMRDLVREVVGHAPYEKRTMELLKVSKDKRALKFLKRRLGTHIRAKRKREELSNILTQLRKAQTHAK", "length": 115 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3T171-1", "protein_name": "Large ribosomal subunit protein eL36", "gene_name": "RPL36", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALRYPMAVGLNKGHKVTKNVGKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD", "length": 105 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55AQ9-1", "protein_name": "Large ribosomal subunit protein eL36", "gene_name": "rpl36", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSAATKPVKRSGIIKGFNKGHAVAKRTVTSTFKKQVVTKRVAAIRDVIREISGFSPYERRVSELLKSGLDKRALKVAKKRLGSIQAGKKKRDDIANINRKASAK", "length": 105 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6Q415-1", "protein_name": "Large ribosomal subunit protein eL36", "gene_name": "rpl36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVVRYPMAVGLNKGHKVTKNVSKPKHSRRRGRLTKHAKFARDLIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNTLAAMRKAAAKKE", "length": 105 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9M352-1", "protein_name": "Large ribosomal subunit protein eL36y", "gene_name": "RPL36B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTTPQVKTGLFVGLNKGHVVTRRELAPRPRSRKGKTSKRTIFIRNLIKEVAGQAPYEKRITELLKVGKDKRALKVAKRKLGTHKRAKRKREEMSSVLRKMRSGGGGATEKKK", "length": 112 }, "evidence": [ { "id": "Q98TF6", "url": "https://omabrowser.org/oma/group/Q98TF6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q98TF6", "url": "https://www.uniprot.org/uniprotkb/Q98TF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q98TF6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 105, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q98TF6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q98TF6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GG02-1", "uniprot_ac": "R4GG02", "uniprot_id": "R4GG02_CHICK", "mass": { "chemical_mass": 35694.0, "monoisotopic_mass": 35694.0 }, "refseq": {}, "gene_names": [ { "name": "FN3KRP", "type": "recommended", "evidence": [ { "id": "R4GG02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ] } ], "protein_names": [ { "name": "protein-ribulosamine 3-kinase", "type": "recommended", "evidence": [ { "id": "R4GG02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG02/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.172", "type": "synonym", "evidence": [ { "id": "R4GG02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FN3KRP", "url": "https://www.uniprot.org/uniprotkb/R4GG02", "locus": { "chromosome": "18", "start_pos": 3979124, "end_pos": 3985489, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029430", "url": "https://www.ensembl.org/id/ENSGALG00010029430" } ] } } ], "crossref": [ { "id": "R4GG02", "url": "https://alphafold.ebi.ac.uk/entry/R4GG02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028979", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028979", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK86", "url": "https://www.orthodb.org/?gene=A0A8V1AK86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GG02", "url": "https://www.orthodb.org/?gene=R4GG02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12149:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12149:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163841", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "48432", "url": "https://www.rhea-db.org/rhea/48432", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61392", "url": "https://www.rhea-db.org/rhea/61392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AK86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GG02-1", "url": "https://www.uniprot.org/uniprotkb/R4GG02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSALAAAGGMEEALRRELGTSVLRATGHLGGGCISQGQSYETDGGRVYVKSNSKPEARRMFEGEMASLEAILKTGTIKVPKPIKVIDLPGVTTLFVMEHLEMRGLNRHSSKLGTQLADLHLHNQQLGEKLKKEESTVGKGQGQMEVQFVDQFGFHTVTCCGYLPQVNDWQADWVTFFARQRIQPQMDMIEKNSGDREARELWARLQLKIPSLFCDVEIVPALLHGDLWGGNVAEDDSGPIIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHSKIPKAPGFEKRLKLYQLFHYMNHWNHFGSGYRGSSLNIMRNLVK", "length": 320, "header": "tr|R4GG02-1|R4GG02_CHICK Isoform 1 of protein-ribulosamine 3-kinase OS=Gallus gallus OX=9031 GN=FN3KRP PE=1 SV=3 CANONICAL=R4GG02-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK86-1", "url": "https://www.uniprot.org/uniprotkb/R4GG02/entry#A0A8V1AK86-1", "sequence": { "sequence": "MLSSALAAAGGMEEALRRELGTSVLRATGHLGGGCISQGQSYETDGGRVYVKSNSKPEARRMFEGEMASLEAILKTGTIKVPKPIKVIDLPGVTTLFVMEHLEMRGLNRHSSKLGTQLADLHLHNQQLGEKLKKEESTVNDWQADWVTFFARQRIQPQMDMIEKNSGDREARELWARLQLKIPSLFCDVEIVPALLHGDLWGGNVAEDDSGPIIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHSKIPKAPGFEKRLKLYQLFHYMNHWNHFGSGYRGSSLNIMRNLVK", "length": 291, "header": "tr|A0A8V1AK86-1|R4GG02_CHICK Computationally mapped isoform of protein-ribulosamine 3-kinase OS=Gallus gallus OX=9031 GN=FN3KRP PE=1 SV=1 CANONICAL=R4GG02-1" }, "locus": { "chromosome": "18", "start_pos": 3985485, "end_pos": 3980661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071202.1", "url": "https://www.ensembl.org/id/ENSGALT00010071202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043893.1", "url": "https://www.ensembl.org/id/ENSGALP00010043893.1" } ] } }, { "isoform_ac": "R4GG02-1", "url": "https://www.uniprot.org/uniprotkb/R4GG02/entry#R4GG02-1", "sequence": { "sequence": "MLSSALAAAGGMEEALRRELGTSVLRATGHLGGGCISQGQSYETDGGRVYVKSNSKPEARRMFEGEMASLEAILKTGTIKVPKPIKVIDLPGVTTLFVMEHLEMRGLNRHSSKLGTQLADLHLHNQQLGEKLKKEESTVGKGQGQMEVQFVDQFGFHTVTCCGYLPQVNDWQADWVTFFARQRIQPQMDMIEKNSGDREARELWARLQLKIPSLFCDVEIVPALLHGDLWGGNVAEDDSGPIIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHSKIPKAPGFEKRLKLYQLFHYMNHWNHFGSGYRGSSLNIMRNLVK", "length": 320, "header": "tr|R4GG02-1|R4GG02_CHICK Isoform 1 of protein-ribulosamine 3-kinase OS=Gallus gallus OX=9031 GN=FN3KRP PE=1 SV=3 CANONICAL=R4GG02-1" }, "locus": { "chromosome": "18", "start_pos": 3985485, "end_pos": 3980661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071201.1", "url": "https://www.ensembl.org/id/ENSGALT00010071201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043892.1", "url": "https://www.ensembl.org/id/ENSGALP00010043892.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-163841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163841", "resource": "Reactome", "description": "Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ], "pmid": "" }, { "name": "protein-ribulosamine 3-kinase activity", "id": "GO:0102193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102193", "evidence": [ { "database": "UniProtKB", "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GG02", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48432", "name": "", "equation": "N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BRW8-1", "R4GG02-1" ], "evidence": [ { "id": "48432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48432" } ] }, { "id": "61392", "name": "", "equation": "N(6)-(D-psicosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GG02-1", "E1BRW8-1" ], "evidence": [ { "id": "61392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61392" } ] }, { "id": "R-GGA-6788855", "name": "FN3KRP phosphorylates PsiAm, RibAm", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GG02-1" ], "evidence": [ { "id": "R-GGA-6788855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6788855" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BRW8", "gene_name": "FN3K", "activity": [ { "ec_number": "2.7.1.172", "activity": "N(6)-(D-erythrulosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BRW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRW8" } ] }, { "ec_number": "2.7.1.172", "activity": "", "evidence": [ { "id": "E1BRW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRW8" } ] } ] }, { "uniprot_ac": "R4GG02", "gene_name": "FN3KRP", "activity": [ { "ec_number": "2.7.1.172", "activity": "N(6)-(D-erythrulosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GG02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ] }, { "ec_number": "2.7.1.172", "activity": "", "evidence": [ { "id": "R4GG02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG02" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GG02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GG02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GG02" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.172", "ec_name": "N(6)-(D-erythrulosyl)-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.1.172", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.172" }, { "id": "2.7.1.172", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.172" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P573-1", "uniprot_ac": "F1P573", "uniprot_id": "F1P573_CHICK", "mass": { "chemical_mass": 19766.0, "monoisotopic_mass": 19766.0 }, "refseq": { "ac": "NP_001001328", "name": "vitamin K epoxide reductase complex subunit 1-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001328" }, "gene_names": [ { "name": "VKORC1L1", "type": "recommended", "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ] }, { "name": "VKORC1L1", "type": "synonym", "evidence": [ { "id": "NP_001001328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001328" } ] } ], "protein_names": [ { "name": "vitamin-K-epoxide reductase (warfarin-sensitive)", "type": "recommended", "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573/entry#names_and_taxonomy" } ] }, { "name": "1.17.4.4", "type": "synonym", "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573/entry#names_and_taxonomy" } ] }, { "name": "vitamin K epoxide reductase complex subunit 1-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001001328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001328" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01028484.1, SRR13267658.653.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with Hugh Robertson. The reference sequence was derived from JAENSK010000323.1. On Aug 30, 2004 this sequence version replaced XP_415791.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001328" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VKORC1L1", "url": "https://www.uniprot.org/uniprotkb/F1P573", "locus": { "chromosome": "19", "start_pos": 5407153, "end_pos": 5393893, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029659", "url": "https://www.ensembl.org/id/ENSGALG00010029659" } ] } } ], "crossref": [ { "id": "F1P573", "url": "https://alphafold.ebi.ac.uk/entry/F1P573", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002501", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12917", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12917", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "408253", "url": "https://www.ncbi.nlm.nih.gov/gene/408253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:408253", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFCVVCV", "url": "https://omabrowser.org/oma/group/EFCVVCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALG8", "url": "https://www.orthodb.org/?gene=A0A8V1ALG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P573", "url": "https://www.orthodb.org/?gene=F1P573", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14519:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14519:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6806664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6806664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001001328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001328", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P573-1", "url": "https://www.uniprot.org/uniprotkb/F1P573-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPVLLRVSVPRWERVARSAVCAAGILLSLYACHLEREKGRDLHYQALCDLSERVRCSAAITSRWGRGFGLLGSIFGKDSAINQSNSVFGLVFYILQMLLGMTASAVAALILMTSSIVSVVGSLYLAYILYFVLKEFCIVCVITYLLNFILFIINYKRLVYLNEAWKRQLQPKQE", "length": 176, "header": "tr|F1P573-1|F1P573_CHICK Isoform 1 of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Gallus gallus OX=9031 GN=VKORC1L1 PE=1 SV=2 CANONICAL=F1P573-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALG8-1", "url": "https://www.uniprot.org/uniprotkb/F1P573/entry#A0A8V1ALG8-1", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARSAVCAAGILLSLYACHLEREKGRDLHYQALCDLSERVRCSAAITSRWGRGFGLLGSIFGKDSAINQSNSVFGLVFYILQMLLASAVAALILMTSSIVSVVGSLYLAYILYFVLKEFCIVCVITYLLNFILFIINYKRLVYLNEAWKRQLQPKQE", "length": 173, "header": "tr|A0A8V1ALG8-1|F1P573_CHICK Computationally mapped isoform of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Gallus gallus OX=9031 GN=VKORC1L1 PE=1 SV=1 CANONICAL=F1P573-1" }, "locus": { "chromosome": "19", "start_pos": 5403307, "end_pos": 5393904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071710.1", "url": "https://www.ensembl.org/id/ENSGALT00010071710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044400.1", "url": "https://www.ensembl.org/id/ENSGALP00010044400.1" } ] } }, { "isoform_ac": "F1P573-1", "url": "https://www.uniprot.org/uniprotkb/F1P573/entry#F1P573-1", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARSAVCAAGILLSLYACHLEREKGRDLHYQALCDLSERVRCSAAITSRWGRGFGLLGSIFGKDSAINQSNSVFGLVFYILQMLLGMTASAVAALILMTSSIVSVVGSLYLAYILYFVLKEFCIVCVITYLLNFILFIINYKRLVYLNEAWKRQLQPKQE", "length": 176, "header": "tr|F1P573-1|F1P573_CHICK Isoform 1 of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Gallus gallus OX=9031 GN=VKORC1L1 PE=1 SV=2 CANONICAL=F1P573-1" }, "locus": { "chromosome": "19", "start_pos": 5403307, "end_pos": 5393904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071711.1", "url": "https://www.ensembl.org/id/ENSGALT00010071711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044401.1", "url": "https://www.ensembl.org/id/ENSGALP00010044401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:408253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408253", "resource": "KEGG Pathway" }, { "id": "R-GGA-6806664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6806664", "resource": "Reactome", "description": "Metabolism of vitamin K" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6TEK5-1", "protein_name": "Vitamin K epoxide reductase complex subunit 1-like protein 1", "gene_name": "Vkorc1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALVLMTSSIVSVVGSLYLAYILYFVLKEFCIICVTTYVLNFLLLIINYKRLVYLNEAWKRQLQPKED", "length": 176 }, "evidence": [ { "id": "F1P573", "url": "https://omabrowser.org/oma/group/F1P573/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N0U8-1", "protein_name": "Vitamin K epoxide reductase complex subunit 1-like protein 1", "gene_name": "VKORC1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD", "length": 176 }, "evidence": [ { "id": "F1P573", "url": "https://omabrowser.org/oma/group/F1P573/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "vitamin-K-epoxide reductase (warfarin-sensitive) activity", "id": "GO:0047057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047057", "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vitamin K metabolic process", "id": "GO:0042373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042373", "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "F1P573", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-6806647", "name": "VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-6806366" ], "output_participant_list": [ "R-ALL-6806362" ], "enzyme_list": [ "F1P573-1" ], "evidence": [ { "id": "R-GGA-6806647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6806647" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6806362", "participant_name": "MK4 [endoplasmic reticulum lumen]", "crossref": [ { "id": "78277", "database": "ChEBI", "url": "" }, { "id": "HMDB0030017", "database": "HMDB Metabolite", "url": "" }, { "id": "HMDB0030020", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000003874199", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-6806366", "participant_name": "MK4 epoxide [endoplasmic reticulum lumen]", "crossref": [ { "id": "90152", "database": "ChEBI", "url": "" }, { "id": "ZINC000038842630", "database": "ZINC", "url": "" }, { "id": "ZINC000103579157", "database": "ZINC", "url": "" }, { "id": "ZINC000103579161", "database": "ZINC", "url": "" }, { "id": "ZINC000038842629", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1P573", "gene_name": "VKORC1L1", "activity": [ { "ec_number": "1.17.4.4", "activity": "phylloquinol + [protein]-disulfide = phylloquinone + [protein]-dithiol.", "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ] }, { "ec_number": "1.17.4.4", "activity": "", "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P573-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 176, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P573-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P573" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P573" }, { "id": "SM00756", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00756" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vitamin K epoxide reductase", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 160, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.17.4.4", "ec_name": "phylloquinol + [protein]-disulfide = phylloquinone + [protein]-dithiol.", "evidence": [ { "id": "1.17.4.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.4" }, { "id": "1.17.4.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.17.4.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5E7-1", "uniprot_ac": "A0A8V0Z5E7", "uniprot_id": "A0A8V0Z5E7_CHICK", "mass": { "chemical_mass": 72018.0, "monoisotopic_mass": 72018.0 }, "refseq": {}, "gene_names": [ { "name": "SLC6A14", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5E7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005957", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005957", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11501", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11501", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857521", "url": "https://www.ncbi.nlm.nih.gov/gene/100857521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857521", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857521", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APNWGPY", "url": "https://omabrowser.org/oma/group/APNWGPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5E7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5F2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C8K0", "url": "https://www.orthodb.org/?gene=E1C8K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8K0", "url": "https://www.uniprot.org/uniprotkb/E1C8K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8K0-1", "url": "https://www.uniprot.org/uniprotkb/E1C8K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGDRWAGNCSCGRKEDFNLSNEKDAHASDNDENSDRGNWSNKADYLLSMVGYAVGLGNVWRFPYLTYQNGGGAFLIPYTLMLALAGLPLFFMECSLGQFASLGPISIWRILPLFQGVGVTMVIISTFVAIYYNVIIAYALYYLFASFQKVLPWSDCFSWADEFCSKTRLVNDCSAVLDGQIIHANYSFIASNNLTCLNDTINYKPVQFPSEQYWNKVALQRSSGLDETGNIVWYLALCLLLSWMIVGAALFKGIKSSGKVVYFTALFPYVILLILLVRGATLEGALDGIEYYIGKQSNITKLMEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFHNNCYSDAIFVCVTNCLTSVFAGFAIFSVLGHMAFVLKRPVSEVVDSGFDLAFVAYPEALSKLPVSPLWSFLFFFMLLLLGLDSQFATIETLTTTIQDIYPKMMKKLRIPITLGVCVLLFFLGLICVTQAGIYWVNLIDHFCAGWGILFAAVLEIIGIVYIYGGNRFIEDIEMMIGKKSCFFWMWWRMCWFFITPVLLVAILVWSLVTFSAPTYGSVLYPTWGTAVGWCMIIFCVIWIPIVAVVKILKAEGNLFQRIASCCRPTANWGPYLECHRGERYSHVVTPKKEKEHEIPTVSGFTYFRE", "length": 640, "header": "tr|A0A8V0Z5E7-1|A0A8V0Z5E7_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A14 PE=1 SV=1 CANONICAL=A0A8V0Z5E7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7/entry#A0A8V0Z5E7-1", "sequence": { "sequence": "MKGDRWAGNCSCGRKEDFNLSNEKDAHASDNDENSDRGNWSNKADYLLSMVGYAVGLGNVWRFPYLTYQNGGGAFLIPYTLMLALAGLPLFFMECSLGQFASLGPISIWRILPLFQGVGVTMVIISTFVAIYYNVIIAYALYYLFASFQKVLPWSDCFSWADEFCSKTRLVNDCSAVLDGQIIHANYSFIASNNLTCLNDTINYKPVQFPSEQYWNKVALQRSSGLDETGNIVWYLALCLLLSWMIVGAALFKGIKSSGKVVYFTALFPYVILLILLVRGATLEGALDGIEYYIGKQSNITKLMEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFHNNCYSDAIFVCVTNCLTSVFAGFAIFSVLGHMAFVLKRPVSEVVDSGFDLAFVAYPEALSKLPVSPLWSFLFFFMLLLLGLDSQFATIETLTTTIQDIYPKMMKKLRIPITLGVCVLLFFLGLICVTQAGIYWVNLIDHFCAGWGILFAAVLEIIGIVYIYGGNRFIEDIEMMIGKKSCFFWMWWRMCWFFITPVLLVAILVWSLVTFSAPTYGSVLYPTWGTAVGWCMIIFCVIWIPIVAVVKILKAEGNLFQRIASCCRPTANWGPYLECHRGERYSHVVTPKKEKEHEIPTVSGFTYFRE", "length": 640, "header": "tr|A0A8V0Z5E7-1|A0A8V0Z5E7_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A14 PE=1 SV=1 CANONICAL=A0A8V0Z5E7-1" }, "locus": { "chromosome": "4", "start_pos": 3012173, "end_pos": 2998661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048264.1", "url": "https://www.ensembl.org/id/ENSGALT00010048264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028457.1", "url": "https://www.ensembl.org/id/ENSGALP00010028457.1" } ] } }, { "isoform_ac": "A0A8V0Z5F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7/entry#A0A8V0Z5F2-1", "sequence": { "sequence": "MKGDRWAGNCSCGRKEDFNLSNEKDAHASDNDENSDRGNWSNKADYLLSMVGYAVGLGNVWRFPYLTYQNGGGAFLIPYTLMLALAGLPLFFMECSLGQFASLGPISIWRILPLFQGVGVTMVIISTFVAIYYNVIIAYALYYLFASFQKVLPWSDCFSWADEFCSKTRLVNDCSAVLDGQIIHANYSFIASNNLTCLNDTINYKPVQFPSEQYWNKVALQRSSGLDETGNIVWYLALCLLLSWMIVGAALFKGIKSSGKVVYFTALFPYVILLILLVRGATLEGALDGIEYYIGKQSNITKLMEVWKDAATQIFYSLSVAWGGLVALSSYNKFHNNCYSDAIFVCVTNCLTSVFAGFAIFSVLGHMAFVLKRPVSEVVDSGFDLAFVAYPEALSKLPVSPLWSFLFFFMLLLLGLDSQFATIETLTTTIQDIYPKMMKKLRIPITLGVCVLLFFLGLICVTQAGIYWVNLIDHFCAGWGILFAAVLEIIGIVYIYGGNRFIEDIEMMIGKKSCFFWMWWRMCWFFITPVLLVAILVWSLVTFSAPTYGSVLYPTWGTAVGWCMIIFCVIWIPIVAVVKILKAEGNLFQRIASCCRPTANWGPYLECHRGERYSHVVTPKKEKEHEIPTVSGFTYFRE", "length": 638, "header": "tr|A0A8V0Z5F2-1|A0A8V0Z5F2_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A14 PE=1 SV=1 CANONICAL=A0A8V0Z5E7-1" }, "locus": { "chromosome": "4", "start_pos": 3012173, "end_pos": 2998661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048272.1", "url": "https://www.ensembl.org/id/ENSGALT00010048272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028462.1", "url": "https://www.ensembl.org/id/ENSGALP00010028462.1" } ] } }, { "isoform_ac": "E1C8K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7/entry#E1C8K0-1", "sequence": { "sequence": "MGMLSLPGFLSCGKKKDFNLSNEKDAHASDNDENSDRGNWSNKADYLLSMVGYAVGLGNVWRFPYLTYQNGGGAFLIPYTLMLALAGLPLFFMECSLGQFASLGPISIWRILPLFQGVGVTMVIISTFVAIYYNVIIAYALYYLFASFQKVLPWSDCFSWADEFCSKTRLVNDCSAVLDGQIIHANYSFIASNNLTCLNDTINYKPVQFPSEQYWNKVALQRSSGLDETGNIVWYLALCLLLSWMIVGAALFKGIKSSGKVVYFTALFPYVILLILLVRGATLEGALDGIEYYIGKQSNITKLMEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFHNNCYSDAIFVCVTNCLTSVFAGFAIFSVLGHMAFVLKRPVSEVVDSGFDLAFVAYPEALSKLPVSPLWSFLFFFMLLLLGLDSQFATIETLTTTIQDIYPKMMKKLRIPITLGVCVLLFFLGLICVTQAGIYWVNLIDHFCAGWGILFAAVLEIIGIVYIYGGNRFIEDIEMMIGKKSCFFWMWWRMCWFFITPVLLVAILVWSLVTFSAPTYGSVLYPTWGTAVGWCMIIFCVIWIPIVAVVKILKAEGNLFQRIASCCRPTANWGPYLECHRGERYSHVVTPKKEKEHEIPTVSGFTYFRE", "length": 640, "header": "tr|E1C8K0-1|A0A8V0Z5E7_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A14 PE=1 SV=2 CANONICAL=A0A8V0Z5E7-1" }, "locus": { "chromosome": "4", "start_pos": 3012173, "end_pos": 2999163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048257.1", "url": "https://www.ensembl.org/id/ENSGALT00010048257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028454.1", "url": "https://www.ensembl.org/id/ENSGALP00010028454.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857521", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-GGA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W4T9-1", "protein_name": "Transporter", "gene_name": "SLC6A14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRLKCPSFFKCRGKEKVTASSEDFHIRENDENQDRGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYNNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSKLPWENCSYWADENCSRSPIVTHCNVSIRSNEIFQMNKSWVDANNLTCINGSEVYQPGQLPSEQYWNKVALQRSSGMDETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTAIFPYVVLLILLIRGATLDGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELIGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVITPILLIAILIWSLVQFHRPDYAKIPYPDWGVALGWCMIIFCIIWIPIMAIIKIIQAEGNIFQRIVSCCRPASNWGPYLERHRGERYKNMVDPKKETDHEIPTVSGSRKPE", "length": 639 }, "evidence": [ { "id": "A0A8V0Z5E7", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6NN04-1", "protein_name": "Transporter", "gene_name": "slc6a14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDYSLKNIRGVLFKNSVGDEQDKDKSDKAEHVVQNDENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWSIKNCNTTASNISTAAVNVSCGQISGQSLSEKYWDEVALQRSSSMDETGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAIFSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSLYTFTSPTYSSVAYPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGPYLECHRGERYGTRGETDPNIFVISNKVSTRL", "length": 614 }, "evidence": [ { "id": "A0A8V0Z5E7", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JMA9-1", "protein_name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "gene_name": "Slc6a14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRLKCPNFFKCRQKEKVTASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISVFVAIYYNVIIAYSLYYLFASFQSVLPWANCSSWADENCSRTPIVTGCNVSIGAGEMFMNISWVNTNNLTCLNGSEVFRPGQLPSEQYWDKVTLQRSSGMDETGVVVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPAGPFWSILFFFMLLTLGLDSQFASIETITTTFQDLFPKAMKRMRVPITLGCCLILFLLGLLCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVITPILLSAILVWSLVKFHRPDYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVQAEGNILQRIISCCRPASNWGPYLEKHRGERYRDMAEPAKETDHEIPTISGSTKPE", "length": 638 }, "evidence": [ { "id": "A0A8V0Z5E7", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UN76-1", "protein_name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "gene_name": "SLC6A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE", "length": 642 }, "evidence": [ { "id": "A0A8V0Z5E7", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "(R)-carnitine transmembrane transporter activity", "id": "GO:1901235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "alanine transmembrane transporter activity", "id": "GO:0022858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022858", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "beta-alanine transmembrane transporter activity", "id": "GO:0001761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "neutral, basic amino acid:sodium:chloride symporter activity", "id": "GO:0015374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "branched-chain amino acid:sodium symporter activity", "id": "GO:0015657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "(R)-carnitine transmembrane transport", "id": "GO:1902270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" }, { "name": "beta-alanine transport", "id": "GO:0001762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, 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"start_pos": 199, "end_pos": 201 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5U1-1", "uniprot_ac": "A0A8V0Z5U1", "uniprot_id": "A0A8V0Z5U1_CHICK", "mass": { "chemical_mass": 74587.0, "monoisotopic_mass": 74587.0 }, "refseq": {}, "gene_names": [ { "name": "MGAT4B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ] } ], "protein_names": [ { "name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MGAT4B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1", "locus": { "chromosome": "13", "start_pos": 13110807, "end_pos": 13070292, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016927", "url": "https://www.ensembl.org/id/ENSGALG00010016927" } ] } } ], "crossref": [ { "id": "A0A8V0Z5U1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5U1", "database": "AlphaFoldDB", "categories": [] }, { "id": "416285", "url": "https://www.ncbi.nlm.nih.gov/gene/416285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FLMFHND", "url": "https://omabrowser.org/oma/group/FLMFHND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS42", "url": "https://www.orthodb.org/?gene=A0A8V0YS42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYW5", "url": "https://www.orthodb.org/?gene=A0A8V0YYW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YYZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0B9", "url": "https://www.orthodb.org/?gene=A0A8V0Z0B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0C4", "url": "https://www.orthodb.org/?gene=A0A8V0Z0C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5U1", "url": "https://www.orthodb.org/?gene=A0A8V0Z5U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-975577", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975577", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YS42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIKLLQFHDSKLQRKGSERSIQHPCSSASSPRPPSAGKCLKIFAESAAPKARSSEVLLLPKLCIVAAKPCWDAAPVPTDHNRGCWWFSRGNRYPNHRPTTTQGAAAGWEGRVCPCAELQRAGAGAFQRLLERDPLDVQGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 653, "header": "tr|A0A8V0Z5U1-1|A0A8V0Z5U1_CHICK Isoform 1 of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0YS42-1", "sequence": { "sequence": "MLSLPSAGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 521, "header": "tr|A0A8V0YS42-1|A0A8V0Z5U1_CHICK Computationally mapped isoform of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13097528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040880.1", "url": "https://www.ensembl.org/id/ENSGALT00010040880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023844.1", "url": "https://www.ensembl.org/id/ENSGALP00010023844.1" } ] } }, { "isoform_ac": "A0A8V0YYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0YYW5-1", "sequence": { "sequence": "MHVSTMLCVSPSSLRRNCSVCDRPQLHKSKFGGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 546, "header": "tr|A0A8V0YYW5-1|A0A8V0Z5U1_CHICK Computationally mapped isoform of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13097366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040874.1", "url": "https://www.ensembl.org/id/ENSGALT00010040874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023838.1", "url": "https://www.ensembl.org/id/ENSGALP00010023838.1" } ] } }, { "isoform_ac": "A0A8V0YYZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0YYZ1-1", "sequence": { "sequence": "MRPQGFVVPWCGEDPSFLQPFMRTKYSSSNQGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 545, "header": "tr|A0A8V0YYZ1-1|A0A8V0Z5U1_CHICK Computationally mapped isoform of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13073435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040898.1", "url": "https://www.ensembl.org/id/ENSGALT00010040898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023863.1", "url": "https://www.ensembl.org/id/ENSGALP00010023863.1" } ] } }, { "isoform_ac": "A0A8V0Z0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0Z0B9-1", "sequence": { "sequence": "MRLRSGTALTLLLGCLCALLSLSWYGAFGGHKGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 499, "header": "tr|A0A8V0Z0B9-1|A0A8V0Z5U1_CHICK Computationally mapped isoform of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13074652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040883.1", "url": "https://www.ensembl.org/id/ENSGALT00010040883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023847.1", "url": "https://www.ensembl.org/id/ENSGALP00010023847.1" } ] } }, { "isoform_ac": "A0A8V0Z0C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0Z0C4-1", "sequence": { "sequence": "MFISDFFCPGQLEGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 527, "header": "tr|A0A8V0Z0C4-1|A0A8V0Z5U1_CHICK Computationally mapped isoform of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13073988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040888.1", "url": "https://www.ensembl.org/id/ENSGALT00010040888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023852.1", "url": "https://www.ensembl.org/id/ENSGALP00010023852.1" } ] } }, { "isoform_ac": "A0A8V0Z5U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1/entry#A0A8V0Z5U1-1", "sequence": { "sequence": "MGIKLLQFHDSKLQRKGSERSIQHPCSSASSPRPPSAGKCLKIFAESAAPKARSSEVLLLPKLCIVAAKPCWDAAPVPTDHNRGCWWFSRGNRYPNHRPTTTQGAAAGWEGRVCPCAELQRAGAGAFQRLLERDPLDVQGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSEKQALRDINRTWSSLSDETKLKLWNITNKNVLHLPTIFHHLPHLLSKENSLQPAVHVGQGRTGVSVVMGIPSVKREVHSYLTDTLSSLISELTQQEKEDSVIVVLIAETDTQYTAGVAENIKNLFPKEIHSGLLEVISPSPHFYPDFSHLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYKDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPTAGDFIRFRFFKPLRIERFFFRSGNIEHPEDKLFNTTVEVLPFDSLQSDKETLQEGRGTAVRYHRTADGYIQIGSFSKGVAEGEVDPSFGPLEAIRLSIQTDSPVWIILSEIFIKKAE", "length": 653, "header": "tr|A0A8V0Z5U1-1|A0A8V0Z5U1_CHICK Isoform 1 of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B OS=Gallus gallus OX=9031 GN=MGAT4B PE=4 SV=1 CANONICAL=A0A8V0Z5U1-1" }, "locus": { "chromosome": "13", "start_pos": 13109801, "end_pos": 13071894, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040901.1", "url": "https://www.ensembl.org/id/ENSGALT00010040901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023865.1", "url": "https://www.ensembl.org/id/ENSGALP00010023865.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-975577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975577", "resource": "Reactome", "description": "N-Glycan antennae elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "B2GV39-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "Mgat4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSERQALRDGEGNRTWGRLTEDPRLKPWNVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDTQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERPGMAFSLLGLDRGSWAVLRLTGPLGVCRFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFYKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD", "length": 576 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S444-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "MGAT4B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDVYQREFLALRDRLRAAEQESLKRSKELNLVLDEIKRAVSERQALRDGDSNRTWGRLTEDPRLKPWNASQKHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDPQYTSLVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSDKEALQEGRSATLRYPRSPDGYLQIGTFYKGVAQGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD", "length": 548 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6GMK0-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "mgat4bQ9UQ53", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRLRNGTFLTVLLFGLCGLISLSWYTAFSNSKGNVVDIYQREFLALRDRLHSAEQENLKRSKELNLVLDEIKRAIAEKQALRDINRTWSSLSDETKLKLWNVTSSKNVLQLPSIFHHLPHLLAKESSLQPAVHIGQGRTGVSIVLGVPSVKREVHSYLTDTLSSLMTELSPAEKEDCVIVVFIAETDQQYANSVADNLKRLFPGEIQSGLLEIISPSVHFYPDFSHLKESFGDPKERVRWRTKQNLDYCFLMMYAQTKGNYYVQLEDDIVARPNYFTTMKNFALQQPSEEWMILEFSQLGFIGKMFKSLDLPLIVEFMLMFYKDKPIDWLLDHIMWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKQTLHKGHANPLAEVTTSLKTYQHFTLEKAYLGEDFFWAFTPVAGDFIRIRFFTPVRVERYFFRSGNIEHPGDKLFNTTVEVLPFDNIQSEKEALKEGREKTPKYQRTEDGFIRIGKFENGIAEGEVDASFGPLEALRLSVLTDSPVWVILSEIFIKKAE", "length": 547 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q812F8-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "Mgat4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSERQALRDGEGNRTWGRLTEDPRLKPWNVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDPQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFYKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD", "length": 548 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQ53-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "MGAT4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDVYQREFLALRDRLHAAEQESLKRSKELNLVLDEIKRAVSERQALRDGDGNRTWGRLTEDPRLKPWNGSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDSQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKQALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSDKEALQEGRTATLRYPRSPDGYLQIGSFYKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD", "length": 548 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUH4-1", "protein_name": "2.4.1.145", "gene_name": "Mgat4a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKIRQRNCMLIVTALVLAPCIVILMVMGPELSTEQSLTQRLAECHMRLQYLESMYRARQEDVALLSQYLGQLQIVNVTGASAPPPPPPLPVVNLLDGLSPEARQLLRNASHISKGGSANGSMARSQNIRLPNAYHFLPHLLDDAGSLRPAYLQSKGRSDVSIVLGVPTVRREKQSYLLGTLHNLIENMNDEEQNETLIIVYIGETDMESVQLIARQIESSFDQHVESGLIDIIAPAPSYYPNFERLRITLNDPLERVKWRSKQNLDFAYLMAYAHSKGTFYVQLEDDILTKRQFITTMKKFALIKSALTKPDQPEWFVLDFCQLGFIGKMFKSAELPYLITYFQMFYNDKPVDWLLTYFIESKVCRTDKDQKHCNAEKAKYWQHFRKSLFQHIGTSSSLKGKVQKLKDKQFGSKVPQYYAHTHNPPALVKSNIAPYKNYLLQRAYRGESYFWGLLPQPGDLVQIIFERPTQLRHYLFRSGNSEHPSDRFYNTTVELLPADTLSENSSVWSSYNTTTDGYLVVGSFDSMGVAEGLLDAKIGAIKELRLHVHSDSENWALLSEIELQEWGSDSKSEDNAAKPRYVGGS", "length": 587 }, "evidence": [ { "id": "A0A8V0Z5U1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5U1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" }, { "name": "alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0008454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" }, { "id": "PF23524", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 A/B/C C-terminal", "eco_id": "ECO_0000259", "start_pos": 506, "end_pos": 646, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U1" }, { "id": "PF04666", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 conserved region", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 492, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 570, "end_pos": 572 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z679-1", "uniprot_ac": "A0A8V0Z679", "uniprot_id": "A0A8V0Z679_CHICK", "mass": { "chemical_mass": 39535.0, "monoisotopic_mass": 39535.0 }, "refseq": { "ac": "XP_015140913", "name": "PDZ and LIM domain protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" }, "gene_names": [ { "name": "PDLIM3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679" } ] }, { "name": "ALP", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "name": "PDLIM3", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "name": "SkALP", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "name": "SmALP", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "name": "p36-ALP", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "name": "p40-ALP", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] } ], "protein_names": [ { "name": "PDZ and LIM domain protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679/entry#names_and_taxonomy" } ] }, { "name": "PDZ and LIM domain protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140913.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913" } ] }, { "annotation": "May play a role in the organization of actin filament arrays within muscle cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YSJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ5#function" }, { "database": "UniProtKB", "id": "ARBA00037484", "url": "https://www.uniprot.org/uniprotkb/ARBA00037484#function" }, { "database": "UniProtKB", "id": "A0A8V0Z679", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679#function" }, { "database": "UniProtKB", "id": "A0A8V0Z686", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z686#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z679", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDLIM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679", "locus": { "chromosome": "4", "start_pos": 60580166, "end_pos": 60602662, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016991", "url": "https://www.ensembl.org/id/ENSGALG00010016991" } ] } } ], "crossref": [ { "id": "A0A8V0Z679", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z679", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414873", "url": "https://www.ncbi.nlm.nih.gov/gene/414873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YSJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z679", "url": "https://www.orthodb.org/?gene=A0A8V0Z679", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z686", "url": "https://www.orthodb.org/?gene=A0A8V0Z686", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15936", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15936", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YSJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z679", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z679-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z686", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z686", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z686-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z686-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKASTANLCPGDIIVAINGLSTENMTHNDAQERIKAAAHQLSLRIERAETKLWSPQVSEDGKANPYKINLEAEPQDINYFEHRHNIRPKPFILPGRSSGCSTPSGIDCGSGRSTPSSISTVSSICPTELKAVSRMAPNVPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPVMSDPAPTAVPQSDVYRMLHSNQEEPSQPRQSGSFKVLQNLVSEEDGRPVGTRSVKAPVTKIPTGLPGAQKVPQCDKCGSGILGTVVKARDKYRHPECFVCSDCNLNLKQKGYFFVEGQLYCEAHARARMRPPEGYEAVTVYPKC", "length": 363, "header": "tr|A0A8V0Z679-1|A0A8V0Z679_CHICK Isoform 1 of PDZ and LIM domain protein 3 OS=Gallus gallus OX=9031 GN=PDLIM3 PE=4 SV=1 CANONICAL=A0A8V0Z679-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YSJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679/entry#A0A8V0YSJ5-1", "sequence": { "sequence": "MPQNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKASTANLCPGDIIVAINGLSTENMTHNDAQERIKAAAHQLSLRIERAETKLWSPQVSEDGKANPYKINLEAEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSSSYNSPIGLYSSGNIQDALHGQLRSLIPNASQNGCSTPSGIDCGSGRSTPSSISTVSSICPTELKAVSRMAPNVPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPVMSDPAPTAVPQSDVYRMLHSNQEEPSQPRQSGSFKVLQNLVSEEDGRPVGTRSVKAPVTKIPTGLPGAQKVPQCDKCGSGILGTVVKARDKYRHPECFVCSDCNLNLKQKGYFFVEGQLYCEAHARARMRPPEGYEAVTVYPKC", "length": 403, "header": "tr|A0A8V0YSJ5-1|A0A8V0Z679_CHICK Computationally mapped isoform of PDZ and LIM domain protein 3 OS=Gallus gallus OX=9031 GN=PDLIM3 PE=4 SV=1 CANONICAL=A0A8V0Z679-1" }, "locus": { "chromosome": "4", "start_pos": 60602488, "end_pos": 60581919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041032.1", "url": "https://www.ensembl.org/id/ENSGALT00010041032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023996.1", "url": "https://www.ensembl.org/id/ENSGALP00010023996.1" } ] } }, { "isoform_ac": "A0A8V0Z679-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679/entry#A0A8V0Z679-1", "sequence": { "sequence": "MPQNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKASTANLCPGDIIVAINGLSTENMTHNDAQERIKAAAHQLSLRIERAETKLWSPQVSEDGKANPYKINLEAEPQDINYFEHRHNIRPKPFILPGRSSGCSTPSGIDCGSGRSTPSSISTVSSICPTELKAVSRMAPNVPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPVMSDPAPTAVPQSDVYRMLHSNQEEPSQPRQSGSFKVLQNLVSEEDGRPVGTRSVKAPVTKIPTGLPGAQKVPQCDKCGSGILGTVVKARDKYRHPECFVCSDCNLNLKQKGYFFVEGQLYCEAHARARMRPPEGYEAVTVYPKC", "length": 363, "header": "tr|A0A8V0Z679-1|A0A8V0Z679_CHICK Isoform 1 of PDZ and LIM domain protein 3 OS=Gallus gallus OX=9031 GN=PDLIM3 PE=4 SV=1 CANONICAL=A0A8V0Z679-1" }, "locus": { "chromosome": "4", "start_pos": 60602488, "end_pos": 60581919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041038.1", "url": "https://www.ensembl.org/id/ENSGALT00010041038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024002.1", "url": "https://www.ensembl.org/id/ENSGALP00010024002.1" } ] } }, { "isoform_ac": "A0A8V0Z686-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z679/entry#A0A8V0Z686-1", "sequence": { "sequence": "MPQNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKASTANLCPGDIIVAINGLSTENMTHNDAQERIKAAAHQLSLRIERAETKLWSPQVSEDGKANPYKINLEAEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSSSYNSPIGLYSSGNIQDALHGQLRSLIPNASQNDPAPTAVPQSDVYRMLHSNQEEPSQPRQSGSFKVLQNLVSEEEIFWISDGRPVGTRSVKAPVTKIPTGLPGAQKVPQCDKCGSGILGTVVKARDKYRHPECFVCSDCNLNLKQKGYFFVEGQLYCEAHARARMRPPEGYEAVTVYPKC", "length": 321, "header": "tr|A0A8V0Z686-1|A0A8V0Z686_CHICK Computationally mapped isoform of PDZ and LIM domain protein 3 OS=Gallus gallus OX=9031 GN=PDLIM3 PE=1 SV=1 CANONICAL=A0A8V0Z679-1" }, "locus": { "chromosome": "4", "start_pos": 60602488, "end_pos": 60581919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041046.1", "url": "https://www.ensembl.org/id/ENSGALT00010041046.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024007.1", "url": "https://www.ensembl.org/id/ENSGALP00010024007.1" } 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"https://www.uniprot.org/uniprotkb/A0A8V0Z155-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z194", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z194", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z194-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z194-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSP7", "url": "https://www.uniprot.org/uniprotkb/E1BSP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSP7-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTAVKRVQSSPNLLASGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKGGDISKVYPSLLSYSVHNHNTSNELDYCSTYRQHLAVPNDSRRAISYKNGWQMTRQNAEVWSSTEETTSPKRKSRSCDDLLTDDRDSFPDAQAKSESMGSLLCEEDAKEVCSMNWASPYAPEGRGGGRARVRHRSAHDAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQNKGILQGWRESSTEEVPRDMVPTRISEFEKLIQKSKSMPNLGDEMLSNITLEPPKNGLCSQRRFSIESLLEEENEVRHPSQVQRSYKSKTLVPIHIEVTSDEPQRSHMDFSDSDQDGVVSDLSDFIQIEGSSFCSESDFDHYSFTSSESFYGSGHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERAKQEPAEDPRRQEAESGLSKIAFLVSPVPFRRKKSAAPKKQTEKTKRKSSVFEALDSALKDICDQIKAEKRRGSLPDNSILHRLITELLPDIPERNSSLTALKKSPMHQPFHPLPQDGATHCPLYQNDCGRLPLSASLQDMDTTNNNNQENDSALCFQDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1201, "header": "tr|A0A8V0Z6P7-1|A0A8V0Z6P7_CHICK Isoform 1 of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UI94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A3Q2UI94-1", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTAVKRVQSSPNLLASGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAPLPPPRKESFRKARVTNHKNGINLQTVTTEPDKHLPTDTGYYTNEKSAQKIMSSQISNTNVSYVQTITRPLTTISSVGTSTVAGISATLHQGQMQKSQKRRVSTLKLTRTQESASSVHCNIQQQPKPVEVPIFSQRPVSPACNPMAEMHTASLSIQIAPIPDNNAEPETQEHPPSISPDTSKMSSKDVGQKSTVLPSSQAAECHVLGNQKVTAPVMEVNASQTHRQTATEASPLPLPPPVVPVNRASFSPDSGTHLVPYSLPTLDDFSRFYKTPALSQFSYKCPFLASENTIHKNETASVSTDSAMSECSSRTMSESSTAILDELQSCSYDTTDCSETPSPTLSQMSAVSDGTTLTNTAATSNAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1040, "header": "tr|A0A3Q2UI94-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041281.1", "url": "https://www.ensembl.org/id/ENSGALT00010041281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024169.1", "url": "https://www.ensembl.org/id/ENSGALP00010024169.1" } ] } }, { "isoform_ac": "A0A8V0YT10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0YT10-1", "sequence": { "sequence": "MNTGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVELSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKLPFQALSPPPRYHFPSWSPNDQKTLQDATSDSFSRMDCFSPSSSCILPPPQFPDSFLCDLEELSSFALTTSQSLASSPNSSIHQVKENDFIPNTEISLSSTTALPRSSLVSASISPSASSSHDITHKHESNNTELRKDRDLRTEEPSKSLKTPRDLSDTITEDEHVSSTCNIPLLHKCSSLSTVLDASAENEDEICTADLSVDLGDQSEPQELDCYRESEDTTEELIKLYIEEDLIHDNLEFPIGSRGDSIVCCEGYTSPSIDKTALLSTKTSEESDTPFHLHSNLPFHSASTPASHSVHTTSHSSASLSPPLLSKLLHEQEKESLKANLKREIFVMGKPPRSPVMTKRSCSSPVRGHSYSHRPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1007, "header": "tr|A0A8V0YT10-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041294.1", "url": "https://www.ensembl.org/id/ENSGALT00010041294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024180.1", "url": "https://www.ensembl.org/id/ENSGALP00010024180.1" } ] } }, { "isoform_ac": "A0A8V0YT14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0YT14-1", "sequence": { "sequence": "MNTGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQLGNQKVTAPVMEAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 657, "header": "tr|A0A8V0YT14-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041300.1", "url": "https://www.ensembl.org/id/ENSGALT00010041300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024185.1", "url": "https://www.ensembl.org/id/ENSGALP00010024185.1" } ] } }, { "isoform_ac": "A0A8V0YZV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0YZV3-1", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTAVKRVQSSPNLLASGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 661, "header": "tr|A0A8V0YZV3-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041312.1", "url": "https://www.ensembl.org/id/ENSGALT00010041312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024195.1", "url": "https://www.ensembl.org/id/ENSGALP00010024195.1" } ] } }, { "isoform_ac": "A0A8V0Z155-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0Z155-1", "sequence": { "sequence": "MCTRSIEGTHSAPQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 605, "header": "tr|A0A8V0Z155-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60668521, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041265.1", "url": "https://www.ensembl.org/id/ENSGALT00010041265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024158.1", "url": "https://www.ensembl.org/id/ENSGALP00010024158.1" } ] } }, { "isoform_ac": "A0A8V0Z194-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0Z194-1", "sequence": { "sequence": "MSVTLTAVKRVQSSPNLLASAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 653, "header": "tr|A0A8V0Z194-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60684425, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041319.1", "url": "https://www.ensembl.org/id/ENSGALT00010041319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024199.1", "url": "https://www.ensembl.org/id/ENSGALP00010024199.1" } ] } }, { "isoform_ac": "A0A8V0Z6P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0Z6P2-1", "sequence": { "sequence": "MNTGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKVDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKTPVLTEMIPSNPDDGTDIWLSSLLISQLSVMLIYLNSHVFLIF", "length": 617, "header": "tr|A0A8V0Z6P2-1|A0A8V0Z6P2_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60628999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041270.1", "url": "https://www.ensembl.org/id/ENSGALT00010041270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024161.1", "url": "https://www.ensembl.org/id/ENSGALP00010024161.1" } ] } }, { "isoform_ac": "A0A8V0Z6P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0Z6P7-1", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTAVKRVQSSPNLLASGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKGGDISKVYPSLLSYSVHNHNTSNELDYCSTYRQHLAVPNDSRRAISYKNGWQMTRQNAEVWSSTEETTSPKRKSRSCDDLLTDDRDSFPDAQAKSESMGSLLCEEDAKEVCSMNWASPYAPEGRGGGRARVRHRSAHDAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQNKGILQGWRESSTEEVPRDMVPTRISEFEKLIQKSKSMPNLGDEMLSNITLEPPKNGLCSQRRFSIESLLEEENEVRHPSQVQRSYKSKTLVPIHIEVTSDEPQRSHMDFSDSDQDGVVSDLSDFIQIEGSSFCSESDFDHYSFTSSESFYGSGHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERAKQEPAEDPRRQEAESGLSKIAFLVSPVPFRRKKSAAPKKQTEKTKRKSSVFEALDSALKDICDQIKAEKRRGSLPDNSILHRLITELLPDIPERNSSLTALKKSPMHQPFHPLPQDGATHCPLYQNDCGRLPLSASLQDMDTTNNNNQENDSALCFQDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1201, "header": "tr|A0A8V0Z6P7-1|A0A8V0Z6P7_CHICK Isoform 1 of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041276.1", "url": "https://www.ensembl.org/id/ENSGALT00010041276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024166.1", "url": "https://www.ensembl.org/id/ENSGALP00010024166.1" } ] } }, { "isoform_ac": "A0A8V0Z6S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#A0A8V0Z6S6-1", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTAVKRVQSSPNLLASGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 676, "header": "tr|A0A8V0Z6S6-1|A0A8V0Z6S6_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=1 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041309.1", "url": "https://www.ensembl.org/id/ENSGALT00010041309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024192.1", "url": "https://www.ensembl.org/id/ENSGALP00010024192.1" } ] } }, { "isoform_ac": "E1BSP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7/entry#E1BSP7-1", "sequence": { "sequence": "MNTGSDSQSPDSAWRSYNDGSRETLNGDISSSSLTAKGFRSVRPNLQDKKSPTQAQITVNGNSGTAASPVSHFQRPFSPSSAYSPPASLNSNLVIMQHGRMMESTETYSQHVQTVGSSTTTSTIPICKSLEEEKKITVIKAPHYAGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTAYSYSTGGYSPSFSAQAHPAAKTQTYRPLSKSASDSGSDAFKVSSPLPPPHVPPPVPPHRLRERSIPEKNDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILEHERPASLYHHSSTDRGLDRPSSSASTASDYRKRRKSEPAVSHQRAHSDQNANRPSPGRTDMQGPYTTLRKPLTSSSPSSPSRAKGGDISKVYPSLLSYSVHNHNTSNELDYCSTYRQHLAVPNDSRRAISYKNGWQMTRQNAEVWSSTEETTSPKRKSRSCDDLLTDDRDSFPDAQAKSESMGSLLCEEDAKEVCSMNWASPYAPEGRGGGRARVRHRSAHDAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQNKGILQGWRESSTEEVPRDMVPTRISEFEKLIQKSKSMPNLGDEMLSNITLEPPKNGLCSQRRFSIESLLEEENEVRHPSQVQRSYKSKTLVPIHIEVTSDEPQRSHMDFSDSDQDGVVSDLSDFIQIEGSSFCSESDFDHYSFTSSESFYGSGHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERAKQEPAEDPRRQEAESGLSKIAFLVSPVPFRRKKSAAPKKQTEKTKRKSSVFEALDSALKDICDQIKAEKRRGSLPDNSILHRLITELLPDIPERNSSLTALKKSPMHQPFHPLPQDGATHCPLYQNDCGRLPLSASLQDMDTTNNNNQENDSALCFQDQETPGNYSAFTDVGRCTPRDRRGTPDKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLSPPEKAQPARPPPPAQIGEIGEAIAKYNFSADTNVELSLRKGDRVVLLKRVDQNWYEGKIPGTNRQGIFPVSYVEVIKKNASKSADDYPDPPIPQSYSSDRIHNLSSTKPQRPVLAHENIHSGGEPFQALYNYTPRNEDELELREGDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1170, "header": "tr|E1BSP7-1|A0A8V0Z6P7_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 2 OS=Gallus gallus OX=9031 GN=SORBS2 PE=1 SV=4 CANONICAL=A0A8V0Z6P7-1" }, "locus": { "chromosome": "4", "start_pos": 60691291, "end_pos": 60617354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041288.1", "url": "https://www.ensembl.org/id/ENSGALT00010041288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024175.1", "url": "https://www.ensembl.org/id/ENSGALP00010024175.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422719", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422719", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1100, "end_pos": 1102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" }, { "start_pos": 942, "end_pos": 944, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 963, "end_pos": 1022, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z6P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P7" }, { "id": "PS50831", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SoHo", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 230, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 1100, "end_pos": 1102 }, { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 1152, "end_pos": 1154 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 873, "end_pos": 875 }, { "start_pos": 928, "end_pos": 930 }, { "start_pos": 942, "end_pos": 944 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z754-1", "uniprot_ac": "A0A8V0Z754", "uniprot_id": "A0A8V0Z754_CHICK", "mass": { "chemical_mass": 30834.0, "monoisotopic_mass": 30834.0 }, "refseq": {}, "gene_names": [ { "name": "UBFD1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754" } ] } ], "protein_names": [ { "name": "Ubiquitin family domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z754", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754", "locus": { "chromosome": "14", "start_pos": 6925180, "end_pos": 6931043, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017211", "url": "https://www.ensembl.org/id/ENSGALG00010017211" } ] } } ], "crossref": [ { "id": "A0A8V0Z754", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z754", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTC9", "url": "https://www.orthodb.org/?gene=A0A8V0YTC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z754", "url": "https://www.orthodb.org/?gene=A0A8V0Z754", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16470", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16470", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16470:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16470:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25343", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25343", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YTC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z754", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z754-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATPSAAAEGAAEPGMEAEALGCGGEGGSPRGEGCRAAPPGAVSNGSDAESGQELVELRVIWNKNKYDVKFRLDSTGADLKQKIHSLTGLPPAMQKVMFKGLLPEEKTLREIKVTNGAKIMVVGSTINDVLAVNTPKDAAQQEGKAEESKKEPLCRQKQHRKVLDKGKPDDVMPSIKGVQEHLPAVPLSGMYNKSGGKVRLTFKLEQDQLWIGTKERTEKLPMASIKNVVSEPIEGHEDYHMMGKKCCTFKLLSAGGSWSSLCSHVWFLITDKRKRPLLDMIQ", "length": 284, "header": "tr|A0A8V0Z754-1|A0A8V0Z754_CHICK Isoform 1 of Ubiquitin family domain containing 1 OS=Gallus gallus OX=9031 GN=UBFD1 PE=1 SV=1 CANONICAL=A0A8V0Z754-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754/entry#A0A8V0YTC9-1", "sequence": { "sequence": "MEAEALGCGGEGGSPRGEGCRAAPPGAVSNGSDAESGQELVELRVIWNKNKYDVKFRLDSTGADLKQKIHSLTGLPPAMQKVMFKGLLPEEKTLREIKVTNGAKIMVVGSTINDVLAVNTPKDAAQQEGKAEESKKEPLCRQKFTFTQHRKVLDKGKPDDVMPSIKGVQEHLPAVPLSGMYNKSGGKVRLTFKLEQDQLWIGTKERTEKLPMASIKNVVSEPIEGHEDYHMMAFQLGPTEASYYWVYWVPNQYVDAIKDTVLGKWQYF", "length": 268, "header": "tr|A0A8V0YTC9-1|A0A8V0Z754_CHICK Computationally mapped isoform of Ubiquitin family domain containing 1 OS=Gallus gallus OX=9031 GN=UBFD1 PE=1 SV=1 CANONICAL=A0A8V0Z754-1" }, "locus": { "chromosome": "14", "start_pos": 6930835, "end_pos": 6925559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041496.1", "url": "https://www.ensembl.org/id/ENSGALT00010041496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024302.1", "url": "https://www.ensembl.org/id/ENSGALP00010024302.1" } ] } }, { "isoform_ac": "A0A8V0Z754-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754/entry#A0A8V0Z754-1", "sequence": { "sequence": "MAATPSAAAEGAAEPGMEAEALGCGGEGGSPRGEGCRAAPPGAVSNGSDAESGQELVELRVIWNKNKYDVKFRLDSTGADLKQKIHSLTGLPPAMQKVMFKGLLPEEKTLREIKVTNGAKIMVVGSTINDVLAVNTPKDAAQQEGKAEESKKEPLCRQKQHRKVLDKGKPDDVMPSIKGVQEHLPAVPLSGMYNKSGGKVRLTFKLEQDQLWIGTKERTEKLPMASIKNVVSEPIEGHEDYHMMGKKCCTFKLLSAGGSWSSLCSHVWFLITDKRKRPLLDMIQ", "length": 284, "header": "tr|A0A8V0Z754-1|A0A8V0Z754_CHICK Isoform 1 of Ubiquitin family domain containing 1 OS=Gallus gallus OX=9031 GN=UBFD1 PE=1 SV=1 CANONICAL=A0A8V0Z754-1" }, "locus": { "chromosome": "14", "start_pos": 6931035, "end_pos": 6926184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041498.1", "url": "https://www.ensembl.org/id/ENSGALT00010041498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024303.1", "url": "https://www.ensembl.org/id/ENSGALP00010024303.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4, "start_aa": "Thr", "end_pos": 4, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z754" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 124, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 4 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7F3-1", "uniprot_ac": "A0A8V0Z7F3", "uniprot_id": "A0A8V0Z7F3_CHICK", "mass": { "chemical_mass": 146517.0, "monoisotopic_mass": 146517.0 }, "refseq": { "ac": "XP_004936456", "name": "inverted formin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936456" }, "gene_names": [ { "name": "INF2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ] }, { "name": "INF2", "type": "synonym", "evidence": [ { "id": "XP_004936456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936456" } ] } ], "protein_names": [ { "name": "Inverted formin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3/entry#names_and_taxonomy" } ] }, { "name": "inverted formin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004936456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936456" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936456.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936456" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3", "locus": { "chromosome": "5", "start_pos": 51029087, "end_pos": 50990682, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017283", "url": "https://www.ensembl.org/id/ENSGALG00010017283" } ] } } ], "crossref": [ { "id": "cd22061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423492", "url": "https://www.ncbi.nlm.nih.gov/gene/423492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVCSQQY", "url": "https://omabrowser.org/oma/group/MVCSQQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTL1", "url": "https://www.orthodb.org/?gene=A0A8V0YTL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7D5", "url": "https://www.orthodb.org/?gene=A0A8V0Z7D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7E1", "url": "https://www.orthodb.org/?gene=A0A8V0Z7E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7F3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46345:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46345:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILRLIAHRCDSFLPALLGRDKQFTMSIKKEGAHKKWAALKEKLGPQDTDQSEANLENAEPELCIRLLQMPSVVNYSGLKKRLENSDDAWMVQFLELCGLDLLLEALDRLSGRGVARISDALLQLTCINCVRAVMNSHRGIEYIVSNEGYVRKLFQALDTTNVMVKKQVFELLAALCIYSSDGHGLALDALDHYKNVKNQQYRFSVIMNELSNTDNVPYMVTLLSAINAIILGKEDLRTRTQIRNEFIGLQLLDILDKLRDIEEEDLLIQCDTFEEFKIEDDEELLKICDGINMNDHHEVFSSLFNKVSRSPISIQLLSILQSLLYLEPSHHSSLLLWESLDAVVNRALLLANDIQGNTVEEVIERLLSIKKHPNKQKRAEKRLSGNANGGIQTEREPCTSAVQSLMGSPNPCKTPEAPSGPQACEEKTSSSQLSACFTSPQTSNPPPNAAPALPPPPPPPPPPPPPPLPSGPAAMPPTASVNFPPAPPLPGIPPPPPPLPGMAVIPPPPPLPGMAVIPPPPPPLPGMGGIPPPPPLPGMGGIPPPPPLPGLGGIPPPPPLPGLAGIPPPPPLPGMGGIPPPPPLSGMGGIPPPPPPLPGMAGDNIEAVVAPQFSCPLGFISPPRKAVKTPTMRMKKLNWQKLPSNVVRESHSMWASVSSSSEETIEPNYTSIEQLFCFPQPTPKEKTAAPVKAEPKEITFLDSKKSLNLNIFLKQFKCSNEEVAAMVQNGDRTKFDVEVLKQLLKLLPEKHEIENLKAFKEEKSKLANADQFYLLLLQIPSYQLRIECMLICEETTVVLDMIQPKAEAIRKACEDLLTSHRLPLFCKLILKVGNFLNYGSHTGDADGFKISTLLKLTETKANQTRITLLHHILEEVENSHTDLLELPEDLEYVSKAAGINLDIIRSESSANLKKLLELQRKVSSANDDVKQQYEKPIQDSIDASRKLEEDFETIDRKREELANYLCEDPTKLSLEDVFSTMKTFRDLFIRALKENKDRKEQAAKAEKRKKQLEEEEGKRQKGENGKVIKKGLVKQEDVCVIDALLADIRKGFTLRKTKNRHESDAPPKTLPAEIPEENRSGKSIKDPQAGGQQMDDKAKQNNGHPSDESTLSLADALPEMGRDVGDASAPNQALPENNAGGNLPRGSRTEGPLVNLVEADGAGQGAGMASLQPGLGSGAISFSAANIGANITFVSSSSGAALREQLNGSTSEEQDKKCPGDGLESCRLAQDIQLNQNGGNPSTPSTPCDGAHQADLKEMAKENEDPATDSLLDTSQEKSFSEEPATDSSCSATLPPGETHTDREKQRTSGKRRKKKRHSKSYSEVETDSGDYKTKKGCVVQ", "length": 1342, "header": "tr|A0A8V0Z7F3-1|A0A8V0Z7F3_CHICK Isoform 1 of Inverted formin 2 OS=Gallus gallus OX=9031 GN=INF2 PE=1 SV=1 CANONICAL=A0A8V0Z7F3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3/entry#A0A8V0YTL1-1", "sequence": { "sequence": "MILRLIAHRCDSFLPALLGRDKQFTMSIKKEGAHKKWAALKEKLGPQDTDQSEANLENAEPELCIRLLQMPSVVNYSGLKKRLENSDDAWMVQFLELCGLDLLLEALDRLSGRGVARISDALLQLTCINCVRAVMNSHRGIEYIVSNEGYVRKLFQALDTTNVMVKKQVFELLAALCIYSSDGHGLALDALDHYKNVKNQQYRFSVIMNELSNTDNVPYMVTLLSAINAIILGKEDLRTRTQIRNEFIGLQLLDILDKLRDIEEEDLLIQCDTFEEFKIEDDEELLKICDGINMNDHHEVFSSLFNKVSRSPISIQLLSILQSLLYLEPSHHSSLLLWESLDAVVNRALLLANDIQGNTVEEVIERLLSIKKHPNKQKRAEKRLSGNANGGIQTEREPCTSAVQSLMGSPNPCKTPEAPSGPQACEEKTSSSQLSACFTSPQTSNPPPNAAPALPPPPPPPPPPPPPPLPSGPAAMPPTASVNFPPAPPLPGIPPPPPPLPGMAVIPPPPPLPGMAVIPPPPPPLPGMGGIPPPPPLPGMGGIPPPPPLPGLGGIPPPPPLPGLAGIPPPPPLPGMGGIPPPPPLSGMGGIPPPPPPLPGMAGDNIEAVVAPQFSCPLGFISPPRKAVKTPTMRMKKLNWQKLPSNVVRESHSMWASVSSSSEETIEPNYTSIEQLFCFPQPTPKEKTAAPVKAEPKEITFLDSKKSLNLNIFLKQFKCSNEEVAAMVQNGDRTKFDVEVLKQLLKLLPEKHEIENLKAFKEEKSKLANADQFYLLLLQIPSYQLRIECMLICEETTVVLDMIQPKAEAIRKACEDLLTSHRLPLFCKLILKVGNFLNYGSHTGDADGFKISTLLKLTETKANQTRITLLHHILEEVENSHTDLLELPEDLEYVSKAAGINLDIIRSESSANLKKLLELQRKVSSANDDVKQQYEKPIQDSIDASRKLEEDFETIDRKREELANYLCEDPTKLSLEDVFSTMKTFRDLFIRALKENKDRKEQAAKAEKRKKQLEEEEGKRQKGENGKVIKKGLVKQEDVCVIDALLADIRKGFTLRKTKNRHESDAPPKTLPAEIPEENRSGKSIKDPQAGGQQMDDKAKQNNGHPSDESTLSLADALPEMGRDVGDASAPNQALPENNAGGNLPRGSRTEGPLVNLVEADGAGQGAGMASLQPGLGSGAISFSAANIGANITFVSSSSGAALREQLNGSTSEEQDKKCPGDGLESCRLAQDIQLNQNGGNPSTPSTPCDGAHQADLKEMAKENEDPATDSLLDTSQEKSFSEEPATDSSCSATLPPGETHTDREKQRTSGKRRKKKRHSKSYSGITARQKK", "length": 1332, "header": "tr|A0A8V0YTL1-1|A0A8V0Z7F3_CHICK Computationally mapped isoform of Inverted formin 2 OS=Gallus gallus OX=9031 GN=INF2 PE=1 SV=1 CANONICAL=A0A8V0Z7F3-1" }, "locus": { "chromosome": "5", "start_pos": 51026660, "end_pos": 50991867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041675.1", "url": "https://www.ensembl.org/id/ENSGALT00010041675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024377.1", "url": "https://www.ensembl.org/id/ENSGALP00010024377.1" } ] } }, { "isoform_ac": "A0A8V0Z7D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3/entry#A0A8V0Z7D5-1", "sequence": { "sequence": "MSIKKEGAHKKWAALKEKLGPQDTDQSEANLENAEPELCIRLLQMPSVVNYSGLKKRLENSDDAWMVQFLELCGLDLLLEALDRLSGRGVARISDALLQLTCINCVRAVMNSHRGIEYIVSNEGYVRKLFQALDTTNVMVKKQVFELLAALCIYSSDGHGLALDALDHYKNVKNQQYRFSVIMNELSNTDNVPYMVTLLSAINAIILGKEDLRTRTQIRNEFIGLQLLDILDKLRDIEEEDLLIQCDTFEEFKIEDDEELLKICDGINMNDHHEVFSSLFNKVSRSPISIQLLSILQSLLYLEPSHHSSLLLWESLDAVVNRALLLANDIQGNTVEEVIERLLSIKKHPNKQKRAEKRLSGNANGGIQTEREPCTSAVQSLMGSPNPCKTPEAPSGPQACEEKTSSSQLSACFTSPQTSNPPPNAAPALPPPPPPPPPPPPPPLPSGPAAMPPTASVNFPPAPPLPGIPPPPPPLPGMAVIPPPPPLPGMAVIPPPPPPLPGMGGIPPPPPLPGMGGIPPPPPLPGLGGIPPPPPLPGLAGIPPPPPLPGMGGIPPPPPLSGMGGIPPPPPPLPGMAGDNIEAVVAPQFSCPLGFISPPRKAVKTPTMRMKKLNWQKLPSNVVRESHSMWASVSSSSEETIEPNYTSIEQLFCFPQPTPKEKTAAPVKAEPKEITFLDSKKSLNLNIFLKQFKCSNEEVAAMVQNGDRTKFDVEVLKQLLKLLPEKHEIENLKAFKEEKSKLANADQFYLLLLQIPSYQLRIECMLICEETTVVLDMIQPKAEAIRKACEDLLTSHRLPLFCKLILKVGNFLNYGSHTGDADGFKISTLLKLTETKANQTRITLLHHILEEVENSHTDLLELPEDLEYVSKAAGINLDIIRSESSANLKKLLELQRKVSSANDDVKQQYEKPIQDSIDASRKLEEDFETIDRKREELANYLCEDPTKLSLEDVFSTMKTFRDLFIRALKENKDRKEQAAKAEKRKKQLEEEEGKRQKGENGKVIKKGLVKQEDVCVIDALLADIRKGFTLRKTKNRHESDAPPKTLPAEIPEENRSGKSIKDPQAGGQQMDDKAKQNNGHPSDESTLSLADALPEMGRDVGDASAPNQALPENNAGGNLPRGSRTEGPLVNLVEADGAGQGAGMASLQPGLGSGAISFSAANIGANITFVSSSSGAALREQLNGSTSEEQDKKCPGDGLESCRLAQDIQLNQNGGNPSTPSTPCDGAHQADLKEMAKENEDPATDSLLDTSQEKSFSEEPATDSSCSATLPPGETHTDREKQRTSGKRRKKKRHSKSYSGITARQKK", "length": 1307, "header": "tr|A0A8V0Z7D5-1|A0A8V0Z7D5_CHICK Computationally mapped isoform of Inverted formin 2 OS=Gallus gallus OX=9031 GN=INF2 PE=1 SV=1 CANONICAL=A0A8V0Z7F3-1" }, "locus": { "chromosome": "5", "start_pos": 51026660, "end_pos": 51005857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041659.1", "url": "https://www.ensembl.org/id/ENSGALT00010041659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024368.1", "url": "https://www.ensembl.org/id/ENSGALP00010024368.1" } ] } }, { "isoform_ac": "A0A8V0Z7E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3/entry#A0A8V0Z7E1-1", "sequence": { "sequence": "MSIKKEGAHKKWAALKEKLGPQDTDQSEANLENAEPELCIRLLQMPSVVNYSGLKKRLENSDDAWMVQFLELCGLDLLLEALDRLSGRGVARISDALLQLTCINCVRAVMNSHRGIEYIVSNEGYVRKLFQALDTTNVMVKKQVFELLAALCIYSSDGHGLALDALDHYKNVKNQQYRFSVIMNELSNTDNVPYMVTLLSAINAIILGKEDLRTRTQIRNEFIGLQLLDILDKLRDIEEEDLLIQCDTFEEFKIEDDEELLKICDGINMNDHHEVFSSLFNKVSRSPISIQLLSILQSLLYLEPSHHSSLLLWESLDAVVNRALLLANDIQGNTVEEVIERLLSIKKHPNKQKRAEKRLSGNANGGIQTEREPCTSAVQSLMGSPNPCKTPEAPSGPQACEEKTSSSQLSACFTSPQTSNPPPNAAPALPPPPPPPPPPPPPPLPSGPAAMPPTASVNFPPAPPLPGIPPPPPPLPGMAVIPPPPPLPGMAVIPPPPPPLPGMGGIPPPPPLPGMGGIPPPPPLPGLGGIPPPPPLPGLAGIPPPPPLPGMGGIPPPPPLSGMGGIPPPPPPLPGMAGDNIEAVVAPQFSCPLGFISPPRKAVKTPTMRMKKLNWQKLPSNVVRESHSMWASVSSSSEETIEPNYTSIEQLFCFPQPTPKEKTAAPVKAEPKEITFLDSKKSLNLNIFLKQFKCSNEEVAAMVQNGDRTKFDVEVLKQLLKLLPEKHEIENLKAFKEEKSKLANADQFYLLLLQIPSYQLRIECMLICEETTVVLDMIQPKAEAIRKACEDLLTSHRLPLFCKLILKVGNFLNYGSHTGDADGFKISTLLKLTETKANQTRITLLHHILEEVENSHTDLLELPEDLEYVSKAAGINLDIIRSESSANLKKLLELQRKVSSANDDVKQQYEKPIQDSIDASRKLEEDFETIDRKREELANYLCEDPTKLSLEDVFSTMKTFRDLFIRALKENKDRKEQAAKAEKRKKQLEEEEGKRQKGENGKVIKKGLVKQEDVCVIDALLADIRKGFTLRKTKNRHESDAPPKTLPAEIPEENRSGKSIKDPQAGGQQMDDKAKQNNGHPSDESTLSLADALPEMGRDVGDASAPNQALPENNAGGNLPRGSRTEGPLVNLVEADGAGQGAGMASLQPGLGSGAISFSAANIGANITFVSSSSGAALREQLNGSTSEEQDKKCPGDGLESCRLAQDIQLNQNGGNPSTPSTPCDGAHQADLKEMAKENEDPATDSLLDTSQEKSFSEEPATDSSCSATLPPGETHTDREKQRTSGKRRKKKRHSKSYSAEVETDSGDYKTKKGCVVQ", "length": 1318, "header": "tr|A0A8V0Z7E1-1|A0A8V0Z7E1_CHICK Computationally mapped isoform of Inverted formin 2 OS=Gallus gallus OX=9031 GN=INF2 PE=1 SV=1 CANONICAL=A0A8V0Z7F3-1" }, "locus": { "chromosome": "5", "start_pos": 51022990, "end_pos": 51005857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041668.1", "url": "https://www.ensembl.org/id/ENSGALT00010041668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024373.1", "url": "https://www.ensembl.org/id/ENSGALP00010024373.1" } ] } }, { "isoform_ac": "A0A8V0Z7F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3/entry#A0A8V0Z7F3-1", "sequence": { "sequence": "MILRLIAHRCDSFLPALLGRDKQFTMSIKKEGAHKKWAALKEKLGPQDTDQSEANLENAEPELCIRLLQMPSVVNYSGLKKRLENSDDAWMVQFLELCGLDLLLEALDRLSGRGVARISDALLQLTCINCVRAVMNSHRGIEYIVSNEGYVRKLFQALDTTNVMVKKQVFELLAALCIYSSDGHGLALDALDHYKNVKNQQYRFSVIMNELSNTDNVPYMVTLLSAINAIILGKEDLRTRTQIRNEFIGLQLLDILDKLRDIEEEDLLIQCDTFEEFKIEDDEELLKICDGINMNDHHEVFSSLFNKVSRSPISIQLLSILQSLLYLEPSHHSSLLLWESLDAVVNRALLLANDIQGNTVEEVIERLLSIKKHPNKQKRAEKRLSGNANGGIQTEREPCTSAVQSLMGSPNPCKTPEAPSGPQACEEKTSSSQLSACFTSPQTSNPPPNAAPALPPPPPPPPPPPPPPLPSGPAAMPPTASVNFPPAPPLPGIPPPPPPLPGMAVIPPPPPLPGMAVIPPPPPPLPGMGGIPPPPPLPGMGGIPPPPPLPGLGGIPPPPPLPGLAGIPPPPPLPGMGGIPPPPPLSGMGGIPPPPPPLPGMAGDNIEAVVAPQFSCPLGFISPPRKAVKTPTMRMKKLNWQKLPSNVVRESHSMWASVSSSSEETIEPNYTSIEQLFCFPQPTPKEKTAAPVKAEPKEITFLDSKKSLNLNIFLKQFKCSNEEVAAMVQNGDRTKFDVEVLKQLLKLLPEKHEIENLKAFKEEKSKLANADQFYLLLLQIPSYQLRIECMLICEETTVVLDMIQPKAEAIRKACEDLLTSHRLPLFCKLILKVGNFLNYGSHTGDADGFKISTLLKLTETKANQTRITLLHHILEEVENSHTDLLELPEDLEYVSKAAGINLDIIRSESSANLKKLLELQRKVSSANDDVKQQYEKPIQDSIDASRKLEEDFETIDRKREELANYLCEDPTKLSLEDVFSTMKTFRDLFIRALKENKDRKEQAAKAEKRKKQLEEEEGKRQKGENGKVIKKGLVKQEDVCVIDALLADIRKGFTLRKTKNRHESDAPPKTLPAEIPEENRSGKSIKDPQAGGQQMDDKAKQNNGHPSDESTLSLADALPEMGRDVGDASAPNQALPENNAGGNLPRGSRTEGPLVNLVEADGAGQGAGMASLQPGLGSGAISFSAANIGANITFVSSSSGAALREQLNGSTSEEQDKKCPGDGLESCRLAQDIQLNQNGGNPSTPSTPCDGAHQADLKEMAKENEDPATDSLLDTSQEKSFSEEPATDSSCSATLPPGETHTDREKQRTSGKRRKKKRHSKSYSEVETDSGDYKTKKGCVVQ", "length": 1342, "header": "tr|A0A8V0Z7F3-1|A0A8V0Z7F3_CHICK Isoform 1 of Inverted formin 2 OS=Gallus gallus OX=9031 GN=INF2 PE=1 SV=1 CANONICAL=A0A8V0Z7F3-1" }, "locus": { "chromosome": "5", "start_pos": 51022990, "end_pos": 50991867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041682.1", "url": "https://www.ensembl.org/id/ENSGALT00010041682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024383.1", "url": "https://www.ensembl.org/id/ENSGALP00010024383.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1244, "start_aa": "Thr", "end_pos": 1244, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1244", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LVR6-1", "protein_name": "Inverted formin-2", "gene_name": "Inf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSWRQGPEWVGRGSRKVLRIWFNKMSVKEGAQRKWAALKEKLGPQDSDPTEANLESAEPELCIRLLQMPSVVNYSGLRKRLESSDGSWMVQFLEQSGLDLLLEALARLSGRGVARIADALLQLTCISCVRAVMNSQQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQYRFSVIMNELSDSDNVPYVVTLLSVINALILGPEDLRTRAQLRSEFIGLQLLDILTRLRDLEDADLLIQLEAFEEAKAEDEEELQRVSDGINMNSHQEVFTSLFHKVSCSPASAQLLSVLQGLMHLEPAARSGQLLWEALENLVNRAVLLASDAEACTLEEVVERLLSIKGRPRPSPLDKAHKSVQTNLGQNQGSSSQNTATPTAKVEGRQPVVASPCQHVGSIQSSSMDAAPQLAASPLPTPPLSSSTPVLPPPPPPLPGSGATSPPAPPPPPPLPPPLPGSGTMSPPPPPPPPLPPPLPGLGAVSPPPPPPPPPLPGSRAVSPPAPPPSLPHSHPLPPPPPPPPLPGMCPVPPPPPLPTAGQVPPPPPLPGFSVPSVVGGVEEIIVAQVDHSLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLSSPCTAEVEPDFSSIEQLFSFPMAKPKEPSAAPARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEVTGMIQAGDTSKFDVEVLKQLLKLLPEKHEIENLRAFTEDRAKLASADQFYILLLDIPCYQLRVECMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKISTLLKLTETKSQQSRVTLLHHVLEEVEKSHPDLLQLSRDLESPSQAAGIHLEIIHSEASANLKKLLEAERKVSSSIPEVQKQYAERLQASIEASRALDKVFDAIEQKKLELADYLCEDPQKLSLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAEKRKQQLAEEEARRPRDEDGKPVRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTEASGRVAPADPPKITEPATASNPTQGTNQPASEPSSDTTAAGEPQGWDLVDAVTPSPQPTKEDGGPPSLERRSSWYVDASDFLAPEDILNTQPSEGAWPVTLGDDQALKPLEFSSNKPPGVERSHQDATDPEALWGVHRAEADSTSVRPEDATERGQGTHLPRPGEDEDEEDTALESALDTSLDRSFSEDAVTDSSGSGTLPRVQGRISKGTGKRRKKRPSRRQEEFAPDSDDNKAKRLCVIQ", "length": 1286 }, "evidence": [ { "id": "A0A8V0Z7F3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7F3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0GNC1-1", "protein_name": "Inverted formin-2", "gene_name": "Inf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVKEGAQRKWAALKEKLGPQDSDPTEANLESAEPELCIRLLQMPSVVNYSGLRKRLESSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCISCVRAVMNSQQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQYRFSVIMSELSDSDNVPYVVTLLSVINAIILGPEDLRSRAQLRSEFIGLQLLDILTRLRDLEDADLLIQLEAFEEAKAEDEEELQRISDGINMNSHQEVFASLFHKVSCSPASAQLLSVLQGLMHLEPAGRSGQLLWEALENLVNRAVLLASDAQACTLEEVVERLLSIKGRPRPSPLDKAHKSVQTNSVQNQGSSSQNTTTPTTKVEGQQPVVASPCQHVGSIQSSSVDIAPQPVALEQCITALPLPTPPLSSSTPVLPPTPPPLPGPGATSPLPPPPPPLPPPLPGSGTTSPPPPPPPPPPLPPPLPGSGTISPPPPPPPPPLPGTGAVSPPPPPPLPSLPDSHKTQPPPPPPPPLPGMCPVPPPPPLPRAGQIPPPPPLPGFSVPSMMGGVEEIIVAQVDHSLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLGSPCTAAVEPDFSSIEQLFSFPTAKPKEPSAAPARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEVTSMIQAGDTSKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLSNADQFYVLLLDIPCYPLRVECMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKISTLLKLTETKSQQSRVTLLHHVLEEVEKSHPDLLQLSRDLEPPSQAAGINVEIIHSEASANLKKLLEAERKVSASIPEVQKQYAERLQASIEASQELDKVFDAIEQKKLELADYLCEDPQQLSLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAERRKQQLAEEEARRPRDEDGKPIRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTEASGRVAPTDPPKATEPATASNPTQGTNHPASEPLDTTAADEPQGWDLVDAVTPSPQPSKEEDGPPALERRSSWYVDAIDFLDPEDTPDAQPSEGVWPVTLGDGQALNPLEFSSNKPPGVKSSHQDATDPEALWGVHQTEADSTSEGPEDEAQRGQSTHLPRTGPGEDEDGEDTAPESALDTSLDRSFSEDAVTDSSGSGTLPRVQGRVSKGTSKRRKKRPSRNQEEFVPDSDDIKAKRLCVIQ", "length": 1273 }, "evidence": [ { "id": "A0A8V0Z7F3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7F3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q27J81-1", "protein_name": "Inverted formin-2", "gene_name": "INF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLRDLEDADLLIQLEAFEEAKAEDEEELLRVSGGVDMSSHQEVFASLFHKVSCSPVSAQLLSVLQGLLHLEPTLRSSQLLWEALESLVNRAVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVAREHNSMWASLSSPDAEAVEPDFSSIERLFSFPAAKPKEPTMVAPRARKEPKEITFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAACESLLTSRQLPIFCQLILRIGNFLNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLLQLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKVSASVAEVQEQYTERLQASISAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDTFSTMKAFRDLFLRALKENKDRKEQAAKAERRKQQLAEEEARRPRGEDGKPVRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTDGGSKAASMDPPRATEPVATSNPAGDPVGSTRCPASEPGLDATTASESRGWDLVDAVTPGPQPTLEQLEEGGPRPLERRSSWYVDASDVLTTEDPQCPQPLEGAWPVTLGDAQALKPLKFSSNQPPAAGSSRQDAKDPTSLLGVLQAEADSTSEGLEDAVHSRGARPPAAGPGGDEDEDEEDTAPESALDTSLDKSFSEDAVTDSSGSGTLPRARGRASKGTGKRRKKRPSRSQEEVPPDSDDNKTKKLCVIQ", "length": 1249 }, "evidence": [ { "id": "A0A8V0Z7F3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7F3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1191, "end_pos": 1193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 625, "end_pos": 1015, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z7F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" }, { "id": "PS51232", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GBD/FH3", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 356, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z7F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F3" }, { "id": "PS51082", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH2", "eco_id": "ECO_0000259", "start_pos": 1043, "end_pos": 1058, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1244 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1079, "end_pos": 1081 }, { "start_pos": 1191, "end_pos": 1193 }, { "start_pos": 1208, "end_pos": 1210 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 863, "end_pos": 865 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5E2-1", "uniprot_ac": "A0A8V0Z5E2", "uniprot_id": "A0A8V0Z5E2_CHICK", "mass": { "chemical_mass": 68109.0, "monoisotopic_mass": 68109.0 }, "refseq": { "ac": "XP_040528887", "name": "spermatogenesis-associated protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528887" }, "gene_names": [ { "name": "SPATA7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ] }, { "name": "SPATA7", "type": "synonym", "evidence": [ { "id": "XP_040528887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528887" } ] } ], "protein_names": [ { "name": "Spermatosis associated 7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040528887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528887" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040528887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528887" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2", "locus": { "chromosome": "5", "start_pos": 42596486, "end_pos": 42561736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017921", "url": "https://www.ensembl.org/id/ENSGALG00010017921" } ] } } ], "crossref": [ { "id": "A0A8V0Z5E2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5E2", "database": "AlphaFoldDB", "categories": [] }, { "id": "423397", "url": "https://www.ncbi.nlm.nih.gov/gene/423397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423397", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FITEHEW", "url": "https://omabrowser.org/oma/group/FITEHEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXF7", "url": "https://www.orthodb.org/?gene=A0A8V0YXF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4A3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5E2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB84", "url": "https://www.orthodb.org/?gene=A0A8V0ZB84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14917:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14917:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040528887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAEAAGPGHVAPSQTQRPAPPGRCGDRAAAALNRELGSPESMGVTMESDGRRSQVNEYPAVVIPRCGPASPFKGQLSTKSNAFCIDSSRSLTKQYLIRDHLMFHYNRILSAKAAVDCSVPRSSLSSIKLADQQRRENLKKKIARYEKEMSVGKSASRSSSRESGRLLSTSFGKSPLEVEDKDNLFSCAEHTPYLSRALSPYGELGLLHSSPVKRARKHSRNRSNASYSNSSVSMSSTPRKRSGVSSRCSSDSFVSISHSQRRQERSSTTYSGDLLDRHAELFTNSQKPFTPRTLISDAKSALLGYRYYTAAQRQRKKHCKQNVEVETQTDVISVPNTDKASERKVMTEQRKMTVKTEDKIYNMDEPERGIAAFPYSFLREASLYAEQPSARMNIEAVEEDDHLYLTFIEDVTNEILNIGLFSNRVLEQLFECHIEEYKNRLDESKMRHLLDVLKADLGCSPGSGAEQIRAGWEAFELLDLGKFNMMEQLEFSSRSRRQGKATRSEEFFKTLDLLLKEPSTCEVPLCSENSKKTESKGDFSEDIDEMMNAETESHVCVKSEDPDASPSCEETLNLITCDSDLEANKELDDLEENFAEVLQIAHDHSL", "length": 608, "header": "tr|A0A8V0Z5E2-1|A0A8V0Z5E2_CHICK Isoform 1 of Spermatosis associated 7 OS=Gallus gallus OX=9031 GN=SPATA7 PE=4 SV=1 CANONICAL=A0A8V0Z5E2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2/entry#A0A8V0YXF7-1", "sequence": { "sequence": "MATAEAAGPGHVAPSQTQRPAPPGRCGDRAAAALNRELGSPESMGVTMESDGRRSQVNEYPAVVIPRCGPASPFKGQLSTKSNAFCIDSSRSLTKQYLIRDHLMFHYNRILSAKAAVDCSVPRSSLSSIKLADQQRRENLKKKIARYEKEMSVGKSASRSSSRESGRLLSTSFGKSPLEVEDKDNLFSCAEHTPYLSRALSPYGELGLLHSSPVKRARKHSRNRSNASYSNSSVSMSSTPRKRSGVSSRCSSDSFVSISHSQRRQERSSTTYSGDLLDRYYTAAQRQRKKHCKQNVEVETQTDVISVPNTDKASERKVMTEQRKMTVKTEDKIYNMDEPERGIAAFPYSFLREASLYAEQPSARMNIEAVEEDDHLYLTFIEDVTNEILNIGLFSNRVLEQLFECHIEEYKNRLDESKMRHLLDVLKADLGCSPGSGAEQIRAGWEAFELLDLGKFNMMEQLEFSSRSRRQGKATRSEEFFKTLDLLLKEPSTCEVPLCSENSKKTESKGDFSEDIDEMMNAETESHVCVKSEDPDASPSCEETLNLITCDSDLEANKELDDLEENFAEVLQIAHDHSL", "length": 579, "header": "tr|A0A8V0YXF7-1|A0A8V0Z5E2_CHICK Computationally mapped isoform of Spermatosis associated 7 OS=Gallus gallus OX=9031 GN=SPATA7 PE=4 SV=1 CANONICAL=A0A8V0Z5E2-1" }, "locus": { "chromosome": "5", "start_pos": 42596135, "end_pos": 42561972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043336.1", "url": "https://www.ensembl.org/id/ENSGALT00010043336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025759.1", "url": "https://www.ensembl.org/id/ENSGALP00010025759.1" } ] } }, { "isoform_ac": "A0A8V0Z4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2/entry#A0A8V0Z4A3-1", "sequence": { "sequence": "MGRESGLVVSMNLCALGDQRFFFSKAVNEYPAVVIPRCGPASPFKGQLSTKSNAFCIDSSRSLTKQYLIRDHLMFHYNRILSAKAAVDCSVPRSSLSSIKLADQQRRENLKKKIARYEKEMSVGKSASRSSSRESGRLLSTSFGKSPLEVEDKDNLFSCAEHTPYLSRALSPYGELGLLHSSPVKRARKHSRNRSNASYSNSSVSMSSTPRKRSGVSSRCSSDSFVSISHSQRRQERSSTTYSGDLLDRHAELFTNSQKPFTPRTLISDAKSALLGYRYYTAAQRQRKKHCKQNVEVETQTDVISVPNTDKASERKVMTEQRKMTVKTEDKIYNMDEPERGIAAFPYSFLREASLYAEQPSARMNIEAVEEDDHLYLTFIEDVTNEILNIGLFSNRVLEQLFECHIEEYKNRLDESKMRHLLDVLKADLGCSPGSGAEQIRAGWEAFELLDLGKFNMMEQLEFSSRSRRQGKATRSEEFFKTLDLLLKEPSTCEVPLCSENSKKTESKGDFSEDIDEMMNAETESHVCVKSEDPDASPSCEETLNLITCDSDLEANKELDDLEENFAEVLQIAHDHSL", "length": 578, "header": "tr|A0A8V0Z4A3-1|A0A8V0Z4A3_CHICK Computationally mapped isoform of Spermatosis associated 7 OS=Gallus gallus OX=9031 GN=SPATA7 PE=4 SV=1 CANONICAL=A0A8V0Z5E2-1" }, "locus": { "chromosome": "5", "start_pos": 42596135, "end_pos": 42562580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043329.1", "url": "https://www.ensembl.org/id/ENSGALT00010043329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025753.1", "url": "https://www.ensembl.org/id/ENSGALP00010025753.1" } ] } }, { "isoform_ac": "A0A8V0Z5E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2/entry#A0A8V0Z5E2-1", "sequence": { "sequence": "MATAEAAGPGHVAPSQTQRPAPPGRCGDRAAAALNRELGSPESMGVTMESDGRRSQVNEYPAVVIPRCGPASPFKGQLSTKSNAFCIDSSRSLTKQYLIRDHLMFHYNRILSAKAAVDCSVPRSSLSSIKLADQQRRENLKKKIARYEKEMSVGKSASRSSSRESGRLLSTSFGKSPLEVEDKDNLFSCAEHTPYLSRALSPYGELGLLHSSPVKRARKHSRNRSNASYSNSSVSMSSTPRKRSGVSSRCSSDSFVSISHSQRRQERSSTTYSGDLLDRHAELFTNSQKPFTPRTLISDAKSALLGYRYYTAAQRQRKKHCKQNVEVETQTDVISVPNTDKASERKVMTEQRKMTVKTEDKIYNMDEPERGIAAFPYSFLREASLYAEQPSARMNIEAVEEDDHLYLTFIEDVTNEILNIGLFSNRVLEQLFECHIEEYKNRLDESKMRHLLDVLKADLGCSPGSGAEQIRAGWEAFELLDLGKFNMMEQLEFSSRSRRQGKATRSEEFFKTLDLLLKEPSTCEVPLCSENSKKTESKGDFSEDIDEMMNAETESHVCVKSEDPDASPSCEETLNLITCDSDLEANKELDDLEENFAEVLQIAHDHSL", "length": 608, "header": "tr|A0A8V0Z5E2-1|A0A8V0Z5E2_CHICK Isoform 1 of Spermatosis associated 7 OS=Gallus gallus OX=9031 GN=SPATA7 PE=4 SV=1 CANONICAL=A0A8V0Z5E2-1" }, "locus": { "chromosome": "5", "start_pos": 42596135, "end_pos": 42561972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043334.1", "url": "https://www.ensembl.org/id/ENSGALT00010043334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025757.1", "url": "https://www.ensembl.org/id/ENSGALP00010025757.1" } ] } }, { "isoform_ac": "A0A8V0ZB84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2/entry#A0A8V0ZB84-1", "sequence": { "sequence": "MSCALQLWELSMLIQTQQGPKKILVNEYPAVVIPRCGPASPFKGQLSTKSNAFCIDSSRSLTKQYLIRDHLMFHYNRILSAKAAVDCSVPRSSLSSIKLADQQRRENLKKKIARYEKEMSVGKSASRSSSRESGRLLSTSFGKSPLEVEDKDNLFSCAEHTPYLSRALSPYGELGLLHSSPVKRARKHSRNRSNASYSNSSVSMSSTPRKRSGVSSRCSSDSFVSISHSQRRQERSSTTYSGDLLDRHAELFTNSQKPFTPRTLISDAKSALLGYRYYTAAQRQRKKHCKQNVEVETQTDVISVPNTDKASERKVMTEQRKMTVKTEDKIYNMDEPERGIAAFPYSFLREASLYAEQPSARMNIEAVEEDDHLYLTFIEDVTNEILNIGLFSNRVLEQLFECHIEEYKNRLDESKMRHLLDVLKADLGCSPGSGAEQIRAGWEAFELLDLGKFNMMEQLEFSSRSRRQGKATRSEEFFKTLDLLLKEPSTCEVPLCSENSKKTESKGDFSEDIDEMMNAETESHVCVKSEDPDASPSCEETLNLITCDSDLEANKELDDLEENFAEVLQIAHDHSL", "length": 576, "header": "tr|A0A8V0ZB84-1|A0A8V0ZB84_CHICK Computationally mapped isoform of Spermatosis associated 7 OS=Gallus gallus OX=9031 GN=SPATA7 PE=4 SV=1 CANONICAL=A0A8V0Z5E2-1" }, "locus": { "chromosome": "5", "start_pos": 42596135, "end_pos": 42569550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043325.1", "url": "https://www.ensembl.org/id/ENSGALT00010043325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025750.1", "url": "https://www.ensembl.org/id/ENSGALP00010025750.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 311, "start_aa": "Thr", "end_pos": 311, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr311", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423397", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423397", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QGP2-1", "protein_name": "Spermatosis associated 7", "gene_name": "SPATA7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "NAGSKLLLATSVLPRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLHLVKNHMAVHYNKILSAKAAVDCSVPLSMSASIKYADQQRREKLKKELARCERELKFTKTAGQANSKSNSKSLFTTLQKPSGEPQDEDDVLIEEVNGFPSFTRSPVTSSERLHPGLPKSEKVLTNGTENNSSSPLSSMDYAASGPRKSYSGTSCSRRPRGAFPNSHRFQLVISKAPSGDLLDKHSELFSNRHLPFTPRTLKSEAKSFLSQYRYYTPAKRKKDFTNQRIEAETQTDLSSFKSDFETNEIKNFTDSEMNIKQGRELPWDETKDGALQCSSARAVCQYSLHPPSERKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEEKMRHLLHILKVDLGCISKENSVKLDDVSMLHLPDFEKAEDSDQNEYKNEQDLAIRQERQQYRKALDMLLSVPKDENEVVSSPNEFFLPIYKSKYSEGVIIQQVNDETNLGTSIWDEKNAGMLDSVLDQETSVNVIEGDSDTEKVETSNELCCLSTALSPSVQLCSISGDNQNTEGPTLKIMEMSIED", "length": 576 }, "evidence": [ { "id": "A0A8V0Z5E2", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80VP2-1", "protein_name": "Spermatogenesis-associated protein 7 homolog", "gene_name": "Spata7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGSRRVRATSVLPRYSPPCLFTGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAIHYNKILSAKAAVDCSIPVSVNTSIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQKPSGEPQDQDVFIEEMTRYPSFSKSLIPSSEGLHLSLPESSKMLMSGTQKHASTSPSRHSGCGHGCDRRPRSAHQFQVALAKTPSGDLLEKHSDLFSNKQSPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFSDQRMEAETQTELSSFNSELGTAEKTSSKDSEVNINQVPNYTRNGAEDKIAPLPSQGQNLAWDSIQDGILQQSSERASCKLSTEFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIKKNKHHLEEGKMRYLLHGLKVDLGCISEEDPAKQKHFRMLNQLHFQKALISRENEFVSDEETVSHHERQQYQEALDMLSAVPKDENKMFSLPGEFLIPAHKVKHSEGVIIQQVNDETDNEASPWNENNPSVSDSVIDQETSVDVIEGDSDFERAETSRELCCLSTSLSPSGPFPSINGGSNHGKELSTLRIMGMSIED", "length": 582 }, "evidence": [ { "id": "A0A8V0Z5E2", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P0W8-1", "protein_name": "Spermatogenesis-associated protein 7", "gene_name": "SPATA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGSRRVRATSVLPRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAVHYNKILSAKAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELSFKSELGTAETKNMTDSEMNIKQASNCVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNKHLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTLKIMEMSIEDCPLDV", "length": 599 }, "evidence": [ { "id": "A0A8V0Z5E2", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0A3-1", "protein_name": "Spermatogenesis-associated protein 7 homolog", "gene_name": "Spata7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVHYNKILSAKAAVDCSIPVSVNASIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQRPSGEPQDQDVLIEERLTRYPSFSKSLIPSPEGLHLSLPESNKILMNGTQKYPSTAPPRYSGCGHGYDRRPRSAHQFQVVISKTPSGDLLEKHADLFSNNQSPFTPRTLKTEAKSFLSQYRYYTPAKRRRDFSDQRMEAETQTELSSFNSELGTAEKKSSKDSDVSIKQAPNYMRNGAEDKIAPLSLQGQNLAWDKSKDGILQPSSERAPCTQFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIRKNKHHLEEGKMRYLLHGLKVDLGCISEEEQNSFRIFNEFHFQKALTSRENRFINDTEAVNHHERQQYQEALNMLSSVPKDENKMFSFPGEFLLPAHKVKHSEGVIVQQVNDETDFEALPWDGNNPSVSDSFIDQETSVDVIEGDSDFEMVETSRELCCLSTSLSPSVPLPSIEGGSNHDKELSTLKIMEMSIED", "length": 526 }, "evidence": [ { "id": "A0A8V0Z5E2", "url": "https://omabrowser.org/oma/group/A0A8V0Z5E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to photoreceptor connecting cilium", "id": "GO:1903621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903621", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "protein localization to photoreceptor outer segment", "id": "GO:1903546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "photoreceptor distal connecting cilium", "id": "GO:0120206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120206", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" }, { "name": "rod photoreceptor outer segment", "id": "GO:0120200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 311 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 231, "end_pos": 233 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5K4-1", "uniprot_ac": "A0A8V0Z5K4", "uniprot_id": "A0A8V0Z5K4_CHICK", "mass": { "chemical_mass": 57584.0, "monoisotopic_mass": 57584.0 }, "refseq": {}, "gene_names": [ { "name": "LOC422147", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" } ] } ], "protein_names": [ { "name": "Putative P2Y purinoceptor 10", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative receptor for purines coupled to G-proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4#function" }, { "database": "UniProtKB", "id": "ARBA00056731", "url": "https://www.uniprot.org/uniprotkb/ARBA00056731#function" }, { "database": "UniProtKB", "id": "A0A8V0YXM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422147", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15153", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15153", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422147", "url": "https://www.ncbi.nlm.nih.gov/gene/422147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422147", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPQMSFQ", "url": "https://omabrowser.org/oma/group/DPQMSFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXM9", "url": "https://www.orthodb.org/?gene=A0A8V0YXM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5K4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-417957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-417957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YXM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLWSRKKSSAKLRPAALVAVTPPPFQLFSRHSPNTFCVLEGNEIQDFLFCSRCAGLQMPAGFLPALQNHVGVWRGAAGAGSAARSRRKAKPRARCSCSLAWMPAPCRMGAAGSVIIHHLCLLLAGSLRPPEPTGERRVWVAMESNVSSGNCSQPQMSFQSTLYAATYTIIFIPGLLANSAALWVLCRFISKKSKAVIFMINLAVADLAHVLSLPLRMYYYINHTWPFGTFLCQLCFYLKYLNMYASICFLTCISIQRYLFLLHPFKATAWKRRYDVGLSAAVWLFVGAACLPLPIVRSPALSNSTTTCFSDLAVKQLTPGASIALVTVAELFGFVIPFGIIAWCTWKMRQSLQEGGTQLQSTSEKQKALRMVLMCAAVFFICFTPYHINFPFFMMVIENIIKDCTVHSNTLRFHPISLCLASLNCCLDPVLYYFMTSEFQDQLLRHGCAALWARLARSRRSLTMSNVGHNIRTKRRNLPRFQFWSLPKFFGRINSMEIPPMQPDELLLESIS", "length": 513, "header": "tr|A0A8V0Z5K4-1|A0A8V0Z5K4_CHICK Isoform 1 of Putative P2Y purinoceptor 10 OS=Gallus gallus OX=9031 GN=LOC422147 PE=4 SV=1 CANONICAL=A0A8V0Z5K4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4/entry#A0A8V0YXM9-1", "sequence": { "sequence": "MESNVSSGNCSQPQMSFQSTLYAATYTIIFIPGLLANSAALWVLCRFISKKSKAVIFMINLAVADLAHVLSLPLRMYYYINHTWPFGTFLCQLCFYLKYLNMYASICFLTCISIQRYLFLLHPFKATAWKRRYDVGLSAAVWLFVGAACLPLPIVRSPALSNSTTTCFSDLAVKQLTPGASIALVTVAELFGFVIPFGIIAWCTWKMRQSLQEGGTQLQSTSEKQKALRMVLMCAAVFFICFTPYHINFPFFMMVIENIIKDCTVHSNTLRFHPISLCLASLNCCLDPVLYYFMTSEFQDQLLRHGCAALWARLARSRRSLTMSNVGHNIRTKRRNLPRFQFWSLPKFFGRINSMEIPPMQPDELLLESIS", "length": 371, "header": "tr|A0A8V0YXM9-1|A0A8V0Z5K4_CHICK Computationally mapped isoform of Putative P2Y purinoceptor 10 OS=Gallus gallus OX=9031 GN=LOC422147 PE=4 SV=1 CANONICAL=A0A8V0Z5K4-1" }, "locus": { "chromosome": "4", "start_pos": 1405228, "end_pos": 1404116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043436.1", "url": "https://www.ensembl.org/id/ENSGALT00010043436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025819.1", "url": "https://www.ensembl.org/id/ENSGALP00010025819.1" } ] } }, { "isoform_ac": "A0A8V0Z5K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4/entry#A0A8V0Z5K4-1", "sequence": { "sequence": "MQLWSRKKSSAKLRPAALVAVTPPPFQLFSRHSPNTFCVLEGNEIQDFLFCSRCAGLQMPAGFLPALQNHVGVWRGAAGAGSAARSRRKAKPRARCSCSLAWMPAPCRMGAAGSVIIHHLCLLLAGSLRPPEPTGERRVWVAMESNVSSGNCSQPQMSFQSTLYAATYTIIFIPGLLANSAALWVLCRFISKKSKAVIFMINLAVADLAHVLSLPLRMYYYINHTWPFGTFLCQLCFYLKYLNMYASICFLTCISIQRYLFLLHPFKATAWKRRYDVGLSAAVWLFVGAACLPLPIVRSPALSNSTTTCFSDLAVKQLTPGASIALVTVAELFGFVIPFGIIAWCTWKMRQSLQEGGTQLQSTSEKQKALRMVLMCAAVFFICFTPYHINFPFFMMVIENIIKDCTVHSNTLRFHPISLCLASLNCCLDPVLYYFMTSEFQDQLLRHGCAALWARLARSRRSLTMSNVGHNIRTKRRNLPRFQFWSLPKFFGRINSMEIPPMQPDELLLESIS", "length": 513, "header": "tr|A0A8V0Z5K4-1|A0A8V0Z5K4_CHICK Isoform 1 of Putative P2Y purinoceptor 10 OS=Gallus gallus OX=9031 GN=LOC422147 PE=4 SV=1 CANONICAL=A0A8V0Z5K4-1" }, "locus": { "chromosome": "4", "start_pos": 1405228, "end_pos": 1401357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043440.1", "url": "https://www.ensembl.org/id/ENSGALT00010043440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025822.1", "url": "https://www.ensembl.org/id/ENSGALP00010025822.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422147", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-417957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-417957", "resource": "Reactome", "description": "P2Y receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQF7-1", "protein_name": "Putative P2Y purinoceptor 10", "gene_name": "P2ry10b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSNSTSTAESNCNATNLTFQNSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYINHHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAAVWIIVGTACLPLPILRSAGLANNSESCFADLGLHDISMASSIGMVTAAELGGFVLPVVIITYCTWKTRKSLQEFQDPPQNIKERKKALRMVLMCAVVFIVCFTPYHLNFPFFMMVKQRVFSNCSFIKSTLYFHIISLCLANLNCCLDPVVYYFMTSEFRDQFSEHGNLVIQSCLRCKDSTLEIRQRKENLQTISLECLDVPTQCDEMAV", "length": 352 }, "evidence": [ { "id": "A0A8V0Z5K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HWB3-1", "protein_name": "Putative P2Y purinoceptor 10", "gene_name": "LOC100757526", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSNSTSTAENNCNVTHLTFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYINRNWPFQKALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFKARNWKRRYDVAISAAIWVIVGTACLPLPILRSAGLANNSESCFADLGLHDISMASSIGMVTAAELGGFVLPVVIITYCTWKTRKSLQEFQDPPQNIKERKKALRMVLMCAVVFIVCFTPYHLNFPFFMMVKQHVFSNCSFIKSTLCFHIISLCLANLNCCLDPVVYYFMTSEFRDQISEHGSLVIQSCVRCKDSTLEIHQRKENLQTISLECLDVPTQCDEIII", "length": 352 }, "evidence": [ { "id": "A0A8V0Z5K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5K4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 433, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 22 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V0Z5W4_CHICK", "mass": { "chemical_mass": 108464.0, "monoisotopic_mass": 108464.0 }, "refseq": {}, "gene_names": [ { "name": "GZF1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ] } ], "protein_names": [ { "name": "GDNF inducible zinc finger protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional repressor that binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YY08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY08#function" }, { "database": "UniProtKB", "id": "ARBA00053896", "url": "https://www.uniprot.org/uniprotkb/ARBA00053896#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GZF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4", "locus": { "chromosome": "3", "start_pos": 3460600, "end_pos": 3483254, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018037", "url": "https://www.ensembl.org/id/ENSGALG00010018037" } ] } } ], "crossref": [ { "id": "A0A8V0Z5W4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421233", "url": "https://www.ncbi.nlm.nih.gov/gene/421233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFMCESC", "url": "https://omabrowser.org/oma/group/PFMCESC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY08", "url": "https://www.orthodb.org/?gene=A0A8V0YY08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YY08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEKKKILMKSKVAAPNLLRALHSLYQFGHLCDVTVHTQHLGIQEEFLVHKAVLAASSNYFKGLFLHDGMLDTKNCTVTLQDIYTEEFTSFLEFVYTAEVEIEAGKLQRMKEIAERLECKDLLDICEEVRAEGKKGLDLSLHLKSQLCENGVPQWPCIQQEENRKLSSCSQVVAVPMQRKLWERQKCNKLLAGYELTEGQPANLEQEGTAFPQQKSRTIELPKCDRTDNRGRFGMDVISLEQRNTHSPVSQTVSKEACVVIRDMLSEQWEDGNSLISDLSSKTKRRRSLRRVAKVLPEIACEKCNESFHVIKQYQLHMELKHGVNLSVKYSCNMCEQLFSSHQNLRQHCLTVHSAERGFSCVFCDKKFKHQKDRNDHIQRVHEKQRDPQACPYCDKVISSKCGLTVHIRTHTGEKPYKCECCPASFAHRSAYKTHIRKIHESGQERKLMPVYWMVVPPTHRPNAASKDSDREIWDGMSEAELEKSAMHKESASCEEEPARPPVTQTDCSELQEQKQKCTEAQRGTETLSEEGNEAEGEKSVKGEEEGVHDAEYSDVEDSRDNDEACTEEDDEDDECSNEKCAEECESAEEFKIKKVNRSGVNKKSAYVIRCNKCNEQFVSRKKYVDHCRDIHQCLPGKVYQCDICSKSFASYNSWKEHRACVHTDERQFACSLCNATFKRKRDVRTHYVRKHEGRVKRPLCSVCGKILSSRTALVFHMRTHTGEKPYECGICHSKFAQPSQLKIHTRSHTGEKPYVCEDCGACFADKGKLTGHKRTHTGERLFKCDVCGKHFATNEYLKCHKRCHMGAKPYKCEVCGKTFGLRASLAQHSNVHAETRPYFCEQCGKTFTQQGALRRHQRIHTGEKPYKCRACERTFTDMSTLRRHVSIHDRNAHWRSFLIDLTTKKTHNWSKIETFSGACMGEDSVPEIWSVDRAFCREKKDGK", "length": 944, "header": "tr|A0A8V0Z5W4-1|A0A8V0Z5W4_CHICK Isoform 1 of GDNF inducible zinc finger protein 1 OS=Gallus gallus OX=9031 GN=GZF1 PE=3 SV=1 CANONICAL=A0A8V0Z5W4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4/entry#A0A8V0YY08-1", "sequence": { "sequence": "MESNAVLLESKSSPINLLNEMHQLRLLGHLCDVTVSVEYQGVRAEFVAHKAVLAATSKFFKEVFLNEKSMDGPRTNVFLNEVQVADFASFLEFVYTAKVEVEEDRVQRMLEIAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQNSEEESAAQPSSLLESKAVAVAEPEQTGCPPDPAGSPGGRPRIGLSLEVPATKPKEKADKKKEMMKPPYAKIRRASGRLAGRKVFVEIPKKKYTRRLREQQKNAEVAVEEDSYPQDQDMCGTEREEEQAEDSIKPESEECDGNFETEESVKKSEEDKKKRGSNFKCSTCEKEFLYEKSFLKHIKHSHGIAAEIVYRCETCSQTFANRCNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHILQVHEGGGERHQCQQCGKGLSSKTALRLHERTHTGDKPYGCTECEAKFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVEGASKNEEAHKTELPDEEYDVSPKMPEKLLSFSENGHYQSFTAVPGGVTALHDSSSATGTDCKSDGTLGPQGALIATTLSELTVLHTQTDSIQPQLHALVNME", "length": 707, "header": "tr|A0A8V0YY08-1|A0A8V0Z5W4_CHICK Computationally mapped isoform of GDNF inducible zinc finger protein 1 OS=Gallus gallus OX=9031 GN=GZF1 PE=3 SV=1 CANONICAL=A0A8V0Z5W4-1" }, "locus": { "chromosome": "3", "start_pos": 3467397, "end_pos": 3462264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043597.1", "url": "https://www.ensembl.org/id/ENSGALT00010043597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025930.1", "url": "https://www.ensembl.org/id/ENSGALP00010025930.1" } ] } }, { "isoform_ac": "A0A8V0Z5W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4/entry#A0A8V0Z5W4-1", "sequence": { "sequence": "MMEKKKILMKSKVAAPNLLRALHSLYQFGHLCDVTVHTQHLGIQEEFLVHKAVLAASSNYFKGLFLHDGMLDTKNCTVTLQDIYTEEFTSFLEFVYTAEVEIEAGKLQRMKEIAERLECKDLLDICEEVRAEGKKGLDLSLHLKSQLCENGVPQWPCIQQEENRKLSSCSQVVAVPMQRKLWERQKCNKLLAGYELTEGQPANLEQEGTAFPQQKSRTIELPKCDRTDNRGRFGMDVISLEQRNTHSPVSQTVSKEACVVIRDMLSEQWEDGNSLISDLSSKTKRRRSLRRVAKVLPEIACEKCNESFHVIKQYQLHMELKHGVNLSVKYSCNMCEQLFSSHQNLRQHCLTVHSAERGFSCVFCDKKFKHQKDRNDHIQRVHEKQRDPQACPYCDKVISSKCGLTVHIRTHTGEKPYKCECCPASFAHRSAYKTHIRKIHESGQERKLMPVYWMVVPPTHRPNAASKDSDREIWDGMSEAELEKSAMHKESASCEEEPARPPVTQTDCSELQEQKQKCTEAQRGTETLSEEGNEAEGEKSVKGEEEGVHDAEYSDVEDSRDNDEACTEEDDEDDECSNEKCAEECESAEEFKIKKVNRSGVNKKSAYVIRCNKCNEQFVSRKKYVDHCRDIHQCLPGKVYQCDICSKSFASYNSWKEHRACVHTDERQFACSLCNATFKRKRDVRTHYVRKHEGRVKRPLCSVCGKILSSRTALVFHMRTHTGEKPYECGICHSKFAQPSQLKIHTRSHTGEKPYVCEDCGACFADKGKLTGHKRTHTGERLFKCDVCGKHFATNEYLKCHKRCHMGAKPYKCEVCGKTFGLRASLAQHSNVHAETRPYFCEQCGKTFTQQGALRRHQRIHTGEKPYKCRACERTFTDMSTLRRHVSIHDRNAHWRSFLIDLTTKKTHNWSKIETFSGACMGEDSVPEIWSVDRAFCREKKDGK", "length": 944, "header": "tr|A0A8V0Z5W4-1|A0A8V0Z5W4_CHICK Isoform 1 of GDNF inducible zinc finger protein 1 OS=Gallus gallus OX=9031 GN=GZF1 PE=3 SV=1 CANONICAL=A0A8V0Z5W4-1" }, "locus": { "chromosome": "3", "start_pos": 3478479, "end_pos": 3467390, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043601.1", "url": "https://www.ensembl.org/id/ENSGALT00010043601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025933.1", "url": "https://www.ensembl.org/id/ENSGALP00010025933.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JTP0-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQATDPGLTTSQSPCPKSRKSTQHNARNRLCSWTCARSAFLACRGRGPSGGGAGSWQPFRRPRDPLFLRGLFQGAGPAEAPTARRKMESGTVLLESKSSPLHLLHEMHELRLLGHLCDVTVSVEYQGVCEDFMAHKAVLAATSKFFKEVFLNEKRVDGTRTNVCLKEVQVVDFASFLEFVYTARVQVEEDRVQRMLEVAEKLKCWDLSETCFHLKKQMLESVLLESQNFFVSQEVEASSGPHVSVTPSSKASIPGEEAHSSGLVDTSDYLIERFDNDLLPEMPSRKCKEKLDKKKDVAKPPYPKIRRPSGRLAGRKVFVEIPKKKYTRRLREQQRSAEEAAENDRCSQNQSPDTERLETEPASKSEACSSGVKLEESQQKVEGEKEEEGKDGEKKSNFRCTVCEKAFLYEKSYLKHIRHHHGVATEVVYQCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTSLRMHERTHTGDRPYGCTKCEAKFSQPSALKTHMRIHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHAKIHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDGHTEQPDDEYASTKLSDRLLSFGENSHFNNLLEVQSNVPAMQENSSTDTACKAVVSQDALLTTTINELGELTPQPGSMTTHLPSLTNME", "length": 787 }, "evidence": [ { "id": "A0A8V0Z5W4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABI0NYU0-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "GZF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESGAVLLESKSSPINLLHEMHQLRLLGHLCDVTVSVEYQGVREEFMAHKAVLAATSKFFKEVFLNEKTVDGARTNVYLDEVQVADFASFLEFVYTAKVQVEEDRVQRMLEMAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEAEGSSGAQVTAALAPEAWAGMAPDGPLANGVASSLDPPAERIGNGLLPDLPPRKSREKPDKRKEVAKPPYPKLRRASGRLAGRKVFVEIPKKKYTRRLREQQKSVEQDMGGCGGPREPSPEALENEKEAVTKDEEDSGAGAGVEAAPPKVGRGEEGDEEEEEGEEGPGRRRSNFQCTRCEKAFLYEKSFLKHVRLHHGVATEVVHRCDTCGQTFANRCNLKGHQRHVHSSERHFPCELCGKKFKRKKDVKRHVVQVHEGGGERHQCQQCGKGLSSKTALRLHERTHTGHKPYGCSECPATFSQPSALKTHLRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCNACGRAFTDKSTLRRHTSIHDKTTPWKSFLVIVDGSPKNGDGHKTEQPDDEYAPSKLSDKLLSFAENGHFHNLATVQGSMPAMHEDSPADPACKSDGPVGSQDTLLATAISELSELTPQTERPTLRSLTHVD", "length": 714 }, "evidence": [ { "id": "A0A8V0Z5W4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZUU2-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVIVDYQGVREDFMAHKAVLAATSKFFKEVFLNEKRADGTRTNVYLSEVQVVDFASFLEFVYTARVRVKEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPAGEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRRLREQQKSAEEAAKNDKCPQDQSPDNERVEAEPASKSEACPASVEREESLQKVEGEKEEEEGKDGEEKKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDEGQKTEQPDEEYASPKLSDRLLSFGENSHFNNLLEVQGNVPAVQENSSTDTACKAVVSQDALLTTSISALGELTPQTVSMPAHLPSLTNME", "length": 707 }, "evidence": [ { "id": "A0A8V0Z5W4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4VBD9-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVSIENQGVHEDFMAHKAVLAATSKFFKEVFLNEKSADGTRTNVYLNEVQAVDFASFLEFVYTAKVRVEEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPGEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRRLREQQKSAEEAAENDKCPQDQSPDNERMETEPAAKSEACPASVELEESLQKVEGEKEEEEGKDGEEKKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDEGHKTEQPDDEYASPKLSDRLLSFGENSHFNNLLEVQGNVPAVQENSSTGAACKAVVSQDALLTTSISALGELTPQAVSMPAHLPSLTNME", "length": 706 }, "evidence": [ { "id": "A0A8V0Z5W4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H116-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "GZF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFFKEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDSLDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKYTRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEEEEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTMQENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME", "length": 711 }, "evidence": [ { "id": "A0A8V0Z5W4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 909, "end_pos": 911, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 104, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 330, "end_pos": 358, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 675, "end_pos": 677 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 909, "end_pos": 911 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5Y2-1", "uniprot_ac": "A0A8V0Z5Y2", "uniprot_id": "A0A8V0Z5Y2_CHICK", "mass": { "chemical_mass": 49451.0, "monoisotopic_mass": 49451.0 }, "refseq": {}, "gene_names": [ { "name": "GFRA4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ] } ], "protein_names": [ { "name": "GDNF family receptor alpha 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus 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"A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCSWPWGYGITEPFWQCLIYWCACKGMAEAVSSSRDCLQAGESCTNDPICSSKFRTLRQCIAGNGANKLGPDAKNQCRSTVTALLSSQLYGCKCKRGMKKEKHCLSVYWSIHHTLMEGMNVLESSPYEPFIRGFDYVRLASITAGSENEVTQVNRCLDAAKACNVDEMCQRLRTEYVSFCIRRLARADTCNRSKCHKALRKFFDRVPPEYTHELLFCPCEDTACAERRRQTIVPACSYESKEKPNCLAPLDSCRENYVCRSRYAEFQFNCQPSLQTASGCRRDSYAACLLAYTGIIGSPITPNYIDNSTSSIAPWCTCNASGNRQEECESFLHLFTDNVCLQNAIQAFGNGTYLNAATAPSISPTTQMYKQERNANRAAATLSENIFEHLQPTKVAGEERLLRGSTRLSSETSSPAAPCHQAASLLQLWLPPTLAVLSHFMM", "length": 443, "header": "tr|A0A8V0Z5Y2-1|A0A8V0Z5Y2_CHICK Isoform 1 of GDNF family receptor alpha 4 OS=Gallus gallus OX=9031 GN=GFRA4 PE=3 SV=1 CANONICAL=A0A8V0Z5Y2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2/entry#A0A8V0YY28-1", "sequence": { "sequence": 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Peptide", "id": "ENSGALP00010025962.1", "url": "https://www.ensembl.org/id/ENSGALP00010025962.1" } ] } }, { "isoform_ac": "A0A8V0Z5Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2/entry#A0A8V0Z5Y2-1", "sequence": { "sequence": "MVCSWPWGYGITEPFWQCLIYWCACKGMAEAVSSSRDCLQAGESCTNDPICSSKFRTLRQCIAGNGANKLGPDAKNQCRSTVTALLSSQLYGCKCKRGMKKEKHCLSVYWSIHHTLMEGMNVLESSPYEPFIRGFDYVRLASITAGSENEVTQVNRCLDAAKACNVDEMCQRLRTEYVSFCIRRLARADTCNRSKCHKALRKFFDRVPPEYTHELLFCPCEDTACAERRRQTIVPACSYESKEKPNCLAPLDSCRENYVCRSRYAEFQFNCQPSLQTASGCRRDSYAACLLAYTGIIGSPITPNYIDNSTSSIAPWCTCNASGNRQEECESFLHLFTDNVCLQNAIQAFGNGTYLNAATAPSISPTTQMYKQERNANRAAATLSENIFEHLQPTKVAGEERLLRGSTRLSSETSSPAAPCHQAASLLQLWLPPTLAVLSHFMM", "length": 443, "header": "tr|A0A8V0Z5Y2-1|A0A8V0Z5Y2_CHICK Isoform 1 of GDNF family receptor alpha 4 OS=Gallus gallus OX=9031 GN=GFRA4 PE=3 SV=1 CANONICAL=A0A8V0Z5Y2-1" }, "locus": { "chromosome": "4", "start_pos": 88932265, "end_pos": 88918789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", 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OX=9031 GN=GFRA4 PE=3 SV=1 CANONICAL=A0A8V0Z5Y2-1" }, "locus": { "chromosome": "4", "start_pos": 88984326, "end_pos": 88918789, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043647.1", "url": "https://www.ensembl.org/id/ENSGALT00010043647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025968.1", "url": "https://www.ensembl.org/id/ENSGALP00010025968.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8853659", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8853659", "resource": "Reactome", "description": "RET signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ], "pmid": "" }, { "name": "glial cell-derived neurotrophic factor receptor activity", "id": "GO:0016167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016167", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y2" }, { "id": "SM00907", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00907" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDNF/GAS1", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 117, "start_aa": "Cys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5D6-1", "uniprot_ac": "A0A8V0Z5D6", "uniprot_id": "A0A8V0Z5D6_CHICK", "mass": { "chemical_mass": 59408.0, "monoisotopic_mass": 59408.0 }, "refseq": {}, "gene_names": [ { "name": "SPTLC3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ] } ], "protein_names": [ { "name": "serine C-palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.50", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPTLC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6", "locus": { "chromosome": "3", "start_pos": 12485347, "end_pos": 12640650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018186", "url": "https://www.ensembl.org/id/ENSGALG00010018186" } ] } } ], "crossref": [ { "id": "A0A8V0Z5D6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06454", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06454", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768538", "url": "https://www.ncbi.nlm.nih.gov/gene/768538", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768538", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768538", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFGSNAY", "url": "https://omabrowser.org/oma/group/MFGSNAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYM5", "url": "https://www.orthodb.org/?gene=A0A8V0YYM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5D6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6E7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13693:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13693:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YYM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSAKKTFIEHFEQAPMYVAVLTFVGFGVGTVFGYLRDFMRAWGLEKRNVAQEREQQKTCWSNLHTIHQALYDFVPLYQDFENFYTRNLYVRIRDNWNRPICSVPGPQFDLMERVTDDYNWTFRFTGRTIKNVINMGSYNYLGFAETDPNALKTVAKELQRYGTGICSTRQEMGTLDKHVELENLVAKFLGVEDAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVYGQPRSRRAWRKIIILVEGIYSMEGSIVRLPEIVSLKNKYKAYLYLDEAHSIGAVGATGRGVVEYFGMNPNDVDVLMGTFTKSFGAAGGYIAGKKGLVDFLRTHSHSAVYATSMCPPVAEQIIRAMKCLMGLDGTTQGLQRVRQLGKNTRYFRRRLHEMGFIIYGNDDSPVVPLLLYMPGKIGAFARRMLEKNIGVVVVGFPATPITESRARFCVSAAHTREMLDTVLNALDELGDFLHLKYSRYSKSSHPELYEETRFEFED", "length": 524, "header": "tr|A0A8V0Z5D6-1|A0A8V0Z5D6_CHICK Isoform 1 of serine C-palmitoyltransferase OS=Gallus gallus OX=9031 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0A8V0Z5D6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6/entry#A0A8V0YYM5-1", "sequence": { "sequence": "MELSAKKTFIEHFEQAPMYVAVLTFVGFGVGTVFGYLRDFMRAWGLEKRNVAQEREQQKDFVPLYQDFENFYTRNLYVRIRDNWNRPICSVPGPQFDLMERVTDDYNWTFRFTGRTIKNVINMGSYNYLGFAETDPNALKTVAKELQRYGTGICSTRQEMGTLDKHVELENLVAKFLGVEDAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVYGQPRSRRAWRKIIILVEGIYSMEGSIVRLPEIVSLKNKYKAYLYLDEAHSIGAVGATGRGVVEYFGMNPNDVDVLMGTFTKSFGAAGGYIAGKKGLVDFLRTHSHSAVYATSMCPPVAEQIIRAMKCLMGLDGTTQGLQRVRQLGKNTRYFRRRLHEMGFIIYGNDDSPVVPLLLYMPGKIGAFARRMLEKNIGVVVVGFPATPITESRARFCVSAAHTREMLDTVLNALDELGDFLHLKYSRYSKSSHPELYEETRFEFED", "length": 510, "header": "tr|A0A8V0YYM5-1|A0A8V0Z5D6_CHICK Computationally mapped isoform of serine C-palmitoyltransferase OS=Gallus gallus OX=9031 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0A8V0Z5D6-1" }, "locus": { "chromosome": "3", "start_pos": 12535005, "end_pos": 12486275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043965.1", "url": "https://www.ensembl.org/id/ENSGALT00010043965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026144.1", "url": "https://www.ensembl.org/id/ENSGALP00010026144.1" } ] } }, { "isoform_ac": "A0A8V0Z5D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6/entry#A0A8V0Z5D6-1", "sequence": { "sequence": "MELSAKKTFIEHFEQAPMYVAVLTFVGFGVGTVFGYLRDFMRAWGLEKRNVAQEREQQKTCWSNLHTIHQALYDFVPLYQDFENFYTRNLYVRIRDNWNRPICSVPGPQFDLMERVTDDYNWTFRFTGRTIKNVINMGSYNYLGFAETDPNALKTVAKELQRYGTGICSTRQEMGTLDKHVELENLVAKFLGVEDAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVYGQPRSRRAWRKIIILVEGIYSMEGSIVRLPEIVSLKNKYKAYLYLDEAHSIGAVGATGRGVVEYFGMNPNDVDVLMGTFTKSFGAAGGYIAGKKGLVDFLRTHSHSAVYATSMCPPVAEQIIRAMKCLMGLDGTTQGLQRVRQLGKNTRYFRRRLHEMGFIIYGNDDSPVVPLLLYMPGKIGAFARRMLEKNIGVVVVGFPATPITESRARFCVSAAHTREMLDTVLNALDELGDFLHLKYSRYSKSSHPELYEETRFEFED", "length": 524, "header": "tr|A0A8V0Z5D6-1|A0A8V0Z5D6_CHICK Isoform 1 of serine C-palmitoyltransferase OS=Gallus gallus OX=9031 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0A8V0Z5D6-1" }, "locus": { "chromosome": "3", "start_pos": 12535005, "end_pos": 12486275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043951.1", "url": "https://www.ensembl.org/id/ENSGALT00010043951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026138.1", "url": "https://www.ensembl.org/id/ENSGALP00010026138.1" } ] } }, { "isoform_ac": "A0A8V0Z6E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6/entry#A0A8V0Z6E7-1", "sequence": { "sequence": "MELSAKKTFIEHFEQAPMYVAVLTFVGFGVGTVFGYLRDFMRAWGLEKRNVAQEREQQKDFVPLYQDFENFYTRNLYVRIRDNWNRPICSVPGPQFDLMERVTDDYNWTFRFTGRTIKNVINMGSYNYLGFAETDPNALKTVAKELQRYGTGICSTRQEMGTLDKHVELENLVAKFLGVEDAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVYGQPRSRRAWRKIIILVEGIYSMEGSIVRLPEIVSLKNKYKAYLYLDEAHSIGAVGATGRGVVEYFGMNPNDVDVLMGTFTKSFGAAGGYIAGKKGLVDFLRTHSHSAVYATSMCPPVAEQIIRAMKCLMGLDGTTQGKLRQLGKNTRYFRRRLHEMGFIIYGNDDSPVVPLLLYMPGKIGAFARRMLEKNIGVVVVGFPATPITESRARFCVSAAHTREMLDTVLNALDELGDFLHLKYSRYSKSSHPELYEETRFEFED", "length": 508, "header": "tr|A0A8V0Z6E7-1|A0A8V0Z6E7_CHICK Computationally mapped isoform of serine C-palmitoyltransferase OS=Gallus gallus OX=9031 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0A8V0Z5D6-1" }, "locus": { "chromosome": "3", "start_pos": 12535005, "end_pos": 12486275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043958.1", "url": "https://www.ensembl.org/id/ENSGALT00010043958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026142.1", "url": "https://www.ensembl.org/id/ENSGALP00010026142.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:768538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768538", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QER4-1", "protein_name": "serine C-palmitoyltransferase", "gene_name": "Sptlc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASLRGSVVTNGTLHNPKTQHSKWQSTDCVKNGIAKEAQQNRKPRFFDKPIFDSYPEPPLYVLVFTYMAYVIGTLFGYLRDFMRSLGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRVRDLWNQTVCSAPGPYFDMMEKVSDDRNWTFRHTGRVIKNVVNMGSYNYLGLAVKYDESMKSVKDTLEKYGVGVASTRHEMGTLDKHKELEDLMAKFLNVEAVMTFGMGFATNSMNIPILVGKGCLILSDEFNHTSIILGARLSGATIRPFKHNNVQSLEKLLRESIINGQPRTGRAWKKILIVVEGIYSMEGSIVNLPQIVALKKKYKAYLYIDEAHSIGATGSNCQGVRDLFGLAPEDVDVYMGTFTKSFAASGGYIAGKKELVDYVRIHSHSAAYGTSMSPVVAAQIIRSLRLITGEDGNLGGRQRIQQLTKNIKYFRQRLTEMGFIIYGDDYSPIIPVLLYMPAKISVFGRYLLKKKIGVVLVGFPATSLAEGRARFCLSSAHTRETLDEVLEVVDKLGDMLNVKYFPCKKSGRPALYNEKSFDNEASFDEVNMQPEA", "length": 563 }, "evidence": [ { "id": "A0A8V0Z5D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5D6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SBJ7-1", "protein_name": "serine C-palmitoyltransferase", "gene_name": "SPTLC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADPGGGAVCNGSVDIQSDCPNENCRRNGIVKEAQQNGNSNFYKPIVESFEEAPLHAMVFTYLGYGIVTLFGYLRDFLRNWGIEKCNAAVEREEQKDFVPLYQNFENFYTRNLYMRIRDNWNRPICSNPGALFDVMERVSDDYNWTFRSTGRIIKDVINMGSYNFLGLAAKYDESMRTVKDVLETYGIGVGSTRQEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNVQSLEKLLRDAIIYGQPRTRRAWKKILILVEGIYSMEGSIVYLPQIVALKKKYKAYLYIDEAHSIGSLGPTGRGVVEFFGMDPRDVDVCMGTFTKSFGASGGYLAGRKDLVDYLRAHSHSAAYATSMSPPVAEQIIRSMKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLSQLGFIIYGNEASPVVPLLLYMPAKVAAFARHLLNRYKIGVVVVGFPATPLAEARARFCISATHTREMLDKVLEALDEIGDLLHVKYSRHRKSARPELYDESSFELED", "length": 548 }, "evidence": [ { "id": "A0A8V0Z5D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5D6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NUV7-1", "protein_name": "Serine palmitoyltransferase 3", "gene_name": "SPTLC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANPGGGAVCNGKLHNHKKQSNGSQSRNCTKNGIVKEAQQNGKPHFYDKLIVESFEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHKKSARPELYDETSFELED", "length": 552 }, "evidence": [ { "id": "A0A8V0Z5D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5D6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine C-palmitoyltransferase activity", "id": "GO:0004758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" }, { "name": "serine palmitoyltransferase complex", "id": "GO:0017059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" }, { "name": "sphingosine biosynthetic process", "id": "GO:0046512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-428127", "name": "SPTLC complexes transfer acyl-CoA onto serine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y257-1", "A0A8V0Z5D6-1" ], "evidence": [ { "id": "R-GGA-428127", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428127" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y257", "gene_name": "SPTLC1", "activity": [ { "ec_number": "2.3.1.50", "activity": "L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA.", "evidence": [ { "id": "A0A8V0Y257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y257" } ] }, { "ec_number": "2.3.1.50", "activity": "", "evidence": [ { "id": "A0A8V0Y257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y257" } ] } ] }, { "uniprot_ac": "A0A8V0Z5D6", "gene_name": "SPTLC3", "activity": [ { "ec_number": "2.3.1.50", "activity": "L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA.", "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ] }, { "ec_number": "2.3.1.50", "activity": "", "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D6" }, { "id": "PF00155", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminotransferase class I/classII large", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 492, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.50", "ec_name": "L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA.", "evidence": [ { "id": "2.3.1.50", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.50" }, { "id": "2.3.1.50", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.50" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 226, "end_pos": 228 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5W0-1", "uniprot_ac": "A0A8V0Z5W0", "uniprot_id": "A0A8V0Z5W0_CHICK", "mass": { "chemical_mass": 197494.0, "monoisotopic_mass": 197494.0 }, "refseq": {}, "gene_names": [ { "name": "PSME4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ] } ], "protein_names": [ { "name": "Proteasome activator subunit 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0", "locus": { "chromosome": "3", "start_pos": 3188458, "end_pos": 3125733, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016938", "url": "https://www.ensembl.org/id/ENSGALG00010016938" } ] } } ], "crossref": [ { "id": "421218", "url": "https://www.ncbi.nlm.nih.gov/gene/421218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ECTQLVP", "url": "https://omabrowser.org/oma/group/ECTQLVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYM9", "url": "https://www.orthodb.org/?gene=A0A8V0YYM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0G8", "url": "https://www.orthodb.org/?gene=A0A8V0Z0G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W0", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32170:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32170:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16507", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16507", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQGFARLLINLLKKKELLSRDDLELPWRPLCEMLERILYSKTEHLGLNWFPKYFPEDATAEMLDEWRPLMCPFDVTMQKAITYFELFLPTTLPPELHHKGFKLWFSEFIGLWVSVQNLPQWEGHLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSNQVVVPRFLTNAYDVGHAVMWITAMMGGPSKLVQKHLSGLFNSIASFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPTWLTPVPDSHKLTDQDVTDFVECIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLEKTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSMLQERDDLSEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFKVALEKVFNFAISNIFETRVAGRMVADMCRAAVKCRPEESLKLFVPHCCNVITHLTVNDDVLRDEELDKELLWNLQLLSEITRVDGKKLLPYREQLGKILQRTLHLTCKQGYILSCNLLHHLLRSATLIYPTEYCSVPGGFDKPLSEYFPIKDWGKPGDLWNLDIQWHVPSSEEINFAFYLLDTFLQPELTKLEHYATGKLEMSRDDVQQCLAIVHNCLIGSGNILPPLKGERVAHLVPSLVSLEETKLYTGVEYDLSRENYRETIARVTRKLLRYILDNSEDDTKSLFLIIKIISDVLQFQGSHKHEFDSRWKSFNLVKKSMENRLQGKKQHIRALLIDRVMLQHELRTLTMEGCEYKTSHQEMIRDLLCLSTSSYGQVRSKAQQAFFTALGTYNFCCRDIIPLVLEFLRPDRQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIAQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFAVPEKCIQIAVMLQRSEHPSIDFTPLRSEEIQLGIQRQKEKNAEALRNYENLVNMLLDCVEQRNLPWKFEHISIGFLSLLLRDDRILPVRAIRFFVQCLNHDAIVVRKVAISAVAGVLKQLKRTHKKVPICPYEISGNPKPSSIQAGDRLDNQWLHYDSRSLPKTKEAWESCCFVEKTHWGYYTWPQTMTVYAPVEQQPKLGRRRDELTEAEQIIYDHFSDPKFVEQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNFDDAFLPVLQPHLERLVSDSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWKLLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAATKSPRVHEFTTRILENLKPLMEADEEIQNHVMEENGVGEQDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKMCLSLMSQGLLYPQQVPLVLQVLKQTARSNSWHARYTILTYLQTMVFYNLFIFLNNEEAVNDIRWLVIKLLEDEQLEVREMAATTLSGLLQCNFLTMDGPMQTHFEQLCKMRLPKKRKRDLGSVVDTIPSGDLVKRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1714, "header": "tr|A0A8V0Z5W0-1|A0A8V0Z5W0_CHICK Isoform 1 of Proteasome activator subunit 4 OS=Gallus gallus OX=9031 GN=PSME4 PE=1 SV=1 CANONICAL=A0A8V0Z5W0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0/entry#A0A8V0YYM9-1", "sequence": { "sequence": "MALPPPQKEIVYNKLLPYGERLEAEAARFLAQIKGNLARAVQLQELWPGGLFWTRKLSTKKELLSRDDLELPWRPLCEMLERILYSKTEHLGLNWFPNSYRPGMSSPKTFVLNVLHRCSVESVLKTLVKSCRPYFPEDATAEMLDEWRPLMCPFDVTMQKAITYFELFLPTTLPPELHHKGFKLWFSEFIGLWVSVQNLPQWEGHLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSNQVVVPRFLTNAYDVGHAVMWITAMMGGPSKLVQKHLSGLFNSIASFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPTWLTPVPDSHKLTDQDVTDFVECIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLEKTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSMLQERDDLSEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFKVALEKVFNFAISNIFETRVAGRMVADMCRAAVKCRPEESLKLFVPHCCNVITHLTVNDDVLRDEELDKELLWNLQLLSEITRVDGKKLLPYREQLGKILQRTLHLTCKQGYILSCNLLHHLLRSATLIYPTEYCSVPGGFDKPLSEYFPIKDWGKPGDLWNLDIQWHVPSSEEINFAFYLLDTFLQPELTKLEHYATGKLEMSRDDVQQCLAIVHNCLIGSGNILPPLKGERVAHLVPSLVSLEETKLYTGVEYDLSRENYRETIARVTRKLLRYILDNSEDDTKSLFLIIKIISDVLQFQGSHKHEFDSRWKSFNLVKKSMENRLQGKKQHIRALLIDRVMLQHELRTLTMEGCEYKTSHQEMIRDLLCLSTSSYGQVRSKAQQAFFTALGTYNFCCRDIIPLVLEFLRPDRQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIAQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFAVPEKCIQIAVMLQRSEHPSIDFTPLRSEEIQLGIQRQKEKNAEALRNYENLVNMLLDCVEQRNLPWKFEHISIGFLSLLLRDDRILPVRAIRFFVQCLNHDAIVVRKVAISAVAGVLKQLKRTHKKVPICPYEISGNPKPSSIQAGDRLDNQWLHYDSRSLPKTKEAWESCCFVEKTHWGYYTWPQTMTVYAPVEQQPKLGRRRDELTEAEQIIYDHFSDPKFVEQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNFDDAFLPVLQPHLERLVSDSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWKLLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAATKSPRVHEFTTRILENLKPLMEADEEIQNHVMEENGVGEQDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKMCLSLMSQGLLYPQQVPLVLQVLKQTARSNSWHARYTILTYLQTMVFYNLFIFLNNEEAVNDIRWLVIKLLEDEQLEVREMAATTLSGLLQCNFLTMDGPMQTHFEQLCKMRLPKKRKRDLGSVVDTIPSGDLVKRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1794, "header": "tr|A0A8V0YYM9-1|A0A8V0Z5W0_CHICK Computationally mapped isoform of Proteasome activator subunit 4 OS=Gallus gallus OX=9031 GN=PSME4 PE=1 SV=1 CANONICAL=A0A8V0Z5W0-1" }, "locus": { "chromosome": "3", "start_pos": 3188312, "end_pos": 3125827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040922.1", "url": "https://www.ensembl.org/id/ENSGALT00010040922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023886.1", "url": "https://www.ensembl.org/id/ENSGALP00010023886.1" } ] } }, { "isoform_ac": "A0A8V0Z0G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0/entry#A0A8V0Z0G8-1", "sequence": { "sequence": "MALPPPQKEIVYNKLLPYGERLEAEAARFLAQIKGNLARAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVTIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLCEMLERILYSKTEHLGLNWFPNSYRPGMSSPKTFVLNVLHRCSVESVLKTLVKSCRPYFPEDATAEMLDEWRPLMCPFDVTMQKAITYFELFLPTTLPPELHHKGFKLWFSEFIGLWVSVQNLPQWEGHLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSNQVVVPRFLTNAYDVGHAVMWITAMMGGPSKLVQKHLSGLFNSIASFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPTWLTPVPDSHKLTDQDVTDFVECIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLEKTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSMLQERDDLSEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFKVALEKVFNFAISNIFETRVAGRMVADMCRAAVKCRPEESLKLFVPHCCNVITHLTVNDDVLRDEELDKELLWNLQLLSEITRVDGKKLLPYREQLGKILQRTLHLTCKQGYILSCNLLHHLLRSATLIYPTEYCSVPGGFDKPLSEYFPIKDWGKPGDLWNLDIQWHVPSSEEINFAFYLLDTFLQPELTKLEHYATGKLEMSRDDVQQCLAIVHNCLIGSGNILPPLKGERVAHLVPSLVSLEETKLYTGVEYDLSRENYRETIARVTRKLLRYILDNSEDDTKSLFLIIKIISDVLQFQGSHKHEFDSRWKSFNLVKKSMENRLQGKKQHIRALLIDRVMLQHELRTLTMEGCEYKTSHQEMIRDLLCLSTSSYGQVRSKAQQAFFTALGTYNFCCRDIIPLVLEFLRPDRQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIAQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFAVPEKCIQIAVMLQRSEHPSIDFTPLRSEEIQLGIQRQKEKNAEALRNYENLVNMLLDCVEQRNLPWKFEHISIGFLSLLLRDDRILPVRAIRFFVQCLNHDAIVVRKVAISAVAGVLKQLKRTHKKVPICPYEISGNPKPSSIQAGDRLDNQWLHYDSRSLPKTKEAWESCCFVEKTHWGYYTWPQTMTVYAPVEQQPKLGRRRDELTEAEQIIYDHFSDPKFVEQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNFDDAFLPVLQPHLERLVSDSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWKLLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAATKSPRVHEFTTRILENLKPLMEADEEIQNHVMEENGVGEQDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKMCLSLMSQGLLYPQQVPLVLQVLKQTARSNSWHARYTILTYLQTMVFYNLFIFLNNEEAVNDIRWLVIKLLEDEQLEVREMAATTLSGLLQCNFLTMDGPMQTHFEQLCKMRLPKKRKRDLGSVVDTIPSGDLVKRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1841, "header": "tr|A0A8V0Z0G8-1|A0A8V0Z5W0_CHICK Computationally mapped isoform of Proteasome activator subunit 4 OS=Gallus gallus OX=9031 GN=PSME4 PE=1 SV=1 CANONICAL=A0A8V0Z5W0-1" }, "locus": { "chromosome": "3", "start_pos": 3188312, "end_pos": 3125827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040928.1", "url": "https://www.ensembl.org/id/ENSGALT00010040928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023892.1", "url": "https://www.ensembl.org/id/ENSGALP00010023892.1" } ] } }, { "isoform_ac": "A0A8V0Z5W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0/entry#A0A8V0Z5W0-1", "sequence": { "sequence": "MMQGFARLLINLLKKKELLSRDDLELPWRPLCEMLERILYSKTEHLGLNWFPKYFPEDATAEMLDEWRPLMCPFDVTMQKAITYFELFLPTTLPPELHHKGFKLWFSEFIGLWVSVQNLPQWEGHLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSNQVVVPRFLTNAYDVGHAVMWITAMMGGPSKLVQKHLSGLFNSIASFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPTWLTPVPDSHKLTDQDVTDFVECIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLEKTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSMLQERDDLSEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFKVALEKVFNFAISNIFETRVAGRMVADMCRAAVKCRPEESLKLFVPHCCNVITHLTVNDDVLRDEELDKELLWNLQLLSEITRVDGKKLLPYREQLGKILQRTLHLTCKQGYILSCNLLHHLLRSATLIYPTEYCSVPGGFDKPLSEYFPIKDWGKPGDLWNLDIQWHVPSSEEINFAFYLLDTFLQPELTKLEHYATGKLEMSRDDVQQCLAIVHNCLIGSGNILPPLKGERVAHLVPSLVSLEETKLYTGVEYDLSRENYRETIARVTRKLLRYILDNSEDDTKSLFLIIKIISDVLQFQGSHKHEFDSRWKSFNLVKKSMENRLQGKKQHIRALLIDRVMLQHELRTLTMEGCEYKTSHQEMIRDLLCLSTSSYGQVRSKAQQAFFTALGTYNFCCRDIIPLVLEFLRPDRQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIAQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFAVPEKCIQIAVMLQRSEHPSIDFTPLRSEEIQLGIQRQKEKNAEALRNYENLVNMLLDCVEQRNLPWKFEHISIGFLSLLLRDDRILPVRAIRFFVQCLNHDAIVVRKVAISAVAGVLKQLKRTHKKVPICPYEISGNPKPSSIQAGDRLDNQWLHYDSRSLPKTKEAWESCCFVEKTHWGYYTWPQTMTVYAPVEQQPKLGRRRDELTEAEQIIYDHFSDPKFVEQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNFDDAFLPVLQPHLERLVSDSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWKLLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAATKSPRVHEFTTRILENLKPLMEADEEIQNHVMEENGVGEQDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKMCLSLMSQGLLYPQQVPLVLQVLKQTARSNSWHARYTILTYLQTMVFYNLFIFLNNEEAVNDIRWLVIKLLEDEQLEVREMAATTLSGLLQCNFLTMDGPMQTHFEQLCKMRLPKKRKRDLGSVVDTIPSGDLVKRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1714, "header": "tr|A0A8V0Z5W0-1|A0A8V0Z5W0_CHICK Isoform 1 of Proteasome activator subunit 4 OS=Gallus gallus OX=9031 GN=PSME4 PE=1 SV=1 CANONICAL=A0A8V0Z5W0-1" }, "locus": { "chromosome": "3", "start_pos": 3188312, "end_pos": 3132104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040916.1", "url": "https://www.ensembl.org/id/ENSGALT00010040916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023880.1", "url": "https://www.ensembl.org/id/ENSGALP00010023880.1" } ] } }, { "isoform_ac": "A0A8V0Z5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0/entry#A0A8V0Z5Y3-1", "sequence": { "sequence": "MALPPPQKEIVYNKLLPYGERLEAEAARFLAQIKGNLARAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVTIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLCEMLERILYSKTEHLGLNWFPNSVESVLKTLVKSCRPYFPEDATAEMLDEWRPLMCPFDVTMQKAITYFELFLPTTLPPELHHKGFKLWFSEFIGLWVSVQNLPQWEGHLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSNQVVVPRFLTNAYDVGHAVMWITAMMGGPSKLVQKHLSGLFNSIASFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPTWLTPVPDSHKLTDQDVTDFVECIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLEKTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSMLQERDDLSEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFKVALEKVFNFAISNIFETRVAGRMVADMCRAAVKCRPEESLKLFVPHCCNVITHLTVNDDVLRDEELDKELLWNLQLLSEITRVDGKKLLPYREQLGKILQRTLHLTCKQGYILSCNLLHHLLRSATLIYPTEYCSVPGGFDKPLSEYFPIKDWGKPGDLWNLDIQWHVPSSEEINFAFYLLDTFLQPELTKLEHYATGKLEMSRDDVQQCLAIVHNCLIGSGNILPPLKGERVAHLVPSLVSLEETKLYTGVEYDLSRENYRETIARVTRKLLRYILDNSEDDTKSLFLIIKIISDVLQFQGSHKHEFDSRWKSFNLVKKSMENRLQGKKQHIRALLIDRVMLQHELRTLTMEGCEYKTSHQEMIRDLLCLSTSSYGQVRSKAQQAFFTALGTYNFCCRDIIPLVLEFLRPDRQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIAQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFAVPEKCIQIAVMLQRSEHPSIDFTPLRSEEIQLGIQRQKEKNAEALRNYENLVNMLLDCVEQRNLPWKFEHISIGFLSLLLRDDRILPVRAIRFFVQCLNHDAIVVRKVAISAVAGVLKQLKRTHKKVPICPYEISGNPKPSSIQAGDRLDNQWLHYDSRSLPKTKEAWESCCFVEKTHWGYYTWPQTMTVYAPVEQQPKLGRRRDELTEAEQIIYDHFSDPKFVEQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNFDDAFLPVLQPHLERLVSDSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWKLLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAATKSPRVHEFTTRILENLKPLMEADEEIQNHVMEENGVGEQDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKMCLSLMSQGLLYPQQVPLVLQVLKQTARSNSWHARYTILTYLQTMVFYNLFIFLNNEEAVNDIRWLVIKLLEDEQLEVREMAATTLSGLLQCNFLTMDGPMQTHFEQLCKMRLPKKRKRDLGSVVDTIPSGDLVKRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1821, "header": "tr|A0A8V0Z5Y3-1|A0A8V0Z5Y3_CHICK Computationally mapped isoform of Proteasome activator subunit 4 OS=Gallus gallus OX=9031 GN=PSME4 PE=1 SV=1 CANONICAL=A0A8V0Z5W0-1" }, "locus": { "chromosome": "3", "start_pos": 3188312, "end_pos": 3125827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040931.1", "url": "https://www.ensembl.org/id/ENSGALT00010040931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023895.1", "url": "https://www.ensembl.org/id/ENSGALP00010023895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9R9-1", "protein_name": "Proteasome activator complex subunit 4", "gene_name": "Psme4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPERAGGGEPPEPGGRPVLGPRAFVPQKEIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDMVERILYSKTEHLRLNSFPNSIENVLKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAVSYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNEEELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLQSFLQPELIKLQRCGDGELEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLVPSMVSLEETKLYTGLEHDLSKENHREVIASVIRKLLSHILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADAVRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPATVLAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIPEFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIIRLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQSHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1843 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287APQ3-1", "protein_name": "Proteasome activator complex subunit 4", "gene_name": "PSME4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPAERAGGGDPSEPGGRPSPNPRGFVPQKEIVYNKLLPYAEQLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDMVERILYSKTEHLGLNWFPNSVENVLKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFRLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPSSVVRRLHRERYKKPSWLTPVPDSHKLSDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLSCVIGVARSLVSGGKWFPQGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPDESLKLFVPHCCSVITQLTMNDDVLKDEELDKELLWSLQLLSEITRVDGKKLLLYKEQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVAFAFYLLDSFLQPELIKLQHCGDGELEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLVPSMVSLEETKLYTGLEYDLSRENYRETIARVIRKLLNHILNNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDKQDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSKAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPNSCVGIAELLQQSKNPSTNQIMLSSEEIKEGLKRQQEKNADALRNYENLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGYPKPTQIFAGDRPDNHWLHYDSKSIPRTKKEWESSCFVEKTHWGYYTWPQNMVVYAGMEEQPKLGRSREDLTEAEQIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTASPRVPEFTARILEKLKPLMDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLSNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGFVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1843 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JC97-1", "protein_name": "Proteasome activator subunit 4", "gene_name": "PA200", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MHLYNEWLPPPVAEETKKEKESFARVVRCVKELHRPDDPESVYATLKWISVIELFVRAKSELSVEDVSELVEIGLQIFHSSENKLYAQVRWGNVLVRLINKFRKKLSLKVQWRPLYDTLIHAHFSRSPGPEGWRLRQRHFMAVTSLIRSCRRFFPQGAASEIWSEFMSLLENPWHNSSFEGSGFVRLFLPTNPENQDFFSEKWIKNVLELWDSIPNCQFWNSQWTSVLARVIKNCSFIDWESYLPMLFSRFLNMFEVPVANGSGSYPFSVDVPRNTRFLFSNRTTTPSKSIAQSIVYFLKPGSSAHEQLEKLVNLLEQYYHPSNGGRWTYSLERFLLHLVIAFQKRLQREQQDPDSLPATCLGKPERVAFVGVVLKLIDRGQYSKNEHLSETVAAATSMLSYVEPSLVLPFVASRFHLALETTTATHQLKTAMMSVAFAGRSILQSSMSTAKSQDLGGDVDDRMFLDLIGISLSNALLGMDANDPPKTLATMQLIGSIFSNMAVLDDSSDDLSFMTMASFSEWLDEFLCRLIALLQHLEPNSVINEGLSSSATSGTFLVEDGPYYYCMLEILLGRLSGSLYNQALKKISKFVQTNILPGAIAEVGLLCCACVHSTPEEAVAQIVEPMLLAVISSLKEIPVNGYGGKGSAETLVSNKQDKQTLSPALEAAIDYQLKVLSVAITYGGSSLLPYKGLLIEAISSAFNSSSWKVNGAGDHLLRSLLGSLILYYPIDQYKCLSRHPAAPALEEWISTKASSKDEQVAHSRWHVPTQEETQFANELLDLHLQSALDDLLSICQSNIHSDAGDEKTHLKVTLLRIDSTLQGVLSCLPDFRPSPRHDMVEDLQFFIAGASGSCVGSAEIREKTAITIHAACKYLLEKKSDDSILLILIIRIMDALGNYGSLEYDEWSNHRQAWKLESAAIVEPPANFITEFNSKGKRRPRWALIDKAYMHNTWRSSQSSYHLFRTDGNFSPPEPLTFLVDDLLTLCLHNYETVRVLAGKSLIKLLKRWPQLLSKCVLSLTENLRKPDVQEYVVLGSCAILSSHSVLKHLTTDPKSFSSFLLGILSSSHHESMKSQKAIIELFVKYNIHFAGLSRNILRSLESHVEGSTSGDLVSQIGSMSFDSSSLHWRYNLMANRVLLLLVMSSRIDPSFSLKILDETAGHFLKNLKSQLPQTRILAISALNILLKESPHKMQGKDQPSVSSQETENANSSLDLALSQIFREEGFFKETFESLSHIHITDTDSSSRGNHGSSSFQSMADKSITRFYFEFSASWPRTPSWISLLGSDIFYPSFARIFKRLAQECGVPVLLALKSPLEEFCNAKERPKQCVAAEALAGVLHSDVNGLFNEWDSWIMVQLQNVILGQSVESIPEWAACIRYAVTGKGKQGTKIPVMRQQILDCIVAPLPPTATTTVVAKRYAFLSAALIELSPPKMPVTEVKLHIVLLDELICNMSHSSAQIREAIGVILSVLCSNIRLRMSYQQEYPTEEGKTDVDSQLKEENWFKLISAKASEAVKNIQQASISDSLDTSTDVDMGNAQSNGDSLDDVKWMETLFHFIISSFKSGRASYLLDVIAGFLYPVMSLQETSHKDLSILAKAAFELLKWRVFPESHLQKVIGVILSSADDSNWRIRSSTLTYLRTFMYRHTFILTHEDKQKIWKTVEKLLVDSQVEVREHAAAVLAGLMKGGDEDFAADFRDRSYAEANSIQKRRNRRKSSSTQSIAGVHGAVLGLVASVLSVPYDMPSWLPEHVTLLARFAGEPTPIKSTVTKAVAEFRRTHADTWNIQKDSFTEDQLEILADTSSSSSYFA", "length": 1811 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P43583-1", "protein_name": "Proteasome activator BLM10", "gene_name": "BLM10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTANNDDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPHSPLRARSATPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIEEFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDLFRLSNNTAENDLLGNDIADYDDAEGLEDELDEYFDLAGPDFNATGKITAKSATIVNVNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTNFTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSSKEDLQLFRLLLKHAHNAKPFFDKSKESLLVDTMNFLLSSLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVSANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVGVEFGEFGIFTDDQMTFMFNRLQGHLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKFVHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYYISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIRFIVMDKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLVQQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTKINQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSKELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELITFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDPRRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVLVMTHTLSGSSLLFDPDFNKYRTQSNLSYREKLILLKNIRENNCDPQELDIDIEQIRSGKDDEDYIESKDIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTPIAGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHKLYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNEPFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLYPDIYKPAQGTLVHCMKQLVGSYGVVINKIIPSLEKAIKDHDYMKIQVILNVLLIKKIHRKLMTDYKDIGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINLQVEAVKLAKKKKREYYLSLLVDLQDKLLDKLDNEKDMGWKIRMFILRFVTQIQSNLESKPDKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIISLSDYEYDITRAYKNEFNPSFVEILDTSTTSFPKTFTEEMNNFDNPKYFIDLRAYVGWLCWGRLMYVMSPKALKLNLRENELEVLKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFELCESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFEIWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRAPDVGKLFDELVFDHPYDQVRQAVAKLLTTLVQNQSNPSISDPTTLLEAERNDPDGLGLPLKSVPEKVDAYIKKQFEIIKNLEDSVVGLNPQQFIKTDYFYRTSTIFYWIKEMARGPNKVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSSNVALSSNQTKLQLAFIQHFLSAELLQLTEEEKNKILEFVVSNLYNEQFVEVRVRAASILSDIVHNWKEEQPLLSLIERFAKGLDVNKYTSKERQKLSKTDIKIHGNVLGLGAIISAFPYVFPLPPWIPKQLSNLSSWARTSGMTGQAAKNTISEFKKVRADTWKFDRASFNTEELEDLEGVLWRSYYA", "length": 2143 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14997-1", "protein_name": "Proteasome activator complex subunit 4", "gene_name": "PSME4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAERAGVGEPPEPGGRPEPGPRGFVPQKEIVYNKLLPYAERLDAESDLQLAQIKCNLGRAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPNSVENILKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMNDDVLNDEELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELVKLQHCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLVPSMVSLEETKLYTGLEYDLSRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVTQQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADALRNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTKKEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1843 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54DB2-1", "protein_name": "Proteasome activator complex subunit 4", "gene_name": "psmE4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MITFKTHKDQQLNNEFISFKKEDVENTGYYRYKNCKEFQQSKRLTDEMVRDLQREKIQQTTPPSYSSVVEQEKLDLVEEFFQSFDHSIMICNIGDINQLLHVFKHRIYEVQLQFTKQQYHYLIPRLFDLFIQFRAEDLGNVIIEFLSLLFSRGKKLIELKVNWRPLYKIFKENCEISKQYGSFDDHHSTIKLQQKFNVLIYNCQPFFGGDEVVDELLEEIGGYLVPHSNYIYFCANVLYLFTPTYHFSTLTSIPKWVDLYLNYYWSWIDFNKDWDERWLFIFSRAIKFGVNIDWTPILPILYTKMLKALDLGVGSPSMAHLKPVKHKIPEIFRLTREDRMEFHSIGKIIACLINSKTEKPAIQHFKTLISKIGLYFHPSNTGDWTTDLGEMTLSMSKSFLKRNKYIPYSELIIQEFLEIIYPSLTNALYSKKKNISLTIAKIMNEFSHVAPTYILPKIIDDFYSSVDREEVNRLIGGIEVVSTCLHPILFSPQFPEGKTHLITFMEIMIKCLDPIYTNKASGTFKFFNKLFSSILISDENQYIDQCENQIEENVTLSTSLFQEWSINFVDATINFLLQSSTKKGNFKRETVPNIFFRETMELFFGALSNEIFKAVLARLKSVFTNIFEPEYYKQLGEFLKSSTLRDPIQSISVFLPVFVNKLFIKHKITNGNNNNNNNNNNNCNNNYNSGIKYDIIGDLSDQELRLYITYIGYLVFKGGHGLVEFKDQLIDILTVLMESDNKIVLKATSKVIRKLIFSLTRIYPLNTRVVPQTIVNRKENHIKYWGSTDLSTILPIEWFEPNENDINFAKLLIDKFLKGTNDKLSNYINSLRTNDESNNNNNNNTYNRMKLLNLVKPIQSILRAATFLIKDTSNEIKQSKDEFRYQPKRSKFEHGEISFPEFSTLKQEIFNNYKETIQYLESKNINEEINVLRVISKTLFVMFYCRGDIIDHTHDHLFEKWKNHKKLKGRNYLVYKAFKSHLIRQKLNFQHMPITQLALDSMHFTLNLSVHNYRRVRETAQKAFVNILNMFNGSYEIILPICIDRLLDMKSDPEIKGISFIFQAKSISRKLKGNTEWVKKLQPMVAKQIDQKFKPNTRATFSELKKVLLIAKRLPILNYYQSKEMKSLNYYQGGDIVEDIVSNNHYSCYQKGINLNSLTEQQKQLIEKASKSNKEKVDKNRSNLLIALENMVTLSKSSEKNDSLPWRNHLFLLSSIIYYFSILFNPSPGLKDGFPYSEKYKDQEPIIKEVVLCIAKNSKCDFPFSRIYCLHSIANILAVQSNKNIEFCYQNYFGDNRFSTQEKIDLEIYGSSVDFEKYLFNLTKDDIITLLFTDGTNCTANSNAGRLFAYMSQDHEESSTNSFCQSMTNKNFTPSYPNTRASVSNKDFRSFNANYFFGLFQAVGGIKFIDTIKPIMEKLKGKSEKEDYFLLVEMLAGISRYISINDDLLGDERENIFSWVSNIAFISLTGCSNECTEAWTSAIRFITHNIRFDKIEWFSNLLFEVHKKTNNILAGSKSIKFLKAFLVEVTWKNKDLTEKLFEIAKTEFSNNYKQIRIEAMRLLSLLIIYQSDFSVHPPIIPQKETSILQGFIDIISNSSPPSSGSNSPLSHVNNGTNGIATTNSADVTMIDNSNSNNNNNDNNNNSNNNNSKNSKNAIKENILLLIYFLNSKNPVLVRSAPTLLKAIMSLTGDSNLEIAKDSSGCVYRMSQEFYFESGVIDQFITVLNQTLQSPSWKIRTSILQFVQVFFFNHSFIFSNQQTDSIVNTVLALTKDPQIEIREKSKATLASILISFKSDSNMVENLIKKAIKNLNVPDQSFIEKYSSLIILSSVVLAVPYNIPKYIPSVLQQLSRYSRNSHYKTAASTISEFWRTHKESWEEDKRQFTEEEAETILSTKVAPSYFA", "length": 1905 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5SSW2-1", "protein_name": "Proteasome activator complex subunit 4", "gene_name": "Psme4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPERAGGGEPPEPGGRPVLGPRAFVPQKEIVYNKLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDLVERILYSKTEHLRLNSFPNSIENVLKTLVKSCRPYFPADSTAEMLEEWRPLMCPFDVTMQKAISYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNEEELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSEYFPVKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELIKLQCCGDGELEMSRDDILQSLTIVHSCLIGSGNLLPPLKGEAVTNLVPSMVSLEETKLYTGLEHDLSRENYREVIASVIRKLLSHILDNSEDDTKSLFLIIKIIGDLLHFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADALRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPTKILAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMIEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIPEFTARVLEKLKPLTDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIICLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "length": 1843 }, "evidence": [ { "id": "A0A8V0Z5W0", "url": "https://omabrowser.org/oma/group/A0A8V0Z5W0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "spermatoproteasome complex", "id": "GO:1990111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "proteasomal ubiquitin-independent protein catabolic process", "id": "GO:0010499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "sperm DNA condensation", "id": "GO:0035092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidase activator activity", "id": "GO:0016504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1286, "end_pos": 1288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" }, { "id": "PF16507", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16507" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proteasome activator Blm10 middle HEAT repeats region", "eco_id": "ECO_0000259", "start_pos": 201, "end_pos": 697, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" }, { "id": "PF11919", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proteasome activator complex subunit 4 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1628, "end_pos": 1714, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W0" }, { "id": "PF23096", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23096" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proteasome activator complex subunit 4-like HEAT repeat-like", "eco_id": "ECO_0000259", "start_pos": 1056, "end_pos": 1340, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1286, "end_pos": 1288 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5H2-1", "uniprot_ac": "A0A8V0Z5H2", "uniprot_id": "A0A8V0Z5H2_CHICK", "mass": { "chemical_mass": 138281.0, "monoisotopic_mass": 138281.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP70", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 70", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2", "locus": { "chromosome": "14", "start_pos": 13105223, "end_pos": 13080590, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018215", "url": "https://www.ensembl.org/id/ENSGALG00010018215" } ] } } ], "crossref": [ { "id": "A0A8V0Z5H2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5H2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YYQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYR9", "url": "https://www.orthodb.org/?gene=A0A8V0YYR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5H2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6H8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44314", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44314", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44314:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44314:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATARAGNRMQSSRGVGHTLTPSLGGRDGSVAGPPSPQGPGKGCPHPRWRRDWHTLSCAKISRRLPISRDKLGCRGYGKPGAALPAPAAGEDPGSRPAASEPGSRGSRWFFGCSSAPPGLPPAPRALRWCSSSSSCRSSCDTQPSRSHVFAVFDSCRAMEGPSATKEFCPPDTSESQLSLRNVVQITVVKAQDLKSIKSDTSITLVRVEYNGVILGDSSKADVSPNGMANYNFTTSFEYSTDGPNSWVDIAQKPALLTVIEVLQKEKKQKEEKTMPLGQAVLDLLPLLQGQCSFTVLAPLYAASTSPSESLHPEAKCALEVSVCTKKPLLSSSQLSDGNFLSVTLEAAYSVPEAFVPTGPSQNYMACLQIPALGKKEVPLLFMNGILKLDGEKEPLPRPKKWSLANIMAPGALNIPNSFILGGPYEDEDGELNKTKDREFRIQAESMKRIVWDKERRCYLDPAAVLILKNRIAECQYWPVEVCRMPVTSSSKGKTSKADKGDEDRQIFFHGVAYVNMMPLLCPGVKRIRGAFRVFPYQDSEVLEKTKRQQSVLRDLRPQMGLIKEGSGTPGTNSSLSRAVPSKAQREDKEKMTREQEFNRRTSNTTKIQLSGVAEEAASVTSVSLDGKQYVEAGTFLVMEIKLDKALVPKRLQEELTRRVKEMIPPRPPLPPRTGGAKKAVEDYHNHVASIAVAILSEYHELFGKQLPDQGATDHQTLEEQRHQLNFELNSSGKYFAFKEQLKYAVVKIVREKYLKTTAFETQEQFQAFLSELYVYLVDQMHIALNQLLYEEAASPAPRIRMTDEQLWLFAREAEVNKDYKLASLYHQQRIAQDQHNIQYWLDYGAFCLLLEDTFKAQECFREALSLDPHHVRSLLLCGIVAVMLQHYEEAEIFFEDACCLEPSNVIAWTLSGLFCELQNNNIQAEMAFREAKKKLQVQQARERSISGQGKKQISATSVGSSSLGPEQPLPEGVPDGSAKELPEAGEELTLASVAQEEEAPASEAATEEPSPVSGHSKPPCTIFMKAVEFLTEVNAIQFVRMALAHELLSQQGGPSSAYYLALARTCLLKEEFSKCEECLCEAIRIDFLNPDVWAQKGHLCYLRRDLQEAKECYERTVSFVEDAADMHFVYLRLGSIYLEDKEYGKAKQIYLQACKSSASCLTWLGVGIACYRLGEMVEAEDALSEANALNNSNAEVWAYLALVCLQGGRQLEAEQCYKYASKLGLDDSALLQELHAAQQRLGFGDPSL", "length": 1249, "header": "tr|A0A8V0Z5H2-1|A0A8V0Z5H2_CHICK Isoform 1 of Cilia and flagella associated protein 70 OS=Gallus gallus OX=9031 GN=CFAP70 PE=1 SV=1 CANONICAL=A0A8V0Z5H2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2/entry#A0A8V0YYQ7-1", "sequence": { "sequence": "MATARAGNRMQSSRGVGHTLTPSLGGRDGSVAGPPSPQGPGKGCPHPRWRRDWHTLSCAKISRRLPISRDKLGCRGYGKPGAALPAPAAGEDPGSRPAASEPGSRGSRWFFGCSSAPPGLPPAPRALRWCSSSSSCRSSCDTQPSRSHVFAVFDSCRAMEGPSATKEFCPPDTSESQLSLRNVVQITVVKAQDLKSIKSDTSITLVRVEYNGVILGDSSKADVSPNGMANYNFTTSFEYSTDGPNSWVDIAQKPALLTVIEVLQKEKKQKEEKTMPLGQAVLDLLPLLQGQCSFTVLAPLYAASTSPSESLHPEAKCALEVSVCTKKPLLSSSQLSDGNFLSVTLEAAYSVPEAFVPTGPSQNYMACLQIPALGKKEVPLLFMNGILKLDGEKEPLPRPKKWSLANIMAPGALNIPNSFILGGPYEDEDGELNKTKDREFRIQAESMKRIVWDKERRCYLDPAAVLILKNRIAECQYWPVEVCRMPVTSSSKGKTSKADKGDEDRQIFFHGVAYVNMMPLLCPGVKRIRGAFRVFPYQDSEVLEKTKRQQSVLRDLRPQMGLIKEGSGTPGTNSSLSRAVPSKAQREDKEKMTREQEFNRRTSNTTKIQLSGVAEEAASVTSVSLDGKQYVEAGTFLVMEIKLDKALVPKRLQEELTRRVKEMIPPRPPLPPRTGGAKKAVEDYHNHVASIAVAILSEYHELFGKQLPDQGATDHQTLEEQRHQLNFELNSSGKYFAFKEQLKYAVVKIVREKYLKTTAFETQEQFQAFLSELYVYLVDQMHIALNQLLYEEAASPAPRIRMTDEQLWLFAREAEVNKDYKLASLYHQQRIAQDQHNIQYWLDYGAFCLLLEDTFKAQECFREALSLDPHHVRSLLLCGIVAVMLQHYEEAEIFFEDACCLEPSNVIAWTLSEGVPDGSAKELPEAGEELTLASVAQEEEAPASEAATEEPSPVSGHSKPPCTIFMKAVEFLTEVNAIQFVRMALAHELLSQQGGPSSAYYLALARTCLLKEEFSKCEECLCEAIRIDFLNPDVWAQKGHLCYLRRDLQEAKECYERTVSFVEDAADMHFVYLRLGSIYLEDKEYGKAKQIYLQACKSSASCLTWLGVGIACYRLGEMVEAEDALSEANALNNSNAEVWAYLALVCLQGGRQLEAEQCYKYASKLGLDDSALLQELHAAQQRLGFGDPSL", "length": 1190, "header": "tr|A0A8V0YYQ7-1|A0A8V0Z5H2_CHICK Computationally mapped isoform of Cilia and flagella associated protein 70 OS=Gallus gallus OX=9031 GN=CFAP70 PE=1 SV=1 CANONICAL=A0A8V0Z5H2-1" }, "locus": { "chromosome": "14", "start_pos": 13105167, "end_pos": 13081566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044022.1", "url": "https://www.ensembl.org/id/ENSGALT00010044022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026174.1", "url": "https://www.ensembl.org/id/ENSGALP00010026174.1" } ] } }, { "isoform_ac": "A0A8V0YYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2/entry#A0A8V0YYR9-1", "sequence": { "sequence": "MSKWCSSSSSCRSSCDTQPSRSHVFAVFDSCRAMEGPSATKEFCPPDTSESQLSLRNVVQITVVKAQDLKSIKSDTSITLVRVEYNGVILGDSSKADVSPNGMANYNFTTSFEYSTDGPNSWVDIAQKPALLTVIEVLQKEKKQKEEKTMPLGQAVLDLLPLLQGQCSFTVLAPLYAASTSPSESLHPEAKCALEVSVCTKKPLLSSSQLSDGNFLSVTLEAAYSVPEAFVPTGPSQNYMACLQIPALGKKEVPLLFMNGILKLDGEKEPLPRPKKWSLANIMAPGALNIPNSFILGGPYEDEDGELNKTKDREFRIQAESMKRIVWDKERRCYLDPAAVLILKNRIAECQYWPVEVCRMPVTSSSKGKTSKADKGDEDRQIFFHGVAYVNMMPLLCPGVKRIRGAFRVFPYQDSEVLEKTKRQQSVLRDLRPQMGLIKEGSGTPGTNSSLSRAVPSKAQREDKEKMTREQEFNRRTSNTTKIQLSGVAEEAASVTSVSLDGKQYVEAGTFLVMEIKLDKALVPKRLQEELTRRVKEMIPPRPPLPPRTGGAKKAVEDYHNHVASIAVAILSEYHELFGKQLPDQGATDHQTLEEQRHQLNFELNSSGKYFAFKEQLKYAVVKIVREKYLKTTAFETQEQFQAFLSELYVYLVDQMHIALNQLLYEEAASPAPRIRMTDEQLWLFAREAEVNKDYKLASLYHQQRIAQDQHNIQYWLDYGAFCLLLEDTFKAQECFREALSLDPHHVRSLLLCGIVAVMLQHYEEAEIFFEDACCLEPSNVIAWTLSGLFCELQNNNIQAEMAFREAKKKLQVQQARERSISGQGKKQISATSVGSSSLGPEQPLPEGVPDGSAKELPEAGEELTLASVAQEEEAPASEAATEEPSPVSGHSKPPCTIFMKAVEFLTEVNAIQFVRMALAHELLSQQGGPSSAYYLALARTCLLKEEFSKCEECLCEAIRIDFLNPDVWAQKGHLCYLRRDLQEAKECYERTVSFVEDAADMHFVYLRLGSIYLEDKEYGKAKQIYLQACKSSASCLTWLGVGIACYRLGEMVEAEDALSEANALNNSNAEVWAYLALVCLQVSAQQAPRPSLKNTACIPGVRTVGGAITAAPFPAAHRCLPSPPRAHPFPSPLCCFAGRAAAGGRAVLQIRLE", "length": 1154, "header": "tr|A0A8V0YYR9-1|A0A8V0Z5H2_CHICK Computationally mapped isoform of Cilia and flagella associated protein 70 OS=Gallus gallus OX=9031 GN=CFAP70 PE=1 SV=1 CANONICAL=A0A8V0Z5H2-1" }, "locus": { "chromosome": "14", "start_pos": 13104862, "end_pos": 13080835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044040.1", "url": "https://www.ensembl.org/id/ENSGALT00010044040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026184.1", "url": "https://www.ensembl.org/id/ENSGALP00010026184.1" } ] } }, { "isoform_ac": "A0A8V0Z5H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2/entry#A0A8V0Z5H2-1", "sequence": { "sequence": "MATARAGNRMQSSRGVGHTLTPSLGGRDGSVAGPPSPQGPGKGCPHPRWRRDWHTLSCAKISRRLPISRDKLGCRGYGKPGAALPAPAAGEDPGSRPAASEPGSRGSRWFFGCSSAPPGLPPAPRALRWCSSSSSCRSSCDTQPSRSHVFAVFDSCRAMEGPSATKEFCPPDTSESQLSLRNVVQITVVKAQDLKSIKSDTSITLVRVEYNGVILGDSSKADVSPNGMANYNFTTSFEYSTDGPNSWVDIAQKPALLTVIEVLQKEKKQKEEKTMPLGQAVLDLLPLLQGQCSFTVLAPLYAASTSPSESLHPEAKCALEVSVCTKKPLLSSSQLSDGNFLSVTLEAAYSVPEAFVPTGPSQNYMACLQIPALGKKEVPLLFMNGILKLDGEKEPLPRPKKWSLANIMAPGALNIPNSFILGGPYEDEDGELNKTKDREFRIQAESMKRIVWDKERRCYLDPAAVLILKNRIAECQYWPVEVCRMPVTSSSKGKTSKADKGDEDRQIFFHGVAYVNMMPLLCPGVKRIRGAFRVFPYQDSEVLEKTKRQQSVLRDLRPQMGLIKEGSGTPGTNSSLSRAVPSKAQREDKEKMTREQEFNRRTSNTTKIQLSGVAEEAASVTSVSLDGKQYVEAGTFLVMEIKLDKALVPKRLQEELTRRVKEMIPPRPPLPPRTGGAKKAVEDYHNHVASIAVAILSEYHELFGKQLPDQGATDHQTLEEQRHQLNFELNSSGKYFAFKEQLKYAVVKIVREKYLKTTAFETQEQFQAFLSELYVYLVDQMHIALNQLLYEEAASPAPRIRMTDEQLWLFAREAEVNKDYKLASLYHQQRIAQDQHNIQYWLDYGAFCLLLEDTFKAQECFREALSLDPHHVRSLLLCGIVAVMLQHYEEAEIFFEDACCLEPSNVIAWTLSGLFCELQNNNIQAEMAFREAKKKLQVQQARERSISGQGKKQISATSVGSSSLGPEQPLPEGVPDGSAKELPEAGEELTLASVAQEEEAPASEAATEEPSPVSGHSKPPCTIFMKAVEFLTEVNAIQFVRMALAHELLSQQGGPSSAYYLALARTCLLKEEFSKCEECLCEAIRIDFLNPDVWAQKGHLCYLRRDLQEAKECYERTVSFVEDAADMHFVYLRLGSIYLEDKEYGKAKQIYLQACKSSASCLTWLGVGIACYRLGEMVEAEDALSEANALNNSNAEVWAYLALVCLQGGRQLEAEQCYKYASKLGLDDSALLQELHAAQQRLGFGDPSL", "length": 1249, "header": "tr|A0A8V0Z5H2-1|A0A8V0Z5H2_CHICK Isoform 1 of Cilia and flagella associated protein 70 OS=Gallus gallus OX=9031 GN=CFAP70 PE=1 SV=1 CANONICAL=A0A8V0Z5H2-1" }, "locus": { "chromosome": "14", "start_pos": 13105167, "end_pos": 13081566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044029.1", "url": "https://www.ensembl.org/id/ENSGALT00010044029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026178.1", "url": "https://www.ensembl.org/id/ENSGALP00010026178.1" } ] } }, { "isoform_ac": "A0A8V0Z6H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2/entry#A0A8V0Z6H8-1", "sequence": { "sequence": "MATARAGNRMQSSRGVGHTLTPSLGGRDGSVAGPPSPQGPGKGCPHPRWRRDWHTLSCAKISRRLPISRDKLGCRGYGKPGAALPAPAAGEDPGSRPAASEPGSRGSRWFFGCSSAPPGLPPAPRALRWCSSSSSCRSSCDTQPSRSHVFAVFDSCRAMEGPSATKEFCPPDTSESQLSLRNVVQITVVKAQDLKSIKSDTSITLVRVEYNGVILGDSSKADVSPNGMANYNFTTSFEYSTDGPNSWVDIAQKPALLTVIEVLQKEKKQKEEKTMPLGQAVLDLLPLLQGQCSFTVLAPLYAASTSPSESLHPEAKCALEVSVCTKKPLLSSSQLSDGNFLSVTLEAAYSVPEAFVPTGPSQNYMACLQIPALGKKEVPLLFMNGILKLDGEKEPLPRPKKWSLANIMAPGALNIPNSFILGGPYEDEDGELNKTKDREFRIQAESMKRIVWDKERRCYLDPAAVLILKNRIAECQYWPVEVCRMPVTSSSKGKTSKADKGDEDRQIFFHGVAYVNMMPLLCPGVKRIRGAFRVFPYQDSEVLEKTKRQQSVLRDLRPQMGLIKEGSGTPGTNSSLSRAVPSKAQREDKEKMTREQEFNRRQYVEAGTFLVMEIKLDKALVPKRLQEELTRRVKEMIPPRPPLPPRTGGAKKAVEDYHNHVASIAVAILSEYHELFGKQLPDQGATDHQTLEEQRHQLNFELNSSGKYFAFKEQLKYAVVKIVREKYLKTTAFETQEQFQAFLSELYVYLVDQMHIALNQLLYEEAASPAPRIRMTDEQLWLFAREAEVNKDYKLASLYHQQRIAQDQHNIQYWLDYGAFCLLLEDTFKAQECFREALSLDPHHVRSLLLCGIVAVMLQHYEEAEIFFEDACCLEPSNVIAWTLSGLFCELQNNNIQAEMAFREAKKKLQVQQARERSISGQGKKQISATSVGSSSLGPEQPLPEGVPDGSAKELPEAGEELTLASVAQEEEAPASEAATEEPSPVSGHSKPPCTIFMKAVEFLTEVNAIQFVRMALAHELLSQQGGPSSAYYLALARTCLLKEEFSKCEECLCEAIRIDFLNPDVWAQKGHLCYLRRDLQEAKECYERTVSFVEDAADMHFVYLRLGSIYLEDKEYGKAKQIYLQACKSSASCLTWLGVGIACYRLGEMVEAEDALSEANALNNSNAEVWAYLALVCLQGGRQLEAEQCYKYASKLGLDDSALLQELHAAQQRLGFGDPSL", "length": 1222, "header": "tr|A0A8V0Z6H8-1|A0A8V0Z6H8_CHICK Computationally mapped isoform of Cilia and flagella associated protein 70 OS=Gallus gallus OX=9031 GN=CFAP70 PE=1 SV=1 CANONICAL=A0A8V0Z5H2-1" }, "locus": { "chromosome": "14", "start_pos": 13105167, "end_pos": 13081566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044017.1", "url": "https://www.ensembl.org/id/ENSGALT00010044017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026172.1", "url": "https://www.ensembl.org/id/ENSGALP00010026172.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1191, "end_pos": 1193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1191, "end_pos": 1193 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 730, "end_pos": 732 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z625-1", "uniprot_ac": "A0A8V0Z625", "uniprot_id": "A0A8V0Z625_CHICK", "mass": { "chemical_mass": 112407.0, "monoisotopic_mass": 112407.0 }, "refseq": {}, "gene_names": [ { "name": "SYNE3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ] } ], "protein_names": [ { "name": "Nesprin-3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#names_and_taxonomy" } ] }, { "name": "KASH domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#names_and_taxonomy" } ] }, { "name": "Nuclear envelope spectrin repeat protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z0L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0L1#function" }, { "database": "UniProtKB", "id": "ARBA00058355", "url": "https://www.uniprot.org/uniprotkb/ARBA00058355#function" }, { "database": "UniProtKB", "id": "A0A8V0YYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT3#function" }, { "database": "UniProtKB", "id": "A0A8V0YYT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT8#function" }, { "database": "UniProtKB", "id": "A0A8V0YZ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ62#function" }, { "database": "UniProtKB", "id": "A0A8V0YZ67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ67#function" }, { "database": "UniProtKB", "id": "A0A8V0Z629", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z629#function" }, { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625", "locus": { "chromosome": "5", "start_pos": 45508005, "end_pos": 45571887, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016970", "url": "https://www.ensembl.org/id/ENSGALG00010016970" } ] } } ], "crossref": [ { "id": "A0A8V0Z625", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z625", "database": "AlphaFoldDB", "categories": [] }, { "id": "423439", "url": "https://www.ncbi.nlm.nih.gov/gene/423439", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423439", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423439", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACCLEDQ", "url": "https://omabrowser.org/oma/group/ACCLEDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYT3", "url": "https://www.orthodb.org/?gene=A0A8V0YYT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYT8", "url": "https://www.orthodb.org/?gene=A0A8V0YYT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ62", "url": "https://www.orthodb.org/?gene=A0A8V0YZ62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ67", "url": "https://www.orthodb.org/?gene=A0A8V0YZ67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0L1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z625", "url": "https://www.orthodb.org/?gene=A0A8V0Z625", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z629", "url": "https://www.orthodb.org/?gene=A0A8V0Z629", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47535:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47535:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10541", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10541", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z625-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z629", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z629", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z629-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z629-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSNTTETVEGLRVSLNAMTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 974, "header": "tr|A0A8V0Z625-1|A0A8V0Z625_CHICK Isoform 1 of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0YYT3-1", "sequence": { "sequence": "MTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 955, "header": "tr|A0A8V0YYT3-1|A0A8V0Z625_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45548973, "end_pos": 45519378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040980.1", "url": "https://www.ensembl.org/id/ENSGALT00010040980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023943.1", "url": "https://www.ensembl.org/id/ENSGALP00010023943.1" } ] } }, { "isoform_ac": "A0A8V0YYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0YYT8-1", "sequence": { "sequence": "MKKWCVAANLLTPVSLNAMTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 973, "header": "tr|A0A8V0YYT8-1|A0A8V0Z625_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45571688, "end_pos": 45519378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040984.1", "url": "https://www.ensembl.org/id/ENSGALT00010040984.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023948.1", "url": "https://www.ensembl.org/id/ENSGALP00010023948.1" } ] } }, { "isoform_ac": "A0A8V0YZ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0YZ62-1", "sequence": { "sequence": "MTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPVGDSTQFAVADLCHCCFRLLQIASLNSAIHLCLIETFLGKQN", "length": 919, "header": "tr|A0A8V0YZ62-1|A0A8V0Z625_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45548973, "end_pos": 45530155, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040976.1", "url": "https://www.ensembl.org/id/ENSGALT00010040976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023940.1", "url": "https://www.ensembl.org/id/ENSGALP00010023940.1" } ] } }, { "isoform_ac": "A0A8V0YZ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0YZ67-1", "sequence": { "sequence": "MKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 882, "header": "tr|A0A8V0YZ67-1|A0A8V0Z625_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45548916, "end_pos": 45519378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040981.1", "url": "https://www.ensembl.org/id/ENSGALT00010040981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023945.1", "url": "https://www.ensembl.org/id/ENSGALP00010023945.1" } ] } }, { "isoform_ac": "A0A8V0Z0L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0Z0L1-1", "sequence": { "sequence": "MVSLNAMTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKV", "length": 897, "header": "tr|A0A8V0Z0L1-1|A0A8V0Z625_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45549137, "end_pos": 45529253, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040975.1", "url": "https://www.ensembl.org/id/ENSGALT00010040975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023939.1", "url": "https://www.ensembl.org/id/ENSGALP00010023939.1" } ] } }, { "isoform_ac": "A0A8V0Z625-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0Z625-1", "sequence": { "sequence": "MLSSNTTETVEGLRVSLNAMTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 974, "header": "tr|A0A8V0Z625-1|A0A8V0Z625_CHICK Isoform 1 of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45561452, "end_pos": 45519378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040978.1", "url": "https://www.ensembl.org/id/ENSGALT00010040978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023942.1", "url": "https://www.ensembl.org/id/ENSGALP00010023942.1" } ] } }, { "isoform_ac": "A0A8V0Z629-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625/entry#A0A8V0Z629-1", "sequence": { "sequence": "MAKTYVTVSLNAMTQQLQDEFDSSVENAEAWMKAIQERLSINDNTKGPRSALEARLRETEKIRDLEPEGMLKMDLILTKADAALHCVSEDEKHKVLSKLRHIKALWEETAIYITHCHSRIEWVWLHWSEYLKAQDEFYIWIHNMRVTLEPDIELQLGLKEKQWQLSHAQVLLNDVLNQSVLLETLLEEAASLFNRIGDPSVDEDAQKKMKVEYESIRKEAQNRVKLLEKITEEHKQYSANVNQFQSWLNGVTERLNCCIGEATKSSAEDSLKALKEIAKNIKNGAKKLKHLENQCADVIQNTSPLGAERLKDELDDLRKALEKLKLLSREEEQRLLKIQQSESAYKSQARQLEADIQEFRKDLQKLENDLDPGEGEKTEDELVAQWRKCNATRAVLAAEESKVERLKAQLKELLRFSQDVQPHADSVISVIRDYQSVKGKTSKMSADTETQLSRLFQNPLQSFERWKLTVQMLLETPEPALDQIEAALAESSQFKEKLMTLQLKKDLLNNILGEEKAKSFLEEVAEASKEREILHKSLLQSKSKLQNLILQHKDFDAAFAPLQKKLFAIKAKLDLENEPQPNLLGKKTQLQRLQMIQDDLAELAIQMEEVEKLVQSNATHRHEMNQLTSDIQALKRSLETMIQQTEEHVQKHWVFNDKLSDLQQWITATTEKIGSYQSADVKQGNESRVADLERWLAEFPDKEIQLHLVEAHGQLVMENSSPEETAHVQAELDQLKESWKSLKEMATGLLKRWQLNRPMADKKKITFVDSRHVSGPIFHCLDLNHKQEKTADGQRASSHSKLLHDFEEWLQGENTKLSKILAVNLSSTEEIKTRHKELEELQARVPDGQRRFEDLLHFHPVIGNSEDLEDLRYRWMLYKSKLKESMSSPITRSSEKPDRFRKKRSGGMCSFLHRVCWASLPLQLLLLFLLLLAFLLPLAEKTHSCTLANNFARSFNLMLRYNGPPPT", "length": 967, "header": "tr|A0A8V0Z629-1|A0A8V0Z629_CHICK Computationally mapped isoform of Nesprin-3 OS=Gallus gallus OX=9031 GN=SYNE3 PE=1 SV=1 CANONICAL=A0A8V0Z625-1" }, "locus": { "chromosome": "5", "start_pos": 45571211, "end_pos": 45519378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040983.1", "url": "https://www.ensembl.org/id/ENSGALT00010040983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023947.1", "url": "https://www.ensembl.org/id/ENSGALP00010023947.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423439", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423439", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZD24-1", "protein_name": "Nesprin-3", "gene_name": "Syne3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQQPQEDFDRSVEDAQAWMKAVQEQLQVNDNTKGPRAALEARLRETEKICQLEPEGCIKVELVLRAAEALLATCQEGQKPEILARLRDIKSQWEETVTYMTHCHSRIEWVWLHWSEYLLAQDEFYRWFQKMVVTLEPPVELQLGLKEKQWQLSHAQVLLHNVDNQAVLLDRLLEEAGSLFSRIGDPSVDEEAQKRMKAEYDAVKARAQHRVELLAQVAQDHEQYREDVSEFQLWLKALVEKVHGCLGRNCKLATEPRLSVLQDIAKDFPRGEESLNRLEEQAVGVIRNTSPLGAERISGELEEMRMVLEKLRVLWKEEEGRLQGLLQSKGACEQQIQQLEVELGELKKVLQRLAQQGLEPTVKTATEDELVAHWRLFSGTRAALASEEPRVDRLQTQLKELVIFPDLQSLSDSVVAAIQEYQSMKGKNARLHNATRTELWQRSQRSLNDLQLWKALAQRLLDITTSLPDLASIHTFLPQIEAALTESSRLKEQLSMLQLKTDLLGSIFGQERAATLLEQVTGSVRDRDLLHNSLLQRKSKLQSLLVQHKDFGVAFDPLHRKLLDLQARIQAEKGLQRDLPGKQVQLLRLQGLQEEGLDLGTQIEAVRSLAQGNSKYQHKVDQISSDQQALQRSLEDLVDRCQQNVREHCTFSHRLLELQLWITMATQTLESHQGDMRLWDAESQEAGLERLLSEIPEKEVQLSLLQALGQLVMKKSSPEGAAVVQEELRKLMESWQALRLLEESMLSLMRNEQLQRTEVDTGKKQVFTNNIPKAGFLINPQDPIPRRRHGVNPPEEHDLHEDHPQLLREFEQWLQAENSKLLRITTMRTATAKDLRTRELKLQELEARIPEGQILFENLLRHRPARDPSNELEDLRYRWMLYKSKLKGSGDLLTESSPGELTAFQKSRQQKRWRSPCSLLQKACRVALPLQLLLLLFLLLLFLLPAGEEERSCALANNFARSFALMLRYNGPPPT", "length": 976 }, "evidence": [ { "id": "A0A8V0Z625", "url": "https://omabrowser.org/oma/group/A0A8V0Z625/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4FZC9-1", "protein_name": "Nesprin-3", "gene_name": "Syne3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQQPQEDFERSVEDAQAWMKVIQEQLQVNDNTKGPRAALEARLRETEKICQLESEGMVKVELVLRAAEALLATCQEGQKPEILARLRDIKSQWEETVTYMTHCHSRIEWVWLHWSEYLLAQDEFYRWFQKMVVALEPPVELQLGLKEKQWQLSHAQVLLHNVDNQAVLLDRLLEEAGSLFSRIGDPSVDEDAQKRMKAEYDAVKARAQRRVDLLAQVAQDHEQYREDVNEFQLWLKAVVEKVHSCLGRNCKLATELRLSTLQDIAKDFPRGEESLKRLEEQAVGVIQNTSPLGAEKISGELEEMRGVLEKLRVLWKEEEGRLRGLLQSRGDCEQQIQQLEAELGDFKKSLQRLAQEGLEPTVKTATEDELVAQWRLFSGTRAALASEEPRVDRLQTQLKKLVTFPDLQSLSDSVVATIQEYQSMKGKNTRLHNATRAELWQRFQRPLNDLQLWKALAQRLLDITASLPDLASIHTFLPQIEAALTESSRLKEQLAMLQLKTDLLGSIFGQERAATLLEQVTSSVRDRDLLHNSLLQRKSKLQSLLVQHKDFGVAFDPLNRKLLDLQARIQAEKGLPRDLPGKQVQLLRLQGLQEEGLDLGTQIEAVRPLAHGNSKHQQKVDQISCDQQALQRSLEDLVDRCQQNVREHCTFSHRLSELQLWITMATQTLESHQGDVRLWDAESQEAGLETLLSEIPEKEVQVSLLQALGQLVMKKSSPEGATMVQEELRKLMESWQALRLLEENMLSLMRNQQLQRTEVDTGKKQVFTNNIPKAGFLINPQDPIPRRQHGANPLEGHDLPEDHPQLLRDFEQWLQAENSKLRRIITMRVATAKDLRTREVKLQELEARIPEGQHLFENLLRLRPARDPSNELEDLRYRWMLYKSKLKDSGHLLTESSPGELTAFQKSRRQKRWSPCSLLQKACRVALPLQLLLLLFLLLLFLLPAGEEERSCALANNFARSFALMLRYNGPPPT", "length": 975 }, "evidence": [ { "id": "A0A8V0Z625", "url": "https://omabrowser.org/oma/group/A0A8V0Z625/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMZ3-1", "protein_name": "Nesprin-3", "gene_name": "SYNE3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQQPQDDFDRSVEDAQAWMKAVQDQLQVNDNTQGPRAALEARLWETEKICQLEPEGRVRVDLVLRMAEALLACCPGDQKPGILARLKDIKAQWEETVTYMTHCHSRIEWVWLHWSEYLLARDEFYRWFQKMMVTLEPHIELQLGLKEKQWQLSHAQVLLHNVDNQAVLLDRLLEEAASLFNRIGDPSVDEDAQKRMKAEYDAVKAKAQKRVDLLEQVAREHEEYQAGVDEFQLWLKAVVEKVNGCLGRNCKLPITQRLSTLQDIAKDFPRGEESLETLEEQSAGVIRNTSPLGAEKITGELEEMRKVLEKLRALWEEEEERLRGLLRSRGAWEQQIKQLEAELSEFRMVLQRLAQEGLQPAAKAGTEDELVAHWRRYSATRAALASEEPRVDRLQAQLKELIVFPHNLKPLSDSVIATIQEYQSLKVKSARLRNAAAVELWQHFQRPLQDLQLWKALAQRLLEVTASLPDLPSLHTFLPQIEAALMESSRLKELLTMLQLKKDLLIGIFGQERATALLEQVAGSMRDRDLLHNSLLQRKSKLQSLLAQHKDFGAAFEPLQRKLLDLQVRVQAEKGLQRDLPGKQAQLSRLQGLQEEGLDLGAQMEAARPLVQENPNHQHKMDQLSSDFQALQRSLEDLVDRCRQSVQEHCTFSHQLLELRQWIVVTTQKLEAHRGEAGPGDAESQEAEFERLVAEFPEKEAQLSLVEAQGWLVMEKSSPEGAAVVQEELRELAESWRALRLLEESLLSLIRNWHLQRMEVDSGKKMVFTNNIPKSGFLINPMDPIPRHRRRANLLQEEEGSHEDFSQLLRNFGQWLQVENSKLVRIIAMRTSTAEDLRTRKSKLQELEARVPEGQHLFENLLRLGPARGTSDELEDLRYQWMLYKSKLKDSGHLLTQSSPGEPTGFQKTRRWRGLGSLFRRACCVALPLQLLLLLFLLLLFLLPIREEDRSCTLANNFARSFTLMLRYNGPPPT", "length": 975 }, "evidence": [ { "id": "A0A8V0Z625", "url": "https://omabrowser.org/oma/group/A0A8V0Z625/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WGA9-1", "protein_name": "Nesprin-3", "gene_name": "syne3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTQQEQHEFRESLEEARSWMQAIQERLKQNDDTKGPRSALEVRLRETEKIHSLEPDGQVKMDRVLVASEALLRNGDEELKNQTHCKLKDLKAFYDDTLTYIIHCHSRIEWVWLHWSEYLKAHEEFGLWLEKMHRSLEPLLEMQLGLQEKLWQVDHLRVLHSDIQGQAQFLERLLDEAAALFNRTGDPSVDEQTQQGLQEAYNHIRDRAQERLTLAQKIAEEHQQYQSCVHKFQSWLVSKTEEVSRFSDVDDSTQNRLKALQDLGASIAKEELTLQHIEKLSEAVKANTSPAGAEKITQEIEELRLAWQRLRQTLLELKEELQISLDSENEYSERCKELWADLAKLRTLVQKLSGDLESRDGERTEEHMVAQWKMHTGVRNKLIAQEPSVEELKSRLKELFRFPQDSKSLSDEVLAVVKEYQSVKGRSFRLSSESETALRQILQDPLHGFSQWSQLVSQVLEASSDVTEFSHIALLVQNIEKLLKNSVQLQERLSLLQVKSDLLSAVFGQEKAEDLLGELSGDMRKRELLHSQLQQRKNRLQGLISKTKDFSNAYDSIHTKLSSIKDQFVSTDGLQPDILAKKSQADQLRVIRKDLEECEAHIIALETLVSSNPTNRTKFERLYADWRLLYKALRMKVNESEENIGEHESFHENILNMEKWLMIMKQKLDSFRGSEGEWSIDNRQHEAERALGEFPEKELQLHQTEAQGHTVLAKTSEEGKVHILQDLKRLRESWMSLHTLSLNLYRLLQTTEFQDRWADGHQQGLSSDFEEGFITGDKRPDPLLRFHHEAESTGLQELERSTEADQDLIPAIVLGSIPSPRDSEVWRRERSVLDQSLDDEVDAVTSGVNRTVNRKKMQMEMKGGGDLVGSAGWTGDWVTEHMTSSGIDELDMHGRYETEPEVAQKRMKPSQIRHDDTLTGSQGPRRPADTEAQRSQFEAWLHKQNDKLTGILSNQRSLSAKELRIRQNTLKDLRAGVVWGQSQFQKLLEDQQHRSVEDMELEELRYRWMLYKSKLKEAADLKESVGGQIQEHVRSGKASSGPGFLYRVCRVALPLQLLLLALLLLAFLLPMMDEGTSCSLANNFARSFNIMLRYDGPPPT", "length": 1100 }, "evidence": [ { "id": "A0A8V0Z625", "url": "https://omabrowser.org/oma/group/A0A8V0Z625/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "establishment of protein localization to membrane", "id": "GO:0090150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z625", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z625" }, { "id": "PS51049", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51049" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KASH", "eco_id": "ECO_0000259", "start_pos": 916, "end_pos": 974, "start_aa": "Cys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 831, "end_pos": 833 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V0Z5K7", "locus": { "chromosome": "3", "start_pos": 13234259, "end_pos": 13312110, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018263", "url": "https://www.ensembl.org/id/ENSGALG00010018263" } ] } } ], "crossref": [ { "id": "A0A8V0Z5K7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "416738", "url": "https://www.ncbi.nlm.nih.gov/gene/416738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYU3", "url": "https://www.orthodb.org/?gene=A0A8V0YYU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z521", "url": "https://www.orthodb.org/?gene=A0A8V0Z521", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5K7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28557:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28557:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z521", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z521", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z521-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z521-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDKFVIKCGNFAVLVDVHILPEGSNKDTSWFSDQEKEVCTCLEEVVVSRIKHYLEAPKQRGQWKSMEHASSSPLFVTANNFHITAYFMKRWVNLRCALGKHYRELRMFPDKFVVCISKLEFNPSAWTCENGALKEVSNGTSEYFAESAENRKLKLSLNEQIKQDILKEIVKRTKKGKNSVSKPQTSKDSKKVDLGSLGSQTGNRKNDCQTSPGPQSEVKWRSTGRLKNCINTAESNLEFPVLELENNVNQRQPEDASSQQKPHFVEQLKSRLLSKNSPCSYESALLGPKQNQKTTETQAQQKSCSSEEKLDLFKEISSEEAPLIPSNTERSKCSDDHLGLFLEEKTPLNSRLFSKQDLTEIASDEELITFGKNLSRPLPMRTNQNEPGTATEELPVVPSSSYLEMQAVSSEQLIQKRKKEGEDGLRKLKLRRLKKP", "length": 438, "header": "tr|A0A8V0Z5K7-1|A0A8V0Z5K7_CHICK Isoform 1 of SLX4 interacting protein OS=Gallus gallus OX=9031 GN=SLX4IP PE=4 SV=1 CANONICAL=A0A8V0Z5K7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K7/entry#A0A8V0YYU3-1", "sequence": { "sequence": "MCGNFAVLVDVHILPEGSNKDTSWFSDQEKEEVCTCLEEVVVSRIKHYLEAPKQRGQWKSMEHASSSPLFVTANNFHITAYFMKRWVNLRCALGKHYRELRMFPDKFVVCISKLEFNPSAWTCENGALKEVSNGTSEYFAESAENRKLKLSLNEQIKQDILKEIVKRTKKGKNSVSKPQTSKDSKKVDLGSLGSQTGNRKNDCQTSPGPQSEVKWRSTGRLKNCINTAESNLEFPVLELENNVNQRQPEDASSQQKPHFVEQLKSRLLSKNSPCSYESALLGPKQNQKTTETQAQQKSCSSEEKLDLFKEISSEEAPLIPSNTERSKCSDDHLGLFLEEKTPLNSRLFSKQDLTEIASDEELITFGKNLSRPLPMRTNQNEPGTATEELPVVPSSSYLEMQAVSSEQLIQKRKKEGEDGLRKLKLRRLKKP", "length": 431, "header": "tr|A0A8V0YYU3-1|A0A8V0Z5K7_CHICK Computationally mapped isoform of SLX4 interacting protein OS=Gallus gallus OX=9031 GN=SLX4IP PE=4 SV=1 CANONICAL=A0A8V0Z5K7-1" }, "locus": { "chromosome": "3", "start_pos": 13276679, "end_pos": 13235605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044086.1", "url": "https://www.ensembl.org/id/ENSGALT00010044086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026205.1", "url": "https://www.ensembl.org/id/ENSGALP00010026205.1" } ] } }, { "isoform_ac": "A0A8V0Z521-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K7/entry#A0A8V0Z521-1", "sequence": { "sequence": "MASDKFVIKCGNFAVLVDVHILPEGSNKDTSWFSDQEKEEVCTCLEEVVVSRIKHYLEAPKQRGQWKSMEHASSSPLFVTANNFHITAYFMKRWVNLRCALGKHYRELRMFPDKFVVCISKLEFNPSAWTCENGALKEVSNGTSEYFAESAENRKLKLSLNEQIKQDILKEIVKRTKKGKNSVSKPQTSKDSKKVDLGSLGSQTGNRKNDCQTSPGPQSEVKWRSTGRLKNCINTAESNLEFPVLELENNVNQRQPEDASSQQKPHFVEQLKSRLLSKNSPCSYESALLGPKQNQKTTETQAQQKSCSSEEKLDLFKEISSEEAPLIPSNTERSKCSDDHLGLFLEEKTPLNSRLFSKQDLTEIASDEELITFGKNLSRPLPMRTNQNEPGTATEELPVVPSSSYLEMQAVSSEQLIQKRKKEACLHVTHSALQ", "length": 434, "header": "tr|A0A8V0Z521-1|A0A8V0Z521_CHICK Computationally mapped isoform of SLX4 interacting protein OS=Gallus gallus OX=9031 GN=SLX4IP PE=4 SV=1 CANONICAL=A0A8V0Z5K7-1" }, "locus": { "chromosome": "3", "start_pos": 13306022, "end_pos": 13234366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044102.1", "url": "https://www.ensembl.org/id/ENSGALT00010044102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026219.1", "url": "https://www.ensembl.org/id/ENSGALP00010026219.1" } ] } }, { "isoform_ac": "A0A8V0Z5K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K7/entry#A0A8V0Z5K7-1", "sequence": { "sequence": "MASDKFVIKCGNFAVLVDVHILPEGSNKDTSWFSDQEKEVCTCLEEVVVSRIKHYLEAPKQRGQWKSMEHASSSPLFVTANNFHITAYFMKRWVNLRCALGKHYRELRMFPDKFVVCISKLEFNPSAWTCENGALKEVSNGTSEYFAESAENRKLKLSLNEQIKQDILKEIVKRTKKGKNSVSKPQTSKDSKKVDLGSLGSQTGNRKNDCQTSPGPQSEVKWRSTGRLKNCINTAESNLEFPVLELENNVNQRQPEDASSQQKPHFVEQLKSRLLSKNSPCSYESALLGPKQNQKTTETQAQQKSCSSEEKLDLFKEISSEEAPLIPSNTERSKCSDDHLGLFLEEKTPLNSRLFSKQDLTEIASDEELITFGKNLSRPLPMRTNQNEPGTATEELPVVPSSSYLEMQAVSSEQLIQKRKKEGEDGLRKLKLRRLKKP", "length": 438, "header": "tr|A0A8V0Z5K7-1|A0A8V0Z5K7_CHICK Isoform 1 of SLX4 interacting protein OS=Gallus gallus OX=9031 GN=SLX4IP PE=4 SV=1 CANONICAL=A0A8V0Z5K7-1" }, "locus": { "chromosome": "3", "start_pos": 13306022, "end_pos": 13235605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044099.1", "url": "https://www.ensembl.org/id/ENSGALT00010044099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026216.1", "url": "https://www.ensembl.org/id/ENSGALP00010026216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 375, "end_pos": 377 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5M6-1", "uniprot_ac": "A0A8V0Z5M6", "uniprot_id": "A0A8V0Z5M6_CHICK", "mass": { "chemical_mass": 67476.0, "monoisotopic_mass": 67476.0 }, "refseq": { "ac": "XP_015133994", "name": "protein POF1B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133994" }, "gene_names": [ { "name": "POF1B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ] }, { "name": "POF1B", "type": "synonym", "evidence": [ { "id": "XP_015133994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133994" } ] } ], "protein_names": [ { "name": "POF1B actin binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6/entry#names_and_taxonomy" } ] }, { "name": "protein POF1B", "type": "synonym", "evidence": [ { "id": "XP_015133994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133994" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POF1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6", "locus": { "chromosome": "4", "start_pos": 8631219, "end_pos": 8614263, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018283", "url": "https://www.ensembl.org/id/ENSGALG00010018283" } ] } } ], "crossref": [ { "id": "A0A8V0Z5M6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5M6", "database": "AlphaFoldDB", "categories": [] }, { "id": "422268", "url": "https://www.ncbi.nlm.nih.gov/gene/422268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422268", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422268", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHYYRRQ", "url": "https://omabrowser.org/oma/group/HHYYRRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYX4", "url": "https://www.orthodb.org/?gene=A0A8V0YYX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5M6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015133994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YYX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGGQQQLQPLALPPHLQQQQHHYYRRQQHYSTLPAPRRPCREPPPCPEPPPCPETPPCREPPACPEPPLPPPCFEPPAPQRQESGPAFDRVRTYGPGCRRVGSSCSSRAASPLECSHGHQQLSAGCQPPPQGTIRRIIIENPEQEPLSPFLRGGNFCPGNNVIYEKTIRKYELLNPHQEKQYQFSHQCQVPQPSDQCRAFQPCQQPEQPPVTHQCQQTQTSSPCEVLPVSVTDDCRGNTVRRVTVQTCEQENNDQLDCRYFGELLAELNRKTNDLYSCLLQHVEKIGGRNHDIEFTSQTEDIEELIPKGLSEATKQQIRYLLQMRVTSDKSLRLVLSTFKNLREELCHLQDDLGKLETDNVLLKKDLAFKETQVKEYETMLCSLRENNRQQQQGLRESTARCRSLEEQLLSLRLSEGEKDCQLKELECSKRALDQEIQSLKLQICSSPTVQTTTDELSSRYVEMINNLREDKDREIRSLRSQLCQFQQDISRQEGNNSDLQIKLHELTAMLEEKDVCIKQQQEELFRLKHERVSSSQSPGVTAVITKKYRNQYPILGLLSDDYKVTSPVNKSQTIVIERTGEIWKHE", "length": 588, "header": "tr|A0A8V0Z5M6-1|A0A8V0Z5M6_CHICK Isoform 1 of POF1B actin binding protein OS=Gallus gallus OX=9031 GN=POF1B PE=1 SV=1 CANONICAL=A0A8V0Z5M6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6/entry#A0A8V0YYX4-1", "sequence": { "sequence": "LRWRPPSARSGAERLGAAPRPCPLPPRRCRQVRLSRAQRGVCAVRSLRIRSAFPPKLPYKTRLGGLPRGQPGPQRERHRGLLGREERAGGVCKQRALVPGTIRRIIIENPEQEPLSPFLRGGNFCPGNNVIYEKTIRKYELLNPHQEKQYQFSHQCQVPQPSDQCRAFQPCQQPEQPPVTHQCQQTQTSSPCEVLPVSVTDDCRGNTVRRVTVQTCEQENNDQLDCRYFGELLAELNRKTNDLYSCLLQHVEKIGGRNHDIEFTSQTEDIEELIPKGLSEATKQQIRYLLQMRVTSDKSLRLVLSTFKNLREELCHLQDDLGKLETDNVLLKKDLAFKETQVKEYETMLCSLRENNRQQQQGLRESTARCRSLEEQLLSLRLSEGEKDCQLKELECSKRALDQEIQSLKLQICSSPTVQTTTDELSSRYVEMINNLREDKDREIRSLRSQLCQFQQDISRQEGNNSDLQIKLHELTAMLEEKDVCIKQQQEELFRLKHERVSSSQSPGVTAVITKKYRNQYPILGLLSDDYKVTSPVNKSQTIVIERTGEIWKHE", "length": 555, "header": "tr|A0A8V0YYX4-1|A0A8V0Z5M6_CHICK Computationally mapped isoform of POF1B actin binding protein OS=Gallus gallus OX=9031 GN=POF1B PE=1 SV=1 CANONICAL=A0A8V0Z5M6-1" }, "locus": { "chromosome": "4", "start_pos": 8629980, "end_pos": 8614762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044122.1", "url": "https://www.ensembl.org/id/ENSGALT00010044122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026232.1", "url": "https://www.ensembl.org/id/ENSGALP00010026232.1" } ] } }, { "isoform_ac": "A0A8V0Z5M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6/entry#A0A8V0Z5M6-1", "sequence": { "sequence": "MLGGQQQLQPLALPPHLQQQQHHYYRRQQHYSTLPAPRRPCREPPPCPEPPPCPETPPCREPPACPEPPLPPPCFEPPAPQRQESGPAFDRVRTYGPGCRRVGSSCSSRAASPLECSHGHQQLSAGCQPPPQGTIRRIIIENPEQEPLSPFLRGGNFCPGNNVIYEKTIRKYELLNPHQEKQYQFSHQCQVPQPSDQCRAFQPCQQPEQPPVTHQCQQTQTSSPCEVLPVSVTDDCRGNTVRRVTVQTCEQENNDQLDCRYFGELLAELNRKTNDLYSCLLQHVEKIGGRNHDIEFTSQTEDIEELIPKGLSEATKQQIRYLLQMRVTSDKSLRLVLSTFKNLREELCHLQDDLGKLETDNVLLKKDLAFKETQVKEYETMLCSLRENNRQQQQGLRESTARCRSLEEQLLSLRLSEGEKDCQLKELECSKRALDQEIQSLKLQICSSPTVQTTTDELSSRYVEMINNLREDKDREIRSLRSQLCQFQQDISRQEGNNSDLQIKLHELTAMLEEKDVCIKQQQEELFRLKHERVSSSQSPGVTAVITKKYRNQYPILGLLSDDYKVTSPVNKSQTIVIERTGEIWKHE", "length": 588, "header": "tr|A0A8V0Z5M6-1|A0A8V0Z5M6_CHICK Isoform 1 of POF1B actin binding protein OS=Gallus gallus OX=9031 GN=POF1B PE=1 SV=1 CANONICAL=A0A8V0Z5M6-1" }, "locus": { "chromosome": "4", "start_pos": 8629980, "end_pos": 8614326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044126.1", "url": "https://www.ensembl.org/id/ENSGALT00010044126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026236.1", "url": "https://www.ensembl.org/id/ENSGALP00010026236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422268", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422268", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWE3-1", "protein_name": "POF1B, actin binding protein", "gene_name": "Pof1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPDQEPLSPFLRGGQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNVGHELCHGGPSQIHEQLIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFETADTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQIKEYEELLASVRANNRQQQQGLQDSSSKCQTLEENNLSLRHTLSDMEYRLKELEYCKRNLEQENKNLRIQVSETCTGSMLQGKMDEIGNHYMEMVKNLRLEKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSGGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "A0A8V0Z5M6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5M6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1P8-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTLKISACAPSTLHLAPTTEQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 589 }, "evidence": [ { "id": "A0A8V0Z5M6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5M6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X748-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSSSYSSEMSSSSCGTQQSPEVLPCQPQHYHCYRQSSQAQQPPEKNIVYQRVRTYSGPMNKVVQTLDPVGSGEVLSPLKTASSYQSLVWSDHSQELHSPTLKISTCVPGTLHITPNTEQELHSPTVKVTTYPQTTIRRYIVQSPEQEPLSPFLRGGHFFPGNNVIYEKTIRKVEKLNMDQESYPQIQCNHHIVQQPQIIHSPHCEQSHSSQKIQTITGSDSVSTNTGIELCHGGSNHTHEQVIIQDDSPEKLDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKRDFESIDESEDIESLIPKGLSEFTKQQIRYILQMRDMSAKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRADNRQQQQGCQDSTSKCQALEEHNLSLRHTLSDVEYRLKELEYCKRNLEQENKNLRIQVSETCTGPMLQAKMDEIGNHYMEMVKNLRMEKDREICKLRTQLNQYQKDVSRREGSCNDFQFKIHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTKTIVIEKTEDKWTCP", "length": 590 }, "evidence": [ { "id": "A0A8V0Z5M6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5M6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K4L4-1", "protein_name": "Protein POF1B", "gene_name": "Pof1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHYYHQPSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQSLVWSDHSQELYSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPEQEPLSPFLRGSQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNIGHELCHGGPSQIHEQVIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFESTDTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQMKEYEELLASVRANNRQQQQGLQDSSAKCQSLEENNLSLRHTLSDLEYRLKELEYCKRNLEQENKNLRIQVSETCTGPTLQAKMDEIGNHYMEMVKNLRLDKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSCGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "A0A8V0Z5M6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5M6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVV4-2", "protein_name": "Protein POF1B", "gene_name": "POF1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP", "length": 589 }, "evidence": [ { "id": "A0A8V0Z5M6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5M6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M6" }, { "id": "PF24617", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POF1B helix-loop-helix", "eco_id": "ECO_0000259", "start_pos": 260, "end_pos": 340, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 497, "end_pos": 499 }, { "start_pos": 571, "end_pos": 573 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6Q7-1", "uniprot_ac": "A0A8V0Z6Q7", "uniprot_id": "A0A8V0Z6Q7_CHICK", "mass": { "chemical_mass": 158374.0, "monoisotopic_mass": 158374.0 }, "refseq": { "ac": "XP_015141543", "name": "rab11 family-interacting protein 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141543" }, "gene_names": [ { "name": "RAB11FIP5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ] }, { "name": "RAB11FIP5", "type": "synonym", "evidence": [ { "id": "XP_015141543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141543" } ] } ], "protein_names": [ { "name": "RAB11 family interacting protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7/entry#names_and_taxonomy" } ] }, { "name": "rab11 family-interacting protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015141543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141543" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141543" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB11FIP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7", "locus": { "chromosome": "4", "start_pos": 89357182, "end_pos": 89330773, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018302", "url": "https://www.ensembl.org/id/ENSGALG00010018302" } ] } } ], "crossref": [ { "id": "422952", "url": "https://www.ncbi.nlm.nih.gov/gene/422952", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422952", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422952", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YZ06", "url": "https://www.orthodb.org/?gene=A0A8V0YZ06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Q7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCM1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLRAAALPADGPPAWLPTHVQVTVVRARGLRCKGGGGGGKAGSSDAYTIIQLGREKYCTSVAEKSGGCPEWKEECAFELPPTEPGAEAALLLTVMHRALVGMDRFLGMARVPLRAAGLQGRAAEERWHKLHSKPGKKEKERGEIQVSIQFTRNNLTASMFDLSMKDKPRSPFGKLKDKMKGKKKYDLESASAIIPSSMGALDMEDDYDVGGKKSKVKGFFLKNKLRKSSLTQSNTSLGSDSTISSASLGMATGGPEVTRSPSRHSSLSTERSVKDFLPSPKLTHKRAFSDDVSQVSPVLEPKAIHSLKPKTDPVSRSSLCINGSHVYSDEPTPRSPVPTPQGSAPLPVPRRPEEGFGFIPIHTDPHEVPWGAGSLERTQQREELRFIPSPPSLVLQEELKVSTKAVTLSNHLGRARMEENSRLENKPTQVATPMVFSAEVTKEKQPEEMRKEEKKTKGGLFHKSDAGSRGQGEKTGASHGPAAVGDDRSKAGGWFGSKEPKDSPQKPSLEVSPQVETSSDAPSHFPPRSPAQFPAAAVAHLARMLSPNLPPATRDSQPGCLSPTNPFLNSLQSNPFFEDLLADQVLNSPSPTHFFSSFPSEPHASTEVAESLCSSEDCSPSASLRLKDPERESPAKSVGVPVPETTPPSHADPPPPPDEEPAASPPPLSEWDETFDAFATSRLRPDPKKEDFFASVAAEGMAFIDDPDAASPTERSAEPDPEEGTKGFEKAEPQISSEMPPALLSWTNFSGLDVGANLVSTTQEATVIEDVLSPVSAGSAARRRKSSTPMVWAASLSSGNPGEKEASTLLSADNCAGEERDSNEEETSSVGENGWMTIATETSPDPSESTQSIGQGSTFGQRSFHSEGTFETKSTPHVLPRSTFSSESTAETIPGSNVAAVPPRVLQDMAVGRFPAASDTGKELQDDGGEMFDIRSSVYRLQASMRLEAGEGRVKMGSDAVLAPWAGVRGKEEVMPPPKPPRWFAAACGRGDDEDNASDTTARQRGGEEQQEGEEGLEQPRSHPSGDTTVPAPRTVVHEDAADVEAGGDTSLGEEPPEMNGTDAAEHFETCPSRFSVDELTLSGAAGSWSQPALSPVSQLSLSAEPSVAPEQEPCPAELGVSAPDLSPRPDSGLPETFWTALEEQEALGRPHRLALEQDQGEGPAVGCPHQAEQGQLSAGIDFKKVEFWKPDRTEERSEQDAVSPGNPFALAVSPIAPTNPFVEKPADALPIQAVLPERFAQGFSSPQLHGEALQQGFQPTNPRRDPLGNPSLHDSQPLAFSTPFPVAVTNPEQFDFPSPAATSRAAAQPCPLPQSGDTQASALVVLPRETQPAEKPFFQQTTSPHPVKPISAAVQEVSSEKKQQNKSSLTTALSNSLEKLKTVTTGSVQPVAPSSHLEKTDPKKDPTALDQSAKYYHLTHDELIQLLLQREKELSKKEEHIQELEDYIDQLLVRIMEQSPTLLQIPLGEAKTK", "length": 1476, "header": "tr|A0A8V0Z6Q7-1|A0A8V0Z6Q7_CHICK Isoform 1 of RAB11 family interacting protein 5 OS=Gallus gallus OX=9031 GN=RAB11FIP5 PE=1 SV=1 CANONICAL=A0A8V0Z6Q7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7/entry#A0A8V0YZ06-1", "sequence": { "sequence": "MALLRAAALPADGPPAWLPTHVQVTVVRARGLRCKGGGGGGKAGSSDAYTIIQLGREKYCTSVAEKSGGCPEWKEECAFELPPTEPGAEAALLLTVMHRALVGMDRFLGMARVPLRAAGLQGRAAEERWHKLHSKPGKKEKERGEIQVSIQFTRNNLTASMFDLSMKDKPRSPFGKLKDKMKGKKKYDLESASAIIPSSMGALDMEDDYDVGGKKSKVKGFFLKNKLRKSSLTQSNTSLGSDSTISSASLGMATGGPEVTRSPSRHSSLSTERSVKDFLPSPKLTHKRAFSDDVSQVSPVLEPKAIHSLKPKTDPVSRSSLCINGSHVYSDEPTPRSPVPTPQGSAPLPVPRRPEEGFGFIPIHTDPHEVPWGAGSLERTQQREELRFIPSPPSLVLQEELKVSTKAVTLSNHLGRARMEENSRLENKPTQVATPMVFSAEVTKEKQPEEMRKEEKKTKGGLFHKSDAGSRGQGEKTGASHGPAAVGDDRSKAGGWFGSKEPKDSPQKPSFPSEPHASTEVAESLCSSEDCSPSASLRLKDPERESPAKSVGVPVPETTPPSHADPPPPPDEEPAASPPPLSEWDETFDAFATSRLRPDPKKEDFFASVAAEGMAFIDDPDAASPTERSAEPDPEEGTKGFEKAEPQISSEMPPALLSWTNFSGLDVGANLVSTTQEATVIEDVLSPVSAGSAARRRKSSTPMVWAASLSSGNPGEKEASTLLSADNCAGEERDSNEEETSSVGENGWMTIATETSPDPSESTQSIGQGSTFGQRSFHSEGTFETKSTPHVLPRSTFSSESTAETIPGSNVAAVPPRVLQDMAVGRFPAASDTGKELQDDGGEMFDIRSSVYRLQASMRLEAGEGRVKMGSDAVLAPWAGVRGKEEVMPPPKPPRWFAAACGRGDDEDNASDTTARQRGGEEQQEGEEGLEQPRSHPSGDTTVPAPRTVVHEDAADVEAGGDTSLGEEPPEMNGTDAAEHFETCPSRFSVDELTLSGAAGSWSQPALSPVSQLSLSAEPSVAPEQEPCPAELGVSAPDLSPRPDSGLPETFWTALEEQEALGRPHSRAAAQPCPLPQSGDTQASALVVLPRETQPAEKPFFQQTTSPHPVKPISAAVQEVSSEKKQQNKSSLTTALSNSLEKLKTVTTGSVQPVAPSSHLEKTDPKKVKDPTALDQSAKYYHLTHDELIQLLLQREKELSKKEEHIQELEDYIDQLLVRIMEQSPTLLQIPLGEAKTK", "length": 1238, "header": "tr|A0A8V0YZ06-1|A0A8V0Z6Q7_CHICK Computationally mapped isoform of RAB11 family interacting protein 5 OS=Gallus gallus OX=9031 GN=RAB11FIP5 PE=1 SV=1 CANONICAL=A0A8V0Z6Q7-1" }, "locus": { "chromosome": "4", "start_pos": 89353552, "end_pos": 89330904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044157.1", "url": "https://www.ensembl.org/id/ENSGALT00010044157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026257.1", "url": "https://www.ensembl.org/id/ENSGALP00010026257.1" } ] } }, { "isoform_ac": "A0A8V0Z6Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7/entry#A0A8V0Z6Q7-1", "sequence": { "sequence": "MALLRAAALPADGPPAWLPTHVQVTVVRARGLRCKGGGGGGKAGSSDAYTIIQLGREKYCTSVAEKSGGCPEWKEECAFELPPTEPGAEAALLLTVMHRALVGMDRFLGMARVPLRAAGLQGRAAEERWHKLHSKPGKKEKERGEIQVSIQFTRNNLTASMFDLSMKDKPRSPFGKLKDKMKGKKKYDLESASAIIPSSMGALDMEDDYDVGGKKSKVKGFFLKNKLRKSSLTQSNTSLGSDSTISSASLGMATGGPEVTRSPSRHSSLSTERSVKDFLPSPKLTHKRAFSDDVSQVSPVLEPKAIHSLKPKTDPVSRSSLCINGSHVYSDEPTPRSPVPTPQGSAPLPVPRRPEEGFGFIPIHTDPHEVPWGAGSLERTQQREELRFIPSPPSLVLQEELKVSTKAVTLSNHLGRARMEENSRLENKPTQVATPMVFSAEVTKEKQPEEMRKEEKKTKGGLFHKSDAGSRGQGEKTGASHGPAAVGDDRSKAGGWFGSKEPKDSPQKPSLEVSPQVETSSDAPSHFPPRSPAQFPAAAVAHLARMLSPNLPPATRDSQPGCLSPTNPFLNSLQSNPFFEDLLADQVLNSPSPTHFFSSFPSEPHASTEVAESLCSSEDCSPSASLRLKDPERESPAKSVGVPVPETTPPSHADPPPPPDEEPAASPPPLSEWDETFDAFATSRLRPDPKKEDFFASVAAEGMAFIDDPDAASPTERSAEPDPEEGTKGFEKAEPQISSEMPPALLSWTNFSGLDVGANLVSTTQEATVIEDVLSPVSAGSAARRRKSSTPMVWAASLSSGNPGEKEASTLLSADNCAGEERDSNEEETSSVGENGWMTIATETSPDPSESTQSIGQGSTFGQRSFHSEGTFETKSTPHVLPRSTFSSESTAETIPGSNVAAVPPRVLQDMAVGRFPAASDTGKELQDDGGEMFDIRSSVYRLQASMRLEAGEGRVKMGSDAVLAPWAGVRGKEEVMPPPKPPRWFAAACGRGDDEDNASDTTARQRGGEEQQEGEEGLEQPRSHPSGDTTVPAPRTVVHEDAADVEAGGDTSLGEEPPEMNGTDAAEHFETCPSRFSVDELTLSGAAGSWSQPALSPVSQLSLSAEPSVAPEQEPCPAELGVSAPDLSPRPDSGLPETFWTALEEQEALGRPHRLALEQDQGEGPAVGCPHQAEQGQLSAGIDFKKVEFWKPDRTEERSEQDAVSPGNPFALAVSPIAPTNPFVEKPADALPIQAVLPERFAQGFSSPQLHGEALQQGFQPTNPRRDPLGNPSLHDSQPLAFSTPFPVAVTNPEQFDFPSPAATSRAAAQPCPLPQSGDTQASALVVLPRETQPAEKPFFQQTTSPHPVKPISAAVQEVSSEKKQQNKSSLTTALSNSLEKLKTVTTGSVQPVAPSSHLEKTDPKKDPTALDQSAKYYHLTHDELIQLLLQREKELSKKEEHIQELEDYIDQLLVRIMEQSPTLLQIPLGEAKTK", "length": 1476, "header": "tr|A0A8V0Z6Q7-1|A0A8V0Z6Q7_CHICK Isoform 1 of RAB11 family interacting protein 5 OS=Gallus gallus OX=9031 GN=RAB11FIP5 PE=1 SV=1 CANONICAL=A0A8V0Z6Q7-1" }, "locus": { "chromosome": "4", "start_pos": 89353552, "end_pos": 89330904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044162.1", "url": "https://www.ensembl.org/id/ENSGALT00010044162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026260.1", "url": "https://www.ensembl.org/id/ENSGALP00010026260.1" } ] } }, { "isoform_ac": "A0A8V0ZCM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7/entry#A0A8V0ZCM1-1", "sequence": { "sequence": "MALLRAAALPADGPPAWLPTHVQVTVVRARGLRCKGGGGGGKAGSSDAYTIIQLGREKYCTSVAEKSGGCPEWKEECAFELPPTEPGAEAALLLTVMHRALVGMDRFLGMARVPLRAAGLQGRAAEERWHKLHSKPGKKEKERGEIQVSIQFTRNNLTASMFDLSMKDKPRSPFGKLKDKMKGKKKYDLESASAIIPSSMGALDMEDDYDVGGKKSKVKGFFLKNKLRKSSLTQSNTSLGSDSTISSASLGMATGGPEVTRSPSRHSSLSTERSVKDFLPSPKLTHKRAFSDDVSQVSPVLEPKAIHSLKPKTDPVSRSSLCINGSHVYSDEPTPRSPVPTPQGSAPLPVPRRPEEGFGFIPIHTDPHEVPWGAGSLERTQQREELRFIPSPPSLVLQEELKVSTKAVTLSNHLGRARMEENSRLENKPTQVATPMVFSAEVTKEKQPEEMRKEEKKTKGGLFHKSDAGSRGQGEKTGASHGPAAVGDDRSKAGGWFGSKEPKDSPQKPSPHPVKPISAAVQEVSSEKKQQNKSSLTTALSNSLEKLKTVTTGSVQPVAPSSHLEKTDPKKVKDPTALDQSAKYYHLTHDELIQLLLQREKELSKKEEHIQELEDYIDQLLVRIMEQSPTLLQIPLGEAKTK", "length": 642, "header": "tr|A0A8V0ZCM1-1|A0A8V0ZCM1_CHICK Computationally mapped isoform of RAB11 family interacting protein 5 OS=Gallus gallus OX=9031 GN=RAB11FIP5 PE=1 SV=1 CANONICAL=A0A8V0Z6Q7-1" }, "locus": { "chromosome": "4", "start_pos": 89353552, "end_pos": 89330904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044165.1", "url": "https://www.ensembl.org/id/ENSGALT00010044165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026263.1", "url": "https://www.ensembl.org/id/ENSGALP00010026263.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422952", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422952", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1368, "end_pos": 1370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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{ "uniprot_canonical_ac": "A0A8V0Z5S9-1", "uniprot_ac": "A0A8V0Z5S9", "uniprot_id": "A0A8V0Z5S9_CHICK", "mass": { "chemical_mass": 66238.0, "monoisotopic_mass": 66238.0 }, "refseq": {}, "gene_names": [ { "name": "MYEF2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ] } ], "protein_names": [ { "name": "Myelin expression factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9", "locus": { "chromosome": "10", "start_pos": 10070904, "end_pos": 10094974, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018313", "url": "https://www.ensembl.org/id/ENSGALG00010018313" } ] } } ], "crossref": [ { "id": "A0A8V0Z5S9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032546", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415432", "url": "https://www.ncbi.nlm.nih.gov/gene/415432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ30", "url": "https://www.orthodb.org/?gene=A0A8V0YZ30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ35", "url": "https://www.orthodb.org/?gene=A0A8V0YZ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z591", "url": "https://www.orthodb.org/?gene=A0A8V0Z591", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2UAH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UAH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z591", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z591", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z591-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z591-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRVSAVGNNLVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGEMFRGGMGGNMDRDFARSEMALNRGFGDSFGRMGGAMIGVFAGGMGAPRMGPVGSGMSGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 621, "header": "tr|A0A8V0Z5S9-1|A0A8V0Z5S9_CHICK Isoform 1 of Myelin expression factor 2 OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UAH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A3Q2UAH4-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRVSGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGEMFRGGMGGNMDRDFARSEMALNRGFGDSFGRMGGAMIGVFAGGMGAPRMGPVGSGMSGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 616, "header": "tr|A0A3Q2UAH4-1|A0A8V0Z5S9_CHICK Computationally mapped isoform of Myelin expression factor 2 OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044208.1", "url": "https://www.ensembl.org/id/ENSGALT00010044208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026293.1", "url": "https://www.ensembl.org/id/ENSGALP00010026293.1" } ] } }, { "isoform_ac": "A0A8V0YZ30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A8V0YZ30-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGGGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 559, "header": "tr|A0A8V0YZ30-1|A0A8V0Z5S9_CHICK Computationally mapped isoform of Myelin expression factor 2 OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044184.1", "url": "https://www.ensembl.org/id/ENSGALT00010044184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026278.1", "url": "https://www.ensembl.org/id/ENSGALP00010026278.1" } ] } }, { "isoform_ac": "A0A8V0YZ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A8V0YZ35-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGEMFRGGMGGNMDRDFARSEMALNRGFGDSFGRMGGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 592, "header": "tr|A0A8V0YZ35-1|A0A8V0Z5S9_CHICK Computationally mapped isoform of Myelin expression factor 2 OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044192.1", "url": "https://www.ensembl.org/id/ENSGALT00010044192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026283.1", "url": "https://www.ensembl.org/id/ENSGALP00010026283.1" } ] } }, { "isoform_ac": "A0A8V0Z591-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A8V0Z591-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGLPGFRGMEGMPNMGGFGVSRMGEMFRGGMGGNMDRDFARSEMALNRGFGDSFGRMGGAMIGVFAGGMGAPRMGPVGSGMSGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 577, "header": "tr|A0A8V0Z591-1|A0A8V0Z591_CHICK Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044204.1", "url": "https://www.ensembl.org/id/ENSGALT00010044204.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026290.1", "url": "https://www.ensembl.org/id/ENSGALP00010026290.1" } ] } }, { "isoform_ac": "A0A8V0Z5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A8V0Z5S9-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRVSAVGNNLVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGEMFRGGMGGNMDRDFARSEMALNRGFGDSFGRMGGAMIGVFAGGMGAPRMGPVGSGMSGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 621, "header": "tr|A0A8V0Z5S9-1|A0A8V0Z5S9_CHICK Isoform 1 of Myelin expression factor 2 OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044197.1", "url": "https://www.ensembl.org/id/ENSGALT00010044197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026287.1", "url": "https://www.ensembl.org/id/ENSGALP00010026287.1" } ] } }, { "isoform_ac": "A0A8V0ZCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9/entry#A0A8V0ZCM9-1", "sequence": { "sequence": "MAENDKPEAAAAVLQRGADEAAIAGQPPPQQQQPPPQQQPQQQPPQREEAAAATESGGGSANGVKMDNDETAKEEKAPVKEKHAKPKAIPSLGNKNRFHPYSKEKSTGSAEKKAINRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPEGEHARRALQRGGGQFAGGHGPDVAPGLMNLPPSIVNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDFRVVDSKASQLPRGLGGIGMGLGPGGQPISATQLSMGGGMGNVGPGGMGIDGPGFGGMNRMGGGLPGFRGMEGMPNMGGFGVSRMGGGAMIGVFAGGMGAPRMGPVGSGMSGGMGGMNSMPGGMGMDRMSSGFDRMGPAMGGGLDRNIDIDRGFVPGPMGGAMKERLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA", "length": 583, "header": "tr|A0A8V0ZCM9-1|A0A8V0ZCM9_CHICK Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=MYEF2 PE=1 SV=1 CANONICAL=A0A8V0Z5S9-1" }, "locus": { "chromosome": "10", "start_pos": 10094881, "end_pos": 10077707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044179.1", "url": "https://www.ensembl.org/id/ENSGALT00010044179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026274.1", "url": "https://www.ensembl.org/id/ENSGALP00010026274.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 201, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6E5-1", "uniprot_ac": "A0A8V0Z6E5", "uniprot_id": "A0A8V0Z6E5_CHICK", "mass": { "chemical_mass": 19329.0, "monoisotopic_mass": 19329.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM159", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5" } ] } ], "protein_names": [ { "name": "Lipid droplet assembly factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM159", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6E5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "427005", "url": "https://www.ncbi.nlm.nih.gov/gene/427005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427005", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNYWFPP", "url": "https://omabrowser.org/oma/group/VNYWFPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ42", "url": "https://www.orthodb.org/?gene=A0A8V0YZ42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZH9", "url": "https://www.orthodb.org/?gene=A0A8V0YZH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6E5", "url": "https://www.orthodb.org/?gene=A0A8V0Z6E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14275:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14275:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YZ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKELQELQKQWHFIVQSIHSNSNVVAFMNSRLGLYLDDHPFVALSLLMFVAVSTIPVAFFLIFVVTTVIMACVGVIVMEGAKRGSKKLMEVRHRRVCLSWTSRTTNERTNKWDSVHLLCTHSAVQVCPLQCNCLLVEHPTSVHSVWELKEPTCIVCCHCNTNGGSTHCDTA", "length": 172, "header": "tr|A0A8V0Z6E5-1|A0A8V0Z6E5_CHICK Isoform 1 of Lipid droplet assembly factor 1 OS=Gallus gallus OX=9031 GN=TMEM159 PE=3 SV=1 CANONICAL=A0A8V0Z6E5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5/entry#A0A8V0YZ42-1", "sequence": { "sequence": "MSKELQELQKQWHFIVQSIHSNSNVVAFMNSRLGLYLDDHPFVALSLLMFVAVSTIPVAFFLIFVVTTVIMACVGVIVMEGVVISIGGIALLCVLCGLGALSLGVSGVLSVCYIILSALVNYWCASRSQARKQEVNGSSPQKSLSVMDFSDDKRKNK", "length": 157, "header": "tr|A0A8V0YZ42-1|A0A8V0Z6E5_CHICK Computationally mapped isoform of Lipid droplet assembly factor 1 OS=Gallus gallus OX=9031 GN=TMEM159 PE=3 SV=1 CANONICAL=A0A8V0Z6E5-1" }, "locus": { "chromosome": "14", "start_pos": 15139763, "end_pos": 15136981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041125.1", "url": "https://www.ensembl.org/id/ENSGALT00010041125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024063.1", "url": "https://www.ensembl.org/id/ENSGALP00010024063.1" } ] } }, { "isoform_ac": "A0A8V0YZH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5/entry#A0A8V0YZH9-1", "sequence": { "sequence": "MKAEALFFPPQVVAFMNSRLGLYLDDHPFVALSLLMFVAVSTIPVAFFLIFVVTTVIMACVGVIVMEGVVISIGGIALLCVLCGLGALSLGVSGVLSVCYIILSALVNYWCASRSQARKQEVNGSSPQKSLSVMDFSDDKRKNK", "length": 144, "header": "tr|A0A8V0YZH9-1|A0A8V0Z6E5_CHICK Computationally mapped isoform of Lipid droplet assembly factor 1 OS=Gallus gallus OX=9031 GN=TMEM159 PE=3 SV=1 CANONICAL=A0A8V0Z6E5-1" }, "locus": { "chromosome": "14", "start_pos": 15139763, "end_pos": 15137537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041128.1", "url": "https://www.ensembl.org/id/ENSGALT00010041128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024065.1", "url": "https://www.ensembl.org/id/ENSGALP00010024065.1" } ] } }, { "isoform_ac": "A0A8V0Z6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5/entry#A0A8V0Z6E5-1", "sequence": { "sequence": "MSKELQELQKQWHFIVQSIHSNSNVVAFMNSRLGLYLDDHPFVALSLLMFVAVSTIPVAFFLIFVVTTVIMACVGVIVMEGAKRGSKKLMEVRHRRVCLSWTSRTTNERTNKWDSVHLLCTHSAVQVCPLQCNCLLVEHPTSVHSVWELKEPTCIVCCHCNTNGGSTHCDTA", "length": 172, "header": "tr|A0A8V0Z6E5-1|A0A8V0Z6E5_CHICK Isoform 1 of Lipid droplet assembly factor 1 OS=Gallus gallus OX=9031 GN=TMEM159 PE=3 SV=1 CANONICAL=A0A8V0Z6E5-1" }, "locus": { "chromosome": "14", "start_pos": 15139947, "end_pos": 15136981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041130.1", "url": "https://www.ensembl.org/id/ENSGALT00010041130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024067.1", "url": "https://www.ensembl.org/id/ENSGALP00010024067.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427005", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9U255-1", "protein_name": "Lipid droplet assembly factor 1", "gene_name": "LDAF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKEEPPSTSKDLQELQRKLSLLIASVQSNSKVVSFMKSPVGQYLDRHPFLTLTLLVFVALSAVPVGFFLLLVVLTSLAAFVGVILLEGLVISVGGLALLCVLCGLGFVSLVMSGTIMVSYMVISSLINYWFSLRLLPQHNSSGDCPLAVKSAHIEGLYQE", "length": 161 }, "evidence": [ { "id": "A0A8V0Z6E5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UK00-1", "protein_name": "Lipid droplet assembly factor 1", "gene_name": "Ldaf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEEPSSVSRDLQELQRKLGLLLESFQNNSKVVAFMKSPVGRFLDRHPFLVLTVLMFVTMSAIPVGFFLLIVVLTSLGALMGAILLEGLVISVCGLSLLCILCGLGFVSLALSGITMMSYVVVSCLMSYWFSPSRPPTQQHANIDSQLAMKFTESEKLGL", "length": 161 }, "evidence": [ { "id": "A0A8V0Z6E5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q922Z1-1", "protein_name": "Lipid droplet assembly factor 1", "gene_name": "Ldaf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKEEPPSVSRDLQELQRKLGLLLESFLNNSKVVAFMKSPVGRFLDRHPFVTLTVLMFVTMSAIPVGFFLLIVVLTSLGALMGAILLEGLVISVCGLSLLCVLCGLGFLSLALSGIAMMSYVVVSCLMSYWFSPSRPLTQQNANVDCQLAMKFTESERLIF", "length": 161 }, "evidence": [ { "id": "A0A8V0Z6E5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96B96-1", "protein_name": "Lipid droplet assembly factor 1", "gene_name": "LDAF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKEEPQSISRDLQELQKKLSLLIDSFQNNSKVVAFMKSPVGQYLDSHPFLAFTLLVFIVMSAVPVGFFLLIVVLTTLAALLGVIILEGLVISVGGFSLLCILCGLGFVSLAMSGMMIASYVVVSSLISCWFSPRPLTQQNTSCDFLPAMKSAEFEGLYQE", "length": 161 }, "evidence": [ { "id": "A0A8V0Z6E5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z799-1", "uniprot_ac": "A0A8V0Z799", "uniprot_id": "A0A8V0Z799_CHICK", "mass": { "chemical_mass": 126086.0, "monoisotopic_mass": 126086.0 }, "refseq": {}, "gene_names": [ { "name": "CKAP2L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ] } ], "protein_names": [ { "name": "Cytoskeleton associated protein 2 like", "type": "synonym", "evidence": [ { "id": "A0A8V0Z799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CKAP2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z799", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z799", "database": "AlphaFoldDB", "categories": [] }, { "id": "426694", "url": "https://www.ncbi.nlm.nih.gov/gene/426694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426694", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVMEGAQ", "url": "https://omabrowser.org/oma/group/NVMEGAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZM2", "url": "https://www.orthodb.org/?gene=A0A8V0YZM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z795", "url": "https://www.orthodb.org/?gene=A0A8V0Z795", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z799", "url": "https://www.orthodb.org/?gene=A0A8V0Z799", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47078:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47078:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z795", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z795", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z795-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z795-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z799-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRVQPLLPRHAVPRGIAALGPVGLSHASFMFHYRPVAFNLYIYIFYRNYDGFISSPLVGVEVFIVTGEIKASLWTRVSVCASGDRSGRFRPEEQRSHSRAGPVPHAQAASCSPPPLWVPGGKDRGLLRPSGPPQSPPRHSSEPSITPQELSPIPSQSPPSEPPHSPSETLETSRIPLRTLPEPSRSPQPPPRLPPAPPTRSSPPHPLSYTNECDWPTHTSGPTRGSVVPAPSARFAQSQLPVSAPPPSAPSLPSSLRRSPLDGLKEAAANGRGAVVGAVVWGGLRTWRLRKVREGSGAPDRDPGPNLGPGSGTGGAGSLGRLRIRVLVERNPPAGLRALWGRGVATKCGLRGGVGGCGGGSGMWCVGRGSGWGRGWEGGGLTALCRSRRMESECLRDATAIGRGEWRLDGTDSLGELWVPHCWWCPGAVGSASPVLQACKALQRAVGSTPCVPGVGGLSGSSAVLQEEPGDNARSRSSEGCVCTAFSYRFFAEERRRQLQEYLEAKGKLKCPSTKAYLKDRTNHLDPLLKPVSKPERLDRNKKGAVQNVAKGTWKDGKLAAKPAQPAGCAALQQSSRASQRVAVVQPRQLGKDTKLPAGLVPSTNPSAQRRGRLPTSASRLLNPGGLEETGSGQPAAGAPCLLNKGLQDRLGCGKENLPARAATNPVPSNTFQSNGNNLGKKRALAHGQGSGAVSRTVRDPKDRINSCQAKEVLIQEKFRKPLPGSKSASQKPSGTTRPLQSPQLLANSTHLLHKKPVVKQEKSNAARGPVGKLGTSLMGTLKHSNRAPAKPPASSRPLGTASGPTRTPSLKLCTAVQWQRPTVREGADRKDVKTAPSRHTATSRAAVPKKQSLPSTYSSRTQGNRGEFGSRREMHKPELPQTHGVRAGRVPKSPTPEDRRRQLEQWLASKGKCYKRPPMTLPPKKPMKQKEKPPLRSAVQEEEKPEKPEQLYQARINALLSECLKLIEEGVPSEELSAILCHEPSVEKCAKFWICKAKLLARSGPFDATGLYEAAVCAGAEPLQELREVVLDILKTAEQPAEGEKPEQPVLWEPTTPCPGERQHTAVTPCRTESALSSLPVSSIKLQVTSVPRTREMPEGQELKFLTPVRRSLRIERVGSRYPEMLRDHDPVVSSLSEILDDDEETQFFFRMNKALPEVAEMEVLRL", "length": 1169, "header": "tr|A0A8V0Z799-1|A0A8V0Z799_CHICK Isoform 1 of Cytoskeleton associated protein 2 like OS=Gallus gallus OX=9031 GN=CKAP2L PE=3 SV=1 CANONICAL=A0A8V0Z799-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799/entry#A0A8V0YZM2-1", "sequence": { "sequence": "MRLADAHFRPHPGLRCTRPIRSLRPITAPRLRPASFCPLPPLLPSAFSIGRFERGCGQWARGGGWGGGLGRIEDMAAAQEERRRQLQEYLEAKGKLKCPSTKAYLKDRTNHLDPLLKPVSKPERLDRNKKGAVQNVAKGTWKDGKLAAKPAQPAGCAALQQSSRASQRVAVVQPRQLGKDTKLPAGLVPSTNPSAQRRGRLPTSASRLLNPGGLEETGSGQPAAGAPCLLNKGLQDRLGCGKENLPARAATNPVPSNTFQSNGNNLGKKRALAHGQGSGAVSRTVRDPKDRINSCQAKEVLIQEKFRKPLPGSKSASQKPSGTTRPLQSPQLLANSTHLLHKKPVVKQEKSNAARGPVGKLGTSLMGTLKHSNRAPAKPPASSRPLGTASGPTRTPSLKLCTAVQWQRPTVREGADRKDVKTAPSRHTATSRAAVPKKQSLPSTYSSRTQGNRGEFGSRREMHKPELPQTHGVRAGRVPKSPTPEDRRRQLEQWLASKGKCYKRPPMTLPPKKPMKQKEKPPLRSAVQEEEKPEKPEQLYQARINALLSECLKLIEEGVPSEELSAILCHEPSVEKCAKFWICKAKLLARSGPFDATGLYEAAVCAGAEPLQELREVVLDILKTAEQPAEGEKPEQPVLWEPTTPCPGERQHTAVTPCRTESALSSLPVSSIKLQVTSVPRTREMPEGQELKFLTPVRRSLRIERVGSRYPEMLRDHDPVVSSLSEILDDDEETQFFFRMNKALPEVAEMEVLRL", "length": 755, "header": "tr|A0A8V0YZM2-1|A0A8V0Z799_CHICK Computationally mapped isoform of Cytoskeleton associated protein 2 like OS=Gallus gallus OX=9031 GN=CKAP2L PE=3 SV=1 CANONICAL=A0A8V0Z799-1" }, "locus": { "chromosome": "22", "start_pos": 4456950, "end_pos": 4450787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044453.1", "url": "https://www.ensembl.org/id/ENSGALT00010044453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026456.1", "url": "https://www.ensembl.org/id/ENSGALP00010026456.1" } ] } }, { "isoform_ac": "A0A8V0Z795-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799/entry#A0A8V0Z795-1", "sequence": { "sequence": "MPQYQLDRNKKGAVQNVAKGTWKDGKLAAKPAQPAGCAALQQSSRASQRVAVVQPRQLGKDTKLPAGLVPSTNPSAQRRGRLPTSASRLLNPGGLEETGSGQPAAGAPCLLNKGLQDRLGCGKENLPARAATNPVPSNTFQSNGNNLGKKRALAHGQGSGAVSRTVRDPKDRINSCQAKEVLIQEKFRKPLPGSKSASQKPSGTTRPLQSPQLLANSTHLLHKKPVVKQEKSNAARGPVGKLGTSLMGTLKHSNRAPAKPPASSRPLGTASGPTRTPSLKLCTAVQWQRPTVREGADRKDVKTAPSRHTATSRAAVPKKQSLPSTYSSRTQGNRGEFGSRREMHKPELPQTHGVRAGRVPKSPTPEDRRRQLEQWLASKGKCYKRPPMTLPPKKPMKQKEKPPLRSAVQEEEKPEKPEQLYQARINALLSECLKLIEEGVPSEELSAILCHEPSVEKCAKFWICKAKLLARSGPFDATGLYEAAVCAGAEPLQELREVVLDILKTAEQPAEGEKPEQPVLWEPTTPCPGERQHTAVTPCRTESALSSLPVSSIKLQVTSVPRTREMPEGQELKFLTPVRRSLRIERVGSRYPEMLRDHDPVVSSLSEILDDDEETQFFFRMNKALPEVAEMEVLRL", "length": 636, "header": "tr|A0A8V0Z795-1|A0A8V0Z795_CHICK Computationally mapped isoform of Cytoskeleton associated protein 2 like OS=Gallus gallus OX=9031 GN=CKAP2L PE=3 SV=1 CANONICAL=A0A8V0Z799-1" }, "locus": { "chromosome": "22", "start_pos": 4456056, "end_pos": 4450787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044447.1", "url": "https://www.ensembl.org/id/ENSGALT00010044447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026454.1", "url": "https://www.ensembl.org/id/ENSGALP00010026454.1" } ] } }, { "isoform_ac": "A0A8V0Z799-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799/entry#A0A8V0Z799-1", "sequence": { "sequence": "MYRVQPLLPRHAVPRGIAALGPVGLSHASFMFHYRPVAFNLYIYIFYRNYDGFISSPLVGVEVFIVTGEIKASLWTRVSVCASGDRSGRFRPEEQRSHSRAGPVPHAQAASCSPPPLWVPGGKDRGLLRPSGPPQSPPRHSSEPSITPQELSPIPSQSPPSEPPHSPSETLETSRIPLRTLPEPSRSPQPPPRLPPAPPTRSSPPHPLSYTNECDWPTHTSGPTRGSVVPAPSARFAQSQLPVSAPPPSAPSLPSSLRRSPLDGLKEAAANGRGAVVGAVVWGGLRTWRLRKVREGSGAPDRDPGPNLGPGSGTGGAGSLGRLRIRVLVERNPPAGLRALWGRGVATKCGLRGGVGGCGGGSGMWCVGRGSGWGRGWEGGGLTALCRSRRMESECLRDATAIGRGEWRLDGTDSLGELWVPHCWWCPGAVGSASPVLQACKALQRAVGSTPCVPGVGGLSGSSAVLQEEPGDNARSRSSEGCVCTAFSYRFFAEERRRQLQEYLEAKGKLKCPSTKAYLKDRTNHLDPLLKPVSKPERLDRNKKGAVQNVAKGTWKDGKLAAKPAQPAGCAALQQSSRASQRVAVVQPRQLGKDTKLPAGLVPSTNPSAQRRGRLPTSASRLLNPGGLEETGSGQPAAGAPCLLNKGLQDRLGCGKENLPARAATNPVPSNTFQSNGNNLGKKRALAHGQGSGAVSRTVRDPKDRINSCQAKEVLIQEKFRKPLPGSKSASQKPSGTTRPLQSPQLLANSTHLLHKKPVVKQEKSNAARGPVGKLGTSLMGTLKHSNRAPAKPPASSRPLGTASGPTRTPSLKLCTAVQWQRPTVREGADRKDVKTAPSRHTATSRAAVPKKQSLPSTYSSRTQGNRGEFGSRREMHKPELPQTHGVRAGRVPKSPTPEDRRRQLEQWLASKGKCYKRPPMTLPPKKPMKQKEKPPLRSAVQEEEKPEKPEQLYQARINALLSECLKLIEEGVPSEELSAILCHEPSVEKCAKFWICKAKLLARSGPFDATGLYEAAVCAGAEPLQELREVVLDILKTAEQPAEGEKPEQPVLWEPTTPCPGERQHTAVTPCRTESALSSLPVSSIKLQVTSVPRTREMPEGQELKFLTPVRRSLRIERVGSRYPEMLRDHDPVVSSLSEILDDDEETQFFFRMNKALPEVAEMEVLRL", "length": 1169, "header": "tr|A0A8V0Z799-1|A0A8V0Z799_CHICK Isoform 1 of Cytoskeleton associated protein 2 like OS=Gallus gallus OX=9031 GN=CKAP2L PE=3 SV=1 CANONICAL=A0A8V0Z799-1" }, "locus": { "chromosome": "22", "start_pos": 4457619, "end_pos": 4450787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044456.1", "url": "https://www.ensembl.org/id/ENSGALT00010044456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026459.1", "url": "https://www.ensembl.org/id/ENSGALP00010026459.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1070, "start_aa": "Thr", "end_pos": 1070, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1070", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 897, "start_aa": "Thr", "end_pos": 897, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr897", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426694", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426694", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z799", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z799" }, { "id": "PF15297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15297" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytoskeleton-associated protein 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 896, "end_pos": 1042, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 224, 897, 1070 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 749, "end_pos": 751 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6B2-1", "uniprot_ac": "A0A8V0Z6B2", "uniprot_id": "A0A8V0Z6B2_CHICK", "mass": { "chemical_mass": 65303.0, "monoisotopic_mass": 65303.0 }, "refseq": { "ac": "XP_001232922", "name": "coiled-coil domain-containing protein 78 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232922" }, "gene_names": [ { "name": "CCDC78", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2" } ] }, { "name": "CCDC78", "type": "synonym", "evidence": [ { "id": "XP_001232922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232922" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 78", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 78 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001232922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001232922.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2", "locus": { "chromosome": "14", "start_pos": 13192384, "end_pos": 13206403, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018403", "url": "https://www.ensembl.org/id/ENSGALG00010018403" } ] } } ], "crossref": [ { "id": "A0A8V0Z6B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "769634", "url": "https://www.ncbi.nlm.nih.gov/gene/769634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769634", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAGTSKK", "url": "https://omabrowser.org/oma/group/WAGTSKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZM7", "url": "https://www.orthodb.org/?gene=A0A8V0YZM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6B2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22106:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22106:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YZM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFGSVADKENANALMEQAQHLANKNVQLQDRNERLYAGFGDVQERMGRLAGSKPDLSPRTIFSEEEKLKISKELVDLQIETNKMKEQYETEKFELKNMILALENRVLELELRSEKVSRERDALRDQLHALETSRKELADEYIILKSNYLALGKELDQEVLKNEELSLELLSLTNARSTESNHHHSHASATEPAAEPDRVRVTLHHPPAQKVKPEVVAAPEHEWQKPGRNLLGNQDHIKEEIEKLKQTYDSQQQKLEEKVIAMGKELQEAKKAVCDPQQKLAEQSAVLLACQSQLQEVEAENSRLQLRLKELSEEYRCRLTQYIRDVAEYMDSKPSTRTGPGKAPAEHADMKRFVDNMLKDIRASYKAREEQLAGAARSYKKRMKSLAKKHENLLIAYSVQREKILSLGSSEMDSGPAELHFAITDPELLTNTTQELNRLRENKAKLEMQLHELQKKRLKETSGFQLSPDQKRDEEGWAEVRKQLQEFTHTTQEDLEKERSQLLTRAIVAEEQVLELQDYIEKHLARYRQEVLRVRKLAGGEEPRAHSAGAADAHSLPRSRRAVSREL", "length": 568, "header": "tr|A0A8V0Z6B2-1|A0A8V0Z6B2_CHICK Isoform 1 of Coiled-coil domain containing 78 OS=Gallus gallus OX=9031 GN=CCDC78 PE=4 SV=1 CANONICAL=A0A8V0Z6B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2/entry#A0A8V0YZM7-1", "sequence": { "sequence": "MDFGSVADKENANALMEQAQHLANKNVQLQDRNERLYAGFGDVQERMGRLAGSKPDLSPRTIFSEEEKLKISKELVDLQIETNKMKEQYETEKFELKNMILALENRVLELELRSEKVSRERDALRDQLHALETSRKELADEYIILKSNYLALGKELDQEVLKNEELSLELLSLTNARSTESNHHHSHASATEPAAEPDRVRVTLHHPPAQKVKLLGNQDHIKEEIEKLKQTYDSQQQKLEEKVIAMGKELQEAKKAVCDPQQKLAEQSAVLLACQSQLQEVEAENSRLQLRLKELSEEYRCRLTQYIRDVAEYMDSKPSTRTGPGKAPAEHADMKRFVDNMLKDIRASYKAREEQLAGAARSYKKRMKSLAKKHENLLIAYSVQREKILSLGSSEMDSGPAELHFAITDPELLTNTTQELNRLRENKAKLEMQLHELQKKRLKETSGFQLSPDQKRDEEGWAEVRKQLQEFTHTTQEDLEKERSQLLTRAIVAEEQVLELQDYIEKHLARYRQEVLRVRKLAGGEEPRAHSAGAADAHSLPRSRRAVSREL", "length": 551, "header": "tr|A0A8V0YZM7-1|A0A8V0Z6B2_CHICK Computationally mapped isoform of Coiled-coil domain containing 78 OS=Gallus gallus OX=9031 GN=CCDC78 PE=4 SV=1 CANONICAL=A0A8V0Z6B2-1" }, "locus": { "chromosome": "14", "start_pos": 13206272, "end_pos": 13192596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044458.1", "url": "https://www.ensembl.org/id/ENSGALT00010044458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026461.1", "url": "https://www.ensembl.org/id/ENSGALP00010026461.1" } ] } }, { "isoform_ac": "A0A8V0Z6B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2/entry#A0A8V0Z6B2-1", "sequence": { "sequence": "MDFGSVADKENANALMEQAQHLANKNVQLQDRNERLYAGFGDVQERMGRLAGSKPDLSPRTIFSEEEKLKISKELVDLQIETNKMKEQYETEKFELKNMILALENRVLELELRSEKVSRERDALRDQLHALETSRKELADEYIILKSNYLALGKELDQEVLKNEELSLELLSLTNARSTESNHHHSHASATEPAAEPDRVRVTLHHPPAQKVKPEVVAAPEHEWQKPGRNLLGNQDHIKEEIEKLKQTYDSQQQKLEEKVIAMGKELQEAKKAVCDPQQKLAEQSAVLLACQSQLQEVEAENSRLQLRLKELSEEYRCRLTQYIRDVAEYMDSKPSTRTGPGKAPAEHADMKRFVDNMLKDIRASYKAREEQLAGAARSYKKRMKSLAKKHENLLIAYSVQREKILSLGSSEMDSGPAELHFAITDPELLTNTTQELNRLRENKAKLEMQLHELQKKRLKETSGFQLSPDQKRDEEGWAEVRKQLQEFTHTTQEDLEKERSQLLTRAIVAEEQVLELQDYIEKHLARYRQEVLRVRKLAGGEEPRAHSAGAADAHSLPRSRRAVSREL", "length": 568, "header": "tr|A0A8V0Z6B2-1|A0A8V0Z6B2_CHICK Isoform 1 of Coiled-coil domain containing 78 OS=Gallus gallus OX=9031 GN=CCDC78 PE=4 SV=1 CANONICAL=A0A8V0Z6B2-1" }, "locus": { "chromosome": "14", "start_pos": 13206272, "end_pos": 13192596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044465.1", "url": "https://www.ensembl.org/id/ENSGALT00010044465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026465.1", "url": "https://www.ensembl.org/id/ENSGALP00010026465.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769634", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABI0NZX6-1", "protein_name": "Coiled-coil domain containing 78", "gene_name": "CCDC78", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEHGAAPVPPPRATENVLPRAEAWLPGVPGGAPAWATNLGTELPSDLELSEEQRLQVGVGLLGAGRREGIPRASQTHPDQPQVCKELVDLQIKNQRLQEQHDAEIFELKSEVLWLESRMLELELQGVQAAPAEADPRHHLALAQELGHKPGGQGHSYRHRLQAQSADFLTPENKQQELGDGTGVQPPSLKLPAEAKRVQEQHGAQQKALETCVAALGQQLQGAWEEARTAGQRLAAQAVVLSSCRGQLHQAEAENAQLQLQLKKLNEAYAIRLQHCAQTVAGYADGAGPKPTAAALRTFLETTLEDIRTAHHSREQQLARAARFYRKCLADLSRRHEELLTAHRAQGTPRAAFGAAPSDVALLPLSTVTESSHQTEDQARLEKELQKLKAQKGSSEVSQGGTVEPQGLEAASWAQIRQNLQEFARGTQSWSGSGHSCWSAPRWQRSSFLSYRSTWTSTWEGGPGIRGPRFQALAAGLVHN", "length": 480 }, "evidence": [ { "id": "A0A8V0Z6B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6B2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2IDD5-1", "protein_name": "Coiled-coil domain-containing protein 78", "gene_name": "CCDC78", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHAATTGPRPGPPSRRVENVVLRAKDWLPGAPGGTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLSSPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRSTQSWNGSGHSCWSGPRWLKSNFLSYRSTWTSTWAGTSTKS", "length": 438 }, "evidence": [ { "id": "A0A8V0Z6B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3Z5T1-1", "protein_name": "Coiled-coil domain-containing protein 78", "gene_name": "Ccdc78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQRPELLSSMEYVASPDPKPGVPLRVAENVAPGAEDWLPSASGHLAWATSLETEHQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREILRLESRVLELELHGNGACQGHKVQPMANLGQHQVPPLEPPGGQQKLQEELKWLLEHHRARQQALETQVGVLSQQLQGAREEARTTGQQLASQAMVLASCKGQLRQAEAENTQLQLQLKKMNEEYAVRLQHYARETVENASSTNQAALQAFLESTLQDIRAAHRTREQQLAQAARTYRKRLADLNQRQELLLTTCRATFATAINLEPLPMHWATELSHPRENEYGRHRTLLLYPEKGSGETSKENKSQPLALDTASWAQIQQRLQDFSQDTQAELERERAQLMVRATMAEQQLSELQEYVDQHLGRYKQEILKLRKLVNIGDPQGVEAVSSPGSGGARL", "length": 437 }, "evidence": [ { "id": "A0A8V0Z6B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELZ7-1", "protein_name": "Coiled-coil domain containing 78", "gene_name": "Ccdc78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQFSLRQDRQSLRSTEALATLTTLPVTARKQATIRRIRGQGFLEDSIASMEYRAAPDPRPWASLQVAENVVPGAEDWLPRVSGNPARATSLETEPQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREVLRLESRVLELEMHGTGACQGQTVQPAANPGQYQVSPQEPSGGQQRLQEELKWVLEHHRVRQQALETQVGALSRQLQGAREEARTAGQQLAAQAMVLSSCKDQLRQAEAENAQLQLQLKKLNEEYAVRLQRYAKETAETSSSTNQASLQAFLEAALQDIRAAHRSREQQLAQAARAYRKRLADLNQRQELLLTTCRATFATAINLEPSPLHWAAELSHPRENEYGPHRTTLLLYPEKGSGEASKEDKSQPLALDTASWVQIQQKLQDFSQDTQAELERERAQLMVRATMAEQQLSELQEYVDQHLGRYKQEILKLRKLANSGDSQGVESMPSTRPRRPRTQSH", "length": 481 }, "evidence": [ { "id": "A0A8V0Z6B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B2" }, { "id": "PF14739", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4472", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 170, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 432, "end_pos": 434 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6G0-1", "uniprot_ac": "A0A8V0Z6G0", "uniprot_id": "A0A8V0Z6G0_CHICK", "mass": { "chemical_mass": 221545.0, "monoisotopic_mass": 221545.0 }, "refseq": {}, "gene_names": [ { "name": "COL6A6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ] } ], "protein_names": [ { "name": "Collagen type VI alpha 6 chain", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL6A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0", "locus": {} } ], "crossref": [ { "id": "cd01450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZS4", "url": "https://www.orthodb.org/?gene=A0A8V0YZS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6E9", "url": "https://www.orthodb.org/?gene=A0A8V0Z6E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6G0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YZS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDWKSVLVLLLVSTFGTIDAQQTAACSKATVADVVFIVDTSTSIAQENFQKVKNFLSSLVSSLDIGLDMIRVGLAQYSDEAYQVFLLNQYLLKSDVLDQIGNLPYRGGETYTGRALDFVSTRYFTESAGSRAKGYVPQLAVLITSGESNDEVEQPAKKLRYRGISIYVVGIGIQNTTELQQIASKPFRRYLYSIGSFNDLPDLSTRLLQNFCIAIESQIQAFAKRYADVIFLIDSTENMKPSTSERVKHFISQVVRQLDVGLNKYRIGLAQFSGIGKVEFLLNTYENKEEVLDHIQRSIAFTGGSLQNESAIEFLKKTFLMNGAGSRLSEGTPQVVVIFTSSGSRNSIMEEAWVLEDMGVKVTLVDVEYFDKIEATVREPSSKVYQIYEVESIDPVQQNIVNNIETSLQMLYDLDSSAPAVCSSATVADIVFLVDESSKIGSKNFQLIRAFLLKIVNALDIAPSNVRVGLVLYSNEPRLEFTLDTFKDKLEILNYLKNLPYRGGQAYTGIAIEFLRNKVFTQEAGSRKKQGVQQIAVVITDGQSLDDYIEPASKLRRESVTVYAVGVKNITEGSKLDKIATYPPRNHVTTLKYFLQLSNIRWKIKKQLCNEIVTKTFVVPLQSRSLKKGCMDTEEADIYFLIDGSGSIYPSDFKDMKTFMNEVIRIFQLGANNVRFGVVQYASESKTEIIIGQHSQMMRLTEAIENINQIGGGTRTGNALRSMKSLFQVAYRENVPQILIVITDGKSEDKVNQAARDLRQQGIVIYAIGIKDAVQQELEEIAETKNRMFFVNDFDSLKHIKHEIVQEVCSTNVCKNVRADIVFLVDSSNSIRAAEFQKIKDFMQSFVIKVDVGLDNVRIGLIQFSSEIREEFQLDRYSTIADVQRAIQEMQQIKLGTLTGKALTFAASYFDRPKGGRPELKQYLIVITDGEAQDSVKSPARAIRDKGITIYAIDMLQANNSQLVEITGAQDKVFFESEMNFSEKQILFEICNLQKLCKRAEAADIMFVVHGSSGVTDLQFKNMLQLVEAVVNNSVVGKDNVQFGVLVYSSNPEVQFSLNSYASKSQIREAVFSLKPLSGQPFTARALSFARQTFGVNYGGRASSLAVARILVLITDEPTVPSDRDNLPMAIRALKEDKIVLIAVGVSKASREELEEITEDQKRLFFAQSYDALENMHENLTQTVCESSKPVCSNHVADLIFLIDGSESISENSFSTMKTFMKDVVDSFDISRDKVRLGVVQYSQEPQREFYLNEFYSDTIIKEQINRIEQLRSSTFTGKGLRFVQSLFEPANGGRKNQGVSQNLVVITDGYSADSVDDAAMALRSNGIHVFAVGVGIVNSFELLRIAGDARRVFTVENFNALKTIKSTIINEICEPEDPASQDCNIDLAIAIDISRHMQSASSLLMKQKLQTFLPRLLFQMKSLPSISCNAGSPVNIRFKFQVLSQTKQFLFNSDFEDYDEEIIQKFLDAQTAVDTYLNVDFLQAVQETFFSATSAKVKVLLVFSDGLDDSLEDLRKAANAFRLKGLDALLLVGLDNTQNLTTLREIEFGRGFGYNEPLSVGFPEIASILQRNLDTVAERKCCNVICKCLGETGDHGGWGNPGRKGSTGYRGSPGHPGDEGGIGDRGPAGFNGTRGDRGCAGARGRKGSRGHQGSQGEHGESGFDGIDGEQGEHGSPGFPGEKGSPGKRGRKGPRGEPGERGEPGLRGDHGDPGIDNNIAGPKGEKGKPAWQGDPGPRGLQGEQGHAGPDGAEGRRGAPGIKGEQGEMGETGYPGDPGLPGPQGTRGPQGIRGPPGPQGMPGSQASLGPPGLPGSNGKPGARGAKGEPGDPGEKGPVGPPGPRGIPGVDGRDVYGPEGNKGAKGESGFIGYPGPEGEDGDPGISGAKGPKGIRGRRGNAGTPGSLGDPGDQGPSGPMGAKGQRGTVLMEPCELVNFTRKNCPCSSDTDICPVYPTEVVFALDMSEGVTPAAFERMRNIVMSLLKTIKISESNCPTGARVSIVSFNTNRIPKNTTCFYRQSREYL", "length": 2025, "header": "tr|A0A8V0Z6G0-1|A0A8V0Z6G0_CHICK Isoform 1 of Collagen type VI alpha 6 chain OS=Gallus gallus OX=9031 GN=COL6A6 PE=1 SV=1 CANONICAL=A0A8V0Z6G0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0/entry#A0A8V0YZS4-1", "sequence": { "sequence": "MDDWKSVLVLLLVSTFGTIDAQQTACSKATVADVVFIVDTSTSIAQENFQKVKNFLSSLVSSLDIGLDMIRVGLAQYSDEAYQVFLLNQYLLKSDVLDQIGNLPYRGGETYTGRALDFVSTRYFTESAGSRAKGYVPQLAVLITSGESNDEVEQPAKKLRYRGISIYVVGIGIQNTTELQQIASKPFRRYLYSIGSFNDLPDLSTRLLQNFCIAIESQIQAFAKRYADVIFLIDSTENMKPSTSERVKHFISQVVRQLDVGLNKYRIGLAQFSGIGKVEFLLNTYENKEEVLDHIQRSIAFTGGSLQNESAIEFLKKTFLMNGAGSRLSEGTPQVVVIFTSSGSRNSIMEEAWVLEDMGVKVTLVDVEYFDKIEATVREPSSKVYQIYEVESIDPVQQNIVNNIETSLQMLYDLDSSAPAVCSSATVADIVFLVDESSKIGSKNFQLIRAFLLKIVNALDIAPSNVRVGLVLYSNEPRLEFTLDTFKDKLEILNYLKNLPYRGGQAYTGIAIEFLRNKVFTQEAGSRKKQGVQQIAVVITDGQSLDDYIEPASKLRRESVTVYAVGVKNITEGSKLDKIATYPPRNHVTTLKYFLQLSNIRWKIKKQLCNEIVTKTFVVPLQSRSLKKGCMDTEEADIYFLIDGSGSIYPSDFKDMKTFMNEVIRIFQLGANNVRFGVVQYASESKTEIIIGQHSQMMRLTEAIENINQIGGGTRTGNALRSMKSLFQVAYRENVPQILIVITDGKSEDKVNQAARDLRQQGIVIYAIGIKDAVQQELEEIAETKNRMFFVNDFDSLKHIKHEIVQEVCSTNVCKNVRADIVFLVDSSNSIRAAEFQKIKDFMQSFVIKVDVGLDNVRIGLIQFSSEIREEFQLDRYSTIADVQRAIQEMQQIKLGTLTGKALTFAASYFDRPKGGRPELKQYLIVITDGEAQDSVKSPARAIRDKGITIYAIDMLQANNSQLVEITGAQDKVFFESEMNFSEKQILFEICNLQKLCKRAEAADIMFVVHGSSGVTDLQFKNMLQLVEAVVNNSVVGKDNVQFGVLVYSSNPEVQFSLNSYASKSQIREAVFSLKPLSGQPFTARALSFARQTFGVNYGGRASSLAVARILVLITDEPTVPSDRDNLPMAIRALKEDKIVLIAVGVSKASREELEEITEDQKRLFFAQSYDALENMHENLTQTVCESSKPVCSNHVADLIFLIDGSESISENSFSTMKTFMKDVVDSFDISRDKVRLGVVQYSQEPQREFYLNEFYSDTIIKEQINRIEQLRSSTFTGKGLRFVQSLFEPANGGRKNQGVSQNLVVITDGYSADSVDDAAMALRSNGIHVFAVGVGIVNSFELLRIAGDARRVFTVENFNALKTIKSTIINEICEPEDPASQDCNIDLAIAIDISRHMQSASSLLMKQKLQTFLPRLLFQMKSLPSISCNAGSPVNIRFKFQVLSQTKQFLFNSDFEDYDEEIIQKFLDAQTAVDTYLNVDFLQAVQETFFSATSAKVKVLLVFSDGLDDSLEDLRKAANAFRLKGLDALLLVGLDNTQNLTTLREIEFGRGFGYNEPLSVGFPEIASILQRNLDTVAERKCCNVICKCLGETGDHGGWGNPGRKGSTGYRGSPGHPGDEGGIGDRGPAGFNGTRGDRGCAGARGRKGSRGHQGSQGEHGESGFDGIDGEQGEHGSPGFPGEKGSPGKRGRKGPRGEPGERGEPGLRGDHGDPGIDNNIAGPKGEKGKPAWQGDPGPRGLQGEQGHAGPDGAEGRRGAPGIKGEQGEMGETGYPGDPGLPGPQGTRGPQGIRGPPGPQGMPGSQASLGPPGLPGSNGKPGARGAKGEPGDPGEKGPVGPPGPRGIPGVDGRDVYGPEGNKGAKGESGFIGYPGPEGEDGDPGISGAKGPKGIRGRRGNAGTPGSLGDPGDQGPSGPMGAKGQRGTVLMEPCELVNFTRKNCHTDICPVYPTEVVFALDMSEGVTPAAFERMRNIVMSLLKTIKISESNCPTGARVSIVSFNTNRIPKNTTCFYRQSREYL", "length": 2020, "header": "tr|A0A8V0YZS4-1|A0A8V0Z6G0_CHICK Computationally mapped isoform of Collagen type VI alpha 6 chain OS=Gallus gallus OX=9031 GN=COL6A6 PE=1 SV=1 CANONICAL=A0A8V0Z6G0-1" }, "locus": { "chromosome": "2", "start_pos": 41496668, "end_pos": 41460431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044539.1", "url": "https://www.ensembl.org/id/ENSGALT00010044539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026511.1", "url": "https://www.ensembl.org/id/ENSGALP00010026511.1" } ] } }, { "isoform_ac": "A0A8V0Z6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0/entry#A0A8V0Z6E9-1", "sequence": { "sequence": "MDDWKSVLVLLLVSTFGTIDAQQTACSKATVADVVFIVDTSTSIAQENFQKVKNFLSSLVSSLDIGLDMIRVGLAQYSDEAYQVFLLNQYLLKSDVLDQIGNLPYRGGETYTGRALDFVSTRYFTESAGSRAKGYVPQLAVLITSGESNDEVEQPAKKLRYRGISIYVVGIGIQNTTELQQIASKPFRRYLYSIGSFNDLPDLSTRLLQNFCIAIESQIQAFAKRYADVIFLIDSTENMKPSTSERVKHFISQVVRQLDVGLNKYRIGLAQFSGIGKVEFLLNTYENKEEVLDHIQRSIAFTGGSLQNESAIEFLKKTFLMNGAGSRLSEGTPQVVVIFTSSGSRNSIMEEAWVLEDMGVKVTLVDVEYFDKIEATVREPSSKVYQIYEVESIDPVQQNIVNNIETSLQMLYDLDSSAPAVCSSATVADIVFLVDESSKIGSKNFQLIRAFLLKIVNALDIAPSNVRVGLVLYSNEPRLEFTLDTFKDKLEILNYLKNLPYRGGQAYTGIAIEFLRNKVFTQEAGSRKKQGVQQIAVVITDGQSLDDYIEPASKLRRESVTVYAVGVKNITEGSKLDKIATYPPRNHVTTLKYFLQLSNIRWKIKKQLCNEIVTKTFVVPLQSRSLKKGCMDTEEADIYFLIDGSGSIYPSDFKDMKTFMNEVIRIFQLGANNVRFGVVQYASESKTEIIIGQHSQMMRLTEAIENINQIGGGTRTGNALRSMKSLFQVAYRENVPQILIVITDGKSEDKVNQAARDLRQQGIVIYAIGIKDAVQQELEEIAETKNRMFFVNDFDSLKHIKHEIVQEVCSTNVCKNVRADIVFLVDSSNSIRAAEFQKIKDFMQSFVIKVDVGLDNVRIGLIQFSSEIREEFQLDRYSTIADVQRAIQEMQQIKLGTLTGKALTFAASYFDRPKGGRPELKQYLIVITDGEAQDSVKSPARAIRDKGITIYAIDMLQANNSQLVEITGAQDKVFFESEMNFSEKQILFEICNLQKLCKRAEAADIMFVVHGSSGVTDLQFKNMLQLVEAVVNNSVVGKDNVQFGVLVYSSNPEVQFSLNSYASKSQIREAVFSLKPLSGQPFTARALSFARQTFGVNYGGRASSLAVARILVLITDEPTVPSDRDNLPMAIRALKEDKIVLIAVGVSKASREELEEITEDQKRLFFAQSYDALENMHENLTQTVCESSKPVCSNHVADLIFLIDGSESISENSFSTMKTFMKDVVDSFDISRDKVRLGVVQYSQEPQREFYLNEFYSDTIIKEQINRIEQLRSSTFTGKGLRFVQSLFEPANGGRKNQGVSQNLVVITDGYSADSVDDAAMALRSNGIHVFAVGVGIVNSFELLRIAGDARRVFTVENFNALKTIKSTIINEICEPEDPASQDCNIDLAIAIDISRHMQSASSLLMKQKLQTFLPRLLFQMKSLPSISCNAGSPVNIRFKFQVLSQTKQFLFNSDFEDYDEEIIQKFLDAQTAVDTYLNVDFLQAVQETFFSATSAKVKVLLVFSDGLDDSLEDLRKAANAFRLKGLDALLLVGLDNTQNLTTLREIEFGRGFGYNEPLSVGFPEIASILQRNLDTVAERKCCNVICKCLGETGDHGGWGNPGRKGSTGYRGSPGHPGDEGGIGDRGPAGFNGTRGDRGCAGARGRKGSRGHQGSQGEHGESGFDGIDGEQGEHGSPGFPGEKGSPGKRGRKGPRGEPGERGEPGLRGDHGDPGIDNNIAGPKGEKGKPAWQGDPGPRGLQGEQGHAGPDGAEGRRGAPGIKGEQGEMGETGYPGDPGLPGPQGTRGPQGIRGPPGPQGMPGSQASLGPPGLPGSNGKPGARGAKGEPGDPGEKGPVGPPGPRGIPGVDGRDVYGPEGNKGAKGESGFIGYPGPEGEDGDPGISGAKGPKGIRGRRGNAGTPGSLGDPGDQGPSGPMGAKGQRGTVLMEPCELVNFTRKNCPCSSDTDICPVYPTEVVFALDMSEGVTPAAFERMRNIVMSLLKTIKISESNCPTGARVSIVSFNTNRIPKNTTCFYRQSREYL", "length": 2024, "header": "tr|A0A8V0Z6E9-1|A0A8V0Z6E9_CHICK Computationally mapped isoform of Collagen type VI alpha 6 chain OS=Gallus gallus OX=9031 GN=COL6A6 PE=1 SV=1 CANONICAL=A0A8V0Z6G0-1" }, "locus": { "chromosome": "2", "start_pos": 41496668, "end_pos": 41460431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044525.1", "url": "https://www.ensembl.org/id/ENSGALT00010044525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026505.1", "url": "https://www.ensembl.org/id/ENSGALP00010026505.1" } ] } }, { "isoform_ac": "A0A8V0Z6G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0/entry#A0A8V0Z6G0-1", "sequence": { "sequence": "MDDWKSVLVLLLVSTFGTIDAQQTAACSKATVADVVFIVDTSTSIAQENFQKVKNFLSSLVSSLDIGLDMIRVGLAQYSDEAYQVFLLNQYLLKSDVLDQIGNLPYRGGETYTGRALDFVSTRYFTESAGSRAKGYVPQLAVLITSGESNDEVEQPAKKLRYRGISIYVVGIGIQNTTELQQIASKPFRRYLYSIGSFNDLPDLSTRLLQNFCIAIESQIQAFAKRYADVIFLIDSTENMKPSTSERVKHFISQVVRQLDVGLNKYRIGLAQFSGIGKVEFLLNTYENKEEVLDHIQRSIAFTGGSLQNESAIEFLKKTFLMNGAGSRLSEGTPQVVVIFTSSGSRNSIMEEAWVLEDMGVKVTLVDVEYFDKIEATVREPSSKVYQIYEVESIDPVQQNIVNNIETSLQMLYDLDSSAPAVCSSATVADIVFLVDESSKIGSKNFQLIRAFLLKIVNALDIAPSNVRVGLVLYSNEPRLEFTLDTFKDKLEILNYLKNLPYRGGQAYTGIAIEFLRNKVFTQEAGSRKKQGVQQIAVVITDGQSLDDYIEPASKLRRESVTVYAVGVKNITEGSKLDKIATYPPRNHVTTLKYFLQLSNIRWKIKKQLCNEIVTKTFVVPLQSRSLKKGCMDTEEADIYFLIDGSGSIYPSDFKDMKTFMNEVIRIFQLGANNVRFGVVQYASESKTEIIIGQHSQMMRLTEAIENINQIGGGTRTGNALRSMKSLFQVAYRENVPQILIVITDGKSEDKVNQAARDLRQQGIVIYAIGIKDAVQQELEEIAETKNRMFFVNDFDSLKHIKHEIVQEVCSTNVCKNVRADIVFLVDSSNSIRAAEFQKIKDFMQSFVIKVDVGLDNVRIGLIQFSSEIREEFQLDRYSTIADVQRAIQEMQQIKLGTLTGKALTFAASYFDRPKGGRPELKQYLIVITDGEAQDSVKSPARAIRDKGITIYAIDMLQANNSQLVEITGAQDKVFFESEMNFSEKQILFEICNLQKLCKRAEAADIMFVVHGSSGVTDLQFKNMLQLVEAVVNNSVVGKDNVQFGVLVYSSNPEVQFSLNSYASKSQIREAVFSLKPLSGQPFTARALSFARQTFGVNYGGRASSLAVARILVLITDEPTVPSDRDNLPMAIRALKEDKIVLIAVGVSKASREELEEITEDQKRLFFAQSYDALENMHENLTQTVCESSKPVCSNHVADLIFLIDGSESISENSFSTMKTFMKDVVDSFDISRDKVRLGVVQYSQEPQREFYLNEFYSDTIIKEQINRIEQLRSSTFTGKGLRFVQSLFEPANGGRKNQGVSQNLVVITDGYSADSVDDAAMALRSNGIHVFAVGVGIVNSFELLRIAGDARRVFTVENFNALKTIKSTIINEICEPEDPASQDCNIDLAIAIDISRHMQSASSLLMKQKLQTFLPRLLFQMKSLPSISCNAGSPVNIRFKFQVLSQTKQFLFNSDFEDYDEEIIQKFLDAQTAVDTYLNVDFLQAVQETFFSATSAKVKVLLVFSDGLDDSLEDLRKAANAFRLKGLDALLLVGLDNTQNLTTLREIEFGRGFGYNEPLSVGFPEIASILQRNLDTVAERKCCNVICKCLGETGDHGGWGNPGRKGSTGYRGSPGHPGDEGGIGDRGPAGFNGTRGDRGCAGARGRKGSRGHQGSQGEHGESGFDGIDGEQGEHGSPGFPGEKGSPGKRGRKGPRGEPGERGEPGLRGDHGDPGIDNNIAGPKGEKGKPAWQGDPGPRGLQGEQGHAGPDGAEGRRGAPGIKGEQGEMGETGYPGDPGLPGPQGTRGPQGIRGPPGPQGMPGSQASLGPPGLPGSNGKPGARGAKGEPGDPGEKGPVGPPGPRGIPGVDGRDVYGPEGNKGAKGESGFIGYPGPEGEDGDPGISGAKGPKGIRGRRGNAGTPGSLGDPGDQGPSGPMGAKGQRGTVLMEPCELVNFTRKNCPCSSDTDICPVYPTEVVFALDMSEGVTPAAFERMRNIVMSLLKTIKISESNCPTGARVSIVSFNTNRIPKNTTCFYRQSREYL", "length": 2025, "header": "tr|A0A8V0Z6G0-1|A0A8V0Z6G0_CHICK Isoform 1 of Collagen type VI alpha 6 chain OS=Gallus gallus OX=9031 GN=COL6A6 PE=1 SV=1 CANONICAL=A0A8V0Z6G0-1" }, "locus": { "chromosome": "2", "start_pos": 41496668, "end_pos": 41460431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044545.1", "url": "https://www.ensembl.org/id/ENSGALT00010044545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026515.1", "url": "https://www.ensembl.org/id/ENSGALP00010026515.1" } ] } }, { "isoform_ac": "A0A8V0ZDA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0/entry#A0A8V0ZDA9-1", "sequence": { "sequence": "MDDWKSVLVLLLVSTFGTIDAQQTAACSKATVADVVFIVDTSTSIAQENFQKVKNFLSSLVSSLDIGLDMIRVGLAQYSDEAYQVFLLNQYLLKSDVLDQIGNLPYRGGETYTGRALDFVSTRYFTESAGSRAKGYVPQLAVLITSGESNDEVEQPAKKLRYRGISIYVVGIGIQNTTELQQIASKPFRRYLYSIGSFNDLPDLSTRLLQNFCIAIESQIQAFAKRYADVIFLIDSTENMKPSTSERVKHFISQVVRQLDVGLNKYRIGLAQFSGIGKVEFLLNTYENKEEVLDHIQRSIAFTGGSLQNESAIEFLKKTFLMNGAGSRLSEGTPQVVVIFTSSGSRNSIMEEAWVLEDMGVKVTLVDVEYFDKIEATVREPSSKVYQIYEVESIDPVQQNIVNNIETSLQMLYDLDSSAPAVCSSATVADIVFLVDESSKIGSKNFQLIRAFLLKIVNALDIAPSNVRVGLVLYSNEPRLEFTLDTFKDKLEILNYLKNLPYRGGQAYTGIAIEFLRNKVFTQEAGSRKKQGVQQIAVVITDGQSLDDYIEPASKLRRESVTVYAVGVKNITEGSKLDKIATYPPRNHVTTLKYFLQLSNIRWKIKKQLCNEIVTKTFVVPLQSRSLKKGCMDTEEADIYFLIDGSGSIYPSDFKDMKTFMNEVIRIFQLGANNVRFGVVQYASESKTEIIIGQHSQMMRLTEAIENINQIGGGTRTGNALRSMKSLFQVAYRENVPQILIVITDGKSEDKVNQAARDLRQQGIVIYAIGIKDAVQQELEEIAETKNRMFFVNDFDSLKHIKHEIVQEVCSTNVCKNVRADIVFLVDSSNSIRAAEFQKIKDFMQSFVIKVDVGLDNVRIGLIQFSSEIREEFQLDRYSTIADVQRAIQEMQQIKLGTLTGKALTFAASYFDRPKGGRPELKQYLIVITDGEAQDSVKSPARAIRDKGITIYAIDMLQANNSQLVEITGAQDKVFFESEMNFSEKQILFEICNLQKLCKRAEAADIMFVVHGSSGVTDLQFKNMLQLVEAVVNNSVVGKDNVQFGVLVYSSNPEVQFSLNSYASKSQIREAVFSLKPLSGQPFTARALSFARQTFGVNYGGRASSLAVARILVLITDEPTVPSDRDNLPMAIRALKEDKIVLIAVGVSKASREELEEITEDQKRLFFAQSYDALENMHENLTQTVCESSKPVCSNHVADLIFLIDGSESISENSFSTMKTFMKDVVDSFDISRDKVRLGVVQYSQEPQREFYLNEFYSDTIIKEQINRIEQLRSSTFTGKGLRFVQSLFEPANGGRKNQGVSQNLVVITDGYSADSVDDAAMALRSNGIHVFAVGVGIVNSFELLRIAGDARRVFTVENFNALKTIKSTIINEICEPEDPASQDCNIDLAIAIDISRHMQSASSLLMKQKLQTFLPRLLFQMKSLPSISCNAGSPVNIRFKFQVLSQTKQFLFNSDFEDYDEEIIQKFLDAQTAVDTYLNVDFLQAVQETFFSATSAKVKVLLVFSDGLDDSLEDLRKAANAFRLKGLDALLLVGLDNTQNLTTLREIEFGRGFGYNEPLSVGFPEIASILQRNLDTVAERKCCNVICKCLGETGDHGGWGNPGRKGSTGYRGSPGHPGDEGGIGDRGPAGFNGTRGDRGCAGARGRKGSRGHQGSQGEHGESGFDGIDGEQGEHGSPGFPGEKGSPGKRGRKGPRGEPGERGEPGLRGDHGDPGIDNNIAGPKGEKGKPAWQGDPGPRGLQGEQGHAGPDGAEGRRGAPGIKGEQGEMGETGYPGDPGLPGPQGTRGPQGIRGPPGPQGMPGSQASLGPPGLPGSNGKPGARGAKGEPGDPGEKGPVGPPGPRGIPGVDGRDVYGPEGNKGAKGESGFIGYPGPEGEDGDPGISGAKGPKGIRGRRGNAGTPGSLGDPGDQGPSGPMGAKGQRGTVLMEPCELVNFTRKNCHTDICPVYPTEVVFALDMSEGVTPAAFERMRNIVMSLLKTIKISESNCPTGARVSIVSFNTNRIPKNTTCFYRQSREYL", "length": 2021, "header": "tr|A0A8V0ZDA9-1|A0A8V0ZDA9_CHICK Computationally mapped isoform of Collagen type VI alpha 6 chain OS=Gallus gallus OX=9031 GN=COL6A6 PE=1 SV=1 CANONICAL=A0A8V0Z6G0-1" }, "locus": { "chromosome": "2", "start_pos": 41496668, "end_pos": 41460431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044531.1", "url": "https://www.ensembl.org/id/ENSGALT00010044531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026507.1", "url": "https://www.ensembl.org/id/ENSGALP00010026507.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1902, "start_aa": "Thr", "end_pos": 1902, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1902", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1180, "end_pos": 1182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1541, "end_pos": 1543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1633, "end_pos": 1635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1936, "end_pos": 1938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2013, "end_pos": 2015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" }, { "start_pos": 981, "end_pos": 983, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G0" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 208, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1902 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1180, "end_pos": 1182 }, { "start_pos": 1541, "end_pos": 1543 }, { "start_pos": 1633, "end_pos": 1635 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 1936, "end_pos": 1938 }, { "start_pos": 2013, "end_pos": 2015 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 960, "end_pos": 962 }, { "start_pos": 981, "end_pos": 983 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6G4-1", "uniprot_ac": "A0A8V0Z6G4", "uniprot_id": "A0A8V0Z6G4_CHICK", "mass": { "chemical_mass": 58845.0, "monoisotopic_mass": 58845.0 }, "refseq": { "ac": "XP_040560173", "name": "HSPB1-associated protein 1 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560173" }, "gene_names": [ { "name": "HSPBAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4" } ] }, { "name": "HSPBAP1", "type": "synonym", "evidence": [ { "id": "XP_040560173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560173" } ] } ], "protein_names": [ { "name": "HSPB1 associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4/entry#names_and_taxonomy" } ] }, { "name": "HSPB1-associated protein 1 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_040560173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560173" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560173" } ] }, { "annotation": "May play a role in cellular stress response.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YZS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZS9#function" }, { "database": "UniProtKB", "id": "ARBA00037342", "url": "https://www.uniprot.org/uniprotkb/ARBA00037342#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U8#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSPBAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4", "locus": { "chromosome": "7", "start_pos": 26067267, "end_pos": 26100204, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018434", "url": "https://www.ensembl.org/id/ENSGALG00010018434" } ] } } ], "crossref": [ { "id": "A0A8V0Z6G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "424245", "url": "https://www.ncbi.nlm.nih.gov/gene/424245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZS9", "url": "https://www.orthodb.org/?gene=A0A8V0YZS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5U8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5V2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6G4", "url": "https://www.orthodb.org/?gene=A0A8V0Z6G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12461:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12461:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040560173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YZS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVADSRGRAAPGEDVKPFTPEKTREIVMSLQQPAVFCNMVGDWPALHWDVKHLSAMLDGKTIQFRIGLKAMDLVPQFETSCSYVKATLEEFLAWSSGQPSSLSGPFSCFEHSKYWAYADYKYIARIFEDKEEVFQDVRWSDFGFPGRSGKESTLWIGSEGANTPCHLDSYGCNLVLQIQGRKRWHLFPPGDTSFLYPTRIPYEESSIFSKVNVANPDLKRFPEFKNTRAHVVTLSPGQVLLVPKHWWHYVESIDPITVSINSWIELRKEGEKSLPKTVIRMTWTEERCHLNCVSAAWDLQDSDHEARVEEAITRTLVCALKSAESSSDGDPWLNPTEVEATSHEVNLQYLNQAVSVYFKCQKANVSEQAHRSSSGAEQETRAPCKRRKRQVSCEPQDCQLLNHEFSSSTFKAEELQKIPFGPHLVQVLPQSQETSSLGAGAVASDDRDLLHENEGGHFGKLHCTRKQLVMSNDCTTPANQMDSDSSPNALQAALSTNDLLDCLVNPHVIRLVAQLLLERARV", "length": 523, "header": "tr|A0A8V0Z6G4-1|A0A8V0Z6G4_CHICK Isoform 1 of HSPB1 associated protein 1 OS=Gallus gallus OX=9031 GN=HSPBAP1 PE=4 SV=1 CANONICAL=A0A8V0Z6G4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4/entry#A0A8V0YZS9-1", "sequence": { "sequence": "RSQITGRKACCDGGYLVGLPSDLTISWKAVSGSVTKAQWEQNTAVPQFETSCSYVKATLEEFLAWSSGQPSSLSGPFSCFEHSKYWAYADYKYIARIFEDKEEVFQDVRWSDFGFPGRSGKESTLWIGSEGANTPCHLDSYGCNLVLQIQGRKRWHLFPPGDTSFLYPTRIPYEESSIFSKVNVANPDLKRFPEFKNTRAHVVTLSPGQVLLVPKHWWHYVESIDPITVSINSWIELDSDHEARVEEAITRTLVCALKSAESSSDGDPWLNPTEVEATSHEVNLQYLNQAVSVYFKCQKANVSEQAHRSSSGAEQETRAPCKRRKRQVSCEPQDCQLLNHEFSSSTFKAEELQKIPFGPHLVQVLPQSQETSSLGAGAVASDDRDLLHENEGGHFGKLHCTRKQLVMSNDCTTPANQMDSDSSPNALQAALSTNDLLDCLVNPHVIRLVAQLLLERARV", "length": 459, "header": "tr|A0A8V0YZS9-1|A0A8V0Z6G4_CHICK Computationally mapped isoform of HSPB1 associated protein 1 OS=Gallus gallus OX=9031 GN=HSPBAP1 PE=4 SV=1 CANONICAL=A0A8V0Z6G4-1" }, "locus": { "chromosome": "7", "start_pos": 26084491, "end_pos": 26067306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044546.1", "url": "https://www.ensembl.org/id/ENSGALT00010044546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026516.1", "url": "https://www.ensembl.org/id/ENSGALP00010026516.1" } ] } }, { "isoform_ac": "A0A8V0Z5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4/entry#A0A8V0Z5U8-1", "sequence": { "sequence": "MIPMLWEIIGNTSCIVNHLSTAVVAVVLFCYFLYIGEDVKPFTPEKTREIVMSLQQPAVFCNMVGDWPALHWDVKHLSAMLDGKTIQFRIGLKAMDLVPQFETSCSYVKATLEEFLAWSSGQPSSLSGPFSCFEHSKYWAYADYKYIARIFEDKEEVFQDVRWSDFGFPGRSGKESTLWIGSEGANTPCHLDSYGCNLVLQIQGRKRWHLFPPGDTSFLYPTRIPYEESSIFSKVNVANPDLKRFPEFKNTRAHVVTLSPGQVLLVPKHWWHYVESIDPITVSINSWIELDSDHEARVEEAITRTLVCALKSAESSSDGDPWLNPTEVEATSHEVNLQYLNQAVSVYFKCQKANVSEQAHRSSSGAEQETRAPCKRRKRQVSCEPQDCQLLNHEFSSSTFKAEELQKIPFGPHLVQVLPQSQETSSLGAGAVASDDRDLLHENEGGHFGKLHCTRKQLVMSNDCTTPANQMDSDSSPNALQAALSTNDLLDCLVNPHVIRLVAQLLLERARV", "length": 512, "header": "tr|A0A8V0Z5U8-1|A0A8V0Z5U8_CHICK Computationally mapped isoform of HSPB1 associated protein 1 OS=Gallus gallus OX=9031 GN=HSPBAP1 PE=4 SV=1 CANONICAL=A0A8V0Z6G4-1" }, "locus": { "chromosome": "7", "start_pos": 26089740, "end_pos": 26067306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044550.1", "url": "https://www.ensembl.org/id/ENSGALT00010044550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026518.1", "url": "https://www.ensembl.org/id/ENSGALP00010026518.1" } ] } }, { "isoform_ac": "A0A8V0Z5V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4/entry#A0A8V0Z5V2-1", "sequence": { "sequence": "MAVADSRGRAAPVLISGQVFIFDNISGEDVKPFTPEKTREIVMSLQQPAVFCNMVGDWPALHWDVKHLSAMLDGKTIQFRIGLKAMDLVPQFETSCSYVKATLEEFLAWSSGQPSSLSGPFSCFEHSKYWAYADYKYIARIFEDKEEVFQDVRWSDFGFPGRSGKESTLWIGSEGANTPCHLDSYGCNLVLQIQGRKRWHLFPPGDTSFLYPTRIPYEESSIFSKVNVANPDLKRFPEFKNTRAHVVTLSPGQVLLVPKHWWHYVESIDPITVSINSWIELDSDHEARVEEAITRTLVCALKSAESSSDGDPWLNPTEVEATSHEVNLQYLNQAVSVYFKCQKANVSEQAHRSSSGAEQETRAPCKRRKRQVSCEPQDCQLLNHEFSSSTFKAEELQKIPFGPHLVQVLPQSQETSSLGAGAVASDDRDLLHENEGGHFGKLHCTRKQLVMSNDCTTPANQMDSDSSPNALQAALSTNDLLDCLVNPHVIRLVAQLLLERARV", "length": 503, "header": "tr|A0A8V0Z5V2-1|A0A8V0Z5V2_CHICK Computationally mapped isoform of HSPB1 associated protein 1 OS=Gallus gallus OX=9031 GN=HSPBAP1 PE=4 SV=1 CANONICAL=A0A8V0Z6G4-1" }, "locus": { "chromosome": "7", "start_pos": 26100175, "end_pos": 26067306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044558.1", "url": "https://www.ensembl.org/id/ENSGALT00010044558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026523.1", "url": "https://www.ensembl.org/id/ENSGALP00010026523.1" } ] } }, { "isoform_ac": "A0A8V0Z6G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4/entry#A0A8V0Z6G4-1", "sequence": { "sequence": "MAVADSRGRAAPGEDVKPFTPEKTREIVMSLQQPAVFCNMVGDWPALHWDVKHLSAMLDGKTIQFRIGLKAMDLVPQFETSCSYVKATLEEFLAWSSGQPSSLSGPFSCFEHSKYWAYADYKYIARIFEDKEEVFQDVRWSDFGFPGRSGKESTLWIGSEGANTPCHLDSYGCNLVLQIQGRKRWHLFPPGDTSFLYPTRIPYEESSIFSKVNVANPDLKRFPEFKNTRAHVVTLSPGQVLLVPKHWWHYVESIDPITVSINSWIELRKEGEKSLPKTVIRMTWTEERCHLNCVSAAWDLQDSDHEARVEEAITRTLVCALKSAESSSDGDPWLNPTEVEATSHEVNLQYLNQAVSVYFKCQKANVSEQAHRSSSGAEQETRAPCKRRKRQVSCEPQDCQLLNHEFSSSTFKAEELQKIPFGPHLVQVLPQSQETSSLGAGAVASDDRDLLHENEGGHFGKLHCTRKQLVMSNDCTTPANQMDSDSSPNALQAALSTNDLLDCLVNPHVIRLVAQLLLERARV", "length": 523, "header": "tr|A0A8V0Z6G4-1|A0A8V0Z6G4_CHICK Isoform 1 of HSPB1 associated protein 1 OS=Gallus gallus OX=9031 GN=HSPBAP1 PE=4 SV=1 CANONICAL=A0A8V0Z6G4-1" }, "locus": { "chromosome": "7", "start_pos": 26100175, "end_pos": 26067306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044554.1", "url": "https://www.ensembl.org/id/ENSGALT00010044554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026520.1", "url": "https://www.ensembl.org/id/ENSGALP00010026520.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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CANONICAL=A0A8V0Z6J6-1" }, "locus": { "chromosome": "22", "start_pos": 608972, "end_pos": 598697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044596.1", "url": "https://www.ensembl.org/id/ENSGALT00010044596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026547.1", "url": "https://www.ensembl.org/id/ENSGALP00010026547.1" } ] } }, { "isoform_ac": "A0A8V0Z6J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6/entry#A0A8V0Z6J6-1", "sequence": { "sequence": "MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKTQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVHEYLRSKLCSLYENDCIFDKFECCWNGSDSIVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKMN", "length": 442, "header": "tr|A0A8V0Z6J6-1|A0A8V0Z6J6_CHICK Isoform 1 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2A PE=1 SV=1 CANONICAL=A0A8V0Z6J6-1" }, "locus": { "chromosome": "22", "start_pos": 631610, "end_pos": 598697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044609.1", "url": "https://www.ensembl.org/id/ENSGALT00010044609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026557.1", "url": "https://www.ensembl.org/id/ENSGALP00010026557.1" } ] } }, { "isoform_ac": "A0A8V0Z6K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6/entry#A0A8V0Z6K9-1", "sequence": { "sequence": "MWLQIFPNLGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKTQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSIVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKMN", "length": 454, "header": "tr|A0A8V0Z6K9-1|A0A8V0Z6K9_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2A PE=1 SV=1 CANONICAL=A0A8V0Z6J6-1" }, "locus": { "chromosome": "22", "start_pos": 632882, "end_pos": 598697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044628.1", "url": "https://www.ensembl.org/id/ENSGALT00010044628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026572.1", "url": "https://www.ensembl.org/id/ENSGALP00010026572.1" } ] } }, { "isoform_ac": "A0A8V0Z7I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6/entry#A0A8V0Z7I6-1", "sequence": { "sequence": "MVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKTQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSIVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKMN", "length": 432, "header": "tr|A0A8V0Z7I6-1|A0A8V0Z7I6_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2A PE=1 SV=1 CANONICAL=A0A8V0Z6J6-1" }, "locus": { "chromosome": "22", "start_pos": 630109, "end_pos": 598697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044614.1", "url": "https://www.ensembl.org/id/ENSGALT00010044614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026561.1", "url": "https://www.ensembl.org/id/ENSGALP00010026561.1" } ] } }, { "isoform_ac": "A0A8V0ZDE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6/entry#A0A8V0ZDE7-1", "sequence": { "sequence": "EVGVRAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKTQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSIVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKMN", "length": 449, "header": "tr|A0A8V0ZDE7-1|A0A8V0ZDE7_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2A PE=1 SV=1 CANONICAL=A0A8V0Z6J6-1" }, "locus": { "chromosome": "22", "start_pos": 629612, "end_pos": 598697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044604.1", "url": "https://www.ensembl.org/id/ENSGALT00010044604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026554.1", "url": "https://www.ensembl.org/id/ENSGALP00010026554.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9860927", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9860927", "resource": "Reactome", "description": "Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of chromosome segregation", "id": "GO:0051983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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65085.0, "monoisotopic_mass": 65085.0 }, "refseq": {}, "gene_names": [ { "name": "COL9A2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ] } ], "protein_names": [ { "name": "Collagen type IX alpha 2 chain", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL9A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4", "locus": { "chromosome": "23", "start_pos": 5234092, "end_pos": 5248725, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017139", "url": "https://www.ensembl.org/id/ENSGALG00010017139" } ] } } ], "crossref": [ { "id": "A0A8V0Z6Z4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6Z4", "database": "AlphaFoldDB", "categories": [] }, { "id": "396524", "url": "https://www.ncbi.nlm.nih.gov/gene/396524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HAHAMEH", "url": "https://omabrowser.org/oma/group/HAHAMEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YZZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1C8", "url": "https://www.orthodb.org/?gene=A0A8V0Z1C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1E3", "url": "https://www.orthodb.org/?gene=A0A8V0Z1E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Z4", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": 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"A0A8V0Z1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSARRIISVTQLCLSSPPGELARGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGLTGAKGEPGPMGGAGLKGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGENGLPGIDGKDGTPGIPGVKGTAGQPGRPGPPGHRGQAGLPGQPGSKGGPGDKGEVGARGQQGITGAPGLMGEPGPRGEQGPQGVPGLKGDRGERGPVGAPGEQGRAGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPKGSTGDPGVHGLAGVKGEKGESGEPGPKGQQGIQGELGFPGPSGDAGSPGVRGYPGPPGPRGLLGERGVPGMPGQRGVAGRDAGDQHIIDVVLKMMQEQLAEVAVSAKRAALGGVGAMGPPGPPGPPGPPGEQGLHGPMGPRGVPGLLGAAGQIGNIGPKGKRGEKGERGDTGRGHPGMPGPPGIPGLPGIPGHALDGKDGERGPPGVPGDAGRPGSPGPAGLPGFCEPAACLGASAYASARLTEPGAVKGPLY", "length": 689, "header": "tr|A0A8V0Z6Z4-1|A0A8V0Z6Z4_CHICK Isoform 1 of Collagen type IX alpha 2 chain OS=Gallus gallus OX=9031 GN=COL9A2 PE=4 SV=1 CANONICAL=A0A8V0Z6Z4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4/entry#A0A8V0YZZ7-1", "sequence": { "sequence": "MGSHVVRWEHRGRGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGLTGAKGEPGPMGGAGLKGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGENGLPGIDGKDGTPGIPGVKGTAGQPGRPGPPGHRGQAGLPGQPGSKGGPGDKGEVGARGQQGITGAPGLMGEPGPRGEQGPQGVPGLKGDRGERGPVGAPGEQGRAGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPKGSTGDPGVHGLAGVKGEKGESGEPGPKGQQGIQGELGFPGPSGDAGSPGVRGYPGPPGPRGLLGERGVPGMPGQRGVAGRDAGDQHIIDVVLKMMQEQLAEVAVSAKRAALGGVGAMGPPGPPGPPGPPGEQGLHGPMGPRGVPGLLGAAGQIGNIGPKGKRGEKGERGDTGRGHPGMPGPPGIPGLPGIPGHALDGKDGERGPPGVPGDAGRPGSPGPAGLPGFCEPAACLGASAYASARLTEPGAVKGPLY", "length": 678, "header": "tr|A0A8V0YZZ7-1|A0A8V0Z6Z4_CHICK Computationally mapped isoform of Collagen type IX alpha 2 chain OS=Gallus gallus OX=9031 GN=COL9A2 PE=4 SV=1 CANONICAL=A0A8V0Z6Z4-1" }, "locus": { "chromosome": "23", "start_pos": 5245242, "end_pos": 5234501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041375.1", "url": "https://www.ensembl.org/id/ENSGALT00010041375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024240.1", "url": "https://www.ensembl.org/id/ENSGALP00010024240.1" } ] } }, { "isoform_ac": "A0A8V0Z1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4/entry#A0A8V0Z1C8-1", "sequence": { "sequence": "MAHRSSALCLLLLHAACLCLAQLRGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGENGLPGIDGKDGTPGIPGVKGTAGQPGRPGPPGHRGQAGLPGQPGSKGGPGDKGEVGARGQQGITGAPGLMGEPGPRGEQGPQGVPGLKGDRGERGPVGAPGEQGRAGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPKGSTGDPGVHGLAGVKGEKGESGEPGPKGQQGIQGELGFPGPSGDAGSPGVRGYPGPPGPRGLLGERGVPGMPGQRGVAGRDAGDQHIIDVVLKMMQEQLAEVAVSAKRAALGGVGAMGPPGPPGPPGPPGEQGLHGPMGPRGVPGLLGAAGQIGNIGPKGKRGEKGERGDTGRGHPGMPGPPGIPGLPGIPGHALDGKDGERGPPGVPGDAGRPGSPGPAGLPGFCEPAACLGASAYASARLTEPGAVKGPLY", "length": 671, "header": "tr|A0A8V0Z1C8-1|A0A8V0Z6Z4_CHICK Computationally mapped isoform of Collagen type IX alpha 2 chain OS=Gallus gallus OX=9031 GN=COL9A2 PE=4 SV=1 CANONICAL=A0A8V0Z6Z4-1" }, "locus": { "chromosome": "23", "start_pos": 5244138, "end_pos": 5234501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041370.1", "url": "https://www.ensembl.org/id/ENSGALT00010041370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024234.1", "url": "https://www.ensembl.org/id/ENSGALP00010024234.1" } ] } }, { "isoform_ac": "A0A8V0Z1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4/entry#A0A8V0Z1E3-1", "sequence": { "sequence": "MSGTFGLAVGAVLVLLLAQQAAQHRLVPLHVAHRFPRHGAAAAARPRVTAPPSRAPATSCFRPALWAGRRGEEPMAGGGGALRPPLVTSLSSLALIRLSPTLTAPLPAMAHRSSALCLLLLHAACLCLAQLRGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGLTGAKGEPGPMGGAGLKGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGENGLPGIDGKDGTPGIPGVKGTAGQPGRPGPPGHRGQAGLPGQPGSKGGPGDKGEVGARGQQGITGAPGLMGEPGPRGEQGPQGVPGLKGDRGERGPVGAPGEQGRAGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPKGSTGDPGVHGLAGVKGEKGESGEPGPKGQQGIQGELGFPGPSGDAGSPGVRGYPGPPGPRGLLGERGVPGMPGQRGVAGRDAGDQHIIDVVLKMMQEQLAEVAVSAKRAALGGVGAMGPPGPPGPPGPPGEQGLHGPMGPRGVPGLLGAAGQIGNIGPKGKRGEKGERGDTGRGHPGMPGPPGIPGLPGIPGHALDGKDGERGPPGVPGDAGRPGSPGPAGLPGFCEPAACLGASAYASARLTEPGAVKGPLY", "length": 797, "header": "tr|A0A8V0Z1E3-1|A0A8V0Z6Z4_CHICK Computationally mapped isoform of Collagen type IX alpha 2 chain OS=Gallus gallus OX=9031 GN=COL9A2 PE=4 SV=1 CANONICAL=A0A8V0Z6Z4-1" }, "locus": { "chromosome": "23", "start_pos": 5245600, "end_pos": 5234501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041388.1", "url": "https://www.ensembl.org/id/ENSGALT00010041388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024249.1", "url": "https://www.ensembl.org/id/ENSGALP00010024249.1" } ] } }, { "isoform_ac": "A0A8V0Z6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4/entry#A0A8V0Z6Z4-1", "sequence": { "sequence": "MPSARRIISVTQLCLSSPPGELARGPPGEPGPRGPPGPPGVPGADGIDGDKGSPGAPGSPGAKGEPGAPGPDGPPGKPGLDGLTGAKGEPGPMGGAGLKGQPGLPGPPGLPGPSLPGPPGLPGQVGLPGEIGVPGPKGDPGPDGPRGPPGPPGKPGPPGHIQGVEGSADFLCPTNCPPGPKGPQGLQGLKGHRGRPGALGEPGQQGKQGPKGDVGVSGEQGVPGPPGPQGQRGYPGMAGPKGETGPAGYKGMVGTIGAAGRPGREGPKGPPGDPGEKGELGGRGIRGPQGDIGPKGENGLPGIDGKDGTPGIPGVKGTAGQPGRPGPPGHRGQAGLPGQPGSKGGPGDKGEVGARGQQGITGAPGLMGEPGPRGEQGPQGVPGLKGDRGERGPVGAPGEQGRAGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPKGSTGDPGVHGLAGVKGEKGESGEPGPKGQQGIQGELGFPGPSGDAGSPGVRGYPGPPGPRGLLGERGVPGMPGQRGVAGRDAGDQHIIDVVLKMMQEQLAEVAVSAKRAALGGVGAMGPPGPPGPPGPPGEQGLHGPMGPRGVPGLLGAAGQIGNIGPKGKRGEKGERGDTGRGHPGMPGPPGIPGLPGIPGHALDGKDGERGPPGVPGDAGRPGSPGPAGLPGFCEPAACLGASAYASARLTEPGAVKGPLY", "length": 689, "header": "tr|A0A8V0Z6Z4-1|A0A8V0Z6Z4_CHICK Isoform 1 of Collagen type IX alpha 2 chain OS=Gallus gallus OX=9031 GN=COL9A2 PE=4 SV=1 CANONICAL=A0A8V0Z6Z4-1" }, "locus": { "chromosome": "23", "start_pos": 5248604, "end_pos": 5234501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041393.1", "url": "https://www.ensembl.org/id/ENSGALT00010041393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024252.1", "url": "https://www.ensembl.org/id/ENSGALP00010024252.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-186797", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186797", "resource": "Reactome", "description": "Signaling by PDGF" }, { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "pmid": "" }, { "name": "collagen type IX trimer", "id": "GO:0005594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z760-1", "uniprot_ac": "A0A8V0Z760", "uniprot_id": "A0A8V0Z760_CHICK", "mass": { "chemical_mass": 91226.0, "monoisotopic_mass": 91226.0 }, "refseq": { "ac": "XP_015139060", "name": "rho guanine nucleotide exchange factor 33 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139060" }, "gene_names": [ { "name": "ARHGEF33", "type": "recommended", "evidence": [ { "id": "A0A8V0Z760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760" } ] }, { "name": "ARHGEF33", "type": "synonym", "evidence": [ { "id": "XP_015139060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139060" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 33", "type": "synonym", "evidence": [ { "id": "A0A8V0Z760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 33 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_015139060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139060" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139060.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z760", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760", "locus": { "chromosome": "3", "start_pos": 16301426, "end_pos": 16271130, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017218", "url": "https://www.ensembl.org/id/ENSGALG00010017218" } ] } } ], "crossref": [ { "id": "A0A8V0Z760", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z760", "database": "AlphaFoldDB", "categories": [] }, { "id": "425963", "url": "https://www.ncbi.nlm.nih.gov/gene/425963", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z067", "url": "https://www.orthodb.org/?gene=A0A8V0Z067", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z760", "url": "https://www.orthodb.org/?gene=A0A8V0Z760", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46944:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46944:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z067", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z067", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z067-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z067-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z760", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z760-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTNKQEGETESVPVSTPATQISQLQALASELKAGFTEAMQELSRIQHGEYALEEKVKSCRCAMEEKVAEMKNSLNTFKEELSDAKSMIEEISAKQEEMQQKIEQLQQEKRRESRKVKAKRAQKDDHSSQTVPTPLQGSPFRSINLPEPVLINEDFTSLLHNVTYEKVSDTRIMPIGEGSVKVIGGPGTAIETEDSLKPSLTADGQTKVHLQSTVWKQPKDTKDWGDEYISKEQPERGKDVGQSRYSSADNIICEPSLAAKRQNIALELLESERKYVINLSLILKIKATLQGPDVKRSTKERSFFPNSLRYLVQQHVDLLHALQERVLSWPRQGILGDIFLKLTNDENNFLDYYVAYLRDLPECISLIHVVILKEVEEEIKSDLYILFFHIVQRIPEYLIHLQNVLKFTEQEHPDYYLLLVCVQRLRVFISHYSLLFQCNEDLLIQKRKKLKKSSLVKLYKGLTSQCTSQEVSPTPSTASIRDSGIHSEEAMQSFQPAPSSGTTTPHLLPQMKKPQPTVLENIQAVKPPDWEMESRKHERPENILASSQLTEQELKALTAPLQSIPEMEYEAPPADAVGNPERAIRTSVELLQDARNFAPSYEEFDYPGEVFTMPGPYEDDTFQNLALFENCSPASSESSLDICFLRPVNFTSEPERTDHALQPLPKSSTPVSSSTYKREMFHSKGKQLSRSLKELPRSAEGVSSRLYSTRSSSGSRLQQKQERNVQPHMISASSRSSQRSYFPPQRGAGEKPSFLEELHAEDNTRFCQKDDNEQTSFSDHNPRHEPKGGFRSSFRKLFKKK", "length": 802, "header": "tr|A0A8V0Z760-1|A0A8V0Z760_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 33 OS=Gallus gallus OX=9031 GN=ARHGEF33 PE=4 SV=1 CANONICAL=A0A8V0Z760-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z067-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760/entry#A0A8V0Z067-1", "sequence": { "sequence": "MLGRISVVKLQALASELKAGFTEAMQELSRIQHGEYALEEKVKSCRCAMEEKVAEMKNSLNTFKEELSDAKSMIEEISAKQEEMQQKIEQLQQEKRRESRKVKAKRAQKDDHSSQTVPTPLQGSPFRSINLPEPVLINEDFTSLLHNVTYEKVSDTRIMPIGEGSVKVIGGPGTAIETEDSLKPSLTADGQTKVHLQSTVWKQPKDTKDWGDEYISKEQPERGKDVGQSRYSSADNIICEPSLAAKRQNIALELLESERKYVINLSLILKIKATLQGPDVKRSTKERSFFPNSLRYLVQQHVDLLHALQERVLSWPRQGILGDIFLKLTNDENNFLDYYVAYLRDLPECISLIHVVILKEVEEEIKSDLYILFFHIVQRIPEYLIHLQNVLKFTEQEHPDYYLLLVCVQRLRVFISHYSLLFQCNEDLLIQKRKKLKKSSLVKLYKGLTSQCTSQEVSPTPSTASIRDSGIHSEEAMQSFQPAPSSGTTTPHLLPQMKKPQPTVLENIQAVKPPDWEMESRKHERPENILASSQLTEQELKALTAPLQSIPEMEYEAPPADAVGNPERAIRTSVELLQDARNFAPSYEEFDYPGEVFTMPGPYEDDTFQNLALFENCSPASSESSLDICFLRPVNFTSEPERTDHALQPLPKSSTPVSSSTYKREMFHSKGKQLSRSLKELPRSAEGVSSRLYSTRSSSGSRLQQKQERNVQPHMISASSRSSQRSYFPPQRGAGEKPSFLEELHAEDNTRFCQKDDNEQTSFSDHNPRHEPKGGFRSSFRKLFKKK", "length": 787, "header": "tr|A0A8V0Z067-1|A0A8V0Z760_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 33 OS=Gallus gallus OX=9031 GN=ARHGEF33 PE=4 SV=1 CANONICAL=A0A8V0Z760-1" }, "locus": { "chromosome": "3", "start_pos": 16299984, "end_pos": 16283934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041508.1", "url": "https://www.ensembl.org/id/ENSGALT00010041508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024306.1", "url": "https://www.ensembl.org/id/ENSGALP00010024306.1" } ] } }, { "isoform_ac": "A0A8V0Z760-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760/entry#A0A8V0Z760-1", "sequence": { "sequence": "MDTNKQEGETESVPVSTPATQISQLQALASELKAGFTEAMQELSRIQHGEYALEEKVKSCRCAMEEKVAEMKNSLNTFKEELSDAKSMIEEISAKQEEMQQKIEQLQQEKRRESRKVKAKRAQKDDHSSQTVPTPLQGSPFRSINLPEPVLINEDFTSLLHNVTYEKVSDTRIMPIGEGSVKVIGGPGTAIETEDSLKPSLTADGQTKVHLQSTVWKQPKDTKDWGDEYISKEQPERGKDVGQSRYSSADNIICEPSLAAKRQNIALELLESERKYVINLSLILKIKATLQGPDVKRSTKERSFFPNSLRYLVQQHVDLLHALQERVLSWPRQGILGDIFLKLTNDENNFLDYYVAYLRDLPECISLIHVVILKEVEEEIKSDLYILFFHIVQRIPEYLIHLQNVLKFTEQEHPDYYLLLVCVQRLRVFISHYSLLFQCNEDLLIQKRKKLKKSSLVKLYKGLTSQCTSQEVSPTPSTASIRDSGIHSEEAMQSFQPAPSSGTTTPHLLPQMKKPQPTVLENIQAVKPPDWEMESRKHERPENILASSQLTEQELKALTAPLQSIPEMEYEAPPADAVGNPERAIRTSVELLQDARNFAPSYEEFDYPGEVFTMPGPYEDDTFQNLALFENCSPASSESSLDICFLRPVNFTSEPERTDHALQPLPKSSTPVSSSTYKREMFHSKGKQLSRSLKELPRSAEGVSSRLYSTRSSSGSRLQQKQERNVQPHMISASSRSSQRSYFPPQRGAGEKPSFLEELHAEDNTRFCQKDDNEQTSFSDHNPRHEPKGGFRSSFRKLFKKK", "length": 802, "header": "tr|A0A8V0Z760-1|A0A8V0Z760_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 33 OS=Gallus gallus OX=9031 GN=ARHGEF33 PE=4 SV=1 CANONICAL=A0A8V0Z760-1" }, "locus": { "chromosome": "3", "start_pos": 16299984, "end_pos": 16276324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041515.1", "url": "https://www.ensembl.org/id/ENSGALT00010041515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024308.1", "url": "https://www.ensembl.org/id/ENSGALP00010024308.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z760", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z760" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 261, "end_pos": 436, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 475 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 650, "end_pos": 652 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6C2-1", "uniprot_ac": "A0A8V0Z6C2", "uniprot_id": "A0A8V0Z6C2_CHICK", "mass": { "chemical_mass": 37298.0, "monoisotopic_mass": 37298.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107051359", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" } ] } ], "protein_names": [ { "name": "N-acetyl-D-glucosamine kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.59", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#names_and_taxonomy" } ] }, { "name": "GlcNAc kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107051359", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd24078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0D1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6C2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7X0", "url": "https://www.orthodb.org/?gene=A0A8V0Z7X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12862", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12862", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12862:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12862:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01869", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01869", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEEAKRRSGTDRAVPLRSLGLALSGGAEEGAVTALLEELRRRCPELSRAYSVCSDAAGAMATACSSGGIVLIAGTGSNCQLLNPDGTESSCGGWGHMLGDEGSAYWIAQRAVKAVFDSMDNMEVSPHDIAYVREAMCRHFRISNRMGLLPHLYGSFQKADFAGFCLKVAEGARAGDALCRHVFTQAGQALARHVLAVLPRVDQVSGEWGGGGGDDPHAAPTLTSCPTRCPRLGGLLAPRTPPFHAEPVPGGAGAPHRLRGLRVEELGADERGLRAGVGWRPGGGNRGGLLPLQPPEVEALIGAGGGQPGGPACGAHVAIGLQQQRRCLLHTSLLKWGGEEGGCGAHGPPPPPPPWCGFG", "length": 360, "header": "tr|A0A8V0Z6C2-1|A0A8V0Z6C2_CHICK Isoform 1 of N-acetyl-D-glucosamine kinase OS=Gallus gallus OX=9031 GN=LOC107051359 PE=3 SV=1 CANONICAL=A0A8V0Z6C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#A0A8V0Z0D1-1", "sequence": { "sequence": "AEAEGLCTNHWLVGTAQCAERIVAMVEEAKRRSGTDRAVPLRSLGLALSGGAEEGAVTALLEELRRRCPELSRAYSVCSDAAGAMATACSSGGIVLIAGTGSNCQLLNPDGTESSCGGWGHMLGDEGSAYWIAQRAVKAVFDSMDNMEVSPHDIAYVREAMCRHFRISNRMGLLPHLYGSFQKADFAGFCLKVAEGARAGDALCRHVFTQAGQALARHVLAVLPRVDQSLFRGELGLPIVCVGSVWKSWELMREGFVQALVGGRGGEIGGVFSHFSLLRLKHSSALGGASLGARHVGHTLPLDYSNNADVFYTHHF", "length": 316, "header": "tr|A0A8V0Z0D1-1|A0A8V0Z6C2_CHICK Computationally mapped isoform of N-acetyl-D-glucosamine kinase OS=Gallus gallus OX=9031 GN=LOC107051359 PE=3 SV=1 CANONICAL=A0A8V0Z6C2-1" }, "locus": { "chromosome": "4", "start_pos": 90386870, "end_pos": 90351368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044771.1", "url": "https://www.ensembl.org/id/ENSGALT00010044771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026693.1", "url": "https://www.ensembl.org/id/ENSGALP00010026693.1" } ] } }, { "isoform_ac": "A0A8V0Z6C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#A0A8V0Z6C2-1", "sequence": { "sequence": "MVEEAKRRSGTDRAVPLRSLGLALSGGAEEGAVTALLEELRRRCPELSRAYSVCSDAAGAMATACSSGGIVLIAGTGSNCQLLNPDGTESSCGGWGHMLGDEGSAYWIAQRAVKAVFDSMDNMEVSPHDIAYVREAMCRHFRISNRMGLLPHLYGSFQKADFAGFCLKVAEGARAGDALCRHVFTQAGQALARHVLAVLPRVDQVSGEWGGGGGDDPHAAPTLTSCPTRCPRLGGLLAPRTPPFHAEPVPGGAGAPHRLRGLRVEELGADERGLRAGVGWRPGGGNRGGLLPLQPPEVEALIGAGGGQPGGPACGAHVAIGLQQQRRCLLHTSLLKWGGEEGGCGAHGPPPPPPPWCGFG", "length": 360, "header": "tr|A0A8V0Z6C2-1|A0A8V0Z6C2_CHICK Isoform 1 of N-acetyl-D-glucosamine kinase OS=Gallus gallus OX=9031 GN=LOC107051359 PE=3 SV=1 CANONICAL=A0A8V0Z6C2-1" }, "locus": { "chromosome": "4", "start_pos": 90386947, "end_pos": 90355227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044768.1", "url": "https://www.ensembl.org/id/ENSGALT00010044768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026690.1", "url": "https://www.ensembl.org/id/ENSGALP00010026690.1" } ] } }, { "isoform_ac": "A0A8V0Z7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2/entry#A0A8V0Z7X0-1", "sequence": { "sequence": "MVEEAKRRSGTDRAVPLRSLGLALSGGAEEGAVTALLEELRRRCPELSRAYSVCSDAAGAMATACSSGGIVLIAGTGSNCQLLNPDGTESSCGGWGHMLGDEGSAYWIAQRAVKAVFDSMDNMEVSPHDIAYVREAMCRHFRISNRMGLLPHLYGSFQKADFAGFCLKVAEGARAGDALCRHVFTQAGQALARHVLAVLPRVDQSLFRGELGLPIVCVGSVWKSWELMREGFVQPGGPACGAHVAIGLQQQRRCLLHTSLLKWGGEEGGCGAHGPPPPPPPWCGFG", "length": 286, "header": "tr|A0A8V0Z7X0-1|A0A8V0Z7X0_CHICK Computationally mapped isoform of N-acetyl-D-glucosamine kinase OS=Gallus gallus OX=9031 GN=LOC107051359 PE=3 SV=1 CANONICAL=A0A8V0Z6C2-1" }, "locus": { "chromosome": "4", "start_pos": 90386947, "end_pos": 90355227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044775.1", "url": "https://www.ensembl.org/id/ENSGALT00010044775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026697.1", "url": "https://www.ensembl.org/id/ENSGALP00010026697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosamine kinase activity", "id": "GO:0045127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-6803771", "name": "NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z6C2-1" ], "evidence": [ { "id": "R-GGA-6803771", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803771" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z6C2", "gene_name": "LOC107051359", "activity": [ { "ec_number": "2.7.1.59", "activity": "N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" } ] }, { "ec_number": "2.7.1.59", "activity": "", "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C2" }, { "id": "PF01869", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01869" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATPase BadF/BadG/BcrA/BcrD type", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 205, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.59", "ec_name": "N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H(+).", "evidence": [ { "id": "2.7.1.59", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.59" }, { "id": "2.7.1.59", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.59" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6W8-1", "uniprot_ac": "A0A8V0Z6W8", "uniprot_id": "A0A8V0Z6W8_CHICK", "mass": { "chemical_mass": 110746.0, "monoisotopic_mass": 110746.0 }, "refseq": {}, "gene_names": [ { "name": "CHTF18", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ] } ], "protein_names": [ { "name": "Chromosome transmission fidelity protein 18 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHTF18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8", "locus": { "chromosome": "14", "start_pos": 5984086, "end_pos": 5998429, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018505", "url": "https://www.ensembl.org/id/ENSGALG00010018505" } ] } } ], "crossref": [ { "id": "A0A8V0Z6W8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6W8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416531", "url": "https://www.ncbi.nlm.nih.gov/gene/416531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416531", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWLKGWE", "url": "https://omabrowser.org/oma/group/RWLKGWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0D6", "url": "https://www.orthodb.org/?gene=A0A8V0Z0D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6W8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46765", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46765", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46765:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46765:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-174411", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPGDEDDFTERFAAELEVLAELEDYPSSPGPRVSQFRSRKQLQDEAGPAVGPNAKKRSQECALHPSPPPSPPAGSPMALTPKPKRQRLEAVKKLNFGGDGELAPDVFQDAVTPVPGSASPRGPHAARSQAFPSPELEVSGLGPLQSSPPTENPKRVLRRPPILGDYINVTSSEGTRVFMAVRDDSSHIGIELRDSVGWNRPLHLLGVPFSYLKEQVYEEHRRRAVEVSQQLTETINSCSETSDEATEQPGDTGEEEPTPHCLWVDKFAPRRYIELLSDDYTNRCLLKWLKLWDTVVFGKEKPVKKAKPGAEAHPPFRQHKEQQNKWKTKAQLTEEILEAELDQHKRPKYKVALLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPETFRIRIEAATQMKSVLGAEEKPNCLIIDEIDGAPTASITVLLNIINSKEPEGEAAASGGRRRRREGSLLLRPVICICNDQYVPALRPLRQQAFLLSFPQTAPSRLAQRLGEIAQQQGMRADMGALLALCKKAENDIRSCINTLQFLHSRGQKELDVRVVQTMKIGLKDQNKGLFSIWQEIFQLPRVQRHHIGMDPSLPNHLLADEDEMSHLGVRTALTASSHRFHRVLHLASSSGEQEKLAQGLYENFLNMKLRDSSFSSVCLALEWLCFSDMLGRAVLHGQSFQLMRYLPFLPVAFHMLFAATSIPRLSYPSSHHEALAKLNHMQNLMVSMVSGITPSARSRAGQQSLVLEVLCLLLDIIAPKLRPVNTQLYSLKEKQQLAALISTMLAYNLTYHQERLPEGQYVYKLDPNAHRTAGVGAWPPCAAHPLLLSPPYAMAVTAPCPYGILRNVEDVCRFPDLPARKQLTYQAKQLIAHEIEMEKMRRTEAVLQARNLNEEPMEMGDVEMKAGGPPVPHNHQQRLEHIVRRAAVRDKPETDFFGRPIQRQQSAPALEAQPAEHDAIEHQMGKAVGRSDVWFRFNEGVSNAVRRNLYIRDLL", "length": 990, "header": "tr|A0A8V0Z6W8-1|A0A8V0Z6W8_CHICK Isoform 1 of Chromosome transmission fidelity protein 18 homolog OS=Gallus gallus OX=9031 GN=CHTF18 PE=3 SV=1 CANONICAL=A0A8V0Z6W8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8/entry#A0A8V0Z0D6-1", "sequence": { "sequence": "MESPGDEDDFTERFAAELEVLAELEDYPSSPGPRVSQFRSRKQLQDEAGPAVGPNAKKRSQECALHPSPPPSPPAGSPMALTPKPKRQRLEAVKKLNFGGDGELAPDVFQDAVTPVPGSASPRGPHAARSQAFPSPELEVSGLGPLQSSPPTENPKRVLRRPPILGDYINVTSSEGTRVFMAVRDDSSHIGIELRDSVGWNRPLHLLGVPFSYLKEQVYEEHRRRAVEVSQQLTETINSCSETSDEATEQPGDTGEEEPTPHCLWVDKFAPRRYIELLSDDYTNRCLLKWLKLWDTVVFGKEKPVKKAKPGAEAHPPFRQHKEQQNKWKTKAQLTEEILEAELDQHKRPKYKVALLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPETFRIRIEAATQMKSVLGAEEKPNCLIIDEIDGAPTASITVLLNIINSKEPEGEAAASGGRRRRREGSLLLRPVICICNDQYVPALRPLRQQAFLLSFPQTAPSRLAQRLGEIAQQQGMRADMGALLALCKKAENDIRSCINTLQFLHSRGQKELDVRVVQTMKIGLKDQNKGLFSIWQEIFQLPRVQRHHIGMDPSLPNHLLADEDEMSHLGVRTALTASSHRFHRVLHLASSSGEQEKLAQGLYENFLNMKLRDSSFSSVCLALEWLCFSDMLGRAVLHGQSFQLMRYLPFLPVAFHMLFAATSIPRLSYPSSHHEALAKLNHMQNLMVSMVSGITPSARSRAGQQSLVLEVLCLLLDIIAPKLRPVNTQLYSLKEKQQLAALISTMLAYNLTYHQERLPEGQYVYKLDPNVEDVCRFPDLPARKQLTYQAKQLIAHEIEMEKMRRTEAVLQARNLNEEPMEMGDVEMKAGGPPVPHNHQQRLEHIVRRAAVRDKPETDFFGRPIQRQQSAPALEAQPAEHDAIEHQMGKAVGRSDVWFRFNEGVSNAVRRNLYIRDLL", "length": 951, "header": "tr|A0A8V0Z0D6-1|A0A8V0Z6W8_CHICK Computationally mapped isoform of Chromosome transmission fidelity protein 18 homolog OS=Gallus gallus OX=9031 GN=CHTF18 PE=3 SV=1 CANONICAL=A0A8V0Z6W8-1" }, "locus": { "chromosome": "14", "start_pos": 5995276, "end_pos": 5984235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044777.1", "url": "https://www.ensembl.org/id/ENSGALT00010044777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026699.1", "url": "https://www.ensembl.org/id/ENSGALP00010026699.1" } ] } }, { "isoform_ac": "A0A8V0Z6W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8/entry#A0A8V0Z6W8-1", "sequence": { "sequence": "MESPGDEDDFTERFAAELEVLAELEDYPSSPGPRVSQFRSRKQLQDEAGPAVGPNAKKRSQECALHPSPPPSPPAGSPMALTPKPKRQRLEAVKKLNFGGDGELAPDVFQDAVTPVPGSASPRGPHAARSQAFPSPELEVSGLGPLQSSPPTENPKRVLRRPPILGDYINVTSSEGTRVFMAVRDDSSHIGIELRDSVGWNRPLHLLGVPFSYLKEQVYEEHRRRAVEVSQQLTETINSCSETSDEATEQPGDTGEEEPTPHCLWVDKFAPRRYIELLSDDYTNRCLLKWLKLWDTVVFGKEKPVKKAKPGAEAHPPFRQHKEQQNKWKTKAQLTEEILEAELDQHKRPKYKVALLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPETFRIRIEAATQMKSVLGAEEKPNCLIIDEIDGAPTASITVLLNIINSKEPEGEAAASGGRRRRREGSLLLRPVICICNDQYVPALRPLRQQAFLLSFPQTAPSRLAQRLGEIAQQQGMRADMGALLALCKKAENDIRSCINTLQFLHSRGQKELDVRVVQTMKIGLKDQNKGLFSIWQEIFQLPRVQRHHIGMDPSLPNHLLADEDEMSHLGVRTALTASSHRFHRVLHLASSSGEQEKLAQGLYENFLNMKLRDSSFSSVCLALEWLCFSDMLGRAVLHGQSFQLMRYLPFLPVAFHMLFAATSIPRLSYPSSHHEALAKLNHMQNLMVSMVSGITPSARSRAGQQSLVLEVLCLLLDIIAPKLRPVNTQLYSLKEKQQLAALISTMLAYNLTYHQERLPEGQYVYKLDPNAHRTAGVGAWPPCAAHPLLLSPPYAMAVTAPCPYGILRNVEDVCRFPDLPARKQLTYQAKQLIAHEIEMEKMRRTEAVLQARNLNEEPMEMGDVEMKAGGPPVPHNHQQRLEHIVRRAAVRDKPETDFFGRPIQRQQSAPALEAQPAEHDAIEHQMGKAVGRSDVWFRFNEGVSNAVRRNLYIRDLL", "length": 990, "header": "tr|A0A8V0Z6W8-1|A0A8V0Z6W8_CHICK Isoform 1 of Chromosome transmission fidelity protein 18 homolog OS=Gallus gallus OX=9031 GN=CHTF18 PE=3 SV=1 CANONICAL=A0A8V0Z6W8-1" }, "locus": { "chromosome": "14", "start_pos": 5995276, "end_pos": 5984235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044770.1", "url": "https://www.ensembl.org/id/ENSGALT00010044770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026692.1", "url": "https://www.ensembl.org/id/ENSGALP00010026692.1" } ] } }, { "isoform_ac": "A0A8V0ZDR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8/entry#A0A8V0ZDR8-1", "sequence": { "sequence": "MESPGDEDDFTERFAAELEVLAELEDYPSSPGPRVSQFRSRKQLQDEAGPAVGPNAKKRSQECALHPSPPPSPPAGSPMALTPKPKRQRLEAVKKLNFGGDGELAPDVFQDAVTPVPGSASPRGPHAARSQAFPSPELEVSGLGPLQSSPPTENPKRVLRRPPILGDYINVTSSEGTRVFMAVRDDSSHIGIELRDSVGWNRPLHLLGVPFSYLKEQVYEEHRRRAVEVSQQLTETINSCSETSDEATEQPGDTGEEEPTPHCLWVDKFAPRRYIELLSDDYTNRCLLKWLKLWDTVVFGKEKPVKKAKPGAEAHPPFRQHKEQQNKWKTKAQLTEEILEAELDQHKRPKYKVALLCGPPGLGKTTLAHVIARHAGYNVVEMNASDDRSPETFRIRIEAATQMKSVLGAEEKPNCLIIDEIDGAPTASITVLLNIINSKEPEGEAAASGGRRRRREGSLLLRPVICICNDQYVPALRPLRQQAFLLSFPQTAPSRLAQRLGEVWSSPSTTPCMAARAGAVLSSLLPQIAQQQGMRADMGALLALCKKAENDIRSCINTLQFLHSRGQKELDVRVVQTMKIGLKDQNKGLFSIWQEIFQLPRVQRHHIGMDPSLPNHLLADEDEMSHLGVRTALTASSHRFHRVLHLASSSGEQEKLAQGLYENFLNMKLRDSSFSSVCLALEWLCFSDMLGRAVLHGQSFQLMRYLPFLPVAFHMLFAATSIPRLSYPSSHHEALAKLNHMQNLMVSMVSGITPSARSRAGQQSLVLEVLCLLLDIIAPKLRPVNTQLYSLKEKQQLAALISTMLAYNLTYHQERLPEGQYVYKLDPNVEDVCRFPDLPARKQLTYQAKQLIAHEIEMEKMRRTEAVLQARNLNEEPMEMGDVEMKAGGPPVPHNHQQRLEHIVRRAAVRDKPETDFFGRPIQRQQSAPALEAQPAEHDAIEHQMGKAVGRSDVWFRFNEGVSNAVRRNLYIRDLL", "length": 976, "header": "tr|A0A8V0ZDR8-1|A0A8V0ZDR8_CHICK Computationally mapped isoform of Chromosome transmission fidelity factor 18 OS=Gallus gallus OX=9031 GN=CHTF18 PE=3 SV=1 CANONICAL=A0A8V0Z6W8-1" }, "locus": { "chromosome": "14", "start_pos": 5995276, "end_pos": 5984235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044773.1", "url": "https://www.ensembl.org/id/ENSGALT00010044773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026695.1", "url": "https://www.ensembl.org/id/ENSGALP00010026695.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416531", "resource": "KEGG Pathway" }, { "id": "R-GGA-174411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174411", "resource": "Reactome", "description": "Polymerase switching on the C-strand of the telomere" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QF60-1", "protein_name": "Chromosome transmission fidelity protein 18 homolog", "gene_name": "chtf18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEYDEMYGIEDDFERQFADELEVMAELESNNPPAAKVSEFRNKPITQTFEEALVSGDQPSRKSVNNQNPESISPPVYEEEEESLTPKPKKRRQDVAKKLQFGVDQDDDITPPSSPEVYDREVRDGPRFSLTLSPDRPAATKITTNVLDISGLGALQESPKQVTAAKRHAQKRPPAIGDYITVTDSMGNRVYLNKKEDVEKTPDPRAFRNSLNGLGLLAVPIEVLKEQIAERRHRQVVEESQRLTELMKSGIDSDLLAEEQTDSGVDGDSGEDEASSRLWVDQFSPQHYTDLLSDDFTNRCLLKWLKLWDTVVFGRERKSRPVPVEARSNFTNAQNQNQAQRFKTKSQMTEEILEAELDQYKRPKFKVALLSGPPGLGKTTLAHIIAKHAGYNVVEINASDDRSAELFQKRIDTATQMKSVLGANEKPNCLIIDEIDGAPAAAINILLATLNRKDSKDGEETGVNALKKKKKKQSVLLRPIICICNDLYVPALRPLRQQAFLLVFPQTLPSRLAQRLAEISRRQGMKADTGTLMALCEKTDNDIRSCINTLQFLHSRGQKHLDQRSVSSMCVGLKDQNKGLFSVWQEIFQLPRLKRKRIGGDPFSGYDELGPKEGAQRLQHILHLVSSTGEHEKLTQGLYDNFLSMKLKDPGMLGVCSGLDWLCFSDLLNECVLHGQNYSLMRYFPFLPAAFHQLYAATSVPRINYPHSHYEAFTKTQHIRNALLAMLNDIPPAIQSRVCMSSLCLDILSLLLELISPKLRPVNPQLYSTREKQQLYDLIDTMINYNLTYRQDRTPEGQYTYVLEPNIEDVVNYPGLPPRRQLTYQVKQLIARETELERMRRVERAQQSRNPQKMETVNKNQEEKKTEVKKQTSRNHQQRLENIVKQTVVETRPELDFFGRAIVPKEKPVVTATSEDGKVSGVLNIGKAVGNSDVWFRFNEGVSNAVRRNVYIRELL", "length": 957 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HBV4-1", "protein_name": "Chromosome transmission fidelity protein 18 homolog", "gene_name": "Chtf18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDYEEDLYGVEDDFHNQFAAELEVLAELEAGTQDLASSGNLQTPASRPPLTFEEAIAGGDTAPRPCPVGSPENDCRNTRKNVRRDQPGPSSPMIKRPRLEVVKRLNFEPDTEELLYPDSPPGDITPPPSPEVFPEILDPGPSDDSADKGTMQALPSPRNPVLRRPPVLEDYINVTSTSGERAFLVLRADLTGTGVQNPPLDVQWRGHGQLGLLGVPFASLKEQVDNMRRQQLLEEAQELSDTLHSLRSERVDALLEGTPEEDPAPGQHTTQHCLWVDAFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPARKARPSIEPTRIGKEATAPGKWKSHEQVLEEMLEDELDPSRRPRHKVAMLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGAGGRPNCLVIDEIDGASTAAINVLLSVLNRKGPQEAEQGDTAAPAGGRRRRAEGGLLTRPIICICNDQFTPSLRQLKQQAFLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALAALCEKTDNDIRACINTLQFLYGRGRRELSVRDVQTTHVGLKDQRKGLFSVWQEVFQLPKAQRRVVGQDLILPTHALLLNDGDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLHLRLRDSSLGTVCCALDWLAFDDLLEQAAHHGQSFQLLRYLPFLPAAFHVLFASSHVPRITFPSSQQEAQTRMSQTKNHIQTLVSGMAPSTRSRATPQALVLDTLCLLLDVLAPKLRPVSTQLYSAREKQQLSSLVGTMLAYSLTYHQERTPDGQYLYRLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMRRAEALALARGGPQVDQGPSGPASLQTDSGDKGVRQPAPRNHEQRLEHIMKKAVVQEQPERDFFGRVVIRRVAVPSREAEAPEKDTDEWRMGVAVGRSEVWFRFNEGVSNAVRRSLYIRDLL", "length": 968 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P49956-1", "protein_name": "Chromosome transmission fidelity protein 18", "gene_name": "CTF18", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVDTAPYIGSLGRSSLFDTGDIEQAPGNNAIGINEEDIHAFVSSTGETVQLKKKPAKLATGNISLYTNPDTVWRSDDTYGININYLLDKIEASGDDRTNAQKTSPITGKIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLPKLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMVKEKIYNLLFNHTFDTNPVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDSRDSSASDKPACAKNTWASSNKDSPISWFKIVNQLFRKDPHRDIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSDNGIRKPANISDWLFFHDLMYQSMYAHNGELLRYSALVPLVFFQTFGDIANKDDIRMKNSEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKIRNLKLKQAIMEELVQLLKSFQLNLIQNRSEGFDVRGGLTIDPPIDEVVLLNPKHINEVQHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQEMHSKKVKTGLNSSSSTIDFFKNQYGLLKQTQELEETQKTIGSDETNQADDCNQTVKIWVKYNEGFSNAVRKNVTWNNLWE", "length": 741 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8BIW9-1", "protein_name": "Chromosome transmission fidelity protein 18 homolog", "gene_name": "Chtf18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDYEEDLYGVEDDFQNQFAAELEVLAELEGTRDQAPPGTLQTPASRPPLTFEEAIAGGDTVPRPCPAGSPGNVNRNTRKNVRRDQPAPSSPMVKRPRLDVVKKLNFEPDMEELLYPDSPPGDITPPPSPEVFPEMLDAGYSDANADKDLMQTLPSPRNRNPVLRRPPILEDYINVTSTSGERAFLVLRADLIGPGVQNPLLDVHWRGCGQLDLLGVPFASLKEQVDSKRRQQLLEDAQQLSDTLHSLRSEGEEAVLEGPPAEEPAPGQNTAQHCLWVDEFAPQHYTELLSDDFTNRCLLKWLKLWDLVVFGRERPARKPRPGVETTRVGKEATAPGKWKSHEQALEEMLEAELDPSQRPRQKVALLCGPPGLGKTTLAHVVARHAGYCVVEMNASDDRSPEAFRTRIEAATQMESVLGVGGRPNCLVIDEIDGAPTAAINVLLGILNRKGPQEADQGGTAVAAGGRRRRAEGGLLTRPIICICNDQFTPSLRQLKQQALLLHVPPTLPSRLVQRLQEISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYGRGRRELSVKAVQTTHVGLKDQRKGLFSVWQEVFQLPRTQRRIVGQDLMLPAHALLLSNGDKGSLTLASQRFYHILRVTTSAGEHEKVVQGLFDNFLRLRLRDSSLSTVCCALDWLAFDDLLEQAAHRGQSFQLLCYLPFVPAAFHVLFASSHVPRITFPSSQQEAQTRMSQTRNHIQTLVSGMAPTTRSRATPQALVLDTLCLLLDVLAPKLRPVSTQLYSAHEKQQLSCLVGTMLAYSLTYHQERTPDGQYLYKLEPNVEEVCRFPELPARKPLTYQAKQLIAREIEMEKMRRAEALAWARSGPQVDQGSSGPASLWTDSGEKGTRQPAPRNHEQRLEHIMKRATVQEQPERDFFGRVVIRKVAVPSREVEAPQKDADEWRMGVAVGRSEVWFRFNEGVSNAVRRSLYIRDLL", "length": 969 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IQ05-1", "protein_name": "Chromosome transmission fidelity protein 18 homolog", "gene_name": "cutlet", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQYPDENEEFELQYQDELELLEDLPDEFNAYDGPSTSKQAAEKQKENRAPVAALRDSTRLGNSTLGSPQLSQITFGASQLGGEEEAEGTSSGGQVNRRLFGTPKGPPVGRGCSTPFQRMPAIQELENTQLTSRSYGLEKENAAANQLQEVGLKNVNKRRLERDLFGDIDDLFHESYEDPMVKKARTEEQRDHEAIERILELRRKMRESSKTLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYVRFHSEDYEQRQLDLISARGEVVGSLLGEAKDKIWQEAGEIVLSRATAAEDADVTLVNSNANSEPGRLWVDKYKPRKYIDLLSDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEAVTGEGGTAGGAANQLNSFNKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREINASDDRSPEAFKLALENGTQMSSVLNEDKRPNCIVLDEIDGAPRQSIDYLVKFISDAVYTKVKAKGAKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPIDAARLAERLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCISSMQFFNAQKHSLTLQDVLNNNLGQKDRHQGLFAVWDAIFRIQRPRKTLHTDANKVDEPAQVTMTNTSVTTRVRNVLEVVHSSGDYERLTQGVYENYLQQKMPDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLLFATLAWPKIAFPTRGFEFQQKSTNQRNIFQALCKGVTTSALGVGQGGTLLLDTVPLLKRILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGLTFVQVKSQEGHYVFQTEPDLDALSAFPGYTGLSLPYFSRQLIAREVDLERIRRAAPKGGAPSAPAAKKKTSGAAAQLPNHLQTLKPKPISASNMHSAPKQQLTKDFFGRITHKSTSTNSAEESKTDAIVKSPIWYRYKEGFNNAVRKDVHIHELL", "length": 993 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8WVB6-1", "protein_name": "Chromosome transmission fidelity protein 18 homolog", "gene_name": "CHTF18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDYEQELCGVEDDFHNQFAAELEVLAELEGASTPSPSGVPLFTAGRPPRTFEEALARGDAASSPAPAASVGSSQGGARKRQVDADLQPAGSLPHAPRIKRPRLQVVKRLNFRSEEMEEPPPPDSSPTDITPPPSPEDLAELWGHGVSEAAADVGLTRASPAARNPVLRRPPILEDYVHVTSTEGVRAYLVLRADPMAPGVQGSLLHVPWRGGGQLDLLGVSLASLKKQVDGERRERLLQEAQKLSDTLHSLRSGEEEAAQPLGAPEEEPTDGQDASSHCLWVDEFAPRHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPSRKPRPSVEPARVSKEATAPGKWKSHEQVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEMNASDDRSPEVFRTRIEAATQMESVLGAGGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTLQFLYSRGQRELSVRDVQATRVGLKDQRRGLFSVWQEVFQLPRAQRRRVGQDPALPADTLLLGDGDAGSLTSASQRFYRVLHAAASAGEHEKVVQGLFDNFLRLRLRDSSLGAVCVALDWLAFDDLLAGAAHHSQSFQLLRYPPFLPVAFHVLFASSHTPRITFPSSQQEAQNRMSQMRNLIQTLVSGIAPATRSRATPQALLLDALCLLLDILAPKLRPVSTQLYSTREKQQLASLVGTMLAYSLTYRQERTPDGQYIYRLEPNVEELCRFPELPARKPLTYQTKQLIAREIEVEKMRRAEASARVENSPQVDGSPPGLEGLLGGIGEKGVHRPAPRNHEQRLEHIMRRAAREEQPEKDFFGRVVVRSTAVPSAGDTAPEQDSVERRMGTAVGRSEVWFRFNEGVSNAVRRSLYIRDLL", "length": 975 }, "evidence": [ { "id": "A0A8V0Z6W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "DNA clamp loader activity", "id": "GO:0003689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" }, { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W8" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 489, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 783, "end_pos": 785 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6I0-1", "uniprot_ac": "A0A8V0Z6I0", "uniprot_id": "A0A8V0Z6I0_CHICK", "mass": { "chemical_mass": 176221.0, "monoisotopic_mass": 176221.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RRM domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0", "locus": {} } ], "crossref": [ { "id": "cd12716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0G5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSPRGALPQRPRGPNPSGAKPPGPFQGGGVTGPQRAPAPGAPRGAAPRASGQDSVPWTGSQRINVRVTLHRADPRQAKAKSNLHQEQKGDVRAGRWDGSPCPPPPVVSQKPPARLPEQKAAAQNRYTPESASSILASFGLSNEDLEELSRYPDDQLTPENMPLILREIRMRKMGHPLPGLHSQSRGEAMSGTSGAAVKGKVIDYGHASKYGYTEDPLEVPRPYNPEAPSAEKREEFQREQSVPMGVPPAGVACGPAFPPQDVMKPPPAFQSDPANPPPFFPPVVPPLISQPVVPILPQPPFSAELLAILEQRDRIQHEAGSSQPSAPSSGMGQKPFQPQPEGPVKSPFGVVKASWLPSFLQSDSQKIKRLPTPSMMNDYYATSPRIFPHMCSLCNVECARMKVSVFKDYCHSCTQLLTRCSVRPRPAGSSYAPRHSRSRSRSPGRYRPSRPRSRSPRQVRRLSPRHWSRSPQRSRNPLRGSPLAAATWKVLIFGVVFNVQLLREELLNCGTVLQISNLPDDGFSDQDIKKIVQPFGKVSDLIVLKVPLFQAYLEMNYKEAVIAAVKYGETAPVLVNGKQVKISVAEKPKASPSKKEKTKKPVGTKEGKPKMTSDTAGHSVILWVSMGISVSQWRIYGVSMSRCGDPWVPMGVPMCPCGGSVCPYVSLGSPAHSRGLELNEHCGPLQFRPSYDPMGLSVSLWGICGSLCPCGGSVCPYVSLGSPAHRRGLEPDDHCDPFQPRPLYGSSPQSALSCFACCLSSSSHPGWRRSSASCLCLQEADDVCVVLVSNLPDKGYSVEEVSNLAKPFGGLRDVLIVSSHKKAYLEINSRSAESMVKFYTCFPMTLDGNQLCIAMAPQHRSVRDEEAIFTALIKDSDPKVNPETVQQQFVHLGNLPEEGYREFEVVCVGLRFGKVDHYVVLKNRNKAILQLESPKAARSMYCFLNQYSYTMGEHTLTCTLSPSRQQADVSFLFSLLPHCCELPGGAAGRADPAPAGTAAPPTAGRTWGAAPKAVPADVASSAVPPRNPKADAAQKSRVNDSVKTEREQQRVPTAELKAEFEAGADGGVEAEVSGGTAAEESCPLPPVQTAAEVERKRERCGAEVGAAGENAAKNGKERTGSLIRAPQSKESRPATTKGAGAAAASDAPSSIKEPSSAAKVVLKAVVSVPDILKPRVAVQRSKPALCKGEERAAPSKARPQGAAAGQRKAALKEEAQPSSSGKAGGGRNASQQQKDSQGEPRAASKQWQDGESRWSGTKKDGSRWVAARCRSVLHPRCSPSQEEELFPFNLDEFVTVDEVMEESESPVKPQRGQPKGKRKECCRCGSEPGSKRRKERSPPQRLADSQLSFVMLDEIGEEEEGEEEGEAGARLGMLVVDEGGRRRRRRFARADFEEGPKQKEEEEEEEGGAEEPCPVPDDPSALVTVDEIHEDNEDGAAAAWEEANDDEDDFLADFNRLKEELNFVTVDEVGEEDEEEESAPPGRNPKEGNRGEETAAEGAEGRTAAGLSPCPAGGRFCRPCGRIPPCSFQMGLRRLSLHCWQPVLHRRDGDGFLLHHAGLHRRMSSCRLHPSRSLRVSLQATAKGSKQKTEEIKHRIIRNTVSRDLSTPTAHCAHTAFGSLTSQR", "length": 1625, "header": "tr|A0A8V0Z6I0-1|A0A8V0Z6I0_CHICK Isoform 1 of RRM domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6I0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0/entry#A0A8V0Z0G5-1", "sequence": { "sequence": "WWTRWWRRRSRRPRWAKSRPRGGGGGGGALRGRTSKPEPLVTVDEIGEVEELPLNEPTELSAEEGPKQKEEEEEEEGGAEEPCPVPDDPSALVTVDEIHEDNEDGAAAAWEEANDDEDDFLADFNRLKEELNFVTVDEVGEEDEEEESAPPGRNPKEGNRGEETAAEGAEGRTAAGAREEEEDVVGVAGPEEVEVPGGQRPHGDGAAAAGPKGLDFLLPKAGFFCHICSLFYSDES", "length": 236, "header": "tr|A0A8V0Z0G5-1|A0A8V0Z6I0_CHICK Computationally mapped isoform of RRM domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6I0-1" }, "locus": { "chromosome": "4", "start_pos": 90436501, "end_pos": 90430902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044807.1", "url": "https://www.ensembl.org/id/ENSGALT00010044807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026729.1", "url": "https://www.ensembl.org/id/ENSGALP00010026729.1" } ] } }, { "isoform_ac": "A0A8V0Z6I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0/entry#A0A8V0Z6I0-1", "sequence": { "sequence": "MFSPRGALPQRPRGPNPSGAKPPGPFQGGGVTGPQRAPAPGAPRGAAPRASGQDSVPWTGSQRINVRVTLHRADPRQAKAKSNLHQEQKGDVRAGRWDGSPCPPPPVVSQKPPARLPEQKAAAQNRYTPESASSILASFGLSNEDLEELSRYPDDQLTPENMPLILREIRMRKMGHPLPGLHSQSRGEAMSGTSGAAVKGKVIDYGHASKYGYTEDPLEVPRPYNPEAPSAEKREEFQREQSVPMGVPPAGVACGPAFPPQDVMKPPPAFQSDPANPPPFFPPVVPPLISQPVVPILPQPPFSAELLAILEQRDRIQHEAGSSQPSAPSSGMGQKPFQPQPEGPVKSPFGVVKASWLPSFLQSDSQKIKRLPTPSMMNDYYATSPRIFPHMCSLCNVECARMKVSVFKDYCHSCTQLLTRCSVRPRPAGSSYAPRHSRSRSRSPGRYRPSRPRSRSPRQVRRLSPRHWSRSPQRSRNPLRGSPLAAATWKVLIFGVVFNVQLLREELLNCGTVLQISNLPDDGFSDQDIKKIVQPFGKVSDLIVLKVPLFQAYLEMNYKEAVIAAVKYGETAPVLVNGKQVKISVAEKPKASPSKKEKTKKPVGTKEGKPKMTSDTAGHSVILWVSMGISVSQWRIYGVSMSRCGDPWVPMGVPMCPCGGSVCPYVSLGSPAHSRGLELNEHCGPLQFRPSYDPMGLSVSLWGICGSLCPCGGSVCPYVSLGSPAHRRGLEPDDHCDPFQPRPLYGSSPQSALSCFACCLSSSSHPGWRRSSASCLCLQEADDVCVVLVSNLPDKGYSVEEVSNLAKPFGGLRDVLIVSSHKKAYLEINSRSAESMVKFYTCFPMTLDGNQLCIAMAPQHRSVRDEEAIFTALIKDSDPKVNPETVQQQFVHLGNLPEEGYREFEVVCVGLRFGKVDHYVVLKNRNKAILQLESPKAARSMYCFLNQYSYTMGEHTLTCTLSPSRQQADVSFLFSLLPHCCELPGGAAGRADPAPAGTAAPPTAGRTWGAAPKAVPADVASSAVPPRNPKADAAQKSRVNDSVKTEREQQRVPTAELKAEFEAGADGGVEAEVSGGTAAEESCPLPPVQTAAEVERKRERCGAEVGAAGENAAKNGKERTGSLIRAPQSKESRPATTKGAGAAAASDAPSSIKEPSSAAKVVLKAVVSVPDILKPRVAVQRSKPALCKGEERAAPSKARPQGAAAGQRKAALKEEAQPSSSGKAGGGRNASQQQKDSQGEPRAASKQWQDGESRWSGTKKDGSRWVAARCRSVLHPRCSPSQEEELFPFNLDEFVTVDEVMEESESPVKPQRGQPKGKRKECCRCGSEPGSKRRKERSPPQRLADSQLSFVMLDEIGEEEEGEEEGEAGARLGMLVVDEGGRRRRRRFARADFEEGPKQKEEEEEEEGGAEEPCPVPDDPSALVTVDEIHEDNEDGAAAAWEEANDDEDDFLADFNRLKEELNFVTVDEVGEEDEEEESAPPGRNPKEGNRGEETAAEGAEGRTAAGLSPCPAGGRFCRPCGRIPPCSFQMGLRRLSLHCWQPVLHRRDGDGFLLHHAGLHRRMSSCRLHPSRSLRVSLQATAKGSKQKTEEIKHRIIRNTVSRDLSTPTAHCAHTAFGSLTSQR", "length": 1625, "header": "tr|A0A8V0Z6I0-1|A0A8V0Z6I0_CHICK Isoform 1 of RRM domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6I0-1" }, "locus": { "chromosome": "4", "start_pos": 90432074, "end_pos": 90403922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044829.1", "url": "https://www.ensembl.org/id/ENSGALT00010044829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026751.1", "url": "https://www.ensembl.org/id/ENSGALP00010026751.1" } ] } }, { "isoform_ac": "A0A8V0ZDY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0/entry#A0A8V0ZDY0-1", "sequence": { "sequence": "MFSPRGALPQRPRGPNPSGAKPPGPFQGGGVTGPQRAPAPGAPRGAAPRASGQDSVPWTGSQRINVRVTLHRADPRQAKAKSNLHQEQKGDVRAGRWDGSPCPPPPVVSQKPPARLPEQKAAAQNRYTPESASSILASFGLSNEDLEELSRYPDDQLTPENMPLILREIRMRKMGHPLPGLHSQSRGEAMSGTSGAAVKGKVIDYGHASKYGYTEDPLEVPRPYNPEAPSAEKREEFQREQSVPMGVPPAGVACGPAFPPQDVMKPPPAFQSDPANPPPFFPPVVPPLISQPVVPILPQPPFSAELLAILEQRDRIQHEAGSSQPSAPSSGMGQKPFQPQPEGPVKSPFGVVKASWLPSFLQSDSQKIKRLPTPSMMNDYYATSPRIFPHMCSLCNVECARMKVSVFKDYCHSCTQLLTQLTISLSSFRNAADRKENQTPKHRSNSASPGPRRPRPAGSSYAPRHSRSRSRSPGRYRPSRPRSRSPRQVRRLSPRHWSRSPQRSRNPLRGSPLAAATWKVLIFGVVFNVQLLREELLNCGTVLQISNLPDDGFSDQDIKKIVQPFGKVSDLIVPLFQAYLEMNYKEAVIAAVKYGETAPVLVNGKQVKISVAEKPKASPSQVSGVLLSTVPSYDPMGLSVSLWGICGSLCPCGGSVCPYVSLGSPAHRRGLEPDDHCDPFQPRPLYGSSPQSALSCFACCLSSSSHPGWRRSSASCLCLQEADDVCVVLVSNLPDKGYSVEEVSNLAKPFGGLRDVLIVSSHKKAYLEINSRSAESMVKFYTCFPMTLDGNQLCIAMAPQHRSVRDEEAIFTALIKDSDPKVNPETVQQQFVHLGNLPEEGYREFEVVCVGLRFGKVDHYVVLKNRNKAILQLESPKAARSMYCFLNQYSYTMGEHTLTCTLSPKVSADCISYYSVFDFFCFLFTTFSCGLKRYPEGSGGVQSAAAHPPVEPGVVKKEPISIPPVKDGLPAVKAEPSEPHLEGARRDSAAGPAEPTPSRAGAELSRAPIGSAGAEPPAAKPEEKLLPPPCAGKEGLNPEGLDFLLPKAGFFCHICSLFYSDERPYGGPSHCF", "length": 1072, "header": "tr|A0A8V0ZDY0-1|A0A8V0ZDY0_CHICK Computationally mapped isoform of RRM domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6I0-1" }, "locus": { "chromosome": "4", "start_pos": 90437456, "end_pos": 90403922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044838.1", "url": "https://www.ensembl.org/id/ENSGALT00010044838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026760.1", "url": "https://www.ensembl.org/id/ENSGALP00010026760.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1003, "start_aa": "Thr", "end_pos": 1003, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1003", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1040, "end_pos": 1042, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1229, "end_pos": 1231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 512, "end_pos": 588, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1003 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1040, "end_pos": 1042 }, { "start_pos": 1229, "end_pos": 1231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z600-1", "uniprot_ac": "A0A8V0Z600", "uniprot_id": "A0A8V0Z600_CHICK", "mass": { "chemical_mass": 113905.0, "monoisotopic_mass": 113905.0 }, "refseq": { "ac": "XP_414607", "name": "mastermind-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414607" }, "gene_names": [ { "name": "MAML1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ] }, { "name": "MAML1", "type": "synonym", "evidence": [ { "id": "XP_414607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414607" } ] } ], "protein_names": [ { "name": "Mastermind like transcriptional coactivator 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600/entry#names_and_taxonomy" } ] }, { "name": "mastermind-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_414607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414607" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_414607.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414607" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAML1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600", "locus": { "chromosome": "13", "start_pos": 13120369, "end_pos": 13139714, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016964", "url": "https://www.ensembl.org/id/ENSGALG00010016964" } ] } } ], "crossref": [ { "id": "A0A8V0Z600", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z600", "database": "AlphaFoldDB", "categories": [] }, { "id": "416286", "url": "https://www.ncbi.nlm.nih.gov/gene/416286", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PCMITGT", "url": "https://omabrowser.org/oma/group/PCMITGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0I8", "url": "https://www.orthodb.org/?gene=A0A8V0Z0I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z600", "url": "https://www.orthodb.org/?gene=A0A8V0Z600", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15692:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15692:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09596", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09596", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2122947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2122947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2197563", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2197563", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8941856", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z600-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLPPCPMAEFVVPRHSAVMERLRRRIELCRRHHSACESRYQAVSPERLELERQQTFALHQRCLQAKAKRAGKHRQPPPAPPPPAPPPPAAAVAGSAERSGANGLDGEAASGEQHGRSSTLIAQLHETVKRKLDSASSPQNGDQQNGFGDVFSVSKKLRRDDGLGGVSGSSNGMPPVSPLHHLDKKSGSGDTLQLNGKHPMGLDGISKKCLPDSSLQLNGGGDADDSFPLSLNKELKQEPVDDLPCMIAGAGGSISQNNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDADSSNSAAQTPLPQDINIKTEFSPAPFEQEQMGSPQVRSTSSGSAFIGAASVPVSATSPVVGSSQAMFQPSSQSMTENANQPMMQASNHSQNVQRPLPNVLLPGKGAGSAKEMSSAHQLQQIAAKQKRDQMLQNQQQASQVHQTNQMSTWQSGPSHSPLAVPYTMENPTSPSVYQPDFNNQKLMMPNMGNKSSPRAGGNYHVNILGHQQNSMNQNPVNSQGSMLDYGNTKPLSHYKAECEQGVAVPGQNKTPMLAYIQQRQQQPLSHVSDDQNGMILLKPKSGNITYRLPHSQDQTASPNVPRVPVSVPGAGVGAQAPNVTMAGNHSNQSYLSNQQQAAVMKQHQMLMDQQKQREQQQKHLLMEQQKQQFLMEQRQQHLLVEQEKQRQQQEQQLQRHLTRPPPQYQDQQQNPYQQQVGQFTGSSSAMPGVSNLGQSSSSSPRMFPQTQNMIQMGPGHSSVAPLQSSSSQQDRGVTQYANMQNIQRGGLYSIPSGMVPQHAAQSATGQPPMQRQGSLGQGAAVPAGYGQNTLANSSISQQHNKGALNPTLSKPQMARVPAAMGAQNPSWQHQGIPNINNQTQGNSGLGPFSASSSFHMQQTHLKMANQQFAQGMPQVSLSTSRPMTSMNAAVSGQMLSSSLGTQQRTNPPTQQQVPSQQVLPGINQTVPDLNAFNQNPNQQMPNRGNMHCSQGYPVRTSSQELPFAYSSQSGNNGLQNLTGDTDLIDSLLKNRTSEEWMNDLDELLGTH", "length": 1048, "header": "tr|A0A8V0Z600-1|A0A8V0Z600_CHICK Isoform 1 of Mastermind like transcriptional coactivator 1 OS=Gallus gallus OX=9031 GN=MAML1 PE=3 SV=1 CANONICAL=A0A8V0Z600-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600/entry#A0A8V0Z0I8-1", "sequence": { "sequence": "MVLPPCPMAEFVVPRHSAVMERLRRRIELCRRHHSACESRYQAVGANGLDGEAASGEQHGRSSTLIAQLHETVKRKLDSASSPQNGDQQNGFGDVFSVSKKLRRDDGLGGVSGSSNGMPPVSPLHHLDKKSGSGDTLQLNGKHPMGLDGISKKCLPDSSLQLNGGGDADDSFPLSLNKELKQEPVDDLPCMIAGAGGSISQNNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDADSSNSAAQTPLPQDINIKTEFSPAPFEQEQMGSPQVRSTSSGSAFIGAASVPVSATSPVVGSSQAMFQPSSQSMTENANQPMMQASNHSQNVQRPLPNVLLPGKGAGSAKEMSSAHQLQQIAAKQKRDQMLQNQQQASQVHQTNQMSTWQSGPSHSPLAVPYTMENPTSPSVYQPDFNNQKLMMPNMGNKSSPRAGGNYHVNILGHQQNSMNQNPVNSQGSMLDYGNTKPLSHYKAECEQGVAVPGQNKTPMLAYIQQRQQQPLSHVSDDQNGMILLKPKSGNITYRLPHSQDQTASPNVPRVPVSVPGAGVGAQAPNVTMAGNHSNQSYLSNQQQAAVMKQHQMLMDQQKQREQQQKHLLMEQQKQQFLMEQRQQHLLVEQEKQRQQQEQQLQRHLTRPPPQYQDQQQNPYQQQVGQFTGSSSAMPGVSNLGQSSSSSPRMFPQTQNMIQMGPGHSSVAPLQSSSSQQDRGVTQYANMQNIQRGGLYSIPSGMVPQHAAQSATGQPPMQRQGSLGQGAAVPAGYGQNTLANSSISQQHNKGALNPTLSKPQMARVPAAMGAQNPSWQHQGIPNINNQTQGNSGLGPFSASSSFHMQQTHLKMANQQFAQGMPQVSLSTSRPMTSMNAAVSGQMLSSSLGTQQRTNPPTQQQVPSQQVLPGINQTVPDLNAFNQNPNQQMPNRGNMHCSQGYPVRTSSQELPFAYSSQSGNNGLQNLTGDTDLIDSLLKNRTSEEWMNDLDELLGTH", "length": 992, "header": "tr|A0A8V0Z0I8-1|A0A8V0Z600_CHICK Computationally mapped isoform of Mastermind like transcriptional coactivator 1 OS=Gallus gallus OX=9031 GN=MAML1 PE=3 SV=1 CANONICAL=A0A8V0Z600-1" }, "locus": { "chromosome": "13", "start_pos": 13139515, "end_pos": 13121373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040949.1", "url": "https://www.ensembl.org/id/ENSGALT00010040949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023913.1", "url": "https://www.ensembl.org/id/ENSGALP00010023913.1" } ] } }, { "isoform_ac": "A0A8V0Z600-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600/entry#A0A8V0Z600-1", "sequence": { "sequence": "MVLPPCPMAEFVVPRHSAVMERLRRRIELCRRHHSACESRYQAVSPERLELERQQTFALHQRCLQAKAKRAGKHRQPPPAPPPPAPPPPAAAVAGSAERSGANGLDGEAASGEQHGRSSTLIAQLHETVKRKLDSASSPQNGDQQNGFGDVFSVSKKLRRDDGLGGVSGSSNGMPPVSPLHHLDKKSGSGDTLQLNGKHPMGLDGISKKCLPDSSLQLNGGGDADDSFPLSLNKELKQEPVDDLPCMIAGAGGSISQNNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDADSSNSAAQTPLPQDINIKTEFSPAPFEQEQMGSPQVRSTSSGSAFIGAASVPVSATSPVVGSSQAMFQPSSQSMTENANQPMMQASNHSQNVQRPLPNVLLPGKGAGSAKEMSSAHQLQQIAAKQKRDQMLQNQQQASQVHQTNQMSTWQSGPSHSPLAVPYTMENPTSPSVYQPDFNNQKLMMPNMGNKSSPRAGGNYHVNILGHQQNSMNQNPVNSQGSMLDYGNTKPLSHYKAECEQGVAVPGQNKTPMLAYIQQRQQQPLSHVSDDQNGMILLKPKSGNITYRLPHSQDQTASPNVPRVPVSVPGAGVGAQAPNVTMAGNHSNQSYLSNQQQAAVMKQHQMLMDQQKQREQQQKHLLMEQQKQQFLMEQRQQHLLVEQEKQRQQQEQQLQRHLTRPPPQYQDQQQNPYQQQVGQFTGSSSAMPGVSNLGQSSSSSPRMFPQTQNMIQMGPGHSSVAPLQSSSSQQDRGVTQYANMQNIQRGGLYSIPSGMVPQHAAQSATGQPPMQRQGSLGQGAAVPAGYGQNTLANSSISQQHNKGALNPTLSKPQMARVPAAMGAQNPSWQHQGIPNINNQTQGNSGLGPFSASSSFHMQQTHLKMANQQFAQGMPQVSLSTSRPMTSMNAAVSGQMLSSSLGTQQRTNPPTQQQVPSQQVLPGINQTVPDLNAFNQNPNQQMPNRGNMHCSQGYPVRTSSQELPFAYSSQSGNNGLQNLTGDTDLIDSLLKNRTSEEWMNDLDELLGTH", "length": 1048, "header": "tr|A0A8V0Z600-1|A0A8V0Z600_CHICK Isoform 1 of Mastermind like transcriptional coactivator 1 OS=Gallus gallus OX=9031 GN=MAML1 PE=3 SV=1 CANONICAL=A0A8V0Z600-1" }, "locus": { "chromosome": "13", "start_pos": 13139515, "end_pos": 13121373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040952.1", "url": "https://www.ensembl.org/id/ENSGALT00010040952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023916.1", "url": "https://www.ensembl.org/id/ENSGALP00010023916.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2122947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2122947", "resource": "Reactome", "description": "NOTCH1 Intracellular Domain Regulates Transcription" }, { "id": "R-GGA-2197563", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2197563", "resource": "Reactome", "description": "NOTCH2 intracellular domain regulates transcription" }, { "id": "R-GGA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-GGA-8941856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941856", "resource": "Reactome", "description": "RUNX3 regulates NOTCH signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MF28-1", "protein_name": "Mastermind like transcriptional coactivator 1", "gene_name": "MAML1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAPAPAPAPAPAAAPRLDAADGPEHGLPVAHLHDTVKRNLDSATSPQNGDQQNGYGDFFPGHKKTRREASLGAAVSSNGLPPASPLGQPDKPGPEALQATGKHALGLDSISKKCLADSSLHLNGGSNTSESFPLSLNKELKQEPMDDLPCMIAGAGGSISQGNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFMGPSSGPVTTDSPSLGGSQPLFLTAGQPGVDSPSPSLMPASAQAQNAQRALSSVVLPSQGPGGGSELSSAHQLQQIAAKQKREQMLQNPQQAAPTPAPGQMSTWQQTGPAHSPLNAPYPVEKPASPPGYKPDFTTSKLLMMPSVNKSSPRPGGPYLQPSHVSLHQPPSNLNQNPVASQGSVLDYGNTKPLSHYKADCGQGGPGAGQSKPALMAYLPQQLPHLSSEQSSLFLIKPKPGNMPFRSLVAPSQDQNPPNVPVPTQAASVGTQPPAVSVASTHSSTYLSNQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGSSSAMPGVNSLGPSNSSCPRVFPQAGNLMPMGPGHTSVSSLPSNSGQQDRGVAQFTGSQSMPQSSLYGMTSSITQMVPQPPPQATNGHAHIPRQTSVGQNTSVSAAYGQNSLGNSGLSQQHSKGTLNSGLTKPQVPRVSAAMGGQNSTWQHQGMPNLSGQPPGNSAVSPFTAASSFHLQQAHLKMSSPQFSQAMPSRPMAPMSSAAVAGSMLPTVSTQQRTSAPVPAPPQGAPQQGLSGLSPAGPELGAFSQSPAPAMGGRPGLHCAQAYPVRTAGQELPFAYSGQPGSGGLASMAGDADLIDSLLKNRTSEEWMSDLDDLLGPQ", "length": 1013 }, "evidence": [ { "id": "A0A8V0Z600", "url": "https://omabrowser.org/oma/group/A0A8V0Z600/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A930-1", "protein_name": "Mastermind-like transcriptional coactivator 1", "gene_name": "Maml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPAAAPAPAPAPAAARLDSADGPEHGRPVAHLHDPVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPPVGDALQTGGKHSLGLDPINKKCLADSSIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGSSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLAPSSAPVGTDSPSLGNSQTLFHTTGQPGVDSSSPNLMPASAQAQNAPRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQLSTWQQAGPSHSPLDAPYPMEKPASPSGYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNPNPVNNQGSMLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVPAPAASVGTQPSVSVASTHSSSYLSSQQQAAVMKQHQLLLDQQKQREQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFQQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPPSSGQQDRGVAQFTGSQSLPHNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLAKPQVPRVSAAMGSQNPSWQHQGMPNLSSQTPGNSSVSPFTAASSFHRQQAHLKMSAQQFSQAMPTRPMAPLSSAAAAGPMLPSVSTQQRNSAPAPAPPQAASQQGLPGLSPSGPELGAFGQSPTSQMNSRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "length": 1017 }, "evidence": [ { "id": "A0A8V0Z600", "url": "https://omabrowser.org/oma/group/A0A8V0Z600/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S442-1", "protein_name": "Mastermind like transcriptional coactivator 1", "gene_name": "MAML1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAPAPAPAPAPAPRLDVTDGPEHGRPVAHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLGVAVSSNGLPPASPLGQPDKPGTDALQASGKHSLGLDSISKKCLADSSLHPNGGNNPGESFPLSRNKELKQEPVDDLPCMIPGAGGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFMGPSSGPVSTDSASLGGSQPLFHASGQPGVDSPSPNLMPASAQAQNAQRALSSVVLPSQGPAGGSELSSAHQLQQIAAKQKREQMLQNPQQTAPAPGPGQMSTWQQTGPSHSPLNVPYPMEKPASPPSYKQDFSNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLGQNAVASQGSVLDYGNTKPLSHYKADCGQGSPGAGQSKPALMAYLPQQLPHLNNEQNSLFLMKPKPGNMPFRSLVPPSQEQNPPNVPVPTQAASVGTQPPAVSVASTHSSTPYLSNQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGSSAALPGLNNLGPSNSNCPRVFPQAGNLMPMGPGHTSVSSLPSNSGQQDRGVAQFTGSQSMPQSSLYGMASGITQIVTQPPPQATNGHAHIPRQTSVGQNTSVSAAYGQNSLGNSGLSQQHNKGTLNSGLTKPQVPRVSATMGGQNSSWQHQGMPNLSSQTPGNNTVSPFTAASSFHMQQAHLKMSSPQFSQAMPSRPMAPMSSAAAAGSMLPPVSTQQRTSAPAPAPPQGAPQQGLPGLSSAGPELGAFNQSPAPAMGGRAGLHCAQAYPVRTAGQELPFAYSGQPSGSGLASMAGDADLIDSLLKNRTSEEWMNDLDDLLGPQ", "length": 1014 }, "evidence": [ { "id": "A0A8V0Z600", "url": "https://omabrowser.org/oma/group/A0A8V0Z600/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6T264-1", "protein_name": "Mastermind-like protein 1", "gene_name": "Maml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQIVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ", "length": 1020 }, "evidence": [ { "id": "A0A8V0Z600", "url": "https://omabrowser.org/oma/group/A0A8V0Z600/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92585-1", "protein_name": "Mastermind-like protein 1", "gene_name": "MAML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ", "length": 1016 }, "evidence": [ { "id": "A0A8V0Z600", "url": "https://omabrowser.org/oma/group/A0A8V0Z600/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "peptide antigen binding", "id": "GO:0042605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "positive regulation of transcription of Notch receptor target", "id": "GO:0007221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "positive regulation of myotube differentiation", "id": "GO:0010831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010831", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "atrioventricular node cell development", "id": "GO:0060928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060928", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" }, { "name": "MAML1-RBP-Jkappa- ICN1 complex", "id": "GO:0002193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z600", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 964, "end_pos": 966, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z600" }, { "id": "SM01275", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01275" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurogenic mastermind-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 73, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 1031, "end_pos": 1033 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 964, "end_pos": 966 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6R0-1", "uniprot_ac": "A0A8V0Z6R0", "uniprot_id": "A0A8V0Z6R0_CHICK", "mass": { "chemical_mass": 122745.0, "monoisotopic_mass": 122745.0 }, "refseq": { "ac": "NP_001073186", "name": "ubinuclein-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186" }, "gene_names": [ { "name": "UBN1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ] }, { "name": "UBN1", "type": "synonym", "evidence": [ { "id": "NP_001073186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186" } ] }, { "name": "ubinuclein-1", "type": "synonym", "evidence": [ { "id": "NP_001073186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186" } ] } ], "protein_names": [ { "name": "Ubinuclein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#names_and_taxonomy" } ] }, { "name": "ubinuclein-1", "type": "synonym", "evidence": [ { "id": "NP_001073186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001073186.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001073186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0", "locus": { "chromosome": "14", "start_pos": 13266246, "end_pos": 13241011, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018555", "url": "https://www.ensembl.org/id/ENSGALG00010018555" } ] } } ], "crossref": [ { "id": "A0A8V0Z6R0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416398", "url": "https://www.ncbi.nlm.nih.gov/gene/416398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416398", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416398", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHHGLAH", "url": "https://omabrowser.org/oma/group/FHHGLAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0R0", "url": "https://www.orthodb.org/?gene=A0A8V0Z0R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0S1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0T8", "url": "https://www.orthodb.org/?gene=A0A8V0Z0T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6R0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7A9", "url": "https://www.orthodb.org/?gene=A0A8V0Z7A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE21", "url": "https://www.orthodb.org/?gene=A0A8V0ZE21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE25", "url": "https://www.orthodb.org/?gene=A0A8V0ZE25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE32", "url": "https://www.orthodb.org/?gene=A0A8V0ZE32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE50", "url": "https://www.orthodb.org/?gene=A0A8V0ZE50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE56", "url": "https://www.orthodb.org/?gene=A0A8V0ZE56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2559584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001073186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1135, "header": "tr|A0A8V0Z6R0-1|A0A8V0Z6R0_CHICK Isoform 1 of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0Z0R0-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHNASQLHGKGSNAQQRKL", "length": 1105, "header": "tr|A0A8V0Z0R0-1|A0A8V0Z6R0_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044900.1", "url": "https://www.ensembl.org/id/ENSGALT00010044900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026816.1", "url": "https://www.ensembl.org/id/ENSGALP00010026816.1" } ] } }, { "isoform_ac": "A0A8V0Z0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0Z0S1-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1027, "header": "tr|A0A8V0Z0S1-1|A0A8V0Z6R0_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044918.1", "url": "https://www.ensembl.org/id/ENSGALT00010044918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026826.1", "url": "https://www.ensembl.org/id/ENSGALP00010026826.1" } ] } }, { "isoform_ac": "A0A8V0Z0T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0Z0T8-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1092, "header": "tr|A0A8V0Z0T8-1|A0A8V0Z6R0_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044940.1", "url": "https://www.ensembl.org/id/ENSGALT00010044940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026841.1", "url": "https://www.ensembl.org/id/ENSGALP00010026841.1" } ] } }, { "isoform_ac": "A0A8V0Z6R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0Z6R0-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1135, "header": "tr|A0A8V0Z6R0-1|A0A8V0Z6R0_CHICK Isoform 1 of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044928.1", "url": "https://www.ensembl.org/id/ENSGALT00010044928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026833.1", "url": "https://www.ensembl.org/id/ENSGALP00010026833.1" } ] } }, { "isoform_ac": "A0A8V0Z7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0Z7A9-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1103, "header": "tr|A0A8V0Z7A9-1|A0A8V0Z7A9_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=4 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044937.1", "url": "https://www.ensembl.org/id/ENSGALT00010044937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026840.1", "url": "https://www.ensembl.org/id/ENSGALP00010026840.1" } ] } }, { "isoform_ac": "A0A8V0ZE21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0ZE21-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARTLFKESRRVHGHLTSELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPICQLLKLTLFCGTQKEQGNKSESV", "length": 897, "header": "tr|A0A8V0ZE21-1|A0A8V0ZE21_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13260365, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044888.1", "url": "https://www.ensembl.org/id/ENSGALT00010044888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026807.1", "url": "https://www.ensembl.org/id/ENSGALP00010026807.1" } ] } }, { "isoform_ac": "A0A8V0ZE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0ZE25-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPMLLSFTAKGPTHSSGSCDVCQEGS", "length": 1011, "header": "tr|A0A8V0ZE25-1|A0A8V0ZE25_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263881, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044893.1", "url": "https://www.ensembl.org/id/ENSGALT00010044893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026812.1", "url": "https://www.ensembl.org/id/ENSGALP00010026812.1" } ] } }, { "isoform_ac": "A0A8V0ZE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0ZE32-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1075, "header": "tr|A0A8V0ZE32-1|A0A8V0ZE32_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044910.1", "url": "https://www.ensembl.org/id/ENSGALT00010044910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026822.1", "url": "https://www.ensembl.org/id/ENSGALP00010026822.1" } ] } }, { "isoform_ac": "A0A8V0ZE50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0ZE50-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKMLEEEKDKEQRDRVCSDDDEDDEKGGKRVTGPRKKFQWNDEIRELLCHLVKIKLDGYEYDKNKAQSLEDYVKTFLDGEVKPLWPKGWMQARAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1118, "header": "tr|A0A8V0ZE50-1|A0A8V0ZE50_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044934.1", "url": "https://www.ensembl.org/id/ENSGALT00010044934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026837.1", "url": "https://www.ensembl.org/id/ENSGALP00010026837.1" } ] } }, { "isoform_ac": "A0A8V0ZE56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0/entry#A0A8V0ZE56-1", "sequence": { "sequence": "MTEPHRVLFTTLHGPLSSSFLKKPRKDDAEQPPDVEQPGETVRLSLTLFEPDHKRCPEFYYPDLLKNSQAKRKGSSGDKRKEPADPFDDEKERHKAEALARKFEEKYGGKRRRKDRFQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDEYVKEKKKKSPKKRKLKDGGEKMKKRKKDDSYDKEKKSKKSKFPKAGFTALNASKEKKKKKYSGALSVKEMLRKFQKEKEAQKKKDEEQKVVTPSPAEPQVPREAETMPDPLLSLFGHASDSDLLQAATAMDTLTDLDLERLFSESPEGSPLHDVEDGSNPAGAGLEQDFKQLPSLPEGLPAPLEKRIKELAQAARAAEGEGKQKFFTQDINNIILDIELQTRELNSQIRSGVYTHLAAFLPCSKDTLVKRARKLYLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQEECQAHTQAKFVKTLFKESRRVHGHLTSVLAKKKVVAPAKVKGKELSSKPDKKVAVSVPSVHSSNTVALSSESQAGGLNISAQTRELLSLGTAQAANSAATPAAFMDNSLDEDLIHNPTSSLEAVSKELAVLNSRAGGSPDFPLPGAPKAPPEKIPTLASSEEKRTFPKAHPAPTTSSAASLQSPLNFLAEQALALGQSSQDKKAENSNYKELSCQASPSKILPDIHQAKQKHHSLVRPSHGPQTSTSVPGTQVKVFHSSNQPQKAFTSPAPFVKLQNPKSSSPLPQRSLLQQVKSSTKAQSFHSSATSGSTQNSSGSHKSPGSSSSSLNYTGKHSSGSSTSGQSYKSPFVSGSLSKHGASSSSSSSGASANQGCSSGNLLPSMQTPSSSQASGRPAPSSAVKKTPVSQKLTLVAPPGGSNGDSSGGTQGVAKLLTSSLKPAVASSAASSTSVPKGTSGAVLLTSSSSLSVLSPSYKSNNPKLPAALSSTPLGIISPIHTFPLHVISFTSDSTPKAGVSKDAIVTGPAPGTFHHGLGHSLLAGLHSSPHHAAPLPHSALSTHLPQSLPDASQLHGKGSNAQQRKL", "length": 1044, "header": "tr|A0A8V0ZE56-1|A0A8V0ZE56_CHICK Computationally mapped isoform of Ubinuclein 1 OS=Gallus gallus OX=9031 GN=UBN1 PE=3 SV=1 CANONICAL=A0A8V0Z6R0-1" }, "locus": { "chromosome": "14", "start_pos": 13263859, "end_pos": 13241657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044944.1", "url": "https://www.ensembl.org/id/ENSGALT00010044944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026842.1", "url": "https://www.ensembl.org/id/ENSGALP00010026842.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 651, "start_aa": "Thr", "end_pos": 651, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr651", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416398", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416398", "resource": "KEGG Pathway" }, { "id": "R-GGA-2559584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559584", "resource": "Reactome", "description": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A8C6-1", "protein_name": "Ubinuclein 1", "gene_name": "Ubn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEPHRVQFTSLPGSLNPALLKKSRKEEVGGTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNTRGKVKGLHPGDKKKDVLDPFNDEEKERHKVEALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSSVEAQGLRELEGTSDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEQLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSFPEGLPTPLEKRVKELAQAARAAEGDSKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKVKTKESSVKPDKKVSIPSGQHGGPTTLLSEHQGGGLNIGANSREHPSQATCGLTDPVPVTLEDSLDEDLVRNPASSVDAVSKELAVLNSRAANSSEFTLPAPSKAPTEKVAGVLCTEEKRNFTKPSSSAPPPTNALQSPLNFLAEQALALGQSSQEKKPEGSGYKELSCQAPLSKGMPELHQSKAKHHSLQRTSHGPQAAAPVPGPQVKVFHAGTQQQKSFTPPSPFVNKLQGPKATSPQCHRSFLQLVKTAAKGQSFHATMPASSGSSPASSSSSHKTTASNSTTISHPAKLHPASSVGPSYKNNPFAGSISKHGAASSSTSSGGGAQVQSSVSGTLLPGVQPPSAGQPASRTAPSSAVKKTPVTQKLTLVAPPGGPNGDSGGGTQGVAKLLTSSLKPAAVSSVTSSTSLPKGTGGAVLLSNNSSLSLLSSSYKSNTPKLPGTMNSNSLGIITPFPLHVLSFSADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSSPPHTAPLPHAAVSTHVPQSLPDTSQLHGKGPVVPRKL", "length": 1135 }, "evidence": [ { "id": "A0A8V0Z6R0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HS51-1", "protein_name": "Ubinuclein-1 isoform X1", "gene_name": "Ubn1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEPHRVQFTSLPGSLNPAFLKKSRKEEVGGTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLHPGDKKKDVLDPFNDEEKERHKVEALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKESGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSSTEAQGLRELEGTSDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEQLLSESPEGSPFQDMDDESDSLGVGLDQEFRQPSSFPEGLPTPLEKRVKELAQAARAAEGESKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKIKVKESSAKPDKKVSISSGQLGGPTTLLSEHQGGSLNIGATNRELSSQATCGLSDPVPVTLEDSLDEDLVRNPASSVETVSKELAVLNSRAASSSEFTLPAPSKAPTEKVAGVLCTEEKRNFAKPSSSAPPSTNALQSPLNFLAEQALALGQSSQEKKPESSGYKELSCQAALSKGISELHQSKAKHHSLPRTSHGPQAATPMPSSQVKVFHAGTQQQKSFTPPTPFVNKLQGPKAASPQCHRSLLQLVKTAAKGQAFHATMPSSSGTSPASSSSSHKTAASSSTPLSHPAKQHPASSVGPSYKNNPFSGSVSKHGASSSSPSPAGAQVQSSVSGTLLPSVQSPSAGQPSSRAAPSSAVKKTPVSQKLTLVAPPGGPNGDSGGGTQGVAKLLTSSLKPPAVSSVTSSTSLPKGTGGAMLLSNTSSLSLLSSSYKPSNPKLQGAMNSNSLGIITSVPFPLHVLSFSSDSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSSPPHTAPLPHTAVSTHVPQSLPDTSQLHGKGPVVPRKL", "length": 1136 }, "evidence": [ { "id": "A0A8V0Z6R0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6R0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4G0F8-1", "protein_name": "Ubinuclein-1", "gene_name": "Ubn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEPHRVQFTSVPGSLNPAFLKKSRKEEVGGTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLHPGDKKKDVLDPFNDEEKERHKVEALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSSIEAQGLRELEGTSDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEQLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSFPEGLPIPLEKRVKELAQAARAAEGESKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKIKMKESSVKLDKKVSVPSGQHGGPTTLLSEHQGGGLNTGANSREHPSQATCGLTDSVSVTLEDSLDEDLVRNPASSVDAVSKELATLNSRAANSSEFTLPTPSKAPTEKVGGVLCTEEKRNFAKPSSSAPPPTNALQSPLNFLAEQALALGQSSQEKKPEGSGFKELSCQGPLSKGVPELHPSKAKHHNLPRTSHGPQAAAPVPGPQVKVFHAGTQQQKSFTPPSPFVNKLQGPKATSPQCHRSLLQLVKTAAKGQAFHATMPASSGSSPASSSSAHKTTASNSTTISHPAKLHPTSSVGPSYKNNPFAGSVSKHGASSSSPSPGGGAQVQSSVSGASLPGVQSPSAGQSASRAAPSSAVKKTPVTQKLTLVAPPGGPNGDSGGGTQGVAKLLTSSLKPAAVSSVTSSTSLPKGTGGAVLLSNTSSLSLLSSSYKSNNPKLPGAMNSNSLGIITQFPLHVLSFNADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSSPPHTAPLPHAAVSTHVPQSLPDASQLHGKGPVVPRKL", "length": 1135 }, "evidence": [ { "id": "A0A8V0Z6R0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NPG3-1", "protein_name": "Ubinuclein-1", "gene_name": "UBN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEPHRVQFTSLPGSLNPAFLKKSRKEEAGAGEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLQPGDKKKDLSDPFNDEEKERHKVEALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASKEKKKKKYSGALSVKEMLKKFQKEKEAQKKREEEHKPVAVPSAEAQGLRELEGASDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSESPEGSPFRDMDDGSDSLGVGLDQEFRQPSSLPEGLPAPLEKRVKELAQAARAAEGESRQKFFTQDINGILLDIEAQTRELSSQVRSGVYAYLASFLPCSKDALLKRARKLHLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQDECQAHTQAKVAKMLEEEKDKEQRDRICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESQDLERNNKAQAWEDCVKGFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDKKVSVPSGQIGGPIALPSDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAALNSRAAGNSEFTLPAPSKAPAEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLNFLAEQALALGQSSQEKKPESSGYKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVPVPGPQVKVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVSSGSSSSGGTPVQSSVSGSLVPGIQPPSVGQATSRPVPSSAGKKMPVSQKLTLVAPPGGPNGDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGSSLMASPYKSSSPKLSGAMSSNSLGIITPVPIPVHVLSFSADSSAKAGVSKDAIVTGPAPGSFHHGLGHSLLAGLHSSPPHAAPLPHAAVPTHIPQSLPGASQLHGKGPAVPRKL", "length": 1134 }, "evidence": [ { "id": "A0A8V0Z6R0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6R0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" }, { "id": "PF08729", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08729" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hpc2-related", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 163, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z6R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R0" }, { "id": "PF14075", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14075" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubinuclein middle", "eco_id": "ECO_0000259", "start_pos": 348, "end_pos": 567, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 651 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 864, "end_pos": 866 }, { "start_pos": 880, "end_pos": 882 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6T3-1", "uniprot_ac": "A0A8V0Z6T3", "uniprot_id": "A0A8V0Z6T3_CHICK", "mass": { "chemical_mass": 133419.0, "monoisotopic_mass": 133419.0 }, "refseq": { "ac": "NP_001239253", "name": "fibronectin type III domain-containing protein 3B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239253" }, "gene_names": [ { "name": "FNDC3B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" } ] }, { "name": "FNDC3B", "type": "synonym", "evidence": [ { "id": "NP_001239253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239253" } ] } ], "protein_names": [ { "name": "Fibronectin type III domain-containing protein 3B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#names_and_taxonomy" } ] }, { "name": "Factor for adipocyte differentiation 104", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#names_and_taxonomy" } ] }, { "name": "HCV NS5A-binding protein 37", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#names_and_taxonomy" } ] }, { "name": "fibronectin type III domain-containing protein 3B", "type": "synonym", "evidence": [ { "id": "NP_001239253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239253" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.191006.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On or before Dec 16, 2021 this sequence version replaced XP_015147147.2, NP_001239253.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239253" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FNDC3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3", "locus": { "chromosome": "9", "start_pos": 19017755, "end_pos": 19164513, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018579", "url": "https://www.ensembl.org/id/ENSGALG00010018579" } ] } } ], "crossref": [ { "id": "A0A8V0Z6T3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6T3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424984", "url": "https://www.ncbi.nlm.nih.gov/gene/424984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424984", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NACEIAW", "url": "https://omabrowser.org/oma/group/NACEIAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0V5", "url": "https://www.orthodb.org/?gene=A0A8V0Z0V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6T3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6U2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6V2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7E6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001239253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHIVNGDGSQQVFLVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGRESEYKQVYKGDETTFQISGLQVNTDYRFRVCVCRRCSDTSQELSGPFSPSVAFMLQQNEIMLAGEMGRIDDPKIKSMIATDEQFAALIVLGFASLSIIFACILQYFFMK", "length": 1208, "header": "tr|A0A8V0Z6T3-1|A0A8V0Z6T3_CHICK Isoform 1 of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#A0A8V0Z0V5-1", "sequence": { "sequence": "MIMALALLCLYSVPQNGTGMLRAGFQSGNHKLLACTTAFQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGRESEYKQVYKGDETTFQISGLQVNTDYRFRVCVCRRCSDTSQELSGPFSPSVAFMLQQNEIMLAGEMGRIDDPKIKSMIATDEQFAALIVLGFASLSIIFACILQYFFMK", "length": 1186, "header": "tr|A0A8V0Z0V5-1|A0A8V0Z6T3_CHICK Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "locus": { "chromosome": "9", "start_pos": 19100913, "end_pos": 19020307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044966.1", "url": "https://www.ensembl.org/id/ENSGALT00010044966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026857.1", "url": "https://www.ensembl.org/id/ENSGALP00010026857.1" } ] } }, { "isoform_ac": "A0A8V0Z6T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#A0A8V0Z6T3-1", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHIVNGDGSQQVFLVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGRESEYKQVYKGDETTFQISGLQVNTDYRFRVCVCRRCSDTSQELSGPFSPSVAFMLQQNEIMLAGEMGRIDDPKIKSMIATDEQFAALIVLGFASLSIIFACILQYFFMK", "length": 1208, "header": "tr|A0A8V0Z6T3-1|A0A8V0Z6T3_CHICK Isoform 1 of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "locus": { "chromosome": "9", "start_pos": 19139472, "end_pos": 19020307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044973.1", "url": "https://www.ensembl.org/id/ENSGALT00010044973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026859.1", "url": "https://www.ensembl.org/id/ENSGALP00010026859.1" } ] } }, { "isoform_ac": "A0A8V0Z6U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#A0A8V0Z6U2-1", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHIVNGDGSQQVFLVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGRESEYKQVYKGDETTFQISGLQVNTDYRFRVCVCRRCSDTSQELSGPFSPSVAFMLQQNEIMLAGEMGRIDDPKIKSMIATDEQFAALIVLGFASLSIIFACILQYFFMK", "length": 1190, "header": "tr|A0A8V0Z6U2-1|A0A8V0Z6U2_CHICK Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "locus": { "chromosome": "9", "start_pos": 19139472, "end_pos": 19020307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044986.1", "url": "https://www.ensembl.org/id/ENSGALT00010044986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026869.1", "url": "https://www.ensembl.org/id/ENSGALP00010026869.1" } ] } }, { "isoform_ac": "A0A8V0Z6V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#A0A8V0Z6V2-1", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHIVNGDGSQQVFLVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGKAASRSVEKSHL", "length": 1110, "header": "tr|A0A8V0Z6V2-1|A0A8V0Z6V2_CHICK Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "locus": { "chromosome": "9", "start_pos": 19139472, "end_pos": 19017915, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045000.1", "url": "https://www.ensembl.org/id/ENSGALT00010045000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026879.1", "url": "https://www.ensembl.org/id/ENSGALP00010026879.1" } ] } }, { "isoform_ac": "A0A8V0Z7E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3/entry#A0A8V0Z7E6-1", "sequence": { "sequence": "MNVRHNDDDRPNPAGAATAAEWGGSHDASHCEWRRISAGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAISPTHHLPPYLTHHPHFIHNSHTAFYPPVTGPGDMPPQFFPQHHLPPTLYGEQEIIPLYGMSSYITREDQYSKPQHKKLKERQIDRQNRLNSPPSSIYKSHIGSCTTVYNGYAKSHNGASSGSGGGAPGVKKPERRARSSPKSTEQEPHEYDSETKRVQDILSGMEKPQVTNIQARTVLLSWSPPAGLLNTDRHNNGLPYACTYEVALSDKGRDGKYKIIYSGEELEYNLKDLRPATDYHVRVYATYNSVRGSCSEPVSFTTHSSAPECPFPPKPSHRTKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRECYFGSQKHCKLTKLCPALGYTFRLAAQNDIGTSGYSQEVVCYTAGNIPQTPSAPRLVRAGVTWVALQWNKVEGCTPEEVISYTLEIQEEDNDSVFHPKYTGEEQACTVKNLRRSTQYKFRLFASNVEGKSSPSEVLVCTTSPDRPGPPTRPIIKGPITSHGFSVKWDPPQDNGGSEILKYLLEISQGSPEANQWEVAYSGSATEYTCTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSVAPGHCQPPRVLGKPKHKEVQLQWDVPTSESGCPISEYSVEMTEPEEVVSEVYHGPDLECTVSNLLPGATYRFRVRALNDGGYGPYSEATEITTAAGPPGQCRAPSLSFLSDTRVLVSWESPECSGADISEYRLEWGEDEESLQLAYNGTDTCFEISELSAAAQYCCRLQAVNQAGAGPYSELATCRIPASVPDAVSTLFVLEDEHVDACQLSPSVCLALNWEEPGNNGAEITSYNIDLGDISIPIGNVTSYVIHDLLPETSYRIRIQAVNEIGAGPFSHFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSSSKLHATDDMVYILQIEDRNKRFIPIYRGPSHTYKIQRLTESTCYSFRIQAVNDAGEGPFSEICTFCTTKSVPPAIKAPRVMQLEGNACEITWEMVPPMKGDPVGYVLQVLVGRESEYKQVYKGDETTFQISGLQVNTDYRFRVCVCRRCSDTSQELSGPFSPSVAFMLQQNEIMLAGEMGRIDDPKIKSMIATDEQFAALIVLGFASLSIIFACILQYFFMK", "length": 1184, "header": "tr|A0A8V0Z7E6-1|A0A8V0Z7E6_CHICK Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Gallus gallus OX=9031 GN=FNDC3B PE=3 SV=1 CANONICAL=A0A8V0Z6T3-1" }, "locus": { "chromosome": "9", "start_pos": 19139476, "end_pos": 19020307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044996.1", "url": "https://www.ensembl.org/id/ENSGALT00010044996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026876.1", "url": "https://www.ensembl.org/id/ENSGALP00010026876.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424984", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MAR2-1", "protein_name": "Fibronectin type III domain-containing protein 3B", "gene_name": "Fndc3b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQHHLPPTIYSEQEIIPLYGMSSYITREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKSNCATVYNGYGKGHSGGSSGGVGGGSGGGPGSKKSERRARSSPKSSDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGACSEAVSFTTHSCAPECPFPPKLAHRSRSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGNQKHCKMTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGVTWITLQWTRPEGCSPEEVITYTLDIQEDENDSHFHPKYSGEDLTCTVKNLKRSTQYKFRLTASNMEGRSCPSEVLVCTTSPDRPGPPTRPLIKGPVTSHGFSVKWDAPKDSGGSEILKYLLEITDGTSEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTATGPPGQCRAPCISFTPDGCVLVGWESPESPGADISEYRLEWGEDEESLELVYHGPDTCFEIQDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSSLCVLEEEPLDAHLDSPSVCLVLNWEEPCNNGSEIIAYNIDLGDTCITVGNTTTRVIKDLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPLPPRLECAASGPQSLKLKWGDSNSKTHAADDMVFTLQLEDRNKRFVSIYRGPSHTYKVQRLTEFTCYSFRIQASSEAGEGPFSETYTFSTTKSVPPTLKAPRVTQLEGNSCEILWETVPPMKGDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSVAFVLQQREVMLTGDMGSMDDPKMKGMMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207 }, "evidence": [ { "id": "A0A8V0Z6T3", "url": "https://omabrowser.org/oma/group/A0A8V0Z6T3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LL52-1", "protein_name": "Fibronectin type III domain-containing protein 3B", "gene_name": "Fndc3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQPHLPPTIYSEQEIIPLYGMSSYITREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKNSCATMYNGYGKGHSGGSSGGGGGGSGGGPGIKKTERRARSSPKSSDSDLQEYELEVRRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLPCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGGQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDNHFHPRYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLLKGPVTSHGFSVKWDAPKDNGGSEILKYLLEITDGASEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCIGTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKEVHLEWDVPASEGGCEVSEYSVEMTEPEEVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAPCVSFTPDGCVLVGWESPESPGADISEFRLEWGEDEESLELIYHGPDTCFEIRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSTLCVLEEEPLSAHLDSPSVCLVLTWEEPCSNGSEIIAYNIDLGDTCITVGNTTTHVLKNLLPETTYRIRIQAVNDIGDGPFSQFIKAKTRPLPPSPPRLECAASGPQSLKLKWGDSNSKIHAAHDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQATSEAGEGPFSDTYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPMKGDPVNYVLQVLVGRESEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSAAFVLQQREVLLTGDLGGMDDAKMKGVMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207 }, "evidence": [ { "id": "A0A8V0Z6T3", "url": "https://omabrowser.org/oma/group/A0A8V0Z6T3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MPN0-1", "protein_name": "Fibronectin type III domain-containing protein 3B", "gene_name": "FNDC3B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGDAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDNTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIHNSHTAYYPPVTGPGDMPPQFFPQHHLPPTIYSEQEIIPLYGMSSYITREDQYSKPPHKKLKDRQIDRQNRLNSPPSSIYKSNCTTVYNGYGKGHSGGGGGGGGGGSGGGPGIKKTERRARSSPKSNDADLQEYELEVKRVQDILSGIEKPQVSNIQARTVVLSWTPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGVTWVTLQWSKPEGCSPEEVVTYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRPLIKGPVMSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEASQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISFTPDGCVLVSWESPESSGADISEYRLEWGEDEESLELVYHGTDTGFEMRDLLPAAQYCCRLQAVNQAGAGPSSELVLCQTPASAPDPVSTLCVLEEETLTAYPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDTSVTVGNTTTHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSNAKMHAADDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPAIKAPRVTQLEGNACEILWETVPPMKGDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCACRRCLDTSQELSGAFSPSAAFVLQRSEVMLTGDMGSLDDPKMKSMMPTDEQFAALIVVGFATLSILFAFILQYFLMK", "length": 1207 }, "evidence": [ { "id": "A0A8V0Z6T3", "url": "https://omabrowser.org/oma/group/A0A8V0Z6T3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q53EP0-1", "protein_name": "Fibronectin type III domain-containing protein 3B", "gene_name": "FNDC3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGDAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIHNSHTAYYPPVTGPGDMPPQFFPQHHLPHTIYGEQEIIPFYGMSTYITREDQYSKPPHKKLKDRQIDRQNRLNSPPSSIYKSSCTTVYNGYGKGHSGGSGGGGSGSGPGIKKTERRARSSPKSNDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSEILAYTIDLGDTSITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCACRRCLDTSQELSGAFSPSAAFVLQRSEVMLTGDMGSLDDPKMKSMMPTDEQFAAIIVLGFATLSILFAFILQYFLMK", "length": 1204 }, "evidence": [ { "id": "A0A8V0Z6T3", "url": "https://omabrowser.org/oma/group/A0A8V0Z6T3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NWW9-1", "protein_name": "Fibronectin type III domain-containing protein 3B", "gene_name": "Fndc3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQPHLPPTIYSEPEIIPLYGMSSYVTREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKNSCATVYNGYGKGHSGGSSGGGGGGSGGGPGIKKTERRARSSPKSSDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAVYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRPLIKGPVTSHGFSVKWDAPKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKGVHLEWDVPASESGCEVSEYSVEMTEPENVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAPRVSFTPDGCVLVGWESPASPGADISEYRLEWGEDEQSLELVYHGPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSTLCVLEEEPPSAHPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDSCITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECAASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPMRGDPVSYVLQVLVGRDSEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSAAFMLQQREVMLTGDLGGMEEAKMKGMMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207 }, "evidence": [ { "id": "A0A8V0Z6T3", "url": "https://omabrowser.org/oma/group/A0A8V0Z6T3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 381, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 409, "end_pos": 411 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6F0-1", "uniprot_ac": "A0A8V0Z6F0", "uniprot_id": "A0A8V0Z6F0_CHICK", "mass": { "chemical_mass": 35208.0, "monoisotopic_mass": 35208.0 }, "refseq": { "ac": "NP_001264483", "name": "JNK1/MAPK8-associated membrane protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" }, "gene_names": [ { "name": "JKAMP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ] }, { "name": "C14orf100", "type": "synonym", "evidence": [ { "id": "NP_001264483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" } ] }, { "name": "JKAMP", "type": "synonym", "evidence": [ { "id": "NP_001264483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" } ] } ], "protein_names": [ { "name": "JNK1/MAPK8-associated membrane protein", "type": "synonym", "evidence": [ { "id": "NP_001264483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" }, { "id": "A0A8V0Z6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01065376.1, HAEL01014422.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On Apr 11, 2013 this sequence version replaced XP_421427.3. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" } ] }, { "annotation": "Inhibition of JNK1/2 leads to reduced viral progeny release, decreased viral transcription and lower virus protein expression; limiting apoptotic cell death as evidenced by blockage of Bax activation, cytochrome c release, and caspase activation", "evidence": [ { "database": "RefSeq", "id": "NP_001264483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" }, { "database": "PubMed", "id": "21968197", "url": "https://glygen.org/publication/PubMed/21968197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JKAMP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0", "locus": { "chromosome": "5", "start_pos": 54311438, "end_pos": 54315680, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017041", "url": "https://www.ensembl.org/id/ENSGALG00010017041" } ] } } ], "crossref": [ { "id": "A0A8V0Z6F0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6F0", "database": "AlphaFoldDB", "categories": [] }, { "id": "423530", "url": "https://www.ncbi.nlm.nih.gov/gene/423530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423530", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPGIYCG", "url": "https://omabrowser.org/oma/group/CPGIYCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Z0Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6F0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12740:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRSAVDIQPACLGLYCGRVVLAVNGSVEVYGDCGVCPRGQRTDDNKICRECVGSPDRYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALLQHITALFECSIAAIVTLLVSDPAGSLHIRSCKVKKLSDWYTMLYNPSPDYITTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPFLVKKIACGLGKSDRFKSIYAALYFFPVLTVLQAVGGGLLYYAFPYIILVLSLVTLAVYLSASEVESFKDLLVRKKRLVVLLSHWLLHAYGIISIPKLDKLEQDLPLLALVPAPAIFYLMTAKYTEPSRILSEGGNGH", "length": 314, "header": "tr|A0A8V0Z6F0-1|A0A8V0Z6F0_CHICK Isoform 1 of JNK1/MAPK8-associated membrane protein OS=Gallus gallus OX=9031 GN=JKAMP PE=4 SV=1 CANONICAL=A0A8V0Z6F0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0/entry#A0A8V0Z0Y3-1", "sequence": { "sequence": "MIRSAVDIQPACLGLYCGRVVLAVNGSVEVYGDCGVCPRGQRTDDNKICRECVGSPDRYDWLYLGFMAMLPLVLHWFFIEWYSGKKRYTIVFIYYAFCLVLMMLLRPFLVKKIACGLGKSDRFKSIYAALYFFPVLTVLQAVGGGLLYYAFPYIILVLSLVTLAVYLSASEVESFKDLLVRKKRLVVLLSHWLLHAYGIISIPKLDKLEQDLPLLALVPAPAIFYLMTAKYTEPSRILSEGGNGH", "length": 245, "header": "tr|A0A8V0Z0Y3-1|A0A8V0Z6F0_CHICK Computationally mapped isoform of JNK1/MAPK8-associated membrane protein OS=Gallus gallus OX=9031 GN=JKAMP PE=4 SV=1 CANONICAL=A0A8V0Z6F0-1" }, "locus": { "chromosome": "5", "start_pos": 54315655, "end_pos": 54312049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041139.1", "url": "https://www.ensembl.org/id/ENSGALT00010041139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024074.1", "url": "https://www.ensembl.org/id/ENSGALP00010024074.1" } ] } }, { "isoform_ac": "A0A8V0Z6F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0/entry#A0A8V0Z6F0-1", "sequence": { "sequence": "MIRSAVDIQPACLGLYCGRVVLAVNGSVEVYGDCGVCPRGQRTDDNKICRECVGSPDRYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALLQHITALFECSIAAIVTLLVSDPAGSLHIRSCKVKKLSDWYTMLYNPSPDYITTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPFLVKKIACGLGKSDRFKSIYAALYFFPVLTVLQAVGGGLLYYAFPYIILVLSLVTLAVYLSASEVESFKDLLVRKKRLVVLLSHWLLHAYGIISIPKLDKLEQDLPLLALVPAPAIFYLMTAKYTEPSRILSEGGNGH", "length": 314, "header": "tr|A0A8V0Z6F0-1|A0A8V0Z6F0_CHICK Isoform 1 of JNK1/MAPK8-associated membrane protein OS=Gallus gallus OX=9031 GN=JKAMP PE=4 SV=1 CANONICAL=A0A8V0Z6F0-1" }, "locus": { "chromosome": "5", "start_pos": 54315655, "end_pos": 54312049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041137.1", "url": "https://www.ensembl.org/id/ENSGALT00010041137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024072.1", "url": "https://www.ensembl.org/id/ENSGALP00010024072.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Infectious bursal disease virus-induced activation of JNK signaling pathway is required for virus replication and correlates with virus-induced apoptosis.", "journal": "Virology", "date": "2011-11-25", "authors": "Wei Li, Zhu Shanshan, Ruan Guifeng, Hou Lei, Wang Jing, Wang Bingquan, Liu Jue", "evidence": [ { "database": "RefSeq", "id": "NP_001264483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264483" } ], "reference": [ { "type": "PubMed", "id": "21968197", "url": "https://glygen.org/publication/PubMed/21968197" } ] } ], "pathway": [ { "id": "gga:423530", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423530", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHY1-1", "protein_name": "JNK1/MAPK8-associated membrane protein", "gene_name": "anon-WO0118547.412", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRMYDALERCPGAYCGRSPLGNNSWSSCGVCPRGSRVNQSYACSPCRDELSTYSWLYLGFMTMLPLMMHCFFIDMDAKDRKFSRKQLILTASAFVEVAISAILATLLMEPMWELRLYACDVRKLTDWYTLFYNPSPNYEARVYCTQEAVYPLQTIVLVFYFLCLVNMFLIRPLVSKIMDVGGRSKAPIYSALYFLPLLTFIHALGCGLIYYSFPYLSVAISMVANAIHYSLKLDQTLKALVHSSVWELKNVVIIAVHWMLLAYGLTSLNYHYAFMCLVPFPTLFYILTVRFTDPAEFRELESRIXCGDVQMQIFHARGTRRSTVVIYV", "length": 328 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A287AIT1-1", "protein_name": "JNK1/MAPK8 associated membrane protein", "gene_name": "JKAMP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVDIQPACLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALCECSAAALITLLVSDPVGVLHIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 311 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZZT8-1", "protein_name": "JNK1/MAPK8-associated membrane protein", "gene_name": "Jkamp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 311 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ID72-1", "protein_name": "JNK1/MAPK8-associated membrane protein isoform X1", "gene_name": "Jkamp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVDIQPACLGLYCGKTLLFKNGSNEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSERFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRADRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 311 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BI36-1", "protein_name": "JNK1/MAPK8-associated membrane protein", "gene_name": "Jkamp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 311 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P055-4", "protein_name": "JNK1/MAPK8-associated membrane protein", "gene_name": "JKAMP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVDIQPACLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 311 }, "evidence": [ { "id": "A0A8V0Z6F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6F0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0Z771-1", "uniprot_ac": "A0A8V0Z771", "uniprot_id": "A0A8V0Z771_CHICK", "mass": { "chemical_mass": 22460.0, "monoisotopic_mass": 22460.0 }, "refseq": { "ac": "XP_040536436", "name": "pyroglutamyl-peptidase 1-like protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536436" }, "gene_names": [ { "name": "PGPEP1L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ] }, { "name": "PGPEP1L", "type": "synonym", "evidence": [ { "id": "XP_040536436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536436" } ] } ], "protein_names": [ { "name": "Pyroglutamyl-peptidase I like", "type": "synonym", "evidence": [ { "id": "A0A8V0Z771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771/entry#names_and_taxonomy" } ] }, { "name": "pyroglutamyl-peptidase 1-like protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040536436", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536436" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052582.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040536436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536436" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGPEP1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771", "locus": { "chromosome": "10", "start_pos": 16697009, "end_pos": 16682514, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018704", "url": "https://www.ensembl.org/id/ENSGALG00010018704" } ] } } ], "crossref": [ { "id": "A0A8V0Z771", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z771", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00501", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00501", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859846", "url": "https://www.ncbi.nlm.nih.gov/gene/100859846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1B2", "url": "https://www.orthodb.org/?gene=A0A8V0Z1B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z771", "url": "https://www.orthodb.org/?gene=A0A8V0Z771", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Q4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23402:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23402:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040536436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536436", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1B2-1", 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gallus OX=9031 GN=PGPEP1L PE=3 SV=1 CANONICAL=A0A8V0Z771-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771/entry#A0A8V0Z1B2-1", "sequence": { "sequence": "MDSNSNIVVVTGFGPFRQYLVNSSWEAVKELSKRGLGKNIDLRIMQLPVVYQKAKEQIVRIWTTLHPILTVHVGLASSAKAIIILEQCGKNKGYEEMDACGFHPEGGCCMLNGPEKIESTINMKTIWKNISVEGIDMIFSRDAGRYICDYTYYTSLYYGSGRAAFIHVPPLSKTEQQHLHVDTWDFSMGNKSSFL", "length": 195, "header": "tr|A0A8V0Z1B2-1|A0A8V0Z771_CHICK Computationally mapped isoform of Pyroglutamyl-peptidase I like OS=Gallus gallus OX=9031 GN=PGPEP1L PE=3 SV=1 CANONICAL=A0A8V0Z771-1" }, "locus": { "chromosome": "10", "start_pos": 16696719, "end_pos": 16685546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045219.1", "url": "https://www.ensembl.org/id/ENSGALT00010045219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026998.1", "url": "https://www.ensembl.org/id/ENSGALP00010026998.1" } ] } }, { "isoform_ac": "A0A8V0Z771-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771/entry#A0A8V0Z771-1", "sequence": { "sequence": "MDSNSNIVVVTGFGPFRQYLVNSSWEAVKELSKRGLGKNIDLRIMQLPVVYQKAKEQIVRIWTTLHPILTVHVGLASSAKAIIILEQCGKNKGYEEMDACGFHPEGGCCMLNGPEKIESTINMKTIWKNISVEGIDMIFSRDAGRYICDYTYYTSLYYGSGRAAFIHVPPLSKSVTADSLGKALQTIILEMLKQCWEQRE", "length": 200, "header": "tr|A0A8V0Z771-1|A0A8V0Z771_CHICK Isoform 1 of Pyroglutamyl-peptidase I like OS=Gallus gallus OX=9031 GN=PGPEP1L PE=3 SV=1 CANONICAL=A0A8V0Z771-1" }, "locus": { "chromosome": "10", "start_pos": 16695478, "end_pos": 16685546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045223.1", "url": "https://www.ensembl.org/id/ENSGALT00010045223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027000.1", "url": "https://www.ensembl.org/id/ENSGALP00010027000.1" } ] } }, { "isoform_ac": "A0A8V0Z8Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771/entry#A0A8V0Z8Q4-1", "sequence": { "sequence": "MGRTRLACSKNLQLKRMEVQERARGFGPFRQYLVNSSWEAVKELSKRGLGKNIDLRIMQLPVVYQKAKEQIVRIWTTLHPILTVHVGLASSAKAIIILEQCGKNKGYEEMDACGFHPEGGCCMLNGPEKIESTINMKTIWKNISVEGIDMIFSRDAGRYICDYTYYTSLYYGSGRAAFIHVPPLSKSVTADSLGKALQTIILEMLKQCWEQRE", "length": 213, "header": "tr|A0A8V0Z8Q4-1|A0A8V0Z8Q4_CHICK Computationally mapped isoform of Pyroglutamyl-peptidase I like OS=Gallus gallus OX=9031 GN=PGPEP1L PE=3 SV=1 CANONICAL=A0A8V0Z771-1" }, "locus": { "chromosome": "10", "start_pos": 16695478, "end_pos": 16686405, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045213.1", "url": "https://www.ensembl.org/id/ENSGALT00010045213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026996.1", "url": "https://www.ensembl.org/id/ENSGALP00010026996.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyroglutamyl-peptidase activity", "id": "GO:0016920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016920", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z771" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z792-1", "uniprot_ac": "A0A8V0Z792", "uniprot_id": "A0A8V0Z792_CHICK", "mass": { "chemical_mass": 254449.0, "monoisotopic_mass": 254449.0 }, "refseq": { "ac": "XP_418787", "name": "dnaJ homolog subfamily C member 13 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418787" }, "gene_names": [ { "name": "DNAJC13", "type": "recommended", "evidence": [ { "id": "A0A8V0Z792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ] }, { "name": "DNAJC13", "type": "synonym", "evidence": [ { "id": "XP_418787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418787" } ] } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member C13", "type": "synonym", "evidence": [ { "id": "A0A8V0Z792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 13 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_418787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418787.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792", "locus": { "chromosome": "2", "start_pos": 42212905, "end_pos": 42158950, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018715", "url": "https://www.ensembl.org/id/ENSGALG00010018715" } ] } } ], "crossref": [ { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420688", "url": "https://www.ncbi.nlm.nih.gov/gene/420688", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420688", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420688", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQTYSIC", "url": "https://omabrowser.org/oma/group/PQTYSIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1C6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z792", "url": "https://www.orthodb.org/?gene=A0A8V0Z792", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7T2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7U8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZEQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36983:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36983:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z792-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGPGVAGYLTAGTTSSVMPNIPPSVDNEVGDVS", "length": 2240, "header": "tr|A0A8V0Z792-1|A0A8V0Z792_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#A0A8V0Z1C6-1", "sequence": { "sequence": "MNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKEDRNNMNIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGVSSPSLLTGSSPLHLRSGL", "length": 2233, "header": "tr|A0A8V0Z1C6-1|A0A8V0Z792_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "locus": { "chromosome": "2", "start_pos": 42210698, "end_pos": 42165629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045246.1", "url": "https://www.ensembl.org/id/ENSGALT00010045246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027013.1", "url": "https://www.ensembl.org/id/ENSGALP00010027013.1" } ] } }, { "isoform_ac": "A0A8V0Z792-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#A0A8V0Z792-1", "sequence": { "sequence": "MNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGPGVAGYLTAGTTSSVMPNIPPSVDNEVGDVS", "length": 2240, "header": "tr|A0A8V0Z792-1|A0A8V0Z792_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "locus": { "chromosome": "2", "start_pos": 42212160, "end_pos": 42165629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045260.1", "url": "https://www.ensembl.org/id/ENSGALT00010045260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027025.1", "url": "https://www.ensembl.org/id/ENSGALP00010027025.1" } ] } }, { "isoform_ac": "A0A8V0Z7T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#A0A8V0Z7T2-1", "sequence": { "sequence": "MNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKEDRNNMNIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGPGVAGYLTAGTTSSVMPNIPPSVDNEVGDVS", "length": 2245, "header": "tr|A0A8V0Z7T2-1|A0A8V0Z7T2_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "locus": { "chromosome": "2", "start_pos": 42212160, "end_pos": 42165629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045251.1", "url": "https://www.ensembl.org/id/ENSGALT00010045251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027017.1", "url": "https://www.ensembl.org/id/ENSGALP00010027017.1" } ] } }, { "isoform_ac": "A0A8V0Z7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#A0A8V0Z7U8-1", "sequence": { "sequence": "MNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGPGVAGYLTAGTTSSVMPNIPPSVDNEVGDVS", "length": 2215, "header": "tr|A0A8V0Z7U8-1|A0A8V0Z7U8_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "locus": { "chromosome": "2", "start_pos": 42212160, "end_pos": 42165629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045271.1", "url": "https://www.ensembl.org/id/ENSGALT00010045271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027032.1", "url": "https://www.ensembl.org/id/ENSGALP00010027032.1" } ] } }, { "isoform_ac": "A0A8V0ZEQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792/entry#A0A8V0ZEQ5-1", "sequence": { "sequence": "MSTGRAPPPAGSRFWHKMNIIRENRDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFSLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVILEVTPGGIDQIDPATNKVLCSYDYRNIEGFVDLTGYQGGFCILYGGFSRLHLFASEQREEIIKSAIEHAGNFIGISLRIRKESLEFEQYLNLRFGKYSNDESITSLAEFVVQKITPRHSEPVKRVLALTEACLVERDPATYNIVTLKPLGEVFAIVCDCENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTQKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDIAASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRNNDGVTHAAIDMLCALMCPMHDDYDLRQEQLNKASLLFSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVATNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDKEIATKMQDLALSEGALPRHLHTAMFTISTDQRMLTNRQLSRHLVGLWTAENKTAMNLLKRILPPGLLAYLDSTDPVPEKDADRMHVRDNLKIASDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENIIQKPVILRKRRQRIKIEANWDLFYYRFLQDHARSNLIWNFKTREELRDTLESEMRAFNIDRELGSASVISWNHQEFEVKYECLSEEIKIGDYYLRLLLEEDETEESGAIKKSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFSDTKYIVGMLERCTDRLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHTSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYSFQEMQELWDSGKLTSKTRCWAQGMDGWRPLQVIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHITQLLLTFDPILVEKVAILLFHVMQDNPQLPRFYLSGVFFFIMMYTGSNVLPIARFLKYAHTKQAFKSEETKSQDIVQRSILGHVLPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSNEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKHLCDTLRFPDWPIKDPIKLLKDTLEAWKKEVEKKPPTMSIDDAYEVLNLPKGQGQHEESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKVIDGPDPENIILILKTQSILFNRHKEELKPYKYAGYPMLIKTITIETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGMEVLQEAFNRCVAVLTHSSKPDDMSVQVCGYISKCYSVAAQFEECREKITEMPNIIKDLCRLLYYGKNIPRVASLGVECVSSFALDYWLQTHLFQAGVLWYLLGYLFNYDYTLEESGIQKSEDSNHQEVANSLAKLSLLALSRLGGYLSEEQATPENPAIRKSLAGMLTPYIARKLAVVSATETLKMLNSNTENPYLIWNNGTRAELLEFLESQQESMIKRGECDKSYGSDFVFSDHAKELIVGEIFVRVYNEVPTFQLELPKAFAASLLDYIGSQAQYLHTLMAITQTGKVESNQHGDRLRRVEMALEALRNVIKHNPGSECECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQECVNNIAEAMVLANLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLVGPKVRIMLMKFLPGVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSREKVSTTVREMMLEHFKLQRDNPDANWKLPEDFAVVYGEADGELSVGGVFLRIFIAQPAWVLRKPREFLIALLEKFTELLEKNNPHGETLETITTATVCLFSAQPQLADQVPPLGHLHKILQAMNHKNNAIPKSAIRVVHILSDNELCVRAMASLETISPLMNGMKKRPDVIGVACEALNRMFQKEQNDLVAQALKADLVPYLLKLLEGIGLENLESPSATKAQIVKALKSMSRSLQYGEQVNDILSRSSVWSAFKDQKHDLFISETQTAGYLTGPGVAGYLTAGTTSSVMPNIPPSVDNEVGDVS", "length": 2257, "header": "tr|A0A8V0ZEQ5-1|A0A8V0ZEQ5_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member C13 OS=Gallus gallus OX=9031 GN=DNAJC13 PE=1 SV=1 CANONICAL=A0A8V0Z792-1" }, "locus": { "chromosome": "2", "start_pos": 42212160, "end_pos": 42158963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045279.1", "url": "https://www.ensembl.org/id/ENSGALT00010045279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027034.1", "url": "https://www.ensembl.org/id/ENSGALP00010027034.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420688", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420688", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AFJ7-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C13", "gene_name": "Dnajc13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIIRENKDLACFYTTKHSWRGKYKRVFSVGTHAVTTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFNLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFAEGKITGRRYNCYKHHWSDTRRPVILEVTPGGFDQINPVTNRVLCSYDYRNIEGFVDLSDYQGGFCILYGGFSRLHLFASEQREEIIKSAVEHAGTYIGVSLRTRKEPLEFEQYLSLRFGKYSTDESITSLAEFVVQKISPRHSEPVKRVLAVTETCLVERDPATYNIATLKPLGEVFALVCDSENPQVFTIEFIKGQVRKYSSTERDSLLASLLDGVRASGNRDVCVKMTPTHKGQRWGLLSMPIDEEVESLHLRFLAAPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLAQEGDVVASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGMKVVKALKRSNNGVIHAAVDMLCALMCPMHDDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTLFKLFQHPSMAIVKGAGLVMKAIIEEGDREIATKMQDLALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNTTATNLLRRILPPGLLAYLDSSDPVPEKDADRMHVRDNVKIAMDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENINQKPVVLRKRRQRIKIEANWDLFYYSFLIACVFRFSQDHARSNLIWNFKTREELKDTLESEMRTFNIDRELGSASVISWNHHEFEVKYECLAEEIKIGDYYLRLLLEEDENEESGSIKRSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEDIGPFTDTRYIIGMLERCTDKLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHVSRATVPLQSNVIEASPDMKRESEKEWYFGNADKERSGPYGFHEMQELWAKGMLNAKTRCWAQGMDGWRPLQAIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDSTCLPHLIQLLLTFDPILVEKVAILLHHIMQDNPQLPRLYLSGVFFFIMMYTGSNVLPVARFLKYTHTKQAFKSEESKGQDIFQRSILGHILPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSSEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKQLCDTLRFPDWPIKDPVKLLKDSLDAWKKEVEKKPPMMSIDDAYEVLNLPVGQGLHDESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSTKIVDGPDPENIILILKTQSILFNRHKEELQPYKYAGYPMLIRTITMETSDDLLFSKESPLLPAAAELAFHTVNCSALNAEELRRENGLEVLQEAFSRCVAVLSRSSKPSDMSVQVCGHISRCYSVAAQFEECREKITEMPGIIKDLCRVLYFGKCIPRVAALAVDCVSSFAVDFWLQTHLFQAGILWYLLVYLFNYDYTLEESGIQKNEETNQQEVANSLAKLSVHALSRLGGYLPEDQATPENPTVRKSLAGMLTPYIARKLAVVSATEILKMLNSNTENPYLMWNNSTRAELLEFLESQQENMIKKGDCDKTYGAEFVYSEHAKELIVGEIFVRVYNEVPTFQLEVPKEFAASLLDYIGSQAQYLHTFMAITHAAKVESEQHGDRLPRVEMALEALRNVIKYNPGSESECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQDCVNNIAESLVLSNLLALLHSLPSSRQLVLETLYALASNTKIIKEAMAKGALIYLLDMFCNSTHPQVRSQTAELFAKMTADKLIGPKVRITLMKFLPSVFMDAMRDNPEAAVHIFEGTHENPELIWNDSSRDKVSTTVREMMLEHFKNQRDNPDMNWKLPEDFAVVFGEAEGELAVGGVFLRIFIAQPAWVLRKPREFLIALLEKLTELLEKNNPHGETLETLTMATVCLFSAQPQLADQVPPLGHLPKVIQAMNHRNNAIPKSAIRVIHVLSDNELCVRAMASLETIGPLMNGMRKRADTVGLACEAINRMFQKEQSELVAQALKAELVPYLLKLLEGIGLESLDSPAATKAQIVKALKAMTRSLQYGEQVNEILSRSSVWSAFKDQKHDLFISDSQTAGYLTGPGVAGYLTAGASSSAMSNLPPPVDHEAGDLGYQT", "length": 2251 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z7S0-1", "protein_name": "Receptor mediated endocytosis 8, isoform A", "gene_name": "Rme-8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLPPKENVDLECFLVTKHSWKGRYKRILSIGTAGISTYNPDKLDLTNRWSYSDIVAAAPSKTTNIPHDFVITIKKDKKLDTIKLSSEYRNDILSSILKYYKEFADKPKNAQRFSAYKYHWSGISLPTVLEVTPCSLDQLDPTTNDVLASYMYKDIEGIIAGISDYEGGIVMAYGGFSRLHLFKALNHHEIVQNIAQRSAQFLGIETKILKSQITLEQFERQRFGKFSGDQFQTSSTEFSVHKITPRHPDPVKRILCLTEVTLLERDPQTYSVCTLRPLTDVFALVRDKDNLQRFSIEYKNGIVRNYSTNDRDSLLATVLDAVRSSGNQDVHVRIGNTPRGKRYVPLNSSVDEETEANLMRLVINNFQNPSKRYEILERFNANVPHSGLNYSVTQDSLFAENKDKLILSALQALAQKELDSPTAQLSNLELEAIFHALTRLLASKVGYAAFTNLPGFREIIGTKVVAALRRKDLAVTYSAIDMINSLMHSVNSDHDLKQEQLNKSSILSSKSFLETLLNMWTTHVSHGSGALVLSAMLDFMTFALCVPYSETTDGKQFDTLLELVADRGRYLYKLFQHPSLAIVKGAGLVLRAIIEEGELQVAQQMQALALDEAALCRHLLVALYTPSNDPTQTTQRQLSRHLIGLWLTDSEEAMELFKRIFPAGLLTFLESEETVPESDVEEDKLNFRDNLKFAIQHSNKTRKNVIEKHLQGIKHWGMNLIEKQDGAAQALKNRPVVLRNRRQKKKTSDVVVNLPFFFYSFAKDHSLPNLIWNHKTREELRMCLENELRQFLNDRDLAGQMIVAWNYQEFEVAYQCLADEIKIGDYYIRLILEKDDWPQNLVKDPIELFNALYRRVLCRQRVNDDQMTVFSLQALAKVYRRYHAEIGKFNDMSYILQLSDRCLSPSMRDALINLISCLVLEKSNSRALIDHVQCLVDLITLAHLHKGRAQLNTKTNVIEAGPNMGTYEEKDWYYNIEKDGQKPERQGPITYSELKELWQKGLITPKTRCWAIGMDGWRSLQQIPQLKWCLIAKGTPLYDETELSSKILDILIKCTSFFPSRTQNGVAVLIPGPKLSRKLSEFICLPHVVQVCLTHDPGLLERVATLLYQIMEDNPEMPKVYLTGVFYFMLMYTGSNILPITRFLKMTHMKQGFRSEETSQSGIMHRSILGQLLPEAMVCFLENYSAEKFAEIFLGEFDTPEVIWSSEMRRLLIEKIAAHIADFTPRLRGHTMARYPYLAIPVISYPQLENELFCHIYYLRHLCDTQKFPNWPISDPVQLLKHTLDAWRKEVEKKPPQMTIQQAYQDLGIDLTKTPKPDESMIRKSYYKLAQMYHPDKNPNGREIFEKVNQAYEFLCSRNVWSSGGPDPNNIVLILRTQSILFERYPDVLRPYKYAGYPQLIKTIRLETRDDELFSKEAQLLTAASELCYHTVHCSALNAEELRREEGIEALLEAYTRCVSILGVDSKPDSLHYQVISNVTRCFEVACNFEKCKQKIIQLPQLLSDVCRVVYFKHTLSVSLVTSLAANNYDLQCQLSRNGVLWSLLLFIFEYDYTLDESGVDVSDKSNQQQLANNLAKMAVLGCIALAGYSMELRQKPVTGSETNSPAAKAPPVIKPKPSVSAASSSTYTQNAHNPLQSKQLAITSGKEKESDTSSGSSDTASSTPTESEQQQQLTKTRTSAIQQKYIVTGEAKNSLIKQVLDRLLTRYISNQLATVRDSDVLKLLTANTRNPYLIWDNGTRAQLKDFLEQQRTASAKETHEDIAQVSELVSSFEFDAHKDELQIGGIFIRIYNDMPTHPIAQPKLFIMDLLEYLKHAYQFLQYKKNPASTAAPVNATPKMGNDGILTPTLAPNHPQLQQASTGKSGTTFDEVLTAYNRSKSRKKLETDALTEQQLALQQSKYDFSSDGKIELHITMVLKALIAVIKANAEVEIQCIGNFDMIFGFLASNIFPDNSTVKAVALEVVSLVSRNKECVSEVAACEILGNYLVALKDPELRASQVKVLETLSGLMNVQEMIKEAQAKGATIYLLDMFCNSRNPQIREMCAGILAKMTADRLSGPKVRITVSKFLPALFIDAMVESPATSVQLFESIHEHPELIWNDTTRSNVCDAVADTCQRFYQLQKANSRHVWKDPEILKDIVSNEIVVAGVYLRLFVSNPAWTLRKPKQFLSDLLDFVVEQIGKSSSEQDVLDLSTTALVELLRSQPNLADDIPVLGHIPKLFNLLSVQPKNTLSVLHQLSLSEFCVSAISQTECVAPLKKCMEHNRDCIEKACEALSRLFKHQHDSLISQSLEVGLIPFLLGLLDSRLEFVDNPSAVKAQIVAALKGMTHNLNYGDRVTQILLKHPVWAEFKDQRHDLFIADTTIRGYLTGVNPTAGYLTAGPAQSVEVLTSPPPIDRDDPSARPPID", "length": 2408 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1MDR7-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C13", "gene_name": "DNAJC13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNIIKENKDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFNLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDTRKPVVLEVTPGGFDQINPATNRVLCSYDYRNIEGFVDLSDYQGGFCILYGGFSRLHLFASEQREEIIKSAIDHAGNYIGISLRIRKEPLEFEQYLNLRFGKYSTDESITSLAEFIVQKISPRHSEPVKRILALTETCLVERDPATYNIATLKPLGEVFALVCDSENPQLFTIEFIKGQIRKYSSTERDSLLASLLDGVRASGNRDVCVKMTSTHKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDVVASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGVKVVKALKRSNNGVIHAAVDMLCALMCPMHDDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTLFKLFQHPSMAIIKGAGLVMKAIIEEGDKEIATKMQELALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNATATNLLKRILPPGLLAYLDSSDPVPEKDTDRMHVRDNVKIAMDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENINQKPVVLRKRRQRIKIEANWDLFYYRFGQDHARSNLIWNFKTREELRDSLESEMRAFNIDRELGSANVISWNHHEFEVKYECLAEEIKIGDYYLRLLLEEDENEDSGSIKRSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFTDTRYIIGMLERCTDKLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHVSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYGFHEMQELWTKGMLNAKTRCWAQGMDGWRPLQAIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPRVKRLLSDNACLPHIIQLLLTFDPILVEKVAILLYHIMQDNPQLPRLYLSGVFFFIMMYTGSNVLPVARFLKYTHTKQAFKSEETKGQDIFQRSILGHILPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSSEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPVINYPQLENELFCNIYYLKQLCDTLRFPDWPIKDPVKLLKDTLDAWKKEVEKKPPTMSIDDAYELLNLPQGQGPHDESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKIMDGPDPENIILILKTQSILFNRHKEDLQPYKYAGYPMLIRTITMETSDDLLFSKESPLLPAAAELAFHTVNCSALNAEELRRENGIEVLQEAFSRCVAVLNRSSKPSDMSVQVCGHISRCYSVAAQFEECREKITEMPGIIRDLCRVLYFGKGIPRVAALGVECVSSFAVDFWLQTHLLQAGILWHLLGYLFNYDYTLEESGIQKSEETNQQEVANSLAKLSVRALSRLGGYLPEEQTTPENPTIRKSLAGMLTPYVARKLAVISATEILKMLNSNTESPYLIWNNSTRAELLEFLESQQESMIKKGDCDKTYGSEFVYSDHAKELIVGEIFVRVYNEVPTFPLEVPKAFAASLLDYIGSQAQYLHTFMAITHAAKVESEQHGDRLPRVEMALEALRNVIKYNPGSESECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQDCVNNIAESMVLSNLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMARGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLIGPKVRITLMKFLPSVFMDAMRDNPEAAVHIFEGTHENPELIWNDSSRDKVSTTVREMMLEHFKNQQDNPDVNWKLPEDFAVVFGEAEGELAVGGVFLRIFIAQPAWVLRKPREFLTALLEKLTELLEKNSPHGETLETLTMATVCLFSAQPQLADQVPPLGHLPKIIQAMNHRNNAIPKSAIRVIHALSENELCVRTMASLETIGPLINGMKKRPDTIGLACEAINRMFQKEQSELVAQALKVDLVPYLLKLLEGIGLENLDSPAATKAQIVKALKAMTRSLQHGEQVNEILSRSSVWSAFKDQKHDLFISESQTAGYLTGPGVAGYLTAGTSSSVMSNLPPPVDHEAGDLGYQT", "length": 2243 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IVL6-1", "protein_name": "DnaJ homolog subfamily C GRV2", "gene_name": "GRV2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSVSRGAVASTTGGAVEEPEYLARYLVVKHSWRGRYKRILCISSGGIVTLDPNTLAVTNSYDTGSNFDGASPLVGRDENTESVGGEFTVNVRTDGKGKFKAMKFSSRCRASILTELYRLRWNQIRPVAEFQVLHLRRRNAEWVPYKLKITFVGLELVDSKSGNSRWILDFRDMGSPAIILLSDAYRTKSADSAGFVLCPMYGRKSKAFRAAPGTTNSSIVASLAKTAKSMVGVFLSVDDSQLLTVSEYMTRRAKEAVGAEETPNGWWSVTRLRSAAHGTLNMPGLSLAIGPKGGLGEHGDAVALQLILTKASLVERRIDNYEVVIVRPLSSVSSLVRFAEEPQMFAIEFSDGCPVLVYASISRDNLLAAILDTLQTEGHCPIPVLPRLTMPGHRIDPPCGRVSLISGPQHLVADLETCSLHLKHLAAAAKDAVAEGGSVPGCRARLWRRIREFNACIPYTGVPANSEVPEVTLMALITMLPSTPNLPVDAPPLPPPSPKAAATVIGFVTCLRRLLSSRSAASHIMSFPAAVNRIMGLLRNGSEGVAAEAAGLIASLIGGWSADLSTAPDSRGEKHATIMHTKSVLFAQQGYVTILVNRLKPMSVSPLFSMAIVEVFEAMVCDPHGETTQYTVFVELLRQIAALRRRLFALFAHPAESVRETIAVIMRTIAEEDAIAAESMRDAALRDGALLRHLLNAFSLPASERREVSRQLVALWADSYQPALDLLSRVLPPGLVAYLHTRPDDVVDDTDQEGSSTNRRQKRLLQQRRGRIAKGMGAQDIPLPPGNNVEAGDAAKHMSANASVPDNFQRRAADSSSEASNPQASAFPGVDSTIAGVSQNGYPAFASVTTNANGHEQPETNASDVVGSDPNLYGIQNSVLPAPAQVIVESTAVGSGKLLLNWREFWRAFGLDHNRADLIWNERTRQELIEALKAEVHNLDVEKERTEDISPGDVEATTGQEIIPRISWNYSEFSVSYRSLSKEVCVGQYYLRLLLESGNAGKAQDFPLRDPVAFFRALYHRFQCDADMGLTIDGAVPDELGSSGDWCDMSRLDGFGGGGGASVRELCARAMAIVYEQHYNTIGPFEGTAHITALIDRTNDRALRHRLLLLLKALVKVLLNVEGCVVVGGCVLAVDLLTVVHENSERTPIPLQSNLIAATAFMEPPKEWMYIDKGGAEVGPVEKDVIRSLWSKKDIDWTTKCRALGMSDWKKLRDIRELRWAVAVRVPVLTPSQVGDAALSILHSMVSAHSDLDDAGEIVTPTPRVKRILSSTRCLPHIAQALLSGEPVIVEAGAALLKDVVTRNSKAMIRLYSTGAFYFALAYPGSNLYSIAQLFSVTHVHQAFHGGEEATVSSSLPLAKRSVLGGLLPESLLYVLERSGPAAFAAGMVSDSDTPEIIWTHKMRAENLICQVLQHLGDYPQKLSQHCHSLYDYAPMPPVTYPELRDEMWCHRYYLRNLCDEIQFPNWPIVEHVEFLQSLLVMWREELTRKPMDLSEGEACKILEISLNNVSSDDLNRTASVELNEEISNISKQIQNLDEEKLKRQYRKLAMRYHPDKNPEGREKFLAVQKAYECLQATMQGLQGPQPWRLLLLLKAQCILYRRYGHVLRPFKYAGYPMLLDAVTVDKDDNNFLSNDRSPLLVAASELVSLTCAASSLNGEELVRDGGVQLLSTLLSRCMCVVQPTTSQHEPAAIIVTNVMRTLSVISQFESARAGFLELPSLIEDIVHCTELERVPAAVDAALQSIAKVSVFPELQHGLLKAGALWYILPLLLQYDSTAEESNSVESHGVGVSIQIAKNEHALQASQALSRLTGLCADESLTPYNATAADVLKALLTPKLASLLKDEVAKDLLSKLNTNLETPEIIWNSATRSELLNFVDEQRACQCPDGSYDLKNAQSFSYDALSKEVFVGNVYLKVYNDQPDSEISEPESFCNALIDFISSLVHTELPSVSEDQNLIEDRNSSNDTPELQSSVAEPSLIEEHSDHQPSSEGMKNEECFLIDHLQLGLTALQNLLTKYPDLASVFSSKERLLPLFECFSVAIASKTDIPKLCLNVLSRLTAYAPCLETMVSDGSSLLLLLQMLHSAPSFREGALHVLYALASTPELAWAAAKHGGVVYILELLLPLQKEIPLQQRAAAASLLGKLVAQPMHGPRVAITLVRFLPDGLVSIIRDGPGEAVVHALERTTETPELVWTPAMAASLSAQIATMASDIYREQQKGSVIEWDVPEQSAGQQEMRDEPQVGGIYVRRFLKDPKFPLRNPKRFLEGLLDQYLSAMAATHYEQHPVDPELPLLLSAALVSLLRVHPALADHIGHLGYVPKLVAAVAYEGRRETMSSGEVKAEEIGSDGVNESTDPSSLPGQTPQERVRLSCLRVLHQLAASTTCAEAMAATSAGNAQVVPLLMKAIGWLGGSILALETLKRVVVAGNRARDALVAQGLKVGLIEVLLGLLDWRTGGRYGLSSHMKWNESEASIGRVLAVEVLHGFATEGAHCSKVREILDASEVWSAYKDQKHDLFLPSNTQSAAGVAGFIENSSNSLTYALTAPPPPSHP", "length": 2554 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O75165-1", "protein_name": "DnaJ homolog subfamily C member 13", "gene_name": "DNAJC13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIIRENKDLACFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQGTEFNLTFRKGSGKKSETLKFSTEHRTELLTEALRFRTDFSEGKITGRRYNCYKHHWSDSRKPVILEVTPGGFDQINPATNRVLCSYDYRNIEGFVDLSDYQGGFCILYGGFSRLHLFASEQREEIIKSAIDHAGNYIGISLRIRKEPLEFEQYLNLRFGKYSTDESITSLAEFVVQKISPRHSEPVKRVLALTETCLVERDPATYNIATLKPLGEVFALVCDSENPQLFTIEFIKGQVRKYSSTERDSLLASLLDGVRASGNRDVCVKMTPTHKGQRWGLLSMPVDEEVESLHLRFLATPPNGNFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNAITALLSQEGDVVASNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGVKVVKALKRSNNGIIHAAVDMLCALMCPMHDDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTLFKLFQHPSMAIIKGAGLVMKAIIEEGDKEIATKMQELALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNATATNLLKRILPPGLLAYLESSDLVPEKDADRMHVRDNVKIAMDQYGKFNKVPEWQRLAGKAAKEVEKFAKEKVDLVLMHWRDRMGIAQKENINQKPVVLRKRRQRIKIEANWDLFYYRFGQDHARSNLIWNFKTREELKDTLESEMRAFNIDRELGSANVISWNHHEFEVKYECLAEEIKIGDYYLRLLLEEDENEESGSIKRSYEFFNELYHRFLLTPKVNMKCLCLQALAIVYGRCHEEIGPFTDTRYIIGMLERCTDKLERDRLILFLNKLILNKKNVKDLMDSNGIRILVDLLTLAHLHVSRATVPLQSNVIEAAPDMKRESEKEWYFGNADKERSGPYGFHEMQELWTKGMLNAKTRCWAQGMDGWRPLQSIPQLKWCLLASGQAVLNETDLATLILNMLITMCGYFPSRDQDNAIIRPLPKVKRLLSDSTCLPHIIQLLLTFDPILVEKVAILLYHIMQDNPQLPRLYLSGVFFFIMMYTGSNVLPVARFLKYTHTKQAFKSEETKGQDIFQRSILGHILPEAMVCYLENYEPEKFSEIFLGEFDTPEAIWSSEMRRLMIEKIAAHLADFTPRLQSNTRALYQYCPIPIINYPQLENELFCNIYYLKQLCDTLRFPDWPIKDPVKLLKDTLDAWKKEVEKKPPMMSIDDAYEVLNLPQGQGPHDESKIRKAYFRLAQKYHPDKNPEGRDMFEKVNKAYEFLCTKSAKIVDGPDPENIILILKTQSILFNRHKEDLQPYKYAGYPMLIRTITMETSDDLLFSKESPLLPAATELAFHTVNCSALNAEELRRENGLEVLQEAFSRCVAVLTRASKPSDMSVQVCGYISKCYSVAAQFEECREKITEMPSIIKDLCRVLYFGKSIPRVAALGVECVSSFAVDFWLQTHLFQAGILWYLLGFLFNYDYTLEESGIQKSEETNQQEVANSLAKLSVHALSRLGGYLAEEQATPENPTIRKSLAGMLTPYVARKLAVASVTEILKMLNSNTESPYLIWNNSTRAELLEFLESQQENMIKKGDCDKTYGSEFVYSDHAKELIVGEIFVRVYNEVPTFQLEVPKAFAASLLDYIGSQAQYLHTFMAITHAAKVESEQHGDRLPRVEMALEALRNVIKYNPGSESECIGHFKLIFSLLRVHGAGQVQQLALEVVNIVTSNQDCVNNIAESMVLSSLLALLHSLPSSRQLVLETLYALTSSTKIIKEAMAKGALIYLLDMFCNSTHPQVRAQTAELFAKMTADKLIGPKVRITLMKFLPSVFMDAMRDNPEAAVHIFEGTHENPELIWNDNSRDKVSTTVREMMLEHFKNQQDNPEANWKLPEDFAVVFGEAEGELAVGGVFLRIFIAQPAWVLRKPREFLIALLEKLTELLEKNNPHGETLETLTMATVCLFSAQPQLADQVPPLGHLPKVIQAMNHRNNAIPKSAIRVIHALSENELCVRAMASLETIGPLMNGMKKRADTVGLACEAINRMFQKEQSELVAQALKADLVPYLLKLLEGIGLENLDSPAATKAQIVKALKAMTRSLQYGEQVNEILCRSSVWSAFKDQKHDLFISESQTAGYLTGPGVAGYLTAGTSTSVMSNLPPPVDHEAGDLGYQT", "length": 2243 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54LZ3-1", "protein_name": "J domain-containing protein", "gene_name": "dnajc13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAPNTTSVDEFINAHHRSLSLWYTIKHSWKKKKRFLSIDPINLTTHDVSTWENTNQWAWENGIADVQPSEKHPEQVVIITKKDGKKKDTLNFESDHRSDLLTDLQRSLSVVRAAEKQGKSIDQINYRHLGRTGYVYEMSLRELMTGLYKSYSAKKLKRNGTWLDVKLTVCSCSIEETDADSQVNGQQTKIRASYFFKDFTKIESLADNSSAFLFYFSGEQNQGVASDLFIVNDPKFIENIVAYSKKFVGHEIKFSKSSTSLQEYPTAHRHKRHGKDDDETLVSIIDFTVTKISNRHSTPISRLLTLSTSKIVERDLTSYAIVTTRPYSTIACFVRYDSDSQRLSIQYKDGLLRTYTSSSRDALIASALDFCRSAGNTNATVFTSQIVRGMKITPHHVIPNEDVQESYIRLFENKTFDFENLSVSQITLSLDGFISNIPYSGLSNTFSEKNGKVVLNAIQKILSGLKISGLGSSSSSSSSALSTPGSPQLPTQDDKNDLELISVVLQMLRRVVATRVGFELFTHFPHCKVPLINLLRKSIQCIDDTIAYYALDLLIALIQPAFEGDYEPGQCQANKRELFLSIDLNKTIFEIIQKHSSAGTGSLVLSSAIELLTLLLCDPYSETTDSTIFNDLLTRVGKLGKDLFKLFVHQCPAISKNAGMLMSVVINEGEEELAKQMQIISVVEGALLRHLHDSLFLKINSNQNNPTNLRNQSKREMSKQLISLWTAENKVCRQLLDRIFPRGLVQFLDSQEEAPKEQLLESKQGTTGPKHIKLGVFANWRMKKIIKTRELMAKATTRVRKETKPMRPYNWAMFFHQFNQDHRDANLIWNHTTREELRESMDNEIRLFQQELEAAGREPIAWNDEDFEVPYPSLKKEISVGGYYISLLVDGTSKGIKLINPGLFFNELWQNFLLNESADQKALCLRAMTLVFTHYHTHPSMTHPFSNLSHLIELLENTFDVILRDRLLLFIRSLLQVKSNAKIFIDNRGIYRLLDLITLIHTHYTYGEEGKLLPEWYYAVDVQQEGSGVIQQQKAGPVSRTDLFDLLNSKKINRNTKCWAQGTEKWKPLYQIPELRWTIMNGLTHGNVGGVLPKAELGSVILDILNALCSFRPTRHPVTHAVIRPLPRVKRIICEPLNLPRIVQVLLSGQDILVEKTATLLASLLVDNSIVTSKFYLTGAFFFMMLYPNSNVLPIVQLLQIIHNKQHLITSDESLSRRSILLPLLPEALICYLENYTPENFSSKFLSDNDDPETIWNSSMRKVMREKIELHLASLPQRLHSNTTTIYEYVPIPKIVFEELEGELFCHSFYLSRLCNTRKFPNWPIKQPLELFKSVLLVWSEEAVKAPQSMSVDEALEVLNLKPNKGANGKAHNYKDDDIRKAYYKLAVKYHPDRNPDGREMFEKIQEAYELLSTVNNIDNERGSDKKISLLLLTQVILYTRFMDLFRPFKYPAYPQLWKLINELLVNDKAFDNTNKTPLISPAMALLYLTVEASPLNSEEITRNNGVPIIAKCFDKAVTITFQPIDIPTLIIQTTPISPSFAGKQHKGDLPEPNKDGSTSTSSTNPPDFNSTTEQQSAPKATATPSPTTGNALITIRSSKFNINDHQDGGADIPGEVIGSALRTFAVMAKFPGSRKQLEANNLSLKICENICKCLYLSYSHPHIVTYALEAVYQFAREDDELQQSIINAGVTWHLLRLLYGYDHTLFNSGITVNTDSNRIMIANIHAKLSLKSIRRFSGIKSEEDMEGYVEPSDKPTEPVKKPAAPVVQVPKGPIAVPIPELNGQLQITGGSPTTQPQQSQSAPTTSTSTPTIDPLGGSGGVTNSTTSNSSPTQQSQPSQQQQQQPQQSSSSSSSSSPPQQPGNQLSTQQKINTSQINSSPTQNSQSSTTAQAQKEAAAQAQKEAAAQQKYQKELKEYMEKPETEFNKMVRDMVTVFLTPHIVLRLKMPIGTIPSKHYHKLLTEMNTKHETAAFIWNNSTREDLMEYLNKRLDDAYCNPTTIHPFSTDTFTYKSLSNELKVGGYYLRVYNANPSAPTNATTPIQELFAHLVEFLAKERTTNECPVRNPDKKLWDLYIWKITQALESLRNVVQFGKVNPNLYNMAGSNRMRLLFSFLAHQDNQKIQKLALESLLLVTSNIECINHISQLATEPEGSLLPYLLQLLARPNPATLELALKVEHSLVAISQHVIDTINHCGLVYLLDVFSNNQITMENRIKAVGVLGRMIIDKVHGPRVILLIGKFIPPVFNSTMTEDPQQTVMVFDAQHENPELIWNNNTRAHLKETLTKMQKEYQAQLVQARTYNLHWKLPSEDYQVSYSLGGEDELVIGGVYISLFLKQPGWSLRNPRKFLLDVFDLLLKLASTSEVNSTLDPKIQPLSLAIISLFQHHNVLSDQLPSTGYIEKILPLLGHSVSQIRSLMINILHSMSESQVCVDHLAKVGNVWSHLARAVSLPNDNLPLTAECIGKILALNRCEKTCLSEQAARSDFINQSLKLLERGKGVSPTTQALIVNYLKKLEMDPLHGQIITEILDKSEIWASYSSQSHDLFITGPAANTAGLLTGGTSATSVGLLTSTSFNSTSLGKNDEPPPLL", "length": 2592 }, "evidence": [ { "id": "A0A8V0Z792", "url": "https://omabrowser.org/oma/group/A0A8V0Z792/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of early endosome to late endosome transport", "id": "GO:2000641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000641", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" }, { "name": "regulation of early endosome to recycling endosome transport", "id": "GO:1902954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z792", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1431, "end_pos": 1433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1646, "end_pos": 1648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1865, "end_pos": 1867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z792" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 1301, "end_pos": 1358, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1039, "end_pos": 1041 }, { "start_pos": 1431, "end_pos": 1433 }, { "start_pos": 1646, "end_pos": 1648 }, { "start_pos": 1865, "end_pos": 1867 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 645, "end_pos": 647 } ] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z782-1", "uniprot_ac": "A0A8V0Z782", "uniprot_id": "A0A8V0Z782_CHICK", "mass": { "chemical_mass": 87837.0, "monoisotopic_mass": 87837.0 }, "refseq": {}, "gene_names": [ { "name": "LRCH2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782" } ] } ], "protein_names": [ { "name": "Leucine rich repeats and calponin homology domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z782", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782", "locus": { "chromosome": "4", "start_pos": 2818383, "end_pos": 2854749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018721", "url": "https://www.ensembl.org/id/ENSGALG00010018721" } ] } } ], "crossref": [ { "id": "A0A8V0Z782", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z782", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21271", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21271", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1D1", "url": "https://www.orthodb.org/?gene=A0A8V0Z1D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z782", "url": "https://www.orthodb.org/?gene=A0A8V0Z782", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8R9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z1D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z782", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z782-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSGGGGGGGRPRCCYCGAGLRRAKMAAGQGGGGGGNGGGSSNSSGGSSSNNNGTGGLGIPAHLTLSFSAGPHWGAATLPQPHTVRSLDRALEEAGSSGILCLSGRKLRDFPGSGYDLSDTTQADLSKNRFTEIPPDVWLFAPLETLNLYHNCIKSIPESIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLRDLMELDISCNELQVLPQQIGKLQSLRELNIRRNNLHMLPDELGDLPLVKLDFSCNKITEIPICYRKLRHLQVIVLDNNPMQIPPAQICLKGKVHIFKFLSIQACLRIDKKPDSLDLPSLGKRIPSQPLTDSIEDFYPNKNHGPDSGIGSDNGDKRLSTTEPSDDDTISLHSQVSESTREQTLRNDNHVMGNKLDPQKDQEVYDYIDPNAEEGAVPEQGDVQIGPLLSYIKERGKHPEKSQKIEHHEDWGDEKRLQKEQLLAEEDDEIKEVTDLRKIAAQLLQQEQKHRRRPLSYRTSFSEKLFQRTRAAGRASRLLNHSASVSTRNRPKQPVESEKCISTDEVNSPVSPYSWQPLENQKDSVDDQRWPETQPIIWQNEERRRSKQIRKEYFKYKSSRKSSSGNENDEDYERTDSNTHGPFGLKPRSAFSRAARQDYGAMDPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVPQERLCLPHHILEERGLVKVGLTVQALLELPTLKVSQLSAM", "length": 785, "header": "tr|A0A8V0Z782-1|A0A8V0Z782_CHICK Isoform 1 of Leucine rich repeats and calponin homology domain containing 2 OS=Gallus gallus OX=9031 GN=LRCH2 PE=4 SV=1 CANONICAL=A0A8V0Z782-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782/entry#A0A8V0Z1D1-1", "sequence": { "sequence": "MRSGGGGGGGRPRCCYCGAGLRRAKMAAGQGGGGGGNGGGSSNSSGGSSSNNNGTGGLGIPAHLTLSFSAGPHWGAATLPQPHTVRSLDRALEEAGSSGILCLSGRKLRDFPGSGYDLSDTTQADLSKNRFTEIPPDVWLFAPLETLNLYHNCIKSIPESIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLRDLMELDISCNELQVLPQQIGKLQSLRELNIRRNNLHMLPDELGDLPLVKLDFSCNKITEIPICYRKLRHLQVIVLDNNPMQIPPAQICLKGKVHIFKFLSIQACLRIDKKPDSLDLPSLGKRIPSQPLTDSIEDFYPNKNHGPDSGIGSDNGDKRLSTTEPSDDDTISLHSQVSESTREQTLRNDNHVMGNKLDPQKDQEVYDYIDPNAEEGAVPEQGDVQIGPLLSYIKERGKHPEKSQKIEHHEDWGDEKRLQKEQLLAEEDDEIKEVTDLRKIAAQLLQQEQKHRLLNHSASVSTRNRPKQPVESEKCISTDEVNSPVSPYSWQPLENQKDSVDDQRWPETQPIIWQNEERRRSKQIRKEYFKYKSSRKSSSGNENDEDYERTDSNTHGPFGLKPRSAFSRAARQDYGAMDPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVPQERLCLPHHILEERGLVKVGLTVQALLELPTLKVSQLSAM", "length": 759, "header": "tr|A0A8V0Z1D1-1|A0A8V0Z782_CHICK Computationally mapped isoform of Leucine rich repeats and calponin homology domain containing 2 OS=Gallus gallus OX=9031 GN=LRCH2 PE=4 SV=1 CANONICAL=A0A8V0Z782-1" }, "locus": { "chromosome": "4", "start_pos": 2854742, "end_pos": 2820304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045252.1", "url": "https://www.ensembl.org/id/ENSGALT00010045252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027018.1", "url": "https://www.ensembl.org/id/ENSGALP00010027018.1" } ] } }, { "isoform_ac": "A0A8V0Z782-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782/entry#A0A8V0Z782-1", "sequence": { "sequence": "MRSGGGGGGGRPRCCYCGAGLRRAKMAAGQGGGGGGNGGGSSNSSGGSSSNNNGTGGLGIPAHLTLSFSAGPHWGAATLPQPHTVRSLDRALEEAGSSGILCLSGRKLRDFPGSGYDLSDTTQADLSKNRFTEIPPDVWLFAPLETLNLYHNCIKSIPESIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLRDLMELDISCNELQVLPQQIGKLQSLRELNIRRNNLHMLPDELGDLPLVKLDFSCNKITEIPICYRKLRHLQVIVLDNNPMQIPPAQICLKGKVHIFKFLSIQACLRIDKKPDSLDLPSLGKRIPSQPLTDSIEDFYPNKNHGPDSGIGSDNGDKRLSTTEPSDDDTISLHSQVSESTREQTLRNDNHVMGNKLDPQKDQEVYDYIDPNAEEGAVPEQGDVQIGPLLSYIKERGKHPEKSQKIEHHEDWGDEKRLQKEQLLAEEDDEIKEVTDLRKIAAQLLQQEQKHRRRPLSYRTSFSEKLFQRTRAAGRASRLLNHSASVSTRNRPKQPVESEKCISTDEVNSPVSPYSWQPLENQKDSVDDQRWPETQPIIWQNEERRRSKQIRKEYFKYKSSRKSSSGNENDEDYERTDSNTHGPFGLKPRSAFSRAARQDYGAMDPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVPQERLCLPHHILEERGLVKVGLTVQALLELPTLKVSQLSAM", "length": 785, "header": "tr|A0A8V0Z782-1|A0A8V0Z782_CHICK Isoform 1 of Leucine rich repeats and calponin homology domain containing 2 OS=Gallus gallus OX=9031 GN=LRCH2 PE=4 SV=1 CANONICAL=A0A8V0Z782-1" }, "locus": { "chromosome": "4", "start_pos": 2854742, "end_pos": 2820304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045249.1", "url": "https://www.ensembl.org/id/ENSGALT00010045249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027015.1", "url": "https://www.ensembl.org/id/ENSGALP00010027015.1" } ] } }, { "isoform_ac": "A0A8V0Z8R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782/entry#A0A8V0Z8R9-1", "sequence": { "sequence": "MRSGGGGGGGRPRCCYCGAGLRRAKMAAGQGGGGGGNGGGSSNSSGGSSSNNNGTGGLGIPAHLTLSFSAGPHWGAATLPQPHTVRSLDRALEEAGSSGILCLSGRKLRDFPGSGYDLSDTTQADLSKNRFTEIPPDVWLFAPLETLNLYHNCIKSIPESIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLRDLMELDISCNELQVLPQQIGKLQSLRELNIRRNNLHMLPDELGDLPLVKLDFSCNKITEIPICYRKLRHLQVIVLDNNPMQIPPAQICLKGKVHIFKFLSIQACLRIDKKPDSLDLPSLGKRIPSQPLTDSSIEDFYPNKNHGPDSGIGSDNGDKRLSTTEPSDDDTISLHSQVSESTREQTLRNDNHVMGNKLDPQKDQEVYDYIDPNAEEGAVPEQGDVQIGPLLSYIKERGKHPEKSQKIEHHEDWGDEKRLQKEQLLAEEDDEIKEVTDLRKIAAQLLQQEQKHRLLNHSASVSTRNRPKQPVESEKCISTDEVNSPVSPYSWQPLENQKDSVDDQRWPETQPIIWQNEERRRSKQIRKEYFKYKSSRKSSSGNENDEQDSDNTNVSPQSPVSSEDYERTDSNTHGPFGLKPRSAFSRAARQDYGAMDPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVPQERLCLPHHILEERGLVKVGLTVQALLELPTLKVSQLSAM", "length": 777, "header": "tr|A0A8V0Z8R9-1|A0A8V0Z8R9_CHICK Computationally mapped isoform of Leucine rich repeats and calponin homology domain containing 2 OS=Gallus gallus OX=9031 GN=LRCH2 PE=4 SV=1 CANONICAL=A0A8V0Z782-1" }, "locus": { "chromosome": "4", "start_pos": 2854742, "end_pos": 2820304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045244.1", "url": "https://www.ensembl.org/id/ENSGALT00010045244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027011.1", "url": "https://www.ensembl.org/id/ENSGALP00010027011.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z782" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 662, "end_pos": 775, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z748-1", "uniprot_ac": "A0A8V0Z748", "uniprot_id": "A0A8V0Z748_CHICK", "mass": { "chemical_mass": 25288.0, "monoisotopic_mass": 25288.0 }, "refseq": {}, "gene_names": [ { "name": "CINP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ] } ], "protein_names": [ { "name": "Cyclin dependent kinase 2 interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CINP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748", "locus": { "chromosome": "5", "start_pos": 49097554, "end_pos": 49104595, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017208", "url": "https://www.ensembl.org/id/ENSGALG00010017208" } ] } } ], "crossref": [ { "id": "A0A8V0Z748", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z748", "database": "AlphaFoldDB", "categories": [] }, { "id": "423467", "url": "https://www.ncbi.nlm.nih.gov/gene/423467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1J3", "url": "https://www.orthodb.org/?gene=A0A8V0Z1J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z748", "url": "https://www.orthodb.org/?gene=A0A8V0Z748", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15827:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15827:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z748-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSMNFPFLSSIAKSPADGTPRRPVLSVSARKVKDNAADWHNLMMKWERLNDSGFTTANKIVNMKISEQLQDNKLEITCDNSTTESEKPSPKYNEELDNCCTELLETLKKMTKIQLKMEKLSSTTKGICDLEKFHHGGGSCAAPLFHTWPTAYFYEVSLKLSEMYKKELQLKQTIVQEIAHSADQDLMMVYLSSWLYQPYLDNSSKLLLEAMLLETGHRQC", "length": 221, "header": "tr|A0A8V0Z748-1|A0A8V0Z748_CHICK Isoform 1 of Cyclin dependent kinase 2 interacting protein OS=Gallus gallus OX=9031 GN=CINP PE=4 SV=1 CANONICAL=A0A8V0Z748-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748/entry#A0A8V0Z1J3-1", "sequence": { "sequence": "MAAKSPADGTPRRPVLSVSARKVKDNAADWHNLMMKWERLNDSGFTTANKIVNMKISEQLQDNKLEITCDNSTTESEKPSPKYNEELDNCCTELLETLKKMTKIQLKMEKLSSTTKGICDLEKFHHGGGSCAAPLFHTWPTAYFFAIEQKIAAKSSLQRFFEIQLIVTPEPSNAVIRQTVQKSSKKELLTAIKVSGRLTELCFAWYLHYLLCEVMTIITS", "length": 220, "header": "tr|A0A8V0Z1J3-1|A0A8V0Z748_CHICK Computationally mapped isoform of Cyclin dependent kinase 2 interacting protein OS=Gallus gallus OX=9031 GN=CINP PE=4 SV=1 CANONICAL=A0A8V0Z748-1" }, "locus": { "chromosome": "5", "start_pos": 49104579, "end_pos": 49097772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041492.1", "url": "https://www.ensembl.org/id/ENSGALT00010041492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024300.1", "url": "https://www.ensembl.org/id/ENSGALP00010024300.1" } ] } }, { "isoform_ac": "A0A8V0Z748-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748/entry#A0A8V0Z748-1", "sequence": { "sequence": "MFSMNFPFLSSIAKSPADGTPRRPVLSVSARKVKDNAADWHNLMMKWERLNDSGFTTANKIVNMKISEQLQDNKLEITCDNSTTESEKPSPKYNEELDNCCTELLETLKKMTKIQLKMEKLSSTTKGICDLEKFHHGGGSCAAPLFHTWPTAYFYEVSLKLSEMYKKELQLKQTIVQEIAHSADQDLMMVYLSSWLYQPYLDNSSKLLLEAMLLETGHRQC", "length": 221, "header": "tr|A0A8V0Z748-1|A0A8V0Z748_CHICK Isoform 1 of Cyclin dependent kinase 2 interacting protein OS=Gallus gallus OX=9031 GN=CINP PE=4 SV=1 CANONICAL=A0A8V0Z748-1" }, "locus": { "chromosome": "5", "start_pos": 49103979, "end_pos": 49099688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041489.1", "url": "https://www.ensembl.org/id/ENSGALT00010041489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024298.1", "url": "https://www.ensembl.org/id/ENSGALP00010024298.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "pmid": "" }, { "name": "regulation of ribosome biogenesis", "id": "GO:0090069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z748", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z748" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GFB3-1", "uniprot_ac": "R4GFB3", "uniprot_id": "R4GFB3_CHICK", "mass": { "chemical_mass": 135737.0, "monoisotopic_mass": 135737.0 }, "refseq": { "ac": "XP_015138973", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138973" }, "gene_names": [ { "name": "PLCB4", "type": "recommended", "evidence": [ { "id": "R4GFB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ] }, { "name": "PLCB4", "type": "synonym", "evidence": [ { "id": "XP_015138973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138973" } ] } ], "protein_names": [ { "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "type": "recommended", "evidence": [ { "id": "R4GFB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#names_and_taxonomy" } ] }, { "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015138973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138973" } ] }, { "name": "3.1.4.11", "type": "synonym", "evidence": [ { "id": "R4GFB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138973" } ] }, { "annotation": "Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development.", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3#function" }, { "database": "UniProtKB", "id": "ARBA00055176", "url": "https://www.uniprot.org/uniprotkb/ARBA00055176#function" }, { "database": "UniProtKB", "id": "A0A3Q2U0G2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0G2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S7#function" }, { "database": "UniProtKB", "id": "A0A8V0Z7D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7D8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA4#function" }, { "database": "UniProtKB", "id": "A0A3Q3AX15", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AX15#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLCB4", "url": "https://www.uniprot.org/uniprotkb/R4GFB3", "locus": { "chromosome": "3", "start_pos": 13654192, "end_pos": 13890095, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018418", "url": "https://www.ensembl.org/id/ENSGALG00010018418" } ] } } ], "crossref": [ { "id": "R4GFB3", "url": "https://alphafold.ebi.ac.uk/entry/R4GFB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008907", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13361", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13361", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416730", "url": "https://www.ncbi.nlm.nih.gov/gene/416730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416730", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMQKAHC", "url": "https://omabrowser.org/oma/group/AMQKAHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U0G2", "url": "https://www.orthodb.org/?gene=A0A3Q2U0G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AX15", "url": "https://www.orthodb.org/?gene=A0A3Q3AX15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5S7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7D8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GFB3", "url": "https://www.orthodb.org/?gene=R4GFB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112043", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112043", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "33179", "url": "https://www.rhea-db.org/rhea/33179", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43484", "url": "https://www.rhea-db.org/rhea/43484", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U0G2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U0G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U0G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AX15", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AX15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AX15-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AX15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFB3-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGLKPQHAN", "length": 1194, "header": "tr|R4GFB3-1|R4GFB3_CHICK Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U0G2-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#A0A3Q2U0G2-1", "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKIEVEAVEDSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGLKPQHAN", "length": 1210, "header": "tr|A0A3Q2U0G2-1|R4GFB3_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13745143, "end_pos": 13655894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044527.1", "url": "https://www.ensembl.org/id/ENSGALT00010044527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026506.1", "url": "https://www.ensembl.org/id/ENSGALP00010026506.1" } ] } }, { "isoform_ac": "A0A3Q3AX15-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#A0A3Q3AX15-1", "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVEDSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGLKPQHAN", "length": 1206, "header": "tr|A0A3Q3AX15-1|R4GFB3_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13745143, "end_pos": 13655894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044534.1", "url": "https://www.ensembl.org/id/ENSGALT00010044534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026509.1", "url": "https://www.ensembl.org/id/ENSGALP00010026509.1" } ] } }, { "isoform_ac": "A0A8V0Z5S7-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#A0A8V0Z5S7-1", "sequence": { "sequence": "MSESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVEDSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGLKPQHAN", "length": 1180, "header": "tr|A0A8V0Z5S7-1|R4GFB3_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13743523, "end_pos": 13655894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044509.1", "url": "https://www.ensembl.org/id/ENSGALT00010044509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026493.1", "url": "https://www.ensembl.org/id/ENSGALP00010026493.1" } ] } }, { "isoform_ac": "A0A8V0Z7D8-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#A0A8V0Z7D8-1", "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1175, "header": "tr|A0A8V0Z7D8-1|R4GFB3_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13745143, "end_pos": 13655914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044524.1", "url": "https://www.ensembl.org/id/ENSGALT00010044524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026504.1", "url": "https://www.ensembl.org/id/ENSGALP00010026504.1" } ] } }, { "isoform_ac": "A0A8V0ZDA4-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#A0A8V0ZDA4-1", "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVEDSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1187, "header": "tr|A0A8V0ZDA4-1|R4GFB3_CHICK Computationally mapped isoform of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13745143, "end_pos": 13655914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044522.1", "url": "https://www.ensembl.org/id/ENSGALT00010044522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026502.1", "url": "https://www.ensembl.org/id/ENSGALP00010026502.1" } ] } }, { "isoform_ac": "R4GFB3-1", "url": "https://www.uniprot.org/uniprotkb/R4GFB3/entry#R4GFB3-1", "sequence": { "sequence": "MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVLECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGIDLVNISFTFMVAENTEVAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKMMEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQSSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQALTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGLKPQHAN", "length": 1194, "header": "tr|R4GFB3-1|R4GFB3_CHICK Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Gallus gallus OX=9031 GN=PLCB4 PE=1 SV=1 CANONICAL=R4GFB3-1" }, "locus": { "chromosome": "3", "start_pos": 13745143, "end_pos": 13655894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044538.1", "url": "https://www.ensembl.org/id/ENSGALT00010044538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026510.1", "url": "https://www.ensembl.org/id/ENSGALP00010026510.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416730", "resource": "KEGG Pathway" }, { "id": "R-GGA-112043", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112043", "resource": "Reactome", "description": "PLC beta mediated events" }, { "id": "R-GGA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H217-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "Plcb4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPSCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRLAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMRIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPANILEDDNEEEIENADQEEEAHPEYKFGSELSADDFSHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNVHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSMKLQSAN", "length": 1194 }, "evidence": [ { "id": "R4GFB3", "url": "https://omabrowser.org/oma/group/R4GFB3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15147-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "gene_name": "PLCB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1175 }, "evidence": [ { "id": "R4GFB3", "url": "https://omabrowser.org/oma/group/R4GFB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QW07-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "gene_name": "Plcb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRLAAIPKDPKILAALESVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEITKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYQMSKYCEDLFGDLLLKQALESHPLEPGRLLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPASILEDDNEEEIESADQEEEAHPEYKFGNELSADDFSHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQLRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEIKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1175 }, "evidence": [ { "id": "R4GFB3", "url": "https://omabrowser.org/oma/group/R4GFB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "smooth endoplasmic reticulum", "id": "GO:0005790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005790", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "R4GFB3", "url": "https://www.uniprot.org/uniprotkb/R4GFB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33179", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBN2-1", "R4GFB3-1", "A0A8V0ZSL8-1", "A0A1D5NZL7-1", "A0A8V0YTH7-1", "A0A8V0ZCT0-1", "A0A8V0Z643-1", "A0A8V0ZKY1-1", "A0A8V0ZVU8-1", "A0A8V0XAT3-1", "A0A1D5PHP4-1", "A0A3Q2U9P4-1", "A0A8V0ZHR0-1", "A0A8V0ZUG3-1", "A0A8V1A5Y9-1", "Q2VRL0-1" ], "evidence": [ { "id": "33179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33179" } ] }, { "id": "43484", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A1D5NZL7-1", "A0A8V0ZKY1-1", "A0A8V0ZVU8-1", "A0A3Q2U9P4-1", "A0A8V0ZHR0-1" ], "evidence": [ { "id": "43484", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43484" } ] }, { "id": "R-GGA-111879", "name": "PIP2 hydrolysis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-111879", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111879" } ] }, { "id": "R-GGA-112037", "name": "Inactivation of PLC beta", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-112037", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112037" } ] }, { "id": "R-GGA-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1" ], "evidence": [ { "id": "R-GGA-114688", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114688" } ] }, { "id": "R-GGA-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GFB3-1", "A0A8V0ZVU8-1", "A0A1D5NZL7-1", "Q2VRL0-1" ], "evidence": [ { "id": "R-GGA-1855177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855177" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NZL7", "gene_name": "PLCB1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A1D5NZL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A1D5NZL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZL7" } ] } ] }, { "uniprot_ac": "A0A1D5PHP4", "gene_name": "PLCG2", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A1D5PHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHP4" } ] } ] }, { "uniprot_ac": "A0A3Q2U9P4", "gene_name": "PLCG1L", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A3Q2U9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P4" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A3Q2U9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P4" } ] } ] }, { "uniprot_ac": "A0A8V0XAT3", "gene_name": "PLCH1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0XAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAT3" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0XAT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAT3" } ] } ] }, { "uniprot_ac": "A0A8V0XBN2", "gene_name": "PLCL2", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0XBN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBN2" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0XBN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBN2" } ] } ] }, { "uniprot_ac": "A0A8V0YTH7", "gene_name": "PLCL1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0YTH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH7" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0YTH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH7" } ] } ] }, { "uniprot_ac": "A0A8V0Z643", "gene_name": "PLCE1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0Z643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z643" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0Z643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z643" } ] } ] }, { "uniprot_ac": "A0A8V0ZCT0", "gene_name": "PLCH2", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZCT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCT0" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZCT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCT0" } ] } ] }, { "uniprot_ac": "A0A8V0ZHR0", "gene_name": "PLCG1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR0" } ] } ] }, { "uniprot_ac": "A0A8V0ZKY1", "gene_name": "PLCD4", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY1" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY1" } ] } ] }, { 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"IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424542", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLV3", "url": "https://www.orthodb.org/?gene=A0A1D5PLV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA74", "url": "https://www.orthodb.org/?gene=A0A8V0ZA74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA79", "url": "https://www.orthodb.org/?gene=A0A8V0ZA79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH93", "url": "https://www.orthodb.org/?gene=A0A8V0ZH93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHA9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHB4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNC7", "url": "https://www.orthodb.org/?gene=A0A8V0ZNC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GIN8", "url": "https://www.orthodb.org/?gene=R4GIN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24353:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24353:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163615", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-164378", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-164378", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-180024", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-180024", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-392517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432040", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-442720", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610785", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610785", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5621575", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5621575", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5687128", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8963896", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8963896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9634597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9634597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLV3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIN8", "url": "https://www.uniprot.org/uniprotkb/R4GIN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIN8-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQKEVPCAQCTGTATALQRLEGFANRLFHRHSKGGAHDLRVPLENESHHVSELAVLWDKSMKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 398, "header": "tr|R4GIN8-1|R4GIN8_CHICK Isoform 1 of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=2 CANONICAL=R4GIN8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLV3-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A1D5PLV3-1", "sequence": { "sequence": "MNVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 338, "header": "tr|A0A1D5PLV3-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16403723, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050993.1", "url": "https://www.ensembl.org/id/ENSGALT00010050993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030184.1", "url": "https://www.ensembl.org/id/ENSGALP00010030184.1" } ] } }, { "isoform_ac": "A0A8V0ZA74-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZA74-1", "sequence": { "sequence": "MNETFVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 341, "header": "tr|A0A8V0ZA74-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16403723, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050994.1", "url": "https://www.ensembl.org/id/ENSGALT00010050994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030185.1", "url": "https://www.ensembl.org/id/ENSGALP00010030185.1" } ] } }, { "isoform_ac": "A0A8V0ZA79-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZA79-1", "sequence": { "sequence": "MSPGEWGRGRSGSGNVSRHSKGGAHDLRVPLENESHHVSELAVLWDKSKTFVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 387, "header": "tr|A0A8V0ZA79-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16434651, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050999.1", "url": "https://www.ensembl.org/id/ENSGALT00010050999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030190.1", "url": "https://www.ensembl.org/id/ENSGALP00010030190.1" } ] } }, { "isoform_ac": "A0A8V0ZFX7-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZFX7-1", "sequence": { "sequence": "MKDRKTQRVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 344, "header": "tr|A0A8V0ZFX7-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16397785, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050991.1", "url": "https://www.ensembl.org/id/ENSGALT00010050991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030182.1", "url": "https://www.ensembl.org/id/ENSGALP00010030182.1" } ] } }, { "isoform_ac": "A0A8V0ZH93-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZH93-1", "sequence": { "sequence": "MLAETFVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 342, "header": "tr|A0A8V0ZH93-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16434608, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050998.1", "url": "https://www.ensembl.org/id/ENSGALT00010050998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030189.1", "url": "https://www.ensembl.org/id/ENSGALP00010030189.1" } ] } }, { "isoform_ac": "A0A8V0ZHA9-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZHA9-1", "sequence": { "sequence": "MLAGVWLSRGSVVSLDMHSFPWGNETKTFVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 365, "header": "tr|A0A8V0ZHA9-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16434608, "end_pos": 16376059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050997.1", "url": "https://www.ensembl.org/id/ENSGALT00010050997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030188.1", "url": "https://www.ensembl.org/id/ENSGALP00010030188.1" } ] } }, { "isoform_ac": "A0A8V0ZHB4-1", "url": "https://www.uniprot.org/uniprotkb/R4GIN8/entry#A0A8V0ZHB4-1", "sequence": { "sequence": "MWCRNPVKEFLAKAKEDFLRKWESPPQNTAGLDDFERQKTLGTGSFGRVMMVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRASLTEKCAKEFADF", "length": 342, "header": "tr|A0A8V0ZHB4-1|R4GIN8_CHICK Computationally mapped isoform of cAMP-dependent protein kinase OS=Gallus gallus OX=9031 GN=PRKACB PE=1 SV=1 CANONICAL=R4GIN8-1" }, "locus": { "chromosome": "8", "start_pos": 16392872, "end_pos": 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"A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-111925", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111925" } ] }, { "id": "R-GGA-177275", "name": "PKA phosphorylates DARPP-32 on Thr34", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-GGA-177274" ], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-177275", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-177275" } ] }, { "id": "R-GGA-177284", "name": "PKA phosphorylates PDE4B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-9822899" ], "output_participant_list": [ "R-GGA-9822883" ], "enzyme_list": [ "A0A8V1A706-1", "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-177284", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-177284" } ] }, { "id": "R-GGA-265682", "name": "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-265682", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-265682" } ] }, { "id": "R-GGA-381644", "name": "ER calcium channels open in response to activated PKA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-381644", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381644" } ] }, { "id": "R-GGA-381713", "name": "Potassium voltage-gated channels close in reponse to PKA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-381713", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381713" } ] }, { "id": "R-GGA-432232", "name": "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, transport vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-432232", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432232" } ] }, { "id": "R-GGA-5610720", "name": "PKA phosphorylates GLI3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "ciliary base", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-5610720", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610720" } ] }, { "id": "R-GGA-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "ciliary base", "input_participant_list": [], "output_participant_list": [ "R-GGA-5610404" ], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-5610749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610749" } ] }, { "id": "R-GGA-5624473", "name": "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F3L1-1", "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-5624473", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624473" } ] }, { "id": "R-GGA-5682101", "name": "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUL4-1", "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-5682101", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5682101" } ] }, { "id": "R-GGA-5687088", "name": "PKA phosphorylates MAPKAPK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-2562517" ], "output_participant_list": [ "R-GGA-5687026" ], "enzyme_list": [ "A0A8V1A4J8-1", "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-5687088", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5687088" } ] }, { "id": "R-GGA-8951727", "name": "cAMP binds PKA tetramer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-8951727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951727" } ] }, { "id": "R-GGA-913996", "name": "PKA/PKG phosphorylate Rap1GAP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-392491" ], "output_participant_list": [ "R-GGA-913989" ], "enzyme_list": [ "A0A8V0ZXQ9-1", "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-913996", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913996" } ] }, { "id": "R-GGA-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GIN8-1" ], "evidence": [ { "id": "R-GGA-992708", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-992708" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-177274", "participant_name": "phospho-PPP1R1B [cytosol]", "crossref": [ { "id": "ENSGALG00010024327", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010059324", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0ZZ77", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010036210", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-2562517", "participant_name": "MAPKAPK5 [nucleoplasm]", "crossref": [ { "id": "A0A8V1A4J8", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010025897", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010038970", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010063129", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-392491", "participant_name": "RAP1GAP2 [cytosol]", "crossref": [ { "id": "A0A8V1AJ27", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010029255", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010043417", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010070726", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5610404", "participant_name": "PRKACB [ciliary base]", "crossref": [ { "id": "ENSGALG00010021072", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010050996", "database": "ENSEMBL", "url": "" }, { "id": "R4GIN8", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010030187", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5687026", "participant_name": "phospho-MAPKAPK5 [nucleoplasm]", "crossref": [ { "id": "ENSGALG00010025897", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010063129", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A4J8", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010038970", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-913989", "participant_name": "phospho-RAP1GAP2 [cytosol]", "crossref": [ { "id": "ENSGALG00010029255", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010070726", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010043417", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1AJ27", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-GGA-9822883", "participant_name": "phospho-p-S54-PDE4B-3 [cytosol]", "crossref": [ { "id": "ENSGALG00010027081", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065639", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A706", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010039905", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-9822899", "participant_name": "PDE4B-3 [cytosol]", "crossref": [ { "id": "A0A8V1A706", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027081", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010039905", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010065639", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YUL4", "gene_name": "ABCA1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A8V0YUL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL4" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YUL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL4" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A706", "gene_name": "PDE4B", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "A0A8V1A706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A706" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003642058.1. 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416036", "url": "https://www.ncbi.nlm.nih.gov/gene/416036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416036", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEDEWKW", "url": "https://omabrowser.org/oma/group/SEDEWKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIJ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZIJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P486", "url": "https://www.orthodb.org/?gene=F1P486", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642058", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P486-1", "url": "https://www.uniprot.org/uniprotkb/F1P486-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHKGIMLIVFLECFISGHGEADPVRLRAFRCSGRSCNPPVGNLATGRTPITLTTCGQNSTELYCSYPDQSLLHPASHGCGQPRCTKCNANQPDNSHLPADMTDDFFANPVSWWQSAQGVHREEIRLDFETEFYLTHVIAVFKSPRPAAMVLERSQDYGQTWRPYKYFSVNCTATFGLQDDLTEEGSMCTSRYSDAVPCTRGEVIYRALTPSNKIEDPYSPEAQDLLKLTNLRLLLLKRQECPCRGLGLVEKPQRFAHYAIYDLIIRGSCFCNGHAEECELANRTGEVENVVHGKCVCRHNTAGDHCEKCAPLYNDQPWKPGDGKTGAPNECKKCRCHNHADSCHFDLSVWLASGKRSGGVCDNCKHNTEGHRCQRCKPGYYRDRGKPMSSAEVCKPCSCQPMGSANATFSRSWRCHPKTGFCYCKPGVAGPNCDRCLMGYWGFGENGCRPCDCARDCDQHTGNCFNSYDNEPFFNIPIGGRIPDLVQTPTNESEDEWKWNDHEQGFSALRHPEKCVCKEKVLGSVNDFCQMKYAYVIKARILSAHDKGTHAEVVVKVKKVLKSSKVKIARSNRSIYPESWTNRGCTCPILNPGTDYLIAGQEDSRSSKLLVNMNSLVKPWKAHLGKQVADILRTGCK", "length": 638, "header": "tr|F1P486-1|F1P486_CHICK Isoform 1 of Netrin-4 OS=Gallus gallus OX=9031 GN=NTN4L PE=4 SV=5 CANONICAL=F1P486-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBH0-1", "url": "https://www.uniprot.org/uniprotkb/F1P486/entry#A0A8V0ZBH0-1", "sequence": { "sequence": "MPYDLSPIGYTTEDPVRLRAFRCSGRSCNPPVGNLATGRTPITLTTCGQNSTELYCSYPDQSLLHPASHGCGQPRCTKCNANQPDNSHLPADMTDDFFANPVSWWQSAQGVHREEIRLDFETEFYLTHVIAVFKSPRPAAMVLERSQDYGQTWRPYKYFSVNCTATFGLQDDLTEEGSMCTSRYSDAVPCTRGEVIYRALTPSNKIEDPYSPEAQDLLKLTNLRLLLLKRQECPCRGLGLVEKPQRFAHYAIYDLIIRGSCFCNGHAEECELANRTGEVENVVHGKCVCRHNTAGDHCEKCAPLYNDQPWKPGDGKTGAPNECKKCRCHNHADSCHFDLSVWLASGKRSGGVCDNCKHNTEGHRCQRCKPGYYRDRGKPMSSAEVCKPCSCQPMGSANATFSRSWRCHPKTGFCYCKPGVAGPNCDRCLMGYWGFGENGCRPCDCARDCDQHTGNCFNSYDNEPFFNIPIGGRIPDLVQTPTNESEDEWKWNDHEQGFSALRHPEKCVCKEKVLGSVNDFCQMKYAYVIKARILSAHDKGTHAEVVVKVKKVLKSSKVKIARSNRSIYPESWTNRGCTCPILNPGTDYLIAGQEDSRSSKLLVNMNSLVKPWKAHLGKQVADILRTGCK", "length": 629, "header": "tr|A0A8V0ZBH0-1|A0A8V0ZBH0_CHICK Computationally mapped isoform of Netrin-4 OS=Gallus gallus OX=9031 GN=NTN4L PE=4 SV=1 CANONICAL=F1P486-1" }, "locus": { "chromosome": "12", "start_pos": 10941357, "end_pos": 10902614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051430.1", "url": "https://www.ensembl.org/id/ENSGALT00010051430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030621.1", "url": "https://www.ensembl.org/id/ENSGALP00010030621.1" } ] } }, { "isoform_ac": "A0A8V0ZIJ4-1", "url": "https://www.uniprot.org/uniprotkb/F1P486/entry#A0A8V0ZIJ4-1", "sequence": { "sequence": "MQHKGIMLIVFLECFISGHGEADPVRLRAFRCSGRSCNPPVGNLATGRTPITLTTCGQNSTELYCSYPDQSLLHPASHGCGQPRCTKCNANQPDNSHLPADMTDDFFANPVSWWQSAQGVHREEIRLDFETEFYLTHVIAVFKSPRPAAMVLERSQDYGQTWRPYKYFSVNCTATFGLQDDLTEEGSMCTSRYSDAVPCTRGEVIYRALTPSNKIEDPYSPEAQDLLKLTNLRLLLLKRQECPCRGLGLVEKPQRFAHYAIYDLIIRGSCFCNGHAEECELANRTGEVENVVHGKCVCRHNTAGDHCEKCAPLYNDQPWKPGDGKTGAPNECKKCRCHNHADSCHFDLSVWLASGKRSGGVCDNCKHNTEGHRCQRCKPGYYRDRGKPMSSAEVCKPCSCQPMGSANATFSRSWRCHPKTGFCYCKPGVAGPNCDRCLMGYWGFGENGCRPCDCARDCDQHTGNCFNSYDNEPFFNIPIGGRIPDLVQTPTNESEDEWKWNDHEQGFSALRHPEKCVCKEKVLGSVNDFCQMKYAYGNFLTSSCGADHPFPLDTNLESPVLKLYQFKTSFQAVKYKAQNQRASNETISS", "length": 589, "header": "tr|A0A8V0ZIJ4-1|A0A8V0ZIJ4_CHICK Computationally mapped isoform of Netrin-4 OS=Gallus gallus OX=9031 GN=NTN4L PE=4 SV=1 CANONICAL=F1P486-1" }, "locus": { "chromosome": "12", "start_pos": 10938921, "end_pos": 10899992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051428.1", "url": "https://www.ensembl.org/id/ENSGALT00010051428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030619.1", "url": "https://www.ensembl.org/id/ENSGALP00010030619.1" } ] } }, { "isoform_ac": "A0A8V0ZIJ9-1", "url": "https://www.uniprot.org/uniprotkb/F1P486/entry#A0A8V0ZIJ9-1", "sequence": { "sequence": "MQHKGIMLIVFLECFISGHGEADPVRLRAFRCSGRSCNPPVGNLATGRTPITLTTCGQNSTELYCSYPDQSLLHPASHGCGQPRCTKCNANQPDNSHLPADMTDDFFANPVSWWQSAQGVHREEIRLDFETEFYLTHVIAVFKSPRPAAMVLERSQDYGQTWRPYKYFSVNCTATFGLQDDLTEEGSMCTSRYSDAVPCTRGEVIYRALTPSNKIEDPYSPEAQDLLKLTNLRLLLLKRQECPCRGLGLVEKPQRFAHYAIYDLIIRGSCFCNGHAEECELANRTGEVENVVHGKCVCRHNTAGDHCEKCAPLYNDQPWKPGDGKTGAPNECKKCRCHNHADSCHFDLSVWLASGKRSGGVCDNCKHNTEGHRCQRCKPGYYRDRGKPMSSAEVCKPCSCQPMGSANATFSRSWRCHPKTGFCYCKPGVAGPNCDRCLMGYWGFGENGCRPCDCARDCDQHTGNCFNSYDNEPFFNIPIGGRIPDLVQTPTNESEDEWKWNDHEQGFSALRHPVIKARILSAHDKGTHAEVVVKVKKVLKSSKVKIARSNRSIYPESWTNRGCTCPILNPGTDYLIAGQEDSRSSKLLVNMNSLVKPWKAHLGKQVADILRTGCK", "length": 615, "header": "tr|A0A8V0ZIJ9-1|F1P486_CHICK Computationally mapped isoform of Netrin-4 OS=Gallus gallus OX=9031 GN=NTN4L PE=4 SV=1 CANONICAL=F1P486-1" }, "locus": { "chromosome": "12", "start_pos": 10941357, "end_pos": 10899992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051433.1", "url": "https://www.ensembl.org/id/ENSGALT00010051433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030624.1", "url": "https://www.ensembl.org/id/ENSGALP00010030624.1" } ] } }, { "isoform_ac": "F1P486-1", "url": "https://www.uniprot.org/uniprotkb/F1P486/entry#F1P486-1", "sequence": { "sequence": "MQHKGIMLIVFLECFISGHGEADPVRLRAFRCSGRSCNPPVGNLATGRTPITLTTCGQNSTELYCSYPDQSLLHPASHGCGQPRCTKCNANQPDNSHLPADMTDDFFANPVSWWQSAQGVHREEIRLDFETEFYLTHVIAVFKSPRPAAMVLERSQDYGQTWRPYKYFSVNCTATFGLQDDLTEEGSMCTSRYSDAVPCTRGEVIYRALTPSNKIEDPYSPEAQDLLKLTNLRLLLLKRQECPCRGLGLVEKPQRFAHYAIYDLIIRGSCFCNGHAEECELANRTGEVENVVHGKCVCRHNTAGDHCEKCAPLYNDQPWKPGDGKTGAPNECKKCRCHNHADSCHFDLSVWLASGKRSGGVCDNCKHNTEGHRCQRCKPGYYRDRGKPMSSAEVCKPCSCQPMGSANATFSRSWRCHPKTGFCYCKPGVAGPNCDRCLMGYWGFGENGCRPCDCARDCDQHTGNCFNSYDNEPFFNIPIGGRIPDLVQTPTNESEDEWKWNDHEQGFSALRHPEKCVCKEKVLGSVNDFCQMKYAYVIKARILSAHDKGTHAEVVVKVKKVLKSSKVKIARSNRSIYPESWTNRGCTCPILNPGTDYLIAGQEDSRSSKLLVNMNSLVKPWKAHLGKQVADILRTGCK", "length": 638, "header": "tr|F1P486-1|F1P486_CHICK Isoform 1 of Netrin-4 OS=Gallus gallus OX=9031 GN=NTN4L PE=4 SV=5 CANONICAL=F1P486-1" }, "locus": { "chromosome": "12", "start_pos": 10941357, "end_pos": 10899992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051432.1", "url": "https://www.ensembl.org/id/ENSGALT00010051432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030623.1", "url": "https://www.ensembl.org/id/ENSGALP00010030623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416036", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "laminin complex", "id": "GO:0043256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043256", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" }, { "name": "basement membrane assembly", "id": "GO:0070831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070831", "evidence": [ { "database": "UniProtKB", "id": "F1P486", "url": "https://www.uniprot.org/uniprotkb/F1P486" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P486-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 638, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P486-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P486" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJ83-1", "uniprot_ac": "R4GJ83", "uniprot_id": "R4GJ83_CHICK", "mass": { "chemical_mass": 44107.0, "monoisotopic_mass": 44107.0 }, "refseq": { "ac": "XP_003642500", "name": "endoplasmic reticulum-Golgi intermediate compartment protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642500" }, "gene_names": [ { "name": "ERGIC3", "type": "recommended", "evidence": [ { "id": "R4GJ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ] }, { "name": "ERGIC3", "type": "synonym", "evidence": [ { "id": "XP_003642500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642500" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "type": "recommended", "evidence": [ { "id": "R4GJ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJ83/entry#names_and_taxonomy" } ] }, { "name": "endoplasmic reticulum-Golgi intermediate compartment protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642500" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642500" } ] }, { "annotation": "Plays a role in transport between endoplasmic reticulum and Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ3#function" }, { "database": "UniProtKB", "id": "RU369013", "url": "https://www.uniprot.org/uniprotkb/RU369013#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW6#function" }, { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERGIC3", "url": "https://www.uniprot.org/uniprotkb/R4GJ83", "locus": { "chromosome": "20", "start_pos": 1497211, "end_pos": 1521566, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021970", "url": "https://www.ensembl.org/id/ENSGALG00010021970" } ] } } ], "crossref": [ { "id": "R4GJ83", "url": "https://alphafold.ebi.ac.uk/entry/R4GJ83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027834", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027834", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419137", "url": "https://www.ncbi.nlm.nih.gov/gene/419137", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QRHEGCR", "url": "https://omabrowser.org/oma/group/QRHEGCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMZ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJ83", "url": "https://www.orthodb.org/?gene=R4GJ83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10984:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10984:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJ83-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLWRLKRFDAFPKTLEDFRVKTCGGALVTVVSGLIMVLLFFSELQYYLTKEVHPELYVDKSRGDKLKINIDVVFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKAGNRVTPEAERHELGKEEEKVFDPNSLDADRCESCYGAESEDIRCCNTCDDVREAYRRRGWAFKNPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSFGLDNINMTHYIKHLSFGRDYPGIVNPLDGTDVTAQQASMMFQYFVKVVPTVYMKVDGEVVRTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMVKLTEKHRPFTHFLTGVCAIVGGIFTVAGFIDSLIYHSARAIQKKIELGKTI", "length": 388, "header": "tr|R4GJ83-1|R4GJ83_CHICK Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Gallus gallus OX=9031 GN=ERGIC3 PE=1 SV=2 CANONICAL=R4GJ83-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFW6-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ83/entry#A0A8V0ZFW6-1", "sequence": { "sequence": "MESLWRLKRFDAFPKTLEDFRVKTCGGALVTVVSGLIMVLLFFSELQYYLTKEVHPELYVDKSRGDKLKINIDVVFPHMPYLSIDAMDVAGEQQLDVEHNLFKQRLDKAGNRVTPEAERHELGKEEEKVFDPNSLDADRCESCYGAESEDIRCCNTCDDVREAYRRRGWAFKNPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIKHLSFGRDYPGIVNPLDGTDVTAQQASMMFQYFVKVVPTVYMKVDGEVVRTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMVKLTEKHRPFTHFLTGVCAIVGGIFTVAGFIDSLIYHSARAIQKKIELGKTI", "length": 381, "header": "tr|A0A8V0ZFW6-1|R4GJ83_CHICK Computationally mapped isoform of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Gallus gallus OX=9031 GN=ERGIC3 PE=1 SV=1 CANONICAL=R4GJ83-1" }, "locus": { "chromosome": "20", "start_pos": 1521535, "end_pos": 1498016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053424.1", "url": "https://www.ensembl.org/id/ENSGALT00010053424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032200.1", "url": "https://www.ensembl.org/id/ENSGALP00010032200.1" } ] } }, { "isoform_ac": "A0A8V0ZMZ3-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ83/entry#A0A8V0ZMZ3-1", "sequence": { "sequence": "MESLWRLKRFDAFPKTLEDFRVKTCGGALVTVVSGLIMVLLFFSELQYYLTKEVHPELYVDKSRGDKLKINIDVVFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKAGNRVTPEAERHELGKEEEKVFDPNSLDADRCESCYGAESEDIRCCNTCDDVREAYRRRGWAFKNPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKLEIFTLHQEKASSNLMYMINMTHYIKHLSFGRDYPGIVNPLDGTDVTAQQASMMFQYFVKVVPTVYMKVDGEVVRTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMVKLTEKHRPFTHFLTGVCAIVGGIFTVAGFIDSLIYHSARAIQKKIELGKTI", "length": 371, "header": "tr|A0A8V0ZMZ3-1|R4GJ83_CHICK Computationally mapped isoform of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Gallus gallus OX=9031 GN=ERGIC3 PE=1 SV=1 CANONICAL=R4GJ83-1" }, "locus": { "chromosome": "20", "start_pos": 1521535, "end_pos": 1498016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053411.1", "url": "https://www.ensembl.org/id/ENSGALT00010053411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032194.1", "url": "https://www.ensembl.org/id/ENSGALP00010032194.1" } ] } }, { "isoform_ac": "A0A8V0ZTN6-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ83/entry#A0A8V0ZTN6-1", "sequence": { "sequence": "MESLWRLKRFDAFPKTLEDFRVKTCGGALVTVVSGLIMVLLFFSELQYYLTKEVHPELYVDKSRGDKLKINIDVVFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKAGNRVTPEAERHELGKEEEKVFDPNSLDADRCESCYGAESEDIRCCNTCDDVREAYRRRGWAFKNPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIKHLSFGRDYPGIVNPLDGTDVTAQQASMMFQYFVKVVPTVYMKVDGEVVRTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMGVLSVPCGPPFVSDCPS", "length": 348, "header": "tr|A0A8V0ZTN6-1|R4GJ83_CHICK Computationally mapped isoform of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Gallus gallus OX=9031 GN=ERGIC3 PE=1 SV=1 CANONICAL=R4GJ83-1" }, "locus": { "chromosome": "20", "start_pos": 1521535, "end_pos": 1497447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053418.1", "url": "https://www.ensembl.org/id/ENSGALT00010053418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032196.1", "url": "https://www.ensembl.org/id/ENSGALP00010032196.1" } ] } }, { "isoform_ac": "R4GJ83-1", "url": "https://www.uniprot.org/uniprotkb/R4GJ83/entry#R4GJ83-1", "sequence": { "sequence": "MESLWRLKRFDAFPKTLEDFRVKTCGGALVTVVSGLIMVLLFFSELQYYLTKEVHPELYVDKSRGDKLKINIDVVFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKAGNRVTPEAERHELGKEEEKVFDPNSLDADRCESCYGAESEDIRCCNTCDDVREAYRRRGWAFKNPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSFGLDNINMTHYIKHLSFGRDYPGIVNPLDGTDVTAQQASMMFQYFVKVVPTVYMKVDGEVVRTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMVKLTEKHRPFTHFLTGVCAIVGGIFTVAGFIDSLIYHSARAIQKKIELGKTI", "length": 388, "header": "tr|R4GJ83-1|R4GJ83_CHICK Isoform 1 of Endoplasmic reticulum-Golgi intermediate compartment protein OS=Gallus gallus OX=9031 GN=ERGIC3 PE=1 SV=2 CANONICAL=R4GJ83-1" }, "locus": { "chromosome": "20", "start_pos": 1521535, "end_pos": 1498016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053429.1", "url": "https://www.ensembl.org/id/ENSGALT00010053429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032205.1", "url": "https://www.ensembl.org/id/ENSGALP00010032205.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A0W6-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "gene_name": "ERGIC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAERHELGKVEIKVFDPDSLDPDRCESCYGAETEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDRTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVASGLMGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 388 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZU83-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "gene_name": "Ergic3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAGLIAFEKASEGWSPTYALLRLRKTARGVTPTSGRKREAGGAGRLVSPFRPVPMEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKKRLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPNRCESCYGAESEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSFGLDNINMTHYIKHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 443 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HAQ9-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "gene_name": "Ergic3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVIFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKKRLDKDGIPVSSEAERHELGKVEVAVFDPNSLDPNRCESCYGAESDDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIKHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P39727-1", "protein_name": "ER-derived vesicles protein ERV46", "gene_name": "ERV46", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKRSTLLSLDAFAKTEEDVRVRTRAGGLITLSCILTTLFLLVNEWGQFNSVVTRPQLVVDRDRHAKLELNMDVTFPSMPCDLVNLDIMDDSGEMQLDILDAGFTMSRLNSEGRPVGDATELHVGGNGDGTAPVNNDPNYCGPCYGAKDQSQNENLAQEEKVCCQDCDAVRSAYLEAGWAFFDGKNIEQCEREGYVSKINEHLNEGCRIKGSAQINRIQGNLHFAPGKPYQNAYGHFHDTSLYDKTSNLNFNHIINHLSFGKPIQSHSKLLGNDKRHGGAVVATSPLDGRQVFPDRNTHFHQFSYFAKIVPTRYEYLDNVVIETAQFSATFHSRPLAGGRDKDHPNTLHVRGGIPGMFVFFEMSPLKVINKEQHGQTWSGFILNCITSIGGVLAVGTVMDKLFYKAQRSIWGKKSQ", "length": 415 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54DW2-1", "protein_name": "Probable endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "ergic3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLISQLKKFDAYPKTVDDFRVKTYTGAIVSIIGGVFILWLFFSQVTLYFSTDIHHELFVDTTRGEKLKINMDITFHHLPCAYLSLDAMDVSGEHQFDVAHNIFKKRLSPTGQPIIEAPPIREEEINKKESVKDNNDVVGCGSCYGAEDPSKGIGCCNTCEEVRVAYSKKGWGLDPSGIPQCIREGFTKNLVEQNGEGCQVYGFILVNKVAGNFHFAPGKSFQQHHMHVHDLQPFKDGSFNVSHTINRLSFGNDFPGIKNPLDDVTKTEMVGVGMFQYFVKVVPTIYEGLNGNRIATNQYSVTEHYRLLAKKGEEPSGLPGLFFMYDLSPIMMKVSERGKSFASFLTNVCAIIGGVFTVFGIFDSFIYYSTKNLQKKIDLGKTF", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAE0-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "ERGIC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKININVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKKRLDKDGFPVSSEAERHELGKVEVKVFDPDSLDPDRCESCYGAEMEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIRHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLMGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q803I2-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "ergic3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDALNKLKQFDAYPKTLEDFRIKTCGGATVTIISGLIMLILFFSELQYYLTKEVHPELFVDTSRGDKLRINIDVIFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGQPVTTEAEKHDLGKEEEGVFDPSTLDPDRCESCYGAETDDLKCCNTCDDVREAYRRRGWAFKTPDTIEQCKREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHFIKHLSFGKDYPGIVNPLDDTNVAAPQASMMYQYFVKIVPTIYVKGDGEVVKTNQFSVTRHEKIANGLIGDQGLPGVFVLYELSPMMVKFTEKQRSFTHFLTGVCAIIGGVFTVAGLIDSLIYHSARAIQKKIELGKAS", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9C8W1-1", "protein_name": "Endoplasmic reticulum vesicle transporter protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGILNKLRNLDAYPKINEDFYSRTLSGGVITLLSSVVMFLLFFSELRLYLHTVTETKLIVDTSRGETLRINFDITFPALACSILSVDAMDISGELHLDVKHDIIKRRLDSNGNTIEARQDGIGATKIENPLQKHGGRLGHNETYCGSCYGAEAEEHDCCNSCEDVREAYRKKGWGVTNPDLIDQCKREGFLQRVKDEEGEGCNIYGFLEVNKVAGNFHFAPGKSFHQSGVHVHDLLAFQKDSFNISHKINRLTYGDYFPGVVNPLDKVEWSQDTPNAMYQYFIKVVPTVYTDIRGHTIQSNQFSVTEHVKSSEAGQLQSLPGVFFFYDLSPIKVTFTEEHISFLHFLTNVCAIVGGVFTVSGIIDAFIYHGQKAIKKKMEIGKFS", "length": 386 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQE7-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "Ergic3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKKRLDKDGVPVSSEAERHELGKVEVTVFDPNSLDPNRCESCYGAESEDIKCCNSCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIKHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VUM3-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "Dmel\\CG7011", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFADVLRRLDAYPRTLDDFSVRTVGGAAVTIISTSIISLLIFLEVLNYMQPTLNEELFVDTTRDHKLRINLDVTLHNLACNYISLDAMDSSGDTHLRVDHDVFKHRLDLNGEPLKETPIKEIVAVSPPNKNVTCGSCYGAEHNATHCCNTCEDVLDAYRLRKWTVAVDKIEQCKGKYKRSDEDAFKEGCRIQGHLEVNRMAGSFHFAPGKSFSIRQFHIHDFQFSNVKLSHTINHLSFGEKIEFAKTHPLDGLRVDVAETKSEMFNYYLKIVPTLYMRGNSDGEPIYTNQFSVTRYRKDLSDRERGMPGIFFSYELSPLMVKYAERHSSFGHFATNCCSIIGGVFTVAGILAVLLNNSWEAIQRKLEVGKLS", "length": 373 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y282-1", "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "ERGIC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVDKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAERHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLIDSLIYHSARAIQKKIDLGKTT", "length": 383 }, "evidence": [ { "id": "R4GJ83", "url": "https://omabrowser.org/oma/group/R4GJ83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "R4GJ83", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GJ83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 388, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GJ83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GJ83" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GJ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" }, { "id": "PF07970", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07970" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum vesicle transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 368, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "R4GJ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJ83" }, { "id": "PF13850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum vesicle transporter N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 97, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6VMN5-1", "uniprot_ac": "F6VMN5", "uniprot_id": "F6VMN5_CHICK", "mass": { "chemical_mass": 39415.0, "monoisotopic_mass": 39415.0 }, "refseq": { "ac": "NP_001264423", "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" }, "gene_names": [ { "name": "ST6GALNAC5", "type": "recommended", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ] }, { "name": "SIAT7E", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] }, { "name": "ST6GALNAC5", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] } ], "protein_names": [ { "name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5", "type": "recommended", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#names_and_taxonomy" } ] }, { "name": "GD1 alpha synthase", "type": "synonym", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#names_and_taxonomy" } ] }, { "name": "GalNAc alpha-2,6-sialyltransferase V", "type": "synonym", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#names_and_taxonomy" } ] }, { "name": "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] }, { "name": "ST6GalNAc V", "type": "synonym", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase 7E", "type": "synonym", "evidence": [ { "id": "F6VMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#names_and_taxonomy" } ] }, { "name": "alpha-2,6-sialyltransferase ST6GalNAc V", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] }, { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] }, { "name": "sialyltransferase 7E", "type": "synonym", "evidence": [ { "id": "NP_001264423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ646877.1, SRR13267649.120620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992482 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Apr 11, 2013 this sequence version replaced XP_422393.1. Sequence Note: This RefSeq record was created from genomic sequence and transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264423", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423" } ] }, { "annotation": "Predominantly catalyzes the biosynthesis of ganglioside GD1alpha from GM1b in the brain, by transferring the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of GM1b. GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis. Also shows activity towards sialyl Lc4Cer (N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine) generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen.", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5#function" }, { "database": "UniProtKB", "id": "ARBA00056921", "url": "https://www.uniprot.org/uniprotkb/ARBA00056921#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST6GALNAC5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5", "locus": { "chromosome": "8", "start_pos": 18942921, "end_pos": 19009559, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022471", "url": "https://www.ensembl.org/id/ENSGALG00010022471" } ] } } ], "crossref": [ { "id": "F6VMN5", "url": "https://alphafold.ebi.ac.uk/entry/F6VMN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009021", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23976", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23976", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "407778", "url": "https://www.ncbi.nlm.nih.gov/gene/407778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:407778", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:407778", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6VMN5", "url": "https://www.orthodb.org/?gene=F6VMN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264423", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41968", "url": "https://www.rhea-db.org/rhea/41968", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47884", "url": "https://www.rhea-db.org/rhea/47884", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6VMN5-1", "url": "https://www.uniprot.org/uniprotkb/F6VMN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLAGSGRSGAREAHKMKTLMRHGLAVCLALTTMCTSLLLMYGGIGGGGGGHPEPRRRQQQQQQVAAVPSRPPGRGQHRPALPVGAGLLEGYISVLEHKPLKMHCKSCALVTSSGHLLGSKQGDRIDETECVIRMNDAPTRGYGQDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKAYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFNIHFFQPDWKPEPLTVNHPEMKAAV", "length": 349, "header": "tr|F6VMN5-1|F6VMN5_CHICK Isoform 1 of Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 OS=Gallus gallus OX=9031 GN=ST6GALNAC5 PE=3 SV=1 CANONICAL=F6VMN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNJ4-1", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#A0A8V0ZNJ4-1", "sequence": { "sequence": "MPSLAGSGRSGAREAHKMKTLMRHGLAVCLALTTMCTSLLLMYGGIGGGGGGHPEPRRRQQQQQQVAAVPSRPPGRGQHRPALPVGAGLLEGYISVLEHKPLKMHCKSCALVTSSGHLLGSKQGDRIDETECVIRMNDAPTRGYGQDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKAYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCSWQRRISSVPVLKRLCPCHHCKWLVCLSHLKIQWRGAGFGVLMDRKLDMSQQCAPAAQKASCTLGCIN", "length": 340, "header": "tr|A0A8V0ZNJ4-1|F6VMN5_CHICK Computationally mapped isoform of Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 OS=Gallus gallus OX=9031 GN=ST6GALNAC5 PE=3 SV=1 CANONICAL=F6VMN5-1" }, "locus": { "chromosome": "8", "start_pos": 19009425, "end_pos": 18950074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054664.1", "url": "https://www.ensembl.org/id/ENSGALT00010054664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033024.1", "url": "https://www.ensembl.org/id/ENSGALP00010033024.1" } ] } }, { "isoform_ac": "F6VMN5-1", "url": "https://www.uniprot.org/uniprotkb/F6VMN5/entry#F6VMN5-1", "sequence": { "sequence": "MPSLAGSGRSGAREAHKMKTLMRHGLAVCLALTTMCTSLLLMYGGIGGGGGGHPEPRRRQQQQQQVAAVPSRPPGRGQHRPALPVGAGLLEGYISVLEHKPLKMHCKSCALVTSSGHLLGSKQGDRIDETECVIRMNDAPTRGYGQDVGNKTSLRVIAHSSIQRILRNRNELLNMSHGAVFIFWGPSSYMRRDGKGLVYNNLQLMNQILPQLKAYMISRHKMLQFDDLFKRETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHLSVPYHYYEPLGPDECTMYISHERGRKGSHHRFITEKRVFENWARTFNIHFFQPDWKPEPLTVNHPEMKAAV", "length": 349, "header": "tr|F6VMN5-1|F6VMN5_CHICK Isoform 1 of Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 OS=Gallus gallus OX=9031 GN=ST6GALNAC5 PE=3 SV=1 CANONICAL=F6VMN5-1" }, "locus": { "chromosome": "8", "start_pos": 19009425, "end_pos": 18944202, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054669.1", "url": "https://www.ensembl.org/id/ENSGALT00010054669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033031.1", "url": "https://www.ensembl.org/id/ENSGALP00010033031.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:407778", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:407778", "resource": "KEGG Pathway" }, { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-GGA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" }, { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "F6VMN5", "url": "https://www.uniprot.org/uniprotkb/F6VMN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41968", "name": "", "equation": "a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZY98-1", "A0A8V1A758-1" ], "evidence": [ { "id": "41968", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41968" } ] }, { "id": "47884", "name": "", "equation": "N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "47884", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47884" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZY98", "gene_name": "ST6GALNAC3", "activity": [ { "ec_number": "2.4.3.7", "activity": "an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V0ZY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY98" } ] }, { "ec_number": "2.4.3.7", "activity": "", "evidence": [ { "id": "A0A8V0ZY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY98" } ] } ] }, { "uniprot_ac": "A0A8V1A758", "gene_name": "ST6GALNAC4", "activity": [ { "ec_number": "2.4.3.7", "activity": "an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V1A758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A758" } ] }, { "ec_number": "2.4.3.7", "activity": "", "evidence": [ { "id": "A0A8V1A758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A758" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6VMN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6VMN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6VMN5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 174, "end_pos": 176 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJA4-1", "uniprot_ac": "R4GJA4", "uniprot_id": "R4GJA4_CHICK", "mass": { "chemical_mass": 26943.0, "monoisotopic_mass": 26943.0 }, "refseq": { "ac": "XP_001233834", "name": "ras-related and estrogen-regulated growth inhibitor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233834" }, "gene_names": [ { "name": "LOC770492", "type": "recommended", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ] }, { "name": "LOC770492", "type": "synonym", "evidence": [ { "id": "XP_001233834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233834" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4/entry#names_and_taxonomy" } ] }, { "name": "ras-related and estrogen-regulated growth inhibitor", "type": "synonym", "evidence": [ { "id": "XP_001233834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233834" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233834" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJA4", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC770492", "url": "https://www.uniprot.org/uniprotkb/R4GJA4", "locus": {} } ], "crossref": [ { "id": "R4GJA4", "url": "https://alphafold.ebi.ac.uk/entry/R4GJA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027778", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027778", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770492", "url": "https://www.ncbi.nlm.nih.gov/gene/770492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770492", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770492", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEETAGV", "url": "https://omabrowser.org/oma/group/WEETAGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZXH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJA4", "url": "https://www.orthodb.org/?gene=R4GJA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZRY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJA4", "url": "https://www.uniprot.org/uniprotkb/R4GJA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJA4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFPRPLRRSVSLSPARTLRLVVLGQGAVGKTALTVRFITRRFIGDYDPTLEMIYRHMAVIDGEMVHFEILDTAGQEEDSLQIEEKIKWGDGFAVVYSVTDRCSFDEVMRLCFLINHIHSSPKRSGGSEQPPVVIVANKKDLQFDRMVSTQDGENLSKALKLPFYEISTRDSYEETVAVFNTLYQELMRQGHFSPGSFKRRTVSKVMEKIPKMQASSTLNSAGRSLSFNSFRDYIPE", "length": 237, "header": "tr|R4GJA4-1|R4GJA4_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=LOC770492 PE=3 SV=1 CANONICAL=R4GJA4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRY4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJA4/entry#A0A8V0ZRY4-1", "sequence": { "sequence": "MARALLSLQWDVMATAAWMPNLQHQALTVRFITRRFIGDYDPTLEMIYRHMAVIDGEMVHFEILDTAGQEEDSLQIEEKIKWGDGFAVVYSVTDRCSFDEVMRLCFLINHIHSSPKRSGGSEQPPVVIVANKKDLQFDRMVSTQDGENLSKALKLPFYEISTRDSYEETVAVFNTLYQELMRQGHFSPGSFKRRTVSKVMEKIPKMQASSTLNSAGRSLSFNSFRDYIPE", "length": 230, "header": "tr|A0A8V0ZRY4-1|R4GJA4_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=LOC770492 PE=3 SV=1 CANONICAL=R4GJA4-1" }, "locus": { "chromosome": "5", "start_pos": 1612530, "end_pos": 1602759, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055456.1", "url": "https://www.ensembl.org/id/ENSGALT00010055456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033583.1", "url": "https://www.ensembl.org/id/ENSGALP00010033583.1" } ] } }, { "isoform_ac": "A0A8V0ZXH9-1", "url": "https://www.uniprot.org/uniprotkb/R4GJA4/entry#A0A8V0ZXH9-1", "sequence": { "sequence": "MPHSGFALTVRFITRRFIGDYDPTLEMIYRHMAVIDGEMVHFEILDTAGQEEDSLQIEEKIKWGDGFAVVYSVTDRCSFDEVMRLCFLINHIHSSPKRSGGSEQPPVVIVANKKDLQFDRMVSTQDGENLSKALKLPFYEISTRDSYEETVAVFNTLYQELMRQGHFSPGSFKRRTVSKVMEKIPKMQASSTLNSAGRSLSFNSFRDYIPE", "length": 211, "header": "tr|A0A8V0ZXH9-1|R4GJA4_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=LOC770492 PE=3 SV=1 CANONICAL=R4GJA4-1" }, "locus": { "chromosome": "5", "start_pos": 1606565, "end_pos": 1602759, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"ENSGALP00010033582.1", "url": "https://www.ensembl.org/id/ENSGALP00010033582.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770492", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770492", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "R4GJA4", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "R4GJA4", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", 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"activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": 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"MLYLVGLGLGDAKDITVKGLEVVRRCRRVYLEAYTSVLTVGKEALEEFYGKELILADRETVEQEADSILKDADVCDVAFLVVGDPFGATTHSDLVLRAVQLGIPYQVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWKPESFFDKIKRNRQNGMHTLCLLVNE", "length": 166, "header": "tr|A0A8V1A1A9-1|F1P418_CHICK Computationally mapped isoform of diphthine methyl ester synthase OS=Gallus gallus OX=9031 GN=DPH5 PE=1 SV=1 CANONICAL=F1P418-1" }, "locus": { "chromosome": "8", "start_pos": 11468855, "end_pos": 11453494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057585.1", "url": "https://www.ensembl.org/id/ENSGALT00010057585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034978.1", "url": "https://www.ensembl.org/id/ENSGALP00010034978.1" } ] } }, { "isoform_ac": "F1P418-1", "url": "https://www.uniprot.org/uniprotkb/F1P418/entry#F1P418-1", "sequence": { "sequence": "MLYLVGLGLGDAKDITVKGLEVVRRCRRVYLEAYTSVLTVGKEALEEFYGKELILADRETVEQEADSILKDADVCDVAFLVVGDPFGATTHSDLVLRAVQLGIPYQVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWKPESFFDKIKRNRQNGMHTLCLLDIKVKEQSLDNLMKGRKIYEPSRYMSVNQAAEQLLDIIRNRRLQGEEPEITENTICVGLARVGAPDQKIASGTLYQMSTVELGGPLHSMIVTGTMHPLELEMLKLFSVDSSNFENNAFQKTT", "length": 285, "header": "tr|F1P418-1|F1P418_CHICK Isoform 1 of diphthine methyl ester synthase OS=Gallus gallus OX=9031 GN=DPH5 PE=1 SV=2 CANONICAL=F1P418-1" }, "locus": { "chromosome": "8", "start_pos": 11470834, "end_pos": 11453494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057591.1", "url": "https://www.ensembl.org/id/ENSGALT00010057591.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034981.1", "url": "https://www.ensembl.org/id/ENSGALP00010034981.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5358493", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358493", "resource": "Reactome", "description": "Synthesis of diphthamide-EEF2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IU56-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "dph5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLYLVGLGLGDAKDITVKGLEIIRKCSRVYLEAYTSILTVGKDALEEYYGRELLLADRDMVEQEADEILKGADVCDVAFLVVGDPFGATTHSDLVLRALNAGIQYRVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWRPESFYDKIKKNRDMGLHTLCLLDIKVKEQSMENLMRGRKIYEPPRYMTVAQAAEQLLEILQNRRDRGEELAMTEDTVCVGLARVGAEDQTIRSGTLRELASCDLEGPLHSLIISGHLHPLEVDMLKLFSSPEGLKSLKMTDSSTYVS", "length": 288 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S569-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLYMIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSILTVGKEVLEEFYGRKLILADREEVEQEADNILKDADIGDVAFLVVGDPFGATTHSDLILRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRLNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRMRGEEPAVTEETLCVGLARVGAEDQKIAAGTLQQMCTVDLGGPLHSLIITGGSLHPLEMEMLRLFSIPEDSSESQSTDAL", "length": 285 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O81769-1", "protein_name": "Probable diphthine methyl ester synthase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLYIIGLGLGDEKDITLRGLEAVKKSQKVYMEAYTSLLSFGLSADGLSNLEKFYGKPIILADREMVEEKAGDMIDEAIDNDVAFLVVGDPFGATTHSDLVVRAKTLGVKVEVVHNASVMNAVGICGLQLYHYGETVSIPFFTETWRPDSFYEKIKKNRSLGLHTLCLLDIRVKEPTFESLCRGGKKQYEPPRYMSVNTAIEQLLEVEQKHGDSVYGEDTQCVGFARLGSEDQTIVAGTMKQLESVDFGAPLHCLVIVGETHPVEEEMLEFYKYKSGN", "length": 277 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P32469-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLYLIGLGLSYKSDITVRGLEAIKKCSRVYLEHYTSILMAASQEELESYYGKEIILADRELVETGSKQILNNADKEDVAFLVVGDPFGATTHTDLVLRAKREAIPVEIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENRKIGLHTLVLLDIKVKEQSIENMARGRLIYEPPRYMSIAQCCEQLLEIEEKRGTKAYTPDTPAVAISRLGSSSQSFKSGTISELANYDSGEPLHSLVILGRQCHELELEYLLEFADDKEKFGKDVANDQEYFKPAAWVPPTEDDSDE", "length": 300 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5E982-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLYMIGLGLGDAKDITVKGLEVVRRCSRVYLETYTSVLTVGKEVLEEFYERKLILADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLILRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGAEDQKIAAGTLQQMSTVDLGGPLHSLIITGGSLHPLEMEMLSLFTIPENSSEAQSIGGL", "length": 285 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q75JG8-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "dph5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLYIIGLGLGDEKDVTIKGFEAIKKSSKIYLEAYTSLLGGSTSIEALEKFYEKKIIIADREMVESGCEEMLKESTENDVSFLVVGDPFGATTHTDLVIRAKELSIPVKVIHNASIMNAIGCCGLQLYSYGQTISMVFFTETTKPDSWYDRVKINRVNGMHTLCLLDIKVKEQSIENMCRGRLIYEPPRFMTVNQCIEQLLEIEEIRKEKVYDQDTLCIGLSRVGQDDQQIISGTMKELLDVDFGAPLHSFIICGDMHFIEKEYFETFRVKKN", "length": 273 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IN02-1", "protein_name": "diphthine methyl ester synthase", "gene_name": "Dph5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFYLIGLGLGDLKDITVKGLEIVKQCSRVYLEMYTSILGCSLEDMQEFYGRPLLLADRDLVEQGADEILAGAGESDVALLVVGDPFGATTHTDFILRAKEKNIPYKVIHNASIMNAVGCCGLQLYKFGETVSIPYWDETWKPDSFYDKIKLNRLHNMHTLCLLDIKVKEPTPESLMRKRKEYMPPRFMTVAEAAHQLLSIVEKKDSLEKNTVLNEQSLCVGLARVGQESQQIAVGTLLEMRSTDLGGPLHSLIIPAKEMHPLEVEFLQQYAPSIKLDDYNH", "length": 281 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9CWQ0-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "Dph5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLILADREEVEQEADNIFKDADVSDVAFLVVGDPFGATTHSDLILRATKLGIPYQVIHNASIMNAVGCCGLQLYRFGETVSIVFWTDTWRPESFFDKVKRNRANGMHTLCLLDIKVKEQSLENLIRGRKIYEPPRYMSVNQAAQQLLEIVQNHRARGEEPAITEETLCVGLARVGAEDQKIAAGTLQQMCTVSLGEPLHSLVITGGNLHPLEMEMLSLFSIPESQSTDGL", "length": 281 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2P9-1", "protein_name": "Diphthine methyl ester synthase", "gene_name": "DPH5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL", "length": 285 }, "evidence": [ { "id": "F1P418", "url": "https://omabrowser.org/oma/group/F1P418/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "diphthine synthase activity", "id": "GO:0004164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004164", "evidence": [ { "database": "UniProtKB", "id": "F1P418", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ], "pmid": "" }, { "name": "diphthine methyl ester synthase activity", "id": "GO:0141133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141133", "evidence": [ { "database": "UniProtKB", "id": "F1P418", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1P418", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ], "pmid": "" }, { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "F1P418", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P418", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "42652", "name": "", "equation": "2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P418-1" ], "evidence": [ { "id": "42652", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42652" } ] }, { "id": "R-GGA-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-5358478" ], "output_participant_list": [ "R-GGA-5367025" ], "enzyme_list": [ "F1P418-1" ], "evidence": [ { "id": "R-GGA-5358484", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358484" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-5358478", "participant_name": "EEF2 [cytosol]", "crossref": [ { "id": "A0A8V1A5F0", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010027732", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041134", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010067230", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-5367025", "participant_name": "EEF2 [cytosol]", "crossref": [ { "id": "ENSGALG00010027732", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010067230", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010041134", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A5F0", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1P418", "gene_name": "DPH5", "activity": [ { "ec_number": "2.1.1.314", "activity": "2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "F1P418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ] }, { "ec_number": "2.1.1.314", "activity": "", "evidence": [ { "id": "F1P418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P418" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P418-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 285, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P418-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P418" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P418" }, { "id": "PF00590", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00590" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrapyrrole methylase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 239, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.314", "ec_name": "2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "2.1.1.314", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.314" }, { "id": "2.1.1.314", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.314" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJY1-1", "uniprot_ac": "R4GJY1", "uniprot_id": "R4GJY1_CHICK", "mass": { "chemical_mass": 17665.0, "monoisotopic_mass": 17665.0 }, "refseq": { "ac": "XP_015155034", "name": "ORM1-like protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155034" }, "gene_names": [ { "name": "ORMDL3", "type": "recommended", "evidence": [ { "id": "R4GJY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ] }, { "name": "ORMDL3", "type": "synonym", "evidence": [ { "id": "XP_015155034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155034" } ] } ], "protein_names": [ { "name": "ORM1-like protein", "type": "recommended", "evidence": [ { "id": "R4GJY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJY1/entry#names_and_taxonomy" } ] }, { "name": "ORM1-like protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015155034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155034" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155034" } ] }, { "annotation": "Plays an essential role in the homeostatic regulation of sphingolipid de novo biosynthesis by modulating the activity of the serine palmitoyltransferase (SPT) in response to ceramide levels. When complexed to SPT, the binding of ceramides to its N-terminus stabilizes a conformation that block SPT substrate entry, hence preventing SPT catalytic activity. Through this mechanism, maintains ceramide levels at sufficient concentrations for the production of complex sphingolipids, but which prevents the accumulation of ceramides to levels that trigger apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZYN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYN0#function" }, { "database": "UniProtKB", "id": "ARBA00045896", "url": "https://www.uniprot.org/uniprotkb/ARBA00045896#function" }, { "database": "UniProtKB", "id": "A0A8V1A652", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A652#function" }, { "database": "UniProtKB", "id": "A0A8V1A656", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A656#function" }, { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ORMDL3", "url": "https://www.uniprot.org/uniprotkb/R4GJY1", "locus": {} } ], "crossref": [ { "id": "R4GJY1", "url": "https://alphafold.ebi.ac.uk/entry/R4GJY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029142", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426131", "url": "https://www.ncbi.nlm.nih.gov/gene/426131", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426131", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426131", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTAYILI", "url": "https://omabrowser.org/oma/group/WTAYILI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYN0", "url": "https://www.orthodb.org/?gene=A0A8V0ZYN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A652", "url": "https://www.orthodb.org/?gene=A0A8V1A652", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A656", "url": "https://www.orthodb.org/?gene=A0A8V1A656", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJY1", "url": "https://www.orthodb.org/?gene=R4GJY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12665", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12665", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A652", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A652", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A652-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A652-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A656", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A656", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A656-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A656-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJY1-1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYILGIGLLHVVLLSIPFFSVPVVWTLTNIIHNMSMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTIMPIVLYFLTSFYTKYDRIHFVINTISLMSVLIPKLPQFHGVRIFGINKY", "length": 153, "header": "tr|R4GJY1-1|R4GJY1_CHICK Isoform 1 of ORM1-like protein OS=Gallus gallus OX=9031 GN=ORMDL3 PE=3 SV=2 CANONICAL=R4GJY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYN0-1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1/entry#A0A8V0ZYN0-1", "sequence": { "sequence": "LAEKGLKYPFARETGIAAALLPEIGISAPPRLRPSDRNLLRAGNAQIDRDKHPLPSPPLRPSDKAPCGSRRAEGQHSNRGDAFVGWRNAAGGGDAPPGAKRESMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTIMPIVLYFLTSFYTKYDRIHFVINTISLMSVLIPKLPQFHGVRIFGINKY", "length": 197, "header": "tr|A0A8V0ZYN0-1|R4GJY1_CHICK Computationally mapped isoform of ORM1-like protein OS=Gallus gallus OX=9031 GN=ORMDL3 PE=3 SV=1 CANONICAL=R4GJY1-1" }, "locus": { "chromosome": "27", "start_pos": 4292357, "end_pos": 4288566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060059.1", "url": "https://www.ensembl.org/id/ENSGALT00010060059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036819.1", "url": "https://www.ensembl.org/id/ENSGALP00010036819.1" } ] } }, { "isoform_ac": "A0A8V1A652-1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1/entry#A0A8V1A652-1", "sequence": { "sequence": "MRSLGGGTQRAVGTLLRERSGRGGKTRATMNVGTAHSEVNPNTRVMNSRGIWLSYILGIGLLHVVLLSIPFFSVPVVWTLTNIIHNMSMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTIMPIVLYFLTSFYTKYDRIHFVINTISLMSVLIPKLPQFHGVRIFGINKY", "length": 182, "header": "tr|A0A8V1A652-1|R4GJY1_CHICK Computationally mapped isoform of ORM1-like protein OS=Gallus gallus OX=9031 GN=ORMDL3 PE=3 SV=1 CANONICAL=R4GJY1-1" }, "locus": { "chromosome": "27", "start_pos": 4292357, "end_pos": 4288807, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060058.1", "url": "https://www.ensembl.org/id/ENSGALT00010060058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036818.1", "url": "https://www.ensembl.org/id/ENSGALP00010036818.1" } ] } }, { "isoform_ac": "A0A8V1A656-1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1/entry#A0A8V1A656-1", "sequence": { "sequence": "MAVSPRCPRRTPLPRNATTTSHRPQPRSHHSADGGRLLRVPLLAGQRFEKSVSAITCRKALPTCSSCDAEPQTMPVEEPAARSTARISSCSRQSHSQGLLERFTLAFTLLRTSLLSDTSLLEDRSRERRWSASPRNAPLSTAAMALWDRSSSSSSGRSRKASRGRKGMRLESRGGKTRATMNVGTAHSEVNPNTRVMNSRGIWLSYILGIGLLHVVLLSIPFFSVPVVWTLTNIIHNMSMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTIMPIVLYFLTSFYTKYDRIHFVINTISLMSVLIPKLPQFHGVRIFGINKY", "length": 333, "header": "tr|A0A8V1A656-1|R4GJY1_CHICK Computationally mapped isoform of ORM1-like protein OS=Gallus gallus OX=9031 GN=ORMDL3 PE=3 SV=1 CANONICAL=R4GJY1-1" }, "locus": { "chromosome": "27", "start_pos": 4292357, "end_pos": 4282384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060063.1", "url": "https://www.ensembl.org/id/ENSGALT00010060063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036823.1", "url": "https://www.ensembl.org/id/ENSGALP00010036823.1" } ] } }, { "isoform_ac": "R4GJY1-1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1/entry#R4GJY1-1", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYILGIGLLHVVLLSIPFFSVPVVWTLTNIIHNMSMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTIMPIVLYFLTSFYTKYDRIHFVINTISLMSVLIPKLPQFHGVRIFGINKY", "length": 153, "header": "tr|R4GJY1-1|R4GJY1_CHICK Isoform 1 of ORM1-like protein OS=Gallus gallus OX=9031 GN=ORMDL3 PE=3 SV=2 CANONICAL=R4GJY1-1" }, "locus": { "chromosome": "27", "start_pos": 4292357, "end_pos": 4291073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060061.1", "url": "https://www.ensembl.org/id/ENSGALT00010060061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036821.1", "url": "https://www.ensembl.org/id/ENSGALP00010036821.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426131", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426131", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F4K005-1", "protein_name": "ORMDL family protein", "gene_name": "ATORM2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYVRALPTTDVNRNTEWFTYPGVWTTYILILFFSWLLVLSVFHCSPGIAWTIVHLAHFTVTYHSFHWKKGTPFGDDQGVYNRLTWWEQIDNGKQLTRNRKFLTVVPVVL", "length": 109 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3INW0-1", "protein_name": "ORM1-like protein", "gene_name": "Ormdl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMSVLIPKLPQLHGVRIFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q06144-1", "protein_name": "Protein ORM2", "gene_name": "ORM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MIDRTKNESPAFEESPLTPNVSNLKPFPSQSNKISTPVTDHRRRRSSSVISHVEQETFEDENDQQMLPNMNATWVDQRGAWLIHIVVIVLLRLFYSLFGSTPKWTWTLTNMTYIIGFYIMFHLVKGTPFDFNGGAYDNLTMWEQINDETLYTPTRKFLLIVPIVLFLISNQYYRNDMTLFLSNLAVTVLIGVVPKLGITHRLRISIPGITGRAQIS", "length": 216 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0VD15-1", "protein_name": "ORM1-like protein 3", "gene_name": "ORMDL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFILNTVSLMSVLIPKLPQLHGVRIFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XJR6-1", "protein_name": "ORM1-like protein 3", "gene_name": "ormdl3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLGIGLLHIILLSIPFVSVPVVWTLTNLIHNMCMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIILYFLTSFYTKYDRVHFVINTISLLTVLIPKLPQFHGVRLFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6QI25-1", "protein_name": "ORM1-like protein 3", "gene_name": "Ormdl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMSVLIPKLPQLHGVRIFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N138-1", "protein_name": "ORM1-like protein 3", "gene_name": "ORMDL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSVLIPKLPQLHGVRIFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CPZ6-1", "protein_name": "ORM1-like protein 3", "gene_name": "Ormdl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMTVLIPKLPQLHGVRIFGINKY", "length": 153 }, "evidence": [ { "id": "R4GJY1", "url": "https://omabrowser.org/oma/group/R4GJY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of ceramide biosynthetic process", "id": "GO:2000303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000303", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" }, { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" }, { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" }, { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" }, { "name": "intracellular sphingolipid homeostasis", "id": "GO:0090156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090156", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" }, { "name": "serine palmitoyltransferase complex", "id": "GO:0017059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017059", "evidence": [ { "database": "UniProtKB", "id": "R4GJY1", "url": "https://www.uniprot.org/uniprotkb/R4GJY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6RIR9-1", "uniprot_ac": "F6RIR9", "uniprot_id": "F6RIR9_CHICK", "mass": { "chemical_mass": 27957.0, "monoisotopic_mass": 27957.0 }, "refseq": { "ac": "NP_001257645", "name": "derlin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257645" }, "gene_names": [ { "name": "DERL3", "type": "recommended", "evidence": [ { "id": "F6RIR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ] }, { "name": "DERL3", "type": "synonym", "evidence": [ { "id": "NP_001257645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257645" } ] } ], "protein_names": [ { "name": "Derlin", "type": "recommended", "evidence": [ { "id": "F6RIR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RIR9/entry#names_and_taxonomy" } ] }, { "name": "Der1-like domain family, member 3", "type": "synonym", "evidence": [ { "id": "NP_001257645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257645" } ] }, { "name": "derlin-3", "type": "synonym", "evidence": [ { "id": "NP_001257645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257645" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU296761.1, CD218761.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU296761.1, AJ721085.1 and BU262556.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001257645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257645" } ] }, { "annotation": "Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZZW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZW4#function" }, { "database": "UniProtKB", "id": "RU363059", "url": "https://www.uniprot.org/uniprotkb/RU363059#function" }, { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DERL3", "url": "https://www.uniprot.org/uniprotkb/F6RIR9", "locus": { "chromosome": "15", "start_pos": 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Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZZW4", "url": "https://www.orthodb.org/?gene=A0A8V0ZZW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RIR9", "url": "https://www.orthodb.org/?gene=F6RIR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001257645", "url": 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GN=DERL3 PE=3 SV=1 CANONICAL=F6RIR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZW4-1", "url": "https://www.uniprot.org/uniprotkb/F6RIR9/entry#A0A8V0ZZW4-1", "sequence": { "sequence": "MAYQGLAQEYLGMPAVTRAYTTACVLTTAAVIWRLITNFLFFGPLGFSFFFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFASLFFLGQAFTIMLVYVWSRRNPYIRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIIDLLGIAVGHIYYFLEDVFPNQPGGKKLLLTPSFLKMVFDTPEEDPNYNPLPEDHPANQPGDQDQQQQRPL", "length": 219, "header": "tr|A0A8V0ZZW4-1|F6RIR9_CHICK Computationally mapped isoform of Derlin OS=Gallus gallus OX=9031 GN=DERL3 PE=3 SV=1 CANONICAL=F6RIR9-1" }, "locus": { "chromosome": "15", "start_pos": 8019044, "end_pos": 8015138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063430.1", "url": "https://www.ensembl.org/id/ENSGALT00010063430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039154.1", "url": "https://www.ensembl.org/id/ENSGALP00010039154.1" } ] } }, { "isoform_ac": "F6RIR9-1", "url": "https://www.uniprot.org/uniprotkb/F6RIR9/entry#F6RIR9-1", "sequence": { "sequence": "MAYQGLAQEYLGMPAVTRAYTTACVLTTAAVQLEFITPFQLYFNPDLIFRKLQIWRLITNFLFFGPLGFSFFFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFASLFFLGQAFTIMLVYVWSRRNPYIRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIIDLLGIAVGHIYYFLEDVFPNQPGGKKLLLTPSFLKMVFDTPEEDPNYNPLPEDHPANQPGDQDQQQQRPL", "length": 241, "header": "tr|F6RIR9-1|F6RIR9_CHICK Isoform 1 of Derlin OS=Gallus gallus OX=9031 GN=DERL3 PE=3 SV=1 CANONICAL=F6RIR9-1" }, "locus": { "chromosome": "15", "start_pos": 8019044, "end_pos": 8015138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063428.1", "url": "https://www.ensembl.org/id/ENSGALT00010063428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039153.1", "url": "https://www.ensembl.org/id/ENSGALP00010039153.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416934", "resource": "KEGG Pathway" }, { "id": "R-GGA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-GGA-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" }, { "name": "negative regulation of retrograde protein transport, ER to cytosol", "id": "GO:1904153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904153", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "F6RIR9", "url": "https://www.uniprot.org/uniprotkb/F6RIR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RIR9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 241, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RIR9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RIR9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4E5-1", "uniprot_ac": "F1P4E5", "uniprot_id": "F1P4E5_CHICK", "mass": { "chemical_mass": 36826.0, "monoisotopic_mass": 36826.0 }, "refseq": { "ac": "XP_422548", "name": "geranylgeranyl transferase type-2 subunit beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422548" }, "gene_names": [ { "name": "RABGGTB", "type": "recommended", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ] }, { "name": "RABGGTB", "type": "synonym", "evidence": [ { "id": "XP_422548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422548" } ] } ], "protein_names": [ { "name": "Geranylgeranyl transferase type-2 subunit beta", "type": "recommended", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.60", "type": "synonym", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5/entry#names_and_taxonomy" } ] }, { "name": "geranylgeranyl transferase type-2 subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422548" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_422548.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422548" } ] }, { "annotation": "Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A346", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A346#function" }, { "database": "UniProtKB", "id": "RU365076", "url": "https://www.uniprot.org/uniprotkb/RU365076#function" }, { "database": "UniProtKB", "id": "ARBA00094457", "url": "https://www.uniprot.org/uniprotkb/ARBA00094457#function" }, { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RABGGTB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5", "locus": { "chromosome": "8", "start_pos": 29486763, "end_pos": 29471957, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024073", "url": "https://www.ensembl.org/id/ENSGALG00010024073" } ] } } ], "crossref": [ { "id": "F1P4E5", "url": "https://alphafold.ebi.ac.uk/entry/F1P4E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011388", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02894", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02894", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424723", "url": "https://www.ncbi.nlm.nih.gov/gene/424723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424723", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKRCQCP", "url": "https://omabrowser.org/oma/group/VKRCQCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A346", "url": "https://www.orthodb.org/?gene=A0A8V1A346", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4E5", "url": "https://www.orthodb.org/?gene=F1P4E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8873719", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8873719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21240", "url": "https://www.rhea-db.org/rhea/21240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A346", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A346", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A346-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A346-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4E5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPQKDVVIKPDAPSTLLSEKHADYIASYGTKKDDYEYCMSEYLRMSGVYWGLTAMDLMGQLHRMNKEEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILILYESLHVVDVNKIVEYVQSLQKEDGSFAGDKWGEIDTRFSFCAAATLALLGKLDAIDVGKAVEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITDQLHQINVDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKMIGRLHWIDREKLRCFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKAVNPVFCMPEDVLQRINVQPELVS", "length": 331, "header": "tr|F1P4E5-1|F1P4E5_CHICK Isoform 1 of Geranylgeranyl transferase type-2 subunit beta OS=Gallus gallus OX=9031 GN=RABGGTB PE=1 SV=3 CANONICAL=F1P4E5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQH0-1", "url": "https://www.uniprot.org/uniprotkb/F1P4E5/entry#A0A8V0ZQH0-1", "sequence": { "sequence": "MGTPQKDVVIKPDAPSTLLSEKHADYIASYGTKKDDYEYCMSEYLRMSGVYWGLTAMDLMGQLHRMNKEEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQNVNVKVKKPDYAFERRAGSWKATKHGTVQQELFLFSFETSLVSSRCALMSQI", "length": 155, "header": "tr|A0A8V0ZQH0-1|A0A8V0ZQH0_CHICK Computationally mapped isoform of Geranylgeranyl transferase type II subunit beta OS=Gallus gallus OX=9031 GN=RABGGTB PE=1 SV=1 CANONICAL=F1P4E5-1" }, "locus": { "chromosome": "8", "start_pos": 29478794, "end_pos": 29475133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058677.1", "url": "https://www.ensembl.org/id/ENSGALT00010058677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035674.1", "url": "https://www.ensembl.org/id/ENSGALP00010035674.1" } ] } }, { "isoform_ac": "A0A8V1A346-1", "url": "https://www.uniprot.org/uniprotkb/F1P4E5/entry#A0A8V1A346-1", "sequence": { "sequence": "MEQRKTIITGLWQFCHLLEYCMSEYLRMSGVYWGLTAMDLMGQLHRMNKEEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILILYESLHVVDVNKIVEYVQSLQKEDGSFAGDKWGEIDTRFSFCAAATLALLGKLDAIDVGKAVEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITDQLHQINVDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKMIGRLHWIDREKLRCFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKAVNPVFCMPEDVLQRINVQPELVS", "length": 312, "header": "tr|A0A8V1A346-1|F1P4E5_CHICK Computationally mapped isoform of Geranylgeranyl transferase type-2 subunit beta OS=Gallus gallus OX=9031 GN=RABGGTB PE=1 SV=1 CANONICAL=F1P4E5-1" }, "locus": { "chromosome": "8", "start_pos": 29484702, "end_pos": 29475825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058678.1", "url": "https://www.ensembl.org/id/ENSGALT00010058678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035675.1", "url": "https://www.ensembl.org/id/ENSGALP00010035675.1" } ] } }, { "isoform_ac": "F1P4E5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4E5/entry#F1P4E5-1", "sequence": { "sequence": "MGTPQKDVVIKPDAPSTLLSEKHADYIASYGTKKDDYEYCMSEYLRMSGVYWGLTAMDLMGQLHRMNKEEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILILYESLHVVDVNKIVEYVQSLQKEDGSFAGDKWGEIDTRFSFCAAATLALLGKLDAIDVGKAVEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITDQLHQINVDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKMIGRLHWIDREKLRCFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKAVNPVFCMPEDVLQRINVQPELVS", "length": 331, "header": "tr|F1P4E5-1|F1P4E5_CHICK Isoform 1 of Geranylgeranyl transferase type-2 subunit beta OS=Gallus gallus OX=9031 GN=RABGGTB PE=1 SV=3 CANONICAL=F1P4E5-1" }, "locus": { "chromosome": "8", "start_pos": 29484702, "end_pos": 29475133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058679.1", "url": "https://www.ensembl.org/id/ENSGALT00010058679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035676.1", "url": "https://www.ensembl.org/id/ENSGALP00010035676.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424723", "resource": "KEGG Pathway" }, { "id": "R-GGA-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" } ], "orthologs": [ { "uniprot_canonical_ac": "B0G172-1", "protein_name": "Probable geranylgeranyl transferase type-2 subunit beta", "gene_name": "rabggtb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDNINKESTTTTTTIDHTTNLLIDKHVEYIVKLGSKKDSFEYWVTEHIRMNGMYWGLSSLYLLKSLDKLDKNEVIQWLLSCQKSNGGFGGNTSHDDHLLSTLSAVQILIQYDALDKIDINSVVDYVVKLQREDGSFVGDQWGEVDTRFSYAAIMCLSLLKSLDKINCEKAVEYILSCQNFDGGFGSIPGAESHAGQIFTCVGALSILNEINKIDIDKLGWWLSERQLPNGGLNGRPEKSSDVCYSWWVLSALSAIDRLHWIDNDKLKSYILKCQDNETGGIADKPGDIPDVFHTFFGICGLSLMGYFKDQIESIDPVYALGTKTLQKLGLNLPWNKNL", "length": 339 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "I3L5Z8-1", "protein_name": "MutS protein homolog 4", "gene_name": "MSH4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRPESSPASLPVPGDSSLSVEVRPQVPRCSLGLQETPQSGPSAQAASVSSRPDTSGAAGDRSSSSSCPRAPSALPAQGSYCKSKRSYAENTFASDFTLGTSSSSARGSTCPQIVKTPLSAGNHQRSGYKSWTPQMEYSATSSSAVSAHSPSVVVAVVEGRGLARGEIGMASIDLKSPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCTAEFSTVLMEVQSYYCLAAVAALLKYIEFIQNSLYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDSRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVIARFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKITLKNCNTPLLRAYYGSLEDKRFGIILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLAEKYSLPLRTSFSSARGFFIQMTTDCTALFNDKLPSEFIKISKVKNSYSFTSTDLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISVEKPVANNTYITEGSNFVIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAEQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDVLYPNVENMYFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEASSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRTYLSNLKRKYEADFPRAEQVSGKTEE", "length": 932 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P20133-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "BET2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGSLTLLKEKHIRYIESLDTKKHNFEYWLTEHLRLNGIYWGLTALCVLDSPETFVKEEVISFVLSCWDDKYGAFAPFPRHDAHLLTTLSAVQILATYDALDVLGKDRKVRLISFIRGNQLEDGSFQGDRFGEVDTRFVYTALSALSILGELTSEVVDPAVDFVLKCYNFDGGFGLCPNAESHAAQAFTCLGALAIANKLDMLSDDQLEEIGWWLCERQLPEGGLNGRPSKLPDVCYSWWVLSSLAIIGRLDWINYEKLTEFILKCQDEKKGGISDRPENEVDVFHTVFGVAGLSLMGYDNLVPIDPIYCMPKSVTSKFKKYPYK", "length": 325 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53611-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS", "length": 331 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9B3-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILTFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDINKVVEYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLRRVNVQPELVS", "length": 331 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q84J75-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta 1", "gene_name": "RGTB1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSTSSSQMVQLVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLGCVSEEEVISWLMTCQHESGGFAGNTGHDPHILYTLSAVQILALFDKINILDIGKVSSYVAKLQNEDGSFSGDMWGEIDTRFSYIAICCLSILKCLDKINVEKAVKYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHVDKDSLGWWLCERQLKAGGLNGRPEKLADVCYSWWVLSSLIMIDRVHWIDKAKLVKFILDCQDLDNGGISDRPEDAVDIFHTYFGVAGLSLLEYPGVKVIDPAYALPVDVVNRIIFTK", "length": 321 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9XZ68-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RabGGTb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFTTFVKPSNGGGDSGGGGDADGGGQKLQFWKHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFVKRCQCPNTGGFAPCEGHDPHLLYTLSAIQILCTYDALEEIDREAVVRFVVGLQQPDGSFFGDKWGEVDTRFSFCAVASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLLDVDKLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGLSLLGHSGLKAINPTLCMPQYIIDRLGIKPQLLPRP", "length": 347 }, "evidence": [ { "id": "F1P4E5", "url": "https://omabrowser.org/oma/group/F1P4E5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "Rab geranylgeranyltransferase activity", "id": "GO:0004663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004663", "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "pmid": "" }, { "name": "protein prenyltransferase activity", "id": "GO:0008318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008318", "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Rab-protein geranylgeranyltransferase complex", "id": "GO:0005968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005968", "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1P4E5", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21240", "name": "", "equation": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4E5-1", "A0A8V0YNE3-1", "F1NE58-1" ], "evidence": [ { "id": "21240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21240" } ] }, { "id": "R-GGA-8870457", "name": "FarC-PTP4A2 binds RABGGTB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4E5-1" ], "evidence": [ { "id": "R-GGA-8870457", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8870457" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YNE3", "gene_name": "FNTA", "activity": [ { "ec_number": "2.5.1.58", "activity": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] }, { "ec_number": "2.5.1.58", "activity": "", "evidence": [ { "id": "A0A8V0YNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE3" } ] } ] }, { "uniprot_ac": "F1NE58", "gene_name": "PGGT1B", "activity": [ { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "F1NE58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE58" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "F1NE58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE58" } ] } ] }, { "uniprot_ac": "F1P4E5", "gene_name": "RABGGTB", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4E5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 331, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4E5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4E5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4E5" }, { "id": "PF00432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenyltransferase alpha-alpha toroid", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 315, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.60", "ec_name": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "2.5.1.60", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60" }, { "id": "2.5.1.60", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.60" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "H9L0S2-1", "uniprot_ac": "H9L0S2", "uniprot_id": "H9L0S2_CHICK", "mass": { "chemical_mass": 25565.0, "monoisotopic_mass": 25565.0 }, "refseq": { "ac": "NP_001264617", "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" }, "gene_names": [ { "name": "NTMT1", "type": "recommended", "evidence": [ { "id": "H9L0S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ] }, { "name": "AD-003", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "C9orf32", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "HOMT1A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "METTL11A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "NRMT", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "NTM1A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "NTMT1", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] } ], "protein_names": [ { "name": "protein N-terminal methyltransferase", "type": "recommended", "evidence": [ { "id": "H9L0S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L0S2/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.244", "type": "synonym", "evidence": [ { "id": "H9L0S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L0S2/entry#names_and_taxonomy" } ] }, { "name": "N-terminal RCC1 methyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "X-Pro-Lys N-terminal protein methyltransferase 1A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "alpha N-terminal protein methyltransferase 1A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "methyltransferase like 11A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] }, { "name": "methyltransferase-like protein 11A", "type": "synonym", "evidence": [ { "id": "NP_001264617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01001139.1, HAEL01000752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001264617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NTMT1", "url": "https://www.uniprot.org/uniprotkb/H9L0S2", "locus": { "chromosome": "17", "start_pos": 6249317, "end_pos": 6244214, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028008", "url": "https://www.ensembl.org/id/ENSGALG00010028008" } ] } } ], "crossref": [ { "id": "H9L0S2", "url": "https://alphafold.ebi.ac.uk/entry/H9L0S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017611", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017611", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425539", "url": "https://www.ncbi.nlm.nih.gov/gene/425539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425539", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVRMYCL", "url": "https://omabrowser.org/oma/group/PVRMYCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6T4", "url": "https://www.orthodb.org/?gene=A0A8V1A6T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "H9L0S2", "url": "https://www.orthodb.org/?gene=H9L0S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12753:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12753:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54712", "url": "https://www.rhea-db.org/rhea/54712", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54724", "url": "https://www.rhea-db.org/rhea/54724", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54736", "url": "https://www.rhea-db.org/rhea/54736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A6T4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L0S2-1", "url": "https://www.uniprot.org/uniprotkb/H9L0S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSEVVENEFEFYSKAEKYWKDVPATVDGMLGGYGHISSIDINSSRKFLQRFLRDGPNRTGTTRALDCGAGIGRITKRLLLPLFKTVDMVDVTEDFLTKAKSYLGEEGRRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDNHLSDFLKRCRAGLRPNGIVVIKDNMAQEGVIMDDVDSSVCRDLDVVRKIIRRAGLHLLAEERQENFPDEIYHVYTFAMR", "length": 223, "header": "tr|H9L0S2-1|H9L0S2_CHICK Isoform 1 of protein N-terminal methyltransferase OS=Gallus gallus OX=9031 GN=NTMT1 PE=1 SV=3 CANONICAL=H9L0S2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6T4-1", "url": "https://www.uniprot.org/uniprotkb/H9L0S2/entry#A0A8V1A6T4-1", "sequence": { "sequence": "MLIAGNNTCSSGQLTSKCESHKGACPAASMTSEVVENEFEFYSKAEKYWKDVPATVDGMLGGYGHISSIDINSSRKFLQRFLRDGPNRTGTTRALDCGAGIGRITKRLLLPLFKTVDMVDVTEDFLTKAKSYLGEEGRRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDNHLSDFLKRCRAGLRPNGIVVIKDNMAQEGVIMDDVDSSVCRDLDVVRKIIRRAGLHLLAEERQENFPDEIYHVYTFAMR", "length": 252, "header": "tr|A0A8V1A6T4-1|H9L0S2_CHICK Computationally mapped isoform of protein N-terminal methyltransferase OS=Gallus gallus OX=9031 GN=NTMT1 PE=1 SV=1 CANONICAL=H9L0S2-1" }, "locus": { "chromosome": "17", "start_pos": 6248179, "end_pos": 6244466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067889.1", "url": "https://www.ensembl.org/id/ENSGALT00010067889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041632.1", "url": "https://www.ensembl.org/id/ENSGALP00010041632.1" } ] } }, { "isoform_ac": "H9L0S2-1", "url": "https://www.uniprot.org/uniprotkb/H9L0S2/entry#H9L0S2-1", "sequence": { "sequence": "MTSEVVENEFEFYSKAEKYWKDVPATVDGMLGGYGHISSIDINSSRKFLQRFLRDGPNRTGTTRALDCGAGIGRITKRLLLPLFKTVDMVDVTEDFLTKAKSYLGEEGRRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDNHLSDFLKRCRAGLRPNGIVVIKDNMAQEGVIMDDVDSSVCRDLDVVRKIIRRAGLHLLAEERQENFPDEIYHVYTFAMR", "length": 223, "header": "tr|H9L0S2-1|H9L0S2_CHICK Isoform 1 of protein N-terminal methyltransferase OS=Gallus gallus OX=9031 GN=NTMT1 PE=1 SV=3 CANONICAL=H9L0S2-1" }, "locus": { "chromosome": "17", "start_pos": 6248179, "end_pos": 6246986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067887.1", "url": "https://www.ensembl.org/id/ENSGALT00010067887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041630.1", "url": "https://www.ensembl.org/id/ENSGALP00010041630.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:425539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425539", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QK51-1", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "NTMT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSEVIEDEKQFYSKAETYWKEVPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCALDCGAGIGITKRLLLPLFGVVDMVDVTEDFLVKAKSYLGEEGKRVRNYFCCGLQDFSPEPHSYDVIWIQWVIGHLTDQHLAEFLRRCKRGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVHRIIRRAGLSLLAQERQENLPDEIYHVYSLALR", "length": 222 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GBX8-1", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "Ntmt1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCLHLPQRSKAVVRDSTASDIMTSEVIEDEKQFYSKAKIYWKQIPPTVDGMLGGYGHISNIDLNSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFRVVDMVDVTEDFLAKAKTYLGEEGKRVRNYFCCGLQDFSPEPNSYDVIWIQWVIGHLTDQHLAEFLRRCKQGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLEVVRRIIRSAGLSLLAEERQENLPDEIYHVYSFALR", "length": 244 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MKD1-1", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "NTMT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSEVIEDEKQFYSKAKTYWKEVPATVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSYALDCGAGIGRITKRLLLPLFGVVDMVDVTEDFLVKAKTYLGEEGKRVRNFFCCGLQDFSPEPQSYDVIWIQWVIGHLTDQHLAEFLRRCKRGLRPNGIIVIKDNMAQEGVILDDVDSSVCRALDVVHRIVRSAGLSLLAQERQENLPDEIYHVYSLALR", "length": 223 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P38340-1", "protein_name": "Alpha N-terminal protein methyltransferase 1", "gene_name": "TAE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDVPADSHIKYEDAIDYWTDVDATVDGVLGGYGEGTVVPTMDVLGSNNFLRKLKSRMLPQENNVKYAVDIGAGIGRVSKTMLHKHAAKIDLVEPVKPFIEQMHVELAELKDKGQIGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLPDAELVAFLKRCIVGLQPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKFRQIFEEAGLKLIASERQRGLPRELYPVRMYALKPMPN", "length": 232 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55DH6-1", "protein_name": "Alpha N-terminal protein methyltransferase 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIKNEEQQQQTNKLKYPKNLLSSGLDGEGNTYINIEDLWKKELEGKDNKMEDKWYKSADEYWKGVEATVDGMLGGLAQVSPIDVVASKVFIQDFIKGTDSRPPINLNLALDCGAGIGRVAKEFLLPIGFKNVDLVEQNKLFLDKAKSDNFKDDNRVENYYAVGLQDFTFEKKYDCIWIQWVIGHLHDLDFIEFLKKCMDSLTPNGIICIKDNCAKKRFIMDKEDNSVSRTEDHLKYLFDQAGCKLLKSMVQPNFPKELFPVLMFALERK", "length": 270 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJX0-1", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "Ntmt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISNIDLNSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFRVVDMVDVTEDFLAKAKTYLGEEGKRVRNYFCCGLQDFSPEPSSYDVIWIQWVIGHLTDQHLAEFLRRCRRGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLEVVRRIIRSAGLSLLAEERQENLPDEIYHVYSFALR", "length": 223 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PP70-1", "protein_name": "Alpha N-terminal protein methyltransferase 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDICGVDSEGKEFNSVQEMWREEIGEGDETKKTQWYRDGVSYWEGVEASVDGVLGGYGHVNDADIIGSEVFLKTLLQERLVNNVGANQHLVALDCGSGIGRITKNLLIRYFNEVDLLEPVAQFLDAARENLASAGSETHKATNFFCVPLQEFTPAAGRYDVIWVQWCIGHLTDNDFVSFFNRAKGYLKPGGFFVVKENLAKNGFVLDKEDHSITRSDPYFKQLFRQCGLHLYRTKDQKGLPQELFAVKMYALTVDTPPKIHRTRSKTRSNRPQIIK", "length": 276 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6NN40-1", "protein_name": "Alpha N-terminal protein methyltransferase 1", "gene_name": "Ntmt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTTLEEQLSDKLQMMDETTDKVQGSSKQKDDSSIAASSDAKTASPSSSDSSTKVAAPESEFYNKAQKYWSEVPATVNGMLGGLGYISAIDIQGSNVFLREIRVPGNRLALDCGAGIGRVTRNLLIPRFSCVDLVEQDPAFADKAREYCTSEDGSRGKVGQIYNVGLQKFTPTQQYDLVWTQWVLGHLTDRDLVSFFRRIKQGLAPGAFLCLKENVSSSKKTVEDRNDSSVTRPLDSYEHFLKEAGFRIVRKVKQQNFPKGLFPVYMIACKPVSKE", "length": 276 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8R2U4-1", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "gene_name": "Ntmt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISNIDLNSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFRVVDMVDVTEDFLAKAKTYLGEEGKRVRNYFCCGLQDFSPEPGSYDVIWIQWVIGHLTDQHLAEFLRRCKRGLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLEVVRRIIRTAGLSLLAEERQENLPDEIYHVYSFALR", "length": 223 }, "evidence": [ { "id": "H9L0S2", "url": "https://omabrowser.org/oma/group/H9L0S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-terminal protein N-methyltransferase activity", "id": "GO:0071885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071885", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" }, { "name": "spindle organization", "id": "GO:0007051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007051", "evidence": [ { "database": "UniProtKB", "id": "H9L0S2", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54712", "name": "", "equation": "N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "H9L0S2-1" ], "evidence": [ { "id": "54712", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54712" } ] }, { "id": "54724", "name": "", "equation": "N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "H9L0S2-1" ], "evidence": [ { "id": "54724", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54724" } ] }, { "id": "54736", "name": "", "equation": "N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "H9L0S2-1" ], "evidence": [ { "id": "54736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54736" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "H9L0S2", "gene_name": "NTMT1", "activity": [ { "ec_number": "2.1.1.244", "activity": "N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "H9L0S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ] }, { "ec_number": "2.1.1.244", "activity": "", "evidence": [ { "id": "H9L0S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L0S2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.244", "ec_name": "N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "2.1.1.244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.244" }, { "id": "2.1.1.244", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.244" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6R8U4-1", "uniprot_ac": "F6R8U4", "uniprot_id": "F6R8U4_CHICK", "mass": { "chemical_mass": 19158.0, "monoisotopic_mass": 19158.0 }, "refseq": { "ac": "XP_015155970", "name": "guided entry of tail-anchored proteins factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970" }, "gene_names": [ { "name": "WRB", "type": "recommended", "evidence": [ { "id": "F6R8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ] }, { "name": "UCP-1", "type": "synonym", "evidence": [ { "id": "XP_015155970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970" } ] }, { "name": "WRB", "type": "synonym", "evidence": [ { "id": "XP_015155970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970" } ] } ], "protein_names": [ { "name": "Guided entry of tail-anchored proteins factor 1", "type": "recommended", "evidence": [ { "id": "F6R8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#names_and_taxonomy" } ] }, { "name": "Tail-anchored protein insertion receptor WRB", "type": "synonym", "evidence": [ { "id": "F6R8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#names_and_taxonomy" } ] }, { "name": "Tryptophan-rich basic protein", "type": "synonym", "evidence": [ { "id": "F6R8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#names_and_taxonomy" } ] }, { "name": "guided entry of tail-anchored proteins factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155970", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WRB", "url": "https://www.uniprot.org/uniprotkb/F6R8U4", "locus": { "chromosome": "1", "start_pos": 108092042, "end_pos": 108085542, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013413", "url": "https://www.ensembl.org/id/ENSGALG00010013413" } ] } } ], "crossref": [ { "id": "F6R8U4", "url": "https://alphafold.ebi.ac.uk/entry/F6R8U4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016070", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770415", "url": "https://www.ncbi.nlm.nih.gov/gene/770415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AEWIISF", "url": "https://omabrowser.org/oma/group/AEWIISF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSB3", "url": "https://www.orthodb.org/?gene=A0A8V0YSB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSC3", "url": "https://www.orthodb.org/?gene=A0A8V0YSC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6R8U4", "url": "https://www.orthodb.org/?gene=F6R8U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42650:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42650:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155970", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8U4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESGAWLLVLSAVFLCNALKILLPSCSSIISKLLQKDAEQESQMRAEIQNMKQELSTISMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVINIVFYILQAALMISLIWKYYSEPVTVLPSKWLAPLERLVAFPTGVAGGVGITCWLVVCNKVVAIMLHPFS", "length": 170, "header": "tr|F6R8U4-1|F6R8U4_CHICK Isoform 1 of Guided entry of tail-anchored proteins factor 1 OS=Gallus gallus OX=9031 GN=WRB PE=1 SV=1 CANONICAL=F6R8U4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YSB3-1", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#A0A8V0YSB3-1", "sequence": { "sequence": "MSVIRRVHNEEISKLLQKDAEQESQMRAEIQNMKQELSTISMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVINIVFYILQAALMISLIWKYYSEPVTVLPSKWLAPLERLVAFPTGVAGGVGITCWLVVCNKVVAIMLHPFS", "length": 151, "header": "tr|A0A8V0YSB3-1|F6R8U4_CHICK Computationally mapped isoform of Guided entry of tail-anchored proteins factor 1 OS=Gallus gallus OX=9031 GN=WRB PE=1 SV=1 CANONICAL=F6R8U4-1" }, "locus": { "chromosome": "1", "start_pos": 108090671, "end_pos": 108086080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032294.1", "url": "https://www.ensembl.org/id/ENSGALT00010032294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019084.1", "url": "https://www.ensembl.org/id/ENSGALP00010019084.1" } ] } }, { "isoform_ac": "A0A8V0YSC3-1", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#A0A8V0YSC3-1", "sequence": { "sequence": "MAESGAWLLVLSAVFLCNALKILLPSCSSIISKLLQKDAEQESQMRAEIQNMKQELSTISMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVINIVFYILQAALMISLIWKYYSEPVTVLPSKWLAPLERLVAFPTGVAAVERILCIQHAYWTLLLCRIREQSLEGGVGITCWLVVCNKVVAIMLHPFS", "length": 196, "header": "tr|A0A8V0YSC3-1|F6R8U4_CHICK Computationally mapped isoform of Guided entry of tail-anchored proteins factor 1 OS=Gallus gallus OX=9031 GN=WRB PE=1 SV=1 CANONICAL=F6R8U4-1" }, "locus": { "chromosome": "1", "start_pos": 108090671, "end_pos": 108085580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032304.1", "url": "https://www.ensembl.org/id/ENSGALT00010032304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019094.1", "url": "https://www.ensembl.org/id/ENSGALP00010019094.1" } ] } }, { "isoform_ac": "F6R8U4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8U4/entry#F6R8U4-1", "sequence": { "sequence": "MAESGAWLLVLSAVFLCNALKILLPSCSSIISKLLQKDAEQESQMRAEIQNMKQELSTISMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVINIVFYILQAALMISLIWKYYSEPVTVLPSKWLAPLERLVAFPTGVAGGVGITCWLVVCNKVVAIMLHPFS", "length": 170, "header": "tr|F6R8U4-1|F6R8U4_CHICK Isoform 1 of Guided entry of tail-anchored proteins factor 1 OS=Gallus gallus OX=9031 GN=WRB PE=1 SV=1 CANONICAL=F6R8U4-1" }, "locus": { "chromosome": "1", "start_pos": 108090671, "end_pos": 108085580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032300.1", "url": "https://www.ensembl.org/id/ENSGALT00010032300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019090.1", "url": "https://www.ensembl.org/id/ENSGALP00010019090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQQ5-1", "protein_name": "Guided entry of tail-anchored proteins factor 1", "gene_name": "GET1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAEADRWAWLLVLSFVFGCNVLRILLPSFSSFMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYILQAALMVSLIWKYYSVPVAVVPRKWITPLDRLVAFPTRVAGGVGITCWILVCNKVVAIVLHPFS", "length": 174 }, "evidence": [ { "id": "F6R8U4", "url": "https://omabrowser.org/oma/group/F6R8U4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00258-1", "protein_name": "Guided entry of tail-anchored proteins factor 1", "gene_name": "GET1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSAAADHWAWLLVLSFVFGCNVLRILLPSFSSFMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGVGITCWILVCNKVVAIVLHPFS", "length": 174 }, "evidence": [ { "id": "F6R8U4", "url": "https://omabrowser.org/oma/group/F6R8U4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZ26-1", "protein_name": "Guided entry of tail-anchored proteins factor 1", "gene_name": "GET1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAAEADRWAWLLVLSFVFGCNVLRILLPSFSFFMSRVLQKDAEQESQMRAEIQGMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYILQAALMVSLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGVGITCWILVCNKVVAIVLHPFS", "length": 174 }, "evidence": [ { "id": "F6R8U4", "url": "https://omabrowser.org/oma/group/F6R8U4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DRM0-1", "protein_name": "Guided entry of tail-anchored proteins factor 1", "gene_name": "get1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAGFNWFLVLSSVFLCNLVKTFLPSISSFLSKIFHKDADQEMEMRTEIQNMKMELSTISMMDEFARYARLERKINKMTDQLKTLVKSRTAQQAKMKWIVNIAFYILQAALMISLILKYYADPVTVVPSKWIAPLERLVAFPSGVAGGVGITCWLVVCNKVVALILQAVS", "length": 170 }, "evidence": [ { "id": "F6R8U4", "url": "https://omabrowser.org/oma/group/F6R8U4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K0D7-1", "protein_name": "Guided entry of tail-anchored proteins factor 1", "gene_name": "Get1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASETDRWAWLLVLSFVFGCNLLRILLPSLSSFISRVLQKDAEQESQMRAEIQGMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWFISVAFYILQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGIGITCWILVCNKVVAIVLHPFS", "length": 174 }, "evidence": [ { "id": "F6R8U4", "url": "https://omabrowser.org/oma/group/F6R8U4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "pmid": "" }, { "name": "GET complex", "id": "GO:0043529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043529", "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "F6R8U4", "url": "https://www.uniprot.org/uniprotkb/F6R8U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R8U4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 170, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R8U4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R8U4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4Q2-1", "uniprot_ac": "F1P4Q2", "uniprot_id": "F1P4Q2_CHICK", "mass": { "chemical_mass": 41980.0, "monoisotopic_mass": 41980.0 }, "refseq": {}, "gene_names": [ { "name": "LOC771085", "type": "recommended", "evidence": [ { "id": "F1P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC771085", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2", "locus": {} } ], "crossref": [ { "id": "F1P4Q2", "url": "https://alphafold.ebi.ac.uk/entry/F1P4Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016802", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016802", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK03", "url": "https://www.orthodb.org/?gene=A0A8V0YK03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT42", "url": "https://www.orthodb.org/?gene=A0A8V0YT42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4Q2", "url": "https://www.orthodb.org/?gene=F1P4Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YK03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4Q2-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHTWTYNLSFGAPTDPVEPRAGLSRNGHTVVAVFLGFILFFGFLNNLIVLILFCKFKTLRNPVNMLLLNISISDMLVCISGTTLSFASNIHGKWIGGEHGCRWYGFVNSCFGIVSLISLAVLSYERYSTLTLCNKRSDDYRKALLAVGGSWVYSLLWTVPPLLGWSSYGIEGAGTSCSVRWSSETAESTSYIICLFIFCLVIPVMVMMYCYGRLLYAVKQVGKIHKNTARKREYHVLFMVITTVICYLVCWIPYGVIALLATFGKPGVVTPVASIIPSILAKSSTVCNPIIYILMNKQFYKCFRQLFHCQPPSSTDGEPTCHSKVTVIQLNQKTDGGKLCNNKPRPETDNKVTSLLHPEPGLEPAAKTVPPISEALVA", "length": 379, "header": "tr|F1P4Q2-1|F1P4Q2_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC771085 PE=3 SV=4 CANONICAL=F1P4Q2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK03-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2/entry#A0A8V0YK03-1", "sequence": { "sequence": "MNHTWTYNLSFGAPTDPVEPRAGLSRNGHTVVAVFLGFILFFGFLNNLIVLILFCKFKTLRNPVNMLLLNISISDMLVCISGTTLSFASNIHGKWIGGEHGCRWYGFVNSCFGIVSLISLAVLSYERYSTLTLCNKRSDDYRKALLAVGGSWVYSLLWTVPPLLGWSSYGIEGAGTSCSVRWSSETAESTSYIICLFIFCLVIPVMVMMYCYGRLLYAVKQVGKIHKNTARKREYHVLFMVITTVICYLVCWIPYGVIALLATFGKPGVVTPVASIIPSILAKSSTVCNPIIYILMNKQECMDAAFFSSTLEN", "length": 313, "header": "tr|A0A8V0YK03-1|F1P4Q2_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC771085 PE=3 SV=1 CANONICAL=F1P4Q2-1" }, "locus": { "chromosome": "1", "start_pos": 135750503, "end_pos": 135695434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036514.1", "url": "https://www.ensembl.org/id/ENSGALT00010036514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021263.1", "url": "https://www.ensembl.org/id/ENSGALP00010021263.1" } ] } }, { "isoform_ac": "A0A8V0YT42-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2/entry#A0A8V0YT42-1", "sequence": { "sequence": "MNHTWTYNLSFGAPTDPVEPRAGLSRNGHTVVAVFLGFILFFGFLNNLIVLILFCKFKTLRNPVNMLLLNISISDMLVCISGTTLSFASNIHGKWIGGEHGCRWYGFVNSCFGIVSLISLAVLSYERYSTLTLCNKRSDDYRKALLAVGGSWVYSLLWTVPPLLGWSSYGIEGAGTSCSVRWSSETAESTSYIICLFIFCLVIPVMVMMYCYGRLLYAVKQFYKCFRQLFHCQPPSSTDGEPTCHSKVTVIQLNQKTDGGKLCNNKPRPETDNKVTSLLHPEPGLEPAAKTVPPM", "length": 295, "header": "tr|A0A8V0YT42-1|F1P4Q2_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC771085 PE=3 SV=1 CANONICAL=F1P4Q2-1" }, "locus": { "chromosome": "1", "start_pos": 135769171, "end_pos": 135695434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036517.1", "url": "https://www.ensembl.org/id/ENSGALT00010036517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021266.1", "url": "https://www.ensembl.org/id/ENSGALP00010021266.1" } ] } }, { "isoform_ac": "F1P4Q2-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2/entry#F1P4Q2-1", "sequence": { "sequence": "MNHTWTYNLSFGAPTDPVEPRAGLSRNGHTVVAVFLGFILFFGFLNNLIVLILFCKFKTLRNPVNMLLLNISISDMLVCISGTTLSFASNIHGKWIGGEHGCRWYGFVNSCFGIVSLISLAVLSYERYSTLTLCNKRSDDYRKALLAVGGSWVYSLLWTVPPLLGWSSYGIEGAGTSCSVRWSSETAESTSYIICLFIFCLVIPVMVMMYCYGRLLYAVKQVGKIHKNTARKREYHVLFMVITTVICYLVCWIPYGVIALLATFGKPGVVTPVASIIPSILAKSSTVCNPIIYILMNKQFYKCFRQLFHCQPPSSTDGEPTCHSKVTVIQLNQKTDGGKLCNNKPRPETDNKVTSLLHPEPGLEPAAKTVPPISEALVA", "length": 379, "header": "tr|F1P4Q2-1|F1P4Q2_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC771085 PE=3 SV=4 CANONICAL=F1P4Q2-1" }, "locus": { "chromosome": "1", "start_pos": 135771301, "end_pos": 135695434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036520.1", "url": "https://www.ensembl.org/id/ENSGALT00010036520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021269.1", "url": "https://www.ensembl.org/id/ENSGALP00010021269.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "photoreceptor activity", "id": "GO:0009881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009881", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "light absorption", "id": "GO:0016037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016037", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q2", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4Q2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 379, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4Q2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 293, "start_aa": "Asn", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GLS1-1", "uniprot_ac": "R4GLS1", "uniprot_id": "R4GLS1_CHICK", "mass": { "chemical_mass": 15247.0, "monoisotopic_mass": 15247.0 }, "refseq": { "ac": "XP_420668", "name": "CDGSH iron-sulfur domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420668" }, "gene_names": [ { "name": "CISD2", "type": "recommended", "evidence": [ { "id": "R4GLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ] }, { "name": "CISD2", "type": "synonym", "evidence": [ { "id": "XP_420668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420668" } ] } ], "protein_names": [ { "name": "CDGSH iron-sulfur domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "R4GLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLS1/entry#names_and_taxonomy" } ] }, { "name": "CDGSH iron-sulfur domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_420668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420668" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420668" } ] }, { "annotation": "Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL6#function" }, { "database": "UniProtKB", "id": "RU369084", "url": "https://www.uniprot.org/uniprotkb/RU369084#function" }, { "database": "UniProtKB", "id": "A0A8V0YYM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM2#function" }, { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CISD2", "url": "https://www.uniprot.org/uniprotkb/R4GLS1", "locus": { "chromosome": "4", "start_pos": 60472702, "end_pos": 60463193, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016900", "url": "https://www.ensembl.org/id/ENSGALG00010016900" } ] } } ], "crossref": [ { "id": "R4GLS1", "url": "https://alphafold.ebi.ac.uk/entry/R4GLS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027860", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027860", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422714", "url": "https://www.ncbi.nlm.nih.gov/gene/422714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422714", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIRKHEP", "url": "https://omabrowser.org/oma/group/QIRKHEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYL6", "url": "https://www.orthodb.org/?gene=A0A8V0YYL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYM2", "url": "https://www.orthodb.org/?gene=A0A8V0YYM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GLS1", "url": "https://www.orthodb.org/?gene=R4GLS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13680:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13680:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10660", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10660", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLS1-1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLESLARIVKVQLPAYLKRLPLPESVGGFLRLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV", "length": 134, "header": "tr|R4GLS1-1|R4GLS1_CHICK Isoform 1 of CDGSH iron-sulfur domain-containing protein 2 OS=Gallus gallus OX=9031 GN=CISD2 PE=1 SV=1 CANONICAL=R4GLS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYL6-1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1/entry#A0A8V0YYL6-1", "sequence": { "sequence": "KIKHQKTGEGLLVLISLSVSYLPKVSKQNLEQIKQGKLQEVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV", "length": 140, "header": "tr|A0A8V0YYL6-1|R4GLS1_CHICK Computationally mapped isoform of CDGSH iron-sulfur domain-containing protein 2 OS=Gallus gallus OX=9031 GN=CISD2 PE=1 SV=1 CANONICAL=R4GLS1-1" }, "locus": { "chromosome": "4", "start_pos": 60469315, "end_pos": 60468140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040779.1", "url": "https://www.ensembl.org/id/ENSGALT00010040779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023743.1", "url": "https://www.ensembl.org/id/ENSGALP00010023743.1" } ] } }, { "isoform_ac": "A0A8V0YYM2-1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1/entry#A0A8V0YYM2-1", "sequence": { "sequence": "MVLESLARIVKVQLPAYLKRLPLPESVGGFLRLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEQGHS", "length": 137, "header": "tr|A0A8V0YYM2-1|R4GLS1_CHICK Computationally mapped isoform of CDGSH iron-sulfur domain-containing protein 2 OS=Gallus gallus OX=9031 GN=CISD2 PE=1 SV=1 CANONICAL=R4GLS1-1" }, "locus": { "chromosome": "4", "start_pos": 60469759, "end_pos": 60463265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040784.1", "url": "https://www.ensembl.org/id/ENSGALT00010040784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023748.1", "url": "https://www.ensembl.org/id/ENSGALP00010023748.1" } ] } }, { "isoform_ac": "R4GLS1-1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1/entry#R4GLS1-1", "sequence": { "sequence": "MVLESLARIVKVQLPAYLKRLPLPESVGGFLRLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV", "length": 134, "header": "tr|R4GLS1-1|R4GLS1_CHICK Isoform 1 of CDGSH iron-sulfur domain-containing protein 2 OS=Gallus gallus OX=9031 GN=CISD2 PE=1 SV=1 CANONICAL=R4GLS1-1" }, "locus": { "chromosome": "4", "start_pos": 60469315, "end_pos": 60463265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040788.1", "url": "https://www.ensembl.org/id/ENSGALT00010040788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023752.1", "url": "https://www.ensembl.org/id/ENSGALP00010023752.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422714", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LB68-1", "protein_name": "CDGSH iron-sulfur domain-containing protein 2", "gene_name": "Cisd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLDSVARIVKVQLPAYLKQLPLPDSITGFARLTVAEWLRLLPFLGVLALLGYLAVRPFFPKKKQQKDSLINLKIQKENPKVVNEINIEDLNLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILRKKEV", "length": 135 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S108-1", "protein_name": "CDGSH iron-sulfur domain-containing protein 2", "gene_name": "CISD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLECVARIVKVQLPAYLKRLPIPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV", "length": 135 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7T326-1", "protein_name": "CDGSH iron-sulfur domain-containing protein 2", "gene_name": "cisd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLESISKIIKIQLPAYLKKLPLPETIGGFARLTVSEWLRLLPLLGILALLGYLTIRPFLPKKKKQRDSLINLKIQKENPKVVNEIDIEDLRTPNVCYCRCWRSKTFPVCDKSHIKHNELTGDNVGPLILKKKTL", "length": 135 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N5K1-1", "protein_name": "CDGSH iron-sulfur domain-containing protein 2", "gene_name": "CISD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV", "length": 135 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQB5-1", "protein_name": "CDGSH iron-sulfur domain-containing protein 2", "gene_name": "Cisd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLDSVARIVKVQLPAYLKQLPVPDSITGFARLTVSDWLRLLPFLGVLALLGYLAVRPFFPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV", "length": 135 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAM6-1", "protein_name": "CDGSH iron-sulfur domain protein", "gene_name": "Cisd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPISHLVKSSLPNYLSSLPVPDSIGGWFKLSFKDWLALIPPTVVVAGLGYTAYLAYCPAARASCAAKNSGRCNNHIRKNEPKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK", "length": 133 }, "evidence": [ { "id": "R4GLS1", "url": "https://omabrowser.org/oma/group/R4GLS1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "R4GLS1", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLS1" }, { "id": "SM00704", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00704" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Iron-binding zinc finger CDGSH type", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 119, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P5J8-1", "uniprot_ac": "F1P5J8", "uniprot_id": "F1P5J8_CHICK", "mass": { "chemical_mass": 44295.0, "monoisotopic_mass": 44295.0 }, "refseq": { "ac": "NP_001332924", "name": "N-acetylglucosamine-6-phosphate deacetylase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924" }, "gene_names": [ { "name": "AMDHD2", "type": "recommended", "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ] }, { "name": "AMDHD2", "type": "synonym", "evidence": [ { "id": "NP_001332924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924" } ] } ], "protein_names": [ { "name": "N-acetylglucosamine-6-phosphate deacetylase", "type": "recommended", "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.25", "type": "synonym", "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosamine-6-phosphate deacetylase", "type": "synonym", "evidence": [ { "id": "NP_001332924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924" } ] }, { "name": "putative N-acetylglucosamine-6-phosphate deacetylase", "type": "synonym", "evidence": [ { "id": "NP_001332924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267647.14915.1, SRR13267648.27893.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Sep 17, 2016 this sequence version replaced XP_001232228.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001332924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMDHD2", "url": "https://www.uniprot.org/uniprotkb/F1P5J8", "locus": { "chromosome": "14", "start_pos": 13890924, "end_pos": 13898064, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017468", "url": "https://www.ensembl.org/id/ENSGALG00010017468" } ] } } ], "crossref": [ { "id": "F1P5J8", "url": "https://alphafold.ebi.ac.uk/entry/F1P5J8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009234", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009234", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00854", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00854", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416754", "url": "https://www.ncbi.nlm.nih.gov/gene/416754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416754", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416754", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCRKGAH", "url": "https://omabrowser.org/oma/group/PCRKGAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0X9", "url": "https://www.orthodb.org/?gene=A0A8V0Z0X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P5J8", "url": "https://www.orthodb.org/?gene=F1P5J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11113:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11113:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001332924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001332924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22936", "url": "https://www.rhea-db.org/rhea/22936", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0X9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5J8-1", "url": "https://www.uniprot.org/uniprotkb/F1P5J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSNKSVSDAPIAQFTNCRLLRGRRLQREDLWVREGKILNPEKLFFDEKGSADVQLDCKGCILAPGFIDVQINGGFGVDFSLATDDFRSGIDLVGRKILSHGVTSFCPTLVTSPPSVYHQILPQIDVRNGGAHGAGVLGAHMEGPFISKEKKGAHPEHCIRTFEENAFQDLLATYGSLDCVRIVTLAPEIKRSSEVIRELTKRGICVSLGHSVANLSQAEEAVQHGATFITHLFNAMLPFHHRDPGIVGLLTSDKIPAGRRVFYGMISDGIHTNPAALRIAHRAHPKGMVLVTDAIAGMGLAPGRHTLGQQVVEIDGLNTYIAGTKTLSGSVATMDTCVRHFLEATGCSVETALEAASLHPAQLLGIEDRKGTLNYDSDADFLMLDDSLHVQATYIAGEEVWRRDALGM", "length": 409, "header": "tr|F1P5J8-1|F1P5J8_CHICK Isoform 1 of N-acetylglucosamine-6-phosphate deacetylase OS=Gallus gallus OX=9031 GN=AMDHD2 PE=1 SV=3 CANONICAL=F1P5J8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0X9-1", "url": "https://www.uniprot.org/uniprotkb/F1P5J8/entry#A0A8V0Z0X9-1", "sequence": { "sequence": "MPSNKSVSDAPIAQFTNCRLLRGRRLQREDLWVREGKILNPEKLFFDEKGSADVQLDCKGCILAPGFIDVQINGGFGVDFSLATDDFRSGIDLVGRKILSHGVTSFCPTLVTSPPSVYHQIDVRNGGAHGAGVLGAHMEGPFISKEKKGAHPEHCIRTFEENAFQDLLATYGSLDCVRIVTLAPEIKRSSEVIRELTKRGICVSLGHSVANLSQAEEAVQHGATFITHLFNAMLPFHHRDPGIVGLLTSDKIPAGRRVFYGMISDGIHTNPAALRIAHRAHPKGMVLVTDAIAGMGLAPGRHTLGQQVVEIDGLNTYIAGTKTLSGSVATMDTCVRHFLEATGCSVETALEAASLHPAQLLGIEDRKGTLNYDSDADFLMLDDSLHVQATYIAGEEVWRRDALGM", "length": 405, "header": "tr|A0A8V0Z0X9-1|F1P5J8_CHICK Computationally mapped isoform of N-acetylglucosamine-6-phosphate deacetylase OS=Gallus gallus OX=9031 GN=AMDHD2 PE=1 SV=1 CANONICAL=F1P5J8-1" }, "locus": { "chromosome": "14", "start_pos": 13897827, "end_pos": 13892209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042183.1", "url": "https://www.ensembl.org/id/ENSGALT00010042183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024714.1", "url": "https://www.ensembl.org/id/ENSGALP00010024714.1" } ] } }, { "isoform_ac": "F1P5J8-1", "url": "https://www.uniprot.org/uniprotkb/F1P5J8/entry#F1P5J8-1", "sequence": { "sequence": "MPSNKSVSDAPIAQFTNCRLLRGRRLQREDLWVREGKILNPEKLFFDEKGSADVQLDCKGCILAPGFIDVQINGGFGVDFSLATDDFRSGIDLVGRKILSHGVTSFCPTLVTSPPSVYHQILPQIDVRNGGAHGAGVLGAHMEGPFISKEKKGAHPEHCIRTFEENAFQDLLATYGSLDCVRIVTLAPEIKRSSEVIRELTKRGICVSLGHSVANLSQAEEAVQHGATFITHLFNAMLPFHHRDPGIVGLLTSDKIPAGRRVFYGMISDGIHTNPAALRIAHRAHPKGMVLVTDAIAGMGLAPGRHTLGQQVVEIDGLNTYIAGTKTLSGSVATMDTCVRHFLEATGCSVETALEAASLHPAQLLGIEDRKGTLNYDSDADFLMLDDSLHVQATYIAGEEVWRRDALGM", "length": 409, "header": "tr|F1P5J8-1|F1P5J8_CHICK Isoform 1 of N-acetylglucosamine-6-phosphate deacetylase OS=Gallus gallus OX=9031 GN=AMDHD2 PE=1 SV=3 CANONICAL=F1P5J8-1" }, "locus": { "chromosome": "14", "start_pos": 13897827, "end_pos": 13892209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042186.1", "url": "https://www.ensembl.org/id/ENSGALT00010042186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024717.1", "url": "https://www.ensembl.org/id/ENSGALP00010024717.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416754", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416754", "resource": "KEGG Pathway" }, { "id": "R-GGA-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I330-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "Amdhd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRGGQRAAGAPVRQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRMADEQQDCGGCILAPGFIDVQMNGGFGVDFSKATEDVGSGIALVARRILSHGVTSFCPTMVTSPPEIYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFEDNAFHDVLATYGALDNVRIVTLAPELNRSHEVIQALTAQGICVSLGHSVADLGAAEVAVQNGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPPGHCIFYGMIADGIHTNPAALRIAHRAHPRGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYVAGTKTLCGSIAPMDVCIRHFLQATGCSVESALEAASLHPAQLLGLEKTKGNLDFGADADFVVLDDTLHVQATYISGELVWKAEEAGP", "length": 409 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A7MBC0-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "AMDHD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGGQGAARAPVIQFTNCRILRGGALLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGCILAPGFIDVQINGGFGVDFSQASEDVGSGVALVARRILSHGVTSFCPTLVTSPLEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAHLRSFEADAFQDVLATYGGLDNVRIVTLAPELGHSQEVIRALTALGICVSLGHSVADLGTAEEAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRHIFYGMIADGIHTNPAALRIAHRAHPKGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLTAYVAGTNTLSGSIAPMDTCVRHFLQATGCSVESALEAASLHPAQLLGLEKRKGTLDFGADADFVVLDDSLHVRATYISGELVWQVEEARP", "length": 409 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P0U0-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "amdhd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPSNKSVSDAPITQFVNCRILKNHKLQWEDLWVREGKILNPEKLFFDEQGFADHRVDCENKIIAPGFIDVQLNGGYGIDFSQASSDIRGGVALVAKKILEHGVTSFCPTLVTSPPHIYHKVIPELRVQDGGPEGAGVLGIHLEGPFISEEKRGAHPPKFLRTFQSGGVADLMETYGQLENVAMVTLAPELTNSAAAIHELSSRGITVSVGHSMADLSQAEEAVQNGATFITHLFNAMLPFHHRDPGIVGLLTSDRIPPGRTVYYGMIADGIHTHPAALRIAHRAHPAGLVLVTDAVTAMGLPPGRHTLGQQQIDIQGLHAYVAGTTTLSGSIATMDMCVRHFREASGCTVEAALEAASLHPAQLLGISHRKGTLEFGADADFIVLDDMLTVRETYIAGQQVWRK", "length": 404 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8JZV7-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "Amdhd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSGQCAAGAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSKATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFEANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAQGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLGGSIAPMDVCVRHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELVWQAEEAGP", "length": 409 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VR81-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVRIKCNSEEPESPEQKILASSQRLLQFTNCRLVRDHRIIHDDLWVRDGRIVNPEPVFFDERTKAHCRIDCGGAIIAPGYIDLQINGGYGVDFSYDTETIEEGVATVARGLVKSGVTSFCPTLVTSPSDSYHTILPRIPAEVPKGAGILGIHAEGPFINPQKKGAHPEHCIQTIDKGLSTLKETYGSLERIKIITLAPEKVTDPEVIGQLVERGITVALGHSMASLSDGERAVQQGATLITHLFNAMLPFHHRDPGLVGLLASDAVPHGRTVYFGIISDGVHTHPAALRIAYRTHPQGLILVTDAISALGLEEGVHHIGQLPLQVKQGKAFIAGTETLCGSIAPMDECVRIFQKATDCSVVYAIEAATLHPAQCLKIEKQKGTLDFGSDADFVLLDDQLRVLSTWIAGVCVHRTVK", "length": 417 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y303-1", "protein_name": "N-acetylglucosamine-6-phosphate deacetylase", "gene_name": "AMDHD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGGRILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDNVRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEVEVDGLTAYVAGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLHVQATYISGELVWQADAARQ", "length": 409 }, "evidence": [ { "id": "F1P5J8", "url": "https://omabrowser.org/oma/group/F1P5J8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" }, { "name": "N-acetylneuraminate catabolic process", "id": "GO:0019262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019262", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" }, { "name": "negative regulation of UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0106279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106279", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" }, { "name": "N-acetylglucosamine catabolic process", "id": "GO:0006046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006046", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylglucosamine-6-phosphate deacetylase activity", "id": "GO:0008448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008448", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P5J8", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22936", "name": "", "equation": "N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5J8-1" ], "evidence": [ { "id": "22936", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22936" } ] }, { "id": "R-GGA-6803789", "name": "AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6803743" ], "output_participant_list": [ "R-ALL-193473" ], "enzyme_list": [ "F1P5J8-1" ], "evidence": [ { "id": "R-GGA-6803789", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803789" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-193473", "participant_name": "CCA [cytosol]", "crossref": [ { "id": "ZINC000006858022", "database": "ZINC", "url": "" }, { "id": "29747", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6803743", "participant_name": "GlcNGc-6-P [cytosol]", "crossref": [ { "id": "88130", "database": "ChEBI", "url": "" }, { "id": "ZINC000263614809", "database": "ZINC", "url": "" }, { "id": "ZINC000013515189", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1P5J8", "gene_name": "AMDHD2", "activity": [ { "ec_number": "3.5.1.25", "activity": "N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.", "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ] }, { "ec_number": "3.5.1.25", "activity": "", "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P5J8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 409, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P5J8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P5J8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" }, { "id": "PF01979", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amidohydrolase-related", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 400, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9#function" }, { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 139, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 139, "end_pos": 139, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8#function" }, { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 143, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 143, "end_pos": 143, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9#function" }, { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 207, "amino_acid": "Val", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 207, "end_pos": 207, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8#function" }, { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 211, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 211, "end_pos": 211, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9#function" }, { "id": "A0A8V0Z0X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0X9" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 228, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 228, "end_pos": 228, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8#function" }, { "id": "F1P5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5J8" }, { "id": "PIRSR038994-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038994-3" } ], "binding_site_uniprot": 232, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 232, "end_pos": 232, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.25", "ec_name": "N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.", "evidence": [ { "id": "3.5.1.25", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.25" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4X6-1", "uniprot_ac": "F1P4X6", "uniprot_id": "F1P4X6_CHICK", "mass": { "chemical_mass": 28272.0, "monoisotopic_mass": 28272.0 }, "refseq": { "ac": "NP_001012589", "name": "integral membrane protein 2A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012589" }, "gene_names": [ { "name": "ITM2A", "type": "recommended", "evidence": [ { "id": "F1P4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ] }, { "name": "ITM2A", "type": "synonym", "evidence": [ { "id": "NP_001012589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012589" } ] } ], "protein_names": [ { "name": "Integral membrane protein 2", "type": "recommended", "evidence": [ { "id": "F1P4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4X6/entry#names_and_taxonomy" } ] }, { "name": "integral membrane protein 2A", "type": "synonym", "evidence": [ { "id": "NP_001012589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012589" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851673.1, HAEL01000193.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_001012589.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012589" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITM2A", "url": "https://www.uniprot.org/uniprotkb/F1P4X6", "locus": { "chromosome": "4", "start_pos": 1425206, "end_pos": 1437464, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018035", "url": "https://www.ensembl.org/id/ENSGALG00010018035" } ] } } ], "crossref": [ { "id": "F1P4X6", "url": "https://alphafold.ebi.ac.uk/entry/F1P4X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004107", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004107", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422145", "url": "https://www.ncbi.nlm.nih.gov/gene/422145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422145", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMCYVGE", "url": "https://omabrowser.org/oma/group/QMCYVGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4U3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBT2", "url": "https://www.orthodb.org/?gene=A0A8V0ZBT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4X6", "url": "https://www.orthodb.org/?gene=F1P4X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10962", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10962", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10962:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10962:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4X6-1", "url": "https://www.uniprot.org/uniprotkb/F1P4X6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKIAFSSPFAQKGEPKKEASEALVADKDPEVATQGGENSSGRCLLTLLGLAFILAGVVVGGACIYKYFMPKHKVYRGEMCYFENENRDRAVEPYFLPIAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLDLQLGKCYVIPLNTSIVMPPRNLMDLFAKLATGSYLPQTYLVREEMVVTEEIDNVSDLGIFIYQLCVGKETFKLQRRDQIMGLQKRSVENCHSIRHFENSFVVETKICQQ", "length": 251, "header": "tr|F1P4X6-1|F1P4X6_CHICK Isoform 1 of Integral membrane protein 2 OS=Gallus gallus OX=9031 GN=ITM2A PE=1 SV=1 CANONICAL=F1P4X6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4U3-1", "url": "https://www.uniprot.org/uniprotkb/F1P4X6/entry#A0A8V0Z4U3-1", "sequence": { "sequence": "MSGHTFSVLIILCLKDPEVATQGGENSSGRCLLTLLGLAFILAGVVVGGACIYKYFMPKHKVYRGEMCYFENENRDRAVEPYFLPIAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLDLQLGKCYVIPLNTSIVMPPRNLMDLFAKLATGSYLPQTYLVREEMVVTEEIDNVSDLGIFIYQLCVGKETFKLQRRDQIMGLQKRSVENCHSIRHFENSFVVETKICQQ", "length": 238, "header": "tr|A0A8V0Z4U3-1|F1P4X6_CHICK Computationally mapped isoform of Integral membrane protein 2 OS=Gallus gallus OX=9031 GN=ITM2A PE=1 SV=1 CANONICAL=F1P4X6-1" }, "locus": { "chromosome": "4", "start_pos": 1431268, "end_pos": 1426183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043595.1", "url": "https://www.ensembl.org/id/ENSGALT00010043595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025929.1", "url": "https://www.ensembl.org/id/ENSGALP00010025929.1" } ] } }, { "isoform_ac": "A0A8V0ZBT2-1", "url": "https://www.uniprot.org/uniprotkb/F1P4X6/entry#A0A8V0ZBT2-1", "sequence": { "sequence": "MHLSTCDPEVATQGGENSSGRCLLTLLGLAFILAGVVVGGACIYKYFMPKHKVYRGEMCYFENENRDRAVEPYFLPIAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLDLQLGKCYVIPLNTSIVMPPRNLMDLFAKLATGSYLPQTYLVREEMVVTEEIDNVSDLGIFIYQLCVGKETFKLQRRDQIMGLQKRSVENCHSIRHFENSFVVETKICQQ", "length": 229, "header": "tr|A0A8V0ZBT2-1|A0A8V0ZBT2_CHICK Computationally mapped isoform of Integral membrane protein 2 OS=Gallus gallus OX=9031 GN=ITM2A PE=1 SV=1 CANONICAL=F1P4X6-1" }, "locus": { "chromosome": "4", "start_pos": 1436765, "end_pos": 1426183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043604.1", "url": "https://www.ensembl.org/id/ENSGALT00010043604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025936.1", "url": "https://www.ensembl.org/id/ENSGALP00010025936.1" } ] } }, { "isoform_ac": "F1P4X6-1", "url": "https://www.uniprot.org/uniprotkb/F1P4X6/entry#F1P4X6-1", "sequence": { "sequence": "MVKIAFSSPFAQKGEPKKEASEALVADKDPEVATQGGENSSGRCLLTLLGLAFILAGVVVGGACIYKYFMPKHKVYRGEMCYFENENRDRAVEPYFLPIAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLDLQLGKCYVIPLNTSIVMPPRNLMDLFAKLATGSYLPQTYLVREEMVVTEEIDNVSDLGIFIYQLCVGKETFKLQRRDQIMGLQKRSVENCHSIRHFENSFVVETKICQQ", "length": 251, "header": "tr|F1P4X6-1|F1P4X6_CHICK Isoform 1 of Integral membrane protein 2 OS=Gallus gallus OX=9031 GN=ITM2A PE=1 SV=1 CANONICAL=F1P4X6-1" }, "locus": { "chromosome": "4", "start_pos": 1434157, "end_pos": 1426183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043600.1", "url": "https://www.ensembl.org/id/ENSGALT00010043600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025932.1", "url": "https://www.ensembl.org/id/ENSGALP00010025932.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422145", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422145", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H2B5-1", "protein_name": "Integral membrane protein 2", "gene_name": "Itm2a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILAGKELKVAEQEKDGSSGRCMLTLLGMSFILAGLIVGGACIYKYFMPKNTIYHGEMCFFDSEDPVNSVRGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE", "length": 263 }, "evidence": [ { "id": "F1P4X6", "url": "https://omabrowser.org/oma/group/F1P4X6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "K7GMP3-1", "protein_name": "Integral membrane protein 2", "gene_name": "ITM2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVKIAFNTPAAVQKEEAQQDVEALVSHTVRAQILTGKELQVATKEKEGFSGRCMLTLVGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSADPANFLQGGEPYFLPVMEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMPPKYLVELFGKLARGKYLPHTYVVHEDLVAVEEIHDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE", "length": 263 }, "evidence": [ { "id": "F1P4X6", "url": "https://omabrowser.org/oma/group/F1P4X6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43736-1", "protein_name": "Integral membrane protein 2A", "gene_name": "ITM2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKIAFNTPTAVQKEEARQDVEALLSRTVRTQILTGKELRVATQEKEGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYRGEMCFFDSEDPANSLRGGEPNFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMPPKNLVELFGKLASGRYLPQTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE", "length": 263 }, "evidence": [ { "id": "F1P4X6", "url": "https://omabrowser.org/oma/group/F1P4X6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61500-1", "protein_name": "Integral membrane protein 2A", "gene_name": "Itm2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE", "length": 263 }, "evidence": [ { "id": "F1P4X6", "url": "https://omabrowser.org/oma/group/F1P4X6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of amyloid precursor protein biosynthetic process", "id": "GO:0042985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042985", "evidence": [ { "database": "UniProtKB", "id": "F1P4X6", "url": "https://www.uniprot.org/uniprotkb/F1P4X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4X6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 251, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4X6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4X6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z753-1", "uniprot_ac": "A0A8V0Z753", "uniprot_id": "A0A8V0Z753_CHICK", "mass": { "chemical_mass": 63105.0, "monoisotopic_mass": 63105.0 }, "refseq": { "ac": "XP_015150213", "name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150213" }, "gene_names": [ { "name": "NAGPA", "type": "recommended", "evidence": [ { "id": "A0A8V0Z753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753" } ] }, { "name": "NAGPA", "type": "synonym", "evidence": [ { "id": "XP_015150213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150213" } ] } ], "protein_names": [ { "name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "type": "synonym", "evidence": [ { "id": "XP_015150213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150213" }, { "id": "A0A8V0Z753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150213" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z753", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAGPA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753", "locus": { "chromosome": "14", "start_pos": 13374083, "end_pos": 13384393, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018673", "url": "https://www.ensembl.org/id/ENSGALG00010018673" } ] } } ], "crossref": [ { "id": "A0A8V0Z753", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z753", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000046787", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000046787", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416395", "url": "https://www.ncbi.nlm.nih.gov/gene/416395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416395", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416395", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPCKCEH", "url": "https://omabrowser.org/oma/group/RPCKCEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3ABE7", "url": "https://www.orthodb.org/?gene=A0A3Q3ABE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z753", "url": "https://www.orthodb.org/?gene=A0A8V0Z753", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8N9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40446", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40446", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40446:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40446:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3ABE7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ABE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ABE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ABE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z753", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASARAGAAGRRRWALAVAAALTALGWLQAAGGAGAASGQRLLQPYPPGRHGPRHGHRHVRACQPVRHGNVTHEAWPGDNSTGLPTATTRTFVSYVPSAEERRRAVYGHFTFVRNPLRTFSVLEPGGAGGCGEQRRVPVEETARLGRCLVAQNGGYFDMSSGECLGNVVSDGRLVQNAHGLQNAQFGIRRDGTMVFGYLSEEDVLDQANPFVQLVSGVVWLLRDGEVYINQSQIAECDETQTTGTFEKFINVISARTAVGHDSQGQLVLVHVDGQTESRGINLWEMAEFLKQQGIINAINLDGGGSATLVLNGTLASYPSEHCSFDNMWRCPRSISTIVCVHEPACEPADCSGHGDCVQGQCHCAGDFWRGPACDTLDCGPSNCSLHGTCTASGCLCDAGWVGSNCSEACASGFYGNACSQKCQCQNGGLCDPVHGACSCPAGYYGTSCEHACPMGWYGPNCQQLCACEHSCPCNPQTGSCNITYELAIQDQLNRAWRCLASPDKEKSNEKFSLSERTWISVTFVLALLLAISAMGNVGLFLKARSEGQHGGGDYRYHPLREMNGEASHTFTSAACEAEDAQDQSQTLL", "length": 590, "header": "tr|A0A8V0Z753-1|A0A8V0Z753_CHICK Isoform 1 of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGPA PE=4 SV=1 CANONICAL=A0A8V0Z753-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3ABE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753/entry#A0A3Q3ABE7-1", "sequence": { "sequence": "MRALRDPAVLSCRAASGQRLLQPYPPGRHGPRHGHRHVRACQPVRHGNVTHEAWPGDNSTGLPTATTRTFVSYVPSAEERRRAVYGHFTFVRNPLRTFSVLEPGGAGGCGEQRRVPVEETARLGRCLVAQNGGYFDMSSGECLGNVVSDGRLVQNAHGLQNAQFGIRRDGTMVFGYLSEEDVLDQANPFVQLVSGVVWLLRDGEVYINQSQIAECDETQTTGTFEKFINVISARTAVGHDSQGQLVLVHVDGQTESRGINLWEMAEFLKQQGIINAINLDGGGSATLVLNGTLASYPSEHCSFDNMWRCPRSISTIVCVHEPACEPADCSGHGDCVQGQCHCAGDFWRGPACDTLDCGPSNCSLHGTCTASGCLCDAGWVGSNCSEACASGFYGNACSQKCQCQNGGLCDPVHGACSCPAGYYGTSCEHACPMGWYGPNCQQLCACEHSCPCNPQTGSCNITYELAIQDQLNRAWRCLASPDKEKSNEKFSLSERTWISVTFVLALLLAISAMGNVGLFLKARSEGQHGGGDYRYHPLREMNGEASHTFTSAACEAEDAQDQSQTLL", "length": 567, "header": "tr|A0A3Q3ABE7-1|A0A8V0Z753_CHICK Computationally mapped isoform of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGPA PE=4 SV=1 CANONICAL=A0A8V0Z753-1" }, "locus": { "chromosome": "14", "start_pos": 13384176, "end_pos": 13375428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045155.1", "url": "https://www.ensembl.org/id/ENSGALT00010045155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026968.1", "url": "https://www.ensembl.org/id/ENSGALP00010026968.1" } ] } }, { "isoform_ac": "A0A8V0Z753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753/entry#A0A8V0Z753-1", "sequence": { "sequence": "MAASARAGAAGRRRWALAVAAALTALGWLQAAGGAGAASGQRLLQPYPPGRHGPRHGHRHVRACQPVRHGNVTHEAWPGDNSTGLPTATTRTFVSYVPSAEERRRAVYGHFTFVRNPLRTFSVLEPGGAGGCGEQRRVPVEETARLGRCLVAQNGGYFDMSSGECLGNVVSDGRLVQNAHGLQNAQFGIRRDGTMVFGYLSEEDVLDQANPFVQLVSGVVWLLRDGEVYINQSQIAECDETQTTGTFEKFINVISARTAVGHDSQGQLVLVHVDGQTESRGINLWEMAEFLKQQGIINAINLDGGGSATLVLNGTLASYPSEHCSFDNMWRCPRSISTIVCVHEPACEPADCSGHGDCVQGQCHCAGDFWRGPACDTLDCGPSNCSLHGTCTASGCLCDAGWVGSNCSEACASGFYGNACSQKCQCQNGGLCDPVHGACSCPAGYYGTSCEHACPMGWYGPNCQQLCACEHSCPCNPQTGSCNITYELAIQDQLNRAWRCLASPDKEKSNEKFSLSERTWISVTFVLALLLAISAMGNVGLFLKARSEGQHGGGDYRYHPLREMNGEASHTFTSAACEAEDAQDQSQTLL", "length": 590, "header": "tr|A0A8V0Z753-1|A0A8V0Z753_CHICK Isoform 1 of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGPA PE=4 SV=1 CANONICAL=A0A8V0Z753-1" }, "locus": { "chromosome": "14", "start_pos": 13384364, "end_pos": 13375428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045179.1", "url": "https://www.ensembl.org/id/ENSGALT00010045179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026980.1", "url": "https://www.ensembl.org/id/ENSGALP00010026980.1" } ] } }, { "isoform_ac": "A0A8V0Z8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753/entry#A0A8V0Z8N9-1", "sequence": { "sequence": "MRALRDPAVLSCRAASGQRLLQPYPPGRHGPRHGHRHVRACQPVRHGNVTHEAWPGDNSTGLPTATTRTFVSYVPSAEERRRAVYGHFTFVRNPLRTFSVLEPGGAGGCGEQRRVPVEETARLGRCLVAQNGGYFDMSSGECLGNVVSDGRLVQNAHGLQNAQFGIRRDGTMVFGYLSEEDVLDQANPFVQLVSGVVWLLRDGEVYINQSQIAECDETQTTGTFEKFINVISARTAVGHDSQGQLVLVHVDGQTESRGINLWEMAEFLKQQGIINAINLDGGGSATLVLNGTLASYPSEHCSFDNMWRCPRSISTIVCVHEPACEPADCSGHGDCVQGQCHCAGDFWRGPACDTLDCGPSNCSLHGTCTASGCLCDAGWVGSNCSEACPMGWYGPNCQQLCACEHSCPCNPQTGSCNITYELAIQDQLNRAWRCLASPDKEKSNEKFSLSERTWISVTFVLALLLAISAMGNVGLFLKARSEGQHGGGDYRYHPLREMNGEASHTFTSAACEAEDAQDQSQTLL", "length": 524, "header": "tr|A0A8V0Z8N9-1|A0A8V0Z8N9_CHICK Computationally mapped isoform of N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGPA PE=4 SV=1 CANONICAL=A0A8V0Z753-1" }, "locus": { "chromosome": "14", "start_pos": 13384176, "end_pos": 13375428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045170.1", "url": "https://www.ensembl.org/id/ENSGALT00010045170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026976.1", "url": "https://www.ensembl.org/id/ENSGALP00010026976.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416395", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RK92-1", "protein_name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "gene_name": "NAGPA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASIGRCLLFLIALCHFLGEASGYLGLGASRDDDLLLPYPRARTRFSRDCTRVRAGRREHESWLPSSATPSARGPSVRTFVSHFSGRAVAGHLTRAAEPLRTFSVLEPGGPGGCASRRRVTVEETAREAGCSVAQNGGFFRMDTGECLGNVVSDGRLVGNAEGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIHINESQAAECDETQETGSFSKFINVISARTAVGHDRKGQLVLFHVDGQTEQRGINLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRSVSTVVCVHEPRCQPPDCSGHGTCVEGHCQCVGSFWRGAACDELDCGPANCSQHGLCTETGCRCEAGWTGSNCSEACTNGFFGEDCAKKCQCHNGATCDPIQGTCACPPGFTGDTCVQECPLGWYGPGCQSPCKCEHQCPCDPQTGNCSLTWSPTLNSLLSQVKQCLPPPGATLKTEELSVSTRTTWLALTLALVFLLLISMAANVSLFLGSRAKRSRHLVGAYAYHPLQETNGELLAVEKEQPGDTCNPFKD", "length": 569 }, "evidence": [ { "id": "A0A8V0Z753", "url": "https://omabrowser.org/oma/group/A0A8V0Z753/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V6D1-1", "protein_name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "gene_name": "Nagpa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPRGPGLFFKPALLGLLGVAWCSLGFGVSRDDDLLLPYPLARRRPSRDCARVHAGSPEQESWPPPPTNPGASHRAAVRTFVSHFEGRAVAGHLTRVADPLRTFSVLEPGGPGGCAQRRRATVEDTAVPAGCRVAQNGGFFRMGTGECLGNVVSDGRLVSSSGGLQNAQFGIRRDGTLVTGYLSEEDVLDTVNPFVQLLSGVVWLIRNGSIYINESQITECDETQETGSFSKFVNVMSARTAVGHDRKGQLILFHADGQTEQRGLNLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEPRCQPPNCSGHGTCVDGRCECTSHFWHGEACSELNCGPSNCSQHGLCTETGCRCDAGWTGSNCSEECPLGWYGPGCQRPCQCEHQRPCDPQTGNCSISQVKQCLQSTEAPPRAGGLASFTGTTWLALTLILIFLLLISTAVNVSLLLGSRAERNRHLDGDYVYHPLQEVNGDALAAEKEQTEETCNPFKD", "length": 517 }, "evidence": [ { "id": "A0A8V0Z753", "url": "https://omabrowser.org/oma/group/A0A8V0Z753/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P68827-1", "protein_name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "gene_name": "NAGPA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSMGRFLLFFIALRGFLLEASGDFGSGASRDDDVLLPYSRARARLARDCTRVHAGRLEHHESWPPAAQTAGAHRPSVRTFVSYFADRAVPGHLTRAPEPLRTFSVLEPGGPGGCASKRRATVEETARPSGCTVAQNGGFFRMETGECLGNVVSGGRRVSSAGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQAAECEETQETGSFNRFVNVISARTAVGHDRKGQLVLLHVDGQTEQRGINLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRRVSTVVCVHEPRCQPPDCSGHGTCMEGRCQCTGHFWRGAACDKLDCGPANCSQHGLCTETGCRCEAGWTGSNCSEECPLGWYGPGCQSPCKCEHQCPCDPQTGNCSVNWSPTLSSLFSRVKECFPPPEVTVQAEELSLLTRTTWLAITLALAFLLLISTAANVSLFLGSRAARRRHLDGAYVYHPLQEVNGEHPAAEKEQLGDSSNPFKD", "length": 527 }, "evidence": [ { "id": "A0A8V0Z753", "url": "https://omabrowser.org/oma/group/A0A8V0Z753/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BJ48-1", "protein_name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "gene_name": "Nagpa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPRGPGLFLIPALLGLLGVAWCSLSFGVSRDDDLLLPYPLARRRPSRDCARVRSGSPEQESWPPPPTNPGASHHAAVRTFVSHFEGRAVAGHLTRVADPLRTFSVLEPGGAGGCAQKRRATVEDTAVPAGCRIAQNGGFFRMSTGECLGNVVSDGRLVSSSGGLQNAQFGIRRDGTIVTGYLSEEEVLDPVNPFVQLLSGVVWLIRNGNIYINESQAIECDETQETGSFSKFVNVMSARTAVGHDREGQLILFHADGQTEQRGLNLWEMAEFLRQQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCSGHGTCVDGHCECTSHFWRGEACSELDCGPSNCSQHGLCTETGCHCDAGWTGSNCSEECPLGWYGPGCQRPCQCEHQCSCDPQTGNCSISQVRQCLQPTEATPRAGELASFTRTTWLALTLTLIFLLLISTGVNVSLFLGSRAERNRHLDGDYVYHPLQEVNGEALTAEKEHMEETSNPFKD", "length": 517 }, "evidence": [ { "id": "A0A8V0Z753", "url": "https://omabrowser.org/oma/group/A0A8V0Z753/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK23-1", "protein_name": "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase", "gene_name": "NAGPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSTGRWLLLRLALFGFLWEASGGLDSGASRDDDLLLPYPRARARLPRDCTRVRAGNREHESWPPPPATPGAGGLAVRTFVSHFRDRAVAGHLTRAVEPLRTFSVLEPGGPGGCAARRRATVEETARAADCRVAQNGGFFRMNSGECLGNVVSDERRVSSSGGLQNAQFGIRRDGTLVTGYLSEEEVLDTENPFVQLLSGVVWLIRNGSIYINESQATECDETQETGSFSKFVNVISARTAIGHDRKGQLVLFHADGQTEQRGINLWEMAEFLLKQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCHGHGTCVDGHCQCTGHFWRGPGCDELDCGPSNCSQHGLCTETGCRCDAGWTGSNCSEECPLGWHGPGCQRPCKCEHHCPCDPKTGNCSVSRVKQCLQPPEATLRAGELSFFTRTAWLALTLALAFLLLISTAANLSLLLSRAERNRRLHGDYAYHPLQEMNGEPLAAEKEQPGGAHNPFKD", "length": 515 }, "evidence": [ { "id": "A0A8V0Z753", "url": "https://omabrowser.org/oma/group/A0A8V0Z753/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "secretion of lysosomal enzymes", "id": "GO:0033299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033299", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z753", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z753", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z753" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 451, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 231, "end_pos": 233 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R9PXQ3-1", "uniprot_ac": "R9PXQ3", "uniprot_id": "R9PXQ3_CHICK", "mass": { "chemical_mass": 61237.0, "monoisotopic_mass": 61237.0 }, "refseq": {}, "gene_names": [ { "name": "TYR", "type": "recommended", "evidence": [ { "id": "R9PXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ] } ], "protein_names": [ { "name": "Tyrosinase", "type": "recommended", "evidence": [ { "id": "R9PXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3/entry#names_and_taxonomy" } ] }, { "name": "1.14.18.1", "type": "synonym", "evidence": [ { "id": "R9PXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3/entry#names_and_taxonomy" } ] }, { "name": "Monophenol monooxygenase", "type": "synonym", "evidence": [ { "id": "R9PXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TYR", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3", "locus": { "chromosome": "1", "start_pos": 187752869, "end_pos": 187810203, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007864", "url": "https://www.ensembl.org/id/ENSGALG00010007864" } ] } } ], "crossref": [ { "id": "R9PXQ3", "url": "https://alphafold.ebi.ac.uk/entry/R9PXQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XYW8", "url": "https://www.orthodb.org/?gene=A0A8V0XYW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R9PXQ3", "url": "https://www.orthodb.org/?gene=R9PXQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11474", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11474", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11474:SF124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11474:SF124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5662702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5662702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XYW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R9PXQ3-1", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSCCSVRMFLFAMGLLLVILQPSTGQFPRVCANTQSLLRKECCPPWDGDGTPCGERSNRGTCQRILLSQAPLGPQFPFSGVDDREDWPSVFYNRTCRCRGNFMGFNCGECKFGFSGQNCTERRLRTRRNIFQLTISEKDKFLAYLNLAKNIPSKDYVIATGTYAQMNNGSNPMFRNINVYDLFVWMHYYASRDTLLGGSNVWRDIDFAHEAPGFLPWHRAFLLLWEREIQKITGDENFTIPYWDWRDAEDCVICTDEYMGGQHPTNPNLLSPASFFSSWQVICTQSEEYNSQQALCNATSEGPILRNPGNNDKSRTPRLPSSSEVEFCLTLTQYESGSMDKMANYSFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFERWLRRHRPMLEVYPAANAPIGHNRENYMVPFIPLYRNGEFFISSRELGYDYEYLQEPALGSFQDFLIPYLKQAHQIWPWLVGAAVIGGIITAVLSGLILACRKKRKGTSPEIQPLLTESEDYNNVSYQSHF", "length": 537, "header": "tr|R9PXQ3-1|R9PXQ3_CHICK Isoform 1 of Tyrosinase OS=Gallus gallus OX=9031 GN=TYR PE=3 SV=3 CANONICAL=R9PXQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XYW8-1", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3/entry#A0A8V0XYW8-1", "sequence": { "sequence": "MLSCCSVRMFLFAMGLLLVILQPSTGQFPRVCANTQSLLRKECCPPWDGDGTPCGERSNRGTCQRILLSQAPLGPQFPFSGVDDREDWPSVFYNRTCRCRGNFMGFNCGECKFGFSGQNCTERRLRTRRNIFQLTISEKDKFLAYLNLAKNIPSKDYVIATGTYAQMNNGSNPMFRNINVYDLFVWMHYYASRDTLLGGSNVWRDIDFAHEAPGFLPWHRAFLLLWEREIQKITGDENFTIPYWDWRDAEDCVICTDEYMGGQHPTNPNLLSPASFFSSWQVICTQSEEYNSQQALCNATSEGPILRNPGNNDKSRTPRLPSSSEVEFCLTLTQYESGSMDKMANYSFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFERWLRRHRPMLEVYPAANAPIGHNRENYMVPFIPLYRNGEFFISSRELGYDYEYLQEPVCLLMEMYSSACCVKLCVSLQFIGGRGGSLIYVYPV", "length": 499, "header": "tr|A0A8V0XYW8-1|R9PXQ3_CHICK Computationally mapped isoform of Tyrosinase OS=Gallus gallus OX=9031 GN=TYR PE=3 SV=1 CANONICAL=R9PXQ3-1" }, "locus": { "chromosome": "1", "start_pos": 187810058, "end_pos": 187765613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018717.1", "url": "https://www.ensembl.org/id/ENSGALT00010018717.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010267.1", "url": "https://www.ensembl.org/id/ENSGALP00010010267.1" } ] } }, { "isoform_ac": "R9PXQ3-1", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3/entry#R9PXQ3-1", "sequence": { "sequence": "MLSCCSVRMFLFAMGLLLVILQPSTGQFPRVCANTQSLLRKECCPPWDGDGTPCGERSNRGTCQRILLSQAPLGPQFPFSGVDDREDWPSVFYNRTCRCRGNFMGFNCGECKFGFSGQNCTERRLRTRRNIFQLTISEKDKFLAYLNLAKNIPSKDYVIATGTYAQMNNGSNPMFRNINVYDLFVWMHYYASRDTLLGGSNVWRDIDFAHEAPGFLPWHRAFLLLWEREIQKITGDENFTIPYWDWRDAEDCVICTDEYMGGQHPTNPNLLSPASFFSSWQVICTQSEEYNSQQALCNATSEGPILRNPGNNDKSRTPRLPSSSEVEFCLTLTQYESGSMDKMANYSFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFERWLRRHRPMLEVYPAANAPIGHNRENYMVPFIPLYRNGEFFISSRELGYDYEYLQEPALGSFQDFLIPYLKQAHQIWPWLVGAAVIGGIITAVLSGLILACRKKRKGTSPEIQPLLTESEDYNNVSYQSHF", "length": 537, "header": "tr|R9PXQ3-1|R9PXQ3_CHICK Isoform 1 of Tyrosinase OS=Gallus gallus OX=9031 GN=TYR PE=3 SV=3 CANONICAL=R9PXQ3-1" }, "locus": { "chromosome": "1", "start_pos": 187810058, "end_pos": 187753123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018719.1", "url": "https://www.ensembl.org/id/ENSGALT00010018719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010269.1", "url": "https://www.ensembl.org/id/ENSGALP00010010269.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5662702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5662702", "resource": "Reactome", "description": "Melanin biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "tyrosinase activity", "id": "GO:0004503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004503", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "melanin biosynthetic process", "id": "GO:0042438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042438", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "pigmentation", "id": "GO:0043473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043473", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "response to blue light", "id": "GO:0009637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009637", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "R9PXQ3", "url": "https://www.uniprot.org/uniprotkb/R9PXQ3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "melanosome membrane, melanosome lumen", "input_participant_list": [ "R-ALL-5668566", "R-ALL-5668567" ], "output_participant_list": [], "enzyme_list": [ "R9PXQ3-1" ], "evidence": [ { "id": "R-GGA-5662662", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5662662" } ] }, { "id": "R-GGA-5662692", "name": "Dopa is oxidized to dopaquinone by TYR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "melanosome lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R9PXQ3-1" ], "evidence": [ { "id": "R-GGA-5662692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5662692" } ] }, { "id": "R-GGA-5663050", "name": "DHI and DHICA polymerize forming eumelanin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"Z", "start_pos": 72371778, "end_pos": 72303889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022025.1", "url": "https://www.ensembl.org/id/ENSGALT00010022025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012628.1", "url": "https://www.ensembl.org/id/ENSGALP00010012628.1" } ] } }, { "isoform_ac": "F1P3Y8-1", "url": "https://www.uniprot.org/uniprotkb/F1P3Y8/entry#F1P3Y8-1", "sequence": { "sequence": "MERESSGAAGPSAGEEGEGCAGLWELPVERCERRPECSRCSRPQKVCLCPFLPIHPLKISTCLYIIQHPAEESRVLRTVPLLAACLPPDKCKILVGRRFSEDRYPELAAVCRNPSTLILYPGAEATNLEEVTVMSSGPPVMIIIDGTWSQAKDIFYKNSLFRFPRQVQLKTNISSQYVIRTQPTNNCLSTLECAAVALTIMEKNKSIQEIILRPLQALCSFQLQHGAQIHHSKEHLLKNGLYDKPMPKNKRKLRRMELLLNNVKI", "length": 265, "header": "tr|F1P3Y8-1|F1P3Y8_CHICK Isoform 1 of tRNA-uridine aminocarboxypropyltransferase OS=Gallus gallus OX=9031 GN=DTWD2 PE=3 SV=1 CANONICAL=F1P3Y8-1" }, "locus": { "chromosome": "Z", "start_pos": 72371778, "end_pos": 72300289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022030.1", "url": "https://www.ensembl.org/id/ENSGALT00010022030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012631.1", "url": "https://www.ensembl.org/id/ENSGALP00010012631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y8", "url": "https://www.uniprot.org/uniprotkb/F1P3Y8" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y8", "url": "https://www.uniprot.org/uniprotkb/F1P3Y8" } ], "pmid": "" }, { "name": "glycoRNA biosynthetic process", "id": "GO:0141217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141217", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y8", "url": "https://www.uniprot.org/uniprotkb/F1P3Y8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tRNA-uridine aminocarboxypropyltransferase activity", "id": "GO:0016432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016432", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y8", "url": "https://www.uniprot.org/uniprotkb/F1P3Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "62432", "name": "", "equation": "a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U7Z9-1", "F1P3Y8-1" ], "evidence": [ { "id": "62432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62432" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2U7Z9", "gene_name": "DTWD1", "activity": [ { "ec_number": "2.5.1.25", "activity": "a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+).", "evidence": [ { "id": "A0A3Q2U7Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z9" } ] }, { "ec_number": "2.5.1.25", "activity": "", "evidence": [ { "id": "A0A3Q2U7Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7Z9" } ] } ] }, { "uniprot_ac": "F1P3Y8", "gene_name": "DTWD2", "activity": [ { "ec_number": "2.5.1.25", "activity": "a uridine in tRNA + S-adenosyl-L-methionine = a 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"id": "2.5.1.25", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.25" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "V9GWR3-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQACKPHHPNTEPVLGLTQTPISQQSLPLHMIPSSQVDDLTSPAKRKRTSSPTKNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS", "length": 1453, "header": "tr|V9GWR3-1|V9GWR3_CHICK Isoform 1 of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4L7-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0Y4L7-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQLSTFHEHQLKTFSTNFPLFHLKVCNCHFNFSS", "length": 250, "header": "tr|A0A8V0Y4L7-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110965233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027307.1", "url": "https://www.ensembl.org/id/ENSGALT00010027307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015561.1", "url": "https://www.ensembl.org/id/ENSGALP00010015561.1" } ] } }, { "isoform_ac": "A0A8V0Y9C8-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0Y9C8-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLVSQINKWMHKYIICKAVVGCLGTPLYEYRELSDSNGGLGYV", "length": 1433, "header": "tr|A0A8V0Y9C8-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110914121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027322.1", "url": "https://www.ensembl.org/id/ENSGALT00010027322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015576.1", "url": "https://www.ensembl.org/id/ENSGALP00010015576.1" } ] } }, { "isoform_ac": "A0A8V0Y9D2-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0Y9D2-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQACKPHHPNTEPVLGLTQTPISQQSLPLHMIPSSQVDDLTSPAKRKRTSSPTKNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLRSPGDHNWIRWRWEESGQ", "length": 1462, "header": "tr|A0A8V0Y9D2-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110913928, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027327.1", "url": "https://www.ensembl.org/id/ENSGALT00010027327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015581.1", "url": "https://www.ensembl.org/id/ENSGALP00010015581.1" } ] } }, { "isoform_ac": "A0A8V0YAU2-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0YAU2-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQTYVTEPWEI", "length": 227, "header": "tr|A0A8V0YAU2-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110966968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027304.1", "url": "https://www.ensembl.org/id/ENSGALT00010027304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015558.1", "url": "https://www.ensembl.org/id/ENSGALP00010015558.1" } ] } }, { "isoform_ac": "A0A8V0YAU7-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0YAU7-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQAGCITPWISLETRQPRKVMLYSISRNL", "length": 245, "header": "tr|A0A8V0YAU7-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110958523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027310.1", "url": "https://www.ensembl.org/id/ENSGALT00010027310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015564.1", "url": "https://www.ensembl.org/id/ENSGALP00010015564.1" } ] } }, { "isoform_ac": "A0A8V0YAX4-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0YAX4-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS", "length": 1356, "header": "tr|A0A8V0YAX4-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110911946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027335.1", "url": "https://www.ensembl.org/id/ENSGALT00010027335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015589.1", "url": "https://www.ensembl.org/id/ENSGALP00010015589.1" } ] } }, { "isoform_ac": "A0A8V0YD37-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0YD37-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQACKPHHPNTEPVLGLTQTPISQQSLPLHMIPSSQVDDLTSPAKRKRTSSPTKNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLVSQINKWMHKYIICKAVVGCLGTPLYEYRELSDSNGGLGYV", "length": 1440, "header": "tr|A0A8V0YD37-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110914121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027316.1", "url": "https://www.ensembl.org/id/ENSGALT00010027316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015570.1", "url": "https://www.ensembl.org/id/ENSGALP00010015570.1" } ] } }, { "isoform_ac": "A0A8V0YD52-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#A0A8V0YD52-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS", "length": 1401, "header": "tr|A0A8V0YD52-1|V9GWR3_CHICK Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110911946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027331.1", "url": "https://www.ensembl.org/id/ENSGALT00010027331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015585.1", "url": "https://www.ensembl.org/id/ENSGALP00010015585.1" } ] } }, { "isoform_ac": "V9GWR3-1", "url": "https://www.uniprot.org/uniprotkb/V9GWR3/entry#V9GWR3-1", "sequence": { "sequence": "MKSCGVSLAAAAASAAPFGDEEKKMAAGKASGQSEEDFASLTAEEREALSGLDSRLFGFLRLHEDGARTKALLLKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEALYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDCNPCTLSNAEIQFHIAHLYEIQRKYHSAKEAYEQLLQIENLPAQVKATVLQQLGWMHHTVDQLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQACKPHHPNTEPVLGLTQTPISQQSLPLHMIPSSQVDDLTSPAKRKRTSSPTKNTSDVWSSGHTVSHPPVQQQIHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQVALTRVPNVAQRGIRPACPGQPMANGPFPAGPIPCSTARTLSSTDTILIGNNHITESGSNGNVPYLQQNALSLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQASGTGIQNQNGHPATPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSAVPETSRHSGETPNSTAGVEGLPNHVHQVTADAVSSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTENSIASSPSSAISTATPSPKSTEPTTTNSVTSLNSPHSGHTVNGEGLEDSQSPVKADPPPISHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPPPPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHVVEVRTQLLQPADENWDPTGTKKIWRCESSRSHTTIAKYAQYQASSFQESLREENEKKSHHKDHSDNESTSSDNSGRRRRGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPESYWGVMNDFCEKNNMNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIVWHGRAKDEPAHYCSICEVEVFDLLFVTSESNSRKTYVVHCQDCARKISTNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS", "length": 1453, "header": "tr|V9GWR3-1|V9GWR3_CHICK Isoform 1 of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Gallus gallus OX=9031 GN=KDM6A PE=3 SV=1 CANONICAL=V9GWR3-1" }, "locus": { "chromosome": "1", "start_pos": 111059206, "end_pos": 110911946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027329.1", "url": "https://www.ensembl.org/id/ENSGALT00010027329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015583.1", "url": "https://www.ensembl.org/id/ENSGALP00010015583.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 581, "start_aa": "Thr", "end_pos": 581, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr581", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 738, "start_aa": "Thr", "end_pos": 738, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr738", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 992, "start_aa": "Thr", "end_pos": 992, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr992", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "histone H3K27me2/H3K27me3 demethylase activity", "id": "GO:0071558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "V9GWR3", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60224", "name": "", "equation": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "V9GWR3-1" ], "evidence": [ { "id": "60224", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60224" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "V9GWR3", "gene_name": "KDM6A", "activity": [ { "ec_number": "1.14.11.68", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "V9GWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ] }, { "ec_number": "1.14.11.68", "activity": "", "evidence": [ { "id": "V9GWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "V9GWR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWR3" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjC", "eco_id": "ECO_0000259", "start_pos": 1147, "end_pos": 1310, "start_aa": "Lys", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.68", "ec_name": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "1.14.11.68", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.68" }, { "id": "1.14.11.68", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.68" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 581, 738, 992 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1115, "end_pos": 1117 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 691, "end_pos": 693 }, { "start_pos": 776, "end_pos": 778 }, { "start_pos": 792, "end_pos": 794 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4F4-1", "uniprot_ac": "F1P4F4", "uniprot_id": "F1P4F4_CHICK", "mass": { "chemical_mass": 32172.0, "monoisotopic_mass": 32172.0 }, "refseq": { "ac": "NP_001006375", "name": "translocon-associated protein subunit alpha precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" }, "gene_names": [ { "name": "SSR1", "type": "recommended", "evidence": [ { "id": "F1P4F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F4" } ] }, { "name": "SSR1", "type": "synonym", "evidence": [ { "id": "NP_001006375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" } ] } ], "protein_names": [ { "name": "Translocon-associated protein subunit alpha", "type": "recommended", "evidence": [ { "id": "F1P4F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#names_and_taxonomy" } ] }, { "name": "Signal sequence receptor subunit alpha", "type": "synonym", "evidence": [ { "id": "F1P4F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#names_and_taxonomy" } ] }, { "name": "TRAP-alpha", "type": "synonym", "evidence": [ { "id": "F1P4F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#names_and_taxonomy" } ] }, { "name": "signal sequence receptor, alpha (translocon-associated protein alpha)", "type": "synonym", "evidence": [ { "id": "NP_001006375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" } ] }, { "name": "translocon-associated protein subunit alpha precursor", "type": "synonym", "evidence": [ { "id": "NP_001006375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" } ] }, { "name": "translocon-associated protein subunit alpha", "type": "synonym", "evidence": [ { "id": "NP_001006375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000158.1, AJ719521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000040.1. On Sep 23, 2021 this sequence version replaced NP_001006375.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375" } ] }, { "annotation": "TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y4P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4P5#function" }, { "database": "UniProtKB", "id": "RU368074", "url": "https://www.uniprot.org/uniprotkb/RU368074#function" }, { "database": "UniProtKB", "id": "ARBA00025620", "url": "https://www.uniprot.org/uniprotkb/ARBA00025620#function" }, { "database": "UniProtKB", "id": "A0A8V0Y4M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4M8#function" }, { "database": "UniProtKB", "id": "A0A8V0Y693", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y693#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K0#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K4#function" }, { "database": "UniProtKB", "id": "F1P4F4", "url": "https://www.uniprot.org/uniprotkb/F1P4F4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4F4", "url": "https://www.uniprot.org/uniprotkb/F1P4F4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSR1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4", "locus": { "chromosome": "2", "start_pos": 64380699, "end_pos": 64348364, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010270", "url": "https://www.ensembl.org/id/ENSGALG00010010270" } ] } } ], "crossref": [ { "id": "F1P4F4", "url": "https://alphafold.ebi.ac.uk/entry/F1P4F4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012798", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012798", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420871", "url": "https://www.ncbi.nlm.nih.gov/gene/420871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420871", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y4M8", "url": "https://www.orthodb.org/?gene=A0A8V0Y4M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4P5", "url": "https://www.orthodb.org/?gene=A0A8V0Y4P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y693", "url": "https://www.orthodb.org/?gene=A0A8V0Y693", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8K0", "url": "https://www.orthodb.org/?gene=A0A8V0Y8K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8K4", "url": "https://www.orthodb.org/?gene=A0A8V0Y8K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4F4", "url": "https://www.orthodb.org/?gene=F1P4F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12924:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12924:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006375", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y693", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y693", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y693-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y693-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4F4", "url": "https://www.uniprot.org/uniprotkb/F1P4F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4F4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSVPRLLLLALLVFPAALLLRGSGTGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE", "length": 288, "header": "tr|F1P4F4-1|F1P4F4_CHICK Isoform 1 of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4M8-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#A0A8V0Y4M8-1", "sequence": { "sequence": "MRSVPRLLLLALLVFPAALLLRGSGTGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLLNILISDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE", "length": 265, "header": "tr|A0A8V0Y4M8-1|F1P4F4_CHICK Computationally mapped isoform of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64367900, "end_pos": 64358996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024513.1", "url": "https://www.ensembl.org/id/ENSGALT00010024513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013910.1", "url": "https://www.ensembl.org/id/ENSGALP00010013910.1" } ] } }, { "isoform_ac": "A0A8V0Y4P5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#A0A8V0Y4P5-1", "sequence": { "sequence": "MRSVPRLLLLALLVFPAALLLRGSGTGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQIMQSRRDKASPRRLPRKRAQKRSVGSDELIPPGVKETRVLSSSILPWPSELDVQLR", "length": 321, "header": "tr|A0A8V0Y4P5-1|F1P4F4_CHICK Computationally mapped isoform of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64379695, "end_pos": 64358996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024550.1", "url": "https://www.ensembl.org/id/ENSGALT00010024550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013930.1", "url": "https://www.ensembl.org/id/ENSGALP00010013930.1" } ] } }, { "isoform_ac": "A0A8V0Y693-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#A0A8V0Y693-1", "sequence": { "sequence": "GLKRDITPKLSWQLGCPLHTASVFCWLRRYWKAFVHLVSIGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE", "length": 302, "header": "tr|A0A8V0Y693-1|F1P4F4_CHICK Computationally mapped isoform of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64367900, "end_pos": 64360332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024526.1", "url": "https://www.ensembl.org/id/ENSGALT00010024526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013913.1", "url": "https://www.ensembl.org/id/ENSGALP00010013913.1" } ] } }, { "isoform_ac": "A0A8V0Y8K0-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#A0A8V0Y8K0-1", "sequence": { "sequence": "RRKLQTLWQTEEHRTEGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE", "length": 278, "header": "tr|A0A8V0Y8K0-1|F1P4F4_CHICK Computationally mapped isoform of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64367900, "end_pos": 64355210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024535.1", "url": "https://www.ensembl.org/id/ENSGALT00010024535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013919.1", "url": "https://www.ensembl.org/id/ENSGALP00010013919.1" } ] } }, { "isoform_ac": "A0A8V0Y8K4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#A0A8V0Y8K4-1", "sequence": { "sequence": "MRSVPRLLLLALLVFPAALLLRGSGTGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQIKRLIPPGVKETRVLSSSILPWPSELDVQLR", "length": 296, "header": "tr|A0A8V0Y8K4-1|F1P4F4_CHICK Computationally mapped isoform of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64379695, "end_pos": 64358996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024543.1", "url": "https://www.ensembl.org/id/ENSGALT00010024543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013924.1", "url": "https://www.ensembl.org/id/ENSGALP00010013924.1" } ] } }, { "isoform_ac": "F1P4F4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F4/entry#F1P4F4-1", "sequence": { "sequence": "MRSVPRLLLLALLVFPAALLLRGSGTGSGLLVAAQDATEDEETVEDTVVEDEDDEAEVEEDEPTDLTEEKEEEDLSGEPKASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYRDANGNMFQDAVFNQTVTIIEKEDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPVQKVEMGTSNQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE", "length": 288, "header": "tr|F1P4F4-1|F1P4F4_CHICK Isoform 1 of Translocon-associated protein subunit alpha OS=Gallus gallus OX=9031 GN=SSR1 PE=1 SV=1 CANONICAL=F1P4F4-1" }, "locus": { "chromosome": "2", "start_pos": 64367900, "end_pos": 64358996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024529.1", "url": "https://www.ensembl.org/id/ENSGALT00010024529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013915.1", "url": "https://www.ensembl.org/id/ENSGALP00010013915.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420871", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P4F4", "url": "https://www.uniprot.org/uniprotkb/F1P4F4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1P4F4", "url": "https://www.uniprot.org/uniprotkb/F1P4F4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F2Z4K6-1", "uniprot_ac": "F2Z4K6", "uniprot_id": "F2Z4K6_CHICK", "mass": { "chemical_mass": 17258.0, "monoisotopic_mass": 17258.0 }, "refseq": { "ac": "NP_001264027", "name": "60S ribosomal protein L26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" }, "gene_names": [ { "name": "RPL26L1", "type": "recommended", "evidence": [ { "id": "F2Z4K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ] }, { "name": "RPL26L1", "type": "synonym", "evidence": [ { "id": "NP_001264027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" } ] }, { "name": "RPL26", "type": "synonym", "evidence": [ { "id": "NP_001264027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" } ] } ], "protein_names": [ { "name": "60S ribosomal protein L26", "type": "synonym", "evidence": [ { "id": "NP_001264027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" } ] }, { "name": "KRAB-A domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001264027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" } ] }, { "name": "Ribosomal protein L26 like 1", "type": "synonym", "evidence": [ { "id": "F2Z4K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX930904.2, BU470850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On or before Mar 10, 2013 this sequence version replaced XP_414531.2, XP_001231499.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL26L1", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6", "locus": { "chromosome": "13", "start_pos": 8754809, "end_pos": 8750453, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009170", "url": "https://www.ensembl.org/id/ENSGALG00010009170" } ] } } ], "crossref": [ { "id": "F2Z4K6", "url": "https://alphafold.ebi.ac.uk/entry/F2Z4K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002868", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002868", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06089", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06089", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396400", "url": "https://www.ncbi.nlm.nih.gov/gene/396400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR005756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396400", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRIMRGD", "url": "https://omabrowser.org/oma/group/VRIMRGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4V6", "url": "https://www.orthodb.org/?gene=A0A8V0Y4V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F2Z4K6", "url": "https://www.orthodb.org/?gene=F2Z4K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264027", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z4K6-1", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145, "header": "tr|F2Z4K6-1|F2Z4K6_CHICK Isoform 1 of Ribosomal protein L26 like 1 OS=Gallus gallus OX=9031 GN=RPL26L1 PE=1 SV=1 CANONICAL=F2Z4K6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4V6-1", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6/entry#A0A8V0Y4V6-1", "sequence": { "sequence": "MCVDDKCESQVSQTAFLRAAKMKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 166, "header": "tr|A0A8V0Y4V6-1|F2Z4K6_CHICK Computationally mapped isoform of Ribosomal protein L26 like 1 OS=Gallus gallus OX=9031 GN=RPL26L1 PE=1 SV=1 CANONICAL=F2Z4K6-1" }, "locus": { "chromosome": "13", "start_pos": 8754763, "end_pos": 8751437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021901.1", "url": "https://www.ensembl.org/id/ENSGALT00010021901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012537.1", "url": "https://www.ensembl.org/id/ENSGALP00010012537.1" } ] } }, { "isoform_ac": "F2Z4K6-1", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6/entry#F2Z4K6-1", "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145, "header": "tr|F2Z4K6-1|F2Z4K6_CHICK Isoform 1 of Ribosomal protein L26 like 1 OS=Gallus gallus OX=9031 GN=RPL26L1 PE=1 SV=1 CANONICAL=F2Z4K6-1" }, "locus": { "chromosome": "13", "start_pos": 8754763, "end_pos": 8751500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021894.1", "url": "https://www.ensembl.org/id/ENSGALT00010021894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012534.1", "url": "https://www.ensembl.org/id/ENSGALP00010012534.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:396400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396400", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L7Y1-1", "protein_name": "Ribosomal protein L26", "gene_name": "RPL26", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53221-1", "protein_name": "Large ribosomal subunit protein uL24B", "gene_name": "RPL26B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKQSLDVSSDRRKARKAYFTAPSSERRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVITKLHLDKDRKALIQRKGGKLE", "length": 127 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61255-1", "protein_name": "Large ribosomal subunit protein uL24", "gene_name": "Rpl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61257-1", "protein_name": "Large ribosomal subunit protein uL24", "gene_name": "RPL26", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE", "length": 145 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54QM8-1", "protein_name": "Large ribosomal subunit protein uL24", "gene_name": "rpl26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKRNTNVSSSRRKSRKAHFTASSGERRIRMSAALSHDLRTKYNVRSLPIRKDDEVRVVCGDNKNHEGKVVACYRKKYVIHIDKLTVTKTNGNTAQIGVSPSNVILTKLKLDKDRKALLERKNRTVAADKGKVKVSADVN", "length": 139 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VVU2-1", "protein_name": "Ribosomal protein L26, isoform C", "gene_name": "RpL26", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKQNPFVSSSRRKNRKRHFQAPSHIRRRLMSAPLSKELRQKYNVRSMPIRRDDEVQVIRGHFKGNQVGKVVQAYRKKFVVYVEKIQRENANGTNVYVGIHPSKVLIVKLKLDKDRKAILERRGKGRLAALGKDKGKYTEETAAQPMETA", "length": 149 }, "evidence": [ { "id": "F2Z4K6", "url": "https://omabrowser.org/oma/group/F2Z4K6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "large ribosomal subunit", "id": "GO:0015934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015934", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043517", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "cellular response to gamma radiation", "id": "GO:0071480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071480", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:1902167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902167", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "regulation of translation involved in cellular response to UV", "id": "GO:1904803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904803", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F2Z4K6", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F2Z4K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4K6" }, { "id": "SM00739", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KOW", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 76, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1P4C5-1", "uniprot_ac": "F1P4C5", "uniprot_id": "F1P4C5_CHICK", "mass": { "chemical_mass": 81604.0, "monoisotopic_mass": 81604.0 }, "refseq": { "ac": "XP_015139411", "name": "ubiquitin carboxyl-terminal hydrolase 44 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139411" }, "gene_names": [ { "name": "USP44", "type": "recommended", "evidence": [ { "id": "F1P4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ] }, { "name": "USP44", "type": "synonym", "evidence": [ { "id": "XP_015139411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139411" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase", "type": "recommended", "evidence": [ { "id": "F1P4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4C5/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1P4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4C5/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 44 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139411" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139411" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP44", "url": "https://www.uniprot.org/uniprotkb/F1P4C5", "locus": { "chromosome": "1", "start_pos": 45604444, "end_pos": 45621758, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011819", "url": "https://www.ensembl.org/id/ENSGALG00010011819" } ] } } ], "crossref": [ { "id": "F1P4C5", "url": "https://alphafold.ebi.ac.uk/entry/F1P4C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011400", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011400", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417913", "url": "https://www.ncbi.nlm.nih.gov/gene/417913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417913", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417913", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYQCNGK", "url": "https://omabrowser.org/oma/group/RYQCNGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6B4", "url": "https://www.orthodb.org/?gene=A0A8V0Y6B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4C5", "url": "https://www.orthodb.org/?gene=F1P4C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139411", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4C5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKCKHIGRLRLAQDHSILNPQKWHCVDCNTTESVWACLSCSHVACGRYIEEHALKHFQENGHPVALEVNELYVFCYLCDDYVLNDNATGDIKLLRSTLSAIKSQKYECTTRSGRTLRSMGASDDSYLSHDGAQALLRNQDRMFTALWHRRRAFMGKIFRSWFQLTPSGKKILEEEKRLEEEEERRNKARKRRQERKRQLKEEMEKMPPRKSCRLQNQMRMSSQTASVTQKTSQSTESVSELKETYTSDEVRLKKIGDSPIKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLLIFRECFLKLDLNQTQELLATAASGKTRSSSRRSSVTASTLQANENQEKGRGSSSVRRSNLSSGLSGGASKSRNMELIQPREPSSKHISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKVQQELETTGTRYPALIPAAQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYHCNGKEMASQYPCPLTEMLAKFTETEALEGKIYACDQCNTKRRKFSSKPVILTEAQKQLMVCRLPQVLRLHLKRFRWSGRNHREKIGVHVNFDQILNMEPYCCRESLKSLLPDCFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLNMCTMEEVCKAQAYILFYSQRLSQANGLGKICPSTSESQQHTELADCSVDNSSS", "length": 714, "header": "tr|F1P4C5-1|F1P4C5_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP44 PE=3 SV=2 CANONICAL=F1P4C5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6B4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4C5/entry#A0A8V0Y6B4-1", "sequence": { "sequence": "MDKCKHIGRLRLAQDHSILNPQKWHCVDCNTTESVWACLSCSHVACGRYIEEHALKHFQENGHPVALEVNELYVFCYLCDDYVLNDNATGDIKLLRSTLSAIKSQKYECTTRSGRTLRSMGASDDSYLSHDGAQALLRNQDRMFTALWHRRRAFMGKIFRSWFQLTPSGKKILEEEKRLEEEEERRNKARKRRQERKRQLKEEMEKMPPRKSCRLQNQMRMSSQTASVTQKTSQSTESVSELKETYTSDEVRLKKIGDSPIKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLLIFRECFLKLDLNQTQELLATAASGKTRSSSRRSSVTASTLQANENQEKGRGSSSVRRSNLSSGLSGGASKSRNMELIQPREPSSKHISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKVQQELETTGTRYPALIPAAQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYHCNGKEMASQYPCPLTEMLAKFTETEALEGKIYACDQCNIILTEAQKQLMVCRLPQVLRLHLKRFRWSGRNHREKIGVHVNFDQILNMEPYCCRESLKSLLPDCFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGRNQL", "length": 644, "header": "tr|A0A8V0Y6B4-1|F1P4C5_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP44 PE=3 SV=1 CANONICAL=F1P4C5-1" }, "locus": { "chromosome": "1", "start_pos": 45617781, "end_pos": 45606988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028246.1", "url": "https://www.ensembl.org/id/ENSGALT00010028246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016183.1", "url": "https://www.ensembl.org/id/ENSGALP00010016183.1" } ] } }, { "isoform_ac": "F1P4C5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4C5/entry#F1P4C5-1", "sequence": { "sequence": "MDKCKHIGRLRLAQDHSILNPQKWHCVDCNTTESVWACLSCSHVACGRYIEEHALKHFQENGHPVALEVNELYVFCYLCDDYVLNDNATGDIKLLRSTLSAIKSQKYECTTRSGRTLRSMGASDDSYLSHDGAQALLRNQDRMFTALWHRRRAFMGKIFRSWFQLTPSGKKILEEEKRLEEEEERRNKARKRRQERKRQLKEEMEKMPPRKSCRLQNQMRMSSQTASVTQKTSQSTESVSELKETYTSDEVRLKKIGDSPIKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLLIFRECFLKLDLNQTQELLATAASGKTRSSSRRSSVTASTLQANENQEKGRGSSSVRRSNLSSGLSGGASKSRNMELIQPREPSSKHISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKVQQELETTGTRYPALIPAAQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYHCNGKEMASQYPCPLTEMLAKFTETEALEGKIYACDQCNTKRRKFSSKPVILTEAQKQLMVCRLPQVLRLHLKRFRWSGRNHREKIGVHVNFDQILNMEPYCCRESLKSLLPDCFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLNMCTMEEVCKAQAYILFYSQRLSQANGLGKICPSTSESQQHTELADCSVDNSSS", "length": 714, "header": "tr|F1P4C5-1|F1P4C5_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP44 PE=3 SV=2 CANONICAL=F1P4C5-1" }, "locus": { "chromosome": "1", "start_pos": 45617781, "end_pos": 45606414, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028244.1", "url": "https://www.ensembl.org/id/ENSGALT00010028244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016182.1", "url": "https://www.ensembl.org/id/ENSGALP00010016182.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 268, "start_aa": "Thr", "end_pos": 268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr268", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417913", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417913", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AMI4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP44", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTMDKCKHIGRLQLAHDHSILNPQKWHCVDCNTTESIWACLSCPHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYFCDDYVLNDNATGDLKLLRSTLSAIKSQSYHCTTRSGRVLRSVGTSDDSDFLHDGAQSLLQNEDQMYTALWHRRRILMGKIFRTWFEQSPIGRKRQEDQFQEKIAKREVKKRRQELEYQVEAELESMPPRKSLRLQGLAQSTTVEIVPVQVPLQTSASPVKVVSTSEDVRLKKASDFSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNRWLSVTANDKTRSSYKHLPVTDTVYQMNDCQEKETGSLHSRYPSLSLGLSGGASKSRKMELIQPREPSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHELETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGHNNREKIGVHVGFEEILNMEPYCCRESLKSLRPECFIYDLAAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVAENGHSKLLPPELLSGSQHPSEEADTSSNEILS", "length": 709 }, "evidence": [ { "id": "F1P4C5", "url": "https://omabrowser.org/oma/group/F1P4C5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A942-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTENPPRPRQTRSLLTMDRCKHIEQLQLAQGHSILNPQKWFCMVCNTTESIWACLSCSHVACGQYIQEHALKHFEESSHPVAFEVNDMYVFCYLCNDYVLNDNTAGDLKSLRSTLSAIKGKSYPCVVQSDSVLQPVNAQADSYSLHDSTQSLPGSEDPMCTALWHRRRALMGKTFRTWFEQSPIGRKRQEQTQEKTVAKREVKRRQQELEQQMKAELECTPPRKSLRLQGLSEAATVEILPVQAPPPPPASPAKEKALALPPSEDGKLKRVSDSLIKRRPAVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTDAATAAAHQLNEGQEKEKGFACSRHPGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHTLFQVMWSGEWALVSPFAMLHSVWKLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTKLPALIPTSQRRLIEQVLNVVNNIFHGQLLSQVTCLACNNKSNTIEPFWDLSLEFPERYQCSGKDAASQPCLVTDMLGKFTETEALEGKIYVCDHCNSKRRKFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVVFEETLNMEPYCCSETLNALRPECFIYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMEEVLRAQAYILFYTQRVTENGHSRLLPPELLSNSQQHPSEETDTSSNEVLS", "length": 731 }, "evidence": [ { "id": "F1P4C5", "url": "https://omabrowser.org/oma/group/F1P4C5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BLZ0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP44", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTMDKCQHIGQLRLAQDHPILNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALGHFQESSHPVALEVNEMYVFCYLCDDYVLNDNATGDLKLLRSTLSAIKNQNYHCTTRSGRVLRSMGTSDDSYFLHDGTQSLLQHEDQMYTALWHRRRILMGKIFRTWFEQSPIGRKRQEQFQEKLAKREEKKRRQELLEHQAKAELESMPPRKSLRLQALAQSTTVEIVPVQLQTSALPAKDKVVSTSEDVRLKKASDSSVKQRPTVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVTASDKTRSSYKHPPVTDTVYQMNECQEKEPYSVCFRHPSLSSGLSGGAPTSSKMELIQPREPSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYGQQDAQEFLCELLDKIQHELETTGTRSPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDSKSNTIEPFWDLSLEFPERYQCSGKDSASQPCLVTEMLAKFTETEALEGKIYVCDQCNSKRRRFSSKPVLLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRESLKSLRPECFLYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPEFLSGSQHPSEEAETSSNEILS", "length": 709 }, "evidence": [ { "id": "F1P4C5", "url": "https://omabrowser.org/oma/group/F1P4C5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C2S0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44", "gene_name": "Usp44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRCKHVEQLQLAQGHSILDPQKWYCMVCNTTESIWACLSCSHVACGKYIQEHALKHFQESSHPVAFEVNDMYAFCYLCNDYVLNDNAAGDLKSLRSTLSTIKSKKYPCVVPSDSVLHPVDAQDRVYSLLDGTQSLPGNEDPTCAALWHRRRVLMGKAFRTWFEQSAIGRKGQEPTQERMVAKREAKRRQQQELEQQMKAELESTPPRKSLRLQGSSEEAATIEIVPVRAPPPPPASPAKDKAALPTSEDRTFKKVSDSLIKRRPMVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTEAAAQQMNEGQEKEKGFVCSRHSGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHILFQVMWSGEWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTKLPALIPTSQRRLIEQVLNVVNNIFHGQFLSQVTCLACDNKSDTIESFWDLSLEFPERYQCSGKDAASQPCLVTDMLDKFTETEALEGKIYMCDHCNSKRRKFSSKSVVFTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVVFEETLNMEPYCCRETLNALRPECFLYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMEEVRKAQAYILFYTQRVTENGHSKLLPPELLSNSQHPSKETDASSNEVLS", "length": 711 }, "evidence": [ { "id": "F1P4C5", "url": "https://omabrowser.org/oma/group/F1P4C5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0E7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44", "gene_name": "USP44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPFQEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS", "length": 712 }, "evidence": [ { "id": "F1P4C5", "url": "https://omabrowser.org/oma/group/F1P4C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090266", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "negative regulation of mitotic metaphase/anaphase transition", "id": "GO:0045841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045841", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "regulatory T cell differentiation", "id": "GO:0045066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045066", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1P4C5", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5696958", "name": "USP44 deubiquitinates CDC20", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4C5-1" ], "evidence": [ { "id": "R-GGA-5696958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696958" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1P4C5", "gene_name": "USP44", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "F1P4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "F1P4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4C5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4C5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 714, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4C5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4C5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 268 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 30, "end_pos": 32 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 711, "end_pos": 713 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P3V8-1", "uniprot_ac": "F1P3V8", "uniprot_id": "F1P3V8_CHICK", "mass": { "chemical_mass": 71424.0, "monoisotopic_mass": 71424.0 }, "refseq": { "ac": "NP_001186254", "name": "dnaJ homolog subfamily C member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" }, "gene_names": [ { "name": "DNAJC2", "type": "recommended", "evidence": [ { "id": "F1P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ] }, { "name": "DNAJC2", "type": "synonym", "evidence": [ { "id": "NP_001186254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] }, { "name": "ZRF1", "type": "synonym", "evidence": [ { "id": "NP_001186254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily C member 2", "type": "recommended", "evidence": [ { "id": "F1P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3V8/entry#names_and_taxonomy" } ] }, { "name": "DnaJ (Hsp40) homolog, subfamily C, member 2", "type": "synonym", "evidence": [ { "id": "NP_001186254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] }, { "name": "dnaJ homolog subfamily C member 2", "type": "synonym", "evidence": [ { "id": "NP_001186254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] }, { "name": "zuotin related factor 1", "type": "synonym", "evidence": [ { "id": "NP_001186254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267651.21289.1, SRR13267653.27374.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 4, 2010 this sequence version replaced XP_415961.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC2", "url": "https://www.uniprot.org/uniprotkb/F1P3V8", "locus": { "chromosome": "1", "start_pos": 13174771, "end_pos": 13195120, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009571", "url": "https://www.ensembl.org/id/ENSGALG00010009571" } ] } } ], "crossref": [ { "id": "F1P3V8", "url": "https://alphafold.ebi.ac.uk/entry/F1P3V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008249", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008249", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417717", "url": "https://www.ncbi.nlm.nih.gov/gene/417717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417717", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFWYDFD", "url": "https://omabrowser.org/oma/group/SFWYDFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6K2", "url": "https://www.orthodb.org/?gene=A0A8V0Y6K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3V8", "url": "https://www.orthodb.org/?gene=F1P3V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43999:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43999:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3V8-1", "url": "https://www.uniprot.org/uniprotkb/F1P3V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRGAHEGQLTAVTGALTAASVLCQVEPVGRWFEAFIKRRNINVSASFQELEDEKELSEESGDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGNIRYRATQKQIKAAHKSMVLKHHPDKRKAAGEQIGEGDNDYFTCITKAYEILSDPVKRRAFNSIDPTFDNSVPSKSEAKENFFEVFSPVFERNARWSNKKNVPKLGDVNSSFEEVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRAARALRKKEEMNRIRILVDNAYSCDPRIKKFKEEEKAKKEAEKKAKVEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALVAKKEKEIQKKAIKKERQKLRTTCKNWNYFSDNEADCVKMMEEVEKLCDRLELASLQCLNEALTSTTREGGKAAVVKQIEEINEQIRREKEEAEARMRQATKSSEKSTTGGGGGSKNWPEDDLQLLIKAVNLFPAGTNSRWEVIANYMNLHSTTGIKRTAKDVINKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQMDTAAPSERFEGSPLDSSPWTTEEQKLLEQALKTYPVNTPERWEKIAAAVPGRSKKDCMKRYKELVEMVKAKKAAQEQVMNATKVKK", "length": 619, "header": "tr|F1P3V8-1|F1P3V8_CHICK Isoform 1 of DnaJ homolog subfamily C member 2 OS=Gallus gallus OX=9031 GN=DNAJC2 PE=1 SV=2 CANONICAL=F1P3V8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6K2-1", "url": "https://www.uniprot.org/uniprotkb/F1P3V8/entry#A0A8V0Y6K2-1", "sequence": { "sequence": "MLCSSSARTKKESTHLATCKGCSLWRVCLSAARSQRAGGARPVSDSLIPVYNTDKMRRKKQQELEDEKELSEESGDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGNIRYRATQKQIKAAHKSMVLKHHPDKRKAAGEQIGEGDNDYFTCITKAYEILSDPVKRRAFNSIDPTFDNSVPSKSEAKENFFEVFSPVFERNARWSNKKNVPKLGDVNSSFEEVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRAARALRKKEEMNRIRILVDNAYSCDPRIKKFKEEEKAKKEAEKKAKVEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALVAKKEKEIQKKAIKKERQKLRTTCKNWNYFSDNEADCVKMMEEVEKLCDRLELASLQCLNEALTSTTREGGKAAVVKQIEEINEQIRREKEEAEARMRQATKSSEKSTTGGGGGSKNWPEDDLQLLIKAVNLFPAGTNSRWEVIANYMNLHSTTGIKRTAKDVINKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQMDTAAPSERFEGSPLDSSPWTTEEQKLLEQALKTYPVNTPERWEKIAAAVPGRSKKDCMKRYKELVEMVKAKKAAQEQVMNATKVKK", "length": 632, "header": "tr|A0A8V0Y6K2-1|F1P3V8_CHICK Computationally mapped isoform of DnaJ homolog subfamily C member 2 OS=Gallus gallus OX=9031 GN=DNAJC2 PE=1 SV=1 CANONICAL=F1P3V8-1" }, "locus": { "chromosome": "1", "start_pos": 13194921, "end_pos": 13174845, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022814.1", "url": "https://www.ensembl.org/id/ENSGALT00010022814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013187.1", "url": "https://www.ensembl.org/id/ENSGALP00010013187.1" } ] } }, { "isoform_ac": "F1P3V8-1", "url": "https://www.uniprot.org/uniprotkb/F1P3V8/entry#F1P3V8-1", "sequence": { "sequence": "MLRGAHEGQLTAVTGALTAASVLCQVEPVGRWFEAFIKRRNINVSASFQELEDEKELSEESGDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGNIRYRATQKQIKAAHKSMVLKHHPDKRKAAGEQIGEGDNDYFTCITKAYEILSDPVKRRAFNSIDPTFDNSVPSKSEAKENFFEVFSPVFERNARWSNKKNVPKLGDVNSSFEEVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRAARALRKKEEMNRIRILVDNAYSCDPRIKKFKEEEKAKKEAEKKAKVEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALVAKKEKEIQKKAIKKERQKLRTTCKNWNYFSDNEADCVKMMEEVEKLCDRLELASLQCLNEALTSTTREGGKAAVVKQIEEINEQIRREKEEAEARMRQATKSSEKSTTGGGGGSKNWPEDDLQLLIKAVNLFPAGTNSRWEVIANYMNLHSTTGIKRTAKDVINKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQMDTAAPSERFEGSPLDSSPWTTEEQKLLEQALKTYPVNTPERWEKIAAAVPGRSKKDCMKRYKELVEMVKAKKAAQEQVMNATKVKK", "length": 619, "header": "tr|F1P3V8-1|F1P3V8_CHICK Isoform 1 of DnaJ homolog subfamily C member 2 OS=Gallus gallus OX=9031 GN=DNAJC2 PE=1 SV=2 CANONICAL=F1P3V8-1" }, "locus": { "chromosome": "1", "start_pos": 13191956, "end_pos": 13174845, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022810.1", "url": "https://www.ensembl.org/id/ENSGALT00010022810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013186.1", "url": "https://www.ensembl.org/id/ENSGALP00010013186.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417717", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F4J6A8-1", "protein_name": "DnaJ and Myb-like DNA-binding domain-containing protein", "gene_name": "ATGLSA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPSRRSESAIRLITYSEELVDGKPFFAFSNCLPVKALNREPAGHAFHSAALKLHGCAEEPTDDEGGDKKVGDDKEKEYVPSFNSYANKGKKKSGTQQQDHYALLGLSNLRYLATEDQIRKSYREAALKHHPDKLASLLLLEETEEAKEAKKDEIESRFKAIQEAYEVLMDPTRRRIFDSTDEFDDEVPSDCLPQDFFKVFGPAFKRNARWSVNQRIPDLGDENTPLKDVDKFYNFWYAFKSWREFPDEEEHDLEQADSREERRWMEKENAKKTVKARKEEHARIRTLVDNAYRKDPRIVKRKEEEKAEKQQKKDAKIQAKKKQEEDAAIAAEEEKRRKEEEEKRAAESAQQQKKTKEREKKLLRKERNRLRTLSAPLVAQRLLDISEEDIENLCMSLNTEQLQNLCDKMGNKEGLELAKVIKDGCNSSRNDEAESKEKVSKKTNGGTEPTTRVSQLDSSTQKKQPWSKEEIDMLRKGMIKYPKGTSRRWEVISEYIGTGRSVEEILKATKTVLLQKPDSAKAFDSFLEKRKPSASITSPLSTREELGESLPTMTTTTNAKPSKETVVGKSSSSQSSDNNGEVGGSSDADSWSTVQERALVQALKTFPKETSQRWERVAAAVPGKTMNQCKKKFAELKEIIRNKKTGV", "length": 647 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P54103-1", "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "Dnajc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLPSAAEGQGTAITHALTSASSVCQVEPVGRWFEAFVKRRNRNASTSFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKSWNHFSDNEADRVKMMEEVEKLCDRLELASLQGLNEILASSTREVGKAALEKQIEEVNEQMRREKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVISKAKSLQKLDPHQKDDINKKAFDKFKKEHGVASQADSAAPSERFEGPCIDSTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK", "length": 621 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMH9-1", "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "DNAJC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLLPSAADGQGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKADAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNLCKTWNHFSDSEAERVKMMEEVEKLCDRLELSSLQCLNETLTSSTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNAEKSAGGGGNGSKHWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPCTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRGKK", "length": 621 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54YL9-1", "protein_name": "Myb domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLVVSLSSPTAEEWSNENSREIHYTNGSLGWSECNRSVEPIGEEFELVWSKVKKGDVEIIGLVSATSDDKKSQDSNDDDNIDELKENYKNNHKEWTKTGKDVNHYKIMGLDHLRWRATDNDIKLAYKKMILVVHPDKNQDLGGNDEAFKALVKSNNILSDIKKRRAYDSTDPFDDDIPTADEEGDFFEIYEPVFDSNSRWSNVQPVPKLGDMDTPYDKVVKFYNFWWSFKSWRDFTFEDDHDLDNADSREEKRWMERENEKKRVKQRKIEAARIQDLANLAYKKDPRIQKKLKEEDDKKNAHKNAKNEAKRKAQEEKEAAEKAEKERVEAEEKRKKDEAEEKKRVKAEQTALLKKGKIQFRDICKSFQPPQKIEDVELVIATLDNLQLGELTKEMETKNNVTDKKAVFLVQLNEIQEKQREADRLYQEQRKALLNNKKEAKPERPWTEDELHLLAKAIQKFPPGVTKRWESVASCIPTRSLKDVIAKAKTSQPTQQQSFSKPEAAPSGSDYDKLKAKVGHMEIKSELSSKVDLGQYPVGTTSNGTESTTTATAPSTVDTAKPAAKKETTTTTASVEWTPEEQKLLEEALQKVDKNAEDRWDQIAARLGTKSKKDCVARFKYLATMVKNIQPTK", "length": 634 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6NWJ4-1", "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "dnajc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTEALEGQLTVVYNTVAASVQVQVEPVGRWFEAFLKRRNRNVSASFQELEEEEELSEEEEDEELQLEEYPMLKTLDPKDWKNQDHYAVLGLAHVRYKATQKQIKAAHKAMVLKHHPDKRKAAGEQIVEGDNDYFTCITKAIEILSDPVKRRAFDSVDPTFDNAVPTKAEGKENFFEVFAPVFERNARWSVKKHFPSLGTMESSFEDVDNFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRASRAQRKKEEMNRIRTLVDTAYNADPRIKKFKEEEKARKESEKKAKVEAKKREQEEKERARQQQEEAARLLKEQQEEAARQAAQQAKKEKEAQKKAIKKERQKLRMTCKSQNYFTDNEADSVRMMEEVEKLCDRLELISLQTLNEALSAGNKEQSKAALEKQVQEVNMQLQKEKDAELQAQQAARGSEHSSAAGGQNNRGWSEEDLQLLIKAVNLFPAGTNARWEVIANYMNQHSSSGVRRTAKDVINKAKTLQKLDPHQKDEINRKAFEKFKKEHSAVPPTVDNAMPSERFDAVGADSNAAAWTTEEQKLLEQALKTYPVSTAERWERISEAVPGRSKKDCMKRYKELVEMIKAKKAAQEQVAAKNKK", "length": 618 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TQ20-1", "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "Dnajc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLPSAAEGQGTAITHALTSASAVCQVEPVGRWFEAFVKRRNRNASTSFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKTMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKENFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEGKAKKEAEKRAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKEIQKKAIKKERQKLRNSCKNWNHFSDNEADRVKMMEEVEKLCDRLELASLQCLNEILASSTREVGKAALEKQIEEVNELMRKEKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVAPQADSAAPSERFEGPCIDSIPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK", "length": 621 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99543-1", "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "DNAJC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKTWNHFSDNEAERVKMMEEVEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRAKK", "length": 621 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VP77-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG10565", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSGTVATAVEVQLPLKVVRRKIERVGFAYFAQRRQFLAPGGVERSESDEKLEGVGEEVDISYLKSLDPKEWKDQDHYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEILGTSKPRRSFDSVDPEFDDSLPSQNDIDNDYFGVFNKFFTLNGRWSEKPHVPSFGQVDAKREEVERFYNFWYDFKSWREFSYLDEEDKEKGQDRDERRWIEKENRAARIKRKKEEMSRIRSLVDLAYNNDKRIQRFKQEEKDRKAAAKRAKMDAAQAQKAEADRAIREAALAKEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKDCKYYAKNDKDQLKHMEGTEKICETFNLAELQALNKAMESKGRESFVAALQTAEQKIAAELEEINQTQAKKLASSAATPKGVKEVKKNELWSNENVQLLIKAVNLFPAGTAQRWDVIATFINQHSPDNTVLVNARDVLNKAKALQNTDHSKSSLKTQANDAAFASFEKSKKDVQTCKDITLGEETAQASKENLKQNGVDHKANNQSTKQNGTAPAPANPTAAPAPVPATNGSTGGGAASKTWTKEEQALLEQAIKTYPTTTPDRWDCIAACIPNRSKKDCLRRVKELVELVNSKKEAQAAVK", "length": 646 }, "evidence": [ { "id": "F1P3V8", "url": "https://omabrowser.org/oma/group/F1P3V8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "F1P3V8", "url": "https://www.uniprot.org/uniprotkb/F1P3V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 613, "end_pos": 615 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q98942-1", "uniprot_ac": "Q98942", "uniprot_id": "Q98942_CHICK", "mass": { "chemical_mass": 57478.0, "monoisotopic_mass": 57478.0 }, "refseq": {}, "gene_names": [ { "name": "AMY2A", "type": "recommended", "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ] } ], "protein_names": [ { "name": "Alpha-amylase", "type": "recommended", "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.1", "type": "synonym", "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMY2A", "url": "https://www.uniprot.org/uniprotkb/Q98942", "locus": { "chromosome": "8", "start_pos": 55919, "end_pos": 64787, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011790", "url": "https://www.ensembl.org/id/ENSGALG00010011790" } ] } } ], "crossref": [ { "id": "GH13", "url": "http://www.cazy.org/GH13.html", "database": "CAZy", "categories": [ "Protein Classification" ] }, { "id": "cd11317", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11317", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414140", "url": "https://www.ncbi.nlm.nih.gov/gene/414140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:414140", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRYAYDL", "url": "https://omabrowser.org/oma/group/FRYAYDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB14", "url": "https://www.orthodb.org/?gene=A0A8V0YB14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCH1", "url": "https://www.orthodb.org/?gene=A0A8V0YCH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q98942", "url": "https://www.orthodb.org/?gene=Q98942", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YB14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98942-1", "url": "https://www.uniprot.org/uniprotkb/Q98942-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVLLLLAAVGLCWAQYNPNTQAGRTSIVHLFEWRWADIALECEHYLAPNGFGGVQVSPPNENIVITNPNRPWWERYQPISYKICSRSGNENEFRDMVTRCNNVGVRIYVDAVVNHMCGSMGGTGTHSTCGSYFNTGTRDFPAVPYSAWDFNDGKCHTASGDIENYGDMYQVRDCKLSSLLDLALEKDYVRSTIAAYMNHLIDMGVAGFRIDAAKHMWPGDIRAFLDKLHDLNTQWFSAGTKPFIYQEVIDLGGEPITGSQYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGVDVNDWVGPPSNSDGSTKSVTINADTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFSNWWDNGSNQVAFGRGDRGFIVFNNDDWYMNVDLQTGLPAGTYCDVISGQKEGSACTGKQVYVSSDGKANFQISNSDEDPFVAIHVDAKL", "length": 512, "header": "tr|Q98942-1|Q98942_CHICK Isoform 1 of Alpha-amylase OS=Gallus gallus OX=9031 GN=AMY2A PE=3 SV=1 CANONICAL=Q98942-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB14-1", "url": "https://www.uniprot.org/uniprotkb/Q98942/entry#A0A8V0YB14-1", "sequence": { "sequence": "MHTQEPWGGSEISQRLQCCAARVSPPNENIVITNPNRPWWERYQPISYKICSRSGNENEFRDMVTRCNNVGVRIYVDAVVNHMCGSMGGTGTHSTCGSYFNTGTRDFPAVPYSAWDFNDGKCHTASGDIENYGDMYQVRDCKLSSLLDLALEKDYVRSTIAAYMNHLIDMGVAGFRIDAAKHMWPGDIRAFLDKLHDLNTQWFSAGTKPFIYQEVIDLGGEPITGSQYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGVDVNDWVGPPSNSDGSTKSVTINADTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFSNWWDNGSNQVAFGRGDRGFIVFNNDDWYMNVDLQTGLPAGTYCDVISGQKEGSACTGKQVYVSSDGKANFQISNSDEDPFVAIHVDAKL", "length": 478, "header": "tr|A0A8V0YB14-1|Q98942_CHICK Computationally mapped isoform of Alpha-amylase OS=Gallus gallus OX=9031 GN=AMY2A PE=3 SV=1 CANONICAL=Q98942-1" }, "locus": { "chromosome": "8", "start_pos": 63037, "end_pos": 56050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028196.1", "url": "https://www.ensembl.org/id/ENSGALT00010028196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016162.1", "url": "https://www.ensembl.org/id/ENSGALP00010016162.1" } ] } }, { "isoform_ac": "A0A8V0YCH1-1", "url": "https://www.uniprot.org/uniprotkb/Q98942/entry#A0A8V0YCH1-1", "sequence": { "sequence": "MLQPGLWPVAGLIAQLRSKIFRGEKSDFSVFFLFHPNVRLPCNTVSPPNENIVITNPNRPWWERYQPISYKICSRSGNENEFRDMVTRCNNVGVRIYVDAVVNHMCGSMGGTGTHSTCGSYFNTGTRDFPAVPYSAWDFNDGKCHTASGDIENYGDMYQVRDCKLSSLLDLALEKDYVRSTIAAYMNHLIDMGVAGFRIDAAKHMWPGDIRAFLDKLHDLNTQWFSAGTKPFIYQEVIDLGGEPITGSQYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGVDVNDWVGPPSNSDGSTKSVTINADTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFSNWWDNGSNQVAFGRGDRGFIVFNNDDWYMNVDLQTGLPAGTYCDVISGQKEGSACTGKQVYVSSDGKANFQISNSDEDPFVAIHVDAKL", "length": 500, "header": "tr|A0A8V0YCH1-1|Q98942_CHICK Computationally mapped isoform of Alpha-amylase OS=Gallus gallus OX=9031 GN=AMY2A PE=3 SV=1 CANONICAL=Q98942-1" }, "locus": { "chromosome": "8", "start_pos": 64759, "end_pos": 56050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028204.1", "url": "https://www.ensembl.org/id/ENSGALT00010028204.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016165.1", "url": "https://www.ensembl.org/id/ENSGALP00010016165.1" } ] } }, { "isoform_ac": "Q98942-1", "url": "https://www.uniprot.org/uniprotkb/Q98942/entry#Q98942-1", "sequence": { "sequence": "MQVLLLLAAVGLCWAQYNPNTQAGRTSIVHLFEWRWADIALECEHYLAPNGFGGVQVSPPNENIVITNPNRPWWERYQPISYKICSRSGNENEFRDMVTRCNNVGVRIYVDAVVNHMCGSMGGTGTHSTCGSYFNTGTRDFPAVPYSAWDFNDGKCHTASGDIENYGDMYQVRDCKLSSLLDLALEKDYVRSTIAAYMNHLIDMGVAGFRIDAAKHMWPGDIRAFLDKLHDLNTQWFSAGTKPFIYQEVIDLGGEPITGSQYFGNGRVTEFKYGAKLGTVIRKWNGEKMAYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGVDVNDWVGPPSNSDGSTKSVTINADTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFSNWWDNGSNQVAFGRGDRGFIVFNNDDWYMNVDLQTGLPAGTYCDVISGQKEGSACTGKQVYVSSDGKANFQISNSDEDPFVAIHVDAKL", "length": 512, "header": "tr|Q98942-1|Q98942_CHICK Isoform 1 of Alpha-amylase OS=Gallus gallus OX=9031 GN=AMY2A PE=3 SV=1 CANONICAL=Q98942-1" }, "locus": { "chromosome": "8", "start_pos": 60326, "end_pos": 56050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028191.1", "url": "https://www.ensembl.org/id/ENSGALT00010028191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016159.1", "url": "https://www.ensembl.org/id/ENSGALP00010016159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:414140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414140", "resource": "KEGG Pathway" }, { "id": "R-GGA-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MP21-1", "protein_name": "Alpha-amylase", "gene_name": "LOC539383", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFFLLLSAIGFCWAQYDPHVKSGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPSENAVITDPSRPWWERYQPVSYKLCTRSGNENEFKDMVTRCNNVGVRIYVDAVINHMTGSGVSAGTGSTCGSYFNPGSEDFPAVPYSGWDFNDGKCKTGSGDIESYNDAYQVRDCRLVSLLDLALEKDYVRSTIANYLNHLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTKWFPSGSKPFIYQEVIDLGGEAITSSEYFGNGRVTEFKYGAKLGTVIRKWSGEKMAYLKNWGEGWGFMPSNRALVFVDNHDNQRGHGAGGASILTFWDARLYKMGVGFMLAHPYGFTRVMSSYRWTRHFVNGKDVNDWMGPPNKNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVMFRNVVDGQPFTNWWDNGSNQVAFGRGNKGFIVFNNDDSTLSATLQTGLPAGTYCDVISGDKSGNSCTGIQISVSSDGKAHFSISNSAEDPFIAIHADSKL", "length": 511 }, "evidence": [ { "id": "Q98942", "url": "https://omabrowser.org/oma/group/Q98942/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S574-1", "protein_name": "Alpha-amylase", "gene_name": "AMY2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWDNGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL", "length": 511 }, "evidence": [ { "id": "Q98942", "url": "https://omabrowser.org/oma/group/Q98942/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00687-1", "protein_name": "Alpha-amylase 1", "gene_name": "Amy1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVVHSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPPNNNGKTKEVSINPDSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSETLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI", "length": 511 }, "evidence": [ { "id": "Q98942", "url": "https://omabrowser.org/oma/group/Q98942/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19961-1", "protein_name": "Alpha-amylase 2B", "gene_name": "AMY2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMSGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLVGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "length": 511 }, "evidence": [ { "id": "Q98942", "url": "https://omabrowser.org/oma/group/Q98942/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ], "pmid": "" }, { "name": "alpha-amylase activity", "id": "GO:0004556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004556", "evidence": [ { "database": "UniProtKB", "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q98942", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-188979", "name": "Digestion of linear starch (amylose) by extracellular amylase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-189075" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZV81-1", "Q98942-1" ], "evidence": [ { "id": "R-GGA-188979", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-188979" } ] }, { "id": "R-GGA-191114", "name": "Digestion of branched starch (amylopectin) by extracellular amylase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-189071" ], "output_participant_list": [ "R-ALL-189108" ], "enzyme_list": [ "A0A8V0ZV81-1", "Q98942-1" ], "evidence": [ { "id": "R-GGA-191114", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191114" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-189071", "participant_name": "starch (amylopectin) [extracellular region]", "crossref": [ { "id": "28057", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-189075", "participant_name": "starch (amylose) [extracellular region]", "crossref": [ { "id": "28102", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-189108", "participant_name": "limit dextrins [extracellular region]", "crossref": [ { "id": "28912", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZV81", "gene_name": "AMY1A", "activity": [ { "ec_number": "3.2.1.1", "activity": "Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.", "evidence": [ { "id": "A0A8V0ZV81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV81" } ] }, { "ec_number": "3.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZV81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV81" } ] } ] }, { "uniprot_ac": "Q98942", "gene_name": "AMY2A", "activity": [ { "ec_number": "3.2.1.1", "activity": "Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.", "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ] }, { "ec_number": "3.2.1.1", "activity": "", "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942" }, { "id": "SM00632", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00632" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-amylase C-terminal", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 511, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q98942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98942" }, { "id": "SM00642", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00642" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolase family 13 catalytic", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 414, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.1", "ec_name": "Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.", "evidence": [ { "id": "3.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q98TF5-1", "uniprot_ac": "Q98TF5", "uniprot_id": "RL39_CHICK", "mass": { "chemical_mass": 6379.0, "monoisotopic_mass": 6379.0 }, "refseq": { "ac": "NP_989603", "name": "large ribosomal subunit protein eL39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" }, "gene_names": [ { "name": "RPL39L", "type": "recommended", "evidence": [ { "id": "Q98TF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF5" } ] }, { "name": "RPL39", "type": "recommended", "evidence": [ { "id": "Q98TF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF5" } ] }, { "name": "RPL39L", "type": "synonym", "evidence": [ { "id": "NP_989603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" } ] }, { "name": "RPL39", "type": "synonym", "evidence": [ { "id": "NP_989603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL39", "type": "recommended", "evidence": [ { "id": "Q98TF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF5/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L39", "type": "synonym", "evidence": [ { "id": "NP_989603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" }, { "id": "Q98TF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF5/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL39", "type": "synonym", "evidence": [ { "id": "NP_989603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000415.1, CD733961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989603" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98TF5", "url": "https://www.uniprot.org/uniprotkb/Q98TF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL39", "url": "https://www.uniprot.org/uniprotkb/Q98TF5", "locus": {} } ], "crossref": [ { "id": "Q98TF5", "url": "https://alphafold.ebi.ac.uk/entry/Q98TF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008620", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "374132", "url": "https://www.ncbi.nlm.nih.gov/gene/374132", 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"url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#names_and_taxonomy" } ] }, { "name": "Alpha-2,8-sialyltransferase 8D", "type": "synonym", "evidence": [ { "id": "R4GHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#names_and_taxonomy" } ] }, { "name": "CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase", "type": "synonym", "evidence": [ { "id": "NP_989614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989614" } ] }, { "name": "Polysialyltransferase-1", "type": "synonym", "evidence": [ { "id": "R4GHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase 8D", "type": "synonym", "evidence": [ { "id": "R4GHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase St8Sia IV", "type": "synonym", "evidence": [ { "id": "R4GHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#names_and_taxonomy" } ] }, { "name": "sialyltransferase 8D (alpha-2, 8-polysialyltransferase)", "type": "synonym", "evidence": [ { "id": "NP_989614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989614" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.24746.1, AF008194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1. On Nov 20, 2021 this sequence version replaced NP_989614.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989614" } ] }, { "annotation": "Catalyzes the transfer of a sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an N-linked glycan protein acceptor through alpha-2,8-linkages. Therefore, participates in polysialic acid synthesis on various sialylated N-acetyllactosaminyl oligosaccharides, including NCAM1 N-glycans, FETUB N-glycans and AHSG. It is noteworthy that alpha-2,3-linked sialic acid is apparently a better acceptor than alpha-2,6-linked sialic acid.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF98#function" }, { "database": "UniProtKB", "id": "ARBA00046001", "url": "https://www.uniprot.org/uniprotkb/ARBA00046001#function" }, { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST8SIA4", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6", "locus": { "chromosome": "Z", "start_pos": 51374619, "end_pos": 51317308, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011935", "url": "https://www.ensembl.org/id/ENSGALG00010011935" } ] } } ], "crossref": [ { "id": "R4GHQ6", "url": "https://alphafold.ebi.ac.uk/entry/R4GHQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026192", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23988", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23988", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374155", "url": "https://www.ncbi.nlm.nih.gov/gene/374155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374155", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAAEGWK", "url": "https://omabrowser.org/oma/group/HAAEGWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF98", "url": "https://www.orthodb.org/?gene=A0A8V0YF98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GHQ6", "url": "https://www.orthodb.org/?gene=R4GHQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11987:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11987:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "77367", "url": "https://www.rhea-db.org/rhea/77367", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YF98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHQ6-1", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSVRKRWTVCTISLLLIFYKTKEIARTEERQEAPLAGDGELSLSRSMINSSDKIIRKGGSAIFQHSVEGWKINSTLVLEIRKSILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDTHDFVIRCNLAPVVEFAADVGNKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVHIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLHGKPVKYHYYDDLKYRYFSNASPHRMPLEFKTLYVLHNRGALKLTTGKCVQQ", "length": 359, "header": "tr|R4GHQ6-1|R4GHQ6_CHICK Isoform 1 of CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase OS=Gallus gallus OX=9031 GN=ST8SIA4 PE=3 SV=1 CANONICAL=R4GHQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF98-1", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#A0A8V0YF98-1", "sequence": { "sequence": "MRSVRKRWTVCTISLLLIFYKTKEIARTEERQEAPLAGDGELSLSRSMINSSDKIIRKGGSAIFQHSVEGWKINSTLVLEIRALCHGTDIKLLLLLTRIKTETPIKSILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDTHDFVIRCNLAPVVEFAADVGNKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVHIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLHGKPVKYHYYDDLKYRYFSNASPHRMPLEFKTLYVLHNRGALKLTTGKCVQQ", "length": 382, "header": "tr|A0A8V0YF98-1|R4GHQ6_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase OS=Gallus gallus OX=9031 GN=ST8SIA4 PE=3 SV=1 CANONICAL=R4GHQ6-1" }, "locus": { "chromosome": "Z", "start_pos": 51370807, "end_pos": 51317315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028558.1", "url": "https://www.ensembl.org/id/ENSGALT00010028558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016396.1", "url": "https://www.ensembl.org/id/ENSGALP00010016396.1" } ] } }, { "isoform_ac": "R4GHQ6-1", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6/entry#R4GHQ6-1", "sequence": { "sequence": "MRSVRKRWTVCTISLLLIFYKTKEIARTEERQEAPLAGDGELSLSRSMINSSDKIIRKGGSAIFQHSVEGWKINSTLVLEIRKSILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDTHDFVIRCNLAPVVEFAADVGNKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVHIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLHGKPVKYHYYDDLKYRYFSNASPHRMPLEFKTLYVLHNRGALKLTTGKCVQQ", "length": 359, "header": "tr|R4GHQ6-1|R4GHQ6_CHICK Isoform 1 of CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase OS=Gallus gallus OX=9031 GN=ST8SIA4 PE=3 SV=1 CANONICAL=R4GHQ6-1" }, "locus": { "chromosome": "Z", "start_pos": 51370807, "end_pos": 51317315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028560.1", "url": "https://www.ensembl.org/id/ENSGALT00010028560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016398.1", "url": "https://www.ensembl.org/id/ENSGALP00010016398.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374155", "resource": "KEGG Pathway" }, { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TRC7-1", "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase", "gene_name": "ST8SIA4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSIRKRWTICTISLLLIFYKTKEMARTEEHQETQLIGDGELCLSRSLVNSSDKIIRKAGSSIFQHSVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCIKQ", "length": 359 }, "evidence": [ { "id": "R4GHQ6", "url": "https://omabrowser.org/oma/group/R4GHQ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A1KQY6-1", "protein_name": "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4", "gene_name": "St8sia4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHKVSHLKRNPSPREAAQSDPSPASANCAAGRWAALENRESSTAERPSDLILGSRLHAPFANFRFLPLDYFPKTEPLYQEKVPELGQPGLSRAPKMRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNNSDKITRKAGSTIFQHSVQGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCMKQ", "length": 454 }, "evidence": [ { "id": "R4GHQ6", "url": "https://omabrowser.org/oma/group/R4GHQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64690-1", "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase", "gene_name": "ST8SIA4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNSSDKIIRKAGSTIFQHSVQGWRINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDRAKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCMKQ", "length": 359 }, "evidence": [ { "id": "R4GHQ6", "url": "https://omabrowser.org/oma/group/R4GHQ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q64692-1", "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase", "gene_name": "St8sia4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNSSDKIIRKAGSTIFQHSVQGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHNLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLQVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCMKQ", "length": 359 }, "evidence": [ { "id": "R4GHQ6", "url": "https://omabrowser.org/oma/group/R4GHQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92187-1", "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase", "gene_name": "ST8SIA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ", "length": 359 }, "evidence": [ { "id": "R4GHQ6", "url": "https://omabrowser.org/oma/group/R4GHQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity", "id": "GO:0003828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003828", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "sialylation", "id": "GO:0097503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097503", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "R4GHQ6", "url": "https://www.uniprot.org/uniprotkb/R4GHQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "77367", "name": "", "equation": "[N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + CMP-N-acetyl-beta-neuraminate = [N-acetyl-alpha-D-neuraminosyl-(2->8)](n+1) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "77367", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/77367" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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28416.0, "monoisotopic_mass": 28416.0 }, "refseq": {}, "gene_names": [ { "name": "MARCHF3", "type": "recommended", "evidence": [ { "id": "R4GIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "R4GIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "R4GIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MARCHF3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3", "locus": { "chromosome": "Z", "start_pos": 57051536, "end_pos": 57077679, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012745", "url": "https://www.ensembl.org/id/ENSGALG00010012745" } ] } } ], "crossref": [ { "id": "R4GIT3", "url": "https://alphafold.ebi.ac.uk/entry/R4GIT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028673", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768965", "url": "https://www.ncbi.nlm.nih.gov/gene/768965", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768965", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768965", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNDQPIC", "url": "https://omabrowser.org/oma/group/FNDQPIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN5", "url": "https://www.orthodb.org/?gene=A0A8V0YFN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP4", "url": "https://www.orthodb.org/?gene=A0A8V0YGP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GIT3", "url": "https://www.orthodb.org/?gene=R4GIT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46065:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46065:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIT3-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNGRRNPPPAAPPLPAAPRRKSPPRGVPAGPGGGRPRYVMQVAAKDGQLLSSVVRTLATQSSPFNDRPMCRICHEGSSQEDLLSPCECMGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATVSGWLCLRGAVDHLHFSSRLEAVGLIALTIALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSTNIPSNQQSLLGLPSVKRNSKETIV", "length": 253, "header": "tr|R4GIT3-1|R4GIT3_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF3 PE=4 SV=1 CANONICAL=R4GIT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFN5-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT3/entry#A0A8V0YFN5-1", "sequence": { "sequence": "MSCRWRPRTGSCCPPWCGPSPRRGEAAPSSLMTLSPASAVCLFFSPFSLPQKRHCNSPFNDRPMCRICHEGSSQEDLLSPCECMGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATVSGWLCLRGAVDHLHFSSRLEAVGLIALTIALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSTNIPSNQQSLLGLPSVKRNSKETIV", "length": 247, "header": "tr|A0A8V0YFN5-1|R4GIT3_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF3 PE=4 SV=1 CANONICAL=R4GIT3-1" }, "locus": { "chromosome": "Z", "start_pos": 57077323, "end_pos": 57051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030510.1", "url": "https://www.ensembl.org/id/ENSGALT00010030510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017693.1", "url": "https://www.ensembl.org/id/ENSGALP00010017693.1" } ] } }, { "isoform_ac": "A0A8V0YGP4-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT3/entry#A0A8V0YGP4-1", "sequence": { "sequence": "MLRENVGEMAAGGKCCGHCLPRLLLPTLGQQVGDCPEKRSPFNDRPMCRICHEGSSQEDLLSPCECMGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATVSGWLCLRGAVDHLHFSSRLEAVGLIALTIALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSTNIPSNQQSLLGLPSVKRNSKETIV", "length": 230, "header": "tr|A0A8V0YGP4-1|R4GIT3_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF3 PE=4 SV=1 CANONICAL=R4GIT3-1" }, "locus": { "chromosome": "Z", "start_pos": 57076687, "end_pos": 57051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030508.1", "url": "https://www.ensembl.org/id/ENSGALT00010030508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017691.1", "url": "https://www.ensembl.org/id/ENSGALP00010017691.1" } ] } }, { "isoform_ac": "R4GIT3-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT3/entry#R4GIT3-1", "sequence": { "sequence": "MTNGRRNPPPAAPPLPAAPRRKSPPRGVPAGPGGGRPRYVMQVAAKDGQLLSSVVRTLATQSSPFNDRPMCRICHEGSSQEDLLSPCECMGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATVSGWLCLRGAVDHLHFSSRLEAVGLIALTIALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSTNIPSNQQSLLGLPSVKRNSKETIV", "length": 253, "header": "tr|R4GIT3-1|R4GIT3_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF3 PE=4 SV=1 CANONICAL=R4GIT3-1" }, "locus": { "chromosome": "Z", "start_pos": 57077438, "end_pos": 57051832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030515.1", "url": "https://www.ensembl.org/id/ENSGALT00010030515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017697.1", "url": "https://www.ensembl.org/id/ENSGALP00010017697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:768965", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768965", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0JN69-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF3", "gene_name": "MARCHF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTSRCSHLPEVLPDCTGSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNIPSNQQSLLGLHSAKRNSKETIV", "length": 253 }, "evidence": [ { "id": "R4GIT3", "url": "https://omabrowser.org/oma/group/R4GIT3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RKL9-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF3", "gene_name": "MARCHF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVSVPSNQQSLLGLHSAKRNSKETIV", "length": 253 }, "evidence": [ { "id": "R4GIT3", "url": "https://omabrowser.org/oma/group/R4GIT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XIE5-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF3", "gene_name": "Marchf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNIPSNQQSLLGLHSVKRNSKETIV", "length": 253 }, "evidence": [ { "id": "R4GIT3", "url": "https://omabrowser.org/oma/group/R4GIT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UD3-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF3", "gene_name": "MARCHF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNVPSNQPSLLGLHSVKRNSKETVV", "length": 253 }, "evidence": [ { "id": "R4GIT3", "url": "https://omabrowser.org/oma/group/R4GIT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BRX9-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF3", "gene_name": "Marchf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLRRYGHQSKPFWNQSSRS", "length": 218 }, "evidence": [ { "id": "R4GIT3", "url": "https://omabrowser.org/oma/group/R4GIT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "R4GIT3", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GIT3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 253, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GIT3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GIT3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GIT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT3" }, { "id": "PS51292", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-CH-type", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 123, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P541-1", "uniprot_ac": "F1P541", "uniprot_id": "F1P541_CHICK", "mass": { "chemical_mass": 37833.0, "monoisotopic_mass": 37833.0 }, "refseq": { "ac": "NP_001292544", "name": "ubiquitin carboxyl-terminal hydrolase isozyme L5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544" }, "gene_names": [ { "name": "UCHL5", "type": "recommended", "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ] }, { "name": "UCHL5", "type": "synonym", "evidence": [ { "id": "NP_001292544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase", "type": "recommended", "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase L5", "type": "synonym", "evidence": [ { "id": "NP_001292544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase isozyme L5", "type": "synonym", "evidence": [ { "id": "NP_001292544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01106339.1, HAEL01000981.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Sep 23, 2021 this sequence version replaced NP_001292544.1. Transcript Variant: This variant (1) represents the longer transcript and is the protein-coding transcript.", "evidence": [ { "database": "RefSeq", "id": "NP_001292544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544" } ] }, { "annotation": "Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGG7#function" }, { "database": "UniProtKB", "id": "ARBA00054164", "url": "https://www.uniprot.org/uniprotkb/ARBA00054164#function" }, { "database": "UniProtKB", "id": "A0A8V0YGH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH7#function" }, { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UCHL5", "url": "https://www.uniprot.org/uniprotkb/F1P541", "locus": { "chromosome": "8", "start_pos": 3532084, "end_pos": 3519297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012693", "url": "https://www.ensembl.org/id/ENSGALG00010012693" } ] } } ], "crossref": [ { "id": "F1P541", "url": "https://alphafold.ebi.ac.uk/entry/F1P541", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002524", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002524", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424359", "url": "https://www.ncbi.nlm.nih.gov/gene/424359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424359", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIQYEIQ", "url": "https://omabrowser.org/oma/group/YIQYEIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGG7", "url": "https://www.orthodb.org/?gene=A0A8V0YGG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH7", "url": "https://www.orthodb.org/?gene=A0A8V0YGH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P541", "url": "https://www.orthodb.org/?gene=F1P541", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292544", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P541-1", "url": "https://www.uniprot.org/uniprotkb/F1P541-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGSSAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCAHQDIRLGETLSEFKEFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGSCNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQRIAELQRQLAEEEPMETDQSSNMLSSIQSEVAKYQMLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKVQEAK", "length": 331, "header": "tr|F1P541-1|F1P541_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=UCHL5 PE=1 SV=3 CANONICAL=F1P541-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGG7-1", "url": "https://www.uniprot.org/uniprotkb/F1P541/entry#A0A8V0YGG7-1", "sequence": { "sequence": "MRPAVRSLALSFCRAYGGQAPLQRCRTSPSPAALVGSGLCCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCAHQDIRLGETLSEFKEFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGSCNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQRIAELQRQLAEEEPMETDQSSNMLSSIQSEVAKYQMLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKVQEAK", "length": 343, "header": "tr|A0A8V0YGG7-1|F1P541_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=UCHL5 PE=1 SV=1 CANONICAL=F1P541-1" }, "locus": { "chromosome": "8", "start_pos": 3531499, "end_pos": 3519571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030364.1", "url": "https://www.ensembl.org/id/ENSGALT00010030364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017615.1", "url": "https://www.ensembl.org/id/ENSGALP00010017615.1" } ] } }, { "isoform_ac": "A0A8V0YGH7-1", "url": "https://www.uniprot.org/uniprotkb/F1P541/entry#A0A8V0YGH7-1", "sequence": { "sequence": "MAGGSSAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCAHQDIRLGETLSEFKEFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGSCNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQRIAELQRQLAEEEPMETDQSSNMLSSIQSEVAKYQMLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLAKEKQNAKKVQEAK", "length": 328, "header": "tr|A0A8V0YGH7-1|F1P541_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=UCHL5 PE=1 SV=1 CANONICAL=F1P541-1" }, "locus": { "chromosome": "8", "start_pos": 3531499, "end_pos": 3519445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030389.1", "url": "https://www.ensembl.org/id/ENSGALT00010030389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017625.1", "url": "https://www.ensembl.org/id/ENSGALP00010017625.1" } ] } }, { "isoform_ac": "F1P541-1", "url": "https://www.uniprot.org/uniprotkb/F1P541/entry#F1P541-1", "sequence": { "sequence": "MAGGSSAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCAHQDIRLGETLSEFKEFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGSCNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQRIAELQRQLAEEEPMETDQSSNMLSSIQSEVAKYQMLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKVQEAK", "length": 331, "header": "tr|F1P541-1|F1P541_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=UCHL5 PE=1 SV=3 CANONICAL=F1P541-1" }, "locus": { "chromosome": "8", "start_pos": 3531499, "end_pos": 3519445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030382.1", "url": "https://www.ensembl.org/id/ENSGALT00010030382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017624.1", "url": "https://www.ensembl.org/id/ENSGALP00010017624.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424359", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424359", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HUN1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Uchl5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNAGEWCLMESDPGVFTELIKGFGCRGVQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHRDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK", "length": 329 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O04482-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "UCH2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDSDSLNNLRPVYGLIFLFKWQAGEKDERPTIQDQVSNLFFANQVINNACATQAILAILLNSPEVDIGPELSALKEFTKNFPSDLKGLAINNSDSIRAAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPISLGPCPGDQTGIEWLQMVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQREQLLQQANTCVDKSEAEAVNALIAEVGSGIEAASDKIVMEEEKFMKWRTENIRRKHNYIPFLFNFLKLLAEKKQLKPLIEKAKKQKTESST", "length": 330 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54N38-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "uch2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSENEGWCTIESDPGVFTELITKIGVKDIQVEELYTLDSSEYDRLKPVLGLIFLFKWEKEEENRTISDNENIFFANQVIQNACATQAILSVLLNSEGIELGEELSNFKSFVGDFPPMMKGEAIGNSELIKETHNSFTVQDPFIFSKKKNRKPSDAFHFISFIPFQGKVYELDGLKKGPYCLGDCTPDNWLEIATPFIQKRMEKYSQGEIRFNLMAVIKNRQTTLQEKILTLEKKKNDLEIKLSELNSGSGGDNKEESGGATPTTKEDLNFMINVVNNDIEEANNEILMEQEKFRNWKDENIRRKHNFTPLILNLIKGLAEKDNLQPLIQKAKDQISQKQQQHK", "length": 343 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9WUP7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "Uchl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTPAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK", "length": 329 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XSJ0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "UCHL5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK", "length": 328 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9XZ61-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Uch-L5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDGAGNWCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPAGKVVLDRENIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGLTLSNASQIRTVHNSFARPTLFELDTKNQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLGEIKSEQNWIDVVRPIIEKRMQRYSDGEIHFNLMALISDRQRIYEQQIEKLLNPAPNAMDTEEDRQAEISSLRTYIEYEIQKKKRYKVENVRRKHNYLPFIVELLKILGENGQLMPIYEKAKQRALEREQAQRKKDTD", "length": 324 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5K5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "UCHL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK", "length": 329 }, "evidence": [ { "id": "F1P541", "url": "https://omabrowser.org/oma/group/F1P541/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "lateral ventricle development", "id": "GO:0021670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021670", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "forebrain morphogenesis", "id": "GO:0048853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048853", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance in response to DNA damage", "id": "GO:1904507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904507", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1P541", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P541-1" ], "evidence": [ { "id": "R-GGA-5665854", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5665854" } ] }, { "id": "R-GGA-5689544", "name": "UCHL5 binds INO80 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N8Z4-1", "P53478-1", "A0A8V0ZPN6-1", "F1P541-1" ], "evidence": [ { "id": "R-GGA-5689544", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689544" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1P541", "gene_name": "UCHL5", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P541" }, { "id": "PS52048", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52048" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UCH catalytic", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 227, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6J1-1", "uniprot_ac": "A0A8V0Z6J1", "uniprot_id": "A0A8V0Z6J1_CHICK", "mass": { "chemical_mass": 55539.0, "monoisotopic_mass": 55539.0 }, "refseq": {}, "gene_names": [ { "name": "TBL1XR1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ] } ], "protein_names": [ { "name": "Transducin beta like 1X receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBL1XR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1", "locus": { "chromosome": "9", "start_pos": 17729994, "end_pos": 17605420, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018396", "url": "https://www.ensembl.org/id/ENSGALG00010018396" } ] } } ], "crossref": [ { "id": "A0A8V0Z6J1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6J1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039182", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039182", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426284", "url": "https://www.ncbi.nlm.nih.gov/gene/426284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426284", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426284", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GENQPIK", "url": "https://omabrowser.org/oma/group/GENQPIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXL1", "url": "https://www.orthodb.org/?gene=A0A1D5NXL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-400206", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9029569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NXL1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBU6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDEVCVLDLRK", "length": 512, "header": "tr|A0A8V0Z6J1-1|A0A8V0Z6J1_CHICK Isoform 1 of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A1D5NXL1-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK", "length": 513, "header": "tr|A0A1D5NXL1-1|A0A8V0Z6J1_CHICK Computationally mapped isoform of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17726938, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044620.1", "url": "https://www.ensembl.org/id/ENSGALT00010044620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026566.1", "url": "https://www.ensembl.org/id/ENSGALP00010026566.1" } ] } }, { "isoform_ac": "A0A3Q2UBU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A3Q2UBU6-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQVP", "length": 473, "header": "tr|A0A3Q2UBU6-1|A0A8V0Z6J1_CHICK Computationally mapped isoform of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17725741, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044592.1", "url": "https://www.ensembl.org/id/ENSGALT00010044592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026545.1", "url": "https://www.ensembl.org/id/ENSGALP00010026545.1" } ] } }, { "isoform_ac": "A0A8V0Z5V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A8V0Z5V6-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGLCIRPTEIALLVGSHGPTMNVYIAKMTVPDPCTAIVPIEPWPVHYSQT", "length": 552, "header": "tr|A0A8V0Z5V6-1|A0A8V0Z5V6_CHICK Computationally mapped isoform of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17727060, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044566.1", "url": "https://www.ensembl.org/id/ENSGALT00010044566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026528.1", "url": "https://www.ensembl.org/id/ENSGALP00010026528.1" } ] } }, { "isoform_ac": "A0A8V0Z6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A8V0Z6C1-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRFVY", "length": 457, "header": "tr|A0A8V0Z6C1-1|A0A8V0Z6C1_CHICK Computationally mapped isoform of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17726924, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044481.1", "url": "https://www.ensembl.org/id/ENSGALT00010044481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026475.1", "url": "https://www.ensembl.org/id/ENSGALP00010026475.1" } ] } }, { "isoform_ac": "A0A8V0Z6J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A8V0Z6J1-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDEVCVLDLRK", "length": 512, "header": "tr|A0A8V0Z6J1-1|A0A8V0Z6J1_CHICK Isoform 1 of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17726938, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044602.1", "url": "https://www.ensembl.org/id/ENSGALT00010044602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026552.1", "url": "https://www.ensembl.org/id/ENSGALP00010026552.1" } ] } }, { "isoform_ac": "A0A8V0ZDF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1/entry#A0A8V0ZDF2-1", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEVNAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK", "length": 498, "header": "tr|A0A8V0ZDF2-1|A0A8V0ZDF2_CHICK Computationally mapped isoform of Transducin beta like 1X receptor 1 OS=Gallus gallus OX=9031 GN=TBL1XR1 PE=1 SV=1 CANONICAL=A0A8V0Z6J1-1" }, "locus": { "chromosome": "9", "start_pos": 17726938, "end_pos": 17712378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044611.1", "url": "https://www.ensembl.org/id/ENSGALT00010044611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026559.1", "url": "https://www.ensembl.org/id/ENSGALP00010026559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426284", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426284", "resource": "KEGG Pathway" }, { "id": "R-GGA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-GGA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-GGA-9029569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029569", "resource": "Reactome", "description": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H7E9-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "Tbl1xr1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQHAAAAAAAAAATNQQGSAKNGENTANGEENGAHTITKIVASHDADNHTDLMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTNGPTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMRQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK", "length": 522 }, "evidence": [ { "id": "A0A8V0Z6J1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6J1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZNF4-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "Tbl1xr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQHAAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK", "length": 514 }, "evidence": [ { "id": "A0A8V0Z6J1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6J1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHJ5-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "Tbl1xr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQHAAAAAAAAAATNQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPSNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK", "length": 514 }, "evidence": [ { "id": "A0A8V0Z6J1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6J1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GFU3-1", "uniprot_ac": "R4GFU3", "uniprot_id": "R4GFU3_CHICK", "mass": { "chemical_mass": 120864.0, "monoisotopic_mass": 120864.0 }, "refseq": { "ac": "XP_015137750", "name": "semaphorin-5A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137750" }, "gene_names": [ { "name": "SEMA5A", "type": "recommended", "evidence": [ { "id": "R4GFU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ] }, { "name": "SEMA5A", "type": "synonym", "evidence": [ { "id": "XP_015137750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137750" } ] } ], "protein_names": [ { "name": "Semaphorin-5A", "type": "recommended", "evidence": [ { "id": "R4GFU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFU3/entry#names_and_taxonomy" } ] }, { "name": "Semaphorin-F", "type": "synonym", "evidence": [ { "id": "R4GFU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFU3/entry#names_and_taxonomy" } ] }, { "name": "semaphorin-5A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137750" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137750" } ] }, { "annotation": "Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3#function" }, { "database": "UniProtKB", "id": "ARBA00056685", "url": "https://www.uniprot.org/uniprotkb/ARBA00056685#function" }, { "database": "UniProtKB", "id": "A0A1D5PFR3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFR3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEMA5A", "url": "https://www.uniprot.org/uniprotkb/R4GFU3", "locus": { "chromosome": "2", "start_pos": 78577008, "end_pos": 78251804, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000802", "url": "https://www.ensembl.org/id/ENSGALG00010000802" } ] } } ], "crossref": [ { "id": "R4GFU3", "url": "https://alphafold.ebi.ac.uk/entry/R4GFU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028685", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028685", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420931", "url": "https://www.ncbi.nlm.nih.gov/gene/420931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420931", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHTRSTC", "url": "https://omabrowser.org/oma/group/YHTRSTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PFR3", "url": "https://www.orthodb.org/?gene=A0A1D5PFR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X0Z9", "url": "https://www.orthodb.org/?gene=A0A8V0X0Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GFU3", "url": "https://www.orthodb.org/?gene=R4GFU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137750", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFR3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X0Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X0Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X0Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X0Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFU3-1", "url": "https://www.uniprot.org/uniprotkb/R4GFU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTMKGSCLLVLLLAGFGVLGILEPDAEDIHCHRAVHPVITYKEIAPWLHVFKAEDAVDFSQLTFDPGQKELIAGARNYLFRLQLEDLSLIQAVEWQCDEATKRACYSKGKSKEECQNYIRVLLVGGNHLFTCGTNAFTPICTNRTLNNLTEIHDQISGMARCPYSPQHNSTALLTSSGELYAATAMDFPGRDPAIYRSLGALPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGKFVLEDTWTTFMKARLNCSRPGEIPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAITQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFFLMHEVVQPVIPIPYFMEDNSRFSHVVVDVVQGKDMLFHIIYLATDYGTIKKVLAPMNQTSSSCLLEEIELLPKSQREPIRSLQILHSQSVLFVGLQEHVIKVPLKRCLFYKTFSACIGSQDPYCGWDMVMKKCTTLEESLSMSQWEQSITVCPTRNLTVDGHFGTWSQWKPCSHTDGASTGSCLCRTRVCDSPAPQCGGWLCEGPTMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTSWGPWERCTAQCGGGIQARRRTCENGPDCPGCSVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRSGRYSAHTINGAWSPWSAWSQCSRDCSRGIRNRKRVCSNPEPKYGGLPCLGPSLEYQECNILPCPVDGGWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPDSWSEWSEWSECDSSGMQLRVRQCILLFPVGSQCTGNTTESRACAFDSNFIPEISVARSSSREEKRCGEFNMFHMIAVGLSSSILGCLLTLLIYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTAKTYSNTYFTDFNNYDEY", "length": 1076, "header": "tr|R4GFU3-1|R4GFU3_CHICK Isoform 1 of Semaphorin-5A OS=Gallus gallus OX=9031 GN=SEMA5A PE=4 SV=2 CANONICAL=R4GFU3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFR3-1", "url": "https://www.uniprot.org/uniprotkb/R4GFU3/entry#A0A1D5PFR3-1", "sequence": { "sequence": "MTTMKGSCLLVLLLAGFGVLGILEPDAEDIHCHRAVHPVITYKEIAPWLHVFKAEDAVDFSQLTFDPGQKELIAGARNYLFRLQLEDLSLIQAVEWQCDEATKRACYSKGKSKEECQNYIRVLLVGGNHLFTCGTNAFTPICTNRTLNNLTEIHDQISGMARCPYSPQHNSTALLTSSGELYAATAMDFPGRDPAIYRSLGALPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGKFVLEDTWTTFMKARLNCSRPGEIPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAITQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFFLMHEVVQPVIPIPYFMEDNSRFSHVVVDVVQGKDMLFHIIYLATDYGTIKKVLAPMNQTSSSCLLEEIELLPKSQREPIRSLQILHSQSVLFVGLQEHVIKVPLKRCLFYKTFSACIGSQDPYCGWDMVMKKCTTLEESLSMSQWEQSITVCPTRNLTVDGHFGTWSQWKPCSHTDGASTGSCLCRTRVCDSPAPQCGGWLCEGPTMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTSWGPWERCTAQCGGGIQARRRTCENGPDCPGCSVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRSGRYSAHTINGAWSPWSAWSQCSRDCSRGIRNRKRVCSNPEPKYGGLPCLGPSLEYQECNILPCPVDGGWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPDSWSEWSEWSECDSSGMQLRVRQCILLFPVGSQCTGNTTESRACAFDSNFIPEISVARSSSREEKRCGEFNMFHMIAVGLSSSILGCLLTLLIYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDSVEAIKKNSDV", "length": 1042, "header": "tr|A0A1D5PFR3-1|R4GFU3_CHICK Computationally mapped isoform of Semaphorin-5A OS=Gallus gallus OX=9031 GN=SEMA5A PE=4 SV=1 CANONICAL=R4GFU3-1" }, "locus": { "chromosome": "2", "start_pos": 78574763, "end_pos": 78353539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001759.1", "url": "https://www.ensembl.org/id/ENSGALT00010001759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000960.1", "url": "https://www.ensembl.org/id/ENSGALP00010000960.1" } ] } }, { "isoform_ac": "A0A8V0X0Z9-1", "url": "https://www.uniprot.org/uniprotkb/R4GFU3/entry#A0A8V0X0Z9-1", "sequence": { "sequence": "MASPDCGKGEMRITRMAEECQNYIRVLLVGGNHLFTCGTNAFTPICTNRTLNNLTEIHDQISGMARCPYSPQHNSTALLTSSGELYAATAMDFPGRDPAIYRSLGALPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGKFVLEDTWTTFMKARLNCSRPGEIPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAITQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFFLMHEVVQPVIPIPYFMEDNSRFSHVVVDVVQGKDMLFHIIYLATDYGTIKKVLAPMNQTSSSCLLEEIELLPKSQREPIRSLQILHSQSVLFVGLQEHVIKVPLKRCLFYKTFSACIGSQDPYCGWDMVMKKCTTLEESLSMSQWEQSITVCPTRNLTVDGHFGTWSQWKPCSHTDGASTGSCLCRTRVCDSPAPQCGGWLCEGPTMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTSWGPWERCTAQCGGGIQARRRTCENGPDCPGCSVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRSGRYSAHTINGAWSPWSAWSQCSRDCSRGIRNRKRVCSNPEPKYGGLPCLGPSLEYQECNILPCPVDGGWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPDSWSEWSEWSECDSSGMQLRVRQCILLFPVGSQCTGNTTESRACAFDSNFIPEISVARSSSREEKRCGEFNMFHMIAVGLSSSILGCLLTLLIYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTAKTYSNTYFTDFNNYDEY", "length": 980, "header": "tr|A0A8V0X0Z9-1|R4GFU3_CHICK Computationally mapped isoform of Semaphorin-5A OS=Gallus gallus OX=9031 GN=SEMA5A PE=4 SV=1 CANONICAL=R4GFU3-1" }, "locus": { "chromosome": "2", "start_pos": 78575619, "end_pos": 78438300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001756.1", "url": "https://www.ensembl.org/id/ENSGALT00010001756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000957.1", "url": "https://www.ensembl.org/id/ENSGALP00010000957.1" } ] } }, { "isoform_ac": "R4GFU3-1", "url": "https://www.uniprot.org/uniprotkb/R4GFU3/entry#R4GFU3-1", "sequence": { "sequence": "MTTMKGSCLLVLLLAGFGVLGILEPDAEDIHCHRAVHPVITYKEIAPWLHVFKAEDAVDFSQLTFDPGQKELIAGARNYLFRLQLEDLSLIQAVEWQCDEATKRACYSKGKSKEECQNYIRVLLVGGNHLFTCGTNAFTPICTNRTLNNLTEIHDQISGMARCPYSPQHNSTALLTSSGELYAATAMDFPGRDPAIYRSLGALPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGKFVLEDTWTTFMKARLNCSRPGEIPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAITQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFFLMHEVVQPVIPIPYFMEDNSRFSHVVVDVVQGKDMLFHIIYLATDYGTIKKVLAPMNQTSSSCLLEEIELLPKSQREPIRSLQILHSQSVLFVGLQEHVIKVPLKRCLFYKTFSACIGSQDPYCGWDMVMKKCTTLEESLSMSQWEQSITVCPTRNLTVDGHFGTWSQWKPCSHTDGASTGSCLCRTRVCDSPAPQCGGWLCEGPTMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTSWGPWERCTAQCGGGIQARRRTCENGPDCPGCSVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRSGRYSAHTINGAWSPWSAWSQCSRDCSRGIRNRKRVCSNPEPKYGGLPCLGPSLEYQECNILPCPVDGGWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPDSWSEWSEWSECDSSGMQLRVRQCILLFPVGSQCTGNTTESRACAFDSNFIPEISVARSSSREEKRCGEFNMFHMIAVGLSSSILGCLLTLLIYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTAKTYSNTYFTDFNNYDEY", "length": 1076, "header": "tr|R4GFU3-1|R4GFU3_CHICK Isoform 1 of Semaphorin-5A OS=Gallus gallus OX=9031 GN=SEMA5A PE=4 SV=2 CANONICAL=R4GFU3-1" }, "locus": { "chromosome": "2", "start_pos": 78575619, "end_pos": 78353539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001761.1", "url": "https://www.ensembl.org/id/ENSGALT00010001761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000962.1", "url": "https://www.ensembl.org/id/ENSGALP00010000962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420931", "resource": "KEGG Pathway" }, { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTD8-1", "protein_name": "Semaphorin-5A", "gene_name": "Sema5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGACILAWLFSSLGVWRLARPETQDPAKCQRAEHPVVSYKEIGPWLREFRAENAVDFSRLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVQWECDEATKKACYSKGKSKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTIRSLSNLTEIHDQISGMARCPYSPQHNSTALLTASGELYAATAMDFPGRDPAIYRSLGTLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAISQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTMDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGRDTLVHIIYLATDYGTIKKVRAPLSQSSGSCLLEEIELFPERKSEPIRSLKILHSQSVLFVGLQEHVVKIPLKRCHFHQTRGACIGAQDPYCGWDAVMKKCTSLEESLSMTQWDQSVPTCPTRNLTVDGSFGPWSPWTPCTHTDGTAVGSCLCRSRSCDSPAPQCGGWQCEGPRMEITNCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTGWGPWERCTAQCGGGIQARRRTCENGPDCAGCNVEYQPCNTNACPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEFQECNILPCPVDGVWSCWSSWSKCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQTCPENWSEWSEWSVCDASGTQVRTRQCILLFPVGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFNMFHMMAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAALNSSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY", "length": 1074 }, "evidence": [ { "id": "R4GFU3", "url": "https://omabrowser.org/oma/group/R4GFU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ML13-1", "protein_name": "Semaphorin-5A", "gene_name": "SEMA5A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKGPCVIAWLFSSLGWWRLAQLETDASLCQRAEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAAEWECDEATKKACYSKGKSQEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRTLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYHELQGTFFLPELDLIYGIFTTNVNSIAASAVCIFNLSAISQAFNGPFKYQENSRSAWLPYPNPNPNFQCGTVDQGVYMNLTERNLQDAQKFILMHEVVQPVSPVPAFMEDSSRFSHVAVDVVQARDALVHVIYLATDYGTIKKVRAPLTQTSGGCVLEEMELFPERRPEPVRSLRILHSQSVLFAGLREHVAKIPLKRCQFYRSRSACIGAQDPYCGWDLVMKKCTSLEESLSMTQWEQSIATCPVRNLTVDGHFGAWSPWTPCTHMDGSAVGSCLCRTRSCDSPAPQCGGWQCQGPRMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHVFWTGWGPWERCTAQCGGGIQARRRTCENGPDCAGCNVEYQPCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLPDPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKFGGMPCLGPSLEYQECNILPCPVDGMWSCWSSWSTCSATCGGGHYMRTRSCTNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSEWSECDVAGVQVRVRQCVLLFPVGSQCSGNTTESRPCIFDSNFIPEVSVARSSSIEEKRCGEFNLFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVAPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY", "length": 1073 }, "evidence": [ { "id": "R4GFU3", "url": "https://omabrowser.org/oma/group/R4GFU3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1R9L1-1", "protein_name": "Semaphorin-5A isoform X1", "gene_name": "sema5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGRPLARGLVLLHSLLLLMPRGVPCRGAIRALESPCHRAEHPLISHTDIEPWIHRFRAEGTVDYSQLTFDPGQNELIVGARNHLFRLHLEDLSLIQEAEWHCDEFTKGACFSRGKSEEECQNYIRVLLVNGDRLFTCGTNAFTPICTNRTLTNLTEVHDQISGMARCPYNPLHNSTALITSSGELYAATAMDFSGRDPAIYRSLGGLPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGRTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEIPFNYNELQGTFFLPELELLYGIFTTNVNSIAASAVCAFNLSAITQVFSGPFKYQENSRSAWLPYPNPNPDFQCGTIDFGSYVNLTERNLQDAQKFILMHEVVQPVVPVPYFMEDNVRFSHVAVDVVQGKDMLYHIIYLATDYGTIKKVLSPLNQTTGSCLLDEIELFPLKKRQPIRSLLILHSHSELFVGVREQVIKIPLMRCNFHKSREACVGARDPYCGWDLVLKKCTTLEESVSMSQWEQSITRCPVRNVTVDGHYGAWSGWKTCSHSDGGSVGSCQCRTRACDSPSPQCGGQPCQGISVEVANCSRNGAWTPWTAWAPCSTSCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLPCPPHVYWSAWSPWERCTVPCGGGIQSRRRTCENGNECPGCSTEFQSCNTLPCPDLKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARVPEPGLLEVGRQRIEMRYCSSDGSTGCSTDGDLLRSGRITGLTVNGGWSVWGPWSQCSRDCSSGVRNRKRTCSNPKPKYGGITCLGPAQEFQECNTTPCPVDGSWSCWSPWSKCSVTCGGGHYMRTRSCNNPPPAYGGDICLGLHTEEALCNIQPCPESWSDWSEWSPCDSSGSQVRLRHCDVLFPTGNQCSGNSSETRACLPISNFIPETSVARSSQEERWCGDFNVFHMIAVGLSSSILGCLVTLLVYTYCQRYQQQSHDATVIHPISAAPLNTSISNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPQLAGKTYTNAYFTDVNTYDDF", "length": 1078 }, "evidence": [ { "id": "R4GFU3", "url": "https://omabrowser.org/oma/group/R4GFU3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q13591-1", "protein_name": "Semaphorin-5A", "gene_name": "SEMA5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY", "length": 1074 }, "evidence": [ { "id": "R4GFU3", "url": "https://omabrowser.org/oma/group/R4GFU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "R4GFU3", "url": "https://www.uniprot.org/uniprotkb/R4GFU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": 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"https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 486, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GM28-1", "uniprot_ac": "R4GM28", "uniprot_id": "R4GM28_CHICK", "mass": { "chemical_mass": 59874.0, "monoisotopic_mass": 59874.0 }, "refseq": { "ac": "XP_015146520", "name": "mesoderm induction early response protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146520" }, "gene_names": [ { "name": "MIER1", "type": "recommended", "evidence": [ { "id": "R4GM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ] }, { "name": "MIER1", "type": "synonym", "evidence": [ { "id": "XP_015146520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146520" } ] } ], "protein_names": [ { "name": "Mesoderm induction early response protein 1", "type": "recommended", "evidence": [ { "id": "R4GM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#names_and_taxonomy" } ] }, { "name": "mesoderm induction early response protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015146520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146520" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146520" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIER1", "url": "https://www.uniprot.org/uniprotkb/R4GM28", "locus": { "chromosome": "8", "start_pos": 28303150, "end_pos": 28271702, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023186", "url": "https://www.ensembl.org/id/ENSGALG00010023186" } ] } } ], "crossref": [ { "id": "R4GM28", "url": "https://alphafold.ebi.ac.uk/entry/R4GM28", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011118", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011118", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424702", "url": "https://www.ncbi.nlm.nih.gov/gene/424702", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AD64", "url": "https://www.orthodb.org/?gene=A0A3Q3AD64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS09", "url": "https://www.orthodb.org/?gene=A0A8V0ZS09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV10", "url": "https://www.orthodb.org/?gene=A0A8V0ZV10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV15", "url": "https://www.orthodb.org/?gene=A0A8V0ZV15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZZH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GM28", "url": "https://www.orthodb.org/?gene=R4GM28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3AD64", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AD64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AD64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AD64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GM28-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTFVHHGGIGKSSALMSQEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 530, "header": "tr|R4GM28-1|R4GM28_CHICK Isoform 1 of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AD64-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#A0A3Q3AD64-1", "sequence": { "sequence": "MLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 486, "header": "tr|A0A3Q3AD64-1|R4GM28_CHICK Computationally mapped isoform of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28285026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056567.1", "url": "https://www.ensembl.org/id/ENSGALT00010056567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034309.1", "url": "https://www.ensembl.org/id/ENSGALP00010034309.1" } ] } }, { "isoform_ac": "A0A8V0ZS09-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#A0A8V0ZS09-1", "sequence": { "sequence": "MAEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKVNIKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 517, "header": "tr|A0A8V0ZS09-1|R4GM28_CHICK Computationally mapped isoform of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28272532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056582.1", "url": "https://www.ensembl.org/id/ENSGALT00010056582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034324.1", "url": "https://www.ensembl.org/id/ENSGALP00010034324.1" } ] } }, { "isoform_ac": "A0A8V0ZV10-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#A0A8V0ZV10-1", "sequence": { "sequence": "SAKPFIHSFFIVTKRGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 516, "header": "tr|A0A8V0ZV10-1|R4GM28_CHICK Computationally mapped isoform of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28284371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056558.1", "url": "https://www.ensembl.org/id/ENSGALT00010056558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034300.1", "url": "https://www.ensembl.org/id/ENSGALP00010034300.1" } ] } }, { "isoform_ac": "A0A8V0ZV15-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#A0A8V0ZV15-1", "sequence": { "sequence": "MMSKGFDLVRQESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 464, "header": "tr|A0A8V0ZV15-1|R4GM28_CHICK Computationally mapped isoform of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28288274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056563.1", "url": "https://www.ensembl.org/id/ENSGALT00010056563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034305.1", "url": "https://www.ensembl.org/id/ENSGALP00010034305.1" } ] } }, { "isoform_ac": "A0A8V0ZZH9-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#A0A8V0ZZH9-1", "sequence": { "sequence": "MLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 467, "header": "tr|A0A8V0ZZH9-1|R4GM28_CHICK Computationally mapped isoform of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28285026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056571.1", "url": "https://www.ensembl.org/id/ENSGALT00010056571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034313.1", "url": "https://www.ensembl.org/id/ENSGALP00010034313.1" } ] } }, { "isoform_ac": "R4GM28-1", "url": "https://www.uniprot.org/uniprotkb/R4GM28/entry#R4GM28-1", "sequence": { "sequence": "MCTFVHHGGIGKSSALMSQEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDETQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD", "length": 530, "header": "tr|R4GM28-1|R4GM28_CHICK Isoform 1 of Mesoderm induction early response protein 1 OS=Gallus gallus OX=9031 GN=MIER1 PE=4 SV=1 CANONICAL=R4GM28-1" }, "locus": { "chromosome": "8", "start_pos": 28300423, "end_pos": 28273099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056577.1", "url": "https://www.ensembl.org/id/ENSGALT00010056577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034319.1", "url": "https://www.ensembl.org/id/ENSGALP00010034319.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "R4GM28", "url": "https://www.uniprot.org/uniprotkb/R4GM28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GM28-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 530, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GM28-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GM28" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 400 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGG5-1", "uniprot_ac": "R4GGG5", "uniprot_id": "R4GGG5_CHICK", "mass": { "chemical_mass": 51970.0, "monoisotopic_mass": 51970.0 }, "refseq": { "ac": "NP_001243877", "name": "microfibrillar-associated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" }, "gene_names": [ { "name": "MFAP1", "type": "recommended", "evidence": [ { "id": "R4GGG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ] }, { "name": "AMF", "type": "synonym", "evidence": [ { "id": "NP_001243877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] }, { "name": "MFAP1", "type": "synonym", "evidence": [ { "id": "NP_001243877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] } ], "protein_names": [ { "name": "Microfibrillar associated protein 1", "type": "synonym", "evidence": [ { "id": "R4GGG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGG5/entry#names_and_taxonomy" } ] }, { "name": "associated microfibril protein", "type": "synonym", "evidence": [ { "id": "NP_001243877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] }, { "name": "microfibrillar-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001243877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] }, { "name": "spliceosome B complex protein MFAP1", "type": "synonym", "evidence": [ { "id": "NP_001243877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01013190.1, HAEL01002081.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000246.1. On Mar 9, 2012 this sequence version replaced XP_413954.2. Sequence Note: This RefSeq record was created from transcripts from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001243877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877" } ] }, { "annotation": "Involved in pre-mRNA splicing as a component of the spliceosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X266", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X266#function" }, { "database": "UniProtKB", "id": "ARBA00002609", "url": "https://www.uniprot.org/uniprotkb/ARBA00002609#function" }, { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFAP1", "url": "https://www.uniprot.org/uniprotkb/R4GGG5", "locus": { "chromosome": "10", "start_pos": 20149360, "end_pos": 20145572, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000059", "url": "https://www.ensembl.org/id/ENSGALG00010000059" } ] } } ], "crossref": [ { "id": "R4GGG5", "url": "https://alphafold.ebi.ac.uk/entry/R4GGG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028295", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028295", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415586", "url": "https://www.ncbi.nlm.nih.gov/gene/415586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415586", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHNERAG", "url": "https://omabrowser.org/oma/group/FHNERAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X266", "url": "https://www.orthodb.org/?gene=A0A8V0X266", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GGG5", "url": "https://www.orthodb.org/?gene=R4GGG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001243877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243877", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X266", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X266", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X266-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X266-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGG5-1", "url": "https://www.uniprot.org/uniprotkb/R4GGG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPSALVKQPPIQSTAGAVPVRNEKGELSMEKVKVKRYVSGKRPDYAPMESSEEEDEEFQFIKKAKEQEVEPEEQEEEVANDPRLRRLQNRITEDVEERLARHRKIVEPEVVGESDSEVEGEAWRVEREDTSEEEEEEIDDEEIERRRGMMRQRAQERKTEELEVMELEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRITVQEREAEALKQKELEQEAKRLAEERRKYTLKIVEEEAKKELEENKRSLAALDALDTDDENDEEEYEAWKVRELKRIKRDREEREAMEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439, "header": "tr|R4GGG5-1|R4GGG5_CHICK Isoform 1 of Microfibrillar associated protein 1 OS=Gallus gallus OX=9031 GN=MFAP1 PE=1 SV=1 CANONICAL=R4GGG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X266-1", "url": "https://www.uniprot.org/uniprotkb/R4GGG5/entry#A0A8V0X266-1", "sequence": { "sequence": "MSAPSALVKQPPIQSTAGAVPVRNEKGELSMEKVKVKRYVSGKRPDYAPMESSEEEDEEFQFIKKAKEQEEEVANDPRLRRLQNRITEDVEERLARHRKIVEPEVVGESDSEVEGEAWRVEREDTSEEEEEEIDDEEIERRRGMMRQRAQERKTEELEVMELEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRITVQEREAEALKQKELEQEAKRLAEERRKYTLKIVEEEAKKELEENKRSLAALDALDTDDENDEEEYEAWKVRELKRIKRDREEREAMEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 432, "header": "tr|A0A8V0X266-1|R4GGG5_CHICK Computationally mapped isoform of Microfibrillar associated protein 1 OS=Gallus gallus OX=9031 GN=MFAP1 PE=1 SV=1 CANONICAL=R4GGG5-1" }, "locus": { "chromosome": "10", "start_pos": 20148798, "end_pos": 20145683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000095.1", "url": "https://www.ensembl.org/id/ENSGALT00010000095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000071.1", "url": "https://www.ensembl.org/id/ENSGALP00010000071.1" } ] } }, { "isoform_ac": "R4GGG5-1", "url": "https://www.uniprot.org/uniprotkb/R4GGG5/entry#R4GGG5-1", "sequence": { "sequence": "MSAPSALVKQPPIQSTAGAVPVRNEKGELSMEKVKVKRYVSGKRPDYAPMESSEEEDEEFQFIKKAKEQEVEPEEQEEEVANDPRLRRLQNRITEDVEERLARHRKIVEPEVVGESDSEVEGEAWRVEREDTSEEEEEEIDDEEIERRRGMMRQRAQERKTEELEVMELEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRITVQEREAEALKQKELEQEAKRLAEERRKYTLKIVEEEAKKELEENKRSLAALDALDTDDENDEEEYEAWKVRELKRIKRDREEREAMEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439, "header": "tr|R4GGG5-1|R4GGG5_CHICK Isoform 1 of Microfibrillar associated protein 1 OS=Gallus gallus OX=9031 GN=MFAP1 PE=1 SV=1 CANONICAL=R4GGG5-1" }, "locus": { "chromosome": "10", "start_pos": 20148798, "end_pos": 20145683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000094.1", "url": "https://www.ensembl.org/id/ENSGALT00010000094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000070.1", "url": "https://www.ensembl.org/id/ENSGALP00010000070.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415586", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VC88-1", "protein_name": "Microfibril associated protein 1", "gene_name": "MFAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDTSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZMN0-1", "protein_name": "Microfibrillar-associated protein 1A like 1", "gene_name": "Mfap1al1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPSTLMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 438 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C0HKD8-1", "protein_name": "Microfibrillar-associated protein 1A", "gene_name": "Mfap1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRLEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKREREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD9-1", "protein_name": "Microfibrillar-associated protein 1B", "gene_name": "Mfap1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRLEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKREREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3H0T7-1", "protein_name": "Microfibrillar-associated protein 1", "gene_name": "Mfap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMELEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O22281-1", "protein_name": "Microfibrillar-associated protein-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSVTAGVSESAIAVREKLKGGIGQTKVRRYWPGKAPEWAEEAEEDDDVRMQKFSVLDRAFPKNDDLGVARKDDPRLRRLAQTKVENRDEVRADHRRIRQAEIISTEEEESRNQENRDEDDDEDALEERRRRIKEKNLRRAQEEAALLPLEEEDEIQEEEEEEEESEYETDSEDDMPGIALIKPVFVPKAERDTIAERERLEAEEEALEELAKRKLEQRKIETKQIVVEEVRKDEEIRKNILLEEANIGDVETDDELNEAEEYEVWKTREIGRIKRERDAREAMLREREEIEKLRNMTEQERRDWERKNPKPSSAQPKKKWNFMQKYYHKGAFFQADPDDEAGSAGTDGIFQRDFSAPTGEDRLDKSILPKVMQVKHFGRSGRTKWTHLVNEDTTDWSNPWTSNDPLREKYNKKMAGMDAPIAKPKGSKKMKDWET", "length": 435 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P55081-1", "protein_name": "Microfibrillar-associated protein 1", "gene_name": "MFAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54SU3-1", "protein_name": "Protein MFAP1 homolog", "gene_name": "mfap1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVASRIRDKLKNNLESSGGHSVVTSGTKVIRYRAGQRPDYAEAEDDQDSHFSNIQNQKSIKEAETNDPRLARFKNRSSNQDEPQSVEERKASRRRHHDDDNDNDTTTTTTTTTSRRIQKTEIIKEDDDNNNNNNNDTKKDHNDDDEDDDRRRRAKERYLKKKEEEEQKQKELEEKQQPFKDIEGESEEEGSSEYETDSEEDDEDEYWDQPPIFRPTFIKKDDRGTIKTDEQWEKEEQEQQAQLEREKEQRKIEAHRKLKDELDRDRKEQEAKELEQKEEEEYDDDEDQDGSKKLLWIQRELERVRLEIHTRLLAEFEKKEFARRRAMTDDQILKEDPSRSRTNIDNSQKKQLKFLQRDYHRGAFFQDDEYIKNKDFSAPTGEDKFNRELLPKVMQVKNFGKAGRTKYTHLKDQDTTEKDSLWNTNYNNKKKYNNNNNNSNSNSSNNNRDYNYRDRDNRS", "length": 460 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EA98-1", "protein_name": "Microfibrillar-associated protein 1", "gene_name": "MFAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVPSSLMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDPWRMEREDSSEEEEEEIDEEEIERRRGMMRQRAQERKNEELEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKHMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT", "length": 439 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9W062-1", "protein_name": "Microfibrillar-associated protein 1", "gene_name": "Mfap1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAATAAAAASGIQSTAGAIPMRNEKGELSMQKVKVQRYISGKRPDYARADSSSEESDDDDFIDTRKRLERHKAERHKLELSRQGGSAEGEERAAGEGQEEDDAEVDDPRLRRLRQRPVDMEDMERERRERHRHIHEPEIMESDSEDEEEDEGAQGAIQRGTNKITLASESDTDAELSDTELENRRTKLRSRMLQQQREEEVLQKEDEKQSESSESESSEYEEETESEEDNEPRLKPLFVRKRDRATIQEKEREAQKQKQLEAEAKRAAKERRRATLRMVEESVKKDLEKTKPETNEACIEDVCTDDENDEVEYEAWKLRELKRMKRDREERDNVEREKLDIDRMRNMTEEERRQELRQNPKVVTNKATKGKYKFLQKYYHRGAFYLDEENDVLKRDFAQATLEDHFDKTILPKVMQVKNFGRCGRTKYTHLVDQDTTKFDSPWYAESSSNIKFHNEHAGGMRQQFDKPTGSKRKKME", "length": 478 }, "evidence": [ { "id": "R4GGG5", "url": "https://omabrowser.org/oma/group/R4GGG5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "pmid": "" }, { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "R4GGG5", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GGG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GGG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GGG5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GGG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGG5" }, { "id": "PF06991", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06991" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Micro-fibrillar-associated protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 399, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 }, { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q8JG33-1", "uniprot_ac": "Q8JG33", "uniprot_id": "WFDC1_CHICK", "mass": { "chemical_mass": 25236.0, "monoisotopic_mass": 25236.0 }, "refseq": { "ac": "NP_989885", "name": "WAP four-disulfide core domain protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" }, "gene_names": [ { "name": "WFDC1", "type": "recommended", "evidence": [ { "id": "Q8JG33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ] }, { "name": "PS20", "type": "synonym", "evidence": [ { "id": "NP_989885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" }, { "id": "Q8JG33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ] }, { "name": "WFDC1", "type": "synonym", "evidence": [ { "id": "NP_989885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" } ] } ], "protein_names": [ { "name": "WAP four-disulfide core domain protein 1", "type": "recommended", "evidence": [ { "id": "Q8JG33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#names_and_taxonomy" } ] }, { "name": "Protein ps20", "type": "synonym", "evidence": [ { "id": "Q8JG33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#names_and_taxonomy" } ] }, { "name": "WAP four-disulfide core domain protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_989885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" } ] }, { "name": "WAP four-disulfide core domain protein 1", "type": "synonym", "evidence": [ { "id": "NP_989885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" } ] }, { "name": "protein ps20", "type": "synonym", "evidence": [ { "id": "NP_989885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ438290.1, ERR2365562.13127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000248.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885" } ] }, { "annotation": "Has growth inhibitory activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33#function" }, { "database": "UniProtKB", "id": "A0A8V0XVB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB8#function" }, { "database": "UniProtKB", "id": "ARBA00056452", "url": "https://www.uniprot.org/uniprotkb/ARBA00056452#function" }, { "database": "UniProtKB", "id": "A0A8V0XP19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP19#function" }, { "database": "UniProtKB", "id": "A0A8V0XY18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY18#function" }, { "database": "UniProtKB", "id": "A0A8V0Y156", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y156#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WFDC1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33", "locus": { "chromosome": "11", "start_pos": 16384318, "end_pos": 16368320, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007577", "url": "https://www.ensembl.org/id/ENSGALG00010007577" } ] } } ], "crossref": [ { "id": "Q8JG33", "url": "https://alphafold.ebi.ac.uk/entry/Q8JG33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005503", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005503", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395238", "url": "https://www.ncbi.nlm.nih.gov/gene/395238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395238", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFYKEYP", "url": "https://omabrowser.org/oma/group/RFYKEYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XP19", "url": "https://www.orthodb.org/?gene=A0A8V0XP19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVB8", "url": "https://www.orthodb.org/?gene=A0A8V0XVB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY18", "url": "https://www.orthodb.org/?gene=A0A8V0XY18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y156", "url": "https://www.orthodb.org/?gene=A0A8V0Y156", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q8JG33", "url": "https://www.orthodb.org/?gene=Q8JG33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14308:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14308:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q8JG33", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8JG33", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989885", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XP19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XP19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y156", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y156", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y156-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y156-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8JG33-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSRMLSDQRFCRRIFAAALCVLVLLADSGCARNLWKRALHLKMTEKYDDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLRGNPDGRNLRHKYYKEYFGSNSNNVVGYVKNQQKHLG", "length": 222, "header": "sp|Q8JG33-1|WFDC1_CHICK Isoform 1 of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XP19-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#A0A8V0XP19-1", "sequence": { "sequence": "MDSRMLSDQRFCRRIFAAALCVLVLLADSGCARNLWKRALHLKMTEKYDDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLHGRNLRHKYYKEYFGSNSNNVVGYVKNQQKHLG", "length": 218, "header": "tr|A0A8V0XP19-1|WFDC1_CHICK Computationally mapped isoform of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "locus": { "chromosome": "11", "start_pos": 16381161, "end_pos": 16372178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018052.1", "url": "https://www.ensembl.org/id/ENSGALT00010018052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009941.1", "url": "https://www.ensembl.org/id/ENSGALP00010009941.1" } ] } }, { "isoform_ac": "A0A8V0XVB8-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#A0A8V0XVB8-1", "sequence": { "sequence": "MAESHPEELFGVSRAFPQRTASSRGRQPSPSKDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLRGNPDGRNLRHKYYKEYFGSNSNNVVGYVKNQQKHLG", "length": 205, "header": "tr|A0A8V0XVB8-1|WFDC1_CHICK Computationally mapped isoform of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "locus": { "chromosome": "11", "start_pos": 16381161, "end_pos": 16368385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018059.1", "url": "https://www.ensembl.org/id/ENSGALT00010018059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009944.1", "url": "https://www.ensembl.org/id/ENSGALP00010009944.1" } ] } }, { "isoform_ac": "A0A8V0XY18-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#A0A8V0XY18-1", "sequence": { "sequence": "MDSRMLSDQRFCRRIFAAALCVLVLLADSGCARNLWKRALHLKMTEKYDDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLRGNPEIYDSLTHRWTQPEA", "length": 204, "header": "tr|A0A8V0XY18-1|WFDC1_CHICK Computationally mapped isoform of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "locus": { "chromosome": "11", "start_pos": 16380849, "end_pos": 16372178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018039.1", "url": "https://www.ensembl.org/id/ENSGALT00010018039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009934.1", "url": "https://www.ensembl.org/id/ENSGALP00010009934.1" } ] } }, { "isoform_ac": "A0A8V0Y156-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#A0A8V0Y156-1", "sequence": { "sequence": "MDSRMLSDQRFCRRIFAAALCVLVLLADSGCARNLWKRALHLKMTEKYDDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLRGNPDGRNLRHKYYKEYFAGPLY", "length": 208, "header": "tr|A0A8V0Y156-1|WFDC1_CHICK Computationally mapped isoform of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "locus": { "chromosome": "11", "start_pos": 16382133, "end_pos": 16372178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018056.1", "url": "https://www.ensembl.org/id/ENSGALT00010018056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009942.1", "url": "https://www.ensembl.org/id/ENSGALP00010009942.1" } ] } }, { "isoform_ac": "Q8JG33-1", "url": "https://www.uniprot.org/uniprotkb/Q8JG33/entry#Q8JG33-1", "sequence": { "sequence": "MDSRMLSDQRFCRRIFAAALCVLVLLADSGCARNLWKRALHLKMTEKYDDYEYPLHSHSAHYQKNDRCPPPPQTLPDRACEVPSCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNTAEGIPNRGQCIKLRGNPDGRNLRHKYYKEYFGSNSNNVVGYVKNQQKHLG", "length": 222, "header": "sp|Q8JG33-1|WFDC1_CHICK Isoform 1 of WAP four-disulfide core domain protein 1 OS=Gallus gallus OX=9031 GN=WFDC1 PE=2 SV=1 CANONICAL=Q8JG33-1" }, "locus": { "chromosome": "11", "start_pos": 16381161, "end_pos": 16372178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018057.1", "url": "https://www.ensembl.org/id/ENSGALT00010018057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009943.1", "url": "https://www.ensembl.org/id/ENSGALP00010009943.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATB8-1", "protein_name": "WAP four-disulfide core domain protein 1", "gene_name": "WFDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLTSRRMGSGRRKVSWALCFLLLLLEAAPAKNISKRALHVRLAERSRAEEAGGLRQPRADRCPPPPRSLPPGACQATRCQADSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQPKPRWLGGNGWLLDGPEETLQAEACSTTEDGAEPLLCPSGYECHILSPGDMAEGIPNRGQCVKQRRPADGRFLRHKFYKEYPEGASKNVAEHGKGQQRHFQ", "length": 217 }, "evidence": [ { "id": "Q8JG33", "url": "https://omabrowser.org/oma/group/Q8JG33/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1NF77-1", "protein_name": "WAP four-disulfide core domain protein 1", "gene_name": "wfdc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGIMQGCQMWTGFVPVLLISFFLLLESGSGNSRMIRKRGLNQKDYEYPNHPQTPQHQKNDRCPPPPQMLPERACEVPGCRSDSECERHKRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLLCPTGYECHIINPGNPSAGIPNRGQCIKQRGNSDGRSLRHKSFKDYKDYTGSNSNNAVNYEKHQHKHLG", "length": 220 }, "evidence": [ { "id": "Q8JG33", "url": "https://omabrowser.org/oma/group/Q8JG33/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9U1C5-1", "protein_name": "WAP four-disulfide core domain protein 1", "gene_name": "WFDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKVKSESEVAQSCPTPSQFYLPAGWGQRTHRLEHPSPLTIQEETPRTSCSMGSGRRKVSWTLCFLLLLLLEATSTKNLWKRALPSRLAERARVSAQAEEVGGSRQPRADRCPPPPRSLPPGACQAARCQADSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGAEPLLCPSGYECHILSPGDLAAGIPNRGQCVKQRKPADGRFLRQKFYKEYPEGASKYVAEHGQGQQRHFQ", "length": 265 }, "evidence": [ { "id": "Q8JG33", "url": "https://omabrowser.org/oma/group/Q8JG33/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9ESH5-1", "protein_name": "WAP four-disulfide core domain protein 1", "gene_name": "Wfdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNCGRKVLRALSFLLLLGSSSAQGTWEAMLPARLAEKSRAEEVAATGSRQPHADRCPPPPRTLPPGACQATRCQADSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAETCSTTEDGAEPLLCPSGYECHILQPGDEAQGIPNHGQCVKQRRQAEGRVLRQRLHKEYPEGDSKNVAEPGKGQQRHFP", "length": 211 }, "evidence": [ { "id": "Q8JG33", "url": "https://omabrowser.org/oma/group/Q8JG33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HC57-1", "protein_name": "WAP four-disulfide core domain protein 1", "gene_name": "WFDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLTGVGPGSCRRQIIRALCLLLLLLHAGSAKNIWKRALPARLAEKSRAEEAGAPGGPRQPRADRCPPPPRTLPPGACQAARCQADSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGAEPLLCPSGYECHILSPGDVAEGIPNRGQCVKQRRQADGRILRHKLYKEYPEGDSKNVAEPGRGQQKHFQ", "length": 220 }, "evidence": [ { "id": "Q8JG33", "url": "https://omabrowser.org/oma/group/Q8JG33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "Q8JG33", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q8JG33-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 222, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q8JG33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q8JG33" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q8JG33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JG33" }, { "id": "PRU00722", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00722" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WAP", "eco_id": "ECO_0000255", "start_pos": 61, "end_pos": 110, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q90WG1-1", "uniprot_ac": "Q90WG1", "uniprot_id": "SPINZ_CHICK", "mass": { "chemical_mass": 29624.0, "monoisotopic_mass": 29624.0 }, "refseq": { "ac": "NP_989964", "name": "spindlin-Z", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" }, "gene_names": [ { "name": "SPIN1", "type": "recommended", "evidence": [ { "id": "Q90WG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ] }, { "name": "SPINZ", "type": "recommended", "evidence": [ { "id": "Q90WG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ] }, { "name": "CHSPIN-Z", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "SPIN1Z", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "SPIN1", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "SPIN3", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "SPINZ", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "SPIN", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] } ], "protein_names": [ { "name": "Spindlin-Z", "type": "recommended", "evidence": [ { "id": "Q90WG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#names_and_taxonomy" } ] }, { "name": "chSpin-Z", "type": "synonym", "evidence": [ { "id": "Q90WG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#names_and_taxonomy" } ] }, { "name": "spindlin 1-Z", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "spindlin family, member 3", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "name": "spindlin-Z", "type": "synonym", "evidence": [ { "id": "NP_989964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB047853.1, SRR13267652.8524.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB047853.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ] }, { "annotation": "May play a role in mitosis.", "evidence": [ { "database": "UniProtKB", "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1#function" }, { "database": "PubMed", "id": "11419793", "url": "https://glygen.org/publication/PubMed/11419793" }, { "database": "UniProtKB", "id": "A0A8V0XVG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG4#function" }, { "database": "UniProtKB", "id": "ARBA00059636", "url": "https://www.uniprot.org/uniprotkb/ARBA00059636#function" }, { "database": "UniProtKB", "id": "A0A8V0XVI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI7#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C7#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8D7#function" } ] }, { "annotation": "Spin1z induces the male pathway in the chicken by down-regulating Tcf4.", "evidence": [ { "database": "RefSeq", "id": "NP_989964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" }, { "database": "PubMed", "id": "33631236", "url": "https://glygen.org/publication/PubMed/33631236" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPINZ", "url": "https://www.uniprot.org/uniprotkb/Q90WG1", "locus": {} } ], "crossref": [ { "id": "Q90WG1", "url": "https://alphafold.ebi.ac.uk/entry/Q90WG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014916", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395344", "url": "https://www.ncbi.nlm.nih.gov/gene/395344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395344", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VLPDRVX", "url": "https://omabrowser.org/oma/group/VLPDRVX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVG4", "url": "https://www.orthodb.org/?gene=A0A8V0XVG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVI7", "url": "https://www.orthodb.org/?gene=A0A8V0XVI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8C7", "url": "https://www.orthodb.org/?gene=A0A8V0Y8C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8D7", "url": "https://www.orthodb.org/?gene=A0A8V0Y8D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q90WG1", "url": "https://www.orthodb.org/?gene=Q90WG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q90WG1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q90WG1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XVG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90WG1-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTPFGKSPGQRSRADAGHAGVSASMMKKRTSHKKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 262, "header": "sp|Q90WG1-1|SPINZ_CHICK Isoform 1 of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XVG4-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#A0A8V0XVG4-1", "sequence": { "sequence": "MFIRTTDIHQKEFSCNFHENKKGRKIKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 254, "header": "tr|A0A8V0XVG4-1|SPINZ_CHICK Computationally mapped isoform of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "locus": { "chromosome": "Z", "start_pos": 43862430, "end_pos": 43855972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021493.1", "url": "https://www.ensembl.org/id/ENSGALT00010021493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012245.1", "url": "https://www.ensembl.org/id/ENSGALP00010012245.1" } ] } }, { "isoform_ac": "A0A8V0XVI7-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#A0A8V0XVI7-1", "sequence": { "sequence": "CRSCRSLCQHDEEKNIPQIRTTDIHQKEFSCNFHENKKGRKIKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 270, "header": "tr|A0A8V0XVI7-1|SPINZ_CHICK Computationally mapped isoform of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "locus": { "chromosome": "Z", "start_pos": 43862430, "end_pos": 43839793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021534.1", "url": "https://www.ensembl.org/id/ENSGALT00010021534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012271.1", "url": "https://www.ensembl.org/id/ENSGALP00010012271.1" } ] } }, { "isoform_ac": "A0A8V0Y8C7-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#A0A8V0Y8C7-1", "sequence": { "sequence": "MMGRLSELTFLQIRTTDIHQKEFSCNFHENKKGRKIKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 264, "header": "tr|A0A8V0Y8C7-1|SPINZ_CHICK Computationally mapped isoform of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "locus": { "chromosome": "Z", "start_pos": 43862430, "end_pos": 43854108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021504.1", "url": "https://www.ensembl.org/id/ENSGALT00010021504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012251.1", "url": "https://www.ensembl.org/id/ENSGALP00010012251.1" } ] } }, { "isoform_ac": "A0A8V0Y8D7-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#A0A8V0Y8D7-1", "sequence": { "sequence": "MKTPFGKSPGHAGVSASMMKKRTSHKKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 254, "header": "tr|A0A8V0Y8D7-1|SPINZ_CHICK Computationally mapped isoform of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "locus": { "chromosome": "Z", "start_pos": 43862430, "end_pos": 43839746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021518.1", "url": "https://www.ensembl.org/id/ENSGALT00010021518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012261.1", "url": "https://www.ensembl.org/id/ENSGALP00010012261.1" } ] } }, { "isoform_ac": "Q90WG1-1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1/entry#Q90WG1-1", "sequence": { "sequence": "MKTPFGKSPGQRSRADAGHAGVSASMMKKRTSHKKHRNNVGPSKPISQPRRNIVGCRIQHGWKEGSGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHKDERVSALEVLPDRVASSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPIMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 262, "header": "sp|Q90WG1-1|SPINZ_CHICK Isoform 1 of Spindlin-Z OS=Gallus gallus OX=9031 GN=SPINZ PE=2 SV=1 CANONICAL=Q90WG1-1" }, "locus": { "chromosome": "Z", "start_pos": 43862430, "end_pos": 43839746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021529.1", "url": "https://www.ensembl.org/id/ENSGALT00010021529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012266.1", "url": "https://www.ensembl.org/id/ENSGALP00010012266.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken spindlin genes on W and Z chromosomes: transcriptional expression of both genes and dynamic behavior of spindlin in interphase and mitotic cells.", "journal": "Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology", "date": "2001", "authors": "Itoh Y, Hori T, Saitoh H, Mizuno S", "evidence": [ { "database": "UniProtKB", "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ], "reference": [ { "type": "PubMed", "id": "11419793", "url": "https://glygen.org/publication/PubMed/11419793" } ] }, { "title": "Spin1z induces the male pathway in the chicken by down-regulating Tcf4.", "journal": "Gene", "date": "2021-05-15", "authors": "Jiang Jingyi, Zhang Chen, Yuan Xia, Li Jiancheng, Zhang Ming, Shi Xiang, Jin Kai, Zhang Yani, Zuo Qisheng, Chen Guohong, Li Bichun", "evidence": [ { "database": "RefSeq", "id": "NP_989964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989964" } ], "reference": [ { "type": "PubMed", "id": "33631236", "url": "https://glygen.org/publication/PubMed/33631236" } ] } ], "pathway": [ { "id": "gga:395344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395344", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q4V8J7-1", "protein_name": "Spindlin-1", "gene_name": "Spin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTPFGKTPGQRSRADAGHAGVSANMMKKRTSHKKHRTSVGPSKPVSQPRRNIVGCRIQHGWREGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELNKDDRVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "length": 262 }, "evidence": [ { "id": "Q90WG1", "url": "https://omabrowser.org/oma/group/Q90WG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "Q90WG1", "url": "https://www.uniprot.org/uniprotkb/Q90WG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q90WG1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 262, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q90WG1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q90WG1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q802A9-1", "uniprot_ac": "Q802A9", "uniprot_id": "FGFP2_CHICK", "mass": { "chemical_mass": 23261.0, "monoisotopic_mass": 23261.0 }, "refseq": { "ac": "NP_989778", "name": "fibroblast growth factor-binding protein 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" }, "gene_names": [ { "name": "FGFBP2", "type": "recommended", "evidence": [ { "id": "Q802A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q802A9" } ] }, { "name": "FGFBP2", "type": "synonym", "evidence": [ { "id": "NP_989778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" } ] } ], "protein_names": [ { "name": "Fibroblast growth factor-binding protein 2", "type": "recommended", "evidence": [ { "id": "Q802A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#names_and_taxonomy" } ] }, { "name": "FGF binding protein-2", "type": "synonym", "evidence": [ { "id": "NP_989778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" } ] }, { "name": "FGF-BP2", "type": "synonym", "evidence": [ { "id": "NP_989778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" }, { "id": "Q802A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#names_and_taxonomy" } ] }, { "name": "FGF-binding protein 2", "type": "synonym", "evidence": [ { "id": "Q802A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#names_and_taxonomy" } ] }, { "name": "FGFBP-2", "type": "synonym", "evidence": [ { "id": "NP_989778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" }, { "id": "Q802A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#names_and_taxonomy" } ] }, { "name": "fibroblast growth factor-binding protein 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_989778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01005971.1, BX929579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000074.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" } ] }, { "annotation": "FGF-binding proteins play a significant role in fine-tuning the complex FGF signaling network during distinct phases of embryonic development", "evidence": [ { "database": "RefSeq", "id": "NP_989778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778" }, { "database": "PubMed", "id": "19433791", "url": "https://glygen.org/publication/PubMed/19433791" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q802A9", "url": "https://www.uniprot.org/uniprotkb/Q802A9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGFBP2", "url": "https://www.uniprot.org/uniprotkb/Q802A9", "locus": { "chromosome": "4", "start_pos": 76101433, "end_pos": 76098099, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010467", "url": "https://www.ensembl.org/id/ENSGALG00010010467" } ] } } ], "crossref": [ { "id": "Q802A9", "url": "https://alphafold.ebi.ac.uk/entry/Q802A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014501", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395094", "url": "https://www.ncbi.nlm.nih.gov/gene/395094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q802A9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q802A9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR010510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395094", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGKSYWC", "url": "https://omabrowser.org/oma/group/QGKSYWC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y0Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Y0Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q802A9", "url": "https://www.orthodb.org/?gene=Q802A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15258:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15258:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q802A9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q802A9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-190377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y0Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y0Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q802A9", "url": "https://www.uniprot.org/uniprotkb/Q802A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q802A9-1", "url": "https://www.uniprot.org/uniprotkb/Q802A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRVALLFLVVICGMGGLGQKLKPKKRSNGEEINFRTKTKDVCTMRISGDEEMKARIECKGQGKSYWCEYTGMPLLCHPFQNNPKMYWNQITMELRKLPHACESTQMLKASMCQKAPVDALMKQVAAGVEPEDGANRDKSSQKTSASVRGAGKSSVKKTGKPAVLPRIKPTQHGQGSENETEAMKLAREHCWESLHEFCSYIIGFFRG", "length": 208, "header": "sp|Q802A9-1|FGFP2_CHICK Isoform 1 of Fibroblast growth factor-binding protein 2 OS=Gallus gallus OX=9031 GN=FGFBP2 PE=2 SV=1 CANONICAL=Q802A9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y0Y1-1", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#A0A8V0Y0Y1-1", "sequence": { "sequence": "MQRCCIQGHFAEGSQSVPLAMKRVALLFLVVICGMGGLGQKLKPKKRSNGEEINFRTKTKDVCTMRISGDEEMKARIECKGQGKSYWCEYTGMPLLCHPFQNNPKMYWNQITMELRKLPHACESTQMLKASMCQKAPVDALMKQVAAGVEPEDGANRDKSSQKTSASVRGAGKSSVKKTGKPAVLPRIKPTQHGQGSENETEAMKLAREHCWESLHEFCSYIIGFFRG", "length": 228, "header": "tr|A0A8V0Y0Y1-1|FGFP2_CHICK Computationally mapped isoform of Fibroblast growth factor-binding protein 2 OS=Gallus gallus OX=9031 GN=FGFBP2 PE=2 SV=1 CANONICAL=Q802A9-1" }, "locus": { "chromosome": "4", "start_pos": 76100207, "end_pos": 76098298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025015.1", "url": "https://www.ensembl.org/id/ENSGALT00010025015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014218.1", "url": "https://www.ensembl.org/id/ENSGALP00010014218.1" } ] } }, { "isoform_ac": "Q802A9-1", "url": "https://www.uniprot.org/uniprotkb/Q802A9/entry#Q802A9-1", "sequence": { "sequence": "MKRVALLFLVVICGMGGLGQKLKPKKRSNGEEINFRTKTKDVCTMRISGDEEMKARIECKGQGKSYWCEYTGMPLLCHPFQNNPKMYWNQITMELRKLPHACESTQMLKASMCQKAPVDALMKQVAAGVEPEDGANRDKSSQKTSASVRGAGKSSVKKTGKPAVLPRIKPTQHGQGSENETEAMKLAREHCWESLHEFCSYIIGFFRG", "length": 208, "header": "sp|Q802A9-1|FGFP2_CHICK Isoform 1 of Fibroblast growth factor-binding protein 2 OS=Gallus gallus OX=9031 GN=FGFBP2 PE=2 SV=1 CANONICAL=Q802A9-1" }, "locus": { "chromosome": "4", "start_pos": 76102413, "end_pos": 76101433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"R-GGA-190377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190377", "resource": "Reactome", "description": "FGFR2b ligand binding and activation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BYJ0-1", "protein_name": "Fibroblast growth factor-binding protein 2", "gene_name": "FGFBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFVPCLLLVTLSCLGTLGQAPRQKQGSTGEEFHFQTGGRDSCTMRPSSLGQGAGEVWLRVDCRNTDQTYWCEYRGQPSMCQAFAADPKPYWNQALQELRRLHHACQGAPVLRPSVCREAGPQAHMQQVTSSLKGSPEPNQQPEAGTPSLRPKATVKLTEATQLGKDSMEELGKAKPTTRPTAKPTQPGPRPGGNEEAKKKAWEHCWKPFQALCAFLISFFRG", "length": 223 }, "evidence": [ { "id": "Q802A9", "url": "https://omabrowser.org/oma/group/Q802A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": 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"uniprot_ac": "Q8UVV7", "uniprot_id": "LIX1_CHICK", "mass": { "chemical_mass": 31952.0, "monoisotopic_mass": 31952.0 }, "refseq": { "ac": "NP_989678", "name": "protein limb expression 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" }, "gene_names": [ { "name": "LIX1", "type": "recommended", "evidence": [ { "id": "Q8UVV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7" } ] }, { "name": "LIX1", "type": "synonym", "evidence": [ { "id": "NP_989678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ] } ], "protein_names": [ { "name": "Protein limb expression 1", "type": "recommended", "evidence": [ { "id": "Q8UVV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7/entry#names_and_taxonomy" } ] }, { "name": "Lix1 homolog", "type": "synonym", "evidence": [ { "id": "NP_989678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ] }, { "name": "limb expression 1", "type": "synonym", "evidence": [ { "id": "NP_989678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ] }, { "name": "protein limb expression 1", "type": "synonym", "evidence": [ { "id": "NP_989678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.87074.1, AF351203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000095.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ] }, { "annotation": "Expression of LIX1 must be tightly regulated to allow fine-tuning of the transcript levels and state of activation of the pro-proliferative transcriptional coactivator YAP1 to regulate proliferation rates of stomach mesenchymal progenitors and their differentiation Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" }, { "database": "PubMed", "id": "27125505", "url": "https://glygen.org/publication/PubMed/27125505" } ] }, { "annotation": "LIX1 is expressed during early chicken limb development in the nascent hindlimb bud. LIX1 is also expressed in the basal plate of rhombomeres 3 and 5, in pharyngeal and in foregut mesenchyme and in all facial primordia except for the mandibular arches.", "evidence": [ { "database": "RefSeq", "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" }, { "database": "PubMed", "id": "11731258", "url": "https://glygen.org/publication/PubMed/11731258" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8UVV7", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LIX1", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7", "locus": { "chromosome": "Z", "start_pos": 52262196, "end_pos": 52232025, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011893", 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"https://omabrowser.org/oma/group/AMLQEFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6L9", "url": "https://www.orthodb.org/?gene=A0A8V0Y6L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q8UVV7", "url": "https://www.orthodb.org/?gene=Q8UVV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14954", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14954", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q8UVV7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8UVV7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8UVV7", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8UVV7-1", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRTLESLQLVIARVLPHRDPALVFKDLNVVAILQEFWESKQKKKAVLPSEGIIVYESLSSLGPPFVSYVTLPGGSCFGNFQSCLSRAEARRDAAKVALINSLFNELPCRRITKEFIMESVQEAVSSTSGNLKDADDPSTSIGAYHYMLESNIGKTMLEFQELMIVFQLLHWNGSLKALRETKCSRQEVISYYSQCSLDEKMRSHMALDWIMKEQESPGIISQELQVALRELEEVRKAGHELRFYKEKKEILSLALSQIYSDEVTTSSWDNQMSLALHGYR", "length": 281, "header": "sp|Q8UVV7-1|LIX1_CHICK Isoform 1 of Protein limb expression 1 OS=Gallus gallus OX=9031 GN=LIX1 PE=2 SV=1 CANONICAL=Q8UVV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6L9-1", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7/entry#A0A8V0Y6L9-1", "sequence": { "sequence": "MDRTLESLQLVIARVLPHRDPALVFKDLNVVAILQEFWESKQKKKAVLPSEGIIVYESLSSLGPPFVSYVTLPGGSCFGNFQSCLSRAEARRDAAKVALINSLFNELPCRRITKEFIMESVQEAVSSTSGNLKDADDPSTSIGAYHYMLESNIGKTMLEFQEVISYYSQCSLDEKMRSHMALDWIMKEQESPGIISQELQVALRELEEVRKAGHELRFYKEKKEILSLALSQIYSDEVTTSSWDNQMSLALHGYR", "length": 255, "header": "tr|A0A8V0Y6L9-1|LIX1_CHICK Computationally mapped isoform of Protein limb expression 1 OS=Gallus gallus OX=9031 GN=LIX1 PE=2 SV=1 CANONICAL=Q8UVV7-1" }, "locus": { "chromosome": "Z", "start_pos": 52260562, "end_pos": 52232310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028433.1", "url": "https://www.ensembl.org/id/ENSGALT00010028433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016306.1", "url": "https://www.ensembl.org/id/ENSGALP00010016306.1" } ] } }, { "isoform_ac": "Q8UVV7-1", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7/entry#Q8UVV7-1", "sequence": { "sequence": "MDRTLESLQLVIARVLPHRDPALVFKDLNVVAILQEFWESKQKKKAVLPSEGIIVYESLSSLGPPFVSYVTLPGGSCFGNFQSCLSRAEARRDAAKVALINSLFNELPCRRITKEFIMESVQEAVSSTSGNLKDADDPSTSIGAYHYMLESNIGKTMLEFQELMIVFQLLHWNGSLKALRETKCSRQEVISYYSQCSLDEKMRSHMALDWIMKEQESPGIISQELQVALRELEEVRKAGHELRFYKEKKEILSLALSQIYSDEVTTSSWDNQMSLALHGYR", "length": 281, "header": "sp|Q8UVV7-1|LIX1_CHICK Isoform 1 of Protein limb expression 1 OS=Gallus gallus OX=9031 GN=LIX1 PE=2 SV=1 CANONICAL=Q8UVV7-1" }, "locus": { "chromosome": "Z", "start_pos": 52260562, "end_pos": 52232310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028435.1", "url": "https://www.ensembl.org/id/ENSGALT00010028435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016308.1", "url": "https://www.ensembl.org/id/ENSGALP00010016308.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cloning and expression analysis of chicken Lix1, a founding member of a novel gene family.", "journal": "Mech. Dev.", "date": "2001", "authors": "Swindell EC, Moeller C, Thaller C, Eichele G", "evidence": [ { "database": "UniProtKB", "id": "Q8UVV7", "url": "https://www.uniprot.org/uniprotkb/Q8UVV7" }, { "database": "RefSeq", "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ], "reference": [ { "type": "PubMed", "id": "11731258", "url": "https://glygen.org/publication/PubMed/11731258" } ] }, { "title": "LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors.", "journal": "BMC biology", "date": "2016-04-28", "authors": "McKey Jennifer, Martire Delphine, de Santa Barbara Pascal, Faure Sandrine", "evidence": [ { "database": "RefSeq", "id": "NP_989678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989678" } ], "reference": [ { "type": "PubMed", "id": "27125505", "url": "https://glygen.org/publication/PubMed/27125505" } ] } ], "pathway": [ { "id": "gga:374264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BF97-1", "protein_name": "Protein limb expression 1 homolog", "gene_name": "lix1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGADSDDDRAFKDLNVVGMLHKFWEQKQAAGVMMEIENLVVYESIPSPSPPFICYVTLPGGSCFGNFKHCYSKAEARRDAARVALMNSTFNELPCRRITPEFISHSVKEAVSTTSGNIADASDPSTSIGAYCLMLELNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKELQSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSLALSHADAEDLEEEMSWREATEFDCFEERRTDTNESCQFHSQGSDGESLE", "length": 290 }, "evidence": [ { "id": "Q8UVV7", "url": "https://omabrowser.org/oma/group/Q8UVV7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZAG6-1", "protein_name": "Limb and CNS expressed 1", "gene_name": "Lix1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GKR1-1", "uniprot_ac": "R4GKR1", "uniprot_id": "R4GKR1_CHICK", "mass": { "chemical_mass": 48848.0, "monoisotopic_mass": 48848.0 }, "refseq": { "ac": "NP_001243081", "name": "interleukin-5 receptor subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" }, "gene_names": [ { "name": "IL5RA", "type": "recommended", "evidence": [ { "id": "R4GKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ] }, { "name": "IL5RA", "type": "synonym", "evidence": [ { "id": "NP_001243081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" } ] } ], "protein_names": [ { "name": "Interleukin 5 receptor subunit alpha", "type": "synonym", "evidence": [ { "id": "R4GKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR1/entry#names_and_taxonomy" } ] }, { "name": "interleukin 5 receptor, alpha", "type": "synonym", "evidence": [ { "id": "NP_001243081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" } ] }, { "name": "interleukin-5 receptor subunit alpha", "type": "synonym", "evidence": [ { "id": "NP_001243081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB618610.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA2812691 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. On Jan 12, 2012 this sequence version replaced XP_001235031.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001243081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" } ] }, { "annotation": "Study identified a full-length cDNA encoding chicken IL-5R alpha-chain (chIL-5Ralpha). The deduced amino acid sequence showed 41-43% identity to mammalian homologues. It has four well-conserved cysteines and a WSXWS motif in the extracellular region, and a PPXP motif in the cytoplasmic region.", "evidence": [ { "database": "RefSeq", "id": "NP_001243081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" }, { "database": "PubMed", "id": "22391510", "url": "https://glygen.org/publication/PubMed/22391510" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL5RA", "url": "https://www.uniprot.org/uniprotkb/R4GKR1", "locus": { "chromosome": "12", "start_pos": 18269804, "end_pos": 18285463, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020457", "url": "https://www.ensembl.org/id/ENSGALG00010020457" } ] } } ], "crossref": [ { "id": "R4GKR1", "url": "https://alphafold.ebi.ac.uk/entry/R4GKR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008267", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008267", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771801", "url": "https://www.ncbi.nlm.nih.gov/gene/771801", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771801", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771801", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKFRDPF", "url": "https://omabrowser.org/oma/group/NKFRDPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7L4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GKR1", "url": "https://www.orthodb.org/?gene=R4GKR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-512988", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-512988", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912526", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001243081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKR1-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFLTDHLNFMASMMRVCLILLWIRILVQPHILQLKAVQVFPPINFTLTVSALAQVLLSWKPSPNQEQKNYTIRYDVKILTPVFEEYDTTKTHSFQTAVLHNGFSAHVRTLLFHKGLQMTSDWVTAELQPPPGAENTAVTDLSCVTHFTVSSTVSLHCTWLPGKEAPEDTKYFLFYRYETYTEECQDYIKDKWNRNVECRFSVTHIAPGEIDELIVIHINGSSKYAAIKPFQQLFNQNAIEKVNVPRNVTVFLEQNDLVATWEKPLSTFPKGCFEYEFYLINLKSGNEQVSKTYSHDFRLRIDVTGRYSVQIRANHHKCAVNGFWSDWSETLYIGENKQENLIVWSLTVLCVSTCSTVTLIAIVCKSQHMWRKLFPPIPTPRIKFRDPFPNHYERARSCPSETWLEPGGLAEGLPCSALHDNVF", "length": 424, "header": "tr|R4GKR1-1|R4GKR1_CHICK Isoform 1 of Interleukin 5 receptor subunit alpha OS=Gallus gallus OX=9031 GN=IL5RA PE=4 SV=2 CANONICAL=R4GKR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7L4-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1/entry#A0A8V0Z7L4-1", "sequence": { "sequence": "MVFLTDHLNFMASMMRVCLILLWIRILVQPHILQLKAVQVFPPINFTLTVSALAQVLLSWKPSPNQEQKNYTIRYDVKILTPVFEEYDTTKTHSFQTAVLHNGFSAHVRTLLFHKGLQMTSDWVTAELQPPPGAENTAVTDLSCVTHFTVSSTVSLHCTWLPGKEAPEDTKYFLFYRYETYTEECQDYIKDKWNRNVECRFSVTHIAPGEIDELIVIHINGSSKYAAIKPFQQLFNQNAIEKVNVPRNVTVFLEQNDLVATWEKPLSTFPKGCFEYEFYLINLKSGNEQVSKTYSHDFRLRIDVTGRYSVQIRANHHKCAVNGFWSDWSETLYIGENKQENLIVWSLTVLCVSTCSTVTLIAIKNKYTELLAAVSF", "length": 376, "header": "tr|A0A8V0Z7L4-1|A0A8V0Z7L4_CHICK Computationally mapped isoform of Interleukin 5 receptor subunit alpha OS=Gallus gallus OX=9031 GN=IL5RA PE=4 SV=1 CANONICAL=R4GKR1-1" }, "locus": { "chromosome": "12", "start_pos": 18283473, "end_pos": 18276304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049474.1", "url": "https://www.ensembl.org/id/ENSGALT00010049474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029239.1", "url": "https://www.ensembl.org/id/ENSGALP00010029239.1" } ] } }, { "isoform_ac": "A0A8V0ZEG3-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1/entry#A0A8V0ZEG3-1", "sequence": { "sequence": "MVFLTDHLNFMASMMRVCLILLWIRILVQPHILQLKAVQVFPPINFTLTVSALAQVLLSWKPSPNQEQKNYTIRYDVKILTPVFEEYDTTKTHSFQTAVLHNGFSAHVRTLLFHKGLQMTSDWVTAELQPPPGAENTAVTDLSCVTHFTVSSTVSLHCTWLPGKEAPEDTKYFLFYRYETYTEECQDYIKDKWNRNVECRFSVTHIAPGEIDELIVIHINGSSKYAAIKPFQQLFNQNAIEKVNVPRNVTVFLEQNDLVATWEKPLSTFPKGCFEYEFYLINLKSGNEQVSKTYSHDFRLRIDVTGRYSVQIRANHHKCAVNGFWSDWSETLYIGENKQENLIVWSLTVLCVSTCSTVTLIAIVCKSVLQKKTKTILRASL", "length": 381, "header": "tr|A0A8V0ZEG3-1|A0A8V0ZEG3_CHICK Computationally mapped isoform of Interleukin 5 receptor subunit alpha OS=Gallus gallus OX=9031 GN=IL5RA PE=4 SV=1 CANONICAL=R4GKR1-1" }, "locus": { "chromosome": "12", "start_pos": 18283473, "end_pos": 18274867, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049483.1", "url": "https://www.ensembl.org/id/ENSGALT00010049483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029243.1", "url": "https://www.ensembl.org/id/ENSGALP00010029243.1" } ] } }, { "isoform_ac": "R4GKR1-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1/entry#R4GKR1-1", "sequence": { "sequence": "MVFLTDHLNFMASMMRVCLILLWIRILVQPHILQLKAVQVFPPINFTLTVSALAQVLLSWKPSPNQEQKNYTIRYDVKILTPVFEEYDTTKTHSFQTAVLHNGFSAHVRTLLFHKGLQMTSDWVTAELQPPPGAENTAVTDLSCVTHFTVSSTVSLHCTWLPGKEAPEDTKYFLFYRYETYTEECQDYIKDKWNRNVECRFSVTHIAPGEIDELIVIHINGSSKYAAIKPFQQLFNQNAIEKVNVPRNVTVFLEQNDLVATWEKPLSTFPKGCFEYEFYLINLKSGNEQVSKTYSHDFRLRIDVTGRYSVQIRANHHKCAVNGFWSDWSETLYIGENKQENLIVWSLTVLCVSTCSTVTLIAIVCKSQHMWRKLFPPIPTPRIKFRDPFPNHYERARSCPSETWLEPGGLAEGLPCSALHDNVF", "length": 424, "header": "tr|R4GKR1-1|R4GKR1_CHICK Isoform 1 of Interleukin 5 receptor subunit alpha OS=Gallus gallus OX=9031 GN=IL5RA PE=4 SV=2 CANONICAL=R4GKR1-1" }, "locus": { "chromosome": "12", "start_pos": 18283473, "end_pos": 18272002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049490.1", "url": "https://www.ensembl.org/id/ENSGALT00010049490.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029247.1", "url": "https://www.ensembl.org/id/ENSGALP00010029247.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Molecular cloning of chicken interleukin-5 receptor \u03b1-chain and analysis of its binding specificity.", "journal": "Developmental and comparative immunology", "date": "2012-07", "authors": "Fukushima Yuji, Miyai Tomohiro, Kumagae Manami, Horiuchi Hiroyuki, Furusawa Shuichi", "evidence": [ { "database": "RefSeq", "id": "NP_001243081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243081" } ], "reference": [ { "type": "PubMed", "id": "22391510", "url": "https://glygen.org/publication/PubMed/22391510" } ] } ], "pathway": [ { "id": "gga:771801", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771801", "resource": "KEGG Pathway" }, { "id": "R-GGA-512988", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-512988", "resource": "Reactome", "description": "Interleukin-3, Interleukin-5 and GM-CSF signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-912526", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "resource": "Reactome", "description": "Interleukin receptor SHC signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N0Z3-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "Il5ra", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPALLILVGAWATLQADLLSDRKVLLLPPVNFTIKATGLAQVRLRWDPHPDQEQRDVDLQYHVKINAPREDEYNTRKTESKYVAPLHDGFAASVRSILWRSHSLLASSWVSAELKASPGSSGTSVINLTCTTNTVLSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYRFGIWTEECQEYSRDALNRNTACWFPRTFINSKGFDKLAVHVNGSSKHAAIKPFDQLFTPHAIDQVNPPMNVTVEIEETSLYIQWEKPVSAFPVHCFNYELKIYNTKNGYFQIEKLATNRFISKIDDVSTYSIQVRAVVSSSCRASGSWGEWSQPLYVGKEKKPLAEWHLIVFPATACFVLLIFSFICRVCHIWIKLFPPVPAPKSNIKDLLVVTDYEKAAWNETKIEVVSCVEEAGFEVMESSVF", "length": 416 }, "evidence": [ { "id": "R4GKR1", "url": "https://omabrowser.org/oma/group/R4GKR1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6A448-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "Il5ra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNSLIYCWRVAASFPYKRQHSELGRLSSTFPTTMVPVLLILMGASATLHADLLSPEKFLLLPPVNFTIKATGLAQVLLHWDPNPDQAPVDLEYHVKINVPQEDEYDTKNTESKCVTPLHEGFAASVRTILKSIHSPLASSWVSAELKAPPGSSGTSVMNLTCTTNTVKSSHTHFRPYQVSLRCTWLVGKDAPEDTQYFLYYRFSVWTEECQEYSKDALNRNIACWFPRTFINSKGFEQLAVHINGSSKHAAIKPLDQLFTLYAIDQVNPPMNVTVEIENNSLYIQWGKPLSAFPVHCFKYKLKIYNTKNGYSQMENLVTNKFISKIDDVSTYSIQVRAAVSSPCRMSGSWGEWSQPIYVGKKKKPLVEWHLIVLPTAICFILLIFSLICRVYHLWTRLFPPVPAPKSSIKDLPVVTEYEMYCFACSIGTRPAQAERAVSSAVLTDAQRYGGGTETQGSLIMEKWQEIDS", "length": 470 }, "evidence": [ { "id": "R4GKR1", "url": "https://omabrowser.org/oma/group/R4GKR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21183-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "Il5ra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPVLLILVGALATLQADLLNHKKFLLLPPVNFTIKATGLAQVLLHWDPNPDQEQRHVDLEYHVKINAPQEDEYDTRKTESKCVTPLHEGFAASVRTILKSSHTTLASSWVSAELKAPPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYRFGVLTEKCQEYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSKRAAIKPFDQLFSPLAIDQVNPPRNVTVEIESNSLYIQWEKPLSAFPDHCFNYELKIYNTKNGHIQKEKLIANKFISKIDDVSTYSIQVRAAVSSPCRMPGRWGEWSQPIYVGKERKSLVEWHLIVLPTAACFVLLIFSLICRVCHLWTRLFPPVPAPKSNIKDLPVVTEYEKPSNETKIEVVHCVEEVGFEVMGNSTF", "length": 415 }, "evidence": [ { "id": "R4GKR1", "url": "https://omabrowser.org/oma/group/R4GKR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01344-1", "protein_name": "Interleukin-5 receptor subunit alpha", "gene_name": "IL5RA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF", "length": 420 }, "evidence": [ { "id": "R4GKR1", "url": "https://omabrowser.org/oma/group/R4GKR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "interleukin-5 receptor activity", "id": "GO:0004914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004914", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "R4GKR1", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GKR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 424, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GKR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GKR1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR1" }, { "id": "PF09240", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Type I cytokine receptor cytokine-binding", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 239, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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] }, { "uniprot_canonical_ac": "Q9I8I2-1", "uniprot_ac": "Q9I8I2", "uniprot_id": "BOK_CHICK", "mass": { "chemical_mass": 23620.0, "monoisotopic_mass": 23620.0 }, "refseq": { "ac": "NP_990037", "name": "bcl-2-related ovarian killer protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" }, "gene_names": [ { "name": "BOK", "type": "recommended", "evidence": [ { "id": "Q9I8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ] }, { "name": "BOK", "type": "synonym", "evidence": [ { "id": "NP_990037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" } ] } ], "protein_names": [ { "name": "Bcl-2-related ovarian killer protein", "type": "recommended", "evidence": [ { "id": "Q9I8I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2/entry#names_and_taxonomy" } ] }, { "name": "BCL2-related ovarian killer", "type": "synonym", "evidence": [ { "id": "NP_990037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" } ] }, { "name": "BOK, BCL2 family apoptosis regulator", "type": "synonym", "evidence": [ { "id": "NP_990037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" } ] }, { "name": "bcl-2-related ovarian killer protein", "type": "synonym", "evidence": [ { "id": "NP_990037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01022682.1, ERR2365563.103739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037" } ] }, { "annotation": "May play a role in apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2#function" }, { "database": "UniProtKB", "id": "O35425", "url": "https://www.uniprot.org/uniprotkb/O35425#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BOK", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2", "locus": { "chromosome": "9", "start_pos": 4764405, "end_pos": 4744649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023473", "url": "https://www.ensembl.org/id/ENSGALG00010023473" } ] } } ], "crossref": [ { "id": "Q9I8I2", "url": "https://alphafold.ebi.ac.uk/entry/Q9I8I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06845", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06845", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395445", "url": "https://www.ncbi.nlm.nih.gov/gene/395445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "5WDD", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=5WDD&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR002475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMTKCVV", "url": "https://omabrowser.org/oma/group/DMTKCVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN00", "url": "https://www.orthodb.org/?gene=A0A8V0ZN00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN06", "url": "https://www.orthodb.org/?gene=A0A8V0ZN06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q9I8I2", "url": "https://www.orthodb.org/?gene=Q9I8I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11256:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11256:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00005wdd", "url": "https://www.rcsb.org/structure/pdb_00005wdd", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5WDD", "url": "https://www.rcsb.org/structure/5WDD", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9I8I2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9I8I2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990037", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990037", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9I8I2-1", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVLRRSSVFAAEVMEVFDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWADITKCVVSTDPSLRSHWLVAAVCSFGHFLKAIFFVLLPER", "length": 213, "header": "sp|Q9I8I2-1|BOK_CHICK Isoform 1 of Bcl-2-related ovarian killer protein OS=Gallus gallus OX=9031 GN=BOK PE=1 SV=1 CANONICAL=Q9I8I2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN00-1", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2/entry#A0A8V0ZN00-1", "sequence": { "sequence": "MEVLRRSSVFAAEVMEVFDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWLVAADGLHSPLMATGASPTVPVLEAPFPMGTRGGRSYDLKRNGKKRGGAALPHCMQSSFSLQTHIVSLLVSVFC", "length": 246, "header": "tr|A0A8V0ZN00-1|A0A8V0ZN00_CHICK Computationally mapped isoform of BOK, BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=BOK PE=3 SV=1 CANONICAL=Q9I8I2-1" }, "locus": { "chromosome": "9", "start_pos": 4763920, "end_pos": 4752237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057182.1", "url": "https://www.ensembl.org/id/ENSGALT00010057182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034776.1", "url": "https://www.ensembl.org/id/ENSGALP00010034776.1" } ] } }, { "isoform_ac": "A0A8V0ZN06-1", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2/entry#A0A8V0ZN06-1", "sequence": { "sequence": "MEVLRRSSVFAAEVMEVFDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWALQRDISQPCSQTKWLCAGAPFICCLTSLLLVCLGLASAFLLCTWPHHTPAWAAKRNLCAPGSAGRASAQQ", "length": 243, "header": "tr|A0A8V0ZN06-1|A0A8V0ZN06_CHICK Computationally mapped isoform of BOK, BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=BOK PE=3 SV=1 CANONICAL=Q9I8I2-1" }, "locus": { "chromosome": "9", "start_pos": 4761147, "end_pos": 4752237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057189.1", "url": "https://www.ensembl.org/id/ENSGALT00010057189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034781.1", "url": "https://www.ensembl.org/id/ENSGALP00010034781.1" } ] } }, { "isoform_ac": "Q9I8I2-1", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2/entry#Q9I8I2-1", "sequence": { "sequence": "MEVLRRSSVFAAEVMEVFDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWADITKCVVSTDPSLRSHWLVAAVCSFGHFLKAIFFVLLPER", "length": 213, "header": "sp|Q9I8I2-1|BOK_CHICK Isoform 1 of Bcl-2-related ovarian killer protein OS=Gallus gallus OX=9031 GN=BOK PE=1 SV=1 CANONICAL=Q9I8I2-1" }, "locus": { "chromosome": "9", "start_pos": 4763581, "end_pos": 4752237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057196.1", "url": "https://www.ensembl.org/id/ENSGALT00010057196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034787.1", "url": "https://www.ensembl.org/id/ENSGALP00010034787.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolutionarily conserved Bok proteins in the Bcl-2 family.", "journal": "FEBS Lett.", "date": "2000", "authors": "Zhang H, Holzgreve W, De Geyter C", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "reference": [ { "type": "PubMed", "id": "11034351", "url": "https://glygen.org/publication/PubMed/11034351" } ] } ], "pathway": [ { "id": "gga:395445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395445", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AST0-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "BOK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREFVHARLLRAGLAWNAPERAAPAPGGRLAEVCAVLLRLADELELIRPSVYRNVARQLNLSLQSETVVTDAFLAVAAQIFSAGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDLLKCVVSADPGRRSHWLVAAFCSFGRFLKAAFFLLLPER", "length": 213 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H4V6-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "Bok", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERTSPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAVFFLLLPER", "length": 213 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35425-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "Bok", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERASPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHIPLQSEPVVTDAFLAVAGHIFSAGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAAFFLLLPER", "length": 213 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DC66-1", "protein_name": "Bcl-2-related ovarian killer protein homolog A", "gene_name": "boka", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMLRRSSVFAAEVMEVFDRSPTDKELVSQSKVLCRDYIHSRLHRAGIGWSKPEHGSGGTLAEVSSVLLWLGDELEYLRPNVYRNVARQLNITIASENIVSDAFLAVAAEIFSTEYSRKGLEKHKGVTWGKIVSLYAVAGALAVDCVRNGHPAMVHTIVDCMGEFVRKSLASWLKKRGGWADITKCVVSTDPSFHSHWLVTAACACGHYLKAVVFYLLREK", "length": 221 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q792S6-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "Bok", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERASPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHIPLQSEPVVTDAFLAVAGHIFSAGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAAFFLLLPER", "length": 213 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UMX3-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "BOK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERAAPVPGRLAEVCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAVAGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAFFVLLPER", "length": 212 }, "evidence": [ { "id": "Q9I8I2", "url": "https://omabrowser.org/oma/group/Q9I8I2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "release of cytochrome c from mitochondria", "id": "GO:0001836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001836", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway in absence of ligand", "id": "GO:0097192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097192", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "positive regulation of PERK-mediated unfolded protein response", "id": "GO:1903899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903899", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "id": "GO:1901029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901029", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902237", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "negative regulation of necroptotic process", "id": "GO:0060546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060546", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "positive regulation of execution phase of apoptosis", "id": "GO:1900119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900119", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "id": "GO:1901030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901030", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial depolarization", "id": "GO:0051902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051902", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "cellular component disassembly involved in execution phase of apoptosis", "id": "GO:0006921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006921", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "regulation of chorionic trophoblast cell proliferation", "id": "GO:1901382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901382", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "regulation of granulosa cell apoptotic process", "id": "GO:1904708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904708", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q9I8I2", "url": "https://www.uniprot.org/uniprotkb/Q9I8I2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9I8I2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 213, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9I8I2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9I8I2" }, { "pdb_id": "5wdd", "pdb_chain": "a/b", "start_pos": 19, "end_pos": 181, "overlap": "1.0", "method": "X-Ray_Crystallography", "type": "experimental", "resolution": -1.0, "url": 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GKN9-1", "uniprot_ac": "R4GKN9", "uniprot_id": "R4GKN9_CHICK", "mass": { "chemical_mass": 25782.0, "monoisotopic_mass": 25782.0 }, "refseq": { "ac": "XP_426425", "name": "rho-related GTP-binding protein RhoV", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426425" }, "gene_names": [ { "name": "RHOV", "type": "recommended", "evidence": [ { "id": "R4GKN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ] }, { "name": "RHOV", "type": "synonym", "evidence": [ { "id": "XP_426425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426425" } ] } ], "protein_names": [ { "name": "Ras homolog family member V", "type": "synonym", "evidence": [ { "id": "R4GKN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKN9/entry#names_and_taxonomy" } ] }, { "name": "rho-related GTP-binding protein RhoV", "type": "synonym", "evidence": [ { "id": "XP_426425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426425" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426425.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426425" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RHOV", "url": "https://www.uniprot.org/uniprotkb/R4GKN9", "locus": { "chromosome": "5", "start_pos": 23801576, "end_pos": 23807964, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022246", "url": "https://www.ensembl.org/id/ENSGALG00010022246" } ] } } ], "crossref": [ { "id": "R4GKN9", "url": "https://alphafold.ebi.ac.uk/entry/R4GKN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028047", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028047", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428868", "url": "https://www.ncbi.nlm.nih.gov/gene/428868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428868", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428868", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPELGIK", "url": "https://omabrowser.org/oma/group/TPELGIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUZ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZUZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GKN9", "url": "https://www.orthodb.org/?gene=R4GKN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_426425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426425", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKN9-1", "url": "https://www.uniprot.org/uniprotkb/R4GKN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPQELLDYAPALRRHSPPRGSGPELGIKCVLVGDGAVGKTSLVVSYTTNGYPDEYQPTALDTFSVQVLVDGAPVRIQLWDTAGQEDFDCLRSLCYPDTDVFLVCFSVVNPSSFQNITEKWIPEIRTHNPRAPVLLVGTQADLRDDVNVLISLDRYHVKPVPRPQAEGLADKIRAEAYLECSALTQKNLKEVFDMAIVSGVEHKARQEKKMTAKGIKTLSKCRWKKFFCFV", "length": 231, "header": "tr|R4GKN9-1|R4GKN9_CHICK Isoform 1 of Ras homolog family member V OS=Gallus gallus OX=9031 GN=RHOV PE=3 SV=1 CANONICAL=R4GKN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZUZ3-1", "url": "https://www.uniprot.org/uniprotkb/R4GKN9/entry#A0A8V0ZUZ3-1", "sequence": { "sequence": "PRGSAWGGPGRVAPGPELGIKCVLVGDGAVGKTSLVVSYTTNGYPDEYQPTALDTFSVQVLVDGAPVRIQLWDTAGQEDFDCLRSLCYPDTDVFLVCFSVVNPSSFQNITEKWIPEIRTHNPRAPVLLVGTQADLRDDVNVLISLDRYHVKPVPRPQAEGLADKIRAEAYLECSALTQKNLKEVFDMAIVSGVEHKARQEKKMTAKGIKTLSKCRWKKFFCFV", "length": 223, "header": "tr|A0A8V0ZUZ3-1|R4GKN9_CHICK Computationally mapped isoform of Ras homolog family member V OS=Gallus gallus OX=9031 GN=RHOV PE=3 SV=1 CANONICAL=R4GKN9-1" }, "locus": { "chromosome": "5", "start_pos": 23807911, "end_pos": 23803826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054130.1", "url": "https://www.ensembl.org/id/ENSGALT00010054130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032661.1", "url": "https://www.ensembl.org/id/ENSGALP00010032661.1" } ] } }, { "isoform_ac": "R4GKN9-1", "url": "https://www.uniprot.org/uniprotkb/R4GKN9/entry#R4GKN9-1", "sequence": { "sequence": "MPPQELLDYAPALRRHSPPRGSGPELGIKCVLVGDGAVGKTSLVVSYTTNGYPDEYQPTALDTFSVQVLVDGAPVRIQLWDTAGQEDFDCLRSLCYPDTDVFLVCFSVVNPSSFQNITEKWIPEIRTHNPRAPVLLVGTQADLRDDVNVLISLDRYHVKPVPRPQAEGLADKIRAEAYLECSALTQKNLKEVFDMAIVSGVEHKARQEKKMTAKGIKTLSKCRWKKFFCFV", "length": 231, "header": "tr|R4GKN9-1|R4GKN9_CHICK Isoform 1 of Ras homolog family member V OS=Gallus gallus OX=9031 GN=RHOV PE=3 SV=1 CANONICAL=R4GKN9-1" }, "locus": { "chromosome": "5", "start_pos": 23807792, "end_pos": 23803826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054134.1", "url": "https://www.ensembl.org/id/ENSGALT00010054134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032666.1", "url": "https://www.ensembl.org/id/ENSGALP00010032666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428868", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428868", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SST5-1", "protein_name": "Ras homolog family member V", "gene_name": "RHOV", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPRELSEAESSPLRAPTPPPRRGSASPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIELDQGGREGPVPEPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIENKARLEKKLNAKGVRTLSRCRWKKFFCFV", "length": 236 }, "evidence": [ { "id": "R4GKN9", "url": "https://omabrowser.org/oma/group/R4GKN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q17QI8-1", "protein_name": "Rho-related GTP-binding protein RhoV", "gene_name": "Rhov", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPRELSEAESSPLRSPTPPPGRGSASPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDLDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "length": 236 }, "evidence": [ { "id": "R4GKN9", "url": "https://omabrowser.org/oma/group/R4GKN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VDU1-1", "protein_name": "Rho-related GTP-binding protein RhoV", "gene_name": "Rhov", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPRELSEAEPPPLPASTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "length": 236 }, "evidence": [ { "id": "R4GKN9", "url": "https://omabrowser.org/oma/group/R4GKN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96L33-1", "protein_name": "Rho-related GTP-binding protein RhoV", "gene_name": "RHOV", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "length": 236 }, "evidence": [ { "id": "R4GKN9", "url": "https://omabrowser.org/oma/group/R4GKN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "R4GKN9", "url": "https://www.uniprot.org/uniprotkb/R4GKN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GKN9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 231, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GKN9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GKN9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GI86-1", "uniprot_ac": "R4GI86", "uniprot_id": "R4GI86_CHICK", "mass": { "chemical_mass": 39899.0, "monoisotopic_mass": 39899.0 }, "refseq": { "ac": "XP_003641786", "name": "calcium-binding protein 39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641786" }, "gene_names": [ { "name": "CAB39", "type": "recommended", "evidence": [ { "id": "R4GI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ] }, { "name": "CAB39", "type": "synonym", "evidence": [ { "id": "XP_003641786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641786" } ] } ], "protein_names": [ { "name": "Calcium binding protein 39", "type": "synonym", "evidence": [ { "id": "R4GI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI86/entry#names_and_taxonomy" } ] }, { "name": "calcium-binding protein 39", "type": "synonym", "evidence": [ { "id": "XP_003641786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641786" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641786" } ] }, { "annotation": "Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A5K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K2#function" }, { "database": "UniProtKB", "id": "ARBA00025206", "url": "https://www.uniprot.org/uniprotkb/ARBA00025206#function" }, { "database": "UniProtKB", "id": "A0A8V1A5K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K8#function" }, { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAB39", "url": "https://www.uniprot.org/uniprotkb/R4GI86", "locus": { "chromosome": "9", "start_pos": 5076614, "end_pos": 5112143, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024970", "url": "https://www.ensembl.org/id/ENSGALG00010024970" } ] } } ], "crossref": [ { "id": "R4GI86", "url": "https://alphafold.ebi.ac.uk/entry/R4GI86", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027262", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424830", "url": "https://www.ncbi.nlm.nih.gov/gene/424830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424830", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYDHKES", "url": "https://omabrowser.org/oma/group/AYDHKES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5K2", "url": "https://www.orthodb.org/?gene=A0A8V1A5K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5K8", "url": "https://www.orthodb.org/?gene=A0A8V1A5K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GI86", "url": "https://www.orthodb.org/?gene=R4GI86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10182:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10182:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-380972", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI86-1", "url": "https://www.uniprot.org/uniprotkb/R4GI86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341, "header": "tr|R4GI86-1|R4GI86_CHICK Isoform 1 of Calcium binding protein 39 OS=Gallus gallus OX=9031 GN=CAB39 PE=1 SV=1 CANONICAL=R4GI86-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5K2-1", "url": "https://www.uniprot.org/uniprotkb/R4GI86/entry#A0A8V1A5K2-1", "sequence": { "sequence": "MFCWQAKTSVKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 314, "header": "tr|A0A8V1A5K2-1|R4GI86_CHICK Computationally mapped isoform of Calcium binding protein 39 OS=Gallus gallus OX=9031 GN=CAB39 PE=1 SV=1 CANONICAL=R4GI86-1" }, "locus": { "chromosome": "9", "start_pos": 5094073, "end_pos": 5079021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060971.1", "url": "https://www.ensembl.org/id/ENSGALT00010060971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037718.1", "url": "https://www.ensembl.org/id/ENSGALP00010037718.1" } ] } }, { "isoform_ac": "A0A8V1A5K8-1", "url": "https://www.uniprot.org/uniprotkb/R4GI86/entry#A0A8V1A5K8-1", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 338, "header": "tr|A0A8V1A5K8-1|R4GI86_CHICK Computationally mapped isoform of Calcium binding protein 39 OS=Gallus gallus OX=9031 GN=CAB39 PE=1 SV=1 CANONICAL=R4GI86-1" }, "locus": { "chromosome": "9", "start_pos": 5096024, "end_pos": 5079021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060977.1", "url": "https://www.ensembl.org/id/ENSGALT00010060977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037723.1", "url": "https://www.ensembl.org/id/ENSGALP00010037723.1" } ] } }, { "isoform_ac": "R4GI86-1", "url": "https://www.uniprot.org/uniprotkb/R4GI86/entry#R4GI86-1", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341, "header": "tr|R4GI86-1|R4GI86_CHICK Isoform 1 of Calcium binding protein 39 OS=Gallus gallus OX=9031 GN=CAB39 PE=1 SV=1 CANONICAL=R4GI86-1" }, "locus": { "chromosome": "9", "start_pos": 5096024, "end_pos": 5079021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060975.1", "url": "https://www.ensembl.org/id/ENSGALT00010060975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037721.1", "url": "https://www.ensembl.org/id/ENSGALP00010037721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424830", "resource": "KEGG Pathway" }, { "id": "R-GGA-380972", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380972", "resource": "Reactome", "description": "Energy dependent regulation of mTOR by LKB1-AMPK" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MYG4-1", "protein_name": "Calcium-binding protein 39", "gene_name": "Cab39", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "C7G028-1", "protein_name": "Mo25-like family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIFFNKKQKTPSELVKSIKESLASMDKSGPNSKSTEKASEEISKCLQEIKKILHGDSEHEPNQEVVAVLSNEICTSDLVQILIKDLNKLEFEAKKDVAQIFNILLRHKNGARSPIVEYIAKNPEILDSLVKGYEQQDIALNCGTMLRECIKHESLAKILIYSPNFWEFFEFVEVSNFDVASDTFATFKEILTKHKTLSAEFLEKNYDQVFEKYTTLLNSQNYVTRRQSIKVNNNSNNNNNNNNNNNNNNNNNNNNNAAILLGELLLDRSNFNIMPLYISSAANLKFMMNLLRDKSKSIQYEAFHVFKVFVANPNKTKPILEILTKNKEKLIAFLSQFHNDKEEDQFSDEKNFLVKQIQAIQG", "length": 363 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "D3ZJ77-1", "protein_name": "Calcium binding protein 39", "gene_name": "Cab39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRAAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SMX5-1", "protein_name": "Calcium binding protein 39", "gene_name": "CAB39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPFPFGKSHKSPADIVRNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32464-1", "protein_name": "Protein HYM1", "gene_name": "HYM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDSQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR", "length": 399 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P91891-1", "protein_name": "Protein Mo25", "gene_name": "Mo25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPLFGKSQKSPVELVKSLKEAINALEAGDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPADYVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFTLMAGYEDAHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELLTRHKLLCAEFLDANYDKFFSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENLKLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFNDEKAYLIKQIKELKPLPEA", "length": 339 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q06138-1", "protein_name": "Calcium-binding protein 39", "gene_name": "Cab39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLGTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQTKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRAAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q29RI6-1", "protein_name": "Calcium-binding protein 39", "gene_name": "CAB39", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y376-1", "protein_name": "Calcium-binding protein 39", "gene_name": "CAB39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA", "length": 341 }, "evidence": [ { "id": "R4GI86", "url": "https://omabrowser.org/oma/group/R4GI86/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular hypotonic response", "id": "GO:0071476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071476", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" }, { "name": "negative regulation of potassium ion transmembrane transport", "id": "GO:1901380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901380", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "serine/threonine protein kinase complex", "id": "GO:1902554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902554", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" }, { "name": "protein serine/threonine kinase binding", "id": "GO:0120283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120283", "evidence": [ { "database": "UniProtKB", "id": "R4GI86", "url": "https://www.uniprot.org/uniprotkb/R4GI86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GI86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 341, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GI86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GI86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 298, "end_pos": 300 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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NCBI review. The reference sequence was derived from JAENSK010000356.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989729" } ] }, { "annotation": "Probable component of the mechanotransducer (MET) non-specific cation channel complex.", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZL8", "url": "https://www.uniprot.org/uniprotkb/Q7ZZL8#function" }, { "database": "UniProtKB", "id": "Q4KL25", "url": "https://www.uniprot.org/uniprotkb/Q4KL25#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q7ZZL8", "url": "https://www.uniprot.org/uniprotkb/Q7ZZL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LHFPL5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZL8", "locus": { "chromosome": "26", 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gallus OX=9031 GN=LHFPL5 PE=2 SV=1 CANONICAL=Q7ZZL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A977-1", "url": "https://www.uniprot.org/uniprotkb/Q7ZZL8/entry#A0A8V1A977-1", "sequence": { "sequence": "MPKLLPAQEAARIYHTNYVRNARAMGVLWALFTLCFSILMVVTFIQPYWIGDSIDTPQAGYFGLFSYCIGNALTGELICKGSPLDFGTIPSSAFKTAMFFVGISTFLIIGSILCFSLFFFCNAATVYKVCAWMQLAAATGLMIGCLIYPDGWDSSEVKRMCGDKTDKYTLGACTVRWAYILCIIGILDALILSFLAFVLGNRQDNLLPSDFKVESKGESSRLGVEVAGGGGGGGGGGGGGGGGGLSASNGVGVGGSEPFGKRSWKAHLHLH", "length": 271, "header": "tr|A0A8V1A977-1|LHPL5_CHICK Computationally mapped isoform of LHFPL tetraspan subfamily member 5 protein OS=Gallus gallus OX=9031 GN=LHFPL5 PE=2 SV=1 CANONICAL=Q7ZZL8-1" }, "locus": { "chromosome": "26", "start_pos": 142368, "end_pos": 139968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065351.1", "url": "https://www.ensembl.org/id/ENSGALT00010065351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039778.1", "url": "https://www.ensembl.org/id/ENSGALP00010039778.1" } ] } }, { "isoform_ac": "Q7ZZL8-1", "url": "https://www.uniprot.org/uniprotkb/Q7ZZL8/entry#Q7ZZL8-1", "sequence": { "sequence": "MPKLLPAQEAARIYHTNYVRNARAMGVLWALFTLCFSILMVVTFIQPYWIGDSIDTPQAGYFGLFSYCIGNALTGELICKGSPLDFGTIPSSAFKTAMFFVGISTFLIIGSILCFSLFFFCNAATVYKVCAWMQLAAATGLMIGCLIYPDGWDSSEVKRMCGDKTDKYTLGACTVRWAYILCIIGILDALILSFLAFVLGNRQDNLLPSDFKVESKEEGNE", "length": 221, "header": "sp|Q7ZZL8-1|LHPL5_CHICK Isoform 1 of LHFPL tetraspan subfamily member 5 protein OS=Gallus gallus OX=9031 GN=LHFPL5 PE=2 SV=1 CANONICAL=Q7ZZL8-1" }, "locus": { "chromosome": "26", "start_pos": 142438, "end_pos": 139968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010065352.1", "url": "https://www.ensembl.org/id/ENSGALT00010065352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039779.1", "url": "https://www.ensembl.org/id/ENSGALP00010039779.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:378916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378916", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5PPI7-1", "protein_name": "LHFPL tetraspan subfamily member 5 protein", "gene_name": "Lhfpl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKLLPAQEAAKIYHTNYVRNSRAVGVMWGTLTICFSVLVMALFIQPYWIGDSVSTPQAGYFGLFSYCVGNVLSSELICKGGPLDFSSIPSRAFKTAMFFVALAMFLIIGSIICFSLFFVCNTATVYKICAWMQLAAATGLMIGCLVYPDGWDSSEVRRMCGEQTGKYTLGHCTIRWAFMLAILSIGDALILSFLAFVLGYRQDKLLPDDYKADGNEEV", "length": 219 }, "evidence": [ { "id": "Q7ZZL8", "url": "https://omabrowser.org/oma/group/Q7ZZL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJG3-1", "uniprot_ac": "R4GJG3", "uniprot_id": "R4GJG3_CHICK", "mass": { "chemical_mass": 25889.0, "monoisotopic_mass": 25889.0 }, "refseq": { "ac": "XP_015150937", "name": "MIF4G domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150937" }, "gene_names": [ { "name": "MIF4GD", "type": "recommended", "evidence": [ { "id": "R4GJG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ] }, { "name": "MIF4GD", "type": "synonym", "evidence": [ { "id": "XP_015150937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150937" } ] } ], "protein_names": [ { "name": "MIF4G domain containing", "type": "synonym", "evidence": [ { "id": "R4GJG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJG3/entry#names_and_taxonomy" } ] }, { "name": "MIF4G domain-containing protein", "type": "synonym", "evidence": [ { "id": "XP_015150937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150937" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150937" } ] }, { "annotation": "Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV3#function" }, { "database": "UniProtKB", "id": "ARBA00037643", "url": "https://www.uniprot.org/uniprotkb/ARBA00037643#function" }, { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIF4GD", "url": "https://www.uniprot.org/uniprotkb/R4GJG3", "locus": { "chromosome": "18", "start_pos": 11356334, "end_pos": 11365267, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029703", "url": "https://www.ensembl.org/id/ENSGALG00010029703" } ] } } ], "crossref": [ { "id": "R4GJG3", "url": "https://alphafold.ebi.ac.uk/entry/R4GJG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026715", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100858848", "url": "https://www.ncbi.nlm.nih.gov/gene/100858848", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858848", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858848", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCCSCTG", "url": "https://omabrowser.org/oma/group/PCCSCTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AES5", "url": "https://www.orthodb.org/?gene=A0A8V1AES5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APV3", "url": "https://www.orthodb.org/?gene=A0A8V1APV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJG3", "url": "https://www.orthodb.org/?gene=R4GJG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23254:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23254:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AES5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AES5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AES5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJG3-1", "url": "https://www.uniprot.org/uniprotkb/R4GJG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGETSKEEYKIQSFDIETQKLLKTALKDPSNVDLDKVANIIVDQSLKDCVFSKEAGRICYTIIQAESKQGGQSIFRRSLLNRLQQEYKDREDLRNRSLQAWICYVTFICNIFDYLKVNNMPMLALVNPVYDCLFRLAQHDSLQKEEEVDCLVLQLHRVGEQLEKMNSQRMDELFSLLRDGFLLQEGLSSLSQLLLLEIIEFRAADWKMTDAAQKYYYSEVTD", "length": 222, "header": "tr|R4GJG3-1|R4GJG3_CHICK Isoform 1 of MIF4G domain containing OS=Gallus gallus OX=9031 GN=MIF4GD PE=3 SV=2 CANONICAL=R4GJG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AES5-1", "url": "https://www.uniprot.org/uniprotkb/R4GJG3/entry#A0A8V1AES5-1", "sequence": { "sequence": "MGETSKEEYKIQSFDIETQKLLKTALKDPSNVDLDKVANIIVDQSLKDCVFSKEAGRICYTIIQVNNMPMLALVNPVYDCLFRLAQHDSLQKEEEVDCLVLQLHRVGEQLEKMNSQRMDELFSLLRDGFLLQEGLSSLSQLLLLEIIEFRAADWKMTDAAQKYYYSEVTD", "length": 170, "header": "tr|A0A8V1AES5-1|R4GJG3_CHICK Computationally mapped isoform of MIF4G domain containing OS=Gallus gallus OX=9031 GN=MIF4GD PE=3 SV=1 CANONICAL=R4GJG3-1" }, "locus": { "chromosome": "18", "start_pos": 11362364, "end_pos": 11358736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071843.1", "url": "https://www.ensembl.org/id/ENSGALT00010071843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044533.1", "url": "https://www.ensembl.org/id/ENSGALP00010044533.1" } ] } }, { "isoform_ac": "A0A8V1APV3-1", "url": "https://www.uniprot.org/uniprotkb/R4GJG3/entry#A0A8V1APV3-1", "sequence": { "sequence": "MGIKHDSHPELGETPRGRDPSNVDLDKVANIIVDQSLKDCVFSKEAGRICYTIIQAESKQGGQSIFRRSLLNRLQQEYKDREDLRNRSLQAWICYVTFICNIFDYLKVNNMPMLALVNPVYDCLFRLAQHDSLQKEEEVDCLVLQLHRVGEQLEKMNSQRMDELFSLLRDGFLLQEGLSSLSQLLLLEIIEFRAADWKMTDAAQKYYYSEVTD", "length": 213, "header": "tr|A0A8V1APV3-1|R4GJG3_CHICK Computationally mapped isoform of MIF4G domain containing OS=Gallus gallus OX=9031 GN=MIF4GD PE=3 SV=1 CANONICAL=R4GJG3-1" }, "locus": { "chromosome": "18", "start_pos": 11364697, "end_pos": 11358736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071844.1", "url": "https://www.ensembl.org/id/ENSGALT00010071844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044534.1", "url": "https://www.ensembl.org/id/ENSGALP00010044534.1" } ] } }, { "isoform_ac": "R4GJG3-1", "url": "https://www.uniprot.org/uniprotkb/R4GJG3/entry#R4GJG3-1", "sequence": { "sequence": "MGETSKEEYKIQSFDIETQKLLKTALKDPSNVDLDKVANIIVDQSLKDCVFSKEAGRICYTIIQAESKQGGQSIFRRSLLNRLQQEYKDREDLRNRSLQAWICYVTFICNIFDYLKVNNMPMLALVNPVYDCLFRLAQHDSLQKEEEVDCLVLQLHRVGEQLEKMNSQRMDELFSLLRDGFLLQEGLSSLSQLLLLEIIEFRAADWKMTDAAQKYYYSEVTD", "length": 222, "header": "tr|R4GJG3-1|R4GJG3_CHICK Isoform 1 of MIF4G domain containing OS=Gallus gallus OX=9031 GN=MIF4GD PE=3 SV=2 CANONICAL=R4GJG3-1" }, "locus": { "chromosome": "18", "start_pos": 11362364, "end_pos": 11358736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071845.1", "url": "https://www.ensembl.org/id/ENSGALT00010071845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044535.1", "url": "https://www.ensembl.org/id/ENSGALP00010044535.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858848", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZK28-1", "protein_name": "MIF4G domain-containing protein", "gene_name": "MIF4GD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVMGEPGREEYRIQSFDAESQQLLKTALKDPGAVDLEKVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQQEYQAREQLRARSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFRLAQPDSLSKEEEVDCLVLQLHRVGEQLEKMNRQRMDELFVLIRDGFLLPTGLSSLAQLLLLETIEFRAAGWKTTPAAHKYYYSELSD", "length": 224 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A9UHW6-1", "protein_name": "MIF4G domain-containing protein", "gene_name": "MIF4GD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEPSREEYKIQSFDAETQQLLKTALKDPGAVDLEKVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQQEYQAREQLRARSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFRLAQPDSLSKEEEVDCLVLQLHRVGEQLEKMNGQRMDELFVLIRDGFLLPTGLSSLAQLLLLEIIEFRAAGWKTTPAAHKYYYSEVSD", "length": 222 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3GTE7-1", "protein_name": "MIF4G domain-containing protein", "gene_name": "Mif4gd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGEASRDEYKIQSFDAETQQLLKTALKDPGTVDLEKVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLDRLQREYQAREQLRARSLQSWVCYVTFICNIFDYLRVNNMPMLALVNPVYDCLFQLAQPESLSREEEVDCLVLQLHRVGEQLEKMNGQRMDELFVLIRDGFLLPLGLSSLGRLLLLEMIEFRAAGWKTTPAAHKYYYSEVSD", "length": 222 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UBZ5-1", "protein_name": "MIF4G domain-containing protein", "gene_name": "Mif4gd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEASRDDYKIQSFDAETQQLLKTALKDPGAVDLERVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQKEYDAREQLRACSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFQLAQPESLSREEEVDCLVLQLHRVGEQLEKMNGQRMDELFILIRDGFLLPTDLSSLARLLLLEMIEFRAAGWKTTPAAHKYYYSEVSD", "length": 222 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZC21-1", "protein_name": "MIF4G domain-containing protein", "gene_name": "MIF4GD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGEPSKEEYKIQCFDAETQQLLKTALKDPGAVDLEKVANVIVDHSLQDSVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQQEYQTREQLRARSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFRLAQPDSLSKEEEVDCLVLQLHRVGEQLEKMNGQRMDELFVLIRDGFLLPAGLSSLAQLLLLEIIEFRAAGWKTTPAAHKYYYSEVSD", "length": 222 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5EAQ1-1", "protein_name": "MIF4G domain-containing protein B", "gene_name": "mif4gdb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENSSKEDYKIQSFDLETQKLLKTALKDPGSVDLEKVSSVIVDQSLKDQVFSREAGRICYTIVQAEAKQTNGSVFRRNLLNRLQQEFKAREETRKRSTQEWVCLVSFICNIFDYLKVNNMPMVALVHPVYDCLFRLAQSDALKNEEEVDCLVLQLHRIGDQLEKMNVQLMDELFNLLRDGFLLQEDLSSMGRLLLLEILEFRAGGWKLSDTAQKYYYSEVTD", "length": 222 }, "evidence": [ { "id": "R4GJG3", "url": "https://omabrowser.org/oma/group/R4GJG3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" }, { "name": "histone mRNA stem-loop binding complex", "id": "GO:0062073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062073", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" }, { "name": "translation activator activity", "id": "GO:0008494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008494", "evidence": [ { "database": "UniProtKB", "id": "R4GJG3", "url": "https://www.uniprot.org/uniprotkb/R4GJG3" } ], "pmid": "" } ] }, { "name": "Biological 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"https://www.ncbi.nlm.nih.gov/protein/NP_001039300" } ] }, { "name": "C-C chemokine receptor type 2", "type": "synonym", "evidence": [ { "id": "NP_001039300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039300" } ] }, { "name": "C-C motif chemokine receptor 2", "type": "synonym", "evidence": [ { "id": "Q702H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q702H7/entry#names_and_taxonomy" } ] }, { "name": "chemokine (C-C motif) receptor 2", "type": "synonym", "evidence": [ { "id": "NP_001039300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039300" } ] } ], "function": [ { "annotation": "VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ627213.1. 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] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420696", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHIALGC", "url": "https://omabrowser.org/oma/group/YHIALGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q702H7", "url": "https://www.orthodb.org/?gene=Q702H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489:SF686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489:SF686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1461957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1461957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380108", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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chemokine receptor 2 OS=Gallus gallus OX=9031 GN=CCR2 PE=3 SV=1 CANONICAL=Q702H7-1" }, "isoforms": [ { "isoform_ac": "Q702H7-1", "url": "https://www.uniprot.org/uniprotkb/Q702H7/entry#Q702H7-1", "sequence": { "sequence": "MENYTDLGDMPTTTFDYGDTAPCMGTEEKHFAANFLPPLYSLVVIFGFIGNILVVLILVKYKKLKSMTDIYLLNLAISDLLFVFSLPFWAYYAAHDWIFGDALCRILSGVYLLGFYSGIFFIILLTIDRYLAIVHAVFALKARTVTYGILTSIVTWAVALFASVPGIVFHKTQQENTQCTCSFHYPSDALINWQHSYILKMNILGLIIPMIIMIFCYSQILRTLFGCRNEKKQKAVRLIFVIMIFYFIFWTPFHVASFVHTFQTSFFSPDCDSQSRLEKTIQVTETISMVHCCINPVIYAFVGEKFRKYLHMFFRKHVATHLCKKCPSLYREKLERVSSTFTASTAEHDISTGL", "length": 354, "header": "tr|Q702H7-1|Q702H7_CHICK Isoform 1 of C-C motif chemokine receptor 2 OS=Gallus gallus OX=9031 GN=CCR2 PE=3 SV=1 CANONICAL=Q702H7-1" }, "locus": { "chromosome": "2", "start_pos": 42604396, "end_pos": 42603335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041859.1", "url": "https://www.ensembl.org/id/ENSGALT00010041859.1" }, { "database": "Ensembl 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The reference sequence was derived from JAENSK010000237.1. On Oct 5, 2021 this sequence version replaced NP_989716.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989716" } ] }, { "annotation": "Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G protein (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q7SZC6", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q7SZC6", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS4", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6", "locus": { "chromosome": "8", "start_pos": 3692084, "end_pos": 3591779, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012749", "url": "https://www.ensembl.org/id/ENSGALG00010012749" } ] } } ], "crossref": [ { "id": "Q7SZC6", "url": "https://alphafold.ebi.ac.uk/entry/Q7SZC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "378901", "url": "https://www.ncbi.nlm.nih.gov/gene/378901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:378901", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q7SZC6", "url": "https://www.orthodb.org/?gene=Q7SZC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845:SF184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845:SF184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q7SZC6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q7SZC6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q7SZC6", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7SZC6-1", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCKGLAALPATCLKSAKDMKHRLGVLLQKSDSCDYGSSQGKKEKVSSSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 208, "header": "sp|Q7SZC6-1|RGS4_CHICK Isoform 1 of Regulator of G protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=2 SV=1 CANONICAL=Q7SZC6-1" }, "isoforms": [ { "isoform_ac": "Q7SZC6-1", "url": "https://www.uniprot.org/uniprotkb/Q7SZC6/entry#Q7SZC6-1", "sequence": { "sequence": "MCKGLAALPATCLKSAKDMKHRLGVLLQKSDSCDYGSSQGKKEKVSSSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 208, "header": "sp|Q7SZC6-1|RGS4_CHICK Isoform 1 of Regulator of G protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=2 SV=1 CANONICAL=Q7SZC6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b.", "journal": "J. 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The reference sequence was derived from JAENSK010000037.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989789" } ] }, { "annotation": "May play a pivotal role in the formation and/or maintenance of lipid rafts. 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"https://alphafold.ebi.ac.uk/entry/Q7SZI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "395109", "url": "https://www.ncbi.nlm.nih.gov/gene/395109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395109", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPEDHAS", "url": "https://omabrowser.org/oma/group/CPEDHAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q7SZI5", "url": "https://www.orthodb.org/?gene=Q7SZI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q7SZI5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q7SZI5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q7SZI5", "url": "https://www.uniprot.org/uniprotkb/Q7SZI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7SZI5-1", "url": "https://www.uniprot.org/uniprotkb/Q7SZI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGLNKLEKHDEKRPGNIYSTLKRPQVETKIDVSYEYRFLDFTTLNDAELPGSSAIKLSSLRDLPAQLQELYQQGFVLAAVHPFVQPTDEKEKTPQEQIFRAVLIKKTERSPKGGIHSEGYILEVECCSSVNQLSDKKEIPDFIKKIQDAASQGLKFVGIIPQYHSQKNCLVSSSLTPASNNSVQSRDNKNVSNCPEDHASLDGEKIDGINGCSTPAPGEENADQCATSREGRKGEGQAAEEPDCKSAKGSKEQHEHPGGREAPDTQNGVAENETPARCSKPLTDKTEIFTLFNKPKTPQRCSQYYTVTIPMRISRNGQTVNSLEANWLEHMTDHFRKGGSLVNAIFSLGMVNDSLHGTMDGVFLFEDVAVEDNKTTQGYDAIVVEQWTVLKGVEVQTDYVPLLNSLAIYGWQLTCVLPTPIVKTNREGNLSTKQIVFLQRPSLPQKAKKKESKFHWRFSKEDMHNKPMKKSRKTKLSSGEKQTAEKQEFEVTENTRNLAAQLSAASGPGPEQQLDSVINLGNETAGADSRGTLHDGVSEGTCPASADAGDTGGSEVQACPNQSAPNCCEEQEAAGQDCALGPDSCQGIDGAAADVEPSCE", "length": 602, "header": "sp|Q7SZI5-1|RFTN1_CHICK Isoform 1 of Raftlin OS=Gallus gallus OX=9031 GN=RFTN1 PE=2 SV=3 CANONICAL=Q7SZI5-1" }, "isoforms": [ { "isoform_ac": "Q7SZI5-1", "url": "https://www.uniprot.org/uniprotkb/Q7SZI5/entry#Q7SZI5-1", "sequence": { "sequence": "MGCGLNKLEKHDEKRPGNIYSTLKRPQVETKIDVSYEYRFLDFTTLNDAELPGSSAIKLSSLRDLPAQLQELYQQGFVLAAVHPFVQPTDEKEKTPQEQIFRAVLIKKTERSPKGGIHSEGYILEVECCSSVNQLSDKKEIPDFIKKIQDAASQGLKFVGIIPQYHSQKNCLVSSSLTPASNNSVQSRDNKNVSNCPEDHASLDGEKIDGINGCSTPAPGEENADQCATSREGRKGEGQAAEEPDCKSAKGSKEQHEHPGGREAPDTQNGVAENETPARCSKPLTDKTEIFTLFNKPKTPQRCSQYYTVTIPMRISRNGQTVNSLEANWLEHMTDHFRKGGSLVNAIFSLGMVNDSLHGTMDGVFLFEDVAVEDNKTTQGYDAIVVEQWTVLKGVEVQTDYVPLLNSLAIYGWQLTCVLPTPIVKTNREGNLSTKQIVFLQRPSLPQKAKKKESKFHWRFSKEDMHNKPMKKSRKTKLSSGEKQTAEKQEFEVTENTRNLAAQLSAASGPGPEQQLDSVINLGNETAGADSRGTLHDGVSEGTCPASADAGDTGGSEVQACPNQSAPNCCEEQEAAGQDCALGPDSCQGIDGAAADVEPSCE", "length": 602, "header": "sp|Q7SZI5-1|RFTN1_CHICK Isoform 1 of Raftlin OS=Gallus gallus OX=9031 GN=RFTN1 PE=2 SV=3 CANONICAL=Q7SZI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transduction.", "journal": "The EMBO journal", "date": "2003", "authors": "Saeki K, Miura Y, Aki D, Kurosaki T, Yoshimura A", "evidence": [ { "database": "UniProtKB", "id": "Q7SZI5", "url": "https://www.uniprot.org/uniprotkb/Q7SZI5" } ], "reference": [ { "type": "PubMed", "id": "12805216", "url": "https://glygen.org/publication/PubMed/12805216" } ] } ], "pathway": [ { "id": "gga:395109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395109", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M184-1", "protein_name": "Raftlin lipid raft linker 1", "gene_name": "Rftn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSRDLTLCETAVEMGCSLNKLEKREEKRPGNIYSTLKRPQVETKIDVTYEYCFLEFTTLTAAELPRSSATRLASLRDLPDQLLELYQQGFSLAALHPFVQPTRRQEKIPLEHIFRAILVKKTSRSQKAELPNEGYILELDHCSSLEHLADQKLVPEFIKKVQEAASRGLKFVSVVPQYQTSVSSAGSTRFLPVTNSDEGARDGKNTFGDRPSLESDTPKAADVDDATAGVNQRPEPNPGSAGEAPGAQQPGIPSPSEENEAVEFPLRGLRPALGGLEGDPSNGPEELPSRKMEIFAFFNRPRSQQKCLQYYPVTIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAVFQLGMANDSFYGLTDGVFIFEAVSTEDSKTTQGYDAIVVEQWTVLEGTEVQTDYMPLLNSLAAYGWQLTCVLPTPILKTNREGNVCTKQIVFLQRPCLPQKTKKRESKFQWRFSRNDIHSRQTRKSKGKPSAGDKQQAEENEKNLDDQFSRAGDAGNCVLGAQQWGRASEVREQRPGSAAVQNGPAGHNRDSVTLRHSNPRAEAELVPGPAPTEAN", "length": 568 }, "evidence": [ { "id": "Q7SZI5", "url": "https://omabrowser.org/oma/group/Q7SZI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H9Y1-1", "protein_name": "Raftlin", "gene_name": "Rftn1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCSLNKLEKHEEKRPGNIYSTLKRPQVETKIDVTYEYRFLEFTTLTAAELPRTSAVRLASLQDLPAQLLELYQQGFSLAALHPFVQPVNRQEKIFLEHIFRAILVKKTNRSQKTELHNEGYILELDDCSSLEHLAAQKLVPEFIKKVQEAASRGLKFVCVVPQYQSSVNSAGSSRSVPVANRVTDARDVKHHFGDHASLENDSPKAADVDTAIVGVNLTTLGCEPSPGSTAEVQSTQQPGIPTPSEEAEAGEFPLRESSPTLDGPEGDPSNGHEELLSRKMEIFAFFNRPKSQQKCRQYYPITIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAIFHLAMANDSFYGLTDGVFIFEAVSPEDNKTTQGYDAIVVEQWTVLEGAEVQTDYIPLLNSLAAYGWQLTCVLPTPILKTSREGNVSTKQIVFLQRPCLPQKTKKRESKFQWRFSREETQSRQTRKSKGKRSTRDKQQAEENEKNLEDQFPKAGDVGNCVLGTQQWGRASEVREQRQSLGAVQNGPAGHNRDSVAPRHSNPRVEDGLALGAAPAEAN", "length": 557 }, "evidence": [ { "id": "Q7SZI5", "url": "https://omabrowser.org/oma/group/Q7SZI5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q14699-1", "protein_name": "Raftlin", "gene_name": "RFTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLSAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILELDCCSSLDHPTDQKLIPEFIKKIQEAASQGLKFVGVIPQYHSSVNSAGSSAPVSTANSTEDARDAKNARGDHASLENEKPGTGDVCSAPAGRNQSPEPSSGPRGEVPLAKQPSSPSGEGDGGELSPQGVSKTLDGPESNPLEVHEEPLSGKMEIFTLFNKPKSHQKCRQYYPVTIPLHVSKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGIVNDSLHGLTDGVFIFEAVSTEDSKTIQGYDAIVVEQWTVLEGVEVQTDYVPLLNSLAAYGWQLTCVLPTPVVKTTSEGSVSTKQIVFLQRPCLPQKIKKKESKFQWRFSREEMHNRQMRKSKGKLSARDKQQAEENEKNLEDQSSKAGDMGNCVSGQQQEGGVSEEMKGPVQEDKGEQLSPGGLLCGVGVEGEAVQNGPASHSRALVGICTGHSNPGEDARDGDAEEVRELGTVEEN", "length": 578 }, "evidence": [ { "id": "Q7SZI5", "url": "https://omabrowser.org/oma/group/Q7SZI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SZI5", "url": "https://www.uniprot.org/uniprotkb/Q7SZI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q7SZI5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 602, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q7SZI5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q7SZI5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 563, "end_pos": 565 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q7ZT27-1", "uniprot_ac": "Q7ZT27", "uniprot_id": "Q7ZT27_CHICK", "mass": { "chemical_mass": 14505.0, "monoisotopic_mass": 14505.0 }, "refseq": { "ac": "NP_989764", "name": "cyclin-dependent kinase 4 inhibitor B", "summary": "This gene encodes a protein similar to one of two mammalian cyclin-dependent kinase inhibitor proteins which regulate the activity of cyclin-dependent protein kinases CDK4 and CDK6 which further cell cycle progression through G1. Expression of this protein in human keratinocytes is induced by TGF-beta, a cytokine that inhibits cell growth through arrest in the G1 phase of the cell cycle. There is evidence that the encoded protein is functionally equivalent to mammalian p16INK4a, a protein from a similar but distinct mammalian gene. [provided by RefSeq, Dec 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" }, "gene_names": [ { "name": "CDKN2B", "type": "recommended", "evidence": [ { "id": "Q7ZT27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27" } ] }, { "name": "CDKN2A", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "CDKN2B", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase 4 inhibitor D", "type": "recommended", "evidence": [ { "id": "Q7ZT27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 4 inhibitor B", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "cyclin-dependent kinase inhibitor 2B (melanoma, p16, inhibits CDK4)", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "p15INK4b tumor suppressor", "type": "synonym", "evidence": [ { "id": "NP_989764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "name": "p19-INK4d", "type": "synonym", "evidence": [ { "id": "Q7ZT27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY138247.1, AM065603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JAENSK010000209.1. This gene encodes a protein similar to one of two mammalian cyclin-dependent kinase inhibitor proteins which regulate the activity of cyclin-dependent protein kinases CDK4 and CDK6 which further cell cycle progression through G1. Expression of this protein in human keratinocytes is induced by TGF-beta, a cytokine that inhibits cell growth through arrest in the G1 phase of the cell cycle. There is evidence that the encoded protein is functionally equivalent to mammalian p16INK4a, a protein from a similar but distinct mammalian gene. [provided by RefSeq, Dec 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ] }, { "annotation": "Interacts strongly with CDK4 and CDK6 and inhibits them.", "evidence": [ { "database": "UniProtKB", "id": "Q7ZT27", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27#function" }, { "database": "UniProtKB", "id": "ARBA00056064", "url": "https://www.uniprot.org/uniprotkb/ARBA00056064#function" } ] }, { "annotation": "The INK4b transcript is expressed in the roof-plate of the developing hind-brain, consistent with a role in limiting cell proliferation.", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" }, { "database": "PubMed", "id": "16720639", "url": "https://glygen.org/publication/PubMed/16720639" } ] }, { "annotation": "The cell cycle-related gene CDKN2B showed higher expression in the cultured chicken embryonic fibroblast cells than that of cultured chicken primordial germ cells.", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" }, { "database": "PubMed", "id": "23155027", "url": "https://glygen.org/publication/PubMed/23155027" } ] }, { "annotation": "The study was aimed at identifying the methylation of the CDKN2B gene situated at locus bar in Polbar chickens on the 6th and 18th day of embryonic development using the methylation-specific PCR method.", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" }, { "database": "PubMed", "id": "24279164", "url": "https://glygen.org/publication/PubMed/24279164" } ] }, { "annotation": "This novel finding provides the first evidence that the tumour suppressor locus CDKN2A can affect pigmentation phenotypes and sheds new light on the functional significance of this gene.", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" }, { "database": "PubMed", "id": "20374521", "url": "https://glygen.org/publication/PubMed/20374521" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q7ZT27", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDKN2B", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27", "locus": { "chromosome": "Z", "start_pos": 83341829, "end_pos": 83345255, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001144", "url": "https://www.ensembl.org/id/ENSGALG00010001144" } ] } } ], "crossref": [ { "id": "ENSGALG00000026137", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026137", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395076", "url": "https://www.ncbi.nlm.nih.gov/gene/395076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395076", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SALQVMM", "url": "https://omabrowser.org/oma/group/SALQVMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q7ZT27", "url": "https://www.orthodb.org/?gene=Q7ZT27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { 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}, "isoforms": [ { "isoform_ac": "Q7ZT27-1", "url": "https://www.uniprot.org/uniprotkb/Q7ZT27/entry#Q7ZT27-1", "sequence": { "sequence": "MAQRAASTAADELANAAARGDLLRVKELLDGAADPNAVNSFGRTPIQVMMLGSPRVAELLLQRGADPNRPDPRTGCRPAHDAARAGFLDTLAALHRAGARLDLPDGRGRLPIDVAAGGPHGPVGCYLRRLPALPRAPLP", "length": 139, "header": "tr|Q7ZT27-1|Q7ZT27_CHICK Isoform 1 of Cyclin-dependent kinase 4 inhibitor D OS=Gallus gallus OX=9031 GN=CDKN2B PE=3 SV=1 CANONICAL=Q7ZT27-1" }, "locus": { "chromosome": "Z", "start_pos": 83345052, "end_pos": 83343122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002602.1", "url": "https://www.ensembl.org/id/ENSGALT00010002602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001152.1", "url": "https://www.ensembl.org/id/ENSGALP00010001152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Upregulation of chicken p15INK4b at senescence and in the developing brain.", "journal": "Journal of cell science", "date": "2006-06-15", "authors": "Kim Soo-Hyun, Rowe Janice, Fujii Hideta, Jones Rebecca, Schmierer Bernhard, Kong Byung-Whi, Kuchler Karl, Foster Douglas, Ish-Horowicz David, Peters Gordon", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ], "reference": [ { "type": "PubMed", "id": "16720639", "url": "https://glygen.org/publication/PubMed/16720639" } ] }, { "title": "Sex-linked barring in chickens is controlled by the CDKN2A /B tumour suppressor locus.", "journal": "Pigment cell & melanoma research", "date": "2010-08", "authors": "Hellstr\u00f6m Anders R, Sundstr\u00f6m Elisabeth, Gunnarsson Ulrika, Bed'Hom Bertrand, Tixier-Boichard Michele, Honaker Christa F, Sahlqvist Anna-Stina, Jensen Per, K\u00e4mpe Olle, Siegel Paul B, Kerje Susanne, Andersson Leif", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ], "reference": [ { "type": "PubMed", "id": "20374521", "url": "https://glygen.org/publication/PubMed/20374521" } ] }, { "title": "Gene pathways and cell cycle-related genes in cultured avian primordial germ cells.", "journal": "Poultry science", "date": "2012-12", "authors": "Rengaraj D, Lee B R, Choi J W, Lee S I, Seo H W, Kim T H, Choi H J, Song G, Han J Y", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ], "reference": [ { "type": "PubMed", "id": "23155027", "url": "https://glygen.org/publication/PubMed/23155027" } ] }, { "title": "DNA methylation analysis of the gene CDKN2B in Gallus gallus (chicken).", "journal": "Folia biologica", "date": "2013", "authors": "Gryzi\u0144ska Magdalena, Andraszek Katarzyna, Jocek Grzegorz", "evidence": [ { "database": "RefSeq", "id": "NP_989764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989764" } ], "reference": [ { "type": "PubMed", "id": "24279164", "url": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q7ZZZ5-1", "uniprot_ac": "Q7ZZZ5", "uniprot_id": "Q7ZZZ5_CHICK", "mass": { "chemical_mass": 15089.0, "monoisotopic_mass": 15089.0 }, "refseq": { "ac": "NP_001007924", "name": "fatty acid-binding protein, intestinal", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007924" }, "gene_names": [ { "name": "FABP2", "type": "recommended", "evidence": [ { "id": "Q7ZZZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ] }, { "name": "FABP2", "type": "synonym", "evidence": [ { "id": "NP_001007924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007924" } ] }, { "name": "FABP", "type": "synonym", "evidence": [ { "id": "NP_001007924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007924" } ] } ], "protein_names": [ { "name": 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The reference sequence was derived from JAENSK010000074.1. 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"FABP2", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5", "locus": { "chromosome": "4", "start_pos": 54236037, "end_pos": 54233074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005505", "url": "https://www.ensembl.org/id/ENSGALG00010005505" } ] } } ], "crossref": [ { "id": "ENSGALG00000011986", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19445", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19445", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422678", "url": "https://www.ncbi.nlm.nih.gov/gene/422678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422678", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMEAMGV", "url": "https://omabrowser.org/oma/group/FMEAMGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q7ZZZ5", "url": "https://www.orthodb.org/?gene=Q7ZZZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7ZZZ5-1", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFNGTWKIEKNENYEKFMEAMGVNVMKRKLGAHDNLKLTIQQDGNKFLVKESSNFRTIDIEFTLGVSFEYSLADGTELSGSWNLEGNKLVGTFTRKDNGKVLTAYREIVGSELIQTYVYEGVEAKRIFKKE", "length": 132, "header": "tr|Q7ZZZ5-1|Q7ZZZ5_CHICK Isoform 1 of Fatty acid-binding protein, intestinal OS=Gallus gallus OX=9031 GN=FABP2 PE=3 SV=1 CANONICAL=Q7ZZZ5-1" }, "isoforms": [ { "isoform_ac": "Q7ZZZ5-1", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5/entry#Q7ZZZ5-1", "sequence": { "sequence": "MAFNGTWKIEKNENYEKFMEAMGVNVMKRKLGAHDNLKLTIQQDGNKFLVKESSNFRTIDIEFTLGVSFEYSLADGTELSGSWNLEGNKLVGTFTRKDNGKVLTAYREIVGSELIQTYVYEGVEAKRIFKKE", "length": 132, "header": "tr|Q7ZZZ5-1|Q7ZZZ5_CHICK Isoform 1 of Fatty acid-binding protein, intestinal OS=Gallus gallus OX=9031 GN=FABP2 PE=3 SV=1 CANONICAL=Q7ZZZ5-1" }, "locus": { "chromosome": "4", "start_pos": 54235530, "end_pos": 54233091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013164.1", "url": "https://www.ensembl.org/id/ENSGALT00010013164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007726.1", "url": "https://www.ensembl.org/id/ENSGALP00010007726.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Epistatic effect between ACACA and FABP2 gene on abdominal fat traits in broilers.", "journal": "Journal of genetics and genomics = Yi chuan xue bao", "date": "2010-08", "authors": "Hu Guo, Wang Shouzhi, Tian Jianwei, Chu Lili, Li Hui", "evidence": [ { "database": "RefSeq", "id": "NP_001007924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007924" } ], "reference": [ { "type": "PubMed", "id": "20816383", "url": "https://glygen.org/publication/PubMed/20816383" } ] } ], "pathway": [ { "id": "gga:422678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422678", "resource": "KEGG Pathway" }, { "id": "R-GGA-163560", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I8X9-1", "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "Fabp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFDGNWKVDRSDNYDKFMEKMGVNVVKRKLAAHDNLKLTITQDGNKFTVKESSTFRNIDIVFELGVNFTYSLADGTELNGTWSLDGNKLIGQFKRVDNGKELIAIREISGGELIQTYKYEGVEAKRIFKKE", "length": 132 }, "evidence": [ { "id": "Q7ZZZ5", "url": "https://omabrowser.org/oma/group/Q7ZZZ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P02693-1", "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "Fabp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFDGTWKVDRNENYEKFMEKMGINVVKRKLGAHDNLKLTITQEGNKFTVKESSNFRNIDVVFELGVDFAYSLADGTELTGTWTMEGNKLVGKFKRVDNGKELIAVREISGNELIQTYTYEGVEAKRIFKKE", "length": 132 }, "evidence": [ { "id": "Q7ZZZ5", "url": "https://omabrowser.org/oma/group/Q7ZZZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12104-1", "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "FABP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSTFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD", "length": 132 }, "evidence": [ { "id": "Q7ZZZ5", "url": "https://omabrowser.org/oma/group/Q7ZZZ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "long-chain fatty acid binding", "id": "GO:0036041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036041", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ], "pmid": "" }, { "name": "intestinal lipid absorption", "id": "GO:0098856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098856", "evidence": [ { "database": "UniProtKB", "id": "Q7ZZZ5", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q7ZZZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZZZ5" }, { "id": "PS00214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytosolic fatty-acid binding proteins", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 22, "start_aa": "Gly", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q800L1-1", "uniprot_ac": "Q800L1", "uniprot_id": "SURF1_CHICK", "mass": { "chemical_mass": 35210.0, "monoisotopic_mass": 35210.0 }, "refseq": { "ac": "NP_001012671", "name": "surfeit locus protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" }, "gene_names": [ { "name": "SURF1", "type": "recommended", "evidence": [ { "id": "Q800L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ] }, { "name": "SURF-1", "type": "synonym", "evidence": [ { "id": "NP_001012671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" }, { "id": "Q800L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ] }, { "name": "SURF1", "type": "synonym", "evidence": [ { "id": "NP_001012671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" } ] } ], "protein_names": [ { "name": "Surfeit locus protein 1", "type": "recommended", "evidence": [ { "id": "Q800L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q800L1/entry#names_and_taxonomy" } ] }, { "name": "surfeit 1", "type": "synonym", "evidence": [ { "id": "NP_001012671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" } ] }, { "name": "surfeit locus protein 1", "type": "synonym", "evidence": [ { "id": "NP_001012671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01067529.1, HAEK01139532.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On or before Jul 23, 2005 this sequence version replaced XP_415440.1, XP_428626.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671" } ] }, { "annotation": "May play a role in mitochondrial respiratory chain complex IV assembly. Probably involved in the biogenesis of the COX complex.", "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1#function" }, { "database": "UniProtKB", "id": "Q15526", "url": "https://www.uniprot.org/uniprotkb/Q15526#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SURF1", "url": "https://www.uniprot.org/uniprotkb/Q800L1", "locus": { "chromosome": "17", "start_pos": 7475221, "end_pos": 7479797, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028859", "url": "https://www.ensembl.org/id/ENSGALG00010028859" } ] } } ], "crossref": [ { "id": "Q800L1", "url": "https://alphafold.ebi.ac.uk/entry/Q800L1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033754", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033754", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417157", "url": "https://www.ncbi.nlm.nih.gov/gene/417157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417157", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYSRDVA", "url": "https://omabrowser.org/oma/group/WYSRDVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q800L1", "url": "https://www.orthodb.org/?gene=Q800L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q800L1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q800L1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001012671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q800L1-1", "url": "https://www.uniprot.org/uniprotkb/Q800L1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATWGLLLRAGPRLLRERRARISHCLLRRTFFGFPRTKAGSAVTQQGDVCLRLCSPRSSTTATSAAGEDAWLKWGLLLVPLTAFCLGTWQIQRRKWKLDLIAQLASRLSSEPIPLTLDPMELKELEYRPVKVRGHFDHSKELYILPRSLVDPEREAREAGKLTSHAENGANVITPFYCTELGVTILVNRGFVPKKKLKPETRLKGQIEEEIDLTGVVRLSEKRKPFVPENNIEKNRWHYRDLEAMAKVTGAEPIFIDADFRSTVPGGPIGGQTRVSLRNEHMQYIVTWYGLCAATSFLWYRKFIQKIPL", "length": 309, "header": "sp|Q800L1-1|SURF1_CHICK Isoform 1 of Surfeit locus protein 1 OS=Gallus gallus OX=9031 GN=SURF1 PE=3 SV=1 CANONICAL=Q800L1-1" }, "isoforms": [ { "isoform_ac": "Q800L1-1", "url": "https://www.uniprot.org/uniprotkb/Q800L1/entry#Q800L1-1", "sequence": { "sequence": "MATWGLLLRAGPRLLRERRARISHCLLRRTFFGFPRTKAGSAVTQQGDVCLRLCSPRSSTTATSAAGEDAWLKWGLLLVPLTAFCLGTWQIQRRKWKLDLIAQLASRLSSEPIPLTLDPMELKELEYRPVKVRGHFDHSKELYILPRSLVDPEREAREAGKLTSHAENGANVITPFYCTELGVTILVNRGFVPKKKLKPETRLKGQIEEEIDLTGVVRLSEKRKPFVPENNIEKNRWHYRDLEAMAKVTGAEPIFIDADFRSTVPGGPIGGQTRVSLRNEHMQYIVTWYGLCAATSFLWYRKFIQKIPL", "length": 309, "header": "sp|Q800L1-1|SURF1_CHICK Isoform 1 of Surfeit locus protein 1 OS=Gallus gallus OX=9031 GN=SURF1 PE=3 SV=1 CANONICAL=Q800L1-1" }, "locus": { "chromosome": "17", "start_pos": 7479754, "end_pos": 7476600, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069805.1", "url": "https://www.ensembl.org/id/ENSGALT00010069805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042931.1", "url": "https://www.ensembl.org/id/ENSGALP00010042931.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417157", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4H7-1", "protein_name": "SURF1-like protein", "gene_name": "SURF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGQPKAETVRDPEEKHNQSRRFARCLPGLAWRPSRSGSSSAEATAAKAHDDAFLQWFLLLIPGTAFGLGTWQVQRRKWKLKLIAELESRIMAEPIPLPADPLELRNLEYRPVKVRGHFDHSKELYLMPRTMVDPAREARDAGRLSSTAESGAHVVTPFHCTDLGITILVNRGFVPRKKVNPETRLKGQIEGEVDLVGMVRLTETRKPFVPENNPERNHWHYRDLEAMARLTGAEPIFIDADFKSTVPGGPVGGQTRVTLRNEHLQYIITWYGLCAATSYLWCKKFLRRPPAV", "length": 293 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HDJ2-1", "protein_name": "SURF1-like protein", "gene_name": "LOC100770865", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVMAFAVLRQRMMRWPQSSYAGLAPLRVARGSVLGFSFRSGMVWRPSSSTAEAAATKAEDSSFLQWFLLLIPATAFGLGTWQVQRRKWKLKLIAELESRVMAEPIPLPADLMELKSMEYRPVKVRGHFDHSKELYIMPRTMVDPAREAQDAGRISSSMESGAYVVTPFHCSDLGITILVNRGFVPKKKVNPETRQKGQVLGEVDLVGIVRLTETRKPFVPENSPQQNHWHYRDLEAMAKITGADPIFIDADFQSTIPGGPIGGQTRVTLRNEHMQYIITWYGLCAATSYLWFQKFVRRTPGL", "length": 304 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P09925-1", "protein_name": "Surfeit locus protein 1", "gene_name": "Surf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVMALAVLPRRMTRWSQWAYAGRAQFCAVRRSVFGFSVRSGMVCRPRRCCSSTAETAAAKAEDDSFLQWFLLLIPATAFGLGTWQVQRRKWKLKLIAELESRVMAEPIPLPADPMELKNLEYRPVKVRGHFDHSKELYIMPRTMVDPVREARDAGRLSSTESGAHVVTPFHCSDLGVTILVNRGFVPRKKVNPETRQKGQVLGEVDLVGIVRLTENRKPFVPENSPERNHWYYRDLEAMAKITGADPIFIDADFHSTAPGGPIGGQTRVTLRNEHMQYILTWYGLCAATSYLWFQKFVRRTPIM", "length": 306 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15526-1", "protein_name": "Surfeit locus protein 1", "gene_name": "SURF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAALQLGLRAAGLGRAPASAAWRSVLRVSPRPGVAWRPSRCGSSAAEASATKAEDDSFLQWVLLLIPVTAFGLGTWQVQRRKWKLNLIAELESRVLAEPVPLPADPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQIEGEVDLIGMVRLTETRQPFVPENNPERNHWHYRDLEAMARITGAEPIFIDANFQSTVPGGPIGGQTRVTLRNEHLQYIVTWYGLSAATSYLWFKKFLRGTPGV", "length": 300 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q556J9-1", "protein_name": "SURF1-like protein", "gene_name": "surf1-1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKNKKGFKLFFIFPVIAFGLGTWQVYRYDWKKRLIQRAKDRMEEDPIELSNSFIKNFKGSSFGDLNKYEFRRVYLNGKVIDNQYVLLGPRSIDGTLGYYVISPLQLSDGTRILLNRGWSASTPKSNYKIPYAIEELKLIHQKEKEQGQQQGNQESILYRYFNILGVISKTKERGSAFTPTNQPEKGQWYSLDVDAMADQLNTEPLMINTMDETEINSKPSSLPNPQFKRFDNDVESSFHNKHMSYIGTWYTLSASLFFIYFRYMRKLPK", "length": 270 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SE51-1", "protein_name": "Surfeit locus protein 1", "gene_name": "SURF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSLSKILTRSNTKRYWCSTTTSISASPSLPKQFWSRHFSAVADSSSSSSAALGSQSSSSAPPQENKRGSKWSQLLLFLPGAITFGLGSWQIVRREEKFKTLEYQQQRLNMEPIKLNIDHPLDKNLNALEFRRVSCKGVFDEQRSIYLGPRSRSISGITENGFFVITPLMPIPGDLDSMQSPILVNRGWVPRSWREKSQESAEAEFIANQSTKAKSPSNEPKSWWKFWSKTPVITKEHISAVKPVEVVGVIRGGENPSIFVPSNDPSTGQWFYVDVPAMARAVGLPENTIYVEDVHEHVDRSRPYPVPKDINTLIRSKVMPQDHLNYSITWYSLSAAVTFMAYKRLKAKPVRR", "length": 354 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9U4F3-1", "protein_name": "SURF1-like protein", "gene_name": "Surf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRLGNQMCRQVAFNIQTVFRNPGTANNPRLITRKMTQQRPPVNWTTSIPNQAAKDKEKIAPLGWFLLLIPATTFGLGCWQVKRKIWKEQLIKDLNKQLSTAPVALPDDLTDLAQMEYRLVKIRGRFLHDKEMRLGPRSLIRPDGVETQGGLFSQRDSGNGYLIVTPFQLADRDDIVLVNRGWVSRKQVEPETRPLGQQQAEVELTAVVRKGEARPQFTPDHKGNVYLYRDLARMCAATGAAPVFLDAVYDPQTAAHAPIGGQTRVTLRNDHLSYLVTWFSLSAATSFLWYRQIVKRIPF", "length": 300 }, "evidence": [ { "id": "Q800L1", "url": "https://omabrowser.org/oma/group/Q800L1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytochrome-c oxidase activity", "id": "GO:0004129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004129", "evidence": [ { "database": "UniProtKB", "id": "Q800L1", "url": "https://www.uniprot.org/uniprotkb/Q800L1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q800L1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q800L1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q800L1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q85A52-1", "uniprot_ac": "Q85A52", "uniprot_id": "Q85A52_CHICK", "mass": { "chemical_mass": 66321.0, "monoisotopic_mass": 66321.0 }, "refseq": { "ac": "YP_010037850", "name": "NADH dehydrogenase subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037850" }, "gene_names": [ { "name": "ND5", "type": "recommended", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ] }, { "name": "ND5", "type": "synonym", "evidence": [ { "id": "YP_010037850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037850" } ] } ], "protein_names": [ { "name": "NADH-ubiquinone oxidoreductase chain 5", "type": "recommended", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85A52/entry#names_and_taxonomy" } ] }, { "name": "7.1.1.2", "type": "synonym", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85A52/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase subunit 5", "type": "synonym", "evidence": [ { "id": "YP_010037850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037850" } ] } ], "function": [ { "annotation": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52#function" }, { "database": "UniProtKB", "id": "RU003404", "url": "https://www.uniprot.org/uniprotkb/RU003404#function" } ] }, { "annotation": "PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to NC_053523:11849-13666. Method: conceptual translation.", "evidence": [ { "database": "RefSeq", "id": "YP_010037850", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037850" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ND5", "url": "https://www.uniprot.org/uniprotkb/Q85A52", "locus": { "chromosome": "MT", "start_pos": 13666, "end_pos": 11849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000033", "url": "https://www.ensembl.org/id/ENSGALG00010000033" } ] } } ], "crossref": [ { "id": "63549495", "url": "https://www.ncbi.nlm.nih.gov/gene/63549495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GVGIMSF", "url": "https://omabrowser.org/oma/group/GVGIMSF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q85A52", "url": "https://www.orthodb.org/?gene=Q85A52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42829:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42829:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00361", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00361", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "YP_010037850", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29091", "url": "https://www.rhea-db.org/rhea/29091", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q85A52-1", "url": "https://www.uniprot.org/uniprotkb/Q85A52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METPLLLNTLTTLTLLTLLTPIILPPLLNLKNSPMSITKTIKTAFLISLIPTTIFIHSGAESIATHWEWQFIPNFKIPISLKMDMYSMMFFPIALFVTWSILEFATWYMASEPFITKFFTYLLTFLIAMLTLTIANNMFLLFVGWEGVGIMSFLLIGWWQGRAEANTAALQAMIYNRIGDIGLILSMAWLASSLNTWEIQQITHPNQTPTLPLLGLILAATGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRTHPFLSSNKTALTTCLCLGALSTLFAATCALTQNDIKKIIAFSTSSQLGLMMVTIGLDLPQLAFLHISTHAFFKAMLFLCSGLIIHSLNGEQDIRKMGCLQKTLPMTTSCLTIGNLALMGTPFLAGFYSKDLIIENLNTSYINTWALSLTLLATSFTATYSLRMTLLVQTGHTRTPAITPINENTPPAILPIMRLALGSIMAGLLISSLILPPKTPPMTMPTITKTAAIIVTTLGIILALELSSLSYSLTPPKHNPLMNFSSSLGYFNPLTHRISPSILLHTGQKIASHLIDMAWYKKMGPEGLANLHLTMTKISTTLHTGLIKSYLGSFALTILTTILLIQK", "length": 605, "header": "tr|Q85A52-1|Q85A52_CHICK Isoform 1 of NADH-ubiquinone oxidoreductase chain 5 OS=Gallus gallus OX=9031 GN=ND5 PE=3 SV=1 CANONICAL=Q85A52-1" }, "isoforms": [ { "isoform_ac": "Q85A52-1", "url": "https://www.uniprot.org/uniprotkb/Q85A52/entry#Q85A52-1", "sequence": { "sequence": "METPLLLNTLTTLTLLTLLTPIILPPLLNLKNSPMSITKTIKTAFLISLIPTTIFIHSGAESIATHWEWQFIPNFKIPISLKMDMYSMMFFPIALFVTWSILEFATWYMASEPFITKFFTYLLTFLIAMLTLTIANNMFLLFVGWEGVGIMSFLLIGWWQGRAEANTAALQAMIYNRIGDIGLILSMAWLASSLNTWEIQQITHPNQTPTLPLLGLILAATGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRTHPFLSSNKTALTTCLCLGALSTLFAATCALTQNDIKKIIAFSTSSQLGLMMVTIGLDLPQLAFLHISTHAFFKAMLFLCSGLIIHSLNGEQDIRKMGCLQKTLPMTTSCLTIGNLALMGTPFLAGFYSKDLIIENLNTSYINTWALSLTLLATSFTATYSLRMTLLVQTGHTRTPAITPINENTPPAILPIMRLALGSIMAGLLISSLILPPKTPPMTMPTITKTAAIIVTTLGIILALELSSLSYSLTPPKHNPLMNFSSSLGYFNPLTHRISPSILLHTGQKIASHLIDMAWYKKMGPEGLANLHLTMTKISTTLHTGLIKSYLGSFALTILTTILLIQK", "length": 605, "header": "tr|Q85A52-1|Q85A52_CHICK Isoform 1 of NADH-ubiquinone oxidoreductase chain 5 OS=Gallus gallus OX=9031 GN=ND5 PE=3 SV=1 CANONICAL=Q85A52-1" }, "locus": { "chromosome": "Mitochondrion", "start_pos": 13663, "end_pos": 11849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000033.1", "url": "https://www.ensembl.org/id/ENSGALT00010000033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000012.1", "url": "https://www.ensembl.org/id/ENSGALP00010000012.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "P03915-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "MT-ND5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMHTTMTTLTLTSLIPPILTTLVNPNKKNSYPHYVKSIVASTFIISLFPTTMFMCLDQEVIISNWHWATTQTTQLSLSFKLDYFSMMFIPVALFVTWSIMEFSLWYMNSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYARADANTAAIQAILYNRIGDIGFILALAWFILHSNSWDPQQMALLNANPSLTPLLGLLLAAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPLAENSPLIQTLTLCLGAITTLFAAVCALTQNDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTIGSLALAGMPFLTGFYSKDHIIETANMSYTNAWALSITLIATSLTSAYSTRMILLTLTGQPRFPTLTNINENNPTLLNPIKRLAAGSLFAGFLITNNISPASPFQTTIPLYLKLTALAVTFLGLLTALDLNYLTNKLKMKSPLCTFYFSNMLGFYPSITHRTIPYLGLLTSQNLPLLLLDLTWLEKLLPKTISQHQISTSIITSTQKGMIKLYFLSFFFPLILTLLLIT", "length": 603 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P03921-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "Mtnd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIFTTSILLIFILLLSPILISMSNLIKHINFPLYTTTSIKFSFIISLLPLLMFFHNNMEYMITTWHWVTMNSMELKMSFKTDFFSILFTSVALFVTWSIMQFSSWYMHSDPNINRFIKYLTLFLITMLILTSANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMVWFSLNMNSWELQQIMFSNNNDNLIPLMGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFHPLTTNNNFILTTMLCLGALTTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTLGMNQPHLAFLHICTHAFFKAMLFMCSGSIIHSLADEQDIRKMGNITKIMPFTSSCLVIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALLITLIATSMTAMYSMRIIYFVTMTKPRFPPLISINENDPDLMNPIKRLAFGSIFAGFVISYNIPPTSIPVLTMPWFLKTTALIISVLGFLIALELNNLTMKLSMNKANPYSSFSTLLGFFPSIIHRITPMKSLNLSLKTSLTLLDLIWLEKTIPKSTSTLHTNMTTLTTNQKGLIKLYFMSFLINIILIIILYSINLE", "length": 607 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11661-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "Mt-nd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNMMTSSILMILILLTTPIIISMTNLPKLIDFPSYATSSIKFSFLLSLLPLLLFFHHNTEYMITNWHWLTINSIKLTMSFKIDYFSILFLSVALFVTWSIMQFSSWYMHSDPHINRFIKYLMMFLITMLILTSANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRVGDIGFILAMTWFCLNMNSWELQQIFLTNTNNLVPLTGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLMIRFHPLTSNNSTIMTAMLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTLGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGNMMKAMPFTSSCLIIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALMITLIATSMTAVYSMRIIYFVTMTKPRYSPLITINENNPNLINPIKRLALGSILAGFLISLNIPPTNIQILTMPWHLKMTALLITILGFAIALELNNLTLNLSMSKPTKLSSFSTSLGYYPPIMHRIIPQKTLNSSYKLSLNLLDLIWLEKTIPKSTSITQTQLSKMMSNQKGLIKLYFLSFLITISLIFILHTLNPEWFQ", "length": 609 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q85BD6-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "ND5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMFSSLSLVTLLLLTTPIMMMSFNTYKPSNYPLYVKTAISYAFITSMIPTMMFIHSGQELIISNWHWLTIQTLKLSLSFKMDYFSMMFIPVALFVTWSIMEFSMWYMYSDPNINKFFKYLLLFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRIGDIGFILAMAWFLTNLNTWDLQQIFMLNPSDSNMPLIGLALAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLTENNKYIQSITLCLGAITTLFTAMCALTQNDIKKIIAFSTSSQLGLMMVTIGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLFKAMPFTTTALIVGSLALTGMPFLTGFYSKDLIIEAANTSYTNAWALLMTLIATSFTAIYSTRIIFFALLGQPRFPTLVNINENNPLLINSIKRLLIGSLFAGYIISNNIPPTTIPQMTMPYYLKTTALIVTILGFILALEISNMTKNLKYHYPSNAFKFSTLLGYFPTIMHRLAPYMNLSMSQKSASSLLDLIWLEAILPKTISLAQMKASTLVTNQKGLIKLYFLSFLITILISMILFNFHE", "length": 606 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9MIY0-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "mt-nd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDMIMPLTLILIFAVLSYPLLKPKSYSKSNNSFQAWNAVHVSFLISLIPLTMMLYKESDHVVMCWSWMNTQAFNVDLSFKFDYYSVTFTSIALFITWSILEFASWYMASYPQKELFYKYLLLFLMSMIILVTANNLFQLFIGWEGVGIMSFLLIGWWFGRTEANTASLQAVIYNRMGDIGFILTLAWMAMYLNSWDIQQIFILSKDFDMTIPQIGLIIAATGKSAQFTLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPIMETNKLAPTICLCLGALTTLFAATCALTQNDIKKIVAFSTSSQLGLMMVAIGLNQPHLAFFHICTHAFFKAMLFLCSGAIIHSLNNEQDIRKMGGTYHTLPMTTNYLTIGKMALMGTPFLAGFFSKDAILEAMTTSHLNAWALTLTLIATSFTAVYSFRMIYLVCLGSPRHKTYETIDENHIPTNTIQRLAWGSIIAGLIISYTMIPLKTPILTMPIYLKLAAILVTLLGIILGLEISTLANKINKNTTPGIPFHFSISLIFFPILHRLIPMRKLFMGESAATKIEKSWSELFGPCGIAFTLMTVATFVKDHRMASIKSYLAVFLTSIILKMMMLKLYT", "length": 606 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9TDR1-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "MT-ND5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPFASLTLTTLIILTIPIMMSNSNIYKTNLYPNYVKTTVSYAFTLSLVPLLMFMHTGQEMIISNWHWMTLQTVELSLSFKMDYFSVMFIPVALFVTWSIMEFSMWYMHSDPFINRFFKYLVLFLITMMILVTANNLFQLFIGWEGVGIMSFLLIGWWHGRTDANTAALQAILYNRIGDIGFVLSMAWFLTHSNAWDLQQIFMLNNECPNMPLIGLLLAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRFYPLMETNKLVQTMTLCLGAITTLFTALCAITQNDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICMHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLYKAMPFTTTALIIGSLALTGMPYLTGFYSKDLIIEAVNMSYTNAWALLMTLIATSLTAAYSTRIIFFAFLGKPRFPPLVLINENNPLLINSIKRLLIGSIFAGFIISNNIPPMTVPNTTMPLYMKMTALIVTIMGFMLALELNNTTYYLKFKYPSQTYKFSNMLGYYPSIMHRLPTYHNLSMSQKSASSLLDLIWLETILPKTTSFIQMKMSIMVSNQKGLIKLYFLSFLITIMISMTLFNYHE", "length": 606 }, "evidence": [ { "id": "Q85A52", "url": "https://omabrowser.org/oma/group/Q85A52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" }, { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" }, { "name": "electron transport coupled proton transport", "id": "GO:0015990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015990", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "Q85A52", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29091", "name": "", "equation": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P18936-1", "P18938-1", "P18940-1", "P18937-1", "P18939-1", "P18941-1", "P18942-1", "A0A1D5PI06-1", "Q85A52-1", "Q85BF7-1", "A0A8V0ZIP4-1" ], "evidence": [ { "id": "29091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29091" } ] }, { "id": "R-GGA-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI06-1", "A0A8V0ZIP4-1", "P18936-1", "P18938-1", "P18939-1", "P18941-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-163217", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163217" } ] }, { "id": "R-GGA-5419271", "name": "55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ALN3-1", "P18944-1", "P18936-1", "P18938-1", "P18939-1", "P18942-1", "P18945-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-5419271", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419271" } ] }, { "id": "R-GGA-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XS06-1", "A0A1D5PI06-1", "A0A8V0ZIP4-1", "F1NEF6-1", "P18936-1", "P18938-1", "P18939-1", "P18941-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-6799179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799179" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PI06", "gene_name": "NDUFV2", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "A0A1D5PI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI06" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "A0A1D5PI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI06" } ] } ] }, { "uniprot_ac": "A0A8V0XS06", "gene_name": "NDUFAF7", "activity": [ { "ec_number": "2.1.1.320", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A8V0XS06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS06" } ] }, { "ec_number": "2.1.1.320", "activity": "", "evidence": [ { "id": "A0A8V0XS06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS06" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP4", "gene_name": "NDUFS8", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "A0A8V0ZIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP4" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "A0A8V0ZIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP4" } ] } ] }, { "uniprot_ac": "A0A8V1ALN3", "gene_name": "MRPL58", "activity": [ { "ec_number": "3.1.1.29", "activity": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "A0A8V1ALN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN3" } ] }, { "ec_number": "3.1.1.29", "activity": "", "evidence": [ { "id": "A0A8V1ALN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN3" } ] } ] }, { "uniprot_ac": "F1NEF6", "gene_name": "ACAD9", "activity": [ { "ec_number": "1.3.8.7", "activity": "a medium-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.8", "activity": "a long-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.7", "activity": "", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.8", "activity": "", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] } ] }, { "uniprot_ac": "P18936", "gene_name": "MT-ND1", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18936" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18936" } ] } ] }, { "uniprot_ac": "P18937", "gene_name": "MT-ND2", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18937" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18937" } ] } ] }, { "uniprot_ac": "P18938", "gene_name": "MT-ND3", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18938" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18938" } ] } ] }, { "uniprot_ac": "P18939", "gene_name": "MT-ND4", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18939" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18939" } ] } ] }, { "uniprot_ac": "P18940", "gene_name": "MT-ND5", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18940" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18940" } ] } ] }, { "uniprot_ac": "P18941", "gene_name": "MT-ND6", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18941", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "P18944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18944" } ] } ] }, { "uniprot_ac": "P18945", "gene_name": "MT-CO3", "activity": [ { "ec_number": "7.1.1.9", "activity": "4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out).", "evidence": [ { "id": "P18945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18945" } ] }, { "ec_number": "7.1.1.9", "activity": "", "evidence": [ { "id": "P18945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18945" } ] } ] }, { "uniprot_ac": "Q85A52", "gene_name": "ND5", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": 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Method: conceptual translation.", "evidence": [ { "database": "RefSeq", "id": "YP_010037841", "url": "https://www.ncbi.nlm.nih.gov/protein/YP_010037841" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ND2", "url": "https://www.uniprot.org/uniprotkb/Q85BF7", "locus": { "chromosome": "MT", "start_pos": 5053, "end_pos": 4015, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000011", "url": "https://www.ensembl.org/id/ENSGALG00010000011" } ] } } ], "crossref": [ { "id": "63549482", "url": "https://www.ncbi.nlm.nih.gov/gene/63549482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HFWVPEV", "url": "https://omabrowser.org/oma/group/HFWVPEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q85BF7", "url": "https://www.orthodb.org/?gene=Q85BF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46552", "database": "PANTHER", "categories": [ "Protein 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PE=3 SV=1 CANONICAL=Q85BF7-1" }, "isoforms": [ { "isoform_ac": "Q85BF7-1", "url": "https://www.uniprot.org/uniprotkb/Q85BF7/entry#Q85BF7-1", "sequence": { "sequence": "MNPHAKLICTVSLIMGTSITISSNHWILAWTGLEINTLAIIPLISKSHHPRAIEATIKYFLTQSTASALILFSSMTNAWSTGQWDITQLNHPTSCLMLTMAIAIKLGLVPFHFWFPEVLQGSSLITALLLSTLMKLPPITLLLLTSQSLNTTLLTLLAISSTLIGGWMGLNQTQTRKILAFSSISHLGWMIMIISYNPQLTILTFILYTIMTSTVFLSLAQIKVLKLSTMLISWTKTPMLNATVMLTLLSLAGLPPLTGFMPKWLIIQELTKQEMTPMATIITMLSLLSLFFYLRLAYHSTITLPPNSSNHMKLWRTNKTLNTPTAILTALSTTLLPLSPLIITML", "length": 346, "header": "tr|Q85BF7-1|Q85BF7_CHICK Isoform 1 of NADH-ubiquinone oxidoreductase chain 2 OS=Gallus gallus OX=9031 GN=ND2 PE=3 SV=1 CANONICAL=Q85BF7-1" }, "locus": { "chromosome": "Mitochondrion", "start_pos": 5052, "end_pos": 4015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000011.1", "url": "https://www.ensembl.org/id/ENSGALT00010000011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000003.1", "url": "https://www.ensembl.org/id/ENSGALP00010000003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "O79875-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "MT-ND2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPIIYTTLIMTVMSGTMLVMISSHWLLIWIGFEMNLLAMIPVLMKNFNPRATEAATKYFLTQATASMMLMMAIIINLLYSGQWTITKMFNPVAMTMMTMALAMKLGLSPFHFWVPEVTQGISLQAGLLLLTWQKLAPLSVLCQISQSINPNLMLTMAMLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNTTMTILNLLIYITMTLAMFMLLIHSSATTTLSLSHTWNKMPVITSLMMVTLLSMGGLPPLSGFMPKWMIIQEMTKNESIIMPTLMAMTALLNLYFYMRLAYSSSLTMFPSTNNMKMKWQFEHTKQMKLLPTMIVLSTLVLPMTPALSSLN", "length": 347 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P03891-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "MT-ND2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPLAQPVIYSTIFAGTLITALSSHWFFTWVGLEMNMLAFIPVLTKKMNPRSTEAAIKYFLTQATASMILLMAILFNNMLSGQWTMTNTTNQYSSLMIMMAMAMKLGMAPFHFWVPEVTQGTPLTSGLLLLTWQKLAPISIMYQISPSLNVSLLLTLSILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWAIIEEFTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFLPTLIALTTLLLPISPFMLMIL", "length": 347 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P03893-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "mt-Nd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPITLAIIYFTIFLGPVITMSSTNLMLMWVGLEFSLLAIIPMLINKKNPRSTEAATKYFVTQATASMIILLAIVLNYKQLGTWMFQQQTNGLILNMTLMALSMKLGLAPFHFWLPEVTQGIPLHMGLILLTWQKIAPLSILIQIYPLLNSTIILMLAITSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPSLTLLNLMIYIILTAPMFMALMLNNSMTINSISLLWNKTPAMLTMISLMLLSLGGLPPLTGFLPKWIIITELMKNNCLIMATLMAMMALLNLFFYTRLIYSTSLTMFPTNNNSKMMTHQTKTKPNLMFSTLAIMSTMTLPLAPQLIT", "length": 345 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P03896-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "mt:ND2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFNNSSKILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQVLASTVLLFSSILLMLKNNMNNEINESFTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLMTWQKIAPLMLISYLNIKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTLCNQYFMLTLMMMSTLITLFFYLRICYSAFMMNYFENNWIMKMNMNSINYNMYMIMTFFSIFGLFLISLFYFMF", "length": 341 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P11662-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "Mt-nd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPITLIIIYFTILMGPVITMSSSNLLLMWVGLEMSLLAIIPLLANKKSPRSTEAATKYFLTQATASMIILLVIILNYKQSGMWTLQQQTNNMLLNMMLISLAMKLGLAPFHYWLPEVTQGIPLHIGLILLTWQKIAPLSILYQFYQLLNPTITTILAISSVFVGAWGGLNQTQTRKIMAYSSIAHMGWMTAILPYNPNLTLLNLTIYILLTVPMFITLMTNSATTINTLSLAWNKTPMILTMTSIILLSLGGLPPLTGFLPKWAIISELLKNNCSTLSTLMAIMALLSLFFYTRLIYSMSLTMFPTNNNSKMISHHHQNPKHNFILPTLTVLSTLTLPLSSQLIT", "length": 346 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6QTH0-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "ND2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINVMFSGQWTVMKLFSPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLMKKMTFLPTMVVLSTMMLPLTPMLSVLE", "length": 347 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9MIY9-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 2", "gene_name": "mt-nd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPYVLMILMSSLGLGTTLTFSSSHWILAWMGLEINTLAIVPLMAQQHHPRAVEATTKYFLIQAAAAAMILFTSTTNAWISGQWDVTGMPGPATSTAMMFALALKIGLAPMHFWLPEVLQGLDLLTGLILSTWQKLAPMALIIQTTQTTDPLILTSLGIASSLIGGWSGLNQTQLRKILAYSSIAHMGWMIIVIQYAPQLTLIALGTYIFMTSAAFLTLKVLSATKINTLTTTWPKSPILAAIATLVMLSLGGLPPLTGFMPKWLILQELTKQDLPATATIMALTALLSLFFYLRLCHAMTLTTSPNTINSAPHWRVQTTQNSLPLTISVTVTMGLLPLTPAILMLTT", "length": 348 }, "evidence": [ { "id": "Q85BF7", "url": "https://omabrowser.org/oma/group/Q85BF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "pmid": "" }, { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "Q85BF7", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29091", "name": "", "equation": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P18936-1", "P18938-1", "P18940-1", "P18937-1", "P18939-1", "P18941-1", "P18942-1", "A0A1D5PI06-1", "Q85A52-1", "Q85BF7-1", "A0A8V0ZIP4-1" ], "evidence": [ { "id": "29091", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29091" } ] }, { "id": "R-GGA-163217", "name": "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI06-1", "A0A8V0ZIP4-1", "P18936-1", "P18938-1", "P18939-1", "P18941-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-163217", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163217" } ] }, { "id": "R-GGA-5419271", "name": "55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ALN3-1", "P18944-1", "P18936-1", "P18938-1", "P18939-1", "P18942-1", "P18945-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-5419271", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419271" } ] }, { "id": "R-GGA-6799179", "name": "Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XS06-1", "A0A1D5PI06-1", "A0A8V0ZIP4-1", "F1NEF6-1", "P18936-1", "P18938-1", "P18939-1", "P18941-1", "Q85A52-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-6799179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799179" } ] }, { "id": "R-GGA-6799202", "name": "The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XS06-1", "A0A8V0ZIP4-1", "F1NEF6-1", "P18936-1", "P18938-1", "P18941-1", "Q85BF7-1" ], "evidence": [ { "id": "R-GGA-6799202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799202" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PI06", "gene_name": "NDUFV2", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "A0A1D5PI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI06" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "A0A1D5PI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI06" } ] } ] }, { "uniprot_ac": "A0A8V0XS06", "gene_name": "NDUFAF7", "activity": [ { "ec_number": "2.1.1.320", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A8V0XS06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS06" } ] }, { "ec_number": "2.1.1.320", "activity": "", "evidence": [ { "id": "A0A8V0XS06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS06" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP4", "gene_name": "NDUFS8", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "A0A8V0ZIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP4" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "A0A8V0ZIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP4" } ] } ] }, { "uniprot_ac": "A0A8V1ALN3", "gene_name": "MRPL58", "activity": [ { "ec_number": "3.1.1.29", "activity": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "A0A8V1ALN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN3" } ] }, { "ec_number": "3.1.1.29", "activity": "", "evidence": [ { "id": "A0A8V1ALN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN3" } ] } ] }, { "uniprot_ac": "F1NEF6", "gene_name": "ACAD9", "activity": [ { "ec_number": "1.3.8.7", "activity": "a medium-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.8", "activity": "a long-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.7", "activity": "", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] }, { "ec_number": "1.3.8.8", "activity": "", "evidence": [ { "id": "F1NEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEF6" } ] } ] }, { "uniprot_ac": "P18936", "gene_name": "MT-ND1", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18936" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18936" } ] } ] }, { "uniprot_ac": "P18937", "gene_name": "MT-ND2", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18937" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18937" } ] } ] }, { "uniprot_ac": "P18938", "gene_name": "MT-ND3", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18938" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18938" } ] } ] }, { "uniprot_ac": "P18939", "gene_name": "MT-ND4", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18939" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18939" } ] } ] }, { "uniprot_ac": "P18940", "gene_name": "MT-ND5", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18940" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18940" } ] } ] }, { "uniprot_ac": "P18941", "gene_name": "MT-ND6", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18941" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18941" } ] } ] }, { "uniprot_ac": "P18942", "gene_name": "MT-ND4L", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P18942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18942" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P18942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18942" } ] } ] }, { "uniprot_ac": "P18944", "gene_name": "MT-CO2", "activity": [ { "ec_number": "7.1.1.9", "activity": "4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out).", "evidence": [ { "id": "P18944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18944" } ] }, { "ec_number": "7.1.1.9", "activity": "", "evidence": [ { "id": "P18944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18944" } ] } ] }, { "uniprot_ac": "P18945", "gene_name": "MT-CO3", "activity": [ { "ec_number": "7.1.1.9", "activity": "4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out).", "evidence": [ { "id": "P18945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18945" } ] }, { "ec_number": "7.1.1.9", "activity": "", "evidence": [ { "id": "P18945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18945" } ] } ] }, { "uniprot_ac": "Q85A52", "gene_name": "ND5", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85A52" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "Q85A52", "database": "UniProtKB", "url": 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"glycosite_overlap": "" }, { "evidence": [ { "id": "Q85BF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q85BF7" }, { "id": "PF00361", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADH:quinone oxidoreductase/Mrp antiporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 288, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "7.1.1.2", "ec_name": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "7.1.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2" }, { "id": "7.1.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=7.1.1.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q8AV16-1", "uniprot_ac": "Q8AV16", "uniprot_id": "Q8AV16_CHICK", "mass": { "chemical_mass": 25968.0, "monoisotopic_mass": 25968.0 }, "refseq": { "ac": "NP_001006328", "name": "B-cell antigen receptor complex-associated protein beta chain precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" }, "gene_names": [ { "name": "CD79B", "type": "recommended", "evidence": [ { "id": "Q8AV16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AV16" } ] }, { "name": "B29", "type": "synonym", "evidence": [ { "id": "NP_001006328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] }, { "name": "CD79B", "type": "synonym", "evidence": [ { "id": "NP_001006328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] } ], "protein_names": [ { "name": "B-cell antigen receptor complex-associated protein beta chain", "type": "recommended", "evidence": [ { "id": "Q8AV16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AV16/entry#names_and_taxonomy" } ] }, { "name": "B-cell antigen receptor complex-associated protein beta chain precursor", "type": "synonym", "evidence": [ { "id": "NP_001006328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] }, { "name": "B-cell antigen receptor complex-associated protein beta chain", "type": "synonym", "evidence": [ { "id": "NP_001006328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] }, { "name": "B-cell-specific glycoprotein B29", "type": "synonym", "evidence": [ { "id": "Q8AV16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AV16/entry#names_and_taxonomy" } ] }, { "name": "CD79b molecule, immunoglobulin-associated beta", "type": "synonym", "evidence": [ { "id": "NP_001006328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] }, { "name": "Ig-beta", "type": "synonym", "evidence": [ { "id": "Q8AV16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AV16/entry#names_and_taxonomy" } ] }, { "name": "Immunoglobulin-associated B29 protein", "type": "synonym", "evidence": [ { "id": "Q8AV16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AV16/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719814.1, AJ395778.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000363.1. On Nov 12, 2021 this sequence version replaced NP_001006328.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ] }, { "annotation": "Data indicate that deletion of mCD8alpha:chIgalpha (immunoglobulin-associated alpha protein)-expressing cells was specific for B cells and required active signaling downstream of the mCD8alpha:chIgalpha receptor.", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" }, { "database": "PubMed", "id": "24516196", "url": "https://glygen.org/publication/PubMed/24516196" } ] }, { "annotation": "Microarray analysis showed CD79B to be among the under-expressed genes in SCA-2 induced bursal cells and this was validated with qRT-PCR.", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" }, { "database": "PubMed", "id": "19945479", "url": "https://glygen.org/publication/PubMed/19945479" } ] }, { "annotation": "Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "Q8AV16", "url": "https://www.uniprot.org/uniprotkb/Q8AV16#function" }, { "database": "UniProtKB", "id": "ARBA00056166", "url": "https://www.uniprot.org/uniprotkb/ARBA00056166#function" } ] }, { "annotation": "These results suggest that CD79B has a cis-acting regulatory element that responds to Marek's disease (MD) and probably cooperates with growth hormone in conferring genetic resistance to MD.", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" }, { "database": "PubMed", "id": "21597060", "url": "https://glygen.org/publication/PubMed/21597060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8AV16", "url": "https://www.uniprot.org/uniprotkb/Q8AV16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD79B", "url": "https://www.uniprot.org/uniprotkb/Q8AV16", "locus": { "chromosome": "27", "start_pos": 1273143, "end_pos": 1278155, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023621", "url": "https://www.ensembl.org/id/ENSGALG00010023621" } ] } } ], "crossref": [ { "id": "ENSGALG00000000251", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419940", "url": "https://www.ncbi.nlm.nih.gov/gene/419940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419940", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVHFICY", "url": "https://omabrowser.org/oma/group/PVHFICY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q8AV16", "url": "https://www.orthodb.org/?gene=Q8AV16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8AV16", "url": "https://www.uniprot.org/uniprotkb/Q8AV16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8AV16-1", "url": "https://www.uniprot.org/uniprotkb/Q8AV16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDFCRRLWVLQVNLWLMAVAAGGIPTDGNSTSNRTGSECVGMWQHPRYIAAKKNTSVHFICYTSQPHAMQWYKALGNGKEFHVLDQSSDRFSINNTNDRISFTISRISYEDNGIYVCDSKNLTEEKRQPNSCGTEIRVMSRSNIQQIQNRNTLKDTIIIIQTILLVIFISVPMLLFLEKGDRKERPEEDHTYEGLEVEQIATYEDITPFRDMKAKWTVGEHPGEE", "length": 226, "header": "tr|Q8AV16-1|Q8AV16_CHICK Isoform 1 of B-cell antigen receptor complex-associated protein beta chain OS=Gallus gallus OX=9031 GN=CD79B PE=4 SV=1 CANONICAL=Q8AV16-1" }, "isoforms": [ { "isoform_ac": "Q8AV16-1", "url": "https://www.uniprot.org/uniprotkb/Q8AV16/entry#Q8AV16-1", "sequence": { "sequence": "MGDFCRRLWVLQVNLWLMAVAAGGIPTDGNSTSNRTGSECVGMWQHPRYIAAKKNTSVHFICYTSQPHAMQWYKALGNGKEFHVLDQSSDRFSINNTNDRISFTISRISYEDNGIYVCDSKNLTEEKRQPNSCGTEIRVMSRSNIQQIQNRNTLKDTIIIIQTILLVIFISVPMLLFLEKGDRKERPEEDHTYEGLEVEQIATYEDITPFRDMKAKWTVGEHPGEE", "length": 226, "header": "tr|Q8AV16-1|Q8AV16_CHICK Isoform 1 of B-cell antigen receptor complex-associated protein beta chain OS=Gallus gallus OX=9031 GN=CD79B PE=4 SV=1 CANONICAL=Q8AV16-1" }, "locus": { "chromosome": "27", "start_pos": 1278069, "end_pos": 1274507, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057510.1", "url": "https://www.ensembl.org/id/ENSGALT00010057510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034943.1", "url": "https://www.ensembl.org/id/ENSGALP00010034943.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cloning and functional characterization of chicken stem cell antigen 2.", "journal": "Developmental and comparative immunology", "date": "2010-03", "authors": "Mao Weifeng, Hunt Henry D, Cheng Hans H", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ], "reference": [ { "type": "PubMed", "id": "19945479", "url": "https://glygen.org/publication/PubMed/19945479" } ] }, { "title": "Allele-specific expression analysis reveals CD79B has a cis-acting regulatory element that responds to Marek's disease virus infection in chickens.", "journal": "Poultry science", "date": "2011-06", "authors": "Meydan H, Yildiz M A, Dodgson J B, Cheng H H", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ], "reference": [ { "type": "PubMed", "id": "21597060", "url": "https://glygen.org/publication/PubMed/21597060" } ] }, { "title": "Negative selection of self-reactive chicken B cells requires B cell receptor signaling and is independent of the bursal microenvironment.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2014-04-01", "authors": "Davani Dariush, Pancer Zeev, Cheroutre Hilde, Ratcliffe Michael J H", "evidence": [ { "database": "RefSeq", "id": "NP_001006328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006328" } ], "reference": [ { "type": "PubMed", "id": "24516196", "url": "https://glygen.org/publication/PubMed/24516196" } ] } ], "pathway": [ { "id": "gga:419940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419940", "resource": "KEGG Pathway" }, { "id": "R-GGA-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ID76-1", "protein_name": "Uncharacterized protein cd79b isoform X1", "gene_name": "cd79b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVLICMFLRSIFTALDLHLLAEAGLCSGELYSFCSLSVTDVYITFRGGFEDFNIMHHFLLGFSVMALIYLSAEGSIIVFQKPRFIGVKTGRTVIIYCVPSNPTRGPARVQWFKNKNYQSSLTNDQRITINDRNNDKNASITLKKVETEDSGTYVCKLNDTFGPGTALQVSRYSEPHAVLMRSRVKDVIIFLQAFLLVLCIVVPLVRLYKLEKKEEAEYEEPEDDHIYEGLEIEQVGGDVYEDISTFAQSSDAAWQVESPCQE", "length": 263 }, "evidence": [ { "id": "Q8AV16", "url": "https://omabrowser.org/oma/group/Q8AV16/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A4X1T0R0-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "CD79B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPALSPGLSNWLVLLLLLLSGETVLEAETKELRDPKGGACSRIWQHPRFVARKRGSMVEIRCYVEDPGIVSWLRKQEADLEPKIFPPEEGRIIQNQTTSEATLIIQGVQFQDNGVYYCKQECSKEPLRTEQGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKPGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 228 }, "evidence": [ { "id": "Q8AV16", "url": "https://omabrowser.org/oma/group/Q8AV16/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8J8XPU7-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "Cd79b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLPSRVPGEMVPPLGLNLHGRKGPNGEEVERRKVAARADTQLHVLPQTLLGLRDRAVTMATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCSKIWQHPRFAAKKRSSMVKFHCHTDYSGVMTWFRQKGNQRPQELFPEDGHISQTRNGSVYTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVKWSVGEHPGQE", "length": 287 }, "evidence": [ { "id": "Q8AV16", "url": "https://omabrowser.org/oma/group/Q8AV16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SAP4-1", "protein_name": "B-cell antigen receptor complex-associated protein beta chain", "gene_name": "CD79B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"Q8AWB6-1", "uniprot_ac": "Q8AWB6", "uniprot_id": "S35B1_CHICK", "mass": { "chemical_mass": 36054.0, "monoisotopic_mass": 36054.0 }, "refseq": {}, "gene_names": [ { "name": "SLC35B1", "type": "recommended", "evidence": [ { "id": "Q8AWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6" } ] }, { "name": "ERNST1", "type": "synonym", "evidence": [ { "id": "Q8AWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member B1", "type": "recommended", "evidence": [ { "id": "Q8AWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6/entry#names_and_taxonomy" } ] }, { "name": "Endoplasmic reticulum nucleotide sugar transporter 1", "type": "synonym", "evidence": [ { "id": "Q8AWB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane.", "evidence": [ { "database": "UniProtKB", "id": "Q8AWB6", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6#function" }, { "database": "UniProtKB", "id": "P78383", "url": "https://www.uniprot.org/uniprotkb/P78383#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8AWB6", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35B1", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6", "locus": { "chromosome": "27", "start_pos": 2954549, "end_pos": 2947713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024199", "url": "https://www.ensembl.org/id/ENSGALG00010024199" } ] } } ], "crossref": [ { "id": "Q8AWB6", "url": "https://alphafold.ebi.ac.uk/entry/Q8AWB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q8AWB6", "url": "https://www.orthodb.org/?gene=Q8AWB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "34999", "url": "https://www.rhea-db.org/rhea/34999", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q8AWB6", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8AWB6-1", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGANAGRRSRSPERLRLPVCFLGVFACYFYYGILQESITRGKYGDGARQEKFTFALSLVFIQCVINAAFAKLLIRFFDSVRADRTHSWLYAACSLSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTVLRKKYPLAKYLCVLLIVTGVALFMYKPKKGAGGDDHIFGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNVNLWSTLFLGAGILFTGELWEFLSFTERYPSIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISTMQWVGTVLVFLGLGLDAKFGKGVKKTSH", "length": 325, "header": "sp|Q8AWB6-1|S35B1_CHICK Isoform 1 of Solute carrier family 35 member B1 OS=Gallus gallus OX=9031 GN=SLC35B1 PE=2 SV=1 CANONICAL=Q8AWB6-1" }, "isoforms": [ { "isoform_ac": "Q8AWB6-1", "url": "https://www.uniprot.org/uniprotkb/Q8AWB6/entry#Q8AWB6-1", "sequence": { "sequence": "MGANAGRRSRSPERLRLPVCFLGVFACYFYYGILQESITRGKYGDGARQEKFTFALSLVFIQCVINAAFAKLLIRFFDSVRADRTHSWLYAACSLSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTVLRKKYPLAKYLCVLLIVTGVALFMYKPKKGAGGDDHIFGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNVNLWSTLFLGAGILFTGELWEFLSFTERYPSIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISTMQWVGTVLVFLGLGLDAKFGKGVKKTSH", "length": 325, "header": "sp|Q8AWB6-1|S35B1_CHICK Isoform 1 of Solute carrier family 35 member B1 OS=Gallus gallus OX=9031 GN=SLC35B1 PE=2 SV=1 CANONICAL=Q8AWB6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The nucleotide-sugar transporter family: a phylogenetic approach.", "journal": "Biochimie", "date": "2003", "authors": "Martinez-Duncker Ivan, Mollicone Rosella, Codogno Patrice, Oriol Rafael", "evidence": [ { "database": "UniProtKB", "id": "Q8AWB6", "url": 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The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_989883.2.", "evidence": [ { "database": "RefSeq", "id": "NP_989883", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989883" } ] }, { "annotation": "Induces caspases and apoptosis. 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"mass": { "chemical_mass": 99632.0, "monoisotopic_mass": 99632.0 }, "refseq": { "ac": "NP_989440", "name": "paladin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" }, "gene_names": [ { "name": "PALD1", "type": "recommended", "evidence": [ { "id": "Q8JHZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ] }, { "name": "PALD1", "type": "synonym", "evidence": [ { "id": "NP_989440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" } ] }, { "name": "PALD", "type": "synonym", "evidence": [ { "id": "NP_989440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" }, { "id": "Q8JHZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ] }, { "name": "RCJMB04_11g7", "type": "synonym", "evidence": [ { "id": "Q8JHZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ] } ], "protein_names": [ { "name": "Paladin", "type": "recommended", "evidence": [ { "id": "Q8JHZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8/entry#names_and_taxonomy" } ] }, { "name": "paladin", "type": "synonym", "evidence": [ { "id": "NP_989440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720140.1, AF411975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000230.1. On Sep 28, 2011 this sequence version replaced NP_989440.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_989440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" } ] }, { "annotation": "Paladin is an antiphosphatase that modulates the activity of specific neural crest regulatory factors during neural crest development.", "evidence": [ { "database": "RefSeq", "id": "NP_989440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" }, { "database": "PubMed", "id": "22926139", "url": "https://glygen.org/publication/PubMed/22926139" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PALD1", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8", "locus": { "chromosome": "6", "start_pos": 12254509, "end_pos": 12240374, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020588", "url": "https://www.ensembl.org/id/ENSGALG00010020588" } ] } } ], "crossref": [ { "id": "Q8JHZ8", "url": "https://alphafold.ebi.ac.uk/entry/Q8JHZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "373898", "url": "https://www.ncbi.nlm.nih.gov/gene/373898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:373898", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q8JHZ8", "url": "https://www.orthodb.org/?gene=Q8JHZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q8JHZ8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8JHZ8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8JHZ8-1", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRARFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALGSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRKLRGRWRAQSGAGWPSRGDLV", "length": 868, "header": "sp|Q8JHZ8-1|PALD_CHICK Isoform 1 of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=2 SV=2 CANONICAL=Q8JHZ8-1" }, "isoforms": [ { "isoform_ac": "Q8JHZ8-1", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8/entry#Q8JHZ8-1", "sequence": { "sequence": "MGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRARFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALGSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRKLRGRWRAQSGAGWPSRGDLV", "length": 868, "header": "sp|Q8JHZ8-1|PALD_CHICK Isoform 1 of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=2 SV=2 CANONICAL=Q8JHZ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.", "journal": "Genome Biol.", "date": "2005", "authors": "Caldwell Randolph B, Kierzek Andrzej M, Arakawa Hiroshi, Bezzubov Yuri, Zaim Jolanta, Fiedler Petra, Kutter Stefan, Blagodatski Artem, Kostovska Diyana, Koter Marek, Plachy Jiri, Carninci Piero, Hayashizaki Yoshihide, Buerstedde Jean-Marie", "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "reference": [ { "type": "PubMed", "id": "15642098", "url": "https://glygen.org/publication/PubMed/15642098" } ] }, { "title": "Paladin is an antiphosphatase that regulates neural crest cell formation and migration.", "journal": "Developmental biology", "date": "2012-11-15", "authors": "Roffers-Agarwal Julaine, Hutt Karla J, Gammill Laura S", "evidence": [ { "database": "RefSeq", "id": "NP_989440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989440" } ], "reference": [ { "type": "PubMed", "id": "22926139", "url": "https://glygen.org/publication/PubMed/22926139" } ] } ], "pathway": [ { "id": "gga:373898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373898", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q8JHZ8", "url": "https://www.uniprot.org/uniprotkb/Q8JHZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q8JHZ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 868, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q8JHZ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q8JHZ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q8QFN3-1", "uniprot_ac": "Q8QFN3", "uniprot_id": "TM121_CHICK", "mass": { "chemical_mass": 35676.0, "monoisotopic_mass": 35676.0 }, "refseq": { "ac": "NP_989870", "name": "transmembrane protein 121", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" }, "gene_names": [ { "name": "TMEM121", "type": "recommended", "evidence": [ { "id": "Q8QFN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3" } ] }, { "name": "HOLE", "type": "synonym", "evidence": [ { "id": "Q8QFN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3" } ] }, { "name": "TMEM121", "type": "synonym", "evidence": [ { "id": "NP_989870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" } ] } ], "protein_names": [ { "name": "Transmembrane protein 121", "type": "recommended", "evidence": [ { "id": "Q8QFN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3/entry#names_and_taxonomy" } ] }, { "name": "Protein hole", "type": "synonym", "evidence": [ { "id": "Q8QFN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3/entry#names_and_taxonomy" } ] }, { "name": "hole", "type": "synonym", "evidence": [ { "id": "NP_989870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" } ] }, { "name": "protein hole", "type": "synonym", "evidence": [ { "id": "NP_989870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" } ] }, { "name": "transmembrane protein 121", "type": "synonym", "evidence": [ { "id": "NP_989870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267660.8993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Oct 5, 2021 this sequence version replaced XP_015145726.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870" } ] }, { "annotation": "May play a role in MAPK signaling.", "evidence": [ { "database": "UniProtKB", "id": "Q8QFN3", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8QFN3", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM121", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3", "locus": { "chromosome": "8", "start_pos": 3882994, "end_pos": 3940881, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013137", "url": "https://www.ensembl.org/id/ENSGALG00010013137" } ] } } ], "crossref": [ { "id": "Q8QFN3", "url": "https://alphafold.ebi.ac.uk/entry/Q8QFN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054831", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054831", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395216", "url": "https://www.ncbi.nlm.nih.gov/gene/395216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395216", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395216", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QATLWEP", "url": "https://omabrowser.org/oma/group/QATLWEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q8QFN3", "url": "https://www.orthodb.org/?gene=Q8QFN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31046:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31046:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q8QFN3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8QFN3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8QFN3", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8QFN3-1", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVKTAKRGYAMILWFLYIFVLEIKLYFIFQNYKADKKNLETVARKALTLLLSICVPGLYLVLVALDSMEYIRTFRKKEDLRGRLFWVALDLLDILDIQANLWEPHRTGLPIWAEGLMFFYCYILLLILPCVSLSEISMQGEHIAPQKMMLYPVLSLVTINIVTIFIRAINMVLFQDSRVSTIFIGKNIIAIATKACTFLEYKRQVKEFPQNAIALELQQNSLSHNQTLHSTQGIPHEPSPTSEILDT", "length": 312, "header": "sp|Q8QFN3-1|TM121_CHICK Isoform 1 of Transmembrane protein 121 OS=Gallus gallus OX=9031 GN=TMEM121 PE=2 SV=1 CANONICAL=Q8QFN3-1" }, "isoforms": [ { "isoform_ac": "Q8QFN3-1", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3/entry#Q8QFN3-1", "sequence": { "sequence": "MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVKTAKRGYAMILWFLYIFVLEIKLYFIFQNYKADKKNLETVARKALTLLLSICVPGLYLVLVALDSMEYIRTFRKKEDLRGRLFWVALDLLDILDIQANLWEPHRTGLPIWAEGLMFFYCYILLLILPCVSLSEISMQGEHIAPQKMMLYPVLSLVTINIVTIFIRAINMVLFQDSRVSTIFIGKNIIAIATKACTFLEYKRQVKEFPQNAIALELQQNSLSHNQTLHSTQGIPHEPSPTSEILDT", "length": 312, "header": "sp|Q8QFN3-1|TM121_CHICK Isoform 1 of Transmembrane protein 121 OS=Gallus gallus OX=9031 GN=TMEM121 PE=2 SV=1 CANONICAL=Q8QFN3-1" }, "locus": { "chromosome": "8", "start_pos": 3883593, "end_pos": 3883379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031496.1", "url": "https://www.ensembl.org/id/ENSGALT00010031496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018395.1", "url": "https://www.ensembl.org/id/ENSGALP00010018395.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hole is a novel gene product expressed in the developing heart and brain.", "journal": "Mech. Dev.", "date": "2002", "authors": "Nesset AL, Bader DM", "evidence": [ { "database": "UniProtKB", "id": "Q8QFN3", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3" } ], "reference": [ { "type": "PubMed", "id": "12204283", "url": "https://glygen.org/publication/PubMed/12204283" } ] } ], "pathway": [ { "id": "gga:395216", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395216", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G001-1", "protein_name": "Transmembrane protein 121 isoform X2", "gene_name": "Tmem121", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRTNGSELAGQERQRAPGSWTNPAPGCAAPCRRVECRGRCSGTQQDLVPLCVGTARARAEPGPLTMVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPAPLHGPPVRPHGPSPTRDALDT", "length": 383 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZMR5-1", "protein_name": "Transmembrane protein 121", "gene_name": "Tmem121", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F5Q9-1", "protein_name": "Transmembrane protein 121", "gene_name": "tmem121aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFVFQNYKADRKSLETVARKALTLLLSVCVPGLYLVLVALDSMEYVRTFRKKEDMRGRLFWVALDLLDVLDIQANLWEPQRTGLPIWAEGLMFFYCYILLLILPCVSLSEISVQGEHVSPQKMMLYPVLSLVTINIVTILIRGVNMVLFQDSRVSTIFIGKNVVAIATKACTFLEYRRQVKEFPPQDPAGIAMEIQQNSVPHNQTLPNATTTLPEEPSPAREVIDT", "length": 316 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3MZ75-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPAPQRNSVPPPQPLHGPPGRPRGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "K7ZLB0-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPPQRNSVPPPPPLHGPPGRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80XA0-1", "protein_name": "Transmembrane protein 121", "gene_name": "Tmem121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTD3-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALSLELQPPPPQRNSVPPPPPPLHGPPGRPHMSSPTRDPLDT", "length": 319 }, "evidence": [ { "id": "Q8QFN3", "url": "https://omabrowser.org/oma/group/Q8QFN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8QFN3", "url": "https://www.uniprot.org/uniprotkb/Q8QFN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q8QFN3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q8QFN3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q8QFN3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q8QGM3-1", "uniprot_ac": "Q8QGM3", "uniprot_id": "Q8QGM3_CHICK", "mass": { "chemical_mass": 42973.0, "monoisotopic_mass": 42973.0 }, "refseq": { "ac": "NP_001026726", "name": "neuropeptide Y receptor type 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" }, "gene_names": [ { "name": "NPY4R", "type": "recommended", "evidence": [ { "id": "Q8QGM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ] }, { "name": "CH17-360D5.1", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "NPY4R2", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "NPY4R", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "PPYR1", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "Neuropeptide Y receptor Y4", "type": "synonym", "evidence": [ { "id": "Q8QGM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide Y receptor 4", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "neuropeptide Y receptor Y4", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "neuropeptide Y receptor type 4", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "name": "pancreatic polypeptide receptor 1", "type": "synonym", "evidence": [ { "id": "NP_001026726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.225480.1, SRR13267654.235188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000231.1. On or before Dec 10, 2021 this sequence version replaced XP_015143885.1, XP_426511.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ] }, { "annotation": "Expression and localization of the neuropeptide Y-Y4 receptor in the chick spleen: mRNA upregulation by high ambient temperature.", "evidence": [ { "database": "RefSeq", "id": "NP_001026726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" }, { "database": "PubMed", "id": "39121580", "url": "https://glygen.org/publication/PubMed/39121580" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPY4R", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3", "locus": { "chromosome": "6", "start_pos": 18625818, "end_pos": 18615192, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020813", "url": "https://www.ensembl.org/id/ENSGALG00010020813" } ] } } ], "crossref": [ { "id": "ENSGALG00000005923", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005923", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428955", "url": "https://www.ncbi.nlm.nih.gov/gene/428955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428955", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428955", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTVVYTM", "url": "https://omabrowser.org/oma/group/FTVVYTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q8QGM3", "url": "https://www.orthodb.org/?gene=Q8QGM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q8QGM3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8QGM3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8QGM3-1", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKTRAVHDAFPFLNNKNLSSNRSFPSHLSNQCRNVTDLTVFLATSYSLETVLGIVGNICLIAVIARQKEKTNVTNILISNLIISDLFMCLVCLPFTVVYTMMDYWIFGEVMCKMTSFTQCTSVTVSILSLVLIALERHQLIINPTGWRPSISQAYLGIGVIWTLACLMSLPFLTTSILSNDLYEQLSHIMNFSYDKAICIDSWPSEQHRLIYTTTLLLLQYCIPLFFIILCYLRIYLRLQKRKDMFEKSEYSNRAVQLRRINILLASMVAAFAVCWLPLHVFNTIVDWNYKIISPCHHNLIFSLCHLVAMASTCVNPVIYGFLNSNFKKEVKSLILSCQHNSVTASIEDYDHLPLSTMQTEVSKGSLSLNCRHNSI", "length": 377, "header": "tr|Q8QGM3-1|Q8QGM3_CHICK Isoform 1 of Neuropeptide Y receptor Y4 OS=Gallus gallus OX=9031 GN=NPY4R PE=3 SV=1 CANONICAL=Q8QGM3-1" }, "isoforms": [ { "isoform_ac": "Q8QGM3-1", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3/entry#Q8QGM3-1", "sequence": { "sequence": "MNKTRAVHDAFPFLNNKNLSSNRSFPSHLSNQCRNVTDLTVFLATSYSLETVLGIVGNICLIAVIARQKEKTNVTNILISNLIISDLFMCLVCLPFTVVYTMMDYWIFGEVMCKMTSFTQCTSVTVSILSLVLIALERHQLIINPTGWRPSISQAYLGIGVIWTLACLMSLPFLTTSILSNDLYEQLSHIMNFSYDKAICIDSWPSEQHRLIYTTTLLLLQYCIPLFFIILCYLRIYLRLQKRKDMFEKSEYSNRAVQLRRINILLASMVAAFAVCWLPLHVFNTIVDWNYKIISPCHHNLIFSLCHLVAMASTCVNPVIYGFLNSNFKKEVKSLILSCQHNSVTASIEDYDHLPLSTMQTEVSKGSLSLNCRHNSI", "length": 377, "header": "tr|Q8QGM3-1|Q8QGM3_CHICK Isoform 1 of Neuropeptide Y receptor Y4 OS=Gallus gallus OX=9031 GN=NPY4R PE=3 SV=1 CANONICAL=Q8QGM3-1" }, "locus": { "chromosome": "6", "start_pos": 18621268, "end_pos": 18620138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050336.1", "url": "https://www.ensembl.org/id/ENSGALT00010050336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029735.1", "url": "https://www.ensembl.org/id/ENSGALP00010029735.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression and localization of the neuropeptide Y-Y4 receptor in the chick spleen: mRNA upregulation by high ambient temperature.", "journal": "Neuropeptides", "date": "2024-10", "authors": "Nishimura Haruka, Elhussiny Mohamed Z, Ouchi Yoshimitsu, Haraguchi Shogo, Itoh Taichi Q, Gilbert Elizabeth R, Cline Mark A, Nishimura Shotaro, Hosaka Yoshinao Z, Takahashi Eiki, Cockrem John F, Bungo Takashi, Chowdhury Vishwajit S", "evidence": [ { "database": "RefSeq", "id": "NP_001026726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026726" } ], "reference": [ { "type": "PubMed", "id": "39121580", "url": "https://glygen.org/publication/PubMed/39121580" } ] } ], "pathway": [ { "id": "gga:428955", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428955", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LHL4-1", "protein_name": "Neuropeptide Y receptor type 4-2", "gene_name": "Npy4r2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNTSHFLASLFPGFLQGKNGTNPLDFVYNFSDGCQDSVDLLAFIITTYSIESILGILGNLCLIYVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTATYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIIHPTGWKPSIFQAYLGIVVIWFISCFLSLPFLANSILSDLFHHNHSKAVEFLEDKVVCIVFWSSDHHRLIYTTFLLLFQYSVPLVFILVCYVRIYQRLQRQRHVFHKDTCSSRVGQMKRINGTLMAMVAAFAVLWLPLHVFNTLEDWYQEAIPACHGNLIFLICHMLAMASTCVNPFIYGFLNTNFKKDIKALVLTCYCRSPRGESERLPLSTVHTDLSKGSVRLGSKSNFI", "length": 375 }, "evidence": [ { "id": "Q8QGM3", "url": "https://omabrowser.org/oma/group/Q8QGM3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P50391-1", "protein_name": "Neuropeptide Y receptor type 4", "gene_name": "NPY4R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRCLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI", "length": 375 }, "evidence": [ { "id": "Q8QGM3", "url": "https://omabrowser.org/oma/group/Q8QGM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61041-1", "protein_name": "Neuropeptide Y receptor type 4", "gene_name": "Npy4r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSHFLAPLFPGSLQGKNGTNPLDSPYNFSDGCQDSAELLAFIITTYSIETILGVLGNLCLIFVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSIFQAYLGIVVIWFVSCFLSLPFLANSTLNDLFHYNHSKVVEFLEDKVVCFVSWSSDHHRLIYTTFLLLFQYCIPLAFILVCYIRIYQRLQRQKHVFHAHACSSRAGQMKRINSMLMTMVTAFAVLWLPLHVFNTLEDWYQEAIPACHGNLIFLMCHLLAMASTCVNPFIYGFLNINFKKDIKALVLTCHCRSPRGESEHLPLSTVHTDLSKGSMRMGSKSNFI", "length": 375 }, "evidence": [ { "id": "Q8QGM3", "url": "https://omabrowser.org/oma/group/Q8QGM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63447-1", "protein_name": "Neuropeptide Y receptor type 4", "gene_name": "Npy4r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTSHLMASLSPAFLQGKNGTNPLDSLYNLSDGCQDSADLLAFIITTYSVETVLGVLGNLCLIFVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVVIWFISCFLSLPFLANSILNDLFHYNHSKVVEFLEDKVVCFVSWSSDHHRLIYTTFLLLFQYCVPLAFILVCYMRIYQRLQRQRRAFHTHTCSSRVGQMKRINGMLMAMVTAFAVLWLPLHVFNTLEDWYQEAIPACHGNLIFLMCHLFAMASTCVNPFIYGFLNINFKKDIKALVLTCRCRPPQGEPEPLPLSTVHTDLSKGSMRMGSKSNVM", "length": 375 }, "evidence": [ { "id": "Q8QGM3", "url": "https://omabrowser.org/oma/group/Q8QGM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide YY receptor activity", "id": "GO:0001601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001601", "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "pmid": "" }, { "name": "pancreatic polypeptide receptor activity", "id": "GO:0001602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001602", "evidence": [ { "database": "UniProtKB", "id": "Q8QGM3", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q8QGM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGM3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 321, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR3C2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2", "locus": { "chromosome": "4", "start_pos": 31695487, "end_pos": 31897635, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006735", "url": "https://www.ensembl.org/id/ENSGALG00010006735" } ] } } ], "crossref": [ { "id": "Q8QHI2", "url": "https://alphafold.ebi.ac.uk/entry/Q8QHI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q8QHI2", "url": "https://www.orthodb.org/?gene=Q8QHI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8QHI2-1", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FALSWRSYKHTNSQFLYFAPDLIFDEERMRQSAMFELCQGMHQISLQFVRLQLSFEEYTIMKVLLLLSTVPKDGLKSQAAFEEMRANYIKELKKMVTKCPSNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESQALKVEFPA", "length": 147, "header": "sp|Q8QHI2-1|MCR_CHICK Isoform 1 of Mineralocorticoid receptor OS=Gallus gallus OX=9031 GN=NR3C2 PE=2 SV=1 CANONICAL=Q8QHI2-1" }, "isoforms": [ { "isoform_ac": "Q8QHI2-1", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2/entry#Q8QHI2-1", "sequence": { "sequence": "FALSWRSYKHTNSQFLYFAPDLIFDEERMRQSAMFELCQGMHQISLQFVRLQLSFEEYTIMKVLLLLSTVPKDGLKSQAAFEEMRANYIKELKKMVTKCPSNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESQALKVEFPA", "length": 147, "header": "sp|Q8QHI2-1|MCR_CHICK Isoform 1 of Mineralocorticoid receptor OS=Gallus gallus OX=9031 GN=NR3C2 PE=2 SV=1 CANONICAL=Q8QHI2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "pmid": "" }, { "name": "steroid binding", "id": "GO:0005496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005496", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8QHI2", "url": "https://www.uniprot.org/uniprotkb/Q8QHI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q8QHI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 147, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q8QHI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q8QHI2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q8UVS4-1", "uniprot_ac": "Q8UVS4", "uniprot_id": "Q8UVS4_CHICK", "mass": { "chemical_mass": 26460.0, "monoisotopic_mass": 26460.0 }, "refseq": { "ac": "NP_001072971", "name": "YEATS domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" }, "gene_names": [ { "name": "YEATS4", "type": "recommended", "evidence": [ { "id": "Q8UVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ] }, { "name": "GAS41", "type": "synonym", "evidence": [ { "id": "NP_001072971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ] }, { "name": "YEATS4", "type": "synonym", "evidence": [ { "id": "NP_001072971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ] } ], "protein_names": [ { "name": "YEATS domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "Q8UVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4/entry#names_and_taxonomy" } ] }, { "name": "YEATS domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001072971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.16271.1, HAEK01138119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Dec 9, 2006 this sequence version replaced XP_001233573.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ] }, { "annotation": "Chromatin reader component of the NuA4 histone acetyltransferase (HAT) complex, a complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Specifically recognizes and binds acylated histone H3, with a preference for histone H3 diacetylated at 'Lys-18' and 'Lys-27' (H3K18ac and H3K27ac) or histone H3 diacetylated at 'Lys-14' and 'Lys-27' (H3K14ac and H3K27ac). Also able to recognize and bind crotonylated histone H3. May also recognize and bind histone H3 succinylated at 'Lys-122' (H3K122succ); additional evidences are however required to confirm this result in vivo. Plays a key role in histone variant H2AZ1/H2A.Z deposition into specific chromatin regions: recognizes and binds H3K14ac and H3K27ac on the promoters of actively transcribed genes and recruits NuA4-related complex to deposit H2AZ1/H2A.Z. H2AZ1/H2A.Z deposition is required for maintenance of embryonic stem cell.", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4#function" }, { "database": "UniProtKB", "id": "ARBA00057736", "url": "https://www.uniprot.org/uniprotkb/ARBA00057736#function" } ] }, { "annotation": "Localized the GAS41 promoter close to the 3' end of the lysozyme gene and found that Sp1 and Sp3 bind to this promoter", "evidence": [ { "database": "RefSeq", "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" }, { "database": "PubMed", "id": "20153453", "url": "https://glygen.org/publication/PubMed/20153453" } ] }, { "annotation": "Sp1 participates in recruiting Orc2 to the origin of lysozyme GAS41.", "evidence": [ { "database": "RefSeq", "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" }, { "database": "PubMed", "id": "21879882", "url": "https://glygen.org/publication/PubMed/21879882" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YEATS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4", "locus": { "chromosome": "1", "start_pos": 35556721, "end_pos": 35553787, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011992", "url": "https://www.ensembl.org/id/ENSGALG00010011992" } ] } } ], "crossref": [ { "id": "ENSGALG00000029135", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16909", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16909", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771226", "url": "https://www.ncbi.nlm.nih.gov/gene/771226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771226", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771226", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKPYHNE", "url": "https://omabrowser.org/oma/group/VKPYHNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q8UVS4", "url": "https://www.orthodb.org/?gene=Q8UVS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47573:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47573:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8866907", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8UVS4-1", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPVVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAILGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFADLEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKSEIRKLEEDDQSKDM", "length": 227, "header": "tr|Q8UVS4-1|Q8UVS4_CHICK Isoform 1 of YEATS domain-containing protein 4 OS=Gallus gallus OX=9031 GN=YEATS4 PE=1 SV=1 CANONICAL=Q8UVS4-1" }, "isoforms": [ { "isoform_ac": "Q8UVS4-1", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4/entry#Q8UVS4-1", "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPVVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAILGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFADLEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKSEIRKLEEDDQSKDM", "length": 227, "header": "tr|Q8UVS4-1|Q8UVS4_CHICK Isoform 1 of YEATS domain-containing protein 4 OS=Gallus gallus OX=9031 GN=YEATS4 PE=1 SV=1 CANONICAL=Q8UVS4-1" }, "locus": { "chromosome": "1", "start_pos": 35556304, "end_pos": 35553958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028699.1", "url": "https://www.ensembl.org/id/ENSGALT00010028699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016502.1", "url": "https://www.ensembl.org/id/ENSGALP00010016502.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sp1 and Sp3 regulate transcription of the chicken GAS41 gene.", "journal": "Biochimica et biophysica acta", "date": "2010", "authors": "H\u00fcbner Katrin, Phi-van Loc", "evidence": [ { "database": "RefSeq", "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ], "reference": [ { "type": "PubMed", "id": "20153453", "url": "https://glygen.org/publication/PubMed/20153453" } ] }, { "title": "In vivo binding of Orc2 to a region of the chicken lysozyme GAS41 origin containing multiple Sp1-binding sites.", "journal": "DNA and cell biology", "date": "2012-02", "authors": "H\u00fcbner Katrin, Phi-van Loc", "evidence": [ { "database": "RefSeq", "id": "NP_001072971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072971" } ], "reference": [ { "type": "PubMed", "id": "21879882", "url": "https://glygen.org/publication/PubMed/21879882" } ] } ], "pathway": [ { "id": "gga:771226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771226", "resource": "KEGG Pathway" }, { "id": "R-GGA-8866907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866907", "resource": "Reactome", "description": "Activation of the TFAP2 (AP-2) family of transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZ62-1", "protein_name": "YEATS domain-containing protein 4", "gene_name": "YEATS4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQTKEI", "length": 227 }, "evidence": [ { "id": "Q8UVS4", "url": "https://omabrowser.org/oma/group/Q8UVS4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95619-1", "protein_name": "YEATS domain-containing protein 4", "gene_name": "YEATS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI", "length": 227 }, "evidence": [ { "id": "Q8UVS4", "url": "https://omabrowser.org/oma/group/Q8UVS4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53930-1", "protein_name": "Protein AF-9 homolog", "gene_name": "YAF9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPTISKRIKTLSVSRPIIYGNTAKKMGSVKPPNAPAEHTHLWTIFVRGPQNEDISYFIKKVVFKLHDTYPNPVRSIEAPPFELTETGWGEFDINIKVYFVEEANEKVLNFYHRLRLHPYANPVPNSDNGNEQNTTDHNSKDAEVSSVYFDEIVFNEPNEEFFKILMSRPGNLLPSNKTDDCVYSKQLEQEEIDRIEIGIEKVDKEIDELKQKLENLVKQEAINGS", "length": 226 }, "evidence": [ { "id": "Q8UVS4", "url": "https://omabrowser.org/oma/group/Q8UVS4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9CR11-1", "protein_name": "YEATS domain-containing protein 4", "gene_name": "Yeats4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQTKDI", "length": 227 }, "evidence": [ { "id": "Q8UVS4", "url": "https://omabrowser.org/oma/group/Q8UVS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VM63-1", "protein_name": "YEATS domain-containing protein 4", "gene_name": "Gas41", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDFGGDSGGRLKGVTIVKPIVYGNIARSFGKKREEDGHTHQWKVYLKPYFNEDMSIYVKKVHFKLHESYANPNRIVVKPPYEITETGWGEFEVIIKIYFNDQSERPVTCYHILKLFQSPVVDGELSSSTTMDTKKGLVSESYEEIVFQEPTQILQHYLLLSEQSANGLLTHDTDFEEKKTKTLDNIVNVKQKVKGEIVTLKDKLKLARETISKFKAELAKVQKQPA", "length": 227 }, "evidence": [ { "id": "Q8UVS4", "url": "https://omabrowser.org/oma/group/Q8UVS4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "histone H3K18ac reader activity", "id": "GO:0140044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140044", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" }, { "name": "histone H3K27ac reader activity", "id": "GO:0140119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140119", "evidence": [ { "database": "UniProtKB", "id": "Q8UVS4", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q8UVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8UVS4" }, { "id": "PS51037", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YEATS", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 158, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q90667-1", "uniprot_ac": "Q90667", "uniprot_id": "NREP_CHICK", "mass": { "chemical_mass": 7734.0, "monoisotopic_mass": 7734.0 }, "refseq": { "ac": "NP_990722", "name": "neuronal regeneration-related protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" }, "gene_names": [ { "name": "NREP", "type": "recommended", "evidence": [ { "id": "Q90667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90667" } ] }, { "name": "3.1", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "C5ORF13", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "CZH5orf13", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "NREP", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "p311", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] } ], "protein_names": [ { "name": "Neuronal regeneration-related protein", "type": "recommended", "evidence": [ { "id": "Q90667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90667/entry#names_and_taxonomy" } ] }, { "name": "Neuronal protein 3.1", "type": "synonym", "evidence": [ { "id": "Q90667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90667/entry#names_and_taxonomy" } ] }, { "name": "P311 POU", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "Protein p311", "type": "synonym", "evidence": [ { "id": "Q90667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90667/entry#names_and_taxonomy" } ] }, { "name": "neuronal protein 3.1", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "neuronal regeneration-related protein", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] }, { "name": "protein p311", "type": "synonym", "evidence": [ { "id": "NP_990722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01059698.1, HAEL01000068.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990722", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q90667", "url": "https://www.uniprot.org/uniprotkb/Q90667" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NREP", "url": "https://www.uniprot.org/uniprotkb/Q90667", "locus": { "chromosome": "Z", "start_pos": 47133542, "end_pos": 47112375, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008177", "url": "https://www.ensembl.org/id/ENSGALG00010008177" } ] } } ], "crossref": [ { "id": "Q90667", "url": "https://alphafold.ebi.ac.uk/entry/Q90667", "database": "AlphaFoldDB", "categories": [] }, { "id": "396353", 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"end_pos": 68, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q90667-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q90667" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q90718-1", "uniprot_ac": "Q90718", "uniprot_id": "SRF_CHICK", "mass": { "chemical_mass": 39176.0, "monoisotopic_mass": 39176.0 }, "refseq": {}, "gene_names": [ { "name": "SRF", "type": "recommended", "evidence": [ { "id": "Q90718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ] } ], "protein_names": [ { "name": "Serum response factor", "type": "recommended", "evidence": [ { "id": "Q90718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90718/entry#names_and_taxonomy" } ] }, { "name": "SRF", "type": "synonym", "evidence": [ { "id": "Q90718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90718/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration.", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718#function" }, { "database": "UniProtKB", "id": "Q9JM73", "url": "https://www.uniprot.org/uniprotkb/Q9JM73#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRF", "url": "https://www.uniprot.org/uniprotkb/Q90718", "locus": { "chromosome": "3", "start_pos": 4609482, "end_pos": 4599812, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018587", "url": "https://www.ensembl.org/id/ENSGALG00010018587" } ] } } ], "crossref": [ { "id": "cd00266", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00266", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q90718", "url": "https://www.orthodb.org/?gene=Q90718", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q90718-1", "url": "https://www.uniprot.org/uniprotkb/Q90718-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PPPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDVLKPTFTVTNLPGTTSTIQTAPTTSSSMQVSSGPSFPITNYLAPVSASISPSAVTSANGTVLKTTGASAVTSGGLMQIPTGFTLMSGGTMAQQVPVQAIQVHQAPQQTSPSSDSSTDLTQTSPSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGGLAVLNAFSQTPSAMQVSHSQVQDQGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQSSSGSSLTELQXVNLDTSHNAKSD", "length": 375, "header": "sp|Q90718-1|SRF_CHICK Isoform 1 of Serum response factor OS=Gallus gallus OX=9031 GN=SRF PE=2 SV=1 CANONICAL=Q90718-1" }, "isoforms": [ { "isoform_ac": "Q90718-1", "url": "https://www.uniprot.org/uniprotkb/Q90718/entry#Q90718-1", "sequence": { "sequence": "PPPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDVLKPTFTVTNLPGTTSTIQTAPTTSSSMQVSSGPSFPITNYLAPVSASISPSAVTSANGTVLKTTGASAVTSGGLMQIPTGFTLMSGGTMAQQVPVQAIQVHQAPQQTSPSSDSSTDLTQTSPSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGGLAVLNAFSQTPSAMQVSHSQVQDQGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQSSSGSSLTELQXVNLDTSHNAKSD", "length": 375, "header": "sp|Q90718-1|SRF_CHICK Isoform 1 of Serum response factor OS=Gallus gallus OX=9031 GN=SRF PE=2 SV=1 CANONICAL=Q90718-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Avian serum response factor expression restricted primarily to muscle cell lineages is required for alpha-actin gene transcription.", "journal": "Dev. Biol.", "date": "1996", "authors": "Croissant J D, Kim J H, Eichele G, Goering L, Lough J, Prywes R, Schwartz R J", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "reference": [ { "type": "PubMed", "id": "8660892", "url": "https://glygen.org/publication/PubMed/8660892" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "serum response element binding", "id": "GO:0010736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010736", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cardiac muscle cell myoblast differentiation", "id": "GO:0060379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060379", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q90718", "url": "https://www.uniprot.org/uniprotkb/Q90718" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q90718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90718" }, { "id": "PRU00251", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00251" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MADS-box", "eco_id": "ECO_0000255", "start_pos": 10, "end_pos": 64, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q90879-1", "uniprot_ac": "Q90879", "uniprot_id": "UB2V1_CHICK", "mass": { "chemical_mass": 16335.0, "monoisotopic_mass": 16335.0 }, "refseq": { "ac": "NP_001192026", "name": "ubiquitin-conjugating enzyme E2 variant 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" }, "gene_names": [ { "name": "UBE2V1", "type": "recommended", "evidence": [ { "id": "Q90879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90879" } ] }, { "name": "CROC-1B", "type": "synonym", "evidence": [ { "id": "NP_001192026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" } ] }, { "name": "UBE2V1", "type": "synonym", "evidence": [ { "id": "NP_001192026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" } ] }, { "name": "UEV-1", "type": "synonym", "evidence": [ { "id": "NP_001192026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2 variant 1", "type": "recommended", "evidence": [ { "id": "Q90879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90879/entry#names_and_taxonomy" } ] }, { "name": "CROC-1B", "type": "synonym", "evidence": [ { "id": "Q90879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90879/entry#names_and_taxonomy" } ] }, { "name": "UEV-1", "type": "synonym", "evidence": [ { "id": "Q90879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90879/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 variant 1", "type": "synonym", "evidence": [ { "id": "NP_001192026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003787.1, L77699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000328.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001192026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192026" } ] }, { "annotation": "Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity). Together with RNF135 and UBE2N, may catalyze the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIGI to activate the downstream signaling pathway that leads to interferon beta production (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q90879", "url": "https://www.uniprot.org/uniprotkb/Q90879#function" }, { "database": "UniProtKB", "id": "Q13404", "url": "https://www.uniprot.org/uniprotkb/Q13404#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q90879", "url": "https://www.uniprot.org/uniprotkb/Q90879" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2V1", "url": "https://www.uniprot.org/uniprotkb/Q90879", "locus": { "chromosome": "20", "start_pos": 14095549, "end_pos": 14080849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014676", "url": "https://www.ensembl.org/id/ENSGALG00010014676" } ] } } ], "crossref": [ { "id": "Q90879", "url": "https://alphafold.ebi.ac.uk/entry/Q90879", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23807", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23807", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100538349", "url": "https://www.ncbi.nlm.nih.gov/gene/100538349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100538349", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100538349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" 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"Protein" ] }, { "id": "Q90879-1", "url": "https://www.uniprot.org/uniprotkb/Q90879-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 145, "header": "sp|Q90879-1|UB2V1_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 variant 1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=2 SV=2 CANONICAL=Q90879-1" }, "isoforms": [ { "isoform_ac": "Q90879-1", "url": "https://www.uniprot.org/uniprotkb/Q90879/entry#Q90879-1", "sequence": { "sequence": "MAATTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 145, "header": "sp|Q90879-1|UB2V1_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 variant 1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=2 SV=2 CANONICAL=Q90879-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "TAK1 is a ubiquitin-dependent kinase of MKK and IKK.", "journal": "Nature", "date": "2001", "authors": "Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871" } ], "reference": [ { "type": "PubMed", "id": "11460167", "url": "https://glygen.org/publication/PubMed/11460167" } ] }, { "title": "Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR .", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": 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M, Karin M", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871" } ], "reference": [ { "type": "PubMed", "id": "16306937", "url": "https://glygen.org/publication/PubMed/16306937" } ] }, { "title": "Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871" } ], "reference": [ { "type": "PubMed", "id": "17135271", "url": "https://glygen.org/publication/PubMed/17135271" } ] }, { "title": "Ubiquitin-mediated activation of TAK1 and IKK.", "journal": "Oncogene", "date": "2007", "authors": "Adhikari A, Xu M, Chen ZJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871" } ], "reference": [ { "type": "PubMed", "id": "17496917", "url": "https://glygen.org/publication/PubMed/17496917" } ] }, { "title": "Direct activation of protein kinases by unanchored polyubiquitin chains.", "journal": "Nature", "date": "2009", "authors": "Xia ZP, Sun L, Chen X, Pineda G, Jiang X, Adhikari A, Zeng W, Chen ZJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-433871", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871" } ], "reference": [ { "type": "PubMed", "id": "19675569", "url": "https://glygen.org/publication/PubMed/19675569" } ] } ], "pathway": [ { "id": "gga:100538349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100538349", "resource": "KEGG Pathway" }, { "id": "R-GGA-433871", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433871", "resource": "Reactome", "description": "TRAF6 mediated induction of proinflammatory cytokines" } ], 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The reference sequence was derived from JAENSK010000037.1. On Nov 25, 2021 this sequence version replaced NP_989470.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989470" } ] }, { "annotation": "During limb development, distal mesenchyme cells intrinsically time Hoxa13 expression, cell cycle parameters and the duration of the overlying apical ectodermal ridge. 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"MFLYDNSLDEINKNMDGFHAGSNFAAAAAANPCRNLMAHPAPLAAPSAAAYTSSEAPAAGMAEPAVKQCSPCSAAVQSSSGAALPYGYFGSGYYPCRMTHHNAIKSCAQPASTFADKYMDTSVSGEEFTSRAKEFAFYQGYAAGPYQPVPGYLDVPVVPTIGGPGEPRHDSLLPMDSYQPWAITNGWNGQVYCPKEQSQPPHLWKSTLPDVVSHPSDANSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTTS", "length": 290, "header": "sp|Q90X25-1|HXA13_CHICK Isoform 1 of Homeobox protein Hox-A13 OS=Gallus gallus OX=9031 GN=HOXA13 PE=2 SV=1 CANONICAL=Q90X25-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hoxa-11 and Hoxa-13 are involved in repression of MyoD during limb muscle development.", "journal": "Development, growth & differentiation", "date": "2003", "authors": "Yamamoto Masakazu, Kuroiwa Atsushi", "evidence": [ { "database": "RefSeq", "id": "NP_989470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989470" } ], "reference": [ { "type": "PubMed", "id": "14706073", "url": 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Transcript exon combination :: SRR13267648.14705.1, SRR13267655.115693.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992453, SAMN08016671 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000043.1. On Nov 4, 2021 this sequence version replaced NP_989529.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989529" } ] }, { "annotation": "May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q98T89", "url": "https://www.uniprot.org/uniprotkb/Q98T89#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98T89", "url": "https://www.uniprot.org/uniprotkb/Q98T89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TWSG1", "url": "https://www.uniprot.org/uniprotkb/Q98T89", "locus": { "chromosome": "2", "start_pos": 98184517, "end_pos": 98202734, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001836", "url": "https://www.ensembl.org/id/ENSGALG00010001836" } ] } } ], "crossref": [ { "id": "Q98T89", "url": "https://alphafold.ebi.ac.uk/entry/Q98T89", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q98TF7-1", "uniprot_ac": "Q98TF7", "uniprot_id": "RL35_CHICK", "mass": { "chemical_mass": 14551.0, "monoisotopic_mass": 14551.0 }, "refseq": { "ac": "NP_989604", "name": "large ribosomal subunit protein uL29", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604" }, "gene_names": [ { "name": "RPL35", "type": "recommended", "evidence": [ { "id": "Q98TF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ] }, { "name": "RPL35", "type": "synonym", "evidence": [ { "id": "NP_989604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL29", "type": "recommended", "evidence": [ { "id": "Q98TF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF7/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L35", "type": "synonym", "evidence": [ { "id": "NP_989604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604" }, { "id": "Q98TF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TF7/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein uL29", "type": "synonym", "evidence": [ { "id": "NP_989604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01013691.1, HAEK01138342.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7#function" }, { "database": "UniProtKB", "id": "P42766", "url": "https://www.uniprot.org/uniprotkb/P42766#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL35", "url": "https://www.uniprot.org/uniprotkb/Q98TF7", "locus": { "chromosome": "17", "start_pos": 10131955, "end_pos": 10135058, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027733", "url": "https://www.ensembl.org/id/ENSGALG00010027733" } ] } } ], "crossref": [ { "id": "Q98TF7", "url": "https://alphafold.ebi.ac.uk/entry/Q98TF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035677", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035677", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00427", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00427", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374133", "url": "https://www.ncbi.nlm.nih.gov/gene/374133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374133", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374133", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMNQKAR", "url": "https://omabrowser.org/oma/group/VMNQKAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q98TF7", "url": "https://www.orthodb.org/?gene=Q98TF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45722", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45722", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45722:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45722:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q98TF7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q98TF7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98TF7-1", "url": "https://www.uniprot.org/uniprotkb/Q98TF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPVRKYAIKA", "length": 123, "header": "sp|Q98TF7-1|RL35_CHICK Isoform 1 of Large ribosomal subunit protein uL29 OS=Gallus gallus OX=9031 GN=RPL35 PE=1 SV=3 CANONICAL=Q98TF7-1" }, "isoforms": [ { "isoform_ac": "Q98TF7-1", "url": "https://www.uniprot.org/uniprotkb/Q98TF7/entry#Q98TF7-1", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPVRKYAIKA", "length": 123, "header": "sp|Q98TF7-1|RL35_CHICK Isoform 1 of Large ribosomal subunit protein uL29 OS=Gallus gallus OX=9031 GN=RPL35 PE=1 SV=3 CANONICAL=Q98TF7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.", "journal": "Genomics", "date": "2001", "authors": "Uechi T, Tanaka T, Kenmochi N", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "reference": [ { "type": "PubMed", "id": "11401437", "url": "https://glygen.org/publication/PubMed/11401437" } ] } ], "pathway": [ { "id": "gga:374133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374133", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HZI1-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "Rpl35", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0CX84-1", "protein_name": "Large ribosomal subunit protein uL29A", "gene_name": "RPL35A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX85-1", "protein_name": "Large ribosomal subunit protein uL29B", "gene_name": "RPL35B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P17078-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "Rpl35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P42766-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "RPL35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q29361-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "RPL35", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKFAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3MHM7-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "RPL35", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLEDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54J23-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "rpl35", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAEKTKAFELRTKNKTQLLEHLKELRTELSSLRVAQVKSPNPSKLAKIGTVRKAIARVLTVFNQTQKNHLRAVYSKKSSSKIPTDLRYKKTRAIRRRLTNKQSKVVTLRVSKTATNFPQRVFAVKA", "length": 126 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6ZWV7-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "Rpl35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLRKYAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8JHJ1-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "rpl35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAIRRQLTKHEENLMTKKMQRKSRLYSIRKFAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9SF53-1", "protein_name": "Large ribosomal subunit protein uL29z", "gene_name": "RPL35A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARIKVHELREKSKSDLQNQLKELKAELALLRVAKVTGGAPNKLSKIKVVRKSIAQVLTVSSQKQKSALREAYKNKKLLPLDLRPKKTRAIRRRLTKHQASLKTEREKKKEMYFPIRKYAIKV", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W499-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "RpL35", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQRKFAVKA", "length": 123 }, "evidence": [ { "id": "Q98TF7", "url": "https://omabrowser.org/oma/group/Q98TF7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "Q98TF7", "url": "https://www.uniprot.org/uniprotkb/Q98TF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q98TF7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5#function" }, { "database": "UniProtKB", "id": "Q9EPN1", "url": "https://www.uniprot.org/uniprotkb/Q9EPN1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NBEA", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5", "locus": { "chromosome": "1", "start_pos": 172875165, "end_pos": 173345883, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006516", "url": "https://www.ensembl.org/id/ENSGALG00010006516" } ] } } ], "crossref": [ { "id": "Q9DDD5", "url": "https://alphafold.ebi.ac.uk/entry/Q9DDD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR031570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "Q9DDD5", "url": "https://www.orthodb.org/?gene=Q9DDD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9DDD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PKNSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMATKVSDDVLGSAERPGGGVHVEVHDLLVDIKAERVEATEVKLDDMDLSPETLVTGENGALVEVESLLDNVYSAAVEKLQNSVHGSVGIIKKNEEKDGGPLITLADEKDEPSTNSTSFLFDKIPSQEEKLLPDLSISHISIPNVQDTQMHLGVNDDLGLLAHMTGGVDITSTSSIIEDKEFKIHTNSVGMSSIFERELASLFKGLEYAEMTATTPETEFFCSKTVPNVDAGSIISVTERFVDGKEAGKEIRKIQTTTTTQAVQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTNMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRERVNKTSLISSKAQDALQGVTASAATKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETARSGSQAGRNIRQEINSPTSTETPAVFPENIKDKETPTPVEDIQLESSIPHTDSGIGEEQMPNILNGTDLETSTGPDAMSELLSTLSSEVKKSQESLTESPSEILK", "length": 793, "header": "sp|Q9DDD5-1|NBEA_CHICK Isoform 1 of Neurobeachin OS=Gallus gallus OX=9031 GN=NBEA PE=2 SV=1 CANONICAL=Q9DDD5-1" }, "isoforms": [ { "isoform_ac": "Q9DDD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5/entry#Q9DDD5-1", "sequence": { "sequence": "PKNSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKKGKKGNVSTISGLSSQTTGAKGGMEIREIEDLSQSQSPESETDYPVSTDTRDLLMATKVSDDVLGSAERPGGGVHVEVHDLLVDIKAERVEATEVKLDDMDLSPETLVTGENGALVEVESLLDNVYSAAVEKLQNSVHGSVGIIKKNEEKDGGPLITLADEKDEPSTNSTSFLFDKIPSQEEKLLPDLSISHISIPNVQDTQMHLGVNDDLGLLAHMTGGVDITSTSSIIEDKEFKIHTNSVGMSSIFERELASLFKGLEYAEMTATTPETEFFCSKTVPNVDAGSIISVTERFVDGKEAGKEIRKIQTTTTTQAVQGRSVTQQDRDLRVDLGFRGMPMTEEQRRQFSPGPRTNMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQRERVNKTSLISSKAQDALQGVTASAATKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEPQRETARSGSQAGRNIRQEINSPTSTETPAVFPENIKDKETPTPVEDIQLESSIPHTDSGIGEEQMPNILNGTDLETSTGPDAMSELLSTLSSEVKKSQESLTESPSEILK", "length": 793, "header": "sp|Q9DDD5-1|NBEA_CHICK Isoform 1 of Neurobeachin OS=Gallus gallus OX=9031 GN=NBEA PE=2 SV=1 CANONICAL=Q9DDD5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 725, "start_aa": "Thr", "end_pos": 725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr725", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Neurobeachin: a protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic.", "journal": "J. Neurosci.", "date": "2000", "authors": "Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW", "evidence": [ { "database": "UniProtKB", "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5" } ], "reference": [ { "type": "PubMed", "id": "11102458", "url": "https://glygen.org/publication/PubMed/11102458" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9DDD5", "url": "https://www.uniprot.org/uniprotkb/Q9DDD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9DDD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 793, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9DDD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9DDD5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 725 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q9DE13-1", "uniprot_ac": "Q9DE13", "uniprot_id": "BAZ2B_CHICK", "mass": { "chemical_mass": 236141.0, "monoisotopic_mass": 236141.0 }, "refseq": {}, "gene_names": [ { "name": "BAZ2B", "type": "recommended", "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ] } ], "protein_names": [ { "name": "Bromodomain adjacent to zinc finger domain protein 2B", "type": "recommended", "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13/entry#names_and_taxonomy" } ] }, { "name": "Extracellular matrix protein F22", "type": "synonym", "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair (By similarity). Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template (By similarity). The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex (By similarity). Chromatin reader protein (By similarity). Represses the expression of mitochondrial function-related genes, perhaps by transcriptional regulation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13#function" }, { "database": "UniProtKB", "id": "A2AUY4", "url": "https://www.uniprot.org/uniprotkb/A2AUY4#function" }, { "database": "UniProtKB", "id": "Q9UIF8", "url": "https://www.uniprot.org/uniprotkb/Q9UIF8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BAZ2B", "url": "https://www.uniprot.org/uniprotkb/Q9DE13", "locus": { "chromosome": "7", "start_pos": 36165488, "end_pos": 36273093, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010965", "url": "https://www.ensembl.org/id/ENSGALG00010010965" } ] } } ], "crossref": [ { "id": "Q9DE13", "url": "https://alphafold.ebi.ac.uk/entry/Q9DE13", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05503", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05503", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15630", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15630", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395400", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9DE13", "url": "https://www.orthodb.org/?gene=Q9DE13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9DE13", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9DE13", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9DE13-1", "url": "https://www.uniprot.org/uniprotkb/Q9DE13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGERLTSSSVSSTAAASSPVSSTPSVASAVSKSGLTTGAASLSSTINTGEWWRTADSHSRSGAAFFPPLLGPPLLGISPLFAPPAQNHDSTPFHPRTTGKNNRGSLEKGINGSLNGNSTTAASAISTSVLSTSIATSAGQVKVVTSGAGGRKYNQEQNKVQLLDTRADKIKDKKPRKKAVESSSNSDSDSGSSSDTSSEGISSSDSDDLEEDEEEEEDQSAEESEDDESDSENEAHHENKNKVLMHSGVKDMKTDGQKAHEKSQEKRTHQQIPLVSDSQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVPNVKPLSLVHQTKKEAYLKIIVPPPDLLKAGNKNTSEESIPLISDVRSKREQYKQTFPAAQLKKQESSKNLKKVIASLSSSKPTSCSPAHQKLTSLENNHSNPFLTNALLGNHQPNGVIQSVIQEVPLALTTKQKSQTKINESVAIASSTPFSLPVNLSACGKKTTGNRTLVVPSTSPVLPGSGKDKPVSNNAVNAVKTQHCLPSAKLVVEQFRGVDSDAPSSKESDDSNDDDDDDEDEDEDDEDDDSDDSQSESDSNSESDTDGSEDEDDEDDKDQDESDTDTEGEKTPLKLKKTGSSIKSSSIGPVAHSTPLNLQVAKTPSSAPSALCPETQPAVFLGTTPSTLTPSSHCGISKRRRVTDERELRVPLEYGWQRETRIRNFGGRLQGEVAYFAPCGKKLRQYPEVVKGVQWCLLKEEEVVPCIRAMEGRRGRPPNPDRQHSREESRMRRRKGRPPNVGSTEFLDSTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARAAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKALPELPRIPGLVLSGSTFSDCLMIVQFLRNFGKVLGFDVNTDVPSLSTLQEGLLNIGDSRGEVQDLLVKLVTAAVCDPGLVTGYKAKTILGEHLLNVGINRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKAAVLAFLVNELACSKSVVSEIDKNIDYMSNLRRDKWMVEGKLRNLRIIHAKKTGKRDATGGGEVGEEPHSLETPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKAEVCEDEDDGDQTVSVEELEKQIEKLTKQQSQYRKKLFEASHCLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEKEKLKKVESIHIKEEVFEISEEKISCLNTTRCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPECDVMPQKPNGGAANGCTPSYQNTSQNSLCSLQPSVSQSSSEKSDSSNLFSPTASGTGKFYSSPLIPSDQLLKTLTEKNRQWFSLLPRVPCDDMSVTHVDTPATTSLTPQSHPPSKSPSPVPSPLLGSTSAQSPMGLSPFAMPPLQQMKPGLPVMGLQFCGWPTGVLTSNVQFSSPLPTLGSGLGLSEGNGNSFLTSSVPTSKSESPALQTEKVAFATCTAVEVAKPVDHPNPKPIPEEMQYGWWRITDPEDLKSLHKVLHLRGIREKALQKQIQKHMDYITLACIKNKDVAIIDINENEDNQVTRDVVENWSVEEQAMEVDLAILQQVEDLERRVASASLQVKGWLCPEPASEREDLVYHEHKSIIRLHKKHDGDSAGGGEGSTSSLERKNDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSISGDGDGTEEDIAPGLRVWRKALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKLKKLQIKGKKSNEQKRGRKLPGDTEDEDSATTSTSLKRGKTEPKKRKMDESVSVSQGKQENFTAIKKPKRDDSKDLAICSMILSELETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIRDKLTSGQYPNVEAFSLDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTEIFKLS", "length": 2130, "header": "sp|Q9DE13-1|BAZ2B_CHICK Isoform 1 of Bromodomain adjacent to zinc finger domain protein 2B OS=Gallus gallus OX=9031 GN=BAZ2B PE=2 SV=1 CANONICAL=Q9DE13-1" }, "isoforms": [ { "isoform_ac": "Q9DE13-1", "url": "https://www.uniprot.org/uniprotkb/Q9DE13/entry#Q9DE13-1", "sequence": { "sequence": "MESGERLTSSSVSSTAAASSPVSSTPSVASAVSKSGLTTGAASLSSTINTGEWWRTADSHSRSGAAFFPPLLGPPLLGISPLFAPPAQNHDSTPFHPRTTGKNNRGSLEKGINGSLNGNSTTAASAISTSVLSTSIATSAGQVKVVTSGAGGRKYNQEQNKVQLLDTRADKIKDKKPRKKAVESSSNSDSDSGSSSDTSSEGISSSDSDDLEEDEEEEEDQSAEESEDDESDSENEAHHENKNKVLMHSGVKDMKTDGQKAHEKSQEKRTHQQIPLVSDSQTHSSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVPNVKPLSLVHQTKKEAYLKIIVPPPDLLKAGNKNTSEESIPLISDVRSKREQYKQTFPAAQLKKQESSKNLKKVIASLSSSKPTSCSPAHQKLTSLENNHSNPFLTNALLGNHQPNGVIQSVIQEVPLALTTKQKSQTKINESVAIASSTPFSLPVNLSACGKKTTGNRTLVVPSTSPVLPGSGKDKPVSNNAVNAVKTQHCLPSAKLVVEQFRGVDSDAPSSKESDDSNDDDDDDEDEDEDDEDDDSDDSQSESDSNSESDTDGSEDEDDEDDKDQDESDTDTEGEKTPLKLKKTGSSIKSSSIGPVAHSTPLNLQVAKTPSSAPSALCPETQPAVFLGTTPSTLTPSSHCGISKRRRVTDERELRVPLEYGWQRETRIRNFGGRLQGEVAYFAPCGKKLRQYPEVVKGVQWCLLKEEEVVPCIRAMEGRRGRPPNPDRQHSREESRMRRRKGRPPNVGSTEFLDSTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARAAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQELERHRLDMERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKALPELPRIPGLVLSGSTFSDCLMIVQFLRNFGKVLGFDVNTDVPSLSTLQEGLLNIGDSRGEVQDLLVKLVTAAVCDPGLVTGYKAKTILGEHLLNVGINRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKAAVLAFLVNELACSKSVVSEIDKNIDYMSNLRRDKWMVEGKLRNLRIIHAKKTGKRDATGGGEVGEEPHSLETPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDDEDEEDKEDKKGKKAEVCEDEDDGDQTVSVEELEKQIEKLTKQQSQYRKKLFEASHCLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEKEKLKKVESIHIKEEVFEISEEKISCLNTTRCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPECDVMPQKPNGGAANGCTPSYQNTSQNSLCSLQPSVSQSSSEKSDSSNLFSPTASGTGKFYSSPLIPSDQLLKTLTEKNRQWFSLLPRVPCDDMSVTHVDTPATTSLTPQSHPPSKSPSPVPSPLLGSTSAQSPMGLSPFAMPPLQQMKPGLPVMGLQFCGWPTGVLTSNVQFSSPLPTLGSGLGLSEGNGNSFLTSSVPTSKSESPALQTEKVAFATCTAVEVAKPVDHPNPKPIPEEMQYGWWRITDPEDLKSLHKVLHLRGIREKALQKQIQKHMDYITLACIKNKDVAIIDINENEDNQVTRDVVENWSVEEQAMEVDLAILQQVEDLERRVASASLQVKGWLCPEPASEREDLVYHEHKSIIRLHKKHDGDSAGGGEGSTSSLERKNDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSISGDGDGTEEDIAPGLRVWRKALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKLKKLQIKGKKSNEQKRGRKLPGDTEDEDSATTSTSLKRGKTEPKKRKMDESVSVSQGKQENFTAIKKPKRDDSKDLAICSMILSELETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIRDKLTSGQYPNVEAFSLDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTEIFKLS", "length": 2130, "header": "sp|Q9DE13-1|BAZ2B_CHICK Isoform 1 of Bromodomain adjacent to zinc finger domain protein 2B OS=Gallus gallus OX=9031 GN=BAZ2B PE=2 SV=1 CANONICAL=Q9DE13-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1208, "start_aa": "Thr", "end_pos": 1208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1208", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395400", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9DE13", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1363, "end_pos": 1365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1714, "end_pos": 1716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2013, "end_pos": 2015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9DE13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 2130, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9DE13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9DE13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" }, { "id": "PRU00035", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000255", "start_pos": 2022, "end_pos": 2126, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" }, { "id": "PRU00063", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00063" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDT", "eco_id": "ECO_0000255", "start_pos": 1010, "end_pos": 1075, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9DE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9DE13" }, { "id": "PRU00338", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00338" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBD", "eco_id": "ECO_0000255", "start_pos": 687, "end_pos": 762, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 25, 1208 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 119, "end_pos": 121 }, { "start_pos": 1363, "end_pos": 1365 }, { "start_pos": 1426, "end_pos": 1428 }, { "start_pos": 1714, "end_pos": 1716 }, { "start_pos": 2013, "end_pos": 2015 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 495, "end_pos": 497 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q9I870-1", "uniprot_ac": "Q9I870", "uniprot_id": "Q9I870_CHICK", "mass": { "chemical_mass": 13933.0, "monoisotopic_mass": 13933.0 }, "refseq": { "ac": "NP_990019", "name": "histidine triad nucleotide binding protein W", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, "gene_names": [ { "name": "LOC121108205", "type": "recommended", "evidence": [ { "id": "Q9I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ] }, { "name": "ASW", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "HIM", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "HINTLA1", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "HINTW", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "PKCIW", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "WPKCI-8", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "Wpkci-7", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "Wpkci", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] } ], "protein_names": [ { "name": "Histidine triad nucleotide binding protein W", "type": "synonym", "evidence": [ { "id": "Q9I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I870/entry#names_and_taxonomy" } ] }, { "name": "W-linked protein kinase C inhibitor", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "avian sex-specific W-linked", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "histidine triad missing", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "name": "histidine triad nucleotide binding protein W", "type": "synonym", "evidence": [ { "id": "NP_990019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: AF285875.1, AB033880.1 [ECO:0000331] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000512.1. On Aug 30, 2004 this sequence version replaced XP_429243.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ] }, { "annotation": "Female (ZW) gonads over-expressing HINTW also developed normally, with normal ovarian structure and left/right asymmetry", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "19123127", "url": "https://glygen.org/publication/PubMed/19123127" } ] }, { "annotation": "HINT1 and wPKCI are paralogs but appear not to have the same function. WPKCI is tandemly repeated with partial CR1 repeat sequences between gene copies. Female specific expression of WPKCI found in all Carinate birds examined.", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "11029061", "url": "https://glygen.org/publication/PubMed/11029061" } ] }, { "annotation": "HINTW (WPKCI, ASW) shows strong postive selection for new functional properties in female Galliforms. Note that the functional histadine motif is missing in Galliform HINTW, compared to HINTZ (PKCI).", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "12949135", "url": "https://glygen.org/publication/PubMed/12949135" } ] }, { "annotation": "Role and function of the Hintw in early sex differentiation in chicken (Gallus gallus) embryo.", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "34153202", "url": "https://glygen.org/publication/PubMed/34153202" } ] }, { "annotation": "The authors' analyze gene conversion rates in Galliform HINTW (WPKCI, ASW)genes to examine evolution of this female-specific gametolog. Chicken, turkey, quail and pheasant HINTW genes are examined.", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "15972846", "url": "https://glygen.org/publication/PubMed/15972846" } ] }, { "annotation": "WPKCI (ASW, HINTW) is differentially expressed on the female genital ridge. Shows female specific expression for all neognathae tested. ORF for WPKCI not identified in zebra finch.", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" }, { "database": "PubMed", "id": "11180828", "url": "https://glygen.org/publication/PubMed/11180828" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121108205", "url": "https://www.uniprot.org/uniprotkb/Q9I870", "locus": {} } ], "crossref": [ { "id": "395423", "url": "https://www.ncbi.nlm.nih.gov/gene/395423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395423", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLTYNCL", "url": "https://omabrowser.org/oma/group/PLTYNCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9I870", "url": "https://www.orthodb.org/?gene=Q9I870", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9I870-1", "url": "https://www.uniprot.org/uniprotkb/Q9I870-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGIVRSPAAWRGGAALLGKVARQEFSANVIREEEPLWTRSALRSMIFHRKLLRFFLAAPQKAVVGLSGAEDCGAPLLGRLMIVGEKCAASLGLTDGFRMAVRYPPSVPSDYRARLCILGGRQLGQPPG", "length": 130, "header": "tr|Q9I870-1|Q9I870_CHICK Isoform 1 of Histidine triad nucleotide binding protein W OS=Gallus gallus OX=9031 GN=LOC121108205 PE=4 SV=1 CANONICAL=Q9I870-1" }, "isoforms": [ { "isoform_ac": "Q9I870-1", "url": "https://www.uniprot.org/uniprotkb/Q9I870/entry#Q9I870-1", "sequence": { "sequence": "MAGGIVRSPAAWRGGAALLGKVARQEFSANVIREEEPLWTRSALRSMIFHRKLLRFFLAAPQKAVVGLSGAEDCGAPLLGRLMIVGEKCAASLGLTDGFRMAVRYPPSVPSDYRARLCILGGRQLGQPPG", "length": 130, "header": "tr|Q9I870-1|Q9I870_CHICK Isoform 1 of Histidine triad nucleotide binding protein W OS=Gallus gallus OX=9031 GN=LOC121108205 PE=4 SV=1 CANONICAL=Q9I870-1" }, "locus": { "chromosome": "W", "start_pos": 2915292, "end_pos": 2913096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028707.1", "url": "https://www.ensembl.org/id/ENSGALT00010028707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016510.1", "url": "https://www.ensembl.org/id/ENSGALP00010016510.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Wpkci, encoding an altered form of PKCI, is conserved widely on the avian W chromosome and expressed in early female embryos: implication of its role in female sex determination.", "journal": "Molecular biology of the cell", "date": "2000-10", "authors": "Hori T, Asakawa S, Itoh Y, Shimizu N, Mizuno S", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "11029061", "url": "https://glygen.org/publication/PubMed/11029061" } ] }, { "title": "ASW: a gene with conserved avian W-linkage and female specific expression in chick embryonic gonad.", "journal": "Development genes and evolution", "date": "2000-05", "authors": "O'Neill M, Binder M, Smith C, Andrews J, Reed K, Smith M, Millar C, Lambert D, Sinclair A", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "11180828", "url": "https://glygen.org/publication/PubMed/11180828" } ] }, { "title": "Adaptive molecular evolution of HINTW, a female-specific gene in birds.", "journal": "Molecular biology and evolution", "date": "2004-02", "authors": "Ceplitis Helene, Ellegren Hans", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "12949135", "url": "https://glygen.org/publication/PubMed/12949135" } ] }, { "title": "Gene conversion drives the evolution of HINTW, an ampliconic gene on the female-specific avian W chromosome.", "journal": "Molecular biology and evolution", "date": "2005-10", "authors": "Backstr\u00f6m Niclas, Ceplitis Helene, Berlin Sofia, Ellegren Hans", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "15972846", "url": "https://glygen.org/publication/PubMed/15972846" } ] }, { "title": "Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination.", "journal": "The International journal of developmental biology", "date": "2009", "authors": "Smith Craig A, Roeszler Kelly N, Sinclair Andrew H", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "19123127", "url": "https://glygen.org/publication/PubMed/19123127" } ] }, { "title": "Role and function of the Hintw in early sex differentiation in chicken (Gallus gallus) embryo.", "journal": "Animal biotechnology", "date": "2023-02", "authors": "Sun Changhua, Jin Kai, Zhou Jing, Zuo Qisheng, Song Jiuzhou, Yani Zhang, Chen Guohong, Li Bichun", "evidence": [ { "database": "RefSeq", "id": "NP_990019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990019" } ], "reference": [ { "type": "PubMed", "id": "34153202", "url": "https://glygen.org/publication/PubMed/34153202" } ] } ], "pathway": [ { "id": "gga:395423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395423", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "purine ribonucleotide catabolic process", "id": "GO:0009154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009154", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" }, { "name": "female sex differentiation", "id": "GO:0046660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046660", "evidence": [ { "database": "UniProtKB", "id": "Q9I870", "url": "https://www.uniprot.org/uniprotkb/Q9I870" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"OTOR_CHICK", "mass": { "chemical_mass": 15177.0, "monoisotopic_mass": 15177.0 }, "refseq": { "ac": "NP_990063", "name": "otoraplin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" }, "gene_names": [ { "name": "OTOR", "type": "recommended", "evidence": [ { "id": "Q9I8P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I8P6" } ] }, { "name": "CTAGE1", "type": "synonym", "evidence": [ { "id": "NP_990063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" } ] }, { "name": "OTOR", "type": "synonym", "evidence": [ { "id": "NP_990063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" } ] } ], "protein_names": [ { "name": "Otoraplin", "type": "recommended", "evidence": [ { "id": "Q9I8P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I8P6/entry#names_and_taxonomy" } ] }, { "name": "otoraplin precursor", "type": "synonym", "evidence": [ { "id": "NP_990063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" } ] }, { "name": "otoraplin", "type": "synonym", "evidence": [ { "id": "NP_990063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF233518.1, SRR12888517.15238.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000060.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9I8P6", "url": "https://www.uniprot.org/uniprotkb/Q9I8P6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OTOR", "url": "https://www.uniprot.org/uniprotkb/Q9I8P6", "locus": {} } ], "crossref": [ { "id": "Q9I8P6", "url": "https://alphafold.ebi.ac.uk/entry/Q9I8P6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008732", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008732", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11891", "url": 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Pathway" ] }, { "id": "LCADDDC", "url": "https://omabrowser.org/oma/group/LCADDDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9I8P6", "url": "https://www.orthodb.org/?gene=Q9I8P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47146:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47146:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9I8P6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9I8P6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990063", 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CANONICAL=Q9I8P6-1" }, "locus": { "chromosome": "3", "start_pos": 5841959, "end_pos": 5837049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046607.1", "url": "https://www.ensembl.org/id/ENSGALT00010046607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027758.1", "url": "https://www.ensembl.org/id/ENSGALP00010027758.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping.", "journal": "Genomics", "date": "2000", "authors": "Robertson N G, Heller S, Lin J S, Resendes B L, Weremowicz S, Denis C S, Bell A M, Hudspeth A J, Morton C C", "evidence": [ { "database": "UniProtKB", "id": "Q9I8P6", "url": "https://www.uniprot.org/uniprotkb/Q9I8P6" } ], "reference": [ { "type": "PubMed", "id": "10873378", "url": "https://glygen.org/publication/PubMed/10873378" } ] } ], "pathway": [ { 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"recommended", "evidence": [ { "id": "Q9I9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9J6" } ] }, { "name": "C11orf58", "type": "synonym", "evidence": [ { "id": "NP_990089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990089" } ] }, { "name": "C5H11orf58", "type": "synonym", "evidence": [ { "id": "NP_990089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990089" } ] }, { "name": "SMAP", "type": "synonym", "evidence": [ { "id": "NP_990089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990089" } ] } ], "protein_names": [ { "name": "Small acidic protein", "type": "recommended", "evidence": [ { "id": "Q9I9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9J6/entry#names_and_taxonomy" } ] }, { "name": "chromosome 5 C11orf58 homolog", "type": "synonym", "evidence": [ { "id": "NP_990089", "database": "RefSeq", "url": 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The reference sequence was derived from JAENSK010000214.1. 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q9PRG9-1", "uniprot_ac": "Q9PRG9", "uniprot_id": "Q9PRG9_CHICK", "mass": { "chemical_mass": 42057.0, "monoisotopic_mass": 42057.0 }, "refseq": { "ac": "NP_990209", "name": "pepsin A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" }, "gene_names": [ { "name": "PGA5", "type": "recommended", "evidence": [ { "id": "Q9PRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" } ] }, { "name": "CPGA", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "PGA3", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "PGA5", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "PGA", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] } ], "protein_names": [ { "name": "pepsin A", "type": "recommended", "evidence": [ { "id": "Q9PRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9/entry#names_and_taxonomy" } ] }, { "name": "3.4.23.1", "type": "synonym", "evidence": [ { "id": "Q9PRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9/entry#names_and_taxonomy" } ] }, { "name": "Chicken pepsinogen A", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "pepsin A precursor", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "pepsin A", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "pepsinogen 5, group I (pepsinogen A)", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "pepsinogen A", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "name": "pepsinogens A", "type": "synonym", "evidence": [ { "id": "NP_990209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB025281.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992482 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB025281.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990209" } ] }, { "annotation": "Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.", "evidence": [ { "database": "UniProtKB", "id": "Q9PRG9", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9#function" }, { "database": "UniProtKB", "id": "ARBA00002318", "url": "https://www.uniprot.org/uniprotkb/ARBA00002318#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9PRG9", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGA5", "url": 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"MKLLLLLSLVALAQCSIHRVPLKKGKSLRKQLKDHGLLEDFLKKHPYNPASKYHPVLTATESYEPMTNYMDASYYGTISIGTPQQDFTVIFDTGSSNLWVPSIYCKSSACSNHKRFDPSKSSTYVSTNETVYIAYGTGSMSGILGYDTVAVSSIDVQNQIFGLSETEPGSFFYYCNFDGILGLAFPSISSSGATPVFDNMMSQHLVAQDLFSVYLSKDGETGSFVLFGGIDPNYTTKGIYWVPLSAETYWQITMDRVTVGNKYVACFFTCQAIVDTGTSLLVMPQGAYNRIIKDLGVSSDGEISCDDISKLPDVTFHINGHAFTLPASAYVLNEDGSCMLGFENMGTPTELGEQWILGDVFIREYYVIFDRANNKVGLSPLS", "length": 382, "header": "tr|Q9PRG9-1|Q9PRG9_CHICK Isoform 1 of pepsin A OS=Gallus gallus OX=9031 GN=PGA5 PE=3 SV=1 CANONICAL=Q9PRG9-1" }, "isoforms": [ { "isoform_ac": "Q9PRG9-1", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9/entry#Q9PRG9-1", "sequence": { "sequence": "MKLLLLLSLVALAQCSIHRVPLKKGKSLRKQLKDHGLLEDFLKKHPYNPASKYHPVLTATESYEPMTNYMDASYYGTISIGTPQQDFTVIFDTGSSNLWVPSIYCKSSACSNHKRFDPSKSSTYVSTNETVYIAYGTGSMSGILGYDTVAVSSIDVQNQIFGLSETEPGSFFYYCNFDGILGLAFPSISSSGATPVFDNMMSQHLVAQDLFSVYLSKDGETGSFVLFGGIDPNYTTKGIYWVPLSAETYWQITMDRVTVGNKYVACFFTCQAIVDTGTSLLVMPQGAYNRIIKDLGVSSDGEISCDDISKLPDVTFHINGHAFTLPASAYVLNEDGSCMLGFENMGTPTELGEQWILGDVFIREYYVIFDRANNKVGLSPLS", "length": 382, "header": "tr|Q9PRG9-1|Q9PRG9_CHICK Isoform 1 of pepsin A OS=Gallus gallus OX=9031 GN=PGA5 PE=3 SV=1 CANONICAL=Q9PRG9-1" }, "locus": { "chromosome": "5", "start_pos": 262826, "end_pos": 260678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047546.1", "url": "https://www.ensembl.org/id/ENSGALT00010047546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028152.1", "url": "https://www.ensembl.org/id/ENSGALP00010028152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395691", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9PRG9", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "Q9PRG9", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "Q9PRG9", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9PRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRG9" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 379, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.23.1", "ec_name": "Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves 1-Phe-|-Val-2, 4-Gln-|-His-5, 13-Glu-|-Ala-14, 14-Ala-|-Leu-15, 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17, 23-Gly-|-Phe-24, 24-Phe-|-Phe-25 and 25-Phe-|-Tyr-26 bonds in the B chain of insulin.", "evidence": [ { "id": "3.4.23.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.23.1" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q9PRL8-1", "uniprot_ac": "Q9PRL8", "uniprot_id": "ACBP_CHICK", "mass": { "chemical_mass": 9645.0, "monoisotopic_mass": 9645.0 }, "refseq": {}, "gene_names": [ { "name": "DBI", "type": "recommended", "evidence": [ { "id": "Q9PRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8" } ] } ], "protein_names": [ { "name": "Acyl-CoA-binding protein", "type": "recommended", "evidence": [ { "id": "Q9PRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8/entry#names_and_taxonomy" } ] }, { "name": "ACBP", "type": "synonym", "evidence": [ { "id": "Q9PRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8/entry#names_and_taxonomy" } ] }, { "name": "DBI", "type": "synonym", "evidence": [ { "id": "Q9PRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8/entry#names_and_taxonomy" } ] }, { "name": "Diazepam-binding inhibitor", "type": "synonym", "evidence": [ { "id": "Q9PRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.", "evidence": [ { "database": "UniProtKB", "id": "Q9PRL8", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9PRL8", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DBI", "url": "https://www.uniprot.org/uniprotkb/Q9PRL8", "locus": { "chromosome": "7", "start_pos": 27997218, "end_pos": 28013934, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020747", "url": "https://www.ensembl.org/id/ENSGALG00010020747" } ] } } ], "crossref": [ { "id": "Q9PRL8", "url": "https://alphafold.ebi.ac.uk/entry/Q9PRL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00435", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00435", "database": "CDD", "categories": [ 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"annotation": "##Evidence-Data-START## Transcript exon combination :: AF420601.1, SRR13267662.11140.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000374.1. On Aug 23, 2011 this sequence version replaced NP_989435.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989435" } ] }, { "annotation": "Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RX1", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0", "locus": {} } ], "crossref": [ { "id": "Q9PVY0", "url": "https://alphafold.ebi.ac.uk/entry/Q9PVY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013431", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013431", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "373893", "url": "https://www.ncbi.nlm.nih.gov/gene/373893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:373893", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAPTPYQ", "url": "https://omabrowser.org/oma/group/MAPTPYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9PVY0", "url": "https://www.orthodb.org/?gene=Q9PVY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46271:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46271:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9PVY0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9PVY0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9PVY0-1", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLNKCEGDLGELRKPGDSEGTPPAAAEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKMEASSMKLHDTPMLSFNRPPMTANVGPMSNSLPLDPWLTSPISSATPVHSIPGFMGAPQALQPPYGGHSFLNTPPGMAQGMQPMAPAPYQCGTPFVDKYPLEDVDQRSSSIASLRMKAKEHIQTIDKTWQPI", "length": 228, "header": "sp|Q9PVY0-1|RX1_CHICK Isoform 1 of Retinal homeobox protein Rx1 OS=Gallus gallus OX=9031 GN=RX1 PE=2 SV=1 CANONICAL=Q9PVY0-1" }, "isoforms": [ { "isoform_ac": "Q9PVY0-1", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0/entry#Q9PVY0-1", "sequence": { "sequence": "MFLNKCEGDLGELRKPGDSEGTPPAAAEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKMEASSMKLHDTPMLSFNRPPMTANVGPMSNSLPLDPWLTSPISSATPVHSIPGFMGAPQALQPPYGGHSFLNTPPGMAQGMQPMAPAPYQCGTPFVDKYPLEDVDQRSSSIASLRMKAKEHIQTIDKTWQPI", "length": 228, "header": "sp|Q9PVY0-1|RX1_CHICK Isoform 1 of Retinal homeobox protein Rx1 OS=Gallus gallus OX=9031 GN=RX1 PE=2 SV=1 CANONICAL=Q9PVY0-1" }, "locus": { "chromosome": "28", "start_pos": 1391001, "end_pos": 1388890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068071.1", "url": "https://www.ensembl.org/id/ENSGALT00010068071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041814.1", "url": "https://www.ensembl.org/id/ENSGALP00010041814.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of chick rax/rx genes with overlapping patterns of expression during early eye and brain development.", "journal": "Mech. Dev.", "date": "1999", "authors": "Ohuchi H, Tomonari S, Itoh H, Mikawa T, Noji S", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "reference": [ { "type": "PubMed", "id": "10415362", "url": "https://glygen.org/publication/PubMed/10415362" } ] }, { "title": "The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation.", "journal": "Development", "date": "2002", "authors": "Chen C-M Amy, Cepko Constance L", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "reference": [ { "type": "PubMed", "id": "12403708", "url": "https://glygen.org/publication/PubMed/12403708" } ] } ], "pathway": [ { "id": "gga:373893", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373893", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9PVY0", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9PVY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9PVY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9PVY0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9PVY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000255", "start_pos": 36, "end_pos": 95, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9PVY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear localization signal", "eco_id": "ECO_0000255", "start_pos": 211, "end_pos": 215, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9PVY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PVY0" }, { "id": "PRU00138", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00138" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "OAR", "eco_id": "ECO_0000255", "start_pos": 205, "end_pos": 218, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q9PWA3-1", "uniprot_ac": "Q9PWA3", "uniprot_id": "GRIN2_CHICK", "mass": { "chemical_mass": 56859.0, "monoisotopic_mass": 56859.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "GRIN2-like protein", "type": "recommended", "evidence": [ { "id": "Q9PWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3/entry#names_and_taxonomy" } ] }, { "name": "G protein-regulated inducer of neurite outgrowth 2-like protein", "type": "synonym", "evidence": [ { "id": "Q9PWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3/entry#names_and_taxonomy" } ] }, { "name": "G(o)-alpha-interacting protein 6", "type": "synonym", "evidence": [ { "id": "Q9PWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in neurite outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "Q9PWA3", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9PWA3", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3", "locus": {} } ], "crossref": [ { "id": "Q9PWA3", "url": "https://alphafold.ebi.ac.uk/entry/Q9PWA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9PWA3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9PWA3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "Q9PWA3", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9PWA3-1", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLESVVQTMNNQSPDNNSQSRTKTTNHFLIIEQSPASWEVGDTKMCVKSSTVENVSSACFKHQQSMGKMDEPRAVLQRSHSDLTCSCKQQSYVTHVETSATDSSLSSSSSRHGPSVVRMSFQTERYGSGIRNKENTSHYQNLVTHLPALPIDQKVPTNTFDSGGIPHNTTVYTDPGRFHSAVLGPHMPGNGFSNRTMLSQATGIIHGGLTYSNIPNSAFSPMAMTVHNSSAVPCNIRQDSCMKVDATIPAYCHSLPIPSIQLVPRLVCSVSESGKEQAAPDYFHSFSTSDILTYPKLVSSVSESGLDAKRVLKCCSIPGEQLQHAQRCTQQERASSETQTACVAFSSQQTTDVAMKTKDMWTMTSANDLTKGLKPALERRDAEVQTLPTMECKSVATSPAAAAESHSHVFPEVNLEQDLEAPKSPVREVRWDDEGMTWEVYGASVDPEVLGLAIQKHLEIQIEQFQTEPAQQTGKSDEDPLNKEPSSDKMEKKRPFRTMMHSLRYPSCCARSSTAVE", "length": 518, "header": "sp|Q9PWA3-1|GRIN2_CHICK Isoform 1 of GRIN2-like protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=Q9PWA3-1" }, "isoforms": [ { "isoform_ac": "Q9PWA3-1", "url": "https://www.uniprot.org/uniprotkb/Q9PWA3/entry#Q9PWA3-1", "sequence": { "sequence": "MGLESVVQTMNNQSPDNNSQSRTKTTNHFLIIEQSPASWEVGDTKMCVKSSTVENVSSACFKHQQSMGKMDEPRAVLQRSHSDLTCSCKQQSYVTHVETSATDSSLSSSSSRHGPSVVRMSFQTERYGSGIRNKENTSHYQNLVTHLPALPIDQKVPTNTFDSGGIPHNTTVYTDPGRFHSAVLGPHMPGNGFSNRTMLSQATGIIHGGLTYSNIPNSAFSPMAMTVHNSSAVPCNIRQDSCMKVDATIPAYCHSLPIPSIQLVPRLVCSVSESGKEQAAPDYFHSFSTSDILTYPKLVSSVSESGLDAKRVLKCCSIPGEQLQHAQRCTQQERASSETQTACVAFSSQQTTDVAMKTKDMWTMTSANDLTKGLKPALERRDAEVQTLPTMECKSVATSPAAAAESHSHVFPEVNLEQDLEAPKSPVREVRWDDEGMTWEVYGASVDPEVLGLAIQKHLEIQIEQFQTEPAQQTGKSDEDPLNKEPSSDKMEKKRPFRTMMHSLRYPSCCARSSTAVE", "length": 518, "header": "sp|Q9PWA3-1|GRIN2_CHICK Isoform 1 of GRIN2-like protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=Q9PWA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.", "journal": "J. Biol. 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"MYPRNSSQAQPFLLAGLPGMAQFHHWVFLPFGLMYLVAVLGNGTILLVVRVHRQLHQPMYYFLLMLATTDLGLTLSTLPTVLRVFWLGAMEISFPACLIQMFCIHVFSFMESSVLLAMAFDRYVAICCPLRYSSILTGARVAQIGLGIICRCTLSLLPLICLLTWLPFCRSHVLSHPYCLHQDIIRLACTDATLNSLYGLILVLVAILDFVLIALSYIMIFRTVLGITSKEEQTKALNTCVSHFCAVLIFYIPLAGLSIIHRYGRNAPPISHAVMANVYLFVPPILNPVLYSMKSKAICKGLLRLLCQRAAWPGHAQNC", "length": 319, "header": "tr|Q9YH55-1|Q9YH55_CHICK Isoform 1 of Olfactory receptor OS=Gallus gallus OX=9031 GN=OR51M1 PE=3 SV=1 CANONICAL=Q9YH55-1" }, "locus": { "chromosome": "1", "start_pos": 195992875, "end_pos": 195991919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007829.1", "url": "https://www.ensembl.org/id/ENSGALT00010007829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004697.1", "url": "https://www.ensembl.org/id/ENSGALP00010004697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428116", "name": "", "url": 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"eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q9YH98-1", "uniprot_ac": "Q9YH98", "uniprot_id": "EYA4_CHICK", "mass": { "chemical_mass": 13340.0, "monoisotopic_mass": 13340.0 }, "refseq": { "ac": "NP_001292106", "name": "protein phosphatase EYA4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106" }, "gene_names": [ { "name": "EYA4", "type": "recommended", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ] }, { "name": "EYA4", "type": "synonym", "evidence": [ { "id": "NP_001292106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106" } ] } ], "protein_names": [ { "name": "Protein phosphatase EYA4", "type": "recommended", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98/entry#names_and_taxonomy" } ] }, { "name": "Eyes absent homolog 4", "type": "synonym", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98/entry#names_and_taxonomy" } ] }, { "name": "eyes absent homolog 4", "type": "synonym", "evidence": [ { "id": "NP_001292106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106" } ] }, { "name": "protein phosphatase EYA4", "type": "synonym", "evidence": [ { "id": "NP_001292106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001292106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106" } ] }, { "annotation": "Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98#function" }, { "database": "UniProtKB", "id": "Q99502", "url": "https://www.uniprot.org/uniprotkb/Q99502#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EYA4", "url": "https://www.uniprot.org/uniprotkb/Q9YH98", "locus": { "chromosome": "3", "start_pos": 56074460, "end_pos": 56228390, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006239", "url": "https://www.ensembl.org/id/ENSGALG00010006239" } ] } } ], "crossref": [ { "id": "Q9YH98", "url": "https://alphafold.ebi.ac.uk/entry/Q9YH98", "database": "AlphaFoldDB", "categories": [] }, { "id": "395716", "url": "https://www.ncbi.nlm.nih.gov/gene/395716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395716", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9YH98", "url": "https://www.orthodb.org/?gene=Q9YH98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10190:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10190:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001292106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9YH98-1", "url": "https://www.uniprot.org/uniprotkb/Q9YH98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RKLAFRYRRVKELYNTYKNNIGGLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNIT", "length": 119, "header": "sp|Q9YH98-1|EYA4_CHICK Isoform 1 of Protein phosphatase EYA4 OS=Gallus gallus OX=9031 GN=EYA4 PE=2 SV=1 CANONICAL=Q9YH98-1" }, "isoforms": [ { "isoform_ac": "Q9YH98-1", "url": "https://www.uniprot.org/uniprotkb/Q9YH98/entry#Q9YH98-1", "sequence": { "sequence": "RKLAFRYRRVKELYNTYKNNIGGLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNIT", "length": 119, "header": "sp|Q9YH98-1|EYA4_CHICK Isoform 1 of Protein phosphatase EYA4 OS=Gallus gallus OX=9031 GN=EYA4 PE=2 SV=1 CANONICAL=Q9YH98-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "EYA4, a novel vertebrate gene related to Drosophila eyes absent.", "journal": "Hum. Mol. Genet.", "date": "1999", "authors": "Borsani G, DeGrandi A, Ballabio A, Bulfone A, Bernard L, Banfi S, Gattuso C, Mariani M, Dixon M, Donnai D, Metcalfe K, Winter R, Robertson M, Axton R, Brown A, van Heyningen V, Hanson I", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "reference": [ { "type": "PubMed", "id": "9887327", "url": "https://glygen.org/publication/PubMed/9887327" } ] } ], "pathway": [ { "id": "gga:395716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395716", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q9YH98", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", 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"https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": 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{ "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "O13016", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "Q5F4B1", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q5F4B1", 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GFA9-1", "uniprot_ac": "R4GFA9", "uniprot_id": "R4GFA9_CHICK", "mass": { "chemical_mass": 23699.0, "monoisotopic_mass": 23699.0 }, "refseq": { "ac": "XP_003643008", "name": "mediator of RNA polymerase II transcription subunit 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643008" }, "gene_names": [ { "name": "MED18", "type": "recommended", "evidence": [ { "id": "R4GFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ] }, { "name": "MED18", "type": "synonym", "evidence": [ { "id": "XP_003643008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643008" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 18", "type": "recommended", "evidence": [ { "id": "R4GFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFA9/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643008" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9#function" }, { "database": "UniProtKB", "id": "RU364150", "url": "https://www.uniprot.org/uniprotkb/RU364150#function" }, { "database": "UniProtKB", "id": "ARBA00025687", "url": "https://www.uniprot.org/uniprotkb/ARBA00025687#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MED18", "url": "https://www.uniprot.org/uniprotkb/R4GFA9", "locus": { "chromosome": "Z", "start_pos": 24524323, "end_pos": 24528297, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010990", "url": "https://www.ensembl.org/id/ENSGALG00010010990" } ] } } ], "crossref": [ { "id": "R4GFA9", "url": "https://alphafold.ebi.ac.uk/entry/R4GFA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028149", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028149", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857707", "url": "https://www.ncbi.nlm.nih.gov/gene/100857707", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857707", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857707", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARGYMFR", "url": "https://omabrowser.org/oma/group/ARGYMFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GFA9", "url": "https://www.orthodb.org/?gene=R4GFA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13321:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13321:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643008", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFA9-1", "url": "https://www.uniprot.org/uniprotkb/R4GFA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDQSLESLLHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDKSGMPWHLRYLGQPEIGDKNRHALVRNCVDIATSDNLTDFLVEMGFRMDHEFVAKGHVFRKGIMKIVVYKIFRILMPGNTDSIEPLSLSYLVELNVVAPAGQDIVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 208, "header": "tr|R4GFA9-1|R4GFA9_CHICK Isoform 1 of Mediator of RNA polymerase II transcription subunit 18 OS=Gallus gallus OX=9031 GN=MED18 PE=3 SV=1 CANONICAL=R4GFA9-1" }, "isoforms": [ { "isoform_ac": "R4GFA9-1", "url": "https://www.uniprot.org/uniprotkb/R4GFA9/entry#R4GFA9-1", "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDQSLESLLHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDKSGMPWHLRYLGQPEIGDKNRHALVRNCVDIATSDNLTDFLVEMGFRMDHEFVAKGHVFRKGIMKIVVYKIFRILMPGNTDSIEPLSLSYLVELNVVAPAGQDIVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 208, "header": "tr|R4GFA9-1|R4GFA9_CHICK Isoform 1 of Mediator of RNA polymerase II transcription subunit 18 OS=Gallus gallus OX=9031 GN=MED18 PE=3 SV=1 CANONICAL=R4GFA9-1" }, "locus": { "chromosome": "Z", "start_pos": 24528281, "end_pos": 24527456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026327.1", "url": "https://www.ensembl.org/id/ENSGALT00010026327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014951.1", "url": "https://www.ensembl.org/id/ENSGALP00010014951.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857707", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACJ8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "Med18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRNEMEAWTHCAFASSGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIVVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 201 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H1Z1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "Med18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIVVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 208 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VCD4-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "MED18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFVDHEMVFLLKGQQASPFVLRARRSLDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVARGHLFRKGIMKIVVYKIFRILVPGNTDNTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 208 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7T3H7-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "med18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAPPVTVMPVTGGTINMMEYLLQGSVLDQSLESLLHRLRGLCDNMEPESFADHELVYLLKGQQGNPFILRARRSLLDPSVPWHLRYLGQPEVGDKSRHALVRNCVDVAASHSLPDFLNEMGFRMDHEFVAKGQVFRKGVMKVVVSKLSRVLVPGNTDNTEPLSLSYLVELSVLAPAGQDTVSEDMRSFAEQLKPLVHLEKIDPKRLM", "length": 208 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BUE0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "MED18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIMVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMKNFAEQLKPLVHLEKIDPKRLM", "length": 208 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZ82-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "Med18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKVVVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM", "length": 208 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XZT1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "MED18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAIVSSARESLSHAMNNRFLPNLEYLLQGSILDSAVEHLMHRLKGLCDNVDTSPEPFHDLEVCMSLRQPNANQPLLLRVRRALGRDAPFQMRYLGNPEVDLRRPTLVRSCMDCACTNGILEFLTEMGFRLEFEYIAKGYMFRKGRMKITVSKLIKIVPGKQQDMANEPISQSYIVELSVVAPTGQENVGEEMRVFAEQLKPLVQLEKIDYKRLGGMP", "length": 217 }, "evidence": [ { "id": "R4GFA9", "url": "https://omabrowser.org/oma/group/R4GFA9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "R4GFA9", "url": "https://www.uniprot.org/uniprotkb/R4GFA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GFA9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 208, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GFA9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GFA9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GFI6-1", "uniprot_ac": "R4GFI6", "uniprot_id": "R4GFI6_CHICK", "mass": { "chemical_mass": 48977.0, "monoisotopic_mass": 48977.0 }, "refseq": { "ac": "XP_004949570", "name": "thymic stromal cotransporter homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949570" }, "gene_names": [ { "name": "LOC121106434", "type": "recommended", "evidence": [ { "id": "R4GFI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ] }, { "name": "LOC121106434", "type": "synonym", "evidence": [ { "id": "XP_004949570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949570" } ] }, { "name": "SLC46A2", "type": "synonym", "evidence": [ { "id": "R4GFI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ] } ], "protein_names": [ { "name": "Thymic stromal cotransporter homolog", "type": "recommended", "evidence": [ { "id": "R4GFI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GFI6/entry#names_and_taxonomy" } ] }, { "name": "thymic stromal cotransporter homolog", "type": "synonym", "evidence": [ { "id": "XP_004949570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949570" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GFI6", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106434", "url": "https://www.uniprot.org/uniprotkb/R4GFI6", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000027345", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "121106434", "url": "https://www.ncbi.nlm.nih.gov/gene/121106434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431636", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431636", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYWSGVM", "url": "https://omabrowser.org/oma/group/AYWSGVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GFI6", "url": "https://www.orthodb.org/?gene=R4GFI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23507", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23507", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23507:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23507:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GFI6", "url": "https://www.uniprot.org/uniprotkb/R4GFI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GFI6-1", "url": "https://www.uniprot.org/uniprotkb/R4GFI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGMMAMRTWVEPVVAGSQVASAFYDTALLLVVKNFYNQTNSTAPSHVMEDAQQKAVSNFYVIYNLVLGLSPLVSAYGLSKLGDKVHRKIPICVSLLGYLGSKSLLLLLILLDWPIEVMYGAAAFNGLTGGFTTFWAGIMALGSLGSSESRRSLRLIIVEMVYGLAGFLGSMASGYLFVGFSYHYREGTVLVSCSIACYAFCLLYSAFVLTVPKSAASCPDKAKSVEDSGSQLPAQTGGAESAQPSESSNRTPVTPSRLIIVMLFVAAILYDLAVVGAMNVLPLFLIREPLSWNAVEIGHGNAAGYVIFITSFLGVFVFSKYFKDITMIMIGVVSFSAGILIMAFVRWTFLFYIARAVMLFALIPLPTIRSMLSKHVEGSSYGKVFVLLQLSLVTTGVVTSTAYNKIYQSTLNWHSGFCFVLSFLAGCLSLLPLSVVAIKQRSSTGSFQLSTK", "length": 453, "header": "tr|R4GFI6-1|R4GFI6_CHICK Isoform 1 of Thymic stromal cotransporter homolog OS=Gallus gallus OX=9031 GN=LOC121106434 PE=3 SV=2 CANONICAL=R4GFI6-1" }, "isoforms": [ { "isoform_ac": "R4GFI6-1", "url": "https://www.uniprot.org/uniprotkb/R4GFI6/entry#R4GFI6-1", "sequence": { "sequence": "MVGMMAMRTWVEPVVAGSQVASAFYDTALLLVVKNFYNQTNSTAPSHVMEDAQQKAVSNFYVIYNLVLGLSPLVSAYGLSKLGDKVHRKIPICVSLLGYLGSKSLLLLLILLDWPIEVMYGAAAFNGLTGGFTTFWAGIMALGSLGSSESRRSLRLIIVEMVYGLAGFLGSMASGYLFVGFSYHYREGTVLVSCSIACYAFCLLYSAFVLTVPKSAASCPDKAKSVEDSGSQLPAQTGGAESAQPSESSNRTPVTPSRLIIVMLFVAAILYDLAVVGAMNVLPLFLIREPLSWNAVEIGHGNAAGYVIFITSFLGVFVFSKYFKDITMIMIGVVSFSAGILIMAFVRWTFLFYIARAVMLFALIPLPTIRSMLSKHVEGSSYGKVFVLLQLSLVTTGVVTSTAYNKIYQSTLNWHSGFCFVLSFLAGCLSLLPLSVVAIKQRSSTGSFQLSTK", "length": 453, "header": "tr|R4GFI6-1|R4GFI6_CHICK Isoform 1 of Thymic stromal cotransporter homolog OS=Gallus gallus OX=9031 GN=LOC121106434 PE=3 SV=2 CANONICAL=R4GFI6-1" }, "locus": { "chromosome": "Z", "start_pos": 66538410, "end_pos": 66533361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016529.1", "url": "https://www.ensembl.org/id/ENSGALT00010016529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009377.1", "url": "https://www.ensembl.org/id/ENSGALP00010009377.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 255, "start_aa": "Thr", "end_pos": 255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:431636", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431636", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A6S9-1", "protein_name": "Solute carrier family 46, member 2", "gene_name": "Slc46a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPGFTCPWSGSLSGFRVRTWIEPVVASTQVAGSLYDTGLLLVLKESFASDARDSSNYSANQSLGERQEDQQQKAISNFYIIYNLVVGLTPLLSAYVLGWLSDRYHRKISICTAMLGFLLSRIGLLLKVMLDWPLEVMYGAAALNGLCGGFSAYWSGVMALGSLSCSQSRRSVRLILIDLVLGLAGFCGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPEAVSKPNKVHPTVDTVSGMMGTYRTLDPDQQDKPNIQANPPTPGKEKPSQAIIALLFVGAIVYDLAVVGTLDVMALFVLKDPLHWNQVQLGYGMASGYIIFITSFLGVLVFSRYFRDTTMIIIGMVSFGSGALLLAFVKKTYMFYIARAVMLFALIPITTIRSAMSKLVKDSSYGKIFVILQLCLALTGVVTSTMYNKIYQLTLNKFAGTCFLLSSFLSFLAIVPIGVVAYKQVPGSRQGECADTQRS", "length": 480 }, "evidence": [ { "id": "R4GFI6", "url": "https://omabrowser.org/oma/group/R4GFI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SNA4-1", "protein_name": "Solute carrier family 46 member 2", "gene_name": "SLC46A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPGAICPWRGPLPRLQVWTWIEPVVASNQVATSLYDAGLLLVVKASFGVGAFSNHSASPSPRGALEDQQQRALSNFYIIYNLVMGLTPLLSAYWLGWLSDRYHRKIAICVPLLGFLLSRLALLLKVLLDWPVEMLYGAAALNGLCGGFSAFWSGVMALGSLGSSEGRRSLRLILIDLILGLAGFCGSMVSGHLFKQMVGHTRQGLVLTACSVSCASCALFYSLLVLKVPESMAKPSKTADTVSGTVGTYRTLDPDQPASQSVVGHPPAPGKARPQKTIIALLFVGAVIYDLAVVGTVDVIPLFVLREPLSWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAAMLFALIPITTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTVYNEIYQLTMEKFVGTCFALSSFLSFLAIIPIGIVATKQASLLQYGDTAEK", "length": 472 }, "evidence": [ { "id": "R4GFI6", "url": "https://omabrowser.org/oma/group/R4GFI6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CA03-1", "protein_name": "Solute carrier family 46 member 2", "gene_name": "Slc46a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPGGTCPWSSRLSGFRVRTWIEPVVASTQVAGSLYDAGLLLVVKESFKSEAGGSSNYSANQSLVEYQEDQQQKAISNFNIIYNLVLGLTPLLSAYGLGWLSDRYHRKISICTAMLGFLLSRIGLLLKVMLDWPVEVMYGAAALNGLCGSFSAYWSGVMALGSLGCSEGRRSVRLILIDLVLGLAGFSGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPESKPNKVHPTVDTVSGMMGTYRTLDPDQQDKQNVPRNPRTPGKGKSSQREVVALLFVGAIIYDLAAVGTVDVMALFVLKEPLHWNQVQLGYGMASGYIIFITSFLGVLVFSRCFRDTTMIIIGMLSFGSGALLLAFVKETYMFYIARAIMLFALIPITTIRSAMSKLIKDSSYGKIFVILQLCLTLTGVVTSTIYNKIYQLTLDKFIGTCFVLSSFLSFLAIVPIGVVAYKQVPRSQQGECAEKQRS", "length": 479 }, "evidence": [ { "id": "R4GFI6", "url": "https://omabrowser.org/oma/group/R4GFI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY10-1", "protein_name": "Solute carrier family 46 member 2", "gene_name": "SLC46A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPEVTCPRRGHLPRFHPRTWVEPVVASSQVAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK", "length": 475 }, "evidence": [ { "id": "R4GFI6", "url": "https://omabrowser.org/oma/group/R4GFI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GFI6", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "R4GFI6", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "R4GFI6", "url": "https://www.uniprot.org/uniprotkb/R4GFI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 255 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 38, "end_pos": 40 }, { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GG67-1", "uniprot_ac": "R4GG67", "uniprot_id": "R4GG67_CHICK", "mass": { "chemical_mass": 6767.0, "monoisotopic_mass": 6767.0 }, "refseq": { "ac": "NP_001157812", "name": "single-pass membrane and coiled-coil domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" }, "gene_names": [ { "name": "SMCO4", "type": "recommended", "evidence": [ { "id": "R4GG67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG67" } ] }, { "name": "C11ORF75", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] }, { "name": "C1H11orf75", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] }, { "name": "FN5", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] }, { "name": "SMCO4", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] } ], "protein_names": [ { "name": "Single-pass membrane and coiled-coil domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "R4GG67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GG67/entry#names_and_taxonomy" } ] }, { "name": "UPF0443 protein C11orf75", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] }, { "name": "single-pass membrane and coiled-coil domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001157812", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01011854.1, HAEL01003888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Aug 22, 2009 this sequence version replaced XP_001235372.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001157812", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GG67", "url": "https://www.uniprot.org/uniprotkb/R4GG67" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMCO4", "url": "https://www.uniprot.org/uniprotkb/R4GG67", "locus": { "chromosome": "1", "start_pos": 185794046, "end_pos": 185764676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008974", "url": "https://www.ensembl.org/id/ENSGALG00010008974" } ] } } ], "crossref": [ { "id": "ENSGALG00000026639", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026639", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "772206", "url": "https://www.ncbi.nlm.nih.gov/gene/772206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772206", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772206", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFIYANT", "url": "https://omabrowser.org/oma/group/FFIYANT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR34644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34644:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34644:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001157812", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GG67", "url": "https://www.uniprot.org/uniprotkb/R4GG67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GG67-1", "url": "https://www.uniprot.org/uniprotkb/R4GG67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQLRGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPNTTE", "length": 59, "header": "tr|R4GG67-1|R4GG67_CHICK Isoform 1 of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Gallus gallus OX=9031 GN=SMCO4 PE=3 SV=1 CANONICAL=R4GG67-1" }, "isoforms": [ { "isoform_ac": "R4GG67-1", "url": "https://www.uniprot.org/uniprotkb/R4GG67/entry#R4GG67-1", "sequence": { "sequence": "MRQLRGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPNTTE", "length": 59, "header": "tr|R4GG67-1|R4GG67_CHICK Isoform 1 of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Gallus gallus OX=9031 GN=SMCO4 PE=3 SV=1 CANONICAL=R4GG67-1" }, "locus": { "chromosome": "1", "start_pos": 185792970, "end_pos": 185792794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021348.1", "url": "https://www.ensembl.org/id/ENSGALT00010021348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012173.1", "url": "https://www.ensembl.org/id/ENSGALP00010012173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772206", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FNY6-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVVLIVVFVYVATRPTITE", "length": 59 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FVK8-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "Smco4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIAEESQEQTQRCAGSASRRCSNLDCLSGLGQLTVRSSPGSWRRITQITLTGSRLTDITEFEVKRPPAWTEDCGPSSKTSLGTSSHHHLAKMRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 150 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q32PD9-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRQLKGKPKKETSRDKKERKQAMQEARRQITTVVLPTLAVVVLLIVVFVYVATRPASTE", "length": 59 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8SY72-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRQLKGKVKETRKQKKERKLDNLETQAKIRTVVLPALGVLAVFLVLFVYLKTRPAVLA", "length": 58 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9JIS3-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "Smco4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPAVTE", "length": 59 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRQ5-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTITE", "length": 59 }, "evidence": [ { "id": "R4GG67", "url": "https://omabrowser.org/oma/group/R4GG67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GG67", "url": "https://www.uniprot.org/uniprotkb/R4GG67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGA2-1", "uniprot_ac": "R4GGA2", "uniprot_id": "R4GGA2_CHICK", "mass": { "chemical_mass": 73690.0, "monoisotopic_mass": 73690.0 }, "refseq": { "ac": "XP_003643093", "name": "solute carrier organic anion transporter family member 4C1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643093" }, "gene_names": [ { "name": "SLCO4C1", "type": "recommended", "evidence": [ { "id": "R4GGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ] }, { "name": "SLCO4C1", "type": "synonym", "evidence": [ { "id": "XP_003643093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643093" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "R4GGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGA2/entry#names_and_taxonomy" } ] }, { "name": "solute carrier organic anion transporter family member 4C1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643093" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643093" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLCO4C1", "url": "https://www.uniprot.org/uniprotkb/R4GGA2", "locus": { "chromosome": "Z", "start_pos": 50954486, "end_pos": 50928151, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012226", "url": "https://www.ensembl.org/id/ENSGALG00010012226" } ] } } ], "crossref": [ { "id": "R4GGA2", "url": "https://alphafold.ebi.ac.uk/entry/R4GGA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026768", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026768", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769132", "url": "https://www.ncbi.nlm.nih.gov/gene/769132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769132", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCENEPF", "url": "https://omabrowser.org/oma/group/KCENEPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GGA2", "url": "https://www.orthodb.org/?gene=R4GGA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-879518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGA2-1", "url": "https://www.uniprot.org/uniprotkb/R4GGA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGNDGIENPAFEPPTPVFGGRRRASPAGAGVAAEAPPVEEAEEGPCGWGRCTPKVLQLCNTPEGYLAAYSLLAIFQGIVVNGLINISISTIEKRYELNSSLTGLISASYDIAFCVLSLFVSFFGERGHKPRWLAFSAFMLGLGSLVFSLPHFSSGKYHYGAKLEDTCQISGASSANFTCSASTKSSLSNYLYVFILGQLLLGVGGTPLYTLGTAFIDDSVPKHTSSLYIGIGYAMSLLGPAIGYVLGGQLLSIYIDIKIPESTQMDQDDPRWLGAWWIGFLACFFAMWFLIIPFSCFPKYLPGTAKIQAEKISETHNDGSEALVEAKNIGKNFRDFPIALLILLKNPVLMSLILASTSEALVATGFATFLPKFIENQFGMTSSFSATLGGLVLVPAAALGQVISGILVSKYKMDCKNMIKFMIGTCSVAFLLNTVFLVAKCGNEPFAGVSETYNGTGMLHNLTAPCNANCRCSSSRYYPVCGRDEVQYFSPCFAGCASYNLNNKKKTYYNCSCIGKLKRENISEDFLSEAVPGKCPTRCKHLPLFLIYFFFAVVFTFMAVTPTTVAVLRCVPDKQRSFALGVQSVFLRLLGTVPGPILFGFAIDNSCSLWDVNECRTKGACWVYDNERMAYLLMSISAACKIITIIFVVVAVFLYKPPQPRPALPQKDSEMVSAIHA", "length": 678, "header": "tr|R4GGA2-1|R4GGA2_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO4C1 PE=3 SV=3 CANONICAL=R4GGA2-1" }, "isoforms": [ { "isoform_ac": "R4GGA2-1", "url": "https://www.uniprot.org/uniprotkb/R4GGA2/entry#R4GGA2-1", "sequence": { "sequence": "MKGNDGIENPAFEPPTPVFGGRRRASPAGAGVAAEAPPVEEAEEGPCGWGRCTPKVLQLCNTPEGYLAAYSLLAIFQGIVVNGLINISISTIEKRYELNSSLTGLISASYDIAFCVLSLFVSFFGERGHKPRWLAFSAFMLGLGSLVFSLPHFSSGKYHYGAKLEDTCQISGASSANFTCSASTKSSLSNYLYVFILGQLLLGVGGTPLYTLGTAFIDDSVPKHTSSLYIGIGYAMSLLGPAIGYVLGGQLLSIYIDIKIPESTQMDQDDPRWLGAWWIGFLACFFAMWFLIIPFSCFPKYLPGTAKIQAEKISETHNDGSEALVEAKNIGKNFRDFPIALLILLKNPVLMSLILASTSEALVATGFATFLPKFIENQFGMTSSFSATLGGLVLVPAAALGQVISGILVSKYKMDCKNMIKFMIGTCSVAFLLNTVFLVAKCGNEPFAGVSETYNGTGMLHNLTAPCNANCRCSSSRYYPVCGRDEVQYFSPCFAGCASYNLNNKKKTYYNCSCIGKLKRENISEDFLSEAVPGKCPTRCKHLPLFLIYFFFAVVFTFMAVTPTTVAVLRCVPDKQRSFALGVQSVFLRLLGTVPGPILFGFAIDNSCSLWDVNECRTKGACWVYDNERMAYLLMSISAACKIITIIFVVVAVFLYKPPQPRPALPQKDSEMVSAIHA", "length": 678, "header": "tr|R4GGA2-1|R4GGA2_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO4C1 PE=3 SV=3 CANONICAL=R4GGA2-1" }, "locus": { "chromosome": "Z", "start_pos": 50953873, "end_pos": 50928210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029314.1", "url": "https://www.ensembl.org/id/ENSGALT00010029314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017021.1", "url": "https://www.ensembl.org/id/ENSGALP00010017021.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 562, "start_aa": "Thr", "end_pos": 562, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr562", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:769132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769132", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-879518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879518", "resource": "Reactome", "description": "Organic anion transport by SLCO transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JCU8-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "Slco4c1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQGPKGIENPAFVPSSPDTPRRASASPSQVEVSAVTSRNQNGDSQPRESEEPQKSSESPPPLSTPPASDEPPGSQLCELEEGPCGWRDFHPRCLQLCNTPQGFLFHYCLLALTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPHFFSGRYELGSLFEDTCLTTRNSTSCESTSSLLSNYLYIFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQLLRMYIDVAMGQSSDVTEDDPRWLGAWWIGFLLAWLFAWSLIIPFSCFPKYLPGTAKIQAGKTSQTHQNSSTSFQHTDENFGKSIKDFPTAIKNLMRNTVFICLVLSTTSEALVTTGFATFLPKFIENQFGVTPSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCKNTMKFALFTSGVALTLSFVFIYAKCENEPFAGVSESYNGTGELGNLTAPCNANCNCLRSYYYPLCGSDGIQYFSPCFAGCVNSVSSRKPKVYYNCSCIERKAEITSTVESADFEAKAGKCETHCANLPIFLGIFFITVIFTFMAGTPITVSILRCVNHSERSLALGVQFMLLRLIGTIPGPIIFGVTIDSTCVLWDVNECGIKGACWIYDNIRMAHMLVAISVTCKVITMFFNGLAIVLYKPPTTGTEASFQSQNVIVSTISIEEDFNKVENEG", "length": 725 }, "evidence": [ { "id": "R4GGA2", "url": "https://omabrowser.org/oma/group/R4GGA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T623-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "SLCO4C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKSCKGIENPAFVSSSPDTPRRVCASSPSIDISVLPTPAAGSPPPPAPQEPLEPPQLSGVPGASELESLSEYEEGPCGWGSFQPRALQRCNTPGGFLFHYCLLALTQGIVVNGLVNISISTIEKRYELQSSLTGLISSSYDIAFCLLSLFVSFIGERGHKPRWLAFASFMLGLGALVFSLPKFFSGKYQFGSLYEDTCLTAKNKGSCSTSSSPLFYYLYVFILGQLFLGTGGTPLYTLGTAFIDDSVPIHKSSLYIGIGYAMSILGPAVGYVLGGQLLTLYIDVDLKHSIDITEDDPRWLGAWWIGFLISWLLAWSLIIPFSCFPKHLPGTAKIQEGKVSQTHQSASLQATDGNFGQSFKDFPAALKNLMRNTVFMCLVLSTCSEALITTGFATFLPKFIENQFGLSSSSAATLAGTVLIPGAALGQILGGVLVSKFKMMCKNIMKFALLTSVISLVLTFVFAYANCENEPFAGVSESYNGTGELGNLTAPCNAHCNCLRSYYYPVCGGNGVQYFSPCYAGCTQSVSKIHPKVYYNCSCIEGEIHITPTPSSVSLEAQAGKCSSQCKNLPPFLGVFFAAIVFTFMAGTPITVSILRCVNQRQRSLALGIQCTLLRLLGTIPGPIIFGSTIDSTCILWDINECGNKGACWIYNNVRMAYMLVAISVICKIITVFFNGLAVFLYKPPPSVTDVAFQNQNAVLTAVSLECDLNKAGNDG", "length": 716 }, "evidence": [ { "id": "R4GGA2", "url": "https://omabrowser.org/oma/group/R4GGA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZQN7-1", "protein_name": "Solute carrier organic anion transporter family member 4C1", "gene_name": "SLCO4C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQDLNKIVKEG", "length": 724 }, "evidence": [ { "id": "R4GGA2", "url": "https://omabrowser.org/oma/group/R4GGA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71MB6-1", "protein_name": "Solute carrier organic anion transporter family member 4C1", "gene_name": "Slco4c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGSKGVENPAFVPSSPDTPRRASASPSQVEVSAVASRNQNGGSQPRESEDPQKSTEPSPPSSTLPASDEPPGSQLSELEEGPCGWRNFHPQCLQRCNNPKGFLLHYCLLALTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFASFMIGLGALVFSLPHFFSGRYELGTIFEDTCLTRNSTRCASSTSLLSNYFYVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQLLTMYIDVAMGQSSDLTEDDPRWLGAWWIGFLLAWLFAWSLIMPFSCFPKHLPGTAKIQAGKTSQTHQNNSTSFQHMDENFGKSIKDFPTAVKNLMRNTVFICLVLSTTSEALVTTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCKNTMKFALCTSGVALMLSFVFIYAKCENGPFAGVSESYNGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGVQYFSPCFAGCLNSVSNRKPKAYYNCSCIERKVDITSTAXSPDFEARAGKCKTQCSNLPIFLGIFFITVIFTFMAGTPITVSILRCVNHRQRSLALGVQFMLLRLLGTIPGPIIFGVTIDSTCVLWDINECGTKGACWIYDNIRMAHMLVAISVTCKVITIFFNGLAIVLYKPPPPGTEVSFQSQNVVVSTITVEEDLNKIENEG", "length": 724 }, "evidence": [ { "id": "R4GGA2", "url": "https://omabrowser.org/oma/group/R4GGA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGD4-1", "protein_name": "Solute carrier organic anion transporter family member 4C1", "gene_name": "Slco4c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGSKGIENPAFVPSSPGTPRRASASPSQVEVSAVASRNQNGGSQPRESEEPQKSTEPSPPSSNPPASDEPPGSQLSELEEGPCGWRGFHPQCLQRCNTPQGFLLHYCLLALTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFASFMIGLGALVFSLPHFFSGRYELGSIFEDTCLTRNSTRCSSSTSLLSNYFYVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQLLTMYIDIAMGQSSDLTEDDPRWLGAWWIGFLLAWLFAWSLIMPFSCFPKHLPGTAKIQAGKTSQTHQNNSTSFQHTDENFGKSIKDFPTAVKNLMRNTVFICLVLSTTSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCKNTMKFALCTSGVALVLSFVFIYAKCENEPFAGVSESYNGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGIQYFSPCFAGCLNSVSNRKPKVYYNCSCIERKITSTAESTDFEAKAGKCRTRCSNLPIFLGIFFITVIFTFMAGTPITVSILRCVNHRHRSLALGVQFMLLRLLGTIPGPIIFGVIIDSTCVLWDVNECGIKGACWIYDNIKMAHMLVAISVTCKVITIFFNGLAIVLYKPPPPGTEVSFQSQNVIVSTISVEEDLDKAENEG", "length": 722 }, "evidence": [ { "id": "R4GGA2", "url": "https://omabrowser.org/oma/group/R4GGA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "R4GGA2", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GGA2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 678, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GGA2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GGA2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 461, "end_pos": 516, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "R4GGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGA2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 657, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 207, 562 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGB2-1", "uniprot_ac": "R4GGB2", "uniprot_id": "R4GGB2_CHICK", "mass": { "chemical_mass": 24243.0, "monoisotopic_mass": 24243.0 }, "refseq": { "ac": "XP_423834", "name": "probable glutathione peroxidase 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423834" }, "gene_names": [ { "name": "GPX8", "type": "recommended", "evidence": [ { "id": "R4GGB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ] }, { "name": "GPX8", "type": "synonym", "evidence": [ { "id": "XP_423834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423834" } ] } ], "protein_names": [ { "name": "Glutathione peroxidase", "type": "recommended", "evidence": [ { "id": "R4GGB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGB2/entry#names_and_taxonomy" } ] }, { "name": "probable glutathione peroxidase 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_423834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423834" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423834" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPX8", "url": "https://www.uniprot.org/uniprotkb/R4GGB2", "locus": { "chromosome": "Z", "start_pos": 17240737, "end_pos": 17236443, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015118", "url": "https://www.ensembl.org/id/ENSGALG00010015118" } ] } } ], "crossref": [ { "id": "R4GGB2", "url": "https://alphafold.ebi.ac.uk/entry/R4GGB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026704", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026704", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426170", "url": "https://www.ncbi.nlm.nih.gov/gene/426170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTWNFCK", "url": "https://omabrowser.org/oma/group/PTWNFCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GGB2", "url": "https://www.orthodb.org/?gene=R4GGB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11592:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11592:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_423834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16833", "url": "https://www.rhea-db.org/rhea/16833", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGB2-1", "url": "https://www.uniprot.org/uniprotkb/R4GGB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPLTAAYPLKYSVPKARVFVVFLSMVFCTAVLCLLQLRFFKPKTKDFYSFEIKDSRGRIVSLEKYRGKATLVVNVASYCQHTDKNYIALQDLHREFGPSHFTVLAFPCNQFGESEPGSSQEIEAFAKGNYGVTFPVFHKIKILGSEAEPAFKFLIDSSKKEPRWNFWKYLVSPEGKVVKFWRPEEPIESIKPEIASLIRQIIMKKREDL", "length": 210, "header": "tr|R4GGB2-1|R4GGB2_CHICK Isoform 1 of Glutathione peroxidase OS=Gallus gallus OX=9031 GN=GPX8 PE=3 SV=1 CANONICAL=R4GGB2-1" }, "isoforms": [ { "isoform_ac": "R4GGB2-1", "url": "https://www.uniprot.org/uniprotkb/R4GGB2/entry#R4GGB2-1", "sequence": { "sequence": "MEPLTAAYPLKYSVPKARVFVVFLSMVFCTAVLCLLQLRFFKPKTKDFYSFEIKDSRGRIVSLEKYRGKATLVVNVASYCQHTDKNYIALQDLHREFGPSHFTVLAFPCNQFGESEPGSSQEIEAFAKGNYGVTFPVFHKIKILGSEAEPAFKFLIDSSKKEPRWNFWKYLVSPEGKVVKFWRPEEPIESIKPEIASLIRQIIMKKREDL", "length": 210, "header": "tr|R4GGB2-1|R4GGB2_CHICK Isoform 1 of Glutathione peroxidase OS=Gallus gallus OX=9031 GN=GPX8 PE=3 SV=1 CANONICAL=R4GGB2-1" }, "locus": { "chromosome": "Z", "start_pos": 17239022, "end_pos": 17236453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036404.1", "url": "https://www.ensembl.org/id/ENSGALT00010036404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021179.1", "url": "https://www.ensembl.org/id/ENSGALP00010021179.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JGT2-1", "protein_name": "Glutathione peroxidase", "gene_name": "Gpx8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPFAAYPLKCSGSKAKVFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGKIVSLEKFKGKEASLVVNVASDCRYTDKSYLTLKELHKEFGPYHFNVLAFPCNQFGESEPRSSTEVESFARRNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPMWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMVGQMILKKKEDL", "length": 210 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZPW7-1", "protein_name": "Glutathione peroxidase", "gene_name": "Gpx8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPLGAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGRMVSLEKFKGKASLVVNVASDCRFTDKSYETLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARKNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "length": 209 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36014-1", "protein_name": "Glutathione peroxidase-like peroxiredoxin 1", "gene_name": "GPX1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI", "length": 167 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2NL01-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "GPX8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPLTAYPLRCSGPKAKAFAVLLSMVLCTVMLFLLQLKFLKPKINSFYTFEVKDANGRVVSLEKFKGKVALVVNVASDCQLTDRNYLALQELHKEFGPFHFSVLAFPCNQFGESEPRPSKEVVSFARNNFGVTFPIFHKIKILGSEAEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKTWRPEEPIEVIRPEIAALIRQMIIKKKEDL", "length": 209 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8L910-1", "protein_name": "Probable glutathione peroxidase 4", "gene_name": "GPX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGASASVPERSVHQFTVKDSSGKDLNMSIYQGKVLLIVNVASKCGFTETNYTQLTELYRKYKDQDFEILAFPCNQFLYQEPGTSQEAHEFACERFKAEYPVFQKVRVNGQNAAPIYKFLKASKPTFLGSRIKWNFTKFLVGKDGLVIDRYGTMVTPLSIEKDIKKALEDA", "length": 170 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8TED1-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "GPX8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL", "length": 209 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7B7-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "Gpx8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPFAAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPRTNSFYSFEVKDAKGRTVSLEKFKGKASLVVNVASDCRFTDKSYQTLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARQNYGVTFPIFHKIKILGPEAEPAFRFIVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "length": 209 }, "evidence": [ { "id": "R4GGB2", "url": "https://omabrowser.org/oma/group/R4GGB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "R4GGB2", "url": "https://www.uniprot.org/uniprotkb/R4GGB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16833", "name": "", "equation": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AGF3-1", "A0A8V0X453-1", "A0A8V0YZM3-1", "A0A8V0YPP2-1" ], "evidence": [ { "id": "16833", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16833" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X453", "gene_name": "CP", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.16.3.4", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "A0A8V0X453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X453" } ] } ] }, { "uniprot_ac": "A0A8V0YPP2", "gene_name": "GPX3", "activity": [ { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A8V0YPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP2" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "A0A8V0YPP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP2" } ] } ] }, { "uniprot_ac": "A0A8V0YZM3", "gene_name": "HEPH", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.16.3.4", "activity": "", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "A0A8V0YZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM3" } ] } ] }, { "uniprot_ac": "A0A8V1AGF3", "gene_name": "GPX1", "activity": [ { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A8V1AGF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGF3" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "A0A8V1AGF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGF3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GGB2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 210, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GGB2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GGB2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGB8-1", "uniprot_ac": "R4GGB8", "uniprot_id": "R4GGB8_CHICK", "mass": { "chemical_mass": 78333.0, "monoisotopic_mass": 78333.0 }, "refseq": { "ac": "NP_001264292", "name": "GAS2-like protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264292" }, "gene_names": [ { "name": "GAS2L3", "type": "recommended", "evidence": [ { "id": "R4GGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ] }, { "name": "GAS2L3", "type": "synonym", "evidence": [ { "id": "NP_001264292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264292" } ] } ], "protein_names": [ { "name": "GAS2-like protein 3", "type": "synonym", "evidence": [ { "id": "NP_001264292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264292" } ] }, { "name": "Growth arrest specific 2 like 3", "type": "synonym", "evidence": [ { "id": "R4GGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGB8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX950275.1, SRR13267648.8983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 5, 2013 this sequence version replaced XP_416172.3. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264292" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GAS2L3", "url": "https://www.uniprot.org/uniprotkb/R4GGB8", "locus": { "chromosome": "1", "start_pos": 47438491, "end_pos": 47421985, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011574", "url": "https://www.ensembl.org/id/ENSGALG00010011574" } ] } } ], "crossref": [ { "id": "R4GGB8", "url": "https://alphafold.ebi.ac.uk/entry/R4GGB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028373", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028373", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417931", "url": "https://www.ncbi.nlm.nih.gov/gene/417931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417931", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDPMSAV", "url": "https://omabrowser.org/oma/group/MDPMSAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GGB8", "url": "https://www.orthodb.org/?gene=R4GGB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46756", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46756", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46756:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46756:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGB8-1", "url": "https://www.uniprot.org/uniprotkb/R4GGB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVTMQNAVQVWFGDDLPLCPRSPLTPRHGPGLADVCLYDQWISVRHEATLVPMQEDLSIWLSGLLGIEVTAEQLLEELDNGVLLCQLIGVLQNTIKKSCSSNNLRNFPMRKVPCKKDAPSGSFFARDNTANFLNWCRAIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLRTSGPASPVNTAKSCCQHGELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRVLQFATLEQKILAFQKGVTSDNISNSPARIQEPPVMNPMSAVNMFQKQPANPPTPVPALKAIHGATAKKPLSKHPQSPALTSPKVPVHASSTAKLLSARPKLTDAQSPFKPLTGTSKKLASPACHSPAPVPSLPASKSSSSTRSRTALVHSETLRKRIRSPDAPKVRFAPAQGSPATGMHSALSASKKQLSQLPATAETLASKQKCVPSKSKPASVTKTKANAVAPRPARLPVTNLRAVAKFAHSQQLYVKPPSENTTQASGSGSQHPRKAPQTASDLARNMKTGSILKHSASVPSLAVSKALKSPPMLGSTSKNVTASVKKTPTTEHLQTPNVNKPPEVGPSSSKTPERTPLSVVRLPQTSAKVAVTKKAVQPSTKSQPSNRDLQANGNMVPAAKKPLSKGKSPTACNKGAPSASKGPLLKSKQDDHYFVMTGSKKPRK", "length": 726, "header": "tr|R4GGB8-1|R4GGB8_CHICK Isoform 1 of Growth arrest specific 2 like 3 OS=Gallus gallus OX=9031 GN=GAS2L3 PE=3 SV=1 CANONICAL=R4GGB8-1" }, "isoforms": [ { "isoform_ac": "R4GGB8-1", "url": "https://www.uniprot.org/uniprotkb/R4GGB8/entry#R4GGB8-1", "sequence": { "sequence": "MQVTMQNAVQVWFGDDLPLCPRSPLTPRHGPGLADVCLYDQWISVRHEATLVPMQEDLSIWLSGLLGIEVTAEQLLEELDNGVLLCQLIGVLQNTIKKSCSSNNLRNFPMRKVPCKKDAPSGSFFARDNTANFLNWCRAIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLRTSGPASPVNTAKSCCQHGELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRVLQFATLEQKILAFQKGVTSDNISNSPARIQEPPVMNPMSAVNMFQKQPANPPTPVPALKAIHGATAKKPLSKHPQSPALTSPKVPVHASSTAKLLSARPKLTDAQSPFKPLTGTSKKLASPACHSPAPVPSLPASKSSSSTRSRTALVHSETLRKRIRSPDAPKVRFAPAQGSPATGMHSALSASKKQLSQLPATAETLASKQKCVPSKSKPASVTKTKANAVAPRPARLPVTNLRAVAKFAHSQQLYVKPPSENTTQASGSGSQHPRKAPQTASDLARNMKTGSILKHSASVPSLAVSKALKSPPMLGSTSKNVTASVKKTPTTEHLQTPNVNKPPEVGPSSSKTPERTPLSVVRLPQTSAKVAVTKKAVQPSTKSQPSNRDLQANGNMVPAAKKPLSKGKSPTACNKGAPSASKGPLLKSKQDDHYFVMTGSKKPRK", "length": 726, "header": "tr|R4GGB8-1|R4GGB8_CHICK Isoform 1 of Growth arrest specific 2 like 3 OS=Gallus gallus OX=9031 GN=GAS2L3 PE=3 SV=1 CANONICAL=R4GGB8-1" }, "locus": { "chromosome": "1", "start_pos": 47437666, "end_pos": 47426385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027696.1", "url": "https://www.ensembl.org/id/ENSGALT00010027696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015876.1", "url": "https://www.ensembl.org/id/ENSGALP00010015876.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417931", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AL26-1", "protein_name": "Growth arrest-specific 2 like 3", "gene_name": "Gas2l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMQPAIQVWFGEDLPLSPRCPLTSRHGPGLADVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIDIKAERLLEELDNGVLLCQLINVLQNMVGAGLSEEPGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRRIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRVVSRYGVEPPVLVKLEKEIELEETLLNTSGLEESISIPKSCCQQEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGEKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNLKPGTPVSVPKGKERQVHRPGACLPASSVKGNLASLSTRSKRPDSPASLLHPKVTSLKGIAKKVNAPSNSALSSLTSLNPAAKPSTAKCASESGRKCVTFPKTPQTKAVPAQNSRDPSKSRLLPSKPPGNIEPKHLKHNHLSSRAESSTCPKLPKGTMQGRPNLSPFQSPAKVTKPSSKTRAIGLGTQSQPPDRTLKSGATSAPRHQSTLNLNNPASVCSGSSANTTQKLKGKSTVSVAKKPPQSKGICPNLGPSSSKSPGRTPLSIVTVPQSAAKSETVSKSAKTAMKGQYSAKGPPKSSKAPASSQNPPSSGKGADSGNKTPTAKKKEEDDHYFVMTGNKKLRK", "length": 678 }, "evidence": [ { "id": "R4GGB8", "url": "https://omabrowser.org/oma/group/R4GGB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MIY4-1", "protein_name": "Growth arrest specific 2 like 3", "gene_name": "GAS2L3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTMLPAIQVWFGEDLPLSPRSPLTPRHGPGLADVCQYDEWIAVRHEATLLPMQEDLSIWLNGLLGIEVKAERLLEELDNGVLLCQLIDVLQNMVKTCNSEEPVNFPMRKVPCKKDAASGSFFARDNTANFLHWCRHIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCQHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSIESVPDSPARTPQPPEMNPLSAVSMFQKQNSKLGTPVGIPRGKEKQVHLPAALPSASSLKGGNLAPRSVRSKLANSPAASSHLKLMSSKGITKKPQAPSNSASSSHASLNPVGKSTFSPAFSRAAPCVSESLRKCISSPSTPKTKRVPAQKSRDVPESTILPNKCSGKTEPKHLKHNHVPSRDHAVSPSATHLNSSSKCPKLPKAHLHVRPNPSSFQSPAKVTTASSKTVIRSLETRAQPHGRAPQAQKPKSALNLNQPLPISSVAPTKAAQKLKDKNMVSVAKKQPQNKSTSQKTGTSASRSPGRTPLSIVSLPQSSAKTQPEPKSVQTATKSQCSAAGPPKSGKAPAPTRKPPSSGKETVSADEKPSAKKKEDDDHYFVMTGSKKPRK", "length": 692 }, "evidence": [ { "id": "R4GGB8", "url": "https://omabrowser.org/oma/group/R4GGB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UWW6-1", "protein_name": "GAS2-like protein 3", "gene_name": "Gas2l3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMQPAIQVWFGEDLPLSPRCPLTPRHGPGLADVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGVDIKAERLLEELDNGVLLCQLINVLQNMVKGCHSDEPGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRHIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNASGLEESISIPKSCCQQEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGEKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPKPPEMNPLSAVNMFQKQNLRPGTPVSVPKNKEKQVRLPGARLPASSVKGNLASPSTRAKRPDSPASFPHPKVTSLKDAAKKTTAPSNSVSQSLASPNPGSKPSTAQCASESSRKCVTFPKTAQTKAIPAQNSRDLSKSRLLPSKSPGKMEPKHLKHNHLSSRDESRINLSSKSPKLPKGAMHGRPNPSPFQPPAKVTKPSSKTGAIGLGTQSQPPTRTPRSGAVSAQRLQSTLNLNSPASVCSGSSAKATQGSKGKNTVSVAKKQPQSKGVCRNPGPGSSKSPGRTPLSIVTVPQSATKTETVSKSAKTAMKGQYSAKGPPKSSKPPTSFRDPPSSGKGADSGDKMPTARKKEEDDHYFVMTGNKKLRK", "length": 683 }, "evidence": [ { "id": "R4GGB8", "url": "https://omabrowser.org/oma/group/R4GGB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XJ1-1", "protein_name": "GAS2-like protein 3", "gene_name": "GAS2L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK", "length": 694 }, "evidence": [ { "id": "R4GGB8", "url": "https://omabrowser.org/oma/group/R4GGB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" }, { "name": "actin crosslink formation", "id": "GO:0051764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051764", "evidence": [ { "database": "UniProtKB", "id": "R4GGB8", "url": "https://www.uniprot.org/uniprotkb/R4GGB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GGB8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 726, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GGB8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GGB8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 601, "end_pos": 603 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGE5-1", "uniprot_ac": "R4GGE5", "uniprot_id": "R4GGE5_CHICK", "mass": { "chemical_mass": 37406.0, "monoisotopic_mass": 37406.0 }, "refseq": { "ac": "XP_025010336", "name": "ALX homeobox protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010336" }, "gene_names": [ { "name": "ALX1", "type": "recommended", "evidence": [ { "id": "R4GGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ] }, { "name": "ALX1", "type": "synonym", "evidence": [ { "id": "XP_025010336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010336" } ] } ], "protein_names": [ { "name": "ALX homeobox protein 1", "type": "recommended", "evidence": [ { "id": "R4GGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGE5/entry#names_and_taxonomy" } ] }, { "name": "ALX homeobox protein 1", "type": "synonym", "evidence": [ { "id": "XP_025010336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010336" } ] }, { "name": "Cartilage homeoprotein 1", "type": "synonym", "evidence": [ { "id": "R4GGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGE5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010336" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALX1", "url": "https://www.uniprot.org/uniprotkb/R4GGE5", "locus": { "chromosome": "1", "start_pos": 41937639, "end_pos": 41914592, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011243", "url": "https://www.ensembl.org/id/ENSGALG00010011243" } ] } } ], "crossref": [ { "id": "R4GGE5", "url": "https://alphafold.ebi.ac.uk/entry/R4GGE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027213", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027213", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427871", "url": "https://www.ncbi.nlm.nih.gov/gene/427871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427871", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSPCGDQ", "url": "https://omabrowser.org/oma/group/SSPCGDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GGE5", "url": "https://www.orthodb.org/?gene=R4GGE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329:SF359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329:SF359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGE5-1", "url": "https://www.uniprot.org/uniprotkb/R4GGE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIMDFLSEKFALKSQPSKNSDFYMGAGGTLEHVMETLDNESFYSKTSGSKCVQAFNPLQRAEHHVRLDRTSPCQDNNVNYGITKVEGQPLHTELNRPLDNCNNLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNTASGSVVTSCMIPRDTSSCMTPYSHSPRTDSGYTGFSNHQNQFSHVPLNNFFTDSLLSGATNGHAFETKPEFERRSSSIAVLRMKAKEHAANISWAM", "length": 328, "header": "tr|R4GGE5-1|R4GGE5_CHICK Isoform 1 of ALX homeobox protein 1 OS=Gallus gallus OX=9031 GN=ALX1 PE=3 SV=2 CANONICAL=R4GGE5-1" }, "isoforms": [ { "isoform_ac": "R4GGE5-1", "url": "https://www.uniprot.org/uniprotkb/R4GGE5/entry#R4GGE5-1", "sequence": { "sequence": "MIMDFLSEKFALKSQPSKNSDFYMGAGGTLEHVMETLDNESFYSKTSGSKCVQAFNPLQRAEHHVRLDRTSPCQDNNVNYGITKVEGQPLHTELNRPLDNCNNLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNTASGSVVTSCMIPRDTSSCMTPYSHSPRTDSGYTGFSNHQNQFSHVPLNNFFTDSLLSGATNGHAFETKPEFERRSSSIAVLRMKAKEHAANISWAM", "length": 328, "header": "tr|R4GGE5-1|R4GGE5_CHICK Isoform 1 of ALX homeobox protein 1 OS=Gallus gallus OX=9031 GN=ALX1 PE=3 SV=2 CANONICAL=R4GGE5-1" }, "locus": { "chromosome": "1", "start_pos": 41936168, "end_pos": 41917198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026842.1", "url": "https://www.ensembl.org/id/ENSGALT00010026842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015296.1", "url": "https://www.ensembl.org/id/ENSGALP00010015296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427871", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYX1-1", "protein_name": "ALX homeobox protein 1", "gene_name": "ALX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYLGAGGALEHVMESLDNESFYSKASAGKCVQAFGPLPRAEHHVRLERTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNSLRMSPVKGMPEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVPSCMLPRDTSSCVTPYAHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLSGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "R4GGE5", "url": "https://omabrowser.org/oma/group/R4GGE5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15699-1", "protein_name": "ALX homeobox protein 1", "gene_name": "ALX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGAGGPLEHVMETLDNESFYSKASAGKCVQAFGPLPRAEHHVRLERTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDTSSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "R4GGE5", "url": "https://omabrowser.org/oma/group/R4GGE5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LVQ7-1", "protein_name": "ALX homeobox protein 1", "gene_name": "alx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEYLSDKFSLKSPAIKGSDYYMDQVMDTLDNVQYYNKASPKCVQAFPMQSNDQHSSMDRSSPCDNQSSVTYCAPKSEESSLHAMENCCSLRVSPATSGPDKTDLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISMLPRTDSYSQISNNLWTGPSAGSSVVSSCMIPRGSPPCVTSPYPHSPRAAEHGYVGFPNHQQNQFGVNHVSLNNFFADSLLASSANSHAAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 320 }, "evidence": [ { "id": "R4GGE5", "url": "https://omabrowser.org/oma/group/R4GGE5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63087-1", "protein_name": "ALX homeobox protein 1", "gene_name": "Alx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGTGGALEHVMETLDNESFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQDSSVNYGITKVEGQPLHTELNRAMDGCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNTSGGSVVTSCMLPRDASSCMTPYSHSPRTDSSYTGFSNHQNQFGHVPLNNFFTDSLLTGTTNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "R4GGE5", "url": "https://omabrowser.org/oma/group/R4GGE5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C8B0-1", "protein_name": "ALX homeobox protein 1", "gene_name": "Alx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGTGGALEHVMETLDNESFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDASSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "R4GGE5", "url": "https://omabrowser.org/oma/group/R4GGE5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "R4GGE5", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GGE5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 328, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GGE5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GGE5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGE5" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 134, "end_pos": 193, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GGJ0-1", "uniprot_ac": "R4GGJ0", "uniprot_id": "R4GGJ0_CHICK", "mass": { "chemical_mass": 16413.0, "monoisotopic_mass": 16413.0 }, "refseq": { "ac": "XP_416113", "name": "40S ribosomal protein S16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416113" }, "gene_names": [ { "name": "RPS16", "type": "recommended", "evidence": [ { "id": "R4GGJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGJ0" } ] }, { "name": "RPS16", "type": "synonym", "evidence": [ { "id": "XP_416113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416113" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS9", "type": "recommended", "evidence": [ { "id": "R4GGJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGJ0/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S16", "type": "synonym", "evidence": [ { "id": "XP_416113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416113" }, { "id": "R4GGJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GGJ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416113" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGJ0", "url": "https://www.uniprot.org/uniprotkb/R4GGJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS16", "url": "https://www.uniprot.org/uniprotkb/R4GGJ0", "locus": { "chromosome": "1", "start_pos": 39852065, "end_pos": 39846391, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013358", "url": "https://www.ensembl.org/id/ENSGALG00010013358" } ] } } ], "crossref": [ { "id": "R4GGJ0", "url": "https://alphafold.ebi.ac.uk/entry/R4GGJ0", "database": "AlphaFoldDB", "categories": 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137369" } ] }, { "annotation": "Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.", "evidence": [ { "database": "UniProtKB", "id": "R4GGR6", "url": "https://www.uniprot.org/uniprotkb/R4GGR6#function" }, { "database": "UniProtKB", "id": "ARBA00055358", "url": "https://www.uniprot.org/uniprotkb/ARBA00055358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GGR6", "url": "https://www.uniprot.org/uniprotkb/R4GGR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL4A", "url": "https://www.uniprot.org/uniprotkb/R4GGR6", "locus": { "chromosome": "2", "start_pos": 26934644, "end_pos": 26702653, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004029", "url": "https://www.ensembl.org/id/ENSGALG00010004029" } ] } } ], "crossref": [ { "id": "ENSGALG00000027757", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420589", "url": "https://www.ncbi.nlm.nih.gov/gene/420589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": 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"https://www.uniprot.org/uniprotkb/R4GGR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGR6-1", "url": "https://www.uniprot.org/uniprotkb/R4GGR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNGLSDQTPILSSLPSFQCFHIVILGLDSAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKMLAMSELSSSTPWHLQPTCAIIGDGLKEGLEKLYDMIIKRRKMLRQQKKKR", "length": 200, "header": "tr|R4GGR6-1|R4GGR6_CHICK Isoform 1 of ADP-ribosylation factor-like protein 4A OS=Gallus gallus OX=9031 GN=ARL4A PE=4 SV=1 CANONICAL=R4GGR6-1" }, "isoforms": [ { "isoform_ac": "R4GGR6-1", "url": "https://www.uniprot.org/uniprotkb/R4GGR6/entry#R4GGR6-1", "sequence": { "sequence": "MGNGLSDQTPILSSLPSFQCFHIVILGLDSAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKMLAMSELSSSTPWHLQPTCAIIGDGLKEGLEKLYDMIIKRRKMLRQQKKKR", "length": 200, "header": "tr|R4GGR6-1|R4GGR6_CHICK Isoform 1 of ADP-ribosylation factor-like protein 4A OS=Gallus gallus OX=9031 GN=ARL4A PE=4 SV=1 CANONICAL=R4GGR6-1" }, "locus": { "chromosome": "2", "start_pos": 26704278, "end_pos": 26703679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009309.1", "url": "https://www.ensembl.org/id/ENSGALT00010009309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005496.1", "url": "https://www.ensembl.org/id/ENSGALP00010005496.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P40617-1", "protein_name": "ADP-ribosylation factor-like protein 4A", "gene_name": "ARL4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"evidence": [ { "id": "R4GH47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ] }, { "name": "OTP", "type": "synonym", "evidence": [ { "id": "XP_003643004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643004" } ] } ], "protein_names": [ { "name": "Orthopedia homeobox", "type": "synonym", "evidence": [ { "id": "R4GH47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH47/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein orthopedia isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003643004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643004" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:554220", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:554220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "R4GH47", "url": "https://www.orthodb.org/?gene=R4GH47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46770:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46770:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GH47-1", "url": "https://www.uniprot.org/uniprotkb/R4GH47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDMAPNSDTVEGTTLLPGEDITTVGSNPSSLAVSAKDADKQQGQQGGQNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVTGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT", "length": 325, "header": "tr|R4GH47-1|R4GH47_CHICK Isoform 1 of Orthopedia homeobox OS=Gallus gallus OX=9031 GN=OTP PE=3 SV=1 CANONICAL=R4GH47-1" }, "isoforms": [ { "isoform_ac": "R4GH47-1", "url": "https://www.uniprot.org/uniprotkb/R4GH47/entry#R4GH47-1", "sequence": { "sequence": "MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDMAPNSDTVEGTTLLPGEDITTVGSNPSSLAVSAKDADKQQGQQGGQNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVTGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT", "length": 325, "header": "tr|R4GH47-1|R4GH47_CHICK Isoform 1 of Orthopedia homeobox OS=Gallus gallus OX=9031 GN=OTP PE=3 SV=1 CANONICAL=R4GH47-1" }, "locus": { "chromosome": "Z", "start_pos": 23685266, "end_pos": 23679514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027172.1", "url": "https://www.ensembl.org/id/ENSGALT00010027172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015469.1", "url": "https://www.ensembl.org/id/ENSGALP00010015469.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 178, "start_aa": "Thr", "end_pos": 178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr178", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:554220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:554220", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "R4GH47", "url": "https://www.uniprot.org/uniprotkb/R4GH47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GH47-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 325, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GH47-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GH47" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GH47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH47" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 104, "end_pos": 163, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 178 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 286, "end_pos": 288 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GHB5-1", "uniprot_ac": "R4GHB5", "uniprot_id": "R4GHB5_CHICK", "mass": { "chemical_mass": 41719.0, "monoisotopic_mass": 41719.0 }, "refseq": { "ac": "NP_001265654", "name": "rhomboid-related protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654" }, "gene_names": [ { "name": "RHBDL1", "type": "recommended", "evidence": [ { "id": "R4GHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" } ] }, { "name": "RHBDL1", "type": "synonym", "evidence": [ { "id": "NP_001265654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654" } ] } ], "protein_names": [ { "name": "Rhomboid-related protein 1", "type": "recommended", "evidence": [ { "id": "R4GHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHB5/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.105", "type": "synonym", "evidence": [ { "id": "R4GHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHB5/entry#names_and_taxonomy" } ] }, { "name": "rhomboid, veinlet-like 1", "type": "synonym", "evidence": [ { "id": "NP_001265654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654" } ] }, { "name": "rhomboid-related protein 1", "type": "synonym", "evidence": [ { "id": "NP_001265654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Jul 13, 2013 this sequence version replaced XP_426761.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001265654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654" } ] }, { "annotation": "May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.", "evidence": [ { "database": "UniProtKB", "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5#function" }, { "database": "UniProtKB", "id": "PIRNR037470", "url": "https://www.uniprot.org/uniprotkb/PIRNR037470#function" }, { "database": "UniProtKB", "id": "ARBA00057065", "url": "https://www.uniprot.org/uniprotkb/ARBA00057065#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RHBDL1", "url": "https://www.uniprot.org/uniprotkb/R4GHB5", "locus": { "chromosome": "14", "start_pos": 13152170, "end_pos": 13147900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018303", "url": "https://www.ensembl.org/id/ENSGALG00010018303" } ] } } ], "crossref": [ { "id": "R4GHB5", "url": "https://alphafold.ebi.ac.uk/entry/R4GHB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028345", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "429205", "url": "https://www.ncbi.nlm.nih.gov/gene/429205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429205", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429205", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEGQICY", "url": "https://omabrowser.org/oma/group/EEGQICY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GHB5", "url": "https://www.orthodb.org/?gene=R4GHB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45840:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45840:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001265654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHB5-1", "url": "https://www.uniprot.org/uniprotkb/R4GHB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSSLLQLIQEQLDPENTGFIGVETFASLVHSHELPLDPAKLDMLVALAQGNDEGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDETGLGFYKRFVRYVAYEILPCEMDRRWYFYQHRTCPPPVFMAAVTLTQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISFLYLAGVLAGSLTVSITDMRAPLVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAIVGISMGLTILRSYEESLRDQCGWWVVLLSYGTFLLFAVFWNIFAYDLLGAQIPPPP", "length": 372, "header": "tr|R4GHB5-1|R4GHB5_CHICK Isoform 1 of Rhomboid-related protein 1 OS=Gallus gallus OX=9031 GN=RHBDL1 PE=3 SV=2 CANONICAL=R4GHB5-1" }, "isoforms": [ { "isoform_ac": "R4GHB5-1", "url": "https://www.uniprot.org/uniprotkb/R4GHB5/entry#R4GHB5-1", "sequence": { "sequence": "MDRSSLLQLIQEQLDPENTGFIGVETFASLVHSHELPLDPAKLDMLVALAQGNDEGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDETGLGFYKRFVRYVAYEILPCEMDRRWYFYQHRTCPPPVFMAAVTLTQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISFLYLAGVLAGSLTVSITDMRAPLVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAIVGISMGLTILRSYEESLRDQCGWWVVLLSYGTFLLFAVFWNIFAYDLLGAQIPPPP", "length": 372, "header": "tr|R4GHB5-1|R4GHB5_CHICK Isoform 1 of Rhomboid-related protein 1 OS=Gallus gallus OX=9031 GN=RHBDL1 PE=3 SV=2 CANONICAL=R4GHB5-1" }, "locus": { "chromosome": "14", "start_pos": 13152147, "end_pos": 13147948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044163.1", "url": "https://www.ensembl.org/id/ENSGALT00010044163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026261.1", "url": "https://www.ensembl.org/id/ENSGALP00010026261.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:429205", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429205", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RG54-1", "protein_name": "Rhomboid-related protein 1", "gene_name": "RHBDL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRSSLLQLIQEQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLGVYKRFVRYVAYEILPREVDRHWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGAHIPPPP", "length": 373 }, "evidence": [ { "id": "R4GHB5", "url": "https://omabrowser.org/oma/group/R4GHB5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75783-1", "protein_name": "Rhomboid-related protein 1", "gene_name": "RHBDL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP", "length": 438 }, "evidence": [ { "id": "R4GHB5", "url": "https://omabrowser.org/oma/group/R4GHB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88779-1", "protein_name": "Rhomboid-related protein 1", "gene_name": "Rhbdl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL", "length": 164 }, "evidence": [ { "id": "R4GHB5", "url": "https://omabrowser.org/oma/group/R4GHB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VC82-1", "protein_name": "Rhomboid-related protein 1", "gene_name": "Rhbdl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSSLLQLIQEQQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLSVYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP", "length": 373 }, "evidence": [ { "id": "R4GHB5", "url": "https://omabrowser.org/oma/group/R4GHB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "R4GHB5", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GHB5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 372, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GHB5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GHB5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHB5" }, { "id": "PF01694", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S54 rhomboid", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 327, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.105", "ec_name": "Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.", "evidence": [ { "id": "3.4.21.105", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.105" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GHF6-1", "uniprot_ac": "R4GHF6", "uniprot_id": "R4GHF6_CHICK", "mass": { "chemical_mass": 23127.0, "monoisotopic_mass": 23127.0 }, "refseq": { "ac": "XP_004949356", "name": "macrophage immunometabolism regulator", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949356" }, "gene_names": [ { "name": "MACIR", "type": "recommended", "evidence": [ { "id": "R4GHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ] }, { "name": "MACIR", "type": "synonym", "evidence": [ { "id": "XP_004949356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949356" } ] } ], "protein_names": [ { "name": "Macrophage immunometabolism regulator", "type": "recommended", "evidence": [ { "id": "R4GHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHF6/entry#names_and_taxonomy" } ] }, { "name": "macrophage immunometabolism regulator", "type": "synonym", "evidence": [ { "id": "XP_004949356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949356" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949356" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MACIR", "url": "https://www.uniprot.org/uniprotkb/R4GHF6", "locus": { "chromosome": "Z", "start_pos": 50625162, "end_pos": 50636328, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008373", "url": "https://www.ensembl.org/id/ENSGALG00010008373" } ] } } ], "crossref": [ { "id": "ENSGALG00000027512", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768501", "url": "https://www.ncbi.nlm.nih.gov/gene/768501", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768501", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768501", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAHKCTG", "url": "https://omabrowser.org/oma/group/LAHKCTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GHF6", "url": "https://www.orthodb.org/?gene=R4GHF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31224:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31224:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHF6-1", "url": "https://www.uniprot.org/uniprotkb/R4GHF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVDINGESRSAISTLPVPMAEVSAAGRTEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFATGEELLKLAQKCTGNEESKGESGPNLRSKQLDSGLARSSRLYKARSRYYQPYEIPAVNGRRRRRMPSSGDKCTKALPHEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRMFARNNT", "length": 207, "header": "tr|R4GHF6-1|R4GHF6_CHICK Isoform 1 of Macrophage immunometabolism regulator OS=Gallus gallus OX=9031 GN=MACIR PE=3 SV=1 CANONICAL=R4GHF6-1" }, "isoforms": [ { "isoform_ac": "R4GHF6-1", "url": "https://www.uniprot.org/uniprotkb/R4GHF6/entry#R4GHF6-1", "sequence": { "sequence": "MEVDINGESRSAISTLPVPMAEVSAAGRTEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFATGEELLKLAQKCTGNEESKGESGPNLRSKQLDSGLARSSRLYKARSRYYQPYEIPAVNGRRRRRMPSSGDKCTKALPHEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRMFARNNT", "length": 207, "header": "tr|R4GHF6-1|R4GHF6_CHICK Isoform 1 of Macrophage immunometabolism regulator OS=Gallus gallus OX=9031 GN=MACIR PE=3 SV=1 CANONICAL=R4GHF6-1" }, "locus": { "chromosome": "Z", "start_pos": 50628217, "end_pos": 50627597, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020045.1", "url": "https://www.ensembl.org/id/ENSGALT00010020045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011593.1", "url": "https://www.ensembl.org/id/ENSGALP00010011593.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768501", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768501", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B3DHS1-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "macir", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMDASGASRAPISVLPAAEVKSTLKPEADKPRCSSTPCSPIKSTVSGYQILHMNSNYLVGFTTGEELLKLAQKWSSPDSSNTEALPSPIKKPVDLGLHRASRIYKAKSRYYQPYDIPAVNGRRRRRMPSSGDSCLKSIVSGEPSKALHGPLPLCLLKGKRVYSKSLDYLNLDKMSLREPVDTEVLQYQLQHLNLRGERVFTRNKT", "length": 206 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZPS9-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "Macir", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMDVNGEPRSTLTTLPLPAAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPPLRSRQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 207 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HQD1-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "Macir", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVDINGESRSTLTTLPLPVAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFATGEELLKLAQKCTGGEESQGEAMPPFRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 207 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LQ30-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "MACIR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVDVNGESRSTLTSLPLPVAEASSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKGEAVPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 207 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZBS1-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "MACIR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVDVNGESRSALTTLPLPVAEASSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGAEESKGEAVPSLRSKQLDVGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 207 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VEB3-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "Macir", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVDINGDSRSTLTTLPLPVAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPALRAKQLDTGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKPLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 207 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GV9-1", "protein_name": "Macrophage immunometabolism regulator", "gene_name": "MACIR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "length": 206 }, "evidence": [ { "id": "R4GHF6", "url": "https://omabrowser.org/oma/group/R4GHF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of fibroblast migration", "id": "GO:0010764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010764", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "R4GHF6", "url": "https://www.uniprot.org/uniprotkb/R4GHF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GHJ0-1", "uniprot_ac": "R4GHJ0", "uniprot_id": "R4GHJ0_CHICK", "mass": { "chemical_mass": 42550.0, "monoisotopic_mass": 42550.0 }, "refseq": { "ac": "XP_004936473", "name": "probable G-protein coupled receptor 132", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936473" }, "gene_names": [ { "name": "GPR132", "type": "recommended", "evidence": [ { "id": "R4GHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ] }, { "name": "GPR132", "type": "synonym", "evidence": [ { "id": "XP_004936473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936473" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 132", "type": "synonym", "evidence": [ { "id": "R4GHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 132", "type": "synonym", "evidence": [ { "id": "XP_004936473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936473" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936473" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR132", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0", "locus": {} } ], "crossref": [ { "id": "R4GHJ0", "url": "https://alphafold.ebi.ac.uk/entry/R4GHJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027407", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027407", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859188", "url": "https://www.ncbi.nlm.nih.gov/gene/100859188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859188", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLCELMY", "url": "https://omabrowser.org/oma/group/SLCELMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GHJ0", "url": "https://www.orthodb.org/?gene=R4GHJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373076", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GHJ0-1", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPHLIRNENTSWEKKIIMGDHNVCATIGKDNNSTICSNIPYEDTKILVIVVYSIVFAIGLPANCLTSMLALVQIRRNNAIAIYIFSLSLCDLMYLSTLPLWIIYAQQNHQWTMGEQVCKLTGFVFFCNIYISILLLCCISLDRYVALVYALESRGRRGRKKAIIIVCFLVAAVAVIHSPVFHMNSIHNSNCFETLPLDKTLASFSFARFLFGFVIPFTVLIFTNYKIFQRTKTSDSVTSHQKAKVKYLAIAIIVIFLMCFAPYHVVLLIRAIYFMFHQDCSCPFERSIYSVFTAFLCLSTANGIADPIIYVLTSENVRKDFYRGLRRWKSNSSRLNSSINHKTDSSKLKMQKESQEGVLEEENKEISSSSQV", "length": 373, "header": "tr|R4GHJ0-1|R4GHJ0_CHICK Isoform 1 of G protein-coupled receptor 132 OS=Gallus gallus OX=9031 GN=GPR132 PE=3 SV=1 CANONICAL=R4GHJ0-1" }, "isoforms": [ { "isoform_ac": "R4GHJ0-1", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0/entry#R4GHJ0-1", "sequence": { "sequence": "MFPHLIRNENTSWEKKIIMGDHNVCATIGKDNNSTICSNIPYEDTKILVIVVYSIVFAIGLPANCLTSMLALVQIRRNNAIAIYIFSLSLCDLMYLSTLPLWIIYAQQNHQWTMGEQVCKLTGFVFFCNIYISILLLCCISLDRYVALVYALESRGRRGRKKAIIIVCFLVAAVAVIHSPVFHMNSIHNSNCFETLPLDKTLASFSFARFLFGFVIPFTVLIFTNYKIFQRTKTSDSVTSHQKAKVKYLAIAIIVIFLMCFAPYHVVLLIRAIYFMFHQDCSCPFERSIYSVFTAFLCLSTANGIADPIIYVLTSENVRKDFYRGLRRWKSNSSRLNSSINHKTDSSKLKMQKESQEGVLEEENKEISSSSQV", "length": 373, "header": "tr|R4GHJ0-1|R4GHJ0_CHICK Isoform 1 of G protein-coupled receptor 132 OS=Gallus gallus OX=9031 GN=GPR132 PE=3 SV=1 CANONICAL=R4GHJ0-1" }, "locus": { "chromosome": "5", "start_pos": 51483247, "end_pos": 51481670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047861.1", "url": "https://www.ensembl.org/id/ENSGALT00010047861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028289.1", "url": "https://www.ensembl.org/id/ENSGALP00010028289.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859188", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859188", "resource": "KEGG Pathway" }, { "id": "R-GGA-373076", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "resource": "Reactome", "description": "Class A/1 (Rhodopsin-like receptors)" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IEK2-1", "protein_name": "Probable G-protein coupled receptor 132b", "gene_name": "gpr132b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSGRVLTTFRDMMHATTVAQSIMTSMNQSSRASCEISHEADRIPLMVLYIVVFIIGLPANLATVYLTLHQVCRKNVLGIYLLSLSICDLTYLFTLPMWTVYVSRNHEWPWSSLACKITGFVFFNNMYISIFLLCCVSIDRYVAVVYAIESRGLRQKRIAAFVSFLIFIVVGLGHSPVFIMREGQVEEGSHRCFEPSQSTTLVTGFNYARVCIGFCIPLAILIFTNRAILANVQASTGLQPHQKVKVRYLAVAVVALFLICFAPYHIILLMRAVIFHFPNLQGKCHFEQHIYTPYKISLGLSTFNSAINPILYVLSSNNIRQEIRRGITSVCDRVLSSQRSTHSSQHNMHSSRSNSEPFPIKGGQMRTVCPTA", "length": 373 }, "evidence": [ { "id": "R4GHJ0", "url": "https://omabrowser.org/oma/group/R4GHJ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287B0M2-1", "protein_name": "G protein-coupled receptor 132", "gene_name": "GPR132", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPLTWELPYGTGAAPPKKDRPKGTPRGSATLGVSSLGPREPSCLPWRGRLWVARRGAGPHACLCPAGNATPAGGPGLAALNCSMPFEESRLFLVAVYSAVCVLGLPANCLTAWLTLLQVLQGNVLAVYLFCLALCELLYVGTLPLWVVYVQNQHRWTLGPWACRVTAYIFFCNLYVSILFLCCISCDRFVAVVYALESRGRRHQRTAILVSAAVFALVGLVHYPVFQMGEGDTCFETLPMDRKAAGFYYARFTVGFALPLGIIAFTNQRIFRSSQLSASLSAAQKAKVKHLAIAVVAIFLVCFAPYHLVLLVKAVAFSYHQGDPGSMCAFEASLYTASMVLLCLSTVNSIADPFIYVLAAEVSRQEVSRLHKEWKKWSTKTDDIKLTSSKDSEEAASPVSLRNGCVGPGPVWPSGPPPGTLERLTEESC", "length": 430 }, "evidence": [ { "id": "R4GHJ0", "url": "https://omabrowser.org/oma/group/R4GHJ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7JRI9-1", "protein_name": "Probable G-protein coupled receptor 132 isoform X1", "gene_name": "Gpr132", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQQSLQGVLVLVLANKQDLVEKRPSAHKLAVLLSCQSHPHKGHKAHIGSTMRSESIGAAGNSTPGVPSILLTVSVPSSKVCRPSYEESRVVLVVVYSAVCMLGLPANCLTAWLTLLQVLQRNVLAVYLFFLSVCELLYIGTLPLWIIYIENEHRWSLGPQACKVTAYVFFCNIYISILLLCCISCDRYMAVVYALESRGHRHQKTAIIVSVIVFVLVGLVNYPVFDIKMERNSCFEPLDMNSKIASYHYLRFAFGFAIPLGTLAFTNHRIFRSIKLSSSLSTSQKAKVKHSAVAVVTIFLVCFAPYHLVLLIKAVSFSIIGGDEDAVCAFESRLYTVSVVFLCLSTVNSVADPIIYVLATDHSRQEVSRIHTGWKKWSTKTYLTDFKNSEETHLPTALTNSYTFPKPVHPPGSQLAELDQLDLRCSPERLPEEFC", "length": 436 }, "evidence": [ { "id": "R4GHJ0", "url": "https://omabrowser.org/oma/group/R4GHJ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9UNW8-1", "protein_name": "Probable G protein-coupled receptor 132", "gene_name": "GPR132", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCPMLLKNGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFSRPVHPPGSPCPAKRLIEESC", "length": 380 }, "evidence": [ { "id": "R4GHJ0", "url": "https://omabrowser.org/oma/group/R4GHJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z282-1", "protein_name": "Probable G protein-coupled receptor 132", "gene_name": "Gpr132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSEPTNAAGNTTLGVTSVLQSTSVPSSETCHVSYEESRVVLVVVYSAVCLLGLPANCLTAWLTLLQVLQRNVLAVYLFCLSLCELLYISTVPLWIIYIQNQHKWNLGPQACKVTAYIFFCNIYISILLLCCISCDRYMAVVYALESRGHRHQRTAVTISACVILLVGLVNYPVFDMKVEKSFCFEPLRMNSKIAGYHYLRFTFGFAIPLGILAFTNHQIFRSIKLSDSLSAAQKNKVKRSAIAVVTIFLVCFAPYHVVLLVKAASFSFYQGDMDAVCAFESRLYTVSMVFLCLSTVNSVADPIIYVLGTDHSRQEVSRIHTGWKKWSTKTYVTCSKDSEETHLPTELSNTYTFPNPAHPPGSQPAKLGLLCSPERLPEELC", "length": 382 }, "evidence": [ { "id": "R4GHJ0", "url": "https://omabrowser.org/oma/group/R4GHJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "R4GHJ0", "url": "https://www.uniprot.org/uniprotkb/R4GHJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { 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[ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On or before Dec 6, 2021 this sequence version replaced XP_040562348.1, NP_001107977.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001107977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107977" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GI13", "url": "https://www.uniprot.org/uniprotkb/R4GI13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPLX3", "url": "https://www.uniprot.org/uniprotkb/R4GI13", "locus": { "chromosome": "10", "start_pos": 2445218, "end_pos": 2448403, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023531", "url": "https://www.ensembl.org/id/ENSGALG00010023531" } ] } } ], "crossref": [ { "id": "R4GI13", "url": "https://alphafold.ebi.ac.uk/entry/R4GI13", "database": "AlphaFoldDB", 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"name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "R4GI13", "url": "https://www.uniprot.org/uniprotkb/R4GI13" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031630", "evidence": [ { "database": "UniProtKB", "id": "R4GI13", "url": "https://www.uniprot.org/uniprotkb/R4GI13" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "R4GI13", "url": "https://www.uniprot.org/uniprotkb/R4GI13" } ], "pmid": "" }, { "name": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "id": "GO:0099069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099069", "evidence": [ { "database": "UniProtKB", "id": "R4GI13", "url": 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"glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI14/entry#names_and_taxonomy" } ] }, { "name": "B-cell CLL/lymphoma 10", "type": "synonym", "evidence": [ { "id": "NP_001188416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" }, { "id": "R4GI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI14/entry#names_and_taxonomy" } ] }, { "name": "B-cell lymophoma 10 protein", "type": "synonym", "evidence": [ { "id": "NP_001188416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" } ] }, { "name": "B-cell lymphoma/leukemia 10", "type": "synonym", "evidence": [ { "id": "NP_001188416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267648.16740.1, HAEK01145831.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Apr 21, 2011 this sequence version replaced NP_001188416.1. Sequence Note: This RefSeq record was created from transcripts of different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" } ] }, { "annotation": "Clustal W alignment of orthologous regions of Bcl10 from various mammals (mouse, human, and rat), birds (chicken), and fish (fugu) from amino acids 79-104 of the mouse sequence was done, to identify conserved residues and structural modeling of the Bcl", "evidence": [ { "database": "RefSeq", "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" }, { "database": "PubMed", "id": "18806265", "url": "https://glygen.org/publication/PubMed/18806265" } ] }, { "annotation": "IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells", "evidence": [ { "database": "RefSeq", "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" }, { "database": "PubMed", "id": "18086859", "url": "https://glygen.org/publication/PubMed/18086859" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCL10", "url": "https://www.uniprot.org/uniprotkb/R4GI14", "locus": { "chromosome": "8", "start_pos": 16021904, "end_pos": 16014015, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020681", "url": "https://www.ensembl.org/id/ENSGALG00010020681" } ] } } ], "crossref": [ { "id": "R4GI14", "url": "https://alphafold.ebi.ac.uk/entry/R4GI14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028935", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028935", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08810", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08810", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424528", "url": "https://www.ncbi.nlm.nih.gov/gene/424528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424528", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424528", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPDGEQS", "url": "https://omabrowser.org/oma/group/HPDGEQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GI14", "url": "https://www.orthodb.org/?gene=R4GI14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34920:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34920:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1169091", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-202424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5607764", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI14-1", "url": "https://www.uniprot.org/uniprotkb/R4GI14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVSGPASSAVGRPLTEDEMADVKKEALERMRPYLCDKIIAERHFDYLRSKKILTREDTEEISSRSSSRKKTGKLLDYLAENPKGLDALVESIRRERTQNFLLQKITDIVLKVKNEKLEALKGLSCSTCMTSLYGGTNNLSRSYSDESNFFDKTKDKESTQMHNPEEDYSTAAFMSAVSLHSMNLPVAEMGNAESAVFSVTLPGPGDPGAPPLPPELQSEQQEPCTSSSDNCFLPLRSRSLHPQ", "length": 244, "header": "tr|R4GI14-1|R4GI14_CHICK Isoform 1 of B-cell lymphoma/leukemia 10 OS=Gallus gallus OX=9031 GN=BCL10 PE=4 SV=1 CANONICAL=R4GI14-1" }, "isoforms": [ { "isoform_ac": "R4GI14-1", "url": "https://www.uniprot.org/uniprotkb/R4GI14/entry#R4GI14-1", "sequence": { "sequence": "MEVSGPASSAVGRPLTEDEMADVKKEALERMRPYLCDKIIAERHFDYLRSKKILTREDTEEISSRSSSRKKTGKLLDYLAENPKGLDALVESIRRERTQNFLLQKITDIVLKVKNEKLEALKGLSCSTCMTSLYGGTNNLSRSYSDESNFFDKTKDKESTQMHNPEEDYSTAAFMSAVSLHSMNLPVAEMGNAESAVFSVTLPGPGDPGAPPLPPELQSEQQEPCTSSSDNCFLPLRSRSLHPQ", "length": 244, "header": "tr|R4GI14-1|R4GI14_CHICK Isoform 1 of B-cell lymphoma/leukemia 10 OS=Gallus gallus OX=9031 GN=BCL10 PE=4 SV=1 CANONICAL=R4GI14-1" }, "locus": { "chromosome": "8", "start_pos": 16019852, "end_pos": 16014077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049957.1", "url": "https://www.ensembl.org/id/ENSGALT00010049957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029508.1", "url": "https://www.ensembl.org/id/ENSGALP00010029508.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells.", "journal": "The Journal of experimental medicine", "date": "2007-12-24", "authors": "Shinohara Hisaaki, Maeda Shiori, Watarai Hiroshi, Kurosaki Tomohiro", "evidence": [ { "database": "RefSeq", "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" } ], "reference": [ { "type": "PubMed", "id": "18086859", "url": "https://glygen.org/publication/PubMed/18086859" } ] }, { "title": "Multiple protein domains mediate interaction between Bcl10 and MALT1.", "journal": "The Journal of biological chemistry", "date": "2008-11-21", "authors": "Langel Felicia D, Jain Nidhi A, Rossman Jeremy S, Kingeter Lara M, Kashyap Anuj K, Schaefer Brian C", "evidence": [ { "database": "RefSeq", "id": "NP_001188416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188416" } ], "reference": [ { "type": "PubMed", "id": "18806265", "url": "https://glygen.org/publication/PubMed/18806265" } ] } ], "pathway": [ { "id": "gga:424528", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424528", "resource": "KEGG Pathway" }, { "id": "R-GGA-1169091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "resource": "Reactome", "description": "Activation of NF-kappaB in B cells" }, { "id": "R-GGA-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-GGA-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-GGA-5607764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "resource": "Reactome", "description": "CLEC7A (Dectin-1) signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F8A6-1", "protein_name": "B-cell lymphoma/leukemia 10", "gene_name": "bcl10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVTHLTEDEMADIKKEAIERLRPYLVDKIIADRHFDYLRSKKILTREDTEEISCRTTRGKRTSKLLDILAENPRGLDMLIESIKWGRTLNFIIARITDEVQRVKNERLEALKAGSNSAYPTTKGATNDFSKMDSDYDKYSTMCLHPEGEASSSSSVATGSFNLRYSSTRGNEALMVSGGSGTMNVSSTSSILPKPGDPGAPALPEEMENDEQDMDGGVCKSAGSSGDANFQPLRSRSLSP", "length": 241 }, "evidence": [ { "id": "R4GI14", "url": "https://omabrowser.org/oma/group/R4GI14/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IMU1-1", "protein_name": "B-cell lymphoma/leukemia 10", "gene_name": "Bcl10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLQCSSCEPFAAGATNNLSRSNSEESNLSEKQRASTVMYHPEGESSTAPFFSTESSLNLPVLEVGRTENGSFSSGTLPRPGDPGAPPLPPDLRLEGGTYGNSSEMFLPLRSRALSRQ", "length": 232 }, "evidence": [ { "id": "R4GI14", "url": "https://omabrowser.org/oma/group/R4GI14/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95999-1", "protein_name": "B-cell lymphoma/leukemia 10", "gene_name": "BCL10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ", "length": 233 }, "evidence": [ { "id": "R4GI14", "url": "https://omabrowser.org/oma/group/R4GI14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYN5-1", "protein_name": "B-cell lymphoma/leukemia 10", "gene_name": "Bcl10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRSNSDESNFSEKQRPSTVIYHPEGESSTAPFFSTESSLNLPVLEVGRLENSSFSSASLPRPGDPGAPPLPPDLRLEEGGSCGNSSEMFLPLRSRALSRQ", "length": 233 }, "evidence": [ { "id": "R4GI14", "url": "https://omabrowser.org/oma/group/R4GI14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z0H7-1", "protein_name": "B-cell lymphoma/leukemia 10", "gene_name": "Bcl10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPRGLDTLVESIRREKTQSFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRCNSDESNLSEKQRASTVMYHPEGESSTAPFFSMASSLNLPVLEVGRTENSSFSSATLPRPGDPGAPPLPPDLRLEEGGSCGNSSEMFLPLRSRALSRQ", "length": 233 }, "evidence": [ { "id": "R4GI14", "url": "https://omabrowser.org/oma/group/R4GI14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "protein kinase B binding", "id": "GO:0043422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043422", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "CBM complex", "id": "GO:0032449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032449", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" }, { "name": "positive regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001238", "evidence": [ { "database": "UniProtKB", "id": "R4GI14", "url": "https://www.uniprot.org/uniprotkb/R4GI14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GI14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GI14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GI14" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI14" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 94, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GI61-1", "uniprot_ac": "R4GI61", "uniprot_id": "R4GI61_CHICK", "mass": { "chemical_mass": 58223.0, "monoisotopic_mass": 58223.0 }, "refseq": { "ac": "NP_001264588", "name": "dolichol kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" }, "gene_names": [ { "name": "DOLK", "type": "recommended", "evidence": [ { "id": "R4GI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ] }, { "name": "DOLK", "type": "synonym", "evidence": [ { "id": "NP_001264588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" } ] }, { "name": "TMEM15", "type": "synonym", "evidence": [ { "id": "NP_001264588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" } ] } ], "protein_names": [ { "name": "dolichol kinase", "type": "recommended", "evidence": [ { "id": "R4GI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI61/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.108", "type": "synonym", "evidence": [ { "id": "R4GI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI61/entry#names_and_taxonomy" } ] }, { "name": "dolichol kinase", "type": "synonym", "evidence": [ { "id": "NP_001264588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" } ] }, { "name": "transmembrane protein 15", "type": "synonym", "evidence": [ { "id": "NP_001264588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX933950.1, HAEK01014463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Sep 23, 2021 this sequence version replaced NP_001264588.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264588", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DOLK", "url": "https://www.uniprot.org/uniprotkb/R4GI61", "locus": { "chromosome": "17", "start_pos": 5994885, "end_pos": 6005591, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028593", "url": "https://www.ensembl.org/id/ENSGALG00010028593" } ] } } ], "crossref": [ { "id": "ENSGALG00000026007", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417199", "url": "https://www.ncbi.nlm.nih.gov/gene/417199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417199", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIHWPGT", "url": "https://omabrowser.org/oma/group/EIHWPGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GI61", "url": "https://www.orthodb.org/?gene=R4GI61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13205:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13205:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446199", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446199", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264588", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI61-1", "url": "https://www.uniprot.org/uniprotkb/R4GI61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNKPVLVESLIVFSIVLCVHAVVWDRYSWCAVALAIQAFYVQFKWDRLLQQGGAVFQFRTTANSGLLPASMVIPLLGIAMKERCKAAGIVYFERFGIVVASTGMLVALFLSVIAVGITKPVPTNTCILSGVAGSIIIYTMKHSLTVSEVIEVLEVLLIFVYLSMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLNVIEGRGEPIDFFLLVAVIGVVILGLFFTVLFIFMDSGTWISSMFFHMMTAVLGLGVIMPWLYRLIRRNPLFWLLQFLFQTQTRVYLLIYWTLLAASACGIVFYQNAKRSSESKKHQASTITRKYFHFIVVATYVPGLIYDRQLLHVAAVLCLAVFIFLEYIRYFRIKPFGQTLRYLLSLFLDERDSGPLILTHIYLLLGMSLPVWLFPRSCAPKGALSGAGALVPYAGVLAVGVGDTMASVFGSTMGEIKWPGTKKTFEGTMTAIFAQIIAVALILIFDSSVNLNSSYAWILVSVSLVSLLEAYTTQIDNLLLPLYLQIMFMV", "length": 523, "header": "tr|R4GI61-1|R4GI61_CHICK Isoform 1 of dolichol kinase OS=Gallus gallus OX=9031 GN=DOLK PE=3 SV=1 CANONICAL=R4GI61-1" }, "isoforms": [ { "isoform_ac": "R4GI61-1", "url": "https://www.uniprot.org/uniprotkb/R4GI61/entry#R4GI61-1", "sequence": { "sequence": "MLNKPVLVESLIVFSIVLCVHAVVWDRYSWCAVALAIQAFYVQFKWDRLLQQGGAVFQFRTTANSGLLPASMVIPLLGIAMKERCKAAGIVYFERFGIVVASTGMLVALFLSVIAVGITKPVPTNTCILSGVAGSIIIYTMKHSLTVSEVIEVLEVLLIFVYLSMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLNVIEGRGEPIDFFLLVAVIGVVILGLFFTVLFIFMDSGTWISSMFFHMMTAVLGLGVIMPWLYRLIRRNPLFWLLQFLFQTQTRVYLLIYWTLLAASACGIVFYQNAKRSSESKKHQASTITRKYFHFIVVATYVPGLIYDRQLLHVAAVLCLAVFIFLEYIRYFRIKPFGQTLRYLLSLFLDERDSGPLILTHIYLLLGMSLPVWLFPRSCAPKGALSGAGALVPYAGVLAVGVGDTMASVFGSTMGEIKWPGTKKTFEGTMTAIFAQIIAVALILIFDSSVNLNSSYAWILVSVSLVSLLEAYTTQIDNLLLPLYLQIMFMV", "length": 523, "header": "tr|R4GI61-1|R4GI61_CHICK Isoform 1 of dolichol kinase OS=Gallus gallus OX=9031 GN=DOLK PE=3 SV=1 CANONICAL=R4GI61-1" }, "locus": { "chromosome": "17", "start_pos": 5996242, "end_pos": 5994885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069245.1", "url": "https://www.ensembl.org/id/ENSGALT00010069245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042687.1", "url": "https://www.ensembl.org/id/ENSGALP00010042687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417199", "resource": "KEGG Pathway" }, { "id": "R-GGA-446199", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446199", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TP87-1", "protein_name": "dolichol kinase", "gene_name": "DOLK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRECAPPASGSGAPLSGSVLAEAAVVFIVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZLM6-1", "protein_name": "dolichol kinase", "gene_name": "Dolk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRQCPPQAPESGFALSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCLTAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGIIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLATMACLVVLYQNAKRSSSESKKHKAPTITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCAQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 536 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IGZ1-1", "protein_name": "dolichol kinase", "gene_name": "Dolk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTRQCPPPVAESGFPLSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPYFERFGVVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGIIIYIMKHSLSVGEVIEVLEVLLVFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLATMACLVVLYQNAKRSSSESKKHKAPAITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKDSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 536 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q58CR4-1", "protein_name": "Dolichol kinase", "gene_name": "DOLK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTRECAPPTPGSGAPLSGSVLAEAAVVFVVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEALLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWCLLATVACLVVLYQNAKRSSSESKKHQAPTITRKYFHFIVVATYIPGIILDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R2Y3-1", "protein_name": "Dolichol kinase", "gene_name": "Dolk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRQCPPQESGAALSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGVIIYIMRHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLASVACLVVLYQNAKRSSSESKKHRAPTITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKDSLEGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 534 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPQ8-1", "protein_name": "Dolichol kinase", "gene_name": "DOLK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRECPSPAPGPGAPLSGSVLAEAAVVFAVVLSIHATVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPFFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVILGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYLLAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA", "length": 538 }, "evidence": [ { "id": "R4GI61", "url": "https://omabrowser.org/oma/group/R4GI61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichol kinase activity", "id": "GO:0004168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004168", "evidence": [ { "database": "UniProtKB", "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "R4GI61", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-449221" ], "output_participant_list": [ "R-ALL-110094" ], "enzyme_list": [ "R4GI61-1" ], "evidence": [ { "id": "R-GGA-446195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446195" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110094", "participant_name": "CDP [cytosol]", "crossref": [ { "id": "ZINC000008215624", "database": "ZINC", "url": "" }, { "id": "58069", "database": "ChEBI", "url": "" }, { "id": "C00112", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-449221", "participant_name": "DCHOL [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000030320742", "database": "ZINC", "url": "" }, { "id": "ZINC000030320745", "database": "ZINC", "url": "" }, { "id": "HMDB0005176", "database": "HMDB Metabolite", "url": "" }, { "id": "16091", "database": "ChEBI", "url": "" }, { "id": "C00381", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "R4GI61", "gene_name": "DOLK", "activity": [ { "ec_number": "2.7.1.108", "activity": "a di-trans,poly-cis-dolichol + CTP = a di-trans,poly-cis-dolichyl phosphate + CDP + H(+).", "evidence": [ { "id": "R4GI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ] }, { "ec_number": "2.7.1.108", "activity": "", "evidence": [ { "id": "R4GI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GI61" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.108", "ec_name": "a di-trans,poly-cis-dolichol + CTP = a di-trans,poly-cis-dolichyl phosphate + CDP + H(+).", "evidence": [ { "id": "2.7.1.108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.108" }, { "id": "2.7.1.108", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.108" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GIC2-1", "uniprot_ac": "R4GIC2", "uniprot_id": "R4GIC2_CHICK", "mass": { "chemical_mass": 12110.0, "monoisotopic_mass": 12110.0 }, "refseq": { "ac": "NP_001183967", "name": "guanylate cyclase activator 2A (guanylin) precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" }, "gene_names": [ { "name": "GUCA2B", "type": "recommended", "evidence": [ { "id": "R4GIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIC2" } ] }, { "name": "GUCA2A", "type": "synonym", "evidence": [ { "id": "NP_001183967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" } ] }, { "name": "GUCA2B", "type": "synonym", "evidence": [ { "id": "NP_001183967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" } ] } ], "protein_names": [ { "name": "Guanylate cyclase activator 2B", "type": "recommended", "evidence": [ { "id": "R4GIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIC2/entry#names_and_taxonomy" } ] }, { "name": "guanylate cyclase activator 2A (guanylin) precursor", "type": "synonym", "evidence": [ { "id": "NP_001183967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" } ] }, { "name": "guanylate cyclase activator 2A (guanylin)", "type": "synonym", "evidence": [ { "id": "NP_001183967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CF249957.1, CF250954.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000329.1. On Oct 3, 2010 this sequence version replaced XP_417652.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001183967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967" } ] }, { "annotation": "Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.", "evidence": [ { "database": "UniProtKB", "id": "R4GIC2", "url": "https://www.uniprot.org/uniprotkb/R4GIC2#function" }, { "database": "UniProtKB", "id": "ARBA00037765", "url": "https://www.uniprot.org/uniprotkb/ARBA00037765#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GIC2", "url": "https://www.uniprot.org/uniprotkb/R4GIC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GUCA2B", "url": "https://www.uniprot.org/uniprotkb/R4GIC2", "locus": { "chromosome": "21", "start_pos": 5832750, "end_pos": 5826678, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016795", "url": "https://www.ensembl.org/id/ENSGALG00010016795" } ] } } ], "crossref": [ { "id": "R4GIC2", "url": "https://alphafold.ebi.ac.uk/entry/R4GIC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027269", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027269", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419498", "url": "https://www.ncbi.nlm.nih.gov/gene/419498", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419498", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAEPMLP", "url": "https://omabrowser.org/oma/group/CAEPMLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GIC2", "url": "https://www.orthodb.org/?gene=R4GIC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11318:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11318:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001183967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001183967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GIC2", "url": "https://www.uniprot.org/uniprotkb/R4GIC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIC2-1", "url": "https://www.uniprot.org/uniprotkb/R4GIC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGLVSFTVLALLLLVHSSQAVYVQDGNLKFSLESVKKLKELMDENKVINPRIVVAKAGYSPCQDKALPEEFQPVCKREDAPMIFERLCLVASEADLCEICANAACSGCF", "length": 110, "header": "tr|R4GIC2-1|R4GIC2_CHICK Isoform 1 of Guanylate cyclase activator 2B OS=Gallus gallus OX=9031 GN=GUCA2B PE=1 SV=1 CANONICAL=R4GIC2-1" }, "isoforms": [ { "isoform_ac": "R4GIC2-1", "url": "https://www.uniprot.org/uniprotkb/R4GIC2/entry#R4GIC2-1", "sequence": { "sequence": "MRGLVSFTVLALLLLVHSSQAVYVQDGNLKFSLESVKKLKELMDENKVINPRIVVAKAGYSPCQDKALPEEFQPVCKREDAPMIFERLCLVASEADLCEICANAACSGCF", "length": 110, "header": "tr|R4GIC2-1|R4GIC2_CHICK Isoform 1 of Guanylate cyclase activator 2B OS=Gallus gallus OX=9031 GN=GUCA2B PE=1 SV=1 CANONICAL=R4GIC2-1" }, "locus": { "chromosome": "21", "start_pos": 5831843, "end_pos": 5827962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040522.1", "url": "https://www.ensembl.org/id/ENSGALT00010040522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023524.1", "url": "https://www.ensembl.org/id/ENSGALP00010023524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419498", "resource": "KEGG Pathway" }, { "id": "R-GGA-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [ { "uniprot_canonical_ac": "P28902-1", "protein_name": "Guanylin", "gene_name": "Guca2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAWLLSVLCLLGALAVLVEGVTVQDGDLSFPLESVKQLKHLREVQEPTLMSHKKFALRLPKPVAPELCSQSAFPEALRPLCEKPNAEEILQRLEAIAQDPNTCEICAYAACTGC", "length": 115 }, "evidence": [ { "id": "R4GIC2", "url": "https://omabrowser.org/oma/group/R4GIC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33680-1", "protein_name": "Guanylin", "gene_name": "Guca2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNACVLSVLCLLGALAVLVEGVTVQDGDLSFPLESVKKLKGLREVQEPRLVSHKKFAPRLLQPVAPQLCSSHSALPEALRPVCEKPNAEEILQRLEAIAQDPNTCEICAYAACTGC", "length": 116 }, "evidence": [ { "id": "R4GIC2", "url": "https://omabrowser.org/oma/group/R4GIC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P79897-1", "protein_name": "Guanylin", "gene_name": "GUCA2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNTFLFPTLCLLGVWAALAGGVTVKDGEFSFSLESVKKLKDLQELQKPRNPRNLDGPIIPVLCNSPKFPEELKPICQKPNAEEILERLETIAQDPSTCEICAYAACAGC", "length": 109 }, "evidence": [ { "id": "R4GIC2", "url": "https://omabrowser.org/oma/group/R4GIC2/", "database": "OMA" } ], "glygen_name": "Pig", 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"evidence": [ { "database": "UniProtKB", "id": "R4GIC2", "url": "https://www.uniprot.org/uniprotkb/R4GIC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GIC2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 110, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GIC2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GIC2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GIQ2-1", "uniprot_ac": "R4GIQ2", "uniprot_id": "R4GIQ2_CHICK", "mass": { "chemical_mass": 18577.0, "monoisotopic_mass": 18577.0 }, "refseq": { "ac": "XP_001233393", "name": "60S ribosomal protein L21 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233393" }, "gene_names": [ { "name": "RPL21", "type": "recommended", "evidence": [ { "id": "R4GIQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ] }, { "name": "RPL21", "type": "synonym", "evidence": [ { "id": "XP_001233393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233393" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL21", "type": "recommended", "evidence": [ { "id": "R4GIQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L21 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233393" } ] }, { "name": "60S ribosomal protein L21", "type": "synonym", "evidence": [ { "id": "R4GIQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233393" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL21", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2", "locus": { "chromosome": "1", "start_pos": 176156444, "end_pos": 176162167, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005785", "url": "https://www.ensembl.org/id/ENSGALG00010005785" } ] } } ], "crossref": [ { "id": "R4GIQ2", "url": "https://alphafold.ebi.ac.uk/entry/R4GIQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027035", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418933", "url": "https://www.ncbi.nlm.nih.gov/gene/418933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418933", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INYGDYV", "url": "https://omabrowser.org/oma/group/INYGDYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GIQ2", "url": "https://www.orthodb.org/?gene=R4GIQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01157", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01157", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", 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"MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQQGMPHKCYHGKTGRVYNVTQHAVGVIVNKKVKGKILAKRINVRIEHIKHSKSRDSFLQRVKENEKKKKEAKEKGIWVQLKRQPAPPREAHFVRTNGKDPELLEPIPYEFMA", "length": 160, "header": "tr|R4GIQ2-1|R4GIQ2_CHICK Isoform 1 of Large ribosomal subunit protein eL21 OS=Gallus gallus OX=9031 GN=RPL21 PE=1 SV=1 CANONICAL=R4GIQ2-1" }, "isoforms": [ { "isoform_ac": "R4GIQ2-1", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2/entry#R4GIQ2-1", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQQGMPHKCYHGKTGRVYNVTQHAVGVIVNKKVKGKILAKRINVRIEHIKHSKSRDSFLQRVKENEKKKKEAKEKGIWVQLKRQPAPPREAHFVRTNGKDPELLEPIPYEFMA", "length": 160, "header": "tr|R4GIQ2-1|R4GIQ2_CHICK Isoform 1 of Large ribosomal subunit protein eL21 OS=Gallus gallus OX=9031 GN=RPL21 PE=1 SV=1 CANONICAL=R4GIQ2-1" }, "locus": { "chromosome": "1", "start_pos": 176161186, "end_pos": 176157715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013789.1", "url": "https://www.ensembl.org/id/ENSGALT00010013789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008160.1", "url": "https://www.ensembl.org/id/ENSGALP00010008160.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:418933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418933", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QEI2-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O09167-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P46778-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "RPL21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49666-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "RPL21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q02753-1", "protein_name": "Large ribosomal subunit protein eL21A", "gene_name": "RPL21A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54X53-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "rpl21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPHSFGLRARTRYLFSRGFRNHGLLQTTTFLRTFRLGDYVDIKATGNVHKGMPHKFYHGRTGRVWNVTPRAVGVIINKRVGPRIIAKKIHVRTEHVKPSNSMAAHLKRIQENKKAVVEAKKAGKWVDVRRNPAAPKDGFFVNPRNTEFVEVKPVKYELLL", "length": 160 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FDZ9-1", "protein_name": "Large ribosomal subunit protein eL21x/eL21w", "gene_name": "RPL21E", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPAGHGVRARTRDLFARPFRKKGYIPLSTYLRTFKVGDYVDVKVNGAIHKGMPHKFYHGRTGRIWNVTKRAVGVEVNKQIGNRIIRKRIHVRVEHVQQSRCAEEFKLRKKQNDVLKADAKARGETISTKRQPKGPKPGFMVEGMTLETVTPIPYDVVNDLKGGY", "length": 164 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V9M7-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "RpL21", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTNSKGYRRGTRDMFSRPFRKHGVIPLSTYMRVFKIGDIVDIKGHGAVQKGLPYKAYHGKTGRIFNVTQHAVGVIVNKRVRGKILAKRVNVRIEHIHHSKCREDFLRRVKENERLLKEAKEKGQWVSLKRQPEQPKKAHFVKKLEEPIALAPIPYEFIA", "length": 159 }, "evidence": [ { "id": "R4GIQ2", "url": "https://omabrowser.org/oma/group/R4GIQ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "R4GIQ2", "url": "https://www.uniprot.org/uniprotkb/R4GIQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GIQ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 160, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GIQ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GIQ2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "R4GIT0-1", "uniprot_ac": "R4GIT0", "uniprot_id": "R4GIT0_CHICK", "mass": { "chemical_mass": 20041.0, "monoisotopic_mass": 20041.0 }, "refseq": { "ac": "XP_416786", "name": "transmembrane protein 47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416786" }, "gene_names": [ { "name": "TMEM47", "type": "recommended", "evidence": [ { "id": "R4GIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT0" } ] }, { "name": "TMEM47", "type": "synonym", "evidence": [ { "id": "XP_416786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416786" } ] } ], "protein_names": [ { "name": "Transmembrane protein 47", "type": "recommended", "evidence": [ { "id": "R4GIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT0/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane 4 superfamily member 10", "type": "synonym", "evidence": [ { "id": "R4GIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIT0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 47", "type": "synonym", "evidence": [ { "id": "XP_416786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416786" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416786" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GIT0", "url": "https://www.uniprot.org/uniprotkb/R4GIT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM47", "url": "https://www.uniprot.org/uniprotkb/R4GIT0", "locus": { "chromosome": "1", "start_pos": 114058712, "end_pos": 114031879, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002335", "url": "https://www.ensembl.org/id/ENSGALG00010002335" } ] } } ], "crossref": [ { "id": "R4GIT0", "url": "https://alphafold.ebi.ac.uk/entry/R4GIT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027198", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418585", "url": "https://www.ncbi.nlm.nih.gov/gene/418585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418585", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418585", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVETATM", "url": "https://omabrowser.org/oma/group/FVETATM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GIT0", "url": "https://www.orthodb.org/?gene=R4GIT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14399:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14399:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GIT0", "url": "https://www.uniprot.org/uniprotkb/R4GIT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GIT0-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPGNLESWLCESTLHSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181, "header": "tr|R4GIT0-1|R4GIT0_CHICK Isoform 1 of Transmembrane protein 47 OS=Gallus gallus OX=9031 GN=TMEM47 PE=3 SV=1 CANONICAL=R4GIT0-1" }, "isoforms": [ { "isoform_ac": "R4GIT0-1", "url": "https://www.uniprot.org/uniprotkb/R4GIT0/entry#R4GIT0-1", "sequence": { "sequence": "MASSGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPGNLESWLCESTLHSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181, "header": "tr|R4GIT0-1|R4GIT0_CHICK Isoform 1 of Transmembrane protein 47 OS=Gallus gallus OX=9031 GN=TMEM47 PE=3 SV=1 CANONICAL=R4GIT0-1" }, "locus": { "chromosome": "1", "start_pos": 114055093, "end_pos": 114032110, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005282.1", "url": "https://www.ensembl.org/id/ENSGALT00010005282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003121.1", "url": "https://www.ensembl.org/id/ENSGALP00010003121.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418585", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418585", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LHK8-1", "protein_name": "Transmembrane protein 47", "gene_name": "CG6982", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHQQYQQQQQQQQQGNLVGYNNKMNVLPNYTLSGMSSFDAESLPDYSEFDSESVTLDYYKESVLRPPAEKMAPTTTIETITITRPLKVIAFICGVIVVALMIMALASTDWLMASDWRQGLFVHCIEDDSVPPLPFNIQDPPGCYWTRDVGYIKATAALCIITLITDVIATVLTGLGLRTQNHNLKYKFYRIAVLVMLVSLLAVLSALIVYPVCFAGELTMANRRVWEFGWAYGVGWGAAIFLFGAVVLLLCDKESEEIYYKERKIVHENQMRA", "length": 273 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZBB3-1", "protein_name": "Transmembrane protein 47", "gene_name": "Tmem47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPANLDSWHCESTLGSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F2Z5B3-1", "protein_name": "Transmembrane protein 47", "gene_name": "TMEM47", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1JPA3-1", "protein_name": "Transmembrane protein 47", "gene_name": "TMEM47", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PFT6-1", "protein_name": "Transmembrane protein 47", "gene_name": "tmem47", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSVSGAEEVRVSALTPLKLVGLVCVFLALCLDVGAVLSPAWVTADDQYHLSLWKSCSKPAASATWRCNSTLGTDWQIATLALLLGGAFLILLSFLVALVSVCIRSRRRFYRPVAIMLFAAVVLQACCLVLYPIKFIETISLRIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BQJ4-1", "protein_name": "Transmembrane protein 47", "gene_name": "TMEM47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJG6-1", "protein_name": "Transmembrane protein 47", "gene_name": "Tmem47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRKPANLDIWHCESTLGSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY", "length": 181 }, "evidence": [ { "id": "R4GIT0", "url": "https://omabrowser.org/oma/group/R4GIT0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GIT0", "url": "https://www.uniprot.org/uniprotkb/R4GIT0" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "R4GIT0", 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"https://data.glygen.org/ln2downloads/pdb/current/AF-R4GIT0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GIT0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJC4-1", "uniprot_ac": "R4GJC4", "uniprot_id": "R4GJC4_CHICK", "mass": { "chemical_mass": 24705.0, "monoisotopic_mass": 24705.0 }, "refseq": {}, "gene_names": [ { "name": "CMPK2", "type": "recommended", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ] } ], "protein_names": [ { "name": "UMP-CMP kinase 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.14", "type": "synonym", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.9", "type": "synonym", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4/entry#names_and_taxonomy" } ] }, { "name": "Nucleoside-diphosphate kinase", "type": "synonym", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CMPK2", "url": "https://www.uniprot.org/uniprotkb/R4GJC4", "locus": { "chromosome": "3", "start_pos": 94664883, "end_pos": 94671910, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002380", "url": "https://www.ensembl.org/id/ENSGALG00010002380" } ] } } ], "crossref": [ { "id": "R4GJC4", "url": "https://alphafold.ebi.ac.uk/entry/R4GJC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028982", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028982", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR014505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "R4GJC4", "url": "https://www.orthodb.org/?gene=R4GJC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10344:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10344:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11600", "url": "https://www.rhea-db.org/rhea/11600", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "13517", "url": "https://www.rhea-db.org/rhea/13517", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18113", "url": "https://www.rhea-db.org/rhea/18113", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25094", "url": "https://www.rhea-db.org/rhea/25094", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJC4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ARIPEAGSVLDILEKCPEGQRKGEFPVVVFEGLDATGKTTVTQSVKDALGAVLLRSPPACISQWRTIFDEEPTPIRRAFYAAGNYILASEIAKASTQAPVIVDRYWHSTAAYTVATETDGNIQNLPPDHDAVYKWPEDLLKPDLVLLLTVSPEERARRLEARGLERTKEEAELEANSLFRQRIEESYRRMVNPACQEVDASPSKEEVFKTVLQLIKKHCAL", "length": 221, "header": "tr|R4GJC4-1|R4GJC4_CHICK Isoform 1 of UMP-CMP kinase 2, mitochondrial OS=Gallus gallus OX=9031 GN=CMPK2 PE=1 SV=3 CANONICAL=R4GJC4-1" }, "isoforms": [ { "isoform_ac": "R4GJC4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJC4/entry#R4GJC4-1", "sequence": { "sequence": "ARIPEAGSVLDILEKCPEGQRKGEFPVVVFEGLDATGKTTVTQSVKDALGAVLLRSPPACISQWRTIFDEEPTPIRRAFYAAGNYILASEIAKASTQAPVIVDRYWHSTAAYTVATETDGNIQNLPPDHDAVYKWPEDLLKPDLVLLLTVSPEERARRLEARGLERTKEEAELEANSLFRQRIEESYRRMVNPACQEVDASPSKEEVFKTVLQLIKKHCAL", "length": 221, "header": "tr|R4GJC4-1|R4GJC4_CHICK Isoform 1 of UMP-CMP kinase 2, mitochondrial OS=Gallus gallus OX=9031 GN=CMPK2 PE=1 SV=3 CANONICAL=R4GJC4-1" }, "locus": { "chromosome": "3", "start_pos": 94671703, "end_pos": 94667184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005448.1", "url": "https://www.ensembl.org/id/ENSGALT00010005448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003287.1", "url": "https://www.ensembl.org/id/ENSGALP00010003287.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "dTMP kinase activity", "id": "GO:0004798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004798", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "dTDP biosynthetic process", "id": "GO:0006233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006233", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "dUDP biosynthetic process", "id": "GO:0006227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006227", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" }, { "name": "dTTP biosynthetic process", "id": "GO:0006235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006235", "evidence": [ { "database": "UniProtKB", "id": "R4GJC4", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11600", "name": "", "equation": "CMP + ATP = CDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZKE7-1", "A0A8V0ZQU1-1", "R4GJC4-1" ], "evidence": [ { "id": "11600", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11600" } ] }, { "id": "13517", "name": "", "equation": "dTMP + ATP = dTDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GJC4-1", "A0A1D5PKC2-1" ], "evidence": [ { "id": "13517", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13517" } ] }, { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O57535-1", "A0A8V0ZQU1-1", "A0A8V0Z6S4-1", "Q5ZKE7-1", "P05081-1", "A0A8V0ZN35-1", "A0A8V0XUT9-1", "R4GJC4-1" ], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "25094", "name": "", "equation": "dCMP + ATP = dCDP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZKE7-1", "A0A8V0ZQU1-1", "R4GJC4-1" ], "evidence": [ { "id": "25094", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25094" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O57535-1", "A0A8V0ZQU1-1", "A0A8V1AL38-1", "A0A8V0XUT9-1", "A0A8V0Z6S4-1", "Q5ZKE7-1", "P05081-1", "A0A8V0ZN35-1", "R4GJC4-1" ], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PKC2", "gene_name": "DTYMK", "activity": [ { "ec_number": "2.7.4.9", "activity": "dTMP + ATP = dTDP + ADP.", "evidence": [ { "id": 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all introns SAMEA103992323, SAMEA103992639 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ851772.1, AM067925.1 and JAENSK010000035.1. On Sep 7, 2012 this sequence version replaced XP_003640697.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001258101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258101" } ] }, { "annotation": "CAMP and CATHB1 were significantly up-regulated in bone marrow cells, whereas the expression of CATH3 did not differ significantly between chicken bone marrow cells and chicken embryonic fibroblasts.", "evidence": [ { "database": "RefSeq", "id": "NP_001258101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258101" }, { "database": "PubMed", "id": "26908883", "url": "https://glygen.org/publication/PubMed/26908883" } ] }, { "annotation": "The immunomodulatory effect of cathelicidin-B1 on chicken macrophages. 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GJF1", "url": "https://www.uniprot.org/uniprotkb/R4GJF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJF1-1", "url": "https://www.uniprot.org/uniprotkb/R4GJF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRMWASEVLLLLLLGSSRAVTPGLDVSTAPGLDGSIPPGLDGSIPPGLDGSVSPGLDGSVSPGLDGSVSPGLDGSASPGLDGSTPAGRDGTITPKLEGTITPKQDGSISPSWPWRWPITYLDAILAAVRLLNQRISGPCILRLREAQPRPGWVGTLQRRREVSFLVEDGPCPPGVDCRSCEPGALQHCVGTVSIEQQPTAELRCRPLRPQPIRNWWIRIWEWLNGIRKRLRQRSPFYVRGHLNVTSTPQP", "length": 251, "header": "tr|R4GJF1-1|R4GJF1_CHICK Isoform 1 of Cathelicidin B1 OS=Gallus gallus OX=9031 GN=CATHB1 PE=3 SV=1 CANONICAL=R4GJF1-1" }, "isoforms": [ { "isoform_ac": "R4GJF1-1", "url": "https://www.uniprot.org/uniprotkb/R4GJF1/entry#R4GJF1-1", "sequence": { "sequence": 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true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Transcriptional regulation of cathelicidin genes in chicken bone marrow cells.", "journal": "Poultry science", "date": "2016-04", "authors": "Lee Sang In, Jang Hyun June, Jeon Mi-hyang, Lee Mi Ock, Kim Jeom Sun, Jeon Ik-Soo, Byun Sung June", "evidence": [ { "database": "RefSeq", "id": "NP_001258101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258101" } ], "reference": [ { "type": "PubMed", "id": "26908883", "url": "https://glygen.org/publication/PubMed/26908883" } ] }, { "title": "The immunomodulatory effect of cathelicidin-B1 on chicken macrophages.", "journal": "Veterinary research", "date": "2020-09-24", "authors": "Peng Lianci, Scheenstra Maaike R, van Harten Roel M, Haagsman Henk P, Veldhuizen Edwin J A", "evidence": [ { "database": "RefSeq", "id": "NP_001258101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258101" } ], "reference": [ { "type": "PubMed", "id": "32972448", "url": "https://glygen.org/publication/PubMed/32972448" } ] } ], "pathway": [ { "id": "gga:100858412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858412", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ 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annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940351" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HS3ST5", "url": "https://www.uniprot.org/uniprotkb/R4GJI3", "locus": { "chromosome": "3", "start_pos": 64466333, "end_pos": 64371755, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013363", "url": "https://www.ensembl.org/id/ENSGALG00010013363" } ] } } ], "crossref": [ { "id": "R4GJI3", "url": "https://alphafold.ebi.ac.uk/entry/R4GJI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026594", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428621", "url": "https://www.ncbi.nlm.nih.gov/gene/428621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428621", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISLYHTY", "url": "https://omabrowser.org/oma/group/ISLYHTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GJI3", "url": "https://www.orthodb.org/?gene=R4GJI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004940351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940351", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15461", "url": 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{ "sequence": "MLFKQQVLLRQKLFVLGSLAIGSLLYLVARVGSLDRLQPLCPIDGRFGPRSQDEIPLRALQFKRGLLHEFRKGNATKEQIRLHNLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGTEWYRKKMPFSYPHQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIVFNKCLAGSKGRIHPEVDTSVITKLRKFFHPFNQKFYQITGRTFNWP", "length": 345, "header": "tr|R4GJI3-1|R4GJI3_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=HS3ST5 PE=3 SV=1 CANONICAL=R4GJI3-1" }, "locus": { "chromosome": "3", "start_pos": 64465523, "end_pos": 64460238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032167.1", "url": "https://www.ensembl.org/id/ENSGALT00010032167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018957.1", "url": "https://www.ensembl.org/id/ENSGALP00010018957.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:428621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428621", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I575-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLALGSLLYLVARVGSLDRLQPICPVESRFGGTHSQAEFPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "R4GJI3", "url": "https://omabrowser.org/oma/group/R4GJI3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZDL1-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGAAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLMIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "R4GJI3", "url": "https://omabrowser.org/oma/group/R4GJI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZK7-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLFKQQAWLRQKLLVLGSLAIGSLLYLVARVGSLDRLQPLCPIEGRFGAHGQAEFPLRALQFKRGLLHEFRKGNASKEHVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYRMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLIAEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKFFHPFNQKFYQITGRTLNWP", "length": 345 }, "evidence": [ { "id": "R4GJI3", "url": "https://omabrowser.org/oma/group/R4GJI3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BSL4-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 5", "gene_name": "Hs3st5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGGAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVHLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "R4GJI3", "url": "https://omabrowser.org/oma/group/R4GJI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZT8-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 5", "gene_name": "HS3ST5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLFKQQAWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLLHEFRKGNASKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP", "length": 346 }, "evidence": [ { "id": "R4GJI3", "url": "https://omabrowser.org/oma/group/R4GJI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of viral entry into host cell", "id": "GO:0046596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046596", "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "pmid": "" }, { "name": "negative regulation of coagulation", "id": "GO:0050819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050819", "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "R4GJI3", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15461", "name": "", "equation": "alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BY16-1", "E1C4I5-1", "R4GJI3-1" ], "evidence": [ { "id": "15461", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15461" } ] }, { "id": "R-GGA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AQB3-1", "F1NL56-1", "F1NW51-1", "A0A8V0Z1U8-1", "A0A8V0ZEP2-1", "R4GJI3-1" ], "evidence": [ { "id": "R-GGA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z1U8", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0Z1U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1U8" } ] } ] }, { "uniprot_ac": "A0A8V0ZEP2", "gene_name": "HS3ST6", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP2" } ] } ] }, { "uniprot_ac": "A0A8V1AQB3", "gene_name": "HS3ST3B1L", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V1AQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQB3" } ] } ] }, { "uniprot_ac": "E1BY16", "gene_name": "LOC423822", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BY16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY16" } ] } ] }, { "uniprot_ac": "E1C4I5", "gene_name": "HS3ST1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1C4I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4I5" } ] } ] }, { "uniprot_ac": "F1NL56", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ] } ] }, { "uniprot_ac": "F1NW51", "gene_name": "HS3ST4", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ] } ] }, { "uniprot_ac": "R4GJI3", "gene_name": "HS3ST5", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "R4GJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GJI3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 345, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GJI3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GJI3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 334, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJK4-1", "uniprot_ac": "R4GJK4", "uniprot_id": "R4GJK4_CHICK", "mass": { "chemical_mass": 21217.0, "monoisotopic_mass": 21217.0 }, "refseq": { "ac": "NP_001264404", "name": "translocon-associated protein subunit gamma", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" }, "gene_names": [ { "name": "SSR3", "type": "recommended", "evidence": [ { "id": "R4GJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJK4" } ] }, { "name": "SSR3", "type": "synonym", "evidence": [ { "id": "NP_001264404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" } ] } ], "protein_names": [ { "name": "Translocon-associated protein subunit gamma", "type": "recommended", "evidence": [ { "id": "R4GJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJK4/entry#names_and_taxonomy" } ] }, { "name": "Signal sequence receptor subunit gamma", "type": "synonym", "evidence": [ { "id": "R4GJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJK4/entry#names_and_taxonomy" } ] }, { "name": "signal sequence receptor gamma subunit", "type": "synonym", "evidence": [ { "id": "NP_001264404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" } ] }, { "name": "signal sequence receptor, gamma (translocon-associated protein gamma)", "type": "synonym", "evidence": [ { "id": "NP_001264404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" } ] }, { "name": "translocon-associated protein subunit gamma", "type": "synonym", "evidence": [ { "id": "NP_001264404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934097.1, BX935792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU322139.1 and BX934097.1. On Apr 10, 2013 this sequence version replaced XP_422829.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404" } ] }, { "annotation": "TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.", "evidence": [ { "database": "UniProtKB", "id": "R4GJK4", "url": "https://www.uniprot.org/uniprotkb/R4GJK4#function" }, { "database": "UniProtKB", "id": "ARBA00002838", "url": "https://www.uniprot.org/uniprotkb/ARBA00002838#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJK4", "url": "https://www.uniprot.org/uniprotkb/R4GJK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSR3", "url": "https://www.uniprot.org/uniprotkb/R4GJK4", "locus": { "chromosome": "9", "start_pos": 22597694, "end_pos": 22591278, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001505", "url": "https://www.ensembl.org/id/ENSGALG00010001505" } ] } } ], "crossref": [ { "id": "R4GJK4", "url": "https://alphafold.ebi.ac.uk/entry/R4GJK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028683", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028683", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425027", "url": "https://www.ncbi.nlm.nih.gov/gene/425027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425027", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425027", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLWLFWR", "url": "https://omabrowser.org/oma/group/PLWLFWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GJK4", "url": "https://www.orthodb.org/?gene=R4GJK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13399:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13399:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264404", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GJK4", "url": "https://www.uniprot.org/uniprotkb/R4GJK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJK4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKGGPGGRQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLVQSAVLYSVMTLISTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIIASFFVLKNFNPTVNYILSISASSGLIALLSTGSK", "length": 187, "header": "tr|R4GJK4-1|R4GJK4_CHICK Isoform 1 of Translocon-associated protein subunit gamma OS=Gallus gallus OX=9031 GN=SSR3 PE=1 SV=1 CANONICAL=R4GJK4-1" }, "isoforms": [ { "isoform_ac": "R4GJK4-1", "url": "https://www.uniprot.org/uniprotkb/R4GJK4/entry#R4GJK4-1", "sequence": { "sequence": "MAPKGGPGGRQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLVQSAVLYSVMTLISTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIIASFFVLKNFNPTVNYILSISASSGLIALLSTGSK", "length": 187, "header": "tr|R4GJK4-1|R4GJK4_CHICK Isoform 1 of Translocon-associated protein subunit gamma OS=Gallus gallus OX=9031 GN=SSR3 PE=1 SV=1 CANONICAL=R4GJK4-1" }, "locus": { "chromosome": "9", "start_pos": 22594677, "end_pos": 22591307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003475.1", "url": "https://www.ensembl.org/id/ENSGALT00010003475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001917.1", "url": "https://www.ensembl.org/id/ENSGALP00010001917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425027", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LGD6-1", "protein_name": "Translocon-associated protein subunit gamma", "gene_name": "SSR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPKGGSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK", "length": 185 }, "evidence": [ { "id": "R4GJK4", "url": "https://omabrowser.org/oma/group/R4GJK4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3SZ87-1", "protein_name": "Translocon-associated protein subunit gamma", "gene_name": "SSR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKGGPKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK", "length": 185 }, "evidence": [ { "id": "R4GJK4", "url": "https://omabrowser.org/oma/group/R4GJK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55GT5-1", "protein_name": "Translocon-associated protein subunit gamma", "gene_name": "ssr3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAEVDEFSAFRHENDVSIEQRIVYFINSLIVALVPVYLYHAIFFMSIDDHMIIYGSVTLFAAIVLTFAYNNIYRMKRLKLSASREHISIASKNKVGDKKKFAAAQKEVQALVTSHEAIAASIMYNNAVFLICVSIFSFIIFKNVPLVYNYIISISLGAGLTSFLSTSSKH", "length": 170 }, "evidence": [ { "id": "R4GJK4", "url": "https://omabrowser.org/oma/group/R4GJK4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DCF9-1", "protein_name": "Translocon-associated protein subunit gamma", "gene_name": "Ssr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKGGSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK", "length": 185 }, "evidence": [ { "id": "R4GJK4", "url": "https://omabrowser.org/oma/group/R4GJK4/", "database": "OMA" } ], 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} ], "function": [ { "annotation": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. 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"tr|R4GJP9-1|R4GJP9_CHICK Isoform 1 of Histone H2A OS=Gallus gallus OX=9031 GN=H2A2BL PE=1 SV=2 CANONICAL=R4GJP9-1" }, "locus": { "chromosome": "12", "start_pos": 9307731, "end_pos": 9307354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066146.1", "url": "https://www.ensembl.org/id/ENSGALT00010066146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040412.1", "url": "https://www.ensembl.org/id/ENSGALP00010040412.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101751709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751709", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AA54CQH7-1", "protein_name": "Histone H2A", "gene_name": "si:ch211-113a14.25", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAESYAIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 215 }, "evidence": [ { "id": "R4GJP9", "url": "https://omabrowser.org/oma/group/R4GJP9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O04848-1", "protein_name": "Probable histone H2AXa", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTGAGSGTTKGGRGKPKATKSVSRSSKAGLQFPVGRIARFLKSGKYAERVGAGAPVYLSAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSKLLGSVTIANGGVLPNIHQTLLPSKVGKNKGDIGSASQEF", "length": 142 }, "evidence": [ { "id": "R4GJP9", "url": "https://omabrowser.org/oma/group/R4GJP9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY", "length": 143 }, "evidence": [ { "id": "R4GJP9", "url": "https://omabrowser.org/oma/group/R4GJP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P27661-1", "protein_name": "Histone H2AX", "gene_name": "H2ax", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSATVGPKAPAVGKKASQASQEY", "length": 143 }, "evidence": [ { "id": "R4GJP9", "url": "https://omabrowser.org/oma/group/R4GJP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4AB57-1", 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The reference sequence was derived from JAENSK010000252.1. On Apr 26, 2013 this sequence version replaced XP_414328.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. 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motif 2", "type": "synonym", "evidence": [ { "id": "R4GJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJX0/entry#names_and_taxonomy" } ] }, { "name": "bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "type": "synonym", "evidence": [ { "id": "XP_424973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424973" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424973" } ] }, { "annotation": "Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP. Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro.", "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0#function" }, { "database": "UniProtKB", "id": "ARBA00045172", "url": "https://www.uniprot.org/uniprotkb/ARBA00045172#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUDT2", "url": "https://www.uniprot.org/uniprotkb/R4GJX0", "locus": { "chromosome": "Z", "start_pos": 8156026, "end_pos": 8150443, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011911", "url": "https://www.ensembl.org/id/ENSGALG00010011911" } ] } } ], "crossref": [ { "id": "R4GJX0", "url": "https://alphafold.ebi.ac.uk/entry/R4GJX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027295", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027295", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427399", "url": "https://www.ncbi.nlm.nih.gov/gene/427399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427399", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRDYEQA", "url": "https://omabrowser.org/oma/group/WRDYEQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GJX0", "url": "https://www.orthodb.org/?gene=R4GJX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21340:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21340:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22484", "url": "https://www.rhea-db.org/rhea/22484", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67588", "url": "https://www.rhea-db.org/rhea/67588", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67592", "url": "https://www.rhea-db.org/rhea/67592", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJX0-1", "url": "https://www.uniprot.org/uniprotkb/R4GJX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRACGLIIYRRLQSSPSSKAADSIEYLLLQTSYGTHHWTPPKGHVDPGEDDLQTAFRETQEEAGLQASQLNLVEGYRKELHYPVHGKPKTVVYWLAEVKDCNTEIKLSEEHQAFRWLKLEDACKFAEYEDMQATLKDAHQFLSSNK", "length": 148, "header": "tr|R4GJX0-1|R4GJX0_CHICK Isoform 1 of Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Gallus gallus OX=9031 GN=NUDT2 PE=1 SV=2 CANONICAL=R4GJX0-1" }, "isoforms": [ { "isoform_ac": "R4GJX0-1", "url": "https://www.uniprot.org/uniprotkb/R4GJX0/entry#R4GJX0-1", "sequence": { "sequence": "MAVRACGLIIYRRLQSSPSSKAADSIEYLLLQTSYGTHHWTPPKGHVDPGEDDLQTAFRETQEEAGLQASQLNLVEGYRKELHYPVHGKPKTVVYWLAEVKDCNTEIKLSEEHQAFRWLKLEDACKFAEYEDMQATLKDAHQFLSSNK", "length": 148, "header": "tr|R4GJX0-1|R4GJX0_CHICK Isoform 1 of Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Gallus gallus OX=9031 GN=NUDT2 PE=1 SV=2 CANONICAL=R4GJX0-1" }, "locus": { "chromosome": "Z", "start_pos": 8155045, "end_pos": 8151631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028483.1", "url": "https://www.ensembl.org/id/ENSGALT00010028483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016343.1", "url": "https://www.ensembl.org/id/ENSGALP00010016343.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427399", "resource": "KEGG Pathway" }, { "id": "R-GGA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" } ], "orthologs": [ { "uniprot_canonical_ac": "P50583-1", "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "NUDT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA", "length": 147 }, "evidence": [ { "id": "R4GJX0", "url": "https://omabrowser.org/oma/group/R4GJX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50584-1", "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "NUDT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRACGLIIFRRRLIPKVDNTAIEFLLLQASNGIHHWTPPKGHVEPGESDLQTALRETQEEAGIDAGQLTIIEGFRKELNYVAWEKPKTVIYWLAEVKDYDVEVRLSREHQAYRWLGLDEACQLAQFKDMKAVLQEGHQFLCSMAA", "length": 147 }, "evidence": [ { "id": "R4GJX0", "url": "https://omabrowser.org/oma/group/R4GJX0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P56380-1", "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "Nudt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRACGLIIFRRHLIPKMDNSTIEFLLLQASDGIHHWTPPKGHVDPGENDLETALRETREETGIEASQLTIIEGFRRELNYVARQKPKTVIYWLAEVKDYNVEIRLSQEHQAYRWLGLEEACQLAQFKEMKATLQEGHQFLCSTPA", "length": 147 }, "evidence": [ { "id": "R4GJX0", "url": "https://omabrowser.org/oma/group/R4GJX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q29RJ1-1", "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "NUDT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALRACGLIIFRRRLIPKVDNTAIEFLLLQASDGIHHWTPPKGHVEPGESDLETALRETQEEAGIEAGQLTIIEGFRRELSYVARAKPKIVIYWLAEVKDCDVEVRLSREHQAYRWLELEDACQLAQFEEMKAALQEGHQFLCSTAT", "length": 147 }, "evidence": [ { "id": "R4GJX0", "url": "https://omabrowser.org/oma/group/R4GJX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PEC0-1", "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "Nudt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRACGLIIFRRHLIPKVDNTTIEFLLLQASDGIHHWTPPKGHVDPGENDLETALRETQEETGIEASQLIVLEGFRRELNYVARKKPKTVIYWLAEVKDYDVEIRLSQEHQAYRWLGLDEACQLAQFEEMKATLQEGHQFLCSTPA", "length": 147 }, "evidence": [ { "id": "R4GJX0", "url": "https://omabrowser.org/oma/group/R4GJX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ], "pmid": "" }, { "name": "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity", "id": "GO:0004081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004081", "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ATP biosynthetic process", "id": "GO:0006754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006754", "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ], "pmid": "" }, { "name": "AMP biosynthetic process", "id": "GO:0006167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006167", "evidence": [ { "database": "UniProtKB", "id": "R4GJX0", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22484", "name": "", "equation": "P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GMP + GTP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GJX0-1", "A0A8V0XRJ3-1" ], "evidence": [ { "id": "22484", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22484" } ] }, { "id": "67588", "name": "", "equation": "a 5'-end FAD-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + FMN + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GJX0-1" ], "evidence": [ { "id": "67588", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67588" } ] }, { "id": "67592", "name": "", "equation": "a 5'-end CoA-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + (R)-4'-phosphopantetheine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "R4GJX0-1", "Q5ZL13-1", "A0A8V0Y1Q3-1", "A0A8V0XEZ2-1" ], "evidence": [ { "id": "67592", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67592" } ] }, { "id": "R-GGA-5696197", "name": "NUDT2 hydrolyses GP4G to GTP, GMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-5696199" ], "output_participant_list": [ "R-ALL-5696194" ], "enzyme_list": [ "R4GJX0-1" ], "evidence": [ { "id": "R-GGA-5696197", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696197" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5696194", "participant_name": "GMP [mitochondrial matrix]", "crossref": [ { "id": "ZINC000002159505", "database": "ZINC", "url": "" }, { "id": "C00144", "database": "COMPOUND", "url": "" }, { "id": "58115", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5696199", "participant_name": "GP4G [mitochondrial matrix]", "crossref": [ { "id": "15883", "database": "ChEBI", "url": "" }, { "id": "C01261", "database": "COMPOUND", "url": "" }, { "id": "ZINC000096014516", "database": "ZINC", "url": "" }, { "id": "HMDB0001340", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XEZ2", "gene_name": "NUDT15", "activity": [ { "ec_number": "3.6.1.9", "activity": "dTTP + H2O = dTMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] }, { "ec_number": "3.6.1.68", "activity": "(2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] }, { "ec_number": "3.6.1.76", "activity": "dimethylallyl diphosphate + H2O = dimethylallyl phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] }, { "ec_number": "3.6.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] }, { "ec_number": "3.6.1.76", "activity": "", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] }, { "ec_number": "3.6.1.68", "activity": "", "evidence": [ { "id": "A0A8V0XEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ2" } ] } ] }, { "uniprot_ac": "A0A8V0XRJ3", "gene_name": "ENPP3", "activity": [ { "ec_number": "3.1.4.1", "activity": "Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.", "evidence": [ { "id": "A0A8V0XRJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRJ3" } ] }, { "ec_number": "3.6.1.9", "activity": "dTTP + H2O = dTMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8V0XRJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRJ3" } ] }, { "ec_number": "3.1.4.1", "activity": "", "evidence": [ { "id": "A0A8V0XRJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRJ3" } ] }, { "ec_number": "3.6.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XRJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRJ3" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] } ] }, { "uniprot_ac": "R4GJX0", "gene_name": "NUDT2", "activity": [ { "ec_number": "3.6.1.17", "activity": "P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GMP + GTP + 2 H(+).", "evidence": [ { "id": "R4GJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ] }, { "ec_number": "3.6.1.17", "activity": "", "evidence": [ { "id": "R4GJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJX0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GJX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 148, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GJX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GJX0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.17", "ec_name": "P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GMP + GTP + 2 H(+).", "evidence": [ { "id": "3.6.1.17", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.17" }, { "id": "3.6.1.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.17" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GJZ6-1", "uniprot_ac": "R4GJZ6", "uniprot_id": "R4GJZ6_CHICK", "mass": { "chemical_mass": 33339.0, "monoisotopic_mass": 33339.0 }, "refseq": { "ac": "XP_424995", "name": "Golgi phosphoprotein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424995" }, "gene_names": [ { "name": "GOLPH3", "type": "recommended", "evidence": [ { "id": "R4GJZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ] }, { "name": "GOLPH3", "type": "synonym", "evidence": [ { "id": "XP_424995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424995" } ] } ], "protein_names": [ { "name": "Golgi phosphoprotein 3", "type": "synonym", "evidence": [ { "id": "XP_424995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424995" }, { "id": "R4GJZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_424995.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424995" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLPH3", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6", "locus": {} } ], "crossref": [ { "id": "R4GJZ6", "url": "https://alphafold.ebi.ac.uk/entry/R4GJZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028267", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028267", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427422", "url": "https://www.ncbi.nlm.nih.gov/gene/427422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GETWNLL", "url": "https://omabrowser.org/oma/group/GETWNLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GJZ6", "url": "https://www.orthodb.org/?gene=R4GJZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12704:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12704:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424995", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJZ6-1", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLTQRSSGLVQRRTEASRSAAADKERGAGGGSEDEGRREEPGDDEKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHIKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDKRLLALVYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECMKANTNEVLWAVVAAFTK", "length": 294, "header": "tr|R4GJZ6-1|R4GJZ6_CHICK Isoform 1 of Golgi phosphoprotein 3 OS=Gallus gallus OX=9031 GN=GOLPH3 PE=1 SV=1 CANONICAL=R4GJZ6-1" }, "isoforms": [ { "isoform_ac": "R4GJZ6-1", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6/entry#R4GJZ6-1", "sequence": { "sequence": "MTSLTQRSSGLVQRRTEASRSAAADKERGAGGGSEDEGRREEPGDDEKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHIKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDKRLLALVYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECMKANTNEVLWAVVAAFTK", "length": 294, "header": "tr|R4GJZ6-1|R4GJZ6_CHICK Isoform 1 of Golgi phosphoprotein 3 OS=Gallus gallus OX=9031 GN=GOLPH3 PE=1 SV=1 CANONICAL=R4GJZ6-1" }, "locus": { "chromosome": "Z", "start_pos": 10249873, "end_pos": 10221320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035792.1", "url": "https://www.ensembl.org/id/ENSGALT00010035792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020754.1", "url": "https://www.ensembl.org/id/ENSGALP00010020754.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q06385-1", "protein_name": "Vacuolar protein sorting-associated protein 74", "gene_name": "VPS74", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTLQRRRVNRADSGDTSSIHSSANNTKGDKIANIAVDGDDDNGTNKKIAYDPEESKLRDNINIPTLTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFDLSERLIEVIDSSKTGEVLLDETLQLMKNDEPLSISNWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPIADASCKEAIKRRVLSVLVSRNMELSYNEYFPETTSFKIIRTLALICGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKETELGVSVNLNKEVKEEIENNPGHDLQLEVIAGVFEVFSRMDMLL", "length": 345 }, "evidence": [ { "id": "R4GJZ6", "url": "https://omabrowser.org/oma/group/R4GJZ6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9CRA5-1", "protein_name": "Golgi phosphoprotein 3", "gene_name": "Golph3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLTQRSSGLVQRRTEASRNAADKERAAGGGGGSGEDEAQSRRDEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECLKANTNEVLWAVVAAFTK", "length": 298 }, "evidence": [ { "id": "R4GJZ6", "url": "https://omabrowser.org/oma/group/R4GJZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ERE4-1", "protein_name": "Golgi phosphoprotein 3", "gene_name": "Golph3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLTQRSSGLVQRRTEASRNAADKERAAGGGGGNGEDEAQSRRDEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECLKANTNEVLWAVVAAFTK", "length": 298 }, "evidence": [ { "id": "R4GJZ6", "url": "https://omabrowser.org/oma/group/R4GJZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H4A6-1", "protein_name": "Golgi phosphoprotein 3", "gene_name": "GOLPH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSLTQRSSGLVQRRTEASRNAADKERAAGGGAGSSEDDAQSRRDEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDRRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECLKANTNEVLWAVVAAFTK", "length": 298 }, "evidence": [ { "id": "R4GJZ6", "url": "https://omabrowser.org/oma/group/R4GJZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQ93-1", "protein_name": "Golgi phosphoprotein 3 homolog sauron", "gene_name": "sau", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRSDGLVRRSVKPRENGGAEGGLNANTPDDNQDALDNLKDQEDNIDDGDSKETRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRVMIEKSGMRRRGLCTRKLILKSDQQTGDVLLDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLSDNVVKCRLVKKIQDSVLSKWVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYEVAMKRVRELLDLDFEAESAKPNANEILWAVFMAFTK", "length": 294 }, "evidence": [ { "id": "R4GJZ6", "url": "https://omabrowser.org/oma/group/R4GJZ6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" }, { "name": "Golgi vesicle budding", "id": "GO:0048194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048194", "evidence": [ { "database": "UniProtKB", "id": "R4GJZ6", "url": "https://www.uniprot.org/uniprotkb/R4GJZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": 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"url": "https://www.orthodb.org/?gene=R4GKL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:R4GKL8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:R4GKL8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_425002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425002", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKL8-1", "url": "https://www.uniprot.org/uniprotkb/R4GKL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEKDFISWHLLALIFLPFCLCQEEYMEVSRRSYKPVAKVLQSHHQTGHKGSRSREILKQRSQLIEWTVANSSSTDQNVLRPEVDDVELTTSDRVQPPQTGPQNPDCSSCCRGDFGVRLYQGPPGPPGPPGMPGNHGNNGNNGATGQEGAKGEKGDKGDMGPRGERGHHGPKGEKGYPGIPPELQVAFMASMATHFSNQNSGIIFSSVETNVGNFFDVMTGRFGAPVNGVYFFTFNMMKHEDVEEVYVYLMHNGNTVFSLYSYESKGKADTSGNSAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 314, "header": "tr|R4GKL8-1|R4GKL8_CHICK Isoform 1 of C1q and TNF related 3 OS=Gallus gallus OX=9031 GN=C1QTNF3 PE=1 SV=4 CANONICAL=R4GKL8-1" }, "isoforms": [ { "isoform_ac": "R4GKL8-1", "url": "https://www.uniprot.org/uniprotkb/R4GKL8/entry#R4GKL8-1", "sequence": { "sequence": "MAEKDFISWHLLALIFLPFCLCQEEYMEVSRRSYKPVAKVLQSHHQTGHKGSRSREILKQRSQLIEWTVANSSSTDQNVLRPEVDDVELTTSDRVQPPQTGPQNPDCSSCCRGDFGVRLYQGPPGPPGPPGMPGNHGNNGNNGATGQEGAKGEKGDKGDMGPRGERGHHGPKGEKGYPGIPPELQVAFMASMATHFSNQNSGIIFSSVETNVGNFFDVMTGRFGAPVNGVYFFTFNMMKHEDVEEVYVYLMHNGNTVFSLYSYESKGKADTSGNSAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 314, "header": "tr|R4GKL8-1|R4GKL8_CHICK Isoform 1 of C1q and TNF related 3 OS=Gallus gallus OX=9031 GN=C1QTNF3 PE=1 SV=4 CANONICAL=R4GKL8-1" }, "locus": { "chromosome": "Z", "start_pos": 10943004, "end_pos": 10928318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031700.1", "url": "https://www.ensembl.org/id/ENSGALT00010031700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018548.1", "url": "https://www.ensembl.org/id/ENSGALP00010018548.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9BXJ4-1", "protein_name": "Complement C1q tumor necrosis factor-related protein 3", "gene_name": "C1QTNF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 246 }, "evidence": [ { "id": "R4GKL8", "url": "https://omabrowser.org/oma/group/R4GKL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "maintenance of synapse structure", "id": "GO:0099558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099558", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "negative regulation of monocyte chemotactic protein-1 production", "id": "GO:0071638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071638", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "intracellular triglyceride homeostasis", "id": "GO:0035356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035356", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "positive regulation of adiponectin secretion", "id": "GO:0070165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070165", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" }, { "name": "trans-synaptic signaling, modulating synaptic transmission", "id": "GO:0099550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099550", "evidence": [ { "database": "UniProtKB", "id": "R4GKL8", "url": "https://www.uniprot.org/uniprotkb/R4GKL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GKL8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GKL8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GKL8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GKR4-1", "uniprot_ac": "R4GKR4", "uniprot_id": "R4GKR4_CHICK", "mass": { "chemical_mass": 24888.0, "monoisotopic_mass": 24888.0 }, "refseq": { "ac": "XP_416821", "name": "collectrin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416821" }, "gene_names": [ { "name": "TMEM27", "type": "recommended", "evidence": [ { "id": "R4GKR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ] }, { "name": "TMEM27", "type": "synonym", "evidence": [ { "id": "XP_416821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416821" } ] } ], "protein_names": [ { "name": "Collectrin, amino acid transport regulator", "type": "synonym", "evidence": [ { "id": "R4GKR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR4/entry#names_and_taxonomy" } ] }, { "name": "collectrin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416821" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416821.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416821" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM27", "url": "https://www.uniprot.org/uniprotkb/R4GKR4", "locus": {} } ], "crossref": [ { "id": "R4GKR4", "url": "https://alphafold.ebi.ac.uk/entry/R4GKR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029168", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418622", "url": "https://www.ncbi.nlm.nih.gov/gene/418622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AYEWNES", "url": "https://omabrowser.org/oma/group/AYEWNES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GKR4", "url": "https://www.orthodb.org/?gene=R4GKR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46884:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46884:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416821", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKR4-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGVLLLAFSVVSVASAELCKPDAQNAFKVRLSIKTALGDNAYAWDANEEYLFKAMIAFTMRRYSSKSTTQISNVLLCNVTDRVSFWFVVTDSSKNTTTVPGSEVEAAIRMNRNRINSAFLLSDKTLQFLKISTTLSPPVEPSTPVWLIVFGVVLSLIVAGIVFLVVSGIQQRKKKNKESTERENLEEKGEVTITIENGIPCETLDLKAGHVNGVFAADDERFTSL", "length": 226, "header": "tr|R4GKR4-1|R4GKR4_CHICK Isoform 1 of Collectrin, amino acid transport regulator OS=Gallus gallus OX=9031 GN=TMEM27 PE=4 SV=3 CANONICAL=R4GKR4-1" }, "isoforms": [ { "isoform_ac": "R4GKR4-1", "url": "https://www.uniprot.org/uniprotkb/R4GKR4/entry#R4GKR4-1", "sequence": { "sequence": "MLGVLLLAFSVVSVASAELCKPDAQNAFKVRLSIKTALGDNAYAWDANEEYLFKAMIAFTMRRYSSKSTTQISNVLLCNVTDRVSFWFVVTDSSKNTTTVPGSEVEAAIRMNRNRINSAFLLSDKTLQFLKISTTLSPPVEPSTPVWLIVFGVVLSLIVAGIVFLVVSGIQQRKKKNKESTERENLEEKGEVTITIENGIPCETLDLKAGHVNGVFAADDERFTSL", "length": 226, "header": "tr|R4GKR4-1|R4GKR4_CHICK Isoform 1 of Collectrin, amino acid transport regulator OS=Gallus gallus OX=9031 GN=TMEM27 PE=4 SV=3 CANONICAL=R4GKR4-1" }, "locus": { "chromosome": "1", "start_pos": 122029270, "end_pos": 122011073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003507.1", "url": "https://www.ensembl.org/id/ENSGALT00010003507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001949.1", "url": "https://www.ensembl.org/id/ENSGALP00010001949.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061HUM1-1", "protein_name": "Collectrin isoform X1", "gene_name": "Cltrn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLWLLLFLVTAIHAELCHPDAENAFKVRLSIRTALGDKAYVWDTDEEYLFRAMVAFSMRKVPNRETTEISHVLLCNVTQRVSFWFVVTDPSKNHTLPAAEVQSAIRMNRNRINSAFFLDDHTLEFLKIPSTLAPPPDASVPVWIIVFGVIFCIVVVAIALLVLSGIRQRRRNNKGPLGVEDAEDKCENIITIENGIPCDPLDTKGGLINDGFLTEDERLTPL", "length": 222 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A286ZI28-1", "protein_name": "Collectrin, amino acid transport regulator", "gene_name": "CLTRN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKVALSGGWNFFSLCLPCVFHSERMLWLLFFLVTSVRAELCQPDAENAFKVRLSIRTALGDKAYAWDTNEEYLFKAMLAFSMRKVPNRETTDISQVLLCNVTQRVSFWFVVTDPSKSHTLPAAEVQTAIRMNRNRINNAFFLNDQTLEFLRIPSTLAPPTEPSVPTWIIIFGVIFSITVVATMLLILSGIRERRRKNEGPSEMENTEDKCENTVTIENGIPCDPLDMKGGHINDAFGTEDERLTPL", "length": 247 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QQZ6-1", "protein_name": "Collectrin precursor", "gene_name": "cltrn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRVKVQMPSGEMITGFLLTIILLSPVVAQDLCKESKDGFKVRISLKTALGNDAYEWNESEKFLFRSTLAYAMRKKTGEDTYNIENILVCNDTKRVSFIFVVTLPADPTQLIPKEEVERAVRQSKHRINNAFLLSDMTLEFVGVPPTLAVPIQYNTPPWLIVFGVVIGIVAVGIVALLMSTVSKRRRAKAKDAGFDQDGDDEGIVKENGTALSGLNKKDGVYNQAFSNDERFTKL", "length": 234 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0VCT4-1", "protein_name": "Collectrin", "gene_name": "CLTRN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWLLFFLVTAIHADLCRPDAENAFKVRLSIRTALGDKAYAWDANEEYLFKAMVAFSMRKVPNRETTEISHVLLCNVTQRVSFWFVVTDPSRNHTLPAVEVQSAIRMNRNRINNAFFLNDQTLEFLRIPSTLAPPTDPSVPIWIIIFGVIFCIVLVATMLLIISGIRQHRRKNKGPSEMEDSEDKCENVITIENGIPCDPLDMKGGHINDAFVTEDERLTPL", "length": 222 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9ESG3-1", "protein_name": "Collectrin", "gene_name": "Cltrn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWALFFLVTTIHAELCRPDAENAFKVRLSIKAALGDKAYVWDTDEEYLFRAMVAFSMRKVPNREGTEISHVLLCNVTQRVSFWFVVTDPLKNHTLPAAEVQSAIRMNRNRINSAFFLDDHTLEFLKIPSTLAPPMDPSVPVWIIVFGVIFCIVTVAIALLVLSGIRQRRRNKKGPPGVEDAEDKCENIITIENGIPCDPLDMKGGHINDGFLTEDERLTPL", "length": 222 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESG4-1", "protein_name": "Collectrin", "gene_name": "Cltrn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWALFFLVTTIHAELCHPDAENAFKVRLSIRAALGDKAYVWDTDQEYLFRAMVAFSMRKVPNREATEISHVLLCNITQRVSFWFVVTDPSNNYTLPAAEVQSAIRKNRNRINSAFFLDDHTLEFLKIPSTLAPPMEPSVPVWIIVFGVIFCIVTVAIALLVLSGIRQRRRNNKGPPGVEDAEDKCENIITIENGIPCDPLDMKGGHINDGFLTEDERLTPL", "length": 222 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBJ8-1", "protein_name": "Collectrin", "gene_name": "CLTRN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWLLFFLVTAIHAELCQPGAENAFKVRLSIRTALGDKAYAWDTNEEYLFKAMVAFSMRKVPNREATEISHVLLCNVTQRVSFWFVVTDPSKNHTLPAVEVQSAIRMNKNRINNAFFLNDQTLEFLKIPSTLAPPMDPSVPIWIIIFGVIFCIIIVAIALLILSGIWQRRRKNKEPSEVDDAEDKCENMITIENGIPSDPLDMKGGHINDAFMTEDERLTPL", "length": 222 }, "evidence": [ { "id": "R4GKR4", "url": "https://omabrowser.org/oma/group/R4GKR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "transporter activator activity", "id": "GO:0141109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141109", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "SNARE complex assembly", "id": "GO:0035493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035493", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "positive regulation of amino acid transport", "id": "GO:0051957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051957", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "amino acid import across plasma membrane", "id": "GO:0089718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089718", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" }, { "name": "positive regulation of L-proline import across plasma membrane", "id": "GO:1905737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905737", "evidence": [ { "database": "UniProtKB", "id": "R4GKR4", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GKR4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 226, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GKR4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GKR4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GKR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKR4" }, { "id": "PS52010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Collectrin-like", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 226, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 79, "end_pos": 81 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GKX0-1", "uniprot_ac": "R4GKX0", "uniprot_id": "R4GKX0_CHICK", "mass": { "chemical_mass": 20982.0, "monoisotopic_mass": 20982.0 }, "refseq": { "ac": "XP_001233314", "name": "regulator of G-protein signaling 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233314" }, "gene_names": [ { "name": "RGS5", "type": "recommended", "evidence": [ { "id": "R4GKX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ] }, { "name": "RGS5", "type": "synonym", "evidence": [ { "id": "XP_001233314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233314" } ] } ], "protein_names": [ { "name": "Regulator of G-protein signaling 5", "type": "recommended", "evidence": [ { "id": "R4GKX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GKX0/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 5", "type": "synonym", "evidence": [ { "id": "XP_001233314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233314" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233314" } ] }, { "annotation": "Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.", "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0#function" }, { "database": "UniProtKB", "id": "ARBA00025071", "url": "https://www.uniprot.org/uniprotkb/ARBA00025071#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS5", "url": "https://www.uniprot.org/uniprotkb/R4GKX0", "locus": { "chromosome": "8", "start_pos": 3692771, "end_pos": 3699817, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012829", "url": "https://www.ensembl.org/id/ENSGALG00010012829" } ] } } ], "crossref": [ { "id": "R4GKX0", "url": "https://alphafold.ebi.ac.uk/entry/R4GKX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026572", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026572", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769998", "url": "https://www.ncbi.nlm.nih.gov/gene/769998", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769998", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769998", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIIPYPD", "url": "https://omabrowser.org/oma/group/FIIPYPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GKX0", "url": "https://www.orthodb.org/?gene=R4GKX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKX0-1", "url": "https://www.uniprot.org/uniprotkb/R4GKX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCKGLAALPHTCLERAKEIKTKLGTLLQKPDSAIDFIIPYPEKPEKPAKALKPSPEEVLQWRDSLEKLLQNPYGLASFRSFLCSEFSEENVEFWVACEDYKKTKSPVKMEEKAKRIYEEFIQTEAPKEVNIDHFTKAVTMKNLVEPSPSSFDMAQKRIFALMEKDSLPRFVRSEFYQELIK", "length": 181, "header": "tr|R4GKX0-1|R4GKX0_CHICK Isoform 1 of Regulator of G-protein signaling 5 OS=Gallus gallus OX=9031 GN=RGS5 PE=4 SV=1 CANONICAL=R4GKX0-1" }, "isoforms": [ { "isoform_ac": "R4GKX0-1", "url": "https://www.uniprot.org/uniprotkb/R4GKX0/entry#R4GKX0-1", "sequence": { "sequence": "MCKGLAALPHTCLERAKEIKTKLGTLLQKPDSAIDFIIPYPEKPEKPAKALKPSPEEVLQWRDSLEKLLQNPYGLASFRSFLCSEFSEENVEFWVACEDYKKTKSPVKMEEKAKRIYEEFIQTEAPKEVNIDHFTKAVTMKNLVEPSPSSFDMAQKRIFALMEKDSLPRFVRSEFYQELIK", "length": 181, "header": "tr|R4GKX0-1|R4GKX0_CHICK Isoform 1 of Regulator of G-protein signaling 5 OS=Gallus gallus OX=9031 GN=RGS5 PE=4 SV=1 CANONICAL=R4GKX0-1" }, "locus": { "chromosome": "8", "start_pos": 3699781, "end_pos": 3695379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030769.1", "url": "https://www.ensembl.org/id/ENSGALT00010030769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017844.1", "url": "https://www.ensembl.org/id/ENSGALP00010017844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769998", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769998", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "O08850-1", "protein_name": "Regulator of G protein signaling 5", "gene_name": "Rgs5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQNSYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPRSFDLAQKRIYALMEKDSLPRFVRSEFYKELIK", "length": 181 }, "evidence": [ { "id": "R4GKX0", "url": "https://omabrowser.org/oma/group/R4GKX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O15539-1", "protein_name": "Regulator of G protein signaling 5", "gene_name": "RGS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK", "length": 181 }, "evidence": [ { "id": "R4GKX0", "url": "https://omabrowser.org/oma/group/R4GKX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49800-1", "protein_name": "Regulator of G protein signaling 5", "gene_name": "Rgs5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQSNYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLAQKRIYALMEKDSLPRFVRSEFYKELIN", "length": 181 }, "evidence": [ { "id": "R4GKX0", "url": "https://omabrowser.org/oma/group/R4GKX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3T0T8-1", "protein_name": "Regulator of G protein signaling 5", "gene_name": "RGS5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCKGLAALPHSCLERAKEIKIKLGILLQKPESAIDLVIPYNEKPEKPAKTQKPSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWMACEDYKKIKSPVKMAETAKKIYEEFIQVEAPKEVNIDHFTKEITVKNLVEPSPSSFDVAQKRIHALMEKDSLPRFVRSEFYQEFIK", "length": 181 }, "evidence": [ { "id": "R4GKX0", "url": "https://omabrowser.org/oma/group/R4GKX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "R4GKX0", "url": "https://www.uniprot.org/uniprotkb/R4GKX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GKX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 181, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GKX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GKX0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GL30-1", "uniprot_ac": "R4GL30", "uniprot_id": "R4GL30_CHICK", "mass": { "chemical_mass": 25396.0, "monoisotopic_mass": 25396.0 }, "refseq": { "ac": "XP_419897", "name": "BAG family molecular chaperone regulator 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419897" }, "gene_names": [ { "name": "BAG2", "type": "recommended", "evidence": [ { "id": "R4GL30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ] }, { "name": "BAG2", "type": "synonym", "evidence": [ { "id": "XP_419897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419897" } ] } ], "protein_names": [ { "name": "BAG cochaperone 2", "type": "synonym", "evidence": [ { "id": "R4GL30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GL30/entry#names_and_taxonomy" } ] }, { "name": "BAG family molecular chaperone regulator 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419897" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_419897.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BAG2", "url": "https://www.uniprot.org/uniprotkb/R4GL30", "locus": { "chromosome": "3", "start_pos": 86440838, "end_pos": 86449426, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002342", "url": "https://www.ensembl.org/id/ENSGALG00010002342" } ] } } ], "crossref": [ { "id": "R4GL30", "url": "https://alphafold.ebi.ac.uk/entry/R4GL30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026605", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026605", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421880", "url": "https://www.ncbi.nlm.nih.gov/gene/421880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421880", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHATKMI", "url": "https://omabrowser.org/oma/group/LHATKMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GL30", "url": "https://www.orthodb.org/?gene=R4GL30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12334:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12334:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_419897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GL30-1", "url": "https://www.uniprot.org/uniprotkb/R4GL30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQAKISAKASEGAPPQQQQQQPSAGQLRGRFYRSTSMADRSSRLLENLDQLELRVEAFRDAASAMEQEKETLLEMIHNIQNSQDMRHISEGEREELNLTANRLMGRTLTVEVSVETIRNAQQQESLLHATRMIDEIVNKLLDDLEDAKIRLMSLYGACTSDVPAGPIDQKFQSVVIGCAIEDQKKIKRRLETLLRNLENSEKSITLLEHQKSSMRQSCNTKQD", "length": 224, "header": "tr|R4GL30-1|R4GL30_CHICK Isoform 1 of BAG cochaperone 2 OS=Gallus gallus OX=9031 GN=BAG2 PE=1 SV=2 CANONICAL=R4GL30-1" }, "isoforms": [ { "isoform_ac": "R4GL30-1", "url": "https://www.uniprot.org/uniprotkb/R4GL30/entry#R4GL30-1", "sequence": { "sequence": "MAQAKISAKASEGAPPQQQQQQPSAGQLRGRFYRSTSMADRSSRLLENLDQLELRVEAFRDAASAMEQEKETLLEMIHNIQNSQDMRHISEGEREELNLTANRLMGRTLTVEVSVETIRNAQQQESLLHATRMIDEIVNKLLDDLEDAKIRLMSLYGACTSDVPAGPIDQKFQSVVIGCAIEDQKKIKRRLETLLRNLENSEKSITLLEHQKSSMRQSCNTKQD", "length": 224, "header": "tr|R4GL30-1|R4GL30_CHICK Isoform 1 of BAG cochaperone 2 OS=Gallus gallus OX=9031 GN=BAG2 PE=1 SV=2 CANONICAL=R4GL30-1" }, "locus": { "chromosome": "3", "start_pos": 86449334, "end_pos": 86442304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005294.1", "url": "https://www.ensembl.org/id/ENSGALT00010005294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003133.1", "url": "https://www.ensembl.org/id/ENSGALP00010003133.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421880", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421880", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AV76-1", "protein_name": "BAG family molecular chaperone regulator 2", "gene_name": "BAG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQARISAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEVLLEMIHSIQNSQDMRQISEGEREELNLTANRLMGRTLTVEVSVETIRNPQQQESLKQATRIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPAGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGASKTLQQNTESRFN", "length": 210 }, "evidence": [ { "id": "R4GL30", "url": "https://omabrowser.org/oma/group/R4GL30/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1PFF3-1", "protein_name": "BAG family molecular chaperone regulator 2", "gene_name": "bag2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQAKINAKMNDATKNKFTRTMSMADRSGRLLESLDQIEMRVEALREEASAMEQERECLIEMIQSIQNSQEMRSICDGEREELSLTAARLMGRTLTVKVSLETIRNQQQEEALQKAMKMIDEITEKVLEDLQSARTRLEALHAACVSDAPPVPVDQKFQSVVISCALEDQKKIKRRLETLIRNMDNAEKTIQIMDNPKVDLSKLANGK", "length": 208 }, "evidence": [ { "id": "R4GL30", "url": "https://omabrowser.org/oma/group/R4GL30/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95816-1", "protein_name": "BAG family molecular chaperone regulator 2", "gene_name": "BAG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQAKINAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQQESLKHATRIIDEVVNKFLDDLGNAKSHLMSLYSACSSEVPHGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSKTLQQNAESRFN", "length": 211 }, "evidence": [ { "id": "R4GL30", "url": "https://omabrowser.org/oma/group/R4GL30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBG5-1", "protein_name": "BAG family molecular chaperone regulator 2", "gene_name": "BAG2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQARISAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEVLLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRSPQQQESLKHATRIIDEVVSKFLDDLGNARSHLMSLYSACSSEVPAGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENADKAIKLLEHSKGAASKTLQQNAEARFN", "length": 211 }, "evidence": [ { "id": "R4GL30", "url": "https://omabrowser.org/oma/group/R4GL30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q91YN9-1", "protein_name": "BAG family molecular chaperone regulator 2", "gene_name": "Bag2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQAKISAKAHEGRFCRSSSMADRSSRLLESLDQLELRVEALRDAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQEESLKHATRIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPPGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIDNSDKAIKLLEHAKGAGSKSLQNTDGKFN", "length": 210 }, "evidence": [ { "id": "R4GL30", "url": "https://omabrowser.org/oma/group/R4GL30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" }, { "name": "protein folding chaperone complex", "id": "GO:0101031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101031", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" }, { "name": "dendritic microtubule", "id": "GO:1901588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901588", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" } ] }, { "name": "Molecular Function", 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"" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" }, { "name": "tau protein binding", "id": "GO:0048156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048156", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", "url": "https://www.uniprot.org/uniprotkb/R4GL30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of protein processing", "id": "GO:0010954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010954", "evidence": [ { "database": "UniProtKB", "id": "R4GL30", 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[ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000074.1. On Apr 28, 2013 this sequence version replaced XP_420622.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001264849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264849" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CETN4", "url": "https://www.uniprot.org/uniprotkb/R4GLB5", "locus": { "chromosome": "4", "start_pos": 53153598, "end_pos": 53148672, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004225", "url": "https://www.ensembl.org/id/ENSGALG00010004225" } ] } } ], "crossref": [ { "id": "R4GLB5", "url": "https://alphafold.ebi.ac.uk/entry/R4GLB5", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264849", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLB5-1", "url": "https://www.uniprot.org/uniprotkb/R4GLB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNYRKPGLSTAQRKKSGLKPELTEEQKQEIREAFDLFDTDGSGSIDIKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTIDFEDFLAMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY", "length": 171, "header": "tr|R4GLB5-1|R4GLB5_CHICK Isoform 1 of Centrin 4 OS=Gallus gallus OX=9031 GN=CETN4 PE=1 SV=1 CANONICAL=R4GLB5-1" }, "isoforms": [ { "isoform_ac": "R4GLB5-1", "url": "https://www.uniprot.org/uniprotkb/R4GLB5/entry#R4GLB5-1", "sequence": { "sequence": 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"" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" }, { "name": "heterotrimeric G-protein binding", "id": "GO:0032795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032795", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "R4GLB5", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GLB5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 171, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GLB5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GLB5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLB5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 62, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GLI3-1", "uniprot_ac": "R4GLI3", "uniprot_id": "R4GLI3_CHICK", "mass": { "chemical_mass": 35526.0, "monoisotopic_mass": 35526.0 }, "refseq": { "ac": "XP_003642840", "name": "homeobox protein Hox-B2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642840" }, "gene_names": [ { "name": "HOXB2", "type": "recommended", "evidence": [ { "id": "R4GLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ] }, { "name": "HOXB2", "type": "synonym", "evidence": [ { "id": "XP_003642840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642840" } ] } ], "protein_names": [ { "name": "Homeobox B2", "type": "synonym", "evidence": [ { "id": "R4GLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLI3/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-B2", "type": "synonym", "evidence": [ { "id": "XP_003642840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642840" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642840" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXB2", "url": "https://www.uniprot.org/uniprotkb/R4GLI3", "locus": { "chromosome": "27", "start_pos": 3479760, "end_pos": 3476821, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023438", "url": "https://www.ensembl.org/id/ENSGALG00010023438" } ] } } ], "crossref": [ { "id": "R4GLI3", "url": "https://alphafold.ebi.ac.uk/entry/R4GLI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000025774", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000025774", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429940", "url": "https://www.ncbi.nlm.nih.gov/gene/429940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429940", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLPHFNF", "url": "https://omabrowser.org/oma/group/DLPHFNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GLI3", "url": "https://www.orthodb.org/?gene=R4GLI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLI3-1", "url": "https://www.uniprot.org/uniprotkb/R4GLI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSLPAVLETFQTSSIKDSTLIPPPFEQTVLSLNPCSSSQARPRSQKRASHGLLQPQPPAQPGPLAAEFPWMKEKKSSKKATQAPSSSSSSFPPSSSSVPIPAAGSPADTQGLADSSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQYKEPPDGDIAYPGLDEGSEATDEAEESPALGPCPGPYRGAQPEQPRSPRGTDRPGAPPSELGFPESQGSPWLPELSILSAESCLQLSPALQDSLESPLHFSEEDLDFFTSALCTIDLQHFNFQ", "length": 323, "header": "tr|R4GLI3-1|R4GLI3_CHICK Isoform 1 of Homeobox B2 OS=Gallus gallus OX=9031 GN=HOXB2 PE=3 SV=3 CANONICAL=R4GLI3-1" }, "isoforms": [ { "isoform_ac": "R4GLI3-1", "url": "https://www.uniprot.org/uniprotkb/R4GLI3/entry#R4GLI3-1", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSLPAVLETFQTSSIKDSTLIPPPFEQTVLSLNPCSSSQARPRSQKRASHGLLQPQPPAQPGPLAAEFPWMKEKKSSKKATQAPSSSSSSFPPSSSSVPIPAAGSPADTQGLADSSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQYKEPPDGDIAYPGLDEGSEATDEAEESPALGPCPGPYRGAQPEQPRSPRGTDRPGAPPSELGFPESQGSPWLPELSILSAESCLQLSPALQDSLESPLHFSEEDLDFFTSALCTIDLQHFNFQ", "length": 323, "header": "tr|R4GLI3-1|R4GLI3_CHICK Isoform 1 of Homeobox B2 OS=Gallus gallus OX=9031 GN=HOXB2 PE=3 SV=3 CANONICAL=R4GLI3-1" }, "locus": { "chromosome": "27", "start_pos": 3479213, "end_pos": 3477004, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057108.1", "url": "https://www.ensembl.org/id/ENSGALT00010057108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034739.1", "url": "https://www.ensembl.org/id/ENSGALP00010034739.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429940", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGM8-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTYPSLQPGASTLQRPGSQKQAEDGPALRPPPPLAAPPAPEFPWMKEKKSAKKPSQSAASPSPAASSVRVSGVGSPSDGPGLSESGGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGDPGGPSAPDDSGDPAEESAVSPGPASASHRLREACFLPAEAAQGPQGAPPPAPPATSLESMGAPSPGCTMLRARGLQPETLPEDTCPEQPDSPFLPDLNFFAADSCLQMSGGLSPSLQSSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A426-1", "protein_name": "Homeobox B2", "gene_name": "Hoxb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPPLEQTFPSLQLGASTLQRPGSQKPAGDGPALRPPPPLPVAPPAPEFPWMKEKKSAKKPSQSAATPSPAASSVRASGVGSPSDGPGLPESGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPGGLSAQDDAGEPAEEPTVSPGDVASHRLREACFLPAEAAQGPRGAPPPLPPATALESVGASSPGCTMLRAGGLQSEPLPEDACPERQDSPFLPDLNFFAADSCLPMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 355 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGM6-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPLPPLPAAPLAPEFPWMKEKKSAKKPSQSAASPPAASSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALRNTGEPAEEPVASPGRPSVLQASRAACCLTPEVAQGPPGVSGPRALAARVEGADARSPGGALRGAGGREPEPLPEDAFSERQDSPFLPDLSFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RWG7-1", "protein_name": "Homeobox B2", "gene_name": "HOXB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPSPPPFEQTFPSLQPGASTLQRPGSQKRAEDGPALPPPPPPLPATPLAPEFPWMKEKKSAKKPSQSATSPTAAFSVLASGVGSPADGPGLPEAAGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGGPACPGAPKKAGEASEEPLASPGRPSVSRAAREVCCQPPEVAPGPLGAPGLRPLAARVEGAGARSPGGELRGAGGLEPERLPEDAFPERPYSPFLPDLSFFAADSCLQLSGGLSPSLSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 353 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C1T1-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "Hoxb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPLEQTFPSLQLGASTLQRPGSQKQAGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPSAQDDAGEPAEEPTVSPGDVATHRLREACFHPAEAAQGPRGAPPSALPATTLESVGASSPGCTMLRAGGRQSEPLPEDACPERQDSPFLPDLNFFAADSCLQMSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 354 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P14652-1", "protein_name": "Homeobox protein Hox-B2", "gene_name": "HOXB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP", "length": 356 }, "evidence": [ { "id": "R4GLI3", "url": "https://omabrowser.org/oma/group/R4GLI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "R4GLI3", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GLI3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GLI3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GLI3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLI3" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 140, "end_pos": 199, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GLV7-1", "uniprot_ac": "R4GLV7", "uniprot_id": "R4GLV7_CHICK", "mass": { "chemical_mass": 81080.0, "monoisotopic_mass": 81080.0 }, "refseq": { "ac": "XP_040505327", "name": "transcription termination factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505327" }, "gene_names": [ { "name": "TTF1", "type": "recommended", "evidence": [ { "id": "R4GLV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ] }, { "name": "TTF1", "type": "synonym", "evidence": [ { "id": "XP_040505327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505327" } ] } ], "protein_names": [ { "name": "Transcription termination factor 1", "type": "synonym", "evidence": [ { "id": "R4GLV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GLV7/entry#names_and_taxonomy" } ] }, { "name": "transcription termination factor 1", "type": "synonym", "evidence": [ { "id": "XP_040505327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505327" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505327" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTF1", "url": "https://www.uniprot.org/uniprotkb/R4GLV7", "locus": { "chromosome": "17", "start_pos": 7126119, "end_pos": 7133786, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028772", "url": "https://www.ensembl.org/id/ENSGALG00010028772" } ] } } ], "crossref": [ { "id": "R4GLV7", "url": "https://alphafold.ebi.ac.uk/entry/R4GLV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027242", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027242", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417169", "url": "https://www.ncbi.nlm.nih.gov/gene/417169", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PECIYLE", "url": "https://omabrowser.org/oma/group/PECIYLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GLV7", "url": "https://www.orthodb.org/?gene=R4GLV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5683826", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73863", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GLV7-1", "url": "https://www.uniprot.org/uniprotkb/R4GLV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEKAHGDDFPLWDSHKKKKKRKRRRSDVGHENGSMQDAELSCASPQLSEDHTAQSSEVSKKKKKRKKKNKGEEQQPLLENSVSELEGEVGGEAVMSASQRKKKKRKRKLSEGTDGHSDVDCVSVNQNCADSSQEDDADVCFKKSVKKKRKRKLPEEDGVSESPASETPGKTGSKRLKKKKRRVSHTQDTQEDTDVTVDESLLTCPEQKKQGEDVESPSTTGEGGVAAAQCRGSACGASPAVSEDPTDAPTDSSKPAEEAKKSSRRAAKVIKSRTYITEDSSSDSDVMTPETSTSDKKEDQNNSFTETTATGELSVDDEEFLHLFTVLDLDTAKQELGEFIPHVGQLSDHSIRKMAGRDLLRFKQFKKQGIAIKFGRFSQKENNQIRKNVEDFLSITGIDSAEKLLFTSRYPEEKGAINRLKAEHLFCEKLAEGIPRAWRLIYYRARKIFDPNNYKGRYTKEEKERLKRYHAVHGNDWKKIAEKMSRSNLSVAMKYSEIKSPINYGPWSKEEIQRLMRAVEEVIIKRTKLENANSLSSSKKSHRSLQIDREKLFQKLPWTEIETKVGTRYWRQCKQKWTSILTNKITKGQQLHRGTKGLQASINLIKRLYEMKVEDANEINWEELSDIIGDVPGSYVQAKFYKLKVTYVPFWRAKTFSEIIVHLFEETLPELEQKLEKRKRKQSNSSDATVNPKKQVFQLSDVFDSSEESDD", "length": 712, "header": "tr|R4GLV7-1|R4GLV7_CHICK Isoform 1 of Transcription termination factor 1 OS=Gallus gallus OX=9031 GN=TTF1 PE=4 SV=3 CANONICAL=R4GLV7-1" }, "isoforms": [ { "isoform_ac": "R4GLV7-1", "url": "https://www.uniprot.org/uniprotkb/R4GLV7/entry#R4GLV7-1", "sequence": { "sequence": "MTEKAHGDDFPLWDSHKKKKKRKRRRSDVGHENGSMQDAELSCASPQLSEDHTAQSSEVSKKKKKRKKKNKGEEQQPLLENSVSELEGEVGGEAVMSASQRKKKKRKRKLSEGTDGHSDVDCVSVNQNCADSSQEDDADVCFKKSVKKKRKRKLPEEDGVSESPASETPGKTGSKRLKKKKRRVSHTQDTQEDTDVTVDESLLTCPEQKKQGEDVESPSTTGEGGVAAAQCRGSACGASPAVSEDPTDAPTDSSKPAEEAKKSSRRAAKVIKSRTYITEDSSSDSDVMTPETSTSDKKEDQNNSFTETTATGELSVDDEEFLHLFTVLDLDTAKQELGEFIPHVGQLSDHSIRKMAGRDLLRFKQFKKQGIAIKFGRFSQKENNQIRKNVEDFLSITGIDSAEKLLFTSRYPEEKGAINRLKAEHLFCEKLAEGIPRAWRLIYYRARKIFDPNNYKGRYTKEEKERLKRYHAVHGNDWKKIAEKMSRSNLSVAMKYSEIKSPINYGPWSKEEIQRLMRAVEEVIIKRTKLENANSLSSSKKSHRSLQIDREKLFQKLPWTEIETKVGTRYWRQCKQKWTSILTNKITKGQQLHRGTKGLQASINLIKRLYEMKVEDANEINWEELSDIIGDVPGSYVQAKFYKLKVTYVPFWRAKTFSEIIVHLFEETLPELEQKLEKRKRKQSNSSDATVNPKKQVFQLSDVFDSSEESDD", "length": 712, "header": "tr|R4GLV7-1|R4GLV7_CHICK Isoform 1 of Transcription termination factor 1 OS=Gallus gallus OX=9031 GN=TTF1 PE=4 SV=3 CANONICAL=R4GLV7-1" }, "locus": { "chromosome": "17", "start_pos": 7133587, "end_pos": 7127020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069626.1", "url": "https://www.ensembl.org/id/ENSGALT00010069626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042887.1", "url": "https://www.ensembl.org/id/ENSGALP00010042887.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "resource": "Reactome", "description": "Surfactant metabolism" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B2X7-1", "protein_name": "Transcription termination factor 1.2", "gene_name": "ttf1.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEMQSDSPNNVDGEKMKKKKISKTTEQHELTESPQEQTEKRRKKKKKKRRDSTTECDDDLQTDTGKKKKRRKLDNEGETSVMDDGVSDQHEAQTQELPGSSEEKTSRRLKARVSATQTSHAEMTEEEQTDTETEHEEEPNTSDDEESGPPDVVIGTGWRKSRKIPVDLKLLAELKEFCPNTAIESQSDTEINKMIKYDLPRFREFKKQGIAMRHGRFSKAENEKLRQNVSDLLALTQLKDAVMLFHPKRFLNEEMKLAELKRMYGFYQKIAEGIPRPCHDVYTRGKKMFDHRHYKGNFTEEEDKRLLKYYNLYGPNWKKISEKTGRSSFSLRKRFPQISSVKRKGPWTPEEVQRLLRAVREHVLSVLKSANPNKKKPKRVRREILYENLPWTTIADKVETRCYRQCREKWMSILFTRMSSGTTFRGKAGLLAKIRLIKAMYEMQVEDVADIDWESLTAAFGNVPPAHVQKMWRKIKNYYLPDWNSRSFKDNVSHLHKNILPCLVSSCKGFDVNAVKVEQKELFRLSKIFKDIEEDGQDIEEDGQDIEEDGRDGDEETGEQENNSFN", "length": 567 }, "evidence": [ { "id": "R4GLV7", "url": "https://omabrowser.org/oma/group/R4GLV7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "R4GLV7", "url": "https://www.uniprot.org/uniprotkb/R4GLV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GLV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 712, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GLV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GLV7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 247 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 685, "end_pos": 687 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GM14-1", "uniprot_ac": "R4GM14", "uniprot_id": "R4GM14_CHICK", "mass": { "chemical_mass": 73255.0, "monoisotopic_mass": 73255.0 }, "refseq": { "ac": "XP_015146363", "name": "dual specificity protein phosphatase 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146363" }, "gene_names": [ { "name": "DUSP16", "type": "recommended", "evidence": [ { "id": "R4GM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ] }, { "name": "DUSP16", "type": "synonym", "evidence": [ { "id": "XP_015146363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146363" } ] } ], "protein_names": [ { "name": "Dual specificity phosphatase 16", "type": "synonym", "evidence": [ { "id": "R4GM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM14/entry#names_and_taxonomy" } ] }, { "name": "dual specificity protein phosphatase 16", "type": "synonym", "evidence": [ { "id": "XP_015146363", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146363" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015146363.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146363" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DUSP16", "url": "https://www.uniprot.org/uniprotkb/R4GM14", "locus": { "chromosome": "1", "start_pos": 71954564, "end_pos": 72024309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021661", "url": "https://www.ensembl.org/id/ENSGALG00010021661" } ] } } ], "crossref": [ { "id": "R4GM14", "url": "https://alphafold.ebi.ac.uk/entry/R4GM14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028155", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431336", "url": "https://www.ncbi.nlm.nih.gov/gene/431336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EGIMSEN", "url": "https://omabrowser.org/oma/group/EGIMSEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GM14", "url": "https://www.orthodb.org/?gene=R4GM14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10159:SF343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10159:SF343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146363", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GM14-1", "url": "https://www.uniprot.org/uniprotkb/R4GM14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEMISTQLIVAEKLVALLESGTEKLLLIDSRPFVEYNTSHILDAININCSKLMKRRLQQDKVLITELIQHSAKHKIEIDCKQEVVVYDQSSKDVTSLSPDCFLTVLLGKLEKNFISVCLLSGGFAEFSSSFPGLCEGKSTLVPTCISQPCLPVSNIGPTRILPHLYLGCQRDVLNKEMIQQNDIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGRVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDFEKKIKNQSGQPGHISKLKLLHLEKSSEHVLVPEGGQSSLATSQLCITATSEIVESKPADPGSVPCTHLPSLEDSPLVQGINGLHVSLDKVEDSNRLKRSFSLDIKSVSYSAASSCVTASVQGFTSSEDTLEYYKHATALEGSSKLCQFSPVQEVSEQTPEASPDKEEANPPKKPQNAWQLDSQSKRQHMGRSSGGAVTQRALLYPLHRSGSVEDNYRTNFLFGLSTSQQHLAKSAAGLGLKGWHSDILAPQTSAPSLTNSWYFAAESSHFYSASAIYGNSAAYSAYSCSQLPTGCEQSCAVRRRTKQGNRGDSRRSWHEESSFEKQFKRRSCQMEFGESFISDNRSREELGKVGSQSSFSGSMEIIEVS", "length": 664, "header": "tr|R4GM14-1|R4GM14_CHICK Isoform 1 of Dual specificity phosphatase 16 OS=Gallus gallus OX=9031 GN=DUSP16 PE=3 SV=2 CANONICAL=R4GM14-1" }, "isoforms": [ { "isoform_ac": "R4GM14-1", "url": "https://www.uniprot.org/uniprotkb/R4GM14/entry#R4GM14-1", "sequence": { "sequence": "MADEMISTQLIVAEKLVALLESGTEKLLLIDSRPFVEYNTSHILDAININCSKLMKRRLQQDKVLITELIQHSAKHKIEIDCKQEVVVYDQSSKDVTSLSPDCFLTVLLGKLEKNFISVCLLSGGFAEFSSSFPGLCEGKSTLVPTCISQPCLPVSNIGPTRILPHLYLGCQRDVLNKEMIQQNDIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGRVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDFEKKIKNQSGQPGHISKLKLLHLEKSSEHVLVPEGGQSSLATSQLCITATSEIVESKPADPGSVPCTHLPSLEDSPLVQGINGLHVSLDKVEDSNRLKRSFSLDIKSVSYSAASSCVTASVQGFTSSEDTLEYYKHATALEGSSKLCQFSPVQEVSEQTPEASPDKEEANPPKKPQNAWQLDSQSKRQHMGRSSGGAVTQRALLYPLHRSGSVEDNYRTNFLFGLSTSQQHLAKSAAGLGLKGWHSDILAPQTSAPSLTNSWYFAAESSHFYSASAIYGNSAAYSAYSCSQLPTGCEQSCAVRRRTKQGNRGDSRRSWHEESSFEKQFKRRSCQMEFGESFISDNRSREELGKVGSQSSFSGSMEIIEVS", "length": 664, "header": "tr|R4GM14-1|R4GM14_CHICK Isoform 1 of Dual specificity phosphatase 16 OS=Gallus gallus OX=9031 GN=DUSP16 PE=3 SV=2 CANONICAL=R4GM14-1" }, "locus": { "chromosome": "1", "start_pos": 71987751, "end_pos": 71955554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052618.1", "url": "https://www.ensembl.org/id/ENSGALT00010052618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031524.1", "url": "https://www.ensembl.org/id/ENSGALP00010031524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-112409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112409", "resource": "Reactome", "description": "RAF-independent MAPK1/3 activation" }, { "id": "R-GGA-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MNA8-1", "protein_name": "Dual specificity protein phosphatase 16", "gene_name": "Dusp16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCNQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFFRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLMDYEKMIKKQTGMSGPKSKLKLLHLDKPSEPAASEGGRKSALSLSPPCANSTSEAAGQRLVHPTSVPSLQPSLLEDSPLVQAFNGLQLSAEQLEDSNKLKRSFSLDIKSVSYSASVAASLHGFSSEDALEYYKPSATLDGTNKLCQFSPVQEVSEQTPETSPDKEEAHIPKQPQPTRPSESQSKRLHSVRTSSGATQRPFFSPLQRSGSVEDNYHTNFLFGLSTSQQHLTKSTVGPGLKGWHSDILAPQSSAPSLTNSWYFATEPSHFYSASAIYGGSSSYSAYSCSQLPTCSDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS", "length": 658 }, "evidence": [ { "id": "R4GM14", "url": "https://omabrowser.org/oma/group/R4GM14/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A3W6-1", "protein_name": "Dual specificity phosphatase 16", "gene_name": "Dusp16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHEMTGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVGSLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANTGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMGQLMDYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRLVHPASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSEDAMEYYKPSATLDGTSKLCQFSPVQEVSEQTPETSPDKEEAHIPRQPQATRPSESQTTRLHSVRTSSTGSTQRPFFSPLHRSGSVEDNYHTNFLFGLSTSQQHLTKSAAGLGLKGWHSDILPPQSSAPSLTSGWYFATEPSHFYSASAIYGGNASYSAYSCSQLPTCSDQIYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEVIEVS", "length": 661 }, "evidence": [ { "id": "R4GM14", "url": "https://omabrowser.org/oma/group/R4GM14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAA9-1", "protein_name": "Dual specificity phosphatase 16", "gene_name": "DUSP16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDLDCSQKVVVYDQSSQDVASLASDCFLTVLLGKLEKSFSSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKRIKSQTGAAGPKSKLKLLPLEKPSESVAGPGPVEGAQGSQLPPGPPHGRPAPALSEGAGPRPAPPSTAPDDGPLVQALNGLHLPPDRLEDSGRLKRSFSLDIKSVTPTPGGLSSPEAALELYKPAASSLEGAGKPCQFSPVQEVSEQTPEASPDSEEAPPPRPSDGSGQGARPRPGRPLWSPLHRSGSVEDRGQPRFLFGLSASQQHLATSATGLGLEGWHSDLLAPQTSAPALTKSWYFAPEPPHFYSASAIYGGRTGHPAFSCSQLPTCSGDPGHSVRRRHKPGDRADSRRSWHEESPFEKQFKRRSCQMEFGESIRSENRSREELGKVGSQSSFSGSMEIIEVS", "length": 643 }, "evidence": [ { "id": "R4GM14", "url": "https://omabrowser.org/oma/group/R4GM14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9BY84-1", "protein_name": "Dual specificity protein phosphatase 16", "gene_name": "DUSP16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS", "length": 665 }, "evidence": [ { "id": "R4GM14", "url": "https://omabrowser.org/oma/group/R4GM14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "mitogen-activated protein kinase p38 binding", "id": "GO:0048273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048273", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "MAP kinase tyrosine/serine/threonine phosphatase activity", "id": "GO:0017017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017017", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "protein tyrosine/threonine phosphatase activity", "id": "GO:0008330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008330", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "JUN kinase binding", "id": "GO:0008432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008432", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "protein carrier chaperone", "id": "GO:0140597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140597", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" }, { "name": "MAP kinase tyrosine phosphatase activity", "id": "GO:0033550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033550", "evidence": [ { "database": "UniProtKB", "id": "R4GM14", "url": "https://www.uniprot.org/uniprotkb/R4GM14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GM14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 664, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GM14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GM14" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM14" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 138, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "R4GM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM14" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 282, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "R4GM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM14" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 301, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 639, "end_pos": 641 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GM18-1", "uniprot_ac": "R4GM18", "uniprot_id": "R4GM18_CHICK", "mass": { "chemical_mass": 25661.0, "monoisotopic_mass": 25661.0 }, "refseq": { "ac": "XP_003643067", "name": "Krueppel-like factor 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643067" }, "gene_names": [ { "name": "KLF9", "type": "recommended", "evidence": [ { "id": "R4GM18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ] }, { "name": "KLF9", "type": "synonym", "evidence": [ { "id": "XP_003643067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643067" } ] } ], "protein_names": [ { "name": "KLF transcription factor 9", "type": "synonym", "evidence": [ { "id": "R4GM18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM18/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 9", "type": "synonym", "evidence": [ { "id": "XP_003643067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643067" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643067" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF9", "url": "https://www.uniprot.org/uniprotkb/R4GM18", "locus": { "chromosome": "Z", "start_pos": 35632988, "end_pos": 35646170, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014987", "url": "https://www.ensembl.org/id/ENSGALG00010014987" } ] } } ], "crossref": [ { "id": "R4GM18", "url": "https://alphafold.ebi.ac.uk/entry/R4GM18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027374", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027374", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770238", "url": "https://www.ncbi.nlm.nih.gov/gene/770238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770238", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QINGHRC", "url": "https://omabrowser.org/oma/group/QINGHRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GM18", "url": "https://www.orthodb.org/?gene=R4GM18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643067", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GM18-1", "url": "https://www.uniprot.org/uniprotkb/R4GM18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVAYVDFVAAQCLVSISNRSAGPPSPEAAARLKVPGEAEAGREMRDPRDAWKDYCALLAIAKSLLELNKYRPLPAPSVCSDSLESPDEDAGSDSDAAATSPCSGPAPAPPSRLRGAAAAAAPKAKLAAEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKSSSGSL", "length": 235, "header": "tr|R4GM18-1|R4GM18_CHICK Isoform 1 of KLF transcription factor 9 OS=Gallus gallus OX=9031 GN=KLF9 PE=3 SV=1 CANONICAL=R4GM18-1" }, "isoforms": [ { "isoform_ac": "R4GM18-1", "url": "https://www.uniprot.org/uniprotkb/R4GM18/entry#R4GM18-1", "sequence": { "sequence": "MSAVAYVDFVAAQCLVSISNRSAGPPSPEAAARLKVPGEAEAGREMRDPRDAWKDYCALLAIAKSLLELNKYRPLPAPSVCSDSLESPDEDAGSDSDAAATSPCSGPAPAPPSRLRGAAAAAAPKAKLAAEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKSSSGSL", "length": 235, "header": "tr|R4GM18-1|R4GM18_CHICK Isoform 1 of KLF transcription factor 9 OS=Gallus gallus OX=9031 GN=KLF9 PE=3 SV=1 CANONICAL=R4GM18-1" }, "locus": { "chromosome": "Z", "start_pos": 35646022, "end_pos": 35633847, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036044.1", "url": "https://www.ensembl.org/id/ENSGALT00010036044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020927.1", "url": "https://www.ensembl.org/id/ENSGALP00010020927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770238", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "negative regulation of keratinocyte proliferation", "id": "GO:0010839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010839", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "cellular response to cortisol stimulus", "id": "GO:0071387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071387", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "R4GM18", "url": "https://www.uniprot.org/uniprotkb/R4GM18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GM18-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 235, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GM18-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GM18" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "R4GM18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GM18" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 163, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GMA8-1", "uniprot_ac": "R4GMA8", "uniprot_id": "R4GMA8_CHICK", "mass": { "chemical_mass": 27327.0, "monoisotopic_mass": 27327.0 }, "refseq": { "ac": "XP_025007684", "name": "nanos homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007684" }, "gene_names": [ { "name": "NANOS1", "type": "recommended", "evidence": [ { "id": "R4GMA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ] }, { "name": "NANOS1", "type": "synonym", "evidence": [ { "id": "XP_025007684", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007684" } ] } ], "protein_names": [ { "name": "Nanos C2HC-type zinc finger 1", "type": "synonym", "evidence": [ { "id": "R4GMA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GMA8/entry#names_and_taxonomy" } ] }, { "name": "nanos homolog 1", "type": "synonym", "evidence": [ { "id": "XP_025007684", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007684" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025007684.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007684" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NANOS1", "url": "https://www.uniprot.org/uniprotkb/R4GMA8", "locus": { "chromosome": "6", "start_pos": 30753685, "end_pos": 30752727, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002766", "url": "https://www.ensembl.org/id/ENSGALG00010002766" } ] } } ], "crossref": [ { "id": "R4GMA8", "url": "https://alphafold.ebi.ac.uk/entry/R4GMA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027980", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857342", "url": "https://www.ncbi.nlm.nih.gov/gene/100857342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857342", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QICVFCR", "url": "https://omabrowser.org/oma/group/QICVFCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "R4GMA8", "url": "https://www.orthodb.org/?gene=R4GMA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025007684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007684", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GMA8-1", "url": "https://www.uniprot.org/uniprotkb/R4GMA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAFPGGKLEPHRHLPPVERLPGARYGGRSHAACGNVFNSWNDYLGLATLITKAVRPGKGFGAEPPAVVVAAAEEEEEEEEEEEEEAAGPYFEGALDLHELELCGHHHHHGDGLLEERFADFSPFPGRGGPAAVLFDCSGEHAGRDGSAHAWGAGVVVAGRLPAHPRAAGRLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKMQAAKQLRHARTALGKKAR", "length": 254, "header": "tr|R4GMA8-1|R4GMA8_CHICK Isoform 1 of Nanos C2HC-type zinc finger 1 OS=Gallus gallus OX=9031 GN=NANOS1 PE=3 SV=3 CANONICAL=R4GMA8-1" }, "isoforms": [ { "isoform_ac": "R4GMA8-1", "url": "https://www.uniprot.org/uniprotkb/R4GMA8/entry#R4GMA8-1", "sequence": { "sequence": "MEAFPGGKLEPHRHLPPVERLPGARYGGRSHAACGNVFNSWNDYLGLATLITKAVRPGKGFGAEPPAVVVAAAEEEEEEEEEEEEEAAGPYFEGALDLHELELCGHHHHHGDGLLEERFADFSPFPGRGGPAAVLFDCSGEHAGRDGSAHAWGAGVVVAGRLPAHPRAAGRLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKMQAAKQLRHARTALGKKAR", "length": 254, "header": "tr|R4GMA8-1|R4GMA8_CHICK Isoform 1 of Nanos C2HC-type zinc finger 1 OS=Gallus gallus OX=9031 GN=NANOS1 PE=3 SV=3 CANONICAL=R4GMA8-1" }, "locus": { "chromosome": "6", "start_pos": 30753589, "end_pos": 30752828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006401.1", "url": "https://www.ensembl.org/id/ENSGALT00010006401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003956.1", "url": "https://www.ensembl.org/id/ENSGALP00010003956.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857342", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "epithelial cell migration", "id": "GO:0010631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010631", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "R4GMA8", "url": "https://www.uniprot.org/uniprotkb/R4GMA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "R4GMH7-1", "uniprot_ac": "R4GMH7", "uniprot_id": "R4GMH7_CHICK", "mass": { "chemical_mass": 19976.0, "monoisotopic_mass": 19976.0 }, "refseq": { "ac": "XP_419775", "name": "trafficking protein particle complex subunit 3-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419775" }, "gene_names": [ { "name": "TRAPPC3L", "type": "recommended", "evidence": [ { "id": "R4GMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GMH7" } ] }, { "name": "TRAPPC3L", "type": "synonym", "evidence": [ { "id": "XP_419775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419775" } ] } ], "protein_names": [ { "name": "Trafficking protein particle 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419775" } ] }, { "annotation": "May play a role in vesicular transport from endoplasmic reticulum to Golgi.", "evidence": [ { "database": "UniProtKB", "id": "R4GMH7", "url": "https://www.uniprot.org/uniprotkb/R4GMH7#function" }, { "database": "UniProtKB", "id": "ARBA00002910", "url": "https://www.uniprot.org/uniprotkb/ARBA00002910#function" }, { "database": "UniProtKB", "id": "PIRNR018293", "url": "https://www.uniprot.org/uniprotkb/PIRNR018293#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "R4GMH7", "url": "https://www.uniprot.org/uniprotkb/R4GMH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC3L", "url": "https://www.uniprot.org/uniprotkb/R4GMH7", "locus": { "chromosome": "3", "start_pos": 63541414, "end_pos": 63512513, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014830", "url": "https://www.ensembl.org/id/ENSGALG00010014830" } ] } } ], "crossref": [ { "id": "R4GMH7", "url": "https://alphafold.ebi.ac.uk/entry/R4GMH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028539", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028539", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14942", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14942", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421743", "url": "https://www.ncbi.nlm.nih.gov/gene/421743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007194", "database": 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"MSRPPGRKQDSHKISRELFVLTYGALVAQLCKDYEKDEDVNSCLDKMGYGIGVRLIDDFLAHSDVKRCRSYSETADMIAQVAFKMYLGVTPSVSCSSAAGNEFSLILDKNPLVDFVEELPAERASLCYCNLLCGVIRGALEMVHLAAEVTFLQDRLKGDAVTEIGITFLRKAEDKKAKKK", "length": 180, "header": "tr|R4GMH7-1|R4GMH7_CHICK Isoform 1 of Trafficking protein particle complex subunit OS=Gallus gallus OX=9031 GN=TRAPPC3L PE=3 SV=1 CANONICAL=R4GMH7-1" }, "locus": { "chromosome": "3", "start_pos": 63540949, "end_pos": 63521766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035684.1", "url": "https://www.ensembl.org/id/ENSGALT00010035684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020705.1", "url": "https://www.ensembl.org/id/ENSGALP00010020705.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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"https://omabrowser.org/oma/group/R4GMH7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZEX3-1", "protein_name": "Trafficking protein particle complex subunit", "gene_name": "Trappc3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRPAHKRPEYHKINKDLFVLTYGALVAQLCKDYEKDEDVNKYLDKMGYSIGTRLVEDFLARSCVRRCHSYSEIIDIIAQVAFKMYLGTTPSVTCHNSSRNEFSLILHKNPLAEFIEELPAGRSALCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDNVTEIGITFLKKVDDKKYRRKK", "length": 181 }, "evidence": [ { "id": "R4GMH7", "url": "https://omabrowser.org/oma/group/R4GMH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAY8-1", "protein_name": "Trafficking protein particle complex subunit", "gene_name": "TRAPPC3L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRPAHRRPEYRKINKDLFVLTYGALVAQLCKDYEKDEDVNKYLDTMGYGIGTRLVEDFLARSCVRRCHSYSEIADIIAQVAFKMYLGITPSVTCNNASRNEFSLILDKNPLVEFVEELPTGRSSLCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDSVTEIGITFLKKLDEKKYRRKK", "length": 181 }, "evidence": [ { "id": "R4GMH7", "url": "https://omabrowser.org/oma/group/R4GMH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KL14-1", "protein_name": "Trafficking protein particle complex subunit 3-like protein", "gene_name": "Trappc3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRPAHKRPEYHKINKDLFVLTYGALVAQLCKDYEKDEDVNKYLDKMGYNIGTRLVEDFLARSCVRRCHSYSEIINIIAQVAFKMYLGITPSVTCHNSSRNEFSLILHKNPLAEFVEELPAGRSALCYCNLLCGIIRGALEMVHLAANVTFLQDRLKGDSVTEIGITFLKKLDEKKYRRKK", "length": 181 }, "evidence": [ { "id": "R4GMH7", "url": "https://omabrowser.org/oma/group/R4GMH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T215-1", "protein_name": "Trafficking protein particle complex subunit 3-like protein", "gene_name": "TRAPPC3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRPAHRRPEYHKINKDLFVLTYGALVAQLCKDYEKDEDVNQYLDKMGYGIGTRLVEDFLARSCVGRCHSYSEIIDIIAQVAFKMYLGITPSVTCNNSSKNEFSLILEKNPLVEFVEELPAGRSSLCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDSVTEIGITFLKKRDEKKYRGKK", "length": 181 }, "evidence": [ { "id": "R4GMH7", "url": "https://omabrowser.org/oma/group/R4GMH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "R4GMH7", "url": "https://www.uniprot.org/uniprotkb/R4GMH7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "R4GMH7", "url": 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"evidence": [ { "database": "UniProtKB", "id": "R4GMH7", "url": "https://www.uniprot.org/uniprotkb/R4GMH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-R4GMH7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 180, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-R4GMH7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/R4GMH7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 90 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "V9GWB4-1", "uniprot_ac": "V9GWB4", "uniprot_id": "V9GWB4_CHICK", "mass": { "chemical_mass": 57329.0, "monoisotopic_mass": 57329.0 }, "refseq": { "ac": "XP_015128875", "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128875" }, "gene_names": [ { "name": "ZRSR2", "type": "recommended", "evidence": [ { "id": "V9GWB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ] }, { "name": "ZRSR2", "type": "synonym", "evidence": [ { "id": "XP_015128875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128875" } ] } ], "protein_names": [ { "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "type": "synonym", "evidence": [ { "id": "XP_015128875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128875" } ] }, { "name": "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2", "type": "synonym", "evidence": [ { "id": "V9GWB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWB4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128875" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZRSR2", "url": "https://www.uniprot.org/uniprotkb/V9GWB4", "locus": { "chromosome": "1", "start_pos": 121984372, "end_pos": 122005052, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001513", "url": "https://www.ensembl.org/id/ENSGALG00010001513" } ] } } ], "crossref": [ { "id": "cd12540", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12540", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428002", "url": "https://www.ncbi.nlm.nih.gov/gene/428002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDLRIME", "url": "https://omabrowser.org/oma/group/MDLRIME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "V9GWB4", "url": "https://www.orthodb.org/?gene=V9GWB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015128875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "V9GWB4-1", "url": "https://www.uniprot.org/uniprotkb/V9GWB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPMLLPESPLGKLSHQKYRAILKKEKRKKKRQALAKLRDSEATEKDESVSEEEEEELDEEEDEEEEKKLEAERQKLHEQWLLREEKAQEEFKLKKEKEEAARKRQEEEERKIKEEWEEQQRKEREVAQQKQQEKREREAAVQKMLDQAESQLENGVTWHNPEPPENIGTEKDRANCPFYIKTGSCRFGDRCSRKHNYPTSSKTLLVRGMFITFGMEQCRRDDYDTDASLEYSDEETYQQFLEFYEDVLPEFQNVGKVVQFKVSCNYEPHLRGNVYVQYQTEKDCQAALALFSGRWYAGRQLHCEFCPVTRWKTAICGLFERQKCPRGKHCNFLHVFKNPNNEFWEANRDIRVSPERTNQLSKNSERRNRSSHRDDYYGRSRRRSSPSPDHSYRRNGESERKKNRRKNKRRRRSGRSRSRERRRSRSRGRKRRGRSRSRSYSRTRSRSRSRSSSRSRSRGKKRSSSRGRNSETPKTK", "length": 478, "header": "tr|V9GWB4-1|V9GWB4_CHICK Isoform 1 of Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 OS=Gallus gallus OX=9031 GN=ZRSR2 PE=4 SV=1 CANONICAL=V9GWB4-1" }, "isoforms": [ { "isoform_ac": "V9GWB4-1", "url": "https://www.uniprot.org/uniprotkb/V9GWB4/entry#V9GWB4-1", "sequence": { "sequence": "MAAPMLLPESPLGKLSHQKYRAILKKEKRKKKRQALAKLRDSEATEKDESVSEEEEEELDEEEDEEEEKKLEAERQKLHEQWLLREEKAQEEFKLKKEKEEAARKRQEEEERKIKEEWEEQQRKEREVAQQKQQEKREREAAVQKMLDQAESQLENGVTWHNPEPPENIGTEKDRANCPFYIKTGSCRFGDRCSRKHNYPTSSKTLLVRGMFITFGMEQCRRDDYDTDASLEYSDEETYQQFLEFYEDVLPEFQNVGKVVQFKVSCNYEPHLRGNVYVQYQTEKDCQAALALFSGRWYAGRQLHCEFCPVTRWKTAICGLFERQKCPRGKHCNFLHVFKNPNNEFWEANRDIRVSPERTNQLSKNSERRNRSSHRDDYYGRSRRRSSPSPDHSYRRNGESERKKNRRKNKRRRRSGRSRSRERRRSRSRGRKRRGRSRSRSYSRTRSRSRSRSSSRSRSRGKKRSSSRGRNSETPKTK", "length": 478, "header": "tr|V9GWB4-1|V9GWB4_CHICK Isoform 1 of Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 OS=Gallus gallus OX=9031 GN=ZRSR2 PE=4 SV=1 CANONICAL=V9GWB4-1" }, "locus": { "chromosome": "1", "start_pos": 122005038, "end_pos": 121989159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003502.1", "url": "https://www.ensembl.org/id/ENSGALT00010003502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001944.1", "url": "https://www.ensembl.org/id/ENSGALP00010001944.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHQ8-1", "protein_name": "Zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2", "gene_name": "Zrsr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVVGPTAVPQKLSRKKYMALRKKEKRKKRRQELARLRDAELSQKEEEEDPLGEEKRLEEERLLEAERQRLHEEWLLREEKAQEEFRAKKRKEEAARKRKEELERKLKAEWEEQQRKEREEEEQKQQEKREREEAAQKRLDQAENELENGGTWQNPEPPTDIRVLEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDSSLEYSEEETYQQFLDFYYDVLPEFKSVGKVIQFKVSCNLEPHLRGNVYVQYQSEEDCQAAFSVFNGRWYAGRQLQCEFCPVTRWKMAICGLFEVQQCPRGKHCNFLHVFRNPNNEYREANRDIYLSPDWTSSSFAKSSERRERASHYDEYYGRSRRRRSPSPGLSYKRNGESDRKSSSNHRVKKSHKHGMKNRERHSSRSRRRKRDHSLGPWSQSRRSRHSRSRSHSQSRSRSSSRSRSCGRGRGWSHSRSHSRSRKRSRNRSRSRSRNRNRNRNRKRNQSRSWSHSHSHSRSSSRSRSPGRRRSGSRDKTTQSPKSK", "length": 541 }, "evidence": [ { "id": "V9GWB4", "url": "https://omabrowser.org/oma/group/V9GWB4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15696-1", "protein_name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "gene_name": "ZRSR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK", "length": 482 }, "evidence": [ { "id": "V9GWB4", "url": "https://omabrowser.org/oma/group/V9GWB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" }, { "name": "U2AF complex", "id": "GO:0089701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089701", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "V9GWB4", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "V9GWB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 200, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "V9GWB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V9GWB4" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 310, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "P62764-1", "uniprot_ac": "P62764", "uniprot_id": "VISL1_CHICK", "mass": { "chemical_mass": 22142.0, "monoisotopic_mass": 22142.0 }, "refseq": { "ac": "NP_990586", "name": "visinin-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" }, "gene_names": [ { "name": "VSNL1", "type": "recommended", "evidence": [ { "id": "P62764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62764" } ] }, { "name": "VSNL1", "type": "synonym", "evidence": [ { "id": "NP_990586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" } ] } ], "protein_names": [ { "name": "Visinin-like protein 1", "type": "recommended", "evidence": [ { "id": "P62764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#names_and_taxonomy" } ] }, { "name": "OZ1", "type": "synonym", "evidence": [ { "id": "NP_990586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" }, { "id": "P62764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#names_and_taxonomy" } ] }, { "name": "VILIP", "type": "synonym", "evidence": [ { "id": "NP_990586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" }, { "id": "P62764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#names_and_taxonomy" } ] }, { "name": "visinin-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_990586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01031891.1, X63530.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000067.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" } ] }, { "annotation": "Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X5A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A5#function" }, { "database": "UniProtKB", "id": "ARBA00002143", "url": "https://www.uniprot.org/uniprotkb/ARBA00002143#function" }, { "database": "UniProtKB", "id": "A0A8V0XC97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC97#function" }, { "database": "UniProtKB", "id": "A0A8V0X597", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X597#function" }, { "database": "UniProtKB", "id": "A0A8V0X5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A1#function" }, { "database": "UniProtKB", "id": "A0A8V0XEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ8#function" }, { "database": "UniProtKB", "id": "A0A8V0XF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF02#function" }, { "database": "UniProtKB", "id": "A0A8V0XFR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR0#function" }, { "database": "UniProtKB", "id": "P62764", "url": "https://www.uniprot.org/uniprotkb/P62764#function" } ] }, { "annotation": "Visinin and calretinin are induced by NeuroD in developing retinal cells", "evidence": [ { "database": "RefSeq", "id": "NP_990586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" }, { "database": "PubMed", "id": "14991711", "url": "https://glygen.org/publication/PubMed/14991711" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P62764", "url": "https://www.uniprot.org/uniprotkb/P62764" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VSNL1", "url": "https://www.uniprot.org/uniprotkb/P62764", "locus": { "chromosome": "3", "start_pos": 99939827, "end_pos": 99825974, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002364", "url": "https://www.ensembl.org/id/ENSGALG00010002364" } ] } } ], "crossref": [ { "id": "P62764", "url": "https://alphafold.ebi.ac.uk/entry/P62764", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016464", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016464", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396189", "url": "https://www.ncbi.nlm.nih.gov/gene/396189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P62764", "url": "https://www.ebi.ac.uk/intact/interactors/id:P62764*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396189", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HISRREM", "url": "https://omabrowser.org/oma/group/HISRREM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P62764", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P62764", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X597", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X597", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X597-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X597-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XC97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P62764", "url": "https://www.uniprot.org/uniprotkb/P62764", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P62764-1", "url": "https://www.uniprot.org/uniprotkb/P62764-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 191, "header": "sp|P62764-1|VISL1_CHICK Isoform 1 of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=2 CANONICAL=P62764-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X597-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0X597-1", "sequence": { "sequence": "MWTSYLLVVLPGSRQKHKLNISSSQGKPRAGDPNIYKVSIPLMSIQNKKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 186, "header": "tr|A0A8V0X597-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99861683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005362.1", "url": "https://www.ensembl.org/id/ENSGALT00010005362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003201.1", "url": "https://www.ensembl.org/id/ENSGALP00010003201.1" } ] } }, { "isoform_ac": "A0A8V0X5A1-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0X5A1-1", "sequence": { "sequence": "MVRQSRLWCCWEKEPHGVGGVTSHCQQQGQGCAGLPTFQHLSIPAPPFLLLFSACWSGVALLTFLAVSPCSYENDLDLRMQILFNRHTNMVSFATQLPKSFTRQAVCSGFVFQFWNSNFMPGCTVHSCVFLCVVSEPRTASGVRFCKFCRFLWISRGRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 349, "header": "tr|A0A8V0X5A1-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99828534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005367.1", "url": "https://www.ensembl.org/id/ENSGALT00010005367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003206.1", "url": "https://www.ensembl.org/id/ENSGALP00010003206.1" } ] } }, { "isoform_ac": "A0A8V0X5A5-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0X5A5-1", "sequence": { "sequence": "MPGCTVHSCVFLCVVSEPRTASGVRFCKFCRFLWISRGRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 230, "header": "tr|A0A8V0X5A5-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99828891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005372.1", "url": "https://www.ensembl.org/id/ENSGALT00010005372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003211.1", "url": "https://www.ensembl.org/id/ENSGALP00010003211.1" } ] } }, { "isoform_ac": "A0A8V0XC97-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0XC97-1", "sequence": { "sequence": "MQLGRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 196, "header": "tr|A0A8V0XC97-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99855551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005364.1", "url": "https://www.ensembl.org/id/ENSGALT00010005364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003203.1", "url": "https://www.ensembl.org/id/ENSGALP00010003203.1" } ] } }, { "isoform_ac": "A0A8V0XEZ8-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0XEZ8-1", "sequence": { "sequence": "MPQCLRGVAAQAPYPSSGRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 210, "header": "tr|A0A8V0XEZ8-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99832901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005365.1", "url": "https://www.ensembl.org/id/ENSGALT00010005365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003204.1", "url": "https://www.ensembl.org/id/ENSGALP00010003204.1" } ] } }, { "isoform_ac": "A0A8V0XF02-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0XF02-1", "sequence": { "sequence": "MPMSYQRDFQEKDSVDIPECRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 212, "header": "tr|A0A8V0XF02-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99859049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005370.1", "url": "https://www.ensembl.org/id/ENSGALT00010005370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003209.1", "url": "https://www.ensembl.org/id/ENSGALP00010003209.1" } ] } }, { "isoform_ac": "A0A8V0XFR0-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0XFR0-1", "sequence": { "sequence": "MYPPPPPHLGRSVSLPPSSCSPLLSPILSSALCPPPQWGWVFLREGSAILCNCSPPQRSPVEALRSRDGARCLSRAGRTSPSPGTGRMGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 278, "header": "tr|A0A8V0XFR0-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99827045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005368.1", "url": "https://www.ensembl.org/id/ENSGALT00010005368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003207.1", "url": "https://www.ensembl.org/id/ENSGALP00010003207.1" } ] } }, { "isoform_ac": "A0A8V0XFR7-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#A0A8V0XFR7-1", "sequence": { "sequence": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKNNPSAVVKGPGGCWRCPRRPHSLGAARASTPSPARH", "length": 90, "header": "tr|A0A8V0XFR7-1|VISL1_CHICK Computationally mapped isoform of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=1 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99939195, "end_pos": 99859625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005374.1", "url": "https://www.ensembl.org/id/ENSGALT00010005374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003213.1", "url": "https://www.ensembl.org/id/ENSGALP00010003213.1" } ] } }, { "isoform_ac": "P62764-1", "url": "https://www.uniprot.org/uniprotkb/P62764/entry#P62764-1", "sequence": { "sequence": "MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK", "length": 191, "header": "sp|P62764-1|VISL1_CHICK Isoform 1 of Visinin-like protein 1 OS=Gallus gallus OX=9031 GN=VSNL1 PE=2 SV=2 CANONICAL=P62764-1" }, "locus": { "chromosome": "3", "start_pos": 99901062, "end_pos": 99859625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005373.1", "url": "https://www.ensembl.org/id/ENSGALT00010005373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003212.1", "url": "https://www.ensembl.org/id/ENSGALP00010003212.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "VILIP, a cognate protein of the retinal calcium binding proteins visinin and recoverin, is expressed in the developing chicken brain.", "journal": "Brain Res. Mol. Brain Res.", "date": "1992", "authors": "Lenz S E, Henschel Y, Zopf D, Voss B, Gundelfinger E D", "evidence": [ { "database": "UniProtKB", "id": "P62764", "url": "https://www.uniprot.org/uniprotkb/P62764" } ], "reference": [ { "type": "PubMed", "id": "1359372", "url": "https://glygen.org/publication/PubMed/1359372" } ] }, { "title": "NeuroD induces the expression of visinin and calretinin by proliferating cells derived from toxin-damaged chicken retina.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2004-03", "authors": "Fischer Andy J, Wang Shu-Zhen, Reh Thomas A", "evidence": [ { "database": "RefSeq", "id": "NP_990586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990586" } ], "reference": [ { "type": "PubMed", "id": "14991711", "url": "https://glygen.org/publication/PubMed/14991711" } ] } ], "pathway": [ { "id": "gga:396189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396189", "resource": 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"ECO_0000255", "start_pos": 84, "end_pos": 84, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1P3C0-1", "uniprot_ac": "F1P3C0", "uniprot_id": "F1P3C0_CHICK", "mass": { "chemical_mass": 40400.0, "monoisotopic_mass": 40400.0 }, "refseq": { "ac": "NP_001006276", "name": "replication factor C subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" }, "gene_names": [ { "name": "RFC3", "type": "recommended", "evidence": [ { "id": "F1P3C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C0" } ] }, { "name": "RFC3", "type": "synonym", "evidence": [ { "id": "NP_001006276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" } ] } ], "protein_names": [ { "name": "Replication factor C subunit 3", "type": "recommended", "evidence": [ { "id": "F1P3C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#names_and_taxonomy" } ] }, { "name": "Activator 1 38 kDa subunit", "type": "synonym", "evidence": [ { "id": "F1P3C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#names_and_taxonomy" } ] }, { "name": "Activator 1 subunit 3", "type": "synonym", "evidence": [ { "id": "F1P3C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#names_and_taxonomy" } ] }, { "name": "Replication factor C 38 kDa subunit", "type": "synonym", "evidence": [ { "id": "F1P3C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#names_and_taxonomy" } ] }, { "name": "replication factor C (activator 1) 3, 38kDa", "type": "synonym", "evidence": [ { "id": "NP_001006276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" } ] }, { "name": "replication factor C subunit 3", "type": "synonym", "evidence": [ { "id": "NP_001006276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720394.1, HAEL01007039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000027.1. On Sep 23, 2021 this sequence version replaced NP_001006276.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" } ] }, { "annotation": "RFC3 shows higher fold expression primarily in EGK.X blastoderms and secondarily in primordial germ cells compared to chicken embryonic fibroblasts. 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Pathway" ] }, { "id": "LKADIMH", "url": "https://omabrowser.org/oma/group/LKADIMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLL1", "url": "https://www.orthodb.org/?gene=A0A8V0XLL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSX1", "url": "https://www.orthodb.org/?gene=A0A8V0XSX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3C0", "url": "https://www.orthodb.org/?gene=F1P3C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11669:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11669:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13177", "database": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69091", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69091", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XLL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3C0", "url": "https://www.uniprot.org/uniprotkb/F1P3C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3C0-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLWVDKYRPSALSRLDFHREQAAQLRSLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITAPSKKKIEISTIASNYHLEVNPSDAGNNDRVVIQELLKTVAQSQQLETSTQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMATCRLILCCNSISKIIGPIQSRCLSVRVPAPSIEDICHVLSSVCKKEGLNLPPELAQRLAEKSGRNLRKALLMCESCRVQQYPFSADQDIPEMDWEIYLRETANAIVSQQSPQRLLEVRGRLYELLTHCIPPEIIMKGLLTELLNNCDGQLKGEVAQMAAFYEHRLQLGSKAIYHLEAFVAKFMAIYKKFMEDGLDDMMF", "length": 356, "header": "tr|F1P3C0-1|F1P3C0_CHICK Isoform 1 of Replication factor C subunit 3 OS=Gallus gallus OX=9031 GN=RFC3 PE=1 SV=1 CANONICAL=F1P3C0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XLL1-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#A0A8V0XLL1-1", "sequence": { "sequence": "MVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITAPSKKKIEISTIASNYHLEVNPSDAGNNDRVVIQELLKTVAQSQQLETSTQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMATCRLILCCNSISKIIGPIQSRCLSVRVPAPSIEDICHVLSSVCKKEGLNLPPELAQRLAEKSGRNLRKALLMCESCRVQQYPFSADQDIPEMDWEIYLRETANAIVSQQSPQRLLEVRGRLYELLTHCIPPEIIMKGLLTELLNNCDGQLKGEVAQMAAFYEHRLQLGSKAIYHLEAFVAKFMAIYKKFMEDGLDDMMF", "length": 328, "header": "tr|A0A8V0XLL1-1|F1P3C0_CHICK Computationally mapped isoform of Replication factor C subunit 3 OS=Gallus gallus OX=9031 GN=RFC3 PE=1 SV=1 CANONICAL=F1P3C0-1" }, "locus": { "chromosome": "1", "start_pos": 173748478, "end_pos": 173729837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015565.1", "url": "https://www.ensembl.org/id/ENSGALT00010015565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009069.1", "url": "https://www.ensembl.org/id/ENSGALP00010009069.1" } ] } }, { "isoform_ac": "A0A8V0XSX1-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#A0A8V0XSX1-1", "sequence": { "sequence": "MELSVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITAPSKKKIEISTIASNYHLEVNPSDAGNNDRVVIQELLKTVAQSQQLETSTQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMATCRLILCCNSISKIIGPIQSRCLSVRVPAPSIEDICHVLSSVCKKEGLNLPPELAQRLAEKSGRNLRKALLMCESCRVQQYPFSADQDIPEMDWEIYLRETANAIVSQQSPQRLLEVRGRLYELLTHCIPPEIIMKGLLTELLNNCDGQLKGEVAQMAAFYEHRLQLGSKAIYHLEAFVAKFMAIYKKFMEDGLDDMMF", "length": 331, "header": "tr|A0A8V0XSX1-1|F1P3C0_CHICK Computationally mapped isoform of Replication factor C subunit 3 OS=Gallus gallus OX=9031 GN=RFC3 PE=1 SV=1 CANONICAL=F1P3C0-1" }, "locus": { "chromosome": "1", "start_pos": 173741444, "end_pos": 173729837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015559.1", "url": "https://www.ensembl.org/id/ENSGALT00010015559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009066.1", "url": "https://www.ensembl.org/id/ENSGALP00010009066.1" } ] } }, { "isoform_ac": "F1P3C0-1", "url": "https://www.uniprot.org/uniprotkb/F1P3C0/entry#F1P3C0-1", "sequence": { "sequence": "MSLWVDKYRPSALSRLDFHREQAAQLRSLVQCGDFPHLLVYGPSGAGKKTRIMCLLRELYGAGVEKLRIEHQSITAPSKKKIEISTIASNYHLEVNPSDAGNNDRVVIQELLKTVAQSQQLETSTQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMATCRLILCCNSISKIIGPIQSRCLSVRVPAPSIEDICHVLSSVCKKEGLNLPPELAQRLAEKSGRNLRKALLMCESCRVQQYPFSADQDIPEMDWEIYLRETANAIVSQQSPQRLLEVRGRLYELLTHCIPPEIIMKGLLTELLNNCDGQLKGEVAQMAAFYEHRLQLGSKAIYHLEAFVAKFMAIYKKFMEDGLDDMMF", "length": 356, "header": "tr|F1P3C0-1|F1P3C0_CHICK Isoform 1 of Replication factor C subunit 3 OS=Gallus gallus OX=9031 GN=RFC3 PE=1 SV=1 CANONICAL=F1P3C0-1" }, "locus": { "chromosome": "1", "start_pos": 173741786, "end_pos": 173729837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015561.1", "url": "https://www.ensembl.org/id/ENSGALT00010015561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009067.1", "url": "https://www.ensembl.org/id/ENSGALP00010009067.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken blastoderms and primordial germ cells possess a higher expression of DNA repair genes and lower expression of apoptosis genes to preserve their genome stability.", "journal": "Scientific reports", "date": "2022-01-07", "authors": "Rengaraj Deivendran, Won Sohyoung, Jung Kyung Min, Woo Seung Je, Lee Haerang, Kim Young Min, Kim Heebal, Han Jae Yong", "evidence": [ { "database": "RefSeq", "id": "NP_001006276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006276" } ], "reference": [ { "type": "PubMed", "id": "34997179", "url": "https://glygen.org/publication/PubMed/34997179" } ] } ], "pathway": [ { "id": "gga:418907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418907", "resource": "KEGG Pathway" }, { "id": "R-GGA-110312", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110312", "resource": "Reactome", "description": "Translesion synthesis by REV1" }, { "id": "R-GGA-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-GGA-110320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110320", "resource": "Reactome", "description": "Translesion Synthesis by POLH" }, { "id": "R-GGA-174411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174411", "resource": "Reactome", "description": "Polymerase switching on the C-strand of the telomere" }, { "id": "R-GGA-176187", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176187", "resource": "Reactome", "description": "Activation of ATR in response to replication stress" }, { "id": "R-GGA-5651801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5651801", "resource": "Reactome", "description": "PCNA-Dependent Long Patch Base Excision Repair" }, { "id": "R-GGA-5655862", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5655862", "resource": "Reactome", "description": "Translesion synthesis by POLK" }, { "id": "R-GGA-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-GGA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" }, { "id": "R-GGA-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-GGA-5696397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696397", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in GG-NER" }, { "id": "R-GGA-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-69091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69091", "resource": "Reactome", "description": "Polymerase switching" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480UUW0-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLWVDKYRPCSLGQLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQKDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLSLPSQLARKLAEKSCRNLRKALLMCEACRVQQYPFTVDQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMIF", "length": 356 }, "evidence": [ { "id": "F1P3C0", "url": "https://omabrowser.org/oma/group/F1P3C0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P38251-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCLD", "length": 354 }, "evidence": [ { "id": "F1P3C0", "url": "https://omabrowser.org/oma/group/F1P3C0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF", "length": 356 }, "evidence": [ { "id": "F1P3C0", "url": "https://omabrowser.org/oma/group/F1P3C0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2TBV1-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLWVDKYRPCSLGQLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQKDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPPQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMIF", "length": 356 }, "evidence": [ { "id": "F1P3C0", "url": "https://omabrowser.org/oma/group/F1P3C0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54BN3-1", "protein_name": "Probable replication factor C subunit 3", "gene_name": "rfc3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLWIDKYKPTSLDKMDYHNDISINLKNMIKSGDFPHLLVYGPSGAGKKTRILAVLQEIYGPNALKLKIDHRTFKHPTSSKNIQITTISSHYHIEINPGEAGSYDRVVIQTIIKEIAQSPPIDSGSLGAFKIVILNEVDKLSKDAQHALRRTMEKYATFCRLILCCDSTAKVIDPIKSRCLGIRVPAPSQEEIEKVLAKVATAEKFDLPSKLAVNVAKQSGGNLRYALMLLESQKAKQYPFQSTELPLLDWENYISQIVKDCFEEQSPARLSIVRGKLYELLGHCIPPELIFKTLLLEIFKKLDHNMKFEIIHWASYYEHRSQIGSKPIFHLEAFIAKFMSVYKKYNQ", "length": 347 }, "evidence": [ { "id": "F1P3C0", "url": "https://omabrowser.org/oma/group/F1P3C0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5M830-1", "protein_name": "Replication factor C subunit 3", "gene_name": "Rfc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P62758-1", "uniprot_ac": "P62758", "uniprot_id": "NCALD_CHICK", "mass": { "chemical_mass": 22261.0, "monoisotopic_mass": 22261.0 }, "refseq": { "ac": "NP_990474", "name": "neurocalcin-delta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474" }, "gene_names": [ { "name": "NCALD", "type": "recommended", "evidence": [ { "id": "P62758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62758" } ] }, { "name": "NCALD", "type": "synonym", "evidence": [ { "id": "NP_990474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474" } ] }, { "name": "neurocalcin-delta", "type": "synonym", "evidence": [ { "id": "NP_990474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474" } ] } ], "protein_names": [ { "name": "Neurocalcin-delta", "type": "recommended", "evidence": [ { "id": "P62758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62758/entry#names_and_taxonomy" } ] }, { "name": "neurocalcin-delta", "type": "synonym", "evidence": [ { "id": "NP_990474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01017846.1, HAEK01079772.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474" } ] }, { "annotation": "May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y6K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K0#function" }, { "database": "UniProtKB", "id": "ARBA00037437", "url": "https://www.uniprot.org/uniprotkb/ARBA00037437#function" }, { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCALD", "url": "https://www.uniprot.org/uniprotkb/P62758", "locus": { "chromosome": "2", "start_pos": 128462961, "end_pos": 128512861, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011885", "url": "https://www.ensembl.org/id/ENSGALG00010011885" } ] } } ], "crossref": [ { "id": "P62758", "url": "https://alphafold.ebi.ac.uk/entry/P62758", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000032518", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000032518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396048", "url": "https://www.ncbi.nlm.nih.gov/gene/396048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P62758", "url": "https://www.ebi.ac.uk/intact/interactors/id:P62758*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396048", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396048", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGCVCMK", "url": "https://omabrowser.org/oma/group/MGCVCMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6K0", "url": "https://www.orthodb.org/?gene=A0A8V0Y6K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P62758", "url": "https://www.orthodb.org/?gene=P62758", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P62758", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P62758", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P62758-1", "url": "https://www.uniprot.org/uniprotkb/P62758-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193, "header": "sp|P62758-1|NCALD_CHICK Isoform 1 of Neurocalcin-delta OS=Gallus gallus OX=9031 GN=NCALD PE=2 SV=2 CANONICAL=P62758-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6K0-1", "url": "https://www.uniprot.org/uniprotkb/P62758/entry#A0A8V0Y6K0-1", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGRVLCCLWDLEVCEDQKECSEAHIQVFNFPHKLFFFLSVH", "length": 201, "header": "tr|A0A8V0Y6K0-1|NCALD_CHICK Computationally mapped isoform of Neurocalcin-delta OS=Gallus gallus OX=9031 GN=NCALD PE=2 SV=1 CANONICAL=P62758-1" }, "locus": { "chromosome": "2", "start_pos": 128479289, "end_pos": 128472679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028405.1", "url": "https://www.ensembl.org/id/ENSGALT00010028405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016285.1", "url": "https://www.ensembl.org/id/ENSGALP00010016285.1" } ] } }, { "isoform_ac": "P62758-1", "url": "https://www.uniprot.org/uniprotkb/P62758/entry#P62758-1", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193, "header": "sp|P62758-1|NCALD_CHICK Isoform 1 of Neurocalcin-delta OS=Gallus gallus OX=9031 GN=NCALD PE=2 SV=2 CANONICAL=P62758-1" }, "locus": { "chromosome": "2", "start_pos": 128479289, "end_pos": 128471832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028410.1", "url": "https://www.ensembl.org/id/ENSGALT00010028410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016288.1", "url": "https://www.ensembl.org/id/ENSGALP00010016288.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396048", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A9JTH1-1", "protein_name": "Neurocalcin-delta A", "gene_name": "ncalda", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGNLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIKGAKTDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z561-1", "protein_name": "Neurocalcin-delta", "gene_name": "NCALD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P42325-1", "protein_name": "Neurocalcin homolog", "gene_name": "Nca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH", "length": 190 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P61601-1", "protein_name": "Neurocalcin-delta", "gene_name": "NCALD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61602-1", "protein_name": "Neurocalcin-delta", "gene_name": "NCALD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PQN0-1", "protein_name": "Neurocalcin-delta", "gene_name": "Ncald", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91X97-1", "protein_name": "Neurocalcin-delta", "gene_name": "Ncald", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "length": 193 }, "evidence": [ { "id": "P62758", "url": "https://omabrowser.org/oma/group/P62758/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "P62758", "url": "https://www.uniprot.org/uniprotkb/P62758" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P62758-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 193, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P62758-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P62758" } ], "lectin_list": 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The reference sequence was derived from JAENSK010000012.1. On Jun 23, 2012 this sequence version replaced XP_425425.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. 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"https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9009391", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9009391", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9717207", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9717207", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001254740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3R0-1", "url": "https://www.uniprot.org/uniprotkb/F1P3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGASSESKESARRSRELEKKLQEDAEREARTVKLLLLGAGESGKSTIVKQMKIIHKDGFTYQERMEFRPIIYSNTVQSILSIVKAMTKLGISYENPARIEDERKLCDMETNLDDSNMSSELVELIKQLWKDGGIQACFARASEYELNDSAAYYLNDLDRLAMPDYVPSEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDKEVNRMHESLQLFNSICNHRCFATTSIVLFLNKKDLFQEKIAKVHLNICFPEYNGLNTFEDAGNYIKKQFLDLNIRKEDKEIYCHLTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354, "header": "tr|F1P3R0-1|F1P3R0_CHICK Isoform 1 of G protein subunit alpha transducin 3 OS=Gallus gallus OX=9031 GN=GNAT3 PE=4 SV=2 CANONICAL=F1P3R0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6L3-1", "url": "https://www.uniprot.org/uniprotkb/F1P3R0/entry#A0A8V0Y6L3-1", "sequence": { "sequence": "MKLEMNRGAGESGKSTIVKQMKIIHKDGFTYQERMEFRPIIYSNTVQSILSIVKAMTKLGISYENPARIEDERKLCDMETNLDDSNMSSELVELIKQLWKDGGIQACFARASEYELNDSAAYYLNDLDRLAMPDYVPSEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDKEVNRMHESLQLFNSICNHRCFATTSIVLFLNKKDLFQEKIAKVHLNICFPEYNGLNTFEDAGNYIKKQFLDLNIRKEDKEIYCHLTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 322, "header": "tr|A0A8V0Y6L3-1|F1P3R0_CHICK Computationally mapped isoform of G protein subunit alpha transducin 3 OS=Gallus gallus OX=9031 GN=GNAT3 PE=4 SV=1 CANONICAL=F1P3R0-1" }, "locus": { "chromosome": "1", "start_pos": 11500798, "end_pos": 11480449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020103.1", "url": "https://www.ensembl.org/id/ENSGALT00010020103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011651.1", "url": "https://www.ensembl.org/id/ENSGALP00010011651.1" } ] } }, { "isoform_ac": "F1P3R0-1", "url": "https://www.uniprot.org/uniprotkb/F1P3R0/entry#F1P3R0-1", "sequence": { "sequence": "MGGGASSESKESARRSRELEKKLQEDAEREARTVKLLLLGAGESGKSTIVKQMKIIHKDGFTYQERMEFRPIIYSNTVQSILSIVKAMTKLGISYENPARIEDERKLCDMETNLDDSNMSSELVELIKQLWKDGGIQACFARASEYELNDSAAYYLNDLDRLAMPDYVPSEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDKEVNRMHESLQLFNSICNHRCFATTSIVLFLNKKDLFQEKIAKVHLNICFPEYNGLNTFEDAGNYIKKQFLDLNIRKEDKEIYCHLTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354, "header": "tr|F1P3R0-1|F1P3R0_CHICK Isoform 1 of G protein subunit alpha transducin 3 OS=Gallus gallus OX=9031 GN=GNAT3 PE=4 SV=2 CANONICAL=F1P3R0-1" }, "locus": { "chromosome": "1", "start_pos": 11500798, "end_pos": 11475317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020109.1", "url": "https://www.ensembl.org/id/ENSGALT00010020109.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011657.1", "url": "https://www.ensembl.org/id/ENSGALP00010011657.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Distribution of \u03b1-transducin and \u03b1-gustducin immunoreactive cells in the chicken (Gallus domesticus) gastrointestinal tract.", "journal": "Poultry science", "date": "2016-07-01", "authors": "Mazzoni M, Bombardi C, Vallorani C, Sirri F, De Giorgio R, Caio G, Grandis A, Sternini C, Clavenzani P", "evidence": [ { "database": "RefSeq", "id": "NP_001254740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001254740" } ], "reference": [ { "type": "PubMed", "id": "26957624", "url": "https://glygen.org/publication/PubMed/26957624" } ] } ], "pathway": [ { "id": "gga:427851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427851", "resource": "KEGG Pathway" }, { "id": "R-GGA-170670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170670", "resource": "Reactome", "description": "Adenylate cyclase inhibitory pathway" }, { "id": "R-GGA-392170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392170", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 12" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-GGA-9009391", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9009391", "resource": "Reactome", "description": "Extra-nuclear estrogen signaling" }, { "id": "R-GGA-9717207", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9717207", "resource": "Reactome", "description": "Sensory perception of sweet, bitter, and umami (glutamate) taste" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IP13-1", "protein_name": "Guanine nucleotide-binding protein G(T) subunit alpha-3 isoform X2", "gene_name": "Gnat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDKQQLLAMASTLEDGDMTPQLVEVIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRITAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1SFP2-1", "protein_name": "G protein subunit alpha transducin 3", "gene_name": "GNAT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSSISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMATLGIDYANPRSAEDQRQLHVMANTLEDGRLTPELAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRIAAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCASLSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8MTJ3-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMTPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C7Q4-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGIGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMATLEIDYVNPRSAEDQQQLCAMANTLEDGSMTPELAEIIKRLWRDPGVQACFERASEYQLNDSAAYYLNDLDRIAAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P29348-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "Gnat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYVNPRSREDQQLLLSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3I2-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "Gnat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSGISSESKESARRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMATLGIDYVNPRSREDQEQLHSMANTLEDGDMTPQLAEIIKRLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "length": 354 }, "evidence": [ { "id": "F1P3R0", "url": "https://omabrowser.org/oma/group/F1P3R0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "phototransduction, visible light", "id": "GO:0007603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007603", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" }, { "name": "sensory perception of sweet taste", "id": "GO:0050916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050916", "evidence": [ { "database": "UniProtKB", "id": "F1P3R0", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, 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"A0A8V0Y6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L3" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 15, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 15, "end_pos": 15, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3R0#function" }, { "id": "F1P3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 181, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 181, "end_pos": 181, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3R0#function" }, { "id": "F1P3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3R0" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 47, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 47, "end_pos": 47, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 149, "end_pos": 151 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1P4R3-1", "uniprot_ac": "F1P4R3", "uniprot_id": "F1P4R3_CHICK", "mass": { "chemical_mass": 32430.0, "monoisotopic_mass": 32430.0 }, "refseq": { "ac": "XP_004938569", "name": "four and a half LIM domains protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938569" }, "gene_names": [ { "name": "FHL2", "type": "recommended", "evidence": [ { "id": "F1P4R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ] }, { "name": "FHL2", "type": "synonym", "evidence": [ { "id": "XP_004938569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938569" } ] } ], "protein_names": [ { "name": "Four and a half LIM domains 2", "type": "synonym", "evidence": [ { "id": "F1P4R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4R3/entry#names_and_taxonomy" } ] }, { "name": "four and a half LIM domains protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938569" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938569" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FHL2", "url": "https://www.uniprot.org/uniprotkb/F1P4R3", "locus": { "chromosome": "1", "start_pos": 135254050, "end_pos": 135293985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013232", "url": "https://www.ensembl.org/id/ENSGALG00010013232" } ] } } ], "crossref": [ { "id": "F1P4R3", "url": "https://alphafold.ebi.ac.uk/entry/F1P4R3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016797", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016797", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09422", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09422", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09426", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09426", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09431", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09431", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418726", "url": "https://www.ncbi.nlm.nih.gov/gene/418726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418726", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYEQQYA", "url": "https://omabrowser.org/oma/group/CYEQQYA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCT4", "url": "https://www.orthodb.org/?gene=A0A8V0YCT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR13", "url": "https://www.orthodb.org/?gene=A0A8V0YR13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4R3", "url": "https://www.orthodb.org/?gene=F1P4R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004938569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4R3-1", "url": "https://www.uniprot.org/uniprotkb/F1P4R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTERFDCHYCKESLFGKKYILREDSPYCVKCYENLYSNTCEECKKPIGADCKDLSYKDRHWHETCFHCFQCKNSLVDKPFAAKEEHLLCTDCYSNEYSSKCNECKKTIMPGTRKMEYKGNSWHETCFICYRCQQPIGTKSFIPKDNQNFCVPCYEKQFAMQCVQCKKAITTGGVTYREQPWHKECFVCTGCKKQLSGQRFTSRDEFAYCLSCFCNLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPECGKDI", "length": 279, "header": "tr|F1P4R3-1|F1P4R3_CHICK Isoform 1 of Four and a half LIM domains 2 OS=Gallus gallus OX=9031 GN=FHL2 PE=1 SV=2 CANONICAL=F1P4R3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCT4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4R3/entry#A0A8V0YCT4-1", "sequence": { "sequence": "MTERFDCHYCKESLFGKKYILREDSPYCVKCYENLYSNTCEECKKPIGADCKDRHWHETCFHCFQCKNSLVDKPFAAKEEHLLCTDCYSNEYSSKCNECKKTIMPGTRKMEYKGNSWHETCFICYRCQQPIGTKSFIPKDNQNFCVPCYEKQFAMQCVQCKKAITTGGVTYREQPWHKECFVCTGCKKQLSGQRFTSRDEFAYCLSCFCNLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPECGKDI", "length": 274, "header": "tr|A0A8V0YCT4-1|F1P4R3_CHICK Computationally mapped isoform of Four and a half LIM domains 2 OS=Gallus gallus OX=9031 GN=FHL2 PE=1 SV=1 CANONICAL=F1P4R3-1" }, "locus": { "chromosome": "1", "start_pos": 135268532, "end_pos": 135255227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031787.1", "url": "https://www.ensembl.org/id/ENSGALT00010031787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018607.1", "url": "https://www.ensembl.org/id/ENSGALP00010018607.1" } ] } }, { "isoform_ac": "A0A8V0YR13-1", "url": "https://www.uniprot.org/uniprotkb/F1P4R3/entry#A0A8V0YR13-1", "sequence": { "sequence": "MTERFDCHYCKESLFGKKYILREDSPYCVKCYENLYSNTCEECKKPIGADCKMKKSSKLRKLLQVF", "length": 66, "header": "tr|A0A8V0YR13-1|F1P4R3_CHICK Computationally mapped isoform of Four and a half LIM domains 2 OS=Gallus gallus OX=9031 GN=FHL2 PE=1 SV=1 CANONICAL=F1P4R3-1" }, "locus": { "chromosome": "1", "start_pos": 135268532, "end_pos": 135266864, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031782.1", "url": "https://www.ensembl.org/id/ENSGALT00010031782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018603.1", "url": "https://www.ensembl.org/id/ENSGALP00010018603.1" } ] } }, { "isoform_ac": "F1P4R3-1", "url": "https://www.uniprot.org/uniprotkb/F1P4R3/entry#F1P4R3-1", "sequence": { "sequence": "MTERFDCHYCKESLFGKKYILREDSPYCVKCYENLYSNTCEECKKPIGADCKDLSYKDRHWHETCFHCFQCKNSLVDKPFAAKEEHLLCTDCYSNEYSSKCNECKKTIMPGTRKMEYKGNSWHETCFICYRCQQPIGTKSFIPKDNQNFCVPCYEKQFAMQCVQCKKAITTGGVTYREQPWHKECFVCTGCKKQLSGQRFTSRDEFAYCLSCFCNLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPECGKDI", "length": 279, "header": "tr|F1P4R3-1|F1P4R3_CHICK Isoform 1 of Four and a half LIM domains 2 OS=Gallus gallus OX=9031 GN=FHL2 PE=1 SV=2 CANONICAL=F1P4R3-1" }, "locus": { "chromosome": "1", "start_pos": 135268532, "end_pos": 135255227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031790.1", "url": "https://www.ensembl.org/id/ENSGALT00010031790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018609.1", "url": "https://www.ensembl.org/id/ENSGALP00010018609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418726", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AH53-1", "protein_name": "Four and a half LIM domains 2", "gene_name": "FHL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTERFDCHHCENSLFGRKYVLREEQPYCVGCFEALFASTCEECGKLIGCDCKDLSYKDRHWHEACFHCSRCRSSLVDKPFAAKEDQVLCTDCYSQEYSSRCQECRKAIMPGTRKMEYKGSSWHETCFTCHRCQQPIGTKSFIPKDGQNFCVPCYEKQHALQCIQCKKPITSGGVTYREQPWHRECFVCTACKKPLSGQRFTSRDEFAYCLGCFCDLYAKKCTGCANPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFVTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H5P2-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "Fhl2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTERFDCYHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQGCKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKEDQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCELYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70433-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "Fhl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14192-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KI95-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTERFDCHHCEDSLFGRKYVLREEQPYCVACFEALFASTCEECGKLIGCDCKDLSYKDRHWHEACFHCSRCRGSLVDKPFAAKEDQLLCTDCYSQEYSSRCQECKKSIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDSENFCVPCYERQYALQCVQCKKPITTGGVTYREQPWHRECFVCTACKKPLSGQRFTSRDEFAYCLGCFCDLYAKKCAGCANPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55DS4-1", "protein_name": "LIM domain-containing protein G", "gene_name": "limG", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTETNNNLCIGCNKPFKSTDNIKTSNFKKYHEQCFSQDLNCSKCSGPIIASAEHKQVLGKIYHSKCFTCASCSKVLSDNDFSEISGIPCCKSCFTEIKFNPNFAISKFGSASAITQNDEKTKEKFEMKTNLYNNLQKGKDICTWCRNQIQADPDNEAVSFGGNIYHSNCFTCSKCSSSIGKNQFVTGSDGSAICKSCSDKSKQVNCFACKKPIDSTFTVVSGNKYHPNCFVCSQCKGSLEKGYIEKDGPVCGKCAATFTQPQTRTFAYSNGKGARPNGRW", "length": 281 }, "evidence": [ { "id": "F1P4R3", "url": "https://omabrowser.org/oma/group/F1P4R3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "negative regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070885", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "response to hormone", "id": "GO:0009725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009725", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "heart trabecula formation", "id": "GO:0060347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060347", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "ventricular cardiac muscle cell development", "id": "GO:0055015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055015", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" }, { "name": "atrial cardiac muscle cell development", "id": "GO:0055014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055014", "evidence": [ { "database": "UniProtKB", "id": "F1P4R3", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4R3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 279, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4R3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4R3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4R3" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 98, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4T6-1", "uniprot_ac": "F1P4T6", "uniprot_id": "F1P4T6_CHICK", "mass": { "chemical_mass": 91810.0, "monoisotopic_mass": 91810.0 }, "refseq": { "ac": "XP_004935352", "name": "CSC1-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935352" }, "gene_names": [ { "name": "TMEM63A", "type": "recommended", "evidence": [ { "id": "F1P4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ] }, { "name": "TMEM63A", "type": "synonym", "evidence": [ { "id": "XP_004935352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935352" } ] } ], "protein_names": [ { "name": "CSC1-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_004935352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935352" } ] }, { "name": "Transmembrane protein 63A", "type": "synonym", "evidence": [ { "id": "F1P4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935352" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM63A", "url": "https://www.uniprot.org/uniprotkb/F1P4T6", "locus": { "chromosome": "3", "start_pos": 16908659, "end_pos": 16879681, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015917", "url": "https://www.ensembl.org/id/ENSGALG00010015917" } ] } } ], "crossref": [ { "id": "F1P4T6", "url": "https://alphafold.ebi.ac.uk/entry/F1P4T6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009275", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421319", "url": "https://www.ncbi.nlm.nih.gov/gene/421319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421319", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421319", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPTQVIW", "url": "https://omabrowser.org/oma/group/DPTQVIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0L2", "url": "https://www.orthodb.org/?gene=A0A8V0Z0L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4T6", "url": "https://www.orthodb.org/?gene=F1P4T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13018:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13018:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004935352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4T6-1", "url": "https://www.uniprot.org/uniprotkb/F1P4T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPVFFLGIGRSHLAYSWNRSGLFNSTNETYCYSTARGSTVLQGVTFGGIPTVLLLDVTCFFILILLFSIIRKRFWDYGRVALVSEAECGVRYTHSSASSSAPEVLEYDSGFCSWMAAAFRMHDDEIHDRCGEDAIHYLTFQRHIICLLVAVSILSVGVILPVNLSGDLLVKDPYSFGRTTIQNLETGNNLLWLHTFFAVVYLILTVVFMSHHMKTVTYKEENIVKCTLFITGLPKNAKQEAIEGHFIAAYPTCTVLEVQLCYDVARLIHLFRKRNEAEKSLDYYKRLYEKHGKRAKINPKPCGQFCCCEMRGCKREDAVDYYTRVTNELIEEFSKEEQAVQNKPLGMAFVTFQEKSMATYILKDFNACKCRSIKCKGEPQPSSYSKELRVTNWEVKYATYPENICWNNLSVCGLNWWVRWWCINLSLLILLFFLTTPSIIISTMDKFNVTKPIHYLNNPIISQFFPTLLLWSFSALLPTIVYYSTLLESHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFDRESSDSAIRLECVFLPDQGAFFVNYVIASAFVGNGMELLRLPGLILYTIRMIMAKSSAERKNIKQQQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYMLLKHMVDRYNLYYAYLPAKLEKKMHFSAVNQALAAPILCLFWLYFFSFLRLGFKAPTTMFTLLVVSITIAVCVAYTCFACFKHLSPLNYKIEDMQGESGSTDVRTTPASSMYIPRVLHPHSTERTMFAHEEQQTYGTMGNDTLGAEVTSYSAQSAIGRIAEGSI", "length": 802, "header": "tr|F1P4T6-1|F1P4T6_CHICK Isoform 1 of Transmembrane protein 63A OS=Gallus gallus OX=9031 GN=TMEM63A PE=3 SV=4 CANONICAL=F1P4T6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0L2-1", "url": "https://www.uniprot.org/uniprotkb/F1P4T6/entry#A0A8V0Z0L2-1", "sequence": { "sequence": "MSPVFFLGIGRSHLAYSWNRSGLFNSTNETYCYSTARGSTVLQGVTFGGIPTVLLLDVTCFFILILLFSIIRKRFWDYGRVALVSEAECGVRYTHSSASSSAPEVLEYDSGFCSWMAAAFRMHDDEIHDRCGEDAIHYLTFQRHIICLLVAVSILSVGVILPVNLSGDLLVKDPYSFGRTTIQNLETGNNLLWLHTFFAVVYLILTVVFMSHHMKTVTYKEENIVKCTLFITGLPKNAKQEAIEGHFIAAYPTCTVLEVQLCYDVARLIHLFRKRNEAEKSLDYYKRLYEKHGKRAKINPKPCGQFCCCEMRGCKREDAVDYYTRVTNELIEEFSKEEQAVQNKPLGMAFVTFQEKSMATYILKDFNACKCRSIKCKGEPQPSSYSKELRVTNWEVKYATYPENICWNNLSVCGLNWWVRWWCINLSLLILLFFLTTPSIIISTMDKFNVTKPIHYLNNPIISQFFPTLLLWSFSALLPTIVYYSTLLESHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFDRESSDSAIRLECVFLPDQGAFFVNYVIASAFVGNGMELLRLPGLILYTIRMIMAKSSAERKNIKQQQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYMLLKHMVDRYNLYYAYLPAKLEKKMHFSAVNQALAAPILCLFWLYFFSFLRLGFKAPTTMFTLLVVSITIAVCVAYTCFACFKHLSPLNYKIEDMQGESGSTDVRTTPASSVRS", "length": 751, "header": "tr|A0A8V0Z0L2-1|F1P4T6_CHICK Computationally mapped isoform of Transmembrane protein 63A OS=Gallus gallus OX=9031 GN=TMEM63A PE=3 SV=1 CANONICAL=F1P4T6-1" }, "locus": { "chromosome": "3", "start_pos": 16906996, "end_pos": 16881470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038355.1", "url": "https://www.ensembl.org/id/ENSGALT00010038355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022170.1", "url": "https://www.ensembl.org/id/ENSGALP00010022170.1" } ] } }, { "isoform_ac": "F1P4T6-1", "url": "https://www.uniprot.org/uniprotkb/F1P4T6/entry#F1P4T6-1", "sequence": { "sequence": "MSPVFFLGIGRSHLAYSWNRSGLFNSTNETYCYSTARGSTVLQGVTFGGIPTVLLLDVTCFFILILLFSIIRKRFWDYGRVALVSEAECGVRYTHSSASSSAPEVLEYDSGFCSWMAAAFRMHDDEIHDRCGEDAIHYLTFQRHIICLLVAVSILSVGVILPVNLSGDLLVKDPYSFGRTTIQNLETGNNLLWLHTFFAVVYLILTVVFMSHHMKTVTYKEENIVKCTLFITGLPKNAKQEAIEGHFIAAYPTCTVLEVQLCYDVARLIHLFRKRNEAEKSLDYYKRLYEKHGKRAKINPKPCGQFCCCEMRGCKREDAVDYYTRVTNELIEEFSKEEQAVQNKPLGMAFVTFQEKSMATYILKDFNACKCRSIKCKGEPQPSSYSKELRVTNWEVKYATYPENICWNNLSVCGLNWWVRWWCINLSLLILLFFLTTPSIIISTMDKFNVTKPIHYLNNPIISQFFPTLLLWSFSALLPTIVYYSTLLESHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFDRESSDSAIRLECVFLPDQGAFFVNYVIASAFVGNGMELLRLPGLILYTIRMIMAKSSAERKNIKQQQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYMLLKHMVDRYNLYYAYLPAKLEKKMHFSAVNQALAAPILCLFWLYFFSFLRLGFKAPTTMFTLLVVSITIAVCVAYTCFACFKHLSPLNYKIEDMQGESGSTDVRTTPASSMYIPRVLHPHSTERTMFAHEEQQTYGTMGNDTLGAEVTSYSAQSAIGRIAEGSI", "length": 802, "header": "tr|F1P4T6-1|F1P4T6_CHICK Isoform 1 of Transmembrane protein 63A OS=Gallus gallus OX=9031 GN=TMEM63A PE=3 SV=4 CANONICAL=F1P4T6-1" }, "locus": { "chromosome": "3", "start_pos": 16907736, "end_pos": 16881470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038361.1", "url": "https://www.ensembl.org/id/ENSGALT00010038361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022176.1", "url": "https://www.ensembl.org/id/ENSGALP00010022176.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421319", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421319", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1QMV7-1", "protein_name": "Transmembrane protein 63A", "gene_name": "TMEM63A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTDSPFLEMWPSRAVAIRERLGIGDQRNDSYCYNSAKNSTVLQGVTFGGIPTVLFIDVTCFLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSSSSGQQDFESELGCCPWLTAIFRLQDDQILEWCGEDAIHYLSFQRHIIFLLVVVSALSLCVILPVNLSGNLLDKDPFSFGRTTIANLQTDNNLLWLHTVFAIIYLILTVGFMRHHTQSIKYKEESLVRRTLFITGLPRNAKKETVESHFRDAYPTCEVVEVQLCYNVAKLIYLCKERKKTEKSLTYYTNLQVKTGQRTLINPKPCGQFCCCEVRGCEWEDAIAYYTRLKARLMERITEEECRVQDQPLGLAFVTFQEKSMATYILKDFNACKCQGLQCKGEPQPSSYGRDLCISKWTVTFASYPEDICWKNLSIQGFRWWFQWLGINFTLSVGLFFLTTPSIILSTMDKFNVTKPIHALNDPVISQFFPTLLLWSFSALLPTVVYYSTLLESHWTKSGENRIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEASIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMGMAKTVADRRNIKQNQAFEFEFGAMYAWMLCVFTVIMAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKRIHFAAVNQALAAPILCLFWLYFFSFLRLGLKAPLTLFTFLVVLLTILVCLAYTCFGCFKHLSPLNYKMEESAASDRGSEVGAHLPPPFTPYVPRILNSSSSEKTALSPQQQQTYGAIHNISGTVPGQCVVQSPADSVAATYQEA", "length": 805 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LPC4-1", "protein_name": "Transmembrane protein 63a", "gene_name": "Tmem63a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSSPFLDPWPSKAVSIRERLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVGCFLVLILVFSIIRRKFWDYGRIALVSEAGSEARFRRLSSSSSGQQDFESELGCCSWLSAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKETVESHFRDAYPTCEVVDVQLCYSVAKLINLCKERKKTEKSLTYYTNLQVKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLTERITAEECRVQDQPLGMAFVTFREKSMATFILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWSVTFASYPEDICWKNLSIQGVRWWLQCLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPTIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSDTSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFFSFLRLGLTAPATLFTFLVALLAILACLLYTCFGCFKHLSPWNYKTEEPVGDKRNEAEAHAPPPFTPYVPRILNGLTSERTALSPQQQQTYGAIRNISGTLPGQLVAQDPSDTVAGVYQES", "length": 804 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94886-1", "protein_name": "Mechanosensitive cation channel TMEM63A", "gene_name": "TMEM63A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDSPFLELWQSKAVSIREQLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARKETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPCGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEASIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCFKHLSPLNYKTEEPASDKGSEAEAHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAIHNISGTIPGQCLAQSATGSVAAAPQEA", "length": 807 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q75JR4-1", "protein_name": "Uncharacterized protein", "gene_name": "orfR1062", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDSSSGSGSGEHLNRYNANDNAFVVTLVINCVVMLIFFLIFCIVRRKFKQFYQYRFEQHHKGVSVPPSDGFFSWVVDTIKYSDNSIKDTAGLDGFMYLRNVKTSFYICVVLMVISSVMLYPTNYYGKYNEHREKDEDGKLPDEVVGLTMISMGNIERGSHLLWVHLVFVFFVTIVVLWFSYQDYHLYSKERIQYKQQSRLSNYTIMLRDIPNSMFTREELSNYFKSHLSNPSDLLDVSLQYPAPHIYALVSERENFVKKYESAIESYRRTKEKPTTKIGFLGCFGEEKDSIDYFQEKIDELTKKIEYERAEAETGYYIKNANSNVGGSSFVIFNQRKVQKEMVQTIMHAKYHVLFSRYYAPDPNDVFWKNIHIGLKSYYVRSLIVAILTFALVFLWGIPVAFLSGFSNLETISRVKAFSWITDIISKSKILQGFLSGFLPNLILIIFMILLIPIIYALSRACGYFSNSRIEASVFSKYFLFLVFNVFLVSAIAGTIFQSIEQIANDPTSIIGSIANSLGGLSFQMINYILIAAAGSFGAILRIVGLIIQLIKLKWLAKTKRQIDDTLHQGPFAYGVNYAKNLLILQLTLAYSTLSPFILIFGAWYFGLSYLVQKYNIIWVNTPNYQCGGFMSPMHFRRTIIGLLIYHILMIGTFNVYKFYYGILVVICLVVTIVFWYFAEYKFKDISKSGIMDQYQKQQTDGTNSGDIEMKASGSSVINDSTSLNPTVHQEFHDASHSISEYNSNSYKPPYYELMKINNFDLDFPIGGSANV", "length": 773 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91YT8-1", "protein_name": "Mechanosensitive cation channel TMEM63A", "gene_name": "Tmem63a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSSPFLDPWPSKAVFVRERLGLGERPNDSYCYNSAKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSEAGSEARFQRLSSSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKETVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTYYTNLQAKTGRRTLINPKPCGQFCCCEVQGCEREDAISYYTRMNDSLLERITAEESRVQDQPLGMAFVTFREKSMATYILKDFNACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAAVNQALAAPILCLFWLFFFSFLRLGLTAPATLFTFLVVLLTILACLLYTCFGCFKHLSPWNYKTEESASDKGSEAEAHVPPPFTPYVPRILNGLASERTALSPQQQQTYGAIRNISGTLPGQPVAQDPSGTAAYAYQES", "length": 804 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FVQ5-1", "protein_name": "Hyperosmolality-gated Ca2+ permeable channel 1.8", "gene_name": "OSCA1.8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLQDIGVSALINLFGAFLFLIAFAVLRIQPINDRVYFPKWYLTGERNSPRRSDRTLVGKFVNLNYKTYFTFLNWMPQAMKMSESEIIRHAGLDSAIFLRIYTLGLKIFAPVMVLALVVLVPVNVSSGTLFFLKKELVVSNIDKLSISNVQPKSSKFFFHIAVEYIFTFWACFMLYREYNNVAIMRLQYLASQRRRPEQFTVVVRNVPDMPGHSVPDTVDQFFKTNHPEHYLCHQAVYNANTYAKLVKQRAKLQRWFDYYVLKHQRNPHKQPTCRTGFLGLWGKRVDSIEYYKQQIKEFDHNMSLERQKVLKDSKLMLPVAFVSFDSRWGAAVCAQTQQSKNPTLWLTSSAPEPRDIYWQNLAIPFISLTIRKLVIGVSVFALVFFYMIPIAFVQSLANLEGLDRVAPFLRPVTRLDFIKSFLQGFLPGLALKIFLWILPTVLLIMSKIEGYIALSTLERRAAAKYYYFMLVNVFLGSIIAGTAFEQLHSFLHQSPSQIPRTIGVSIPMKATFFITYIMVDGWAGIAGEILRLKPLVIFHLKNMFIVKTEEDRVRAMDPGFVDFKETIPSLQLYFLLGIVYTAVTPILLPFILIFFAFAYLVYRHQIINVYNQQYESCGAFWPHVHGRIIASLLISQLLLMGLLASKKAADSTPLLIILPILTLSFHKYCKHRFEPAFRQYPLEEAMAKDKLEKETEPELNMKADLADAYLHPIFHSFEKEVELSSSSSSEKETHQEETPEVRVDKHETQSSSPVTELGTSSHHHHVYNSTSPSSHYASAYEQSSSQYEYHYNTHQYEEHEYRYN", "length": 806 }, "evidence": [ { "id": "F1P4T6", "url": "https://omabrowser.org/oma/group/F1P4T6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "calcium-activated cation channel activity", "id": "GO:0005227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005227", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" }, { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "F1P4T6", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4T6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 802, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4T6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4T6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" }, { "id": "PF02714", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02714" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSC1/OSCA1-like 7TM region", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 690, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" }, { "id": "PF13967", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13967" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSC1/OSCA1-like N-terminal transmembrane", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 211, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T6" }, { "id": "PF14703", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14703" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSC1/OSCA1-like cytosolic", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 409, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 778, "end_pos": 780 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4F9-1", "uniprot_ac": "F1P4F9", "uniprot_id": "F1P4F9_CHICK", "mass": { "chemical_mass": 48717.0, "monoisotopic_mass": 48717.0 }, "refseq": { "ac": "XP_025005925", "name": "cysteinyl leukotriene receptor 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005925" }, "gene_names": [ { "name": "CYSLTR1", "type": "recommended", "evidence": [ { "id": "F1P4F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ] }, { "name": "CYSLTR1", "type": "synonym", "evidence": [ { "id": "XP_025005925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005925" } ] } ], "protein_names": [ { "name": "Cysteinyl leukotriene receptor 1", "type": "recommended", "evidence": [ { "id": "F1P4F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F9/entry#names_and_taxonomy" } ] }, { "name": "cysteinyl leukotriene receptor 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025005925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005925" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005925" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYSLTR1", "url": "https://www.uniprot.org/uniprotkb/F1P4F9", "locus": { "chromosome": "4", "start_pos": 1302212, "end_pos": 1376965, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017860", "url": "https://www.ensembl.org/id/ENSGALG00010017860" } ] } } ], "crossref": [ { "id": "F1P4F9", "url": "https://alphafold.ebi.ac.uk/entry/F1P4F9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004128", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428691", "url": "https://www.ncbi.nlm.nih.gov/gene/428691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428691", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMPYHVQ", "url": "https://omabrowser.org/oma/group/FMPYHVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3H0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4F9", "url": "https://www.orthodb.org/?gene=F1P4F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-391906", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025005925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4F9-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQTAQSRMKLWVDLPHVRCHCAFLSKAAPTCCFSRQPLKTAPTWSTAAPSEQSWGYRLPLIRKRPEIPLHPPSASQQEMTTFLNNSLCQHAIDDFRNRVYSTLYSMISIMGFAGNGVVLFVLIRTFRQRTAFQVYMFNLAVSDFLCVCTLPLRVVYYVHQGHWFFSDILCRISSYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTERKAKFVCIGIWIFVILTSTPFLMNGTYQHGNKTKCFEPPEDIQKTNIIVNLDFIALFLGFIIPFIIITICYTMIIRTLLKNSLKKNQANRKKAIWMIVIVTATFLVSFTPYHILRTVHLHVLRLRHASCEDTVYLQKSVVVTLPLAAANCCFDPLLYFFSGGNFRKRLTTFRKASSSSITQAFRKKFSLKERDDEPFGESHKENGNAPVVAL", "length": 425, "header": "tr|F1P4F9-1|F1P4F9_CHICK Isoform 1 of Cysteinyl leukotriene receptor 1 OS=Gallus gallus OX=9031 GN=CYSLTR1 PE=4 SV=2 CANONICAL=F1P4F9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3H0-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F9/entry#A0A8V0Z3H0-1", "sequence": { "sequence": "MDQDRRSNGQRNGGEAQECRPEIPLHPPSASQQEMTTFLNNSLCQHAIDDFRNRVYSTLYSMISIMGFAGNGVVLFVLIRTFRQRTAFQVYMFNLAVSDFLCVCTLPLRVVYYVHQGHWFFSDILCRISSYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTERKAKFVCIGIWIFVILTSTPFLMNGTYQHGNKTKCFEPPEDIQKTNIIVNLDFIALFLGFIIPFIIITICYTMIIRTLLKNSLKKNQANRKKAIWMIVIVTATFLVSFTPYHILRTVHLHVLRLRHASCEDTVYLQKSVVVTLPLAAANCCFDPLLYFFSGGNFRKRLTTFRKASSSSITQAFRKKFSLKERDDEPFGESHKENGNAPVVAL", "length": 379, "header": "tr|A0A8V0Z3H0-1|A0A8V0Z3H0_CHICK Computationally mapped isoform of Cysteinyl leukotriene receptor 1 OS=Gallus gallus OX=9031 GN=CYSLTR1 PE=4 SV=1 CANONICAL=F1P4F9-1" }, "locus": { "chromosome": "4", "start_pos": 1318734, "end_pos": 1303856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043177.1", "url": "https://www.ensembl.org/id/ENSGALT00010043177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025645.1", "url": "https://www.ensembl.org/id/ENSGALP00010025645.1" } ] } }, { "isoform_ac": "A0A8V0ZAZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F9/entry#A0A8V0ZAZ1-1", "sequence": { "sequence": "MTTFLNNSLCQHAIDDFRNRVYSTLYSMISIMGFAGNGVVLFVLIRTFRQRTAFQVYMFNLAVSDFLCVCTLPLRVVYYVHQGHWFFSDILCRISSYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTERKAKFVCIGIWIFVILTSTPFLMNGTYQHGNKTKCFEPPEDIQKTNIIVNLDFIALFLGFIIPFIIITICYTMIIRTLLKNSLKKNQANRKKAIWMIVIVTATFLVSFTPYHILRTVHLHVLRLRHASCEDTVYLQKSVVVTLPLAAANCCFDPLLYFFSGGNFRKRLTTFRKASSSSITQAFRKKFSLKERDDEPFGESHKENGNAPVVAL", "length": 345, "header": "tr|A0A8V0ZAZ1-1|A0A8V0ZAZ1_CHICK Computationally mapped isoform of Cysteinyl leukotriene receptor 1 OS=Gallus gallus OX=9031 GN=CYSLTR1 PE=4 SV=1 CANONICAL=F1P4F9-1" }, "locus": { "chromosome": "4", "start_pos": 1304890, "end_pos": 1303856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043192.1", "url": "https://www.ensembl.org/id/ENSGALT00010043192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025659.1", "url": "https://www.ensembl.org/id/ENSGALP00010025659.1" } ] } }, { "isoform_ac": "F1P4F9-1", "url": "https://www.uniprot.org/uniprotkb/F1P4F9/entry#F1P4F9-1", "sequence": { "sequence": "MAAQTAQSRMKLWVDLPHVRCHCAFLSKAAPTCCFSRQPLKTAPTWSTAAPSEQSWGYRLPLIRKRPEIPLHPPSASQQEMTTFLNNSLCQHAIDDFRNRVYSTLYSMISIMGFAGNGVVLFVLIRTFRQRTAFQVYMFNLAVSDFLCVCTLPLRVVYYVHQGHWFFSDILCRISSYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTERKAKFVCIGIWIFVILTSTPFLMNGTYQHGNKTKCFEPPEDIQKTNIIVNLDFIALFLGFIIPFIIITICYTMIIRTLLKNSLKKNQANRKKAIWMIVIVTATFLVSFTPYHILRTVHLHVLRLRHASCEDTVYLQKSVVVTLPLAAANCCFDPLLYFFSGGNFRKRLTTFRKASSSSITQAFRKKFSLKERDDEPFGESHKENGNAPVVAL", "length": 425, "header": "tr|F1P4F9-1|F1P4F9_CHICK Isoform 1 of Cysteinyl leukotriene receptor 1 OS=Gallus gallus OX=9031 GN=CYSLTR1 PE=4 SV=2 CANONICAL=F1P4F9-1" }, "locus": { "chromosome": "4", "start_pos": 1315414, "end_pos": 1303856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043175.1", "url": "https://www.ensembl.org/id/ENSGALT00010043175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025644.1", "url": "https://www.ensembl.org/id/ENSGALP00010025644.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428691", "resource": "KEGG Pathway" }, { "id": "R-GGA-391906", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "resource": "Reactome", "description": "Leukotriene receptors" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRT7-1", "protein_name": "Cysteinyl leukotriene receptor 1", "gene_name": "CYSLTR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGVRNLTVSSASSNTCNDTIDDFRNQVYSTLYSMITVVGFFGNGFVLYVLIKTYHEKSAYQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLITHKKAKIVCIAIWIFVILTSSPFLMSTSYKDEKNNTKCFEPPQDNQAKYHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKNSMKKNISSRKKAIGMIIVVTAAFLISFMPYHIQRTIHLHFLHNDTKHCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTFRKHSLSSMTYVPKKKTSLPEKGEEIYKE", "length": 340 }, "evidence": [ { "id": "F1P4F9", "url": "https://omabrowser.org/oma/group/F1P4F9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q924T8-1", "protein_name": "Cysteinyl leukotriene receptor 1", "gene_name": "Cysltr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGAENMTASFSNNRCHDTIDEFRNQVYSTMYSMISVVGFFGNSFVLYVLIKTYHEKSAFQVYMINLAIADLLCVCTLPLRVVYYVHKGKWFFGDFLCRLTTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLLSKSYQDEKNNTKCFEPPQDKQTKKYVLVLHYVSLIFGFIIPFVTIIVCYTMIILTLLKNTMKKNLPSRRKAIGMIIVVTAAFLVSFMPYHIQRAIHLHFLHSETRSCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTFRKHSLSSMTYIPKKKASLPEKGEEMCKE", "length": 339 }, "evidence": [ { "id": "F1P4F9", "url": "https://omabrowser.org/oma/group/F1P4F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99JA4-1", "protein_name": "Cysteinyl leukotriene receptor 1", "gene_name": "Cysltr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYLQGTKQTFLENMNGTENLTTSLINNTCHDTIDEFRNQVYSTMYSVISVVGFFGNSFVLYVLIKTYHEKSAFQVYMINLAIADLLCVCTLPLRVVYYVHKGKWLFGDFLCRLTTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNINLVTQKKARFVCIGIWIFVILTSSPFLMYKSYQDEKNNTKCFEPPQNNQAKKYVLILHYVSLFFGFIIPFVTIIVCYTMIILTLLKNTMKKNMPSRRKAIGMIIVVTAAFLVSFMPYHIQRTIHLHLLHSETRPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTFRKHSLSSMTYVPKKKASLPEKGEEICNE", "length": 352 }, "evidence": [ { "id": "F1P4F9", "url": "https://omabrowser.org/oma/group/F1P4F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y271-1", "protein_name": "Cysteinyl leukotriene receptor 1", "gene_name": "CYSLTR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV", "length": 337 }, "evidence": [ { "id": "F1P4F9", "url": "https://omabrowser.org/oma/group/F1P4F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "leukotriene receptor activity", "id": "GO:0004974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004974", "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "pmid": "" }, { "name": "cysteinyl leukotriene receptor activity", "id": "GO:0001631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001631", "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "F1P4F9", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4F9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 425, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4F9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4F9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4F9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 370, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6UK13-1", "uniprot_ac": "F6UK13", "uniprot_id": "F6UK13_CHICK", "mass": { "chemical_mass": 29583.0, "monoisotopic_mass": 29583.0 }, "refseq": { "ac": "NP_001026530", "name": "large ribosomal subunit protein bL28m", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" }, "gene_names": [ { "name": "MRPL28", "type": "recommended", "evidence": [ { "id": "F6UK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ] }, { "name": "MRPL28", "type": "synonym", "evidence": [ { "id": "NP_001026530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL28m", "type": "recommended", "evidence": [ { "id": "F6UK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UK13/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L28, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001026530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" }, { "id": "F6UK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6UK13/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein bL28m", "type": "synonym", "evidence": [ { "id": "NP_001026530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" } ] }, { "name": "melanoma antigen P15", "type": "synonym", "evidence": [ { "id": "NP_001026530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01107005.1, HAEK01145511.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Oct 19, 2010 this sequence version replaced NP_001026530.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026530", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL28", "url": "https://www.uniprot.org/uniprotkb/F6UK13", "locus": { "chromosome": "14", "start_pos": 12146143, "end_pos": 12142971, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019313", "url": "https://www.ensembl.org/id/ENSGALG00010019313" } ] } } ], "crossref": [ { "id": "F6UK13", "url": "https://alphafold.ebi.ac.uk/entry/F6UK13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007473", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426121", "url": "https://www.ncbi.nlm.nih.gov/gene/426121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426121", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMSNRLK", "url": "https://omabrowser.org/oma/group/KMSNRLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3K5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6UK13", "url": "https://www.orthodb.org/?gene=F6UK13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13528:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13528:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026530", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026530", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6UK13-1", "url": "https://www.uniprot.org/uniprotkb/F6UK13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLHKVPPRLWPKLRLQEGICARLPAHFLAQLNDDTQPTPVHWRPLGVRYRRNPRTGERERVQDVPVPVFLPRAADEGLWGGEGWIRGFRYANNDKLSTRVPKIWKPQLFKRQFYSEILDAKLTITVTMRTLDLIDQAYGFDFYILKTPKADMCSKLGMDLKRTMLLRLARRDPKLHPDDPARREAIYNKYREFVIPEEEAEWVGLSLEEAIEKQRLLEKKDPVPLFKVYAEELVNQLKEQALEKEKERNV", "length": 251, "header": "tr|F6UK13-1|F6UK13_CHICK Isoform 1 of Large ribosomal subunit protein bL28m OS=Gallus gallus OX=9031 GN=MRPL28 PE=1 SV=1 CANONICAL=F6UK13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3K5-1", "url": "https://www.uniprot.org/uniprotkb/F6UK13/entry#A0A8V0Z3K5-1", "sequence": { "sequence": "MVLHKVPPRLWPKLRLQEGICARLPAHFLAQLNDDTQPTPVHWRPLGVRYRRNPRTGERERVQDVPVPVFLPRAADEGLWGGEGWIRGFRYANNDKLSTRVPKIWKPQLFKRQFYSEILDAKLTITVTMRTLDLIDQAYGFDFYILKTPKADMCSKLGMDLKRTMLLRLARRDPKLHPDDPARREAIYNKYREFVIPEEEAEWVGLSLEEAIEKQRLLEKKEVALQSS", "length": 228, "header": "tr|A0A8V0Z3K5-1|A0A8V0Z3K5_CHICK Computationally mapped isoform of Large ribosomal subunit protein bL28m OS=Gallus gallus OX=9031 GN=MRPL28 PE=1 SV=1 CANONICAL=F6UK13-1" }, "locus": { "chromosome": "14", "start_pos": 12144748, "end_pos": 12143023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046708.1", "url": "https://www.ensembl.org/id/ENSGALT00010046708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027816.1", "url": "https://www.ensembl.org/id/ENSGALP00010027816.1" } ] } }, { "isoform_ac": "F6UK13-1", "url": "https://www.uniprot.org/uniprotkb/F6UK13/entry#F6UK13-1", "sequence": { "sequence": "MVLHKVPPRLWPKLRLQEGICARLPAHFLAQLNDDTQPTPVHWRPLGVRYRRNPRTGERERVQDVPVPVFLPRAADEGLWGGEGWIRGFRYANNDKLSTRVPKIWKPQLFKRQFYSEILDAKLTITVTMRTLDLIDQAYGFDFYILKTPKADMCSKLGMDLKRTMLLRLARRDPKLHPDDPARREAIYNKYREFVIPEEEAEWVGLSLEEAIEKQRLLEKKDPVPLFKVYAEELVNQLKEQALEKEKERNV", "length": 251, "header": "tr|F6UK13-1|F6UK13_CHICK Isoform 1 of Large ribosomal subunit protein bL28m OS=Gallus gallus OX=9031 GN=MRPL28 PE=1 SV=1 CANONICAL=F6UK13-1" }, "locus": { "chromosome": "14", "start_pos": 12145819, "end_pos": 12143023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046710.1", "url": "https://www.ensembl.org/id/ENSGALT00010046710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027818.1", "url": "https://www.ensembl.org/id/ENSGALP00010027818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426121", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZTW8-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "MRPL28", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLHKVPVGLWKQLRLWEGIYSRLPRHYLRSLEEARTPTPVHYRPHGAKFKINPKNWQRERVEDVPIPVHYPPESQLGLWGGEGWVLGHRYVNNDKLSKRVRKVWKPQLFQRELYSEILDKRFTVTVTMRTLDLIDQACGFDFYILKTPKEDLCSKFGMDLKRGMLLRLARQDPQLHPDDPARRAAIYDRYKAFVIPEAEAEWVGLTLDEAVEKQRLLEEKDPIPLFKIFVEELLGQLQQQALSEPAVVQTRASRK", "length": 256 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJY1-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "Mrpl28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLHRYPVHLWQKLRLQQGICARLPSHFLRSLEEERTPTPVHYKPHGAKFKINPKNGQRERVEDVPIPVHYPPESQQELWGGEGLILGYRYANNDKLSNRVKKVWKPQLFTRELYSEILDKKFTVTVTMRTLDLIDEAYGFDFYILKTPEEDLCSKFGMDLKRGMLLRLARQDPQLHPDNPERRAAIYDKYRNFVIPEAEAEWVGLTLEEALEKQRLLEEKDPVPLFKVYVEELVQRLQEQALSRPAVVQKRAGDHV", "length": 257 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HBS6-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "Mrpl28", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPLHKYPVHLWQKLRLRQGIYARLPAHFLRSLEEERTPTPVHYKPHGAKFKINPKNGQRERVEDVPIPIYYPPESQQGLWGGEGVILGYRYANNDKLSTRVKKVWKPQLFTRELYSEILDKKFTVTVTMRTLDLIDEAYGFDFYILKTPKEDLCSKFGMDLKRGMLLRLARQDPQLHPDDPERRQAIYDKYKGFVIPEAEAEWVGLTLEEAVEKQRLLEEKDPVPLFKVYVEELVQRLQEQVLSRPAVVQKRAGDHA", "length": 257 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13084-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "MRPL28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLHKYPVWLWKRLQLREGICSRLPGHYLRSLEEERTPTPVHYRPHGAKFKINPKNGQRERVEDVPIPIYFPPESQRGLWGGEGWILGQIYANNDKLSKRLKKVWKPQLFEREFYSEILDKKFTVTVTMRTLDLIDEAYGLDFYILKTPKEDLCSKFGMDLKRGMLLRLARQDPQLHPEDPERRAAIYDKYKEFAIPEEEAEWVGLTLEEAIEKQRLLEEKDPVPLFKIYVAELIQQLQQQALSEPAVVQKRASGQ", "length": 256 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJJ1-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "MRPL28", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLHKVPVGLWKRLRLREGIYSRLPAHYLRSLEEARTPTPVHFRPHGAKFKINPKNGQRERVEDVPIPVHYPPESQLGLWGGEGWLKGHRYVNNDKFSKRVKKVWKPQLFQRELYSEILDTRFTVTVTMRTLDLIDEAYGFDFYILKTPKEDLCSKFGMDLKRGMLLRLARQDPQLHPDDPERRAAIYDKYKAFVIPEAEAEWVGLTLDEAVEKQRLLEEKDPVPLFKVYVEELVEQLQQQALSEPAVVQKRANRT", "length": 256 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D1B9-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "Mrpl28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLHRYPVHLWQKLRLRQGICARLPAHFLRSLEEERTPTPVHYKPHGTKFKINPKNGQRERVEDVPIPVHYPPESQQGLWGGEGLILGYRYANNDKLSKRVKKVWKPQLFTRELYSEILDKKFTVTVTMRTLDLIDEAYGFDFYILKTPKEDLGSKFGMDLKRGMLLRLARQDPHLHPENPERRAAIYDKYRSFVIPEAEAEWVGLTLEEALEKQRLLEEKDPVPLFKVYVEELVQRLQEQVLSRPAVVQKRAGDHA", "length": 257 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMX0-1", "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "mRpL28", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAHATPQGVKLLNGWKRPGRFDKGLGAQLPEAYRKFWREWKLTTPAAVHYIPKEQQWERDEVTHAIKPVQNIPLPLIDTPESHRGIWGGEAVIKGFQKREQTKRRVPHFWVPNLRRSVVHSHVLDCYMSVVVTERTLEQIHECHGFDHYLLKNRACDLRSALALKLKREVLQALQNGVPALADEPERQQEVLKEYRRYLEPYTPEEIDWYGHTYLEAIRKLQKQLREAEKVVPHKLEFRGKLIEQLRQAGISEAGKLEKPDALAAESSVEHKDSDIEALTKLESSPSSSWLSKINPFGKKET", "length": 302 }, "evidence": [ { "id": "F6UK13", "url": "https://omabrowser.org/oma/group/F6UK13/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F6UK13", "url": "https://www.uniprot.org/uniprotkb/F6UK13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P3Y5-1", "uniprot_ac": "F1P3Y5", "uniprot_id": "CF144_CHICK", "mass": { "chemical_mass": 15231.0, "monoisotopic_mass": 15231.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP144", "type": "recommended", "evidence": [ { "id": "F1P3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ] }, { "name": "FAM183A", "type": "recommended", "evidence": [ { "id": "F1P3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ] }, { "name": "FAM183A", "type": "synonym", "evidence": [ { "id": "F1P3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 144", "type": "recommended", "evidence": [ { "id": "F1P3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM183A", "type": "synonym", "evidence": [ { "id": "F1P3Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5#function" }, { "database": "UniProtKB", "id": "A6NL82", "url": "https://www.uniprot.org/uniprotkb/A6NL82#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP144", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5", "locus": {} } ], "crossref": [ { "id": "F1P3Y5", "url": "https://alphafold.ebi.ac.uk/entry/F1P3Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009033", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009033", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424557", "url": "https://www.ncbi.nlm.nih.gov/gene/424557", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQEIGWM", "url": "https://omabrowser.org/oma/group/SQEIGWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQI3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3Y5", "url": "https://www.orthodb.org/?gene=F1P3Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33865:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33865:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:F1P3Y5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:F1P3Y5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGGKKEPPDAVHLNRLLYERVRKELRCQRLHTEHSINPLRPVHAVTQKPMSWHDNIEEPADARFLNIIHQAALEPTKKYSEPQTESQEIGWNTTPLTDVDRTDRRLFFPRRRTEITMHSAAGGHPKKQ", "length": 131, "header": "sp|F1P3Y5-1|CF144_CHICK Isoform 1 of Cilia- and flagella-associated protein 144 OS=Gallus gallus OX=9031 GN=CFAP144 PE=1 SV=2 CANONICAL=F1P3Y5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQI3-1", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5/entry#A0A8V0ZQI3-1", "sequence": { "sequence": "MAARGGKKEPPDAVHLNRLLYERVRKELRCQRLHTEHSINPLRPVHAVTQKPMSWHDNIEEPADGEGNDPCPPTAGAGGGSVVSF", "length": 85, "header": "tr|A0A8V0ZQI3-1|A0A8V0ZQI3_CHICK Computationally mapped isoform of Family with sequence similarity 183 member A OS=Gallus gallus OX=9031 GN=FAM183A PE=3 SV=1 CANONICAL=F1P3Y5-1" }, "locus": { "chromosome": "8", "start_pos": 19302388, "end_pos": 19302009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054748.1", "url": "https://www.ensembl.org/id/ENSGALT00010054748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033087.1", "url": "https://www.ensembl.org/id/ENSGALP00010033087.1" } ] } }, { "isoform_ac": "F1P3Y5-1", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5/entry#F1P3Y5-1", "sequence": { "sequence": "MAARGGKKEPPDAVHLNRLLYERVRKELRCQRLHTEHSINPLRPVHAVTQKPMSWHDNIEEPADARFLNIIHQAALEPTKKYSEPQTESQEIGWNTTPLTDVDRTDRRLFFPRRRTEITMHSAAGGHPKKQ", "length": 131, "header": "sp|F1P3Y5-1|CF144_CHICK Isoform 1 of Cilia- and flagella-associated protein 144 OS=Gallus gallus OX=9031 GN=CFAP144 PE=1 SV=2 CANONICAL=F1P3Y5-1" }, "locus": { "chromosome": "8", "start_pos": 19303646, "end_pos": 19302009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054733.1", "url": "https://www.ensembl.org/id/ENSGALT00010054733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033074.1", "url": "https://www.ensembl.org/id/ENSGALP00010033074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "The transcriptional signature associated with human motile cilia.", "journal": "Sci. Rep.", "date": "2020", "authors": "Patir Anirudh, Fraser Amy M, Barnett Mark W, McTeir Lynn, Rainger Joe, Davey Megan G, Freeman Tom C", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "reference": [ { "type": "PubMed", "id": "32616903", "url": "https://glygen.org/publication/PubMed/32616903" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A8QW39-1", "protein_name": "Cilia- and flagella-associated protein 144", "gene_name": "CFAP144", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGHQKEKAIADEVHQNQILRELYLKELRTQKLYTQYHVNPLRKVHTIARKPMSWHDNLEEPADARFLNLIHHAAQGPRKKYPETQTEGQEIGWDSEPLVNPQRDDRRLNHFRVYKDITLYKAKMWSLGEDDRHK", "length": 135 }, "evidence": [ { "id": "F1P3Y5", "url": "https://omabrowser.org/oma/group/F1P3Y5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3Z8P9-1", "protein_name": "Cilia and flagella associated protein 144", "gene_name": "Cfap144", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMAGRLGQKMNQDEVHQNQIMRELFLKEFRTQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLVHHAAQGPKKKYSETQTEAQEIGWDPHPLINPDRQDRRLNHFRVYHDITLYKAKLWSLGEDDHQK", "length": 137 }, "evidence": [ { "id": "F1P3Y5", "url": "https://omabrowser.org/oma/group/F1P3Y5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SFB7-1", "protein_name": "Cilia and flagella associated protein 144", "gene_name": "CFAP144", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRQKEKVIRDEVHQNQILRELYLKELRTQILYTQYHVNPLRKVHTIARKPMSWHDNLEEPEDARFLNLIHHAAQGPRKKYPETQTESQEIGWDSEPLVNPARDDRRLNHFRVYNDITLYKAKMWSLGEKDRHK", "length": 135 }, "evidence": [ { "id": "F1P3Y5", "url": "https://omabrowser.org/oma/group/F1P3Y5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5NC57-1", "protein_name": "Cilia- and flagella-associated protein 144", "gene_name": "Cfap144", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRVGQMKNQDEVHQNQILRELFLKELRAQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLIHHAAQGPKKKYSETQTEAQEIGWDPNPLINPDRQDHRLNHFRVYHDITLYKAKLWSLGEDDHQK", "length": 135 }, "evidence": [ { "id": "F1P3Y5", "url": "https://omabrowser.org/oma/group/F1P3Y5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1P3Y5", "url": "https://www.uniprot.org/uniprotkb/F1P3Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P08636-1", "uniprot_ac": "P08636", "uniprot_id": "RS17_CHICK", "mass": { "chemical_mass": 15538.0, "monoisotopic_mass": 15538.0 }, "refseq": { "ac": "NP_989548", "name": "small ribosomal subunit protein eS17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" }, "gene_names": [ { "name": "RPS17", "type": "recommended", "evidence": [ { "id": "P08636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08636" } ] }, { "name": "RPS17L", "type": "synonym", "evidence": [ { "id": "NP_989548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" } ] }, { "name": "RPS17", "type": "synonym", "evidence": [ { "id": "NP_989548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein eS17", "type": "recommended", "evidence": [ { "id": "P08636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08636/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S17", "type": "synonym", "evidence": [ { "id": "NP_989548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" }, { "id": "P08636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08636/entry#names_and_taxonomy" } ] }, { "name": "small ribosomal subunit protein eS17", "type": "synonym", "evidence": [ { "id": "NP_989548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU234197.1, HAEL01014643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000245.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548" } ] }, { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636#function" }, { "database": "UniProtKB", "id": "P08708", "url": "https://www.uniprot.org/uniprotkb/P08708#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS17", "url": "https://www.uniprot.org/uniprotkb/P08636", "locus": { "chromosome": "10", "start_pos": 1362214, "end_pos": 1365023, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023334", "url": "https://www.ensembl.org/id/ENSGALG00010023334" } ] } } ], "crossref": [ { "id": "P08636", "url": "https://alphafold.ebi.ac.uk/entry/P08636", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002157", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "374053", "url": "https://www.ncbi.nlm.nih.gov/gene/374053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374053", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTEHIEV", "url": "https://omabrowser.org/oma/group/HTEHIEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0B5", "url": "https://www.orthodb.org/?gene=A0A8V1A0B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P08636", "url": "https://www.orthodb.org/?gene=P08636", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10732:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10732:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10732:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10732:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P08636", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P08636", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P08636-1", "url": "https://www.uniprot.org/uniprotkb/P08636-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAL", "length": 135, "header": "sp|P08636-1|RS17_CHICK Isoform 1 of Small ribosomal subunit protein eS17 OS=Gallus gallus OX=9031 GN=RPS17 PE=1 SV=3 CANONICAL=P08636-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0B5-1", "url": "https://www.uniprot.org/uniprotkb/P08636/entry#A0A8V1A0B5-1", "sequence": { "sequence": "SSRSTTPVWATTSTPTSACARRSPSSPARSCATRSRGEARGGGTLPCSAPALPQRPRGSPPPVCVCVCDPPSRRLSRRYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAL", "length": 161, "header": "tr|A0A8V1A0B5-1|RS17_CHICK Computationally mapped isoform of Small ribosomal subunit protein eS17 OS=Gallus gallus OX=9031 GN=RPS17 PE=1 SV=1 CANONICAL=P08636-1" }, "locus": { "chromosome": "10", "start_pos": 1364747, "end_pos": 1363029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056883.1", "url": "https://www.ensembl.org/id/ENSGALT00010056883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034591.1", "url": "https://www.ensembl.org/id/ENSGALP00010034591.1" } ] } }, { "isoform_ac": "P08636-1", "url": "https://www.uniprot.org/uniprotkb/P08636/entry#P08636-1", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAL", "length": 135, "header": "sp|P08636-1|RS17_CHICK Isoform 1 of Small ribosomal subunit protein eS17 OS=Gallus gallus OX=9031 GN=RPS17 PE=1 SV=3 CANONICAL=P08636-1" }, "locus": { "chromosome": "10", "start_pos": 1364937, "end_pos": 1363029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056882.1", "url": "https://www.ensembl.org/id/ENSGALT00010056882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034590.1", "url": "https://www.ensembl.org/id/ENSGALP00010034590.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence of a cDNA clone encoding chicken ribosomal protein S17.", "journal": "Nucleic Acids Res.", "date": "1988", "authors": "Tr\u00fceb B, Schreier T, Winterhalter K H, Strehler E E", "evidence": [ { "database": "UniProtKB", "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636" } ], "reference": [ { "type": "PubMed", "id": "3380698", "url": "https://glygen.org/publication/PubMed/3380698" } ] } ], "pathway": [ { "id": "gga:374053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374053", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140T832-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGQINSSFRPLDADGPSTFPFYFASAPLGVAVVRWSRLSASQARRKRLSGLRFIGLSCASCFLFYQGPANMGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 205 }, "evidence": [ { "id": "P08636", "url": "https://omabrowser.org/oma/group/P08636/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P02407-1", "protein_name": "Small ribosomal subunit protein eS17A", "gene_name": "RPS17A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRV", "length": 136 }, "evidence": [ { "id": "P08636", "url": "https://omabrowser.org/oma/group/P08636/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "P08636", "url": "https://omabrowser.org/oma/group/P08636/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08708-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV", "length": 135 }, "evidence": [ { "id": "P08636", "url": "https://omabrowser.org/oma/group/P08636/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63274-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "P08636", "url": "https://omabrowser.org/oma/group/P08636/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P63276-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10090, "organism": "Mus 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"https://www.uniprot.org/uniprotkb/P08636" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "P08636", "url": "https://www.uniprot.org/uniprotkb/P08636" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P08636-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 135, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P08636-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P08636" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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"url": "https://www.uniprot.org/uniprotkb/F6SU35" } ] }, { "name": "RPL10A", "type": "synonym", "evidence": [ { "id": "XP_418020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418020" } ] } ], "protein_names": [ { "name": "Ribosomal protein", "type": "recommended", "evidence": [ { "id": "F6SU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6SU35/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L10a isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418020" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418020" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL10A", "url": "https://www.uniprot.org/uniprotkb/F6SU35", "locus": { "chromosome": "26", "start_pos": 4175503, "end_pos": 4171087, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025904", "url": "https://www.ensembl.org/id/ENSGALG00010025904" } ] } } ], "crossref": [ { "id": "F6SU35", "url": "https://alphafold.ebi.ac.uk/entry/F6SU35", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002644", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419895", "url": "https://www.ncbi.nlm.nih.gov/gene/419895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR002143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPRNKMP", "url": "https://omabrowser.org/oma/group/GPRNKMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9M2", "url": "https://www.orthodb.org/?gene=A0A8V1A9M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6SU35", "url": "https://www.orthodb.org/?gene=F6SU35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": 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"F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6SU35-1", "url": "https://www.uniprot.org/uniprotkb/F6SU35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKVSRDTLYEAVKEVLQGSKTKKRKFVETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCLLGDQQHCDEAKAVEIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTEDELVYNIHLAINFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217, "header": "tr|F6SU35-1|F6SU35_CHICK Isoform 1 of Ribosomal protein OS=Gallus gallus OX=9031 GN=RPL10A PE=1 SV=1 CANONICAL=F6SU35-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9M2-1", "url": "https://www.uniprot.org/uniprotkb/F6SU35/entry#A0A8V1A9M2-1", "sequence": { "sequence": "MSSKVSRDTLYEAVKEVLQGSKTKKRKFVETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCLLGDQQHCDEAKAVEIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLVAKVDEVKSTIKFQMKKVSLQCLPAAPGEEPPALCRAAEGHNHQSIQLLTGKEQLICG", "length": 202, "header": "tr|A0A8V1A9M2-1|F6SU35_CHICK Computationally mapped isoform of Ribosomal protein OS=Gallus gallus OX=9031 GN=RPL10A PE=1 SV=1 CANONICAL=F6SU35-1" }, "locus": { "chromosome": "26", "start_pos": 4173473, "end_pos": 4171120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063139.1", "url": "https://www.ensembl.org/id/ENSGALT00010063139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038976.1", "url": "https://www.ensembl.org/id/ENSGALP00010038976.1" } ] } }, { "isoform_ac": "F6SU35-1", "url": "https://www.uniprot.org/uniprotkb/F6SU35/entry#F6SU35-1", "sequence": { "sequence": "MSSKVSRDTLYEAVKEVLQGSKTKKRKFVETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCLLGDQQHCDEAKAVEIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTEDELVYNIHLAINFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217, "header": "tr|F6SU35-1|F6SU35_CHICK Isoform 1 of Ribosomal protein OS=Gallus gallus OX=9031 GN=RPL10A PE=1 SV=1 CANONICAL=F6SU35-1" }, "locus": { "chromosome": "26", "start_pos": 4174744, "end_pos": 4171120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063143.1", "url": "https://www.ensembl.org/id/ENSGALT00010063143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038978.1", "url": "https://www.ensembl.org/id/ENSGALP00010038978.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T0H0-1", "protein_name": "Ribosomal protein", "gene_name": "RPL10A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0CX43-1", "protein_name": "Large ribosomal subunit protein uL1A", "gene_name": "RPL1A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX44-1", "protein_name": "Large ribosomal subunit protein uL1B", "gene_name": "RPL1B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62906-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "RPL10A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62907-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "Rpl10a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E9E6-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "RPL10A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86L05-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "rpl10a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKISSDQVRSIVSQLFKEAQESKRGFLETVELQINLKNYDTKKDKRFSGQIKIGTVTKPKLSVCVFADQQHCDEATKIGAEFMDIEALKKIGPKNKKAIKKLSKKYDAFLASESILRQVPKLLGPGLNKVGKFPTLLTHSEDMASKINDVKSTVKFQLKKVLCLAVAVGHIELTEREVATNIIQSINFLVSLLKKGWQNIKTLYVKTSMGPSHRVY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VZB9-1", "protein_name": "Large ribosomal subunit protein uL1z", "gene_name": "RPL10AA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKLQSEAVREAITTITGKSEAKKRNFVETIELQIGLKNYDPQKDKRFSGSVKLPHIPRPKMKICMLGDAQHVEEAEKMGLENMDVESLKKLNKNKKLVKKLAKKYHAFLASESVIKQIPRLLGPGLNKAGKFPTLVSHQESLESKVNETKATVKFQLKKVLCMGVAVGNLSMEEKQIFQNVQMSVNFLVSLLKKNWQNVRCLYLKSTMGPPQRIF", "length": 216 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VTP4-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "RpL10Ab", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASKVSRDTLYEGVNGLLEASAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "length": 217 }, "evidence": [ { "id": "F6SU35", "url": "https://omabrowser.org/oma/group/F6SU35/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F6SU35", "url": "https://www.uniprot.org/uniprotkb/F6SU35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6SU35-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 217, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6SU35-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6SU35" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P28318-1", "uniprot_ac": "P28318", "uniprot_id": "M126_CHICK", "mass": { "chemical_mass": 14065.0, "monoisotopic_mass": 14065.0 }, "refseq": { "ac": "NP_001292080", "name": "protein MRP-126", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" }, "gene_names": [ { "name": "S100A12", "type": "recommended", "evidence": [ { "id": "P28318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28318" } ] }, { "name": "S100A12", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] }, { "name": "S100A9", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] }, { "name": "S100F", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] } ], "protein_names": [ { "name": "Protein MRP-126", "type": "recommended", "evidence": [ { "id": "P28318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28318/entry#names_and_taxonomy" } ] }, { "name": "S100 calcium binding protein A12", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] }, { "name": "S100 calcium binding protein A9 (calgranulin B)", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] }, { "name": "protein MRP-126", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] }, { "name": "small calcium-binding (MRP-like) protein", "type": "synonym", "evidence": [ { "id": "NP_001292080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X61200.1, BX264740.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2812691, SAMEA2812693 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Feb 25, 2015 this sequence version replaced XP_424012.4.", "evidence": [ { "database": "RefSeq", "id": "NP_001292080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P28318", "url": "https://www.uniprot.org/uniprotkb/P28318" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P28318", "locus": {} } ], "crossref": [ { "id": "P28318", "url": "https://alphafold.ebi.ac.uk/entry/P28318", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024272", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000024272", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426356", "url": "https://www.ncbi.nlm.nih.gov/gene/426356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426356", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEHLHEV", "url": "https://omabrowser.org/oma/group/HEHLHEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIE5", "url": "https://www.orthodb.org/?gene=A0A8V1AIE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P28318", "url": "https://www.orthodb.org/?gene=P28318", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P28318", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P28318", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-3000471", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5668599", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292080", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIE5-1", "url": 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"description": "Scavenging by Class B Receptors" }, { "id": "R-GGA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "P79105-1", "protein_name": "Protein S100-A12", "gene_name": "S100A12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKLEDHLEGIINIFHQYSVRVGHFDTLNKRELKQLITKELPKTLQNTKDQPTIDKIFQDLDADKDGAVSFEEFVVLVSRVLKTAHIDIHKE", "length": 92 }, "evidence": [ { "id": "P28318", "url": "https://omabrowser.org/oma/group/P28318/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P80310-1", "protein_name": "Protein S100-A12", "gene_name": "S100A12", "tax_id": 9823, "organism": "Sus scrofa", 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"H9L1Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1/entry#names_and_taxonomy" } ] }, { "name": "Cdh1/Hct1 homolog", "type": "synonym", "evidence": [ { "id": "H9L1Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1/entry#names_and_taxonomy" } ] }, { "name": "fizzy and cell division cycle 20 related 1", "type": "synonym", "evidence": [ { "id": "NP_001265019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265019" } ] }, { "name": "fizzy-related protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001265019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265019" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.130267.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000374.1. On Dec 3, 2021 this sequence version replaced NP_001265019.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265019" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FZR1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1", "locus": { "chromosome": "28", "start_pos": 1485203, "end_pos": 1499115, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028139", "url": "https://www.ensembl.org/id/ENSGALG00010028139" } ] } } ], "crossref": [ { "id": "H9L1Y1", "url": "https://alphafold.ebi.ac.uk/entry/H9L1Y1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002085", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002085", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395297", "url": "https://www.ncbi.nlm.nih.gov/gene/395297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395297", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395297", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHHEYEK", "url": "https://omabrowser.org/oma/group/FHHEYEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJH8", "url": "https://www.orthodb.org/?gene=A0A8V1AJH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "H9L1Y1", "url": "https://www.orthodb.org/?gene=H9L1Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:H9L1Y1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:H9L1Y1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174113", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174113", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176417", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176417", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69656", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69656", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L1Y1-1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQDYERRLLRQINIQNENTMPCVAEMRRTLTPSNSPMSSPSKHGDRFIPSRAGANWSINFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKSLFTYSLSTKRSSPDDGNEVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGTLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 493, "header": "tr|H9L1Y1-1|H9L1Y1_CHICK Isoform 1 of Fizzy-related protein homolog OS=Gallus gallus OX=9031 GN=FZR1 PE=3 SV=4 CANONICAL=H9L1Y1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJH8-1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1/entry#A0A8V1AJH8-1", "sequence": { "sequence": "MDQDYERRLLRQINIQNENTMPCVAEMRRTLTPSNSPMSSPSKHGDRFIPSRAGANWSINFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKSLFTYSLSTKRSSPDDGNEVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGTLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKVQCSVLLTRGSASLHPHQDLSHPPPSFKLQCGAFNSSPQSSLSLSNKIKRQI", "length": 388, "header": "tr|A0A8V1AJH8-1|H9L1Y1_CHICK Computationally mapped isoform of Fizzy-related protein homolog OS=Gallus gallus OX=9031 GN=FZR1 PE=3 SV=1 CANONICAL=H9L1Y1-1" }, "locus": { "chromosome": "28", "start_pos": 1494503, "end_pos": 1489679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068187.1", "url": "https://www.ensembl.org/id/ENSGALT00010068187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041930.1", "url": "https://www.ensembl.org/id/ENSGALP00010041930.1" } ] } }, { "isoform_ac": "H9L1Y1-1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1/entry#H9L1Y1-1", "sequence": { "sequence": "MDQDYERRLLRQINIQNENTMPCVAEMRRTLTPSNSPMSSPSKHGDRFIPSRAGANWSINFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKSLFTYSLSTKRSSPDDGNEVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGTLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 493, "header": "tr|H9L1Y1-1|H9L1Y1_CHICK Isoform 1 of Fizzy-related protein homolog OS=Gallus gallus OX=9031 GN=FZR1 PE=3 SV=4 CANONICAL=H9L1Y1-1" }, "locus": { "chromosome": "28", "start_pos": 1494503, "end_pos": 1487177, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068189.1", "url": "https://www.ensembl.org/id/ENSGALT00010068189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041932.1", "url": "https://www.ensembl.org/id/ENSGALP00010041932.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395297", "resource": "KEGG Pathway" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174113", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174113", "resource": "Reactome", "description": "SCF-beta-TrCP mediated degradation of Emi1" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-GGA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-GGA-176417", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176417", "resource": "Reactome", "description": "Phosphorylation of Emi1" }, { "id": "R-GGA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" }, { "id": "R-GGA-69656", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69656", "resource": "Reactome", "description": "Cyclin A:Cdk2-associated events at S phase entry" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WCA1-1", "protein_name": "Fizzy-related protein homolog", "gene_name": "Fzr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEHKGLFTYSLSSKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSVLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPALQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKPCPALQLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 499 }, "evidence": [ { "id": "H9L1Y1", "url": "https://omabrowser.org/oma/group/H9L1Y1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8LPL5-1", "protein_name": "Protein FIZZY-RELATED 3", "gene_name": "FZR3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASPQSTKTGLNLPAGMNQTSLRLETFSSSFRGISSLSSPSKSTCSDRFIPCRSSSRLHAFDLQDKEPTTPVKEGGNEAYSRLLKSELFGSDFASPLLSPAGGQGSASSPMSPCTNMLRFKTDRSNSSPSSPFSPSILGNDNGHSSDSSPPPKPPRKVPKTPHKVLDAPSLQDDFYLNVVDWSSQNVLAVGLGTCVYLWTASNSKVTKLCDLGPNDSVCSVQWTREGSYISIGTSHGQVQVWDGTQCKRVRTMGGHQTRTGVLAWNSRILSSGSRDRNILQHDIRVQSDFVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWNNHSQQPILKLTEHTAAVKAITWSPHQSSLLASGGGTADRCIRFWNTTNGNQLNSIDTGSQVCNLAWSKNVNEIVSTHGYSQNQIMLWKYPSMSKVATLTGHSMRVLYLATSPDGQTIVTGAGDETLRFWNVFPSVKMQTPVKDTGLWSLGRTQIR", "length": 481 }, "evidence": [ { "id": "H9L1Y1", "url": "https://omabrowser.org/oma/group/H9L1Y1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9R1K5-1", "protein_name": "Fizzy-related protein homolog", "gene_name": "Fzr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEHKGLFTYSLSSKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 493 }, "evidence": [ { "id": "H9L1Y1", "url": "https://omabrowser.org/oma/group/H9L1Y1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UM11-1", "protein_name": "Fizzy-related protein homolog", "gene_name": "FZR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR", "length": 496 }, "evidence": [ { "id": "H9L1Y1", "url": "https://omabrowser.org/oma/group/H9L1Y1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4H9-1", "protein_name": "Fizzy-related protein homolog", "gene_name": "fzr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSPEYEKRILKHYSPVARNLFNNFESSTTPTSLDRFIPCRAYNNWQTNFASINKSNDNSPQTSKKQRDCGETARDSLAYSCLLKNELLGSAIDDVKTAGEERNENAYTPAAKRSLFKYQSPTKQDYNGECPYSLSPVSAKSQKLLRSPRKATRKISRIPFKVLDAPELQDDFYLNLVDWSSQNVLAVGLGSCVYLWSACTSQVTRLCDLSPDANTVTSVSWNERGNTVAVGTHHGYVTVWDVAANKQINKLNGHSARVGALAWNSDILSSGSRDRWIIQRDTRTPQLQSERRLAGHRQEVCGLKWSPDNQYLASGGNDNRLYVWNQHSVNPVQSYTEHMAAVKAIAWSPHHHGLLASGGGTADRCIRFWNTLTGQPMQCVDTGSQVCNLAWSKHSSELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLALSPDGEAIVTGAGDETLRFWNVFSKARSQKENKSVLNLFANIR", "length": 478 }, "evidence": [ { "id": "H9L1Y1", "url": "https://omabrowser.org/oma/group/H9L1Y1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ubiquitin-protein transferase activator activity", "id": "GO:0097027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097027", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "negative regulation of cellular senescence", "id": "GO:2000773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "H9L1Y1", "url": "https://www.uniprot.org/uniprotkb/H9L1Y1" } ], "pmid": "" }, { "name": "positive regulation of 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4D4-1", "uniprot_ac": "F1P4D4", "uniprot_id": "F1P4D4_CHICK", "mass": { "chemical_mass": 33587.0, "monoisotopic_mass": 33587.0 }, "refseq": { "ac": "XP_415471", "name": "telomere length and silencing protein 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415471" }, "gene_names": [ { "name": "C9orf78", "type": "recommended", "evidence": [ { "id": "F1P4D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ] }, { "name": "C9orf78", "type": "synonym", "evidence": [ { "id": "XP_415471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415471" } ] } ], "protein_names": [ { "name": "Chromosome 9 open reading frame 78", "type": "synonym", "evidence": [ { "id": "F1P4D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4D4/entry#names_and_taxonomy" } ] }, { "name": "telomere length and silencing protein 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_415471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415471" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415471" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C9orf78", "url": "https://www.uniprot.org/uniprotkb/F1P4D4", "locus": { "chromosome": "17", "start_pos": 6310533, "end_pos": 6315441, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028498", "url": "https://www.ensembl.org/id/ENSGALG00010028498" } ] } } ], "crossref": [ { "id": "F1P4D4", "url": "https://alphafold.ebi.ac.uk/entry/F1P4D4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004152", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004152", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417189", "url": "https://www.ncbi.nlm.nih.gov/gene/417189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417189", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIKTGGM", "url": "https://omabrowser.org/oma/group/NIKTGGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKN9", "url": "https://www.orthodb.org/?gene=A0A8V1AKN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P4D4", "url": "https://www.orthodb.org/?gene=F1P4D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13486", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13486", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13486:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13486:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4D4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4D4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASRAFRRRREEPEEDEEDEQLAEEVRLKLEEAKEVQSLRKRPNGVSAAALLVGEKLQEEATLVDDPFKIKSGGMVDMKKLKERGKDRINEEEDLNLGTSFSAETNRRDEDADMMKYIETELKKRKGIVENEEQKVKLKNAEDSLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEEAKAKLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPVRRNKEEPKPRPLRVGDTERPEPERSPPNRKRPPNEKATDDYHYEKFKKMNRRY", "length": 289, "header": "tr|F1P4D4-1|F1P4D4_CHICK Isoform 1 of Chromosome 9 open reading frame 78 OS=Gallus gallus OX=9031 GN=C9orf78 PE=1 SV=2 CANONICAL=F1P4D4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKN9-1", "url": "https://www.uniprot.org/uniprotkb/F1P4D4/entry#A0A8V1AKN9-1", "sequence": { "sequence": "MAASRAFRRRREEPEEDEEDEQLAEEVSAAALLVGEKLQEEATLVDDPFKIKSGGMVDMKKLKERGKDRINEEEDLNLGTSFSAETNRRDEDADMMKYIETELKKRKGIVENEEQKVKLKNAEDSLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEEAKAKLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPVRRNKEEPKPRPLRVGDTERPEPERSPPNRKRPPNEKATDDYHYEKFKKMNRRY", "length": 269, "header": "tr|A0A8V1AKN9-1|F1P4D4_CHICK Computationally mapped isoform of Chromosome 9 open reading frame 78 OS=Gallus gallus OX=9031 GN=C9orf78 PE=1 SV=1 CANONICAL=F1P4D4-1" }, "locus": { "chromosome": "17", "start_pos": 6315392, "end_pos": 6311059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069003.1", "url": "https://www.ensembl.org/id/ENSGALT00010069003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042445.1", "url": "https://www.ensembl.org/id/ENSGALP00010042445.1" } ] } }, { "isoform_ac": "F1P4D4-1", "url": "https://www.uniprot.org/uniprotkb/F1P4D4/entry#F1P4D4-1", "sequence": { "sequence": "MAASRAFRRRREEPEEDEEDEQLAEEVRLKLEEAKEVQSLRKRPNGVSAAALLVGEKLQEEATLVDDPFKIKSGGMVDMKKLKERGKDRINEEEDLNLGTSFSAETNRRDEDADMMKYIETELKKRKGIVENEEQKVKLKNAEDSLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEEAKAKLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPVRRNKEEPKPRPLRVGDTERPEPERSPPNRKRPPNEKATDDYHYEKFKKMNRRY", "length": 289, "header": "tr|F1P4D4-1|F1P4D4_CHICK Isoform 1 of Chromosome 9 open reading frame 78 OS=Gallus gallus OX=9031 GN=C9orf78 PE=1 SV=2 CANONICAL=F1P4D4-1" }, "locus": { "chromosome": "17", "start_pos": 6315392, "end_pos": 6311059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069004.1", "url": "https://www.ensembl.org/id/ENSGALT00010069004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042446.1", "url": "https://www.ensembl.org/id/ENSGALP00010042446.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417189", "name": "", "url": 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"MPVTGKTFRRRRADSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKRTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY", "length": 289 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4HVZ5-1", "protein_name": "Protein COP1 SUPPRESSOR 2", "gene_name": "CSU2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPPKRNFRKRSFEEEEEDNDVNKAAISEEEEKRRLALEEVKFLQKLRERKLGIPALSSTAQSSIGKVKPVEKTETEGEKEELVLQDTFAQETAVLIEDPNMVKYIEQELAKKRGRNIDDAEEVENELKRVEDELYKIPDHLKVKKRSSEESSTQWTTGIAEVQLPIEYKLKNIEETEAAKKLLQERRLMGRPKSEFSIPSSYSADYFQRGKDYAEKLRREHPELYKDRGGPQADGEAAKPSTSSSTNNNADSGKSRQAATDQIMLERFRKRERNRVMRR", "length": 279 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3IGZ6-1", "protein_name": "Telomere length and silencing protein 1 homolog isoform X2", "gene_name": "CUNH9orf78", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRITGKTFRRRRADSESEEDEQESEEVRLKLEETREVQNLRKRPNGVSAAALLVGEKVQEETTLVDDPFQMTTGGMVDMKKLKERGKDKVSEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEQEEQKAKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY", "length": 289 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TQI7-1", "protein_name": "Splicing factor C9orf78 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRITGKTFRRRRADSESEEDEQESEEVRLKLEETREVQNLRKRPNGVSAAALLVGEKVQEETTLVDDPFQMATGGMVDMKKLKERGKDKVSEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEQEEQKAKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY", "length": 289 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XJ46-1", "protein_name": "Telomere length and silencing protein 1 homolog", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPGKNFRRRKEDSSDEEDDETKFVVRSKLDEAKELQSLRKRQHGVSIATLLVGEKLPLEAELEDDPFKLKTGGVVDMKKVKDRSRDMTVDENDLNLGTSFSAETNRRDEDADMMKYIETELKKKKGMVEAEEQKVKVKNPEDLLYELPENINVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIINTEEAKAKLLAEQRNKKKDSGTSFVPTNIAVNYVQHNRFYHEDSNAPQRRNREEPKARPLRVGDTEKPAPEASPPNFRKRPNNEKATDDYHYEKFKKMNRRY", "length": 289 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NZ63-1", "protein_name": "Splicing factor C9orf78", "gene_name": "C9orf78", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVVRKIFRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY", "length": 289 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0A9-1", "protein_name": "Telomere length and silencing protein 1 homolog", "gene_name": "Dmel\\CG7974", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDAEETKAEATTKVLFKKAGRKNLRQRKNSDEEEKEEQLTLDEIKERQRLRQRPNGVSLVGLALGKKIAPEEELAIKDPFNVKTGGLVNMKQLKSGKMKEADDAYDVGIGTQFSAETNKRDEDEEMMKYIEQELQKRKGGGTEDAAEDDGDVNKYLTPEDAALYALPDHLRQSSSHRSEEMLSNQMLNGIPEVDLGIVAKIRNIEATEEAKQKLLQDAKNKKDGPSQFVPTNMAVNFMQHNRFNIEDNSDQRRRKREEREGNKSAQHQTNPNGVKRATDDYHYDKFRKQFRRY", "length": 294 }, "evidence": [ { "id": "F1P4D4", "url": "https://omabrowser.org/oma/group/F1P4D4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of homologous chromosome segregation", "id": "GO:0060629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060629", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "F1P4D4", "url": "https://www.uniprot.org/uniprotkb/F1P4D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4D4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4D4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4D4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P2B2-1", "uniprot_ac": "F1P2B2", "uniprot_id": "F1P2B2_CHICK", "mass": { "chemical_mass": 43068.0, "monoisotopic_mass": 43068.0 }, "refseq": { "ac": "XP_422265", "name": "podocin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422265" }, "gene_names": [ { "name": "NPHS2", "type": "recommended", "evidence": [ { "id": "F1P2B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2B2" } ] }, { "name": "NPHS2", "type": "synonym", "evidence": [ { "id": "XP_422265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422265" } ] } ], "protein_names": [ { "name": "Podocin", "type": "recommended", "evidence": [ { "id": "F1P2B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2B2/entry#names_and_taxonomy" } ] }, { "name": "podocin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422265" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_422265.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422265" } ] }, { "annotation": "Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.", "evidence": [ { "database": "UniProtKB", "id": "F1P2B2", "url": "https://www.uniprot.org/uniprotkb/F1P2B2#function" }, { "database": "UniProtKB", "id": "ARBA00053394", "url": "https://www.uniprot.org/uniprotkb/ARBA00053394#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2B2", "url": "https://www.uniprot.org/uniprotkb/F1P2B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPHS2", "url": "https://www.uniprot.org/uniprotkb/F1P2B2", "locus": { "chromosome": "8", "start_pos": 6144091, "end_pos": 6137759, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010944", "url": "https://www.ensembl.org/id/ENSGALG00010010944" } ] } } ], "crossref": [ { "id": "F1P2B2", "url": "https://alphafold.ebi.ac.uk/entry/F1P2B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004163", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004163", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424422", "url": "https://www.ncbi.nlm.nih.gov/gene/424422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424422", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWDGFRA", "url": "https://omabrowser.org/oma/group/AWDGFRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P2B2", "url": "https://www.orthodb.org/?gene=F1P2B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10264:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10264:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422265", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422265", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P2B2", "url": "https://www.uniprot.org/uniprotkb/F1P2B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P2B2-1", "url": "https://www.uniprot.org/uniprotkb/F1P2B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMDKRSRSSSRESHRRKRESPATQRKQEKRERSKEASKETGDIRQGKTKEIKSTVGTDGRVHTSTVVDVDDVISDEEMEAMMLLDSEHQEEGMKSPGLNICEWLLTILSFLFIIMTFPISVWFCMKVVREYERAIVFRLGHLLPGRARGPGLFFFLPCLDTYHKVDLRLKTLEIPFHQVVTKDMVTLEIDAVCYYRLENASLLLTTLTSISSAIQLLVQTTTKRLLAHRAFSELLLERKSISQEIKVALDAVTGCWGIKVERTEINNVQLPAEVQQSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSSAPAAAQLRYLHALHSLAAEKPAAFILPLPLDPTNLVSSATRSPPGVNSIITDTTELRESVKDKKDSPML", "length": 384, "header": "tr|F1P2B2-1|F1P2B2_CHICK Isoform 1 of Podocin OS=Gallus gallus OX=9031 GN=NPHS2 PE=3 SV=2 CANONICAL=F1P2B2-1" }, "isoforms": [ { "isoform_ac": "F1P2B2-1", "url": "https://www.uniprot.org/uniprotkb/F1P2B2/entry#F1P2B2-1", "sequence": { "sequence": "MRMDKRSRSSSRESHRRKRESPATQRKQEKRERSKEASKETGDIRQGKTKEIKSTVGTDGRVHTSTVVDVDDVISDEEMEAMMLLDSEHQEEGMKSPGLNICEWLLTILSFLFIIMTFPISVWFCMKVVREYERAIVFRLGHLLPGRARGPGLFFFLPCLDTYHKVDLRLKTLEIPFHQVVTKDMVTLEIDAVCYYRLENASLLLTTLTSISSAIQLLVQTTTKRLLAHRAFSELLLERKSISQEIKVALDAVTGCWGIKVERTEINNVQLPAEVQQSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSSAPAAAQLRYLHALHSLAAEKPAAFILPLPLDPTNLVSSATRSPPGVNSIITDTTELRESVKDKKDSPML", "length": 384, "header": "tr|F1P2B2-1|F1P2B2_CHICK Isoform 1 of Podocin OS=Gallus gallus OX=9031 GN=NPHS2 PE=3 SV=2 CANONICAL=F1P2B2-1" }, "locus": { "chromosome": "8", "start_pos": 6143999, "end_pos": 6137795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026211.1", "url": "https://www.ensembl.org/id/ENSGALT00010026211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014835.1", "url": "https://www.ensembl.org/id/ENSGALP00010014835.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424422", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8K4G9-1", "protein_name": "Podocin", "gene_name": "Nphs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSRARSSSRKTHGRGSRSSSRDDKKSKAGRGNRGRARPDAGAERQSAGRTGTREEHRAPAATVVNVDEVRSPGEEGTEVVALLESERPEEGIKPSGLGACEWLLVLSSLIFIIVTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKVALDSVTCVWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTDKPSTVVLPLPFDMLNLLSSPSNRAQGSINYPSSPKPVEPLNPKRKDSPML", "length": 383 }, "evidence": [ { "id": "F1P2B2", "url": "https://omabrowser.org/oma/group/F1P2B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91X05-1", "protein_name": "Podocin", "gene_name": "Nphs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSRARSSSREAHGRSSRSSSRDDKKAKAGRGSRGRARPDAGAERQSTGRTATRGEPRAPAATATVVDVDEVRGPGEEGTEVVALLESERPEEGIKPSGLGACEWLLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKVALDAVTCIWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLSLLSSPGNRAQGSINYPSSSKPVEPLNPKKKDSPML", "length": 385 }, "evidence": [ { "id": "F1P2B2", "url": "https://omabrowser.org/oma/group/F1P2B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP85-1", "protein_name": "Podocin", "gene_name": "NPHS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML", "length": 383 }, "evidence": [ { "id": "F1P2B2", "url": "https://omabrowser.org/oma/group/F1P2B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P2B2", "url": "https://www.uniprot.org/uniprotkb/F1P2B2" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": 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"uniprot_id": "F1P2L0_CHICK", "mass": { "chemical_mass": 16359.0, "monoisotopic_mass": 16359.0 }, "refseq": { "ac": "NP_001020525", "name": "DNA polymerase epsilon subunit 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020525" }, "gene_names": [ { "name": "POLE3", "type": "recommended", "evidence": [ { "id": "F1P2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2L0" } ] }, { "name": "POLE3", "type": "synonym", "evidence": [ { "id": "NP_001020525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020525" } ] } ], "protein_names": [ { "name": "DNA polymerase epsilon subunit 3", "type": "recommended", "evidence": [ { "id": "F1P2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2L0/entry#names_and_taxonomy" } ] }, { "name": "DNA polymerase II subunit 3", "type": "synonym", "evidence": [ { "id": "F1P2L0", "database": "UniProtKB", "url": 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preliminary review. The reference sequence was derived from JAENSK010000308.1. On Apr 15, 2009 this sequence version replaced NP_001020525.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001020525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020525" } ] }, { "annotation": "Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication. Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex.", "evidence": [ { "database": "UniProtKB", "id": "F1P2L0", "url": "https://www.uniprot.org/uniprotkb/F1P2L0#function" }, { "database": "UniProtKB", "id": "ARBA00045219", "url": "https://www.uniprot.org/uniprotkb/ARBA00045219#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2L0", "url": "https://www.uniprot.org/uniprotkb/F1P2L0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLE3", "url": "https://www.uniprot.org/uniprotkb/F1P2L0", "locus": { "chromosome": "17", "start_pos": 2117490, "end_pos": 2113208, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027932", "url": "https://www.ensembl.org/id/ENSGALG00010027932" } ] 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"https://www.ncbi.nlm.nih.gov/protein/XP_004938835" }, "gene_names": [ { "name": "GPR12", "type": "recommended", "evidence": [ { "id": "F1P2L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2L2" } ] }, { "name": "GPR12", "type": "synonym", "evidence": [ { "id": "XP_004938835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938835" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 12", "type": "synonym", "evidence": [ { "id": "F1P2L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2L2/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 12", "type": "synonym", "evidence": [ { "id": "XP_004938835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938835" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938835" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2L2", "url": "https://www.uniprot.org/uniprotkb/F1P2L2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR12", "url": "https://www.uniprot.org/uniprotkb/F1P2L2", "locus": { "chromosome": "1", "start_pos": 176332682, "end_pos": 176319952, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005843", "url": "https://www.ensembl.org/id/ENSGALG00010005843" } ] } } ], "crossref": [ { "id": "ENSGALG00000017102", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017102", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15961", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15961", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428079", "url": "https://www.ncbi.nlm.nih.gov/gene/428079", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428079", "url": 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"url": "https://www.uniprot.org/uniprotkb/F1P2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEEPTVNASWLPQDRVEASSTENASGSSLVPVVEPEPELWVNPWDIVLCTSGTLISCENAVVVLIIFHNPSLRAPMFLLIGSLALADLLAGVGLIVNFVFAYLLRSEATKLVTVGLIVASFSASVGSLLAITVDRYLSLYYALTYNSERTVTFTYVMLILLWGAAICIGLLPVMGWNCLRDESTCSVIRPLTKNNAAVLSVSFLLMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALWLVCCGCVPSNLSQRARSPSDV", "length": 332, "header": "tr|F1P2L2-1|F1P2L2_CHICK Isoform 1 of G protein-coupled receptor 12 OS=Gallus gallus OX=9031 GN=GPR12 PE=3 SV=2 CANONICAL=F1P2L2-1" }, "isoforms": [ { "isoform_ac": "F1P2L2-1", "url": "https://www.uniprot.org/uniprotkb/F1P2L2/entry#F1P2L2-1", "sequence": { "sequence": 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"", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428079", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RTK1-1", "protein_name": "G protein-coupled receptor 12", "gene_name": "GPR12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNEDLKVNGSRPPRDYLDAGAAVNVSAAVSSQGPVVEPEPELVVNPWDIVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLIINFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVLGWNCLRDESTCSVVRPLTKNNAAILSISFLFMFAFMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLSQRARSPSDV", "length": 334 }, "evidence": [ { "id": "F1P2L2", "url": "https://omabrowser.org/oma/group/F1P2L2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GWJ0-1", "protein_name": "G-protein coupled receptor 12", "gene_name": "Gpr12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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The reference sequence was derived from JAENSK010000256.1. On Dec 16, 2021 this sequence version replaced NP_001007085.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001007085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007085" } ] }, { "annotation": "Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.", "evidence": [ { "database": "UniProtKB", "id": "F1P2P6", "url": "https://www.uniprot.org/uniprotkb/F1P2P6#function" }, { "database": "UniProtKB", "id": "RU363136", "url": "https://www.uniprot.org/uniprotkb/RU363136#function" } ] }, { "annotation": "The IL-5 gene lacks a recognizable promoter and regulatory sequences in the predicted 3'-untranslated region", "evidence": [ { "database": "RefSeq", "id": "NP_001007085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007085" }, { "database": "PubMed", "id": "15626157", "url": "https://glygen.org/publication/PubMed/15626157" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2P6", "url": 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"publication": [ { "title": "Characterization of the first nonmammalian T2 cytokine gene cluster: the cluster contains functional single-copy genes for IL-3, IL-4, IL-13, and GM-CSF, a gene for IL-5 that appears to be a pseudogene, and a gene encoding another cytokinelike transcript, KK34.", "journal": "Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research", "date": "2004-10", "authors": "Avery Stuart, Rothwell Lisa, Degen Winfried D J, Schijns Virgil E J C, Young John, Kaufman Jim, Kaiser Pete", "evidence": [ { "database": "RefSeq", "id": "NP_001007085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007085" } ], "reference": [ { "type": "PubMed", "id": "15626157", "url": "https://glygen.org/publication/PubMed/15626157" } ] } ], "pathway": [ { "id": "gga:474360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:474360", "resource": "KEGG Pathway" }, { "id": "R-GGA-512988", "name": "", 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 355, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4G9-1", "uniprot_ac": "F1P4G9", "uniprot_id": "F1P4G9_CHICK", "mass": { "chemical_mass": 38649.0, "monoisotopic_mass": 38649.0 }, "refseq": { "ac": "NP_001035556", "name": "LIM/homeobox protein Lhx8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" }, "gene_names": [ { "name": "LHX8", "type": "recommended", "evidence": [ { "id": "F1P4G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G9" } ] }, { "name": "LHX7", "type": "synonym", "evidence": [ { "id": "NP_001035556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ] }, { "name": "LHX8", "type": "synonym", "evidence": [ { "id": "NP_001035556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ] } ], "protein_names": [ { "name": "LIM homeobox 8", "type": "synonym", "evidence": [ { "id": "F1P4G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G9/entry#names_and_taxonomy" } ] }, { "name": "LIM/homeobox protein Lhx8", "type": "synonym", "evidence": [ { "id": "NP_001035556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX929966.2, DQ082893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992428, SAMEA103992531 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Jul 10, 2015 this sequence version replaced NP_001035556.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ] }, { "annotation": "Expression of cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" }, { "database": "PubMed", "id": "18331888", "url": "https://glygen.org/publication/PubMed/18331888" } ] }, { "annotation": "The restricted expression of both LHX genes and IRF6 in the facial primordia suggests roles for these gene products in promoting directed outgrowth and fusion of the primary palate. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" }, { "database": "PubMed", "id": "16563169", "url": "https://glygen.org/publication/PubMed/16563169" } ] }, { "annotation": "Widely expressed in the craniofacial region and likely to play a critical role in the patterning and differentiation of maxilla.", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" }, { "database": "PubMed", "id": "16456677", "url": "https://glygen.org/publication/PubMed/16456677" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4G9", "url": "https://www.uniprot.org/uniprotkb/F1P4G9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LHX8", "url": "https://www.uniprot.org/uniprotkb/F1P4G9", "locus": { "chromosome": "8", "start_pos": 29402943, "end_pos": 29387713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024023", "url": "https://www.ensembl.org/id/ENSGALG00010024023" } ] } } ], "crossref": [ { "id": "F1P4G9", "url": "https://alphafold.ebi.ac.uk/entry/F1P4G9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011369", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011369", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09383", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09383", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424721", "url": "https://www.ncbi.nlm.nih.gov/gene/424721", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424721", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424721", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPMFVCK", "url": "https://omabrowser.org/oma/group/DPMFVCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P4G9", "url": "https://www.orthodb.org/?gene=F1P4G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208:SF117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208:SF117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P4G9", "url": "https://www.uniprot.org/uniprotkb/F1P4G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4G9-1", "url": "https://www.uniprot.org/uniprotkb/F1P4G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYWKSDPMFVCRLEDKDLPALGDTSEKESPAAADEDSCSSSAALSPSSSPRSMASGSGCAPSKCVCSSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGVSMEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSTAPVTAAQPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTALGLQPLLPHSMTQLPISHT", "length": 347, "header": "tr|F1P4G9-1|F1P4G9_CHICK Isoform 1 of LIM homeobox 8 OS=Gallus gallus OX=9031 GN=LHX8 PE=4 SV=3 CANONICAL=F1P4G9-1" }, "isoforms": [ { "isoform_ac": "F1P4G9-1", "url": "https://www.uniprot.org/uniprotkb/F1P4G9/entry#F1P4G9-1", "sequence": { "sequence": "MYWKSDPMFVCRLEDKDLPALGDTSEKESPAAADEDSCSSSAALSPSSSPRSMASGSGCAPSKCVCSSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGVSMEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSTAPVTAAQPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTALGLQPLLPHSMTQLPISHT", "length": 347, "header": "tr|F1P4G9-1|F1P4G9_CHICK Isoform 1 of LIM homeobox 8 OS=Gallus gallus OX=9031 GN=LHX8 PE=4 SV=3 CANONICAL=F1P4G9-1" }, "locus": { "chromosome": "8", "start_pos": 29402416, "end_pos": 29391446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058508.1", "url": "https://www.ensembl.org/id/ENSGALT00010058508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035563.1", "url": "https://www.ensembl.org/id/ENSGALP00010035563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression and regulation of the LIM homeodomain gene L3/Lhx8 suggests a role in upper lip development of the chick embryo.", "journal": "Anatomy and embryology", "date": "2006-06", "authors": "Inoue Masahide, Kawakami Masayoshi, Tatsumi Kouko, Manabe Takayuki, Makinodan Manabu, Matsuyoshi Hiroko, Kirita Tadaaki, Wanaka Akio", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ], "reference": [ { "type": "PubMed", "id": "16456677", "url": "https://glygen.org/publication/PubMed/16456677" } ] }, { "title": "Expression profiles of cIRF6, cLHX6 and cLHX7 in the facial primordia suggest specific roles during primary palatogenesis.", "journal": "BMC developmental biology", "date": "2006-03-24", "authors": "Washbourne Belinda J, Cox Timothy C", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ], "reference": [ { "type": "PubMed", "id": "16563169", "url": "https://glygen.org/publication/PubMed/16563169" } ] }, { "title": "Expression of cLhx6 and cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis.", "journal": "Brain research bulletin", "date": "2008-03-18", "authors": "Abell\u00e1n Antonio, Medina Loreta", "evidence": [ { "database": "RefSeq", "id": "NP_001035556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035556" } ], "reference": [ { "type": "PubMed", "id": "18331888", "url": "https://glygen.org/publication/PubMed/18331888" } ] } ], "pathway": [ { "id": "gga:424721", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424721", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BBB7-1", "protein_name": "LIM homeobox 8", "gene_name": "LHX8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYWKSDQMFVCKLEEKDVLELAVPLEKCQGLMSEECGRTAALAAGRTRKGAGEEGLVSPEGVGDEDSCSSSAPLSPSSSPRSMASGSVCPPGKCVCSSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSAPVTAVPPSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT", "length": 377 }, "evidence": [ { "id": "F1P4G9", "url": "https://omabrowser.org/oma/group/F1P4G9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V6V6-1", "protein_name": "LIM homeobox 8", "gene_name": "Lhx8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYWKSDQMFVCKLEGKDVPELAVPREKCPGLMSEECGRPAALAAGRTRKGAGEEGLVNPEGAGDEDSCSSSAPLSPSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHFDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSAPVTAVPSSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHQQLLDSSPCYPIQ", "length": 367 }, "evidence": [ { "id": "F1P4G9", "url": "https://omabrowser.org/oma/group/F1P4G9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35652-1", "protein_name": "LIM/homeobox protein Lhx8", "gene_name": "Lhx8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYWKSDQMFVCKLEGKEVPELAVPREKCPGLMSEECGRPAALAAGRTRKGAGEEGLVNPEGAGDEDSCSSSAPLSPSSSPQSMASGSVCPPGKCVCSSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHFDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSAPVTAVPSSRLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHQQLLDSSPCYPIQ", "length": 367 }, "evidence": [ { "id": "F1P4G9", "url": "https://omabrowser.org/oma/group/F1P4G9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68G74-1", "protein_name": "LIM/homeobox protein Lhx8", "gene_name": "LHX8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"F1P4Q0_CHICK", "mass": { "chemical_mass": 62907.0, "monoisotopic_mass": 62907.0 }, "refseq": { "ac": "NP_001001763", "name": "high affinity choline transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" }, "gene_names": [ { "name": "SLC5A7", "type": "recommended", "evidence": [ { "id": "F1P4Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ] }, { "name": "SLC5A7", "type": "synonym", "evidence": [ { "id": "NP_001001763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" } ] } ], "protein_names": [ { "name": "High affinity choline transporter 1", "type": "recommended", "evidence": [ { "id": "F1P4Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0/entry#names_and_taxonomy" } ] }, { "name": "Hemicholinium-3-sensitive choline transporter", "type": "synonym", "evidence": [ { "id": "F1P4Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 5 member 7", "type": "synonym", "evidence": [ { "id": "F1P4Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0/entry#names_and_taxonomy" } ] }, { "name": "high affinity choline transporter 1", "type": "synonym", "evidence": [ { "id": "NP_001001763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" } ] }, { "name": "solute carrier family 5 (choline transporter), member 7", "type": "synonym", "evidence": [ { "id": "NP_001001763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" } ] }, { "name": "solute carrier family 5 (sodium/choline cotransporter), member 7", "type": "synonym", "evidence": [ { "id": "NP_001001763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000025.1. On or before Dec 3, 2021 this sequence version replaced XP_015133320.1, XP_001234411.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763" } ] }, { "annotation": "High-affinity Na(+)-coupled choline transmembrane symporter. Functions as an electrogenic, voltage-dependent transporter with variable charge/choline stoichiometry. Choline uptake and choline-induced current is also Cl(-)-dependent where Cl(-) is likely a regulatory ion rather than cotransported ion. Plays a critical role in acetylcholine (ACh) synthesis by taking up the substrate choline from the synaptic cleft into the presynaptic nerve terminals after neurotransmitter release. SLC5A7/CHT1-mediated choline high-affinity transport in cholinergic neurons is the rate-limiting step for production of ACh, thereby facilitating communication by subsequent action potentials. Localized predominantly in presynaptic terminal intracellular organelles, and translocated to the plasma membrane in active form in response to neuronal activity.", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0#function" }, { "database": "UniProtKB", "id": "ARBA00056873", "url": "https://www.uniprot.org/uniprotkb/ARBA00056873#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC5A7", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0", "locus": { "chromosome": "1", "start_pos": 136181553, "end_pos": 136158262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015183", "url": "https://www.ensembl.org/id/ENSGALG00010015183" } ] } } ], "crossref": [ { "id": "F1P4Q0", "url": "https://alphafold.ebi.ac.uk/entry/F1P4Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016804", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016804", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11474", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11474", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414870", "url": "https://www.ncbi.nlm.nih.gov/gene/414870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:414870", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKTKNTG", "url": "https://omabrowser.org/oma/group/WKTKNTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P4Q0", "url": "https://www.orthodb.org/?gene=F1P4Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45897", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45897", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45897:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45897:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001001763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001763", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "76443", "url": "https://www.rhea-db.org/rhea/76443", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4Q0-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFHVEGLVAIAVFYLAILAVGIWAAWKTKNTSSDGDRSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLVLGGLFFAKPMRSKGYVTMLDPFQQLYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDINVNLSVIISALIATLYTLVGGLYSVAYTDVVQLFCIFLGLWISVPFALSNPAVTDIGFTAVHEVHQAPWLGTIGSLNIYTWLDNFLLLTFGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCIVMAIPAVLIGAIGASTAWNQTEYGVPDPIANKEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDREIVWVMRITVFLFGASATAMALLASSVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAIAGYLFGLVLRITGGEPYLYLQPLIYYPGCYPDENNIYVQRFPFKTLAMLTSFFTNIIVSYLAKYLFESGTLPPKLDFLDAVVARYSREHMDKATLVKSDNIVLNELAPVNPRHSLTLSSTFTNKEAFNYVDSSPDLSNTEDN", "length": 578, "header": "tr|F1P4Q0-1|F1P4Q0_CHICK Isoform 1 of High affinity choline transporter 1 OS=Gallus gallus OX=9031 GN=SLC5A7 PE=3 SV=1 CANONICAL=F1P4Q0-1" }, "isoforms": [ { "isoform_ac": "F1P4Q0-1", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0/entry#F1P4Q0-1", "sequence": { "sequence": "MPFHVEGLVAIAVFYLAILAVGIWAAWKTKNTSSDGDRSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLVLGGLFFAKPMRSKGYVTMLDPFQQLYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDINVNLSVIISALIATLYTLVGGLYSVAYTDVVQLFCIFLGLWISVPFALSNPAVTDIGFTAVHEVHQAPWLGTIGSLNIYTWLDNFLLLTFGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCIVMAIPAVLIGAIGASTAWNQTEYGVPDPIANKEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDREIVWVMRITVFLFGASATAMALLASSVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAIAGYLFGLVLRITGGEPYLYLQPLIYYPGCYPDENNIYVQRFPFKTLAMLTSFFTNIIVSYLAKYLFESGTLPPKLDFLDAVVARYSREHMDKATLVKSDNIVLNELAPVNPRHSLTLSSTFTNKEAFNYVDSSPDLSNTEDN", "length": 578, "header": "tr|F1P4Q0-1|F1P4Q0_CHICK Isoform 1 of High affinity choline transporter 1 OS=Gallus gallus OX=9031 GN=SLC5A7 PE=3 SV=1 CANONICAL=F1P4Q0-1" }, "locus": { "chromosome": "1", "start_pos": 136180549, "end_pos": 136159566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036588.1", "url": "https://www.ensembl.org/id/ENSGALT00010036588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021331.1", "url": "https://www.ensembl.org/id/ENSGALP00010021331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:414870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414870", "resource": "KEGG Pathway" }, { "id": "R-GGA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-GGA-9958517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958517", "resource": "Reactome", "description": "SLC-mediated bile acid transport" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SU25-1", "protein_name": "High affinity choline transporter 1", "gene_name": "SLC5A7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFQVEGLIAIVVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPDYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIINTDVHASIIVSALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSNSAVTDIGFTALHTKYQKPWLGTIESFEVYTWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCMVMALPPILIGAIGASTDWNQTTYKPDTPKDNQQADMILPIVLKYLCPMYISYFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDREIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIAGLFLRVTGGEPYLNLQPLIFYPGYYVEKNGIYNQRFPFKTLAMLTSFLSNICISYLAKYLFESGTLPPKLDMFDAVVARHSEENMDKTILVKNENIKLDELAPVKPRQSLTLSSTFTNQEAFLNIDSSPEGSGTEDNL", "length": 579 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I4F7-1", "protein_name": "High affinity choline transporter 1", "gene_name": "Slc5a7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNASVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIEPIEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPSICIGAIGASTDWNQTAYGFPDPKTKEEGDMILPIVLQYLCPGYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWIMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYTDKNGIYNQRFPFKTLSMVTSFLTNICVSYLAKYLFESGTLPPKLDVFDAVVSRHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ", "length": 580 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BGY9-1", "protein_name": "High affinity choline transporter 1", "gene_name": "Slc5a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ", "length": 580 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZV3-1", "protein_name": "High affinity choline transporter 1", "gene_name": "SLC5A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ", "length": 580 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMD7-1", "protein_name": "High affinity choline transporter 1", "gene_name": "Slc5a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGFPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYPDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDIFDAVVSRHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ", "length": 580 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VE46-1", "protein_name": "High-affinity choline transporter 1", "gene_name": "ChT", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MINIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIGHVEPKKHWLYIDYGLLLVFGGIPWQVYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAILGLAPLIKYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAGKDERNGRINPALESDDDLPVAEARRINQETAQAQVKKMLDNATGVKPSGGGGGHLQSQSGMAMPTAEQDNTAF", "length": 614 }, "evidence": [ { "id": "F1P4Q0", "url": "https://omabrowser.org/oma/group/F1P4Q0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "synaptic transmission, cholinergic", "id": "GO:0007271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007271", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "acetylcholine biosynthetic process", "id": "GO:0008292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008292", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" }, { "name": "choline transport", "id": "GO:0015871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015871", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "choline:sodium symporter activity", "id": "GO:0005307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005307", "evidence": [ { "database": "UniProtKB", "id": "F1P4Q0", "url": "https://www.uniprot.org/uniprotkb/F1P4Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "76443", "name": "", "equation": "choline(out) + n Na(+)(out) = choline(in) + n Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76443" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4Q0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 578, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4Q0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4Q0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P4T5-1", "uniprot_ac": "F1P4T5", "uniprot_id": "F1P4T5_CHICK", "mass": { "chemical_mass": 25563.0, "monoisotopic_mass": 25563.0 }, "refseq": { "ac": "XP_420371", "name": "lecithin retinol acyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420371" }, "gene_names": [ { "name": "LRAT", "type": "recommended", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ] }, { "name": "LRAT", "type": "synonym", "evidence": [ { "id": "XP_420371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420371" } ] } ], "protein_names": [ { "name": "Lecithin retinol acyltransferase", "type": "recommended", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.135", "type": "synonym", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylcholine--retinol O-acyltransferase", "type": "synonym", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5/entry#names_and_taxonomy" } ] }, { "name": "lecithin retinol acyltransferase", "type": "synonym", "evidence": [ { "id": "XP_420371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420371" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_420371.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420371" } ] }, { "annotation": "Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology.", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5#function" }, { "database": "UniProtKB", "id": "ARBA00058039", "url": "https://www.uniprot.org/uniprotkb/ARBA00058039#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRAT", "url": "https://www.uniprot.org/uniprotkb/F1P4T5", "locus": { "chromosome": "4", "start_pos": 19865314, "end_pos": 19862293, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014995", "url": "https://www.ensembl.org/id/ENSGALG00010014995" } ] } } ], "crossref": [ { "id": "F1P4T5", "url": "https://alphafold.ebi.ac.uk/entry/F1P4T5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009276", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009276", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422403", "url": "https://www.ncbi.nlm.nih.gov/gene/422403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422403", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFCLWMV", "url": "https://omabrowser.org/oma/group/PFCLWMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P4T5", "url": "https://www.orthodb.org/?gene=F1P4T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420371", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17469", "url": "https://www.rhea-db.org/rhea/17469", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43904", "url": "https://www.rhea-db.org/rhea/43904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55320", "url": "https://www.rhea-db.org/rhea/55320", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56240", "url": "https://www.rhea-db.org/rhea/56240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56244", "url": "https://www.rhea-db.org/rhea/56244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56248", "url": "https://www.rhea-db.org/rhea/56248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P4T5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4T5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNAVPQVASLLLEKLLLLVHVRALPAGTEGGESPPAASGYYDTSCFRRGDLLEVPRTLFVHFGIYLGENRVAHLMPDILPAFTDDHRQIQRVVTNKRLILGVITKTASIRVDTVEDFAYGGSILVNHMDRLFKDQVLGSEEAACRAEMLVGATAYSLLWNNCEHFVTYCRYGAPVSFQTDKFCETVKMIIRDQRSVLASVLVGLASIICLGLAPSTALPTIFITFVLWMAG", "length": 232, "header": "tr|F1P4T5-1|F1P4T5_CHICK Isoform 1 of Lecithin retinol acyltransferase OS=Gallus gallus OX=9031 GN=LRAT PE=3 SV=3 CANONICAL=F1P4T5-1" }, "isoforms": [ { "isoform_ac": "F1P4T5-1", "url": "https://www.uniprot.org/uniprotkb/F1P4T5/entry#F1P4T5-1", "sequence": { "sequence": "MKNAVPQVASLLLEKLLLLVHVRALPAGTEGGESPPAASGYYDTSCFRRGDLLEVPRTLFVHFGIYLGENRVAHLMPDILPAFTDDHRQIQRVVTNKRLILGVITKTASIRVDTVEDFAYGGSILVNHMDRLFKDQVLGSEEAACRAEMLVGATAYSLLWNNCEHFVTYCRYGAPVSFQTDKFCETVKMIIRDQRSVLASVLVGLASIICLGLAPSTALPTIFITFVLWMAG", "length": 232, "header": "tr|F1P4T5-1|F1P4T5_CHICK Isoform 1 of Lecithin retinol acyltransferase OS=Gallus gallus OX=9031 GN=LRAT PE=3 SV=3 CANONICAL=F1P4T5-1" }, "locus": { "chromosome": "4", "start_pos": 19863407, "end_pos": 19862323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036059.1", "url": "https://www.ensembl.org/id/ENSGALT00010036059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020938.1", "url": "https://www.ensembl.org/id/ENSGALP00010020938.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422403", "resource": "KEGG Pathway" }, { "id": "R-GGA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-GGA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IGP5-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKNPMLEAVSLLLEKLLLISNIKLFSVSTPGGGTEKNRPYEISSFLRGDVLEVSRTHFTHYGIYLGNNRVAHLMPDILLALTNDEGRTQKVVSNKRLIPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEVVACRAEQQLGMTPYSLLWNNCEHFATYCRYGAPISPQAEKFHETVKTIIRDQRSCLASAVLGLLSIVYTGLASYMTLPAICIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1Q7T8-1", "protein_name": "2.3.1.135", "gene_name": "lrata", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLDSLTFLFEKFFLFSNFNLFKSIWQPEKEECAVKCHPALRRGDLLEVQRTLFIHYGIYLGENRVAHLMPDIMPLLTSNKQHIKPVVTNKRLILGCMYRLASIRVDSVEDFAYGAPILTNDMDKKMKCQVLANEEVARRAEKLVGDIPYSLLWNNCEHFVTYCRYGTPVSEQTDKFCNCLKSIIRDQRSVALTIGMGVMYILCFGLAPSTTLPTILIPFILWMAG", "length": 225 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RYR6-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "LRAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLLISNFRLFSSGAPGEDKTRNTFYEISSYLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKELTQKVVSNKRLILGVICRVASIRVDTVEDFAYGADILVNHLDRSLKKKALLNEEVARRAEKQLGLSSYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIVCLGLAPYTTLPAIFIPFCLWMAG", "length": 230 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95237-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "LRAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG", "length": 230 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JI60-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGTGKNRPYEISSFVRGDVLEVSRTHFIHYGIYLGENRVAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDTVEDFAYGADILVNHLDGTLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSRISPQAEKFYDTVKIIIRDQRSSLASAVLGLASIVYTGLASYMTLPAICIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JI61-1", "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKNSMLEAASLLLEKLLLISNFKIFSVCAPGGGTGKKHPYEINSFLRGDVLEVSRTHFTHYGIYLGDNRVAHLMPDILLALTSDKERTQKVVSNKRLLPGVICKVASIRVDTVEDFAYGADILVNHLDETLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSPISPQAEKFHETVKILIRDQRSCLASAVLGLVSIIYTGLASYMTLPAVCIPFCLWMMSG", "length": 231 }, "evidence": [ { "id": "F1P4T5", "url": "https://omabrowser.org/oma/group/F1P4T5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "O-palmitoyltransferase activity", "id": "GO:0016416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016416", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "phosphatidylcholine-retinol O-acyltransferase activity", "id": "GO:0047173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047173", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "vitamin A metabolic process", "id": "GO:0006776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006776", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "F1P4T5", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17469", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "17469", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17469" } ] }, { "id": "43904", "name": "", "equation": "all-trans-retinol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "43904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43904" } ] }, { "id": "55320", "name": "", "equation": "1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = all-trans-retinyl heptanoate + 2-heptanoyl-sn-glycero-3-phosphocholine + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "55320", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55320" } ] }, { "id": "56240", "name": "", "equation": "1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "56240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56240" } ] }, { "id": "56244", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "56244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56244" } ] }, { "id": "56248", "name": "", "equation": "1,2-didodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-dodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl dodecanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "56248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56248" } ] }, { "id": "R-GGA-2404137", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-9982479", "R-GGA-74841" ], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "R-GGA-2404137", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2404137" } ] }, { "id": "R-GGA-2453855", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [ "R-ALL-9982900" ], "output_participant_list": [], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "R-GGA-2453855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453855" } ] }, { "id": "R-GGA-975608", "name": "LRAT esterifies RBP2:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-9982625", "R-GGA-975603" ], "enzyme_list": [ "F1P4T5-1" ], "evidence": [ { "id": "R-GGA-975608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975608" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9982479", "participant_name": "2acPC [plasma membrane]", "crossref": [ { "id": "57875", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9982625", "participant_name": "atRE [cytosol]", "crossref": [ { "id": "All-trans-Retinyl-Esters", "database": "AraCyc", "url": "" }, { "id": "C02075", "database": "COMPOUND", "url": "" }, { "id": "63410", "database": "ChEBI", "url": "" }, { "id": "C02075", "database": "KEGG Gene", "url": "" } ] }, { "participant_id": "R-ALL-9982900", "participant_name": "RCOO- [plasma membrane]", "crossref": [ { "id": "C02403", "database": "COMPOUND", "url": "" }, { "id": "28868", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-GGA-74841", "participant_name": "RBP1 [cytosol]", "crossref": [ { "id": "ENSGALP00010037959", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A6C6", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010061407", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010025172", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-975603", "participant_name": "RBP2 [cytosol]", "crossref": [ { "id": "ENSGALG00010025169", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010061391", "database": "ENSEMBL", "url": "" }, { "id": "F1NZY4", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010037950", "database": "ENSEMBL", "url": "" }, { "id": "NP_001264346.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1P4T5", "gene_name": "LRAT", "activity": [ { "ec_number": "2.3.1.135", "activity": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ] }, { "ec_number": "2.3.1.135", "activity": "", "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P4T5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 232, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P4T5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P4T5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4T5" }, { "id": "PS51934", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRAT", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 179, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.135", "ec_name": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "2.3.1.135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.135" }, { "id": "2.3.1.135", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.135" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P565-1", "uniprot_ac": "F1P565", "uniprot_id": "F1P565_CHICK", "mass": { "chemical_mass": 19245.0, "monoisotopic_mass": 19245.0 }, "refseq": { "ac": "XP_419709", "name": "tRNA-specific adenosine deaminase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419709" }, "gene_names": [ { "name": "ADAT2", "type": "recommended", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ] }, { "name": "ADAT2", "type": "synonym", "evidence": [ { "id": "XP_419709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419709" } ] } ], "protein_names": [ { "name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "type": "recommended", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.33", "type": "synonym", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565/entry#names_and_taxonomy" } ] }, { "name": "Deaminase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565/entry#names_and_taxonomy" } ] }, { "name": "tRNA-specific adenosine deaminase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419709" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419709" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P565", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAT2", "url": "https://www.uniprot.org/uniprotkb/F1P565", "locus": {} } ], "crossref": [ { "id": "F1P565", "url": "https://alphafold.ebi.ac.uk/entry/F1P565", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019976", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019976", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421670", "url": "https://www.ncbi.nlm.nih.gov/gene/421670", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421670", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421670", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCQMCAG", "url": "https://omabrowser.org/oma/group/PCQMCAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P565", "url": "https://www.orthodb.org/?gene=F1P565", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11079", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11079", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11079:SF149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11079:SF149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419709", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "43168", "url": "https://www.rhea-db.org/rhea/43168", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1P565", "url": "https://www.uniprot.org/uniprotkb/F1P565", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P565-1", "url": "https://www.uniprot.org/uniprotkb/F1P565-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDEAAWMERAFSMAQEALEAGEVPVGCLLVYDGAAIGKGRNEVNETKNATRHAEMVAIDQVLEWCQQHKKDHEEVFSHSVLYVTVEPCIMCAAALRLMKIPRVVYGCRNERFGGCGSVLSISSDDIVDTGEPFECIAGYRAKDAVEMLKAFYRQENPNAPKSKVRKKDNRK", "length": 172, "header": "tr|F1P565-1|F1P565_CHICK Isoform 1 of tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2 OS=Gallus gallus OX=9031 GN=ADAT2 PE=3 SV=4 CANONICAL=F1P565-1" }, "isoforms": [ { "isoform_ac": "F1P565-1", "url": "https://www.uniprot.org/uniprotkb/F1P565/entry#F1P565-1", "sequence": { "sequence": "MEDEAAWMERAFSMAQEALEAGEVPVGCLLVYDGAAIGKGRNEVNETKNATRHAEMVAIDQVLEWCQQHKKDHEEVFSHSVLYVTVEPCIMCAAALRLMKIPRVVYGCRNERFGGCGSVLSISSDDIVDTGEPFECIAGYRAKDAVEMLKAFYRQENPNAPKSKVRKKDNRK", "length": 172, "header": "tr|F1P565-1|F1P565_CHICK Isoform 1 of tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2 OS=Gallus gallus OX=9031 GN=ADAT2 PE=3 SV=4 CANONICAL=F1P565-1" }, "locus": { "chromosome": "3", "start_pos": 52160045, "end_pos": 52150678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013632.1", "url": "https://www.ensembl.org/id/ENSGALT00010013632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008082.1", "url": "https://www.ensembl.org/id/ENSGALP00010008082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:421670", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421670", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATE6-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "gene_name": "ADAT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAKGESTPAADGECSVSAEETEKWMEQAMQMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCHRGGKSPSEVFERTVLYVTVEPCIMCAAALRLMKIPLVVYGCQNERFGGCGSVLDIASADLPNTGRPFQCIPGYRAEEAVEMLKTFYKQENPNAPKSKVRKKECQKS", "length": 191 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P47058-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit TAD2", "gene_name": "TAD2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQHIKHMRTAVRLARYALDHDETPVACIFVHTPTGQVMAYGMNDTNKSLTGVAHAEFMGIDQIKAMLGSRGVVDVFKDITLYVTVEPCIMCASALKQLDIGKVVFGCGNERFGGNGTVLSVNHDTCTLVPKNNSAAGYESIPGILRKEAIMLLRYFYVRQNERAPKPRSKSDRVLDKNTFPPMEWSKYLNEEAFIETFGDDYRTCFANKVDLSSNSVDWDLIDSHQDNIIQELEEQCKMFKFNVHKKSKV", "length": 250 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5E9J7-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "gene_name": "DEADC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAKAGPTAATDGAYSVSAEETEKWMEQAMQMAKDALDNTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQALDWCRRRGRSPSEVFEHTVLYVTVEPCIMCAAALRLMRIPLVVYGCQNERFGGCGSVLDIASADLPSTGKPFQCTPGYRAEEAVEMLKTFYKQENPNAPKSKVRKKECHKS", "length": 191 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RIV4-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "gene_name": "adat2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQEVGVDPEKNDFLQPSDSEVQTWMAKAFDMAVEALENGEVPVGCLMVYNNEIIGKGRNEVNETKNATRHAEMVALDQVLDWCRLREKDCKEVCEQTVLYVTVEPCIMCAAALRLLRIPFVVYGCKNERFGGCGSVLDVSSDHLPHTGTSFKCIAGYRAEEAVEMLKTFYKQENPNAPKPKVRKDSINPQDGAAVIQVMRGPPDEETETIAHLS", "length": 214 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P6J0-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "gene_name": "Adat2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKVESTTTPDGPCVVSVQETEKWMEEAMRMAKEALENIEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCHQHGQSPSTVFEHTVLYVTVEPCIMCAAALRLMKIPLVVYGCQNERFGGCGSVLNIASADLPNTGRPFQCIPGYRAEEAVELLKTFYKQENPNAPKSKVRKKDCQKS", "length": 191 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z6V5-1", "protein_name": "tRNA-specific adenosine-34 deaminase catalytic subunit ADAT2", "gene_name": "ADAT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAKAAPKPAASGACSVSAEETEKWMEEAMHMAKEALENTEVPVGCLMVYNNEVVGKGRNEVNQTKNATRHAEMVAIDQVLDWCRQSGKSPSEVFEHTVLYVTVEPCIMCAAALRLMKIPLVVYGCQNERFGGCGSVLNIASADLPNTGRPFQCIPGYRAEEAVEMLKTFYKQENPNAPKSKVRKKECQKS", "length": 191 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEM0-1", "protein_name": "CMP/dCMP-type deaminase domain-containing protein", "gene_name": "Dmel\\CG5292", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAFMEEALVEARRARDAGEVPVGCVFVHGDKVVARGGNEVNVHRNATRHAEFICIDAILASCRERRLPARQLFSEITVVVTVEPCIMCSAALHTLGVKEIIYGCENDRFGGKTVVDVAAVVGHRIEITGGVRADEAMALLKDFYKGDNPAAPPQAKKKK", "length": 160 }, "evidence": [ { "id": "F1P565", "url": "https://omabrowser.org/oma/group/F1P565/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P565", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ], "pmid": "" }, { "name": "tRNA-specific adenosine-34 deaminase activity", "id": "GO:0052717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052717", "evidence": [ { "database": "UniProtKB", "id": "F1P565", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA wobble adenosine to inosine editing", "id": "GO:0002100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002100", "evidence": [ { "database": "UniProtKB", "id": "F1P565", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43168", "name": "", "equation": "adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P565-1" ], "evidence": [ { "id": "43168", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43168" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1P565", "gene_name": "ADAT2", "activity": [ { "ec_number": "3.5.4.33", "activity": "adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+).", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ] }, { "ec_number": "3.5.4.33", "activity": "", "evidence": [ { "id": "F1P565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P565" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P565-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 172, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P565-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P565" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.4.33", "ec_name": "adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+).", "evidence": [ { "id": "3.5.4.33", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.33" }, { "id": "3.5.4.33", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.33" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P5C0-1", "uniprot_ac": "F1P5C0", "uniprot_id": "F1P5C0_CHICK", "mass": { "chemical_mass": 85731.0, "monoisotopic_mass": 85731.0 }, "refseq": { "ac": "XP_417996", "name": "probable ATP-dependent RNA helicase DDX20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417996" }, "gene_names": [ { "name": "DDX20", "type": "recommended", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "name": "DDX20", "type": "synonym", "evidence": [ { "id": "XP_417996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417996" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX20", "type": "recommended", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.15", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "Component of gems 3", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 20", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein DP 103", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "Gemin-3", "type": "synonym", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#names_and_taxonomy" } ] }, { "name": "probable ATP-dependent RNA helicase DDX20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417996" } ] }, { "annotation": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0#function" }, { "database": "UniProtKB", "id": "ARBA00055865", "url": "https://www.uniprot.org/uniprotkb/ARBA00055865#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDX20", "url": "https://www.uniprot.org/uniprotkb/F1P5C0", "locus": { "chromosome": "26", "start_pos": 3332910, "end_pos": 3324562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027272", "url": "https://www.ensembl.org/id/ENSGALG00010027272" } ] } } ], "crossref": [ { "id": "F1P5C0", "url": "https://alphafold.ebi.ac.uk/entry/F1P5C0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001504", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001504", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419869", "url": "https://www.ncbi.nlm.nih.gov/gene/419869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419869", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQTQKAH", "url": "https://omabrowser.org/oma/group/FQTQKAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P5C0", "url": "https://www.orthodb.org/?gene=F1P5C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47959:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47959:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23680", "url": "https://www.rhea-db.org/rhea/23680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5C0-1", "url": "https://www.uniprot.org/uniprotkb/F1P5C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPAEGRFRTRDVLLPGGPSDFGSLLLSPPVLAGLEAAGFHRPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDALLLDSPATQVLILAPTREIAVQIHAVITTIGIKMEGLECHVFIGGTPLSQDKVRLKKCHIAVGSPGRIKQLIELDYLNTASIRLFILDEADKLLEEGSFQEQINWIYSSLPANKQMLAVSATYPESLANALTMYMREPTFVRLNPTDPSLIGLKQYYKIVNSHPLPHKTFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLAEILTSRGFPAECISGSMNQSQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVINLDVPVDWETYMHRIGRAGRFGTLGLSVTYCCRGEEENMMMKIAQKCNLQLLPLPEPIPPGMMDQFDDWEVEVKPVVYTGASVNSDTVCLKPEEPVLQPVQNNSAEVPQPHSNLPVGNSSVEKPKNALEQKLVKKHTNSAKVEKSSRNSKTSSCNTKQKNQVETVSRMAGQSNTEVPDEEALKRNLPRIPCLSSFKNQQNSPWNFSEFVEDYEYFIKEGLERDVEILRSFSGPGDQRELPRNGGIEWKEVECNRDTVANDVLSDDSDASYISRASSHGSENNSCFEAFSDRQAKNAVPTACQGLTGFCPTPGKLKELSQVPKQNQVKKKALKQNAKEKKKHSHQYPNPAPRKTGDDCSCGSWDDGVTGFPHEAWSYEDYWKSYYQAWQNYYAAVSHFHYRRSYRHLMWMNAYVNSVYFQELLESGD", "length": 767, "header": "tr|F1P5C0-1|F1P5C0_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX20 OS=Gallus gallus OX=9031 GN=DDX20 PE=1 SV=2 CANONICAL=F1P5C0-1" }, "isoforms": [ { "isoform_ac": "F1P5C0-1", "url": "https://www.uniprot.org/uniprotkb/F1P5C0/entry#F1P5C0-1", "sequence": { "sequence": "MAAPAEGRFRTRDVLLPGGPSDFGSLLLSPPVLAGLEAAGFHRPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDALLLDSPATQVLILAPTREIAVQIHAVITTIGIKMEGLECHVFIGGTPLSQDKVRLKKCHIAVGSPGRIKQLIELDYLNTASIRLFILDEADKLLEEGSFQEQINWIYSSLPANKQMLAVSATYPESLANALTMYMREPTFVRLNPTDPSLIGLKQYYKIVNSHPLPHKTFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLAEILTSRGFPAECISGSMNQSQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVINLDVPVDWETYMHRIGRAGRFGTLGLSVTYCCRGEEENMMMKIAQKCNLQLLPLPEPIPPGMMDQFDDWEVEVKPVVYTGASVNSDTVCLKPEEPVLQPVQNNSAEVPQPHSNLPVGNSSVEKPKNALEQKLVKKHTNSAKVEKSSRNSKTSSCNTKQKNQVETVSRMAGQSNTEVPDEEALKRNLPRIPCLSSFKNQQNSPWNFSEFVEDYEYFIKEGLERDVEILRSFSGPGDQRELPRNGGIEWKEVECNRDTVANDVLSDDSDASYISRASSHGSENNSCFEAFSDRQAKNAVPTACQGLTGFCPTPGKLKELSQVPKQNQVKKKALKQNAKEKKKHSHQYPNPAPRKTGDDCSCGSWDDGVTGFPHEAWSYEDYWKSYYQAWQNYYAAVSHFHYRRSYRHLMWMNAYVNSVYFQELLESGD", "length": 767, "header": "tr|F1P5C0-1|F1P5C0_CHICK Isoform 1 of Probable ATP-dependent RNA helicase DDX20 OS=Gallus gallus OX=9031 GN=DDX20 PE=1 SV=2 CANONICAL=F1P5C0-1" }, "locus": { "chromosome": "26", "start_pos": 3330759, "end_pos": 3324588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066122.1", "url": "https://www.ensembl.org/id/ENSGALT00010066122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040388.1", "url": "https://www.ensembl.org/id/ENSGALP00010040388.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 651, "start_aa": "Thr", "end_pos": 651, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr651", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419869", "resource": "KEGG Pathway" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MAM8-1", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "Ddx20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAFEALPASTTSESAMAAELEAAPVPAAEPTPASPWNLRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEILANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCNINLLPLPDPIPAGLMEECLDCDVEVKAAMHTYSSPSISTQSPKKQVQKPERAFQSQRTPGSHMPSPRNTSVSTLSAKSKHGKQKLPVKSHSECGILEKAAPPQELGCTTHPEEQVKNSVQTSTEESSSNSLHQAKETSPGSLPKIPCLSSFKVHQLSALTFAELVEDYEHYIKEGLEKPVEIIRHYTGPGAQTVNPQNGFVRNRVSADRVQMLVSSSQSGDSESESDSCSSRTSSQSKGNKSYLEGSSDTQLKDSECTSVGGPLSLEQIQNGNDTSTQVEYQESPETQVKARHKEGANQRSKPSRRNPPRRSSYRVQTEAQEEGWHDCHRETNASSSDPYQDYEEYWRAYYRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTVYLQEMMRGNQ", "length": 824 }, "evidence": [ { "id": "F1P5C0", "url": "https://omabrowser.org/oma/group/F1P5C0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MRW7-1", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "DDX20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAFEAPAALETVETAMPAERVATHFSAPEPASRPVRTLRTAHDISGPRTRTGDVLLAEPADFESLLLSRPVLEGLRAVGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMREPTFVRLNSSDPSLIGLKQYYKIVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPAEYISGNMDQNRRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDCETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCTINLLPLPDPIPPDLMEECLDWDVEVEAAMHTYGLASVPTQPLKKHIQKIERTFQTQKAHGKHMASSRNTSISTVSVKSKSNTKQKLPVKSHSECGIVEKVISPKELGCAVQPEEQMKNSVQTSIENPTNSQHQVKEASVSLPKIPCLSSFKTHLPCILTFAELVEDYEHYIKEGLEKPVEIIRHYTGPGDQSVNPQNGFVKNRITEERVQILASSSQSGDSESDSDSYSSRTSSQSKGNKSYLEVSSDTQLKDSESIPMDGHISLEQPLNGNDTPSLVEYQESTEIQVKTRHKEGANHNQRAKQSRRNLPRRSSYRLQTEPQEDGWYDCQRETHPSFSDTYQDYEEYWRAYYRAWQEYYAAASQSYYWNAQRHPSWMAAYQMNTVYLQEMMHSTQ", "length": 825 }, "evidence": [ { "id": "F1P5C0", "url": "https://omabrowser.org/oma/group/F1P5C0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SBP3-1", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "DDX20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAATTEAPAALATVEPAMPAEPAMPAEQVAGQFSASEPASLPVRSLRTAHDVGGPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGVKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMREPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKIFEEKAQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPAVCISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCHINLLLLPDPIPPGLMEECLDWDVEVEAAMHTYDLANVPTQPLKKQIQKIERTFQTRKAHGNHVASSRNTSVSALSVKSKNNTKQKLPMKSHSECGVVEKAASPEEPGSAVQLEEQMKNSVQNSVENSNNSQHHVKDASVSLPKIPCLSSFKIHLPCTLTFAELVEDYECYIKEGSERPVEIIRHYTGPGDQTVNPQNGFVRNRIPEGRVQILASSSQSGDSESDSDSYSSRTSSRSKGNKSYLEGSSDTQLKDSESVPAGGHLSKGQPLSGNATPRLAAYHDSPEIQVKARHKEGAGHNQRAKQSRRNPSRRAAGRPQPEPQEERWYGCQRETHATFPDTYQDYEEYWRAYYRAWQEYYAAASQSYYWNAQRHPGWMAAYHMNAIYLQEMMRGNQ", "length": 832 }, "evidence": [ { "id": "F1P5C0", "url": "https://omabrowser.org/oma/group/F1P5C0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JJY4-1", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "Ddx20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFEVPAALTTSESTMAAERAAAPVQAVEPTPASPWTQRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEVLANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKVPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCNINLLPLPDPIPPGLMEECLNWDVEVKAAMHTYSSPTVATQSPKKQVQKLERAFQSQRTPGNQTPSPRNTSASALSARPKHSKPKLPVKSHSECGVLEKAAPPQESGCPAQLEEQVKNSVQTSVEDSSSNSQHQAKDSSPGSLPKIPCLSSFKVHQPSTLTFAELVDDYEHYIKEGLEKPVEIIRHYTGPEAQTGNPQNGFVRNRVSEDRAQMLVSSSQSGDSESDSDSCSSRTSSQSKGNKSYLEGSSDTQLKDTECTPVGGPLSLEQVQNGNDTPTQVEYQEAPETQVKARHKEGANQRSKQSRRNPARRSSYRVQSEPQEESWYDCHRETTASFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTVYLQEMMRGNQ", "length": 825 }, "evidence": [ { "id": "F1P5C0", "url": "https://omabrowser.org/oma/group/F1P5C0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHI6-1", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "DDX20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDRQSEEQMKNSVQTPVENSTNSQHQVKEALPVSLPQIPCLSSFKIHQPYTLTFAELVEDYEHYIKEGLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVIEQRVPVLASSSQSGDSESDSDSYSSRTSSQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNGSDTPNPEKYQESPGIQMKTRLKEGASQRAKQSRRNLPRRSSFRLQTEAQEDDWYDCHREIRLSFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWNAQRHPSWMAAYHMNTIYLQEMMHSNQ", "length": 824 }, "evidence": [ { "id": "F1P5C0", "url": "https://omabrowser.org/oma/group/F1P5C0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription repressor complex", "id": "GO:0090571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090571", "evidence": [ { "database": "UniProtKB", "id": "F1P5C0", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "23680", "name": "", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNW3-1", "F1P5C0-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "R-GGA-191763", "name": "snRNP:Snurportin complex formation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5C0-1" ], "evidence": [ { "id": "R-GGA-191763", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191763" } ] }, { "id": "R-GGA-191784", "name": "snRNA Cap hypermethylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5C0-1" ], "evidence": [ { "id": "R-GGA-191784", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191784" } ] }, { "id": "R-GGA-191790", "name": "Loading and methylation of Sm proteins onto SMN Complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XMM6-1", "F1P5C0-1" ], "evidence": [ { "id": "R-GGA-191790", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191790" } ] }, { "id": "R-GGA-191830", "name": "snRNP nuclear import and release", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5C0-1" ], "evidence": [ { "id": "R-GGA-191830", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191830" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMM6", "gene_name": "PRMT5", "activity": [ { "ec_number": "2.1.1.320", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A8V0XMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMM6" } ] }, { "ec_number": "2.1.1.320", "activity": "", "evidence": [ { "id": "A0A8V0XMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMM6" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1F9", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] } ] }, { "uniprot_ac": "A0A8V0Z289", "gene_name": "DDX24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] } ] }, { "uniprot_ac": "A0A8V0Z2M8", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] } ] }, { "uniprot_ac": "A0A8V0Z5P2", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ] }, { "uniprot_ac": "A0A8V0ZC95", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] } ] }, { "uniprot_ac": "A0A8V0ZE45", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP 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phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] } ] }, { "uniprot_ac": "A0A8V0ZUQ0", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": 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"E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": 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"activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P08110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08110" } ] } ] }, { "uniprot_ac": "P37383", "gene_name": "RAD51A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P37383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37383" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] }, { "uniprot_ac": "P60706", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60706" } ] } ] }, { "uniprot_ac": "P63270", "gene_name": "ACTG2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63270", "database": "UniProtKB", 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"pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5G5" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 93, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5G5" }, { "id": "PF16211", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone H2A C-terminal", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 129, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P5V6-1", "uniprot_ac": "F1P5V6", "uniprot_id": "F1P5V6_CHICK", "mass": { "chemical_mass": 21911.0, "monoisotopic_mass": 21911.0 }, "refseq": { "ac": "NP_990490", "name": "myosin light chain 1, cardiac muscle", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" }, "gene_names": [ { "name": "MYL3", "type": "recommended", "evidence": [ { "id": "F1P5V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ] }, { "name": "MLC1c/1s", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "MLC", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "MYL3", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] } ], "protein_names": [ { "name": "Myosin, light chain 3, alkali", "type": "synonym", "evidence": [ { "id": "F1P5V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5V6/entry#names_and_taxonomy" } ] }, { "name": "cardiac muscle", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "myosin alkali light chain", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "myosin light chain 1, cardiac muscle", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "myosin light chain A1", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "myosin light chain alkali 1", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "myosin, light polypeptide 3, alkali", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "slow skeletal ventricular myosin alkali light chain 3", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "name": "ventricular, skeletal, slow", "type": "synonym", "evidence": [ { "id": "NP_990490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" }, { "id": "F1P5V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5V6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU108068.1, BU144609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000035.1. On Sep 23, 2021 this sequence version replaced NP_990490.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ] }, { "annotation": "Direct coupling of nucleotide binding to conformational changes in the N terminus of the regulatory light chain.", "evidence": [ { "database": "RefSeq", "id": "NP_990490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" }, { "database": "PubMed", "id": "15262959", "url": "https://glygen.org/publication/PubMed/15262959" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYL3", "url": "https://www.uniprot.org/uniprotkb/F1P5V6", "locus": { "chromosome": "2", "start_pos": 3447153, "end_pos": 3484338, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025568", "url": "https://www.ensembl.org/id/ENSGALG00010025568" } ] } } ], "crossref": [ { "id": "F1P5V6", "url": "https://alphafold.ebi.ac.uk/entry/F1P5V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005448", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005448", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396067", "url": "https://www.ncbi.nlm.nih.gov/gene/396067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396067", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396067", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YDRTPKC", "url": "https://omabrowser.org/oma/group/YDRTPKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P5V6", "url": "https://www.orthodb.org/?gene=F1P5V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5V6-1", "url": "https://www.uniprot.org/uniprotkb/F1P5V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKKPEPKKAPEPKKEEPKPAPKPAEPEPKKEVEFNPASIKVEFTPDQIEEFKEAFSLFDRTPKSEMKITYAQCGDVLRALGQNPTQAEVMKVLGRPKQEEMNSKMIDFETFLPMLQHISKTKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEEEVDKLMAGQEDANGCINYEAFVKHIMAN", "length": 194, "header": "tr|F1P5V6-1|F1P5V6_CHICK Isoform 1 of Myosin, light chain 3, alkali; ventricular, skeletal, slow OS=Gallus gallus OX=9031 GN=MYL3 PE=4 SV=1 CANONICAL=F1P5V6-1" }, "isoforms": [ { "isoform_ac": "F1P5V6-1", "url": "https://www.uniprot.org/uniprotkb/F1P5V6/entry#F1P5V6-1", "sequence": { "sequence": "MPPKKPEPKKAPEPKKEEPKPAPKPAEPEPKKEVEFNPASIKVEFTPDQIEEFKEAFSLFDRTPKSEMKITYAQCGDVLRALGQNPTQAEVMKVLGRPKQEEMNSKMIDFETFLPMLQHISKTKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEEEVDKLMAGQEDANGCINYEAFVKHIMAN", "length": 194, "header": "tr|F1P5V6-1|F1P5V6_CHICK Isoform 1 of Myosin, light chain 3, alkali; ventricular, skeletal, slow OS=Gallus gallus OX=9031 GN=MYL3 PE=4 SV=1 CANONICAL=F1P5V6-1" }, "locus": { "chromosome": "2", "start_pos": 3483871, "end_pos": 3452351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062381.1", "url": "https://www.ensembl.org/id/ENSGALT00010062381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038565.1", "url": "https://www.ensembl.org/id/ENSGALP00010038565.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Novel sensors of the regulatory switch on the regulatory light chain of smooth muscle Myosin.", "journal": "The Journal of biological chemistry", "date": "2004-09-17", "authors": "Mazhari Sam M, Selser Curtis T, Cremo Christine R", "evidence": [ { "database": "RefSeq", "id": "NP_990490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990490" } ], "reference": [ { "type": "PubMed", "id": "15262959", "url": "https://glygen.org/publication/PubMed/15262959" } ] } ], "pathway": [ { "id": "gga:396067", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396067", "resource": "KEGG Pathway" }, { "id": "R-GGA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GXU8-1", "protein_name": "Myosin light chain 3", "gene_name": "Myl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEDLNSKLMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEGSLLLYSSPSLGYPGGKLLCHLLLGPCLIQEIETER", "length": 203 }, "evidence": [ { "id": "F1P5V6", "url": "https://omabrowser.org/oma/group/F1P5V6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P08590-1", "protein_name": "Myosin light chain 3", "gene_name": "MYL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS", "length": 195 }, "evidence": [ { "id": "F1P5V6", "url": "https://omabrowser.org/oma/group/F1P5V6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P09542-1", "protein_name": "Myosin light chain 3", "gene_name": "Myl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS", "length": 204 }, "evidence": [ { "id": "F1P5V6", "url": "https://omabrowser.org/oma/group/F1P5V6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P16409-1", "protein_name": "Myosin light chain 3", "gene_name": "Myl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKPEPKKDDAKTAAPKAAPAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFQLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS", "length": 200 }, "evidence": [ { "id": "F1P5V6", "url": "https://omabrowser.org/oma/group/F1P5V6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P85100-1", "protein_name": "Myosin light chain 3", "gene_name": "MYL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKKPDPKKDEAKAGAKAAAAPAPAPAPPPAPEPSKEPEFDPSKIKIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAG", "length": 199 }, "evidence": [ { "id": "F1P5V6", "url": "https://omabrowser.org/oma/group/F1P5V6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cardiac muscle contraction", "id": "GO:0060048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060048", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "regulation of the force of heart contraction", "id": "GO:0002026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002026", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "regulation of striated muscle contraction", "id": "GO:0006942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006942", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue morphogenesis", "id": "GO:0055010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055010", "evidence": [ { "database": "UniProtKB", "id": "F1P5V6", "url": "https://www.uniprot.org/uniprotkb/F1P5V6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P5V6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 194, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P5V6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P5V6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F6RCI2-1", "uniprot_ac": "F6RCI2", "uniprot_id": "F6RCI2_CHICK", "mass": { "chemical_mass": 42217.0, "monoisotopic_mass": 42217.0 }, "refseq": { "ac": "NP_001020005", "name": "somatostatin receptor type 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" }, "gene_names": [ { "name": "SSTR5", "type": "recommended", "evidence": [ { "id": "F6RCI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ] }, { "name": "SS5R", "type": "synonym", "evidence": [ { "id": "NP_001020005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" } ] }, { "name": "SSTR5", "type": "synonym", "evidence": [ { "id": "NP_001020005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" } ] } ], "protein_names": [ { "name": "Somatostatin receptor 5", "type": "synonym", "evidence": [ { "id": "F6RCI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RCI2/entry#names_and_taxonomy" } ] }, { "name": "somatostatin receptor type 5", "type": "synonym", "evidence": [ { "id": "NP_001020005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.252929.1, ERR2368565.112980.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On or before Dec 8, 2021 this sequence version replaced XP_015149731.1, NP_001020005.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001020005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" } ] }, { "annotation": "The negative feedback exerted by the increasing plasma T(3) levels towards hatching is at least in part mediated by an increased expression of SSTR2 and SSTR5", "evidence": [ { "database": "RefSeq", "id": "NP_001020005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" }, { "database": "PubMed", "id": "17353013", "url": "https://glygen.org/publication/PubMed/17353013" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSTR5", "url": "https://www.uniprot.org/uniprotkb/F6RCI2", "locus": { "chromosome": "14", "start_pos": 5623056, "end_pos": 5639833, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017479", "url": "https://www.ensembl.org/id/ENSGALG00010017479" } ] } } ], "crossref": [ { "id": "ENSGALG00000005258", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005258", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15974", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15974", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427667", "url": "https://www.ncbi.nlm.nih.gov/gene/427667", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427667", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427667", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEDFQTC", "url": "https://omabrowser.org/oma/group/QEDFQTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RCI2", "url": "https://www.orthodb.org/?gene=F6RCI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24229:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24229:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001020005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RCI2-1", "url": "https://www.uniprot.org/uniprotkb/F6RCI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLYFSNAFNMDSSSSDLNSSLLTNTTENGTLSEQLPFKYIHKVLIPIFYILVCAVGLSGNTLVIYVVLRYAKMKTVTNIYILNLAVADVLFMLGLPFLATQNAISYWPFGSFLCRLVMTVDGINQFTSIFCLTVMSMDRYLAVVHPIKSTKWRRPRVAKLISMTVWTFSFLVVLPVFIFSDVQEDFHTCNMNWPEPVNIWSAAFIIYTSVLGFFGPLLVICLCYLLIVIKVKSSGIRVGSTRRRRSERKVTRMVVIIVVVFVFCWLPFYMMNIVNLIFILPEDPVLVGVYFFVVVLSYANSCANPILYGFLSDNFKQSFQKVLCLRKGNGVEDGDPIEHRQENSSRLQESMLTQRNIEFNGHMQTSKV", "length": 370, "header": "tr|F6RCI2-1|F6RCI2_CHICK Isoform 1 of Somatostatin receptor 5 OS=Gallus gallus OX=9031 GN=SSTR5 PE=3 SV=1 CANONICAL=F6RCI2-1" }, "isoforms": [ { "isoform_ac": "F6RCI2-1", "url": "https://www.uniprot.org/uniprotkb/F6RCI2/entry#F6RCI2-1", "sequence": { "sequence": "MDPLYFSNAFNMDSSSSDLNSSLLTNTTENGTLSEQLPFKYIHKVLIPIFYILVCAVGLSGNTLVIYVVLRYAKMKTVTNIYILNLAVADVLFMLGLPFLATQNAISYWPFGSFLCRLVMTVDGINQFTSIFCLTVMSMDRYLAVVHPIKSTKWRRPRVAKLISMTVWTFSFLVVLPVFIFSDVQEDFHTCNMNWPEPVNIWSAAFIIYTSVLGFFGPLLVICLCYLLIVIKVKSSGIRVGSTRRRRSERKVTRMVVIIVVVFVFCWLPFYMMNIVNLIFILPEDPVLVGVYFFVVVLSYANSCANPILYGFLSDNFKQSFQKVLCLRKGNGVEDGDPIEHRQENSSRLQESMLTQRNIEFNGHMQTSKV", "length": 370, "header": "tr|F6RCI2-1|F6RCI2_CHICK Isoform 1 of Somatostatin receptor 5 OS=Gallus gallus OX=9031 GN=SSTR5 PE=3 SV=1 CANONICAL=F6RCI2-1" }, "locus": { "chromosome": "14", "start_pos": 5625101, "end_pos": 5623992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042222.1", "url": "https://www.ensembl.org/id/ENSGALT00010042222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024740.1", "url": "https://www.ensembl.org/id/ENSGALP00010024740.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Feedback control of thyrotropin secretion in the chicken: thyroid hormones increase the expression of hypophyseal somatostatin receptor types 2 and 5.", "journal": "General and comparative endocrinology", "date": "2007", "authors": "De Groef Bert, Grommen Sylvia V H, Darras Veerle M", "evidence": [ { "database": "RefSeq", "id": "NP_001020005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020005" } ], "reference": [ { "type": "PubMed", "id": "17353013", "url": "https://glygen.org/publication/PubMed/17353013" } ] } ], "pathway": [ { "id": "gga:427667", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427667", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRE5-1", "protein_name": "Somatostatin receptor 5", "gene_name": "SSTR5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPLFPATPPTSWNTSWAATSRGGGGGGGGENGTLAEPVPSPGARAVAVPVLYLLVCALGLGGNALVIYVVLRHAKMKTVTNIYILNLAVADVLLMLGLPFVATQNALSYWPFGPVLCRLVMTLDGINQFTSIFCLTVMSVDRYLAVVHPLRSARWRRPRVARLASAAVWAFSLVMSLPLVVFADVQEGWNTCNLSWPEPVGLWGAVFIIYTSVLGFFGPLLVICLCYLLIVVKLKASGVRVGSTRRRSERKVTRMVVVVVLVFVGCWLPFFIANLVNLAFVLPEEPASAGAYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRKGSGVEDANATKPRAGQSGRPPEAPVALRSHEANGLMQTSRL", "length": 371 }, "evidence": [ { "id": "F6RCI2", "url": "https://omabrowser.org/oma/group/F6RCI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MV99-1", "protein_name": "Somatostatin receptor type 5", "gene_name": "SSTR5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPLFPASPLTTWNTSSVVPSGSGDENGTLAGLGPSPGARAVVVPVLYLLVCAVGLGGNTLVIYVVLRHAKMKTVTNIYILNLAVADVLLMLGLPFVATQNAISYWPFGPVLCRLVMTLDGINQFTSIFCLTVMSVDRYLAVVHPIRSARWRRPRVAKLASAAVWAFSLVMSLPLVVFADIQEGWNTCNLSWPEPVGLWGAVFIIYTSVLGFFGPLLVICLCYLLIVVKLKASGVRVGSTRRRSERKVTRMVVVVVLVFAGCWLPFFIVNIVNLAFALPEEPASAGAYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRKGYGAGAEDADATEPQPGPSSRLQEAMMPVRSCKANGLMQTSKL", "length": 368 }, "evidence": [ { "id": "F6RCI2", "url": "https://omabrowser.org/oma/group/F6RCI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HBW1-1", "protein_name": "Somatostatin receptor type 5", "gene_name": "Sstr5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPLFPASTPIWNASAASSSNHNWSLVSPVSSMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRHAKMKTVTNVYILNLAVADVLLMLGLPFLATQNAVSYWPFGPFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVELWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGVRVGSSRRRRSERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPASAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQATLPTRSCDANGLMQTSRL", "length": 362 }, "evidence": [ { "id": "F6RCI2", "url": "https://omabrowser.org/oma/group/F6RCI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08858-1", "protein_name": "Somatostatin receptor type 5", "gene_name": "Sstr5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPLSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKALCLRRGYGVEDADAIEPRPDKSGRPQTTLPTRSCEANGLMQTSRL", "length": 362 }, "evidence": [ { "id": "F6RCI2", "url": "https://omabrowser.org/oma/group/F6RCI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P30938-1", "protein_name": "Somatostatin receptor type 5", "gene_name": "Sstr5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL", "length": 364 }, "evidence": [ { "id": "F6RCI2", "url": "https://omabrowser.org/oma/group/F6RCI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "somatostatin receptor activity", "id": "GO:0004994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004994", "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "pmid": "" }, { "name": "neuropeptide binding", "id": "GO:0042923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042923", "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "F6RCI2", "url": "https://www.uniprot.org/uniprotkb/F6RCI2" } ], "pmid": "" }, { "name": "regulation of insulin 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F7AVB9-1", "uniprot_ac": "F7AVB9", "uniprot_id": "F7AVB9_CHICK", "mass": { "chemical_mass": 36466.0, "monoisotopic_mass": 36466.0 }, "refseq": { "ac": "XP_004936519", "name": "potassium channel subfamily K member 16 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936519" }, "gene_names": [ { "name": "KCNK4", "type": "recommended", "evidence": [ { "id": "F7AVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F7AVB9" } ] }, { "name": "KCNK4", "type": "synonym", "evidence": [ { "id": "XP_004936519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936519" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 4", "type": "synonym", "evidence": [ { "id": "F7AVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F7AVB9/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 16 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004936519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936519" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936519" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F7AVB9", "url": "https://www.uniprot.org/uniprotkb/F7AVB9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK4", "url": "https://www.uniprot.org/uniprotkb/F7AVB9", "locus": {} } ], "crossref": [ { "id": "F7AVB9", "url": "https://alphafold.ebi.ac.uk/entry/F7AVB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012021", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423536", "url": "https://www.ncbi.nlm.nih.gov/gene/423536", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423536", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423536", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F7AVB9", "url": "https://www.orthodb.org/?gene=F7AVB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936519", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F7AVB9", "url": "https://www.uniprot.org/uniprotkb/F7AVB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7AVB9-1", "url": "https://www.uniprot.org/uniprotkb/F7AVB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSGKLQTGLLVGSYFVYLLVGAAVFQALERTAEKQQKMAAAQMKEAFLQNFTHLTVAEMEQFMKNLTEAIQNGVYPIGNESQTENSNWDFSNSFFFAGTVVSTIGYGTLRPKTVGGQIFCVFFALFGIPLNIVFLHRVGKILSLLCKKLGKFLYEKGMRKKKIKFLTLLFFLVTGILVFLCLPSLFFQITEGWSYSEGIYFAFITLSTIGFGDYVVGKQPGRIYFSYYRTLVAIWILFGLAWIALLFNLLTTVLEDTEKIIVKDLHQIGKVGEDNAASQPRRCWPVQFIPEEELISPHAEGDAQKMETLAAEGAQENGVSSSRF", "length": 325, "header": "tr|F7AVB9-1|F7AVB9_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 4 OS=Gallus gallus OX=9031 GN=KCNK4 PE=3 SV=3 CANONICAL=F7AVB9-1" }, "isoforms": [ { "isoform_ac": "F7AVB9-1", "url": "https://www.uniprot.org/uniprotkb/F7AVB9/entry#F7AVB9-1", "sequence": { "sequence": "MCSGKLQTGLLVGSYFVYLLVGAAVFQALERTAEKQQKMAAAQMKEAFLQNFTHLTVAEMEQFMKNLTEAIQNGVYPIGNESQTENSNWDFSNSFFFAGTVVSTIGYGTLRPKTVGGQIFCVFFALFGIPLNIVFLHRVGKILSLLCKKLGKFLYEKGMRKKKIKFLTLLFFLVTGILVFLCLPSLFFQITEGWSYSEGIYFAFITLSTIGFGDYVVGKQPGRIYFSYYRTLVAIWILFGLAWIALLFNLLTTVLEDTEKIIVKDLHQIGKVGEDNAASQPRRCWPVQFIPEEELISPHAEGDAQKMETLAAEGAQENGVSSSRF", "length": 325, "header": "tr|F7AVB9-1|F7AVB9_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 4 OS=Gallus gallus OX=9031 GN=KCNK4 PE=3 SV=3 CANONICAL=F7AVB9-1" }, "locus": { "chromosome": "5", "start_pos": 54557500, "end_pos": 54547940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041655.1", "url": "https://www.ensembl.org/id/ENSGALT00010041655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024366.1", "url": "https://www.ensembl.org/id/ENSGALP00010024366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423536", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": 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The reference sequence was derived from JAENSK010000251.1. 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "H9KYW9-1", "uniprot_ac": "H9KYW9", "uniprot_id": "H9KYW9_CHICK", "mass": { "chemical_mass": 41088.0, "monoisotopic_mass": 41088.0 }, "refseq": { "ac": "XP_423393", "name": "vacuolar protein sorting-associated protein 72 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423393" }, "gene_names": [ { "name": "VPS72", "type": "recommended", "evidence": [ { "id": "H9KYW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ] }, { "name": "VPS72", "type": "synonym", "evidence": [ { "id": "XP_423393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423393" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 72 homolog", "type": "recommended", "evidence": [ { "id": "H9KYW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KYW9/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor-like 1", "type": "synonym", "evidence": [ { "id": "H9KYW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KYW9/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 72 homolog", "type": "synonym", "evidence": [ { "id": "XP_423393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423393" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_423393.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423393" } ] }, { "annotation": "Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9#function" }, { "database": "UniProtKB", "id": "ARBA00002050", "url": "https://www.uniprot.org/uniprotkb/ARBA00002050#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VPS72", "url": "https://www.uniprot.org/uniprotkb/H9KYW9", "locus": { "chromosome": "25", "start_pos": 2638860, "end_pos": 2642493, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028599", "url": "https://www.ensembl.org/id/ENSGALG00010028599" } ] } } ], "crossref": [ { "id": "H9KYW9", "url": "https://alphafold.ebi.ac.uk/entry/H9KYW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000793", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000793", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425660", "url": "https://www.ncbi.nlm.nih.gov/gene/425660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGPTIRY", "url": "https://omabrowser.org/oma/group/TGPTIRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "H9KYW9", "url": "https://www.orthodb.org/?gene=H9KYW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13275:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13275:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9KYW9-1", "url": "https://www.uniprot.org/uniprotkb/H9KYW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLAEGRAPRRTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYRGDQSDSDDEVDSDFDIDEGEEPTSDQDESEPKRRRRVVTKAYREPIKSLRPKKADTPSSSSQKAREVKSAPLELQDEVADSRKHMRQSTTEHTRQTFLRIQERQVQSKRKKGGPNYDRPLTQEELLEEAKITEEINLRSLENYERLEADKKKQVQKKRKCVGPVIRYWSVTMPLITELGKEENVDVEGLDQDPQQADAAPAAAPACSGKCSRTFISFSDDETFERFFPKAKAPRLPVREICPVTHKPAVYRDPITDIPYSNIRAFKIIREAYKKYITAHGLPSAAAASAALGAAPPGPDPSLRATRQKIIIKQSVPTA", "length": 365, "header": "tr|H9KYW9-1|H9KYW9_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 72 homolog OS=Gallus gallus OX=9031 GN=VPS72 PE=1 SV=2 CANONICAL=H9KYW9-1" }, "isoforms": [ { "isoform_ac": "H9KYW9-1", "url": "https://www.uniprot.org/uniprotkb/H9KYW9/entry#H9KYW9-1", "sequence": { "sequence": "MSLAEGRAPRRTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYRGDQSDSDDEVDSDFDIDEGEEPTSDQDESEPKRRRRVVTKAYREPIKSLRPKKADTPSSSSQKAREVKSAPLELQDEVADSRKHMRQSTTEHTRQTFLRIQERQVQSKRKKGGPNYDRPLTQEELLEEAKITEEINLRSLENYERLEADKKKQVQKKRKCVGPVIRYWSVTMPLITELGKEENVDVEGLDQDPQQADAAPAAAPACSGKCSRTFISFSDDETFERFFPKAKAPRLPVREICPVTHKPAVYRDPITDIPYSNIRAFKIIREAYKKYITAHGLPSAAAASAALGAAPPGPDPSLRATRQKIIIKQSVPTA", "length": 365, "header": "tr|H9KYW9-1|H9KYW9_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 72 homolog OS=Gallus gallus OX=9031 GN=VPS72 PE=1 SV=2 CANONICAL=H9KYW9-1" }, "locus": { "chromosome": "25", "start_pos": 2641100, "end_pos": 2638956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069261.1", "url": "https://www.ensembl.org/id/ENSGALT00010069261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042703.1", "url": "https://www.ensembl.org/id/ENSGALP00010042703.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425660", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4J5-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "VPS72", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGETEEPRRKRRVVTKAYKEPLKSLRPRKVSTPAGSSQKTREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDVEGLDPTPTASALTPRPGTGPVVPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK", "length": 364 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MFL1-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "Vps72", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVSTPASSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPVITYHSVTVPLVGEPGPKEENVDVEGLDPAPTASALTAHAGSGPAVPPAHCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPAASALGPGPPPPEPLPGSGPRALRQKIVIK", "length": 364 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1WC45-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "Vps72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDVEGLDPAPTSSALTAHAGTGPAVPPPHCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGAGPRALRQKIVIK", "length": 364 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4IP06-1", "protein_name": "SWR1 complex subunit 2", "gene_name": "SWC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEIDEEEPMVFLDRTTRATRGKRMTKLLDDEVEEDEQFWNQEALKEEEHDDEYEAEREVADEFDSDFNDDEPEPDAVAVNEKELRDLPKKRLIYPGKTASKKKKKKTKVVSQLEYIPGDEKPGEELGNKEQEEKEENEAQEDMEGEKVIRKSTRTSVVVRQAERDALRAAIQATTKPIQRKKVGEEKRMTQEEMLLEAAQTEIMNLRNLERVLAREEEVKKKAIVHKAVYKGPQIRYHSKDGCNYLEFCNGASFNSELSTKSVPYPEKAVCVITGLPAKYRDPKTGLPYATRDAFKAIRERFMDEHDGLRKKMEMGDLFDTLVAKGFATKQKRTKIPKSNKSFSLRSSARFLSSESEEESEEDSD", "length": 365 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q15906-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "VPS72", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK", "length": 364 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9F6-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "VPS72", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEKEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVSTPAGSSQKTREEKALLPLELQDDGTDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDVEGLDPAPMASALAARAGTGPVIPPARCSRTFITFSDDATFEEWFPQGRTPKIPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK", "length": 364 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62481-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "Vps72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDVEGLDPAPTASALAPHAGTGTGAAAATPPAHCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK", "length": 368 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKM6-1", "protein_name": "Vacuolar protein sorting-associated protein 72 homolog", "gene_name": "YL-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAASRSRRNNAGNKIAHLLNEEEEDDFYKTSYGGFQEDEEDKEYEQKDEEEDVVDSDFSIDENDEPVSDQEEAPEKKRKRGVVNTKAYKETKPAVKKETKATPALHKKRPGGGVTKRRPRPRFTVLDSGRKSIRTSTAIKTQATKIRLKELDDARKRKKKKVRVEDYMPTQEELLEEAKITEEENTKSLEKFQKMELEKKKSRPTKRTFSGPTIRYHSLTMPAMRKPTRGANPAVDSKDLAGKCERTFVTIENDFNDKVFQSLFRHKAPPKASNGICPITRLPARYFDPITQQPYYSIQAFKILREAYYMQLEQQGGGSEQPELAKWLEWRKLVKENRLKASAAASKNGDN", "length": 351 }, "evidence": [ { "id": "H9KYW9", "url": "https://omabrowser.org/oma/group/H9KYW9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "H9KYW9", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-H9KYW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 365, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-H9KYW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/H9KYW9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "H9KYW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KYW9" }, { "id": "SM00993", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00993" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vps72/YL1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 315, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "H9KZZ2-1", "uniprot_ac": "H9KZZ2", "uniprot_id": "H9KZZ2_CHICK", "mass": { "chemical_mass": 149785.0, "monoisotopic_mass": 149785.0 }, "refseq": { "ac": "XP_015153913", "name": "insulin receptor-related protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153913" }, "gene_names": [ { "name": "INSRR", "type": "recommended", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "name": "INSRR", "type": "synonym", "evidence": [ { "id": "XP_015153913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153913" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase receptor", "type": "recommended", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.1", "type": "synonym", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2/entry#names_and_taxonomy" } ] }, { "name": "insulin receptor-related protein", "type": "synonym", "evidence": [ { "id": "XP_015153913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153913" } ] }, { "annotation": "Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2#function" }, { "database": "UniProtKB", "id": "ARBA00055220", "url": "https://www.uniprot.org/uniprotkb/ARBA00055220#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INSRR", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2", "locus": { "chromosome": "25", "start_pos": 1076030, "end_pos": 1066760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027350", "url": "https://www.ensembl.org/id/ENSGALG00010027350" } ] } } ], "crossref": [ { "id": "ENSGALG00000013253", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857811", "url": "https://www.ncbi.nlm.nih.gov/gene/100857811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857811", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQRGHVY", "url": "https://omabrowser.org/oma/group/IQRGHVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "H9KZZ2", "url": "https://www.orthodb.org/?gene=H9KZZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416:SF338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9KZZ2-1", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGALGVLRLLLALLLLGPLLLPPVQAPSEICGSMDIRNDVSQLQKLENCSIIEGNLQILLMFTTGAEDFRGLSFPRLLMITEYLLLFRVYGLESLRDLFPNLSVIRGTNLFFNYALVIFEMPHLREIGLHSLGHVLRGSVRIERNQELCHLSTIDWGLLLPDAVDNSYIVGNKLAEECADVCPGILDVEKPCAQTVVNGQLDYRCWTSSYCQKVCPCGAGSACTASGECCHAECLGGCGRPRDSRSCVACRHFHFNGHCLPSCPPRTYEYEGWRCITAEYCASLRKVSDNPRDASKFVIHQQQCLSECPPGYTRNESSIFCHKCEGLCPKACKVGTKTVDSTRAAQELAGCTLVEGNLILNIRRGYNLASELQSSLGLIETITGFLKIKHSFALVSLSFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLWDWSHHVLSIPVGKMYFAFNPKLCLAEIYHMEEVTGTKGRQNKAEINPRTNGDRASCKTQTLRFISNITESDRIFLKWERYHPPEYRDLLSFIVYYKESPFQNVSEYVGQDACGAQSWNVLDVDLPLSSEQEPGVALLNLRPWTQYAIFVRAITLTTAEEGRNYGAQSEVVYIRTMPAAPTVPRDVISMSNSSSHIVVRWKPPTQRNGNITYYLVLWQQLAEDMELYINDYCHKGLKLPTSSADTRFSYGDGPEVEQDAEERCCPCSPADGQLRMEGEAESFQKKFENFLHNSIIIPRPPWKVTSINKYPQRSPKRRRDLAAVTSPTDASSVEPPPPSHTGAEPKPDFQIFEDKVVRDRVVLSRLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPELQADNIPGNVTWEPASKNSVLLRWQEPRNPNGLILKYEIKYSRESEEVTTVVCVSRHRYAKYGGVHLALLQPGNYSAKVRATSLAGNGSWTGLVKFYILGPAEEESGSFYILLTVTPVVLMVLISCLAVFVFFYNKKRSNDGYPSGTLYASVNPEYFSASDMYIPDEWEVSREKITVIRELGQGSFGMVYEGLAMGLVAEGEETKVALKTVNELATMRERIEFLKEASVMKAFKCHHVVRLLGVVSQGQPALVIMELMTRGDLKSYLRSLRPDAENNPGLPPPSLKDMIQMAGEIADGMAYLNAKKFVHRDLAARNCMVSEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPEALKDGIFNTQSDVWSFGVVLWEITTLAEQPYQGMSNEQVLHYVMDNGVLERPENCPDQLHELMCLCWQQNPRQRPSFVQLLESIKEHMAPAFRTLSFFYSPENRRRGSSEPSDGETEQPPEEDEPPAPPLPTRKGRGRLPNGTGCL", "length": 1333, "header": "tr|H9KZZ2-1|H9KZZ2_CHICK Isoform 1 of Tyrosine-protein kinase receptor OS=Gallus gallus OX=9031 GN=INSRR PE=3 SV=3 CANONICAL=H9KZZ2-1" }, "isoforms": [ { "isoform_ac": "H9KZZ2-1", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2/entry#H9KZZ2-1", "sequence": { "sequence": "MGALGVLRLLLALLLLGPLLLPPVQAPSEICGSMDIRNDVSQLQKLENCSIIEGNLQILLMFTTGAEDFRGLSFPRLLMITEYLLLFRVYGLESLRDLFPNLSVIRGTNLFFNYALVIFEMPHLREIGLHSLGHVLRGSVRIERNQELCHLSTIDWGLLLPDAVDNSYIVGNKLAEECADVCPGILDVEKPCAQTVVNGQLDYRCWTSSYCQKVCPCGAGSACTASGECCHAECLGGCGRPRDSRSCVACRHFHFNGHCLPSCPPRTYEYEGWRCITAEYCASLRKVSDNPRDASKFVIHQQQCLSECPPGYTRNESSIFCHKCEGLCPKACKVGTKTVDSTRAAQELAGCTLVEGNLILNIRRGYNLASELQSSLGLIETITGFLKIKHSFALVSLSFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLWDWSHHVLSIPVGKMYFAFNPKLCLAEIYHMEEVTGTKGRQNKAEINPRTNGDRASCKTQTLRFISNITESDRIFLKWERYHPPEYRDLLSFIVYYKESPFQNVSEYVGQDACGAQSWNVLDVDLPLSSEQEPGVALLNLRPWTQYAIFVRAITLTTAEEGRNYGAQSEVVYIRTMPAAPTVPRDVISMSNSSSHIVVRWKPPTQRNGNITYYLVLWQQLAEDMELYINDYCHKGLKLPTSSADTRFSYGDGPEVEQDAEERCCPCSPADGQLRMEGEAESFQKKFENFLHNSIIIPRPPWKVTSINKYPQRSPKRRRDLAAVTSPTDASSVEPPPPSHTGAEPKPDFQIFEDKVVRDRVVLSRLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPELQADNIPGNVTWEPASKNSVLLRWQEPRNPNGLILKYEIKYSRESEEVTTVVCVSRHRYAKYGGVHLALLQPGNYSAKVRATSLAGNGSWTGLVKFYILGPAEEESGSFYILLTVTPVVLMVLISCLAVFVFFYNKKRSNDGYPSGTLYASVNPEYFSASDMYIPDEWEVSREKITVIRELGQGSFGMVYEGLAMGLVAEGEETKVALKTVNELATMRERIEFLKEASVMKAFKCHHVVRLLGVVSQGQPALVIMELMTRGDLKSYLRSLRPDAENNPGLPPPSLKDMIQMAGEIADGMAYLNAKKFVHRDLAARNCMVSEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPEALKDGIFNTQSDVWSFGVVLWEITTLAEQPYQGMSNEQVLHYVMDNGVLERPENCPDQLHELMCLCWQQNPRQRPSFVQLLESIKEHMAPAFRTLSFFYSPENRRRGSSEPSDGETEQPPEEDEPPAPPLPTRKGRGRLPNGTGCL", "length": 1333, "header": "tr|H9KZZ2-1|H9KZZ2_CHICK Isoform 1 of Tyrosine-protein kinase receptor OS=Gallus gallus OX=9031 GN=INSRR PE=3 SV=3 CANONICAL=H9KZZ2-1" }, "locus": { "chromosome": "25", "start_pos": 1075693, "end_pos": 1066959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066309.1", "url": "https://www.ensembl.org/id/ENSGALT00010066309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040575.1", "url": "https://www.ensembl.org/id/ENSGALP00010040575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:100857811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857811", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MC23-1", "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "INSRR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVPSLWPWVACLLAILLSLGFGLDTREVCPSLDIRSDVAELRRLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGARLFLGYALVIFEMPHMRDVGLPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPSPGANHIVGNKLGEECADVCPGLLGTTGEPCARTTFSGHTDYRCWTSSHCQKVCPCPRGLACTVRGECCHAECLGGCSRPEDPRACVACRHLYFQGACHRACPPGTYQHESWRCVTAERCASLRSVPGRASTFGIHQGSCLAQCPPGFTRNDSSIFCHKCEGLCPKECKVGTKTIDSVQAAQDLVGCTHVEGSLILNLRQGYNLELELQRSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDTMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTKGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEANRILLRWERYEPLEARDLLSFIVYYKESPFQNATEYIGPDACGAQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNITYYLVLWQRLAEDSDLYLNDYCHRGLRLPTSNNDPRFDGEDGELEADREPGCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPKSPWKVTSINKSPQRDSGRSRRAAEALRLGGNSSDFKIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEAASKSSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYIPGPEEEDSGGLHVLLTVTPAGLMLLIILAVLGFFYSKKRNSTLYASVNPEYFSASHMYIPDEWEVPREQISIIRELGQGSFGMVYEGLAQGLEVGEEPTPVALKTVNELASPRERIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVVDGGVLEELESCPVQLQELMQRCWQQNPRLRPTFTHILDSIQEELRPSFRLLSFYHSPECRGARASLLPTDAEPDSPRTPKEASSDFSPQNGGPGH", "length": 1301 }, "evidence": [ { "id": "H9KZZ2", "url": "https://omabrowser.org/oma/group/H9KZZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P14616-1", "protein_name": "Insulin receptor-related protein", "gene_name": "INSRR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPSLWPWGACLPVIFLSLGFGLDTVEVCPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACRHLYFQGACLWACPPGTYQYESWRCVTAERCASLHSVPGRASTFGIHQGSCLAQCPSGFTRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRNRTLYASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELRPSFRLLSFYYSPECRGARGSLPTTDAEPDSSPTPRDCSPQNGGPGH", "length": 1297 }, "evidence": [ { "id": "H9KZZ2", "url": "https://omabrowser.org/oma/group/H9KZZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64716-1", "protein_name": "Insulin receptor-related protein", "gene_name": "Insrr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPALWPWGVYLLMSLLSLGSCLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGARLFLGYALIIFEMPHLRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACTVGGECCHSECLGGCSQPEDPRACVACRHLYFQGVCLPTCPPGTYQYESWRCVTAELCGHLREVPGHATAFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGSLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRRETGLLRLGKNNSDFEIHEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVVWKAVGKSSVILHWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVAFYITGPEEEDTGGLRILLTVTPVGFMLLVMLAALGFFYSKKRNSTLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHILDRIQDELRPSFRLCSFYYSPECQRGQASLLPTEAEPDSPPTLNGASDYGPPNGDPGH", "length": 1300 }, "evidence": [ { "id": "H9KZZ2", "url": "https://omabrowser.org/oma/group/H9KZZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VJ04-1", "protein_name": "Protein CG10702", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHCGNMLLGVGLMFLALYVPCAESKKEHECTSIDIRNECKNMHLLDNCTVVTGYVMITLITIEQRCNFSEYSYPLLTEITEFMIFTDVRGLVNITEMFPHLTVIRGRRLFLNYALGVTNMHELEQLVFPKLVAIQRGQVYIGSCPKLCSIGRVNWDLLTLTRGENNIIMVNKNCSTPVCSGCSSSHCWSNHYCQRSINENVANPKANINACHEECLGGCKNNSSSPADCSVCRGLSDDGVCVKSCPKDKYVMENYQRCYTKAECVLKHGYVISGSQCVAFCPSGYKTNNRSECVLCSPDEACISFCTPEWPGKAFTVYNLADAENLRGCQIFNGSLVITIRNKVNETQLYQSFTSMREVRGHVKVYRSSQLRSLQFLRNLERVHGDPLENRHYSFILYDNKELSELWTPSRQLEFMEGGMFMHRNNKLCNRRMREFQNAVTHDRALDSLQTNDQEVQCSPLKLQLYVQKRTHRSVKLSWLKSQTSQKIELIHRPLLPGKLYHEESELDAPICTRINWKRRLLFPDDLIENGTHYLFDLDDLQPDTRYVVLLRTFGNDEAHEAYEARSELTYVQTELDIPKPPLLELVKKTDSSLTVQMASHDHVSFLLTVFELSDDQDYIEQRNYCHQPSYVWQDMDGPRWMAYEDYDDCCAQKAEQFEDSRFIADMREQYRCTLDDREQCRRLAHTEVSLPQLRLPGNTTEYELKALHRYRLYALQLQACNPLGCSSHTTLYGRTNYTMGADLLTQLYACHIPEMDKYIMRFEEPKKPNGLVTNYVIHFRNNFSQTHVGCVTRMDHQSAGYMYVKQINITFTECAVRVHSLAGDVMTPYMPISLCSDEDRLQAFHSREAKDLSPEITDLPATASHGRGISIFLICFLFGCSVSLVWVLYKRRCWRKLPGLRRYVPVREQWLRDRQQTEDREILVDGFETVRFQNNNNSQADDYPM", "length": 946 }, "evidence": [ { "id": "H9KZZ2", "url": "https://omabrowser.org/oma/group/H9KZZ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTL4-1", "protein_name": "Insulin receptor-related protein", "gene_name": "Insrr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPALWPWGVHLLMSLLSLGSGLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLTVIRGTRLFLGYALIIFEMPHLRDVGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGTNHIVGNKLGEECADVCPGVLGAAGEPCSRTTFSGRTDYRCWTSSHCQKVCPCPRGMACTAGGDCCHSECLGGCSQPEDPRACVACRHLYFQGVCLRACPPGTYQYESWRCVTAELCAHLREVPGLATTFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGNLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVTAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRREAGLLRLGKNNSDFEIQEDKVPRERAILSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWKAAGKSSVTLHWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVTFYITDLEEEDTGGMRIFLTVTPVGFMLLVTLAALGFFYSRKRNSTLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHILDRIQDELRPSFRLCSFYYSPECQRGQASLLPTEAEPDSPPTLNGASDYSAPNGGPGH", "length": 1300 }, "evidence": [ { "id": "H9KZZ2", "url": "https://omabrowser.org/oma/group/H9KZZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "insulin receptor activity", "id": "GO:0005009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005009", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "insulin receptor substrate binding", "id": "GO:0043560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043560", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to alkaline pH", "id": "GO:0071469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071469", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" }, { "name": "insulin receptor complex", "id": "GO:0005899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005899", "evidence": [ { "database": "UniProtKB", "id": "H9KZZ2", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1328, "end_pos": 1330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", 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O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ 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[ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", 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O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9PUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PUF6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q9PUF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PUF6" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] }, { "uniprot_ac": "R4GJW5", "gene_name": "WEE1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "R4GJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJW5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.1", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.10.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1" }, { "id": "2.7.10.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 1328, "end_pos": 1330 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 620, "end_pos": 622 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "H9L019-1", "uniprot_ac": "H9L019", "uniprot_id": "H9L019_CHICK", "mass": { "chemical_mass": 43923.0, "monoisotopic_mass": 43923.0 }, "refseq": { "ac": "XP_423721", "name": "splicing factor 3B subunit 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423721" }, "gene_names": [ { "name": "SF3B4", "type": "recommended", "evidence": [ { "id": "H9L019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ] }, { "name": "SF3B4", "type": "synonym", "evidence": [ { "id": "XP_423721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423721" } ] } ], "protein_names": [ { "name": "Splicing factor 3B subunit 4", "type": "recommended", "evidence": [ { "id": "H9L019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L019/entry#names_and_taxonomy" } ] }, { "name": "splicing factor 3B subunit 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_423721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423721" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_423721.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423721" } ] }, { "annotation": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3B4 is part of the SF3B subcomplex, which is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence in pre-mRNA. Sequence independent binding of SF3A and SF3B subcomplexes upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019#function" }, { "database": "UniProtKB", "id": "ARBA00053340", "url": "https://www.uniprot.org/uniprotkb/ARBA00053340#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SF3B4", "url": "https://www.uniprot.org/uniprotkb/H9L019", "locus": { "chromosome": "25", "start_pos": 684367, "end_pos": 676515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028887", "url": "https://www.ensembl.org/id/ENSGALG00010028887" } ] } } ], "crossref": [ { "id": "H9L019", "url": "https://alphafold.ebi.ac.uk/entry/H9L019", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013352", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013352", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12335", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12335", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426042", "url": "https://www.ncbi.nlm.nih.gov/gene/426042", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AMVYEIM", "url": "https://omabrowser.org/oma/group/AMVYEIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "H9L019", "url": "https://www.orthodb.org/?gene=H9L019", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48030", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48030", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48030:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48030:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_423721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L019-1", "url": "https://www.uniprot.org/uniprotkb/H9L019-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSVPTPVVTALGPGVTPPGLPPPGSFPPPVPPPGAMPPGMPPAMPPPPMPPGAGAPGPPTGAAPTGGHPPHPHAFPPGGMHHPGMPPMQVHHGPPGMGQHHPGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPHFGSPMGHPGPMPHHGMRGPPPLMPPHGYNGPPRPPPYGYQRVPLPPRPAQRPPGVPPRGPLRGPLP", "length": 418, "header": "tr|H9L019-1|H9L019_CHICK Isoform 1 of Splicing factor 3B subunit 4 OS=Gallus gallus OX=9031 GN=SF3B4 PE=1 SV=3 CANONICAL=H9L019-1" }, "isoforms": [ { "isoform_ac": "H9L019-1", "url": "https://www.uniprot.org/uniprotkb/H9L019/entry#H9L019-1", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSVPTPVVTALGPGVTPPGLPPPGSFPPPVPPPGAMPPGMPPAMPPPPMPPGAGAPGPPTGAAPTGGHPPHPHAFPPGGMHHPGMPPMQVHHGPPGMGQHHPGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPHFGSPMGHPGPMPHHGMRGPPPLMPPHGYNGPPRPPPYGYQRVPLPPRPAQRPPGVPPRGPLRGPLP", "length": 418, "header": "tr|H9L019-1|H9L019_CHICK Isoform 1 of Splicing factor 3B subunit 4 OS=Gallus gallus OX=9031 GN=SF3B4 PE=1 SV=3 CANONICAL=H9L019-1" }, "locus": { "chromosome": "25", "start_pos": 681431, "end_pos": 676542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069868.1", "url": "https://www.ensembl.org/id/ENSGALT00010069868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042994.1", "url": "https://www.ensembl.org/id/ENSGALP00010042994.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MWR2-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "SF3B4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "length": 424 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SDG0-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "SF3B4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPSAGTPGAGHPAHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "length": 424 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H2U6-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "Sf3b4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "length": 424 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15427-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "SF3B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "length": 424 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NWB3-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "sf3b4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSMPTPVMTALGAAMPIPGMPPPGAFPPVPPPGTMPPGMPPGMPMPPAPGTPAPQGGGGPPPGHPPFPPAGMHPPGMPHMPMPPTGPPGMVPPPPGPPGSNQPRAPPPPQMPPPPMGVPPRGPFGPPMGPPMHPGMRGPPPPMPPPGYGAGPPRPPPFGFQRGPPMPPRPPAPRGPMRAPAPS", "length": 400 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8QZY9-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "Sf3b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "length": 424 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W424-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "Spx", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAGPIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMIKLYGKPIRVNKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFKKDHKGERHGSAAERLLAAQNPSTHADRPHQLFADAPVQTMMPQMPGQIPAQMPGQMMPPPMMAPPPPVVPVSNNNMGMLAPPPPVPQPAPFPATIPPPPLPPMTGGQPPLPPAMGIPPPPRMMQPNAWAPPGMPAPPPRPPPTNWRPPPVPFPPTPYARPYQPDGYQY", "length": 347 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZU66-1", "protein_name": "Splicing factor 3B subunit 4", "gene_name": "EMB2444", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTTRIAPGVGANLLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVPKDRVTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLDVGANLFIGNLDPDVDEKLLYDTFSAFGVIASNPKIMRDPDTGNSRGFGFISYDSFEASDAAIESMTGQYLSNRQITVSYAYKKDTKGERHGTPAERLLAATNPTAQKSRPHTLFAMGPPSSAPQVNGLPRPFANGSMQPVPIPAPRQPPPPPPQVYQTQPPSWPSQPQQHSMVPPPMQFRPPQGMPPPPPPQFLNHQQGFGGPRPPPPPQAMGMHQHGGWPPQHMQQQGGPPQQQQPPYQHHHMSMPPPPPHQG", "length": 363 }, "evidence": [ { "id": "H9L019", "url": "https://omabrowser.org/oma/group/H9L019/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" }, { "name": "splicing factor binding", "id": "GO:1990935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990935", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "H9L019", "url": "https://www.uniprot.org/uniprotkb/H9L019" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-H9L019-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 418, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-H9L019-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/H9L019" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "H9L019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9L019" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 91, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 233, 282 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "O13113-1", "uniprot_ac": "O13113", "uniprot_id": "DAD1_CHICK", "mass": { "chemical_mass": 12926.0, "monoisotopic_mass": 12926.0 }, "refseq": { "ac": "NP_001007474", "name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" }, "gene_names": [ { "name": "DAD1", "type": "recommended", "evidence": [ { "id": "O13113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13113" } ] }, { "name": "DAD1", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] } ], "protein_names": [ { "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "type": "recommended", "evidence": [ { "id": "O13113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13113/entry#names_and_taxonomy" } ] }, { "name": "DAD-1", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" }, { "id": "O13113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13113/entry#names_and_taxonomy" } ] }, { "name": "Defender against cell death 1", "type": "synonym", "evidence": [ { "id": "O13113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13113/entry#names_and_taxonomy" } ] }, { "name": "Oligosaccharyl transferase subunit DAD1", "type": "synonym", "evidence": [ { "id": "O13113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13113/entry#names_and_taxonomy" } ] }, { "name": "apoptotic suppressor", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] }, { "name": "defender against cell death 1 protein", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] }, { "name": "defender against death protein 1", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] }, { "name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] }, { "name": "oligosaccharyl transferase subunit DAD1", "type": "synonym", "evidence": [ { "id": "NP_001007474", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: U83627.1, BU239625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U83833.1. On Nov 26, 2004 this sequence version replaced XP_418059.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ] }, { "annotation": "Data show that three isolated genes: Defender Against Cell Death (Dad1), Polyubiquitin II (UbII) and Ferritin Heavy chain (fth1), are implicated in Programmed Cell Death (PCD).", "evidence": [ { "database": "RefSeq", "id": "NP_001007474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" }, { "database": "PubMed", "id": "21305469", "url": "https://glygen.org/publication/PubMed/21305469" } ] }, { "annotation": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "O13113", "url": "https://www.uniprot.org/uniprotkb/O13113#function" }, { "database": "UniProtKB", "id": "E2R4X3", "url": "https://www.uniprot.org/uniprotkb/E2R4X3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O13113", "url": "https://www.uniprot.org/uniprotkb/O13113" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DAD1", "url": "https://www.uniprot.org/uniprotkb/O13113", "locus": { "chromosome": "27", "start_pos": 114902, "end_pos": 112040, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022066", "url": "https://www.ensembl.org/id/ENSGALG00010022066" } ] } } ], "crossref": [ { "id": "O13113", "url": "https://alphafold.ebi.ac.uk/entry/O13113", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035626", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395343", "url": "https://www.ncbi.nlm.nih.gov/gene/395343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395343", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIILHIV", "url": "https://omabrowser.org/oma/group/HIILHIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "O13113", "url": "https://www.orthodb.org/?gene=O13113", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10705:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10705:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O13113", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O13113", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9931295", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O13113", "url": "https://www.uniprot.org/uniprotkb/O13113", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O13113-1", "url": "https://www.uniprot.org/uniprotkb/O13113-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTAGSGVGAAGSVGSVVRRFLAEYGSGTSSRLKVLDAYLLYVMLTGALQFGYCLGVGTFPFNSFLSGFISAVGSFILGVCLRIQINPQNKGEFQGISPERAFADFLFANTILHLVVINFVG", "length": 123, "header": "sp|O13113-1|DAD1_CHICK Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 OS=Gallus gallus OX=9031 GN=DAD1 PE=2 SV=1 CANONICAL=O13113-1" }, "isoforms": [ { "isoform_ac": "O13113-1", "url": "https://www.uniprot.org/uniprotkb/O13113/entry#O13113-1", "sequence": { "sequence": "MSGTAGSGVGAAGSVGSVVRRFLAEYGSGTSSRLKVLDAYLLYVMLTGALQFGYCLGVGTFPFNSFLSGFISAVGSFILGVCLRIQINPQNKGEFQGISPERAFADFLFANTILHLVVINFVG", "length": 123, "header": "sp|O13113-1|DAD1_CHICK Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 OS=Gallus gallus OX=9031 GN=DAD1 PE=2 SV=1 CANONICAL=O13113-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Regulation of programmed cell death during neural induction in the chick embryo.", "journal": "The International journal of developmental biology", "date": "2011", "authors": "Gibson Anna, Robinson Neil, Streit Andrea, Sheng Guojun, Stern Claudio D", "evidence": [ { "database": "RefSeq", "id": "NP_001007474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007474" } ], "reference": [ { "type": "PubMed", "id": "21305469", "url": "https://glygen.org/publication/PubMed/21305469" } ] }, { "title": "A highly conserved apoptotic suppressor gene is located near the chicken T-cell receptor alpha chain constant region.", "journal": "Immunogenetics", "date": "1997", "authors": "Wang K, Gan L, Kuo C L, Hood L", "evidence": [ { "database": "UniProtKB", "id": "O13113", "url": "https://www.uniprot.org/uniprotkb/O13113" } ], "reference": [ { "type": "PubMed", "id": "9271627", "url": "https://glygen.org/publication/PubMed/9271627" } ] } ], "pathway": [ { "id": "gga:395343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395343", "resource": "KEGG Pathway" }, { "id": "R-GGA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" }, { "id": "R-GGA-9931295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931295", "resource": "Reactome", "description": "PD-L1(CD274) glycosylation and translocation to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HRC5-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "Dad1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "length": 113 }, "evidence": [ { "id": "O13113", "url": "https://omabrowser.org/oma/group/O13113/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "length": 113 }, "evidence": [ { "id": "O13113", "url": "https://omabrowser.org/oma/group/O13113/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61804-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "Dad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "length": 113 }, "evidence": [ { "id": "O13113", "url": "https://omabrowser.org/oma/group/O13113/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61805-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "Dad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "length": 113 }, "evidence": [ { "id": "O13113", "url": "https://omabrowser.org/oma/group/O13113/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q29036-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein 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] }, { "uniprot_canonical_ac": "O13268-1", "uniprot_ac": "O13268", "uniprot_id": "PSA7_CHICK", "mass": { "chemical_mass": 28072.0, "monoisotopic_mass": 28072.0 }, "refseq": { "ac": "NP_989944", "name": "proteasome subunit alpha type-7 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" }, "gene_names": [ { "name": "PSMA7", "type": "recommended", "evidence": [ { "id": "O13268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13268" } ] }, { "name": "PSMA7", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] } ], "protein_names": [ { "name": "Proteasome subunit alpha type-7", "type": "recommended", "evidence": [ { "id": "O13268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13268/entry#names_and_taxonomy" } ] }, { "name": "GPRO-28", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" }, { "id": "O13268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13268/entry#names_and_taxonomy" } ] }, { "name": "proteasome (prosome, macropain) subunit, alpha type, 7", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] }, { "name": "proteasome 28 kDa subunit homolog", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] }, { "name": "proteasome subunit alpha type-7 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] }, { "name": "proteasome subunit alpha type-7", "type": "synonym", "evidence": [ { "id": "NP_989944", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01026864.1, HAEK01051541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On Oct 17, 2021 this sequence version replaced NP_989944.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944" } ] }, { "annotation": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268#function" }, { "database": "UniProtKB", "id": "O14818", "url": "https://www.uniprot.org/uniprotkb/O14818#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMA7", "url": "https://www.uniprot.org/uniprotkb/O13268", "locus": { "chromosome": "20", "start_pos": 8076857, "end_pos": 8083817, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022808", "url": "https://www.ensembl.org/id/ENSGALG00010022808" } ] } } ], "crossref": [ { "id": "O13268", "url": "https://alphafold.ebi.ac.uk/entry/O13268", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03755", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03755", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395318", "url": "https://www.ncbi.nlm.nih.gov/gene/395318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "O13268", "url": "https://www.ebi.ac.uk/intact/interactors/id:O13268*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395318", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395318", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "O13268", "url": "https://www.orthodb.org/?gene=O13268", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10584", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10584", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O13268", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O13268", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_989944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O13268-1", "url": "https://www.uniprot.org/uniprotkb/O13268-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSKRRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVRVEFEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILTSPEEIEKYVAEIEKEKEENEKKKQKKTS", "length": 249, "header": "sp|O13268-1|PSA7_CHICK Isoform 1 of Proteasome subunit alpha type-7 OS=Gallus gallus OX=9031 GN=PSMA7 PE=2 SV=1 CANONICAL=O13268-1" }, "isoforms": [ { "isoform_ac": "O13268-1", "url": "https://www.uniprot.org/uniprotkb/O13268/entry#O13268-1", "sequence": { "sequence": "MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSKRRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVRVEFEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILTSPEEIEKYVAEIEKEKEENEKKKQKKTS", "length": 249, "header": "sp|O13268-1|PSA7_CHICK Isoform 1 of Proteasome subunit alpha type-7 OS=Gallus gallus OX=9031 GN=PSMA7 PE=2 SV=1 CANONICAL=O13268-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Differential expression of a proteasomal subunit during chick development.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1997", "authors": "Hutson M R, Rhodes M R, Kirby M L", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "reference": [ { "type": "PubMed", "id": "9168992", "url": "https://glygen.org/publication/PubMed/9168992" } ] } ], "pathway": [ { "id": "gga:395318", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395318", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "pmid": "" }, { "name": "proteasome core complex, alpha-subunit complex", "id": "GO:0019773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019773", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "pmid": "" }, { "name": "proteasome core complex", "id": "GO:0005839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005839", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "O13268", "url": "https://www.uniprot.org/uniprotkb/O13268" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-O13268-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 249, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-O13268-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/O13268" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "O42148-1", "uniprot_ac": "O42148", "uniprot_id": "OAZ1_CHICK", "mass": { "chemical_mass": 24315.0, "monoisotopic_mass": 24315.0 }, "refseq": { "ac": "NP_990247", "name": "ornithine decarboxylase antizyme 1", "summary": "The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as by inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization (PMID:16120325). [provided by RefSeq, Jul 2014].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" }, "gene_names": [ { "name": "OAZ", "type": "recommended", "evidence": [ { "id": "O42148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42148" } ] }, { "name": "OAZ1", "type": "synonym", "evidence": [ { "id": "NP_990247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" } ] }, { "name": "OAZ", "type": "synonym", "evidence": [ { "id": "NP_990247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" } ] } ], "protein_names": [ { "name": "Ornithine decarboxylase antizyme 1", "type": "recommended", "evidence": [ { "id": "O42148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42148/entry#names_and_taxonomy" } ] }, { "name": "ODC-Az", "type": "synonym", "evidence": [ { "id": "NP_990247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" }, { "id": "O42148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42148/entry#names_and_taxonomy" } ] }, { "name": "antizyme 1", "type": "synonym", "evidence": [ { "id": "NP_990247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" } ] }, { "name": "ornithine decarboxylase antizyme 1", "type": "synonym", "evidence": [ { "id": "NP_990247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF007806.1, CV861356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ribosomal slippage :: inferred from conservation ##RefSeq-Attributes-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF007806.1. On Jan 3, 2005 this sequence version replaced XP_418195.1. The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as by inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization (PMID:16120325). [provided by RefSeq, Jul 2014].", "evidence": [ { "database": "RefSeq", "id": "NP_990247", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247" } ] }, { "annotation": "Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148#function" }, { "database": "UniProtKB", "id": "P54368", "url": "https://www.uniprot.org/uniprotkb/P54368#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OAZ", "url": "https://www.uniprot.org/uniprotkb/O42148", "locus": {} } ], "crossref": [ { "id": "O42148", "url": "https://alphafold.ebi.ac.uk/entry/O42148", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000812", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000812", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395746", "url": "https://www.ncbi.nlm.nih.gov/gene/395746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395746", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395746", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVDHVFI", "url": "https://omabrowser.org/oma/group/HVDHVFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "O42148", "url": "https://www.orthodb.org/?gene=O42148", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10279:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10279:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:O42148", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:O42148", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990247", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990247", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O42148-1", "url": "https://www.uniprot.org/uniprotkb/O42148-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSSLQRILNSHCFAREKEGNKSTIMPAVLSLSTGQSSSRVPFNCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNVTEELTSNNRTRILNVQSRLTDAKHISWRAVLNNNNLYIEIPSGALPEGSKDSFAVLLEFAEEQLQVDHVFICFHKNRDDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERDSSEEE", "length": 216, "header": "sp|O42148-1|OAZ1_CHICK Isoform 1 of Ornithine decarboxylase antizyme 1 OS=Gallus gallus OX=9031 GN=OAZ PE=2 SV=3 CANONICAL=O42148-1" }, "isoforms": [ { "isoform_ac": "O42148-1", "url": "https://www.uniprot.org/uniprotkb/O42148/entry#O42148-1", "sequence": { "sequence": "MVKSSLQRILNSHCFAREKEGNKSTIMPAVLSLSTGQSSSRVPFNCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHNLSANLFYSDNRLNVTEELTSNNRTRILNVQSRLTDAKHISWRAVLNNNNLYIEIPSGALPEGSKDSFAVLLEFAEEQLQVDHVFICFHKNRDDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERDSSEEE", "length": 216, "header": "sp|O42148-1|OAZ1_CHICK Isoform 1 of Ornithine decarboxylase antizyme 1 OS=Gallus gallus OX=9031 GN=OAZ PE=2 SV=3 CANONICAL=O42148-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The chicken cDNA for ornithine decarboxylase antizyme.", "journal": "Biochim. Biophys. Acta", "date": "1998", "authors": "Drozdowski B, Gong T W, Lomax M I", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "reference": [ { "type": "PubMed", "id": "9524208", "url": "https://glygen.org/publication/PubMed/9524208" } ] } ], "pathway": [ { "id": "gga:395746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395746", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P54368-1", "protein_name": "Ornithine decarboxylase antizyme 1", "gene_name": "OAZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKSSLQRILNSHCFAREKEGDKPSATIHASRTMPLLSLHSRGGSSSESSRVSLHCCSNPGPGPRWCSDAPHPPLKIPGGRGNSQRDHNLSANLFYSDDRLNVTEELTSNDKTRILNVQSRLTDAKRINWRTVLSGGSLYIEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEEE", "length": 228 }, "evidence": [ { "id": "O42148", "url": "https://omabrowser.org/oma/group/O42148/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54369-1", "protein_name": "Ornithine decarboxylase antizyme 1", "gene_name": "Oaz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSESSRVALNCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQSTLTEAKQVTWRAVWSGGGLYIELPAGPLPEGSKDSFAALLEFAEEQLQADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED", "length": 227 }, "evidence": [ { "id": "O42148", "url": "https://omabrowser.org/oma/group/O42148/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54370-1", "protein_name": "Ornithine decarboxylase antizyme 1", "gene_name": "Oaz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSESSRVALHCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQCTLTEAKQVTWRAVWNGGGLYIELPAGPLPEGSKDSFAALLEFAEEQLRADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED", "length": 227 }, "evidence": [ { "id": "O42148", "url": "https://omabrowser.org/oma/group/O42148/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ornithine decarboxylase inhibitor activity", "id": "GO:0008073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008073", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "O42148", "url": "https://www.uniprot.org/uniprotkb/O42148" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"uniprot_canonical_ac": "O42273-1", "uniprot_ac": "O42273", "uniprot_id": "TENP_CHICK", "mass": { "chemical_mass": 47435.0, "monoisotopic_mass": 47435.0 }, "refseq": {}, "gene_names": [ { "name": "TENP", "type": "recommended", "evidence": [ { "id": "O42273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42273" } ] } ], "protein_names": [ { "name": "Protein TENP", "type": "recommended", "evidence": [ { "id": "O42273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42273/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the developmental transition from cell proliferation to cell differentiation during neurogenesis.", "evidence": [ { "database": "UniProtKB", "id": "O42273", "url": "https://www.uniprot.org/uniprotkb/O42273#function" }, { "database": "PubMed", "id": "9514522", "url": "https://glygen.org/publication/PubMed/9514522" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "O42273", "url": "https://www.uniprot.org/uniprotkb/O42273" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TENP", "url": "https://www.uniprot.org/uniprotkb/O42273", "locus": {} } ], "crossref": [ { "id": "O42273", "url": "https://alphafold.ebi.ac.uk/entry/O42273", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00025", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00025", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00026", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00026", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395882", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46019:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46019:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "O42273", "url": "https://www.uniprot.org/uniprotkb/O42273", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O42273-1", "url": "https://www.uniprot.org/uniprotkb/O42273-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGALLALLDPVQPTRAPDCGGILTPLGLSYLAEVSKPHAEVVLRQDLMPKEPQTCSLAPWSPAGTELPAVKVADLWLSVIPEAGLRLGIEVELRIAPLHTVPMPVRISIRADLHVDMGPDGNLQLLTSACRPTVQAQSTREAESKSSRSILDKVVDVDKLCLDVSKLLLFPNEQLMSLTALFPVTPNCQLQYLALAAPVFSKQGIALSLQTTFQVAGAVVPVPVSPVPFSMPELASTSTSHLILALSEHFYTSLYFTLERAGAFNMTIPSMLTTATLAQKITQVGSLYHEDLPITLSAALRSSPRVVLEEGRAALKLFLTVHIGAGSPDFQSFLSVSADVTRAGLQLSVSDTRMMISTAVIEDAELSLAASNVGLVRAALLEELFLAPVCQQVPAWMDDVLREGVHLPHMSHFTYTDVNVVVHKDYVLVPCKLKLRSTMA", "length": 440, "header": "sp|O42273-1|TENP_CHICK Isoform 1 of Protein TENP OS=Gallus gallus OX=9031 GN=TENP PE=1 SV=1 CANONICAL=O42273-1" }, "isoforms": [ { "isoform_ac": "O42273-1", "url": "https://www.uniprot.org/uniprotkb/O42273/entry#O42273-1", "sequence": { "sequence": "MGALLALLDPVQPTRAPDCGGILTPLGLSYLAEVSKPHAEVVLRQDLMPKEPQTCSLAPWSPAGTELPAVKVADLWLSVIPEAGLRLGIEVELRIAPLHTVPMPVRISIRADLHVDMGPDGNLQLLTSACRPTVQAQSTREAESKSSRSILDKVVDVDKLCLDVSKLLLFPNEQLMSLTALFPVTPNCQLQYLALAAPVFSKQGIALSLQTTFQVAGAVVPVPVSPVPFSMPELASTSTSHLILALSEHFYTSLYFTLERAGAFNMTIPSMLTTATLAQKITQVGSLYHEDLPITLSAALRSSPRVVLEEGRAALKLFLTVHIGAGSPDFQSFLSVSADVTRAGLQLSVSDTRMMISTAVIEDAELSLAASNVGLVRAALLEELFLAPVCQQVPAWMDDVLREGVHLPHMSHFTYTDVNVVVHKDYVLVPCKLKLRSTMA", "length": 440, "header": "sp|O42273-1|TENP_CHICK Isoform 1 of Protein TENP OS=Gallus gallus OX=9031 GN=TENP PE=1 SV=1 CANONICAL=O42273-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Differential abundance of egg white proteins in laying hens treated with corticosterone.", "journal": "J. Agric. Food Chem.", "date": "2014", "authors": "Kim Jimin, Choi Yang-Ho", "evidence": [ { "database": "UniProtKB", "id": "O42273", "url": "https://www.uniprot.org/uniprotkb/O42273" } ], "reference": [ { "type": "PubMed", "id": "25436390", "url": "https://glygen.org/publication/PubMed/25436390" } ] }, { "title": "Identification and characterization of tenp, a gene transiently expressed before overt cell differentiation during neurogenesis.", "journal": "Journal of neurobiology", "date": "1998-03", "authors": "Yan R T, Wang S Z", "evidence": [ { "database": "UniProtKB", "id": "O42273", "url": "https://www.uniprot.org/uniprotkb/O42273" } ], "reference": [ { "type": "PubMed", "id": "9514522", "url": "https://glygen.org/publication/PubMed/9514522" } ] } ], "pathway": [ { "id": "gga:395882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395882", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, 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exon combination :: ERR2286007.55849.1, ERR2365562.58465.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992527, SAMEA103992648 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000042.1. On or before Dec 14, 2021 this sequence version replaced XP_015137956.2, XP_426070.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026686" } ] }, { "annotation": "G protein-coupled receptor for corticotropin/ACTH, primarily expressed in adrenal cortex where it plays a key role in the regulation of adrenocortical function. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and activating the cAMP-dependent signaling pathway, the MAPK cascade as well as the PKA pathway, leading to steroidogenic factor 1/NR5A1-mediated transcriptional activation. Activation by ACTH facilitates the release of adrenal glucocorticoids, including cortisol and corticosterone. 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Acta", "date": "1985", "authors": "Wilton S D, Crocker L A, Rogers G E", "evidence": [ { "database": "UniProtKB", "id": "P04459", "url": "https://www.uniprot.org/uniprotkb/P04459" } ], "reference": [ { "type": "PubMed", "id": "2578818", "url": "https://glygen.org/publication/PubMed/2578818" } ] }, { "title": "A comparison of genomic coding sequences for feather and scale keratins: structural and evolutionary implications.", "journal": "EMBO J.", "date": "1984", "authors": "Gregg K, Wilton S D, Parry D A, Rogers G E", "evidence": [ { "database": "UniProtKB", "id": "P04459", "url": "https://www.uniprot.org/uniprotkb/P04459" } ], "reference": [ { "type": "PubMed", "id": "6200321", "url": "https://glygen.org/publication/PubMed/6200321" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": 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"domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] }, { "name": "MYL4", "type": "synonym", "evidence": [ { "id": "NP_990810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] } ], "protein_names": [ { "name": "Myosin light chain, embryonic", "type": "recommended", "evidence": [ { "id": "P09540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09540/entry#names_and_taxonomy" } ] }, { "name": "L23", "type": "synonym", "evidence": [ { "id": "P09540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09540/entry#names_and_taxonomy" } ] }, { "name": "atrial, embryonic", "type": "synonym", "evidence": [ { "id": "NP_990810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] }, { "name": "myosin light chain, embryonic", "type": "synonym", "evidence": [ { "id": "NP_990810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] }, { "name": "myosin, light polypeptide 4, alkali", "type": "synonym", "evidence": [ { "id": "NP_990810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: J02823.1, HAEL01012144.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000363.1 and J02823.1. On or before May 31, 2014 this sequence version replaced XP_003642828.1, NP_990810.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P09540", "url": "https://www.uniprot.org/uniprotkb/P09540" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P09540", "locus": {} } ], "crossref": [ { "id": "P09540", "url": "https://alphafold.ebi.ac.uk/entry/P09540", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396472", "url": "https://www.ncbi.nlm.nih.gov/gene/396472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMFQHIA", "url": "https://omabrowser.org/oma/group/PMFQHIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P09540", "url": "https://www.orthodb.org/?gene=P09540", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:P09540", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P09540", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P09540", "url": "https://www.uniprot.org/uniprotkb/P09540", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09540-1", "url": "https://www.uniprot.org/uniprotkb/P09540-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLKKPDPKKDAAKAAAAPEVPKEFTFDPKSVKIEFAAEQIEEFKEAFSLFDRTPTGAMQITYAQCGDVLRALGHNPTNAEVLKVLGKPKPEDLNTKMLDFETFLPILQHFTRNREQGTFEDFVEGLRVFDKEGNGLVMGAELRHVLVTLGEKMTESEVEQLMAGLEDANGCINYEAFVKHIMSG", "length": 185, "header": "sp|P09540-1|MLEX_CHICK Isoform 1 of Myosin light chain, embryonic OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P09540-1" }, "isoforms": [ { "isoform_ac": "P09540-1", "url": "https://www.uniprot.org/uniprotkb/P09540/entry#P09540-1", "sequence": { "sequence": "MPLKKPDPKKDAAKAAAAPEVPKEFTFDPKSVKIEFAAEQIEEFKEAFSLFDRTPTGAMQITYAQCGDVLRALGHNPTNAEVLKVLGKPKPEDLNTKMLDFETFLPILQHFTRNREQGTFEDFVEGLRVFDKEGNGLVMGAELRHVLVTLGEKMTESEVEQLMAGLEDANGCINYEAFVKHIMSG", "length": 185, "header": "sp|P09540-1|MLEX_CHICK Isoform 1 of Myosin light chain, embryonic OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P09540-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Isolation of the chick myosin alkali light chain gene expressed in embryonic gizzard muscle and transitional expression of the light chain gene family in vivo.", "journal": "J. Mol. Biol.", "date": "1988", "authors": "Nabeshima Y, Nabeshima Y, Kawashima M, Nakamura S, Nonomura Y, Fujii-Kuriyama Y", "evidence": [ { "database": "UniProtKB", "id": "P09540", "url": "https://www.uniprot.org/uniprotkb/P09540" } ], "reference": [ { "type": "PubMed", "id": "3225843", "url": "https://glygen.org/publication/PubMed/3225843" } ] }, { "title": "A common myosin light chain is expressed in chicken embryonic skeletal, cardiac, and smooth muscles and in brain continuously from embryo to adult.", "journal": "J. Biol. 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P10399-1", "uniprot_ac": "P10399", "uniprot_id": "POL1_CHICK", "mass": { "chemical_mass": 26354.0, "monoisotopic_mass": 26354.0 }, "refseq": {}, "gene_names": [ { "name": "POL", "type": "recommended", "evidence": [ { "id": "P10399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10399" } ] } ], "protein_names": [ { "name": "Retrovirus-related Pol polyprotein", "type": "recommended", "evidence": [ { "id": "P10399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10399/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P10399", "url": "https://www.uniprot.org/uniprotkb/P10399" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POL", "url": "https://www.uniprot.org/uniprotkb/P10399", "locus": {} } ], "crossref": [ { "id": "P10399", "url": "https://alphafold.ebi.ac.uk/entry/P10399", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "P10399", "url": "https://www.uniprot.org/uniprotkb/P10399", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P10399-1", "url": "https://www.uniprot.org/uniprotkb/P10399-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SAQPVRAFTPWVELLSLLLSKARTSAFRDFGKDLDIVHLPRFFRDSQILPDEILLALHGFGGKLRYAGSLPIFELARPLRVSLRLRVVASPLDGPTVFTDASSSTGQGAVVLTARTAPAAVLHVRSHSDVPGFFTTGNALADQHAGHKVLTVREADLHSTLHLGARALSRTCSIPMAVAREVVQACPHCNSAPALSAGVNPRGIAPLDVWQTDFTLEPRLAPRSWLAVTVDTASTVIVATQHGRAN", "length": 246, "header": "sp|P10399-1|POL1_CHICK Isoform 1 of Retrovirus-related Pol polyprotein OS=Gallus gallus OX=9031 GN=POL PE=4 SV=1 CANONICAL=P10399-1" }, "isoforms": [ { "isoform_ac": "P10399-1", "url": "https://www.uniprot.org/uniprotkb/P10399/entry#P10399-1", "sequence": { "sequence": "SAQPVRAFTPWVELLSLLLSKARTSAFRDFGKDLDIVHLPRFFRDSQILPDEILLALHGFGGKLRYAGSLPIFELARPLRVSLRLRVVASPLDGPTVFTDASSSTGQGAVVLTARTAPAAVLHVRSHSDVPGFFTTGNALADQHAGHKVLTVREADLHSTLHLGARALSRTCSIPMAVAREVVQACPHCNSAPALSAGVNPRGIAPLDVWQTDFTLEPRLAPRSWLAVTVDTASTVIVATQHGRAN", "length": 246, "header": "sp|P10399-1|POL1_CHICK Isoform 1 of Retrovirus-related Pol polyprotein OS=Gallus gallus OX=9031 GN=POL PE=4 SV=1 CANONICAL=P10399-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Presence of retrovirus reverse transcriptase-related gene sequences in avian cells lacking endogenous avian leukosis viruses.", "journal": "Proc. 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U.S.A.", "date": "1985", "authors": "Dunwiddie C, Faras A J", "evidence": [ { "database": "UniProtKB", "id": "P10399", "url": "https://www.uniprot.org/uniprotkb/P10399" } ], "reference": [ { "type": "PubMed", "id": "2410912", "url": "https://glygen.org/publication/PubMed/2410912" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "P10399", "url": "https://www.uniprot.org/uniprotkb/P10399" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P10399", "url": "https://www.uniprot.org/uniprotkb/P10399" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_990857" } ] }, { "name": "arylamine acetylase", "type": "synonym", "evidence": [ { "id": "NP_990857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990857" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: J03737.1, CD731555.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992415 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Mar 18, 2015 this sequence version replaced NP_990857.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990857" } ] }, { "annotation": "Cloning of the chick NAT promoter, the regulation of which is being characterized.", "evidence": [ { "database": "RefSeq", "id": "NP_990857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990857" }, { "database": "PubMed", "id": "17192617", "url": "https://glygen.org/publication/PubMed/17192617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P12275", "url": "https://www.uniprot.org/uniprotkb/P12275" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P12275", "locus": {} } ], "crossref": [ { "id": "P12275", "url": "https://alphafold.ebi.ac.uk/entry/P12275", "database": "AlphaFoldDB", "categories": [] }, { "id": "396537", "url": "https://www.ncbi.nlm.nih.gov/gene/396537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396537", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P12275", "url": "https://www.orthodb.org/?gene=P12275", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11786", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11786", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11786:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11786:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P12275", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P12275", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16613", "url": "https://www.rhea-db.org/rhea/16613", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "P12275", "url": "https://www.uniprot.org/uniprotkb/P12275", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P12275-1", "url": "https://www.uniprot.org/uniprotkb/P12275-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIQEYFSRISFDGSHKDADLQTLTAIFQHHIQAIPFENLSMHCGETIDLDLQATYNKIVKKKRGGWCMETNYLLFWALKEMGYDICVLGGNSYEPAKKAYTDEINHILLKVVIKGSSYIVDAGFGGGPYQTWLPMLLISGKDQPQIPGIFRFIEDNGIWYLEKVKRKHYVPEGSVPLTDNPEMGNIRKLYSFTLEPKHIDDFQELNAYLQVAPDTILQKKSICSLQTTDGFYALVGWTFSEMKYKYKEDADLLQTTTLTDEEVEKTLKDKFNIVLENKLIPVNVRG", "length": 287, "header": "sp|P12275-1|ARYL_CHICK Isoform 1 of Arylamine N-acetyltransferase, liver isozyme OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=P12275-1" }, "isoforms": [ { "isoform_ac": "P12275-1", "url": "https://www.uniprot.org/uniprotkb/P12275/entry#P12275-1", "sequence": { "sequence": "MNIQEYFSRISFDGSHKDADLQTLTAIFQHHIQAIPFENLSMHCGETIDLDLQATYNKIVKKKRGGWCMETNYLLFWALKEMGYDICVLGGNSYEPAKKAYTDEINHILLKVVIKGSSYIVDAGFGGGPYQTWLPMLLISGKDQPQIPGIFRFIEDNGIWYLEKVKRKHYVPEGSVPLTDNPEMGNIRKLYSFTLEPKHIDDFQELNAYLQVAPDTILQKKSICSLQTTDGFYALVGWTFSEMKYKYKEDADLLQTTTLTDEEVEKTLKDKFNIVLENKLIPVNVRG", "length": 287, "header": "sp|P12275-1|ARYL_CHICK Isoform 1 of Arylamine N-acetyltransferase, liver isozyme OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=P12275-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Chick acetylcholinesterase promoter regulation.", "journal": "Journal of molecular neuroscience : MN", "date": "2006", "authors": "Wan David C C, Zhang Xiang, Siow Nina L, Xie Heidi Q H, Tsim Karl W K", "evidence": [ { "database": "RefSeq", "id": "NP_990857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990857" } ], "reference": [ { "type": "PubMed", "id": "17192617", "url": "https://glygen.org/publication/PubMed/17192617" } ] }, { "title": "Arylamine N-acetyltransferase from chicken liver. I. Monoclonal antibodies, immunoaffinity purification, and amino acid sequences.", "journal": "J. Biol. Chem.", "date": "1988", "authors": "Deguchi T, Sakamoto Y, Sasaki Y, Uyemura K", "evidence": [ { "database": "UniProtKB", "id": "P12275", "url": "https://www.uniprot.org/uniprotkb/P12275" } ], "reference": [ { "type": "PubMed", "id": "2897359", "url": "https://glygen.org/publication/PubMed/2897359" } ] }, { "title": "Arylamine N-acetyltransferase from chicken liver II. Cloning of cDNA and expression in Chinese hamster ovary cells.", "journal": "J. Biol. Chem.", "date": "1988", "authors": "Ohsako S, Ohtomi M, Sakamoto Y, Uyemura K, Deguchi T", "evidence": [ { "database": "UniProtKB", "id": "P12275", "url": "https://www.uniprot.org/uniprotkb/P12275" } ], "reference": [ { "type": "PubMed", "id": "2897360", "url": "https://glygen.org/publication/PubMed/2897360" } ] } ], "pathway": [ { "id": "gga:396537", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396537", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "arylamine N-acetyltransferase activity", "id": "GO:0004060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004060", "evidence": [ { "database": "UniProtKB", "id": "P12275", "url": "https://www.uniprot.org/uniprotkb/P12275" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16613", "name": "", "equation": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P12275-1", "P13913-1", "P13914-1", "A0A8V0XNN0-1", "F1P5U3-1" ], "evidence": [ { "id": "16613", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16613" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XNN0", "gene_name": "NAT", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] } ] }, { "uniprot_ac": "F1P5U3", "gene_name": "PNAT10", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] } ] }, { "uniprot_ac": "P12275", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] } ] }, { "uniprot_ac": "P13913", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] } ] }, { "uniprot_ac": "P13914", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] }, { "ec_number": "2.3.1.118", "activity": "an N-hydroxyarylamine + acetyl-CoA = an N-acetoxyarylamine + CoA.", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-P12275-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 287, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P12275-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P12275" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.5", "ec_name": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "2.3.1.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.5" }, { "id": "2.3.1.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.5" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"P13544-1", "uniprot_ac": "P13544", "uniprot_id": "HXD1_CHICK", "mass": { "chemical_mass": 8411.0, "monoisotopic_mass": 8411.0 }, "refseq": {}, "gene_names": [ { "name": "HOXD1", "type": "recommended", "evidence": [ { "id": "P13544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13544" } ] }, { "name": "CHOX-1", "type": "synonym", "evidence": [ { "id": "P13544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13544" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-D1", "type": "recommended", "evidence": [ { "id": "P13544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13544/entry#names_and_taxonomy" } ] }, { "name": "Homeobox protein CHOX-1", "type": "synonym", "evidence": [ { "id": "P13544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13544/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "P13544", "url": "https://www.uniprot.org/uniprotkb/P13544#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P13544", "url": "https://www.uniprot.org/uniprotkb/P13544" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXD1", "url": "https://www.uniprot.org/uniprotkb/P13544", "locus": {} } ], "crossref": [ { "id": "P13544", "url": "https://alphafold.ebi.ac.uk/entry/P13544", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "P13544", "url": "https://www.orthodb.org/?gene=P13544", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45946", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45946", "database": "PANTHER", "categories": [ "Protein 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"AFSLRTSFSTRQLTELEKEFHFSRYLSRARRLEVARSLRLRDAQVKVWFQNRRMKQKKRERERWPDP", "length": 67, "header": "sp|P13544-1|HXD1_CHICK Isoform 1 of Homeobox protein Hox-D1 OS=Gallus gallus OX=9031 GN=HOXD1 PE=3 SV=1 CANONICAL=P13544-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The chicken homeo box genes CHox1 and CHox3: cloning, sequencing and expression during embryogenesis.", "journal": "Gene", "date": "1989", "authors": "Rangini Z, Frumkin A, Shani G, Guttmann M, Eyal-Giladi H, Gruenbaum Y, Fainsod A", "evidence": [ { "database": "UniProtKB", "id": "P13544", "url": "https://www.uniprot.org/uniprotkb/P13544" } ], "reference": [ { "type": "PubMed", "id": "2568317", "url": "https://glygen.org/publication/PubMed/2568317" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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], "crossref": [ { "id": "P13724", "url": "https://www.orthodb.org/?gene=P13724", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P13724", "url": "https://www.uniprot.org/uniprotkb/P13724", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13724-1", "url": "https://www.uniprot.org/uniprotkb/P13724-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QLHVNKARRPYIL", "length": 13, "header": "sp|P13724-1|NEUT_CHICK Isoform 1 of Neurotensin OS=Gallus gallus OX=9031 GN=NTS PE=1 SV=2 CANONICAL=P13724-1" }, "isoforms": [ { "isoform_ac": "P13724-1", "url": "https://www.uniprot.org/uniprotkb/P13724/entry#P13724-1", "sequence": { "sequence": "QLHVNKARRPYIL", "length": 13, "header": "sp|P13724-1|NEUT_CHICK Isoform 1 of Neurotensin OS=Gallus gallus OX=9031 GN=NTS PE=1 SV=2 CANONICAL=P13724-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The amino acid sequence of a smooth muscle-contracting peptide from chicken rectum. Identity to chicken neurotensin.", "journal": "Japanese journal of pharmacology", "date": "1987-08", "authors": "Iwabuchi H, Komori S, Ohashi H, Kimura S", "evidence": [ { "database": "UniProtKB", "id": "P13724", "url": "https://www.uniprot.org/uniprotkb/P13724" } ], "reference": [ { "type": "PubMed", "id": "3682409", "url": "https://glygen.org/publication/PubMed/3682409" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P13724", "url": "https://www.uniprot.org/uniprotkb/P13724" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood vessel diameter maintenance", "id": "GO:0097746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097746", "evidence": [ { "database": "UniProtKB", "id": "P13724", "url": 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"gene_names": [ { "name": "PNAT10", "type": "synonym", "evidence": [ { "id": "NP_990671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990671" } ] } ], "protein_names": [ { "name": "Arylamine N-acetyltransferase, pineal gland isozyme NAT-10", "type": "recommended", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.5", "type": "synonym", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913/entry#names_and_taxonomy" } ] }, { "name": "Arylamine acetylase", "type": "synonym", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913/entry#names_and_taxonomy" } ] }, { "name": "arylamine N-acetyltransferase, pineal gland isozyme NAT-10", "type": "synonym", "evidence": [ { "id": "NP_990671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990671" } ] }, { "name": "arylamine acetylase", "type": "synonym", "evidence": [ { "id": "NP_990671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990671" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01073107.1, X16021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000248.1. On Sep 23, 2021 this sequence version replaced NP_990671.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990671" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P13913", "url": "https://www.uniprot.org/uniprotkb/P13913" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P13913", "locus": {} } ], "crossref": [ { "id": "P13913", "url": "https://alphafold.ebi.ac.uk/entry/P13913", "database": "AlphaFoldDB", "categories": [] }, { "id": "396283", "url": "https://www.ncbi.nlm.nih.gov/gene/396283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396283", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P13913", "url": "https://www.orthodb.org/?gene=P13913", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11786", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11786", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11786:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11786:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P13913", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P13913", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-156582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16613", "url": "https://www.rhea-db.org/rhea/16613", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "P13913", "url": "https://www.uniprot.org/uniprotkb/P13913", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13913-1", "url": "https://www.uniprot.org/uniprotkb/P13913-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLEEYFARTGYKGSLENQDLETLTDIFQHHIRAVPFENLSIHCGEKITLELEHVYNKIVHKKRGGWCMENNQLLGWVLKCLGYDTSFLGAYVFNPHENAYATIMTHLLVKVVIEGKAYIVDAGFGVSYQMWQPMELVSGKDQPQAPGIFRFTEKNAIWYLEKMRRKQYIPNQNFSNSDLLEKKDCRKVYMFSLEPRTVEDFCFQCTYLQTSPDSLFTKKSICTLQTTDGFRALIGWTLTETKYNYKENMDLVEFITLKDEEVEKTLKDKFNITLERKLVPINVKGFYTI", "length": 290, "header": "sp|P13913-1|ARY1_CHICK Isoform 1 of Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P13913-1" }, "isoforms": [ { "isoform_ac": "P13913-1", "url": "https://www.uniprot.org/uniprotkb/P13913/entry#P13913-1", "sequence": { "sequence": "MNLEEYFARTGYKGSLENQDLETLTDIFQHHIRAVPFENLSIHCGEKITLELEHVYNKIVHKKRGGWCMENNQLLGWVLKCLGYDTSFLGAYVFNPHENAYATIMTHLLVKVVIEGKAYIVDAGFGVSYQMWQPMELVSGKDQPQAPGIFRFTEKNAIWYLEKMRRKQYIPNQNFSNSDLLEKKDCRKVYMFSLEPRTVEDFCFQCTYLQTSPDSLFTKKSICTLQTTDGFRALIGWTLTETKYNYKENMDLVEFITLKDEEVEKTLKDKFNITLERKLVPINVKGFYTI", "length": 290, "header": "sp|P13913-1|ARY1_CHICK Isoform 1 of Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P13913-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning.", "journal": "Eur. J. Biochem.", "date": "1989", "authors": "Ohtomi M, Sasaki M, Deguchi T", "evidence": [ { "database": "UniProtKB", "id": "P13913", "url": "https://www.uniprot.org/uniprotkb/P13913" } ], "reference": [ { "type": "PubMed", "id": "2583181", "url": "https://glygen.org/publication/PubMed/2583181" } ] } ], "pathway": [ { "id": "gga:396283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396283", "resource": "KEGG Pathway" }, { "id": "R-GGA-156582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156582", "resource": "Reactome", "description": "Acetylation" }, { "id": "R-GGA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "arylamine N-acetyltransferase activity", "id": "GO:0004060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004060", "evidence": [ { "database": "UniProtKB", "id": "P13913", "url": "https://www.uniprot.org/uniprotkb/P13913" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16613", "name": "", "equation": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P12275-1", "P13913-1", "P13914-1", "A0A8V0XNN0-1", "F1P5U3-1" ], "evidence": [ { "id": "16613", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16613" } ] }, { "id": "R-GGA-158832", "name": "The acetyl group from acetyl-CoA is transferred to NAT2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-158832", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-158832" } ] }, { "id": "R-GGA-174959", "name": "The acetyl group from acetyl-CoA is transferred to NAT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "P13913-1" ], "evidence": [ { "id": "R-GGA-174959", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174959" } ] }, { "id": "R-GGA-174963", "name": "NAT1 acetylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "P13913-1" ], "evidence": [ { "id": "R-GGA-174963", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174963" } ] }, { "id": "R-GGA-174967", "name": "NAT2 acetylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-174967", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174967" } ] }, { "id": "R-GGA-9753676", "name": "NAT1,2 acetylate APAP-Cys to APAP-Mer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9753653" ], "output_participant_list": [ "R-ALL-9753642" ], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-9753676", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753676" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9753642", "participant_name": "APAP-Mer [cytosol]", "crossref": [ { "id": "ZINC000002528460", "database": "ZINC", "url": "" }, { "id": "133438", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9753653", "participant_name": "APAP-Cys [cytosol]", "crossref": [ { "id": "133067", "database": "ChEBI", "url": "" }, { "id": "ZINC000002570863", "database": "ZINC", "url": "" }, { "id": "ZINC000021981126", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XNN0", "gene_name": "NAT", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] } ] }, { "uniprot_ac": "F1P5U3", "gene_name": "PNAT10", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] } ] }, { "uniprot_ac": "P12275", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] } ] }, { "uniprot_ac": "P13913", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] } ] }, { "uniprot_ac": "P13914", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] }, { "ec_number": "2.3.1.118", "activity": "an N-hydroxyarylamine + acetyl-CoA = an N-acetoxyarylamine + CoA.", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-P13913-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 290, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P13913-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P13913" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.5", "ec_name": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "2.3.1.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.5" }, { "id": "2.3.1.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.5" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P13914-1", "uniprot_ac": "P13914", "uniprot_id": "ARY2_CHICK", "mass": { "chemical_mass": 33664.0, "monoisotopic_mass": 33664.0 }, "refseq": { "ac": "NP_001004373", "name": "arylamine N-acetyltransferase, pineal gland isozyme NAT-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" }, "gene_names": [ { "name": "PNAT3", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "name": "p-NAT-3", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] } ], "protein_names": [ { "name": "Arylamine N-acetyltransferase, pineal gland isozyme NAT-3", "type": "recommended", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.118", "type": "synonym", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.5", "type": "synonym", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#names_and_taxonomy" } ] }, { "name": "Arylamine acetylase", "type": "synonym", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#names_and_taxonomy" } ] }, { "name": "N-acetyltransferase, pineal gland isozyme NAT-3", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "name": "N-hydroxyarylamine O-acetyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" }, { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#names_and_taxonomy" } ] }, { "name": "arylamide acetylase", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "name": "arylamine N-acetyltransferase 3", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "name": "arylamine N-acetyltransferase, pineal gland isozyme NAT-3", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "name": "arylamine acetylase", "type": "synonym", "evidence": [ { "id": "NP_001004373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X17480.1, HAEL01003095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000248.1. On Sep 17, 2004 this sequence version replaced XP_414170.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373" } ] }, { "annotation": "Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates, and participates in the detoxification of a plethora of hydrazine and arylamine drugs.", "evidence": [ { "database": "UniProtKB", "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914#function" }, { "database": "UniProtKB", "id": "P11245", "url": "https://www.uniprot.org/uniprotkb/P11245#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P13914", "locus": {} } ], "crossref": [ { "id": "P13914", "url": "https://alphafold.ebi.ac.uk/entry/P13914", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005473", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415809", "url": "https://www.ncbi.nlm.nih.gov/gene/415809", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415809", "url": 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001004373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16613", "url": "https://www.rhea-db.org/rhea/16613", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20277", "url": "https://www.rhea-db.org/rhea/20277", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13914-1", "url": "https://www.uniprot.org/uniprotkb/P13914-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIKEYFARISYGGSYEKPDLETLTEIFQHHIQAVPFENLSIHCGETIELDLAATYDKIVRKKRGGWCMENNHLLSWALKTLGYNVTLLGAKVYIPEHDAYADDIDHLLLKVVLHDKSYIVDGGFGMAYQLWQPMELISGKDQPQTPGIFRFVEENGTWYLEKVKRKQYVPNHSDSAPHNVDKEVCRRVYLFTLQPRDIEEFRARNLHLQTAPDSLFVTKSICSLQTPDGVRALVGWKLTEIKYNYKDNMDLVEIRILADEEMEKTLKEKFNITLDKKFVPINTSRLSLF", "length": 290, "header": "sp|P13914-1|ARY2_CHICK Isoform 1 of Arylamine N-acetyltransferase, pineal gland isozyme NAT-3 OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P13914-1" }, "isoforms": [ { "isoform_ac": "P13914-1", "url": "https://www.uniprot.org/uniprotkb/P13914/entry#P13914-1", "sequence": { "sequence": "MDIKEYFARISYGGSYEKPDLETLTEIFQHHIQAVPFENLSIHCGETIELDLAATYDKIVRKKRGGWCMENNHLLSWALKTLGYNVTLLGAKVYIPEHDAYADDIDHLLLKVVLHDKSYIVDGGFGMAYQLWQPMELISGKDQPQTPGIFRFVEENGTWYLEKVKRKQYVPNHSDSAPHNVDKEVCRRVYLFTLQPRDIEEFRARNLHLQTAPDSLFVTKSICSLQTPDGVRALVGWKLTEIKYNYKDNMDLVEIRILADEEMEKTLKEKFNITLDKKFVPINTSRLSLF", "length": 290, "header": "sp|P13914-1|ARY2_CHICK Isoform 1 of Arylamine N-acetyltransferase, pineal gland isozyme NAT-3 OS=Gallus gallus OX=9031 GN= PE=2 SV=1 CANONICAL=P13914-1" }, "locus": { "chromosome": "11", "start_pos": 15430557, "end_pos": 15429688, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017737.1", "url": "https://www.ensembl.org/id/ENSGALT00010017737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009807.1", "url": "https://www.ensembl.org/id/ENSGALP00010009807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning.", "journal": "Eur. J. Biochem.", "date": "1989", "authors": "Ohtomi M, Sasaki M, Deguchi T", "evidence": [ { "database": "UniProtKB", "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914" } ], "reference": [ { "type": "PubMed", "id": "2583181", "url": "https://glygen.org/publication/PubMed/2583181" } ] } ], "pathway": [ { "id": "gga:415809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415809", "resource": "KEGG Pathway" }, { "id": "R-GGA-156582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156582", "resource": "Reactome", "description": "Acetylation" }, { "id": "R-GGA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "arylamine N-acetyltransferase activity", "id": "GO:0004060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004060", "evidence": [ { "database": "UniProtKB", "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914" } ], "pmid": "" }, { "name": "N-hydroxyarylamine O-acetyltransferase activity", "id": "GO:0046990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046990", "evidence": [ { "database": "UniProtKB", "id": "P13914", "url": "https://www.uniprot.org/uniprotkb/P13914" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16613", "name": "", "equation": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P12275-1", "P13913-1", "P13914-1", "A0A8V0XNN0-1", "F1P5U3-1" ], "evidence": [ { "id": "16613", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16613" } ] }, { "id": "20277", "name": "", "equation": "an N-hydroxyarylamine + acetyl-CoA = an N-acetoxyarylamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P13914-1" ], "evidence": [ { "id": "20277", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20277" } ] }, { "id": "R-GGA-158832", "name": "The acetyl group from acetyl-CoA is transferred to NAT2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-158832", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-158832" } ] }, { "id": "R-GGA-174967", "name": "NAT2 acetylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-174967", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174967" } ] }, { "id": "R-GGA-9753676", "name": "NAT1,2 acetylate APAP-Cys to APAP-Mer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9753653" ], "output_participant_list": [ "R-ALL-9753642" ], "enzyme_list": [ "F1P5U3-1", "A0A8V0XNN0-1", "P13913-1", "P13914-1" ], "evidence": [ { "id": "R-GGA-9753676", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753676" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9753642", "participant_name": "APAP-Mer [cytosol]", "crossref": [ { "id": "ZINC000002528460", "database": "ZINC", "url": "" }, { "id": "133438", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9753653", "participant_name": "APAP-Cys [cytosol]", "crossref": [ { "id": "133067", "database": "ChEBI", "url": "" }, { "id": "ZINC000002570863", "database": "ZINC", "url": "" }, { "id": "ZINC000021981126", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XNN0", "gene_name": "NAT", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "A0A8V0XNN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNN0" } ] } ] }, { "uniprot_ac": "F1P5U3", "gene_name": "PNAT10", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "F1P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5U3" } ] } ] }, { "uniprot_ac": "P12275", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P12275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12275" } ] } ] }, { "uniprot_ac": "P13913", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] }, { "ec_number": "2.3.1.5", "activity": "", "evidence": [ { "id": "P13913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13913" } ] } ] }, { "uniprot_ac": "P13914", "gene_name": "", "activity": [ { "ec_number": "2.3.1.5", "activity": "an arylamine + acetyl-CoA = an N-acetylarylamine + CoA.", "evidence": [ { "id": "P13914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13914" } ] }, { "ec_number": "2.3.1.118", "activity": "an 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"id": "2.3.1.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.5" } ] }, { "ec_number": "2.3.1.118", "ec_name": "an N-hydroxyarylamine + acetyl-CoA = an N-acetoxyarylamine + CoA.", "evidence": [ { "id": "2.3.1.118", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.118" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P29203-1", "uniprot_ac": "P29203", "uniprot_id": "PYY_CHICK", "mass": { "chemical_mass": 4237.0, "monoisotopic_mass": 4237.0 }, "refseq": {}, "gene_names": [ { "name": "PYY", "type": "recommended", "evidence": [ { "id": "P29203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29203" } ] } ], "protein_names": [ { "name": "Peptide YY-like", "type": 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Also binds NPY5R. Receptor binding induces adenylate cyclase-inhibiting G protein-coupled receptor signaling, resulting in inhibition of cAMP production. Receptor activation by PYY also leads to an increase of intracellular Ca(2+) levels (By similarity). 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"https://www.uniprot.org/uniprotkb/P29203", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P29203-1", "url": "https://www.uniprot.org/uniprotkb/P29203-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AYPPKPESPGDAASPEEIAQYFSALRHYINLVTRQRY", "length": 37, "header": "sp|P29203-1|PYY_CHICK Isoform 1 of Peptide YY-like OS=Gallus gallus OX=9031 GN=PYY PE=1 SV=1 CANONICAL=P29203-1" }, "isoforms": [ { "isoform_ac": "P29203-1", "url": "https://www.uniprot.org/uniprotkb/P29203/entry#P29203-1", "sequence": { "sequence": "AYPPKPESPGDAASPEEIAQYFSALRHYINLVTRQRY", "length": 37, "header": "sp|P29203-1|PYY_CHICK Isoform 1 of Peptide YY-like OS=Gallus gallus OX=9031 GN=PYY PE=1 SV=1 CANONICAL=P29203-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The primary structure of a PYY-related peptide from chicken intestine suggests an anomalous site of cleavage of the signal peptide in preproPYY.", "journal": "FEBS letters", "date": "1992-11-30", "authors": "Conlon J M, O'Harte F", "evidence": [ { "database": "UniProtKB", "id": "P29203", "url": "https://www.uniprot.org/uniprotkb/P29203" } ], "reference": [ { "type": "PubMed", "id": "1446739", "url": "https://glygen.org/publication/PubMed/1446739" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P29203", "url": "https://www.uniprot.org/uniprotkb/P29203" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "P29203", "url": "https://www.uniprot.org/uniprotkb/P29203" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P29203-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 37, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P29203-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P29203" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"mass": { "chemical_mass": 56709.0, "monoisotopic_mass": 56709.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger protein CKR1", "type": "recommended", "evidence": [ { "id": "P30373", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30373/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P30373", "url": "https://www.uniprot.org/uniprotkb/P30373" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/P30373", "locus": {} } ], "crossref": [ { "id": "P30373", "url": "https://alphafold.ebi.ac.uk/entry/P30373", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P30373", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P30373", "database": "PRO", "categories": [ "Protein" ] }, { "id": "P30373", "url": "https://www.uniprot.org/uniprotkb/P30373", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P30373-1", "url": "https://www.uniprot.org/uniprotkb/P30373-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32046/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L37a", "type": "synonym", "evidence": [ { "id": "NP_001072961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072961" }, { "id": "P32046", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32046/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL43", "type": "synonym", "evidence": [ { "id": "NP_001072961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072961" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000233.1, CK607838.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Dec 9, 2006 this sequence version replaced XP_001233297.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001072961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072961" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046#function" }, { "database": "UniProtKB", "id": "P61513", "url": "https://www.uniprot.org/uniprotkb/P61513#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL37A", "url": "https://www.uniprot.org/uniprotkb/P32046", "locus": { "chromosome": "7", "start_pos": 22954381, "end_pos": 22957455, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019288", "url": "https://www.ensembl.org/id/ENSGALG00010019288" } ] } } ], "crossref": [ { "id": "P32046", "url": "https://alphafold.ebi.ac.uk/entry/P32046", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011475", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011475", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769981", "url": "https://www.ncbi.nlm.nih.gov/gene/769981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR002674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769981", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769981", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPRYGRK", "url": "https://omabrowser.org/oma/group/GPRYGRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P32046", "url": "https://www.orthodb.org/?gene=P32046", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48188:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48188:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P32046", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P32046", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001072961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001072961", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P32046-1", "url": "https://www.uniprot.org/uniprotkb/P32046-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRKAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 92, "header": "sp|P32046-1|RL37A_CHICK Isoform 1 of Large ribosomal subunit protein eL43 OS=Gallus gallus OX=9031 GN=RPL37A PE=1 SV=2 CANONICAL=P32046-1" }, "isoforms": [ { "isoform_ac": "P32046-1", "url": "https://www.uniprot.org/uniprotkb/P32046/entry#P32046-1", "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRKAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 92, "header": "sp|P32046-1|RL37A_CHICK Isoform 1 of Large ribosomal subunit protein eL43 OS=Gallus gallus OX=9031 GN=RPL37A PE=1 SV=2 CANONICAL=P32046-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The primary structure of chicken ribosomal protein L37a.", "journal": "Biochim. Biophys. Acta", "date": "1992", "authors": "Toku S, Tanaka T", "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046" } ], "reference": [ { "type": "PubMed", "id": "1380836", "url": "https://glygen.org/publication/PubMed/1380836" } ] }, { "title": "The structure of the gene encoding chicken ribosomal protein L37a.", "journal": "Eur. J. Biochem.", "date": "1993", "authors": "Machida M, Toku S, Kenmochi N, Tanaka T", "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046" } ], "reference": [ { "type": "PubMed", "id": "8477735", "url": "https://glygen.org/publication/PubMed/8477735" } ] } ], "pathway": [ { "id": "gga:769981", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769981", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UMQ6-1", "protein_name": "Large ribosomal subunit protein eL43", "gene_name": "RPL37A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H3Z5-1", "protein_name": "Large ribosomal subunit protein eL43", "gene_name": "Rpl37a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0CX25-1", "protein_name": "Large ribosomal subunit protein eL43A", "gene_name": "RPL43A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX26-1", "protein_name": "Large ribosomal subunit protein eL43B", "gene_name": "RPL43B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61513-1", "protein_name": "Large ribosomal subunit protein eL43", "gene_name": "RPL37A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61514-1", "protein_name": "Large ribosomal subunit protein eL43", "gene_name": "Rpl37a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { 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"MAKRTKKVGVVGKYGTRYGASLRKQVKKMEITQHGTYTCSFCGKDAVRRSSVGIWKCNGCRKVLAGGAWTMSTAAGATVRSTIRRLRELNN", "length": 91 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SRK6-1", "protein_name": "Large ribosomal subunit protein eL43z", "gene_name": "RPL37AB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTKRTKKARIVGKYGTRYGASLRKQIKKMEVSQHNKYFCEFCGKYSVKRKVVGIWGCKDCGKVKAGGAYTMNTASAVTVRSTIRRLREQTES", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VMU4-1", "protein_name": "Large ribosomal subunit protein eL43", "gene_name": "RpL37A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKRTKKVGIVGKYGTRYGASLRKMVKKMEITQHSKYTCSFCGKDSMKRAVVGIWSCKRCKRTVAGGAWVYSTTAAASVRSAVRRLRETKEQ", "length": 92 }, "evidence": [ { "id": "P32046", "url": "https://omabrowser.org/oma/group/P32046/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P32046", "url": "https://www.uniprot.org/uniprotkb/P32046" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11581:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11581:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P47836", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P47836", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P47836-1", "url": "https://www.uniprot.org/uniprotkb/P47836-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263, "header": "sp|P47836-1|RS4_CHICK Isoform 1 of Small ribosomal subunit protein eS4 OS=Gallus gallus OX=9031 GN=RPS4 PE=1 SV=2 CANONICAL=P47836-1" }, "isoforms": [ { "isoform_ac": "P47836-1", "url": "https://www.uniprot.org/uniprotkb/P47836/entry#P47836-1", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263, "header": "sp|P47836-1|RS4_CHICK Isoform 1 of Small ribosomal subunit protein eS4 OS=Gallus gallus OX=9031 GN=RPS4 PE=1 SV=2 CANONICAL=P47836-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Mass spectral data for 64 eluted peptides and structural modeling define peptide binding preferences for class I alleles in two chicken MHC-B haplotypes associated with opposite responses to Marek's disease.", "journal": "Immunogenetics", "date": "2008-09", "authors": "Sherman Mark A, Goto Ronald M, Moore Roger E, Hunt Henry D, Lee Terry D, Miller Marcia M", "evidence": [ { "database": "IEDB", "id": "423745", "url": "https://www.iedb.org/epitope/423745" } ], "reference": [ { "type": "PubMed", "id": "18612635", "url": "https://glygen.org/publication/PubMed/18612635" } ] }, { "title": "Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.", "journal": "Mol. Cell. Biol.", "date": "1994", "authors": "Zinn AR, Alagappan RK, Brown LG, Wool I, Page DC", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "reference": [ { "type": "PubMed", "id": "8139551", "url": "https://glygen.org/publication/PubMed/8139551" } ] } ], "pathway": [ { "id": "gga:396001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396001", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P0CX35-1", "protein_name": "Small ribosomal subunit protein eS4A", "gene_name": "RPS4A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL", "length": 261 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX36-1", "protein_name": "Small ribosomal subunit protein eS4B", "gene_name": "RPS4B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL", "length": 261 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P41042-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RpS4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIVMQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQLGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAKTH", "length": 261 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P47961-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RPS4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITSEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P62701-1", "protein_name": "Small ribosomal subunit protein eS4, X isoform", "gene_name": "RPS4X", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62702-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "Rps4x", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62703-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "Rps4x", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P79103-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RPS4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q642H9-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "rps4x", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPTGFMDVVSIEKTGENFRLIYDVKGRFTVHRITNEEAKYKLCKVRKILIGTKGIPHLVTHDARTIRYPDPLIKVNDTIRIDLDTGKITDFIKFETGNMCMVTGGANLGRIGVITNREKHPGSFDVVHVKDSIGNSFATRLSNIFVIGKGNKPWVSLPRGKGVRLTIAEERDKRLAAKQSSS", "length": 263 }, "evidence": [ { "id": "P47836", "url": "https://omabrowser.org/oma/group/P47836/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P47836", "url": "https://www.uniprot.org/uniprotkb/P47836" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P47836-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P47836-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P47836" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P48306-1", "uniprot_ac": "P48306", "uniprot_id": "NDUB4_CHICK", "mass": { "chemical_mass": 14938.0, "monoisotopic_mass": 14938.0 }, "refseq": {}, "gene_names": [ { "name": "NDUFB4", "type": "recommended", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "type": "recommended", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] }, { "name": "CI-B15", "type": "synonym", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] }, { "name": "Complex I-B15", "type": "synonym", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] }, { "name": "GGHPW", "type": "synonym", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] }, { "name": "NADH-ubiquinone oxidoreductase B15 subunit", "type": "synonym", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] }, { "name": "Protein Walter", "type": "synonym", "evidence": [ { "id": "P48306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306#function" }, { "database": "UniProtKB", "id": "O95168", "url": "https://www.uniprot.org/uniprotkb/O95168#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFB4", "url": "https://www.uniprot.org/uniprotkb/P48306", "locus": { "chromosome": "1", "start_pos": 79865890, "end_pos": 79876547, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024994", "url": "https://www.ensembl.org/id/ENSGALG00010024994" } ] } } ], "crossref": [ { 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"categories": [ "Protein" ] }, { "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P48306-1", "url": "https://www.uniprot.org/uniprotkb/P48306-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGPSRTAAEEYRPNRYVSLPAELDPATYDTPLEKRRAEAERLAIRARLKRQYLLQLNTPKPPRVIEDPALLRWDYARTHNVYPTFRPTPKTSFLGAVFAIGPILFWIAAFKTERVSSAGGVEHQGAPGCKT", "length": 133, "header": "sp|P48306-1|NDUB4_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Gallus gallus OX=9031 GN=NDUFB4 PE=3 SV=2 CANONICAL=P48306-1" }, "isoforms": [ { "isoform_ac": "P48306-1", "url": "https://www.uniprot.org/uniprotkb/P48306/entry#P48306-1", "sequence": { "sequence": "MASGPSRTAAEEYRPNRYVSLPAELDPATYDTPLEKRRAEAERLAIRARLKRQYLLQLNTPKPPRVIEDPALLRWDYARTHNVYPTFRPTPKTSFLGAVFAIGPILFWIAAFKTERVSSAGGVEHQGAPGCKT", "length": 133, "header": "sp|P48306-1|NDUB4_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Gallus gallus OX=9031 GN=NDUFB4 PE=3 SV=2 CANONICAL=P48306-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence of a novel chicken genomic DNA fragment that hybridizes to the murine Hox-3.1 homeobox.", "journal": "Gene", "date": "1992", "authors": "Goldberg G S, Kaczmarczyk W", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "reference": [ { "type": "PubMed", "id": "1359990", "url": "https://glygen.org/publication/PubMed/1359990" } ] }, { "title": "A chicken genomic DNA fragment that hybridizes to the murine Hox-3.1 homeobox is likely to encode the NADH ubiquinone oxidoreductase subunit B15.", "journal": "Gene", "date": "1993", "authors": "Goldberg G S, Kaczmarczyk W", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "reference": [ { "type": "PubMed", "id": "7901127", "url": "https://glygen.org/publication/PubMed/7901127" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "P48306", "url": "https://www.uniprot.org/uniprotkb/P48306" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P48306-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 133, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P48306-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P48306" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Essential for the proper assembly and activity of V-ATPase (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P49712", "url": "https://www.uniprot.org/uniprotkb/P49712#function" }, { "database": "UniProtKB", "id": "P15313", "url": "https://www.uniprot.org/uniprotkb/P15313#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P49712", "url": "https://www.uniprot.org/uniprotkb/P49712" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP6V1B", "url": "https://www.uniprot.org/uniprotkb/P49712", "locus": {} } ], "crossref": [ { "id": "P49712", "url": "https://alphafold.ebi.ac.uk/entry/P49712", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "P49712", "url": "https://www.uniprot.org/uniprotkb/P49712", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49712-1", "url": "https://www.uniprot.org/uniprotkb/P49712-1", "database": "UniProtKB", 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"https://www.uniprot.org/uniprotkb/P50594" } ] }, { "name": "MAGOH2", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "name": "MAGOHB", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "name": "MAGOH", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] } ], "protein_names": [ { "name": "Protein mago nashi homolog", "type": "recommended", "evidence": [ { "id": "P50594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50594/entry#names_and_taxonomy" } ] }, { "name": "mago homolog B, exon junction complex subunit", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "name": "mago-nashi homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "name": "mago-nashi homolog, proliferation-associated", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "name": "protein mago nashi homolog", "type": "synonym", "evidence": [ { "id": "NP_001383098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU285565.1, BU305613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU285565.1 and CO422787.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098" } ] }, { "annotation": "Required for pre-mRNA splicing as component of the spliceosome. Core component of the exon junction complex (EJC) and also involved in the nonsense-mediated decay (NMD) pathway. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).", "evidence": [ { "database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594#function" }, { "database": "UniProtKB", "id": "P61326", "url": "https://www.uniprot.org/uniprotkb/P61326#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAGOH", "url": "https://www.uniprot.org/uniprotkb/P50594", "locus": {} } ], "crossref": [ { "id": "P50594", "url": "https://alphafold.ebi.ac.uk/entry/P50594", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374226", "url": "https://www.ncbi.nlm.nih.gov/gene/374226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IRKEMWI", "url": "https://omabrowser.org/oma/group/IRKEMWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P50594", "url": "https://www.orthodb.org/?gene=P50594", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12638:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12638:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02792", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02792", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P50594", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P50594", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001383098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383098", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P50594-1", "url": "https://www.uniprot.org/uniprotkb/P50594-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 146, "header": "sp|P50594-1|MGN_CHICK Isoform 1 of Protein mago nashi homolog OS=Gallus gallus OX=9031 GN=MAGOH PE=2 SV=2 CANONICAL=P50594-1" }, "isoforms": [ { "isoform_ac": "P50594-1", "url": "https://www.uniprot.org/uniprotkb/P50594/entry#P50594-1", "sequence": { "sequence": "MASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 146, "header": "sp|P50594-1|MGN_CHICK Isoform 1 of Protein mago nashi homolog OS=Gallus gallus OX=9031 GN=MAGOH PE=2 SV=2 CANONICAL=P50594-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of avian glypican is developmentally regulated.", "journal": "Dev. 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"organism": "Sus scrofa", "sequence": { "sequence": "MSMASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 148 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GTN1-1", "protein_name": "Protein mago nashi homolog", "gene_name": "Magoh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 146 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P49028-1", "protein_name": "Protein mago nashi", "gene_name": "mago", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTEDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDTMIRKEAFVHQSVMEELKRIIIDSEIMQEDDLPWPPPDRVGRQELEIVIGDEHISFTTSKTGSLVDVNRSKDPEGLRCFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 147 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P61327-1", "protein_name": "Protein mago nashi homolog", "gene_name": "Magoh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 146 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0VC92-1", "protein_name": "Protein mago nashi homolog 2", "gene_name": "MAGOHB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAMASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "length": 148 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55E21-1", "protein_name": "Protein mago nashi homolog", "gene_name": "magoh", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDVDTKIELATDSAMDITSPENDNNKTTATATSSSETQTTEDILKTETQKQKDDFYLRYYVGHKGKYGHEFLEFEFRSGNKLRYANNSHYKSENLIRKEVCVSDGVISEIKKVILDSGIMLEDDKNWPEPDVVGKQELEIVFKDEHISFSTTKIGSLMDVEKSDDPEGLKVMFYLIQDLKCLVFSLIGLHFKIKPI", "length": 197 }, "evidence": [ { "id": "P50594", "url": "https://omabrowser.org/oma/group/P50594/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" 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"common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { 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"database": "UniProtKB", "id": "P50594", "url": "https://www.uniprot.org/uniprotkb/P50594" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P50594-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 146, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P50594-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P50594" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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The reference sequence was derived from JAENSK010000027.1. On May 30, 2014 this sequence version replaced XP_417201.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates and exon combination used for the transcript record were based on alignment to mRNA DQ178665.1 from zebra finch (Taeniopygia guttata, taxonomy ID 59729).", "evidence": [ { "database": "RefSeq", "id": "NP_001280032", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280032" } ] }, { "annotation": "High affinity receptor for melatonin. 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Commun.", "date": "1995", "authors": "Kirby M L, Cheng G, Stadt H, Hunter G", "evidence": [ { "database": "UniProtKB", "id": "P51417", "url": "https://www.uniprot.org/uniprotkb/P51417" } ], "reference": [ { "type": "PubMed", "id": "7626060", "url": "https://glygen.org/publication/PubMed/7626060" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P51417", "url": "https://www.uniprot.org/uniprotkb/P51417" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P51417", "url": "https://www.uniprot.org/uniprotkb/P51417" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P51417", "url": "https://www.uniprot.org/uniprotkb/P51417" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P51417", "url": "https://www.uniprot.org/uniprotkb/P51417" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P51417-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 165, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P51417-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P51417" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"https://www.uniprot.org/uniprotkb/P55166/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAX9", "url": "https://www.uniprot.org/uniprotkb/P55166", "locus": { "chromosome": "5", "start_pos": 36247964, "end_pos": 36182351, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004755", "url": "https://www.ensembl.org/id/ENSGALG00010004755" } ] } } ], "crossref": [ { "id": "P55166", "url": "https://alphafold.ebi.ac.uk/entry/P55166", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "P55166", "url": "https://www.orthodb.org/?gene=P55166", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636", "url": 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"PAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLSQQGHYESYKQHQPPPQPPLPYNHIYSYPSPIAAAGAKVPTPPGVPAIPGTMAMPRTWPSSHSVTDILGIRSITDQVSDTSSYPSPKVEEWSSLGRSSFPPAAQHAVNGLEKSSLEQEAKYSQAHNGLPAVGSFVSAPAMSPYATSAQVSPYMPYSAAPSSYMAGHGWQHTAGTPLSPHGCDLPASLAFKGVQTAREGSHSVTASAL", "length": 339, "header": "sp|P55166-1|PAX9_CHICK Isoform 1 of Paired box protein Pax-9 OS=Gallus gallus OX=9031 GN=PAX9 PE=2 SV=1 CANONICAL=P55166-1" }, "isoforms": [ { "isoform_ac": "P55166-1", "url": "https://www.uniprot.org/uniprotkb/P55166/entry#P55166-1", "sequence": { "sequence": "PAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLSQQGHYESYKQHQPPPQPPLPYNHIYSYPSPIAAAGAKVPTPPGVPAIPGTMAMPRTWPSSHSVTDILGIRSITDQVSDTSSYPSPKVEEWSSLGRSSFPPAAQHAVNGLEKSSLEQEAKYSQAHNGLPAVGSFVSAPAMSPYATSAQVSPYMPYSAAPSSYMAGHGWQHTAGTPLSPHGCDLPASLAFKGVQTAREGSHSVTASAL", "length": 339, "header": "sp|P55166-1|PAX9_CHICK Isoform 1 of Paired box protein Pax-9 OS=Gallus gallus OX=9031 GN=PAX9 PE=2 SV=1 CANONICAL=P55166-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Expression of avian Pax1 and Pax9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm.", "journal": "Dev. Biol.", "date": "1996", "authors": "M\u00fcller T S, Ebensperger C, Neub\u00fcser A, Koseki H, Balling R, Christ B, Wilting J", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "reference": [ { "type": "PubMed", "id": "8812138", "url": "https://glygen.org/publication/PubMed/8812138" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P55166", "url": "https://www.uniprot.org/uniprotkb/P55166" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P55166-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 339, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P55166-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P55166" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P55166", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55166" }, { "id": "PRU00381", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00381" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Paired", "eco_id": "ECO_0000255", "start_pos": 2, "end_pos": 128, "start_aa": "Ala", "end_aa": "Lys", 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"uniprot_canonical_ac": "P55168-1", "uniprot_ac": "P55168", "uniprot_id": "CCNC_CHICK", "mass": { "chemical_mass": 33259.0, "monoisotopic_mass": 33259.0 }, "refseq": { "ac": "NP_001161237", "name": "cyclin-C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237" }, "gene_names": [ { "name": "CCNC", "type": "recommended", "evidence": [ { "id": "P55168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55168" } ] }, { "name": "CCNC", "type": "synonym", "evidence": [ { "id": "NP_001161237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237" } ] }, { "name": "cyclin-C", "type": "synonym", "evidence": [ { "id": "NP_001161237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237" } ] } ], "protein_names": [ { "name": "Cyclin-C", "type": "recommended", "evidence": [ { "id": "P55168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P55168/entry#names_and_taxonomy" } ] }, { "name": "cyclin-C", "type": "synonym", "evidence": [ { "id": "NP_001161237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01009206.1, SRR13267655.98053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. On Nov 18, 2009 this sequence version replaced XP_419818.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001161237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNC", "url": "https://www.uniprot.org/uniprotkb/P55168", "locus": { "chromosome": "3", "start_pos": 71111046, "end_pos": 71093204, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004238", "url": "https://www.ensembl.org/id/ENSGALG00010004238" } ] } } ], "crossref": [ { "id": "P55168", "url": "https://alphafold.ebi.ac.uk/entry/P55168", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015471", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015471", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20514", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20514", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421791", "url": "https://www.ncbi.nlm.nih.gov/gene/421791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421791", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P55168", "url": "https://www.orthodb.org/?gene=P55168", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P55168", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P55168", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001161237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P55168-1", "url": "https://www.uniprot.org/uniprotkb/P55168-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "length": 283, "header": "sp|P55168-1|CCNC_CHICK Isoform 1 of Cyclin-C OS=Gallus gallus OX=9031 GN=CCNC PE=3 SV=1 CANONICAL=P55168-1" }, "isoforms": [ { "isoform_ac": "P55168-1", "url": "https://www.uniprot.org/uniprotkb/P55168/entry#P55168-1", "sequence": { "sequence": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLISAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "length": 283, "header": "sp|P55168-1|CCNC_CHICK Isoform 1 of Cyclin-C OS=Gallus gallus OX=9031 GN=CCNC PE=3 SV=1 CANONICAL=P55168-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Alternatively spliced cyclin C mRNA is widely expressed, cell cycle regulated, and encodes a truncated cyclin box.", "journal": "Oncogene", "date": "1996", "authors": "Li H, Lahti J M, Kidd V J", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "reference": [ { "type": "PubMed", "id": "8761291", "url": "https://glygen.org/publication/PubMed/8761291" } ] } ], "pathway": [ { "id": "gga:421791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421791", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "P55168", "url": "https://www.uniprot.org/uniprotkb/P55168" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P55168-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 283, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P55168-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P55168" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "P61355-1", "uniprot_ac": "P61355", "uniprot_id": "RL27_CHICK", "mass": { "chemical_mass": 15798.0, "monoisotopic_mass": 15798.0 }, "refseq": { "ac": "NP_990668", "name": "large ribosomal subunit protein eL27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668" }, "gene_names": [ { "name": "RPL27", "type": "recommended", "evidence": [ { "id": "P61355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61355" } ] }, { "name": "RPL27", "type": "synonym", "evidence": [ { "id": "NP_990668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL27", "type": "recommended", "evidence": [ { "id": "P61355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61355/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L27", "type": "synonym", "evidence": [ { "id": "NP_990668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668" }, { "id": "P61355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61355/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL27", "type": "synonym", "evidence": [ { "id": "NP_990668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X56852.1, CN219365.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X56852.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668" } ] }, { "annotation": "Component of the large ribosomal subunit.", "evidence": [ { "database": "UniProtKB", "id": "P61355", "url": "https://www.uniprot.org/uniprotkb/P61355#function" }, { "database": "UniProtKB", "id": "P61353", "url": "https://www.uniprot.org/uniprotkb/P61353#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P61355", "url": "https://www.uniprot.org/uniprotkb/P61355" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL27", "url": "https://www.uniprot.org/uniprotkb/P61355", "locus": { "chromosome": "27", "start_pos": 5099982, "end_pos": 5097694, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022427", "url": "https://www.ensembl.org/id/ENSGALG00010022427" } ] } } ], "crossref": [ { "id": "P61355", "url": "https://alphafold.ebi.ac.uk/entry/P61355", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002837", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002837", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396280", "url": "https://www.ncbi.nlm.nih.gov/gene/396280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396280", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P61355", "url": "https://www.orthodb.org/?gene=P61355", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10497", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10497", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P61355", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P61355", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_990668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P61355", "url": "https://www.uniprot.org/uniprotkb/P61355", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P61355-1", "url": "https://www.uniprot.org/uniprotkb/P61355-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "length": 136, "header": "sp|P61355-1|RL27_CHICK Isoform 1 of Large ribosomal subunit protein eL27 OS=Gallus gallus OX=9031 GN=RPL27 PE=1 SV=2 CANONICAL=P61355-1" }, "isoforms": [ { "isoform_ac": "P61355-1", "url": "https://www.uniprot.org/uniprotkb/P61355/entry#P61355-1", "sequence": { "sequence": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "length": 136, "header": "sp|P61355-1|RL27_CHICK Isoform 1 of Large ribosomal subunit protein eL27 OS=Gallus gallus OX=9031 GN=RPL27 PE=1 SV=2 CANONICAL=P61355-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Ribosomal protein L27 is identical in chick and rat.", "journal": "Nucleic Acids Res.", "date": "1991", "authors": "Lebeau M C, Alvarez-Bolado G, Braissant O, Wahli W, Catsicas S", "evidence": [ { "database": "UniProtKB", "id": "P61355", "url": "https://www.uniprot.org/uniprotkb/P61355" } ], "reference": [ { "type": "PubMed", "id": "1709488", "url": "https://glygen.org/publication/PubMed/1709488" } ] } ], 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"https://data.glygen.org/ln2downloads/pdb/current/AF-P61355-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P61355" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"##Evidence-Data-START## Transcript exon combination :: HAEL01006503.1, AJ392850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On or before Dec 14, 2021 this sequence version replaced XP_015138440.1, XP_423181.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007968" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "P67883", "url": "https://www.uniprot.org/uniprotkb/P67883#function" }, { "database": "UniProtKB", "id": "P62888", "url": "https://www.uniprot.org/uniprotkb/P62888#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "P67883", "url": "https://www.uniprot.org/uniprotkb/P67883" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL30", "url": "https://www.uniprot.org/uniprotkb/P67883", "locus": { "chromosome": "2", "start_pos": 127052920, "end_pos": 127059476, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011650", "url": "https://www.ensembl.org/id/ENSGALG00010011650" } ] } } ], "crossref": [ { "id": "P67883", "url": "https://alphafold.ebi.ac.uk/entry/P67883", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029897", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029897", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425416", "url": "https://www.ncbi.nlm.nih.gov/gene/425416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "6KVM", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6KVM&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8JR4", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8JR4&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D 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"Enzyme and Pathway" ] }, { "id": "YFQGGNN", "url": "https://omabrowser.org/oma/group/YFQGGNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P67883", "url": "https://www.orthodb.org/?gene=P67883", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006kvm", "url": "https://www.rcsb.org/structure/pdb_00006kvm", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008jr4", "url": "https://www.rcsb.org/structure/pdb_00008jr4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6KVM", "url": "https://www.rcsb.org/structure/6KVM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8JR4", "url": "https://www.rcsb.org/structure/8JR4", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P67883", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P67883", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P67883", "url": "https://www.uniprot.org/uniprotkb/P67883", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P67883-1", "url": "https://www.uniprot.org/uniprotkb/P67883-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTSEK", "length": 115, "header": "sp|P67883-1|RL30_CHICK Isoform 1 of Large ribosomal subunit protein eL30 OS=Gallus gallus OX=9031 GN=RPL30 PE=1 SV=2 CANONICAL=P67883-1" }, "isoforms": [ { "isoform_ac": "P67883-1", "url": "https://www.uniprot.org/uniprotkb/P67883/entry#P67883-1", "sequence": { "sequence": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTSEK", "length": 115, "header": "sp|P67883-1|RL30_CHICK Isoform 1 of Large ribosomal subunit protein eL30 OS=Gallus gallus OX=9031 GN=RPL30 PE=1 SV=2 CANONICAL=P67883-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of peptides associated with chicken major histocompatibility complex class II molecules of B21 and B19 haplotypes.", "journal": "Immunogenetics", "date": "2005-02", "authors": "Haeri Mehran, Read Leah R, Wilkie Bruce N, Sharif Shayan", "evidence": [ { "database": "IEDB", "id": "194865", "url": "https://www.iedb.org/epitope/194865" } ], "reference": [ { "type": "PubMed", "id": "15650875", "url": "https://glygen.org/publication/PubMed/15650875" } ] }, { "title": "Chicken major histocompatibility complex class II molecules of the B haplotype present self and foreign peptides.", "journal": "Animal genetics", "date": "2006-08", "authors": "Cumberbatch J A, Brewer D, Vidavsky I, Sharif S", "evidence": [ { "database": "IEDB", "id": "194865", "url": "https://www.iedb.org/epitope/194865" } ], "reference": [ { "type": "PubMed", "id": "16879355", "url": "https://glygen.org/publication/PubMed/16879355" } ] }, { "title": "The structure of the gene encoding chicken ribosomal protein L30.", "journal": "Biochim. 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF23271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040538543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQRSSSPEKNEGSQSANPIGAGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1549, "header": "tr|A0A8V0Z5A1-1|A0A8V0Z5A1_CHICK Isoform 1 of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5A1-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQRSSSPEKNEGSQSANPIGAGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1549, "header": "tr|A0A8V0Z5A1-1|A0A8V0Z5A1_CHICK Isoform 1 of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044217.1", "url": "https://www.ensembl.org/id/ENSGALT00010044217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026300.1", "url": "https://www.ensembl.org/id/ENSGALP00010026300.1" } ] } }, { "isoform_ac": "A0A8V0Z5B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5B0-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1532, "header": "tr|A0A8V0Z5B0-1|A0A8V0Z5B0_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044235.1", "url": "https://www.ensembl.org/id/ENSGALT00010044235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026312.1", "url": "https://www.ensembl.org/id/ENSGALP00010026312.1" } ] } }, { "isoform_ac": "A0A8V0Z5T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5T4-1", "sequence": { "sequence": "MMAIGDDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQRSSSPEKNEGSQSANPIGAGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1317, "header": "tr|A0A8V0Z5T4-1|A0A8V0Z5T4_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44687144, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044206.1", "url": "https://www.ensembl.org/id/ENSGALT00010044206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026292.1", "url": "https://www.ensembl.org/id/ENSGALP00010026292.1" } ] } }, { "isoform_ac": "A0A8V0Z5U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5U4-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKTVKPALQDQLRSFWSSKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1540, "header": "tr|A0A8V0Z5U4-1|A0A8V0Z5U4_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044221.1", "url": "https://www.ensembl.org/id/ENSGALT00010044221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026303.1", "url": "https://www.ensembl.org/id/ENSGALP00010026303.1" } ] } }, { "isoform_ac": "A0A8V0Z5U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5U9-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKTVKPALQDQLRSFWSSKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1534, "header": "tr|A0A8V0Z5U9-1|A0A8V0Z5U9_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044228.1", "url": "https://www.ensembl.org/id/ENSGALT00010044228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026308.1", "url": "https://www.ensembl.org/id/ENSGALP00010026308.1" } ] } }, { "isoform_ac": "A0A8V0Z5V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z5V8-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKTVKPALQDQLRSFWSSKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1478, "header": "tr|A0A8V0Z5V8-1|A0A8V0Z5V8_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044253.1", "url": "https://www.ensembl.org/id/ENSGALT00010044253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026320.1", "url": "https://www.ensembl.org/id/ENSGALP00010026320.1" } ] } }, { "isoform_ac": "A0A8V0Z6T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z6T0-1", "sequence": { "sequence": "MRRLICKRICDYKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQRSSSPEKNEGSQSANPIGAGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1322, "header": "tr|A0A8V0Z6T0-1|A0A8V0Z6T0_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44676030, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044196.1", "url": "https://www.ensembl.org/id/ENSGALT00010044196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026286.1", "url": "https://www.ensembl.org/id/ENSGALP00010026286.1" } ] } }, { "isoform_ac": "A0A8V0Z6V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0Z6V8-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKTVKPALQDQLRSFWSSKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1514, "header": "tr|A0A8V0Z6V8-1|A0A8V0Z6V8_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044249.1", "url": "https://www.ensembl.org/id/ENSGALT00010044249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026319.1", "url": "https://www.ensembl.org/id/ENSGALP00010026319.1" } ] } }, { "isoform_ac": "A0A8V0ZCP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0ZCP2-1", "sequence": { "sequence": "MRRLICKRICDYKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLEDTSDKMDGTASEDGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQRSQSANPIGAGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALLLGDIRTKKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1313, "header": "tr|A0A8V0ZCP2-1|A0A8V0ZCP2_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44676030, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044200.1", "url": "https://www.ensembl.org/id/ENSGALT00010044200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026289.1", "url": "https://www.ensembl.org/id/ENSGALP00010026289.1" } ] } }, { "isoform_ac": "A0A8V0ZCR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A1/entry#A0A8V0ZCR9-1", "sequence": { "sequence": "MEPPGMDYFCAQVQQKDVGRRLQVGQELLEYLGDPARSPDVEQDQQRLDKVIDELAAWVNSSNFKVALLGLDVLGAFVYRLSGRFKSYIGTVLLPLIDRMGDAKDQVREQAQNLILKLMDEAAPPMYIWERLAVGFKHKNYRSREGVCLCLIATLNIYGAQPLSLSKLVPHLCAAFGDSNSQVRDAAILAIVEVYRHVGEKVRLDLTKRGIPPARLQTIFTKFDEVRDSGNMILSNISDKSFDDEESVDGNRPSSAASAFKIPAPKKPGNPSNSARKPGSAGGPKVGGSSKEGGAGAVDEDDFIKAFTDVPTVQIYSSRELEETLNKIREILSDDKHDWDQRTNALKKVRSLLVAGAAQYDGFFQHLRLLDGAFKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVAVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKAYLGLRNHFPSEAETLYNSLEPPYQRSLQTYLKNSGSIASLPQSDRSSSSSQESLNRPLSSKWSAASPASFAGRVSGSSKSVPSPGTLQRSRSDIDVNAAAGAKARHASGQTAGGGRLSAAGLPPGSYASLGRIRTKLSTPSLGIGNSKTDSRGRSRTKVVSQSQPGSRSGSPGRVLTTTTLSTMNTGVQRVLVNPAAAQKRSKIPRSQGCSREASPSRLSVARGSRIPRPSVSQGCSREASRESSRDTSPVRSFPPLASRHHSRSTGALYAPDAYGATGTSFGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPVRRRYESYGMYSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKRLCEIFTRMFADPHSKVFSMFLETLVDFIQVHKEDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFSILMRFTVDQTQTPSLKTVKPALQDQLRSFWSSKVKVAILKYIETLAQQMDPGDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLRNTGNSGQGSMGSPLTRPTPCSPASWSSPLTSPTNTSQNTLSPSAFDYDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMNEPVKRDSKRDDVDSIGSASGIADLRAGSGISDTGRTALDNKTSLLNTMPPHSSPRSRDYNPYNYSDSSFNKSALKEAMFDDDAEQFPDEPPMDHSDLVAELLKELSNHNERVEERKAALYELMKLTQEESFGVWDEHFKTILLLLLETLGDKEHAIRALAFKVLREILRNQPARFKNYAELTIMKTLEAHKDPHKEVVRSAEEAASMLAISISPDQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLTQLLPEIVPGLIQGYDNSESSVRKACVFCLVAIHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGPGDTTADLSGQS", "length": 1526, "header": "tr|A0A8V0ZCR9-1|A0A8V0ZCR9_CHICK Computationally mapped isoform of Cytoplasmic linker associated protein 2 OS=Gallus gallus OX=9031 GN=CLASP2 PE=1 SV=1 CANONICAL=A0A8V0Z5A1-1" }, "locus": { "chromosome": "2", "start_pos": 44720660, "end_pos": 44587349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044243.1", "url": "https://www.ensembl.org/id/ENSGALT00010044243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026316.1", "url": "https://www.ensembl.org/id/ENSGALP00010026316.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": 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"ac": "XP_025005272", "name": "dachshund homolog 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005272" }, "gene_names": [ { "name": "DACH2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ] }, { "name": "DACH2", "type": "synonym", "evidence": [ { "id": "XP_025005272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005272" } ] } ], "protein_names": [ { "name": "Dachshund family transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2/entry#names_and_taxonomy" } ] }, { "name": "dachshund homolog 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025005272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005272" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005272.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005272" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DACH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2", "locus": { "chromosome": "4", "start_pos": 8231767, "end_pos": 8499040, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018165", "url": "https://www.ensembl.org/id/ENSGALG00010018165" } ] } } ], "crossref": [ { "id": "A0A8V0Z5B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21081", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21081", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395576", "url": "https://www.ncbi.nlm.nih.gov/gene/395576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395576", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5B2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6C8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC73", "url": "https://www.orthodb.org/?gene=A0A8V0ZC73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC98", "url": "https://www.orthodb.org/?gene=A0A8V0ZC98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12577:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12577:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSAPPVIAATSSGGGAGGSAGLFRADPLYSSPAESPRLTNSLVNSFLSAGGGGTGAGSGGGGGNECKMVDLHGVKVASFLVEGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNASSRPGRPPKRSLGVAIQENARLLPHGVPGLLSPGLISPTDLRTLFFPDETQIRIAKLKTLQIQGLTAAAMAEAMKLQKMKLMAMNSLHGSGSQNGTESENEELNSNAGGSESSWDKDKLQSPITTGSQHSIGHPTLSGQSSLGSAHPLSPLQQNHLLTNRIDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSPLSRAGASVIKERIQDSPSPAPSLEDSQRPGSHASSHQSSSVSSSPSQLDNTPDRIAMLTNSREGELIDQETGTSLKKMQKEKEEVQIAIPIMKPTLDKVQLAGQALPPGFPAPFLFADGLSSVETLLTNIQGLLKVAVDNARVQEKQIQQEKKELKMELCRERELRESLERQLTAELQSRATIQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATSGDGLRMLNDAGIPDMEIEHNGTQHDSAAMQENRTYIKPTIMY", "length": 631, "header": "tr|A0A8V0Z5B2-1|A0A8V0Z5B2_CHICK Isoform 1 of Dachshund family transcription factor 2 OS=Gallus gallus OX=9031 GN=DACH2 PE=3 SV=1 CANONICAL=A0A8V0Z5B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2/entry#A0A8V0Z5B2-1", "sequence": { "sequence": "MAVSAPPVIAATSSGGGAGGSAGLFRADPLYSSPAESPRLTNSLVNSFLSAGGGGTGAGSGGGGGNECKMVDLHGVKVASFLVEGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNASSRPGRPPKRSLGVAIQENARLLPHGVPGLLSPGLISPTDLRTLFFPDETQIRIAKLKTLQIQGLTAAAMAEAMKLQKMKLMAMNSLHGSGSQNGTESENEELNSNAGGSESSWDKDKLQSPITTGSQHSIGHPTLSGQSSLGSAHPLSPLQQNHLLTNRIDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSPLSRAGASVIKERIQDSPSPAPSLEDSQRPGSHASSHQSSSVSSSPSQLDNTPDRIAMLTNSREGELIDQETGTSLKKMQKEKEEVQIAIPIMKPTLDKVQLAGQALPPGFPAPFLFADGLSSVETLLTNIQGLLKVAVDNARVQEKQIQQEKKELKMELCRERELRESLERQLTAELQSRATIQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATSGDGLRMLNDAGIPDMEIEHNGTQHDSAAMQENRTYIKPTIMY", "length": 631, "header": "tr|A0A8V0Z5B2-1|A0A8V0Z5B2_CHICK Isoform 1 of Dachshund family transcription factor 2 OS=Gallus gallus OX=9031 GN=DACH2 PE=3 SV=1 CANONICAL=A0A8V0Z5B2-1" }, "locus": { "chromosome": "4", "start_pos": 8498939, "end_pos": 8234834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043904.1", "url": "https://www.ensembl.org/id/ENSGALT00010043904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026113.1", "url": "https://www.ensembl.org/id/ENSGALP00010026113.1" } ] } }, { "isoform_ac": "A0A8V0Z6C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2/entry#A0A8V0Z6C8-1", "sequence": { "sequence": "MAVSAPPVIAATSSGGGAGGSAGLFRADPLYSSPAESPRLTNSLVNSFLSAGGGGTGAGSGGGGGNECKMVDLHGVKVASFLVEGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNASSRPGRPPKRSLGVAIQENARLLPHGVPGLLSPGLISPTGLTAAAMAEAMKLQKMKLMAMNSLHGSGSQNGTESENEELNSNAGIDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSPLSRAGASVIKERIQDSPSPAPSLEDSQRPGSHASSHQSSSVSSSPSQLDNTPDRIAMLTNSREGELIDQETGTSLKKMQKEKEEVQIAIPIMKPTLDKVQLAGQALPPGFPAPFLFADGLSSVETLLTNIQGLLKVAVDNARVQEKQIQQEKKELKMELCRERELRESLERQLTAELQSRATIQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATSGDGLRMLNDAGIPDMEIEHNGTQHDSAAMQENRTYIKPTIMY", "length": 555, "header": "tr|A0A8V0Z6C8-1|A0A8V0Z6C8_CHICK Computationally mapped isoform of Dachshund family transcription factor 2 OS=Gallus gallus OX=9031 GN=DACH2 PE=3 SV=1 CANONICAL=A0A8V0Z5B2-1" }, "locus": { "chromosome": "4", "start_pos": 8498939, "end_pos": 8234834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043917.1", "url": "https://www.ensembl.org/id/ENSGALT00010043917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026122.1", "url": "https://www.ensembl.org/id/ENSGALP00010026122.1" } ] } }, { "isoform_ac": "A0A8V0ZC73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2/entry#A0A8V0ZC73-1", "sequence": { "sequence": "MAVSAPPVIAATSSGGGAGGSAGLFRADPLYSSPAESPRLTNSLVNSFLSAGGGGTGAGSGGGGGNECKMVDLHGVKVASFLVEGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNASSRPGRPPKRSLGVAIQENARLLPHGVPGLLSPGLISPTGLTAAAMAEAMKLQKMKLMAMNSLHGSGSQNGTESENEELNSNAGGSESSWDKDKLQSPITTGSQHSIGHPTLSGQSSLGSAHPLSPLQQNHLLTNRIDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSPLSRAGASVIKERIQDSPSPAPSLEDSQRPGSHASSHQSSSVSTSHPMTIPDLTNFSKEVQIAIPIMKPTLDKVQLAGQALPPGFPAPFLFADGLSSVETLLTNIQGLLKVAVDNARVQEKQIQQEKKELKMELCRERELRESLERQLTAELQSRATIQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATSGDGLRMLNDAGIPDMEIEHNGTQHDSAAMQGAVCTSFYCIHIYHSHINK", "length": 588, "header": "tr|A0A8V0ZC73-1|A0A8V0ZC73_CHICK Computationally mapped isoform of Dachshund family transcription factor 2 OS=Gallus gallus OX=9031 GN=DACH2 PE=3 SV=1 CANONICAL=A0A8V0Z5B2-1" }, "locus": { "chromosome": "4", "start_pos": 8498939, "end_pos": 8244032, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043893.1", "url": "https://www.ensembl.org/id/ENSGALT00010043893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026105.1", "url": "https://www.ensembl.org/id/ENSGALP00010026105.1" } ] } }, { "isoform_ac": "A0A8V0ZC98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2/entry#A0A8V0ZC98-1", "sequence": { "sequence": "MAVSAPPVIAATSSGGGAGGSAGLFRADPLYSSPAESPRLTNSLVNSFLSAGGGGTGAGSGGGGGNECKMVDLHGVKVASFLVEGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNASSRPGRPPKRSLGVAIQENARLLPHGVPGLLSPGLISPTGLTAAAMAEAMKLQKMKLMAMNSLHGSGSQNGTESENEELNSNAGGSESSWDKDKLQSPITTGSQHSIGHPTLSGQSSLGSAHPLSPLQQNHLLTNRIDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSPLSRAGASVIKERIQDSPSPAPSLEDSQRPGSHASSHQSSSVSSSPSQLDNTPDRIAMLTNSREGELIDQETGTSLKKMQKEKEEVQIAIPIMKPTLDKVQLAGQALPPGFPAPFLFADGLSSVETLLTNIQGLLKVAVDNARVQEKQIQQEKKELKMELCRERELRESLERQLTAELQSRATIQKRLKKEKKAKRKLQEALEFESKRREQVEQALKQATSGDGLRMLNDAGIPDMEIEHNGTQHDSAAMQENRTYIKPTIMY", "length": 607, "header": "tr|A0A8V0ZC98-1|A0A8V0ZC98_CHICK Computationally mapped isoform of Dachshund family transcription factor 2 OS=Gallus gallus OX=9031 GN=DACH2 PE=3 SV=1 CANONICAL=A0A8V0Z5B2-1" }, "locus": { "chromosome": "4", "start_pos": 8498939, "end_pos": 8234834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043926.1", "url": "https://www.ensembl.org/id/ENSGALT00010043926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026130.1", "url": "https://www.ensembl.org/id/ENSGALP00010026130.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395576", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B2" }, { "id": "PF02437", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02437" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SKI/SNO/DAC", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 161, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 621, "end_pos": 623 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1", "locus": {} } ], "crossref": [ { "id": "IPR053329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR39110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39110:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39110:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5B6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PLPQPAVVLLQPRHALHRAADELQVPQPRGGGGGRDGAALGVPNGAAFGVPNGAALREPNGVALAVSSGTAFRVPNGAALGVPNGAAFGVPNGAALREPNGAALGVPNGAVFGVPNGTALGVPNGTAFRVPSGAALGVPNGAAFRVPNGAALAVSNGTALGVPSGADFGVPNGAALRKPNGVALGVPNGAALRVPSSTVFRVLNGTALREPGGIALGFPNGADFGVPNGAAFRVPNGAAFGVPNGAALREPNGKALGVPNGTAFRVSSGAAFGVPNGAALREPGDIVLGVPTGAAFRVPNGAALGVPNGAAFRVPNGEAFGVPNGTAFRVPSGTAFGVPNGAAFRVPNSAALRAPSGIALGVPSGTAFDVHNGTAFGVPNGTAFGVPYSTAFGHPIPMLFGVPFATLLGNPNSALFGIPHGTVFGVPIATVFGVSNATLSGDPNTVSFGVPHGTVYGVPIAALLEVPNGAVYGVPNGTGFGVPNGTVFGVPIATVFGVSNAALSGDPNTVSFGVPHGTVYGVPIAALLGVPHGTVYGVPIATVFGVFNAILSGDPNTVSFGVPNGTGFGVPNGTVYGVPIATVFGVSNVTLSGDPNTMSFGVPDGTVYGVPIAALLGVPIAPGFGVPTAAVFGVPPGPAAPSLPADAAAAAGGLSATSLLGSPGRDPTNGSG", "length": 672, "header": "tr|A0A8V0Z5C1-1|A0A8V0Z5C1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z5C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1/entry#A0A8V0Z5B6-1", "sequence": { "sequence": "QPAVVLLQPRHALHRAADELQVPQPRGGGGGRDGAALGVPNGAAFGVPNGAALREPNGVALAVSSGTAFRVPNGAALGVPNGAAFGVPNGAALREPNGAALGVPNGAVFGVPNGTALGVPNGTAFRVPSGAALGVPNGAAFRVPNGAALAVSNGTALGVPSGADFGVPNGAALRKPNGVALGVPNGAALRVPSSTVFRVLNGTALREPGGIALGFPNGADFGVPNGAAFRVPNGAAFGVPNGAALREPNGKALGVPNGTAFRVSSGAAFGVPNGAALREPGDIVLGVPTGAAFRVPNGAALGVPNGAAFRVPNGEAFGVPNGTAFRVPSGTAFGVPNGAAFRVPNSAALRAPSGIALGVPSGTAFDVHNGTAFGVPNGTAFGVPYSTAFGHPIPMLFGVPFATLLGNPNSALFGIPHGTVFGVPIATVFGVSNATLSGDPNTVSFGVPHGTVYGVPIAALLEVPNGAVYGVPNGTVFGVSNAALSGDPNTVSFGVPHGTVYGVPIAALLGVPHGTVYGVPIATVFGVFNAILSGDPNTVSFGVPNGTGFGVPNGTVYGVPIATVFGVSNVTLSGDPNTMSFGVPDGTVYGVPIAALLGVPIAPGFGVPTAAVFGVPPGPAAPSLPADAAAAAGGLSATSLLGSPGRDPTNGSG", "length": 653, "header": "tr|A0A8V0Z5B6-1|A0A8V0Z5C1_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z5C1-1" }, "locus": { "chromosome": "22", "start_pos": 1462154, "end_pos": 1460148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048202.1", "url": "https://www.ensembl.org/id/ENSGALT00010048202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028425.1", "url": "https://www.ensembl.org/id/ENSGALP00010028425.1" } ] } }, { "isoform_ac": "A0A8V0Z5C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C1/entry#A0A8V0Z5C1-1", "sequence": { "sequence": "PLPQPAVVLLQPRHALHRAADELQVPQPRGGGGGRDGAALGVPNGAAFGVPNGAALREPNGVALAVSSGTAFRVPNGAALGVPNGAAFGVPNGAALREPNGAALGVPNGAVFGVPNGTALGVPNGTAFRVPSGAALGVPNGAAFRVPNGAALAVSNGTALGVPSGADFGVPNGAALRKPNGVALGVPNGAALRVPSSTVFRVLNGTALREPGGIALGFPNGADFGVPNGAAFRVPNGAAFGVPNGAALREPNGKALGVPNGTAFRVSSGAAFGVPNGAALREPGDIVLGVPTGAAFRVPNGAALGVPNGAAFRVPNGEAFGVPNGTAFRVPSGTAFGVPNGAAFRVPNSAALRAPSGIALGVPSGTAFDVHNGTAFGVPNGTAFGVPYSTAFGHPIPMLFGVPFATLLGNPNSALFGIPHGTVFGVPIATVFGVSNATLSGDPNTVSFGVPHGTVYGVPIAALLEVPNGAVYGVPNGTGFGVPNGTVFGVPIATVFGVSNAALSGDPNTVSFGVPHGTVYGVPIAALLGVPHGTVYGVPIATVFGVFNAILSGDPNTVSFGVPNGTGFGVPNGTVYGVPIATVFGVSNVTLSGDPNTMSFGVPDGTVYGVPIAALLGVPIAPGFGVPTAAVFGVPPGPAAPSLPADAAAAAGGLSATSLLGSPGRDPTNGSG", "length": 672, "header": "tr|A0A8V0Z5C1-1|A0A8V0Z5C1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z5C1-1" }, "locus": { "chromosome": "22", "start_pos": 1463973, "end_pos": 1463180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048209.1", "url": "https://www.ensembl.org/id/ENSGALT00010048209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028430.1", "url": "https://www.ensembl.org/id/ENSGALP00010028430.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 669, "end_pos": 671 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5B9-1", "uniprot_ac": "A0A8V0Z5B9", "uniprot_id": "A0A8V0Z5B9_CHICK", "mass": { "chemical_mass": 85291.0, "monoisotopic_mass": 85291.0 }, "refseq": { "ac": "XP_004935298", "name": "ankyrin repeat and EF-hand domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935298" }, "gene_names": [ { "name": "ANKEF1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9" } ] }, { "name": "ANKEF1", "type": "synonym", "evidence": [ { "id": "XP_004935298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935298" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and EF-hand domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_004935298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935298" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935298.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935298" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKEF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9", "locus": { "chromosome": "3", "start_pos": 13461611, "end_pos": 13475806, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018334", "url": "https://www.ensembl.org/id/ENSGALG00010018334" } ] } } ], "crossref": [ { "id": "A0A8V0Z5B9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5B9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416735", "url": "https://www.ncbi.nlm.nih.gov/gene/416735", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416735", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416735", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATDNFMW", "url": "https://omabrowser.org/oma/group/ATDNFMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5B9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24127:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24127:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004935298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPVDNRLRNLQIYKLLQCVHQKDKKQIEKLIQNGFPNLINFTEPMDGHSALSLACIKNDIDMCSFLLERGAHPDVQDKMGCTPAMKAAELGHSLVLELLAKIKADMTIVDNEGKGVLFYCILPTRRHYHCTQIALDYGADINNCSTDGKPVFLQACEQAHDIKEICLNFLERGANPNARDPVTGRTAIMEAAREGALEVVRGILERGGDINLFDNERHNAAHFAAKGGFFEILRIISAYNGDLGLIAMNGNTPLHYAAEGGFANCCKFIGQRGCDPTWTNLLAKTPRAVAKEGGFKAAATELHKIEKNFIKQSKPGAKENNPLWALRLYDWSLEHQTALLQAFEAVDQGDGTVAKDDFISVIQKWCSFVDAEQIQTIAEAHEKPDSEGINTEEFFKGFKYLQKSCLITSFGPKRKKGKKGKKRRSKKSVAVPVPICVIPKSACLLREDGFPVYMIEAVQSTADSYHINQDHPSAHPVHDDRAWYTDEPRKMYMNINFLVRAGDILSLQKAFEEGVPVDIKDKYYKTPLMAACTSGNIDVVRYLLEKGADVNATDNFMWTPLHHACYNGHLDIAELMVKAGGAIDAPAIGNATPLMRAVEICRLDIVHFLIDAGADVQTTNSNGKNALDIAKVFADSRIIDLLQNKLDNLPKVTEKKGAEKGTVAKPKMPSAPTPSEVQAVKTEPSHASLPPLEKPRLEKPAQDSVVYLNSLISSGATKKDDIAFKPRKIWTPDAATKELVRKQELLWERSTLGGDSENFESPFKRKVTE", "length": 770, "header": "tr|A0A8V0Z5B9-1|A0A8V0Z5B9_CHICK Isoform 1 of Ankyrin repeat and EF-hand domain containing 1 OS=Gallus gallus OX=9031 GN=ANKEF1 PE=4 SV=1 CANONICAL=A0A8V0Z5B9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B9/entry#A0A8V0Z5B9-1", "sequence": { "sequence": "MLPVDNRLRNLQIYKLLQCVHQKDKKQIEKLIQNGFPNLINFTEPMDGHSALSLACIKNDIDMCSFLLERGAHPDVQDKMGCTPAMKAAELGHSLVLELLAKIKADMTIVDNEGKGVLFYCILPTRRHYHCTQIALDYGADINNCSTDGKPVFLQACEQAHDIKEICLNFLERGANPNARDPVTGRTAIMEAAREGALEVVRGILERGGDINLFDNERHNAAHFAAKGGFFEILRIISAYNGDLGLIAMNGNTPLHYAAEGGFANCCKFIGQRGCDPTWTNLLAKTPRAVAKEGGFKAAATELHKIEKNFIKQSKPGAKENNPLWALRLYDWSLEHQTALLQAFEAVDQGDGTVAKDDFISVIQKWCSFVDAEQIQTIAEAHEKPDSEGINTEEFFKGFKYLQKSCLITSFGPKRKKGKKGKKRRSKKSVAVPVPICVIPKSACLLREDGFPVYMIEAVQSTADSYHINQDHPSAHPVHDDRAWYTDEPRKMYMNINFLVRAGDILSLQKAFEEGVPVDIKDKYYKTPLMAACTSGNIDVVRYLLEKGADVNATDNFMWTPLHHACYNGHLDIAELMVKAGGAIDAPAIGNATPLMRAVEICRLDIVHFLIDAGADVQTTNSNGKNALDIAKVFADSRIIDLLQNKLDNLPKVTEKKGAEKGTVAKPKMPSAPTPSEVQAVKTEPSHASLPPLEKPRLEKPAQDSVVYLNSLISSGATKKDDIAFKPRKIWTPDAATKELVRKQELLWERSTLGGDSENFESPFKRKVTE", "length": 770, "header": "tr|A0A8V0Z5B9-1|A0A8V0Z5B9_CHICK Isoform 1 of Ankyrin repeat and EF-hand domain containing 1 OS=Gallus gallus OX=9031 GN=ANKEF1 PE=4 SV=1 CANONICAL=A0A8V0Z5B9-1" }, "locus": { "chromosome": "3", "start_pos": 13474282, "end_pos": 13461829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044255.1", "url": "https://www.ensembl.org/id/ENSGALT00010044255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026323.1", "url": "https://www.ensembl.org/id/ENSGALP00010026323.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 674, "start_aa": "Thr", "end_pos": 674, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr674", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416735", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416735", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I1F9-1", "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1", "gene_name": "Ankef1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDIDMVSFLLGLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGILFYCILPTKRHYRCSLIALDHGADVNNITYEGKPVFLKACEEAHDVKEMCMTFLEKGANPNAINSSTGRTALMEASREGAVELVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYSGDMGLIGMNGNTPLHYAAMGGFADCCKYLAQRGCELKWKNLEHKTPRAVAKDGGFKAASKEIRRAERTAAKLAKPGVKNPNPIWALRLHDWSIEHEAFLREAFTFVDRGDGSVSKDDFVVTLEERQDFATPDQLLQIAQMHEKSRGSGININDFFKGTKYLSKSFVLGSFGPKKKKKSLSRKPKKGKFFLPLPVCTIPENAFPRRPDGGPPYYMIETYQNVSDCSRFNRDHPPDHPIQDDSVWYMDEPGKVFANINFITMAGDLSSLKKAFEAGIPVDMKDSSYKTPLMTACASGNLDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLIKSGAAVDAMSINNSTPLSRAIESCRLDTVKYLLDIGAKFQIENRRGHAAMDVAKAYADYRIIDMIKEKIDSLPKPLDNQKMKPKLPKLKSEGTDIKKEEETLSSVYAVPPITEEKKLSKDNVVYLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTYEVDFEDFMMPFQKNIMEKAQALEASLKL", "length": 775 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A9E7-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "Ankef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTKLGYPELINFTEPIDGLSALHLASVSNDIDMVSFLLGLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHFRCSQIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLELVRGILERGGEVNTFDNDRHNAAHFAAKGGFFDILKLLFAYSGEMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRMVAKDGGFKAASKEIRRAERTAAKLAKPGVKNPNPLWALRLHDWSIEHESSLREAFSFVDRGDGVVSKDDFVLALEERQEFATPEQLLSVAQMHEKSRGGGVNINDFFKGTKYLSKSFVLGSFGPKKKKKGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMVETYQNVTDTNRFNRDHPPEHPIQDDSEWYIDDPNRVFANINFITKAGDLASLKKAFEAGIPVDMKDNTYKTPLMTACASGNIDVVKFLLERGANVNATDNFLWTPLHFACHAGQQDIVELLVQSGAVIDASSINNSTPLSRAIESCRLDTVKYLLDNGAKFQTENRKGHAAMDIAKAYADYRIIDMIKEKLDELPKPTDNQKMKSKLPKLKTEGTDVKKEEGTLSSIYTVPAITEEKKIHRDNVVYLNSLITSGFTKKVDITFIPKRIWSPEATTAQLIRKRELRRERFTYEVDFEDFMMPFQKNITEKAQALESMLKN", "length": 775 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B993-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "ANKEF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTRLGYPELINFTDPVNGNSALHLASVSNDIDMVSFLLSLGAHPDVQDKMGCTPTMRAAELGHELSMEILAKAKADMTVVDNEGKGILFYCILPTKRHYRCALIALEHGADVNNCTCEGKPIFLRACEEAHDVKDVCLTFLEKGANPNAINTSTGRTALMEASREGVTELVRGILERGGDVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIAMNGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRNLAKEGGFKAASKEIRRAEQIANKLARPGVKNPNPHLFLRLHDWSVEHETFLREAFSFVDRGDGTVTKEDFVLTLEERQDFVNSEQLAAIAQLHEKVRGGGVNINEFFKGTRYLSKSYVLGSYGPKKKKKGMAKRARVGKFVFPLPICIIPDHVFPRRSDGGPPYYMIETYKNVTDCNRFNRDHPPEHPIQDDSAWYIDDPGKVFSNINFITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACATGNIDAVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKSGAVVDALSINNSTPLSRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADSRIIGLIKEKLDNLPKPAENQKPKGKPQPKAKTEGPEIKKEEETLSAIYTVPAIVEDKKMRKDNVVYLNSLITSGYTKKVDITFIPQRIWSPEATTAELIRMRELRRERLTYEVDFDDFMMPFQKHITERAQAVEASFKM", "length": 776 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SBK5-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "ANKEF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTRLGYPELINFTDPINGHSALHLASVSNDIDMVSFLLNLGAHPDVQDGMGCTPAMRAAELGHELSMEILAKAKADMTIVDNEGKGILFYCILPTKRHYRCTLIALEHGADVNNCTYEGKPIFLRACEEAHDVKDVCLTLLEKGANPNAINTSTGRTALMEASREGVIELVRGILERGGEVNAFDKDRHHAAHFAAKGGFFDILKLLFAYDGDMGLIAMNGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRALAKEGGFRAASKEIQQAERIANKLARPGAKNPNPQLYLRLHDWSVEHETFLREAFSFVDRGDGTVTKEDFVLALEERQDFVDSEQLAVIAQLHEKVRGGGVNINDFFKGTKYLSKSYVLGSFGLKRKKKGMAKRAKKGKLVLPLPICIIPDHVFPRRSDGGLPYYMIETYQNVTDCNRFNRDHPPEHPIQDDSAWYIDDPGKAFSNINFITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIAELLVKSGAVVDALSINNSTPLSRAIESCSLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRVIGLIKEKMDNLPKPAENQKPKGKPSLKVKTEGPEIKKEEERLSSIYTIPTVVQEKKMHKDNVVYLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRREKFTYEVDFDEFMMPFQKNITEKAQALEAAFRT", "length": 776 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D2J7-1", "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1", "gene_name": "Ankef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVDRGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKKVDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFEDFMMPFQKNITEKAQALEATLKN", "length": 775 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NU02-1", "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1", "gene_name": "ANKEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLDRGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTHEVDFDDFMMPFQKNITEKARALEAALKT", "length": 776 }, "evidence": [ { "id": "A0A8V0Z5B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5B9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 674 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5C8-1", "uniprot_ac": "A0A8V0Z5C8", "uniprot_id": "A0A8V0Z5C8_CHICK", "mass": { "chemical_mass": 126299.0, "monoisotopic_mass": 126299.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "BTB/POZ domain-containing protein 7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8#function" }, { "database": "UniProtKB", "id": "ARBA00056723", "url": "https://www.uniprot.org/uniprotkb/ARBA00056723#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5C8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5C8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16064:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16064:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1121, "header": "tr|A0A8V0Z5C8-1|A0A8V0Z5C8_CHICK Isoform 1 of BTB/POZ domain-containing protein 7 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z5C8-1" }, "locus": { "chromosome": "5", "start_pos": 44616766, "end_pos": 44587640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040771.1", "url": "https://www.ensembl.org/id/ENSGALT00010040771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023735.1", "url": "https://www.ensembl.org/id/ENSGALP00010023735.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "morphogenesis of a branching epithelium", "id": "GO:0061138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 828, "end_pos": 830, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"A0A8V0Z6F7-1", "uniprot_ac": "A0A8V0Z6F7", "uniprot_id": "A0A8V0Z6F7_CHICK", "mass": { "chemical_mass": 119464.0, "monoisotopic_mass": 119464.0 }, "refseq": { "ac": "XP_040562614", "name": "IQ domain-containing protein H isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562614" }, "gene_names": [ { "name": "IQCH", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7" } ] }, { "name": "IQCH", "type": "synonym", "evidence": [ { "id": "XP_040562614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562614" } ] } ], "protein_names": [ { "name": "IQ domain-containing protein H isoform X5", "type": "synonym", "evidence": [ { "id": "XP_040562614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562614" } ] }, { "name": "IQ motif containing H", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IQCH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7", "locus": { "chromosome": "10", "start_pos": 18958619, "end_pos": 18898971, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018192", "url": "https://www.ensembl.org/id/ENSGALG00010018192" } ] } } ], "crossref": [ { "id": "A0A8V0Z6F7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6F7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415554", "url": "https://www.ncbi.nlm.nih.gov/gene/415554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4V0", "url": "https://www.orthodb.org/?gene=A0A8V0Z4V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5E5", "url": "https://www.orthodb.org/?gene=A0A8V0Z5E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6F7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14465:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14465:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040562614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGTAGQGERVQEDLHKLKDQVKNISLKGNVRAEGIGDLETATERTESGLRKHTENYLSAVSREVLTISAAGNEEVRSKQLPGWGLPRGASENQLVLPPVPAEPMTAQACSKAALRLSPGSQKQLEMDVKIMLDPENINKKAVLKQQGYETRLPRITKRKPAPTNSQKGVKGHTTSQLWVLPASPRVDSPLPLLEQDMKKDILSLTERRLIPPAAKITFQTPPVVFKAAPLHEFHRQHKKSAVGEVSSKVEPVSTEPSAFPSSKEASGGSSSKGNTAPLLPSSSLDSTRKSKPAHAYPAQQLQCELQAAQTQDPSPDCDIAVYHGTIDQTAPGFLAFKQRYCLSWGSVVHFLEHTEKLLKDYAVPLATISCQKLVEAASDFVLNENPTKSDILSVIKNQSTVEKILNRPGQRYKGQGGPEMAAVKIQATWRRHQARRAYVRLRQQQWASGVIAISWLLRSHMARVKKSLKESRQRHLENFYIRAKHLAANWNRIRTSRRTIIHIPSLGYSQCIRERTPDLALQQNLQLGRLCDILDANVDVIYICPLHLSEELLQYYNKLLGLQAAVRSGNPEDMSDLQDRFRILTPEAINSFPRHHMCLATQLKYSPKTIQRIKILIQSRDAYIIGGVPHKDDLAVADMLNVPILGSVPEVAHLYSTKSGSKRIFASAYVPTPPGESDIYSHEQLIGALSQLVVDNMEVRRWLFKMNDEYGGNGTAFCDIILHLECYHWVLKERQKHSPETWSKKWAHEPALVKISQELPGLLAQHVQPVNEKRFPTWEKFLQTFLSQGGVIEAFPLSENVTNLTVDMLIEPTGEIKVVSSGDQLHADGPLRSSGTTIPQRSVDPAVLNSLCLKIGEACKSKGVLGYFSVDFVTFIHPQTMEQQVWATDLDLCYSDQLALTQLTLYVSDGNLDCCSGLSEVPLGSRKLKSQGTQHKETKMPSPGSSRCAVASSQLRHSSLSVIYYSVLLQMCKAHGIGFDLQENQGTVFILYDDQKRYRLGMITIGEDLQGVLMTFARNLFIIHQEISAPNMQGETNFKMAIQDIEAILGVTAENKLKWEEEHPSKADALKE", "length": 1073, "header": "tr|A0A8V0Z6F7-1|A0A8V0Z6F7_CHICK Isoform 1 of IQ motif containing H OS=Gallus gallus OX=9031 GN=IQCH PE=4 SV=1 CANONICAL=A0A8V0Z6F7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7/entry#A0A8V0Z4V0-1", "sequence": { "sequence": "MTAQACSKAALRLSPGSQQLEMDVKIMLDPENINKKAVLKQQGYETRLPRITKRKPAPTNSQKGVKGHTTSQLWVLPASPRVDSPLPLLEQDMKKDILSLTERRLIPPAAKITFQTPPVVFKAAPLHEFHRQHKKSAVGEVSSKVEPVSTEPSAFPSSKEASGGSSSKGNTAPLLPSSSLDSTRKSKPAHAYPAQQLQCELQAAQTQDPSPDCDIAVYHGTIDQTAPGFLAFKQRYCLSWGSVVHFLEHTEKLLKDYAVPLATISCQKLVEAASDFVLNENPTKSDILSVIKNQSTVEKILNRPGQRYKGQGGPEMAAVKIQATWRRHQARRAYVRLRQQQWASGVIAISWLLRSHMARVKKSLKESRQRHLENFYIRAKHLAANWNRIRTSRRTIIHIPSLGYSQCIRERTPDLALQQNLQLGRLCDILDANVDVIYICPLHLSEELLQYYNKLLGLQAAVRSGNPEDMSDLQDRFRILTPEAINSFPRHHMCLATQLKYSPKTIQRIKILIQSRDAYIIGGVPHKDDLAVADMLNVPILGSVPEVAHLYSTKSGSKRIFASAYVPTPPGESDIYSHEQLIGALSQLVVDNMEVRRWLFKMNDEYGGNGTAFCDIILHLECYHWVLKERQKHSPETWSKKWAHEPALVKISQELPGLLAQHVQPVNEKRFPTWEKFLQTFLSQGGVIEAFPLSENVTNLTVDMLIEPTGEIKVVSSGDQLHADGPLRSSGTTIPQRSVDPAVLNSLCLKIGEACKSKGVLGYFSVDFVTFIHPQTMEQQVWATDLDLCYSDQLALTQLTLYVSDGNLDCCSGLSEVPLGSRKLKSQGTQHKETKMPSPGSSRCAVASSQLRHSSLSVIYYSVLLQMCKAHGIGFDLQENQGTVFILYDDQKRYRLGMITIGEDLQGVLMTFARNLFIIHQEISAPNMQGETNFKMAIQDIEAILGVTAENKLKWEEEHPSKADALKE", "length": 968, "header": "tr|A0A8V0Z4V0-1|A0A8V0Z4V0_CHICK Computationally mapped isoform of IQ motif containing H OS=Gallus gallus OX=9031 GN=IQCH PE=4 SV=1 CANONICAL=A0A8V0Z6F7-1" }, "locus": { "chromosome": "10", "start_pos": 18957320, "end_pos": 18900284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043968.1", "url": "https://www.ensembl.org/id/ENSGALT00010043968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026146.1", "url": "https://www.ensembl.org/id/ENSGALP00010026146.1" } ] } }, { "isoform_ac": "A0A8V0Z5E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7/entry#A0A8V0Z5E5-1", "sequence": { "sequence": "MKQLEMDVKIMLDPENINKKAVLKQQGYETRLPRITKRKPAPTNSQKGVKGHTTSQLWVLPASPRVDSPLPLLEQDMKKDILSLTERRLIPPAAKITFQTPPVVFKAAPLHEFHRQHKKSAVGEVSSKVEPVSTEPSAFPSSKEASGGSSSKGNTAPLLPSSSLDSTRKSKPAHAYPAQQLQCELQAAQTQDPSPDCDIAVYHGTIDQTAPGFLAFKQRYCLSWGSVVHFLEHTEKLLKDYAVPLATISCQKLVEAASDFVLNENPTKSDILSVIKNQSTVEKILNRPGQRYKGQGGPEMAAVKIQATWRRHQARRAYVRLRQQQWASGVIAISWLLRSHMARVKKSLKESRQRHLENFYIRAKHLAANWNRIRTSRRTIIHIPSLGYSQCIRERTPDLALQQNLQLGRLCDILDANVDVIYICPLHLSEELLQYYNKLLGLQAAVRSGNPEDMSDLQDRFRILTPEAINSFPRHHMCLATQLKYSPKTIQRIKILIQSRDAYIIGGVPHKDDLAVADMLNVPILGSVPEVAHLYSTKSGSKRIFASAYVPTPPGESDIYSHEQLIGALSQLVVDNMEVRRWLFKMNDEYGGNGTAFCDIILHLECYHWVLKERQKHSPETWSKKWAHEPALVKISQELPGLLAQHVQPVNEKRFPTWEKFLQTFLSQGGVIEAFPLSENVTNLTVDMLIEPTGEIKVVSSGDQLHADGPLRSSGTTIPQRSVDPAVLNSLCLKIGEACKSKGVLGYFSVDFVTFIHPQTMEQQVWATDLDLCYSDQLALTQLTLYVSDGNLDCCSGLSEVPLGSRKLKSQGTQHKETKMPSPGSSRCAVASSQLRHSSLSVIYYSVLLQMCKAHGIGFDLQENQGTVFILYDDQKRYRLGMITIGEDLQGVLMTFARNLFIIHQEISAPNMQGETNFKMAIQDIEAILGVTAENKLKWEEEHPSKADALKE", "length": 952, "header": "tr|A0A8V0Z5E5-1|A0A8V0Z6F7_CHICK Computationally mapped isoform of IQ motif containing H OS=Gallus gallus OX=9031 GN=IQCH PE=4 SV=1 CANONICAL=A0A8V0Z6F7-1" }, "locus": { "chromosome": "10", "start_pos": 18957320, "end_pos": 18899875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043972.1", "url": "https://www.ensembl.org/id/ENSGALT00010043972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026148.1", "url": "https://www.ensembl.org/id/ENSGALP00010026148.1" } ] } }, { "isoform_ac": "A0A8V0Z6F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7/entry#A0A8V0Z6F7-1", "sequence": { "sequence": "MAGTAGQGERVQEDLHKLKDQVKNISLKGNVRAEGIGDLETATERTESGLRKHTENYLSAVSREVLTISAAGNEEVRSKQLPGWGLPRGASENQLVLPPVPAEPMTAQACSKAALRLSPGSQKQLEMDVKIMLDPENINKKAVLKQQGYETRLPRITKRKPAPTNSQKGVKGHTTSQLWVLPASPRVDSPLPLLEQDMKKDILSLTERRLIPPAAKITFQTPPVVFKAAPLHEFHRQHKKSAVGEVSSKVEPVSTEPSAFPSSKEASGGSSSKGNTAPLLPSSSLDSTRKSKPAHAYPAQQLQCELQAAQTQDPSPDCDIAVYHGTIDQTAPGFLAFKQRYCLSWGSVVHFLEHTEKLLKDYAVPLATISCQKLVEAASDFVLNENPTKSDILSVIKNQSTVEKILNRPGQRYKGQGGPEMAAVKIQATWRRHQARRAYVRLRQQQWASGVIAISWLLRSHMARVKKSLKESRQRHLENFYIRAKHLAANWNRIRTSRRTIIHIPSLGYSQCIRERTPDLALQQNLQLGRLCDILDANVDVIYICPLHLSEELLQYYNKLLGLQAAVRSGNPEDMSDLQDRFRILTPEAINSFPRHHMCLATQLKYSPKTIQRIKILIQSRDAYIIGGVPHKDDLAVADMLNVPILGSVPEVAHLYSTKSGSKRIFASAYVPTPPGESDIYSHEQLIGALSQLVVDNMEVRRWLFKMNDEYGGNGTAFCDIILHLECYHWVLKERQKHSPETWSKKWAHEPALVKISQELPGLLAQHVQPVNEKRFPTWEKFLQTFLSQGGVIEAFPLSENVTNLTVDMLIEPTGEIKVVSSGDQLHADGPLRSSGTTIPQRSVDPAVLNSLCLKIGEACKSKGVLGYFSVDFVTFIHPQTMEQQVWATDLDLCYSDQLALTQLTLYVSDGNLDCCSGLSEVPLGSRKLKSQGTQHKETKMPSPGSSRCAVASSQLRHSSLSVIYYSVLLQMCKAHGIGFDLQENQGTVFILYDDQKRYRLGMITIGEDLQGVLMTFARNLFIIHQEISAPNMQGETNFKMAIQDIEAILGVTAENKLKWEEEHPSKADALKE", "length": 1073, "header": "tr|A0A8V0Z6F7-1|A0A8V0Z6F7_CHICK Isoform 1 of IQ motif containing H OS=Gallus gallus OX=9031 GN=IQCH PE=4 SV=1 CANONICAL=A0A8V0Z6F7-1" }, "locus": { "chromosome": "10", "start_pos": 18957320, "end_pos": 18898998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043979.1", "url": "https://www.ensembl.org/id/ENSGALT00010043979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026152.1", "url": "https://www.ensembl.org/id/ENSGALP00010026152.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 673, "start_aa": "Thr", "end_pos": 673, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr673", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F7" }, { "id": "PF24923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IQCH-like ATP-grasp", "eco_id": "ECO_0000259", "start_pos": 650, "end_pos": 915, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 673 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 804, "end_pos": 806 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5F7-1", "uniprot_ac": "A0A8V0Z5F7", "uniprot_id": "A0A8V0Z5F7_CHICK", "mass": { "chemical_mass": 55608.0, "monoisotopic_mass": 55608.0 }, "refseq": {}, "gene_names": [ { "name": "PLD4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ] } ], "protein_names": [ { "name": "spleen exonuclease", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7/entry#names_and_taxonomy" } ] }, { "name": "3.1.16.1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7", "locus": { "chromosome": "5", "start_pos": 51311326, "end_pos": 51298737, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019994", "url": "https://www.ensembl.org/id/ENSGALG00010019994" } ] } } ], "crossref": [ { "id": "A0A8V0Z5F7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5F7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09145", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09145", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5F7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10185:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10185:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "81319", "url": "https://www.rhea-db.org/rhea/81319", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81375", "url": "https://www.rhea-db.org/rhea/81375", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81379", "url": "https://www.rhea-db.org/rhea/81379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82335", "url": "https://www.rhea-db.org/rhea/82335", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82563", "url": "https://www.rhea-db.org/rhea/82563", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "82567", "url": "https://www.rhea-db.org/rhea/82567", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQISGVILMLGFVALMAVYFMRADSTIDRKGEETVVSIYQEMEEEELYGDLQRATVTEEDTNRSNDSCSFELVESVPYDLAFEINSTAAKPLYRAWMNLLDIAQEEIHVASYYWSLTGKDISVNDSSSKQGEEILKRFERLLAENVSVYIAASVPTLAMNSTDLEFLERKGAHIKKIDFGRLTGGVLHSKFWIIDMKHIYIGSANMDWRSLSQVKEFGAVIYNCSCLAKDLWKTFRTYWDLGHASATIPSPWPQNYSTYINNSRPLEIEFNGTLTKVYFSASPPAFCPEGRTHDLFAIISVISAAHKFVYISVMDYFPTSRFVHPERYWPVIDNALRRVAFNYRVQIRLLVSCWTHTDPSMLHYLRSLSALNNPHTHISVTVKLFIVPVLNHTNIPHGRVNHNKYMVTDKAAYIGTSNWSEDYFTNTAGVGLIIKQSPTNLQRRQQPVQEQLKSIFERDWNSKYSVNVEDVQGQKDCNWRDRL", "length": 484, "header": "tr|A0A8V0Z5F7-1|A0A8V0Z5F7_CHICK Isoform 1 of spleen exonuclease OS=Gallus gallus OX=9031 GN=PLD4 PE=3 SV=1 CANONICAL=A0A8V0Z5F7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7/entry#A0A8V0Z5F7-1", "sequence": { "sequence": "MFQISGVILMLGFVALMAVYFMRADSTIDRKGEETVVSIYQEMEEEELYGDLQRATVTEEDTNRSNDSCSFELVESVPYDLAFEINSTAAKPLYRAWMNLLDIAQEEIHVASYYWSLTGKDISVNDSSSKQGEEILKRFERLLAENVSVYIAASVPTLAMNSTDLEFLERKGAHIKKIDFGRLTGGVLHSKFWIIDMKHIYIGSANMDWRSLSQVKEFGAVIYNCSCLAKDLWKTFRTYWDLGHASATIPSPWPQNYSTYINNSRPLEIEFNGTLTKVYFSASPPAFCPEGRTHDLFAIISVISAAHKFVYISVMDYFPTSRFVHPERYWPVIDNALRRVAFNYRVQIRLLVSCWTHTDPSMLHYLRSLSALNNPHTHISVTVKLFIVPVLNHTNIPHGRVNHNKYMVTDKAAYIGTSNWSEDYFTNTAGVGLIIKQSPTNLQRRQQPVQEQLKSIFERDWNSKYSVNVEDVQGQKDCNWRDRL", "length": 484, "header": "tr|A0A8V0Z5F7-1|A0A8V0Z5F7_CHICK Isoform 1 of spleen exonuclease OS=Gallus gallus OX=9031 GN=PLD4 PE=3 SV=1 CANONICAL=A0A8V0Z5F7-1" }, "locus": { "chromosome": "5", "start_pos": 51310874, "end_pos": 51298844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048278.1", "url": "https://www.ensembl.org/id/ENSGALT00010048278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028467.1", "url": "https://www.ensembl.org/id/ENSGALP00010028467.1" } ] } }, { "isoform_ac": "A0A8V0ZCQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7/entry#A0A8V0ZCQ3-1", "sequence": { "sequence": "MAGAWFPARVTAACFTLYNCCCSFELVESVPYDLAFEINSTAAKPLYRAWMNLLDIAQEEIHVASYYWSLTGKDISVNDSSSKQGEEILKRFERLLAENVSVYIAASVPTLAMNSTDLEFLERKGAHIKKIDFGRLTGGVLHSKFWIIDMKHIYIGSANMDWRSLSQVKEFGAVIYNCSCLAKDLWKTFRTYWDLGHASATIPSPWPQNYSTYINNSRPLEIEFNGTLTKVYFSASPPAFCPEGRTHDLFAIISVISAAHKFVYISVMDYFPTSRFVHPERYWPVIDNALRRVAFNYRVQIRLLVSCWTHTDPSMLHYLRSLSALNNPHTHISVTVKLFIVPVLNHTNIPHGRVNHNKYMVTDKAAYIGTSNWSEDYFTNTAGVGLIIKQSPTNLQRRQQPVQEQLKSIFERDWNSKYSVNVEDVQGQKDCNWRDRL", "length": 437, "header": "tr|A0A8V0ZCQ3-1|A0A8V0ZCQ3_CHICK Computationally mapped isoform of spleen exonuclease OS=Gallus gallus OX=9031 GN=PLD4 PE=3 SV=1 CANONICAL=A0A8V0Z5F7-1" }, "locus": { "chromosome": "5", "start_pos": 51310874, "end_pos": 51303292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048275.1", "url": "https://www.ensembl.org/id/ENSGALT00010048275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028465.1", "url": "https://www.ensembl.org/id/ENSGALP00010028465.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "intralumenal vesicle formation", "id": "GO:0070676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "regulation of cytokine production involved in inflammatory response", "id": "GO:1900015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 7 signaling pathway", "id": "GO:0034156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "negative regulation of toll-like receptor 9 signaling pathway", "id": "GO:0034164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" }, { "name": "single-stranded DNA 5'-3' DNA exonuclease activity", "id": "GO:0045145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81319", "name": "", "equation": "a ribonucleoside 3'-phosphate-2'-3'-cyclophospho-GMP + H2O = a ribonucleoside 3'-phosphate + 2',3'-cyclophospho-GMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "81319", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81319" } ] }, { "id": "81375", "name": "", "equation": "a 5'-end 5'-dephospho-ribonucleotidyl-ribonucleotide-RNA + H2O = a ribonucleoside 3'-phosphate + a 5'-end dephospho-ribonucleoside-RNA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "81375", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81375" } ] }, { "id": "81379", "name": "", "equation": "a 5'-end 5'-dephospho-2'-deoxyribonucleotidyl-2'-deoxyribonucleotide in single-stranded DNA + H2O = a 5'-end dephospho-2'-deoxyribonucleoside in single-stranded DNA + a 2'-deoxyribonucleoside 3'-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "81379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81379" } ] }, { "id": "82335", "name": "", "equation": "a 5'-end 5'-phospho-2'-deoxyribonucleotide in single-stranded DNA + H2O = a 5'-end 5'-dephospho-2'-deoxyribonucleotide in single-stranded DNA + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "82335", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82335" } ] }, { "id": "82563", "name": "", "equation": "an (R,S)-glycero-3-phospho-(3'-acyl-1'-glycerol) + a 1-acyl-sn-glycerol = a 3-acyl-sn-glycero-1-phospho-(3'-acyl-1'-sn-glycerol) + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "82563", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82563" } ] }, { "id": "82567", "name": "", "equation": "3-lyso-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + 1-(9Z-octadecenoyl)-sn-glycerol = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z5F7-1" ], "evidence": [ { "id": "82567", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/82567" } ] }, { "id": "R-GGA-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-2023856" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZKY1-1", "A0A8V0Z5F7-1" ], "evidence": [ { "id": "R-GGA-1855214", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855214" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2023856", "participant_name": "PI(4,5)P2 [endoplasmic reticulum membrane]", "crossref": [ { "id": "58456", "database": "ChEBI", "url": "" }, { "id": "C04637", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z5F7", "gene_name": "PLD4", "activity": [ { "ec_number": "3.1.16.1", "activity": "Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates.", "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ] }, { "ec_number": "3.1.16.1", "activity": "", "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" } ] } ] }, { "uniprot_ac": "A0A8V0ZKY1", "gene_name": "PLCD4", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY1" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A8V0ZKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F7" }, { "id": "PS50035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLD phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 211, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.16.1", "ec_name": "Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates.", "evidence": [] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"MFPACFHLLAPKSTPFPLLFLGGLSGAGICGLGGGRRVTALPAPVGFEFSRSQRSVLPFLAPGLPRSEPGEAGPPLGSGGSGGGRFVRADALAAARPRGPAAAPPAGPPLFVPEFGAFPGWEKAPGRVLGVSGRVLGPQQPFRPTNRGAVGRGGTAWRGGWRNARRDPWKMSNPRNGDTKPPCLPRNGLVKIPTQPNGLGSASITKGTPAVKNRLCQPSSVPAILSPALAPRSDLPIPSLASPLSLAALAGVSSPPGTSLVALNSSEATPGSEHPSPERLPGSPSERQLVVDEKILNRLFWYFSACEKCVLAQVCKAWRRVLYQPKFWVGLTPVLHTKELYNILPGGEKEFVSLQGFAVRGFDGFCLVGVSDLDICEFIDNYPLSKKGVKSMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLNARITALSVSDCINVADDAIAAISQLLPNLAELNLQAYHVTDTALAYFTAKQGYTTHTLRLNSCWEITNHGVVNMVHSLPNLSVLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYIACDLHKLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLGMGSLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPCCMVIE", "length": 673, "header": "tr|A0A8V0Z710-1|A0A8V0Z710_CHICK Isoform 1 of F-box/LRR-repeat protein 16 OS=Gallus gallus OX=9031 GN=FBXL16 PE=4 SV=1 CANONICAL=A0A8V0Z710-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z710/entry#A0A8V0Z5G9-1", "sequence": { "sequence": 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"ENSGALP00010026373.1", "url": "https://www.ensembl.org/id/ENSGALP00010026373.1" } ] } }, { "isoform_ac": "A0A8V0Z710-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z710/entry#A0A8V0Z710-1", "sequence": { "sequence": "MFPACFHLLAPKSTPFPLLFLGGLSGAGICGLGGGRRVTALPAPVGFEFSRSQRSVLPFLAPGLPRSEPGEAGPPLGSGGSGGGRFVRADALAAARPRGPAAAPPAGPPLFVPEFGAFPGWEKAPGRVLGVSGRVLGPQQPFRPTNRGAVGRGGTAWRGGWRNARRDPWKMSNPRNGDTKPPCLPRNGLVKIPTQPNGLGSASITKGTPAVKNRLCQPSSVPAILSPALAPRSDLPIPSLASPLSLAALAGVSSPPGTSLVALNSSEATPGSEHPSPERLPGSPSERQLVVDEKILNRLFWYFSACEKCVLAQVCKAWRRVLYQPKFWVGLTPVLHTKELYNILPGGEKEFVSLQGFAVRGFDGFCLVGVSDLDICEFIDNYPLSKKGVKSMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLNARITALSVSDCINVADDAIAAISQLLPNLAELNLQAYHVTDTALAYFTAKQGYTTHTLRLNSCWEITNHGVVNMVHSLPNLSVLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYIACDLHKLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLGMGSLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPCCMVIE", "length": 673, "header": "tr|A0A8V0Z710-1|A0A8V0Z710_CHICK Isoform 1 of F-box/LRR-repeat protein 16 OS=Gallus gallus OX=9031 GN=FBXL16 PE=4 SV=1 CANONICAL=A0A8V0Z710-1" }, "locus": { "chromosome": "14", "start_pos": 13184151, "end_pos": 13166967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044328.1", "url": "https://www.ensembl.org/id/ENSGALT00010044328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026374.1", "url": "https://www.ensembl.org/id/ENSGALP00010026374.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 655, "start_aa": "Thr", "end_pos": 655, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr655", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z710", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z710" } ], "pmid": "" }, { "name": "SCF ubiquitin 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266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z710", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z710" }, { "id": "PF25372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box/LRR-repeat protein 15-like leucin rich repeat", "eco_id": "ECO_0000259", "start_pos": 516, "end_pos": 637, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 269, 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"https://www.uniprot.org/uniprotkb/A0A8V0Z5K8/entry#A0A8V0ZD14-1", "sequence": { "sequence": "MWWRDGPGRGRSGLPARGLRARPWRRTGKQNGVRAAGERRPSRPPAEGSARDGGAGPCRALRRSRRRGGAGRRGEPRGDRVCQQPGLSLWVPFQNAATAVTNLYKESVDAHQRSFDVGIQIGYQRRNKDVLAWVKKRRRTIRREDLISFLCGKVPPPRNSRAPPRLTVVSPNRATSTETSSSVETDLQPFREAIALHGLSGAMASISVRSSTPGSPTHVSSGSNASRRRNGLHDVDLNTFISEEMALHLDNGGTRKRTSAQCGDVITDSPTHKRNRMI", "length": 278, "header": "tr|A0A8V0ZD14-1|A0A8V0ZD14_CHICK Computationally mapped isoform of HUWE1 associated protein modifying stress responses OS=Gallus gallus OX=9031 GN=C16orf72 PE=4 SV=1 CANONICAL=A0A8V0Z5K8-1" }, "locus": { "chromosome": "14", "start_pos": 9883415, "end_pos": 9871389, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044375.1", "url": "https://www.ensembl.org/id/ENSGALT00010044375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026407.1", "url": "https://www.ensembl.org/id/ENSGALP00010026407.1" } ] } }, { "isoform_ac": "E1BV25-1", "url": 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z779-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z779-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAEALDELAGQLQGEALGGRGLLQLAATTGLAAYAVWAAVLMPGFRRVPLHLQVPYVPSSAQQVANVMGLLRGRTGKTADLGSGDGRLVIEAYKQGLQPAVGYELNPWLLWLARYRARRAGYQGKVSFLKQDLWKANLSDCYNVIVFLAPSVPPLAAKLLAELPDEARVVAGRFPFPSWTPSSTIGQGLEQAWAYDMKEVRRAARRGTAGCAL", "length": 214, "header": "tr|A0A8V0Z5N7-1|A0A8V0Z5N7_CHICK Isoform 1 of Family with sequence similarity 173 member A OS=Gallus gallus OX=9031 GN=FAM173A PE=3 SV=1 CANONICAL=A0A8V0Z5N7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7/entry#A0A8V0Z5N7-1", "sequence": { "sequence": "MDAEALDELAGQLQGEALGGRGLLQLAATTGLAAYAVWAAVLMPGFRRVPLHLQVPYVPSSAQQVANVMGLLRGRTGKTADLGSGDGRLVIEAYKQGLQPAVGYELNPWLLWLARYRARRAGYQGKVSFLKQDLWKANLSDCYNVIVFLAPSVPPLAAKLLAELPDEARVVAGRFPFPSWTPSSTIGQGLEQAWAYDMKEVRRAARRGTAGCAL", "length": 214, "header": "tr|A0A8V0Z5N7-1|A0A8V0Z5N7_CHICK Isoform 1 of Family with sequence similarity 173 member A OS=Gallus gallus OX=9031 GN=FAM173A PE=3 SV=1 CANONICAL=A0A8V0Z5N7-1" }, "locus": { "chromosome": "14", "start_pos": 13191649, "end_pos": 13190010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044430.1", "url": "https://www.ensembl.org/id/ENSGALT00010044430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026443.1", "url": "https://www.ensembl.org/id/ENSGALP00010026443.1" } ] } }, { "isoform_ac": "A0A8V0Z779-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7/entry#A0A8V0Z779-1", "sequence": { "sequence": "MDAEALDELAGQLQGEALGGRGLLQLAATTGLAAYAVWAAVLMPGFRRVPLHLQVIEAYKQGLQPAVGYELNPWLLWLARYRARRAGYQGKVSFLKQDLWKANLSDCYNVIVFLAPSVKPPLAAKLLAELPDEARVVAGRFPFPSWTPSSTIGQGLEQAWAYDMKEVRRAARRGTAGCAL", "length": 180, "header": "tr|A0A8V0Z779-1|A0A8V0Z779_CHICK Computationally mapped isoform of Family with sequence similarity 173 member A OS=Gallus gallus OX=9031 GN=FAM173A PE=3 SV=1 CANONICAL=A0A8V0Z5N7-1" }, "locus": { "chromosome": "14", "start_pos": 13191649, "end_pos": 13190010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044426.1", "url": "https://www.ensembl.org/id/ENSGALT00010044426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026439.1", "url": "https://www.ensembl.org/id/ENSGALP00010026439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7" } ], "pmid": "" }, { "name": "regulation of mitochondrial ATP synthesis coupled proton transport", "id": "GO:1905706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N7" }, { "id": "PF28400", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28400" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ANTKMT N-terminal", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 50, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5Q3-1", "uniprot_ac": "A0A8V0Z5Q3", "uniprot_id": "A0A8V0Z5Q3_CHICK", "mass": { "chemical_mass": 163418.0, "monoisotopic_mass": 163418.0 }, "refseq": {}, "gene_names": [ { "name": "UACA", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3" } ] } ], "protein_names": [ { "name": "Uveal autoantigen with coiled-coil domains and ankyrin repeats", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UACA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3", "locus": { "chromosome": "10", "start_pos": 19635329, "end_pos": 19663925, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020056", "url": "https://www.ensembl.org/id/ENSGALG00010020056" } ] } } ], "crossref": [ { "id": "415569", "url": "https://www.ncbi.nlm.nih.gov/gene/415569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415569", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCHEMEK", "url": "https://omabrowser.org/oma/group/KCHEMEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCE2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZCZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD05", "url": "https://www.orthodb.org/?gene=A0A8V0ZD05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKARAAVCIPWEKKSVLHLHAVKWNHVLVCVMLVVAVKKHEESQEQQSVVQPALQCSPVQLNTDWNKYDDRLMKAAERGDVEKVSSILAKKGVSPTKLDVEGRSAFHVVASKGNLDCLNTILIHGVDITATDAAGRNALHLAAKYGHALCLQKLLQYNCPTENVDLQGRTALHDAAMSDCSSSIQLLCDHGASVNAKDGDGRTPLVLATQMCRPTVCQLLIDRGADVNARDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLVDGLGHDCAYYARIGDNIDILALIKAAVEDSSKARDTMKRGQPEQKMNNMSQKWNRLHAQEEVNVKLYQKEHNAQELELENQDLKDRMREVQEEQRMLLDRISGLQLQLTEKDELKKILTTKEKQQEESLRTIEALKAKLKYYEVDLVGSGSNFSNRKEDLLKQGQVFAVESQSRSMLRPLELSLPHQSPNSERETLKKELDNVRTCYGAAKEEISKLQRELSHKVSECKALASECERTKEESDGQIKQLEDALKDVQKRMFESEGKVKQMQTHFLALKDHLTNEAASGNSKLTEELKDQLKEMKTKYEGASAEVGKLRNQIKQNELLVAEFKRDEGRLVEENKRLQKELVKLEMERDKRERSVMELEGQLKETAAKLARSVTSEKFENMKSSLSNEVNEKARKLAEIEGESEKLQAEIWALKRECDSQKAKLAQHVKPEDHEQMRSGFEQKHEELEGRISELSQKNQTLQKELERFQTDNKMLKQQLQVLKTEIKSQNVPLKIHEELKKTSDVTVGDLTKKLLEITRKYNESQAEAERLLAEKNSLSEQVSHLQAVYLSPEQHKEEMEALKSNGIELEKQLAELQRKYDDEQEKMCKLVSENTAIRESVKDQYVLAATHEEIKTALNNALEKSNKELSDLKEKNEERKQEFMRVDKENGALKDKVKLLQNQLQTQCVSLKEHDAKVTALNNSVRELQENNAAITAEYKRSQEEILQLHGEIEAQKKELDTIQECIKSKYAPVASFEDREQSFEATVKELKAQLQEQMRKCEESEEERRKCKEENGKLKKGIVSIQNDLQQNYVLAEKCHEMEKMFASKMEELNKQLREMLQKYTGKKDEKDELKESAKQGVAVQAPVGSQHLSVEQIDVLRSALGHTIEDLKEALRTKKECYDKETLRVGELQQELLDLKKSSVPLVEYTQMKEMLEQEILATKNSLKEKEGESQVKSEEILKLQAEIQRNQQALTDLESKEVVDLSEYNSMKSALEAQINTMAENLSSVNKKYEEACEEALQAKKSERSLQDEKELLQLRSCSIEQEIKDQKERCDKSLTTIIDLQKRIQESAKQVEAKDNKITELLNDVERLKQALNGLSQLTYTSGIPAKRQNQQVEMLQNQVKTLQQQLADAKRQHQEVVSVYRTHLLSAVQGHMDEDVQAALLQIIQMRQGLVC", "length": 1432, "header": "tr|A0A8V0Z5Q3-1|A0A8V0Z5Q3_CHICK Isoform 1 of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Gallus gallus OX=9031 GN=UACA PE=1 SV=1 CANONICAL=A0A8V0Z5Q3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3/entry#A0A8V0Z5Q3-1", "sequence": { "sequence": "MKARAAVCIPWEKKSVLHLHAVKWNHVLVCVMLVVAVKKHEESQEQQSVVQPALQCSPVQLNTDWNKYDDRLMKAAERGDVEKVSSILAKKGVSPTKLDVEGRSAFHVVASKGNLDCLNTILIHGVDITATDAAGRNALHLAAKYGHALCLQKLLQYNCPTENVDLQGRTALHDAAMSDCSSSIQLLCDHGASVNAKDGDGRTPLVLATQMCRPTVCQLLIDRGADVNARDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLVDGLGHDCAYYARIGDNIDILALIKAAVEDSSKARDTMKRGQPEQKMNNMSQKWNRLHAQEEVNVKLYQKEHNAQELELENQDLKDRMREVQEEQRMLLDRISGLQLQLTEKDELKKILTTKEKQQEESLRTIEALKAKLKYYEVDLVGSGSNFSNRKEDLLKQGQVFAVESQSRSMLRPLELSLPHQSPNSERETLKKELDNVRTCYGAAKEEISKLQRELSHKVSECKALASECERTKEESDGQIKQLEDALKDVQKRMFESEGKVKQMQTHFLALKDHLTNEAASGNSKLTEELKDQLKEMKTKYEGASAEVGKLRNQIKQNELLVAEFKRDEGRLVEENKRLQKELVKLEMERDKRERSVMELEGQLKETAAKLARSVTSEKFENMKSSLSNEVNEKARKLAEIEGESEKLQAEIWALKRECDSQKAKLAQHVKPEDHEQMRSGFEQKHEELEGRISELSQKNQTLQKELERFQTDNKMLKQQLQVLKTEIKSQNVPLKIHEELKKTSDVTVGDLTKKLLEITRKYNESQAEAERLLAEKNSLSEQVSHLQAVYLSPEQHKEEMEALKSNGIELEKQLAELQRKYDDEQEKMCKLVSENTAIRESVKDQYVLAATHEEIKTALNNALEKSNKELSDLKEKNEERKQEFMRVDKENGALKDKVKLLQNQLQTQCVSLKEHDAKVTALNNSVRELQENNAAITAEYKRSQEEILQLHGEIEAQKKELDTIQECIKSKYAPVASFEDREQSFEATVKELKAQLQEQMRKCEESEEERRKCKEENGKLKKGIVSIQNDLQQNYVLAEKCHEMEKMFASKMEELNKQLREMLQKYTGKKDEKDELKESAKQGVAVQAPVGSQHLSVEQIDVLRSALGHTIEDLKEALRTKKECYDKETLRVGELQQELLDLKKSSVPLVEYTQMKEMLEQEILATKNSLKEKEGESQVKSEEILKLQAEIQRNQQALTDLESKEVVDLSEYNSMKSALEAQINTMAENLSSVNKKYEEACEEALQAKKSERSLQDEKELLQLRSCSIEQEIKDQKERCDKSLTTIIDLQKRIQESAKQVEAKDNKITELLNDVERLKQALNGLSQLTYTSGIPAKRQNQQVEMLQNQVKTLQQQLADAKRQHQEVVSVYRTHLLSAVQGHMDEDVQAALLQIIQMRQGLVC", "length": 1432, "header": "tr|A0A8V0Z5Q3-1|A0A8V0Z5Q3_CHICK Isoform 1 of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Gallus gallus OX=9031 GN=UACA PE=1 SV=1 CANONICAL=A0A8V0Z5Q3-1" }, "locus": { "chromosome": "10", "start_pos": 19660521, "end_pos": 19637114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048471.1", "url": "https://www.ensembl.org/id/ENSGALT00010048471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028580.1", "url": "https://www.ensembl.org/id/ENSGALP00010028580.1" } ] } }, { "isoform_ac": "A0A8V0ZCE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3/entry#A0A8V0ZCE2-1", "sequence": { "sequence": "MEKISWYEVTGMAGSVEVKYNCPTENVDLQGRTALHDAAMSDCSSSIQLLCDHGASVNAKDGDGRTPLVLATQMCRPTVCQLLIDRGADVNARDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLVDGLGHDCAYYARIGDNIDILALIKAAVEDSSKARDTMKRGQPEQKMNNMSQKWNRLHAQEEVNVKLYQKEHNAQELELENQDLKDRMREVQEEQRMLLDRISGLQLQLTEEQMFADDLENEKDELKKILTTKEKQQEESLRTIEALKAKLKYYEVDLVGSGSNFSNRKEDLLKQGQVFAVESQSRSMLRPLELSLPHQSPNSERETLKKELDNVRTCYGAAKEEISKLQRELSHKVSECKALASECERTKEESDGQIKQLEDALKDVQKRMFESEGKVKQMQTHFLALKDHLTNEAASGNSKLTEELKDQLKEMKTKYEGASAEVGKLRNQIKQNELLVAEFKRDEGRLVEENKRLQKELVKLEMERDKRERSVMELEGQLKETAAKLARSVTSEKFENMKSSLSNEVNEKARKLAEIEGESEKLQAEIWALKRECDSQKAKLAQHVKPEDHEQMRSGFEQKHEELEGRISELSQKNQTLQKELERFQTDNKMLKQQLQVLKTEIKSQNVPLKIHEELKKTSDVTVGDLTKKLLEITRKYNESQAEAERLLAEKNSLSEQVSHLQAVYLSPEQHKEEMEALKSNGIELEKQLAELQRKYDDEQEKMCKLVSENTAIRESVKDQYVLAATHEEIKTALNNALEKSNKELSDLKEKNEERKQEFMRVDKENGALKDKVKLLQNQLQTQCVSLKEHDAKVTALNNSVRELQENNAAITAEYKRSQEEILQLHGEIEAQKKELDTIQECIKSKYAPVASFEDREQSFEATVKELKAQLQEQMRKCEESEEERRKCKEENGKLKKGIVSIQNDLQQNYVLAEKCHEMEKMFASKMEELNKQLREMLQKYTGKKDEKDELKESAKQGVAVQAPVGSQHLSVEQIDVLRSALGHTIEDLKEALRTKKECYDKETLRVGELQQELLDLKKSSVPLVEYTQMKEMLEQEILATKNSLKEKEGESQVKSEEILKLQAEIQRNQQALTDLESKEVVDLSEYNSMKSALEAQINTMAENLSSVNKKYEEACEEALQAKKSERSLQDEKELLQLRSCSIEQEIKDQKERCDKSLTTIIDLQKRIQESAKQVEAKDNKITELLNDVERLKQALNGLSQLTYTSGIPAKRQNQQVEMLQNQVKTLQQQLADAKRQHQEVVSVYRTHLLSAVQGHMDEDVQAALLQIIQMRQGLVC", "length": 1306, "header": "tr|A0A8V0ZCE2-1|A0A8V0ZCE2_CHICK Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Gallus gallus OX=9031 GN=UACA PE=1 SV=1 CANONICAL=A0A8V0Z5Q3-1" }, "locus": { "chromosome": "10", "start_pos": 19650543, "end_pos": 19637114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048453.1", "url": "https://www.ensembl.org/id/ENSGALT00010048453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028567.1", "url": "https://www.ensembl.org/id/ENSGALP00010028567.1" } ] } }, { "isoform_ac": "A0A8V0ZCZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3/entry#A0A8V0ZCZ0-1", "sequence": { "sequence": "MTCWFSCAAKDTLNTDWNKYDDRLMKAAERGDVEKVSSILAKKGVSPTKLDVEGRSAFHVVASKGNLDCLNTILIHGVDITATDAAGRNALHLAAKYGHALCLQKLLQYNCPTENVDLQGRTALHDAAMSDCSSSIQLLCDHGASVNAKDGDGRTPLVLATQMCRPTVCQLLIDRGADVNARDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLVDGLGHDCAYYARIGDNIDILALIKAAVEDSSKARDTMKRGQPEQKMNNMSQKWNRLHAQEEVNVKLYQKEHNAQELELENQDLKDRMREVQEEQRMLLDRISGLQLQLTEEQMFADDLENEKDELKKILTTKEKQQEESLRTIEALKAKLKYYEVDLVGSGSNFSNRKEDLLKQGQVFAVESQSRSMLRPLELSLPHQSPNSERETLKKELDNVRTCYGAAKEEISKLQRELSHKVSECKALASECERTKEESDGQIKQLEDALKDVQKRMFESEGKVKQMQTHFLALKDHLTNEAASGNSKLTEELKDQLKEMKTKYEGASAEVGKLRNQIKQNELLVAEFKRDEGRLVEENKRLQKELVKLEMERDKRERSVMELEGQLKETAAKLARSVTSEKFENMKSSLSNEVNEKARKLAEIEGESEKLQAEIWALKRECDSQKAKLAQHVKPEDHEQMRSGFEQKHEELEGRISELSQKNQTLQKELERFQTDNKMLKQQLQVLKTEIKSQNVPLKIHEELKKTSDVTVGDLTKKLLEITRKYNESQAEAERLLAEKNSLSEQVSHLQAVYLSPEQHKEEMEALKSNGIELEKQLAELQRKYDDEQEKMCKLVSENTAIRESVKDQYVLAATHEEIKTALNNALEKSNKELSDLKEKNEERKQEFMRVDKENGALKDKVKLLQNQLQTQCVSLKEHDAKVTALNNSVRELQENNAAITAEYKRSQEEILQLHGEIEAQKKELDTIQECIKSKYAPVASFEDREQSFEATVKELKAQLQEQMRKCEESEEERRKCKEENGKLKKGIVSIQNDLQQNYVLAEKCHEMEKMFASKMEELNKQLREMLQKYTGKKDEKDELKESAKQGVAVQAPVGSQHLSVEQIDVLRSALGHTIEDLKEALRTKKECYDKETLRVGELQQELLDLKKSSVPLVEYTQMKEMLEQEILATKNSLKEKEGESQVKSEEILKLQAEIQRNQQALTDLESKEVVDLSEYNSMKSALEAQINTMAENLSSVNKKYEEACEEALQAKKSERSLQDEKELLQLRSCSIEQEIKDQKERCDKSLTTIIDLQKRIQESAKQVEAKDNKITELLNDVERLKQALNGLSQLTYTSGIPAKRQNQQVEMLQNQVKTLQQQLADAKRQHQEVVSVYRTHLLSAVQGHMDEDVQAALLQIIQMRQGLVC", "length": 1395, "header": "tr|A0A8V0ZCZ0-1|A0A8V0ZCZ0_CHICK Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Gallus gallus OX=9031 GN=UACA PE=1 SV=1 CANONICAL=A0A8V0Z5Q3-1" }, "locus": { "chromosome": "10", "start_pos": 19654921, "end_pos": 19637114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048459.1", "url": "https://www.ensembl.org/id/ENSGALT00010048459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028571.1", "url": "https://www.ensembl.org/id/ENSGALP00010028571.1" } ] } }, { "isoform_ac": "A0A8V0ZD05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3/entry#A0A8V0ZD05-1", "sequence": { "sequence": "MKSLKSRLRKHEAIIAGSALNTDWNKYDDRLMKAAERGDVEKVSSILAKKGVSPTKLDVEGRSAFHVVASKGNLDCLNTILIHGVDITATDAAGRNALHLAAKYGHALCLQKLLQYNCPTENVDLQGRTALHDAAMSDCSSSIQLLCDHGASVNAKDGDGRTPLVLATQMCRPTVCQLLIDRGADVNARDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLVDGLGHDCAYYARIGDNIDILALIKAAVEDSSKARDTMKRGQPEQKMNNMSQKWNRLHAQEEVNVKLYQKEHNAQELELENQDLKDRMREVQEEQRMLLDRISGLQLQLTEEQMFADDLENEKDELKKILTTKEKQQEESLRTIEALKAKLKYYEVDLVGSGSNFSNRKEDLLKQGQVFAVESQSRSMLRPLELSLPHQSPNSERETLKKELDNVRTCYGAAKEEISKLQRELSHKVSECKALASECERTKEESDGQIKQLEDALKDVQKRMFESEGKVKQMQTHFLALKDHLTNEAASGNSKLTEELKDQLKEMKTKYEGASAEVGKLRNQIKQNELLVAEFKRDEGRLVEENKRLQKELVKLEMERDKRERSVMELEGQLKETAAKLARSVTSEKFENMKSSLSNEVNEKARKLAEIEGESEKLQAEIWALKRECDSQKAKLAQHVKPEDHEQMRSGFEQKHEELEGRISELSQKNQTLQKELERFQTDNKMLKQQLQVLKTEIKSQNVPLKIHEELKKTSDVTVGDLTKKLLEITRKYNESQAEAERLLAEKNSLSEQVSHLQAVYLSPEQHKEEMEALKSNGIELEKQLAELQRKYDDEQEKMCKLVSENTAIRESVKDQYVLAATHEEIKTALNNALEKSNKELSDLKEKNEERKQEFMRVDKENGALKDKVKLLQNQLQTQCVSLKEHDAKVTALNNSVRELQENNAAITAEYKRSQEEILQLHGEIEAQKKELDTIQECIKSKYAPVASFEDREQSFEATVKELKAQLQEQMRKCEESEEERRKCKEENGKLKKGIVSIQNDLQQNYVLAEKCHEMEKMFASKMEELNKQLREMLQKYTGKKDEKDELKESAKQGVAVQAPVGSQHLSVEQIDVLRSALGHTIEDLKEALRTKKECYDKETLRVGELQQELLDLKKSSVPLVEYTQMKEMLEQEILATKNSLKEKEGESQVKSEEILKLQAEIQRNQQALTDLESKEVVDLSEYNSMKSALEAQINTMAENLSSVNKKYEEACEEALQAKKSERSLQDEKELLQLRSCSIEQEIKDQKERCDKSLTTIIDLQKRIQESAKQVEAKDNKITELLNDVERLKQALNGLSQLTYTSGIPAKRQNQQVEMLQNQVKTLQQQLADAKRQHQEVVSVYRTHLLSAVQGHMDEDVQAALLQIIQMRQGLVC", "length": 1402, "header": "tr|A0A8V0ZD05-1|A0A8V0ZD05_CHICK Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Gallus gallus OX=9031 GN=UACA PE=1 SV=1 CANONICAL=A0A8V0Z5Q3-1" }, "locus": { "chromosome": "10", "start_pos": 19663858, "end_pos": 19637114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048485.1", "url": "https://www.ensembl.org/id/ENSGALT00010048485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028589.1", "url": "https://www.ensembl.org/id/ENSGALP00010028589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415569", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415569", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZGS5-1", "protein_name": "Uveal autoantigen with coiled-coil domains and ankyrin repeats", "gene_name": "Uaca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSLKSRLWRQDAPGPTSPTSPTAVTSSLSAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTASESTSKGRELWRKGPPLQQRNLSHTQDEGNVKSNQREHHSFQDLEMENEDLKEKLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHPGPGSYSSNRKEDMLHKQGQMYTADSQCTSPGVPPHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1408 }, "evidence": [ { "id": "A0A8V0Z5Q3", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Q3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CGB3-1", "protein_name": "Uveal autoantigen with coiled-coil domains and ankyrin repeats", "gene_name": "Uaca", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSLKSRLWKQDAPGPTSPSSPTAVASTQSAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAVMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKNGADLTLLDALGHDSSYYARIGDNLDILNLLKTASENTNKGRELWRKGPPLQQRNLSHTQDEGSVKSTQREQREPHSFQDLEIENEDLREKLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKPKSLLAAKEKQHEESLRTIEALKNRFKYFESDHPGPGSYPSNRKEDMLHKQGQMYTTEPQCASPGIPPHMHSRSMLRPLELSLPSQTSYSENEILKKELETLRTYYDSAKQDRLKFQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATGSHRIIEELREQLKDLKGKYEGASAEVGKLRSQIKQSEMLVGEFKRDEGRLVEENKRLQKECGTCEVELERRGRRVVELEGQLKELGAKLALSVPTEKFESMKSSLSNDINEKVKRLAEVGRDYESAQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVSELTLKNQTLQKDVEKLHADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKRSHDVNVEDLNKKLSEATQRYAEKKQEAERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKKQLSELNKKCGEGQEKIRALMSENSSLKKTLSSQYVPAKTHEEVKASLNSTVEKTNRALLEAKKRFDDTSQEVSKLRDENEVLRRNLENVQNQMKADYVSLEEHSRRMSTVSQSLKEAQEANAAILADHRQGQEEIVSLHAEIKAQKKELDTIQECIKLKYAPLARLEECERKFKATEKGLKEQLSEQTHKCRQRDEEVKKGKQENERLRADLAALQKELQDRNALAEEAREAERALSGKADELSKQLKDLSQKYSDVKSEREKLVEEKAKQASEILAAQNLLQKQPVPLEQVEALKKSLNGTIEQLKEELRSKQRCLEREQQTVSQLQQLLENQKNSSVTLAEHLKLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQTTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQACEEKVSAKDEKELLHLSIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGSPTKRQSQLVDTLQQRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1411 }, "evidence": [ { "id": "A0A8V0Z5Q3", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Q3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZF9-1", "protein_name": "Uveal autoantigen with coiled-coil domains and ankyrin repeats", "gene_name": "UACA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC", "length": 1416 }, "evidence": [ { "id": "A0A8V0Z5Q3", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Q3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Q3", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5R4-1", "uniprot_ac": "A0A8V0Z5R4", "uniprot_id": "A0A8V0Z5R4_CHICK", "mass": { "chemical_mass": 35091.0, "monoisotopic_mass": 35091.0 }, "refseq": { "ac": "NP_990362", "name": "homeobox protein Nkx-2.3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" }, "gene_names": [ { "name": "NKX2-3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ] }, { "name": "CNKX-2.3", "type": "synonym", "evidence": [ { "id": "NP_990362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" } ] }, { "name": "NKX2-3", "type": "synonym", "evidence": [ { "id": "NP_990362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" } ] } ], "protein_names": [ { "name": "NK2 homeobox 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4/entry#names_and_taxonomy" } ] }, { "name": "NK2 transcription factor related, locus 3", "type": "synonym", "evidence": [ { "id": "NP_990362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" } ] }, { "name": "homeobox protein Nkx-2.3", "type": "synonym", "evidence": [ { "id": "NP_990362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X97667.1, SRR12888522.137250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Sep 23, 2021 this sequence version replaced NP_990362.2.", "evidence": [ { "database": "RefSeq", "id": "NP_990362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NKX2-3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4", "locus": { "chromosome": "25", "start_pos": 1658945, "end_pos": 1655155, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028216", "url": "https://www.ensembl.org/id/ENSGALG00010028216" } ] } } ], "crossref": [ { "id": "A0A8V0Z5R4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107053698", "url": "https://www.ncbi.nlm.nih.gov/gene/107053698", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107053698", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053698", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKSCPLK", "url": "https://omabrowser.org/oma/group/QKSCPLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5R4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLPSPVTSTPFSVKDILNLEQQQQDPHYGAQLPHHLEHHFHPAACLLAAADGTRFSDGEEEEEEEKLSYLSSVATPGGQADARLSADSYVHAVLRGSCEAPGPGEELDPTARDPKSCALKKPLDAAEKPEEAERPKQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGGPAAPPPPRRVAVPVLVRDGKPCLGGSQGYSSAYNGPYSYNGFPAYGYGNAASYNPGYGCTYPAGSGGASVQAACSPAAAAGPFVNVGGLGGFGGGGQALHQAAAGPSCSQGALQGIRAW", "length": 328, "header": "tr|A0A8V0Z5R4-1|A0A8V0Z5R4_CHICK Isoform 1 of NK2 homeobox 3 OS=Gallus gallus OX=9031 GN=NKX2-3 PE=3 SV=1 CANONICAL=A0A8V0Z5R4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4/entry#A0A8V0Z5R4-1", "sequence": { "sequence": "MMLPSPVTSTPFSVKDILNLEQQQQDPHYGAQLPHHLEHHFHPAACLLAAADGTRFSDGEEEEEEEKLSYLSSVATPGGQADARLSADSYVHAVLRGSCEAPGPGEELDPTARDPKSCALKKPLDAAEKPEEAERPKQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGGPAAPPPPRRVAVPVLVRDGKPCLGGSQGYSSAYNGPYSYNGFPAYGYGNAASYNPGYGCTYPAGSGGASVQAACSPAAAAGPFVNVGGLGGFGGGGQALHQAAAGPSCSQGALQGIRAW", "length": 328, "header": "tr|A0A8V0Z5R4-1|A0A8V0Z5R4_CHICK Isoform 1 of NK2 homeobox 3 OS=Gallus gallus OX=9031 GN=NKX2-3 PE=3 SV=1 CANONICAL=A0A8V0Z5R4-1" }, "locus": { "chromosome": "6", "start_pos": 22912851, "end_pos": 22911309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044176.1", "url": "https://www.ensembl.org/id/ENSGALT00010044176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026271.1", "url": "https://www.ensembl.org/id/ENSGALP00010026271.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107053698", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053698", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZC9-1", "protein_name": "NK2 homeobox 3", "gene_name": "Nkx2-3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMIPSPVTSTPFSVKDILNLEQQRHFHGAHLQAELEQHLHSAPCMLAAAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGVSGLCPQSYVHTVLRDSCSGPKEQEEEVVSERSQKSCQLKKSLEAAGDCKASEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGAASAATTAMQPACSATGGGSFVNVGNLGGFGSGGGAQPLHQGAAAGAACAQGTLQGIRAW", "length": 362 }, "evidence": [ { "id": "A0A8V0Z5R4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5R4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S8W5-1", "protein_name": "NK2 homeobox 3", "gene_name": "NKX2-3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMLPSPVTSTPFSVKDILNLEHQQQQHFHGAHLQADLEHHFHSAPCTLATADGTQFSDGGEEDEEEEGEKLSYLNSLATADGHGDSGLCPQSYVHTVLRDACSGPKEHEEEPEVVRDRSQKSCQLKKTLEAAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGGHAPPPPPRRVAVPVLVRDGKPCVTPGAPAYGAPYSVGTGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPAGGGGGGGASAAASAMQPACSAAGGGPFVNMSNLGGFGGGGGGGGAQPLHQGAAAGAACAQGSLQGIRAW", "length": 367 }, "evidence": [ { "id": "A0A8V0Z5R4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5R4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97334-1", "protein_name": "Homeobox protein Nkx-2.3", "gene_name": "Nkx2-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLPSPVTSTPFSVKDILNLEQQRHFHGAHLQAELEQHFHSAPCMLATAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGDSGLCPQSYVHTVLRDACSGPKEQEEEVVSERSQKSCQLKKSLEAAGDCKTSEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGTASAATTAMQPACSATGGGSFVNVSNLGGFGSGGGAQPLHQGAAAGSACTQGTLQGIRAW", "length": 362 }, "evidence": [ { "id": "A0A8V0Z5R4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5R4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAU0-1", "protein_name": "Homeobox protein Nkx-2.3", "gene_name": "NKX2-3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAACAQGTLQGIRAW", "length": 364 }, "evidence": [ { "id": "A0A8V0Z5R4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5R4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R4" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 199, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 76 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139306.1. 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"url": "https://www.ncbi.nlm.nih.gov/gene/100858021", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DHEIKAM", "url": "https://omabrowser.org/oma/group/DHEIKAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5T6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF06699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEAELRRLLAANLLCAGSIVLTALVPALFLDGFSVLGTHLTWLCICSVCVSVLNVTLCLILKPSPSSKRSSLSNKISRFLKCCIYFFMSCILFHAIIVLYGAPLIESVTETFLFAVLLSTFTTLQCLCLLGPNIQAWIRVFSRNGAMSIWENSLQITTTCSILGGWFGAFPIPLDWDRPWQVWPISCSLGATFGYMAGLIIAPLWIHWNRKQLTYKSR", "length": 219, "header": "tr|A0A8V0Z5T6-1|A0A8V0Z5T6_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class F OS=Gallus gallus OX=9031 GN=PIGF PE=4 SV=1 CANONICAL=A0A8V0Z5T6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6/entry#A0A8V0Z5T6-1", "sequence": { "sequence": "MKEAELRRLLAANLLCAGSIVLTALVPALFLDGFSVLGTHLTWLCICSVCVSVLNVTLCLILKPSPSSKRSSLSNKISRFLKCCIYFFMSCILFHAIIVLYGAPLIESVTETFLFAVLLSTFTTLQCLCLLGPNIQAWIRVFSRNGAMSIWENSLQITTTCSILGGWFGAFPIPLDWDRPWQVWPISCSLGATFGYMAGLIIAPLWIHWNRKQLTYKSR", "length": 219, "header": "tr|A0A8V0Z5T6-1|A0A8V0Z5T6_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class F OS=Gallus gallus OX=9031 GN=PIGF PE=4 SV=1 CANONICAL=A0A8V0Z5T6-1" }, "locus": { "chromosome": "3", "start_pos": 26446695, "end_pos": 26428243, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044523.1", "url": "https://www.ensembl.org/id/ENSGALT00010044523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026503.1", "url": "https://www.ensembl.org/id/ENSGALP00010026503.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZK79-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class F", "gene_name": "Pigf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDTDIKRLLYTNLLCIFSVFLSIFIPSFFLDNFSILETHLVWLGTCSAFVTGANLLLYLVVKPNVSSKRSSLSHKVARVVRCWLYFLASCFFLHIIFVLYGAPLMELVLETFLFAVVLSTFTTVPCLCLLGPNLKAWLRVFSRNGVTSVWENSLQITTVSSFIGAWLGAFPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN", "length": 219 }, "evidence": [ { "id": "A0A8V0Z5T6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7JPG0-1", "protein_name": "Phosphatidylinositol-glycan biosynthesis class F protein isoform X1", "gene_name": "Pigf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKDTDIKRLLYSNLLCIFSVFLSIFIPSLFLDNFSILETHLTWLCTCSASVTGVNLLLHLVVKPNVSSRRSSLSHKVTRVLKCCIYFLLSCFFLHIIFVLYGAPLIELVLETFLFAVILSTFTTIPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFIGAWLGAFPIPLDWERPWQFLWCHCYSPINQILQIKTSLWLIMLIESARKADKGMMGLAKCGDFARANFEKILLYKLCSLKYSTLLKDFSSPFLATHYTLDMFTLCSKQASLGYVLFIFWRNGSVWFL", "length": 291 }, "evidence": [ { "id": "A0A8V0Z5T6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1S5M1-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis class F", "gene_name": "PIGF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDTDIKRLLYAHLLCIFSIILSIFIPSFFLENFSILETHLTWLCICSVFVTAVNLILYLVVKSNTSSKRSSLSYKVTRFLKCCIYLLLSCFSFHVVFVLYGAPLIELVLETFLLAVILSTFTTVPCLCLLGPNFKAWLRVFSRNGVTSIWENSLQITTISSFIGTWLGAFPIPLDWGRPWQEWPISCTLGATFGYVAGLVISPLWIYWNRKKLTYKSN", "length": 219 }, "evidence": [ { "id": "A0A8V0Z5T6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O09101-1", "protein_name": "GPI ethanolamine phosphate transferase, stabilizing subunit", "gene_name": "Pigf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDTDIKRLLYTNLLCVFSIFLSIFIPSFFVDNFSVLEAHLTWLCICSASVTTVNLLSYLVVKPNVSSKRSSLSHKVTRALKCCVCFLMSCFLLHIIFVLYGAPLIELVLETFLFAVVLSTFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFTGAWLGAFPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN", "length": 219 }, "evidence": [ { "id": "A0A8V0Z5T6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q07326-1", "protein_name": "GPI ethanolamine phosphate transferase, stabilizing subunit", "gene_name": "PIGF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDNDIKRLLYTHLLCIFSIILSVFIPSLFLENFSILETHLTWLCICSGFVTAVNLVLYLVVKPNTSSKRSSLSHKVTGFLKCCIYFLMSCFSFHVIFVLYGAPLIELALETFLFAVILSTFTTVPCLCLLGPNLKAWLRVFSRNGVTSIWENSLQITTISSFVGAWLGALPIPLDWERPWQVWPISCTLGATFGYVAGLVISPLWIYWNRKQLTYKNN", "length": 219 }, "evidence": [ { "id": "A0A8V0Z5T6", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5T7-1", "uniprot_ac": "A0A8V0Z5T7", "uniprot_id": "A0A8V0Z5T7_CHICK", "mass": { "chemical_mass": 79075.0, "monoisotopic_mass": 79075.0 }, "refseq": {}, "gene_names": [ { "name": "IQCE", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ] } ], "protein_names": [ { "name": "IQ motif containing E", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IQCE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "416473", "url": "https://www.ncbi.nlm.nih.gov/gene/416473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5T7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCH8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ35", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5635838", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5635838", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGGGEAAAEGELGDDSLSVITCESDAEMKLKKKIFHKPPKSPKSPYSSSTQLYPKKAAVWRSLQGTGNVHFESAAMKNPKQMWLGSLKQGMSHSLKSDVDMGHTRAGISSSTPDYLKEALGMKKPKHSRSSSNGKLYGYIPGTPDYKEKEDMYDEIIELKKTIQAQKNEGNRMKTKLRRLEEENNRKDKQIEQLLDPSRGSELARSLSAKMADNGWVVSGLKQKIFKLEQQCKEKDNTINKFQSDMKTTDLEEMRIAMETYCEEVHRLQILLAKSETMKKNAEGRDTQKRLKALNAAVLRLSRNIKELQAENRCLKEDLDHILSCSPASSKKKNYSEWSRQSLMRRILELEKKVGDMENTRVQSADSESAQLLGVSTSPSTDPNCAASQQVDHIEECHRLRGLVKKLKSDRSALQSLLLNKELDIKQLLRAKAEAELELQKYQNNKEESTKEEQTLSEEIQNLTEKVGKSQSKLEEEERQMTEDALKKLNKCSPVCTVKDEDDCKKEQAAKCIQRWWRLYRNKKEEIALDEAVVVLQAAFRGHLARQKLLLSSGLHDAQSYNRQNLGRKNSCVPHVSNSLSSSSLCKEKEKTVTFIQSVFRAHLTRAVQLEERSSMSSATSEKTDSAICITENKPVSAALQRTSTSISSLPVLLAGSCEKQPQSTLSVPVDEAHSDDSDDIVIVSPSLRMKKTSTHFFNGL", "length": 703, "header": "tr|A0A8V0Z5T7-1|A0A8V0Z5T7_CHICK Isoform 1 of IQ motif containing E OS=Gallus gallus OX=9031 GN=IQCE PE=4 SV=1 CANONICAL=A0A8V0Z5T7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7/entry#A0A8V0Z5T7-1", "sequence": { "sequence": "MARGGGEAAAEGELGDDSLSVITCESDAEMKLKKKIFHKPPKSPKSPYSSSTQLYPKKAAVWRSLQGTGNVHFESAAMKNPKQMWLGSLKQGMSHSLKSDVDMGHTRAGISSSTPDYLKEALGMKKPKHSRSSSNGKLYGYIPGTPDYKEKEDMYDEIIELKKTIQAQKNEGNRMKTKLRRLEEENNRKDKQIEQLLDPSRGSELARSLSAKMADNGWVVSGLKQKIFKLEQQCKEKDNTINKFQSDMKTTDLEEMRIAMETYCEEVHRLQILLAKSETMKKNAEGRDTQKRLKALNAAVLRLSRNIKELQAENRCLKEDLDHILSCSPASSKKKNYSEWSRQSLMRRILELEKKVGDMENTRVQSADSESAQLLGVSTSPSTDPNCAASQQVDHIEECHRLRGLVKKLKSDRSALQSLLLNKELDIKQLLRAKAEAELELQKYQNNKEESTKEEQTLSEEIQNLTEKVGKSQSKLEEEERQMTEDALKKLNKCSPVCTVKDEDDCKKEQAAKCIQRWWRLYRNKKEEIALDEAVVVLQAAFRGHLARQKLLLSSGLHDAQSYNRQNLGRKNSCVPHVSNSLSSSSLCKEKEKTVTFIQSVFRAHLTRAVQLEERSSMSSATSEKTDSAICITENKPVSAALQRTSTSISSLPVLLAGSCEKQPQSTLSVPVDEAHSDDSDDIVIVSPSLRMKKTSTHFFNGL", "length": 703, "header": "tr|A0A8V0Z5T7-1|A0A8V0Z5T7_CHICK Isoform 1 of IQ motif containing E OS=Gallus gallus OX=9031 GN=IQCE PE=4 SV=1 CANONICAL=A0A8V0Z5T7-1" }, "locus": { "chromosome": "14", "start_pos": 3343375, "end_pos": 3321922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048525.1", "url": "https://www.ensembl.org/id/ENSGALT00010048525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028617.1", "url": "https://www.ensembl.org/id/ENSGALP00010028617.1" } ] } }, { "isoform_ac": "A0A8V0ZCH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7/entry#A0A8V0ZCH8-1", "sequence": { "sequence": "MARGGGEAAAEGELKLKKKIFHKPPKSPKSPYSSSTQLYPKKAAVWRSLQGTGNVHFESAAMKNPKQMWLGSLKQGMSHSLKSDVDMGHTRAGISSSTPDYLKEALGMKKPKHSRSSSNGYIPGTPDYKEKEDMYDEIIELKKTIQAQKNEGNRMKTKLRRLEEENNRKDKQIEQLLDPSRGSELARSLSAKMADNGWVVSGLKQKIFKLEQQCKEKDNTINKFQSDMKTTDLEEMRIAMETYCEEVHRLQILLAKSETMKKNAEGRDTQKRLKALNAAVLRLSRNIKELQAENRCLKEDLDHILSCSPASSKKKNYSEWSRQSLMRRILELEKKVGDMENTRVQSADSESAQLLGVSTSPSTDPNCAASQQVDHIEECHRLRGLVKKLKSDRSALQSLLLNKELDIKQLLRAKAEAELELQKYQNNKEESTKEEQTLSEEIQNLTEKVGKSQSKLEEEERQMTEDALKKLNKCSPVCTVKDEDDCKKEQAAKCIQRWWRLYRNKKEEIALDEAVVVLQAAFRGHLARQKLLLSSGLHDAQSYNRQNLGRKNSCVPHVSNSLSSSSLCKEKEKTVTFIQSVFRAHLTRAVQLEERSSMSSATSEKTDSAICITENKPVSAALQRTSTSISSLPVLLAGSCEKQPQSTLSVPVDEAHSDDSDDIVIVSPSLRMKKTSTHFFNGL", "length": 683, "header": "tr|A0A8V0ZCH8-1|A0A8V0ZCH8_CHICK Computationally mapped isoform of IQ motif containing E OS=Gallus gallus OX=9031 GN=IQCE PE=4 SV=1 CANONICAL=A0A8V0Z5T7-1" }, "locus": { "chromosome": "14", "start_pos": 3343375, "end_pos": 3321922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048520.1", "url": "https://www.ensembl.org/id/ENSGALT00010048520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028611.1", "url": "https://www.ensembl.org/id/ENSGALP00010028611.1" } ] } }, { "isoform_ac": "A0A8V0ZJ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7/entry#A0A8V0ZJ35-1", "sequence": { "sequence": "MCSRLRSRRFCQLSGDDSLSVITCESDAEMKLKKKIFHKPPKSPKSPYSSSTQLYPKKAAVWRSLQGTGNVHFESAAMKNPKQMWLGSLKQGMSHSLKSDVDMGHTRAGISSSTPDYLKEALGMKKPKHSRSSSNGYIPGTPDYKEKEDMYDEIIELKKTIQAQKNEGNRMKTKLRRLEEENNRKDKQIEQLLDPSRGSELARSLSAKMADNGWVVSGLKQKIFKLEQQCKEKDNTINKFQSDMKTTDLEEMRIAMETYCEEVHRLQILLAKSETMKKNAEGRDTQKRLKALNAAVLRLSRNIKELQAENRCLKEDLDHILSCSPASSKKKNYSEWSRQSLMRRILELEKKVGDMENTRVQSADSESAQLLGVSTSPSTDPNCAASQQVDHIEECHRLRGLVKKLKSDRSALQSLLLNKELDIKQLLRAKAEAELELQKYQNNKEESTKEEQTLSEEIQNLTEKVGKSQSKLEEEERQMTEDALKKLNKCSPVCTVKDEDDCKKEQAAKCIQRWWRLYRNKKEEIALDEAVVVLQAAFRGHLARQKLLLSSGLHDAQSYNRQNLGRKNSCVPHVSNSLSSSSLCKEKEKTVTFIQSVFRAHLTRAVQLEERSSMSSATSEKTDSAICITENKPVSAALQRTSTSISSLPVLLAGSCEKQPQSTLSVPVDEAHSDDSDDIVIVSPSLRMKKTSTHFFNGL", "length": 699, "header": "tr|A0A8V0ZJ35-1|A0A8V0ZJ35_CHICK Computationally mapped isoform of IQ motif containing E OS=Gallus gallus OX=9031 GN=IQCE PE=4 SV=1 CANONICAL=A0A8V0Z5T7-1" }, "locus": { "chromosome": "14", "start_pos": 3342572, "end_pos": 3321922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048517.1", "url": "https://www.ensembl.org/id/ENSGALT00010048517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028608.1", "url": "https://www.ensembl.org/id/ENSGALP00010028608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5635838", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5635838", "resource": "Reactome", "description": "Activation of SMO" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" }, { "name": "regulation of smoothened signaling pathway", "id": "GO:0008589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" }, { "name": "protein localization to motile cilium", "id": "GO:0120229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" }, { "name": "plasma membrane protein complex", "id": "GO:0098797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098797", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5T8-1", "uniprot_ac": "A0A8V0Z5T8", "uniprot_id": "A0A8V0Z5T8_CHICK", "mass": { "chemical_mass": 131738.0, "monoisotopic_mass": 131738.0 }, "refseq": { "ac": "XP_046756697", "name": "exportin-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756697" }, "gene_names": [ { "name": "XPO6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ] }, { "name": "XPO6", "type": "synonym", "evidence": [ { "id": "XP_046756697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756697" } ] } ], "protein_names": [ { "name": "Exportin 6", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8/entry#names_and_taxonomy" } ] }, { "name": "exportin-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046756697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756697" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XPO6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8", "locus": { "chromosome": "14", "start_pos": 13010131, "end_pos": 12967469, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018022", "url": "https://www.ensembl.org/id/ENSGALG00010018022" } ] } } ], "crossref": [ { "id": "A0A8V0Z5T8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "416410", "url": "https://www.ncbi.nlm.nih.gov/gene/416410", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KITRFNH", "url": "https://omabrowser.org/oma/group/KITRFNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5T8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21452:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21452:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046756697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPWSDSKERGSRCSQQPMICAVRAEASEEASLRALESLMTEFFHNCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAQHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILESIWDKHSVTAATPPPSPTSGESGDLLSSLLQSPSAAKLLNQPIPILDTDSEYICSLALECLAHLFSWIPLSTSITPSLLTTIFHFARFGCDTRVRKMSSVNGSSQNVGLGAERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKENNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLALLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLADKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGTGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDMFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQFYSEVHRQNPEQFISLVSTALEAITPLISSKVQEKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDTSAQRLPDKAQVLVCRALSNVLLLPWPNLPESEQQWAVRSTNHTSLISALTRDYRQLKSNAILPQRKVQLEDTKVIIHQTLSVLEDIVESISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFQGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSVISLCMEQVYPIIAERSSPDVKAELFELLFRVLHHNWRYFFKSSVLASVQRGVAEEQMENEAQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVLLQVLVHKSHDLLQEEIGIATYNMASVDFDGFYSAFLPEFLASCDGVDSNQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1151, "header": "tr|A0A8V0Z5T8-1|A0A8V0Z5T8_CHICK Isoform 1 of Exportin 6 OS=Gallus gallus OX=9031 GN=XPO6 PE=3 SV=1 CANONICAL=A0A8V0Z5T8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8/entry#A0A8V0Z5T8-1", "sequence": { "sequence": "MAVPWSDSKERGSRCSQQPMICAVRAEASEEASLRALESLMTEFFHNCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAQHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILESIWDKHSVTAATPPPSPTSGESGDLLSSLLQSPSAAKLLNQPIPILDTDSEYICSLALECLAHLFSWIPLSTSITPSLLTTIFHFARFGCDTRVRKMSSVNGSSQNVGLGAERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKENNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLALLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLADKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGTGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDMFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQFYSEVHRQNPEQFISLVSTALEAITPLISSKVQEKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDTSAQRLPDKAQVLVCRALSNVLLLPWPNLPESEQQWAVRSTNHTSLISALTRDYRQLKSNAILPQRKVQLEDTKVIIHQTLSVLEDIVESISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFQGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSVISLCMEQVYPIIAERSSPDVKAELFELLFRVLHHNWRYFFKSSVLASVQRGVAEEQMENEAQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVLLQVLVHKSHDLLQEEIGIATYNMASVDFDGFYSAFLPEFLASCDGVDSNQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1151, "header": "tr|A0A8V0Z5T8-1|A0A8V0Z5T8_CHICK Isoform 1 of Exportin 6 OS=Gallus gallus OX=9031 GN=XPO6 PE=3 SV=1 CANONICAL=A0A8V0Z5T8-1" }, "locus": { "chromosome": "14", "start_pos": 13009522, "end_pos": 12967698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043559.1", "url": "https://www.ensembl.org/id/ENSGALT00010043559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025908.1", "url": "https://www.ensembl.org/id/ENSGALP00010025908.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 236, "start_aa": "Thr", "end_pos": 236, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr236", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MI29-1", "protein_name": "Exportin-6", "gene_name": "XPO6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDAESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGPRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFTGDVFAARFSDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEAHRQNTQQFVSLISTTMDAITPLITTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASAQRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSMNHASLISALSRDYRNLKPNAVTPQRKMPLDDTKVIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTILASVQRGMAEEQMENQPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRSAMLFQFVNVLLQVLVCRSHDLLQEDIGIAIYNMASVDFDGFFTAFLPEFLTSCDGVDANQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1125 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RFG5-1", "protein_name": "Exportin-6", "gene_name": "XPO6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFSDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEAHRQNTQQFVSLISTTMDAVTPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFSRITDASAQRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPNAVAPQRKMPLDDTKVIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIISLCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1125 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V858-1", "protein_name": "Exportin-6", "gene_name": "Xpo6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEDASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQVGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLHQPIPILDVESEYVCSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDTRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYVEKFTDFLRLFVSVHLRRIESYSQFPVLEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFTGDVFAARFSDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEAHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAMQKVFNSIIDASAQRLTDKAQVLVCRALSNTLLLPWPNLPESEQQWPLRSINHASLISALSRDYHSLKPSAAAPQRKMPLDDTKVIIHQTLSVFEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1125 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54CB2-1", "protein_name": "Exportin-6", "gene_name": "xpo6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNDMDQKAKELQNVLEQFYLTTDNPKRKEIDTILNNYKAQSDSYEHVQYYLVHSDNQYVIWFSLSVIEDKVNKAWNSISASSQTQTKGLLLDIYLNKTGANSNSTVKNVLPQFIISKLGQVIADIGRYEFESNPQSYLLNITSIVRNPSTSIRGINLLQCISDSFTTNKKVISQQKKTTLKKLLHQNSPIIIQVLVDCLGQLFDQNAEKKFKHANLLAFHVGSPDTNTYTASFNAESKNLTKAVFDALLSYFTWVPLSDLLVPSLFDILFKYLRLDKNSIPALECLNEIVSKNLVPKGFESFLMRIFHQVYSLLTDIVSNGGQQINQYHPEFLNKFTQFIQIFINNHLGRIETNPNFPIPDFLGLLFQYSFFQTQPESFLQCIDIWSTFLDYLINLSQENGTPPPSKYTDGLLLFQSELVKRILYIFNNNTLSELDDEDKEINENGISETQLESYIKKSIEVVAKVTELYPEKSLENLYPLFTQNVTSFFCKAEESIKQGVSMENEQQFQYLVKDVTTILHLFGRLADQFVVSFAQTFTAANFIFQKLLDMCLFSVNQYIYKFGSDWEKLQIELLCTIRSFCFWLAEYGNQVRAIVGQQPDFDSNITKLISIIVPLFERNAPESILSSAGKLLMSLATISKPLNLFTQMDMLISNIHNICAPLSPSIQSILYPAISCTILLPPSNVNLSQQWDQRRPKYSPFIKGITASFLEIPQIPNFVEGKIFCKEELIQRVLRVLKVVTAIIRTVPEVTQAKSILHDGIQDTLKVTLGLFRVYISYPIVLEAILDFFFVLFEFLKAQVGVVFTQQTISTFLDILGGDNLNQLLSSGNDTGISIIKKLIEILTFIVQQPGNSFESLLGSTIEFSMEKLYPMIANTSSVLRSPFFTLLYSILDNHWKQCQQIQINSILTSFQSIFKQNDVNLFKQNLDHFEKLNSKLKLYEKISSMEPVFGCSFISMFFDVLISDTQSVHTDDIIVTIYRFASLNFDKFFNEFFTTFLVQKNQLSNEQKQILRSNFSNAIDQPTFSTNMTQFINDFSYFSFINS", "length": 1047 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q924Z6-1", "protein_name": "Exportin-6", "gene_name": "Xpo6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQVGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLHQPIPILDVESEYVCSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDTRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCGEAHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNSIIDASAQRLTDKAQVLVCRALSNTLLLPWPNLPESEQQWPLRSINHASLISALSRDYHSLKPSATAPQRKVPLGDTKVIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1125 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QU8-1", "protein_name": "Exportin-6", "gene_name": "XPO6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL", "length": 1125 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X2J9Y4-1", "protein_name": "Ellipsoid body open, isoform C", "gene_name": "ebo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHAASLTTVEGLLQEFYQPSTSNARKREIETNLLAFKSQPEAWQLCLRVATSSDTTENQFLWFFSTSTLEHTITRRWTQLTSTDKTLLRETLWNSYAQLVATPNVAKRHRDTLAQLIALLGKREFPEQDPNYMQHCMELTKTRFQLGINLLKITSEEVVSNRGDLTTEWKQYFYSCISMCVPDVLDLVTKYLLIAVCHINGKDIQTTIPNTLMDFSLTSALPNDNQLSSSILDLLGCVQHLVSWIRTELISEYFLMSILDLSQWRPAHEPISLAALSVLNELLYLQKPLPFPGPLMGGVTSLLEQHNNNRRQSEMYSDKFRELLRLYTTKYAAKLMQEPDLLETFLNLLYSCTTELHGALDFTEKLEIWTPIIKGIAQHPAKITRYNNVLTQLVDEIMRRTQFEANKPELEVLDNELMEDDTSATEWQQFLDQCFESLALLANTRGAHIVFAQVYNHWSRPQMYLLSLEHALDHGSARSYEAARKLKGANVGEILRDFATVCQAVVRLAPLMDSSTAAPGVADEMECQLQMLSDSLLQTLQLLASNRLYSGGSEMDKATFQTDLDNLYAQVLLAMRSIFPLTKAMSGEELLHRLFAILGSIFACNGSLTAASPIVQQAASELLLFISTVIRPKCLLDIPQIQSLLQAGSRLGAQLPRQVCINVHISLVSYMVLPWKSVPEQQQEYPRRLWMLREYVQGLAQNFLDLDLGQANESKVAATTLSLLGTFTALIEYFKATGGNAKDMLASTFKPILTKALMIFNNFGQSSIAMAITVAEFSLSMLRTLPTHLGAQFIKEMITLFISVSSREQLTLSRLAVMEKILQMFKLIVEQPGSASLGLLPSILDFSTQQILPLLQQQNAATDNSEITSLLYALFDSVLTCKWQFFYKNQLSNGHSGGGSGNFNCSDNLHPAHFMAILNAYGQMLVSGTDPSNVRSVLFSMQNVNERSRLYQRALFKEQLLASFQRALLNLLLSGEGSLHFDMIAQALYAMGQVDRRQLLESFVHASLPVAQTSLEEICQTNVLPFIVQDIPTFTQKLTQLMQDAHCVHLNETA", "length": 1054 }, "evidence": [ { "id": "A0A8V0Z5T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z5T8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T8" }, { "id": "PS50166", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 123, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 236 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 776, "end_pos": 778 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5U7-1", "uniprot_ac": "A0A8V0Z5U7", "uniprot_id": "A0A8V0Z5U7_CHICK", "mass": { "chemical_mass": 71233.0, "monoisotopic_mass": 71233.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CTNA1 protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5U7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5U7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18914:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18914:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPFYLYDLGIQIENKAIQRILCPMATELCHLILALEQEDGMRQTLPNIEENAEKLAKATDELASAARRLAEQSGDKVYQEETHLTAESLVLAGRHVLQAARQLQGKPDSPTHREALAAAAKGVLTETVKILQIEGAAGARRIMQAASWLLECLGTLRDTRDMPGLLAAFQDFSKALLLLSNLTAKHLEELQDSPRRTSLAQTLQLLQKCIPLLHESKHSHLKCSWAQQVNFSKNYAFQLMERTIQELVSLLVNSTGSKELQDRHGTFSHHVHRLLALLSHPEPVHLSDSEFSAHVEAVVFYCMLLAEMCRADLKKDLVKHCWVLLRLRKSICCHISQEGRTRPSWGENSLREKCHSMGKEVEDLDQAVLKATLHKILDTFSEAKEPLRQLVEEALTLAGTGCFLAGQGGLLKKLQPLTATFFAQAQQMLRVADFVLARCTKTQTAREIHDWVEYLKSLLASLPPVLTEMSRNPAHTSTAQQLQSLYHAWAGTTESLLQCFEQTVSMHEFLKLSIQEMAKHKEWCDKALQSQDPKRLSRHATSLTNWARWVAEAAARYVDRATDPIFRNGLLVWVEQLAKSNLELKAATALCTERCSCLQARDVFSKTVSCLMDTAHCIRDGLDGSNHPDILSPL", "length": 635, "header": "tr|A0A8V0Z5U7-1|A0A8V0Z5U7_CHICK Isoform 1 of CTNA1 protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z5U7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7/entry#A0A8V0Z5U7-1", "sequence": { "sequence": "MEPFYLYDLGIQIENKAIQRILCPMATELCHLILALEQEDGMRQTLPNIEENAEKLAKATDELASAARRLAEQSGDKVYQEETHLTAESLVLAGRHVLQAARQLQGKPDSPTHREALAAAAKGVLTETVKILQIEGAAGARRIMQAASWLLECLGTLRDTRDMPGLLAAFQDFSKALLLLSNLTAKHLEELQDSPRRTSLAQTLQLLQKCIPLLHESKHSHLKCSWAQQVNFSKNYAFQLMERTIQELVSLLVNSTGSKELQDRHGTFSHHVHRLLALLSHPEPVHLSDSEFSAHVEAVVFYCMLLAEMCRADLKKDLVKHCWVLLRLRKSICCHISQEGRTRPSWGENSLREKCHSMGKEVEDLDQAVLKATLHKILDTFSEAKEPLRQLVEEALTLAGTGCFLAGQGGLLKKLQPLTATFFAQAQQMLRVADFVLARCTKTQTAREIHDWVEYLKSLLASLPPVLTEMSRNPAHTSTAQQLQSLYHAWAGTTESLLQCFEQTVSMHEFLKLSIQEMAKHKEWCDKALQSQDPKRLSRHATSLTNWARWVAEAAARYVDRATDPIFRNGLLVWVEQLAKSNLELKAATALCTERCSCLQARDVFSKTVSCLMDTAHCIRDGLDGSNHPDILSPL", "length": 635, "header": "tr|A0A8V0Z5U7-1|A0A8V0Z5U7_CHICK Isoform 1 of CTNA1 protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z5U7-1" }, "locus": { "chromosome": "3", "start_pos": 3452442, "end_pos": 3449954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043564.1", "url": "https://www.ensembl.org/id/ENSGALT00010043564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025913.1", "url": "https://www.ensembl.org/id/ENSGALP00010025913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5U7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 254, "end_pos": 256 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5V1-1", "uniprot_ac": "A0A8V0Z5V1", "uniprot_id": "A0A8V0Z5V1_CHICK", "mass": { "chemical_mass": 224080.0, "monoisotopic_mass": 224080.0 }, "refseq": {}, "gene_names": [ { "name": "EML5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" } ] } ], "protein_names": [ { "name": "EMAP like 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1", "locus": { "chromosome": "5", "start_pos": 42675861, "end_pos": 42773390, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018027", "url": "https://www.ensembl.org/id/ENSGALG00010018027" } ] } } ], "crossref": [ { "id": "ENSGALG00000010639", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010639", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423400", "url": "https://www.ncbi.nlm.nih.gov/gene/423400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5V1", "url": "https://www.orthodb.org/?gene=A0A8V0Z5V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C683", "url": "https://www.orthodb.org/?gene=E1C683", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C683", "url": "https://www.uniprot.org/uniprotkb/E1C683", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C683-1", "url": "https://www.uniprot.org/uniprotkb/E1C683-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQRRSDSEARPVSPFPRGLLRERAVPAWRGREDMADRSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYLGHQDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNTVCVWDWRKGKLLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNSLTPKRGVFGKTGDLQTILCLACARDEVTYSGALNGDIYVWKGINLVRTIQGAHAAGIFSMNACEEGFATGGRDGCVRLWDLNFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAMTGSDDRSVRIWSLIDHALIARCNMEEPIRCAAVSTDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGNFLAVGSNDSSVDIYGVVQRYKKVGECIGSLSFITHMDWSSDSKYIQTNDGNGKRLFYRMPSGKEVTNKEELKGVQWASWTCVSGVEVNGIWPKYSDINDINSVDANFIGQVMVTADDYGIVKLFRYPCLRKGAKFKKYLGHSAHVTNVRWSHDHQWVVSIGGADHSVFQWKFVPDRKLKDSLHIAPQESLVDSNSDESDSDQSDVPELDSEIEQETQITYRRQVYKEDLPQLKEQCKEKRKSAASKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQTGEIVYHVAAVGVVYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDSSIHIWDTETIKPLSVLKGYHQYGVCAVDFSADGKRLASVGIDDNHTIVLWDWKKGEKLSAVRGSKDKIFVVKINPYMPEKLITVGIKHLKFWRRAGGGLIGRKGCIGAMGRADTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLIKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDTFERCLKTYAIKRAALAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPHLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLIVNADTLEDLVSFQHRKDVISEIRFSPGAGKYLAVASCDNFVDIYNVMSSKRVGICKGASSYITHLDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPTLEVEKIGWASWTSVLGSCCEGIWPIIGEVTDVTASCLTSDSKVLATGDDFGFVKLFRYPAKGKFGKFKRYVAHSTHVTNVRWTYDDSLLVTVGGADTSLMLWTYEMEGHRDSRQCDSEESDLDSEEDGGYDSDVTRENEINYTIKALSTNIRPMFGIKPHLQQKEPTLDERQGVVRGSRPPVSRALPQPEKLQTNNVGKKKRPIEDLILELVFGYRGKDCRNNVHYLNDGADVIYHTASIGILYNVATGSQSFYQEHNDDILCLTVNQHPKFTNIVATGQVGDSADMSATAPSIHVWDAMNKQTLSVLRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWKWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVRFWTLAGRALLSKKGLLSSIEDARMQTMLSVAFGANNLTFTGTISGDVCVWKDHVLIRIVAKAHNGPVFTMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELKRCRAFRLETGQITDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNILINGHMDGPIWGLATHPSRDFFLSAAEDGTVRLWDIAEKKMLNKVSLGHAARTVCYSPEGDMVAIGMKNGEFIILLVTSLKIWGKKRDRRSAIQDIRFSPDSRYLAVGSSENAVDFYDLTLGPTLNRVSYCKDIPSFVIQMDFSADSCYLQVSTGSYKRQVYEVPSGKQLVDQAVIDRITWATWTSVLGDEVIGIWSRHAEKADVNCACVSHSGINLVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSAHLTNIRFTSGDRYVVSAGGDDCSLFIWKCVHMPH", "length": 2011, "header": "tr|A0A8V0Z5V1-1|A0A8V0Z5V1_CHICK Isoform 1 of EMAP like 5 OS=Gallus gallus OX=9031 GN=EML5 PE=3 SV=1 CANONICAL=A0A8V0Z5V1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1/entry#A0A8V0Z5V1-1", "sequence": { "sequence": "MSQRRSDSEARPVSPFPRGLLRERAVPAWRGREDMADRSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYLGHQDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNTVCVWDWRKGKLLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNSLTPKRGVFGKTGDLQTILCLACARDEVTYSGALNGDIYVWKGINLVRTIQGAHAAGIFSMNACEEGFATGGRDGCVRLWDLNFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAMTGSDDRSVRIWSLIDHALIARCNMEEPIRCAAVSTDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGNFLAVGSNDSSVDIYGVVQRYKKVGECIGSLSFITHMDWSSDSKYIQTNDGNGKRLFYRMPSGKEVTNKEELKGVQWASWTCVSGVEVNGIWPKYSDINDINSVDANFIGQVMVTADDYGIVKLFRYPCLRKGAKFKKYLGHSAHVTNVRWSHDHQWVVSIGGADHSVFQWKFVPDRKLKDSLHIAPQESLVDSNSDESDSDQSDVPELDSEIEQETQITYRRQVYKEDLPQLKEQCKEKRKSAASKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQTGEIVYHVAAVGVVYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDSSIHIWDTETIKPLSVLKGYHQYGVCAVDFSADGKRLASVGIDDNHTIVLWDWKKGEKLSAVRGSKDKIFVVKINPYMPEKLITVGIKHLKFWRRAGGGLIGRKGCIGAMGRADTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLIKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDTFERCLKTYAIKRAALAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPHLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLIVNADTLEDLVSFQHRKDVISEIRFSPGAGKYLAVASCDNFVDIYNVMSSKRVGICKGASSYITHLDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPTLEVEKIGWASWTSVLGSCCEGIWPIIGEVTDVTASCLTSDSKVLATGDDFGFVKLFRYPAKGKFGKFKRYVAHSTHVTNVRWTYDDSLLVTVGGADTSLMLWTYEMEGHRDSRQCDSEESDLDSEEDGGYDSDVTRENEINYTIKALSTNIRPMFGIKPHLQQKEPTLDERQGVVRGSRPPVSRALPQPEKLQTNNVGKKKRPIEDLILELVFGYRGKDCRNNVHYLNDGADVIYHTASIGILYNVATGSQSFYQEHNDDILCLTVNQHPKFTNIVATGQVGDSADMSATAPSIHVWDAMNKQTLSVLRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWKWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVRFWTLAGRALLSKKGLLSSIEDARMQTMLSVAFGANNLTFTGTISGDVCVWKDHVLIRIVAKAHNGPVFTMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELKRCRAFRLETGQITDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNILINGHMDGPIWGLATHPSRDFFLSAAEDGTVRLWDIAEKKMLNKVSLGHAARTVCYSPEGDMVAIGMKNGEFIILLVTSLKIWGKKRDRRSAIQDIRFSPDSRYLAVGSSENAVDFYDLTLGPTLNRVSYCKDIPSFVIQMDFSADSCYLQVSTGSYKRQVYEVPSGKQLVDQAVIDRITWATWTSVLGDEVIGIWSRHAEKADVNCACVSHSGINLVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSAHLTNIRFTSGDRYVVSAGGDDCSLFIWKCVHMPH", "length": 2011, "header": "tr|A0A8V0Z5V1-1|A0A8V0Z5V1_CHICK Isoform 1 of EMAP like 5 OS=Gallus gallus OX=9031 GN=EML5 PE=3 SV=1 CANONICAL=A0A8V0Z5V1-1" }, "locus": { "chromosome": "5", "start_pos": 42773232, "end_pos": 42679320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043574.1", "url": "https://www.ensembl.org/id/ENSGALT00010043574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025918.1", "url": "https://www.ensembl.org/id/ENSGALP00010025918.1" } ] } }, { "isoform_ac": "E1C683-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1/entry#E1C683-1", "sequence": { "sequence": "MADRSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYLGHQDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNTVCVWDWRKGKLLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNSLTPKRGVFGKTGDLQTILCLACARDEVTYSGALNGDIYVWKGINLVRTIQGAHAAGIFSMNACEEGFATGGRDGCVRLWDLNFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAMTGSDDRSVRIWSLIDHALIARCNMEEPIRCAAVSTDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGNFLAVGSNDSSVDIYGVVQRYKKVGECIGSLSFITHMDWSSDSKYIQTNDGNGKRLFYRMPSGKEVTNKEELKGVQWASWTCVSGVEVNGIWPKYSDINDINSVDANFIGQVMVTADDYGIVKLFRYPCLRKGAKFKKYLGHSAHVTNVRWSHDHQWVVSIGGADHSVFQWKFVPDRKLKDSLHIAPQESLVDSNSDESDSDQSDVPELDSEIEQETQITYRRQVYKEDLPQLKEQCKEKRKSAASKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQTGEIVYHVAAVGVVYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDSSIHIWDTETIKPLSVLKGYHQYGVCAVDFSADGKRLASVGIDDNHTIVLWDWKKGEKLSAVRGSKDKIFVVKINPYMPEKLITVGIKHLKFWRRAGGGLIGRKGCIGAMGRADTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLIKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDTFERCLKTYAIKRAALAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPHLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLIVNADTLEDLVSFQHRKDVISEIRFSPGAGKYLAVASCDNFVDIYNVMSSKRVGICKGASSYITHLDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPTLEVEKIGWASWTSVLGSCCEGIWPIIGEVTDVTASCLTSDSKVLATGDDFGFVKLFRYPAKGKFGKFKRYVAHSTHVTNVRWTYDDSLLVTVGGADTSLMLWTYEMEGHRDSRQCDSEESDLDSEEDGGYDSDVTRENEINYTIKALSTNIRPMFGIKPHLQQKEPTLDERPPVSRALPQPEKLQTNNVGKKKRPIEDLILELVFGYRGKDCRNNVHYLNDGADVIYHTASIGILYNVATGSQSFYQEHNDDILCLTVNQHPKFTNIVATGQVGDSADMSATAPSIHVWDAMNKQTLSVLRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWKWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVRFWTLAGRALLSKKGLLSSIEDARMQTMLSVAFGANNLTFTGTISGDVCVWKDHVLIRIVAKAHNGPVFTMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELKRCRAFRLETGQITDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNILINGHMDGPIWGLATHPSRDFFLSAAEDGTVRLWDIAEKKMLNKVSLGHAARTVCYSPEGDMVAIGMKNGEFIILLVTSLKIWGKKRDRRSAIQDIRFSPDSRYLAVGSSENAVDFYDLTLGPTLNRVSYCKDIPSFVIQMDFSADSCYLQVSTGSYKRQVYEVPSGKQLVDQAVIDRITWATWTSVLGDEVIGIWSRHAEKADVNCACVSHSGINLVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSAHLTNIRFTSGDRYVVSAGGDDCSLFIWKCVHMPH", "length": 1969, "header": "tr|E1C683-1|A0A8V0Z5V1_CHICK Computationally mapped isoform of EMAP like 5 OS=Gallus gallus OX=9031 GN=EML5 PE=3 SV=4 CANONICAL=A0A8V0Z5V1-1" }, "locus": { "chromosome": "5", "start_pos": 42772748, "end_pos": 42679320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043572.1", "url": "https://www.ensembl.org/id/ENSGALT00010043572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025916.1", "url": "https://www.ensembl.org/id/ENSGALP00010025916.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1616, "end_pos": 1618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 341, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V1" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 362, "end_pos": 626, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1616, "end_pos": 1618 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 829, "end_pos": 831 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5W8-1", "uniprot_ac": "A0A8V0Z5W8", "uniprot_id": "A0A8V0Z5W8_CHICK", "mass": { "chemical_mass": 41432.0, "monoisotopic_mass": 41432.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM52", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8" } ] } ], "protein_names": [ { "name": "Transmembrane protein 52", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z5W8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5W8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR038942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33955:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33955:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNTVTFFWLQTHCQRSIKTFSSVFLYVLTRLSKNTNYLLSQSFVTVFYSYFLIYFSLCLQNTSETSQPPAVCSAARKSHRYPFVKSNEQQSNTAPVKPLPAAFSPSGLLFYHVSNFTASIVRGRPTQSPAAAARSRAGTSGTPERVRGARRGPCGGAPQEITALRGPGGLGPASAPPRGGRLRSARRAAAPLCSSVDSTKDSDQCPQNMSNWTSLWYVWLILLTVFMLLLCGITASCKKFCCRKKRPPVQPFPRHPYDLTVVAIDSDSTAHSTVTSYSSFQYPPSAPIPSIFVGLDRSTVSPPAYSPYAMDLPPSYDEAVQMGKQHIEVALVNQKLSDIPGQVMPGGQNPIQNSPDIINRDPATQPNSEDATQEQPQL", "length": 379, "header": "tr|A0A8V0Z5W8-1|A0A8V0Z5W8_CHICK Isoform 1 of Transmembrane protein 52 OS=Gallus gallus OX=9031 GN=TMEM52 PE=4 SV=1 CANONICAL=A0A8V0Z5W8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W8/entry#A0A8V0Z5W8-1", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6W6-1", "uniprot_ac": "A0A8V0Z6W6", "uniprot_id": "A0A8V0Z6W6_CHICK", "mass": { "chemical_mass": 39875.0, "monoisotopic_mass": 39875.0 }, "refseq": {}, "gene_names": [ { "name": "FAM76A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W6" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 76 member A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM76A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W6", "locus": { "chromosome": "23", "start_pos": 2459349, "end_pos": 2444214, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018339", "url": "https://www.ensembl.org/id/ENSGALG00010018339" } ] } } ], "crossref": [ { "id": "A0A8V0Z6W6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6W6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR032017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5X1", "url": "https://www.orthodb.org/?gene=A0A8V0Z5X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6W6", "url": "https://www.orthodb.org/?gene=A0A8V0Z6W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5Y1-1", "uniprot_ac": "A0A8V0Z5Y1", "uniprot_id": "A0A8V0Z5Y1_CHICK", "mass": { "chemical_mass": 357070.0, "monoisotopic_mass": 357070.0 }, "refseq": { "ac": "XP_015143911", "name": "WD repeat- and FYVE domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143911" }, "gene_names": [ { "name": "WDFY4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1" } ] }, { "name": "WDFY4", "type": "synonym", "evidence": [ { "id": "XP_015143911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143911" } ] } ], "protein_names": [ { "name": "WD repeat- and FYVE domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143911" } ] }, { "name": "WDFY family member 4", 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This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143911.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143911" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDFY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1", "locus": { "chromosome": "6", "start_pos": 19318503, "end_pos": 19193983, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020109", "url": "https://www.ensembl.org/id/ENSGALG00010020109" } ] } } ], "crossref": [ { "id": "cd01201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01201", "database": "CDD", "categories": [ "Protein 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"https://omabrowser.org/oma/group/PREGARN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46108:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46108:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEAAELTWQLENSPCKAGQQEQSLDDVDKSKVPEQPTHRKDKLSQSHTLQWETLGRQFVEYEQVAPFLIPEEQQRRLLDFLPLFLKAWEQSAGVIVFPSVQLLASEVSKLLTKEIKRTLNGKSAEEARLALEHLLQQKGEVEDGHLLLKSVYLLSRADLRTMWNIIGSGLPAALLQCLYLFFTFPLKENSDGETNEGETQEMLVEIMLKMYREEQGVEELLAADKLQSLIIAAASLWDQCSHPWKVPTGRVLRTISKSQTKNSILHLQAVDCIKIAVQNLFKLADTLPACDVCEAVSIVLCFVKDSYPVSSALLTEFESNDGYQLLLKVLLRCEGLQQNEGDPYMNEILDMLTCLTTCGKTELKVSGNIIHPQLPQFDYEWTRSSGMTVKNLQAFQVLQSIFQKSDDQHLCGTVLGAIGTIWAWDTVNFFLLEWTLQPINQFIDIIHFKPHPVQVQFFRLVESIVLDLSYIPHEILKKVQCLIKENVVPFCTLTALRCLLSITKKDLLFSDIFRDSGLLGLLLALLRKQAKILRKSAGTSLPGLEEGTDKELNAVMLKMVAALTVGCVRNTVVLKDYGMVPYIKIFLDDECYRGATLSILEQLSVINYEEYMSIVIGALCSSTQGELHLKLDLLKSLLRILNSPKSHSAFRTCSGFNGLLSLLSDMEGALQDPPCGLWAAVGHNCILELVFYTLQGITAALHLDPVNSNFFQRNGLFEKMAEDLGSLGCFWTQGEWHNPLSLEKTRTFAEFLDAAFCSSEPLPTWLKNCIWILSFLDHMVKGTLHLEDYFKEIKSEMGEASRDDQEGTPAQGEHPVFSKRPVSELCASAYSLWGNSEEKWEMRDCVIVNPGAVCVMVRLLPKLYKEGHSQISQEIQCAVADHIQSLVKSEKSRQVMCGAGLLSTIITSCQDAFRNESHPLHLPLTRVFEKLASQSIEPDVLRQFLCLGGSLSVPSWTNTNNTEVLSCQESDSSEASLNEEKVAADNKTALQTAVPLSNSPWMSKGSALALQTAMSLISMTSPRNLQLHSTALAPSFVEFDMSMEGYGCLYLPTLATVLGPSAEQSVSGGIGMGSRMFPPSSGLTLSCWFLVSKFGVVHNSHPLRFLTIVRHMSRTEQEFVCFSVSFSPQDGSLVISTEEVEFQPLDIMEPEGEVQNISPFPEQVQFGCGKLLVTGQWHHLTVTVAKEAKKNCTVSAFINGQMLGSAKMRYFQTLPGSCVSMDPSSFIDVYGYIATPRVWKQKSSLIWRFGPTYLFEEAISVETIEMINKLGPQYCSNFQAVQLQGEIQYGEQNPAQLVAEEKISFGINAVCSSFSTIQDIKSAYNEVDGRLVAKEIGINSRDSSTPIFLAKNIAGHLSGSLRTIGSVAVGQYGVRVFKSSPAATSLNFIGGPSILLGLIAMASDDHTMYAAVKVLNSILNSSPMSEKMMRHIGGYRLLTYLLKRKTQLLNNRILQLMFSLVGTAELGFGSSVIKNYNAFQYILCNFELWMKAPENLDLTLFAHLVEILQCSRVGCQNAEVAHRVQVVPKLIFLFNDPEISNSRITVVCTILSHLLQGYFNTKDVLRIGLFLVYTLKPSSVDENQLCLDSTAEMPSEALSQTSGKTIWLRNQLLKMLLDVICSAKFHLSSEAQEEVFLALGPDWFLLFTQSYLHSSTVVLGIKLLLYFLHNRLLLNKFKEGIVAGHWLENSTAGLSILMDNLKTHPLVPDSGSILIFGFSVLQKCLTDHVHIPEIYLLVAGLFLATPHSEPPEAAKGDLDSMLQWILQQHATENVLKNGLCAEAAALLLEMVRVTVDKPIAGAEASWEIVYPGNVIQFLYLIYHTYTQDPVWHCPDFLKTLAMVAFHSEPPKGGSEGLLTPDGPAIAEGKGCTDSSSLPLLPHPAKKQVWDFLHVLLMDSLLNIPANKQGHPLELLLEASPEDATSEQKRHFQTKVLLSAMDVFHVISQGEGKTRPRGNSDLHSSSESTASVSMTNVTYLAQKLIEKINSKMFAADSKQVLLFIAKQITRVLEAPVSQKDVFLSTMYSCLNRAILYCLSRPQQSLTEQFNLLNILSVLQEQWDIIFATYNSSNNFIICLMHCLCQLNSGSYPEGFGVDAKPKLPSHHQIFLAPSEEEKGSLPTPADVHQEILRAIEIIWKQLISQRRQALEDIYNMDLSVKGSDRERDMKITEITPLWEEMMTKAWQNFLASEKRVLQNKSVLGLSQSKHNSWSESLSSAMRLMPSRNTKEMPCKSEGFVSCMERYRRTGQELYASLYRNHVQVLQCGYSKAAKDWMVLEEQLFHRRGPWGVVSQSLEPRWILDCYEGPSRMRRRIQQASNRATVMRMKSEVLLANRNATTSTAEVDSGELMLNGAEKERDEKGLDCNQLTFFPALHESFHSEDFLELCVERQIILQEFAENEKVTFKCSVAVVQGHTALEGVLLFGREHFYICECFVLSPLEEVCCTQHCLSSISDPFIFNLCHKDHVVGDQRCSRYSYCDIKEIRLMRFLLQEIALEIFFKNGYSRFLVFHDCDRKKIFKRFCFFQPALKSKGVTEESVNIRKHSGGEKTMLQKWQKREISNFDYLMYLNTLAGRSYNDYMQYPVFPWVLADYHSQTLNLSNPHTFRDLSKPMGAQTTERKQKFIQRYKEVEKSEGDLSAQCHYCTHYSSAIIVASYLVRLEPFTQTFCSLQGGSFDVADRMFHSVKSTWESASRDNMSDVRELIPEFFYLPEFLTNANHFEFGCMQDGTVLGDVQLPPWADGDPHKFILLHRQALESDYVSAHLHRWIDLIFGHKQQGSAAVEAVNTYHPYFYGDKMDLNNIKDPLIKSTILGFISNFGQIPKQLFTKPHPPRTVQSKSSSGREAVLSFQSSGILPPFMSSLQNLKLSPVTVKEYSKGAVGHIVHTEKGVLAVEKNKVLIPPLWNKTFCWGFDDFTCCFGNYGSEKNMTTFECMADWGKCICAVCPSATTIITSGTSSVVCVWELSLVKDKVKRLSLRQALYGHSQAVTCLAASVTYSIIVSGSDDRTCIIWDLNHLTYITQLPAHEASLSSVAINNSTGDIASCAGSYLHLWTVNGQPLVSVNTTCSPKSCIACCCFAEVMDWDTRSIIITGSTDGVVRLWKTEYPTCPGQAADLSSQGGTVGEESSPGNKCGKQLVLFRELNPSLTLTGKPSKNSPAVTALAVSRNSSKLLVGDEWGRIYCWSVDG", "length": 3191, "header": "tr|A0A8V0Z5Y1-1|A0A8V0Z5Y1_CHICK Isoform 1 of WDFY family member 4 OS=Gallus gallus OX=9031 GN=WDFY4 PE=1 SV=1 CANONICAL=A0A8V0Z5Y1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1/entry#A0A8V0Z5Y1-1", "sequence": { "sequence": "MDEAAELTWQLENSPCKAGQQEQSLDDVDKSKVPEQPTHRKDKLSQSHTLQWETLGRQFVEYEQVAPFLIPEEQQRRLLDFLPLFLKAWEQSAGVIVFPSVQLLASEVSKLLTKEIKRTLNGKSAEEARLALEHLLQQKGEVEDGHLLLKSVYLLSRADLRTMWNIIGSGLPAALLQCLYLFFTFPLKENSDGETNEGETQEMLVEIMLKMYREEQGVEELLAADKLQSLIIAAASLWDQCSHPWKVPTGRVLRTISKSQTKNSILHLQAVDCIKIAVQNLFKLADTLPACDVCEAVSIVLCFVKDSYPVSSALLTEFESNDGYQLLLKVLLRCEGLQQNEGDPYMNEILDMLTCLTTCGKTELKVSGNIIHPQLPQFDYEWTRSSGMTVKNLQAFQVLQSIFQKSDDQHLCGTVLGAIGTIWAWDTVNFFLLEWTLQPINQFIDIIHFKPHPVQVQFFRLVESIVLDLSYIPHEILKKVQCLIKENVVPFCTLTALRCLLSITKKDLLFSDIFRDSGLLGLLLALLRKQAKILRKSAGTSLPGLEEGTDKELNAVMLKMVAALTVGCVRNTVVLKDYGMVPYIKIFLDDECYRGATLSILEQLSVINYEEYMSIVIGALCSSTQGELHLKLDLLKSLLRILNSPKSHSAFRTCSGFNGLLSLLSDMEGALQDPPCGLWAAVGHNCILELVFYTLQGITAALHLDPVNSNFFQRNGLFEKMAEDLGSLGCFWTQGEWHNPLSLEKTRTFAEFLDAAFCSSEPLPTWLKNCIWILSFLDHMVKGTLHLEDYFKEIKSEMGEASRDDQEGTPAQGEHPVFSKRPVSELCASAYSLWGNSEEKWEMRDCVIVNPGAVCVMVRLLPKLYKEGHSQISQEIQCAVADHIQSLVKSEKSRQVMCGAGLLSTIITSCQDAFRNESHPLHLPLTRVFEKLASQSIEPDVLRQFLCLGGSLSVPSWTNTNNTEVLSCQESDSSEASLNEEKVAADNKTALQTAVPLSNSPWMSKGSALALQTAMSLISMTSPRNLQLHSTALAPSFVEFDMSMEGYGCLYLPTLATVLGPSAEQSVSGGIGMGSRMFPPSSGLTLSCWFLVSKFGVVHNSHPLRFLTIVRHMSRTEQEFVCFSVSFSPQDGSLVISTEEVEFQPLDIMEPEGEVQNISPFPEQVQFGCGKLLVTGQWHHLTVTVAKEAKKNCTVSAFINGQMLGSAKMRYFQTLPGSCVSMDPSSFIDVYGYIATPRVWKQKSSLIWRFGPTYLFEEAISVETIEMINKLGPQYCSNFQAVQLQGEIQYGEQNPAQLVAEEKISFGINAVCSSFSTIQDIKSAYNEVDGRLVAKEIGINSRDSSTPIFLAKNIAGHLSGSLRTIGSVAVGQYGVRVFKSSPAATSLNFIGGPSILLGLIAMASDDHTMYAAVKVLNSILNSSPMSEKMMRHIGGYRLLTYLLKRKTQLLNNRILQLMFSLVGTAELGFGSSVIKNYNAFQYILCNFELWMKAPENLDLTLFAHLVEILQCSRVGCQNAEVAHRVQVVPKLIFLFNDPEISNSRITVVCTILSHLLQGYFNTKDVLRIGLFLVYTLKPSSVDENQLCLDSTAEMPSEALSQTSGKTIWLRNQLLKMLLDVICSAKFHLSSEAQEEVFLALGPDWFLLFTQSYLHSSTVVLGIKLLLYFLHNRLLLNKFKEGIVAGHWLENSTAGLSILMDNLKTHPLVPDSGSILIFGFSVLQKCLTDHVHIPEIYLLVAGLFLATPHSEPPEAAKGDLDSMLQWILQQHATENVLKNGLCAEAAALLLEMVRVTVDKPIAGAEASWEIVYPGNVIQFLYLIYHTYTQDPVWHCPDFLKTLAMVAFHSEPPKGGSEGLLTPDGPAIAEGKGCTDSSSLPLLPHPAKKQVWDFLHVLLMDSLLNIPANKQGHPLELLLEASPEDATSEQKRHFQTKVLLSAMDVFHVISQGEGKTRPRGNSDLHSSSESTASVSMTNVTYLAQKLIEKINSKMFAADSKQVLLFIAKQITRVLEAPVSQKDVFLSTMYSCLNRAILYCLSRPQQSLTEQFNLLNILSVLQEQWDIIFATYNSSNNFIICLMHCLCQLNSGSYPEGFGVDAKPKLPSHHQIFLAPSEEEKGSLPTPADVHQEILRAIEIIWKQLISQRRQALEDIYNMDLSVKGSDRERDMKITEITPLWEEMMTKAWQNFLASEKRVLQNKSVLGLSQSKHNSWSESLSSAMRLMPSRNTKEMPCKSEGFVSCMERYRRTGQELYASLYRNHVQVLQCGYSKAAKDWMVLEEQLFHRRGPWGVVSQSLEPRWILDCYEGPSRMRRRIQQASNRATVMRMKSEVLLANRNATTSTAEVDSGELMLNGAEKERDEKGLDCNQLTFFPALHESFHSEDFLELCVERQIILQEFAENEKVTFKCSVAVVQGHTALEGVLLFGREHFYICECFVLSPLEEVCCTQHCLSSISDPFIFNLCHKDHVVGDQRCSRYSYCDIKEIRLMRFLLQEIALEIFFKNGYSRFLVFHDCDRKKIFKRFCFFQPALKSKGVTEESVNIRKHSGGEKTMLQKWQKREISNFDYLMYLNTLAGRSYNDYMQYPVFPWVLADYHSQTLNLSNPHTFRDLSKPMGAQTTERKQKFIQRYKEVEKSEGDLSAQCHYCTHYSSAIIVASYLVRLEPFTQTFCSLQGGSFDVADRMFHSVKSTWESASRDNMSDVRELIPEFFYLPEFLTNANHFEFGCMQDGTVLGDVQLPPWADGDPHKFILLHRQALESDYVSAHLHRWIDLIFGHKQQGSAAVEAVNTYHPYFYGDKMDLNNIKDPLIKSTILGFISNFGQIPKQLFTKPHPPRTVQSKSSSGREAVLSFQSSGILPPFMSSLQNLKLSPVTVKEYSKGAVGHIVHTEKGVLAVEKNKVLIPPLWNKTFCWGFDDFTCCFGNYGSEKNMTTFECMADWGKCICAVCPSATTIITSGTSSVVCVWELSLVKDKVKRLSLRQALYGHSQAVTCLAASVTYSIIVSGSDDRTCIIWDLNHLTYITQLPAHEASLSSVAINNSTGDIASCAGSYLHLWTVNGQPLVSVNTTCSPKSCIACCCFAEVMDWDTRSIIITGSTDGVVRLWKTEYPTCPGQAADLSSQGGTVGEESSPGNKCGKQLVLFRELNPSLTLTGKPSKNSPAVTALAVSRNSSKLLVGDEWGRIYCWSVDG", "length": 3191, "header": "tr|A0A8V0Z5Y1-1|A0A8V0Z5Y1_CHICK Isoform 1 of WDFY family member 4 OS=Gallus gallus OX=9031 GN=WDFY4 PE=1 SV=1 CANONICAL=A0A8V0Z5Y1-1" }, "locus": { "chromosome": "6", "start_pos": 19318164, "end_pos": 19203958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048576.1", "url": "https://www.ensembl.org/id/ENSGALT00010048576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028667.1", "url": "https://www.ensembl.org/id/ENSGALP00010028667.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2123, "start_aa": "Thr", "end_pos": 2123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2123", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423781", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423781", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A748-1", "protein_name": "WDFY family member 4", "gene_name": "Wdfy4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAEDCSKAEDRPEDPGFQNEGQSSAVKPTFSLEEQSPGPTVLWDMLEQKFLEYQQLIHKNPEERRRNLLSLLPLFLKAWEHSVGIICFRSLQRLAEDVSDQLAQEIQQALSGKPAEQARAAAGQLLQWKSDVDQDGYLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFPVEKGEHLEIDVQGQRMFVQMLLNICSESQGLEGLLSGSELQSLLIATTCLREHSCYFWKQPTFCVLRAISKAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGVTQGVVEPHLEELIELVMWLTTCGRSELKVFDSITYPQLEGFKFHQEASGVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFVEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQGLIKDSQELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPGVQDLERELTCVMLKTVVALLQGSVRNAVVLKDHGMVPFIKIFLDDECYRGSALSILEQLSVINAEEYMSIIVGALCSSTQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQLPAVTTCSAVSPSQTLELVLHTLCVVSAALHLDPVNKHFFRSNGLFEKLAEDLCLLGCFGAPEEEGAQRYSSSDMKARPFVDLLSGAFSSSCQFPPRVQSCLQILSFLESMAGGTLHLHRDLMEPSKAGQVPSLDARKGEPGSRQGKFKQWPDPEERMDEGDVTIMHPGIICIMVRLLPRLYLGDHPQLSEEIQCSMAHHLLSLVKSEKNRQVMCEAGMLRTLMTFCHRTLSTGGSALHSVLIRIFEKLGSQAIEPDVLRQFLDLGVRPPPSTARKSLHLSPGHEDGPGRSGSLADTSVKSTHASPCPRGSQDLRSSPTSEDSATALQTTLSLISMTSPRNLQSQRAALTPSFVEFDMSAEGYGCLFIPTLSTVMGTSTEHSISGGTGSGAPRPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSVSLCMDDLSLVVSTEEKEFQPLDIMEPEDEAEPSAGRQLQVRCSQLLACGQWYHLAVVVSKEMKRNCTVTMYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISPDTLELIIKLGPRYCGNFQAVHLQGDVPDGEATPLISEERVSFGLYVPSSSITSIINIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLFGSLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSNAMCDYLMQHIDGYQILAFLLRKKTPFLNHRIFQLILSVAGTAELGFRPSAVTNMCIFRHVLCNFELWTNTADNLELTLFSHLLEILQSPREGPRNAERAHQAQLVPKLIFLFNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLDGVQDPSAPAGSQTSGKAIWLRNQLLEMLFGVITAPQLHLSSELKEQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPSLCGRFRDGLSAGCWVESCLEGVDIMMDNLKNHPAVPDQSPCLLPGFRVLNDFLGYHVLIPEVYLIVSAFFLQMPLTELTDGPRESLDLMIQWLLQKHYQQEVLQAGLCIEGALLLLGMLKAIMSQPRAGSGDGTWEQTLPSSILQFLGLVHRSYPQDPAWRSPDFLQTMAIITFSVETQKEATSESSRNTSRPGSSAEASHSAEGFQASFKPHPAQRQLREFMQVLLRELLFGVSSPKQWLPLEVLLEASPDGATSQQKRDFQSEVLLSTMDIFHVPSGSGTPTLRGSKEPQSNAEAGTVPSLASVSYFTQKLVEKLHSGMFSANPKHILLFITEHIISVIENPSSQKDTVMSALYSSLNKVILHCLSKPQQSLSECLGLLSILDFLQEQWDIIFATYNSNVNFLLCLMHCLLLLNARSYPEGFGLEPKPRINPYHQVFLSPSEEVKDKKEEGLPSLGDVQHSIQKSVRALWQQLVAQRRQTLEDAFKIDLSVKAGESEVKIEEVTPLWEETMLRAWQHYLASEKKSLASRSSVTHHSKATSWSGSLSSAMRLMPGRQAKDPECRAEDFVSCIENYRRKGQELYASIYKDYVQRRKRDSIKAATAWARMQEQLFGELGLWGRMRESTSCSQWELDRREGPARMRKRIRRLCAWETLNLGSCKESQDQRGDVSQTNAENQVCPVFRIADELTIEEAESRPDEVGVDCTQLTFFPALHESLHSEDFLELCRERQIILQELLDGEKVSQKVPMVIVQGHLVSEGILLFGQQHFYVCENFTLSPTGDVYCTHHCLSNISDPFIFNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKAFKSFCTFQPSLKGKGTTEDPFNLRRHPGFDRTMLQKWQKREMSNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQSKERKLKFTQRFKDIEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKNTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGRMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLSSITDPLIKSTILGFVSNFGQVPKQIFTKPHPSRNTTGKSPVPGKETSTPTGLPGHSQSFLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTEKSILAVEKNKLLMPPLWNRVFSWGFDDFTCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIITSGASAVVCVWELSLVKGRPKGLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDCTCMLWDLDHLSRVACLPVHREGISAVAISDVSGTIVSCAGAHLSLWDVNGQPLASITTAWGPEGAITCCCIVERPAWDASHVIITGSKDGMVRIWKTEDMKMSVPRQAVMEEPSTEPLSPRGHKWAKNLALSRELDVSVALSGKPSKASPAVTALAVTRNQAKLLVGDEKGRIFCWSADG", "length": 3187 }, "evidence": [ { "id": "A0A8V0Z5Y1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q2M9-1", "protein_name": "WD repeat- and FYVE domain-containing protein 4", "gene_name": "Wdfy4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAEDLSKTEDRPEDPGFQNEGQSPAVKPSFSLEGQSPGPSVLWDMLEQKFLDYQQLMPRNPEERRKNLLSLLPLFLKAWEHSVGIICFRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQWKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFPVEKDDLLESDVQGQRMFVQMLLNICSESQGLEGLLSGSELQSLLIATTCLREHSCLFWKQPTFCVLRAISKAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVEPHLEELIELVMWLTTCGRSELKVFDSVTYPQLEGFKFHQEASGVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHGMVPFIKIFLDDECYRGPSLSILEQLSVINAEEYMSIIVGALCSSTQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGTPEEERTRWDSSSDMKARPFMDLLSCAFSSSCQFPPRLQSCLQILSFLESMASGTLHLRGDLMEPARAGQEPSVDAQKAEAGGRQGKFKQWPDMEDRMDEGDVMIMHPGIICIMVRLLPRLYLEDHPQLSEEIQCSVARHLLSLVKSEKNRQVMCEAGMLRTLMTFCPRTLSTGGSDLHSILIRIFEKLGSQAIEPDVLRQFLGLGIRPPRSAAVKSLHLPPGHEDNPGCSGSCAATAEKPTDSSPRPGGSQALRPSWASQYSATALQTTLSLISMTSPRNLQPQRAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAPRPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMDDLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVRCSQLLTCGQWYHLAVVVSKEMKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSNAMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVTNMCIFQHVLCNFELWTNTADNLELTLFSHLLEILQSPREGPRNAEVAHQAQLLPKLLFLFNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLDGAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSELKEQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIVMDNLKSRPAVPDQSPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRENLDLMLQWLLQKHHQQEVLQAGLCIEGALLLLGMLKAIMNQPPAGSGDGAWEQTLPSSVLQFLRLVHRSYPQDSAWRTPDFLQTVAIITFPLETQKETTSESSRNTSSPGASAEASHAAEGFQASFQPHPALRQLREFMQVLLRELLLGGSNPKQWLPLEVILEASPDGATSQQKRDFQTEVLLSTMDIFQVPSGDGMPTLRGSKEPLPNAEAGAVPSLASVSYFTQKLVEKIYSGVFSADPRHILLFITEHIIAVIENPSSQKDTVMSALYSSLNKVILHCLSKPQQSLSECLGLLTILDFLQEHWDIIFATYNSNVSFLLCLMHCLLLLNARSYPEGFGLEPKPRITPYHQVFLSPNEEVKDKKEEGLPSLGDVQHSIQKSVRALWQQLVAQRRQTLEDAFKIDLSVKAGEIEVKIEEITPLWEETMLRAWQHYLASEKKSLASRSSVMHHSKVTSWSGSLSSAMRLMPGRQAKDPECRAEDFVSCIENYRRKGQELYASIYKDYVQRRKSGSIKAATAWARMREQLFGELGLWGQMTESTRCSRWELDGREGPARMRKRIRHLLAWEPLNLGYKESQEGKGDVSQTNTGNQVFMTADELTTEEAESRPDEVGVDCTQLTFFPALHESLHSEDFLELCRERQVILQELLDGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFIFNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTFQPSLKGKGTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGKDASTPVGLPGHSQSFLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTEKSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPRGLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPRQAVMEEPSTEPLSPRGHKWAKNLALSRELDVSVALSGKPSKASPAVTALAITRNQSKLLVGDEKGRIFCWSADG", "length": 3183 }, "evidence": [ { "id": "A0A8V0Z5Y1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MG90-1", "protein_name": "WDFY family member 4", "gene_name": "WDFY4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAKDVSEAEDRAEDPGSKNKGQPDAVQPDFPPGGQTPGPTALWEMLERKFLEYQQLASRSPAEQQKSLLNLLPLFLKAWEHSVGIICFPSLQRLAEDVSNQFAQEIQKALVGKPAEQARVAAGKLLQWKGDADVHQEGHLLLKSVYVLTGTDAETLGRVAESGLPALLLQCLYLFFVFPLETDELLESDVQVQRMFVQMLLNICGEAQSLEGLLSGNELQSLMIATTCLREHSCCFWKEPTFCVLKTISKAQNVGVIQYLQAMDCIKISLQNLSRLVDTLPAPEVSEVVSLVLGFVKDSYPISSALFLEFETGEGYPLLLKVLLRYDGLTQSEADPHLEELLGLVVWLTTCGRSELKVFDSITYPQLEGFKFHQEASGVTVKNLQAFQVLQNVFHKVSDPIICTKVLSSIRTMWTWNPRNFFLLEWTLQPISQFVEIVPLKPTLVQRHFFQMLEALVFELRYVPHEILRKVQRLIQESPESLCTLVALQSVLRIAGGDPLFTDIFRDSGLLGLLLAQLRKHAKILRKSGNKEVNPGVQDTERELTCVMLKTVVTLLKGSVRNAVVLKDHGMVPFIKIFLDGECYRAASLSILEQLSVINAEEYMSIIVGALCSSTQGEIQLKLDLLKSLLRILETPKGRAAFRVSSGFNGLLSLLSDLEGSLQEPPLQTWGAVSPSQTLDLVLHTLCALSAALHLDPVNGDFFRRTGLFEKLAEDLCLLGCFGALEEEDAPPPSREDTKARPFADLLSAAFSSASLLPPKIQSCLQILSFLDSMARGTLHLRRDLKDAPRTRQELAVDPQRAEPGSDPQGSFTQWPDLEERTDDSDAVIMHPGVLCIMVRLLPRLYHEDHPQLSREIQCSMASHIQSMVKSEKNRQVMCEAGMLRTLMTSCHKALTTSSSPLHSGLIRIFEKLASQAIEPDVLRQFLGLGIASPPSAATKKLSSSHACGGDSGCPGSQAAMPVPAEGSAVAPGDAGPHPASTQALKPMGLSQTSTTTLQTALSLISMTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFVPTLATVMGTSTEYSVSGGIGTGAARSFPPPGGLSFSCWFLVGRHSTAAEGHPLRFLTLVRHLARTEQPFVCFSVSLCPEDLSLVVSTEEKEFQPLDVMELEDDPEPSAGRQLRVRCGQLLACGQWHHLAVVVTKEMKRNCTVFTYLDGQVIGSAKMLYIQALPGPFLSMDPSSFVDVYGYIATPRVWKQKSLLIWRLGPTYFFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDPGVEAMPLVAEEKVSFGLHIASSSVTSVADIRSTYNEVDSRLIAKEMNISSRDSVVPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHSMYAAVKVLHLVLTSNVMCDRLMQHICGYQIMAFLLRKKTSFLNHRIFQLILSITGTAELGFGPSVITNVGVFQHILCNFELWMNAADNLELSLFSHLVEILQSTREGPRNAEVAHQAQLIPKLVFLFNEPGLTPSKMRTVIAILGCQLRGHFSLQDLLRIALFVVYTLKPSSLNEKQICVDRAPDPSLPAGSQTSGKTIWLRNQLLEMLLSVISSSQLHLSSETKEEMFLNLGSDWFLLFVQGHMHPSTVVLGLKLLLHFLSSPSLRGRFKDGLPAGSWVERSSEGMDIVMDNLKSHPPTPDQSPCLLPGFRVLSDFLAHHVHIPEVYLIVSTFFLQTPLTELTDGPKDSLDAMLQWLLHKHHREEVLRAGLCTEGALLLLEMLKATMSQPSTGSGDSAWERTFPASVLQFLGLVHSAYPQDPAWRAPEFLQTLAAVTFPLGTQKGAVTESAQSTSSPEAEAEGDDAAEGLQAPAESHPTRKQLKEFMQLLLREFLLGAPNPKQWVPLEVLLEASPDNATTQQKRDFQSEILLSTMEIFHVMSGGHASMLRGSREPQPDAEAAAAPSLANISHFIQKLVEKLYSGMFSADPRHILLFITEHIMVVIENASAQKDTAISALYSSLNKVILYSLSKPHQSLSECLSLLSTLGFLQEHWDILFATYNSNASFLMCLMHCLLLLSARSYPEGFGLEPKPRMTPYHQVFLSPNEEVREKRGEEFPSLSDVQHNIQKTVRILWQQLVAQRRQELEDTFKIDLSVKPGESEVKIEEITPLWEETMLKAWQHYLASERKSLASRSNVGHHSKVSSWSGSLSSAMRLMPGRQTKDPECKAEDFVSCIENYRRRGQELYASLYKDHVQRRRCGNIKAANAWTRIQEQLFGELGLWHQMAEATPCSQWELDWREGPARMRKRIRRLSPLEAPNQERLKESQDRNGNVSQINTEHQDELTLKEGESEADEVAGCTQLTFFPALHESLHSEDFLELCQERQVILQELLDHEKVTQKYSVVIVQGHLVCEGLLLFGQQHLYICENFTLSPVGDVYCTRHCLSNISDPFIFNMCSKDRSSDHYSCQRHSYGDLRELRQARFLLQDIALEVFFQNGYSKFLVFHNSDRSKVFKSFCSFQPSLKGKGFTEDTLNLRRYPSSDRTMLQKWQKRDISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSQTLNLMNPKTFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDVTARCHYCTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKNAWESASRENMSDVRELTPEFFYLPEFLTNCNALEFGCMQDGTALGDVQLPPWADGDPRKFISLHRQALESDFVSANLHHWIDLIFGYKQQGSAAVEAVNTFHPYFYGDKVDLSSISDPLIRSTILGFVSNFGQVPKQLFTKPHPARTAAGKPSPGKDVSTPASLPGHPQPFLYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIVPTEKTILAVETNKMLLPPHWSRTFSWGFDDFSCCLGSYGSDKILVTFENLAAWGRCLCAACPSPTTIITAGTSAVVCVWELSMTKGRATGLRLKQALYGHTQAVTCLAASVTFSLLVSGSQDRTCILWDLDHLTHVARLPAHRDGVSAVAISDVSGTIVSCAGAHLSLWDVNGQPLASITTAWGPEGAITCCYVVEGPAWDTSHVIITGSRDGMVRIWKTEDVKMSVPGQAAPEEPWAPSSPSPRVHRWEKNLALCRELDVSVALTGKPSKANSAVTALAVSRNQTKLLVGDEKGRIFCWSAEG", "length": 3188 }, "evidence": [ { "id": "A0A8V0Z5Y1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZS81-1", "protein_name": "WD repeat- and FYVE domain-containing protein 4", "gene_name": "WDFY4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAEDLSKAEDRNEDPGSKNEGQLAAVQPDVPHGGQSSSPTALWDMLERKFLEYQQLTHKSPIERQKSLLSLLPLFLKAWEHSVGIICFPSLQRLAEDVSDQLAQQLQKALVGKPAEQARLAAGQLLWWKGDVDQDGYLLLKSVYVLTGTDSETLGRVAESGLPALLLQCLYLFFVFPLDKDELLESDLQVQKMFVQMLLNICSDSQGLEGLLSGSELQSLLIATTCLREHSCCFWKEPTFCVLRAISKAQNLSIIQYLQATDCVRLSLQNLSRLTDTLPAPEVSEAVSLILGFVKDSYPVSSALFLEFENSEGYPLLLKVLLRYDGLTQSEVDPHLEELLGLVVWLTTCGRSELKVFDSITYPQLEGFKFHHEASGVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLLEWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCTLMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPERELTCVMLRIVVTLLKGSVRNAVVLKDHGMVPFIKIFLDDECYREASLSILEQLSAINAEEYMSIIVGALCSSTQGELQLKLDLLKSLLRILVTPKGRAAFRVSSGFNGLLSLLSDLEGSLQEPPLQAWGAVSPRQTLELVLYTLCAVSAALHWDPVNGYFFRRNGLFEKLAEDLCLLGCFGALEEEGNLLRSWVDTKARPFADLLGTAFSSSGSLPPRIQSCLQILGFLDSMASGTLHLRGDLKESLRTKQGPVVDVQKGETGSDPQRNFKQWPDLEERMDEGDAAIMHPGVVCIMVRLLPRLYHEDHPQLSEEIQCSLASHIQSLVKSEKNRQVMCEAGLLGTLMASCHRALVTSGSPLHSRLIRIFEKLASQAIEPDVLRQFLGLGIPSSLSATTKILDSSHTHRGNPGCSGSQTAQGLAEGPWPAAPDAGLHPGVTQAPQPLGESQDSTTALQTALSLISMTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGATRPFPPPGGLTFSCWFLISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLCPDDLSLVVSTEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKEMKRHCTVSTCLDGQVIGSAKMLYIQALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDLDSEATPFVAEERVSFGLHIASSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLTSNAMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAGTVELGFRSSAITNTGVFQHILCNFELWMNTADNLELSLFSHLLEILQSPREGPRNAEAAHQAQLIPKLIFLFNEPSLIPSKISTIIGILACQLRGHFSTQDLLRIGLFVVYTLKPSSVNERQICMDGALDPSLPAGSQTSGKTIWLRNQLLEMLLSVISSPQLHLSSESKEEMFLKLGPDWFLLLLQGHLHASTTVLALKLLLYFLASPSLRTRFRDGLCAGSWVERSTEGVDIVMDNLKSQSPLPEQSPCLLPGFRVLNDFLAHHVHIPEVYLIVSTFFLQTPLTELMDGPKDSLDAMLQWLLQRHHQEEVLQAGLCTEGALLLLEMLKATMSQPLAGSEDGAWAQTFPASVLQFLSLVHRTYPQDPAWRAPEFLQTLAIAAFPLGAQKGVGAESTRNTSSPEAAAEGDSTVEGLQAPTKAHPARRKLREFTQLLLRELLLGASSPKQWLPLEVLLEASPDHATSQQKRDFQSEVLLSAMELFHMTSGGDAAMFRDGKEPQPSAEAAAAPSLANISCFTQKLVEKLYSGMFSADPRHILLFILEHIMVVIETASSQRDTVLSTLYSSLNKVILYCLSKPQQSLSECLGLLSILGFLQEHWDVVFATYNSNISFLLCLMHCLLLLNERSYPEGFGLEPKPRMSTYHQVFLSPNEDVKEKREDLPSLSDVQHNIQKTVQTLWQQLVAQRQQTLEDAFKIDLSVKPGEREVKIEEVTPLWEETMLKAWQHYLASEKKSLASRSNVAHHSKVTLWSGSLSSAMKLMPGRQAKDPECKTEDFVSCIENYRRRGQELYASLYKDHVQRRKCGNIKAANAWARIQEQLFGELGLWSQGEETKPCSPWELDWREGPARMRKRIKRLSPLEALSSGRHKESQDKNDHISQTNAENQDELTLREAEGEPDEVGVDCTQLTFFPALHESLHSEDFLELCRERQVILQELLDKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFIFNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQPSLKGKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTAAGKPLPGKDVSTPVSLPGHPQPFFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIVSTEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPRGLRLRQALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSVPGRPAGEEPPAQPPSPRGHKWEKNLALSRELDVSIALTGKPSKTSPAVTALAVSRNHTKLLVGDERGRIFCWSADG", "length": 3184 }, "evidence": [ { "id": "A0A8V0Z5Y1", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "antigen processing and presentation", "id": "GO:0019882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1192, "end_pos": 1194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1690, "end_pos": 1692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1976, "end_pos": 1978, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2070, "end_pos": 2072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2199, "end_pos": 2201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2338, "end_pos": 2340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2601, "end_pos": 2603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2699, "end_pos": 2701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2908, "end_pos": 2910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2930, "end_pos": 2932, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3039, "end_pos": 3041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3040, "end_pos": 3042, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3067, "end_pos": 3069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3171, "end_pos": 3173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" }, { "start_pos": 987, "end_pos": 989, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1" }, { "id": "PS50197", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50197" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEACH", "eco_id": "ECO_0000259", "start_pos": 2542, "end_pos": 2836, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z5Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y1" }, { "id": "PS51783", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51783" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEACH-type PH", "eco_id": "ECO_0000259", "start_pos": 2400, "end_pos": 2525, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2123 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 1192, "end_pos": 1194 }, { "start_pos": 1421, "end_pos": 1423 }, { "start_pos": 1690, "end_pos": 1692 }, { "start_pos": 1976, "end_pos": 1978 }, { "start_pos": 2070, "end_pos": 2072 }, { "start_pos": 2199, "end_pos": 2201 }, { "start_pos": 2338, "end_pos": 2340 }, { "start_pos": 2601, "end_pos": 2603 }, { "start_pos": 2699, "end_pos": 2701 }, { "start_pos": 2908, "end_pos": 2910 }, { "start_pos": 2930, "end_pos": 2932 }, { "start_pos": 3039, "end_pos": 3041 }, { "start_pos": 3040, "end_pos": 3042 }, { "start_pos": 3067, "end_pos": 3069 }, { "start_pos": 3171, "end_pos": 3173 }, { "start_pos": 916, "end_pos": 918 }, { "start_pos": 961, "end_pos": 963 }, { "start_pos": 987, "end_pos": 989 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5Y4-1", "uniprot_ac": "A0A8V0Z5Y4", "uniprot_id": "A0A8V0Z5Y4_CHICK", "mass": { "chemical_mass": 72911.0, "monoisotopic_mass": 72911.0 }, "refseq": { "ac": "XP_004947475", "name": "amiloride-sensitive sodium channel subunit delta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947475" }, "gene_names": [ { "name": "SCNN1D", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ] }, { "name": "SCNN1D", "type": "synonym", "evidence": [ { "id": "XP_004947475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947475" } ] } ], "protein_names": [ { "name": "Sodium channel epithelial 1 subunit delta", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4/entry#names_and_taxonomy" } ] }, { "name": "amiloride-sensitive sodium channel subunit delta", "type": "synonym", "evidence": [ { "id": "XP_004947475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947475" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947475.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947475" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCNN1D", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4", "locus": { "chromosome": "21", "start_pos": 2443596, "end_pos": 2455364, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018450", "url": "https://www.ensembl.org/id/ENSGALG00010018450" } ] } } ], "crossref": [ { "id": "A0A8V0Z5Y4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "428184", "url": "https://www.ncbi.nlm.nih.gov/gene/428184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428184", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428184", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPEASHM", "url": "https://omabrowser.org/oma/group/KPEASHM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Y4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9730628", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9730628", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004947475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947475", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQEAAREEEERKEGLIEFYDSFKDMFEFFCKNTTIHGTIRLVCSSSNKMKTAFWTLLLLASFGMLYWQFALMFSQYWDYPVVLTMSMHSEPKMFPAITICNLDPYRFDLVSEHLAQLDRMAEKSVTVLYGINTSASLFHVNEKSIHVRDLPSTGNHNGSSFKLSQKFSLLRTTEFNNRTGKRQSLVGFRLCNATGGNCFYKTYSSGMDAILEWYRFHYMNIMSQQPVIINISDHEEKIEDMVYSCQYDGEPCRPSDYVHFHHPVFGSCYTFNSKGTDPFWTATKPGIPYGLSLILRAEQKDHIPLLSTVAGVKVMIHNHNQTPFLEHEGFDIRPGIATTIGIQQDKVNRLGGNYGKCTTDGSDVKVKLLYNSYTLQACLHSCFQHIMVQKCGCGYYYYPLPPGAEYCNYNKQPAWGHCFYQLYSRLRNHHLNCFDQCPKPCRESLYKVSAGTAKWPSRKSQDWIRQALRHQNGYNSTSNRKDIAKVTIYYRQLNYQSVNESPLLSDNLLLSSMGSQWSLWFGSSVLSVVEMLELLIDTLVLCLLFCYQRFRSKTLNVARTPSIPSVSLTLESYRVVQEAGNGTAPAHGHTSGVPMAVANSSDPHPAQLSSKAIPEHCPDVVLNGFRYMKDSSLGGEINH", "length": 640, "header": "tr|A0A8V0Z5Y4-1|A0A8V0Z5Y4_CHICK Isoform 1 of Sodium channel epithelial 1 subunit delta OS=Gallus gallus OX=9031 GN=SCNN1D PE=4 SV=1 CANONICAL=A0A8V0Z5Y4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4/entry#A0A8V0Z5Y4-1", "sequence": { "sequence": "MEQEAAREEEERKEGLIEFYDSFKDMFEFFCKNTTIHGTIRLVCSSSNKMKTAFWTLLLLASFGMLYWQFALMFSQYWDYPVVLTMSMHSEPKMFPAITICNLDPYRFDLVSEHLAQLDRMAEKSVTVLYGINTSASLFHVNEKSIHVRDLPSTGNHNGSSFKLSQKFSLLRTTEFNNRTGKRQSLVGFRLCNATGGNCFYKTYSSGMDAILEWYRFHYMNIMSQQPVIINISDHEEKIEDMVYSCQYDGEPCRPSDYVHFHHPVFGSCYTFNSKGTDPFWTATKPGIPYGLSLILRAEQKDHIPLLSTVAGVKVMIHNHNQTPFLEHEGFDIRPGIATTIGIQQDKVNRLGGNYGKCTTDGSDVKVKLLYNSYTLQACLHSCFQHIMVQKCGCGYYYYPLPPGAEYCNYNKQPAWGHCFYQLYSRLRNHHLNCFDQCPKPCRESLYKVSAGTAKWPSRKSQDWIRQALRHQNGYNSTSNRKDIAKVTIYYRQLNYQSVNESPLLSDNLLLSSMGSQWSLWFGSSVLSVVEMLELLIDTLVLCLLFCYQRFRSKTLNVARTPSIPSVSLTLESYRVVQEAGNGTAPAHGHTSGVPMAVANSSDPHPAQLSSKAIPEHCPDVVLNGFRYMKDSSLGGEINH", "length": 640, "header": "tr|A0A8V0Z5Y4-1|A0A8V0Z5Y4_CHICK Isoform 1 of Sodium channel epithelial 1 subunit delta OS=Gallus gallus OX=9031 GN=SCNN1D PE=4 SV=1 CANONICAL=A0A8V0Z5Y4-1" }, "locus": { "chromosome": "21", "start_pos": 2449205, "end_pos": 2444133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044612.1", "url": "https://www.ensembl.org/id/ENSGALT00010044612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026560.1", "url": "https://www.ensembl.org/id/ENSGALP00010026560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428184", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428184", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-GGA-9730628", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9730628", "resource": "Reactome", "description": "Sensory perception of salty taste" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BBK2-1", "protein_name": "Sodium channel epithelial 1 subunit delta", "gene_name": "SCNN1D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRLWSMSRLGYATSGWGTRLGMEVLQLCGGQGAGGGQTGALLRLISPTQAGASAQAAGGGPGAGRCPQPLPLPPSEEERREGLVELHTSFRELVTFFCTNATIHGTIRLVCSSQNRLKTATWALLLAGALSALYWQFGLLFQQYWRYPVVMAVSVHSERKLFPSVTLCDMNPHRPRPARRHLRALDDFARENIYSLYGFNFTESEEDPGAEALGSEPAFQLDRGIRLQRLSPLGGQNRVGFRLCNRTGGDCVHRAYSSGVTAAQEWYRFHYVNILALLPNAPEDSHRSHGGHLVSSCRYDGQDCQAGHFQTSHHPTYGSCYTFHGIWAAQHPGITHGISLVLRAELQDHLPLLFTEAGIKVLIHRHDQTPFLEHQGFSIRPGTETTIGIREDEVHRLGSPYGHCTHSAGSVDVRLLYKASYTKQACLVSCFQQLMVDTCSCGYYLYPLPAGAEYCSYTRHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESTYKLTAGVSRWPSSKSADWIPAVLDRPGGRQSPSPRSRLAKVNIFYRELNYRTVDEMPVYSVPQLLSAMGSLWSLWFGSSVLSVLEVLELLLDAMVLTLLLCCRQLHRARGQLGAAPGEPTPSQRPTCCPAAAGMTSNARGPSWPRFP", "length": 641 }, "evidence": [ { "id": "A0A8V0Z5Y4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P51172-3", "protein_name": "Epithelial sodium channel subunit delta", "gene_name": "SCNN1D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAVLSQKTTPLPRYLWPGHLSGPRRLTWSWCSDHRTPTCRELGSPHPTPCTGPARGWPRRGGGPCGFTSAGHVLCGYPLCLLSGPIQGCGTGLGDSSMAFLSRTSPVAAASFQSRQEARGSILLQSCQLPPQWLSTEAWTGEWKQPHGGALTSRSPGPVAPQRPCHLKGWQHRPTQHNAACKQGQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLTFFCTNATIHGAIRLVCSRGNRLKTTSWGLLSLGALVALCWQLGLLFERHWHRPVLMAVSVHSERKLLPLVTLCDGNPRRPSPVLRHLELLDEFARENIDSLYNVNLSKGRAALSATVPRHEPPFHLDREIRLQRLSHSGSRVRVGFRLCNSTGGDCFYRGYTSGVAAVQDWYHFHYVDILALLPAAWEDSHGSQDGHFVLSCSYDGLDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHLPLLSTLAGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLLELLELLLDASALTLVLGGRRLRRAWFSWPRASPASGASSIKPEASQMPPPAGGTSDDPEPSGPHLPRVMLPGVLAGVSAEESWAGPQPLETLDT", "length": 802 }, "evidence": [ { "id": "A0A8V0Z5Y4", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" }, { "name": "sodium channel complex", "id": "GO:0034706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z5Y9-1", "uniprot_ac": "A0A8V0Z5Y9", "uniprot_id": "A0A8V0Z5Y9_CHICK", "mass": { "chemical_mass": 35406.0, "monoisotopic_mass": 35406.0 }, "refseq": { "ac": "NP_001186337", "name": "thioredoxin-related transmembrane protein 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" }, "gene_names": [ { "name": "TMX4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z5Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ] }, { "name": "TMX4", "type": "synonym", "evidence": [ { "id": "NP_001186337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" } ] }, { "name": "TXNDC13", "type": "synonym", "evidence": [ { "id": "NP_001186337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" } ] } ], "protein_names": [ { "name": "Thioredoxin related transmembrane protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z5Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9/entry#names_and_taxonomy" } ] }, { "name": "thioredoxin domain containing 13", "type": "synonym", "evidence": [ { "id": "NP_001186337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" } ] }, { "name": "thioredoxin-related transmembrane protein 4 precursor", "type": "synonym", "evidence": [ { "id": "NP_001186337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.19725.1, SRR13267659.299986.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Dec 9, 2010 this sequence version replaced XP_415026.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9", "locus": { "chromosome": "3", "start_pos": 14344244, "end_pos": 14318483, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018453", "url": "https://www.ensembl.org/id/ENSGALG00010018453" } ] } } ], "crossref": [ { "id": "A0A8V0Z5Y9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z5Y9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416729", "url": "https://www.ncbi.nlm.nih.gov/gene/416729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416729", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416729", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGSNWSL", "url": "https://omabrowser.org/oma/group/CGSNWSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Y9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46107:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46107:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSGGVALLLGAVLGPFAASVFSSSPVGRPGEPRSRVQVLSGSNWSLVLQGQWMVEFYAPWCPACQQIELIWESFAKESEHLDITVGKVDVTQEPGLSGRFFVTTLPTIYHANDGVFRRYRGSRTLEDLQSYVLEKKWEAVEPVAGWKSPSSIVMHGMAGLFHLSGYIRQIHSYLTDTLGIHVWISYAVFILATLLIGLFLGLMLVLISDCLCPSKSNYRNETSEVITKENVENAENAVLEEPEEATELSADDAEEAAEVKDLSEGEDAPNSSVDDSEEDLALGKESGEEEEMEDLNEQPLADSETESSVRQRRSQVADGGL", "length": 323, "header": "tr|A0A8V0Z5Y9-1|A0A8V0Z5Y9_CHICK Isoform 1 of Thioredoxin related transmembrane protein 4 OS=Gallus gallus OX=9031 GN=TMX4 PE=1 SV=1 CANONICAL=A0A8V0Z5Y9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9/entry#A0A8V0Z5Y9-1", "sequence": { "sequence": "MAVSGGVALLLGAVLGPFAASVFSSSPVGRPGEPRSRVQVLSGSNWSLVLQGQWMVEFYAPWCPACQQIELIWESFAKESEHLDITVGKVDVTQEPGLSGRFFVTTLPTIYHANDGVFRRYRGSRTLEDLQSYVLEKKWEAVEPVAGWKSPSSIVMHGMAGLFHLSGYIRQIHSYLTDTLGIHVWISYAVFILATLLIGLFLGLMLVLISDCLCPSKSNYRNETSEVITKENVENAENAVLEEPEEATELSADDAEEAAEVKDLSEGEDAPNSSVDDSEEDLALGKESGEEEEMEDLNEQPLADSETESSVRQRRSQVADGGL", "length": 323, "header": "tr|A0A8V0Z5Y9-1|A0A8V0Z5Y9_CHICK Isoform 1 of Thioredoxin related transmembrane protein 4 OS=Gallus gallus OX=9031 GN=TMX4 PE=1 SV=1 CANONICAL=A0A8V0Z5Y9-1" }, "locus": { "chromosome": "3", "start_pos": 14340515, "end_pos": 14318501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044619.1", "url": "https://www.ensembl.org/id/ENSGALT00010044619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026565.1", "url": "https://www.ensembl.org/id/ENSGALP00010026565.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416729", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHB4-1", "protein_name": "Thioredoxin related transmembrane protein 4", "gene_name": "TMX4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVGGRRGTLLAALLAAWVAAAAAEAEAGSEQAAVPEERSLVRPMTASNWTLVLEGEWMLKFYAPWCPSCQQTDSEWETFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGVPAWCSYVFFIIATLIFGLFMGLVLVVISECFSMPLPRHLSERSEQSLQSEEAHTAEQLQDVEEEKDDSNEEENKDSLVDDEEEKEDLGEEDEAEEDEEDSAVTGRDEERSDALDQRPPGEAPEDEAPGGETGDNTPEQPSLAGAEVAAEDTLRQRKSQHPDKGPS", "length": 350 }, "evidence": [ { "id": "A0A8V0Z5Y9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V912-1", "protein_name": "Thioredoxin-related transmembrane protein 4", "gene_name": "Tmx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGGFCVPVFLAAWLAAAAAEAEGLEQAALPAEESRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWETFAKNGETLQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLILVVISECFYVPLPRASSERSEQEQRSEEAQGAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDDDEVEEDEEEDNLAGIMDEEKSDSNEQGVVKEGSVSPKDEEARSADTQDVVEDSLRQRKSQHAKGP", "length": 336 }, "evidence": [ { "id": "A0A8V0Z5Y9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0L0-1", "protein_name": "Thioredoxin-related transmembrane protein 4", "gene_name": "Tmx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGGFCVPVLLAAWLAAAAAEGLEQAALPAEESRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWETFAKNGETLQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLILVVISECFCVPLPRASSERCEQEQSTGEAQGAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDIGDEDEGEEDEEEDNLAGIMAEERSDTNERAVVKEGSVSPKEDGAHPADTQDVVEDALRQRKSQNANKGS", "length": 335 }, "evidence": [ { "id": "A0A8V0Z5Y9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1E5-1", "protein_name": "Thioredoxin-related transmembrane protein 4", "gene_name": "TMX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL", "length": 349 }, "evidence": [ { "id": "A0A8V0Z5Y9", "url": "https://omabrowser.org/oma/group/A0A8V0Z5Y9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "disulfide oxidoreductase activity", "id": "GO:0015036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z5Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Y9" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 140, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6L8-1", "uniprot_ac": "A0A8V0Z6L8", "uniprot_id": "A0A8V0Z6L8_CHICK", "mass": { "chemical_mass": 131267.0, "monoisotopic_mass": 131267.0 }, "refseq": {}, "gene_names": [ { "name": "RBM20", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ] } ], "protein_names": [ { "name": "RNA binding motif protein 20", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8", "locus": { "chromosome": "6", "start_pos": 26915218, "end_pos": 26825255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018455", "url": "https://www.ensembl.org/id/ENSGALG00010018455" } ] } } ], "crossref": [ { "id": "A0A8V0Z6L8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423892", "url": "https://www.ncbi.nlm.nih.gov/gene/423892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Z8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z613", "url": "https://www.orthodb.org/?gene=A0A8V0Z613", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6L3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6L8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7J6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z613", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z613", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z613-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z613-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPPSLPQLLHNAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGVRFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1183, "header": "tr|A0A8V0Z6L8-1|A0A8V0Z6L8_CHICK Isoform 1 of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#A0A8V0Z5Z8-1", "sequence": { "sequence": "MADGNMETPRAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1178, "header": "tr|A0A8V0Z5Z8-1|A0A8V0Z6L8_CHICK Computationally mapped isoform of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "locus": { "chromosome": "6", "start_pos": 26915093, "end_pos": 26854493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044633.1", "url": "https://www.ensembl.org/id/ENSGALT00010044633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026575.1", "url": "https://www.ensembl.org/id/ENSGALP00010026575.1" } ] } }, { "isoform_ac": "A0A8V0Z613-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#A0A8V0Z613-1", "sequence": { "sequence": "MLAQSTRSAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGVRFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1178, "header": "tr|A0A8V0Z613-1|A0A8V0Z613_CHICK Computationally mapped isoform of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "locus": { "chromosome": "6", "start_pos": 26915093, "end_pos": 26825460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044651.1", "url": "https://www.ensembl.org/id/ENSGALT00010044651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026590.1", "url": "https://www.ensembl.org/id/ENSGALP00010026590.1" } ] } }, { "isoform_ac": "A0A8V0Z6L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#A0A8V0Z6L3-1", "sequence": { "sequence": "MDQKSAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGVRFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1175, "header": "tr|A0A8V0Z6L3-1|A0A8V0Z6L3_CHICK Computationally mapped isoform of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "locus": { "chromosome": "6", "start_pos": 26915093, "end_pos": 26845440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044637.1", "url": "https://www.ensembl.org/id/ENSGALT00010044637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026577.1", "url": "https://www.ensembl.org/id/ENSGALP00010026577.1" } ] } }, { "isoform_ac": "A0A8V0Z6L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#A0A8V0Z6L8-1", "sequence": { "sequence": "MPPPPSLPQLLHNAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGVRFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1183, "header": "tr|A0A8V0Z6L8-1|A0A8V0Z6L8_CHICK Isoform 1 of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "locus": { "chromosome": "6", "start_pos": 26915093, "end_pos": 26825983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044642.1", "url": "https://www.ensembl.org/id/ENSGALT00010044642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026582.1", "url": "https://www.ensembl.org/id/ENSGALP00010026582.1" } ] } }, { "isoform_ac": "A0A8V0Z7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8/entry#A0A8V0Z7J6-1", "sequence": { "sequence": "MDSSAAKLLEKSPFSVSAPSPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNPAAATVLNQVLSKVAMSQPLFNQLRHPSVMGAPPGHAAGGPPPGPGITSTRFSSGGIAFPAQNAGGSLGPVQAQAPNAIVMSPFGGVMAPTSSQQPVVVGLNKVGPSAAAAAGGFYEYSKQNVTAPQAYTSEGDQSGFPSAVGARYEGPFGPAGPLKHDTPAGFQKDAYGAAPAFPGDPHTGAHPKGDPSPILHGTGTSNQWENIPNFSSQNKSDLLPSDSMWPSASQQPYEIRNELYNPEEPTPDTKFSTATAPAFGRLNNSKQSFGSPRLRQNEELSAGAPDLPMRSLQPHELNDLHGVAPLHFPHVCSLCDKKIFDLKDWDQHVKGTLHIQKCMAFSDNTGIRCVLSSTDGTLHISPNNAAIFSPSSIEDYPPNVGSSFITTSARSFGQPGATFPSLPSGFPQRKSTLGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYSEAAQAMVQYYKEKPAMINDDKLLIRMSKRYKELQLKKPGKNVAAIIQDIHSQRERDLLREADSRYGTERPRSRSPISRSLSPRSHTPSFTSCSSPRSPMGTSRTDWGNGRESWDQSPYSRREEERESREWRENGDEKRDRTDTWVHERKHYSRQLDKFDLDERIEGGRGHREKYGRSGSPGSLHPLSGYKSREDDYYRKASKSKSDKFQRQEFSGRSKRKEEAKFREHRHSYSEDAAREETAEQKHNKVSESSRQKQSDKNKVKKAEKDQEEDAVAESSDAKETKPPENKLGKEEQDPEKSSPSADKQGGESGETLENTRNEKDQDWESGSEIEGETWYPANMEELVTVDEVGEDDLIMEPDITELEEIVPVDQKSKAATEMCSCMTTMLELENDHSRLTRNEEKLTHKPLETNYRSAKGSVASSICQDDEEDDNEDAVTEASSLNLDPEQKPEESQEDRSAKEPDHQQKEVKNDKGSDTHLEPEDQHTPSVQLKEEALQFPDAFIDDYKQMGSQGAESREVMEMLVKNVSEETRHGSQECPEANSRYLEMRSLEYPEVESRRRNSPAGWEQEDVFTELSIPLGVEFVVPRTGFYCKLCGLFYTNEETAKTNHCRSTVHYKNLQKYLSQLAEESLKMKEEDSHLLQDDTGIVPHFTKKKI", "length": 1172, "header": "tr|A0A8V0Z7J6-1|A0A8V0Z7J6_CHICK Computationally mapped isoform of RNA binding motif protein 20 OS=Gallus gallus OX=9031 GN=RBM20 PE=4 SV=1 CANONICAL=A0A8V0Z6L8-1" }, "locus": { "chromosome": "6", "start_pos": 26915093, "end_pos": 26859284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044627.1", "url": "https://www.ensembl.org/id/ENSGALT00010044627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026571.1", "url": "https://www.ensembl.org/id/ENSGALP00010026571.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "splicing factor binding", "id": "GO:1990935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "negative regulation of mRNA splicing, via spliceosome", "id": "GO:0048025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "heart formation", "id": "GO:0060914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" }, { "name": "spliceosome-depend formation of circular RNA", "id": "GO:0160091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" }, { "id": "PS50171", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Matrin-type", "eco_id": "ECO_0000259", "start_pos": 1117, "end_pos": 1148, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6L8" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 477, "end_pos": 552, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 306 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 323, "end_pos": 325 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z624-1", "uniprot_ac": "A0A8V0Z624", "uniprot_id": "A0A8V0Z624_CHICK", "mass": { "chemical_mass": 58582.0, "monoisotopic_mass": 58582.0 }, "refseq": {}, "gene_names": [ { "name": "TCTE1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624" } ] } ], "protein_names": [ { "name": "T-complex-associated-testis-expressed 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z624", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCTE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624", "locus": { "chromosome": "3", "start_pos": 29923151, "end_pos": 29913760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018363", "url": "https://www.ensembl.org/id/ENSGALG00010018363" } ] } } ], "crossref": [ { "id": "A0A8V0Z624", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z624", "database": "AlphaFoldDB", "categories": [] }, { "id": "421437", "url": "https://www.ncbi.nlm.nih.gov/gene/421437", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421437", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421437", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVCHVAR", "url": "https://omabrowser.org/oma/group/PVCHVAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z624", "url": "https://www.orthodb.org/?gene=A0A8V0Z624", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z716", "url": "https://www.orthodb.org/?gene=A0A8V0Z716", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24107:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24107:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z624", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z624-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z716", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z716", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z716-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z716-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQAVGDGGRAVPSLRASQSRLMADSFCVHRIIEDPEWCLIAVPPLTELCLQHIVQNFTNNPVLDRLPPEDQRKVLARLPTGLPLTVTANLISDEGYWKRCCTERWQVCDISNHGGSWKRMFLERHLENILKCFVPNTTDPDRVLELIPLCRDYVRKLEVDQFLPPVKEDEKEETDDLSDSGSDLGFGEVYIHHYDLGALVPALPLLEELHLTYGVKDCGMNFEWNLFNFTYQDCCNLAAAVKMCHNLKVFKLTRSNVDDDRTRLLVRSLLDHPSLVELDLSHNLIGDKGAQAVSKLLNHSKLEILHLCNNQIRDEGAQALAQALAKNCTLTSLNLRLNHVEDKGGEAMGCALLTNTTLKSLHLGGNRLAEPTAVLFSQVLTQNSTLTCINFSCNPIGPDSLCSFCCTQPRLPAPPNHHPKHAPGLCASCELLGHHKRPAAYYRQCARLQTVDELVTIKAPTADSTSSFSKCDADIAGGSPVTFRLGYRRKQHQLQAPMQAGSIPLSMGHVWVCARLMGGWEEEAGE", "length": 527, "header": "tr|A0A8V0Z624-1|A0A8V0Z624_CHICK Isoform 1 of T-complex-associated-testis-expressed 1 OS=Gallus gallus OX=9031 GN=TCTE1 PE=4 SV=1 CANONICAL=A0A8V0Z624-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z624-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624/entry#A0A8V0Z624-1", "sequence": { "sequence": "MQQAVGDGGRAVPSLRASQSRLMADSFCVHRIIEDPEWCLIAVPPLTELCLQHIVQNFTNNPVLDRLPPEDQRKVLARLPTGLPLTVTANLISDEGYWKRCCTERWQVCDISNHGGSWKRMFLERHLENILKCFVPNTTDPDRVLELIPLCRDYVRKLEVDQFLPPVKEDEKEETDDLSDSGSDLGFGEVYIHHYDLGALVPALPLLEELHLTYGVKDCGMNFEWNLFNFTYQDCCNLAAAVKMCHNLKVFKLTRSNVDDDRTRLLVRSLLDHPSLVELDLSHNLIGDKGAQAVSKLLNHSKLEILHLCNNQIRDEGAQALAQALAKNCTLTSLNLRLNHVEDKGGEAMGCALLTNTTLKSLHLGGNRLAEPTAVLFSQVLTQNSTLTCINFSCNPIGPDSLCSFCCTQPRLPAPPNHHPKHAPGLCASCELLGHHKRPAAYYRQCARLQTVDELVTIKAPTADSTSSFSKCDADIAGGSPVTFRLGYRRKQHQLQAPMQAGSIPLSMGHVWVCARLMGGWEEEAGE", "length": 527, "header": "tr|A0A8V0Z624-1|A0A8V0Z624_CHICK Isoform 1 of T-complex-associated-testis-expressed 1 OS=Gallus gallus OX=9031 GN=TCTE1 PE=4 SV=1 CANONICAL=A0A8V0Z624-1" }, "locus": { "chromosome": "3", "start_pos": 29922147, "end_pos": 29916280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044335.1", "url": "https://www.ensembl.org/id/ENSGALT00010044335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026380.1", "url": "https://www.ensembl.org/id/ENSGALP00010026380.1" } ] } }, { "isoform_ac": "A0A8V0Z716-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624/entry#A0A8V0Z716-1", "sequence": { "sequence": "MQQAVGDGGRAVPSLRASQSRLMADSFCVHRIIEDPEWCLIAVPPLTELCLQHIVQNFTNNPVLDRLPPEDQRKVLARLPTGLPLTVTANLISDEGYWKRCCTERWQVCDISNHGGSWKRMFLERHLENILKCFVPNTTDPDRVLELIPLCRDYVRKLEVDQFLPPVKEDEKEETDDLSDSGSDLGFGEVYIHHYDLGALVPALPLLEELHLTYGVKDCGMNFEWNLFNFTYQDCCNLAAAVKMCHNLKVFKLTRSNVDDDRTRLLVRSLLDHPSLVELDLSHNLIGDKGAQAVSKLLNHSKLEILHLCNNQIRDEGAQALAQALAKNCTLTSLNLRLNHVEDKGGEAMGCALLTNTTLKSLHLGGNRLAEPTAVLFSQVLTQNSTLTCINFSCNPIGPDGGKQLLEGLRCNQTMTEFDLRLAEVGEESEYLISQMLWANRDAARLQPVLQQPAEPL", "length": 457, "header": "tr|A0A8V0Z716-1|A0A8V0Z716_CHICK Computationally mapped isoform of T-complex-associated-testis-expressed 1 OS=Gallus gallus OX=9031 GN=TCTE1 PE=4 SV=1 CANONICAL=A0A8V0Z624-1" }, "locus": { "chromosome": "3", "start_pos": 29920707, "end_pos": 29916280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044333.1", "url": "https://www.ensembl.org/id/ENSGALT00010044333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026379.1", "url": "https://www.ensembl.org/id/ENSGALP00010026379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421437", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ART2-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "Drc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQETSTTASDPSSRSQSAFNIQRQVSTLGSTSPGPVSLKTSTSPAPSQLKTKTTNVRRMRRIISEDPEWSLAIVPLLTELCIQHIVKNFQNNPILKQLLPEHQKKVLSSLPPELPLSVTANLIEDENYWHRCCIKRWSVCHVSKHGDSWKRMFFERHLENLLKLFIPGTTDPNVILDLVPLCRNYVRRIHVDQFLPPVRMPTPPQGEEQSDSGSEGEGNEPEKNHYQLQALVGGLKYLEELDLVYGVKDCGMNFEWNLFLFTYRDCHSLAATIKACHTLKIFRLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLNLANNQLRASGAQSLAHALAHNTNLVSLNLRLNCIEDEGGQAIAHALETNKCLTVLNLGGNELSEPTATLLSQVLPVNTTLISLNLSCNHIGQDGGKQLLEGMSDNKTILEFDLRLSDVAQESEYLIGQVLHNNREAARQRTLSPGHLTLPTNNYSENSVG", "length": 498 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6H639-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "Drc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQETPSVPSNSSSHSQSVLTIQRQVSALGSSSTGPTSLKTSSTPTPGQLKTKVPNVRRMRRIISEDAEWSLAIVPLLTELCIQHIVKNFQNNPILKQLPLEHQKKVLSNLPPELPLTVTANLIDDENYWHRCCIKRWSVCHVSRHGGSWKRMFFERHLENLLKLFIPGTTDPNVILDLLPLCRNYVRRIHVDQFLPPVRMPTPLQGEEQSDSGSEGEGSEPEKDHYQLQTLVGGLKHLEELDLVYGVKDCGMNFEWNLFLFTYRDCYSLAATIKACHTLKIFKLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLNLANNQLQAPGAQSLAHALAHNTNLVFLNLRLNCIEDEGGQAIAHALETNKCLSVLHLGGNKLSEPTATLLSQMLTVNTTLVSLNLSCNHIGQDGGKQLLEGISDNKTILEFDLRLSDVSQESEYLIGQVLHANREAARQRTLNPGHFSSPTNNCTENSVV", "length": 498 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1RQT8-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "TCTE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQETQTTPSLSIPSRSSTSTQDRSSTTGQASSTGPQPSKPPTIAPPVKPKGPSSGAGVHRMRRIIAEDTEWSLAIVPLLTELCIQHIVKNFQNNPILKQLLPEHQKKVLSHLPPDLPLAVTANLIDDENYWRRCCMQRWPVCHVDEHGGSWKRMFFELHLENLLKHFIPSTTDPEVILSLLPLCRNYVRTIRVDQFLPPVQLPSPPHGGDQSDSGSEGEMEEPAMDHYQLRDLVAGLDHLEELDLVYGVKDCGMNFEWNLFLFTYRDCHSLAATIKACHTLKVFRLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLSLANNQVRAPGAQSLAHALAHNTNLLSLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTASLLSQVLSINTTLTSINLTGNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDIAQESEYLISQALCANREAARQQALNPSHFMSPITAKGPENPAG", "length": 501 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HC80-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "Tcte1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHDPPATSSHPGSRTSMYNVQRQHSGLGGVSSATQAAKTSPSHAPGHLKSKIPSNRRMRRIISEDAEWTLAIVPLLTELCIQHIVKNFQNNPILKQLLPQHQQKVLSHLPPDLPLTVTANLIDDENYWHRCCIKRWPVCHVAKHGGSWKRMFFERHLENLLKLFIPGTTDPNVILDLLPLCRNYVRRIQVDQFLPPVRLPTPPQGDEQSDSGSDGEGNEPEKDHYQLEALVAGLKHLEELDLVYGVKDCGMNFEWNLFLFTFRDCHSLAATIKACHTLKIFRLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLNLANNQLRAPGAQSLAHALAHNTNLVSLNLRLNCIEDEGGQAIAHALETNKCLTTLHLGGNELSEPTATVLSQVLPINTILTSLNLSCNHIGVDGGKQLLEGMSENKTILEFDLRLSDVSQESEYLIGQALHANREAARQRALNPGHFMTPITNNGPENSVA", "length": 498 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5JU00-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "DRC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQDTVTTSALLDPSHSSVSTQDNSSTGGHTSSTSPQLSKPSITPVPAKSRNPHPRANIRRMRRIIAEDPEWSLAIVPLLTELCIQHIIRNFQKNPILKQMLPEHQQKVLNHLSPDLPLAVTANLIDSENYWLRCCMHRWPVCHVAHHGGSWKRMFFERHLENLLKHFIPGTTDPAVILDLLPLCRNYVRRVHVDQFLPPVQLPAQLRPGDQSDSGSEGEMEEPTVDHYQLGDLVAGLSHLEELDLVYDVKDCGMNFEWNLFLFTYRDCLSLAAAIKACHTLKIFKLTRSKVDDDKARIIIRSLLDHPVLEELDLSQNLIGDRGARGAAKLLSHSRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQESEYLIGQALYANREAARQRALNPSHFMSTITANGPENSVG", "length": 501 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEH4-1", "protein_name": "Dynein regulatory complex subunit 5", "gene_name": "Dmel\\CG14325", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFTYCEFPSTVSIDTFKAYFNLTDVKLPKVGDKSVDTIQIPSEDQEDQTNQAKSLRHLVLDSIVENWSELPLYRQLGRREDRNYLLSHLDTQLPLQLLSAHIREDFFWQRCYGHRWRSAPLQARGRERPWINIYMERHVQEFIENMPTGDYEQDGNVQVVLDICAAYINQLEISFLQPAPPTTDANDHIPLDYLLSNLPDLRQLRLSYSTKTVGCNYQMGCNQLTVRDILHLTKGLSQCHELRTFCLHNTKLMPYQLRFLAHSLDKGCHHLTEMSLLHCAVGDAGIRCFLETCGKESFGTLTVLDLTNNKITEEGAYILSRTLRHVPLEKLVLRLNPIQSDGAAAIFNTLQVMPIKELDLGTCGITETITKLFMMLICQHTSLLEIDLSNNSLGEDFGKHLMKIISCNKLLERLDLRNTGLSLDMRRKFQEFLLKNVDRKKHEALKQKQRDKFKAMMQL", "length": 460 }, "evidence": [ { "id": "A0A8V0Z624", "url": "https://omabrowser.org/oma/group/A0A8V0Z624/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z624", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z624" } ], "pmid": "" }, { "name": "sperm 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420888.1. 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{ "id": "PTHR23235:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420888", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420888", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z644", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z644", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z644-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z644-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNVMDFSCSDPLYSKYEESCEMKAGDLQGLGQPEQQLLEEAEFLGGELLEYPPPGSQLSPSLSYTGSFFIKAVPEHPQDQESLFNLMSGILGISPFATSEGHQRHLDALYPCPEVAPNQMDLYTSCQPEMNGSMQTPFAEQSYGSFPSADAVHPLQPQPSLGTTSQCFFESKLLDSKQDIKLPSSSTALDKFKAPCAQWEPITPHQPFLPTGFHPTETFPAGESSQAMFHPLGSKMENALTISCQAELGSLTEDPGCFPSTNLGFGCEPENFADTKIHNLPAQLMPEFESSLAQPEVLPGLMGPTEILHPHPSPSVPPTDFLGHPVPSSVPSLLPTPPTLAEPKKKTRRTKCSSKCFCPKPHEKAFACPVENCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDTCGRRFARSDEKKRHSKVHLKQKARTEEKLKGLGFFSVGLSFGTL", "length": 473, "header": "tr|A0A8V0Z644-1|A0A8V0Z644_CHICK Isoform 1 of Early growth response 4 OS=Gallus gallus OX=9031 GN=EGR4 PE=3 SV=1 CANONICAL=A0A8V0Z644-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z644-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z644/entry#A0A8V0Z644-1", "sequence": { "sequence": "MLNVMDFSCSDPLYSKYEESCEMKAGDLQGLGQPEQQLLEEAEFLGGELLEYPPPGSQLSPSLSYTGSFFIKAVPEHPQDQESLFNLMSGILGISPFATSEGHQRHLDALYPCPEVAPNQMDLYTSCQPEMNGSMQTPFAEQSYGSFPSADAVHPLQPQPSLGTTSQCFFESKLLDSKQDIKLPSSSTALDKFKAPCAQWEPITPHQPFLPTGFHPTETFPAGESSQAMFHPLGSKMENALTISCQAELGSLTEDPGCFPSTNLGFGCEPENFADTKIHNLPAQLMPEFESSLAQPEVLPGLMGPTEILHPHPSPSVPPTDFLGHPVPSSVPSLLPTPPTLAEPKKKTRRTKCSSKCFCPKPHEKAFACPVENCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDTCGRRFARSDEKKRHSKVHLKQKARTEEKLKGLGFFSVGLSFGTL", "length": 473, "header": "tr|A0A8V0Z644-1|A0A8V0Z644_CHICK Isoform 1 of Early growth response 4 OS=Gallus gallus OX=9031 GN=EGR4 PE=3 SV=1 CANONICAL=A0A8V0Z644-1" }, "locus": { "chromosome": "4", "start_pos": 89265243, "end_pos": 89263547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043742.1", "url": "https://www.ensembl.org/id/ENSGALT00010043742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026024.1", "url": "https://www.ensembl.org/id/ENSGALP00010026024.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422950", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q00911-1", "protein_name": "Early growth response protein 4", "gene_name": "Egr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHLSDFSGPDALLSKPTEGCAHTSPELPRLPARDAPSAAAYPGGDFLSWALSTCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPSPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGAPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPASRLYPPGAYDAFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAVPQAQLSPLGLRGAATADFSKALVADLPGGSGVAAPSSPATSFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRTFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL", "length": 478 }, "evidence": [ { "id": "A0A8V0Z644", "url": "https://omabrowser.org/oma/group/A0A8V0Z644/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05215-1", "protein_name": "Early growth response protein 4", "gene_name": "EGR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVARGVGSPEPAPPQLYKWGGCGLGEPGSALERRGAAARGRCGRARAPRLPDSFPRGECPKPGARAPRSVRCGEPLPPASPPPARPQAQRARPRAPHSRRRAMLHLSEFSEPDALLVKSTEGCCAEPSAELPRLPARDAPAATGYPGAGDFLSWALNSCGASGDLADSCFLEGPAPTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDAVSAFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKIEDLLSISCPAELPAVPANRLYPSGAYDAFPLAPGDLGEGAEGLPGLLTPPSGEGGSSGDGGEFLASTQPQLSPLGLRSAAAADFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCPRPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFASL", "length": 589 }, "evidence": [ { "id": "A0A8V0Z644", "url": "https://omabrowser.org/oma/group/A0A8V0Z644/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUF2-1", "protein_name": "Early growth response protein 4", "gene_name": "Egr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLHLSDFSGSDALLSKPTEGCAHASPELPRLPARDAPSAAAYPGGDFLSWALSSCGAGGDLTDSCFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDVPFPAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAASAFKGPYAPWELLSAGVPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPAARLYQAGAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFSKPLVADLPGGSGVAAPSSPAASFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFAAL", "length": 478 }, "evidence": [ { "id": "A0A8V0Z644", "url": "https://omabrowser.org/oma/group/A0A8V0Z644/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, 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{ "uniprot_canonical_ac": "A0A8V0Z656-1", "uniprot_ac": "A0A8V0Z656", "uniprot_id": "A0A8V0Z656_CHICK", "mass": { "chemical_mass": 88562.0, "monoisotopic_mass": 88562.0 }, "refseq": { "ac": "XP_004936346", "name": "F-box only protein 41", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936346" }, "gene_names": [ { "name": "FBXO41", "type": "recommended", "evidence": [ { "id": "A0A8V0Z656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656" } ] }, { "name": "FBXO41", "type": "synonym", "evidence": [ { "id": "XP_004936346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936346" } ] } ], "protein_names": [ { "name": "F-box only protein 41", "type": "recommended", "evidence": [ { "id": "A0A8V0Z656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 41", "type": "synonym", "evidence": [ { "id": "XP_004936346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936346" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z656", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656", "locus": { "chromosome": "4", "start_pos": 89282254, "end_pos": 89270918, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018124", "url": "https://www.ensembl.org/id/ENSGALG00010018124" } ] } } ], "crossref": [ { "id": "A0A8V0Z656", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z656", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22109", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22109", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428805", "url": "https://www.ncbi.nlm.nih.gov/gene/428805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428805", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGTTPNC", "url": "https://omabrowser.org/oma/group/CGTTPNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z656", "url": "https://www.orthodb.org/?gene=A0A8V0Z656", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC17", "url": "https://www.orthodb.org/?gene=A0A8V0ZC17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15739:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15739:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z656", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z656-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYNHTYETLYVLSKTNSICDAAVFPLAADGALLTPAARRDYFESTSFQGKEQRFSCDLVPAEELEPAPSSSPSPRYVHEIEIPLTEIFTRGKAVAPAPTPPAAMDAAYEEGLARLKIRAFEKLEVDKRLEKLTEEVEQKIASQVGRLQVELDRKSSELEKAKQESLRLSREKQELEDRASELSRQVDVSVEMLASLKQDLVQKEQELTRKQQEVLQIDQFLKETAAREANAKVRLQHFIEELLDRADRAEKQLQIISSSCGTTPNGSLGRCGTPGAKAAGRPVPTRAQRERHPGLGAAVHGPYAIPNQRSSSSTGASSRAKAVSQSSGCYDSDSAEPCPTDDTADGHPYTARDGGRGSGLRRQAIQNWHRRPYRNSTEGEEGDVSDVGSRTTESEAEGWEPEVPGIAASRPGGSCRLTARSEGAMSKGGRLERGSPGHSSEVISPEILKMRAALFCIFTYLDTKTLLRAAEVCKDWKFVARHPAVWTRVLLENARVSSKFLAMLSQWCTQMHSLTLQNLKPRQRGKKESKEDYMKSTRGCLEAGLESLLKATGSNLLILRISHCPNVLTDRSLWLASCYCRALQAVTYRSSTDPVGHEVIWALGAGCRDIISLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGIGGAGCGVQGLASLARNCMRLQVLELDHVAEINQEVAAEMCREGLKGLEMLVLTSTPVTPKALLHFNSVCRNLKSIVVQVGIVDYFKEPHSPEAKKMFEEMVNKLQALRKRPGFSKILHIKVEGGC", "length": 801, "header": "tr|A0A8V0Z656-1|A0A8V0Z656_CHICK Isoform 1 of F-box only protein 41 OS=Gallus gallus OX=9031 GN=FBXO41 PE=4 SV=1 CANONICAL=A0A8V0Z656-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z656-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656/entry#A0A8V0Z656-1", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYNHTYETLYVLSKTNSICDAAVFPLAADGALLTPAARRDYFESTSFQGKEQRFSCDLVPAEELEPAPSSSPSPRYVHEIEIPLTEIFTRGKAVAPAPTPPAAMDAAYEEGLARLKIRAFEKLEVDKRLEKLTEEVEQKIASQVGRLQVELDRKSSELEKAKQESLRLSREKQELEDRASELSRQVDVSVEMLASLKQDLVQKEQELTRKQQEVLQIDQFLKETAAREANAKVRLQHFIEELLDRADRAEKQLQIISSSCGTTPNGSLGRCGTPGAKAAGRPVPTRAQRERHPGLGAAVHGPYAIPNQRSSSSTGASSRAKAVSQSSGCYDSDSAEPCPTDDTADGHPYTARDGGRGSGLRRQAIQNWHRRPYRNSTEGEEGDVSDVGSRTTESEAEGWEPEVPGIAASRPGGSCRLTARSEGAMSKGGRLERGSPGHSSEVISPEILKMRAALFCIFTYLDTKTLLRAAEVCKDWKFVARHPAVWTRVLLENARVSSKFLAMLSQWCTQMHSLTLQNLKPRQRGKKESKEDYMKSTRGCLEAGLESLLKATGSNLLILRISHCPNVLTDRSLWLASCYCRALQAVTYRSSTDPVGHEVIWALGAGCRDIISLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGIGGAGCGVQGLASLARNCMRLQVLELDHVAEINQEVAAEMCREGLKGLEMLVLTSTPVTPKALLHFNSVCRNLKSIVVQVGIVDYFKEPHSPEAKKMFEEMVNKLQALRKRPGFSKILHIKVEGGC", "length": 801, "header": "tr|A0A8V0Z656-1|A0A8V0Z656_CHICK Isoform 1 of F-box only protein 41 OS=Gallus gallus OX=9031 GN=FBXO41 PE=4 SV=1 CANONICAL=A0A8V0Z656-1" }, "locus": { "chromosome": "4", "start_pos": 89280234, "end_pos": 89271117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043784.1", "url": "https://www.ensembl.org/id/ENSGALT00010043784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026040.1", "url": "https://www.ensembl.org/id/ENSGALP00010026040.1" } ] } }, { "isoform_ac": "A0A8V0ZC17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656/entry#A0A8V0ZC17-1", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYNHTYETLYVLSKTNSICDAAVFPLAADGALLTPAARRDYFESTSFQGKEQRFSCDLVPAEELEPAPSSSPSPRYVHEIEIPLTEIFTRGKAVAPAPTPPAAMDAAYEEGLARLKIRAFEKLEKAKQESLRLSREKQELEDRASELSRQVDVSVEMLASLKQDLVQKEQELTRKQQEVLQIDQFLKETAAREANAKVRLQHFIEELLDRADRAEKQLQIISSSCGTTPNGSLGRCGTPGAKAAGRPVPTRAQRERHPGLGAAVHGPYAIPNQRSSSSTGASSRAKAVSQSSGCYDSDSAEPCPTDDTADGHPYTARDGGRGSGLRRQAIQNWHRRPYRNSTEGEEGDVSDVGSRTTESEAEGWEPEVPGIAASRPGGSCRLTARSEGAMSKGGRLERGSPGHSSEVISPEILKMRAALFCIFTYLDTKTLLRAAEVCKDWKFVARHPAVWTRVLLENARVSSKFLAMLSQWCTQMHSLTLQNLKPRQRGKKESKEDYMKSTRGCLEAGLESLLKATGSNLLILRISHCPNVLTDRSLWLASCYCRALQAVTYRSSTDPVGHEVIWALGAGCRDIISLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGIGGAGCGVQGLASLARNCMRLQVLELDHVAEINQEVAAEMCREGLKGLEMLVLTSTPVTPKALLHFNSVCRNLKSIVVQVGIVDYFKEPHSPEAKKMFEEMVNKLQALRKRPGFSKILHIKVEGGC", "length": 766, "header": "tr|A0A8V0ZC17-1|A0A8V0ZC17_CHICK Computationally mapped isoform of F-box only protein 41 OS=Gallus gallus OX=9031 GN=FBXO41 PE=4 SV=1 CANONICAL=A0A8V0Z656-1" }, "locus": { "chromosome": "4", "start_pos": 89280234, "end_pos": 89271117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043789.1", "url": "https://www.ensembl.org/id/ENSGALT00010043789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026043.1", "url": "https://www.ensembl.org/id/ENSGALP00010026043.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428805", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A8K9-1", "protein_name": "F-box only protein 41", "gene_name": "FBXO41", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDSAAAAAAAAAASGFQLAPEPAALLAVPGARREVFESTSFQGKEQATGPSPAAPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAAAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGSCSGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGAGGSGAGPGTRGPGRSREHHAGPAVPSTYAVSRHGSSPSTGASSRIPAASQSSGCYDSDSLELPRPEEGTPEDSGPGGLGTRVQAANGGSDRAQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDAPRPGPAVAGPLSSCRLSARPEGGSGRGRRAERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHVKVEGGC", "length": 874 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0M8C7-1", "protein_name": "F-box only protein 41", "gene_name": "Fbxo41", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPAPAGPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPTSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGSASGPGLRGPGRMREHHAGPAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRQEEGPSEDSGPGGLGSRAQATNGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRPGPAVAGPLNSCRLSARPEGGSGRGRRMERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "length": 873 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BK68-1", "protein_name": "F-box only protein 41", "gene_name": "FBXO41", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAFPLAPEPAALLAVPGARREVFESTSFQGKEQAVGQSSAAPHLLHHHHHHAPLAHFPGDLVPAGLPCEELAEPGLVPAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCPGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGAGAGPSTRAPGRMREHHAGPAMPSTYAVSRHGSSPSTGASSRIPAASQSSGCYDSDSLELPRPEEGAPEDSGPGGLGTRVQAANGGSERAQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSEVPRPGPAMAGPVSSCRLSARPEGGSGRGRRAERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPMRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGC", "length": 863 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6NUQ2-1", "protein_name": "F-box only protein 41", "gene_name": "fbxo41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYNHTYETLYVLSKSNSVCDAAALLPLVADGALTAESRFPYRELPCSGEELGLAPSSTACYLPNVEFPLGEILVKTAMSSSDALSSAGNNAVAVAANVAASAVEAAYEEGLARLKARAFERLELDERLEKLSEEVEQKISARVSRLQAELERKSSELEKAKLESERLSQEKQDLEDKATELSRQVDVSVEMLASLKQDLVNKEQELSHKQQEVSQIDQFLQETAAREANAKLRLQQFIEELLDRADRAEKQLQIISNCGTTPNGSLGHCSLGSKSNGRQRNSSLSGVSRGMYQVSDRRSSPSTAASVRGKSVSQGSGGYDSDSVDLHALEDCPDAQYYHVQCRLGEGGGAGYERAAASRSWGLRKQAIQNWQRRPYRNSMEGEEGDVSDVGSRTTESEAEMWEQDRRADSSQHAGHRGGYRLPTGRSEGGYKACRHEKSPSKGSEVISPEVLKMRAALFCIFTYLDTKTLLRAAEVCRDWRSVARHPAVWTRVLLENARICSKFLCTLSQWCTQTHSLILQNLKPRQRGKKETKEEYLKSTRGCLEEGLEALLKGTGSNLLILKVSHCPNLLTDRSLWLASCYCRALQAVTYRSATDPVGQEVIWALGAGCRDIISLQVAPLHPCQQPARFSNRCLQTIGRCWPHLRALGVGGAGCGIQGLASLARNCMRLQVLELDHVSEINQEVAAEMCREGLKGLEMLVLTSTPVTPKALLHFNSVCRNLKSIVVQIGIEDYFEDPNSPEARKLFDEMVNKLQALKKRPGFSKILHVKADGLC", "length": 805 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6NS60-1", "protein_name": "F-box only protein 41", "gene_name": "Fbxo41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQATGPSPAGPHLLHHHHHHAPLAHFPADLVPASLPCEELAEPGLVPAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPSSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGSASGPGVRGPGRMREHHAGSAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGPSEDSGPGGLGSRAQATNGGSERSQAPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRPGPAVAGPLNSCRLSARPEGGSGRGRRVERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "length": 873 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TF61-1", "protein_name": "F-box only protein 41", "gene_name": "FBXO41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPSPAAPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAAAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCPGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGGGAGPNARGPGRMREHHVGPAVPNTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGAPEDSGPGGLGTRAQAANGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPLDAPRPGPAMAGPLSSCRLSARPEGGSGRGRRAERVSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "length": 875 }, "evidence": [ { "id": "A0A8V0Z656", "url": "https://omabrowser.org/oma/group/A0A8V0Z656/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656" }, { "id": "PF12937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 483, "end_pos": 520, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z656" }, { "id": "PF23165", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23165" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FBX41/ZN365 C2H2-type zinc finger", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 35, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 128 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 404, "end_pos": 406 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z659-1", "uniprot_ac": "A0A8V0Z659", "uniprot_id": "A0A8V0Z659_CHICK", "mass": { "chemical_mass": 75881.0, "monoisotopic_mass": 75881.0 }, "refseq": {}, "gene_names": [ { "name": "TWNK", "type": "recommended", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ], "protein_names": [ { "name": "Twinkle mtDNA helicase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659/entry#names_and_taxonomy" } ] }, { "name": "Twinkle protein, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mitochondrial helicase involved in mtDNA replication and repair. Might have a role in mtDNA repair. Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB. Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate. Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand. In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL8#function" }, { "database": "UniProtKB", "id": "ARBA00055412", "url": "https://www.uniprot.org/uniprotkb/ARBA00055412#function" }, { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TWNK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659", "locus": { "chromosome": "6", "start_pos": 23871056, "end_pos": 23874659, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018482", "url": "https://www.ensembl.org/id/ENSGALG00010018482" } ] } } ], "crossref": [ { "id": "A0A8V0Z659", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z659", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01122", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01122", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z659", "url": "https://www.orthodb.org/?gene=A0A8V0Z659", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDL8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12873", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12873", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12873:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12873:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9913635", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z659-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVPLRPCRASGRFLPLLRGGARSRGASPWAAGPGRVAQRRYKKDVLPEPGGAAPAVSVTEIRRYLRAQGIPFQDGYSCLHAPSLFGPELPPAAGPPFTLFIDKTTGSFLCTATLAEGGWQDLQAAVELRHRGVPAPGPDEGEREEEEEAEARRAREDARRIWERALPLGELLDEEETRATKAAFGIAPLADGTLKRFGVRYLRAAKALVFPWFAPRDAALRGLKLLVAEQRGDAVSYTEETLPRFDAYRNLFGLPLIGRRDAEVVLTGSELDALALHQATGVPCLALPRGATILPPALLPYLEQFRRVTLWLGDDLRSWEASKLFARKLNPKRCSLVQPGDLQPRPLEALNRGLNLTKILRAALPAGHKAIVSFRQLREEVFGELANSEQVAGVKWARFPELNKLLKGHRRGELTVFTGPTGSGKTTFISEYALDLCTQGVCTLWGSFEINNIRLAKIMLTQFATRRLEDQLELYDEWADRFEDLPLYFMTFHGQQNIKTVLDTMQHAVYMYDITHVVVDNLQFMMGHEQLSADRLAAQDFIVGAFRKFATDNTCHITLVIHPRKEDDEKELQTASIFGSAKLAGCGGAPCPAAPPGDVLLPQASQEADNVLILQDRKLTTGPGKRYLQVSKNRFDGDVGVFPLEFSKASLTFSSYGKSKAKLKKVKEEKGPSPKKGPSGGVGGSSKP", "length": 690, "header": "tr|A0A8V0Z659-1|A0A8V0Z659_CHICK Isoform 1 of Twinkle mtDNA helicase OS=Gallus gallus OX=9031 GN=TWNK PE=4 SV=1 CANONICAL=A0A8V0Z659-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z659-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659/entry#A0A8V0Z659-1", "sequence": { "sequence": "MAAVPLRPCRASGRFLPLLRGGARSRGASPWAAGPGRVAQRRYKKDVLPEPGGAAPAVSVTEIRRYLRAQGIPFQDGYSCLHAPSLFGPELPPAAGPPFTLFIDKTTGSFLCTATLAEGGWQDLQAAVELRHRGVPAPGPDEGEREEEEEAEARRAREDARRIWERALPLGELLDEEETRATKAAFGIAPLADGTLKRFGVRYLRAAKALVFPWFAPRDAALRGLKLLVAEQRGDAVSYTEETLPRFDAYRNLFGLPLIGRRDAEVVLTGSELDALALHQATGVPCLALPRGATILPPALLPYLEQFRRVTLWLGDDLRSWEASKLFARKLNPKRCSLVQPGDLQPRPLEALNRGLNLTKILRAALPAGHKAIVSFRQLREEVFGELANSEQVAGVKWARFPELNKLLKGHRRGELTVFTGPTGSGKTTFISEYALDLCTQGVCTLWGSFEINNIRLAKIMLTQFATRRLEDQLELYDEWADRFEDLPLYFMTFHGQQNIKTVLDTMQHAVYMYDITHVVVDNLQFMMGHEQLSADRLAAQDFIVGAFRKFATDNTCHITLVIHPRKEDDEKELQTASIFGSAKLAGCGGAPCPAAPPGDVLLPQASQEADNVLILQDRKLTTGPGKRYLQVSKNRFDGDVGVFPLEFSKASLTFSSYGKSKAKLKKVKEEKGPSPKKGPSGGVGGSSKP", "length": 690, "header": "tr|A0A8V0Z659-1|A0A8V0Z659_CHICK Isoform 1 of Twinkle mtDNA helicase OS=Gallus gallus OX=9031 GN=TWNK PE=4 SV=1 CANONICAL=A0A8V0Z659-1" }, "locus": { "chromosome": "6", "start_pos": 23874567, "end_pos": 23871476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044708.1", "url": "https://www.ensembl.org/id/ENSGALT00010044708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026630.1", "url": "https://www.ensembl.org/id/ENSGALP00010026630.1" } ] } }, { "isoform_ac": "A0A8V0ZDL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659/entry#A0A8V0ZDL8-1", "sequence": { "sequence": "GRVAQRRYKKDVLPEPGGAAPAVSVTEIRRYLRAQGIPFQDGYSCLHAPSLFGPELPPAAGPPFTLFIDKTTGSFLCTATLAEGGWQDLQAAVELRHRGVPAPGPDEGEREEEEEAEARRAREDARRIWERALPLGELLDEEETRATKAAFGIAPLADGTLKRFGVRYLRAAKALVFPWFAPRDAALRGLKLLVAEQRGDAVSYTEETLPRFDAYRNLFGLPLIGRRDAEVVLTGSELDALALHQATGVPCLALPRGATILPPALLPYLEQFRRVTLWLGDDLRSWEASKLFARKLNPKRCSLVQPGDLQPRPLEALNRGLNLTKILRAALPAGHKAIVSFRQLREEVFGELANSEQVAGVKWARFPELNKLLKGHRRGELTVFTGPTGSGKTTFISEYALDLCTQGVCTLWGSFEINNIRLAKIMLTQFATRRLEDQLELYDEWADRFEDLPLYFMTFHGQQNIKTVLDTMQHAVYMYDITHVVVDNLQFMMGHEQLSADRLAAQDFIVGAFRKFATDNTCHITLVIHPRKEDDEKELQTASIFGSAKASQEADNVLILQDRKLTTGPGKRYLQVSKNRFDGDVGVFPLEFSKASLTFSSYGKSKAKLKKGPSGGVGGSSKP", "length": 623, "header": "tr|A0A8V0ZDL8-1|A0A8V0ZDL8_CHICK Computationally mapped isoform of Twinkle mtDNA helicase OS=Gallus gallus OX=9031 GN=TWNK PE=4 SV=1 CANONICAL=A0A8V0Z659-1" }, "locus": { "chromosome": "6", "start_pos": 23874462, "end_pos": 23871476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044712.1", "url": "https://www.ensembl.org/id/ENSGALT00010044712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026634.1", "url": "https://www.ensembl.org/id/ENSGALP00010026634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-GGA-9913635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913635", "resource": "Reactome", "description": "Strand-asynchronous mitochondrial DNA replication" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "mitochondrial chromosome", "id": "GO:0000262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "protein hexamerization", "id": "GO:0034214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" }, { "name": "mitochondrial transcription", "id": "GO:0006390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006390", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z659", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-GGA-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XE68-1", "A0A8V0XIM8-1", "A0A8V1ABW8-1", "A0A8V0YYX3-1", "A0A1D5NYJ2-1", "A0A8V0XA67-1", "A0A1D5NT61-1", "A0A1D5P1U2-1", "Q5ZKA2-1", "A0A8V0Y2T0-1", "F1NNW2-1", "A0A8V0ZX51-1", "A0A8V1A234-1", "A0A8V1A624-1", "A0A8V0YK11-1", "A0A8V0YUH5-1", "E1BVT3-1", "A0A8V0Z707-1", "A0A8V0ZBW4-1", "A0A8V0X2T8-1", "F1NLP2-1", "Q5ZL72-1", "A0A8V0Y005-1", "A0A8V0Y318-1", "A0A8V0Y9B0-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9838081" } ] }, { "id": "R-GGA-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XE68-1", "A0A8V0XIM8-1", "A0A8V1ABW8-1", "A0A8V0YYX3-1", "A0A1D5NYJ2-1", "A0A8V0XA67-1", "A0A1D5NT61-1", "A0A1D5P1U2-1", "Q5ZKA2-1", "A0A8V0Y2T0-1", "F1NNW2-1", "A0A8V0ZX51-1", "A0A8V1A234-1", "A0A8V1A624-1", "A0A8V0YK11-1", "A0A8V0YUH5-1", "E1BVT3-1", "A0A8V0Z707-1", "A0A8V0ZBW4-1", "A0A8V0X2T8-1", "F1NLP2-1", "Q5ZL72-1", "A0A8V0Y005-1", "A0A8V0Y318-1", "A0A8V0Y9B0-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9838093" } ] }, { "id": "R-GGA-9914364", "name": "POLG in the replisome polymerizes the H strand", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914364", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914364" } ] }, { "id": "R-GGA-9914404", "name": "POLRMT and POLG bind the mitochondrial L strand replication origin (OriL)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BZ13-1", "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914404", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914404" } ] }, { "id": "R-GGA-9914409", "name": "POLRMT polymerizes RNA primer for mitochondrial L strand replication", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113573", "R-ALL-110731" ], "output_participant_list": [ "R-GGA-163267" ], "enzyme_list": [ "E1BZ13-1", "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914409", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914409" } ] }, { "id": "R-GGA-9914438", "name": "TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914438", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914438" } ] }, { "id": "R-GGA-9914478", "name": "SSBP1 binds the displaced parental H strand", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914478", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914478" } ] }, { "id": "R-GGA-9914498", "name": "POLG in the replisome polymerizes the L strand", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-110653", "R-ALL-110669", "R-ALL-110681", "R-ALL-110719" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z1D7-1", "A0A8V0Z659-1" ], "evidence": [ { "id": "R-GGA-9914498", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9914498" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110653", "participant_name": "dATP [mitochondrial matrix]", "crossref": [ { "id": "61404", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215662", "database": "ZINC", "url": "" }, { "id": "C00131", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-110669", "participant_name": "dCTP [mitochondrial matrix]", "crossref": [ { "id": "61481", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215945", "database": "ZINC", "url": "" }, { "id": "C00458", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-110681", "participant_name": "dGTP [mitochondrial matrix]", "crossref": [ { "id": "61429", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215755", "database": "ZINC", "url": "" }, { "id": "C00286", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-110719", "participant_name": "dTTP [mitochondrial matrix]", "crossref": [ { "id": "37568", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215959", "database": "ZINC", "url": "" }, { "id": "C00459", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-110731", "participant_name": "UTP [mitochondrial matrix]", "crossref": [ { "id": "46398", "database": "ChEBI", "url": "" }, { "id": "ZINC000003861755", "database": "ZINC", "url": "" }, { "id": "C00075", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-113573", "participant_name": "GTP [mitochondrial matrix]", "crossref": [ { "id": "37565", "database": "ChEBI", "url": "" }, { "id": "ZINC000060094177", "database": "ZINC", "url": "" }, { "id": "C00044", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-GGA-163267", "participant_name": "POLRMT [mitochondrial matrix]", "crossref": [ { "id": "ENSGALG00010027511", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010066640", "database": "ENSEMBL", "url": "" }, { "id": "XP_418204.3", "database": "RefSeq", "url": "" }, { "id": "E1BZ13", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010040801", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NT61", "gene_name": "GLUD2", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A1D5NT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT61" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A1D5NT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT61" } ] } ] }, { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5NYJ2", "gene_name": "LONP1", "activity": [ { "ec_number": "3.4.21.53", "activity": "Hydrolysis of proteins in presence of ATP.", "evidence": [ { "id": "A0A1D5NYJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYJ2" } ] }, { "ec_number": "3.4.21.53", "activity": "", "evidence": [ { "id": "A0A1D5NYJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYJ2" } ] } ] }, { "uniprot_ac": "A0A1D5P1U2", "gene_name": "PDHB", "activity": [ { "ec_number": "1.2.4.1", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "A0A1D5P1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1U2" } ] }, { "ec_number": "1.2.4.1", "activity": "", "evidence": [ { "id": "A0A1D5P1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1U2" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X2T8", "gene_name": "HSD17B10", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.239", "activity": "testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.178", "activity": "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.53", "activity": "androstan-3alpha,17beta-diol + NAD(+) = 17beta-hydroxyandrostanone + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.159", "activity": "cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H(+).", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.53", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.178", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.159", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] }, { "ec_number": "1.1.1.239", "activity": "", "evidence": [ { "id": "A0A8V0X2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2T8" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XA67", "gene_name": "ACADSB", "activity": [ { "ec_number": "1.3.8.1", "activity": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "A0A8V0XA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA67" } ] }, { "ec_number": "1.3.8.5", "activity": "2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "A0A8V0XA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA67" } ] }, { "ec_number": "1.3.8.1", "activity": "", "evidence": [ { "id": "A0A8V0XA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA67" } ] }, { "ec_number": "1.3.8.5", "activity": "", "evidence": [ { "id": "A0A8V0XA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA67" } ] } ] }, { "uniprot_ac": "A0A8V0XE68", "gene_name": "ACAT1", "activity": [ { "ec_number": "2.3.1.9", "activity": "2 acetyl-CoA = acetoacetyl-CoA + CoA.", "evidence": [ { "id": "A0A8V0XE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE68" } ] }, { "ec_number": "2.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE68" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XIM8", "gene_name": "HADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V0XIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIM8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V0XIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIM8" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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} ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUH5", "gene_name": "NADK2", "activity": [ { "ec_number": "2.7.1.23", "activity": "NAD(+) + ATP = ADP + NADP(+) + H(+).", "evidence": [ { "id": "A0A8V0YUH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH5" } ] }, { "ec_number": "2.7.1.23", "activity": "", "evidence": [ { "id": "A0A8V0YUH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH5" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0YYX3", "gene_name": "ECI1", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V0YYX3", "database": "UniProtKB", "url": 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"ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZX51", "gene_name": "PCCB", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZX51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX51" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "A0A8V0ZX51", 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2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A624", "gene_name": "ATP5B", "activity": [ { "ec_number": "7.1.2.2", "activity": "ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out).", "evidence": [ { "id": "A0A8V1A624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A624" } ] }, { "ec_number": "7.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V1A624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A624" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ABW8", "gene_name": "ALDH2", "activity": [ { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "A0A8V1ABW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABW8" } ] }, { "ec_number": "1.2.1.3", "activity": "", "evidence": [ { "id": "A0A8V1ABW8", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] } ] }, { "uniprot_ac": "A0A8V1AFG8", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BSC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC0" } ] } ] }, { "uniprot_ac": "E1BVT3", "gene_name": "MDH2", "activity": [ { "ec_number": "1.1.1.37", "activity": "(S)-malate + NAD(+) = oxaloacetate + NADH + H(+).", "evidence": [ { "id": "E1BVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVT3" } ] }, { "ec_number": "1.1.1.37", "activity": "", "evidence": [ { "id": "E1BVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVT3" } ] } ] }, { "uniprot_ac": "E1BY42", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "E1BZ13", "gene_name": "POLRMT", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BZ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ13" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "E1BZ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ13" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NLP2", "gene_name": "PDK1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "F1NLP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLP2" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NNW2", "gene_name": "ACAD8", "activity": [ { "ec_number": "1.3.8.5", "activity": "2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "F1NNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNW2" } ] }, { "ec_number": "1.3.8.5", "activity": "", "evidence": [ { "id": "F1NNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNW2" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] } ] }, { "uniprot_ac": "O12944", "gene_name": "RAD54L", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O12944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12944" } ] } ] }, { "uniprot_ac": "O93257", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "O93257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93257" } ] }, { "ec_number": "4.2.99.18", 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"A0A8V0Z691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ] } ], "protein_names": [ { "name": "Mediator complex subunit 12", "type": "synonym", "evidence": [ { "id": "A0A8V0Z691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MED12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691", "locus": { "chromosome": "4", "start_pos": 2310927, "end_pos": 2345502, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018395", "url": "https://www.ensembl.org/id/ENSGALG00010018395" } ] } } ], "crossref": [ { "id": "422210", "url": "https://www.ncbi.nlm.nih.gov/gene/422210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422210", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQQSHDK", "url": "https://omabrowser.org/oma/group/YQQSHDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z684", "url": "https://www.orthodb.org/?gene=A0A8V0Z684", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z691", "url": "https://www.orthodb.org/?gene=A0A8V0Z691", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z789", "url": "https://www.orthodb.org/?gene=A0A8V0Z789", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD59", "url": "https://www.orthodb.org/?gene=A0A8V0ZD59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46007", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46007", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46007:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46007:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z684", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z684", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z684-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z684-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z691-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z789", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z789", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z789-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z789-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQSCGSPAGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPMDIDHNSSTIFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSAEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQTVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRQQQQQQQQQQQQQQQQQQQQQQQQPPPPQPQPQQQPQVSTVPQPQAQGQPPGLGMQALPPQQPIVSVPLETEERDSPAQTRLCSTCFLPRLLPLLFPQTCVSAEAASQVLWL", "length": 2174, "header": "tr|A0A8V0Z691-1|A0A8V0Z691_CHICK Isoform 1 of Mediator complex subunit 12 OS=Gallus gallus OX=9031 GN=MED12 PE=1 SV=1 CANONICAL=A0A8V0Z691-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z684-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691/entry#A0A8V0Z684-1", "sequence": { "sequence": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQSCGSPAGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPMDIDHNSSTIFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSAEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQTVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRVRACIS", "length": 2068, "header": "tr|A0A8V0Z684-1|A0A8V0Z691_CHICK Computationally mapped isoform of Mediator complex subunit 12 OS=Gallus gallus OX=9031 GN=MED12 PE=1 SV=1 CANONICAL=A0A8V0Z691-1" }, "locus": { "chromosome": "4", "start_pos": 2345456, "end_pos": 2315072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044427.1", "url": "https://www.ensembl.org/id/ENSGALT00010044427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026440.1", "url": "https://www.ensembl.org/id/ENSGALP00010026440.1" } ] } }, { "isoform_ac": "A0A8V0Z691-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691/entry#A0A8V0Z691-1", "sequence": { "sequence": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQSCGSPAGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPMDIDHNSSTIFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSAEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQTVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRQQQQQQQQQQQQQQQQQQQQQQQQPPPPQPQPQQQPQVSTVPQPQAQGQPPGLGMQALPPQQPIVSVPLETEERDSPAQTRLCSTCFLPRLLPLLFPQTCVSAEAASQVLWL", "length": 2174, "header": "tr|A0A8V0Z691-1|A0A8V0Z691_CHICK Isoform 1 of Mediator complex subunit 12 OS=Gallus gallus OX=9031 GN=MED12 PE=1 SV=1 CANONICAL=A0A8V0Z691-1" }, "locus": { "chromosome": "4", "start_pos": 2345456, "end_pos": 2313481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044432.1", "url": "https://www.ensembl.org/id/ENSGALT00010044432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026445.1", "url": "https://www.ensembl.org/id/ENSGALP00010026445.1" } ] } }, { "isoform_ac": "A0A8V0Z789-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691/entry#A0A8V0Z789-1", "sequence": { "sequence": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQSCGSPAGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPMDIDHNSSTIFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSAEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQTVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRQQQQQQQQQQQQQQQQQQQQQQQQPPPPQPQPQQQPQVSTVPQPQAQGQPPGLGMQALPPQQPIFQRQGLQQTQQQQQTAALVRQLQQQLSSKPRCS", "length": 2159, "header": "tr|A0A8V0Z789-1|A0A8V0Z789_CHICK Computationally mapped isoform of Mediator complex subunit 12 OS=Gallus gallus OX=9031 GN=MED12 PE=1 SV=1 CANONICAL=A0A8V0Z691-1" }, "locus": { "chromosome": "4", "start_pos": 2345456, "end_pos": 2313359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044437.1", "url": "https://www.ensembl.org/id/ENSGALT00010044437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026449.1", "url": "https://www.ensembl.org/id/ENSGALP00010026449.1" } ] } }, { "isoform_ac": "A0A8V0ZD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691/entry#A0A8V0ZD59-1", "sequence": { "sequence": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQSCGSPAGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPMDIDHNSSTIFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSAEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQTVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRQQQQQQQQQQQQQQQQQQQQQQQQPPPPQPQPQQQPQVSTVPQPQAQGQPPGLGMQALPPQQPIFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQQNNNPFGRY", "length": 2167, "header": "tr|A0A8V0ZD59-1|A0A8V0ZD59_CHICK Computationally mapped isoform of Mediator complex subunit 12 OS=Gallus gallus OX=9031 GN=MED12 PE=1 SV=1 CANONICAL=A0A8V0Z691-1" }, "locus": { "chromosome": "4", "start_pos": 2345456, "end_pos": 2311311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044444.1", "url": "https://www.ensembl.org/id/ENSGALT00010044444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026452.1", "url": "https://www.ensembl.org/id/ENSGALP00010026452.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1395, "start_aa": "Thr", "end_pos": 1395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1395", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1741, "start_aa": "Thr", "end_pos": 1741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1741", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1925, "start_aa": "Thr", "end_pos": 1925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1925", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422210", "resource": "KEGG Pathway" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MKF8-1", "protein_name": "Mediator complex subunit 12", "gene_name": "Med12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRPGPAGSGVCGSAIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVNSHSSHVISAQSTSSLPTTPAPQPPTSNTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGTPGPRPPSPFDDPADDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKDVKPPPKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFVFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDSEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKAKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPALLEPEKKAPEPPKTDKPGTAPPSTEERKKKSTKGKKRSQPATKSEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTTVMGLEPSSYKTSVYRQQQPTVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYGLQSSQGYTSYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMMGTMTPLSAQGVQAGVRSTSILPEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQPQQQQPHQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY", "length": 2190 }, "evidence": [ { "id": "A0A8V0Z691", "url": "https://omabrowser.org/oma/group/A0A8V0Z691/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AGH6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "Med12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVIAAQSTSSLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPTDDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPAKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPALLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKNEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMSTVMGLEPSSYKTSVYRQQQPTVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYGLQTSQGYTSYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMMGTMTPLSAQGVQAGVRSTSILPEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQMLRQQQQQQQQQQQQQQQQQQQQQQQQQQQPHQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY", "length": 2190 }, "evidence": [ { "id": "A0A8V0Z691", "url": "https://omabrowser.org/oma/group/A0A8V0Z691/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93074-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "MED12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDLAGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKRHVDPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY", "length": 2177 }, "evidence": [ { "id": "A0A8V0Z691", "url": "https://omabrowser.org/oma/group/A0A8V0Z691/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VW47-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "kto", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSMLQEKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLSDEFGTAHNSNVNASKVSAFFSGVLAKKEELMTLPDTGRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAKRAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIKFMKELLPKLQEYYQQNHDKSSSNGTTSGSLTAAGNGPASNGSTGTSSINSVTGSSASTNVIPVPSMASPLPPIHSPANGQQAAPGGGVNAGSVMPTTGSLGGVVGGPGSSVVGGAAGAGAAVPPGSTISGIGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFALQYMHDFVQSERLCRKMAYIVSKKLAQLLNTVVEQQTIKELDEPKLQQDPYELALQEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRAPSSLLGSPLDHLPLAPSVLPMPTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRWFAAKWLSAGKNQYTSVLATLDHLDTHCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWAVSGQRWGEHRAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLDHDAPVLDEHVSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESVLVIKSGTTATKTSPPPPAPPPTTTHGFDDDGFGGGLDFKHNEFDDSNVDDDLDKLVQNIKEKGQQHEAPDSPKIGPPGDGETNPGGSISRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVAAAGHVKKHSRNEFNFEATTSKCQQMAYFDQHVVTAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLMELALNIYSLLELCDSLLKELPEVEHQLQLKKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTLSVFEGVCRTIRHVSNPSECTSAERCIIAYLSDLHESCVLLQGKEQSTEYYQQLQCIKRFKDIFNTPEQLDLPPQGYNPLLLQELFMAPRRGGKLDPHWLGTLHESPANVYSFVSNALIAVCRETDNERLNDVALACAELTASCNVLSEEWIYALQSLCSGSKSPRYPHLGGQVDIGQLKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGNDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLASGSGTSSGGLGGAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSSLTSEPEALQQPSVGGMEQISLLEFAQAVLKQICAQEHVLERCLKNAEQLCDMIIDEMLTAKQAQRVLHMICYPEPEFNIISELDQRSMIVRILENLGQWTLRISWLDLQLMYRQSLSNNAELNVWLDTVARAAIDVFHMEEVVLPGAVKATHKPKPSTWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGLGGVPARNKKMPLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQCLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSDDERHYMNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHSGMDTKGNKICDIDKKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPPEDIEPVPEKICIKDEMKADTPSSVDQSPSAVVGGTGRGRGKGTTTRKRKPKNPKTPPVVNTQQQQPQLAQQPQQPQNVQQQQLQQQQQQQQHMQQQHMQQQQMQPNQMGQMPMNMPMNMQQFAPNPNNMMQQNAMLQQQQQQQMQQMGNNPMQQQLNVGGGNGQPNPQMNFMQQGPGGGGAGPQGMPGQQQQWHNAPQQQQPPQPYHNQYAPHQQNMQSNRIERPPLNANSKQALSQMLRQRQPFQQQAQQGPGGGFNPMQQQPQASQQQPGPQQQMNPNQMRQQQMNPQQNPQSVAAFNAMQQQPQQNAQQQQMNPNQQQQQQFMRGGNMRPGMAPNQMNQMNMGGQGMSQNPMMQQQIPQNMVGMVNPNANQMMQSGGAQGGNGVGVGVGVGVGGAGNNPNMGMGGMPQQGMIQQQPQQQPQQQVQFQNFQNQYQQQQQQGMQQQGGGAGVGVGVGMAPNQQQQQQANMMGNFNPQMQQGNRNNPDFMAAAAVAQQQQQQQQQQRVVPGGMMAGNRNQYMNQAPNVTMSTMMGPGPGGVVGQVPPYARQQSAGGGKPGVLNTQQQFQQQQQQQQQLRHQMMQLQGMGGGAGGGMGAGPQQGGGAVGGGAGGGMVPQQQSMNQQQTPNLVAQLQRQNMMGQQQYQPPPY", "length": 2531 }, "evidence": [ { "id": "A0A8V0Z691", "url": "https://omabrowser.org/oma/group/A0A8V0Z691/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z691", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z691" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1387, "end_pos": 1389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1399, "end_pos": 1401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1579, "end_pos": 1581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1782, "end_pos": 1784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": 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"uniprot_canonical_ac": "A0A8V0Z694-1", "uniprot_ac": "A0A8V0Z694", "uniprot_id": "A0A8V0Z694_CHICK", "mass": { "chemical_mass": 37482.0, "monoisotopic_mass": 37482.0 }, "refseq": {}, "gene_names": [ { "name": "AAGAB", "type": "recommended", "evidence": [ { "id": "A0A8V0Z694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694" } ] } ], "protein_names": [ { "name": "Alpha- and gamma-adaptin binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z694", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AAGAB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694", "locus": { "chromosome": "10", "start_pos": 18880261, "end_pos": 18898747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018150", "url": "https://www.ensembl.org/id/ENSGALG00010018150" } ] } } ], "crossref": [ { "id": "A0A8V0Z694", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z694", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4P1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Q1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z694", "url": "https://www.orthodb.org/?gene=A0A8V0Z694", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC63", "url": "https://www.orthodb.org/?gene=A0A8V0ZC63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14659", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14659", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14659:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14659:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4P1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z694", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z694-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGPYALLSSCDGGFAAEELVRRITGREDLTVGATTTGGVSFYPWTIDNKYYSADIHLCVVPNTALVTGAIAESVQAFVVYFDSSIKSGLDGVSEWLPLTEEWLPEVMILVCNRVSEHGVNRQKAQEWCIKHGFELVELNPEELPDEDDDFPESTGVKRIVQALNANVWSNVVMKNDRTQGFGLLSTLAGANCSIGSEENQDTESNPAAADREEPHLDNREDAASTNDLQIDSVVDPVLDTDIQELASLTTRDGDLENFERLFSKLKEMKGTKKLQRCPMNKENYMQKRWPKRSGWRLEETEMKLKVSPRMKKTEVFCSCKQRSDLKSDLFLQ", "length": 335, "header": "tr|A0A8V0Z694-1|A0A8V0Z694_CHICK Isoform 1 of Alpha- and gamma-adaptin binding protein OS=Gallus gallus OX=9031 GN=AAGAB PE=1 SV=1 CANONICAL=A0A8V0Z694-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694/entry#A0A8V0Z4P1-1", "sequence": { "sequence": "MAAAGPYALLSSCDGGFAAEELVRRITGREDLTVGATTTGGVSFYPWTIDNKYYSADIHLCVVPNTALVTGAIAESVQAFVVYFDSSIKSGLDGVSEWLPLTEEWLPEVMILVCNRVSEHGVNRQKAQEWCIKHGFELVELNPEELPDEDDRTQGFGLLSTLAGANCSIGSEENQDTESNPAAADREEPHLDNREDAASTNDLQIDSVVDPVLDTDIQELASLTTRDGDLENFERLFSKLKEMKEKAATLPHEQRKLHAEKVAKAFWMAIGGDRDEIEGLSSDEEN", "length": 286, "header": "tr|A0A8V0Z4P1-1|A0A8V0Z4P1_CHICK Computationally mapped isoform of Alpha- and gamma-adaptin binding protein OS=Gallus gallus OX=9031 GN=AAGAB PE=1 SV=1 CANONICAL=A0A8V0Z694-1" }, "locus": { "chromosome": "10", "start_pos": 18898709, "end_pos": 18882674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043854.1", "url": "https://www.ensembl.org/id/ENSGALT00010043854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026080.1", "url": "https://www.ensembl.org/id/ENSGALP00010026080.1" } ] } }, { "isoform_ac": "A0A8V0Z4Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694/entry#A0A8V0Z4Q1-1", "sequence": { "sequence": "MAAAGPYALLSSCDGGFAAEELVRRITGREDLTVGATTTGGVSFYPWTIDNKYYSADIHLCVVPNTALVTGAIAESVQAFVVYFDSSIKSGLDGVSEWLPLTEEWLPEVMILVCNRVSEHDDFPESTGVKRIVQALNANVWSNVVMKNDRTQGFGLLSTLAGANCSIGSEENQDTESNPAAADREEPHLDNREDAASTNDLQIDSVVDPVLDTDIQELASLTTRDGDLENFERLFSKLKEMKEKAATLPHEQRKLHAEKVAKAFWMAIGGDRDEIEGLSSDEEN", "length": 284, "header": "tr|A0A8V0Z4Q1-1|A0A8V0Z4Q1_CHICK Computationally mapped isoform of Alpha- and gamma-adaptin binding protein OS=Gallus gallus OX=9031 GN=AAGAB PE=1 SV=1 CANONICAL=A0A8V0Z694-1" }, "locus": { "chromosome": "10", "start_pos": 18898709, "end_pos": 18882674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043872.1", "url": "https://www.ensembl.org/id/ENSGALT00010043872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026090.1", "url": "https://www.ensembl.org/id/ENSGALP00010026090.1" } ] } }, { "isoform_ac": "A0A8V0Z694-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694/entry#A0A8V0Z694-1", "sequence": { "sequence": "MAAAGPYALLSSCDGGFAAEELVRRITGREDLTVGATTTGGVSFYPWTIDNKYYSADIHLCVVPNTALVTGAIAESVQAFVVYFDSSIKSGLDGVSEWLPLTEEWLPEVMILVCNRVSEHGVNRQKAQEWCIKHGFELVELNPEELPDEDDDFPESTGVKRIVQALNANVWSNVVMKNDRTQGFGLLSTLAGANCSIGSEENQDTESNPAAADREEPHLDNREDAASTNDLQIDSVVDPVLDTDIQELASLTTRDGDLENFERLFSKLKEMKGTKKLQRCPMNKENYMQKRWPKRSGWRLEETEMKLKVSPRMKKTEVFCSCKQRSDLKSDLFLQ", "length": 335, "header": "tr|A0A8V0Z694-1|A0A8V0Z694_CHICK Isoform 1 of Alpha- and gamma-adaptin binding protein OS=Gallus gallus OX=9031 GN=AAGAB PE=1 SV=1 CANONICAL=A0A8V0Z694-1" }, "locus": { "chromosome": "10", "start_pos": 18898709, "end_pos": 18882616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043865.1", "url": "https://www.ensembl.org/id/ENSGALT00010043865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026086.1", "url": "https://www.ensembl.org/id/ENSGALP00010026086.1" } ] } }, { "isoform_ac": "A0A8V0ZC63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694/entry#A0A8V0ZC63-1", "sequence": { "sequence": "MAAAGPYALLSSCDGGFAAEELVRRITGREDLTVGATTTGGVSFYPWTIDNKYYSADIHLCVVPNTALVTGAIAESVQAFVVYFDSSIKSGLDGVSEWLPLTEEWLPEVMILVCNRVSEHGVNRQKAQEWCIKHGFELVELNPEELPDEDDDFPESTGVKRIVQALNANVWSNVVMKNDRTQGFGLLSTLAGANCSIGSEENQDTESNPAAADREEPHLDNREDAASTNDLQIDSVVDPVLDTDIQELASLTTRDGDLENFERLFSKLKEMKGGQSVLDGDWRRQR", "length": 286, "header": "tr|A0A8V0ZC63-1|A0A8V0ZC63_CHICK Computationally mapped isoform of Alpha- and gamma-adaptin binding protein OS=Gallus gallus OX=9031 GN=AAGAB PE=1 SV=1 CANONICAL=A0A8V0Z694-1" }, "locus": { "chromosome": "10", "start_pos": 18898709, "end_pos": 18882708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043880.1", "url": "https://www.ensembl.org/id/ENSGALT00010043880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026095.1", "url": "https://www.ensembl.org/id/ENSGALP00010026095.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z694", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z694" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6B5-1", "uniprot_ac": "A0A8V0Z6B5", "uniprot_id": "A0A8V0Z6B5_CHICK", "mass": { "chemical_mass": 12903.0, "monoisotopic_mass": 12903.0 }, "refseq": { "ac": "XP_015139167", "name": "cytochrome c oxidase subunit VIIa polypeptide 2 like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139167" }, "gene_names": [ { "name": "COX7A2L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5" } ] }, { "name": "COX7A2L", "type": "synonym", "evidence": [ { "id": "XP_015139167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139167" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5/entry#names_and_taxonomy" } ] }, { "name": "Supercomplex assembly factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit VIIa polypeptide 2 like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139167" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139167" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COX7A2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5", "locus": { "chromosome": "3", "start_pos": 23581826, "end_pos": 23588274, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020168", "url": "https://www.ensembl.org/id/ENSGALG00010020168" } ] } } ], "crossref": [ { "id": "A0A8V0Z6B5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00928", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00928", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421392", "url": "https://www.ncbi.nlm.nih.gov/gene/421392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TVEYMGA", "url": "https://omabrowser.org/oma/group/TVEYMGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6B5", "url": "https://www.orthodb.org/?gene=A0A8V0Z6B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD46", "url": "https://www.orthodb.org/?gene=A0A8V0ZD46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10510:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10510:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139167", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD46", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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"+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020171", "url": "https://www.ensembl.org/id/ENSGALG00010020171" } ] } } ], "crossref": [ { "id": "A0A8V0Z6C4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6C4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6C4", "url": "https://www.orthodb.org/?gene=A0A8V0Z6C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC71", "url": "https://www.orthodb.org/?gene=A0A8V0ZC71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD50", "url": "https://www.orthodb.org/?gene=A0A8V0ZD50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12790", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12790", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12790:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12790:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGDEFISSPPKKTVRFGGTLTDILLKYERGETTDFELLKHQLSDPDIKKLPWLRRSREVVEEYLGFLGNLVSAQTVHLRPCLSMIVSQFVPPRIIIREDDVDISDSDDDEENLSENFDTCHRALQTVAKYVPSTLQFLMPILVEKFPFINKSERTLECYVHNLLRVTVYLPTLRLQILELIVEKLLKLDVSTPQQDIEDAEEAANNSDSEEKSTEEGLFDMEEDEERKENKVSPSSERMAHPLAERLDILMTILFAYIKDVCHVDGKLDINKTKDLYRDLVSVFDKLILPTHASCHVQYFIFHICSLKSGLAEAFLDHLWKKLQDPNNPSVIRQTAGSYIGSFLARAKFIPVVTVKACLDLLVNWMHKYIDNQDTGANAYCDVALHGPFYSACQAAFYTLIFRHKQLLDGNLRKGLSYLQSLNFERIVMCQLNPLKICIPSVVNLFAAITRKYQLVFCYTIIERNNRQFIPVVRSGTGGDFVQMCTNPLDSFFPFDPYVLKRSKKTIDPFYQFWEELSAEDLENLKKPIKKGTSEDEDDDFLKGETPQNEGVVEITPNSYESNTRSPVSSIGSPSDCHAQYLESCAH", "length": 589, "header": "tr|A0A8V0Z6C4-1|A0A8V0Z6C4_CHICK Isoform 1 of RRN3 homolog, RNA polymerase I transcription factor OS=Gallus gallus OX=9031 GN=RRN3 PE=3 SV=1 CANONICAL=A0A8V0Z6C4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4/entry#A0A8V0Z6C4-1", "sequence": { "sequence": "MLAGDEFISSPPKKTVRFGGTLTDILLKYERGETTDFELLKHQLSDPDIKKLPWLRRSREVVEEYLGFLGNLVSAQTVHLRPCLSMIVSQFVPPRIIIREDDVDISDSDDDEENLSENFDTCHRALQTVAKYVPSTLQFLMPILVEKFPFINKSERTLECYVHNLLRVTVYLPTLRLQILELIVEKLLKLDVSTPQQDIEDAEEAANNSDSEEKSTEEGLFDMEEDEERKENKVSPSSERMAHPLAERLDILMTILFAYIKDVCHVDGKLDINKTKDLYRDLVSVFDKLILPTHASCHVQYFIFHICSLKSGLAEAFLDHLWKKLQDPNNPSVIRQTAGSYIGSFLARAKFIPVVTVKACLDLLVNWMHKYIDNQDTGANAYCDVALHGPFYSACQAAFYTLIFRHKQLLDGNLRKGLSYLQSLNFERIVMCQLNPLKICIPSVVNLFAAITRKYQLVFCYTIIERNNRQFIPVVRSGTGGDFVQMCTNPLDSFFPFDPYVLKRSKKTIDPFYQFWEELSAEDLENLKKPIKKGTSEDEDDDFLKGETPQNEGVVEITPNSYESNTRSPVSSIGSPSDCHAQYLESCAH", "length": 589, "header": "tr|A0A8V0Z6C4-1|A0A8V0Z6C4_CHICK Isoform 1 of RRN3 homolog, RNA polymerase I transcription factor OS=Gallus gallus OX=9031 GN=RRN3 PE=3 SV=1 CANONICAL=A0A8V0Z6C4-1" }, "locus": { "chromosome": "14", "start_pos": 105006, "end_pos": 92193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048723.1", "url": "https://www.ensembl.org/id/ENSGALT00010048723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028797.1", "url": "https://www.ensembl.org/id/ENSGALP00010028797.1" } ] } }, { "isoform_ac": "A0A8V0ZC71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4/entry#A0A8V0ZC71-1", "sequence": { "sequence": "MLAGDEFISSPPKKTVRFGGTLTDILLKYERGETTDFELLKHQLSDPDIKDAQIINWLHEFRSSVAYLTKDFEQLVSILLKLPWLRRSREVVEEYLGFLGNLVSAQTVHLRPCLSMIVSQFVPPRIIIREDDVDISDSDDDEENLSENFDTCHRALQTVAKYVPSTLQFLMPILVEKFPFINKSERTLECYVHNLLRVTVYLPTLRLQILELIVEKLLKLDVSTPQQDIEDAEEAANNSDSEEKSTEEGLFDMEEDEERKENKVSPSSERMAHPLAERLDILMTILFAYIKDVCHVDGKLDINKTKDLYRDLVSVFDKLILPTHASCHVQYFIFHICSLKSGLAEAFLDHLWKKLQDPNNPSVIRQTAGSYIGSFLARAKFIPVVTVKACLDLLVNWMHKYIDNQDTGANAYCDVALHGPFYSACQAAFYTLIFRHKQLLDGNLRKGLSYLQSLNFERIVMCQLNPLKICIPSVVNLFAAITRKYQLVFCYTIIERNNRQFIPVVRSGTGGDFVQMCTNPLDSFFPFDPYVLKRCS", "length": 536, "header": "tr|A0A8V0ZC71-1|A0A8V0ZC71_CHICK Computationally mapped isoform of RRN3 homolog, RNA polymerase I transcription factor OS=Gallus gallus OX=9031 GN=RRN3 PE=3 SV=1 CANONICAL=A0A8V0Z6C4-1" }, "locus": { "chromosome": "14", "start_pos": 105006, "end_pos": 94187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048732.1", "url": "https://www.ensembl.org/id/ENSGALT00010048732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028804.1", "url": "https://www.ensembl.org/id/ENSGALP00010028804.1" } ] } }, { "isoform_ac": "A0A8V0ZD50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4/entry#A0A8V0ZD50-1", "sequence": { "sequence": "MLAGDEFISSPPKKTVRFGGTLTDILLKYERGETTDFELLKHQLSDPDIKDAQIINWLHEFRSSVAYLTKDFEQLVSILLKLPWLRRSREVVEEYLGFLGNLVSAQTVHLRPCLSMIVSQFVPPRIIIREDDVDISDSDDDEENLSENFDTCHRALQTVAKYVPSTLQFLMPILVEKFPFINKSERTLECYVHNLLRVTVYLPTLRLQILELIVEKLLKLDVSTPQQDIEDAEEAANNSDSEEKSTEEGLFDMEEDEERKENKVSPSSERMAHPLAERLDILMTILFAYIKDVCHVDGKLDINKTKDLYRDLVSVFDKLILPTHASCHVQYFIFHICSLKSGLAEAFLDHLWKKLQDPNNPSVIRQTAGSYIGSFLARAKFIPVVTVKACLDLLVNWMHKYIDNQDTGANAYCDVALHGPFYSACQAAFYTLIFRHKQLLDGNLRKGNTSWCSATQLLRETIGSLYQLFGVALGVTSCRCALTRLTVSSPLIPMCSKDQRRPLIHFISFGKN", "length": 512, "header": "tr|A0A8V0ZD50-1|A0A8V0ZD50_CHICK Computationally mapped isoform of RRN3 homolog, RNA polymerase I transcription factor OS=Gallus gallus OX=9031 GN=RRN3 PE=3 SV=1 CANONICAL=A0A8V0Z6C4-1" }, "locus": { "chromosome": "14", "start_pos": 105006, "end_pos": 93721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048727.1", "url": "https://www.ensembl.org/id/ENSGALT00010048727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028801.1", "url": "https://www.ensembl.org/id/ENSGALP00010028801.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase I core promoter sequence-specific DNA binding", "id": "GO:0001164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" }, { "name": "RNA polymerase I general transcription initiation factor activity", "id": "GO:0001181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" }, { "name": "RNA polymerase I core binding", "id": "GO:0001042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6C4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6E1-1", "uniprot_ac": "A0A8V0Z6E1", "uniprot_id": "A0A8V0Z6E1_CHICK", "mass": { "chemical_mass": 45608.0, "monoisotopic_mass": 45608.0 }, "refseq": { "ac": "XP_414416", "name": "26S proteasome non-ATPase regulatory subunit 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414416" }, "gene_names": [ { "name": "PSMD6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1" } ] }, { "name": "PSMD6", "type": "synonym", "evidence": [ { "id": "XP_414416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414416" } ] } ], "protein_names": [ { "name": "26S proteasome non-ATPase regulatory subunit 6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome non-ATPase regulatory subunit 6", "type": "synonym", "evidence": [ { "id": "XP_414416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414416" } ] }, { "name": "26S proteasome regulatory subunit RPN7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414416.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414416" } ] }, { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. 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"R-GGA-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" }, { "id": "R-GGA-9762114", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762114", "resource": "Reactome", "description": "GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2" }, { "id": "R-GGA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" }, { "id": "R-GGA-9929356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929356", 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"MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM", "length": 389 }, "evidence": [ { "id": "A0A8V0Z6E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55C75-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 6", "gene_name": "psmD6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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"MDGGAEGSQQPHLILANKLFLLTHPDVPDIEKVQLKSEVLDFIRSHGMAPLYETLIASSVLDLDQSLLESMRAANEEELKKLDEKIADAEENLGESEVREAHLAKALYFIRISDKEKALEQLKLTEGKTVAVGQKMDVVFYTLQLAFFYMDFDLVSKSIDKAKKLFEEGGDWERKNRLKVYEGLYCMSTRNFKKAASLFLDSISTFTTYEIFPYETFIFYTVLTSIITLDRVSLKQKVVDAPEILTVLGKIPFLSEFLNSLYECQYKAFFSAFAGMAVQIKYDRYLYPHFRFYMREVRTVVYSQFLESYKSVTVEAMAKAFGVSVDFIDQELSRFIAAGKLHCKIDKVAGVLETNRPDAKNALYQATIKQGDFLLNRIQKLSRVIDL", "length": 387 }, "evidence": [ { "id": "A0A8V0Z6E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99JI4-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 6", "gene_name": "Psmd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVREELMAAVRENNMAPYYEALCKSLDWQMDVDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM", "length": 389 }, "evidence": [ { "id": "A0A8V0Z6E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3G7-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 6", "gene_name": "Rpn7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAENLEEQGLEKNPNLELAQTKFLLTLAEYKQDAALKAKLLEAIRTENMAPWYEHICSELGWTVDKDLLARMKENNRVEVEQLDAAIEDAEKNLGEMEVREANLKKSEYLCRIGDKAAAETAFRKTYEKTVSLGHRLDIVFHLIRLGLFYLDHDLITRNIDKAKYLIEEGGDWDRRNRLKVYQGVYSVAVRDFKAAATFFLDTVSTFTSYELMDYPTFVRYTVYVAMIALPRNELRDKVIKGSEIQEVLHGLPDVKQFLFSLYNCQYENFYVHLAGVEKQLRLDYLIHPHYRYYVREMRILGYTQLLESYRSLTLQYMAESFGVTVEYIDQELARFIAAGRLHAKVDRVGGIVETNRPDNKNWQYQATIKQGDLLLNRIQKLSRVINI", "length": 389 }, "evidence": [ { "id": "A0A8V0Z6E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "proteasome regulatory particle", "id": "GO:0005838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E1" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 361, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6E4-1", "uniprot_ac": "A0A8V0Z6E4", "uniprot_id": "A0A8V0Z6E4_CHICK", "mass": { "chemical_mass": 71936.0, "monoisotopic_mass": 71936.0 }, "refseq": {}, "gene_names": [ { "name": "IGFALS", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ] } ], "protein_names": [ { "name": "Insulin-like growth factor-binding protein complex acid labile subunit", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGFALS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4", "locus": { "chromosome": "14", "start_pos": 13214503, "end_pos": 13209676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018423", "url": "https://www.ensembl.org/id/ENSGALG00010018423" } ] } } ], "crossref": [ { "id": "A0A8V0Z6E4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6E4", "database": "AlphaFoldDB", "categories": [] }, { "id": "427649", "url": "https://www.ncbi.nlm.nih.gov/gene/427649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427649", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFLHTQN", "url": "https://omabrowser.org/oma/group/TFLHTQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6E4", "url": "https://www.orthodb.org/?gene=A0A8V0Z6E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD96", "url": "https://www.orthodb.org/?gene=A0A8V0ZD96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24373:SF275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24373:SF275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMERMWEQSLSTNMATEHRRPLLVPWAGRVPLLLPLVLLLAAASQPQDGDVPKEPSAMEPLRCPSPCACSLDDYSEELNVFCSGRNLTQLPDDFPTNAKAIWLDGNNFTQLPAAAFRNLSGLDFLDLQSSQLAAVEQHAFHGLRSLYHLHLERNRLKYLAPHTFLHTQNLVSLSLNNNLFSKVEEGLFAGLSNLWYLNLGWNSLVVLPDKVFHDLPNLRELILAGNKLPYLQHQLFCSLTELKELDLSGNALKGIKINIFVKLQKLQKLYLNNNQINAIAPRAFMGMKSLRWLDLSHNRLTSLYEDTFLGLLSLHVLRLSTNSITSLRPRTFKDLQFLEELQLGHNRIWSLAERTFDGLGQLEVLSLNNNQLQDIKAGAFLGLYNVAVMHLSANCIKTLPEYVFEGVTKLHSLHLEHSCLSKIRANTFSSLTSLRRLFLQHNAISTIEDQSFRELHELLELDLKHNRLSHLSPQLFVGLSNLEYLFLSFNQIMDISQNTFSPLRRLFWLDLSHNQLATLDNAVITQLANLRYLSLKNNSLETFSVGFLCPSFTLEQLWLGGNNWHCNCSLKGLRDFALRHPTVVPRFVQSVAEGDDSHVPVYTYNNLTCCQPPSLVGLDLRDIREENFAHC", "length": 632, "header": "tr|A0A8V0Z6E4-1|A0A8V0Z6E4_CHICK Isoform 1 of Insulin-like growth factor-binding protein complex acid labile subunit OS=Gallus gallus OX=9031 GN=IGFALS PE=1 SV=1 CANONICAL=A0A8V0Z6E4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4/entry#A0A8V0Z6E4-1", "sequence": { "sequence": "MRMERMWEQSLSTNMATEHRRPLLVPWAGRVPLLLPLVLLLAAASQPQDGDVPKEPSAMEPLRCPSPCACSLDDYSEELNVFCSGRNLTQLPDDFPTNAKAIWLDGNNFTQLPAAAFRNLSGLDFLDLQSSQLAAVEQHAFHGLRSLYHLHLERNRLKYLAPHTFLHTQNLVSLSLNNNLFSKVEEGLFAGLSNLWYLNLGWNSLVVLPDKVFHDLPNLRELILAGNKLPYLQHQLFCSLTELKELDLSGNALKGIKINIFVKLQKLQKLYLNNNQINAIAPRAFMGMKSLRWLDLSHNRLTSLYEDTFLGLLSLHVLRLSTNSITSLRPRTFKDLQFLEELQLGHNRIWSLAERTFDGLGQLEVLSLNNNQLQDIKAGAFLGLYNVAVMHLSANCIKTLPEYVFEGVTKLHSLHLEHSCLSKIRANTFSSLTSLRRLFLQHNAISTIEDQSFRELHELLELDLKHNRLSHLSPQLFVGLSNLEYLFLSFNQIMDISQNTFSPLRRLFWLDLSHNQLATLDNAVITQLANLRYLSLKNNSLETFSVGFLCPSFTLEQLWLGGNNWHCNCSLKGLRDFALRHPTVVPRFVQSVAEGDDSHVPVYTYNNLTCCQPPSLVGLDLRDIREENFAHC", "length": 632, "header": "tr|A0A8V0Z6E4-1|A0A8V0Z6E4_CHICK Isoform 1 of Insulin-like growth factor-binding protein complex acid labile subunit OS=Gallus gallus OX=9031 GN=IGFALS PE=1 SV=1 CANONICAL=A0A8V0Z6E4-1" }, "locus": { "chromosome": "14", "start_pos": 13213517, "end_pos": 13209958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044517.1", "url": "https://www.ensembl.org/id/ENSGALT00010044517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026500.1", "url": "https://www.ensembl.org/id/ENSGALP00010026500.1" } ] } }, { "isoform_ac": "A0A8V0ZD96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4/entry#A0A8V0ZD96-1", "sequence": { "sequence": "MSADRAGRVPLLLPLVLLLAAASQPQDGDVPKEPSAMEPLRCPSPCACSLDDYSEELNVFCSGRNLTQLPDDFPTNAKAIWLDGNNFTQLPAAAFRNLSGLDFLDLQSSQLAAVEQHAFHGLRSLYHLHLERNRLKYLAPHTFLHTQNLVSLSLNNNLFSKVEEGLFAGLSNLWYLNLGWNSLVVLPDKVFHDLPNLRELILAGNKLPYLQHQLFCSLTELKELDLSGNALKGIKINIFVKLQKLQKLYLNNNQINAIAPRAFMGMKSLRWLDLSHNRLTSLYEDTFLGLLSLHVLRLSTNSITSLRPRTFKDLQFLEELQLGHNRIWSLAERTFDGLGQLEVLSLNNNQLQDIKAGAFLGLYNVAVMHLSANCIKTLPEYVFEGVTKLHSLHLEHSCLSKIRANTFSSLTSLRRLFLQHNAISTIEDQSFRELHELLELDLKHNRLSHLSPQLFVGLSNLEYLFLSFNQIMDISQNTFSPLRRLFWLDLSHNQLATLDNAVITQLANLRYLSLKNNSLETFSVGFLCPSFTLEQLWLGGNNWHCNCSLKGLRDFALRHPTVVPRFVQSVAEGDDSHVPVYTYNNLTCCQPPSLVGLDLRDIREENFAHC", "length": 610, "header": "tr|A0A8V0ZD96-1|A0A8V0ZD96_CHICK Computationally mapped isoform of Insulin-like growth factor-binding protein complex acid labile subunit OS=Gallus gallus OX=9031 GN=IGFALS PE=1 SV=1 CANONICAL=A0A8V0Z6E4-1" }, "locus": { "chromosome": "14", "start_pos": 13213517, "end_pos": 13211127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044508.1", "url": "https://www.ensembl.org/id/ENSGALT00010044508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026492.1", "url": "https://www.ensembl.org/id/ENSGALP00010026492.1" } ] } }, { "isoform_ac": "A0A8V0ZDA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4/entry#A0A8V0ZDA0-1", "sequence": { "sequence": "MEPLRCPSPCACSLDDYSEELNVFCSGRNLTQLPDDFPTNAKAIWLDGNNFTQLPAAAFRNLSGLDFLDLQSSQLAAVEQHAFHGLRSLYHLHLERNRLKYLAPHTFLHTQNLVSLSLNNNLFSKVEEGLFAGLSNLWYLNLGWNSLVVLPDKVFHDLPNLRELILAGNKLPYLQHQLFCSLTELKELDLSGNALKGIKINIFVKLQKLQKLYLNNNQINAIAPRAFMGMKSLRWLDLSHNRLTSLYEDTFLGLLSLHVLRLSTNSITSLRPRTFKDLQFLEELQLGHNRIWSLAERTFDGLGQLEVLSLNNNQLQDIKAGAFLGLYNVAVMHLSANCIKTLPEYVFEGVTKLHSLHLEHSCLSKIRANTFSSLTSLRRLFLQHNAISTIEDQSFRELHELLELDLKHNRLSHLSPQLFVGLSNLEYLFLSFNQIMDISQNTFSPLRRLFWLDLSHNQLATLDNAVITQLANLRYLSLKNNSLETFSVGFLCPSFTLEQLWLGGNNWHCNCSLKGLRDFALRHPTVVPRFVQSVAEGDDSHVPVYTYNNLTCCQPPSLVGLDLRDIREENFAHC", "length": 574, "header": "tr|A0A8V0ZDA0-1|A0A8V0ZDA0_CHICK Computationally mapped isoform of Insulin-like growth factor-binding protein complex acid labile subunit OS=Gallus gallus OX=9031 GN=IGFALS PE=1 SV=1 CANONICAL=A0A8V0Z6E4-1" }, "locus": { "chromosome": "14", "start_pos": 13213517, "end_pos": 13211796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044512.1", "url": "https://www.ensembl.org/id/ENSGALT00010044512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026497.1", "url": "https://www.ensembl.org/id/ENSGALP00010026497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427649", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9QJJ1-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "igfals", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPFVLLLLHTLGTSVVLANPESKPSDQPRLSGDPKPSEEPTGQKSEPCAKGCTCLQDDYSLELNVYCSTRNFTQVPSDIPLSTRSLWLDGNLFSNLPAGAFEKLTNLEFLNLQSSLLVSLDAHAFRGLNSLAHLHLERNNLRSLSGLVFQGTSNLATLSLNNNQMFRIDDRLFAGMSHMWLLNLGWNLLSVLPETGFQDLHGLRELILAGNRLAYLQPQLFQGLNELKELDLTGNYLKVIKANVFLKLPKLQKLYLGQNQIVTVAPRAFVGMKSLRWLDLSRNRLTVLHDETFIGLQSLHVLRLSNNSINSLRPGTFRDLQYLEELCLYHNQIRALGVRVFEGLGHLEVLNLENNRLQEARMGTFMGLNHLAVMKLTGSCFHSLPDQVFKGLSKLHSIHLDRSCLTKVSSQSFSGLTGLRRLFLQHNNISLVERQSFVELQRLQQLDLRFNKLTTITSNTFYGLKNLDYLLLSGNLLHNLPAEALLPLQHLSWLDLSGNKLELILNATIYMLPRLRYLNLKDNILVNLPVSIPESLDQLWLSGNNWKCDCSAKPFRDFILQKPQVVPLQVEMLGEGEEPHTLITVYNNVTCASPSSASGLDLRNIAAEHFRDC", "length": 614 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P35858-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "IGFALS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALRKGGLALALLLLSWVALGPRSLEGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAPC", "length": 605 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35859-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "Igfals", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRTGGPALVVLLAFWVALGPCHLQGTDPGASADAEGPQCPVACTCSHDDYTDELSVFCSSKNLTHLPDDIPVSTRALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYYLHLERNRLRNLAVGLFTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVFVHLPRLQKLYLDRNLITAVAPGAFLGMKALRWLDLSHNRVAGLMEDTFPGLLGLHVLRLAHNAIASLRPRTFKDLHFLEELQLGHNRIRQLGERTFEGLGQLEVLTLNDNQITEVRVGAFSGLFNVAVMNLSGNCLRSLPERVFQGLDKLHSLHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTTNRLTHLPRQLFQGLGHLEYLLLSYNQLTTLSAEVLGPLQRAFWLDISHNHLETLAEGLFSSLGRVRYLSLRNNSLQTFSPQPGLERLWLDANPWDCSCPLKALRDFALQNPGVVPRFVQTVCEGDDCQPVYTYNNITCAGPANVSGLDLRDVSETHFVHC", "length": 603 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70389-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "Igfals", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALRTGSPALVVLLAFWVALGPCYLQGTDPGASADAEGPQCPVTCTCSYDDYTDELSVFCSSRNLTQLPDGIPVSTRALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYHLHLERNLLRSLAAGLFRHTPSLASLSLGNNLLGRLEEGLFRGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKLTYLQPALLCGLGELRELDLSRNALRSVKANVFIHLPRLQKLYLDRNLITAVAPRAFLGMKALRWLDLSHNRVAGLLEDTFPGLLGLHVLRLAHNAITSLRPRTFKDLHFLEELQLGHNRIRQLGEKTFEGLGQLEVLTLNDNQIHEVKVGAFFGLFNVAVMNLSGNCLRSLPEHVFQGLGRLHSLHLEHSCLGRIRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTANQLTHLPRQLFQGLGQLEYLLLSNNQLTMLSEDVLGPLQRAFWLDLSHNRLETPAEGLFSSLGRLRYLNLRNNSLQTFVPQPGLERLWLDANPWDCSCPLKALRDFALQNPGVVPRFVQTVCEGDDCQPVYTYNNITCAGPANVSGLDLRDISETLFVHC", "length": 603 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1KS52-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "IGFALS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALRKGGRALAALLVSWAALGPCTLAGTEPGAPSDAEGLPCPAACSCGHDDYTDELSVFCSSRNLTQLPDGIPDAARALWLDSNNFSSVPAGAFRNLSSLGFLNLQGSGLASLEPQALLGLQNLYHLHLERNQLRSLAAHTFLHTPGLASLGLHNNLLSRVEEGLFQGLTNLWDLNLGWNSLAVLPDTAFHGLANLRELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVFVKLPKLQKLYLDHNLLAAVAPGAFLGMKALRWLDLSHNRVGGLLEDTFPGLLGLHVLRLAHNALASLRPRTFKDLHFLEELQLGHNRLRQLPEKAFEGLGQLEVLALNDNQIQEIKAGAFLGLFNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEHSCLGRVGLHTFAGLSGLRRLFLKDNGLEAIDEQSLWGLAELLELDLTANRLTHLPGRLFQGLGKLEYLLLSRNRLSALPADALGPLQRTFWLDVSHNRLQALPEAVLAPLGQLRYLSLRNNSLRTFVPQPLGLERLWLEGNPWDCGCPLRALRALALQHPAVVPRFVRAVAEGDDDRQPPAYAYNNITCASPPAVSGLDLRDLSEAHFAHC", "length": 606 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9VT44-1", "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit", "gene_name": "Dmel\\CG6749", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQTANWVLPLLLWLLCMGFPILHGADLCQPIGWRNFQCSEVASLQDLVDLGAENWHTLAIRNVQTELEVGSGENADHLANLLDLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGNPWQCPCFVKLQHWLATRDVVYLRDNTGYYKGERPLCIVTNVDYCIQNLQAVRRLGILGDFQGEQVEADAFDDDASAAQD", "length": 552 }, "evidence": [ { "id": "A0A8V0Z6E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z6E4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ], "pmid": "" }, { "name": "insulin-like growth factor ternary complex", "id": "GO:0042567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E4" } ], "pmid": "" } ] 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"MVPDCSERPKTERKTRGASRGLPSPGAAIFPRAAPRYLLHEGRHLLFLLPEGLRDAGQPQQAQGPEELPRPGSSSGRSGAQPPAAPRSPPHARRHRASAEPAEPRTGRSHLSSQRRHLSSQLPSYLARRGAPRDAARGTGAAMHAVLTVAWQRLRGAACGAGLGRGVHAGVRRLQELAEKGAEKGAESLSGTDLSPLILQRSSMRWDGKTYEEIPIAHIKATYNNTHIQVVSFDNRPFAHTSCGTEGFQNAKKGTAIAAQTAGIAAAVKARGKGVLHVRVMVKGLGPGRKAAIKGLTMGGLEVISITDNTPVPHNGCRPRKARRM", "length": 325, "header": "tr|A0A8V0Z6H7-1|A0A8V0Z6H7_CHICK Isoform 1 of Small ribosomal subunit protein uS11m OS=Gallus gallus OX=9031 GN=MRPS11 PE=1 SV=1 CANONICAL=A0A8V0Z6H7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H7/entry#A0A8V0Z6H7-1", "sequence": { "sequence": "MVPDCSERPKTERKTRGASRGLPSPGAAIFPRAAPRYLLHEGRHLLFLLPEGLRDAGQPQQAQGPEELPRPGSSSGRSGAQPPAAPRSPPHARRHRASAEPAEPRTGRSHLSSQRRHLSSQLPSYLARRGAPRDAARGTGAAMHAVLTVAWQRLRGAACGAGLGRGVHAGVRRLQELAEKGAEKGAESLSGTDLSPLILQRSSMRWDGKTYEEIPIAHIKATYNNTHIQVVSFDNRPFAHTSCGTEGFQNAKKGTAIAAQTAGIAAAVKARGKGVLHVRVMVKGLGPGRKAAIKGLTMGGLEVISITDNTPVPHNGCRPRKARRM", "length": 325, "header": "tr|A0A8V0Z6H7-1|A0A8V0Z6H7_CHICK Isoform 1 of Small ribosomal subunit protein uS11m OS=Gallus gallus OX=9031 GN=MRPS11 PE=1 SV=1 CANONICAL=A0A8V0Z6H7-1" }, "locus": { "chromosome": "10", "start_pos": 13188366, "end_pos": 13184705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048797.1", "url": "https://www.ensembl.org/id/ENSGALT00010048797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028847.1", "url": "https://www.ensembl.org/id/ENSGALP00010028847.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H7" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6I5-1", "uniprot_ac": "A0A8V0Z6I5", "uniprot_id": "A0A8V0Z6I5_CHICK", "mass": { "chemical_mass": 36524.0, "monoisotopic_mass": 36524.0 }, "refseq": { "ac": "NP_001108131", "name": "bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131" }, "gene_names": [ { "name": "JMJD7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ] }, { "name": "JMJD7-PLA2G4B", "type": "synonym", "evidence": [ { "id": "NP_001108131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131" } ] }, { "name": "JMJD7", "type": "synonym", "evidence": [ { "id": "NP_001108131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131" } ] } ], "protein_names": [ { "name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.63", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5/entry#names_and_taxonomy" } ] }, { "name": "JmjC domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5/entry#names_and_taxonomy" } ] }, { "name": "Jumonji domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5/entry#names_and_taxonomy" } ] }, { "name": "bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "type": "synonym", "evidence": [ { "id": "NP_001108131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01100551.1, SRR13267654.131524.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001108131.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131" } ] }, { "annotation": "Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as a Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5#function" }, { "database": "UniProtKB", "id": "ARBA00054742", "url": "https://www.uniprot.org/uniprotkb/ARBA00054742#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JMJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5", "locus": { "chromosome": "5", "start_pos": 24662999, "end_pos": 24656255, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020212", "url": "https://www.ensembl.org/id/ENSGALG00010020212" } ] } } ], "crossref": [ { "id": "A0A8V0Z6I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "423221", "url": "https://www.ncbi.nlm.nih.gov/gene/423221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423221", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWHDMEF", "url": "https://omabrowser.org/oma/group/YWHDMEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6I5", "url": "https://www.orthodb.org/?gene=A0A8V0Z6I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12461:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12461:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001108131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGAALRAVRGCLAAFPREARELGCVESVPYLDRPPSPLEFYREWVSPNKPCIIRNAIGHWPALRKWTLAYLREVVGHKVVSVAVTPNGYADAVFHDRFVMPEERQMPFMDFLDIVEKKVTSPSVFYVQKQCSNLTEEFPELICDVQPDIPWMSEALGKKPDAVNFWLGESAAVTSLHKDHYENLYCVISGEKRFLLHPPSDRPFIPYELYQAATYKVSEDGSFEIVDEKTAEKVPWIPLDPLNPNLERYPEYAQAKPLQCTVKAGEMLYLPSLWFHHVQQSHGCIAVNYWYDMEYDLKYSYYQLLDCLTKAMKVL", "length": 317, "header": "tr|A0A8V0Z6I5-1|A0A8V0Z6I5_CHICK Isoform 1 of Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 OS=Gallus gallus OX=9031 GN=JMJD7 PE=4 SV=1 CANONICAL=A0A8V0Z6I5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5/entry#A0A8V0Z6I5-1", "sequence": { "sequence": "MAEGAALRAVRGCLAAFPREARELGCVESVPYLDRPPSPLEFYREWVSPNKPCIIRNAIGHWPALRKWTLAYLREVVGHKVVSVAVTPNGYADAVFHDRFVMPEERQMPFMDFLDIVEKKVTSPSVFYVQKQCSNLTEEFPELICDVQPDIPWMSEALGKKPDAVNFWLGESAAVTSLHKDHYENLYCVISGEKRFLLHPPSDRPFIPYELYQAATYKVSEDGSFEIVDEKTAEKVPWIPLDPLNPNLERYPEYAQAKPLQCTVKAGEMLYLPSLWFHHVQQSHGCIAVNYWYDMEYDLKYSYYQLLDCLTKAMKVL", "length": 317, "header": "tr|A0A8V0Z6I5-1|A0A8V0Z6I5_CHICK Isoform 1 of Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 OS=Gallus gallus OX=9031 GN=JMJD7 PE=4 SV=1 CANONICAL=A0A8V0Z6I5-1" }, "locus": { "chromosome": "5", "start_pos": 24662461, "end_pos": 24656271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048807.1", "url": "https://www.ensembl.org/id/ENSGALT00010048807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028852.1", "url": "https://www.ensembl.org/id/ENSGALP00010028852.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423221", "resource": "KEGG Pathway" }, { "id": "R-GGA-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZV5-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "Jmjd7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAALDAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSFSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPVSHVLDVLEGQAQHPGVLYVQKQCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDAAAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLARYPSYSQARALHCTVRAGELLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDSLTRAAGLD", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MEH3-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "JMJD7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEAALDAVRRELREFPVAARELSVPLAVPYLDEPPSPLHFYRDWVCPNRPCIIRNALQHWPALRKWSLPYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPLSHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLPDVEPHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYELYTQATYQLTEEGSFRMVDEEAMEKVPWIPLDPLAPDLARYPSYCQAQALRCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLLDSLTKVSGLN", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H0Z2-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "Jmjd7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEAALGTVRKVLQEFPAAARDLSVPRAVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRAIVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPMSHVLDVLEGQAQHPGVLYVQKQCSNLPTELPQLLSDMESHVPWASESLGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYGLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLVRYPSYSLAHALHCTVRAGELLYLPAMWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLVDSLTRAAGLD", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0C870-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "JMJD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLYLPALWFHHVQQSQGCIAVNFWYDMEYDLKYSYFQLLDSLTKASGLD", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C872-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7", "gene_name": "Jmjd7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0WVR4-1", "protein_name": "Lysine-specific demethylase JMJ32", "gene_name": "JMJ32", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKEIENLWREVRELSLGTKIDRFDSQPSPVKFLRNYVSQSKPCVISKAITHWPALKLWSDPAYLTGALSDDVVSLHLTPNGCADAVTGDSDLCFASAHVEKVLFPEALKVVQSSCKGLKVGYLQQQNDCFRTEYSTVALDCDGDIEWATEAFGCSPEAVNLWIGTDDSVTSFHKDHYENLYAVVSGEKHFLLLPPTDVHRLYIEQYPAANYSYHRDTDAFKLEVEEPVRHVPWSSVDPYPSPEKEASERLKFPLFFDGPKPFHCTVKAGEVLYLPSMWFHHVSQTPGDGGYTIAVNYWYDMQFDIKYAYFNFLQSLLYKSSSLNPVLSWREDEDSESSDAEIAP", "length": 345 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54CS7-1", "protein_name": "JmjC domain-containing protein E", "gene_name": "jcdE", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEFIDEYDDIYSKLCQEAQDFLIIKDIERIEKPTALEFYREYVSQNKPVIITGLLENWKAYKEWSDDYLENVMKDVEVTVSITNDGLADAVKPINENDPKSERVFCKPFEKKIKFQEYIKHSKKSSKENKNKLAYYIQYQNNSLNVEYDKLLNDIDESVIDFAKEAFGSNIDATNFWMGQDKSVSSLHQDPYENMYCVVRGTKIFTLLPPIDYPFLYKSEFPSASFVNVGCDDNDENIKLEIQIDNDPKMNIPWIPVDPTETLENNIKLGYPLIERAHPITIRVEAGEVLYLPSLYFHRVAQESNKTSNSLSTIAINYWFDMKYGINYVYFQFLKETTKYQKQIKNKNKK", "length": 353 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VU77-1", "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "JMJD7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKALNWPAIGKWTPKYLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVVRRLDDPTGAVHYIQKQNSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDFVLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYARAKPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYYRMLEQMTSARSG", "length": 316 }, "evidence": [ { "id": "A0A8V0Z6I5", "url": "https://omabrowser.org/oma/group/A0A8V0Z6I5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "peptidyl-lysine 3-dioxygenase activity", "id": "GO:0106155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-9629578", "name": "JMJD7 dimer hydroxlates a lysine residue of DRG2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z6I5-1" ], "evidence": [ { "id": "R-GGA-9629578", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629578" } ] }, { "id": "R-GGA-9629591", "name": "JMJD7 dimer hydroxlates a lysine residue of DRG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z6I5-1" ], "evidence": [ { "id": "R-GGA-9629591", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629591" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z6I5", "gene_name": "JMJD7", "activity": [ { "ec_number": "1.14.11.63", "activity": "L-lysyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + succinate + CO2.", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ] }, { "ec_number": "1.14.11.63", "activity": "", "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I5" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjC", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 308, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.63", "ec_name": "L-lysyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + succinate + CO2.", "evidence": [ { "id": "1.14.11.63", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.63" }, { "id": "1.14.11.63", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.63" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6J2-1", "uniprot_ac": "A0A8V0Z6J2", "uniprot_id": "A0A8V0Z6J2_CHICK", "mass": { "chemical_mass": 10788.0, "monoisotopic_mass": 10788.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger RING-H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6J2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763:SF191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763:SF191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAVVTSCNHFFHGACLRKWLYVQDTCPMCHQHVTPAATREDGSAGPAAQPVPAHEDEVPGVGGAPARPGEDGPPPGEPLGGDGGAPGPGDAAAPELLRAAYAAW", "length": 106, "header": "tr|A0A8V0Z6J2-1|A0A8V0Z6J2_CHICK Isoform 1 of Zinc finger RING-H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6J2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J2/entry#A0A8V0Z6J2-1", "sequence": { "sequence": "MRLAVVTSCNHFFHGACLRKWLYVQDTCPMCHQHVTPAATREDGSAGPAAQPVPAHEDEVPGVGGAPARPGEDGPPPGEPLGGDGGAPGPGDAAAPELLRAAYAAW", "length": 106, "header": "tr|A0A8V0Z6J2-1|A0A8V0Z6J2_CHICK Isoform 1 of Zinc finger RING-H2-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6J2-1" }, "locus": { "chromosome": "4", "start_pos": 90444937, "end_pos": 90444206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044844.1", "url": "https://www.ensembl.org/id/ENSGALT00010044844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026766.1", "url": "https://www.ensembl.org/id/ENSGALP00010026766.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6J3-1", "uniprot_ac": "A0A8V0Z6J3", "uniprot_id": "A0A8V0Z6J3_CHICK", "mass": { "chemical_mass": 31108.0, "monoisotopic_mass": 31108.0 }, "refseq": { "ac": "NP_990120", "name": "SOUL protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990120" }, "gene_names": [ { "name": "SOUL", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J3" } ] }, { "name": "SOUL", "type": "synonym", "evidence": [ { "id": "NP_990120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990120" } ] } ], "protein_names": [ { "name": "SOUL protein", "type": "synonym", "evidence": [ { "id": "NP_990120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990120" }, { "id": "A0A8V0Z6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF117612.1, SRR13267654.213274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000217.1. On Nov 10, 2021 this sequence version replaced NP_990120.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SOUL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6J3", "locus": { "chromosome": "5", "start_pos": 58553700, "end_pos": 58542876, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018240", "url": "https://www.ensembl.org/id/ENSGALG00010018240" } ] } } ], "crossref": [ { "id": "A0A8V0Z6J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6J3", "database": 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annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507448" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMTN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M8", "locus": { "chromosome": "22", "start_pos": 1495968, "end_pos": 1510440, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020252", "url": "https://www.ensembl.org/id/ENSGALG00010020252" } ] } } ], "crossref": [ { "id": "A0A8V0Z6M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "776542", "url": "https://www.ncbi.nlm.nih.gov/gene/776542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MLEHKIY", "url": "https://omabrowser.org/oma/group/MLEHKIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6M8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040507448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507448", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVQKQPLTSPGSVCSSRGSSVPGSPSSIVAKMDNEVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLMEHVELPRSRERSLSPKSISPPPSPEMIREWLESRTPGSASQPPPRTPRSSVQHFHRPETDTTELNIYKKPPIYRQKDPHPAAPHGKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRRRMASKRGEEEEEDLTEEMKNLRELQRRELSKVTSNLGKLILKEEMEKSLPIRRKTRSLPDRTPFHTSLHMGGYKSSSLPASGRSTLTRLQSAEFSSASSEKGSPGLQNGQRGRMDRGNSLPSMLEQKIYPYEMLMVTNRGRVKLPPGVDRTRLERHLSREDFLRVFEMPPEEFGKLALWKRNELKKKAFLF", "length": 397, "header": "tr|A0A8V0Z6M8-1|A0A8V0Z6M8_CHICK Isoform 1 of Dematin OS=Gallus gallus OX=9031 GN=DMTN PE=1 SV=1 CANONICAL=A0A8V0Z6M8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M8/entry#A0A8V0Z6M8-1", "sequence": { "sequence": 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"publication": [], "pathway": [ { "id": "R-GGA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AT61-1", "protein_name": "Dematin", "gene_name": "Dmtn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERLQKQPLTSPGSVSSSRDSSVPGSPSNIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEVWAESRTLGIISQASTPRTTGTPRTSLPHFHHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF", "length": 405 }, "evidence": [ { "id": "A0A8V0Z6M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6M8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RMC1-1", "protein_name": "Dematin", "gene_name": "DMTN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERLQKQPLTSPGSVSSSRGSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWAESRSPGTFPQASAPRTTGTPRTSLPHFHHPETTRPDSNIYKKPPIYKQREPTGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLQAGTSKSSSLPAYGRTTLSRLQSTDFSPSGSETESPGLQNGEGQRGRMDRGTSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFSMSPEEFGKLALWKRNELKKKASLF", "length": 405 }, "evidence": [ { "id": "A0A8V0Z6M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6M8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08495-1", "protein_name": "Dematin", "gene_name": "DMTN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERLQKQPLTSPGSVSPSRDSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF", "length": 405 }, "evidence": [ { "id": "A0A8V0Z6M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z6M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV69-1", "protein_name": "Dematin", "gene_name": "Dmtn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"tr|A0A8V0Z6N9-1|A0A8V0Z6N9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6N9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6N9/entry#A0A8V0Z6N9-1", "sequence": { "sequence": "AAARPEGSAHRGRGGAGAGAGRAVVPLQGAARGLGERPAVLPQTGPGLPVRGAVLPRPPLPGRRAGGQRAAQRQRAAAVGAAAPRRRPARLRAQLLLGRHLHALPLRQRGAGRRLPRLPAARGARQRAIPPLSAAPLRAAAPRAARPLRGVPRGAGRHAGHRRGHDGRGGLHLRHAGLHLPAGGLHHREPDEPRRAAATAERPPAPQLCDPKALKSNVGVVVLPEQQGCGTGCPQQHPAAPNYE", "length": 244, "header": "tr|A0A8V0Z6N9-1|A0A8V0Z6N9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6N9-1" }, "locus": { "chromosome": "21", "start_pos": 2108280, "end_pos": 2106990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048895.1", "url": "https://www.ensembl.org/id/ENSGALT00010048895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028902.1", "url": 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"McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339" }, "gene_names": [ { "name": "MKKS", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ] }, { "name": "MKKS", "type": "synonym", "evidence": [ { "id": "NP_001186339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339" } ] } ], "protein_names": [ { "name": "Molecular chaperone MKKS", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0/entry#names_and_taxonomy" } ] }, { "name": "McKusick-Kaufman syndrome protein", "type": "synonym", "evidence": [ { "id": "NP_001186339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339" } ] }, { "name": "McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin", "type": "synonym", "evidence": [ { "id": "NP_001186339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339" }, { "id": "A0A8V0Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.13572.1, SRR13267652.18551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001186339.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339" } ] }, { "annotation": "Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0#function" }, { "database": "UniProtKB", "id": "ARBA00059081", "url": "https://www.uniprot.org/uniprotkb/ARBA00059081#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MKKS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0", "locus": { "chromosome": "3", "start_pos": 13319363, "end_pos": 13314605, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018287", "url": "https://www.ensembl.org/id/ENSGALG00010018287" } ] } } ], "crossref": [ { "id": "A0A8V0Z6P0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6P0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416737", "url": "https://www.ncbi.nlm.nih.gov/gene/416737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416737", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416737", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFVCQKV", "url": "https://omabrowser.org/oma/group/LFVCQKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6P0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46787", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46787", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46787:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46787:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRLEAKKPSLFISEPLTTVSQPLSLLIAILKSCYGPAGRLKQLHNGVGGYVCLTSQSSAILGHLSVSHPVLKVLTASVQNHVSRFSDCGLFTAILCCSLIENFKNLNIASCTIIKISKHLLSLCTDYLKSKACGCQVSVDFSNLETLLCLVRSILTSKPACMLNKTEVDCLAVLIVKAFMYTVPCHPETKPVLGKCVTVPLKGKRVLDSTVIPGLLIETPEIQFAKPFSVKRTSSDAVKVVVFCVSMSGDLFDPEEGTVTVHHKISLEMSELDQLLNVGKQLVNDEVGLVVCQKVIHPSLKQYLKDNHIIAVDRAGLSVMEPLSQVTGSKPIASIYSLSPSCYGSLKDVRAESFASKHFVHLIPNDTTVCSLILCNRNETTWDELKRACETAEHVLQLTLKEPLALLGGGCTETHLASYLRQKTCCLSTSSSKDVECSPTQYQLITDAFCHSLESVACSLSHDGGEILTDMAYGHCWLVPSGFPSASNWSDLLSKCGCGINSSTKDLNWRHLQPLFGSSPIESCPKEPSGKVTDFMTLDCFAAKYNGLQVAVETANLILDLSCVIEDQN", "length": 570, "header": "tr|A0A8V0Z6P0-1|A0A8V0Z6P0_CHICK Isoform 1 of Molecular chaperone MKKS OS=Gallus gallus OX=9031 GN=MKKS PE=3 SV=1 CANONICAL=A0A8V0Z6P0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0/entry#A0A8V0Z6P0-1", "sequence": { "sequence": "MSRLEAKKPSLFISEPLTTVSQPLSLLIAILKSCYGPAGRLKQLHNGVGGYVCLTSQSSAILGHLSVSHPVLKVLTASVQNHVSRFSDCGLFTAILCCSLIENFKNLNIASCTIIKISKHLLSLCTDYLKSKACGCQVSVDFSNLETLLCLVRSILTSKPACMLNKTEVDCLAVLIVKAFMYTVPCHPETKPVLGKCVTVPLKGKRVLDSTVIPGLLIETPEIQFAKPFSVKRTSSDAVKVVVFCVSMSGDLFDPEEGTVTVHHKISLEMSELDQLLNVGKQLVNDEVGLVVCQKVIHPSLKQYLKDNHIIAVDRAGLSVMEPLSQVTGSKPIASIYSLSPSCYGSLKDVRAESFASKHFVHLIPNDTTVCSLILCNRNETTWDELKRACETAEHVLQLTLKEPLALLGGGCTETHLASYLRQKTCCLSTSSSKDVECSPTQYQLITDAFCHSLESVACSLSHDGGEILTDMAYGHCWLVPSGFPSASNWSDLLSKCGCGINSSTKDLNWRHLQPLFGSSPIESCPKEPSGKVTDFMTLDCFAAKYNGLQVAVETANLILDLSCVIEDQN", "length": 570, "header": "tr|A0A8V0Z6P0-1|A0A8V0Z6P0_CHICK Isoform 1 of Molecular chaperone MKKS OS=Gallus gallus OX=9031 GN=MKKS PE=3 SV=1 CANONICAL=A0A8V0Z6P0-1" }, "locus": { "chromosome": "3", "start_pos": 13318359, "end_pos": 13315027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044132.1", "url": "https://www.ensembl.org/id/ENSGALT00010044132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026240.1", "url": "https://www.ensembl.org/id/ENSGALP00010026240.1" } ] } }, { "isoform_ac": "A0A8V0Z6P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0/entry#A0A8V0Z6P4-1", "sequence": { "sequence": "MSRLEAKKPSLFISEPLTTVSQPLSLLIAILKSCYGPAGRLKQLHNGVGGYVCLTSQSSAILGHLSVSHPVLKVLTASVQNHVSRFSDCGLFTAILCCSLIENFKNLNIASCTIIKISKHLLSLCTDYLKSKACGCQVSVDFSNLETLLCLVRSILTSKPACMLNKTEVDCLAVLIVKAFMYTVPCHPETKPVLGKCVTVPLKGKRVLDSTVIPGLLIETPEIQFAKPFSVKRTSSDAVKVVVFCVSMSGDLFDPEEGTVTVHHKISLEMSELDQLLNVGKQLVNDEVGLVVCQKVIHPSLKQYLKDNHIIAVDRAGLSVMEPLSQVTGSKPIASIYSLSPSCYGSLKDVRAESFASKHFVHLIPNDTTVCSLILCNRNETTWDELKTCCLSTSSSKDVECSPTQYQLITDAFCHSLESVACSLSHDGGEILTDMAYGHCWLVPSGFPSASNWSDLLSKCGCGINSSTKDLNWRHLQPLFGSSPIESCPKEPSGKVTDFMTLDCFAAKYNGLQVAVETANLILDLSCVIEDQN", "length": 533, "header": "tr|A0A8V0Z6P4-1|A0A8V0Z6P4_CHICK Computationally mapped isoform of Molecular chaperone MKKS OS=Gallus gallus OX=9031 GN=MKKS PE=3 SV=1 CANONICAL=A0A8V0Z6P0-1" }, "locus": { "chromosome": "3", "start_pos": 13318359, "end_pos": 13315027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044138.1", "url": "https://www.ensembl.org/id/ENSGALT00010044138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026245.1", "url": "https://www.ensembl.org/id/ENSGALP00010026245.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416737", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416737", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HEF6-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "Mkks", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRFEAKKPSLCKAEPLTSEKVRSTLSVLKGILASCYGPSGRLKQLHNGLGGCVCTTSQSSALLRNLSVTHPVLKVLTASVQNHVSCFGDCGLFTAILCCNLIENIQRIGLTPTKVTKLNKYLLGLCTSYLKSEACSCRIPVDLSSTHIFLGLVHSVLTSKPACMLNKKEADHISALILKAFLLTIPESAEDRVILGKSIIVPLKGQRVTDSTVLPGLLIEMSEVQLRRLSLTQKSSALKVALFCVSLSGDFSNAGEGTVVVSCQVSLENAVLEQLLNLGRQLVGDQVDLVLCQKVIHPSLKQFLSEHHIIAIDRVGVTLMEPLSKVTGAMPIGSLNTIPSTAYGSVKDLCSARFGSKHFFHLIPNEATVCSLLLCSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYIRHKIHNQTEDIVRDDGYSQAELQIATEAFCSALESVAGSLEHDGGEILLDMKYGHFWSGPSASASVVNWPDMLSRCRCGLYNSQEGLSWSFLRSTYHPFAPQTCLSQAAVGAASNLTVDCFTAKLSGLQVAVETANLILDLSYVIEDKN", "length": 570 }, "evidence": [ { "id": "A0A8V0Z6P0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6P0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BNU6-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLEAKKPSICRSDPLTGERARASLAALKGLVMSCYGPAGRLKQLHNGRGGSVVTTSQSAALLAGLPVSHPVLKVLTAAVRNHVACFSDGGLFTAILCCNLVENVQRLGLAPTTVIKLNKHLLSLCTSYLKSEGCACRIPVDFSSTQILLSLVRSILTSKPACMLIAKEVDHISTLILRAFLLTIPENAQEHIILGKSIIVPLKGQRVIDSAVLPGILIEVSEVQLMKILPIKKSDSFKVALFCVSLSGDLSDTGEGTLLVSYGVSLENAALDQLFNLGKQLVSDHVDLVLCQKVIHPSLKQFLRTHHVIAVDRIGVSLMEPLSKVTGTWPIGSLGSISPSSYGSVKDLCIAKFGCKHFFHLIPNKTTICSLLLCNRNDTAWDELKLTCQTALHALQLTIKDPYALLGGGCTETHLVAYIRHKTRNEPESVLRDERCSQTELQLITEAFCSALESLAGSLEHDGGEILTDSKYGHFWSVQANLPSAVNWPDLPSRCGCGLYSSQEELSWSFLRSARHPFPPQTCLSREATGSADTLTLDCFTAKLSGLQVAVETASLILDLSCVIEDTN", "length": 570 }, "evidence": [ { "id": "A0A8V0Z6P0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6P0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SBK4-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRLEAKRPSLCKSEPLTSERVKATLSVLKGVVTSCYGPAGRLKQLHNGRGGSVCTTSQSAALLASLPVTQPILKILTTSVQNHVSCFSDCGLFTAILCCNLVEKVQGVGLTTTTAIKLNKHLLSLCTEYLKSEICGCRIPIDFGSTQLLLCLVRSLLTSKPACMLTREEVEHISTLILRAFLLTVPENAKDRIILGKSIIVPLKGQRVIDSTVLPGVLIEIPEVQVMKILPIKKSDSFKVALFCASLSGDLSETGEGTVVLSHGVSLENAVLDQLLNLGRQLVSDQVDLVMCQKVIHPSLKQFLRTHGVIAMDRVGVALMEPLSKMTGTQPIGSLNSVSPSSYGSVKDWCTAKFGFKHFFHLIPNETTVCSLLLCNRNDTAWDELKLTCQTALHALQLTIKEPYVLLGGGCTETHLAAYIRHKTRDEPESILKGDGCTQTELQLMSEAFCSALETLAGSLEHDGGEILTDRKYGHFWSVQADSPSAVNWPDLLSRCGCGLYSSQEELGWCFLRGAHHPFMPQTCLPREASGSANDLTLDCFTAKLSGLQVAVETANLILDLSYVIEDRN", "length": 570 }, "evidence": [ { "id": "A0A8V0Z6P0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6P0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JI70-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "Mkks", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRLEAKKPSLCKTEPLTSEKVRSTLSVLKGVIASCYGPSGRLKQLHNGLGGCVYTTSQSSALLRNLSVTHPVLKILTSSVQNHVSCFSDCGLFTAILCCNLIENIQRLDLTPATAIKLNKYLLSLCTSYLKSEACSCRIPVDFRSTHTFLSLVHSILTSKPACMLTRKETDHIGALILKAFLLTIPESTEERMVLGKSIIVPLKGQRVTDSTVLPGLLIEASEVQLRRLLPTQKASGLRVALFCTSLSGDFSNAGEGVVVAHYQVSLENAVLEQLLNLGRRLVTDHVDLVLCQKVIHPSLKQFFSERHVMAIDRVGVTLMESLSKVTGATPIGSLNPIVSTTYGSVKDVCSARFGSKHFFHLLPNEATVCTLLLCSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYVRHKVHHEAEAIVRDDGCTQAKLHVAAEAFCSALESVAGSLEHDGGEILIDTKYGHLWSCQADSASVGNWSDTLSRCGCGLYNSQEELSWSVLRSTYHPFAPQTCLPQAALGSASNLTVDCFTAKLSGLQVAVETANLILDLSYVIEDKN", "length": 570 }, "evidence": [ { "id": "A0A8V0Z6P0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6P0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NPJ1-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVIEDKN", "length": 570 }, "evidence": [ { "id": "A0A8V0Z6P0", "url": "https://omabrowser.org/oma/group/A0A8V0Z6P0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "developmental process involved in reproduction", "id": "GO:0003006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "negative regulation of appetite by leptin-mediated signaling pathway", "id": "GO:0038108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038108", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "kinociliary basal body", "id": "GO:1902636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902636", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P0" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6P0", "url": 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"MAGSPALLLLLSLGLCCTITQGQKNTMEARFLNRNIKHPIEGQRLELECLHYERNRPIFWIRLDKSENLHFLASSTRSYSTTLQEGEKTSPNFEALWRGNSYRLLVKSFRAQDEGIYFCINYINPVLHFSSGQPAFFPGQTLQMTPGAGIFLFLLSPLSFLPAGTSNENTLHFCYDVVIWVNLAGACLLLLTAITITITHCQKTINRQCHCKQKL", "length": 215, "header": "tr|A0A8V0Z6S0-1|A0A8V0Z6S0_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6S0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0/entry#A0A8V0Z6S0-1", "sequence": { "sequence": "MAGSPALLLLLSLGLCCTITQGQKNTMEARFLNRNIKHPIEGQRLELECLHYERNRPIFWIRLDKSENLHFLASSTRSYSTTLQEGEKTSPNFEALWRGNSYRLLVKSFRAQDEGIYFCINYINPVLHFSSGQPAFFPGQTLQMTPGAGIFLFLLSPLSFLPAGTSNENTLHFCYDVVIWVNLAGACLLLLTAITITITHCQKTINRQCHCKQKL", "length": 215, "header": "tr|A0A8V0Z6S0-1|A0A8V0Z6S0_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6S0-1" }, "locus": { "chromosome": "4", "start_pos": 85236038, "end_pos": 85233440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041301.1", "url": "https://www.ensembl.org/id/ENSGALT00010041301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024186.1", "url": "https://www.ensembl.org/id/ENSGALP00010024186.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0" } ], "pmid": "" }, { "name": "T cell mediated immunity", "id": "GO:0002456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0" } ], "pmid": "" }, { "name": "cytotoxic T cell differentiation", "id": "GO:0045065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 119, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7C1-1", "uniprot_ac": "A0A8V0Z7C1", "uniprot_id": "A0A8V0Z7C1_CHICK", "mass": { "chemical_mass": 52962.0, "monoisotopic_mass": 52962.0 }, "refseq": {}, "gene_names": [ { "name": "NARFL", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ] } ], "protein_names": [ { "name": "Nuclear prelamin A recognition factor-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NARFL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1", "locus": { "chromosome": "14", "start_pos": 6042317, "end_pos": 6029275, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018577", "url": "https://www.ensembl.org/id/ENSGALG00010018577" } ] } } ], "crossref": [ { "id": "A0A8V0Z7C1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6S3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7C1", "url": "https://www.orthodb.org/?gene=A0A8V0Z7C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE67", "url": "https://www.orthodb.org/?gene=A0A8V0ZE67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPFSGVLQLTDLDDYIGPSQECIKPVKVEKKPGKAAAKIKIEADGSYFQITQDGEAQKLEKAKITLNDCLACSGCITSAESVLITQQSHEEFYKTLAFNKTAAPNEQKLVVVSVSPQSRASLAAKCKMSILETAKKLTAFLKSQGVHYVFDTTFSRNFSLLESQKEFVKRFRKQSEDKKALPMLASACPGWICYAEKTHGSFIIPYISTTKSPQQIMGSLIKGHFAEQQHLTPNKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVITTGEVLKLLEQERVSLPDVDPAPLDTISATEEELTGHSGGGSGGYLEHIYKYAAKELFGIEVDTIQYKPLKNKDFQEVTLEKDGVVLLQFALAYGFRNIQNLVQKLKRGKSPYHYVEVMACPSGCLNGGGQIKVESESSKDWLQQVEKLYESLKTETPEENWTVTALYEQWLGGPESEKARKALHTEYHAVEKASAGFNIKW", "length": 474, "header": "tr|A0A8V0Z7C1-1|A0A8V0Z7C1_CHICK Isoform 1 of Nuclear prelamin A recognition factor-like protein OS=Gallus gallus OX=9031 GN=NARFL PE=1 SV=1 CANONICAL=A0A8V0Z7C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1/entry#A0A8V0Z6S3-1", "sequence": { "sequence": "MMLKKCSFCKKGECIKPVKVEKKPGKAAAKIKIEADGSYFQITQDGEAQKLEKAKITLNDCLACSGCITSAESVLITQQSHEEFYKTLAFNKTAAPNEQKLVVVSVSPQSRASLAAKCKMSILETAKKLTAFLKSQGVHYVFDTTFSRNFSLLESQKEFVKRFRKQSEDKKALPMLASACPGWICYAEKTHGSFIIPYISTTKSPQQIMGSLIKGHFAEQQHLTPNKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVITTGEVLKLLEQERVSLPDVDPAPLDTMFSSATEEELTGHSGGGSGGYLEHIYKYAAKELFGIEVDTIQYKPLKNKDFQEVTLEKDGVVLLQFALAYGFRNIQNLVQKLKRGKSPYHYVEVMACPSGCLNGGGQIKVESESSKDWLQQVEKLYESLKTETPEENWTVTALYEQWLGGPESEKARKALHTEYHAVEKASAGFNIKW", "length": 466, "header": "tr|A0A8V0Z6S3-1|A0A8V0Z7C1_CHICK Computationally mapped isoform of Nuclear prelamin A recognition factor-like protein OS=Gallus gallus OX=9031 GN=NARFL PE=1 SV=1 CANONICAL=A0A8V0Z7C1-1" }, "locus": { "chromosome": "14", "start_pos": 6040705, "end_pos": 6030468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044957.1", "url": "https://www.ensembl.org/id/ENSGALT00010044957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026849.1", "url": "https://www.ensembl.org/id/ENSGALP00010026849.1" } ] } }, { "isoform_ac": "A0A8V0Z7C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1/entry#A0A8V0Z7C1-1", "sequence": { "sequence": "MASPFSGVLQLTDLDDYIGPSQECIKPVKVEKKPGKAAAKIKIEADGSYFQITQDGEAQKLEKAKITLNDCLACSGCITSAESVLITQQSHEEFYKTLAFNKTAAPNEQKLVVVSVSPQSRASLAAKCKMSILETAKKLTAFLKSQGVHYVFDTTFSRNFSLLESQKEFVKRFRKQSEDKKALPMLASACPGWICYAEKTHGSFIIPYISTTKSPQQIMGSLIKGHFAEQQHLTPNKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVITTGEVLKLLEQERVSLPDVDPAPLDTISATEEELTGHSGGGSGGYLEHIYKYAAKELFGIEVDTIQYKPLKNKDFQEVTLEKDGVVLLQFALAYGFRNIQNLVQKLKRGKSPYHYVEVMACPSGCLNGGGQIKVESESSKDWLQQVEKLYESLKTETPEENWTVTALYEQWLGGPESEKARKALHTEYHAVEKASAGFNIKW", "length": 474, "header": "tr|A0A8V0Z7C1-1|A0A8V0Z7C1_CHICK Isoform 1 of Nuclear prelamin A recognition factor-like protein OS=Gallus gallus OX=9031 GN=NARFL PE=1 SV=1 CANONICAL=A0A8V0Z7C1-1" }, "locus": { "chromosome": "14", "start_pos": 6040705, "end_pos": 6029299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044959.1", "url": "https://www.ensembl.org/id/ENSGALT00010044959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026851.1", "url": "https://www.ensembl.org/id/ENSGALP00010026851.1" } ] } }, { "isoform_ac": "A0A8V0Z8B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1/entry#A0A8V0Z8B7-1", "sequence": { "sequence": "MASPFSGVLQLTDLDDYIGPSQECIKPVKVEKKPGKAAAKIKIEADGSYFQITQDGEAQKLEKAKITLNDCLACSGCITSAESVLITQQSHEEFYKTLAFNKTAAPNEQKLVVVSVSPQSRASLAAKCKMSILETAKKLTAFLKSQGWICYAEKTHGSFIIPYISTTKSPQQIMGSLIKGHFAEQQHLTPNKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVITTGEVLKLLEQERVSLPDVDPAPLDTMFSSATEEELTGHSGGGSGGYLEHIYKYAAKELFGIEVDTIQYKPLKNKDFQEVTLEKDGVVLLQFALAYGFRNIQNLVQKLKRGKSPYHYVEVMACPSGCLNGGGQIKVESESSKDWLQQVEKLYESLKTETPEENWTVTALYEQWLGGPESEKARKALHTEYHAVEKASAGFNIKW", "length": 431, "header": "tr|A0A8V0Z8B7-1|A0A8V0Z8B7_CHICK Computationally mapped isoform of Nuclear prelamin A recognition factor OS=Gallus gallus OX=9031 GN=NARFL PE=1 SV=1 CANONICAL=A0A8V0Z7C1-1" }, "locus": { "chromosome": "14", "start_pos": 6040705, "end_pos": 6029299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044963.1", "url": "https://www.ensembl.org/id/ENSGALT00010044963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026855.1", "url": "https://www.ensembl.org/id/ENSGALP00010026855.1" } ] } }, { "isoform_ac": "A0A8V0ZE67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1/entry#A0A8V0ZE67-1", "sequence": { "sequence": "MASPFSGVLQLTDLDDYIGPSQECIKPVKVEKKPGKAAAKIKIEADGSYFQITQDGEAQKLEKAKITLNDCLACSGCITSAESVLITQQSHEEFYKTLAFNKTAAPNEQKLVVVSVSPQSRASLAAKCKMSILETAKKLTAFLKSQGVHYVFDTTFSRNFSLLESQKEFVKRFRKQSEDKKALPMLASACPGWICYAEKTHGSFIIPYISTTKSPQQIMGSLIKGHFAEQQHLTPNKIYHVTVMPCYDKKLEASRPDFFNQEYQTRDVDCVITTGEVLKLLEQERVSLPDVDPAPLDTMFSSATEEELTGHSGGGSGGYLEHIYKNKDFQEVTLEKDGVVLLQFALAYGFRNIQNLVQKLKRGKSPYHYVEVMACPSGCLNGGGQIKVESESSKDWLQQVEKLYESLKTETPEENWTVTALYEQWLGGPESEKARKALHTEYHAVEKASAGFNIKW", "length": 456, "header": "tr|A0A8V0ZE67-1|A0A8V0ZE67_CHICK Computationally mapped isoform of Nuclear prelamin A recognition factor like OS=Gallus gallus OX=9031 GN=NARFL PE=1 SV=1 CANONICAL=A0A8V0Z7C1-1" }, "locus": { "chromosome": "14", "start_pos": 6040705, "end_pos": 6029299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044961.1", "url": "https://www.ensembl.org/id/ENSGALT00010044961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026853.1", "url": "https://www.ensembl.org/id/ENSGALP00010026853.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7C1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7C1", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAEFASEDRAGDTVSGDTERYASSAIDRQGSTSMRKSFHYASLRVKSRKWSKGSSLTSGSRRRISCKDLGHGDCEGWLWKKKDAKGYFTQKWKKYWFILKDSSLYWYTNQNDEKAEGFISLPEFRIDRAIECRKKHAFKACHPKIKSFYFATDCLEEMNRWMNRLGLAAIGYTPDDKDIHPDEDYWSESDQDDVDGSLTLKQEGSSTLCDTYHRTPSVTSSSPFPEAKHGRHFSSESTYSHSSAEDSRQDVAGSTHSSGCRPPYRERRSWQDLIETPLTSSGLHFLQTVPPDPEYVSGQPGMSPERRRQATLPVQRRHNYEQDGPFPLVECQRGHSSHSRPQKQRSQSLPRNRDVRGKGHVKSIEGTEDNLEEKIPIRRHNSFCAEESIKETGENLDGLQELYKSLEQASLSAFGEQRPSTKQEFRKSFVKRCNDPVINEKLHHIRVLKSTLKAKEGDLTVINSLLDDPNLTSKKFKDWKLKNYEFFLDICEYSAALKSQNGASELATSAPMLTHTHSFIETHV", "length": 526, "header": "tr|A0A8V0Z6U5-1|A0A8V0Z6U5_CHICK Isoform 1 of PH domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6U5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U5/entry#A0A8V0Z6U5-1", "sequence": { "sequence": "MPAAEFASEDRAGDTVSGDTERYASSAIDRQGSTSMRKSFHYASLRVKSRKWSKGSSLTSGSRRRISCKDLGHGDCEGWLWKKKDAKGYFTQKWKKYWFILKDSSLYWYTNQNDEKAEGFISLPEFRIDRAIECRKKHAFKACHPKIKSFYFATDCLEEMNRWMNRLGLAAIGYTPDDKDIHPDEDYWSESDQDDVDGSLTLKQEGSSTLCDTYHRTPSVTSSSPFPEAKHGRHFSSESTYSHSSAEDSRQDVAGSTHSSGCRPPYRERRSWQDLIETPLTSSGLHFLQTVPPDPEYVSGQPGMSPERRRQATLPVQRRHNYEQDGPFPLVECQRGHSSHSRPQKQRSQSLPRNRDVRGKGHVKSIEGTEDNLEEKIPIRRHNSFCAEESIKETGENLDGLQELYKSLEQASLSAFGEQRPSTKQEFRKSFVKRCNDPVINEKLHHIRVLKSTLKAKEGDLTVINSLLDDPNLTSKKFKDWKLKNYEFFLDICEYSAALKSQNGASELATSAPMLTHTHSFIETHV", "length": 526, "header": "tr|A0A8V0Z6U5-1|A0A8V0Z6U5_CHICK Isoform 1 of PH domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6U5-1" }, "locus": { "chromosome": "4", "start_pos": 8731639, "end_pos": 8698383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044219.1", "url": "https://www.ensembl.org/id/ENSGALT00010044219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026302.1", "url": "https://www.ensembl.org/id/ENSGALP00010026302.1" } ] } }, { "isoform_ac": "A0A8V0ZCQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U5/entry#A0A8V0ZCQ7-1", "sequence": { "sequence": "MKLQRAGDTVSGDTERYASSAIDRQGSTSMRKSFHYASLRVKSRKWSKGSSLTSGSRRRISCKDLGHGDCEGWLWKKKDAKGYFTQKWKKYWFILKDSSLYWYTNQNDEKAEGFISLPEFRIDRAIECRKKHAFKACHPKIKSFYFATDCLEEMNRWMNRLGLAAIGYTPDDKDIHPDEADYWSESDQDDVDGSLTLKQEGSSTLCDTYHRTPSVTSSSPFPEAKHGRHFSSESTYSHSSAEDSRQDVAGSTHSSGCRPPYRERRSWQDLIETPLTSSGLHFLQTVPPDPEYVSGQPGMSPERRRQATLPVQRRHNYEQDGPFPLVECQRGHSSHSRPQKQRSQSLPRNRDVRGKGHVKSIEGTEDNLEEKIPIRRHNSFCAEESIKETGENLDGLQELYKSLEQASLSAFGEQRPSTKQEFRKSFVKRCNDPVINEKLHHIRVLKSTLKAKEGDLTVINSLLDDPNLTSKKFKDWKLKNYEFFLDICEYSAALKSQNGASELATSAPMLTHTHSFIETHV", "length": 521, "header": "tr|A0A8V0ZCQ7-1|A0A8V0ZCQ7_CHICK Computationally mapped isoform of PH domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6U5-1" }, "locus": { "chromosome": "4", "start_pos": 8734494, "end_pos": 8698383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044223.1", "url": "https://www.ensembl.org/id/ENSGALT00010044223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026305.1", "url": "https://www.ensembl.org/id/ENSGALP00010026305.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 172, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 472, "end_pos": 474 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6V1-1", "uniprot_ac": "A0A8V0Z6V1", "uniprot_id": "A0A8V0Z6V1_CHICK", "mass": { "chemical_mass": 37455.0, "monoisotopic_mass": 37455.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6V1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6V1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6U6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCALWLPYGVPHAVPYGCPMCALWLPCVLPYGVPHAVPYWDPLCVPYDCPMAALWLPYGVPHAVPYGVPLWVAPRLPHSPIAPQVSAAREEVPIGCPIAALWLPYGCPMCALWLPYGCPMCALWLPIAPQVSAAREEVPGRRGFPGYMYTDLASIYERAGRVGGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGDLSNQLYACYAIGKDVQAMKAVVGEEALSADDLLYLEFLHKFERHFIAQGPYENRSVFESLELGWQLLRTFPRQMLKRIPDDVLDEFYPREGRAGGGTAL", "length": 337, "header": "tr|A0A8V0Z6V1-1|A0A8V0Z6V1_CHICK Isoform 1 of ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z6V1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1/entry#A0A8V0Z6U6-1", "sequence": { "sequence": "MCSPMCALWLPYVPIAPQVSAAREEVPGRRGFPGYMYTDLASIYERAGRVGGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGDLSNQLYACYAIGKDVQAMKAVVGEEALSADDLLYLEFLHKFERHFIAQGPYENRSVFESLELGWQLLRTFPRQMLKRIPDDVLDEFYPREGRAGGGTAL", "length": 225, "header": "tr|A0A8V0Z6U6-1|A0A8V0Z6V1_CHICK Computationally mapped isoform of ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z6V1-1" }, "locus": { "chromosome": "4", "start_pos": 90326569, "end_pos": 90309496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044745.1", "url": "https://www.ensembl.org/id/ENSGALT00010044745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026667.1", "url": "https://www.ensembl.org/id/ENSGALP00010026667.1" } ] } }, { "isoform_ac": "A0A8V0Z6V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1/entry#A0A8V0Z6V1-1", "sequence": { "sequence": "MCALWLPYGVPHAVPYGCPMCALWLPCVLPYGVPHAVPYWDPLCVPYDCPMAALWLPYGVPHAVPYGVPLWVAPRLPHSPIAPQVSAAREEVPIGCPIAALWLPYGCPMCALWLPYGCPMCALWLPIAPQVSAAREEVPGRRGFPGYMYTDLASIYERAGRVGGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGDLSNQLYACYAIGKDVQAMKAVVGEEALSADDLLYLEFLHKFERHFIAQGPYENRSVFESLELGWQLLRTFPRQMLKRIPDDVLDEFYPREGRAGGGTAL", "length": 337, "header": "tr|A0A8V0Z6V1-1|A0A8V0Z6V1_CHICK Isoform 1 of ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z6V1-1" }, "locus": { "chromosome": "4", "start_pos": 90327154, "end_pos": 90309496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044750.1", "url": "https://www.ensembl.org/id/ENSGALT00010044750.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026672.1", "url": "https://www.ensembl.org/id/ENSGALP00010026672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1" }, { "id": "PF22919", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATP synthase A/B type C-terminal", "eco_id": "ECO_0000259", "start_pos": 226, "end_pos": 325, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z6V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V1" }, { "id": "PF00006", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 220, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015156861.2. 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SRR13267649.22989.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA103992482 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001186629.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7", "locus": { "chromosome": "5", "start_pos": 27627872, "end_pos": 27637377, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020303", "url": "https://www.ensembl.org/id/ENSGALG00010020303" } ] } } ], "crossref": [ { "id": "A0A8V0Z6W7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6W7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423264", "url": "https://www.ncbi.nlm.nih.gov/gene/423264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423264", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYYQTPK", "url": "https://omabrowser.org/oma/group/RYYQTPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6W7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13620:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13620:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRQAAVPVALAALLGIAAGGLVLWKAAQRRRGRARSGSLREEAAGERPEGKASEAGGREALPLFAPPTLSWVERSLGADIVVVSERQEWDRVQPLLKKELEKWPVLGMDCEWVSVEGKANPVSLLQMASASGLCVLVRLPRLVASGQPVPKTLLDIMADDAVLKVGVGCWEDACKLLQDYSLPVKGSVDLRYLAMRQRKDLLHNCLSLKSLAEKVLNCPLDKSPHMRCSNWEAEELTQDQVLYAARDAQVSVALFLHLLGFACLPATSKGENSVSGWEKVLSKCQGLVDIPFKGRKSGSTGEDRSGEARSPHKGKNRRSVVNVHSSGSQQVRDPRRQKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRKKAQWYLDKGIGDLVSTDPFVVKLRFEPSGRPESDVDYYLMVKENLCVVCGKRESYIRKNIVPHEYRRHFPIQMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAEEFGAPIGSEEGVRLLEDPLRRQVRSGARALLNADSLPDPRKAELLQGIKDFFNVEAVTPEMLQEAAGLETRICNESYMPHGLKVVQCCAKGGLRSLMQLERRWRQHFLDSMQPKHLPEQWSVDHNHTKLIRKYGEDLQIQLS", "length": 621, "header": "tr|A0A8V0Z6W7-1|A0A8V0Z6W7_CHICK Isoform 1 of Exonuclease 3'-5' domain-containing protein 2 OS=Gallus gallus OX=9031 GN=EXD2 PE=1 SV=1 CANONICAL=A0A8V0Z6W7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7/entry#A0A8V0Z6W7-1", "sequence": { "sequence": "MPRQAAVPVALAALLGIAAGGLVLWKAAQRRRGRARSGSLREEAAGERPEGKASEAGGREALPLFAPPTLSWVERSLGADIVVVSERQEWDRVQPLLKKELEKWPVLGMDCEWVSVEGKANPVSLLQMASASGLCVLVRLPRLVASGQPVPKTLLDIMADDAVLKVGVGCWEDACKLLQDYSLPVKGSVDLRYLAMRQRKDLLHNCLSLKSLAEKVLNCPLDKSPHMRCSNWEAEELTQDQVLYAARDAQVSVALFLHLLGFACLPATSKGENSVSGWEKVLSKCQGLVDIPFKGRKSGSTGEDRSGEARSPHKGKNRRSVVNVHSSGSQQVRDPRRQKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRKKAQWYLDKGIGDLVSTDPFVVKLRFEPSGRPESDVDYYLMVKENLCVVCGKRESYIRKNIVPHEYRRHFPIQMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAEEFGAPIGSEEGVRLLEDPLRRQVRSGARALLNADSLPDPRKAELLQGIKDFFNVEAVTPEMLQEAAGLETRICNESYMPHGLKVVQCCAKGGLRSLMQLERRWRQHFLDSMQPKHLPEQWSVDHNHTKLIRKYGEDLQIQLS", "length": 621, "header": "tr|A0A8V0Z6W7-1|A0A8V0Z6W7_CHICK Isoform 1 of Exonuclease 3'-5' domain-containing protein 2 OS=Gallus gallus OX=9031 GN=EXD2 PE=1 SV=1 CANONICAL=A0A8V0Z6W7-1" }, "locus": { "chromosome": "5", "start_pos": 27636874, "end_pos": 27629022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049003.1", "url": "https://www.ensembl.org/id/ENSGALT00010049003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028973.1", "url": "https://www.ensembl.org/id/ENSGALP00010028973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A1J1-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "EXD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQVAKEVPVLQREVPQVFQSSPGPQIVGLVICFPSTAEKLKMSKHLVALTVTTLLGVAVGGFVLWKGIQRRRNKTSHVTRQQLPPPPQPKAPGRGELPAPEEDQPHSSAPRASWEERILKAKVVTVSQEEEWDQIEPLLRRELKDFPVLGIDCEWVNLEGKASPLSLLQMASPSGFCVLVRLPKLISGGKTLPKTLLDILADGTILKVGVGCSEDASKLLQDYGLIVKGCLDLRYLAMRHRNNLLSNGLSLKSLAETVLNFPLDKSLLLRCSNWDAENLTEDQVIYAARDAQISVALFLRLLGYPFSRNSTPEENNDRIGWRKVLEKCQDVVDVPFRSKGISRSGEEVHGEAAEAPQKPRNKKSKTDGAMPGTHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEDPFVVKLQFEPAGRPESPGDYYLMVKENLCVVCGKKDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYHDNHLKQQLAREFQAPIGSEEGLRLLEDPERRQVRSGARALLTAESLPAHRKEELLQALREFYHTHSVTEQMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPRHLPQQWSVDHNHQKLLRKYGEDLPIKLS", "length": 665 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TA89-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "EXD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSKHLVALTVTTLLGVAVGGFVLWKGFQRRRSKSSPVTRRRLSQQQQQQQQQQVPGGRELPAPGEDQPHSIAPRASWEERILGAKVMTVSQEAEWDQIEPSLRSEIEDFPVLGIDCEWVNSEGKASPLSLLQMASPSGFCVLVRLPKLICGGKTLPKTLLDILADGTILKVGVGCSEDASKLLQDYGLVVKGCLDLRYLAMRQRNNLLSNGLSLKSLSETVLNFPLDKSLLLRCSNWDAENLTEDQVIYAARDAQISVALFLHLLGYPFSRNSTLEENDDHIVWRKILEKCQDVVDIPFRSKGLSRSGEEVNGEATESQQKTRNKKSKADGMMPGNQQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLQFEPAGRPESPGDYYLMVKENLCVVCGKKDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDIHLKQQLAREFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPAHRKEELLQGLREFYRTDRVTEEMLQEAASLETRISNENYIPHGLKVVQRHTQGGLRSLMQLESRWRQHFLDSMQPRHLPQQWSVDHNHQKLLRKYGEDLPIKLS", "length": 628 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FEI8-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "Exd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRQNLLALTVTTLLGVAMGGFVLWKGIQRKWSKTSRVMQPQLQPQPQQQQQPQPQQQQQPPQQEQQKQQVPGAREWPPPEDDQLPFGALRTPRASWEERILQAEVVTVSQEAEWNQIQPFLKRELEDFPVLGIDCEWVNLEGKASPLSLLQMASPSGFCALVRLPRLIYGGKTLPRTLLDILADGTILKVGVGCSEDANKLLQDYGLIVRGCLDLRYLAMKQGNSVLCNGLSLKSLAETLLNFPLDKSLLLRCSNWDAENLTEDQVTYAARDAQISVALFLHLLGYPFSRNSYEEENNGQINWQKVLEKCRDMVDIPFRSKGLARLGEEINGEALESQQKPRNRKARTDGMVPGSNQGRDPRKHKRKPLGVGYSARKSPLYDNCFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVVRLQFEPAGRPESPGDYYLMVKENLCVVCGKTDTYIRKNIIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDLERRQVRSGARALLNAESLPAHRKEELLHALREFYNTDIVTEEMLQEAASLETRIYNESYIPHGLKVVQRHTEGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKYGDDLPIKLS", "length": 648 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54YU4-1", "protein_name": "3'-5' exonuclease domain-containing protein", "gene_name": "exdl2A", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKNKNILTNLLNNNKKSFIGTSIIFIAFYWVYNNYIKQIDNKDKDNTENNNENNENNNIVLNKTNDNSNIVKKVKFNNFFKLSNDIKIHVLSTPKECDLILNEFYQSLLLKMNDDKNSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPINTNTIIDGADILNQQQITTESNALLFPNCSEINNDGLDFIIGFDAEWSNFNSIDDSTTTTTTTSKYNHKVALIQLSSKNETFLIQVSQMEKIPTSLEQILTDPRLIKVGVAVSQDAATIFQTFSVVTKGCVDLVPIARLTNYEGNGLASLALNVMNVTLDKSNLIRCSHWENKDLTNDQIHYAAADAWVGREIFEIMYNTYKNSKTDPNEKDLIYTLCRPFINTSFKVKVEKSKNNNTGKPNPNKPIKENMLKKTVPDKRVLYDNCLMYSPDDVLLCSISKKKVEWYVSRQLADIIKEEPLSIKLKFQPHGEGHSGDDYYLAHKENICVVCGSTHKILRHSVVPHCYRQYLPEEIKSHSSHDVLLLCCDCHANMDKRAQIMRMMIAKQYNVPLDSENKVYITDNTLLKITKMALIVKNHFYQQQEQQQEEEKTIINEDGSCSSSTNKISNKKYKSNIPEYKLEEMKVEVANYIGKKEIDLKDLDQLIYLNPKQKNENYIPHEKQVMEKVLALGEKGIFEFIRSWRKNFIETVQPKFLSQHWSINKDILNNYKPKNQKPKQIQLQ", "length": 718 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEG4-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "Exd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRQNLVALTVTTLLGVAMGGFVLWKGIQRRWSKTSRVMQQQPQQPQQPQQPQPQPQPQPQPQPEHPQPQQQVPGGREWPPPEDDQLPFGALRAPRASWEERILQAEVVTVSQEAEWNQIQPFLKRELEDFPVLGIDCEWVNLEGKASPLSLLQMASPSGFCALVRLPRLIYGGRTLPRTLLDILADGAILKVGVGCSEDANKLLQDYGLIVRGCLDLRYLAMKQGNNILCNGLSLKSLAETILNFPLDKSLLLRCSNWDAENLTEDQVTYAARDAQISVALFLHLLGYPFSRDSYEEESTDQINWQKALERCRNMVDIPFRSKGLGRLVEEVNGEALESQLKPRNRKAKTDRMVPGNNQGRDPRKHKRKPLGVGYSARKSPLYDNCFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVVRLQFEPAGRPESPGDYYLMVKENLCVVCGKTDTYIRKNIIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDLERRQVRSGARALLNAESLPAHRKEELLHALREFYNTDIITEEMLHEAASLETRIYNESYIPHGLKVVQRHTEGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKYGDDLPIKLS", "length": 650 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVH0-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "EXD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRQNLVALTVTTLLGVAVGGFVLWKGIQRRRRSKTSPVTQQPQQKVLGSRELPPPEDDQLHSSAPRSSWKERILKAKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKFGEDLPIQLS", "length": 621 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VGN7-1", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "Exd2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRESAVATKRNWAILAAGVGLVYVLVRHRHRLLCPLRRVWSFGSLVPQRRIEVINSVQDPTTQWVLNELKNHCQTFKVLGFDCEWITVGGSRRPVALLQLSSHRGLCALFRLCHMKQIPQDLRELLEDDSVIKVGVAPQEDAMKLSHDYGVGVASTLDLRFLCVMAGHKPEGLGKLSKTHLNYTLDKHWRLACSNWEAKTLEPKQLDYAANDALMAVAIYQKLCRDLQPKHFWQRRQLDDNSMHNKFEPFLDVDFTKGFTLNPSGSGVTRSKGSTQSKSNKWVPKKQPYRQIATRTKDFYDNCLLQAPDGELLCTIDRRKASWYLNQNLGTHISEEPFTVRLNFEPAGRAVGDVGRFYQTIKKNQCVVCGDRDAYIRKNVVPREYRKHFPLVMKSHTSDDVLLLCPTCHQLSNISDLRVRSKLAVQCEAPFKQEDGSVKYHDDPQLKRVQSAGKALLHHGAKIPAAKKAEMEKTLLDYYSDQTDITEDLLRQAASVEYRVENSDYCQHGERVVQQYRDHFGGLVELERLWRQHFLHTMQPRFLPELWNVNHNADRLEVRASEGRIDKADLMVAGLDAKIKET", "length": 583 }, "evidence": [ { "id": "A0A8V0Z6W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z6W7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "single-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6X2-1", "uniprot_ac": "A0A8V0Z6X2", "uniprot_id": "A0A8V0Z6X2_CHICK", "mass": { "chemical_mass": 47290.0, "monoisotopic_mass": 47290.0 }, "refseq": {}, "gene_names": [ { "name": "GXYLT2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ] } ], "protein_names": [ { "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.42", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2/entry#names_and_taxonomy" } ] } ], "function": [ { 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] }, { "id": "PTHR46012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46012:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46012:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "56064", "url": "https://www.rhea-db.org/rhea/56064", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCRTPTARLFPSTSGCSSPYPLSPLPPAHHLSIHTRPRCTEPYTSGDLCEVGNLRKPGEQKRSKEPSSLQCMHLAVVACGDRLEETLIMLKSAVLFSNRRLCFHIFSEDALKPEFNKKLQEWPSSYTKKFEYNIYPITFSVGNAQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPIDDIWHILKEFNSTQLAAMAPEHEIPKIGWYSRFARHPYYGTTGVNSGVMLMNLTRIRNTQFRNSMIPSGLTWEEMLYPLYQKYKNYITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCKGAEEEGVSILHGNRGVYHDDKQPTFKALYEVIRDFPFEDNLFQSLYYPLQSKFLDTVHTLCGRIPQVFLKQIEKTMKKVYENRVIVYLGANHRY", "length": 406, "header": "tr|A0A8V0Z6X2-1|A0A8V0Z6X2_CHICK Isoform 1 of UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase OS=Gallus gallus OX=9031 GN=GXYLT2 PE=3 SV=1 CANONICAL=A0A8V0Z6X2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2/entry#A0A8V0Z6X2-1", "sequence": { "sequence": "MGCRTPTARLFPSTSGCSSPYPLSPLPPAHHLSIHTRPRCTEPYTSGDLCEVGNLRKPGEQKRSKEPSSLQCMHLAVVACGDRLEETLIMLKSAVLFSNRRLCFHIFSEDALKPEFNKKLQEWPSSYTKKFEYNIYPITFSVGNAQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPIDDIWHILKEFNSTQLAAMAPEHEIPKIGWYSRFARHPYYGTTGVNSGVMLMNLTRIRNTQFRNSMIPSGLTWEEMLYPLYQKYKNYITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCKGAEEEGVSILHGNRGVYHDDKQPTFKALYEVIRDFPFEDNLFQSLYYPLQSKFLDTVHTLCGRIPQVFLKQIEKTMKKVYENRVIVYLGANHRY", "length": 406, "header": "tr|A0A8V0Z6X2-1|A0A8V0Z6X2_CHICK Isoform 1 of UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase OS=Gallus gallus OX=9031 GN=GXYLT2 PE=3 SV=1 CANONICAL=A0A8V0Z6X2-1" }, "locus": { "chromosome": "12", "start_pos": 16701938, "end_pos": 16684022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049017.1", "url": "https://www.ensembl.org/id/ENSGALT00010049017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028978.1", "url": "https://www.ensembl.org/id/ENSGALP00010028978.1" } ] } } ], "glycosylation": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "UDP-xylosyltransferase activity", "id": "GO:0035252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ], "pmid": "" }, { "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity", "id": "GO:0140563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140563", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56064", "name": "", "equation": "3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZKI6-1", "A0A8V0XEP1-1", "A0A8V0Z6X2-1" ], "evidence": [ { "id": "56064", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56064" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XEP1", "gene_name": "GXYLT1", "activity": [ { "ec_number": "2.4.2.42", "activity": "3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0XEP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEP1" } ] }, { "ec_number": "2.4.2.42", "activity": "", "evidence": [ { "id": "A0A8V0XEP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEP1" } ] } ] }, { "uniprot_ac": "A0A8V0Z6X2", "gene_name": "GXYLT2", "activity": [ { "ec_number": "2.4.2.42", "activity": "3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0Z6X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ] }, { "ec_number": "2.4.2.42", "activity": "", "evidence": [ { "id": "A0A8V0Z6X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X2" } ] } ] }, { "uniprot_ac": "Q5ZKI6", "gene_name": "GXYLT1", "activity": [ { "ec_number": "2.4.2.42", "activity": "3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "Q5ZKI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI6" } ] }, { "ec_number": "2.4.2.42", "activity": "", "evidence": [ { "id": "Q5ZKI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.2.42", "ec_name": "3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "2.4.2.42", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.42" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 237, "end_pos": 239 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6X7-1", "uniprot_ac": "A0A8V0Z6X7", "uniprot_id": "A0A8V0Z6X7_CHICK", "mass": { "chemical_mass": 8414.0, "monoisotopic_mass": 8414.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6X7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR015468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10441:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGSPTLLLLLSLGLCCTDAQGQTDAVADRFLNRNMKHPQEGQQLELECPPYDRDKPIFWIRLDKFGNIHFLVS", "length": 74, "header": "tr|A0A8V0Z6X7-1|A0A8V0Z6X7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6X7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X7/entry#A0A8V0Z6X7-1", "sequence": { "sequence": "MPGSPTLLLLLSLGLCCTDAQGQTDAVADRFLNRNMKHPQEGQQLELECPPYDRDKPIFWIRLDKFGNIHFLVS", "length": 74, "header": "tr|A0A8V0Z6X7-1|A0A8V0Z6X7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z6X7-1" }, "locus": { "chromosome": "4", "start_pos": 85354470, "end_pos": 85353788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041373.1", "url": "https://www.ensembl.org/id/ENSGALT00010041373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024237.1", "url": "https://www.ensembl.org/id/ENSGALP00010024237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6X8-1", "uniprot_ac": "A0A8V0Z6X8", "uniprot_id": "A0A8V0Z6X8_CHICK", "mass": { "chemical_mass": 98215.0, "monoisotopic_mass": 98215.0 }, "refseq": {}, "gene_names": [ { "name": "PACS3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" } ] } ], "protein_names": [ { "name": "Phosphofurin acidic cluster sorting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PACS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z6X8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6X8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6X8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6X8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Y2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13280:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13280:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVAGPGPVPVPMNLFATWEIDRSAPSCVPRLCSLRLKKLTVLKELDKELSSVLIAVKIQGSKRVLRSNEYVLPPGGLMETELELTFSLQYPHFLKRDGNKLQIMLQRRKRYKNRTILGYKTLAVGIINMAEVMQHPTDGGQLLSLHSNMKDVNIRVAEISIYSLSSQPIDHEDGSVPSGPKIKASDRSPDIDNYSEEEDDSFSSEQEASDDAVQGQDLFDEEDDLRKTKKARRKMIRTTSMTRQPNFKQKFVALLKRFKVTEEVLDSDPVDQTQEVEEDLGLLYDSLEECNNSDSGPEIEDNESVHSTPKPTLRRFFEGVSHSGSQTEIGSLHSQKGQDQESGSPGEAEKRKPGAPRAQEEPGAEVPVVELAAEEPCPRLAPPEAATRESSMDRLAQLGPGTKSELPSAVSPSKAESKQLWRPRSTSVKDRQSSKGQSGRTSSLDSESSPDSWHSTQVPRKSVYDQLNQILVSDEQLPESIVLVNVAEWQGQYVSEQLQAHKQLVVSTCSVADIQAAFNTTVSRIQRYCNCNSHMPPPVKVVVAGDQSYLSVVLRFFVEQLASKTPDWLNYLRFLLVPLGSHPLAKYLASVDNKYSTLFLDTAWRELFSRAEPPTADTVDIAGRVAQFIAGASLSHQLPISEAMLTYKQKRKRSLYFDFYISPDEDSCQKFIPFVGVVKVGLVEQSFSASVDSDDATACTPSLLSSVPAAGSASPYGKETVSTPPPSPSVSSGLSGAGSLSPGVEVMGLQVDYWTTQGLDRKKEGEKRETGIKNTLKSNFRSLQVSRIPGVGELVPPSTMAMTVVTKEKNKKVMFLSKKPKEKDLEPKSQVIEGITRLICTAKHQNTMLRVSIDGVEWNDVKFFQLAAQWPTHVKYLPVGIFGYSKSV", "length": 889, "header": "tr|A0A8V0Z6X8-1|A0A8V0Z6X8_CHICK Isoform 1 of Phosphofurin acidic cluster sorting protein 1 OS=Gallus gallus OX=9031 GN=PACS3 PE=1 SV=1 CANONICAL=A0A8V0Z6X8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8/entry#A0A8V0Z6X8-1", "sequence": { "sequence": "MAVAGPGPVPVPMNLFATWEIDRSAPSCVPRLCSLRLKKLTVLKELDKELSSVLIAVKIQGSKRVLRSNEYVLPPGGLMETELELTFSLQYPHFLKRDGNKLQIMLQRRKRYKNRTILGYKTLAVGIINMAEVMQHPTDGGQLLSLHSNMKDVNIRVAEISIYSLSSQPIDHEDGSVPSGPKIKASDRSPDIDNYSEEEDDSFSSEQEASDDAVQGQDLFDEEDDLRKTKKARRKMIRTTSMTRQPNFKQKFVALLKRFKVTEEVLDSDPVDQTQEVEEDLGLLYDSLEECNNSDSGPEIEDNESVHSTPKPTLRRFFEGVSHSGSQTEIGSLHSQKGQDQESGSPGEAEKRKPGAPRAQEEPGAEVPVVELAAEEPCPRLAPPEAATRESSMDRLAQLGPGTKSELPSAVSPSKAESKQLWRPRSTSVKDRQSSKGQSGRTSSLDSESSPDSWHSTQVPRKSVYDQLNQILVSDEQLPESIVLVNVAEWQGQYVSEQLQAHKQLVVSTCSVADIQAAFNTTVSRIQRYCNCNSHMPPPVKVVVAGDQSYLSVVLRFFVEQLASKTPDWLNYLRFLLVPLGSHPLAKYLASVDNKYSTLFLDTAWRELFSRAEPPTADTVDIAGRVAQFIAGASLSHQLPISEAMLTYKQKRKRSLYFDFYISPDEDSCQKFIPFVGVVKVGLVEQSFSASVDSDDATACTPSLLSSVPAAGSASPYGKETVSTPPPSPSVSSGLSGAGSLSPGVEVMGLQVDYWTTQGLDRKKEGEKRETGIKNTLKSNFRSLQVSRIPGVGELVPPSTMAMTVVTKEKNKKVMFLSKKPKEKDLEPKSQVIEGITRLICTAKHQNTMLRVSIDGVEWNDVKFFQLAAQWPTHVKYLPVGIFGYSKSV", "length": 889, "header": "tr|A0A8V0Z6X8-1|A0A8V0Z6X8_CHICK Isoform 1 of Phosphofurin acidic cluster sorting protein 1 OS=Gallus gallus OX=9031 GN=PACS3 PE=1 SV=1 CANONICAL=A0A8V0Z6X8-1" }, "locus": { "chromosome": "3", "start_pos": 4531191, "end_pos": 4489158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044781.1", "url": "https://www.ensembl.org/id/ENSGALT00010044781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026703.1", "url": "https://www.ensembl.org/id/ENSGALP00010026703.1" } ] } }, { "isoform_ac": "A0A8V0Z6Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8/entry#A0A8V0Z6Y2-1", "sequence": { "sequence": "MAVAGPGPVPVPMNLFATWEIDRSAPSCVPRLCSLRLKKLTVLKELDKELSSVLIAVKIQGSKRVLRSNEYVLPPGGLMETELELTFSLQYPHFLKRDGNKLQIMLQRRKRYKNRTILGYKTLAVGIINMAEVMQHPTDGGQLLSLHSNMKDVNIRVAEISIYSLSSQPIDHEDGSVPSGPKIKASDRSPDIDNYSEEEDDSFSSEQEASDDAVQGQDLFDEEDDLRKTKKARRKMIRTTSMTRQPNFKQKFVALLKRFKVTEEVLDSDPVDQTQEVEEDLGLLYDSLEECNNSDSGPEIEDNESVHSTPKPTLRRFFEGVSHSGSQTEIGSLHSQKGQDQESGSPGEAEKRKPGAPRAQEEPGAEVPVVELAAEEPCPRLAPPEAATRESSMDRLAQLGPGTKSELPSAVSPSKAESKQLWRPRSTSVKDRQSSKGQSGRTSSLDSESSPDSWHSTQVPRKSVYDQLNQILVSDEQLPESIVLVNVAEWQGQYVSEQLQAHKQLVVSTCSVADIQAAFNTTVSRIQRYCNCNSHMPPPVKVVVAGDQSYLSVVLRFFVEQLASKTPDWLNYLRFLLVPLGSHPLAKYLASVDNKYSTLFLDTAWRELFSRAEPPTADTVDIAGRVAQFIAGASLSHQLPISEAMLTYKQKSPDEDSCQKFIPFVGVVKVGLVEQSFSASVDSDDATACTPSLLSSVPAAGSASPYGKETVSTPPPSPSVSSGLSGAGSLSPGVEVMGLQVDYWTTQGLDRKKEGEKRETGIKNTLKSNFRSLQVSRIPGVGELVPPSTMAMTVVTKEKNKKVMFLSKKPKEKDLEPKSQVIEGITRLICTAKHQNTMLRVSIDGVEWNDVKFFQLAAQWPTHVKYLPVGIFGYSKSV", "length": 878, "header": "tr|A0A8V0Z6Y2-1|A0A8V0Z6Y2_CHICK Computationally mapped isoform of Phosphofurin acidic cluster sorting protein 1 OS=Gallus gallus OX=9031 GN=PACS3 PE=1 SV=1 CANONICAL=A0A8V0Z6X8-1" }, "locus": { "chromosome": "3", "start_pos": 4531191, "end_pos": 4489158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044786.1", "url": "https://www.ensembl.org/id/ENSGALT00010044786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026708.1", "url": "https://www.ensembl.org/id/ENSGALP00010026708.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" }, { "id": "PF10254", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10254" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphofurin acidic cluster sorting protein 1/2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 464, "end_pos": 886, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6X8" }, { "id": "PF25332", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphofurin acidic cluster sorting protein 1/2 N-terminal C2", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 171, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z6Z2-1", "uniprot_ac": "A0A8V0Z6Z2", "uniprot_id": "A0A8V0Z6Z2_CHICK", "mass": { "chemical_mass": 90060.0, "monoisotopic_mass": 90060.0 }, "refseq": { "ac": "XP_425260", "name": "leucine-rich repeat neuronal protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425260" }, "gene_names": [ { "name": "LRRN4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z6Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2" } ] }, { "name": "LRRN4", "type": "synonym", "evidence": [ { "id": "XP_425260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425260" } ] } ], "protein_names": [ { "name": "Leucine rich repeat neuronal 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z6Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat neuronal protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_425260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425260" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425260.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425260" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2", "locus": { "chromosome": "3", "start_pos": 15025529, "end_pos": 15015570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018516", "url": "https://www.ensembl.org/id/ENSGALG00010018516" } ] } } ], "crossref": [ { "id": "A0A8V0Z6Z2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z6Z2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427686", "url": "https://www.ncbi.nlm.nih.gov/gene/427686", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427686", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427686", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTQQGPW", "url": "https://omabrowser.org/oma/group/LTQQGPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Z2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRQRRGARRRGSRADLATNCKPSSRKMFSLLFILCLLERNTASGPVSRAEPAASRDFTTVFQLAQGDPWENVNLTSMSCEDRKNRTWITLQLTNSSLTAFPICLPEVLQTLDLSNNLLEEVNGTEIANLPRLRVLSLRQNLLQAVRWGSETFSSLHFLDLSFNKLSSVPPCHTSSMPNLRWLSLAGNPLTEIQPLAFSCYPQLQFLNLSTTLLGHEGSRGIQESAFAISLSPGDALHSPENTISVLDLSGTFLERIQVEWTRDLPNLRLLHLTKMPQLRSLDTDFRSMPHLRELNCRDSHSLGFVRTEMFESTPNLSHLSFQNCNLSSFNSWNTNSSDTIIINLHGNPLQCDCRLSWLLSTPKIVLQKASDTFCTTSQENWDRPSVSFSLQELYNKCQTEKDISLLDSNTPSSQGDAFSLASYYTTTAAVTTDSALLIKDTYIPLNEEASVMSTTAANPAELMLTKANGSSPKDEAVSESMSHPPLLTSLTTSPGFLRELYSQTTDYGSVSQTETQQLQGELRKTHMAFPQERLFSQPASERSTPATGKPDAVPHYIHSFAVERTPQTNLRQPNSTKSSTQSASAPTRPRIHYVDDYEYSEETTEPPVQQTYTSCDYNPCRHLQKPCSELQRASPCLCPGMSTENEIPDPPRLREVSEVTDSSAQIHWCAPNSVVRTYQLLLRDQGSEEGQLVLEDIYSTARQYTLYNLSPYTTYHVCVTASNSAGLSHAVSQGTAGNSCARFRTKPSYKSVFAALSAASGLFLISTIILSICLCKARKKPHSEQYGTHLVSYKNPAFDYPLKLQTAD", "length": 809, "header": "tr|A0A8V0Z6Z2-1|A0A8V0Z6Z2_CHICK Isoform 1 of Leucine rich repeat neuronal 4 OS=Gallus gallus OX=9031 GN=LRRN4 PE=1 SV=1 CANONICAL=A0A8V0Z6Z2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2/entry#A0A8V0Z6Z2-1", "sequence": { "sequence": "MLRQRRGARRRGSRADLATNCKPSSRKMFSLLFILCLLERNTASGPVSRAEPAASRDFTTVFQLAQGDPWENVNLTSMSCEDRKNRTWITLQLTNSSLTAFPICLPEVLQTLDLSNNLLEEVNGTEIANLPRLRVLSLRQNLLQAVRWGSETFSSLHFLDLSFNKLSSVPPCHTSSMPNLRWLSLAGNPLTEIQPLAFSCYPQLQFLNLSTTLLGHEGSRGIQESAFAISLSPGDALHSPENTISVLDLSGTFLERIQVEWTRDLPNLRLLHLTKMPQLRSLDTDFRSMPHLRELNCRDSHSLGFVRTEMFESTPNLSHLSFQNCNLSSFNSWNTNSSDTIIINLHGNPLQCDCRLSWLLSTPKIVLQKASDTFCTTSQENWDRPSVSFSLQELYNKCQTEKDISLLDSNTPSSQGDAFSLASYYTTTAAVTTDSALLIKDTYIPLNEEASVMSTTAANPAELMLTKANGSSPKDEAVSESMSHPPLLTSLTTSPGFLRELYSQTTDYGSVSQTETQQLQGELRKTHMAFPQERLFSQPASERSTPATGKPDAVPHYIHSFAVERTPQTNLRQPNSTKSSTQSASAPTRPRIHYVDDYEYSEETTEPPVQQTYTSCDYNPCRHLQKPCSELQRASPCLCPGMSTENEIPDPPRLREVSEVTDSSAQIHWCAPNSVVRTYQLLLRDQGSEEGQLVLEDIYSTARQYTLYNLSPYTTYHVCVTASNSAGLSHAVSQGTAGNSCARFRTKPSYKSVFAALSAASGLFLISTIILSICLCKARKKPHSEQYGTHLVSYKNPAFDYPLKLQTAD", "length": 809, "header": "tr|A0A8V0Z6Z2-1|A0A8V0Z6Z2_CHICK Isoform 1 of Leucine rich repeat neuronal 4 OS=Gallus gallus OX=9031 GN=LRRN4 PE=1 SV=1 CANONICAL=A0A8V0Z6Z2-1" }, "locus": { "chromosome": "3", "start_pos": 15024283, "end_pos": 15016449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044796.1", "url": "https://www.ensembl.org/id/ENSGALT00010044796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026718.1", "url": "https://www.ensembl.org/id/ENSGALP00010026718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427686", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427686", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LTX4-1", "protein_name": "Leucine rich repeat neuronal 4", "gene_name": "Lrrn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWTLMLQLLQLLLQLQMVQSHSLEGLSQHQIPLFRLTQLGVWDSHDRRPNDSSCEGLPAAGATTLNLANRSLERLPSCLPRTLRILDGSHNLLHALSEPVLRRLPELSVLTLHHNRISVLHWDGSTPTGLHELDLSHNLLAELPPCSGLSRSSLSLLSLAGNPLQALQPRTFACFPELQFLNLSCSKLGHIAQEAFAGVDGGPLEALELLDLSGTNLERVESEWIRNLPKLKSLYLRKMPRLKTLEGDIFKMTPNLRLLDCQESPALTSVHTEIFQDTPNLQVLQLQNCNLSSFGPWTVNSSQVLLVSLFGNPLICSCELAWLLLDASKTVLHRAADTTCEPALGSKGPFSGPLPLSHLSNVCRSDQSTTLLASNPPHDHHSVSAPWTQEPSIGQSRALSAQPEGSQQNITKVPSLTMAPPTQGSRTYRDTSEETAQSTTNSEIVYSPSRALPGTASSGAEQTDTYILEPSISSASTPLVSKYLEPSPTSPNPRSISQINQRTQANPKAFHTDPPQDEIPVLLLDDDSEEETTQDQVAAPRQDVSCDYHPCRHLQTPCAELQKRLRCRCPGLSGQDTIPDPPKLQGVSEMTDTSVLIHWCAPNSVVLWYQIHYLAEGGSGNRSVTDIYATARQHPLYKLSPGTTYHVCVLAANRAGLSQPQTSGWGRSCATFTTKPSSVVIFWGLCTASGLLLVSTLVLSVCLWRQRWKPHRQFHDTHLVAFKNPARSEEVTQW", "length": 735 }, "evidence": [ { "id": "A0A8V0Z6Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6Z2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59383-1", "protein_name": "Leucine-rich repeat neuronal protein 4", "gene_name": "Lrrn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRWTLMLQLLQLLLQLLMAQSQSLERISQDRIPLFRLTQQGDWDSLDRHPTDSLCVGLPAAGVTTLNLANRSLESLPSCLPRTLRSLDGSHNLLRALSEPVLGRLPELRVLTLHHNRISVLHWGRDTLAELRELDLSHNLLTELPPCAGPSGSSLRSLALAGNPLRALLPRTFACFPALRLLNLSCSELGHIAQEAFAGVDGGPLAALELLDLSGTSLERVESGWIRNLPKLKSLFLRKMPRLKTLEGDIFKMTPNLRQLDCGDSPALTSVHTEIFQDTPNLQVLQFQNCNLSSFGPWNSSQVLSVSLFGNPLICSCELAWLLVDVNKTVLHRAADTMCEPALGSTGPFSGPLSLSHLSNVCRSDQSTTLLPSNPGRFDHSVFAPRIQGPSIEQSTALSAQPGGSQQNITKVPSLTMTSPTQGSWMYKDASEETAQSTNSELVYSPSRALPGAASSGAEQTATHILEPNISSASTPLVSKYLEPLPTSPNPRSLPQTKQRTQATPRALHTDPPQDEIPVLLLDDDSEEEETRDQVAAPPQDVSCEYHPCKHLQTPCAELQRRFRCRCPGLSGEDTTPDPPTLQGVSEVTDTSVLVHWCAPNSVVLWYQIHYVAEGRSGNQSVVDIYATARQHPLYKLTPGTTYHVCVLAANRAGLSQSQTSGWRRSCATFTTKPSSVVIFWGLCTASGLLLVSTLVLSVCLWRQRWKPHRQFYDTHLVAFKNPARAEEVTQWE", "length": 733 }, "evidence": [ { "id": "A0A8V0Z6Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6Z2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUT4-1", "protein_name": "Leucine-rich repeat neuronal protein 4", "gene_name": "LRRN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQTLPLLLLTVLRPSWADPPQEKVPLFRVTQQGPWGSSGSNATDSPCEGLPAADATALTLANRNLERLPGCLPRTLRSLDASHNLLRALSTSELGHLEQLQVLTLRHNRIAALRWGPGGPAGLHTLDLSYNQLAALPPCTGPALSSLRALALAGNPLRALQPRAFACFPALQLLNLSCTALGRGAQGGIAEAAFAGEDGAPLVTLEVLDLSGTFLERVESGWIRDLPKLTSLYLRKMPRLTTLEGDIFKMTPNLQQLDCQDSPALASVATHIFQDTPHLQVLLFQNCNLSSFPPWTLDSSQVLSINLFGNPLTCSCDLSWLLTDAKRTVLSRAADTMCAPAAGSSGPFSASLSLSQLPGVCQSDQSTTLGASHPPCFNRSTYAQGTTVAPSAAPATRPAGDQQSVSKAPNVGSRTIAAWPHSDAREGTAPSTTNSVAGHSNSSVFPRAASTTRTQHRGEHAPELVLEPDISAASTPLASKLLGPFPTSWDRSISSPQPGQRTHATPQAPNPSLSEGEIPVLLLDDYSEEEEGRKEEVGTPHQDVPCDYHPCKHLQTPCAELQRRWRCRCPGLSGEDTIPDPPRLQGVTETTDTSALVHWCAPNSVVHGYQIRYSAEGWAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAANRAGLSQPRSSGWRSPCAAFTTKPSFALLLSGLCAASGLLLASTVVLSACLCRRGQTLGLQRCDTHLVAYKNPAFDDYPLGLQTVS", "length": 740 }, "evidence": [ { "id": "A0A8V0Z6Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z6Z2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z6Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 651, "end_pos": 749, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 85, "end_pos": 87 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"Protein" ] } ], "sequence": { "sequence": "MMSYLQPPGRDPERFDGLSLIYWTLMGPYGMDRTVHCFEFYDCANGLGIKVIGGIKELTGEEYGVYVKRILPGGVAYADGRLQPGDQILEVNGDSLIGVTSERAVDILRTASATSHMRLLIARDDDARREFSELLEKFGSQSNTGSARSSPVLHGGSRYLESTSSGSSSRSQSPLLLSPASSHSPFIGNPAHAPHAHYSIESGIQSISIAKSSGLGLTVSGGANRPDGPMVYIQELTPDGDCYKDGRLRPGDQLIAINRDSLVGSTLEEARKIIAKAKFRHEGNTEVAFIPGRGRLHPGLSAHNNIPSPPPPKAVGNGLSSCRLKVHVRSPESRHENHFPVPSLSPDICPPELTVSAPCSAPSLRAATGSKPKVALDPHIRLKDGKLELVLQYLGLEVTEEKKRQLRQSLTTDSQGTVAYGDLLQALRDVMQDELDEAGLDSSSVLFTQHEVANLLDTSAFHSPTLDSLSCNGSEEMEQLQLEMTDLRQEVRRLKSLLKEVENSKKSMEDELQRLNQKALGFLSENRTLHSKLQMAEVVQRQAHSAEQDYEEVIHLLEAEIAELKMQLAGKKAKHVAEIEEDILELKRQLSVADGQLRKSEVSRKRLEICNRKLLLFVQNVHKVLSTPGHLADEKRVNSETEEDKTDAVSDTSLPSSDLVDLLLSEAKELLAPMLSNKDASPCDRDQCLPAEGLPNYKDHLHQKTTWPPPPSQNKGDQPQSPSPTKELPAKPT", "length": 733, "header": "tr|A0A8V0Z702-1|A0A8V0Z702_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857632 PE=4 SV=1 CANONICAL=A0A8V0Z702-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z702-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z702/entry#A0A8V0Z702-1", "sequence": { "sequence": "MMSYLQPPGRDPERFDGLSLIYWTLMGPYGMDRTVHCFEFYDCANGLGIKVIGGIKELTGEEYGVYVKRILPGGVAYADGRLQPGDQILEVNGDSLIGVTSERAVDILRTASATSHMRLLIARDDDARREFSELLEKFGSQSNTGSARSSPVLHGGSRYLESTSSGSSSRSQSPLLLSPASSHSPFIGNPAHAPHAHYSIESGIQSISIAKSSGLGLTVSGGANRPDGPMVYIQELTPDGDCYKDGRLRPGDQLIAINRDSLVGSTLEEARKIIAKAKFRHEGNTEVAFIPGRGRLHPGLSAHNNIPSPPPPKAVGNGLSSCRLKVHVRSPESRHENHFPVPSLSPDICPPELTVSAPCSAPSLRAATGSKPKVALDPHIRLKDGKLELVLQYLGLEVTEEKKRQLRQSLTTDSQGTVAYGDLLQALRDVMQDELDEAGLDSSSVLFTQHEVANLLDTSAFHSPTLDSLSCNGSEEMEQLQLEMTDLRQEVRRLKSLLKEVENSKKSMEDELQRLNQKALGFLSENRTLHSKLQMAEVVQRQAHSAEQDYEEVIHLLEAEIAELKMQLAGKKAKHVAEIEEDILELKRQLSVADGQLRKSEVSRKRLEICNRKLLLFVQNVHKVLSTPGHLADEKRVNSETEEDKTDAVSDTSLPSSDLVDLLLSEAKELLAPMLSNKDASPCDRDQCLPAEGLPNYKDHLHQKTTWPPPPSQNKGDQPQSPSPTKELPAKPT", "length": 733, "header": "tr|A0A8V0Z702-1|A0A8V0Z702_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857632 PE=4 SV=1 CANONICAL=A0A8V0Z702-1" }, "locus": { "chromosome": "14", "start_pos": 13331694, "end_pos": 13295880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045064.1", "url": "https://www.ensembl.org/id/ENSGALT00010045064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026925.1", "url": "https://www.ensembl.org/id/ENSGALP00010026925.1" } ] } }, { "isoform_ac": "A0A8V0Z7J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z702/entry#A0A8V0Z7J1-1", "sequence": { "sequence": "MPAVSVLYKGAIIISRTLMGPYGMDRTVHCFEFYDCANGLGIKVIGGIKELTGEEYGVYVKRILPGGVAYADGRLQPGDQILEVNGDSLIGVTSERAVDILRTASATSHMRLLIARDDDARREFSELLEKFGSQSNTGSARSSPVLHGGSRYLESTSSGSSSRSQSPLLLSPASSHSPFIGNPAHAPHAHYSIESGIQSISIAKSSGLGLTVSGGANRPDGPMVYIQELTPDGDCYKDGRLRPGDQLIAINRDSLVGSTLEEARKIIAKAKFRHEGNTEVAFIPGRGRLHPGLSAHNNIPSPPPPKAVGNGLSSCRLKVHVRSPESRHENHFPVPSLSPDICPPELTVSAPCSAPSLRAATGSKPKVALDPHIRLKDGKLELVLQYLGLEVTEEKKRQLRQSLTTDSQGTVAYGDLLQALRDVMQDELDEAGLDSSSVLFTQHEVANLLDTSAFHSPTLDSLSCNGSEEMEQLQLEMTDLRQEVRRLKSLLKEVENSKKSMEDELQRLNQKALGFLSENRTLHSKLQMAEVVQRQAHSAEQDYEEVIHLLEAEIAELKMQLAGKKAKHVAEIEEDILELKRQLSVADGQLRKSEVSRKRLEICNRKLLLFVQNVHKVLSTPGHLADEKRVNSETEEDKTDAVSDTSLPSSDLVDLLLSEAKELLAPMLSNKDASPCDRDQCLPAEGLPNYKDHLHQKTTWPPPPSQNKGDQPQSPSPTKELPAKPT", "length": 726, "header": "tr|A0A8V0Z7J1-1|A0A8V0Z7J1_CHICK Computationally mapped isoform of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857632 PE=4 SV=1 CANONICAL=A0A8V0Z702-1" }, "locus": { "chromosome": "14", "start_pos": 13331694, "end_pos": 13301973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045060.1", "url": "https://www.ensembl.org/id/ENSGALT00010045060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026922.1", "url": "https://www.ensembl.org/id/ENSGALP00010026922.1" } ] } }, { "isoform_ac": "A0A8V0Z8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z702/entry#A0A8V0Z8I6-1", "sequence": { "sequence": "MTLMGPYGMDRTVHCFEFYDCANGLGIKVIGGIKELTGEEYGVYVKRILPGGVAYADGRLQPGDQILEVNGDSLIGVTSERAVDILRTASATSHMRLLIARDDDARREFSELLEKFGSQSNTGSARSSPVLHGGSRYLESTSSGSSSRSQSPLLLSPASSHSPFIGNPAHAPHAHYSIESGIQSISIAKSSGLGLTVSGGANRPDGPMVYIQELTPDGDCYKDGRLRPGDQLIAINRDSLVGSTLEEARKIIAKAKFRHEGNTEVAFIPGRGRLHPGLSAHNNIPSPPPPKAVGNGLSSCRLKVHVRSPESRHENHFPVPSLSPDICPPELTVSAPCSAPSLRAATGSKPKVALDPHIRLKDGKLELVLQYLGLEVTEEKKRQLRQSLTTDSQGTVAYGDLLQALRDVMQDELDEAGLDSSSVLFTQHEVANLLDTSAFHSPTLDSLSCNGSEEMEQLQLEMTDLRQEVRRLKSLLKEVENSKKSMEDELQRLNQKALGFLSENRTLHSKLQMAEVVQRQAHSAEQDYEEVIHLLEAEIAELKMQLAGKKAKHVAEIEEDILELKRQLSVADGQLRKSEVSRKRLEICNRKLLLFVQNVHKVLSTPGHLADEKRVNSETEEDKTDAVSDTSLPSSDLVDLLLSEAKELLAPMLSNKDASPCDRDQCLPAEGLPNYKDHLHQKTTWPPPPSQNKGDQPQSPSPTKELPAKPT", "length": 711, "header": "tr|A0A8V0Z8I6-1|A0A8V0Z8I6_CHICK Computationally mapped isoform of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857632 PE=4 SV=1 CANONICAL=A0A8V0Z702-1" }, "locus": { "chromosome": "14", "start_pos": 13331694, "end_pos": 13294550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045067.1", "url": "https://www.ensembl.org/id/ENSGALT00010045067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026926.1", "url": "https://www.ensembl.org/id/ENSGALP00010026926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z702" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 123, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 472, "end_pos": 474 }, { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z708-1", "uniprot_ac": "A0A8V0Z708", "uniprot_id": "A0A8V0Z708_CHICK", "mass": { "chemical_mass": 10251.0, "monoisotopic_mass": 10251.0 }, "refseq": { "ac": "XP_040561582", "name": "protein NCBP2AS2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561582" }, "gene_names": [ { "name": "NCBP2AS2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708" } ] }, { "name": "NCBP2AS2", "type": "synonym", "evidence": [ { "id": "XP_040561582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561582" } ] } ], "protein_names": [ { "name": "NCBP2 antisense 2 (head to head)", "type": "synonym", "evidence": [ { "id": "A0A8V0Z708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708/entry#names_and_taxonomy" } ] }, { "name": "protein NCBP2AS2", "type": "synonym", "evidence": [ { "id": "XP_040561582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561582" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561582" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z708", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCBP2AS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z708", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z708", "database": "AlphaFoldDB", "categories": [] }, { "id": "121111542", "url": "https://www.ncbi.nlm.nih.gov/gene/121111542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DRMVHEN", "url": "https://omabrowser.org/oma/group/DRMVHEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z708", "url": "https://www.orthodb.org/?gene=A0A8V0Z708", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR41161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41161:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41161:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040561582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561582", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z708", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z708-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLRRVLLALLSNPHLIEKLAESRPIRAAARLTASAITRGQLGARQAARDLRPGLTRLRDAFLDRLKDGGRPRGWPESPGRGPGSGRGPGRSGRP", "length": 95, "header": "tr|A0A8V0Z708-1|A0A8V0Z708_CHICK Isoform 1 of NCBP2 antisense 2 (head to head) OS=Gallus gallus OX=9031 GN=NCBP2AS2 PE=4 SV=1 CANONICAL=A0A8V0Z708-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z708-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z708/entry#A0A8V0Z708-1", "sequence": { "sequence": "MVLRRVLLALLSNPHLIEKLAESRPIRAAARLTASAITRGQLGARQAARDLRPGLTRLRDAFLDRLKDGGRPRGWPESPGRGPGSGRGPGRSGRP", "length": 95, "header": "tr|A0A8V0Z708-1|A0A8V0Z708_CHICK Isoform 1 of NCBP2 antisense 2 (head to head) OS=Gallus gallus OX=9031 GN=NCBP2AS2 PE=4 SV=1 CANONICAL=A0A8V0Z708-1" }, "locus": { "chromosome": "9", "start_pos": 12142478, "end_pos": 12142194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045072.1", "url": "https://www.ensembl.org/id/ENSGALT00010045072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026930.1", "url": "https://www.ensembl.org/id/ENSGALP00010026930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0Z718", "uniprot_id": "A0A8V0Z718_CHICK", "mass": { "chemical_mass": 25642.0, "monoisotopic_mass": 25642.0 }, "refseq": { "ac": "XP_003641327", "name": "calcium-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641327" }, "gene_names": [ { "name": "CABP4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z718" } ] }, { "name": "CABP4", "type": "synonym", "evidence": [ { "id": "XP_003641327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641327" } ] } ], "protein_names": [ { "name": "Calcium binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z718/entry#names_and_taxonomy" } ] }, { "name": "calcium-binding protein 2", "type": "synonym", "evidence": [ { "id": "XP_003641327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641327" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641327.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641327" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z718", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z718" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CABP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z718", "locus": { "chromosome": "5", "start_pos": 187718, "end_pos": 184173, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020334", "url": "https://www.ensembl.org/id/ENSGALG00010020334" } ] } } ], "crossref": [ { "id": "A0A8V0Z718", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z718", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857896", "url": "https://www.ncbi.nlm.nih.gov/gene/100857896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857896", "database": "KEGG Pathway", "categories": [ 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} ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QL39-1", "protein_name": "Calcium-binding protein 4", "gene_name": "CABP4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATEQRGEQHGAPQQPPGGVEASGRGAEGLPLTRRRSSKKKGLRGSRKDSGSSGEQPPPQGPEAPESSKNPSRTREGQEGPGPVAPALASRRQSHRHRPASQHDAAQRTYGPLLNRIFGKDRELGPEELDELRAAFEEFDTDHDGHIGYRELGECMRTLGYMPTEMELIEVSQHVKMRMGGRVDFEEFVEMMGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELRQAAPALLGEPLAGSELDEMLREVDLNGDGTVDFDGEFPILPATPPHSSGSQAEPSASGAAGGGVSLTWTCPSPAPSLPQSL", "length": 311 }, "evidence": [ { "id": "A0A8V0Z718", "url": "https://omabrowser.org/oma/group/A0A8V0Z718/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7JK67-1", "protein_name": "Calcium-binding protein 4 isoform X1", "gene_name": "Cabp4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z725" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z725", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z725" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z725", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z725" } ], "pmid": "" }, { "name": "meiotic gene conversion", "id": "GO:0006311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z725", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z725" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z725", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z725" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 615, "end_pos": 617 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z734-1", "uniprot_ac": "A0A8V0Z734", "uniprot_id": "A0A8V0Z734_CHICK", "mass": { "chemical_mass": 22115.0, "monoisotopic_mass": 22115.0 }, "refseq": {}, "gene_names": [ { "name": "FAM174B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z734" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 174 member B", "type": "synonym", "evidence": [ { "id": "A0A8V0Z734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z734/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z734", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z734" } ], "common_name": "Chicken", "glygen_name": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z737-1", "uniprot_ac": "A0A8V0Z737", "uniprot_id": "A0A8V0Z737_CHICK", "mass": { "chemical_mass": 29092.0, "monoisotopic_mass": 29092.0 }, "refseq": { "ac": "XP_415018", "name": "transcription factor Ovo-like 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415018" }, "gene_names": [ { "name": "OVOL3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ] }, { "name": "OVOL3", "type": "synonym", "evidence": [ { "id": "XP_415018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415018" } ] } ], "protein_names": [ { "name": "Ovo like zinc finger 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737/entry#names_and_taxonomy" } ] }, { "name": "transcription factor Ovo-like 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415018.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OVOL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z737", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z737", "database": "AlphaFoldDB", "categories": [] }, { "id": "416720", "url": "https://www.ncbi.nlm.nih.gov/gene/416720", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416720", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416720", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVSLDCM", "url": "https://omabrowser.org/oma/group/PVSLDCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z737", "url": "https://www.orthodb.org/?gene=A0A8V0Z737", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032:SF193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032:SF193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z737-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAFLVKRRSPQPAVRSWAGLPDDERADTYIPGGLGCAPGYEDSCSLESSGSSGTRDPELGDPPTPQAAPAELGAPGGMLLDLAVRRPAVRSKIKFTTGTCTDAAVHSCELCGKGFRLQRMLNRHIKCHSQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVSSVHPSSAFLKKTSKKLAAVLQNKLSPVLQRNSKDDDKDE", "length": 262, "header": "tr|A0A8V0Z737-1|A0A8V0Z737_CHICK Isoform 1 of Ovo like zinc finger 3 OS=Gallus gallus OX=9031 GN=OVOL3 PE=3 SV=1 CANONICAL=A0A8V0Z737-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z737-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737/entry#A0A8V0Z737-1", "sequence": { "sequence": "MPRAFLVKRRSPQPAVRSWAGLPDDERADTYIPGGLGCAPGYEDSCSLESSGSSGTRDPELGDPPTPQAAPAELGAPGGMLLDLAVRRPAVRSKIKFTTGTCTDAAVHSCELCGKGFRLQRMLNRHIKCHSQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVSSVHPSSAFLKKTSKKLAAVLQNKLSPVLQRNSKDDDKDE", "length": 262, "header": "tr|A0A8V0Z737-1|A0A8V0Z737_CHICK Isoform 1 of Ovo like zinc finger 3 OS=Gallus gallus OX=9031 GN=OVOL3 PE=3 SV=1 CANONICAL=A0A8V0Z737-1" }, "locus": { "chromosome": "3", "start_pos": 15152518, "end_pos": 15147144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045139.1", "url": "https://www.ensembl.org/id/ENSGALT00010045139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026960.1", "url": "https://www.ensembl.org/id/ENSGALP00010026960.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416720", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416720", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GIM7-1", "protein_name": "Ovo-like zinc finger 2", "gene_name": "Ovol2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKVFLVKRRSPGASVRSWDELPDDKRADTYIPVSLGCLLRDPPEDCRSDGGSSSGCSCSAGEPGGAESSSSPRAPEPETPELHDAEGTDGHLAAMQRPVARSKIKFTTGTCNDSVIHNCDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCYKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSTFLKKTSKKLAALMQNKLTSPLQENSTLSEEEEKK", "length": 274 }, "evidence": [ { "id": "A0A8V0Z737", "url": "https://omabrowser.org/oma/group/A0A8V0Z737/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CIV7-1", "protein_name": "Transcription factor Ovo-like 2", "gene_name": "Ovol2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKVFLVKRRSPGVSVRSWDELPDDKRADTYIPVSLGCLLRDPPEDCRSDGGSSSGCSSSAGEPGGAESSSSPRAPEPETPELHDAQGTDGHLAAMQRPVARSKIKFTTGTCDNSVIHNCDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSDHPGSTFLKKTSKKLAALMQNKLTSPLQENSTLSEEEEKK", "length": 274 }, "evidence": [ { "id": "A0A8V0Z737", "url": "https://omabrowser.org/oma/group/A0A8V0Z737/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRP0-1", "protein_name": "Transcription factor Ovo-like 2", "gene_name": "OVOL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKVFLVKRRSLGVSVRSWDELPDEKRADTYIPVGLGRLLHDPPEDCRSDGGSSSGSGSSSAGEPGGAESSSSPHAPESETPEPGDAEGPDGHLATKQRPVARSKIKFTTGTCSDSVVHSCDLCGKGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSSFLKKTSKKLAALLQGKLTSAHQENTSLSEEEERK", "length": 275 }, "evidence": [ { "id": "A0A8V0Z737", "url": "https://omabrowser.org/oma/group/A0A8V0Z737/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "epidermal cell differentiation", "id": "GO:0009913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009913", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], 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"UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z737", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z737" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 135, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 66 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z765-1", "uniprot_ac": "A0A8V0Z765", "uniprot_id": "A0A8V0Z765_CHICK", "mass": { "chemical_mass": 17561.0, "monoisotopic_mass": 17561.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z765", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z765", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z765", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z765", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z765-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKQNSITNPTNTDSNSAVLPRGQGGPRDAPREPHCPGLGPVSFHRGAAQVEALTVPVLHSVDHLLRHTHGEGEVAAHLPHHDGGANVLGLDLDVLARHLLGDLQAVGSVLVAAVLGAISKGSRELVHLCLVHFLLHAFLEALEDDGELRDEKDQKERGYKMTT", "length": 164, "header": "tr|A0A8V0Z765-1|A0A8V0Z765_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z765-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z765-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z765/entry#A0A8V0Z765-1", "sequence": { "sequence": "MKKQNSITNPTNTDSNSAVLPRGQGGPRDAPREPHCPGLGPVSFHRGAAQVEALTVPVLHSVDHLLRHTHGEGEVAAHLPHHDGGANVLGLDLDVLARHLLGDLQAVGSVLVAAVLGAISKGSRELVHLCLVHFLLHAFLEALEDDGELRDEKDQKERGYKMTT", "length": 164, "header": "tr|A0A8V0Z765-1|A0A8V0Z765_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z765-1" }, "locus": { "chromosome": "10", "start_pos": 14688626, "end_pos": 14687852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044876.1", "url": "https://www.ensembl.org/id/ENSGALT00010044876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026795.1", "url": "https://www.ensembl.org/id/ENSGALP00010026795.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z768-1", "uniprot_ac": "A0A8V0Z768", "uniprot_id": "A0A8V0Z768_CHICK", "mass": { "chemical_mass": 54127.0, "monoisotopic_mass": 54127.0 }, "refseq": { "ac": "XP_421675", "name": "centrosomal protein of 55 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421675" }, "gene_names": [ { "name": "CEP55", "type": "recommended", "evidence": [ { "id": "A0A8V0Z768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ] }, { "name": "CEP55", "type": "synonym", "evidence": [ { "id": "XP_421675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421675" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 55 kDa", "type": "recommended", "evidence": [ { "id": "A0A8V0Z768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 55 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421675" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421675.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421675" } ] }, { "annotation": "Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation. Plays a role in the development of the brain and kidney.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768#function" }, { "database": "UniProtKB", "id": "ARBA00055531", "url": "https://www.uniprot.org/uniprotkb/ARBA00055531#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768", "locus": { "chromosome": "6", "start_pos": 21206157, "end_pos": 21220980, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020370", "url": "https://www.ensembl.org/id/ENSGALG00010020370" } ] } } ], "crossref": [ { "id": "A0A8V0Z768", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z768", "database": "AlphaFoldDB", "categories": [] }, { "id": "423804", "url": "https://www.ncbi.nlm.nih.gov/gene/423804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AVMAKCS", "url": "https://omabrowser.org/oma/group/AVMAKCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z768", "url": "https://www.orthodb.org/?gene=A0A8V0Z768", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31838", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31838", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31838:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31838:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z768-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSKTTKGVIIGKWGLKSGSSRPESELEKYKQENAALRKSLEEATKGKGRAEDPERIRLLEKILCLEKEKEKYNHLLGEKDKEIQNLRDRLKSKNKNSEVSSLHSQLEEKTKEAERREQLLSSLSEEMNRLKCNLSTITAKCSEIESRTGSSQAFQEAVTNSPGSSTNHSEVEKQLKDALEKNQQWLLYDQQREAYVRGLLGRIFELEQRSEIVSQQQPKESNAEGHLQEEKQKHYDQLLQNAKSDLEAERCTVTQLKCELNEFKKKYEQRRQEIMSLNALLQSQQVVDMKDQENENKIQGEKIQILKQENESIKVQLREEKKKSEDLLSQVQLLRKSLLKQQEEHARIALLEKQIQMCTADLENEKLDRQNLKHQLNKIFKELIKAREQITRLEPLKLQECGLMEPQEDLQAAFEEKITTYDISPSLKHSNLLDESFLECPRCQVQYPTSQHRELLAHIDFCTA", "length": 465, "header": "tr|A0A8V0Z768-1|A0A8V0Z768_CHICK Isoform 1 of Centrosomal protein of 55 kDa OS=Gallus gallus OX=9031 GN=CEP55 PE=4 SV=1 CANONICAL=A0A8V0Z768-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z768-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768/entry#A0A8V0Z768-1", "sequence": { "sequence": "MNSKTTKGVIIGKWGLKSGSSRPESELEKYKQENAALRKSLEEATKGKGRAEDPERIRLLEKILCLEKEKEKYNHLLGEKDKEIQNLRDRLKSKNKNSEVSSLHSQLEEKTKEAERREQLLSSLSEEMNRLKCNLSTITAKCSEIESRTGSSQAFQEAVTNSPGSSTNHSEVEKQLKDALEKNQQWLLYDQQREAYVRGLLGRIFELEQRSEIVSQQQPKESNAEGHLQEEKQKHYDQLLQNAKSDLEAERCTVTQLKCELNEFKKKYEQRRQEIMSLNALLQSQQVVDMKDQENENKIQGEKIQILKQENESIKVQLREEKKKSEDLLSQVQLLRKSLLKQQEEHARIALLEKQIQMCTADLENEKLDRQNLKHQLNKIFKELIKAREQITRLEPLKLQECGLMEPQEDLQAAFEEKITTYDISPSLKHSNLLDESFLECPRCQVQYPTSQHRELLAHIDFCTA", "length": 465, "header": "tr|A0A8V0Z768-1|A0A8V0Z768_CHICK Isoform 1 of Centrosomal protein of 55 kDa OS=Gallus gallus OX=9031 GN=CEP55 PE=4 SV=1 CANONICAL=A0A8V0Z768-1" }, "locus": { "chromosome": "6", "start_pos": 21220754, "end_pos": 21208130, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049205.1", "url": "https://www.ensembl.org/id/ENSGALT00010049205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029091.1", "url": "https://www.ensembl.org/id/ENSGALP00010029091.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JB98-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "LOC113833727", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSRSPKDLIKCKWGSRPSSSKSDTALEKFKGEIAAFKTSLDEITSGKGKVTDRDKCRLLEKIQVLEAEREKNVYYLTEKDKEIQRLKDQLKARYSSSSLLEQLEEKTKECGKKQQLLESLSKETDVLKKQLSAMTKRLSELESKACTLNLSQSVPANCFNSSMSSIHEKEMQLKDALEKNQQWLVYDQQREAYVKGLLAKIFELEKRKETAATLLPQQMKKTESEGYLQEEKKKYDHLLENAKKDLEVERQTVTQLRSELDEFRRKYEETQKEVEDLNQLLSSQRKADIEHLEEDRHKTEKIQRLREESSIFKGKLEEERKKSEELLSQVRILYESLLKHQEEQTRVALLEQQMQACTLDFENEKLDRQNMQHQLYVILKELRKARSQITQLESLKQLHGFAFTEQSFPIQREPESRVKVTSPKSPTAALNESLVECPNCSVQYPANEHRDLLVHVEYCTK", "length": 462 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SC81-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "CEP55", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSRSPKELIKSKWGSKPSNSKSETALERFRGEIAALKTSVDEITSGKGKLTDKDRHRLLEKIRVLEAEREKNAYCLTEKDKEIQRLRDQLKAKYSTTALLEQLEEKTKEGERREQLLKSLSEETDVLKKQLSATTARLAELEGKASTLRLSQTVATSCLNPSMSEIHEMEVQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEQQKSETAAHVLPQQTKKTESEGYLQEEKQKYYNHLLVNAKKDLEVERQTVTQLNFELSEFRRKYEETQKEVQDLNQLLCLQRKADVQHLEDDRHKTEKIQRLKEENDLAREKLGEEKKRSEELLSQVQFLYTSLLKQQEEQTKVALLEQQIQACTLDFENEKLDRQNMQHQLHVILKELRKARNQITQLESLKQFREFAFTEPLVTFQGETENRGKVASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK", "length": 464 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V7C8-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "Cep55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRSPKDLIKSKWGSRPSSSKSDTALEKFKGEIAAFKTSLDEITNGKGKVANKDRSKLLEKIQVLEAEREKNVYYLMEKDKEIQRLKDHLRSRYSSSSLLEQLEEKTKECEKKQQLLESLSRETDILKKQLSATTKRLSELESKASTLHLSQSVPANCFNSSMNSIHEKEMQLKDALEKNQQWLVYDQQREAYVKGLLAKIFELEKRTETAAASLPQQMKKTESEGYLQEEKQKYDHLLENAKKDLEVERQTVTQLRLELDEFRRKYEETQKEVEDLNQLLSSQRKADIQHLEEDKHKTEKIQKLREESSVFKGKLEEERKKSEELLSQVRILYDSLLKHQEEQSRVALLERQMQACTLDFENEKLDRQNMQHQLYVILKELRKAKSQITQLESLKQLHGFTFTEQPFPLQGEPENRVKATSPKSPTAVLNESLVECPKCSVQYPATEHRDLLVHVEYCMK", "length": 462 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q502I3-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "cep55", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAKGAKETLVNKLGFKSSSSSSKSAELEVEKLKRENQQMKKSLEDMKRAGRHQHTHPDTDKARLLERILALETLREKNNQQLLGREQEITTLRQQLRSAHGEVVSSLQSQLENKQHEAEQRERQYQALVKETEDLKNKYCAVSERCDTLEKQKGSSGELAVVQEQLRDALEKNQHWLVYDQQREAYVQGVLARIKDLEAQLNEANQALQQQHKEAKSDDQSAQKVQQELEAERNKVSRMQMEVEDLQVRYEEKSREAAQAREQLLEERRREREDRKSSVERDALLQDQHRKREAELIMQVNLLQKSLMNQKEEQKRMAILEQQIQLSAKESENEKLDRQTLQHQLHKVLKELRKARDQITRLESSKQQRESRFSEPSSYNRMDLERLTIQDHMTSPSKVHNILDESVLECPNCGASYPTSQHRELLAHLDYCFT", "length": 435 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q53EZ4-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "CEP55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSRSTKDLIKSKWGSKPSNSKSETTLEKLKGEIAHLKTSVDEITSGKGKLTDKERHRLLEKIRVLEAEKEKNAYQLTEKDKEIQRLRDQLKARYSTTTLLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK", "length": 464 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BT07-1", "protein_name": "Centrosomal protein of 55 kDa", "gene_name": "Cep55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSRSPKDLIKSKWGSRPSSSKSDTALEKFKGEIAAFKTSLDEITSGKGKMAEKGRSRLLEKIQVLEAEREKNVYYLLEKDKEIQRLKDHLRSRYSSSSLFEQLEEKTKECEKKQQLLESLSKETDVLKNQLSATTKRLSELESKASTLHLSQSMPANCFNSSMNSIHEKEMQLKDALEKNQQWLVYDQQREAYVKGLLAKIFELEKRTETAAASLTQQMKKIESEGYLQVEKQKYDHLLENAKKDLEVERQAVTQLRLELDEFRRKYEEARKEVEDLNQLLSSQRKADIQHLEEDKQKTERIQKLREESSIFKGKLEEERKRSEELLSQVRILYDSLLKHQEEQARVALLEQQMQACTLDFENEKLDRQNMQHQLYVILKELRKAKSQITQLESLKQLHGFTITEQPFPLQREPESRVKATSPKSPSAALNDSLVECPKCSVQYPATEHRDLLVHVEYCMK", "length": 462 }, "evidence": [ { "id": "A0A8V0Z768", "url": "https://omabrowser.org/oma/group/A0A8V0Z768/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z768", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z768" }, { "id": "PF12180", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TSG101 and ALIX binding", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 206, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z780-1", "uniprot_ac": "A0A8V0Z780", "uniprot_id": "A0A8V0Z780_CHICK", "mass": { "chemical_mass": 25439.0, "monoisotopic_mass": 25439.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100857817", "type": "recommended", "evidence": [ { "id": "A0A8V0Z780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z780", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100857817", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z780", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z780", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8V0Z780-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAVSPALLLLLSLGLCCTSTQAQRNTMEARFLDRNMKNPQEGQRLELECLHYERNRPVFWIRLDKSGNLHFIVSSTHSYSTTLREGEKTSPNFEALWRGNSYRLVVKSFRAQDEGIYYCINYINPVLHFSSGQPAFFPAEHIAPAATIQSSQVTTKDNSQQDQDAGTSNENALHFCYDVVIWVNLAGACLLLLTAITITITHCQSKSHSDTLQRFLEPHTTEHS", "length": 225, "header": "tr|A0A8V0Z780-1|A0A8V0Z780_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857817 PE=4 SV=1 CANONICAL=A0A8V0Z780-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z780-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780/entry#A0A8V0Z780-1", "sequence": { "sequence": "MMAVSPALLLLLSLGLCCTSTQAQRNTMEARFLDRNMKNPQEGQRLELECLHYERNRPVFWIRLDKSGNLHFIVSSTHSYSTTLREGEKTSPNFEALWRGNSYRLVVKSFRAQDEGIYYCINYINPVLHFSSGQPAFFPAEHIAPAATIQSSQVTTKDNSQQDQDAGTSNENALHFCYDVVIWVNLAGACLLLLTAITITITHCQSKSHSDTLQRFLEPHTTEHS", "length": 225, "header": "tr|A0A8V0Z780-1|A0A8V0Z780_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100857817 PE=4 SV=1 CANONICAL=A0A8V0Z780-1" }, "locus": { "chromosome": "4", "start_pos": 85398397, "end_pos": 85396019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041549.1", "url": "https://www.ensembl.org/id/ENSGALT00010041549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024323.1", "url": "https://www.ensembl.org/id/ENSGALP00010024323.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z780", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ], "pmid": "" }, { "name": "T cell mediated immunity", "id": "GO:0002456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z780", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ], "pmid": "" }, { "name": "cytotoxic T cell differentiation", "id": "GO:0045065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z780", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z780", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z780" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 120, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z788-1", "uniprot_ac": "A0A8V0Z788", "uniprot_id": "A0A8V0Z788_CHICK", "mass": { "chemical_mass": 32926.0, "monoisotopic_mass": 32926.0 }, "refseq": {}, "gene_names": [ { "name": "MFAP2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788" } ] } ], "protein_names": [ { "name": "Microfibril associated protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z788", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788", "locus": { "chromosome": "21", "start_pos": 4404659, "end_pos": 4410383, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020382", "url": "https://www.ensembl.org/id/ENSGALG00010020382" } ] } } ], "crossref": [ { "id": "A0A8V0Z788", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z788", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858555", "url": "https://www.ncbi.nlm.nih.gov/gene/100858555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z788", "url": "https://www.orthodb.org/?gene=A0A8V0Z788", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD22", "url": "https://www.orthodb.org/?gene=A0A8V0ZD22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE36", "url": "https://www.orthodb.org/?gene=A0A8V0ZE36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZEG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKI1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKI6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16485:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16485:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05507", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05507", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1566948", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z788", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z788-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPPLGPPRSACWPKCAYPTSVCANPNRLALPKPIGVGSQRLHYLQNWMGVDPQFPLSISGLGSPSHATKLPPGWTDGCIPNRCIVLVILLPTFTVFSLCPHPDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 296, "header": "tr|A0A8V0Z788-1|A0A8V0Z788_CHICK Isoform 1 of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z788-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0Z788-1", "sequence": { "sequence": "MGPPLGPPRSACWPKCAYPTSVCANPNRLALPKPIGVGSQRLHYLQNWMGVDPQFPLSISGLGSPSHATKLPPGWTDGCIPNRCIVLVILLPTFTVFSLCPHPDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 296, "header": "tr|A0A8V0Z788-1|A0A8V0Z788_CHICK Isoform 1 of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4406981, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049249.1", "url": "https://www.ensembl.org/id/ENSGALT00010049249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029112.1", "url": "https://www.ensembl.org/id/ENSGALP00010029112.1" } ] } }, { "isoform_ac": "A0A8V0ZD22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZD22-1", "sequence": { "sequence": "MLQWGSTVCGRGGGGREGSGVALGPSGAPMLEVGAFFSFSPPPSPPPIPHFEVFEPGEKKPKRWVKARAARCTRSDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 268, "header": "tr|A0A8V0ZD22-1|A0A8V0ZD22_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4409199, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049261.1", "url": "https://www.ensembl.org/id/ENSGALT00010049261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029119.1", "url": "https://www.ensembl.org/id/ENSGALP00010029119.1" } ] } }, { "isoform_ac": "A0A8V0ZE36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZE36-1", "sequence": { "sequence": "MLEVGAFFSFSPPPSPPPIPHFEVFEPGEKKPKRWVKARAARCTRSDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQADVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 230, "header": "tr|A0A8V0ZE36-1|A0A8V0ZE36_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4408633, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049253.1", "url": "https://www.ensembl.org/id/ENSGALT00010049253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029116.1", "url": "https://www.ensembl.org/id/ENSGALP00010029116.1" } ] } }, { "isoform_ac": "A0A8V0ZEG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZEG6-1", "sequence": { "sequence": "MLGFFDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 198, "header": "tr|A0A8V0ZEG6-1|A0A8V0ZEG6_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4407870, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049252.1", "url": "https://www.ensembl.org/id/ENSGALT00010049252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029115.1", "url": "https://www.ensembl.org/id/ENSGALP00010029115.1" } ] } }, { "isoform_ac": "A0A8V0ZEH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZEH1-1", "sequence": { "sequence": "MSLRAEALIVQPVSLQHGRMEGDACSWRQHCLRARRRRKGRIRCRFRTQRSPHVGDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 248, "header": "tr|A0A8V0ZEH1-1|A0A8V0ZEH1_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4410184, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049262.1", "url": "https://www.ensembl.org/id/ENSGALT00010049262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029120.1", "url": "https://www.ensembl.org/id/ENSGALP00010029120.1" } ] } }, { "isoform_ac": "A0A8V0ZKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZKI1-1", "sequence": { "sequence": "MCTAKTSGSAEPIDPQPPPPPPPPAGHPMGFGGDGVGCEGAVPTPPPPIPLHNPVPLGGKSQWWMAAVERPPWFAAGMGDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 272, "header": "tr|A0A8V0ZKI1-1|A0A8V0ZKI1_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4407584, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049250.1", "url": "https://www.ensembl.org/id/ENSGALT00010049250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029113.1", "url": "https://www.ensembl.org/id/ENSGALP00010029113.1" } ] } }, { "isoform_ac": "A0A8V0ZKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z788/entry#A0A8V0ZKI6-1", "sequence": { "sequence": "MLEKPKRWVKARAARCTRSDCAVLLQLPPITMRALCLVLLGLPALLVQGQYSRFEGITYPEPVQYSQYDQQAEIQDYYDYHDVTPRTPEEQFRFQSQQQSQQEVVPAPTMAAVPETEPTEPGPLDCREEQYPCTRLYSVHKPCKQCLNEICFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMATSGLCQTVVTSCARSCGGC", "length": 212, "header": "tr|A0A8V0ZKI6-1|A0A8V0ZKI6_CHICK Computationally mapped isoform of Microfibril associated protein 2 OS=Gallus gallus OX=9031 GN=MFAP2 PE=1 SV=1 CANONICAL=A0A8V0Z788-1" }, "locus": { "chromosome": "21", "start_pos": 4408633, "end_pos": 4405061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049257.1", "url": "https://www.ensembl.org/id/ENSGALT00010049257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029118.1", "url": "https://www.ensembl.org/id/ENSGALP00010029118.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139350" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9", "locus": { "chromosome": "3", "start_pos": 21946034, "end_pos": 21923831, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018807", "url": "https://www.ensembl.org/id/ENSGALG00010018807" } ] } } ], "crossref": [ { "id": "A0A8V0Z7E9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7E9", "database": "AlphaFoldDB", "categories": [] }, { "id": "421378", "url": "https://www.ncbi.nlm.nih.gov/gene/421378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421378", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNFRSRI", "url": "https://omabrowser.org/oma/group/MNFRSRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7E9", "url": "https://www.orthodb.org/?gene=A0A8V0Z7E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z806", "url": "https://www.orthodb.org/?gene=A0A8V0Z806", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28489:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28489:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z806", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z806", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z806-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z806-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLASWFRWNEPPNRISQRNPTEMVVETLMMELSWQIKQAEKQQRERENEYRKIKTGVDYGWLVSYPKQSYDISPGERLQLEDMCTKIHPSYCGPVILRFRQLIAEYEPEVQEVSRLFRSVLQEAVEKIKEEEDAKKLAKQWNTKNKTSLSLTTFKSRSKISPFISDIKTISEDVERGTQPTRRVWSMPEFRNAKDY", "length": 197, "header": "tr|A0A8V0Z7E9-1|A0A8V0Z7E9_CHICK Isoform 1 of RD3 regulator of GUCY2D OS=Gallus gallus OX=9031 GN=RD3 PE=4 SV=1 CANONICAL=A0A8V0Z7E9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9/entry#A0A8V0Z7E9-1", "sequence": { "sequence": "MSLASWFRWNEPPNRISQRNPTEMVVETLMMELSWQIKQAEKQQRERENEYRKIKTGVDYGWLVSYPKQSYDISPGERLQLEDMCTKIHPSYCGPVILRFRQLIAEYEPEVQEVSRLFRSVLQEAVEKIKEEEDAKKLAKQWNTKNKTSLSLTTFKSRSKISPFISDIKTISEDVERGTQPTRRVWSMPEFRNAKDY", "length": 197, "header": "tr|A0A8V0Z7E9-1|A0A8V0Z7E9_CHICK Isoform 1 of RD3 regulator of GUCY2D OS=Gallus gallus OX=9031 GN=RD3 PE=4 SV=1 CANONICAL=A0A8V0Z7E9-1" }, "locus": { "chromosome": "3", "start_pos": 21942300, "end_pos": 21934416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045405.1", "url": "https://www.ensembl.org/id/ENSGALT00010045405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027095.1", "url": "https://www.ensembl.org/id/ENSGALP00010027095.1" } ] } }, { "isoform_ac": "A0A8V0Z806-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9/entry#A0A8V0Z806-1", "sequence": { "sequence": "GDAGRGRASCSELGNVGTVCLAPAFFLVCSKRGLGCAVQSCEEPEGLSNSREAPAGRHAARPSGGRSPGSPRAALRAQPPALVTRLIRTRCKCAVPERSASLRAAPSSGFPRGPVRVSVRPHEQRSRRFRQLIAEYEPEVQEVSRLFRSVLQEAVEKIKEEEDAKKLAKQWNTKNKTSLSLTTFKSRSKISPFISDIKTISEDVERGTQPTRRVWSMPEFRNAKDY", "length": 226, "header": "tr|A0A8V0Z806-1|A0A8V0Z806_CHICK Computationally mapped isoform of RD3 regulator of GUCY2D OS=Gallus gallus OX=9031 GN=RD3 PE=4 SV=1 CANONICAL=A0A8V0Z7E9-1" }, "locus": { "chromosome": "3", "start_pos": 21942300, "end_pos": 21923835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045408.1", "url": "https://www.ensembl.org/id/ENSGALT00010045408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027097.1", "url": "https://www.ensembl.org/id/ENSGALP00010027097.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZR16-1", "protein_name": "RD3 regulator of GUCY2D", "gene_name": "RD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLTPWLRWHAAPPRLSSRSPAEMVLETLMVELAGQMREAERQQWERSKAVRKICTGVDYSWLASAPRPAYDLSPGERLQLEDVCAKIHPSYCGPAILRFRQLMAEREPEVQEGSRLFRSVLQEVLERMKQEEAAHKLTRQWSLRPRGGLAPFKGRARIAPFASDIRTISEDVERDAPPPSRTWSMPEFRARKED", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BP94-1", "protein_name": "RD3 regulator of GUCY2D", "gene_name": "RD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLLPWLRGNEAPPRPSPRSPAEMVLETLMVELAGQMREAERQQRERSHAVRKVCTRVDYSWLASAPRPAYDLSPGERLQLEDVCAKIHPAYCGPAILRFRQLVAEQEPEVQEVSRLFRSVLQEVLERMEEEEEAQRLTRQWSLRAPRGTLTTFRSRARIAPFASDIHTISEDVERDTPPPRAWSLPEFRARKED", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H2L4-1", "protein_name": "Protein RD3 isoform X1", "gene_name": "Rd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLTPWLRWNDTPPRLSARSPAEIVLETLMMELAGQMREVERQQRERRRAVRKICTGVDYSWLASAPRPSYDLSPGERLQLEDVCAKIHPSYCGPAILRFRQLLAEREPEVQDVARLFRSVLQEALEKTKQEEEAHKLTRQWSLRPRGSLSSFKTRARIAPFASDIRTISEDVERDAPPPPRTWSMPEFRAPQVD", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R688-1", "protein_name": "RD3 regulator of GUCY2D", "gene_name": "Rd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLIPWLRWNDTPPRLSARSPAEMVLETLMMELAGQMREVERQQRERRSAVRKICTGVDYSWLASAPRPTYDISPGERLQLEDVCAKIHPSYCGPAILRFRQLLAEREPEVQEVARLFRSVLQEALEKMKQEEEAHKLTRQWSLRPRGSLSSFKTRARIAPFASDIRTISEDVERDAPPPPRTWSMPEFRAPQAD", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3Z2-1", "protein_name": "Protein RD3", "gene_name": "RD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLISWLRWNEAPSRLSTRSPAEMVLETLMMELTGQMREAERQQRERSNAVRKVCTGVDYSWLASTPRSTYDLSPIERLQLEDVCVKIHPSYCGPAILRFRQLLAEQEPEVQEVSQLFRSVLQEVLERMKQEEEAHKLTRQWSLRPRGSLATFKTRARISPFASDIRTISEDVERDTPPPLRSWSMPEFRAPKAD", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BRE0-1", "protein_name": "Protein RD3", "gene_name": "Rd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLIPWLRWNDTPPRLSARTPAEMVLETLMMELAGQMREVERQQRERRSAVRKICTGVDYSWLANTPRPTYDISPGERLQLEDVCAKIHPSYCGPAILRFRQLLAEREPEVQEVARLFRSVLQEALEKMKQEEEAHKLTRQWSLRPRGSLSSFKTRARIAPFASDIRTISEDVERDAPPPPRTWSMPEFRAPQAD", "length": 195 }, "evidence": [ { "id": "A0A8V0Z7E9", "url": "https://omabrowser.org/oma/group/A0A8V0Z7E9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"Protein Classification", "Other" ] }, { "id": "A0A8V0YTX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z090", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z090", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z090-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z090-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z226", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z226", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z226-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z226-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEAVETMTSWNMTWLWKLLTKSSFESINLHTELKGCFGVLDDLQDFLGHYTSTSLLCVSFTSTQINALLFFCSPSE", "length": 1549, "header": "tr|A0A8V0Z7P5-1|A0A8V0Z7P5_CHICK Isoform 1 of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0YTX4-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEQKFLEMPIQAMVRCLWLNWNHNPFQTLFCKLPNQAAEWHLSQRVPLRKKAKEMHELCDPELFM", "length": 1405, "header": "tr|A0A8V0YTX4-1|A0A8V0Z7P5_CHICK Computationally mapped isoform of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54764608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041868.1", "url": "https://www.ensembl.org/id/ENSGALT00010041868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024489.1", "url": "https://www.ensembl.org/id/ENSGALP00010024489.1" } ] } }, { "isoform_ac": "A0A8V0Z090-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0Z090-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEASELYSGSHKYMGR", "length": 1489, "header": "tr|A0A8V0Z090-1|A0A8V0Z7P5_CHICK Computationally mapped isoform of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54761373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041828.1", "url": "https://www.ensembl.org/id/ENSGALT00010041828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024461.1", "url": "https://www.ensembl.org/id/ENSGALP00010024461.1" } ] } }, { "isoform_ac": "A0A8V0Z0N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0Z0N4-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEAPLSSSINPPIVSLSRSKEGFHTM", "length": 1499, "header": "tr|A0A8V0Z0N4-1|A0A8V0Z7P5_CHICK Computationally mapped isoform of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54757257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041838.1", "url": "https://www.ensembl.org/id/ENSGALT00010041838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024468.1", "url": "https://www.ensembl.org/id/ENSGALP00010024468.1" } ] } }, { "isoform_ac": "A0A8V0Z226-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0Z226-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEGVVPHFHSHVSAERMSVKLPSMNIDDQTQSLSSIHGDSDSSGADTF", "length": 1522, "header": "tr|A0A8V0Z226-1|A0A8V0Z7P5_CHICK Computationally mapped isoform of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54741517, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041873.1", "url": "https://www.ensembl.org/id/ENSGALT00010041873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024492.1", "url": "https://www.ensembl.org/id/ENSGALP00010024492.1" } ] } }, { "isoform_ac": "A0A8V0Z7M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0Z7M4-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEASNNSDGIVMLRLFISGKKSPQPMLWSWDLEPNCKTMDYI", "length": 1516, "header": "tr|A0A8V0Z7M4-1|A0A8V0Z7M4_CHICK Computationally mapped isoform of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54763376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041822.1", "url": "https://www.ensembl.org/id/ENSGALT00010041822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024455.1", "url": "https://www.ensembl.org/id/ENSGALP00010024455.1" } ] } }, { "isoform_ac": "A0A8V0Z7P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5/entry#A0A8V0Z7P5-1", "sequence": { "sequence": "MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAGAGGRNSAAVSVTKLREALPSRQAAGVALSRGETPCEPPVPSSGASSGRVTGVTACSAAPGVWNAKGHPEHLLLVADPVEAMSVPQMVYPKEAAVNPKEADRSLQPEYSRRPKDDVLISRYPTGQKEALRAVLKQKTRSAPVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAAIATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTRTQHEKPHCHERVSELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGLQQTHMPSSSLLTKQSEKAEEQLLNNGISSSQKNFFPSSGLPTQGDGRHLEHILNPQAAPWGQMESSEKTMLTNDKMSWHSEIERPTALQTDSCPAYENSSQNCNSIEKTVKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSKPATIASDPPEYNHLVKPSVLQNVKAPNSILSDAKRVLREVQSRKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMARNDMEQVKYDQKVPWIKRAQNIKAMKNSKEIKAKTQKIQGCSTKKPLSAAKSLRNHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYLSQIYGKPIYQGHRSTLKKAPYLRFNSPSPKSKLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVISSKKQHPLYALAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVTVTTSIPQVPPKPPTEVKKPKVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVNHVLPEPKPARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEIPEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQSCDVLDEWIERRETIENRLINWVEQEIMAKIISEMYPVQRETVPSVSTSEGEDSETVTSDIVEAAGGGGFQLFIDAGVPVDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTAVMEPLVPTPLPTPQATPPQTPPSEKEMPPVQTPESSPSITELSGDVREQEKMKEAGSDIPAAVSRVGTPVITPISTPPEIITPSPPASEAAKMENPAPLNPWDDAELPLEEEKPSPLAEETFNPKAVEMSVANDEEPEALILPSWQSSPKPFQSLPCEPEAPSAAPTDSSEQSTQESSLTPTETETADRPISEGEVLFSCDQMLAGREGGLSFPNLTESLTSTLQDANEMDYDPPSEGQVVRRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHLEDSDSSVGELSEGQRPRLTRAAERILMGHPVDIDHATARASEDRPYQGSRSPSPGQLTHPAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVASLPKGPSQEESQGDARVVRPRVVHVRRKSEEMQEEAVETMTSWNMTWLWKLLTKSSFESINLHTELKGCFGVLDDLQDFLGHYTSTSLLCVSFTSTQINALLFFCSPSE", "length": 1549, "header": "tr|A0A8V0Z7P5-1|A0A8V0Z7P5_CHICK Isoform 1 of TALPID3 OS=Gallus gallus OX=9031 GN=TA3 PE=4 SV=1 CANONICAL=A0A8V0Z7P5-1" }, "locus": { "chromosome": "5", "start_pos": 54805547, "end_pos": 54742999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041847.1", "url": "https://www.ensembl.org/id/ENSGALT00010041847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024475.1", "url": "https://www.ensembl.org/id/ENSGALP00010024475.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1079, "start_aa": "Thr", "end_pos": 1079, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1079", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1083, "start_aa": "Thr", "end_pos": 1083, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1083", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1282, "end_pos": 1284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1484, "end_pos": 1486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1079, 1083 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1282, "end_pos": 1284 }, { "start_pos": 1484, "end_pos": 1486 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 893, "end_pos": 895 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7S4-1", "uniprot_ac": "A0A8V0Z7S4", "uniprot_id": "A0A8V0Z7S4_CHICK", "mass": { "chemical_mass": 45258.0, "monoisotopic_mass": 45258.0 }, "refseq": { "ac": "NP_001265083", "name": "methyltransferase-like protein 22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" }, "gene_names": [ { "name": "METTL22", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ] }, { "name": "C14H16orf68", "type": "synonym", "evidence": [ { "id": "NP_001265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" } ] }, { "name": "C16orf68", "type": "synonym", "evidence": [ { "id": "NP_001265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" } ] }, { "name": "METTL22", "type": "synonym", "evidence": [ { "id": "NP_001265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" } ] } ], "protein_names": [ { "name": "Methyltransferase-like protein 22", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4/entry#names_and_taxonomy" } ] }, { "name": "methyltransferase-like protein 22", "type": "synonym", "evidence": [ { "id": "NP_001265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.196797.1, ERR2368565.115903.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992559 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Dec 3, 2021 this sequence version replaced NP_001265083.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083" } ] }, { "annotation": "Protein N-lysine methyltransferase. Trimethylates KIN at Lys-135 (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4#function" }, { "database": "UniProtKB", "id": "ARBA00059634", "url": "https://www.uniprot.org/uniprotkb/ARBA00059634#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4", "locus": { "chromosome": "14", "start_pos": 10118776, "end_pos": 10157862, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017361", "url": "https://www.ensembl.org/id/ENSGALG00010017361" } ] } } ], "crossref": [ { "id": "A0A8V0Z7S4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7S4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425865", "url": "https://www.ncbi.nlm.nih.gov/gene/425865", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425865", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425865", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYERIQQ", "url": "https://omabrowser.org/oma/group/AYERIQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTX9", "url": "https://www.orthodb.org/?gene=A0A8V0YTX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTY3", "url": "https://www.orthodb.org/?gene=A0A8V0YTY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7S4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23108:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23108:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YTX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDVTEKEMDNLTFKSDTVLSDVHLHRPNKSRLMVRLNAVGQPVFLSYFKLLWNTDDQASEKNARETTAEREHQYRSGDELPNKDGSNLKYKMEWNTEGTEALLDEDGDLEVVRRPQSASDSEAEDLMRDRVYPVILMRGKEDAFEDEEQECTCSNVIKIEHTMATPLEDVGKQVWRAAFLLADYILFKRDMFRSCTVLELGGGTGIASIIMGTVANRVYCTDVGEDLLAMCEQNVALNKHLMEPGGGEIKVKELDWLKDEFCTDPEALYSWSEEEIADLHDYCTVIMAADVFYDDDLTDALFRTLYRITHNLKHSCTVFLAIEKRLNFTLRQMDVTCEAYSHFRSTLNDLENLHDGKMKYSVEPVKPDFCQFLIYERIEQLELWKIIADQLT", "length": 393, "header": "tr|A0A8V0Z7S4-1|A0A8V0Z7S4_CHICK Isoform 1 of Methyltransferase-like protein 22 OS=Gallus gallus OX=9031 GN=METTL22 PE=3 SV=1 CANONICAL=A0A8V0Z7S4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4/entry#A0A8V0YTX9-1", "sequence": { "sequence": "MGDVTEKEMDNLTFKSDTVLSDVHLHRPNKSRLMVRLNAVGQPVFLSYFKLLWNTDDQASEKNARETTAEREHQYRSGDELPNKDGSNLKYKMEWNTEGTEALLDEDGDLEVVRRPQSASDSEAEDLMRDRVYPVILMRGKEDAFEDEEQECTCSNVIKIEHTMATPLEDVGKQVWRAAFLLADYILFKRDMFRSCTVLELGGGTGIASIIMGTVANRVYCTDVGEDLLAMCEQNVALNKHLMEPGGGEIKVKELDWLKDEFCTDPEALYSWSEEEIADLHDYCTVIMAADGRKI", "length": 295, "header": "tr|A0A8V0YTX9-1|A0A8V0Z7S4_CHICK Computationally mapped isoform of Methyltransferase-like protein 22 OS=Gallus gallus OX=9031 GN=METTL22 PE=3 SV=1 CANONICAL=A0A8V0Z7S4-1" }, "locus": { "chromosome": "14", "start_pos": 10130721, "end_pos": 10125341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041879.1", "url": "https://www.ensembl.org/id/ENSGALT00010041879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024494.1", "url": "https://www.ensembl.org/id/ENSGALP00010024494.1" } ] } }, { "isoform_ac": "A0A8V0YTY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4/entry#A0A8V0YTY3-1", "sequence": { "sequence": "MGDVTEKEMDNLTFKSDTVLSDVHLHRPNKSRLMVRLNAVGQPVFLSYFKLLWNTDDQASEKNARETTAEREHQYRSGDELPNKDGSNLKYKMEWNTEGTEALLDEDGDLEVVRRPQSASDSEAEDLMRDRVYPVILMRGKEDAFEDEEQECTCSNVIKIEHTMATPLEDVGKQVWRAAFLLADYILFKRDMFRSCTVLELGGGTGIASIIMGTVANRVYCTDVGEDLLAMCEQNVALNKHLMEPGEEEIADLHDYCTVIMAADVFYDDDLTDALFRTLYRITHNLKHSCTVFLAIEKRLNFTLRQMDVTCEAYSHFRSTLNDLENLHDGKMKYSVEPVKPDFCQFLIYERIEQLELWKIIADQLT", "length": 366, "header": "tr|A0A8V0YTY3-1|A0A8V0Z7S4_CHICK Computationally mapped isoform of Methyltransferase-like protein 22 OS=Gallus gallus OX=9031 GN=METTL22 PE=3 SV=1 CANONICAL=A0A8V0Z7S4-1" }, "locus": { "chromosome": "14", "start_pos": 10130721, "end_pos": 10121964, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041885.1", "url": "https://www.ensembl.org/id/ENSGALT00010041885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024499.1", "url": "https://www.ensembl.org/id/ENSGALP00010024499.1" } ] } }, { "isoform_ac": "A0A8V0Z7S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4/entry#A0A8V0Z7S4-1", "sequence": { "sequence": "MGDVTEKEMDNLTFKSDTVLSDVHLHRPNKSRLMVRLNAVGQPVFLSYFKLLWNTDDQASEKNARETTAEREHQYRSGDELPNKDGSNLKYKMEWNTEGTEALLDEDGDLEVVRRPQSASDSEAEDLMRDRVYPVILMRGKEDAFEDEEQECTCSNVIKIEHTMATPLEDVGKQVWRAAFLLADYILFKRDMFRSCTVLELGGGTGIASIIMGTVANRVYCTDVGEDLLAMCEQNVALNKHLMEPGGGEIKVKELDWLKDEFCTDPEALYSWSEEEIADLHDYCTVIMAADVFYDDDLTDALFRTLYRITHNLKHSCTVFLAIEKRLNFTLRQMDVTCEAYSHFRSTLNDLENLHDGKMKYSVEPVKPDFCQFLIYERIEQLELWKIIADQLT", "length": 393, "header": "tr|A0A8V0Z7S4-1|A0A8V0Z7S4_CHICK Isoform 1 of Methyltransferase-like protein 22 OS=Gallus gallus OX=9031 GN=METTL22 PE=3 SV=1 CANONICAL=A0A8V0Z7S4-1" }, "locus": { "chromosome": "14", "start_pos": 10130721, "end_pos": 10121964, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041893.1", "url": "https://www.ensembl.org/id/ENSGALT00010041893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024505.1", "url": "https://www.ensembl.org/id/ENSGALP00010024505.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425865", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425865", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HDP7-1", "protein_name": "Methyltransferase-like protein 22", "gene_name": "Mettl22", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDEVTFKSDTVLSDVHLYTPNQRHLMVRLNGMGQPVFLSQFKLLWSRDSWTHSGAEDSGPRDVATQETSPAGSESGHSHEDLSLQAGDDITIQERLNVPLDEDGDLDVVRRPRAASDPNPAEPARNKVHPMILAQEEDDLLGDEEQENCPHSIIKIEHTMATPLEDVGKQVWRGALFLADYILFRRDLFQGCTVLELGAGTGLASIVAATMAHTVYCTDVGTDLLTMCQRNVALNSHLAATGDGVIKVKELDWLKDDLCTDPKVPFSWSEEDVRDMYDHTTVLFAAEVFYDDDLTDALFNTLSRLVHRLKNACTAILSVEKRFNFTLRHLDVTCEAYDHFRASLDSLEKLADGRLRFMVEPVEASFPQLLIYERIRQLELWKIRVEPTA", "length": 389 }, "evidence": [ { "id": "A0A8V0Z7S4", "url": "https://omabrowser.org/oma/group/A0A8V0Z7S4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3Z9R2-1", "protein_name": "Methyltransferase-like protein 22", "gene_name": "Mettl22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDSSQYLGHACADSPSWRLPEPYGEGSAWDFRPGSWLVHPRNNMGPAMDEVTFKSDTVLSDVHLYTPNQRHLMVRLNGMGQPVFLSQFKLLWSQDSWTDSGAEDNGPRAVSTEETPPAGSGSGHSHEDLSLQAEDDNTIQEGLSVPLDEDGDLDVVRRPRAASDPNPAEPARDKVHPMILEQEEDDLVGDQARESCPYSIIKIEHTMATPLEDVGKQVWRGALLLADYILFRRDLFQGCTVLELGAGTGLASIVAATMAHTVYCTDVGTDLLAMCQRNVALNRHLAATGGGVVKVKELDWMKDDLCTDPKVPFSWSEEEIADLYDHTTVLLAAEVFYDDDLTNALFHTFSRLVHRLKNACTAILSVEKRFNFTLRHLDVTCEAYDHFRASLDSLEKLADGRLRFLVEPVETSFPQLLGYERIQQLELWKIVVEPAA", "length": 437 }, "evidence": [ { "id": "A0A8V0Z7S4", "url": "https://omabrowser.org/oma/group/A0A8V0Z7S4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R1C6-1", "protein_name": "Methyltransferase-like protein 22", "gene_name": "Mettl22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPAMDEVTFKSDTVLSDVHLYTPNQRHLMVRLNGMGQPVFLSQFKLLWSRDSWTDSGAEDSGPTDVSTEEMPPAGSGSGHSHEDLSLQAGDDNTIQEGLSVPLDEDGDLDVVRRPRAASDPNPAEPARDKVHPTILAQEEDDLVGDQEYESCPHSIIKIEHTMATPLEDVGKQVWRGALLLADYILFRRDLFQGCTVLELGAGTGLASIVAATMAHTVYCTDVGTDLLAMCQRNVALNSHLTATGGGVVKVKELDWLKDNLCTDPKAPFSWSEEEIADLYDHTTVLLAAEVFYDDDLTNALFNTLSRLVHRLKNACTAIFSVEKRFNFTLRHLDVTCEAYDHFRASLDSLEKLADGRLRFMVEPVEASFPQLLVYERIRQLELWKIVVEPAA", "length": 393 }, "evidence": [ { "id": "A0A8V0Z7S4", "url": "https://omabrowser.org/oma/group/A0A8V0Z7S4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BUU2-1", "protein_name": "Methyltransferase-like protein 22", "gene_name": "METTL22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQLAPAAAMDEVTFRSDTVLSDVHLYTPNHRHLMVRLNSVGQPVFLSQFKLLWSQDSWTDSGAKGGSHRDVHTKEPPSAETGSTGSPPGSGHGNEGFSLQAGTDTTGQEVAEAQLDEDGDLDVVRRPRAASDSNPAGPLRDKVHPMILAQEEDDVLGEEAQGSPHDIIRIEHTMATPLEDVGKQVWRGALLLADYILFRQDLFRGCTALELGAGTGLASIIAATMARTVYCTDVGADLLSMCQRNIALNSHLAATGGGIVRVKELDWLKDDLCTDPKVPFSWSQEEISDLYDHTTILFAAEVFYDDDLTDAVFKTLSRLAHRLKNACTAILSVEKRLNFTLRHLDVTCEAYDHFRSCLHALEQLADGKLRFVVEPVEASFPQLLVYERLQQLELWKIIAEPVT", "length": 404 }, "evidence": [ { "id": "A0A8V0Z7S4", "url": "https://omabrowser.org/oma/group/A0A8V0Z7S4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z895-1", "uniprot_ac": "A0A8V0Z895", "uniprot_id": "A0A8V0Z895_CHICK", "mass": { "chemical_mass": 84484.0, "monoisotopic_mass": 84484.0 }, "refseq": { "ac": "XP_040529861", "name": "armadillo-like helical domain-containing protein 4 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529861" }, "gene_names": [ { "name": "ARMH4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ] }, { "name": "ARMH4", "type": "synonym", "evidence": [ { "id": "XP_040529861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529861" } ] } ], "protein_names": [ { "name": "Armadillo like helical domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#names_and_taxonomy" } ] }, { "name": "armadillo-like helical domain-containing protein 4 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_040529861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529861" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040529861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529861" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARMH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895", "locus": { "chromosome": "5", "start_pos": 54963789, "end_pos": 54912346, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017452", "url": "https://www.ensembl.org/id/ENSGALG00010017452" } ] } } ], "crossref": [ { "id": "A0A8V0Z895", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z895", "database": "AlphaFoldDB", "categories": [] }, { "id": "423545", "url": "https://www.ncbi.nlm.nih.gov/gene/423545", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HGPWAGN", "url": "https://omabrowser.org/oma/group/HGPWAGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUE1", "url": "https://www.orthodb.org/?gene=A0A8V0YUE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUF4", "url": "https://www.orthodb.org/?gene=A0A8V0YUF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0V0", "url": "https://www.orthodb.org/?gene=A0A8V0Z0V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1A6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1A6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z895", "url": "https://www.orthodb.org/?gene=A0A8V0Z895", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21585", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21585", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21585:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21585:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15767", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15767", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040529861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529861", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YUE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z895-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEGLTQDVTTIAQEAAAAVTAVTLLPAPAQGTGAASLPQETSGEDTQMLSAPGATHMLTAAGTSTVRTPGVEDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKEGDMSSTNFAHSRASWPGIQPERELQGQRMVFPTKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKQREFNSMQDRVMLLADSSEDEF", "length": 795, "header": "tr|A0A8V0Z895-1|A0A8V0Z895_CHICK Isoform 1 of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#A0A8V0YUE1-1", "sequence": { "sequence": "MHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEGLTQDVTTIAQEAAAAVTAVTLLPAPAQGTGAASLPQETSGEDTQMLSAPGATHMLTAAGTSTVRTPGVEDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKQREFNSMQDRVMLLADSSEDEF", "length": 760, "header": "tr|A0A8V0YUE1-1|A0A8V0Z895_CHICK Computationally mapped isoform of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "locus": { "chromosome": "5", "start_pos": 54959536, "end_pos": 54917603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042137.1", "url": "https://www.ensembl.org/id/ENSGALT00010042137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024677.1", "url": "https://www.ensembl.org/id/ENSGALP00010024677.1" } ] } }, { "isoform_ac": "A0A8V0YUF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#A0A8V0YUF4-1", "sequence": { "sequence": "MHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEGLTQDVTTIAQEAAAAVTAVTLLPAPAQGTGAASLPQETSGEDTQMLSAPGATHMLTAAGTSTVRTPDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKQREFNSMQDRVMLLADSSEDEF", "length": 757, "header": "tr|A0A8V0YUF4-1|A0A8V0Z895_CHICK Computationally mapped isoform of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "locus": { "chromosome": "5", "start_pos": 54959536, "end_pos": 54917603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042155.1", "url": "https://www.ensembl.org/id/ENSGALT00010042155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024692.1", "url": "https://www.ensembl.org/id/ENSGALP00010024692.1" } ] } }, { "isoform_ac": "A0A8V0Z0V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#A0A8V0Z0V0-1", "sequence": { "sequence": "MHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKQREFNSMQDRVMLLADSSEDEF", "length": 690, "header": "tr|A0A8V0Z0V0-1|A0A8V0Z895_CHICK Computationally mapped isoform of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "locus": { "chromosome": "5", "start_pos": 54959536, "end_pos": 54917603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042145.1", "url": "https://www.ensembl.org/id/ENSGALT00010042145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024684.1", "url": "https://www.ensembl.org/id/ENSGALP00010024684.1" } ] } }, { "isoform_ac": "A0A8V0Z1A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#A0A8V0Z1A6-1", "sequence": { "sequence": "MQVGTTMGSCFLDLSALWTSMHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEGLTQDVTTIAQEAAAAVTAVTLLPAPAQGTGAASLPQETSGEDTQMLSAPGATHMLTAAGTSTVRTPGVEDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKREFNSMQDRVMLLADSSEDEF", "length": 779, "header": "tr|A0A8V0Z1A6-1|A0A8V0Z895_CHICK Computationally mapped isoform of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "locus": { "chromosome": "5", "start_pos": 54959536, "end_pos": 54912833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042164.1", "url": "https://www.ensembl.org/id/ENSGALT00010042164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024701.1", "url": "https://www.ensembl.org/id/ENSGALP00010024701.1" } ] } }, { "isoform_ac": "A0A8V0Z895-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895/entry#A0A8V0Z895-1", "sequence": { "sequence": "MHTSSAMSRSIGLNICVATCCILLLSSSPPCLAYPLLKERDMTKAQYDAWAGNGVEDERTNMPNLMNKLSPSEQTLSEEPSGVSAKPSGMPLNEAFTSEREMWPVSPSRTFLGSQGLDVSTTVPGALVAVEEELSPTKSELNENGEFKAMLTTAVTTLSPPVQEEPISVATTEDCEVGQSSASLLANSPSVTAAAEEEIAESSLYLSAAPQPHSEQVPTSQPNTPSLERAIDYLIIPTAQAPSESFEVGMPEANTGSAPRLLASQGATAANHPLVTTEAYLHLGADTGVGQGEQPTAASTAFSLPADSMLSDWDDTKLGSTSQQGSMQHEEVGEDQVATETSQIPLGDMEEEEDDVTRVLPSPASAPPTPGLMKEINCTTPAAVHEEDALVTFTASSDVSLTGDLPDVDIGGLNSLENSNMVTAEEKSILPSQPEAPVMTDITPDLSSTLESSLEGLTQDVTTIAQEAAAAVTAVTLLPAPAQGTGAASLPQETSGEDTQMLSAPGATHMLTAAGTSTVRTPGVEDLTDVVLITGEKAVPSPGGLLATQSGQTEEPSSKMMVLVTPASVASSVRRTALPAVRKISTAVTYGLDRLESEEAEEEEEDEEEEEEEEEEEEDEEDKEIDSMDESMEGDTELPGFTLPGETSQEPIAGLENPAAQLAGVSYQVPDTIEWEQQNQGLVRSWMEKLKDKEGDMSSTNFAHSRASWPGIQPERELQGQRMVFPTKAGYMSGMLVPVGVGIAGALFILGALYSIKIMNRRRRNGSKRHKRKQREFNSMQDRVMLLADSSEDEF", "length": 795, "header": "tr|A0A8V0Z895-1|A0A8V0Z895_CHICK Isoform 1 of Armadillo like helical domain containing 4 OS=Gallus gallus OX=9031 GN=ARMH4 PE=4 SV=1 CANONICAL=A0A8V0Z895-1" }, "locus": { "chromosome": "5", "start_pos": 54959536, "end_pos": 54917603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042133.1", "url": "https://www.ensembl.org/id/ENSGALT00010042133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024673.1", "url": "https://www.ensembl.org/id/ENSGALP00010024673.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ], "pmid": "" }, { "name": "regulation of TORC2 signaling", "id": "GO:1903939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903939", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "TORC2 complex binding", "id": "GO:1904841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z895", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z895" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 369 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 377, "end_pos": 379 }, { "start_pos": 765, "end_pos": 767 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8B1-1", "uniprot_ac": "A0A8V0Z8B1", "uniprot_id": "A0A8V0Z8B1_CHICK", "mass": { "chemical_mass": 32203.0, "monoisotopic_mass": 32203.0 }, "refseq": {}, "gene_names": [ { "name": "ZMAT4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" } ] } ], "protein_names": [ { "name": "Zinc finger matrin-type 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMAT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1", "locus": { "chromosome": "22", "start_pos": 2682592, "end_pos": 2728755, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017457", "url": "https://www.ensembl.org/id/ENSGALG00010017457" } ] } } ], "crossref": [ { "id": "A0A8V0Z8B1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8B1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUE5", "url": "https://www.orthodb.org/?gene=A0A8V0YUE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46144:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YUE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEQLVGTGLSSAHPWRETCDADWVGSANSSVPHLQEDSGLQQGVMCLAATEVEWSHREAEMKSSDIDQELFTESYCRVCSAQLISESQRVAHYESRKHASKVRLYYMLHPIDGGCPAKKLRSENGSDGDSVDKNKCCTLCNMSFTSAVVAESHYQGKIHAKRLKLLLGEPPALKATETLGSLKQPRADRPPAASPPQPRRDSDRYCQLCAAWFNNPVMAQQHYDGKKHKKNAARAELLEQLGKTLDLGELRGLKRSYTCNICNVTLNSIEQYHAHLKGSKHQTNLKNQ", "length": 289, "header": "tr|A0A8V0Z8B1-1|A0A8V0Z8B1_CHICK Isoform 1 of Zinc finger matrin-type 4 OS=Gallus gallus OX=9031 GN=ZMAT4 PE=4 SV=1 CANONICAL=A0A8V0Z8B1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1/entry#A0A8V0YUE5-1", "sequence": { "sequence": "MEVFLFPLPLLLILLTAAFPPSSEMKSSDIDQELFTESYCRVCSAQLISESQRVAHYESRKHASKVRLYYMLHPIDGGCPAKKLRSENGSDGDSVDKNKCCTLCNMSFTSAVVAESHYQGKIHAKRLKLLLGEPPALKATETLGSLKQPRADRPPAASPPQPRRDSDRYCQLCAAWFNNPVMAQQHYDGKKHKKNAARAELLEQLGKTLDLGELRGLKRSYTCNICNVTLNSIEQYHAHLKGSKHQTNLKNQ", "length": 252, "header": "tr|A0A8V0YUE5-1|A0A8V0Z8B1_CHICK Computationally mapped isoform of Zinc finger matrin-type 4 OS=Gallus gallus OX=9031 GN=ZMAT4 PE=4 SV=1 CANONICAL=A0A8V0Z8B1-1" }, "locus": { "chromosome": "22", "start_pos": 2716486, "end_pos": 2685086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042143.1", "url": "https://www.ensembl.org/id/ENSGALT00010042143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024682.1", "url": "https://www.ensembl.org/id/ENSGALP00010024682.1" } ] } }, { "isoform_ac": "A0A8V0Z8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1/entry#A0A8V0Z8B1-1", "sequence": { "sequence": "MPEQLVGTGLSSAHPWRETCDADWVGSANSSVPHLQEDSGLQQGVMCLAATEVEWSHREAEMKSSDIDQELFTESYCRVCSAQLISESQRVAHYESRKHASKVRLYYMLHPIDGGCPAKKLRSENGSDGDSVDKNKCCTLCNMSFTSAVVAESHYQGKIHAKRLKLLLGEPPALKATETLGSLKQPRADRPPAASPPQPRRDSDRYCQLCAAWFNNPVMAQQHYDGKKHKKNAARAELLEQLGKTLDLGELRGLKRSYTCNICNVTLNSIEQYHAHLKGSKHQTNLKNQ", "length": 289, "header": "tr|A0A8V0Z8B1-1|A0A8V0Z8B1_CHICK Isoform 1 of Zinc finger matrin-type 4 OS=Gallus gallus OX=9031 GN=ZMAT4 PE=4 SV=1 CANONICAL=A0A8V0Z8B1-1" }, "locus": { "chromosome": "22", "start_pos": 2728556, "end_pos": 2685086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042150.1", "url": "https://www.ensembl.org/id/ENSGALT00010042150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024688.1", "url": "https://www.ensembl.org/id/ENSGALP00010024688.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B1" }, { "id": "PS50171", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Matrin-type", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 235, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8D3-1", "uniprot_ac": "A0A8V0Z8D3", "uniprot_id": "A0A8V0Z8D3_CHICK", "mass": { "chemical_mass": 45860.0, "monoisotopic_mass": 45860.0 }, "refseq": { "ac": "NP_001403489", "name": "protein phosphatase 1 regulatory subunit 36", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489" }, "gene_names": [ { "name": "PPP1R36", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3" } ] }, { "name": "C14orf50", "type": "synonym", "evidence": [ { "id": "NP_001403489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489" } ] }, { "name": "PPP1R36", "type": "synonym", "evidence": [ { "id": "NP_001403489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 36", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 36", "type": "synonym", "evidence": [ { "id": "NP_001403489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888548.533307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On or before Feb 9, 2023 this sequence version replaced XP_001235694.4, XP_040527956.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001403489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3", "locus": { "chromosome": "5", "start_pos": 52358107, "end_pos": 52383846, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017463", "url": "https://www.ensembl.org/id/ENSGALG00010017463" } ] } } ], "crossref": [ { "id": "A0A8V0Z8D3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "776144", "url": "https://www.ncbi.nlm.nih.gov/gene/776144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUH3", "url": "https://www.orthodb.org/?gene=A0A8V0YUH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8D3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21055:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21055:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001403489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001403489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YUH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQTGTMTSTIKLTSGVWYWKDDTNTLEFASSSPAAEENLKEGKNAHLQEICVKTLKSIFQDECSSALPEKRLAGNEEKIHKLSKWIKHEYVTLDDVKYLAFLLREENEPHRMLPFAAVMGNKTLDEFLMALLFYMSFYLEKIALEKKTQSLILSVIFLENKEMDDVLAKLAVAKIYLAKVYSNLVLERGTAQQSRTPRGKRKTSLQKDRNFFEGFYNFCSYVTWLVFRRKHFQVIREEIGRLLCSDMFNLALRDRHRVSLQDAADQTTDANAVILPCQRQVCAKHPPINSMVHQHSPALSTLLPLPKERAQYRAQSHYCRGRGQQPCSCDNLPDFSELFTTKVGIIGTHCSELNSFLLQSDETTEEEEQDQDQEQREEQGKLRSHSFVLTKDLSLSAL", "length": 399, "header": "tr|A0A8V0Z8D3-1|A0A8V0Z8D3_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 36 OS=Gallus gallus OX=9031 GN=PPP1R36 PE=4 SV=1 CANONICAL=A0A8V0Z8D3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3/entry#A0A8V0YUH3-1", "sequence": { "sequence": "MTPTHLNLQGKRMMFSSKLRGLKVQRLHVSSSPAAEENLKEGKNAHLQEICVKTLKSIFQDECSSALPEKRLAGNEEKIHKLSKWIKHEYVTLDDVKYLAFLLREENEPHRMLPFAAVMGNKTLDEFLMALLFYMSFYLEKIALEKKTQSLILSVIFLENKEMDDVLAKLAVAKIYLAKVYSNLVLERGTAQQSRTPRGKRKTSLQKDRNFFEGFYNFCSYVTWLVFRRKHFQVIREEIGRLLCSDMFNLALRDRHRVSLQDAADQTTDANAVILPCQRQVCAKHPPINSMVHQHSPALSTLLPLPKERAQYRAQSHYCRGRGQQPCSCDNLPDFSELFTTKVGIIGTHCSELNSFLLQSDETTEEEEQDQDQEQREEQGKLRSHSFVLTKDLSLSAL", "length": 398, "header": "tr|A0A8V0YUH3-1|A0A8V0Z8D3_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 36 OS=Gallus gallus OX=9031 GN=PPP1R36 PE=4 SV=1 CANONICAL=A0A8V0Z8D3-1" }, "locus": { "chromosome": "5", "start_pos": 52374325, "end_pos": 52360020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042181.1", "url": "https://www.ensembl.org/id/ENSGALT00010042181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024712.1", "url": "https://www.ensembl.org/id/ENSGALP00010024712.1" } ] } }, { "isoform_ac": "A0A8V0Z8D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3/entry#A0A8V0Z8D3-1", "sequence": { "sequence": "MLQTGTMTSTIKLTSGVWYWKDDTNTLEFASSSPAAEENLKEGKNAHLQEICVKTLKSIFQDECSSALPEKRLAGNEEKIHKLSKWIKHEYVTLDDVKYLAFLLREENEPHRMLPFAAVMGNKTLDEFLMALLFYMSFYLEKIALEKKTQSLILSVIFLENKEMDDVLAKLAVAKIYLAKVYSNLVLERGTAQQSRTPRGKRKTSLQKDRNFFEGFYNFCSYVTWLVFRRKHFQVIREEIGRLLCSDMFNLALRDRHRVSLQDAADQTTDANAVILPCQRQVCAKHPPINSMVHQHSPALSTLLPLPKERAQYRAQSHYCRGRGQQPCSCDNLPDFSELFTTKVGIIGTHCSELNSFLLQSDETTEEEEQDQDQEQREEQGKLRSHSFVLTKDLSLSAL", "length": 399, "header": "tr|A0A8V0Z8D3-1|A0A8V0Z8D3_CHICK Isoform 1 of Protein phosphatase 1 regulatory subunit 36 OS=Gallus gallus OX=9031 GN=PPP1R36 PE=4 SV=1 CANONICAL=A0A8V0Z8D3-1" }, "locus": { "chromosome": "5", "start_pos": 52375627, "end_pos": 52360020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042176.1", "url": "https://www.ensembl.org/id/ENSGALT00010042176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024708.1", "url": "https://www.ensembl.org/id/ENSGALP00010024708.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8I5-1", "uniprot_ac": "A0A8V0Z8I5", "uniprot_id": "A0A8V0Z8I5_CHICK", "mass": { "chemical_mass": 125486.0, "monoisotopic_mass": 125486.0 }, "refseq": {}, "gene_names": [ { "name": "MCF2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ] } ], "protein_names": [ { "name": "MCF.2 cell line derived transforming sequence", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YUJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z102", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z102", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z102-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z102-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCGYGESTAPICAKDISDELMKQFAFLSGGRGKDKAWIITLPDNSRFNDVPEDVISKVLTYLTSVPSQHESDTKFILILDRRLDTWTSVKMTLQRIAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQWLVKNLNRRKEGWIPVHSLQIVVGDCRFRNAKVADAALCNTRKFSSP", "length": 1090, "header": "tr|A0A8V0Z8I5-1|A0A8V0Z8I5_CHICK Isoform 1 of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#A0A8V0YUJ1-1", "sequence": { "sequence": "MAEASPARGVRRPRRDAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQWLVKNLNRRKEGWIPVHSLQIVVGDCRFRNAKVADAALCNTRKFSSP", "length": 1009, "header": "tr|A0A8V0YUJ1-1|A0A8V0Z8I5_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "locus": { "chromosome": "4", "start_pos": 5014851, "end_pos": 4981613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042214.1", "url": "https://www.ensembl.org/id/ENSGALT00010042214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024732.1", "url": "https://www.ensembl.org/id/ENSGALP00010024732.1" } ] } }, { "isoform_ac": "A0A8V0YUK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#A0A8V0YUK5-1", "sequence": { "sequence": "MKQFAFLSGGRGKDKAWIITLPDNSRFNDVPEDVISKVLTYLTSVPSQHESDTKFILILDRRLDTWTSVKMTLQRIAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQWLVKNLNRRKEGWIPVHSLQIVVGDCRFRNAKVADAALCNTRKFSSP", "length": 1069, "header": "tr|A0A8V0YUK5-1|A0A8V0Z8I5_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "locus": { "chromosome": "4", "start_pos": 5020963, "end_pos": 4981613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042230.1", "url": "https://www.ensembl.org/id/ENSGALT00010042230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024747.1", "url": "https://www.ensembl.org/id/ENSGALP00010024747.1" } ] } }, { "isoform_ac": "A0A8V0Z102-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#A0A8V0Z102-1", "sequence": { "sequence": "MKQFAFLSGGRGKDKAWIITLPDNSRFNDVPEDVISKVLTYLTSVPSQHESDTKFILILDRRLDTWTSVKMTLQRIAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQWLVKNLNRRKEGWIPVHSLQIVVGDCRFRNAKVAAQTPCE", "length": 1062, "header": "tr|A0A8V0Z102-1|A0A8V0Z8I5_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "locus": { "chromosome": "4", "start_pos": 5020963, "end_pos": 4985220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042221.1", "url": "https://www.ensembl.org/id/ENSGALT00010042221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024739.1", "url": "https://www.ensembl.org/id/ENSGALP00010024739.1" } ] } }, { "isoform_ac": "A0A8V0Z2R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#A0A8V0Z2R4-1", "sequence": { "sequence": "MALAPAPAGPPPGGTSAGEMERYYCLLRAAALLEAAAAESTAPICAKDISDELMKQFAFLSGGRGKDKAWIITLPDNSRFNDVPEDVISKVLTYLTSVPSQHESDTKFILILDRRLDTWTSVKMTLQRIAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQW", "length": 1076, "header": "tr|A0A8V0Z2R4-1|A0A8V0Z8I5_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "locus": { "chromosome": "4", "start_pos": 5029762, "end_pos": 4986991, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042235.1", "url": "https://www.ensembl.org/id/ENSGALT00010042235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024750.1", "url": "https://www.ensembl.org/id/ENSGALP00010024750.1" } ] } }, { "isoform_ac": "A0A8V0Z8I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5/entry#A0A8V0Z8I5-1", "sequence": { "sequence": "MRCGYGESTAPICAKDISDELMKQFAFLSGGRGKDKAWIITLPDNSRFNDVPEDVISKVLTYLTSVPSQHESDTKFILILDRRLDTWTSVKMTLQRIAASFPGNLHLVMVLRPTGFFQRTFTDIGFRFSQEDFLLKLPVVMLSSVSDLLTYIDEQQLTPEFGGTLEYCHSEWVIFRTAIESFALTVKEIAQMLQSFGTELAETELPEDMYSIERILALRTEKYFQLKEDITAVTKEGKLLLSNLEDPDVGECSQDQHRERPGDWETVNRLLGQLREMETAFDGFWEKHQLKMEQYLQLWKFEQSFQEVKNAIEFLMGQQAKLPDTGDSVSQVKQRLKDLSHFDGMAQDLIGKAQVVILHGHQLAANHHYALNLICQQCNELRHHSDVLSDEIKRKQMRLQKTLDLHTRLQQALQCCDEGAYLLANQQMDKCQSKEGAQKALQDIERFLESSSPYLNYDPQSLQYDFESVLTAELKCQIQSVQVKLENVRSMFENRQSCFKKLLDKHVRPVQLVAPRPENPPRSKSPLFSPKHGVDFNSSLKFSFDLSLPGKKTSRKTPSSRKIEVMHDYQEKRNSLQSFISDSDDNLDILKGHVINELIETERVYVEELFTVLTGYRAEMDNPAMVILMPPVLRNRKDVLFGNMPEIYDFHNKIFLHSLESCLGAPERVGFCFLDRREDFQMYEKYCQNKPRSESLWRQCSESTFFQECQRKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKYSTSCDGVQELQEALVAMLDLLKSVNDSMHQISITGYDGDLSELGKVLMQGSFSVWTGHRKGPTKMKDLARFKPMQRHLFLYEKALVFCKKREDHGDGYDKTSSYSFKHFLKMNAVGITENVKGDHRKFEIWYSGREEVYVVQAQTVDLKMAWLNEIRKILFKQQELIKVEKQQPGSCTDQLHLSSQLSDGKQQRASISSEENDSERTSPVPLDSVLLSPQSKPHRSWPGMSQSLEICEGLEEWSGNQYLSNCSDTEEEEGNQLSPGKYKALADCKRRGSEDLLVKNGDEIQLLHEDGEGQWLVKNLNRRKEGWIPVHSLQIVVGDCRFRNAKVADAALCNTRKFSSP", "length": 1090, "header": "tr|A0A8V0Z8I5-1|A0A8V0Z8I5_CHICK Isoform 1 of MCF.2 cell line derived transforming sequence OS=Gallus gallus OX=9031 GN=MCF2 PE=3 SV=1 CANONICAL=A0A8V0Z8I5-1" }, "locus": { "chromosome": "4", "start_pos": 5025699, "end_pos": 4981613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042240.1", "url": "https://www.ensembl.org/id/ENSGALT00010042240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024753.1", "url": "https://www.ensembl.org/id/ENSGALP00010024753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" }, { "start_pos": 994, "end_pos": 996, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 169, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 590, "end_pos": 770, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 788, "end_pos": 904, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1006, "end_pos": 1067, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 537, "end_pos": 539 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 945, "end_pos": 947 }, { "start_pos": 994, "end_pos": 996 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8J3-1", "uniprot_ac": "A0A8V0Z8J3", "uniprot_id": "A0A8V0Z8J3_CHICK", "mass": { "chemical_mass": 66434.0, "monoisotopic_mass": 66434.0 }, "refseq": { "ac": "XP_040521347", "name": "sodium- and chloride-dependent transporter XTRP3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521347" }, "gene_names": [ { "name": "SLC6A20", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ] }, { "name": "SLC6A20", "type": "synonym", "evidence": [ { "id": "XP_040521347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521347" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3/entry#names_and_taxonomy" } ] }, { "name": "sodium- and chloride-dependent transporter XTRP3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040521347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521347" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040521347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3", "locus": { "chromosome": "2", "start_pos": 42736383, "end_pos": 42720671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017488", "url": "https://www.ensembl.org/id/ENSGALG00010017488" } ] } } ], "crossref": [ { "id": "A0A8V0Z8J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "420699", "url": "https://www.ncbi.nlm.nih.gov/gene/420699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420699", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHNNFER", "url": "https://omabrowser.org/oma/group/YHNNFER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUL9", "url": "https://www.orthodb.org/?gene=A0A8V0YUL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1G7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8J3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040521347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YUL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKARPLWDNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGGFLIPYIIMLIVEGMPLLYLELAVGQRMRKGSIGAWKIISPYLCGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWATCPLNSNRTGYEEECEKTSSTQYFWYRQTLNISPSLETSGTVQWEQALCLILAWLVVYLCILRGTASTGKVVYVTASLPYCVLIIYLIRGLTLHGAVNGLIYMFTPKLEQLSNPKTWISAATQIFFSLGLGFGSLIAFASYNDPSNNCERHAIIVSLINSTTSIFASIVTFSIYGFKATFNYESCINKVILLLMNTFDLEEGSLTADNLSEMKDYLMAAHPQEYAQLSPQLKNCSLEAELDTAVQGTGLAFIVYSEAIKNMEVSQLYSVLYFAMLLMLGIGSMLGNTAAILTPLTDSKAITSRFSKEVISGFVCFINCIIGLIFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYIYGLRRFEKDLQTMIGRKLNWYWKAMWAFASPLLIISLFIFYLSDYILTGTLQYQAWDGTQGQLVTRDYPSYALAVIGLLVASSTMCIPLGALLTFIRKRLKRERVSTVA", "length": 592, "header": "tr|A0A8V0Z8J3-1|A0A8V0Z8J3_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A8V0Z8J3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3/entry#A0A8V0YUL9-1", "sequence": { "sequence": "MQGGFLIPYIIMLIVEGMPLLYLELAVGQRMRKGSIGAWKIISPYLCGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWATCPLNSNRTGYEEECEKTSSTQYFWYRQTLNISPSLETSGTVQWEQALCLILAWLVVYLCILRGTASTGKVVYVTASLPYCVLIIYLIRGLTLHGAVNGLIYMFTPKLEQLSNPKTWISAATQIFFSLGLGFGSLIAFASYNDPSNNCERHAIIVSLINSTTSIFASIVTFSIYGFKATFNYESCINKVILLLMNTFDLEEGSLTADNLSEMKDYLMAAHPQEYAQLSPQLKNCSLEAELDTAVQGTGLAFIVYSEAIKNMEVSQLYSVLYFAMLLMLGIGSMLGNTAAILTPLTDSKAITSRFSKEVISGFVCFINCIIGLIFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYIYGLRRFEKDLQTMIGRKLNWYWKAMWAFASPLLIISLFIFYLSDYILTGTLQYQAWDGTQGQLVTRDYPSYALAVIGLLVASSTMCIPLGALLTFIRKRLKRERVSTVA", "length": 554, "header": "tr|A0A8V0YUL9-1|A0A8V0Z8J3_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A8V0Z8J3-1" }, "locus": { "chromosome": "2", "start_pos": 42735293, "end_pos": 42720779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042254.1", "url": "https://www.ensembl.org/id/ENSGALT00010042254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024762.1", "url": "https://www.ensembl.org/id/ENSGALP00010024762.1" } ] } }, { "isoform_ac": "A0A8V0Z1G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3/entry#A0A8V0Z1G7-1", "sequence": { "sequence": "MEKARPLWDNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGGFLIPYIIMLIVEGMPLLYLELAVGQRMRKGSIGAWKIISPYLCGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWATCPLNSNRTGYEEECEKTSSTQYFWYRQTLNISPSLETSGTVQWEQALCLILAWLVVYLCILRGTASTGKVVYVTASLPYCVLIIYLIRGLTLHGAVNGLIYMFTPKLEQLSNPKTWISAATQIFFSLGLGFGSLIAFASYNDPSNNCERHAIIVSLINSTTSIFASIVTFSIYGFKATFNYESCINKVILLLMNTFDLEEGSLTADNLSEMKDYLMAAHPQEYAQLSPQLKNCSLEAELDTAVQGTGLAFIVYSEAIKNMEVSQLYSVLYFAMLLMLGIGSMLGNTAAILTPLTDSKAITSRFSKEVISGFVCFINCIIGLIFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYIYGLRRFEKDLQTMIGRKLNWNPSIPSVGWHTGAAGDKRLPQLRPGSDRAAGGLIHHVHTPGGTPNFHKEETEEGKSLHCRMNTENWIGKDLTHTTSDRALLEASSNHYL", "length": 592, "header": "tr|A0A8V0Z1G7-1|A0A8V0Z8J3_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A8V0Z8J3-1" }, "locus": { "chromosome": "2", "start_pos": 42735379, "end_pos": 42724254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042253.1", "url": "https://www.ensembl.org/id/ENSGALT00010042253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024761.1", "url": "https://www.ensembl.org/id/ENSGALP00010024761.1" } ] } }, { "isoform_ac": "A0A8V0Z8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3/entry#A0A8V0Z8J3-1", "sequence": { "sequence": "MEKARPLWDNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGGFLIPYIIMLIVEGMPLLYLELAVGQRMRKGSIGAWKIISPYLCGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWATCPLNSNRTGYEEECEKTSSTQYFWYRQTLNISPSLETSGTVQWEQALCLILAWLVVYLCILRGTASTGKVVYVTASLPYCVLIIYLIRGLTLHGAVNGLIYMFTPKLEQLSNPKTWISAATQIFFSLGLGFGSLIAFASYNDPSNNCERHAIIVSLINSTTSIFASIVTFSIYGFKATFNYESCINKVILLLMNTFDLEEGSLTADNLSEMKDYLMAAHPQEYAQLSPQLKNCSLEAELDTAVQGTGLAFIVYSEAIKNMEVSQLYSVLYFAMLLMLGIGSMLGNTAAILTPLTDSKAITSRFSKEVISGFVCFINCIIGLIFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYIYGLRRFEKDLQTMIGRKLNWYWKAMWAFASPLLIISLFIFYLSDYILTGTLQYQAWDGTQGQLVTRDYPSYALAVIGLLVASSTMCIPLGALLTFIRKRLKRERVSTVA", "length": 592, "header": "tr|A0A8V0Z8J3-1|A0A8V0Z8J3_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A20 PE=3 SV=1 CANONICAL=A0A8V0Z8J3-1" }, "locus": { "chromosome": "2", "start_pos": 42735293, "end_pos": 42724254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042255.1", "url": "https://www.ensembl.org/id/ENSGALT00010042255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024763.1", "url": "https://www.ensembl.org/id/ENSGALP00010024763.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420699", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-GGA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MRC0-1", "protein_name": "Transporter", "gene_name": "LOC100760123", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLAIKRRASSGQRPGPDGERAWDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYVIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNGNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLVVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTANNLEEVKDYLASTYPSKYSDVFPHIRNCSLESELNTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLQAMTGRSLNWYWKAMWAFVSPVLIISLFVFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 616 }, "evidence": [ { "id": "A0A8V0Z8J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z8J3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q64093-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3", "gene_name": "Slc6a20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLAIKRRASRGQRPGPDEKRARDMEKARPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNRTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYLASTYPNKYSEVFPHIRNCSLESELNTAVQGTGLAFIVYAEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLRAMTGRPLNWYWKAMWAFVSPLLIIGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSSPVA", "length": 616 }, "evidence": [ { "id": "A0A8V0Z8J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z8J3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VDB9-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3A", "gene_name": "Slc6a20a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKARPQWGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSAPVA", "length": 592 }, "evidence": [ { "id": "A0A8V0Z8J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z8J3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP91-1", "protein_name": "Sodium- and chloride-dependent transporter XTRP3", "gene_name": "SLC6A20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRLKRGDADPVA", "length": 592 }, "evidence": [ { "id": "A0A8V0Z8J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z8J3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "L-proline transmembrane transporter activity", "id": "GO:0015193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "proline:sodium symporter activity", "id": "GO:0005298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-proline import across plasma membrane", "id": "GO:1904271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 199 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 357, "end_pos": 359 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8Y0-1", "uniprot_ac": "A0A8V0Z8Y0", "uniprot_id": "A0A8V0Z8Y0_CHICK", "mass": { "chemical_mass": 182175.0, "monoisotopic_mass": 182175.0 }, "refseq": { "ac": "XP_015147014", "name": "eukaryotic translation initiation factor 4 gamma 1 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147014" }, "gene_names": [ { "name": "EIF4G1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0" } ] }, { "name": "EIF4G1", "type": "synonym", "evidence": [ { "id": "XP_015147014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147014" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4 gamma 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 4 gamma 1 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_015147014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147014" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147014.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147014" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0", "locus": { "chromosome": "9", "start_pos": 15611939, "end_pos": 15594466, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017540", "url": "https://www.ensembl.org/id/ENSGALG00010017540" } ] } } ], "crossref": [ { "id": "cd11559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11559", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1G5", "url": "https://www.orthodb.org/?gene=A0A8V0Z1G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1H4", "url": "https://www.orthodb.org/?gene=A0A8V0Z1H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Y0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-166208", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-450408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YV00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKAPQPTGGAPTAPHPAPSPGLPQSAFPPGQTAPVIFNPTPTSQMNTPSQPRQFPAGPRAIHQQGGFRSLQHFYQNRAQPPASASRVQSNTTARPGPPAHVYPAASQVMMIPSQISYTPSQGAYYIPGQGRSTYVVPTQQYPVQPGAPSFYPGASPTEFGTYAGAYYPAQGVQQFPAGVPTAQVIVSQQPPIPPKRERKTIRIRDPNQGGKDITEEIMSGARTSSTPTPPQAGSGLEPQANGETPHVAVIVRPDDRPKPALVVSKPVSLEPSKSASPSPPPPLIPEVEPVVMSTMTLVPMEPPMEADTKVELGEAPPDLHQTFSAITTVPGAGELPLVPPPDMDTAAVVEEEVAEEVEEVAIPLLEPTLQAPALPEVPSVPAAPLMPAVPPVPAAPSPPLVVPPVPEAPAKPASPSPPPPQEEPCPEPVAQPAAEANGVLEEVPQPLPEAPVCQPVPVPISEPAPVPTPAPTLDSPIAQPEELPLPNGMEGSSKVEASEEQPESDISPISEPEEPVQPGTPASPPAEEEEEESEGPAEAQERSSSLAPAPSQTLEATVQVAVSVPKKKRRMKELNKKEAVGDLLDAFKESQISDSASEVENKPPPSAPARETEDAAPTRPQEESEETWEEKEDKLAPEKGKAGDQKYRYKEEQWKPLNPEEKKRYDREFLLGFQFIFASMQKPEGLPQITDVVLDKPCVPSQANKTPLRALDPIRLSGMNCSPDFTPSFANLGRPVMGNRGLPSGLGPRRSQQTQRKEPRKIIATVSLNEDVKLNKAEKAWKPSSKRASEEEDPENIKTQELLRRVRSILNKLTPQMFQQLMKQVMELSIDTEERLKGVIDLVFEKAISEPNFSVAYANMCRCLMGLKVPTTDKPTVTVNFRKLLLNRCQKEFEKDKDDDEIFEKRQKEMDDASAPEEKARMKDELEEARDKARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVIDLRRNSWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMSKDKRRGPPGPSISGGRSSLVADDGWNTVPISKGNRPIDTSRLTKITKPGLIDSNNQLFAPGGRLSWGKGSSGGSGAKPADSASDSGRPATSTLNRFSALQQSTPAESSESRRVVQRSSSSRDRSEKAGDRGDRESRSEKSSDRLERPDRGERGERNRSAVTKRSFSKETEDRSREREKQSGPEAVRKTASMSEERDRSRETIKQEPAPPAASPKPMLSEEELEKKSKAIIEEYLHINDMKEALQCVQELGSPSLLYVFVRNGIESTLERSTISREHMGVLLCHLVKAGTLSKEQYYKGLREILEIAEDMEIDIPHIWLYLAELITPILQEEGIPMEELFREITKPLVPLGKATTLLVEVLGLLCKGMSQKTAGKLWRDGGLSWKEFLPEDQDINKFVTEQKLEYTMGDNSDTPSCKELTSEELCKQMDKLLKENSNNQRIYDWIEANLSEQQVSSNTFIRALMTSVCHSAITFENPYRVDALVISNRAKLLQKYMRDEQKELQALYALQALVVKLDQPPNLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAEDESDNN", "length": 1647, "header": "tr|A0A8V0Z8Y0-1|A0A8V0Z8Y0_CHICK Isoform 1 of Eukaryotic translation initiation factor 4 gamma 1 OS=Gallus gallus OX=9031 GN=EIF4G1 PE=1 SV=1 CANONICAL=A0A8V0Z8Y0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YV00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0/entry#A0A8V0YV00-1", "sequence": { "sequence": "MNKAPQPTGGAPTAPHPAPSPGLPQSAFPPGQTAPVIFNPTPTSQMNTPSQPRQFPAGPRAIHQQHFYQNRAQPPASASRVQSNTTARPGPPAHVYPAASQVMMIPSQISYTPSQGAYYIPGQGRSTYVVPTQQYPVQPGAPSFYPGASPTEFGTYAGAYYPAQGVQQFPAGVPTAQVIVSQQPPIPPKRERKTIRIRDPNQGGKDITEEIMSGARTSSTPTPPQAGSGLEPQANGETPHVAVIVRPDDRPKPALVVSKPVSLEPSKSASPSPPPPLIPEVEPVVMSTMTLVPMEPPMEADTKVELGEAPPDLHQTFSAITTVPGAGELPLVPPPDMDTAAVVEEEVAEEVEEVAIPLLEPTLQAPALPEVPSVPAAPLMPAVPPVPAAPSPPLVVPPVPEAPAKPASPSPPPPQEEPCPEPVAQPAAEANGVLEEVPQPLPEAPVCQPVPVPISEPAPVPTPAPTLDSPIAQPEELPLPNGMEGSSKVEASEEQPESDISPISEPEEPVQPGTPASPPAEEEEEESEGPAEAQERSSSLAPAPSQTLEATVQVAVSVPKKKRRMKELNKKEAVGDLLDAFKESQISDSASEVENKPPPSAPARETEDAAPTRPQEESEETWEEKEDKLAPEKGKAGDQKYRYKEEQWKPLNPEEKKRYDREFLLGFQFIFASMQKPEGLPQITDVVLDKPCVPSQANKTPLRALDPIRLSGMNCSPDFTPSFANLGRPVMGNRGLPSGLGPRRSQQTQRKEPRKIIATVSLNEDVKLNKAEKAWKPSSKRASEEEDPENIKTQELLRRVRSILNKLTPQMFQQLMKQVMELSIDTEERLKGVIDLVFEKAISEPNFSVAYANMCRCLMGLKVPTTDKPTVTVNFRKLLLNRCQKEFEKDKDDDEIFEKRQKEMDDASAPEEKARMKDELEEARDKARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVIDLRRNSWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMSKDKRRGPPGPSISGGRSSLVADDGWNTVPISKGNRPIDTSRLTKITKPGLIDSNNQLFAPGGRLSWGKGSSGGSGAKPADSASDSGRPATSTLNRFSALQQSTPAESSESRRVVQRSSSSRDRSEKAGDRGDRESRSEKSSDRLERPDRGERGERNRSAVTKRSFSKETEDRSREREKQSGPEAVRKTASMSEERDRSRETIKQEPAPPAASPKPMLSEEELEKKSKAIIEEYLHINDMKEALQCVQELGSPSLLYVFVRNGIESTLERSTISREHMGVLLCHLVKAGTLSKEQYYKGLREILEIAEDMEIDIPHIWLYLAELITPILQEEGIPMEELFREITKPLVPLGKATTLLVEVLGLLCKGMSQKTAGKLWRDGGLSWKEFLPEDQDINKFVTEQKLEYTMGDNSDTPSCKELTSEELCKQMDKLLKENSNNQRIYDWIEANLSEQQVSSNTFIRALMTSVCHSAITFENPYRVDALVISNRAKLLQKYMRDEQKELQALYALQALVVKLDQPPNLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAEDESDNN", "length": 1640, "header": "tr|A0A8V0YV00-1|A0A8V0Z8Y0_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 1 OS=Gallus gallus OX=9031 GN=EIF4G1 PE=1 SV=1 CANONICAL=A0A8V0Z8Y0-1" }, "locus": { "chromosome": "9", "start_pos": 15611691, "end_pos": 15596684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042403.1", "url": "https://www.ensembl.org/id/ENSGALT00010042403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024893.1", "url": "https://www.ensembl.org/id/ENSGALP00010024893.1" } ] } }, { "isoform_ac": "A0A8V0Z1G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0/entry#A0A8V0Z1G5-1", "sequence": { "sequence": "MNKAPQPTGGAPTAPHPAPSPGLPQSAFPPGQTAPVIFNPTPTSQMNTPSQPRQGGFRSLQHFYQNRAQPPASASRVQSNTTARPGPPAHVYPAASQVMMIPSQISYTPSQGAYYIPGQGRSTYVVPTQQYPVQPGAPSFYPGASPTEFGTYAGAYYPAQGVQQFPAGVPTAQVIVSQQPPIPPKRERKTIRIRDPNQGGKDITEEIMSGARTSSTPTPPQAGSGLEPQANGETPHVAVIVRPDDRPKPALVVSKPVSLEPSKSASPSPPPPLIPEVEPVVMSTMTLVPMEPPMEADTKVELGEAPPDLHQTFSAITTVPGAGELPLVPPPDMDTAAVVEEEVAEEVEEVAIPLLEPTLQAPALPEVPSVPAAPLMPAVPPVPAAPSPPLVVPPVPEAPAKPASPSPPPPQEEPCPEPVAQPAAEANGVLEEVPQPLPEAPVCQPVPVPISEPAPVPTPAPTLDSPIAQPEELPLPNGMEGSSKVEASEEQPESDISPISEPEEPVQPGTPASPPAEEEEEESEGPAEAQERSSSLAPAPSQTLEATVQVAVSVPKKKRRMKELNKKEAVGDLLDAFKESQISDSASEVENKPPPSAPARETEDAAPTRPQEESEETWEEKEDKLAPEKGKAGDQKYRYKEEQWKPLNPEEKKRYDREFLLGFQFIFASMQKPEGLPQITDVVLDKPCVPSQANKTPLRALDPIRLSGMNCSPDFTPSFANLGRPVMGNRGLPSGLGPRRSQQTQRKEPRKIIATVSLNEDVKLNKAEKAWKPSSKRASEEEDPENIKTQELLRRVRSILNKLTPQMFQQLMKQVMELSIDTEERLKGVIDLVFEKAISEPNFSVAYANMCRCLMGLKVPTTDKPTVTVNFRKLLLNRCQKEFEKDKDDDEIFEKRQKEMDDASAPEEKARMKDELEEARDKARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVIDLRRNSWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMSKDKRRGPPGPSISGGRSSLVADDGWNTVPISKGNRPIDTSRLTKITKPGLIDSNNQLFAPGGRLSWGKGSSGGSGAKPADSASDSGRPATSTLNRFSALQQSTPAESSESRRVVQRSSSSRDRSEKAGDRGDRESRSEKSSDRLERPDRGERGERNRSAVTKRSFSKETEDRSREREKQSGPEAVRKTASMSEERDRSRETIKQEPAPPAASPKPMLSEEELEKKSKAIIEEYLHINDMKEALQCVQELGSPSLLYVFVRNGIESTLERSTISREHMGVLLCHLVKAGTLSKEQYYKGLREILEIAEDMEIDIPHIWLYLAELITPILQEEGIPMEELFREITKPLVPLGKATTLLVEVLGLLCKGMSQKTAGKLWRDGGLSWKEFLPEDQDINKFVTEQKLEYTMGDNSDTPSCKELTSEELCKQMDKLLKENSNNQRIYDWIEANLSEQQVSSNTFIRALMTSVCHSAITFENPYRVDALVISNRAKLLQKYMRDEQKELQALYALQALVVKLDQPPNLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAEDESDNN", "length": 1636, "header": "tr|A0A8V0Z1G5-1|A0A8V0Z8Y0_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 1 OS=Gallus gallus OX=9031 GN=EIF4G1 PE=1 SV=1 CANONICAL=A0A8V0Z8Y0-1" }, "locus": { "chromosome": "9", "start_pos": 15611691, "end_pos": 15596684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042410.1", "url": "https://www.ensembl.org/id/ENSGALT00010042410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024900.1", "url": "https://www.ensembl.org/id/ENSGALP00010024900.1" } ] } }, { "isoform_ac": "A0A8V0Z1H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0/entry#A0A8V0Z1H4-1", "sequence": { "sequence": "MNKAPQPTGGAPTAPHPAPSPGLPQSAFPPGQTAPVIFNPTPTSQMNTPSQPRQHFYQNRAQPPASASRVQSNTTARPGPPAHVYPAASQVMMIPSQISYTPSQGAYYIPGQGRSTYVVPTQQYPVQPGAPSFYPGASPTEFGTYAGAYYPAQGVQQFPAGVPTAQVIVSQQPPIPPKRERKTIRIRDPNQGGKDITEEIMSGARTSSTPTPPQAGSGLEPQANGETPHVAVIVRPDDRPKPALVVSKPVSLEPSKSASPSPPPPLIPEVEPVVMSTMTLVPMEPPMEADTKVELGEAPPDLHQTFSAITTVPGAGELPLVPPPDMDTAAVVEEEVAEEVEEVAIPLLEPTLQAPALPEVPSVPAAPLMPAVPPVPAAPSPPLVVPPVPEAPAKPASPSPPPPQEEPCPEPVAQPAAEANGVLEEVPQPLPEAPVCQPVPVPISEPAPVPTPAPTLDSPIAQPEELPLPNGMEGSSKVEASEEQPESDISPISEPEEPVQPGTPASPPAEEEEEESEGPAEAQERSSSLAPAPSQTLEATVQVAVSVPKKKRRMKELNKKEAVGDLLDAFKESQISDSASEVENKPPPSAPARETEDAAPTRPQEESEETWEEKEDKLAPEKGKAGDQKYRYKEEQWKPLNPEEKKRYDREFLLGFQFIFASMQKPEGLPQITDVVLDKPCVPSQANKTPLRALDPIRLSGMNCSPDFTPSFANLGRPVMGNRGLPSGLGPRRSQQTQRKEPRKIIATVSLNEDVKLNKAEKAWKPSSKRASEEEDPENIKTQELLRRVRSILNKLTPQMFQQLMKQVMELSIDTEERLKGVIDLVFEKAISEPNFSVAYANMCRCLMGLKVPTTDKPTVTVNFRKLLLNRCQKEFEKDKDDDEIFEKRQKEMDDASAPEEKARMKDELEEARDKARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVIDLRRNSWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMSKDKRRGPPGPSISGGRSSLVADDGWNTVPISKGNRPIDTSRLTKITKPGLIDSNNQLFAPGGRLSWGKGSSGGSGAKPADSASDSGRPATSTLNRFSALQQSTPAESSESRRVVQRSSSSRDRSEKAGDRGDRESRSEKSSDRLERPDRGERGERNRSAVTKRSFSKETEDRSREREKQSGPEAVRKTASMSEERDRSRETIKQEPAPPAASPKPMLSEEELEKKSKAIIEEYLHINDMKEALQCVQELGSPSLLYVFVRNGIESTLERSTISREHMGVLLCHLVKAGTLSKEQYYKGLREILEIAEDMEIDIPHIWLYLAELITPILQEEGIPMEELFREITKPLVPLGKATTLLVEVLGLLCKGMSQKTAGKLWRDGGLSWKEFLPEDQDINKFVTEQKLEYTMGDNSDTPSCKELTSEELCKQMDKLLKENSNNQRIYDWIEANLSEQQVSSNTFIRALMTSVCHSAITFENPYRVDALVISNRAKLLQKYMRDEQKELQALYALQALVVKLDQPPNLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAEDESDNN", "length": 1629, "header": "tr|A0A8V0Z1H4-1|A0A8V0Z8Y0_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 1 OS=Gallus gallus OX=9031 GN=EIF4G1 PE=1 SV=1 CANONICAL=A0A8V0Z8Y0-1" }, "locus": { "chromosome": "9", "start_pos": 15611691, "end_pos": 15596684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042415.1", "url": "https://www.ensembl.org/id/ENSGALT00010042415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024905.1", "url": "https://www.ensembl.org/id/ENSGALP00010024905.1" } ] } }, { "isoform_ac": "A0A8V0Z8Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y0/entry#A0A8V0Z8Y0-1", "sequence": { "sequence": "MNKAPQPTGGAPTAPHPAPSPGLPQSAFPPGQTAPVIFNPTPTSQMNTPSQPRQFPAGPRAIHQQGGFRSLQHFYQNRAQPPASASRVQSNTTARPGPPAHVYPAASQVMMIPSQISYTPSQGAYYIPGQGRSTYVVPTQQYPVQPGAPSFYPGASPTEFGTYAGAYYPAQGVQQFPAGVPTAQVIVSQQPPIPPKRERKTIRIRDPNQGGKDITEEIMSGARTSSTPTPPQAGSGLEPQANGETPHVAVIVRPDDRPKPALVVSKPVSLEPSKSASPSPPPPLIPEVEPVVMSTMTLVPMEPPMEADTKVELGEAPPDLHQTFSAITTVPGAGELPLVPPPDMDTAAVVEEEVAEEVEEVAIPLLEPTLQAPALPEVPSVPAAPLMPAVPPVPAAPSPPLVVPPVPEAPAKPASPSPPPPQEEPCPEPVAQPAAEANGVLEEVPQPLPEAPVCQPVPVPISEPAPVPTPAPTLDSPIAQPEELPLPNGMEGSSKVEASEEQPESDISPISEPEEPVQPGTPASPPAEEEEEESEGPAEAQERSSSLAPAPSQTLEATVQVAVSVPKKKRRMKELNKKEAVGDLLDAFKESQISDSASEVENKPPPSAPARETEDAAPTRPQEESEETWEEKEDKLAPEKGKAGDQKYRYKEEQWKPLNPEEKKRYDREFLLGFQFIFASMQKPEGLPQITDVVLDKPCVPSQANKTPLRALDPIRLSGMNCSPDFTPSFANLGRPVMGNRGLPSGLGPRRSQQTQRKEPRKIIATVSLNEDVKLNKAEKAWKPSSKRASEEEDPENIKTQELLRRVRSILNKLTPQMFQQLMKQVMELSIDTEERLKGVIDLVFEKAISEPNFSVAYANMCRCLMGLKVPTTDKPTVTVNFRKLLLNRCQKEFEKDKDDDEIFEKRQKEMDDASAPEEKARMKDELEEARDKARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVIDLRRNSWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMSKDKRRGPPGPSISGGRSSLVADDGWNTVPISKGNRPIDTSRLTKITKPGLIDSNNQLFAPGGRLSWGKGSSGGSGAKPADSASDSGRPATSTLNRFSALQQSTPAESSESRRVVQRSSSSRDRSEKAGDRGDRESRSEKSSDRLERPDRGERGERNRSAVTKRSFSKETEDRSREREKQSGPEAVRKTASMSEERDRSRETIKQEPAPPAASPKPMLSEEELEKKSKAIIEEYLHINDMKEALQCVQELGSPSLLYVFVRNGIESTLERSTISREHMGVLLCHLVKAGTLSKEQYYKGLREILEIAEDMEIDIPHIWLYLAELITPILQEEGIPMEELFREITKPLVPLGKATTLLVEVLGLLCKGMSQKTAGKLWRDGGLSWKEFLPEDQDINKFVTEQKLEYTMGDNSDTPSCKELTSEELCKQMDKLLKENSNNQRIYDWIEANLSEQQVSSNTFIRALMTSVCHSAITFENPYRVDALVISNRAKLLQKYMRDEQKELQALYALQALVVKLDQPPNLLRMFFDALYDEDVIKEEAFYKWESSKDPAEQQGKGVALKSVTAFFTWLREAEDESDNN", "length": 1647, "header": "tr|A0A8V0Z8Y0-1|A0A8V0Z8Y0_CHICK Isoform 1 of Eukaryotic translation initiation factor 4 gamma 1 OS=Gallus gallus OX=9031 GN=EIF4G1 PE=1 SV=1 CANONICAL=A0A8V0Z8Y0-1" }, "locus": { "chromosome": "9", "start_pos": 15611691, "end_pos": 15596684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042399.1", "url": "https://www.ensembl.org/id/ENSGALT00010042399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024889.1", "url": "https://www.ensembl.org/id/ENSGALP00010024889.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 469, "start_aa": "Thr", "end_pos": 469, "end_aa": "Thr", "residue": 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"categories": [ "Protein Classification" ] }, { "id": "CPPMFAS", "url": "https://omabrowser.org/oma/group/CPPMFAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV81", "url": "https://www.orthodb.org/?gene=A0A8V0YV81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV97", "url": "https://www.orthodb.org/?gene=A0A8V0YV97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1L1", "url": "https://www.orthodb.org/?gene=A0A8V0Z1L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z1M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1N5", "url": "https://www.orthodb.org/?gene=A0A8V0Z1N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3C2", "url": "https://www.orthodb.org/?gene=A0A8V0Z3C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z946", "url": "https://www.orthodb.org/?gene=A0A8V0Z946", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21437:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YV81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z946", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z946-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASFGKLTEYFSLRKSRTELRSERRGRRSGSCCCSVTECRSLDRKLQRPLLGKSRTLPSIPQSPVLSRIPLLDSAAFREAMPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1352, "header": "tr|A0A8V0Z946-1|A0A8V0Z946_CHICK Isoform 1 of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YV81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0YV81-1", "sequence": { "sequence": "MPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSATRHQPDVGRRGGEAGGAADERRLPRRAGRLGRLLLRRGAAGALRTGVRLRGGRAVAA", "length": 1032, "header": "tr|A0A8V0YV81-1|A0A8V0Z946_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14181484, "end_pos": 14092996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042478.1", "url": "https://www.ensembl.org/id/ENSGALT00010042478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024968.1", "url": "https://www.ensembl.org/id/ENSGALP00010024968.1" } ] } }, { "isoform_ac": "A0A8V0YV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0YV97-1", "sequence": { "sequence": "MLRASHGQGSPRECTQGQQHCPVPVLREPPVCRSLDRKLQRPLLGKSRTLPSIPQSPVLSRIPLLDSAAFREAMPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1345, "header": "tr|A0A8V0YV97-1|A0A8V0Z946_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14224682, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042493.1", "url": "https://www.ensembl.org/id/ENSGALT00010042493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024983.1", "url": "https://www.ensembl.org/id/ENSGALP00010024983.1" } ] } }, { "isoform_ac": "A0A8V0Z1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z1L1-1", "sequence": { "sequence": "MTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1107, "header": "tr|A0A8V0Z1L1-1|A0A8V0Z946_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14103214, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042459.1", "url": "https://www.ensembl.org/id/ENSGALT00010042459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024950.1", "url": "https://www.ensembl.org/id/ENSGALP00010024950.1" } ] } }, { "isoform_ac": "A0A8V0Z1M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z1M1-1", "sequence": { "sequence": "MASFGKLTEYFSLRKSRTELRSERRGRRSGSCCCSVTECRSLDRKLQRPLLGKSRTLPSIPQSPVLSRIPLLDSAAFREAMPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1309, "header": "tr|A0A8V0Z1M1-1|A0A8V0Z946_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14189674, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042470.1", "url": "https://www.ensembl.org/id/ENSGALT00010042470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024960.1", "url": "https://www.ensembl.org/id/ENSGALP00010024960.1" } ] } }, { "isoform_ac": "A0A8V0Z1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z1N5-1", "sequence": { "sequence": "MPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSGKGLAPHGSTTPQTPSGQQPLCASPADLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1298, "header": "tr|A0A8V0Z1N5-1|A0A8V0Z946_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14181484, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042484.1", "url": "https://www.ensembl.org/id/ENSGALT00010042484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024975.1", "url": "https://www.ensembl.org/id/ENSGALP00010024975.1" } ] } }, { "isoform_ac": "A0A8V0Z3B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z3B0-1", "sequence": { "sequence": "MEPERAAAAQPGRGRGGGGGGGSWSPWEDQSIAEMSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1206, "header": "tr|A0A8V0Z3B0-1|A0A8V0Z3B0_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14143717, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042461.1", "url": "https://www.ensembl.org/id/ENSGALT00010042461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024951.1", "url": "https://www.ensembl.org/id/ENSGALP00010024951.1" } ] } }, { "isoform_ac": "A0A8V0Z3C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z3C2-1", "sequence": { "sequence": "MGAVGAGDAVLLLGDPPAVPAAAHAVGELLPHRSLDRKLQRPLLGKSRTLPSIPQSPVLSRIPLLDSAAFREAMPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1345, "header": "tr|A0A8V0Z3C2-1|A0A8V0Z3C2_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14196283, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042476.1", "url": "https://www.ensembl.org/id/ENSGALT00010042476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024966.1", "url": "https://www.ensembl.org/id/ENSGALP00010024966.1" } ] } }, { "isoform_ac": "A0A8V0Z946-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946/entry#A0A8V0Z946-1", "sequence": { "sequence": "MASFGKLTEYFSLRKSRTELRSERRGRRSGSCCCSVTECRSLDRKLQRPLLGKSRTLPSIPQSPVLSRIPLLDSAAFREAMPEQKPYQKHSAPDGQKGCTVPSAGDAWRLEDDGMDPPGDAPLQPQLRTAVEDAPFSHFRMRSFYMRKSLSVDNHLGSLGYAVHPAETKAERVRTRLRRQFSLGSADKKDFYQSKSESSLSRFAHRLSVKQKQEKRRKAEYGSAELSAFRPRSLSIEWSSSPKMTQQMRDLQLAQARKPPGPSSPNAAKRLYRNLSGKFRVNYTSFDEGSLAGRGEKEKPRKSYLFQSNAALFEAVELQDLDRVQELLKQYSPEELDLNTPNSEGLLPLDIAIMTNNAPIARALLQAGAKESPHFVSLESRSLHLSTLVREAEQRVNELTAQVVNEAPNADCSEKEKQLKAWEWRFRLYKRMKAGFEHARVPDPPANVHLSVASSSSVQVTFCEPLSVNSAVVTKYKVEWSCSPSFSPLVGEAVVDKLKSLHYTIRGLTSGTAYYVQVSAYNMKGWGPPQASVPPFAIPSNWREYDGRAPRRRGQAEALDHLLGQVKTVHQHCICHEPCKNQPQSRKHSVSRSLKHLFHPGSKFLKTLKRGLYLTAIFYKDDNILVTHEDQIPVVEIDDTYSCLLMQDFLWFTKVSCMWDEILWLRQCVTVSQSSCSCILQTRFKMLLAISQMQGLLGIQDLGQVFFEPIKDKQGNILIVTLKEVKTNQTFESVRWVPICKLQTSRKSVSSPEEPTALDTLLISVQDKLAYHQRSSHALPPGLYLGYLKLCSAVDQIRVLVPEQLPNILCHVKIRSNPNISREEWEWLQKMASMEEPVPVESKNETSPNHLFQELQVAIKELMALVNIPLQEAKDFRLYSQEVLDFGGQVSFLLLLPPSDDVCTAPGQNNPYTPQSGFLTLPLQIFELVHFFTYDREFITQYCQVSALLELESLLSQQSLREAFSDSELSTAKQRHQQVQEYIQQMEEIWREMRWMMDALQHARYKQPSCGLSLNGFLSTSSGTAKEKTRSSSSHLDFLPSPAPSPDSSRKLSSDLHGLSDEEGSSEVFLATDSDYDSSRAQSPKELDLVSVGPECCGRRAARSLRDSAPDVLQSHELQPTPLAPPEPRPPPELYDSDFVLPSRQIELLRVTEKRQAYCVRTSSLDFPKPLCPVARKSCPGSVDSSPTESRAGGHGSQGRPGTVSTHSPERGRTRSAEWTPSSQELPEQPGGKKPGSVTLRVCPQYETGLSKETSVKLHVTSQTSAGEVVKLVVLQMNDVSHGALGGSAAFCYGEEQLEHFGLVFASEEGERWLPDEARPLALQAARPEGRFYVRIKETSPLVLQFGPATTV", "length": 1352, "header": "tr|A0A8V0Z946-1|A0A8V0Z946_CHICK Isoform 1 of Ankyrin repeat and fibronectin type-III domain-containing protein 1-like OS=Gallus gallus OX=9031 GN=ANKFN1L PE=4 SV=1 CANONICAL=A0A8V0Z946-1" }, "locus": { "chromosome": "14", "start_pos": 14189674, "end_pos": 14092884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042464.1", "url": "https://www.ensembl.org/id/ENSGALT00010042464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024954.1", "url": "https://www.ensembl.org/id/ENSGALP00010024954.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z946", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z946", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" } ], "pmid": "" }, { "name": "regulation of establishment of bipolar cell polarity", "id": "GO:0061172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z946", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z946", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 444, "end_pos": 541, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z946" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 1236, "end_pos": 1339, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 819, "end_pos": 821 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA77-1", "uniprot_ac": "A0A8V0ZA77", "uniprot_id": "A0A8V0ZA77_CHICK", "mass": { "chemical_mass": 104728.0, "monoisotopic_mass": 104728.0 }, "refseq": { "ac": "XP_004945263", "name": "guanine nucleotide exchange protein SMCR8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945263" }, "gene_names": [ { "name": "SMCR8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77" } ] }, { "name": "SMCR8", "type": "synonym", "evidence": [ { "id": "XP_004945263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945263" } ] } ], "protein_names": [ { "name": "SMCR8-C9orf72 complex subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide exchange protein SMCR8", "type": "synonym", "evidence": [ { "id": "XP_004945263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945263.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945263" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMCR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77", "locus": { "chromosome": "14", "start_pos": 5107924, "end_pos": 5100633, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017741", "url": "https://www.ensembl.org/id/ENSGALG00010017741" } ] } } ], "crossref": [ { "id": "A0A8V0ZA77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA77", "database": "AlphaFoldDB", "categories": [] }, { "id": "416519", "url": "https://www.ncbi.nlm.nih.gov/gene/416519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416519", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416519", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPVKHWV", "url": "https://omabrowser.org/oma/group/KPVKHWV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWB5", "url": "https://www.orthodb.org/?gene=A0A8V0YWB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA77", "url": "https://www.orthodb.org/?gene=A0A8V0ZA77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31334:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31334:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YWB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISAPDVVAFTREEELGDELYREPPLPEEYSVPLFPFAGHGANPWAKVASSKFSRDFILISEFSEQVGPQPLLTIPDDAKVPGSFDLNYFSLRIMSVDYQASFVGHPPGCAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADEHKIMQQFQELSAEFSKASECLKTGNRKAFASELEKKLKDLDYTRTVLHNETEIQKKANDKGYYTTQAIEKANELASVEKSIIEHQDLLKQIRSYPYRKLKESDFHPYEPECTLDQAGAGSEQDLAASDPAEPGEMHLYSRLPSYTPKLIKAKPAKCFDKKLKTLEELCDIYFFTQTLDQLHHIERTFRGDVCYLLTNQISRALLKQQNITNFLFEDVSFLDEKAPENRDRGCQGLSQDAADRKCSEESSTPKVVISLGSYKSSVECVPIKMEQDMDDPQEPAMTESITFEHQENLDYLDADLKGSISSGESIEVLGTEKSASGLMKSESQASLPISPSPQVGRSKVGSRRTVSEDSIEVLSTCPSESLIPEDFKASYPSAINEEPYVDDEEGGLRFNPRLNPDNTDEQEDVSNQENLAQIDSACCIGKESPNFLEPLPELGQKQCDEDGVVRIPPQPYRQAEQGLHSSFVGSPPCDSASGGLLPHELDSRYPTAGREVSRTSLDECSDSTSYISSAASTCSDRTPSPAHPVCLANERHKKKAGQNALRFIRQYPFAHPAIYSLLSGRTLVVLGEDEAIVKKLVTALSIFVPNCGAYAKPVKHWVTSPLHVVDFQKWKLIGLQRTVSPAGVNVLHALSRYSRYVSILDADSKTLRCPMYKGTLVARLADHRTQIKRGSTYYMHVQSVLTQLCSKAFLYTFCHHLHLPINERESEESVVNRRMNFLKLHLGLANEDIKIVQYLAELLKLQYIQEPGQGVNPLLRFDYVPSFLYKI", "length": 935, "header": "tr|A0A8V0ZA77-1|A0A8V0ZA77_CHICK Isoform 1 of SMCR8-C9orf72 complex subunit OS=Gallus gallus OX=9031 GN=SMCR8 PE=3 SV=1 CANONICAL=A0A8V0ZA77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77/entry#A0A8V0YWB5-1", "sequence": { "sequence": "MISAPDVVAFTREEELGDELYREPPLPEEYSVPLFPFAGHGANPWAKVASSKFSRDFILISEFSEQASFVGHPPGCAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADEHKIMQQFQELSAEFSKASECLKTGNRKAFASELEKKLKDLDYTRTVLHNETEIQKKANDKGYYTTQAIEKANELASVEKSIIEHQDLLKQIRSYPYRKLKESDFHPYEPECTLDQAGAGSEQDLAASDPAEPGEMHLYSRLPSYTPKLIKAKPAKCFDKKLKTLEELCDIYFFTQTLDQLHHIERTFRGDVCYLLTNQISRALLKQQNITNFLFEDVSFLDEKAPENRDRGCQGLSQDAADRKCSEESSTPKVVISLGSYKSSVECVPIKMEQDMDDPQEPAMTESITFEHQENLDYLDADLKGSISSGESIEVLGTEKSASGLMKSESQASLPISPSPQVGRSKVGSRRTVSEDSIEVLSTCPSESLIPEDFKASYPSAINEEPYVDDEEGGLRFNPRLNPDNTDEQEDVSNQENLAQIDSACCIGKESPNFLEPLPELGQKQCDEDGVVRIPPQPYRQAEQGLHSSFVGSPPCDSASGGLLPHELDSRYPTAGREVSRTSLDECSDSTSYISSAASTCSDRTPSPAHPVCLANERHKKKAGQNALRFIRQYPFAHPAIYSLLSGRTLVVLGEDEAIVKKLVTALSIFVPNCGAYAKPVKHWVTSPLHVVDFQKWKLIGLQRTVSPAGVNVLHALSRYSRYVSILDADSKTLRCPMYKGTLVARLADHRTQIKRGSTYYMHVQSVLTQLCSKAFLYTFCHHLHLPINERESEESVVNRRMNFLKLHLGLANEDIKIVQYLAELLKLQYIQEPGQGVNPLLRFDYVPSFLYKI", "length": 901, "header": "tr|A0A8V0YWB5-1|A0A8V0ZA77_CHICK Computationally mapped isoform of SMCR8-C9orf72 complex subunit OS=Gallus gallus OX=9031 GN=SMCR8 PE=3 SV=1 CANONICAL=A0A8V0ZA77-1" }, "locus": { "chromosome": "14", "start_pos": 5105827, "end_pos": 5100832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042886.1", "url": "https://www.ensembl.org/id/ENSGALT00010042886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025376.1", "url": "https://www.ensembl.org/id/ENSGALP00010025376.1" } ] } }, { "isoform_ac": "A0A8V0ZA77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77/entry#A0A8V0ZA77-1", "sequence": { "sequence": "MISAPDVVAFTREEELGDELYREPPLPEEYSVPLFPFAGHGANPWAKVASSKFSRDFILISEFSEQVGPQPLLTIPDDAKVPGSFDLNYFSLRIMSVDYQASFVGHPPGCAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADEHKIMQQFQELSAEFSKASECLKTGNRKAFASELEKKLKDLDYTRTVLHNETEIQKKANDKGYYTTQAIEKANELASVEKSIIEHQDLLKQIRSYPYRKLKESDFHPYEPECTLDQAGAGSEQDLAASDPAEPGEMHLYSRLPSYTPKLIKAKPAKCFDKKLKTLEELCDIYFFTQTLDQLHHIERTFRGDVCYLLTNQISRALLKQQNITNFLFEDVSFLDEKAPENRDRGCQGLSQDAADRKCSEESSTPKVVISLGSYKSSVECVPIKMEQDMDDPQEPAMTESITFEHQENLDYLDADLKGSISSGESIEVLGTEKSASGLMKSESQASLPISPSPQVGRSKVGSRRTVSEDSIEVLSTCPSESLIPEDFKASYPSAINEEPYVDDEEGGLRFNPRLNPDNTDEQEDVSNQENLAQIDSACCIGKESPNFLEPLPELGQKQCDEDGVVRIPPQPYRQAEQGLHSSFVGSPPCDSASGGLLPHELDSRYPTAGREVSRTSLDECSDSTSYISSAASTCSDRTPSPAHPVCLANERHKKKAGQNALRFIRQYPFAHPAIYSLLSGRTLVVLGEDEAIVKKLVTALSIFVPNCGAYAKPVKHWVTSPLHVVDFQKWKLIGLQRTVSPAGVNVLHALSRYSRYVSILDADSKTLRCPMYKGTLVARLADHRTQIKRGSTYYMHVQSVLTQLCSKAFLYTFCHHLHLPINERESEESVVNRRMNFLKLHLGLANEDIKIVQYLAELLKLQYIQEPGQGVNPLLRFDYVPSFLYKI", "length": 935, "header": "tr|A0A8V0ZA77-1|A0A8V0ZA77_CHICK Isoform 1 of SMCR8-C9orf72 complex subunit OS=Gallus gallus OX=9031 GN=SMCR8 PE=3 SV=1 CANONICAL=A0A8V0ZA77-1" }, "locus": { "chromosome": "14", "start_pos": 5105827, "end_pos": 5100832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042882.1", "url": "https://www.ensembl.org/id/ENSGALT00010042882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025372.1", "url": "https://www.ensembl.org/id/ENSGALP00010025372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416519", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416519", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BAX9-1", "protein_name": "SMCR8-C9orf72 complex subunit", "gene_name": "SMCR8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MISAPDVVAFTREDEYEEEPYNEPALPEEYSVPLYPFASQGANPWSRLSGAKFSRDFILISEFSEQVGPQPLLTIPNDSKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTETEVQKKANDKGFYSSQAIEKANELASVEKSIIEHQDLLEQIRSYPRRKLKGSDSSPGETGHTQGQPSQAATPSDPDELAEANHFACRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHVEHMFRGDLCYLLTSQIDRALLKQQRITNFLFEDFVEVDGRAVEEQERTPPKPSQDRPPSRALEECPVPQVLVTMGSYRSSVESVLIKMEQELVEEYREAEAAESSSFDPQENLDYLDLDMKGSVSSGESIEVLGAEKPGSVLSTSDSQASLMVPLSPRVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEESCADDGKGAIRFQAGASPPELGEAEEGSSEDTLLQTDACCIGKESGGLQVPLSAPVSALSDEDEVVSVPPQRYRQKDQSFHVDFAVENASASSQDNSSEGFPAYELDPSHLLASRDGSKTSLDDCSDATSYVSSVASASSDRTPSAHATGPSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDEATVRKLVTALSIFVPNYGRCAKPVKHWVSSPLHITDFQKWKLIGLQRVASPAGAGTLHALSRYSRYTSILDLDRKTLRCPLYRGALLPRLADHRTHIRRGGTYYLHVQSLLTQLCAKAFLFAFCHHLHLPAHDREAMEQAASRQASFLQFNLGLVNEDAKVVRHLAELLRLHYTQEPPSTSQPALRFDYVPSFLYKI", "length": 935 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJR6-1", "protein_name": "SMCR8-C9orf72 complex subunit", "gene_name": "Smcr8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELANVEKSIIEHQDLLRQIRSYPRQKMKKPDLHPGDTEHTQDQADQVCPTSNPEESANADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTETLAQLSHIEHMFRGDLCYLLTSQIDRALRKQQPITNFLFEDFVEVDDRMEKQENVPSQPSHGRLPSKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYKEVEATESSSFDPQENLDYMGMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYADNEGAIHFQASASSPELDETQEGNLENIPSQIDSSCCIGKESEGQLVPLPTPAYTLSDEDGVVSIPPQRYIQKDQGLHMDFGMENTDPSPRDNSCEMFPAYDLDPSCLLASRDISKMSLDNYSDSTSYMGSVASTSSDRIPSAPPAGLSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI", "length": 935 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJE9-1", "protein_name": "SMCR8-C9orf72 complex subunit", "gene_name": "SMCR8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPFASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGNFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELASVEKSIIEHQDLLRQIRSYPHRKLRGSSLCPRESEHIQDPPSQAATTSDPEESADTDHYACRPSYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLRHIEHMFRGDLCYLLTSQIDRALLKQQHITSFLFEDLVEVSDRLAEKQESTVSKPHHYGPPSESPEDCLVPQVLISVGSYKSSVESVLIKMEQDLGDEASREAAVMESSSFDPQENLDYLEMDMKGSVSSGESIEVLGTEKPTSVLSKSESQSSLTVPLSPQVVRSKAVSHRTISGDSIEVLSTCPSEALIPDDFKASYPSAINEEESYAEGSQGAIHFQAGISPPEAGEAEEGSSGLALLQTDASCCIGREAGALLVPLSTPGHTLSDEDGVVSVPPQRYRQKDQGFHVDFSVENASPSSRDNSCEGFPAYELDPSHLLTSLDGSKTSLDDHSDATSYGSSVASTSSDRTPSSMPPAGPSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEEEAMVRKLVTALSIFVPGYGRHGKPVKHWLSSPLHITDFQKWKLIGLQRVASPASASALHALSRYSRYTSILDLDRKTLRCPLYRGTLVPRLADHRTHIRRGSTYFLHVQSMLAQLCAKAFLYTFCHHLHLPAHGGEAPELAASRQASFLQLTLGLVHEDVKVVRYLAELLRLHYTQERRGTSQPALRFDYVPSFLYKI", "length": 938 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FA21-1", "protein_name": "Guanine nucleotide exchange protein smcr8a", "gene_name": "smcr8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIGSPDVVAFTKEDDFGDSFSDPLSLPDEFSVPLFTHAANANPWTKTSYAKFSKDFILISEFSEQVGPQPLLTIPSDPKVCGTFDLNYFSLRIMSVDYQASFVGHPPGSNYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADERKIMQQFQELSSEFSKASECLKSGNRKAFANELEKKLKDLEYTRSVLHKETELQKMNNGCYSTQAIEKANELANVEKSIYEHKDLLRQITSYPSRRKRDVDFVQCEAEKPPVMDETLKDTNPSDSAENTVETESRKSSYTPQLIKAKSAKCFDKRLKTLEELCDTSFFLQTLEQLNAVEKSFRGDLCFIYTSQIDRALVSKQRVTSFLFEAEHDWEDGGASKNFSIPSNNPTIPILNFSGEPLSLDSYTTCIDVDHLKPGVESGEGPPESSTSDITQETSEAADTETKGSFSSDKSIEALGSVSPSSLQTNFFDGLERRSKISIPSYSDNASSSIAVPHRRSDGNLVQMDAACCIGQDGFIFEDPLPELAQECCGDTVVNQEPLSLLHGDPALQMDYILEESPNMGLTFSELNTSVLSEEVAKINIEDVFDRTSFMSISTSSDRAVSPFTYGSALTVKQKKKAGHSALRFIRQYPFAQQAISCLLSGRTLVILGVDEGTVRKLVNALFIFVPNLGKYGETVQPWLSTPFQLTDLQRWKLIGLQRAVSPAGSSILHSLNRYSRYISILDCDNKTLRCPPYKGTLISHLADHRTQIKRGSTYFLHIQGMLTQLTAKAFLYTFCHHIHLPMDINDQGSVTSRRTNFLLQLGYTVEESKIIQYLSELIKQHYIHGSAKVGNPSFSFNYTTSYLYKI", "length": 853 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UMB5-1", "protein_name": "Guanine nucleotide exchange protein SMCR8", "gene_name": "Smcr8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKMGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELANVEKSIIEHQDLLRQIRSYPRQKTKIPDLQPGDTEHTQDQADQVSTTSNPEESANADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRVLRKQQPITNFLFEDFVEVDDRMEKQENVPSQPSQDRLPPKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYTGVEATEARSFDPQENLDYLDMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYADNEGAIHFQASAGSPEPDETQEGNLENIPSQIDSSCCIGKESEGHLVPLPTPAYTLSDEDSVVSIPPQRYIQKDQGLHVDFGVENTDPSPRDNSCEMFPAYELDPSCLLASRDVSKMSLDNYSDTTSYMGSAASTSSDRIPSAPPAGLSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI", "length": 935 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TEV9-1", "protein_name": "Guanine nucleotide exchange protein SMCR8", "gene_name": "SMCR8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISAPDVVAFTKEEEYEEEPYNEPALPEEYSVPLFPFASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSRASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTETEIQKKANDKGFYSSQAIEKANELASVEKSIIEHQDLLKQIRSYPHRKLKGHDLCPGEMEHIQDQASQASTTSNPDESADTDLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRALLKQQHITNFLFEDFVEVDDRMVEKQESIPSKPSQDRPPSSSLEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYKEVEVTELSSFDPQENLDYLDMDMKGSISSGESIEVLGTEKSTSVLSKSDSQASLTVPLSPQVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEESYPDGNEGAIRFQASISPPELGETEEGSIENTPSQIDSSCCIGKESDGQLVLPSTPAHTHSDEDGVVSSPPQRHRQKDQGFRVDFSVENANPSSRDNSCEGFPAYELDPSHLLASRDISKTSLDNYSDTTSYVSSVASTSSDRIPSAYPAGLSSDRHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDEAIVRKLVTALAIFVPSYGCYAKPVKHWASSPLHIMDFQKWKLIGLQRVASPAGAGTLHALSRYSRYTSILDLDNKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPTHDKETEELVASRQMSFLKLTLGLVNEDVRVVQYLAELLKLHYMQESPGTSHPMLRFDYVPSFLYKI", "length": 937 }, "evidence": [ { "id": "A0A8V0ZA77", "url": "https://omabrowser.org/oma/group/A0A8V0ZA77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA77" } ], "pmid": "" }, { "name": "protein 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}, { "id": "A0A8V0Z4Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z500", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z500", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z500-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z500-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KSRNPLDFSMQGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 348, "header": "tr|A0A8V0ZAT1-1|A0A8V0ZAT1_CHICK Isoform 1 of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YX00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0YX00-1", "sequence": { "sequence": "MGCILSAALQAPFLAAWSQQECWSSALLWMYLAMGSIDPDLSLTTWLDLSAPMKVLWAASCSASSLRKGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 405, "header": "tr|A0A8V0YX00-1|A0A8V0ZAT1_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11507198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043123.1", "url": "https://www.ensembl.org/id/ENSGALT00010043123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025608.1", "url": "https://www.ensembl.org/id/ENSGALP00010025608.1" } ] } }, { "isoform_ac": "A0A8V0Z3C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z3C1-1", "sequence": { "sequence": "MQGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 339, "header": "tr|A0A8V0Z3C1-1|A0A8V0Z3C1_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11518324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043100.1", "url": "https://www.ensembl.org/id/ENSGALT00010043100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025590.1", "url": "https://www.ensembl.org/id/ENSGALP00010025590.1" } ] } }, { "isoform_ac": "A0A8V0Z3C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z3C3-1", "sequence": { "sequence": "MFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 335, "header": "tr|A0A8V0Z3C3-1|A0A8V0Z3C3_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11518336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043105.1", "url": "https://www.ensembl.org/id/ENSGALT00010043105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025595.1", "url": "https://www.ensembl.org/id/ENSGALP00010025595.1" } ] } }, { "isoform_ac": "A0A8V0Z3D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z3D3-1", "sequence": { "sequence": "MKCALRSEQEQDALFMTVNTQYLDSKVTQTALGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 369, "header": "tr|A0A8V0Z3D3-1|A0A8V0Z3D3_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11511512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043119.1", "url": "https://www.ensembl.org/id/ENSGALT00010043119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025605.1", "url": "https://www.ensembl.org/id/ENSGALP00010025605.1" } ] } }, { "isoform_ac": "A0A8V0Z3V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z3V4-1", "sequence": { "sequence": "MLCAGPSCLGNILVKSIWCFQSTLCNLSMQGMPSALTFQYYYLCRSFHFPASALILLHSSARIKYMKCALRSEQEQDALFMTVNTQYLDSKVTQTALGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 434, "header": "tr|A0A8V0Z3V4-1|A0A8V0Z3V4_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11511317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043108.1", "url": "https://www.ensembl.org/id/ENSGALT00010043108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025597.1", "url": "https://www.ensembl.org/id/ENSGALP00010025597.1" } ] } }, { "isoform_ac": "A0A8V0Z3W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z3W7-1", "sequence": { "sequence": "MGCILSAALQAPFLAAWSQQGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 357, "header": "tr|A0A8V0Z3W7-1|A0A8V0Z3W7_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11507198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043129.1", "url": "https://www.ensembl.org/id/ENSGALT00010043129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025612.1", "url": "https://www.ensembl.org/id/ENSGALP00010025612.1" } ] } }, { "isoform_ac": "A0A8V0Z4Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z4Z6-1", "sequence": { "sequence": "MHNSLVGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 343, "header": "tr|A0A8V0Z4Z6-1|A0A8V0Z4Z6_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11510696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043115.1", "url": "https://www.ensembl.org/id/ENSGALT00010043115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025601.1", "url": "https://www.ensembl.org/id/ENSGALP00010025601.1" } ] } }, { "isoform_ac": "A0A8V0Z500-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0Z500-1", "sequence": { "sequence": "MQECWSSALLWMYLAMGSIDPDLSLTTWLDLSAPMKVLWAASCSASSLRKFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 335, "header": "tr|A0A8V0Z500-1|A0A8V0Z500_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11510473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043120.1", "url": "https://www.ensembl.org/id/ENSGALT00010043120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025606.1", "url": "https://www.ensembl.org/id/ENSGALP00010025606.1" } ] } }, { "isoform_ac": "A0A8V0ZAT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0ZAT1-1", "sequence": { "sequence": "KSRNPLDFSMQGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 348, "header": "tr|A0A8V0ZAT1-1|A0A8V0ZAT1_CHICK Isoform 1 of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11517473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043099.1", "url": "https://www.ensembl.org/id/ENSGALT00010043099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025589.1", "url": "https://www.ensembl.org/id/ENSGALP00010025589.1" } ] } }, { "isoform_ac": "A0A8V0ZAU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1/entry#A0A8V0ZAU1-1", "sequence": { "sequence": "MYLAMGSIDPDLSLTTWLDLSAPMKVLWAASCSASSLRKGSMFNTWKPMWVVLLEDGIEFYKRKSDNSPKGMIPLKGSTINSPCQDFGKRMFVFKLTAAKQQDHFFQASYLEERDAWVRDIKKAIQCIDGGQRFARKSTRKSIRLPETINLSALYLSMKDPEKGIKELKLEKDKKVFNHCFTGTAVIDWLVSSNSIRNRKEGLMLASSLLNEGYLQPAGDTSKAAAEGLSDTPFLDLSDAYYYFPDSGFFCEGNSSDDDVVLKEEFRGMIVKQGCLLKQGHRRKNWKVRKFVLREDPAYLHYYDPAGGEDPLGAIHLRGCVVTAVEDMPDSKKYDVENNLFEIITASEVHYYLQAASSAERTEWIKAIQSVARTGK", "length": 376, "header": "tr|A0A8V0ZAU1-1|A0A8V0ZAU1_CHICK Computationally mapped isoform of Pleckstrin OS=Gallus gallus OX=9031 GN=PLEK PE=1 SV=1 CANONICAL=A0A8V0ZAT1-1" }, "locus": { "chromosome": "3", "start_pos": 11529648, "end_pos": 11510506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043112.1", "url": "https://www.ensembl.org/id/ENSGALT00010043112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025599.1", "url": "https://www.ensembl.org/id/ENSGALP00010025599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MRZ8-1", "protein_name": "Pleckstrin", "gene_name": "PLEK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPKRIREGYLVKKGSMFNSWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSALTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKATKCIEGGQKFARKSTRRSIRLPETIDLSALYLSMKDTEKGVKELNLEKDKKIFNHCFTGNCVIDWLVSNKSVRNRQEGLVIASSLLNEGYLQPAGDLSKNAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIRLRGCVVTSVESHPDGKKSEEENLFEIITADEVHYFLQAATPKERIEWIKAIQVASRTGK", "length": 350 }, "evidence": [ { "id": "A0A8V0ZAT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SJ07-1", "protein_name": "Pleckstrin", "gene_name": "PLEK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPKRIREGYLVKKGSMFNTWKPMWVILLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDGWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDTEKGIKELNLEKDKKVFNHCFTGNCVIDWLLSNNSVRNRQEGIMIASSLLNEGYLQPAGDLSKSAVDGTAENPFLDNADAFYYFPDSGFFCEDNSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIHLRGCVVTSVESNTDGRRSEEENLFEIITADEVHYFLQAANPKERTEWIKAIQVASRTGK", "length": 350 }, "evidence": [ { "id": "A0A8V0ZAT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08567-1", "protein_name": "Pleckstrin", "gene_name": "PLEK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDTEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNQSVRNRQEGLMIASSLLNEGYLQPAGDMSKSAVDGTAENPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGAEDPLGAIHLRGCVVTSVESNSNGRKSEEENLFEIITADEVHYFLQAATPKERTEWIRAIQMASRTGK", "length": 350 }, "evidence": [ { "id": "A0A8V0ZAT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4KM33-1", "protein_name": "Pleckstrin", "gene_name": "Plek", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNNPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAYLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCFTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPASDLSKNAADGIAENPFLDNPDAFYYFPDSGFFCEENSSDDDIILKEEFRGIIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAIHLRGCVVTSVESNPDGKKSDEENLFEIITADEVHYYMQAATAKERTEWIKAIQVASRTGK", "length": 350 }, "evidence": [ { "id": "A0A8V0ZAT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHK5-1", "protein_name": "Pleckstrin", "gene_name": "Plek", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCLTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPAGDLSKNAADGIAENPFLDSPDAFYYFPDSGFFCEENSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAIQVASRTGK", "length": 350 }, "evidence": [ { "id": "A0A8V0ZAT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 22, "go_terms": [ { "name": "platelet degranulation", "id": "GO:0002576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT1" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420761", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420761", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKMVGEX", "url": "https://omabrowser.org/oma/group/VKMVGEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXN5", "url": "https://www.orthodb.org/?gene=A0A8V0YXN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z401", "url": "https://www.orthodb.org/?gene=A0A8V0Z401", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4F9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4G9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4H4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5J5", "url": "https://www.orthodb.org/?gene=A0A8V0Z5J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZBF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YXN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z401", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z401", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z401-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z401-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPPDSSKSLSLCNLIMEEIPNSGSSEDVNRSQTDLGSLNWGLDVSTPSVSQEITTGGSLLFPGAEQTSSESMGILPPSVWPTVGQQEDAAPGSASENENQRTSLEDLLDAKKIPWEDVTTSQRLENITGFETPFLGTDSLLDKPLSCDVQKEEEKHEEEESLWAGVKPSEKASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 851, "header": "tr|A0A8V0ZBF8-1|A0A8V0ZBF8_CHICK Isoform 1 of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0YXN5-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGETRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 650, "header": "tr|A0A8V0YXN5-1|A0A8V0ZBF8_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043444.1", "url": "https://www.ensembl.org/id/ENSGALT00010043444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025824.1", "url": "https://www.ensembl.org/id/ENSGALP00010025824.1" } ] } }, { "isoform_ac": "A0A8V0Z401-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0Z401-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 674, "header": "tr|A0A8V0Z401-1|A0A8V0Z401_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043447.1", "url": "https://www.ensembl.org/id/ENSGALT00010043447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025826.1", "url": "https://www.ensembl.org/id/ENSGALP00010025826.1" } ] } }, { "isoform_ac": "A0A8V0Z4F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0Z4F9-1", "sequence": { "sequence": "MNLVFSHQVRLYLFHLVFFLCFSVCLKPDSSKSLSLCNLIMEEIPNSGSSEDVNRSQTDLGSLNWGLDVSTPSVSQEITTGGSLLFPGAEQTSSESMGILPPSVWPTVGQQEDAAPGSASENENQRTSLEDLLDAKKIPWEDVTTSQRLENITGFETPFLGTDSLLDKPLSCDVQKEEEKHEEEESLWAGVKPSEKVENGAVNYKEIESTEEMEKQGGEMEGNSEAELHKCLAKSECETSVSTEVDNLHELEVSNGEAGRASVANLEIPREKEFKGVNVTEETDSKKPLLSTGLEDGNKVVVDSCKTTKSIGNEPERVFGIWNQDHETILEDDLNQADNVTGQNLSTEGINVMVTDHAEKNHTNTENIICDAELFNAEESGKEAEDGSISILPNGSANNESQAADDKERPQEWALIPETPHAASTMCRNPCLDNEEDQMTGRAAAAATEEHPHSSGVSETLETDPWLANWDPTVTNDSWGFSNMSDGQANGLDNWPFFPKQQDSEEGNMENAWSGISDKWSTQDLGGTDNIWGEVSVSTSNKNQEEPIKQGLPGKQESVSNTGLSNETVRPLALFQMGNSRNASTESSTSPKDNETNNSDLSEDEIANRRYGLLYQEIEADKEEASSTAFNGFAQDTAAFAVQSNENVTETLVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 857, "header": "tr|A0A8V0Z4F9-1|A0A8V0Z4F9_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49169807, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043421.1", "url": "https://www.ensembl.org/id/ENSGALT00010043421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025808.1", "url": "https://www.ensembl.org/id/ENSGALP00010025808.1" } ] } }, { "isoform_ac": "A0A8V0Z4G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0Z4G9-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPASSTAFNGFAQDTAAFAVQSNENVTETLESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 643, "header": "tr|A0A8V0Z4G9-1|A0A8V0Z4G9_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043435.1", "url": "https://www.ensembl.org/id/ENSGALT00010043435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025818.1", "url": "https://www.ensembl.org/id/ENSGALP00010025818.1" } ] } }, { "isoform_ac": "A0A8V0Z4H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0Z4H4-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 682, "header": "tr|A0A8V0Z4H4-1|A0A8V0Z4H4_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043442.1", "url": "https://www.ensembl.org/id/ENSGALT00010043442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025823.1", "url": "https://www.ensembl.org/id/ENSGALP00010025823.1" } ] } }, { "isoform_ac": "A0A8V0Z5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0Z5J5-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQVFLDTSHDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 662, "header": "tr|A0A8V0Z5J5-1|A0A8V0ZBF8_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043427.1", "url": "https://www.ensembl.org/id/ENSGALT00010043427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025812.1", "url": "https://www.ensembl.org/id/ENSGALP00010025812.1" } ] } }, { "isoform_ac": "A0A8V0ZBF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0ZBF2-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQTLPWDLWTTTSELVQPASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 646, "header": "tr|A0A8V0ZBF2-1|A0A8V0ZBF2_CHICK Computationally mapped isoform of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043432.1", "url": "https://www.ensembl.org/id/ENSGALT00010043432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025815.1", "url": "https://www.ensembl.org/id/ENSGALP00010025815.1" } ] } }, { "isoform_ac": "A0A8V0ZBF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8/entry#A0A8V0ZBF8-1", "sequence": { "sequence": "MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLCIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPPDSSKSLSLCNLIMEEIPNSGSSEDVNRSQTDLGSLNWGLDVSTPSVSQEITTGGSLLFPGAEQTSSESMGILPPSVWPTVGQQEDAAPGSASENENQRTSLEDLLDAKKIPWEDVTTSQRLENITGFETPFLGTDSLLDKPLSCDVQKEEEKHEEEESLWAGVKPSEKASSTAFNGFAQDTAAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEVIPAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQTGSEQKATEEIQTTPSQDQPVSAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE", "length": 851, "header": "tr|A0A8V0ZBF8-1|A0A8V0ZBF8_CHICK Isoform 1 of Amphiphysin OS=Gallus gallus OX=9031 GN=AMPH PE=4 SV=1 CANONICAL=A0A8V0ZBF8-1" }, "locus": { "chromosome": "2", "start_pos": 49251454, "end_pos": 49146824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043438.1", "url": "https://www.ensembl.org/id/ENSGALT00010043438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025820.1", "url": "https://www.ensembl.org/id/ENSGALP00010025820.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 274, "start_aa": "Thr", "end_pos": 274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr274", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 606, "start_aa": "Thr", "end_pos": 606, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr606", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420761", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420761", "resource": "KEGG Pathway" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L8X6-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPIPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIINFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPDVASAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTIQTDQSMICNLAESEQAPPTEPKAEELPAAVPSAPGLDLGLDTRAEEPVEGAAIIPGTDVDVTAGTFVPAAEGAPVEEVETDKVALSAGEEASLEEAKIDAEATEAVESDISQPEETEVVAVQEKVIPSVVIEPASNNEGEGEHEVTPGAEYKEITDDVALPGPASETPELASQPAPSAPSTGLASQEVPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD", "length": 678 }, "evidence": [ { "id": "A0A8V0ZBF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O08838-1", "protein_name": "Amphiphysin", "gene_name": "Amph", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFSIQGAPSDSGPLRIAKTPSPPEEASPLPSPTASPNHTLAPASPAPVRPRSPSQTRKGPPVPPLPKVTPTKELQQENIINFFEDNFVPEINVTTPSQNEVLEVKKEETLLDLDFDPFKPDVTPAGSAAATHSPMSQTLPWDLWTTSTDLVQPASGGSFNDFTQPQDTSLFTMQTDQNMAETEQALPTEPQAEEPPTTAAAPTAGLDLGLEMEEPKEEAAIPPGTDAGETVGTEGSTGEEAEAEKAALPAGEGESPEGAKIDVESTELASSESPQAAELEAGAPQEKVIPSVVIEPASNHEGEEHQETTTGTETREATEDVAPQGPAGEKQELATEPTPLDSQAATPAPAGAVDASLSAGDAAQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRHLE", "length": 683 }, "evidence": [ { "id": "A0A8V0ZBF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD", "length": 695 }, "evidence": [ { "id": "A0A8V0ZBF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQF7-1", "protein_name": "Amphiphysin", "gene_name": "Amph", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSSRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFSIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPVRPRSPSQTRKGPPVPPLPKVTPTKELKQENIINFFEDNFVPEINVTTPSQNEVLEVKKEETLLDLDFDPFKPDVAPAGSAAATHSPMSQTLPWDLWTTSTDLVQPASGGSFNDFTQAQDTSLFTMQTDQNMAETEQALPTEPQAEEPPATAAAPTAGLDLGLEMEEPKEEAVIPPATDTGETVETAVPTEGAPVEEAEAEKAALPAGEGGSPEGAKIDGESTELAISESPQPVEPEAGAPQVIPSVVIEPASNHEGEGEHQETATGTEPREAAEDVAAQGSAGEKQEVATEPTPLDSQATLPASAGAVDASLSAGDATQELPPGFLYKVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLE", "length": 686 }, "evidence": [ { "id": "A0A8V0ZBF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" }, { "id": "PS51021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAR", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 240, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF8" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 778, "end_pos": 851, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 274, 471, 606 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 845, "end_pos": 847 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7T8-1", "uniprot_ac": "A0A8V0Z7T8", "uniprot_id": "A0A8V0Z7T8_CHICK", "mass": { "chemical_mass": 25633.0, "monoisotopic_mass": 25633.0 }, "refseq": {}, "gene_names": [ { "name": "CD8BP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ] } ], "protein_names": [ { "name": "CD8b molecule pseudo", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD8BP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8", "locus": { "chromosome": "4", "start_pos": 85539250, "end_pos": 85554156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017365", "url": "https://www.ensembl.org/id/ENSGALG00010017365" } ] } } ], "crossref": [ { "id": "A0A8V0Z7T8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396175", "url": "https://www.ncbi.nlm.nih.gov/gene/396175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396175", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396175", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLWLRIH", "url": "https://omabrowser.org/oma/group/RLWLRIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0D5", "url": "https://www.orthodb.org/?gene=A0A8V0Z0D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z241", "url": "https://www.orthodb.org/?gene=A0A8V0Z241", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7T8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11292:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11292:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z241", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z241", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z241-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z241-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLDMATMARPWLWLWLCLQLPGFCTNLLSSQTPGYILTKTNNSTEIVCPMKGEHTGVYWYRWNQGRQHFEFLLFSSPLGKATYGTNISQEKFSIRGTSSYHSYRLHINRLHGSDNGTYYCCTIQSSQLILGTGTQLDVVDVLPLPSMPTLVPLTKKPMRCKPKNKAINKKGACTPMVWVPLAAGALLLLLSLIPTIRRFYRLRRRLWVRAHRRFPSNQAGMDH", "length": 224, "header": "tr|A0A8V0Z7T8-1|A0A8V0Z7T8_CHICK Isoform 1 of CD8b molecule pseudo OS=Gallus gallus OX=9031 GN=CD8BP PE=4 SV=1 CANONICAL=A0A8V0Z7T8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8/entry#A0A8V0Z0D5-1", "sequence": { "sequence": "MMLDMATMARPWLWLWLCLQLPGFCTNLLSSQTPGYILTKTNNSTEIVCPMKGEHTGVYWYRWNQGRQHFEFLLFSSPLGKATYGTNISQEKFSIRGTSSYHSYRLHINRLHGSDNGTYYCCTIQSSQLILGTGTQLDVVDVLPLPSMPTLVPLTKKPMRCKPKNKAINKKGACTPMVWVPLAAGALLLLLSLIPTIRRFYRLRRRLWVRAHRR", "length": 214, "header": "tr|A0A8V0Z0D5-1|A0A8V0Z7T8_CHICK Computationally mapped isoform of CD8b molecule pseudo OS=Gallus gallus OX=9031 GN=CD8BP PE=4 SV=1 CANONICAL=A0A8V0Z7T8-1" }, "locus": { "chromosome": "4", "start_pos": 85553722, "end_pos": 85549317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041903.1", "url": "https://www.ensembl.org/id/ENSGALT00010041903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024512.1", "url": "https://www.ensembl.org/id/ENSGALP00010024512.1" } ] } }, { "isoform_ac": "A0A8V0Z241-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8/entry#A0A8V0Z241-1", "sequence": { "sequence": "MGQWWHPVGKIHSSVFLPLFVGFCTNLLSSQTPGYILTKTNNSTEIVCPMKGEHTGVYWYRWNQGRQHFEFLLFSSPLGKATYGTNISQEKFSIRGTSSYHSYRLHINRLHGSDNGTYYCCTIQSSQLILGTGTQLDVVDVLPLPSMPTLVPLTKKPMRCKPKNKAINKKGACTPMVWVPLAAGALLLLLSLIPTIRRFYRLRRRLWVRAHRR", "length": 213, "header": "tr|A0A8V0Z241-1|A0A8V0Z7T8_CHICK Computationally mapped isoform of CD8b molecule pseudo OS=Gallus gallus OX=9031 GN=CD8BP PE=4 SV=1 CANONICAL=A0A8V0Z7T8-1" }, "locus": { "chromosome": "4", "start_pos": 85551747, "end_pos": 85549317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041895.1", "url": "https://www.ensembl.org/id/ENSGALT00010041895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024507.1", "url": "https://www.ensembl.org/id/ENSGALP00010024507.1" } ] } }, { "isoform_ac": "A0A8V0Z7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8/entry#A0A8V0Z7T8-1", "sequence": { "sequence": "MMLDMATMARPWLWLWLCLQLPGFCTNLLSSQTPGYILTKTNNSTEIVCPMKGEHTGVYWYRWNQGRQHFEFLLFSSPLGKATYGTNISQEKFSIRGTSSYHSYRLHINRLHGSDNGTYYCCTIQSSQLILGTGTQLDVVDVLPLPSMPTLVPLTKKPMRCKPKNKAINKKGACTPMVWVPLAAGALLLLLSLIPTIRRFYRLRRRLWVRAHRRFPSNQAGMDH", "length": 224, "header": "tr|A0A8V0Z7T8-1|A0A8V0Z7T8_CHICK Isoform 1 of CD8b molecule pseudo OS=Gallus gallus OX=9031 GN=CD8BP PE=4 SV=1 CANONICAL=A0A8V0Z7T8-1" }, "locus": { "chromosome": "4", "start_pos": 85553722, "end_pos": 85539259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041913.1", "url": "https://www.ensembl.org/id/ENSGALT00010041913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024521.1", "url": "https://www.ensembl.org/id/ENSGALP00010024521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396175", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396175", "resource": "KEGG Pathway" }, { "id": "R-GGA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LBU4-1", "protein_name": "T-cell surface glycoprotein CD8 beta chain", "gene_name": "Cd8b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQPWLWLVFGVKLAALWSSSALLQTPRSLTVLTNQVAKVSCEAKTLPKTTLIYWLRQRRGPTKDKHFEFLASWNPSKGVATPGEGVKKESINVFSDITRYILNLTSVKLEDSGTYFCMMVGSPQLIFGSGTELSVVDALSTTAQTTKKTVIKKKQCPVPNPKAQKGLTCGLITLSLLVASLLVLLVSLGVAVHLHCLRRKARIHFMKQ", "length": 208 }, "evidence": [ { "id": "A0A8V0Z7T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z7T8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SVD7-1", "protein_name": "CD8 subunit beta", "gene_name": "CD8B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPRLWLLIAAQLSTLHGGSALLQTPSSVMAQTNQTVKLSCEARTFPTNTRIYWLRLRQAPSANSHYEFLALWIPNGNPVYGKETEKQLTVLQDSSRYLLQLRHVKPADSGNYFCMAVGNPELTFGKGTRLSVVDVFPTTAQPTKKTRPKKKICRLPNLVPPKGPACAPLIIGLLVAGLLVLLVSLGAAVHVYCLQRRAWHRLMKQ", "length": 206 }, "evidence": [ { "id": "A0A8V0Z7T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z7T8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P05541-1", "protein_name": "T-cell surface glycoprotein CD8 beta chain", "gene_name": "Cd8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPWLWLVFSVKLSALWGSSALLQTPSSLLVQTNQTAKMSCEAKTFPKGTTIYWLRELQDSNKNKHFEFLASRTSTKGIKYGERVKKNMTLSFNSTLPFLKIMDVKPEDSGFYFCAMVGSPMVVFGTGTKLTVVDVLPTTAPTKKTTLKKKQCPTPHPKTQKGLTCGLITLSLLVACILVLLVSLSVAIHFHCMRRRARIHFMKQFHK", "length": 208 }, "evidence": [ { "id": "A0A8V0Z7T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z7T8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10300-1", "protein_name": "T-cell surface glycoprotein CD8 beta chain", "gene_name": "Cd8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPWLWLVFSMKLAALWSSSALIQTPSSLLVQTNHTAKMSCEVKSISKLTSIYWLRERQDPKDKYFEFLASWSSSKGVLYGESVDKKRNIILESSDSRRPFLSIMNVKPEDSDFYFCATVGSPKMVFGTGTKLTVVDVLPTTAPTKKTTLKMKKKKQCPFPHPETQKGLTCSLTTLSLLVVCILLLLAFLGVAVYFYCVRRRARIHFMKQFHK", "length": 213 }, "evidence": [ { "id": "A0A8V0Z7T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z7T8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P10966-1", "protein_name": "T-cell surface glycoprotein CD8 beta chain", "gene_name": "CD8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQAPSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGVLVLLVSLGVAIHLCCRRRRARLRFMKQFYK", "length": 210 }, "evidence": [ { "id": "A0A8V0Z7T8", "url": "https://omabrowser.org/oma/group/A0A8V0Z7T8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" }, { "name": "MHC class I protein binding", "id": "GO:0042288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 121, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8A8-1", "uniprot_ac": "A0A8V0Z8A8", "uniprot_id": "A0A8V0Z8A8_CHICK", "mass": { "chemical_mass": 156873.0, "monoisotopic_mass": 156873.0 }, "refseq": { "ac": "XP_040507165", "name": "rho guanine nucleotide exchange factor 10-like protein isoform X10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507165" }, "gene_names": [ { "name": "ARHGEF10L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ] }, { "name": "ARHGEF10L", "type": "synonym", "evidence": [ { "id": "XP_040507165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507165" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 10-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#names_and_taxonomy" } ] }, { "name": "GrinchGEF", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 10-like protein isoform X10", "type": "synonym", "evidence": [ { "id": "XP_040507165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507165" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040507165.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507165" } ] }, { "annotation": "Acts as a guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PC33", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC33#function" }, { "database": "UniProtKB", "id": "ARBA00055620", "url": "https://www.uniprot.org/uniprotkb/ARBA00055620#function" }, { "database": "UniProtKB", "id": "A0A8V0Z0N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z7#function" }, { "database": "UniProtKB", "id": "A0A8V0Z838", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z838#function" }, { "database": "UniProtKB", "id": "A0A8V0Z842", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z842#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF10L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8", "locus": { "chromosome": "21", "start_pos": 123236, "end_pos": 149054, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018502", "url": "https://www.ensembl.org/id/ENSGALG00010018502" } ] } } ], "crossref": [ { "id": "ENSGALG00000043128", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419360", "url": "https://www.ncbi.nlm.nih.gov/gene/419360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PC33", "url": "https://www.orthodb.org/?gene=A0A1D5PC33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0N2", "url": "https://www.orthodb.org/?gene=A0A8V0Z0N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Z7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z838", "url": "https://www.orthodb.org/?gene=A0A8V0Z838", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z842", "url": "https://www.orthodb.org/?gene=A0A8V0Z842", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8A3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8A8", "url": "https://www.orthodb.org/?gene=A0A8V0Z8A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12877", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12877", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12877:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12877:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040507165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PC33", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z838", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z838", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z838-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z838-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z842", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z842", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z842-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLSVSHCTTWIRFPSLYFIFSLSPLSPPLPLAPQLHAFPPPSPTICKPGLERRVQHTDSTDPGAFAIFLVVFPVAEKKGGCVFFFFFSPLLSFSSPLEPTHQMYLKCKYEPPEETLQYKTETHVRAGKKNAKRRAKKKKKKKKLQRGRGCKVRWCTDSSIFRTGRLQEGRKIHPSSLLLRFCQGEIPFATILQEERLREGPRRSVWTPCAMASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1417, "header": "tr|A0A8V0Z8A8-1|A0A8V0Z8A8_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A1D5PC33-1", "sequence": { "sequence": "MKQERLREGPRRSVWTPCAMASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1224, "header": "tr|A0A1D5PC33-1|A0A8V0Z8A8_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 144667, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044924.1", "url": "https://www.ensembl.org/id/ENSGALT00010044924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026831.1", "url": "https://www.ensembl.org/id/ENSGALP00010026831.1" } ] } }, { "isoform_ac": "A0A8V0Z0N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z0N2-1", "sequence": { "sequence": "MASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDGECRRRLKEAEKLPPTPGISRGSLEHCGRGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKPVNPRGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1241, "header": "tr|A0A8V0Z0N2-1|A0A8V0Z8A8_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 139738, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044872.1", "url": "https://www.ensembl.org/id/ENSGALT00010044872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026791.1", "url": "https://www.ensembl.org/id/ENSGALP00010026791.1" } ] } }, { "isoform_ac": "A0A8V0Z6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z6Z7-1", "sequence": { "sequence": "MASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKLSPDLNRLKERYARTKRDILALRVGGKDMQELKQKYDWKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKPVNPRGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1249, "header": "tr|A0A8V0Z6Z7-1|A0A8V0Z8A8_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 139738, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044801.1", "url": "https://www.ensembl.org/id/ENSGALT00010044801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026723.1", "url": "https://www.ensembl.org/id/ENSGALP00010026723.1" } ] } }, { "isoform_ac": "A0A8V0Z838-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z838-1", "sequence": { "sequence": "MKQERLREGPRRSVWTPCAMASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1195, "header": "tr|A0A8V0Z838-1|A0A8V0Z838_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 144667, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044845.1", "url": "https://www.ensembl.org/id/ENSGALT00010044845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026767.1", "url": "https://www.ensembl.org/id/ENSGALP00010026767.1" } ] } }, { "isoform_ac": "A0A8V0Z842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z842-1", "sequence": { "sequence": "MASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDGECRRRLKEAEKLPPTPGISRGSLEHCGRAASASGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKPVNPRGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1246, "header": "tr|A0A8V0Z842-1|A0A8V0Z842_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 139738, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044851.1", "url": "https://www.ensembl.org/id/ENSGALT00010044851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026773.1", "url": "https://www.ensembl.org/id/ENSGALP00010026773.1" } ] } }, { "isoform_ac": "A0A8V0Z8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z8A3-1", "sequence": { "sequence": "MPLGRKDWERLREGPRRSVWTPCAMASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKLSPDLNRLKERYARTKRDILALRVGGKDMQELKQKYDWKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1268, "header": "tr|A0A8V0Z8A3-1|A0A8V0Z8A3_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 145654, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044936.1", "url": "https://www.ensembl.org/id/ENSGALT00010044936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026839.1", "url": "https://www.ensembl.org/id/ENSGALP00010026839.1" } ] } }, { "isoform_ac": "A0A8V0Z8A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8/entry#A0A8V0Z8A8-1", "sequence": { "sequence": "MGSLSVSHCTTWIRFPSLYFIFSLSPLSPPLPLAPQLHAFPPPSPTICKPGLERRVQHTDSTDPGAFAIFLVVFPVAEKKGGCVFFFFFSPLLSFSSPLEPTHQMYLKCKYEPPEETLQYKTETHVRAGKKNAKRRAKKKKKKKKLQRGRGCKVRWCTDSSIFRTGRLQEGRKIHPSSLLLRFCQGEIPFATILQEERLREGPRRSVWTPCAMASSQLPPCPTVGTVLASQPPSELPPGEEDLGEAFDFEDSDEEDEDSATEPSRGAVLQAPPRRHRATSSSTEGLVPEIQEGLPERVSNGETCEDPSDINSQTWKRKSGCRGDRFEFTAAEDDVIYDDVPCENLDANQDGRSLIYEDVQRGEELGWSSSEFESYSEESGEENKPEAEPAKHRASFQPKMTQLMKAAKSGTKDGLEKTKIAVMRKVTFLHRKEVPGDSEEEDTGFLEVTVSDMKHPPPELGPMPTGLSPQQVVRRHILGSIVQSERNYVESLKRILQDYRNPLMEMEPKVLSARKCQVVFFRLKEILQCHSMFQIALSSRVAEWDSAEKIGDLFVASFSKSMVLDVYSDYVNNFTTAMSLIKKACLTKPAFLDFLKKRQMASTDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPKGHADRLSLQLALTELETLAEKLNEQKRVADQVAEIQQLSKSISDRSSLSKLLNSGQRQLLLCETLTETVYGDRGQLIKSKERKVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWSTALPQVQVVEVGQESGAYDKDNVVIHNAGAKKHAPTGPASHNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRMMKVKEEEIHSANKCRLRLLLPGKPDKSGRPISVMVVFITPNPLSKISWVNCLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILSCHMPAFSSKALDLQLSAAVHNPVQSSLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRSVPRTVKSFPVASPVLCMEYIPEVAEGDTVGTEEPRAGAEQPPATLHPTVCLGLQDGSIAVYGSVDTGTQCLLTCKSPGMQPVLCLKHSPEYLFAGLQDGTVAAYPRSNGGLWDLTEQPTRLPVGTGPVRALLMLDETLWASCANQVTVLDASTLCAQQTFEAHPDTEASVTHMIKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFVLPGQRHVRVTSLLICQGLLWVGTDQGIIVLLPVPRLEGIPKITGKGMVSLNGHGGPVDFLAVALSTLAPDVLKGDQEEEEGEEEKPPELDGPPPREIRKKGILLQYRLRSTSHLPGQLLSVRDAPVGTVTPEHTEEDGSIYEMADDPDVWVRSRPCARDAPRKEISSVAIISGGRGYRNFNSEPQRRGGDADSTLLIWQLPLML", "length": 1417, "header": "tr|A0A8V0Z8A8-1|A0A8V0Z8A8_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 10-like protein OS=Gallus gallus OX=9031 GN=ARHGEF10L PE=1 SV=1 CANONICAL=A0A8V0Z8A8-1" }, "locus": { "chromosome": "21", "start_pos": 148855, "end_pos": 123853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044945.1", "url": "https://www.ensembl.org/id/ENSGALT00010044945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026844.1", "url": "https://www.ensembl.org/id/ENSGALP00010026844.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" }, { "name": "SREBP signaling pathway", "id": "GO:0032933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032933", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A8" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 473, "end_pos": 660, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 223 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 573, "end_pos": 575 }, { "start_pos": 837, "end_pos": 839 }, { "start_pos": 998, "end_pos": 1000 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7V4-1", "uniprot_ac": "A0A8V0Z7V4", "uniprot_id": "A0A8V0Z7V4_CHICK", "mass": { "chemical_mass": 127931.0, "monoisotopic_mass": 127931.0 }, "refseq": { "ac": "XP_015147505", "name": "ubiquitin carboxyl-terminal hydrolase 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147505" }, "gene_names": [ { "name": "USP8", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" } ] }, { "name": "USP8", "type": "synonym", "evidence": [ { "id": "XP_015147505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147505" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 8", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 8", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin isopeptidase Y", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 8", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 8", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015147505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147505" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147505.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4", "locus": { "chromosome": "10", "start_pos": 10852960, "end_pos": 10875449, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017377", "url": "https://www.ensembl.org/id/ENSGALG00010017377" } ] } } ], "crossref": [ { "id": "A0A8V0Z7V4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7V4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415451", "url": "https://www.ncbi.nlm.nih.gov/gene/415451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0V1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7U9", "url": "https://www.orthodb.org/?gene=A0A8V0Z7U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7V4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1358803", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1358803", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4641263", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807004", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAVASVPKELYLCTSLKDLNQKTEIKHEKTNSTKSYVQSALKIFKAAEECRLDRDEEKAYILYMKYVAVYNFIKKRPDFKQQQDYFHSILGPTNLKKAIEEAERLSDSLKLRYEEAEVRKKLEERDRQELQKKQEPKDDGKSSAKTSSESTVDCKGKSQRINGETKHSLERKDQAESFSAVTAEKLFAMMTDKTIELIIMDTRSLKDYQESCIPRSVSVPEEAISPGVTASWIEARLPEDSKDPWKKRGHFDYVVLLDWFSSAEDLNIGTTLRSLKDALFKWESKTILQNEPLVLEGGYENWLLCFPQYTTNAKVTPPQHGKSEAVTVSLDFTYPSLEEPAPAPPVAPIKPSPTEVVENEETGANLEERLKSLNRPSVEGAAVPKPDSSFVVNPASITRSIPEVDRSKKPSIKIPDDNKSKSESTLSDSQPIEKGRVVPDRSTKPLLDAKSVLTEEEKSRVHAETAALMEKNRREKELRERQKEEQKERIKREKEEQEQKAKEEQREKEHKEKLQQSKEEREQKERDEQIKREQEEKEKEKARKEAIEAKKQNKNEPESIDAKKVETDKISIEKREKGTRTPDTQRRVLGDVSPNKQTEVKGQPDSGAQKPGPLREDSEQDTERLKSQREPLTRARSEEMGRVIPGLPDGWAKFLDPITGTFRYYHSPTNTVQMYPPEMAPSSTPPATPPTRKPKPQVAVEREREHSKLKRSYSSPDITQAIQEEEKKRIPVTPAVNRENKPAYYPKTEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLAEYFNKNLYQDDINRSNFLGHKGEVAEEFGVIMKALWTGQYKYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDLKAAELAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLETLDLSQYVIGPKNNLKRYNLFSVSNHYGGLDGGHYTAYCKNASKQRWFKFDDHEVSEISASSVKSSAAYILFYTSYEQRAVDMAT", "length": 1115, "header": "tr|A0A8V0Z7V4-1|A0A8V0Z7V4_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 8 OS=Gallus gallus OX=9031 GN=USP8 PE=1 SV=1 CANONICAL=A0A8V0Z7V4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#A0A8V0Z0V1-1", "sequence": { "sequence": "MPAVASVPKELYLCTSLKDLNQKTEIKHEKTNSTKSYVQSALKIFKAAEECRLDRDEEKAYILYMKYVAVYNFIKKRPDFKQQQDYFHSILGPTNLKKAIEEAERLSDSLKLRYEEAEVRKKLEERDRQELQKKQEPKDDGKSSAKTSSESTVDCKGKSQRINGETKHSLERKDQAESFSGAVTAEKLFAMMTDKTIELIIMDTRSLKDYQESCIPRSVSVPEEAISPGVTASWIEARLPEDSKDPWKKRGHFDYVVLLDWFSSAEDLNIGTTLRSLKDALFKWESKTILQNEPLVLEGGYENWLLCFPQYTTNAKVTPPQHGKSEAVTVSLDFTYPSLEEPAPAPPVAPIKPSPTEVVENEETGANLEERLKSLNRPSVEGAAVPKPDSSFVVNPASITRSIPEVDRSKKPSIKIPDDNKSKSESTLSDSQPIEKGRVVPDRSTKPLLDAKSVLTEEEKSRVHAETAALMEKNRREKELRERQKEEQKERIKREKEEQEQKAKEEQREKEHKEKLQQSKEEREQKERDEQIKREQEEKEKEKARKEAIEAKKQNKNEPESIDAKKVETDKISIEKREKGTRTPDTQRRVLGDVSPNKSQREPLTRARSEEMGRVIPGLPDGWAKFLDPITGTFRYYHSPTNTVQMYPPEMAPSSTPPATPPTRKPKPQVAVEREREHSKLKRSYSSPDITQAIQEEEKKRIPVTPAVNRENKPAYYPKTEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLAEYFNKNLYQDDINRSNFLGHKGEVAEEFGVIMKALWTGQYKYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDLKAAELAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLETLDLSQYVIGPKNNLKRYNLFSVSNHYGGLDGGHYTAYCKNASKQRWFKFDDHEVSEISASSVKSSAAYILFYTSYEQRAVDMAT", "length": 1086, "header": "tr|A0A8V0Z0V1-1|A0A8V0Z7V4_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Gallus gallus OX=9031 GN=USP8 PE=1 SV=1 CANONICAL=A0A8V0Z7V4-1" }, "locus": { "chromosome": "10", "start_pos": 10868983, "end_pos": 10853730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041935.1", "url": "https://www.ensembl.org/id/ENSGALT00010041935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024539.1", "url": "https://www.ensembl.org/id/ENSGALP00010024539.1" } ] } }, { "isoform_ac": "A0A8V0Z7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#A0A8V0Z7U9-1", "sequence": { "sequence": "MPAVASVPKELYLCTSLKDLNQKTEIKHEKTNSTKSYVQSALKIFKAAEECRLDRDEEKAYILYMKYVAVYNFIKKRPDFKQQQDYFHSILGPTNLKKAIEEAERLSDSLKLRYEEAEVRKKLEERDRQELQKKQEPKDDGKSSAKTSSESTVDCKGKSQRINGETKHSLERKDQAESFSGAVTAEKLFAMMTDKTIELIIMDTRSLKDYQESCIPRSVSVPEEAISPGVTASWIEARLPEDSKDPWKKRGHFDYVVLLDWFSSAEDLNIGTTLRSLKDALFKWESKTILQNEPLVLEGGYENWLLCFPQYTTNAKVTPPQHGKSEAVTVSLDFTYPSLEEPAPAPPVAPIKPSPTEVVENEETGANLEERLKSLNRPSVEGAAVPKPDSSFVVNPASITRSIPEVDRSKKPSIKIPDDNKSKSESTLSDSQPIEKGRVVPDRSTKPLLDAKSVLTEEEKSRVHAETAALMEKNRREKELRERQKEEQKERIKREKEEQEQKAKEEQREKEHKEKLQQSKEEREQKERDEQIKREQEEKEKEKARKEAIEAKKQNKNEPESIDAKKVETDKISIEKREKGTRTPDTQRRVLGDVSPNKQTEVKGQPDSGAQKPGPLREDSEQDTERLKSQREPLTRARSEEMGRVIPGLPDGWAKFLDPITGTFRYYHSPTNTVQMYPPEMAPSSTPPATPPTRKPKPQVAVEREREHSKLKRSYSSPDITQAIQEEEKKRIPVTPAVNRENKSNFLGHKGEVAEEFGVIMKALWTGQYKYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDLKAAELAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLETLDLSQYVIGPKNNLKRYNLFSVSNHYGGLDGGHYTAYCKNASKQRWFKFDDHEVSEISASSVKSSAAYILFYTSYEQRAVDMAT", "length": 1045, "header": "tr|A0A8V0Z7U9-1|A0A8V0Z7U9_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 8 OS=Gallus gallus OX=9031 GN=USP8 PE=1 SV=1 CANONICAL=A0A8V0Z7V4-1" }, "locus": { "chromosome": "10", "start_pos": 10868983, "end_pos": 10853730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041932.1", "url": "https://www.ensembl.org/id/ENSGALT00010041932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024536.1", "url": "https://www.ensembl.org/id/ENSGALP00010024536.1" } ] } }, { "isoform_ac": "A0A8V0Z7V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4/entry#A0A8V0Z7V4-1", "sequence": { "sequence": "MPAVASVPKELYLCTSLKDLNQKTEIKHEKTNSTKSYVQSALKIFKAAEECRLDRDEEKAYILYMKYVAVYNFIKKRPDFKQQQDYFHSILGPTNLKKAIEEAERLSDSLKLRYEEAEVRKKLEERDRQELQKKQEPKDDGKSSAKTSSESTVDCKGKSQRINGETKHSLERKDQAESFSAVTAEKLFAMMTDKTIELIIMDTRSLKDYQESCIPRSVSVPEEAISPGVTASWIEARLPEDSKDPWKKRGHFDYVVLLDWFSSAEDLNIGTTLRSLKDALFKWESKTILQNEPLVLEGGYENWLLCFPQYTTNAKVTPPQHGKSEAVTVSLDFTYPSLEEPAPAPPVAPIKPSPTEVVENEETGANLEERLKSLNRPSVEGAAVPKPDSSFVVNPASITRSIPEVDRSKKPSIKIPDDNKSKSESTLSDSQPIEKGRVVPDRSTKPLLDAKSVLTEEEKSRVHAETAALMEKNRREKELRERQKEEQKERIKREKEEQEQKAKEEQREKEHKEKLQQSKEEREQKERDEQIKREQEEKEKEKARKEAIEAKKQNKNEPESIDAKKVETDKISIEKREKGTRTPDTQRRVLGDVSPNKQTEVKGQPDSGAQKPGPLREDSEQDTERLKSQREPLTRARSEEMGRVIPGLPDGWAKFLDPITGTFRYYHSPTNTVQMYPPEMAPSSTPPATPPTRKPKPQVAVEREREHSKLKRSYSSPDITQAIQEEEKKRIPVTPAVNRENKPAYYPKTEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLAEYFNKNLYQDDINRSNFLGHKGEVAEEFGVIMKALWTGQYKYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDLKAAELAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLETLDLSQYVIGPKNNLKRYNLFSVSNHYGGLDGGHYTAYCKNASKQRWFKFDDHEVSEISASSVKSSAAYILFYTSYEQRAVDMAT", "length": 1115, "header": "tr|A0A8V0Z7V4-1|A0A8V0Z7V4_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 8 OS=Gallus gallus OX=9031 GN=USP8 PE=1 SV=1 CANONICAL=A0A8V0Z7V4-1" }, "locus": { "chromosome": "10", "start_pos": 10868983, "end_pos": 10853730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041939.1", "url": "https://www.ensembl.org/id/ENSGALT00010041939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024541.1", "url": "https://www.ensembl.org/id/ENSGALP00010024541.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 685, "start_aa": "Thr", "end_pos": 685, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr685", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 689, "start_aa": "Thr", "end_pos": 689, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr689", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 734, "start_aa": "Thr", "end_pos": 734, "end_aa": "Thr", "residue": "Thr", 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], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V4", "url": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-917720" ], "output_participant_list": [ "R-GGA-1358714" ], "enzyme_list": [ "A0A3Q2U4X3-1", "A0A8V0Z7V4-1" ], "evidence": [ { "id": "R-GGA-1358791", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1358791" } ] }, { "id": "R-GGA-1358795", "name": "Deubiquitination of RNF41 by P-USP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A2W7-1", "A0A8V0Z7V4-1" ], "evidence": [ { "id": "R-GGA-1358795", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1358795" } ] }, { "id": "R-GGA-1358797", "name": "Ubiquitinated RNF41 binds P-USP8", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A2W7-1", "A0A8V0Z7V4-1" ], "evidence": [ { "id": "R-GGA-1358797", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1358797" } ] }, { "id": "R-GGA-4641236", "name": "USP8 deubiquitinates FZD to potentiate WNT signaling", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z7V4-1" ], "evidence": [ { "id": "R-GGA-4641236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641236" } ] }, { "id": "R-GGA-6782628", "name": "USP8 deubiquitinates STAM2:HGS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z7V4-1" ], "evidence": [ { "id": "R-GGA-6782628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782628" } ] }, { "id": "R-GGA-8875443", "name": "USP8 deubiquitinates LRIG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"evidence": [ { "id": "A0A8V0Z7V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V4" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 774, "end_pos": 1106, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8F0-1", "uniprot_ac": "A0A8V0Z8F0", "uniprot_id": "A0A8V0Z8F0_CHICK", "mass": { "chemical_mass": 120957.0, "monoisotopic_mass": 120957.0 }, "refseq": {}, "gene_names": [ { "name": "GLTSCR1L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0" } ] } ], "protein_names": [ { "name": "BICRA like chromatin remodeling complex associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLTSCR1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z8F0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8F0", "database": "AlphaFoldDB", "categories": [] }, { "id": "428568", "url": "https://www.ncbi.nlm.nih.gov/gene/428568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428568", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQFHPVP", "url": "https://omabrowser.org/oma/group/DQFHPVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0Y8", "url": "https://www.orthodb.org/?gene=A0A8V0Z0Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6W9", "url": "https://www.orthodb.org/?gene=A0A8V0Z6W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7F7", "url": "https://www.orthodb.org/?gene=A0A8V0Z7F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8E2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8F0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9933947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCNVVGARGLTATSVSRNSKDATRPTHAEPTKDSLNSVLLIASSLVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1129, "header": "tr|A0A8V0Z8F0-1|A0A8V0Z8F0_CHICK Isoform 1 of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#A0A8V0Z0Y8-1", "sequence": { "sequence": "MLQKEIIASFVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1094, "header": "tr|A0A8V0Z0Y8-1|A0A8V0Z8F0_CHICK Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "locus": { "chromosome": "3", "start_pos": 22796646, "end_pos": 22776717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045006.1", "url": "https://www.ensembl.org/id/ENSGALT00010045006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026882.1", "url": "https://www.ensembl.org/id/ENSGALP00010026882.1" } ] } }, { "isoform_ac": "A0A8V0Z6W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#A0A8V0Z6W9-1", "sequence": { "sequence": "MDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1083, "header": "tr|A0A8V0Z6W9-1|A0A8V0Z8F0_CHICK Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "locus": { "chromosome": "3", "start_pos": 22796646, "end_pos": 22778602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045021.1", "url": "https://www.ensembl.org/id/ENSGALT00010045021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026894.1", "url": "https://www.ensembl.org/id/ENSGALP00010026894.1" } ] } }, { "isoform_ac": "A0A8V0Z7F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#A0A8V0Z7F7-1", "sequence": { "sequence": "MDSLNSVLLIASSLVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1098, "header": "tr|A0A8V0Z7F7-1|A0A8V0Z8F0_CHICK Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "locus": { "chromosome": "3", "start_pos": 22796646, "end_pos": 22776501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045010.1", "url": "https://www.ensembl.org/id/ENSGALT00010045010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026886.1", "url": "https://www.ensembl.org/id/ENSGALP00010026886.1" } ] } }, { "isoform_ac": "A0A8V0Z8E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#A0A8V0Z8E2-1", "sequence": { "sequence": "MQMEASKEQQSGKNEGAYLLQDSLNSVLLIASSLVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1118, "header": "tr|A0A8V0Z8E2-1|A0A8V0Z8E2_CHICK Computationally mapped isoform of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "locus": { "chromosome": "3", "start_pos": 22796646, "end_pos": 22777998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045001.1", "url": "https://www.ensembl.org/id/ENSGALT00010045001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026880.1", "url": "https://www.ensembl.org/id/ENSGALP00010026880.1" } ] } }, { "isoform_ac": "A0A8V0Z8F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0/entry#A0A8V0Z8F0-1", "sequence": { "sequence": "MCNVVGARGLTATSVSRNSKDATRPTHAEPTKDSLNSVLLIASSLVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1129, "header": "tr|A0A8V0Z8F0-1|A0A8V0Z8F0_CHICK Isoform 1 of BICRA like chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=GLTSCR1L PE=4 SV=1 CANONICAL=A0A8V0Z8F0-1" }, "locus": { "chromosome": "3", "start_pos": 22796646, "end_pos": 22768224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045014.1", "url": "https://www.ensembl.org/id/ENSGALT00010045014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026890.1", "url": "https://www.ensembl.org/id/ENSGALP00010026890.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428568", "resource": "KEGG Pathway" }, { "id": "R-GGA-9933947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933947", "resource": "Reactome", "description": "Formation of the non-canonical BAF (ncBAF) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LAU3-1", "protein_name": "BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2", "gene_name": "Bicral", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSSDDLTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPDLGEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQTPTNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSAYNVNSLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNAAVQLVSGQTFATSGSPVIVNHASPQMVGGQMPLQRASPTVLHLSPGQSSASQGRPGFTAMPSVTSMSGPARFPTVSSASTAHTSLGSTVQSGASGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKPTSTFSNTPGTQQQFFCQAQKKCLTQPSPLPTAKTTDGLRQSQIPGLLSTALPGQDSGSKVMPASLGTAQPQQENTVGSSPSQTTVQVDSHSGQKRPATKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLSDTVQRLLSYHVCQGSTPTEEDLRKVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKVDEAAPEAPLDRSDQHRSKTSSLHQAPRSQSRDRPKAGMAEATNHDQFHLVPNHIVVSGEGSVSKKSEGHGRTLKYDKGGLGQYRGAPEDKGSRRDPANASGCSPGPEGHRKTMPRPDHGPESKLPGILASAHLEMPCLDSFQDRALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKKAGRPQSDPAASGAMDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1074 }, "evidence": [ { "id": "A0A8V0Z8F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1EG31-1", "protein_name": "BICRA like chromatin remodeling complex associated protein", "gene_name": "BICRAL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSSLKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASISSSQQFAQAPLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQPAPSNVSGGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPVPMGQQNTYSVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNPRKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSSSVHHVQTINGQLLQTQPPQLISGPVASEHVMLNRTSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFAASGSPVIVNHASSQIVSGQMPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMSGPSRFPAVSSSSTAHPSLGSAVQSGASGSNFTGDQLAQPNRTPVPVSVSHRLPVPSSKSTSTFSNAPGAGTQQPFFCQAQKKSLNQTSPISASKTAEGLRQAPIPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSSPGQPAVQVDGHSGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERAALSRDKRLALVDPEGFQADFCCSFKPSKAAPETQFGRSDQPGSKAASSVHLPAKAQSRDRAKPGMAEPTNHDQFHLVPNHVVVSAEGSISKKTECLSRALKFDKMGSVQYQSASDDKGSRRDSLKGSECSPGPEGHRKNSSRPDHGPESKPSSILADSHLELTCNSSFQDKSLRNSPKNEVLHTDIMRGSGEPQPDLQLTKSLETTFKNILELKKAGRQPQSDPTVSGSVELDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1080 }, "evidence": [ { "id": "A0A8V0Z8F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0L4W7-1", "protein_name": "BICRA like chromatin remodeling complex associated protein", "gene_name": "Bicral", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTVPLQKEAQRAAAPLRPHCQSLCSDSLSSFLAVVMDDDDDSCLLDLIGDPQALNYFLHGPSSKSSGDDVTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLASSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSSVSGGLLVHRQTPNGNSLFGNPTSSPGAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSTYNVNSLGLQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNARKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLVQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYAGQMLNNQSAAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMASVSSMSGPARFPAVSSASTAHPTLGPAVQSGASGSNFTGDQLTQANRTPVPVSVSHRLPVSASKSPSTLSSTPGTQQQFFCQAPKKCLNQTAPIPTPIPTSKTTDSLRQPQIPGLLSTALPGQDCGSKIMPAPLGTTQPQQENSVGSSPSQTAVQVDSHSGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLTDTVQRLLSYHVCQGSMPTEEDLSKVDSEFEEVATQLLKRTHAMLNKYRSLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAAPETPLDRSDQHRSKTSSLHQVPRAQSRDRAKPGVAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDKGVLGQYRGPPEDKGGRRDPAKASGCSPGPEGHRKTLPRPDHGSESKLPGILASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNAGRPQNDPAASGAVDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1114 }, "evidence": [ { "id": "A0A8V0Z8F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AI39-1", "protein_name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "gene_name": "BICRAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNDDLTNAGYSAANSNSIFANSSNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPDLTEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSSQISGSGQIQLIGSFGNHPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSTGGSIVIHSPMGQPHAPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYTGPMLNNQNTAVHLVSGQTFAASGSPVIANHASPQLVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPSVTSMSGPSRFPAVSSASTAHPSLGSAVQSGSSGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKSTSTFSNTPGTGTQQQFFCQAQKKCLNQTSPISAPKTTDGLRQAQIPGLLSTTLPGQDSGSKVISASLGTAQPQQEKVVGSSPGHPAVQVESHSGGQKRPAAKQLTKGAFILQQLQRDQAHTVTPDKSHFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHETQFGRSDQHGSKASSSLQPPAKAQGRDRAKTGVTEPMNHDQFHLVPNHIVVSAEGNISKKTECLGRALKFDKVGLVQYQSTSEEKASRREPLKASQCSPGPEGHRKTSSRSDHGTESKLSSILADSHLEMTCNNSFQDKSLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQPQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1079 }, "evidence": [ { "id": "A0A8V0Z8F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CHH5-1", "protein_name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "gene_name": "Bicral", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSSKSGSDDVTNAGYSAANSNSIFANSTNADPKSALKGVSDQLGEGPSDGLPLASSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPVQMGQQSAYNVNNLGIQQHHAQQGISFAPTSSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSGTGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQAINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPAVSGMAGPARFPAVSSASTAHPTLGPTVQSGAPGSNFTGDQLTQANRTPAPVSVSHRLPVSASKSPSTLSNTPGTQQQFFCQAQKKCLNQTSPIPTSKTTDGLRPSQIPGLLSTALPGQDSGSKIMPATLGATQAQPESSVGSSPSQTAVQVDSHPGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLNDTVQRLLSYHVCQGSMPTEEDLRQVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAVPETPLDRSDQHRSKTSSLHQVPRAQSRDRAKPGMAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDRGVLGQYRGPPEDKGGRRDPAKVSRCSPGPEGHRKSLPRPDHGSESKLPGVLASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNSGRPPSDPTASGAADLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1074 }, "evidence": [ { "id": "A0A8V0Z8F0", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1091, "end_pos": 1093, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F0" }, { "id": "PF15249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GLTSCR protein conserved", "eco_id": "ECO_0000259", "start_pos": 759, "end_pos": 859, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 1020, "end_pos": 1022 }, { "start_pos": 1091, "end_pos": 1093 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8H9-1", "uniprot_ac": "A0A8V0Z8H9", "uniprot_id": "A0A8V0Z8H9_CHICK", "mass": { "chemical_mass": 63532.0, "monoisotopic_mass": 63532.0 }, "refseq": {}, "gene_names": [ { "name": "CORO2B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CORO2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9", "locus": { "chromosome": "10", "start_pos": 19260648, "end_pos": 19232897, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017482", "url": "https://www.ensembl.org/id/ENSGALG00010017482" } ] } } ], "crossref": [ { "id": "A0A8V0Z8H9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008043", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008043", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415561", "url": "https://www.ncbi.nlm.nih.gov/gene/415561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415561", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EREMAIW", "url": "https://omabrowser.org/oma/group/EREMAIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AYV8", "url": "https://www.orthodb.org/?gene=A0A3Q3AYV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z112", "url": "https://www.orthodb.org/?gene=A0A8V0Z112", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8G7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8H9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C2B6", "url": "https://www.orthodb.org/?gene=E1C2B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q3AYV8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AYV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AYV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z112", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z112", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z112-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z112-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2B6", "url": "https://www.uniprot.org/uniprotkb/E1C2B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2B6-1", "url": "https://www.uniprot.org/uniprotkb/E1C2B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGWNSTALLPALHACKCCSRHTAYPRRCTPTLAPNSVHLFRAHLAVLRPRAVLPCAGSRSARDPLSPTPAPGGRRCPTSPRSPAAQMSWRPQYRSSKFRNVYGKVASREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIENIIASCSEDTSVRIWEIPEGGLKRNMTEAVLELYGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLATSCKDKKLRVVEPRSGRVLQEASCKNHRVNRVVFLGSTKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIGSEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 562, "header": "tr|A0A8V0Z8H9-1|A0A8V0Z8H9_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO2B PE=1 SV=1 CANONICAL=A0A8V0Z8H9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#A0A3Q3AYV8-1", "sequence": { "sequence": "MHTAGHRALALAHPSSRLCMTVTKMSWRPQYRSSKFRNVYGKVASREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIENIIASCSEDTSVRIWEIPEGGLKRNMTEAVLELYGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLATSCKDKKLRVVEPRSGRVLQEASCKNHRVNRVVFLGSTKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIGSEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 499, "header": "tr|A0A3Q3AYV8-1|A0A8V0Z8H9_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO2B PE=1 SV=1 CANONICAL=A0A8V0Z8H9-1" }, "locus": { "chromosome": "10", "start_pos": 19259879, "end_pos": 19233224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042229.1", "url": "https://www.ensembl.org/id/ENSGALT00010042229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024746.1", "url": "https://www.ensembl.org/id/ENSGALP00010024746.1" } ] } }, { "isoform_ac": "A0A8V0Z112-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#A0A8V0Z112-1", "sequence": { "sequence": "MHTAGHRALAMSWRPQYRSSKFRNVYGKVASREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIENIIASCSEDTSVRIWEIPEGGLKRNMTEAVLELYGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLATSCKDKKLRVVEPRSGRVLQEASCKNHRVNRVVFLGSTKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIGSEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 485, "header": "tr|A0A8V0Z112-1|A0A8V0Z8H9_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO2B PE=1 SV=1 CANONICAL=A0A8V0Z8H9-1" }, "locus": { "chromosome": "10", "start_pos": 19259879, "end_pos": 19233224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042234.1", "url": "https://www.ensembl.org/id/ENSGALT00010042234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024749.1", "url": "https://www.ensembl.org/id/ENSGALP00010024749.1" } ] } }, { "isoform_ac": "A0A8V0Z8G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#A0A8V0Z8G7-1", "sequence": { "sequence": "MGTSSEDAFLHTSALDSFVLCGCSAPISPQPTAVARSRAQGSLGTFQLCCHPDGRHLFILPTVDQMHPVASTVWRWAGTKVKVLYNPAQSRDRCLAEHELSPGMLSFWFDSVQQTSSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 236, "header": "tr|A0A8V0Z8G7-1|A0A8V0Z8G7_CHICK Computationally mapped isoform of Coronin 2B OS=Gallus gallus OX=9031 GN=CORO2B PE=4 SV=1 CANONICAL=A0A8V0Z8H9-1" }, "locus": { "chromosome": "10", "start_pos": 19259879, "end_pos": 19258498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042220.1", "url": "https://www.ensembl.org/id/ENSGALT00010042220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024738.1", "url": "https://www.ensembl.org/id/ENSGALP00010024738.1" } ] } }, { "isoform_ac": "A0A8V0Z8H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#A0A8V0Z8H9-1", "sequence": { "sequence": "MSGWNSTALLPALHACKCCSRHTAYPRRCTPTLAPNSVHLFRAHLAVLRPRAVLPCAGSRSARDPLSPTPAPGGRRCPTSPRSPAAQMSWRPQYRSSKFRNVYGKVASREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIENIIASCSEDTSVRIWEIPEGGLKRNMTEAVLELYGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLATSCKDKKLRVVEPRSGRVLQEASCKNHRVNRVVFLGSTKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIGSEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 562, "header": "tr|A0A8V0Z8H9-1|A0A8V0Z8H9_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO2B PE=1 SV=1 CANONICAL=A0A8V0Z8H9-1" }, "locus": { "chromosome": "10", "start_pos": 19259879, "end_pos": 19238806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042231.1", "url": "https://www.ensembl.org/id/ENSGALT00010042231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024748.1", "url": "https://www.ensembl.org/id/ENSGALP00010024748.1" } ] } }, { "isoform_ac": "E1C2B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9/entry#E1C2B6-1", "sequence": { "sequence": "MRDLHKSSVLGSKHGSLMSWRPQYRSSKFRNVYGKVASREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIENIIASCSEDTSVRIWEIPEGGLKRNMTEAVLELYGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLATSCKDKKLRVVEPRSGRVLQEASCKNHRVNRVVFLGSTKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEIGSEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALTPDEWLSGVNRDPILMSLKEGYKRTSKIVFKAPVREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKDELSQKDIRIRQLQLELKNLRNSPKNN", "length": 492, "header": "tr|E1C2B6-1|A0A8V0Z8H9_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO2B PE=1 SV=3 CANONICAL=A0A8V0Z8H9-1" }, "locus": { "chromosome": "10", "start_pos": 19259879, "end_pos": 19242347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042224.1", "url": "https://www.ensembl.org/id/ENSGALT00010042224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024742.1", "url": "https://www.ensembl.org/id/ENSGALP00010024742.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 454, "start_aa": "Thr", "end_pos": 454, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr454", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 69, "start_aa": "Thr", "end_pos": 69, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr69", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415561", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MRD3-1", "protein_name": "Coronin", "gene_name": "CORO2B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTVTKAQPKCHLLQEAFSDLSSLQTPSSCHCCVEMVLAEHTCLPCQRMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSPKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC", "length": 522 }, "evidence": [ { "id": "A0A8V0Z8H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8H9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LMV9-1", "protein_name": "Coronin", "gene_name": "Coro2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGVNRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC", "length": 480 }, "evidence": [ { "id": "A0A8V0Z8H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BH44-1", "protein_name": "Coronin-2B", "gene_name": "Coro2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC", "length": 480 }, "evidence": [ { "id": "A0A8V0Z8H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQ03-1", "protein_name": "Coronin-2B", "gene_name": "CORO2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC", "length": 480 }, "evidence": [ { "id": "A0A8V0Z8H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "talin binding", "id": "GO:1990147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H9" }, { "id": "SM01166", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1899", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 156, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 69, 454 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7Q5-1", "uniprot_ac": "A0A8V0Z7Q5", "uniprot_id": "A0A8V0Z7Q5_CHICK", "mass": { "chemical_mass": 18789.0, "monoisotopic_mass": 18789.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Macro domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z7Q5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7Q5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z762", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z762", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z762-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z762-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYPGNKRKKLWREEKERLLKMTLEERRKEYLREYVALKDIPTWMEEMRSKNESDGDQEGWTQSGGPLGSYKSQPLKGEELLDLGCFLRRSAAQLREPLHLQGENAKEDVQGKRSLSEKVSLYRGDITLLEVDAIVNAGFYLGFGLCTVPLPAQRCSSNSFQDW", "length": 163, "header": "tr|A0A8V0Z7Q5-1|A0A8V0Z7Q5_CHICK Isoform 1 of Macro domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z7Q5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5/entry#A0A8V0Z1A2-1", "sequence": { "sequence": "MYPGNKRKKLWREEKERLLKMTLEERRKEYLREYVALKDIPTWMEEMRSKNESDGENAKEDVQGKRSLSEKVSLYRGDITLLEVDAIVNAGKSLLFPLDKLRWNYTLHGVPSTKR", "length": 115, "header": "tr|A0A8V0Z1A2-1|A0A8V0Z7Q5_CHICK Computationally mapped isoform of Macro domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z7Q5-1" }, "locus": { "chromosome": "3", "start_pos": 4869170, "end_pos": 4765730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045197.1", "url": "https://www.ensembl.org/id/ENSGALT00010045197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026988.1", "url": "https://www.ensembl.org/id/ENSGALP00010026988.1" } ] } }, { "isoform_ac": "A0A8V0Z762-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5/entry#A0A8V0Z762-1", "sequence": { "sequence": "MYPGNKRKKLWREEKERLLKMTLEERRKEYLREYVALKDIPTWMEEMRSKNESDGENAKEDVQGKRSLSEKVSLYRGDITLLEVDAIVNADAAEAPRAWKSFRWHTSAGGADDPALTDGR", "length": 120, "header": "tr|A0A8V0Z762-1|A0A8V0Z7Q5_CHICK Computationally mapped isoform of Macro domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z7Q5-1" }, "locus": { "chromosome": "3", "start_pos": 4878836, "end_pos": 4765730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045201.1", "url": "https://www.ensembl.org/id/ENSGALT00010045201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026990.1", "url": "https://www.ensembl.org/id/ENSGALP00010026990.1" } ] } }, { "isoform_ac": "A0A8V0Z7Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5/entry#A0A8V0Z7Q5-1", "sequence": { "sequence": "MYPGNKRKKLWREEKERLLKMTLEERRKEYLREYVALKDIPTWMEEMRSKNESDGDQEGWTQSGGPLGSYKSQPLKGEELLDLGCFLRRSAAQLREPLHLQGENAKEDVQGKRSLSEKVSLYRGDITLLEVDAIVNAGFYLGFGLCTVPLPAQRCSSNSFQDW", "length": 163, "header": "tr|A0A8V0Z7Q5-1|A0A8V0Z7Q5_CHICK Isoform 1 of Macro domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z7Q5-1" }, "locus": { "chromosome": "3", "start_pos": 4812280, "end_pos": 4765730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045193.1", "url": "https://www.ensembl.org/id/ENSGALT00010045193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026987.1", "url": "https://www.ensembl.org/id/ENSGALP00010026987.1" } ] } }, { "isoform_ac": "A0A8V0Z7Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Q5/entry#A0A8V0Z7Q9-1", "sequence": { "sequence": "MYPGNKRKKLWREEKERLLKMTLEERRKEYLREYVALKDIPTWMEEMRSKNESDGENAKEDVQGKRSLSEKVSLYRGDITLLEVDAIVNAGEVLR", "length": 95, "header": "tr|A0A8V0Z7Q9-1|A0A8V0Z7Q9_CHICK Computationally mapped isoform of Macro domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z7Q5-1" }, "locus": { "chromosome": "3", "start_pos": 4922684, "end_pos": 4765730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045206.1", "url": "https://www.ensembl.org/id/ENSGALT00010045206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026992.1", "url": "https://www.ensembl.org/id/ENSGALP00010026992.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8K4-1", "uniprot_ac": "A0A8V0Z8K4", "uniprot_id": "A0A8V0Z8K4_CHICK", "mass": { "chemical_mass": 22417.0, "monoisotopic_mass": 22417.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC28B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 28B", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC28B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4", "locus": { "chromosome": "23", "start_pos": 5527943, "end_pos": 5529649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017491", "url": "https://www.ensembl.org/id/ENSGALG00010017491" } ] } } ], "crossref": [ { "id": "A0A8V0Z8K4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "419647", "url": "https://www.ncbi.nlm.nih.gov/gene/419647", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419647", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419647", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKYKRAH", "url": "https://omabrowser.org/oma/group/GKYKRAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1J7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8K4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13400:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13400:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z1J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEERRKKRSPRGQPAPARASQLLPTSKSASFALPLPALPSQHARPRRSVLRVGRETNPCGLSGAGGVVWWCHCPCPPCRASKERVRAGAARGAPLQHSFLTEVSDVCEMEGGLLGLLSDFHSGKLQAFGKECSFEQLEHVREMQEKLARLHFGLDLCMEELPEEQKKVVADRNLDQLLAHLEELSSSIQKLHLAESPSPEEAAA", "length": 204, "header": "tr|A0A8V0Z8K4-1|A0A8V0Z8K4_CHICK Isoform 1 of Coiled-coil domain containing 28B OS=Gallus gallus OX=9031 GN=CCDC28B PE=4 SV=1 CANONICAL=A0A8V0Z8K4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4/entry#A0A8V0Z1J7-1", "sequence": { "sequence": "MEERRKKRSPRGQPAPARASQLLPTSKSASFALPLPALPSQHARPRRASKERVRAGAARGAPLQHSFLTEVSDVCEMEGGLLGLLSDFHSGKLQAFGKECSFEQLEHVREMQEKLARLHFGLDLCMEELPEEQKKVVADRNLDQLLAHLEELSSSIQKLHLAESPSPEEAAA", "length": 172, "header": "tr|A0A8V0Z1J7-1|A0A8V0Z8K4_CHICK Computationally mapped isoform of Coiled-coil domain containing 28B OS=Gallus gallus OX=9031 GN=CCDC28B PE=4 SV=1 CANONICAL=A0A8V0Z8K4-1" }, "locus": { "chromosome": "23", "start_pos": 5529045, "end_pos": 5528133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042298.1", "url": "https://www.ensembl.org/id/ENSGALT00010042298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024791.1", "url": "https://www.ensembl.org/id/ENSGALP00010024791.1" } ] } }, { "isoform_ac": "A0A8V0Z8K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4/entry#A0A8V0Z8K4-1", "sequence": { "sequence": "MEERRKKRSPRGQPAPARASQLLPTSKSASFALPLPALPSQHARPRRSVLRVGRETNPCGLSGAGGVVWWCHCPCPPCRASKERVRAGAARGAPLQHSFLTEVSDVCEMEGGLLGLLSDFHSGKLQAFGKECSFEQLEHVREMQEKLARLHFGLDLCMEELPEEQKKVVADRNLDQLLAHLEELSSSIQKLHLAESPSPEEAAA", "length": 204, "header": "tr|A0A8V0Z8K4-1|A0A8V0Z8K4_CHICK Isoform 1 of Coiled-coil domain containing 28B OS=Gallus gallus OX=9031 GN=CCDC28B PE=4 SV=1 CANONICAL=A0A8V0Z8K4-1" }, "locus": { "chromosome": "23", "start_pos": 5529045, "end_pos": 5528133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042268.1", "url": "https://www.ensembl.org/id/ENSGALT00010042268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024773.1", "url": "https://www.ensembl.org/id/ENSGALP00010024773.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419647", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A3F9-1", "protein_name": "Coiled-coil domain containing 28B", "gene_name": "CCDC28B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRVGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEEEEEEEDGVAEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENTEPEEPSAV", "length": 200 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FEI4-1", "protein_name": "Coiled-coil domain-containing protein 28B isoform X1", "gene_name": "Ccdc28b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFKAPGRDSCVGVCRSNTSGSPAASGPGLRSNKHPMDDKKKKRSPKPCLAQPAQASGTLRRVPVPTSHSGSLALGLPHLPSPKQRTKFKRIGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEDEEDDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQPAS", "length": 235 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B8A4M8-1", "protein_name": "Coiled-coil domain-containing protein 28B", "gene_name": "ccdc28b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKRKKRSPKVSLPQPPPPPINPRKLTVLPASKSATFSLGLPQPPSPKPRGKYKRSVGAMGPSKEALAVPVVPPKNTRPHREKPRAPQPAGPSRVSQSSSPLQHTFLTDVSDVREMEGGLLNLLNDFHSGKLQAFGKVCSFEQLEHVREMQERLARLHFSLDSHVEELSEDQRKNASDRNLEHLLSNLEELSTSIQKLHLAENQDLPKTSNT", "length": 213 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R957-1", "protein_name": "Coiled coil domain containing 28B", "gene_name": "Ccdc28b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLLSPKQRAKFKRVGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQPAA", "length": 200 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CEG5-1", "protein_name": "Coiled-coil domain-containing protein 28B", "gene_name": "Ccdc28b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRAGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEDQPAA", "length": 200 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BUN5-1", "protein_name": "Coiled-coil domain-containing protein 28B", "gene_name": "CCDC28B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDKKKKRSPKPCLAQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRVGKEKCRPVLAGGGSGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDDEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQSAA", "length": 200 }, "evidence": [ { "id": "A0A8V0Z8K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z934-1", "uniprot_ac": "A0A8V0Z934", "uniprot_id": "A0A8V0Z934_CHICK", "mass": { "chemical_mass": 43035.0, "monoisotopic_mass": 43035.0 }, "refseq": {}, "gene_names": [ { "name": "WBP1L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934" } ] } ], "protein_names": [ { "name": "WW domain binding protein 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0Z934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z934", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WBP1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934", "locus": { "chromosome": "6", "start_pos": 24172843, "end_pos": 24122748, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018831", "url": "https://www.ensembl.org/id/ENSGALG00010018831" } ] } } ], "crossref": [ { "id": "A0A8V0Z934", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z934", "database": "AlphaFoldDB", "categories": [] }, { "id": "423867", "url": "https://www.ncbi.nlm.nih.gov/gene/423867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1L7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7H8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z829", "url": "https://www.orthodb.org/?gene=A0A8V0Z829", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z839", "url": "https://www.orthodb.org/?gene=A0A8V0Z839", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z934", "url": "https://www.orthodb.org/?gene=A0A8V0Z934", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZEZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF00", "url": "https://www.orthodb.org/?gene=A0A8V0ZF00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF05", "url": "https://www.orthodb.org/?gene=A0A8V0ZF05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16209", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16209", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16209:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16209:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z1L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z829", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z829", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z829-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z829-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z839", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z839", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z839-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z839-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z934", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSQPYCMGTPSAGFSLGAGRWWQCSGRTSGLRTAGIASGTAANCLVPGVGEAKTKGSFLSAEHALRCSEGCWPPRDGRGQLLVEGTPEKQRLLSVGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 397, "header": "tr|A0A8V0Z934-1|A0A8V0Z934_CHICK Isoform 1 of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0Z1L7-1", "sequence": { "sequence": "MAPTHLHQRRALTPAAQVDCTLSSARAVFLSFFTFLNCSPFPTQLLAKKTFLIQKEMLRTWRYCNVGLVDIIRAGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 374, "header": "tr|A0A8V0Z1L7-1|A0A8V0Z934_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24167939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045456.1", "url": "https://www.ensembl.org/id/ENSGALT00010045456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027118.1", "url": "https://www.ensembl.org/id/ENSGALP00010027118.1" } ] } }, { "isoform_ac": "A0A8V0Z7H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0Z7H8-1", "sequence": { "sequence": "MDSQHRSGHATRPAPSPGSGFSAQATGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 326, "header": "tr|A0A8V0Z7H8-1|A0A8V0Z7H8_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24166029, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045467.1", "url": "https://www.ensembl.org/id/ENSGALT00010045467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027125.1", "url": "https://www.ensembl.org/id/ENSGALP00010027125.1" } ] } }, { "isoform_ac": "A0A8V0Z829-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0Z829-1", "sequence": { "sequence": "MARRFRAAMALMLFQALPEGLPASVEPAQPALQLYPNFWLGHVTEPFMDSQHRSGHATRPAPSPGSGFSAQATGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 373, "header": "tr|A0A8V0Z829-1|A0A8V0Z829_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24122841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045460.1", "url": "https://www.ensembl.org/id/ENSGALT00010045460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027122.1", "url": "https://www.ensembl.org/id/ENSGALP00010027122.1" } ] } }, { "isoform_ac": "A0A8V0Z839-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0Z839-1", "sequence": { "sequence": "MTALPGLQDKETCMGVNNQSYICETGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 342, "header": "tr|A0A8V0Z839-1|A0A8V0Z839_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24143398, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045478.1", "url": "https://www.ensembl.org/id/ENSGALT00010045478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027132.1", "url": "https://www.ensembl.org/id/ENSGALP00010027132.1" } ] } }, { "isoform_ac": "A0A8V0Z934-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0Z934-1", "sequence": { "sequence": "MTSSQPYCMGTPSAGFSLGAGRWWQCSGRTSGLRTAGIASGTAANCLVPGVGEAKTKGSFLSAEHALRCSEGCWPPRDGRGQLLVEGTPEKQRLLSVGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 397, "header": "tr|A0A8V0Z934-1|A0A8V0Z934_CHICK Isoform 1 of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24150224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045491.1", "url": "https://www.ensembl.org/id/ENSGALT00010045491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027141.1", "url": "https://www.ensembl.org/id/ENSGALP00010027141.1" } ] } }, { "isoform_ac": "A0A8V0ZEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0ZEY2-1", "sequence": { "sequence": "LVVVEKALLLSELQSPAGTCRHPARRARPAASVPHRQRSSSASSPALPRGFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 349, "header": "tr|A0A8V0ZEY2-1|A0A8V0ZEY2_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24150957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045457.1", "url": "https://www.ensembl.org/id/ENSGALT00010045457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027119.1", "url": "https://www.ensembl.org/id/ENSGALP00010027119.1" } ] } }, { "isoform_ac": "A0A8V0ZEZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0ZEZ1-1", "sequence": { "sequence": "MLKLVQDKETCMGVNNQSYICETGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 340, "header": "tr|A0A8V0ZEZ1-1|A0A8V0ZEZ1_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24137023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045474.1", "url": "https://www.ensembl.org/id/ENSGALT00010045474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027129.1", "url": "https://www.ensembl.org/id/ENSGALP00010027129.1" } ] } }, { "isoform_ac": "A0A8V0ZEZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0ZEZ6-1", "sequence": { "sequence": "MGAGRGAGCPLGSRPGPQSGWGGGERGVGGMARRFRAAMALMLFQALPEGLPASVEPAQDKETCMGVNNQSYICETGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 393, "header": "tr|A0A8V0ZEZ6-1|A0A8V0ZEZ6_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24122751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045480.1", "url": "https://www.ensembl.org/id/ENSGALT00010045480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027134.1", "url": "https://www.ensembl.org/id/ENSGALP00010027134.1" } ] } }, { "isoform_ac": "A0A8V0ZF00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0ZF00-1", "sequence": { "sequence": "MARRFRAAMALMLFQALPEGLPASVEPAQFHWDNGVECPFWERRPLENCLTSEASREDKETCMGVNNQSYICETGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 391, "header": "tr|A0A8V0ZF00-1|A0A8V0ZF00_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24122841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045487.1", "url": "https://www.ensembl.org/id/ENSGALT00010045487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027139.1", "url": "https://www.ensembl.org/id/ENSGALP00010027139.1" } ] } }, { "isoform_ac": "A0A8V0ZF05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934/entry#A0A8V0ZF05-1", "sequence": { "sequence": "MGVNNQSYICETGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRTKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSALHQQCVPAGSSSTIPDTPRNLQPAQSSSAAPSGNNSSTDSTGPPGLGDPEPSTAALVERAVAKMQSVEPGGTSTGAELVERAGPEKDTECKEELLKGYSSESLEQSSAIPDAKDKTPGRQRRFTGDSGIEVCVCNRGHHDDDLKEFDGLINDALDGPLDFCDSCSGRPHGDEEEGLFNATEEQHREHSHHHLPRQPVCVLLNTINEQDSPNSRTNSSPS", "length": 329, "header": "tr|A0A8V0ZF05-1|A0A8V0ZF05_CHICK Computationally mapped isoform of WW domain binding protein 1 like OS=Gallus gallus OX=9031 GN=WBP1L PE=4 SV=1 CANONICAL=A0A8V0Z934-1" }, "locus": { "chromosome": "6", "start_pos": 24171232, "end_pos": 24159101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045497.1", "url": "https://www.ensembl.org/id/ENSGALT00010045497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027144.1", "url": "https://www.ensembl.org/id/ENSGALP00010027144.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z934", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "CXCL12-activated CXCR4 signaling pathway", "id": "GO:0038160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z934", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z934" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z915-1", "uniprot_ac": "A0A8V0Z915", "uniprot_id": "A0A8V0Z915_CHICK", "mass": { "chemical_mass": 61840.0, "monoisotopic_mass": 61840.0 }, "refseq": { "ac": "XP_046794083", "name": "endonuclease/exonuclease/phosphatase family domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794083" }, "gene_names": [ { "name": "EEPD1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ] }, { "name": "EEPD1", "type": "synonym", "evidence": [ { "id": "XP_046794083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794083" } ] } ], "protein_names": [ { "name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915/entry#names_and_taxonomy" } ] }, { "name": "endonuclease/exonuclease/phosphatase family domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_046794083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794083" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046794083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794083" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EEPD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915", "locus": { "chromosome": "2", "start_pos": 46713752, "end_pos": 46773458, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018832", "url": "https://www.ensembl.org/id/ENSGALG00010018832" } ] } } ], "crossref": [ { "id": "A0A8V0Z915", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z915", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420740", "url": "https://www.ncbi.nlm.nih.gov/gene/420740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420740", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420740", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLVPANT", "url": "https://omabrowser.org/oma/group/HLVPANT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1M2", "url": "https://www.orthodb.org/?gene=A0A8V0Z1M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z915", "url": "https://www.orthodb.org/?gene=A0A8V0Z915", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21180:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21180:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046794083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z915-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGNLGCHRSIPRDPADLCHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVAQNIVEYREYIGGFKKVEDLALVSGVGAAKLEQVKFEICVSSKGSSAQHSPSSLRKDPASEHHLSATKININTATPAQLMSIRGITEKIANSIVDYRKEHGPFKSIEDLVRMNCINSSFLDKIRHQIFAERSRPPSTNTNGGVNFTAKPHPSPTSLSLQSEDLDFPPGGPTQIISTRPSVEMFGGLRDGRPVLRVATWNLQSCSIEKANNPGVREVICMTLLENSIKLLAVQELLDREALEKFCMELNQPTLPNIRKWKGPRGCWKGVVSEKPSGQLPKGVEYCGFLWDTTAGIELKDASSQENVQTNGNGRHSYPHPYIAHFKVGMNDLTLVNLHLALAPAVGDNAGKNHDSHKLATFAQTLQETLKGEKDVIILGDFNQAADSSDHDILRKEKFHHLVPSNTFTNISTKNPQGSKSLDNMWISRSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASDHCPVLAEFYMEKDWNRKEVTRNGNGVTVERDSNTKHER", "length": 558, "header": "tr|A0A8V0Z915-1|A0A8V0Z915_CHICK Isoform 1 of Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Gallus gallus OX=9031 GN=EEPD1 PE=4 SV=1 CANONICAL=A0A8V0Z915-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915/entry#A0A8V0Z1M2-1", "sequence": { "sequence": "MGGNLGCHRSIPRDPADLCHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVAQNIVEYREYIGGFKKVEDLALVSGVGAAKLEQVKFEICVSSKGSSAQHSPSSLRKDPASEHHLSATKININTATPAQLMSIRGITEKIANSIVDYRKEHGPFKSIEDLVRMNCINSSFLDKIRHQIFAERSRPPSTNTNGGVNFTAKPHPSPTSLSLQSEDLDFPPGGPTQIISTRPSVEMFGGLRDGRPVLRVATWNLQSCSIEKANNPGVREVICMTLLENSIKLLAVQELLDREALEKGVEYCGFLWDTTAGIELKDASSQENVQTNGNGRHSYPHPYIAHFKVGMNDLTLVNLHLALAPAVGDNAGKNHDSHKLATFAQTLQETLKGEKDVIILGDFNQAADSSDHDILRKEKFHHLVPSNTFTNISTKNPQGSKSLDNMWISRSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASDHCPVLAEFYMEKDWNRKEVTRNGNGVTVERDSNTKHER", "length": 521, "header": "tr|A0A8V0Z1M2-1|A0A8V0Z915_CHICK Computationally mapped isoform of Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Gallus gallus OX=9031 GN=EEPD1 PE=4 SV=1 CANONICAL=A0A8V0Z915-1" }, "locus": { "chromosome": "2", "start_pos": 46773170, "end_pos": 46714055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045463.1", "url": "https://www.ensembl.org/id/ENSGALT00010045463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027123.1", "url": "https://www.ensembl.org/id/ENSGALP00010027123.1" } ] } }, { "isoform_ac": "A0A8V0Z915-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915/entry#A0A8V0Z915-1", "sequence": { "sequence": "MGGNLGCHRSIPRDPADLCHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVAQNIVEYREYIGGFKKVEDLALVSGVGAAKLEQVKFEICVSSKGSSAQHSPSSLRKDPASEHHLSATKININTATPAQLMSIRGITEKIANSIVDYRKEHGPFKSIEDLVRMNCINSSFLDKIRHQIFAERSRPPSTNTNGGVNFTAKPHPSPTSLSLQSEDLDFPPGGPTQIISTRPSVEMFGGLRDGRPVLRVATWNLQSCSIEKANNPGVREVICMTLLENSIKLLAVQELLDREALEKFCMELNQPTLPNIRKWKGPRGCWKGVVSEKPSGQLPKGVEYCGFLWDTTAGIELKDASSQENVQTNGNGRHSYPHPYIAHFKVGMNDLTLVNLHLALAPAVGDNAGKNHDSHKLATFAQTLQETLKGEKDVIILGDFNQAADSSDHDILRKEKFHHLVPSNTFTNISTKNPQGSKSLDNMWISRSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASDHCPVLAEFYMEKDWNRKEVTRNGNGVTVERDSNTKHER", "length": 558, "header": "tr|A0A8V0Z915-1|A0A8V0Z915_CHICK Isoform 1 of Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Gallus gallus OX=9031 GN=EEPD1 PE=4 SV=1 CANONICAL=A0A8V0Z915-1" }, "locus": { "chromosome": "2", "start_pos": 46773170, "end_pos": 46714055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045459.1", "url": "https://www.ensembl.org/id/ENSGALT00010045459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027121.1", "url": "https://www.ensembl.org/id/ENSGALP00010027121.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420740", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420740", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQI4-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "EEPD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATSVPLTPRVNINTATPAQLMSVRGLTEKMAISIVDYRREHGPFRSVEDLVRMGGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCTELNQPILPNIRKWKGPRGCWKVVVSETPSTQLPKGAGFAGFLWDVTAGVELRDAAWQESSPGNGHGKPAGPSPYLARFKVGSHDLTLVNLHLAALTLPGGENPSKNHSDGHRWASFTQTLQESLKGEKDVIVLGDFGQGPDSSDYDILRKEKFHPLIPAHTFTNISTKNPQGSKTLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDGSRKEGPRNSSGVTLEPSEANIKHER", "length": 569 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HTJ3-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "Eepd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHNRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGNSAQHSPSSLRRDLLAEQQPHHLATSVPLTPRVNINTATLAQLMSIRGLTEKMAVSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISMRPSVEAFGGMRDGRPVFRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDKEALEKFCTELNQPILPNIRKWKGSRGCWRSVIAEKPSSQLQKGACYSGFLWDTAASVELRDIPGQESSPSNGHGKAVGPSPFLARFKVGSNDLTLVNLQLTALALPGAENPSKNHGDGHRLLNFALTLQETLKGEKDVVILGDFGQGPDSSDCDILRREKFHHVIPAHTFTNISTRNPQGSKSVDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAELYMEKDWSKKEVPRNGNGVTLERSEANIKHER", "length": 569 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3MHJ7-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "EEPD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLMAEQQPHHLATAAAVPLTPRVNINTATPAQLMSVRGLTEKMAVSIVDYRREHGPFRSVEDLVRMGGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCVELNQPILPNIRKWKGPRGCWKAVVSETPSTQLQKGAGFAGFLWDTAAGVELRDAAWQESSPGNGHGKPVGPSPYLARFKVGSHDLTLVNLHLATLTLPGGENLSKNHSDSHRWASFTQTLQETLKGEKDVIVLGDFGQGPDSSDYDILRKEKFHHLIPAHTFTNISTKNPQGSKALDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDWTRKEGPRSGNGLTLERSEANIKHER", "length": 571 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TGW2-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "Eepd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHNRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGNSAQHSPSSLRRDLLAEQQPHHLTTTVPLTPRVNINTATLAQLMSVRGLSEKMALSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISMRPSVEAFGGMRDGRPVFRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDKEALEKFCTELNQPILPNIRKWKGSRGCWRSIVAEKPSNQLQKGPCYSGFLWDTAANVELRDIPGRESSPSNGHAKAVGPSPFLARFKVGSNDLTLVNLQLTALALPGAENSSKNHSDGHRLLNFALTLQETLKGEKDVVILGDFGQGPDSNDYDILRREKFHHLVPAHTFTNISTRNPQGSKSVDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAELYMEKDWSKKEVPRNGNGVTLEPSEANIKHER", "length": 569 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XI74-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "Eepd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGNSAQHSPSSLRRDLLAEQQPHHLATTVPLTPRVNINTATLAQLMSVRGLSEKMAVSIVDYRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISMRPSVEAFGGMRDGRPVFRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDKEALEKFCTELNQPILPNIRKWKGPRGCWRSIVAEKPSSQLQKGPCYSGFLWDTAANVELRDIPGQESSPSNGHAKTVGPSPFLARFKVGSNDLTLVNLQLTALALPGVENSSKNHSDGHRLLNFALTLQETLKGEKDVVILGDFGQGPDSSDYDILRREKFHHLIPAHTFTNISTRNPQGSKSVDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAELYMEKDWSKKEVPRNGNGVTLEPSEANVKHER", "length": 569 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L9B9-1", "protein_name": "Endonuclease/exonuclease/phosphatase family domain-containing protein 1", "gene_name": "EEPD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDWSKKDAPRNGSGVALERSEANIKHER", "length": 569 }, "evidence": [ { "id": "A0A8V0Z915", "url": "https://omabrowser.org/oma/group/A0A8V0Z915/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "pmid": "" }, { "name": "positive regulation of cholesterol efflux", "id": "GO:0010875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z915", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z915" }, { "id": "SM00278", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helix-hairpin-helix DNA-binding motif class 1", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 67, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 511, "end_pos": 513 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z844-1", "uniprot_ac": "A0A8V0Z844", "uniprot_id": "A0A8V0Z844_CHICK", "mass": { "chemical_mass": 46778.0, "monoisotopic_mass": 46778.0 }, "refseq": { "ac": "NP_001264488", "name": "ribosomal protein uL3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264488" }, "gene_names": [ { "name": "RPL3L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ] }, { "name": "RPL3L", "type": "synonym", "evidence": [ { "id": "NP_001264488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264488" } ] } ], "protein_names": [ { "name": "60S ribosomal protein L3-like", "type": "recommended", "evidence": [ { "id": "A0A8V0Z844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein uL3-like", "type": "synonym", "evidence": [ { "id": "NP_001264488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264488" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX935844.1, BX929329.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04013384 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001264488.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264488" } ] }, { "annotation": "Heart- and skeletal muscle-specific component of the ribosome, which regulates muscle function. Component of the large ribosomal subunit in striated muscle cells: replaces the RPL3 paralog in the ribosome in these cells. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Inhibits myotube growth and muscle function.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z939", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z939#function" }, { "database": "UniProtKB", "id": "ARBA00055008", "url": "https://www.uniprot.org/uniprotkb/ARBA00055008#function" }, { "database": "UniProtKB", "id": "A0A8V0Z1P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J4#function" }, { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844", "locus": { "chromosome": "14", "start_pos": 6135330, "end_pos": 6144201, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018839", "url": "https://www.ensembl.org/id/ENSGALG00010018839" } ] } } ], "crossref": [ { "id": "A0A8V0Z844", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z844", "database": "AlphaFoldDB", "categories": [] }, { "id": "416542", "url": "https://www.ncbi.nlm.nih.gov/gene/416542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416542", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z1P2", "url": "https://www.orthodb.org/?gene=A0A8V0Z1P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7J4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z844", "url": "https://www.orthodb.org/?gene=A0A8V0Z844", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z939", "url": "https://www.orthodb.org/?gene=A0A8V0Z939", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11363:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11363:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z844-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z939", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z939", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z939-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z939-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHRKFSAPRHGHLGFLPHKRSRRHRGKVKTWPKDDPSKPVHLTAFMGYKAGMTHTLREVHRPGLRISKREEVEAVTIIETPPMVVVGVVGYIDTPKGLRNFKTVFAEHISDECRRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFAAMKKYCKVIRVIMHTQMKLLPLRQKKAHVMEIQLNGGTVAEKVDWVRERLEKQISVHSVFSQNEMIDVIGVTKGHGMKGVTSRWHSKKLPRKTHKGLRKVACIGAWHPARVGYSVARAGQKGYHHRTELNKKIFRIGHGIHVEDGKVVKNNASTNYDVTEKTITPLGGFPHYGEVNNDFLMLKGCVVGPKKRVLTLRKSLLVHTRRRAHEAIELKFIDTTSKFGHGCFQTAQEKRAFMGPQKKHLVKVKPGAQEEL", "length": 407, "header": "tr|A0A8V0Z844-1|A0A8V0Z844_CHICK Isoform 1 of 60S ribosomal protein L3-like OS=Gallus gallus OX=9031 GN=RPL3L PE=3 SV=1 CANONICAL=A0A8V0Z844-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844/entry#A0A8V0Z1P2-1", "sequence": { "sequence": "MAAPHTAPAAADAESHRKFSAPRHGHLGFLPHKRSRRHRGKVKTWPKDDPSKPVHLTAFMGYKAGMTHTLREVHRPGLRISKREEVEAVTIIETPPMVVVGVVGYIDTPKGLRNFKTVFAEHISDECRRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFAAMKKYCKVIRVIMHTQMKLLPLRQKKAHVMEIQLNGGTVAEKVDWVRERLEKQISVHSVFSQNEMIDVIGVTKGHGMKGVTSRWHSKKLPRKTHKGLRKVACIGAWHPARVGYSVARAGQKGYHHRTELNKKIFRIGHGIHVEDGKVVKNNASTNYDVTEKTITPLVGGNRAETGPGCRSLCQRSNSLAGHSCIGNDLNSTEGIQSVWLKCSGDTGWLF", "length": 383, "header": "tr|A0A8V0Z1P2-1|A0A8V0Z844_CHICK Computationally mapped isoform of 60S ribosomal protein L3-like OS=Gallus gallus OX=9031 GN=RPL3L PE=3 SV=1 CANONICAL=A0A8V0Z844-1" }, "locus": { "chromosome": "14", "start_pos": 6143581, "end_pos": 6137717, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045496.1", "url": "https://www.ensembl.org/id/ENSGALT00010045496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027143.1", "url": "https://www.ensembl.org/id/ENSGALP00010027143.1" } ] } }, { "isoform_ac": "A0A8V0Z7J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844/entry#A0A8V0Z7J4-1", "sequence": { "sequence": "MSHRKFSAPRHGHLGFLPHKRSRRHRGKVKTWPKDDPSKPVHLTAFMGYKAGMTHTLREVHRPGLRISKREEVEAVTIIETPPMVVVGVVGYIDTPKGLRNFKTVFAEHISDECRRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFAAMKKYCKVIRVIMHTQMKLLPLRQKKAHVMEIQLNGGTVAEKVDWVRERLEKQISVHSVFSQNEMIDVIGVTKGHGMKGVTSRWHSKKLPRKTHKGLRKVACIGAWHPARVGYSVARAGQKGYHHRTELNKKIFRIGHGIHVEDGKVVKNNASTNYDVTEKTITPLGGFPHYGEVNNDFLMLKGCVVGPKKRVLTLRKGPQKKHLVKVKPGAQEEL", "length": 367, "header": "tr|A0A8V0Z7J4-1|A0A8V0Z7J4_CHICK Computationally mapped isoform of 60S ribosomal protein L3-like OS=Gallus gallus OX=9031 GN=RPL3L PE=3 SV=1 CANONICAL=A0A8V0Z844-1" }, "locus": { "chromosome": "14", "start_pos": 6142671, "end_pos": 6135394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045488.1", "url": "https://www.ensembl.org/id/ENSGALT00010045488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027140.1", "url": "https://www.ensembl.org/id/ENSGALP00010027140.1" } ] } }, { "isoform_ac": "A0A8V0Z844-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844/entry#A0A8V0Z844-1", "sequence": { "sequence": "MSHRKFSAPRHGHLGFLPHKRSRRHRGKVKTWPKDDPSKPVHLTAFMGYKAGMTHTLREVHRPGLRISKREEVEAVTIIETPPMVVVGVVGYIDTPKGLRNFKTVFAEHISDECRRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFAAMKKYCKVIRVIMHTQMKLLPLRQKKAHVMEIQLNGGTVAEKVDWVRERLEKQISVHSVFSQNEMIDVIGVTKGHGMKGVTSRWHSKKLPRKTHKGLRKVACIGAWHPARVGYSVARAGQKGYHHRTELNKKIFRIGHGIHVEDGKVVKNNASTNYDVTEKTITPLGGFPHYGEVNNDFLMLKGCVVGPKKRVLTLRKSLLVHTRRRAHEAIELKFIDTTSKFGHGCFQTAQEKRAFMGPQKKHLVKVKPGAQEEL", "length": 407, "header": "tr|A0A8V0Z844-1|A0A8V0Z844_CHICK Isoform 1 of 60S ribosomal protein L3-like OS=Gallus gallus OX=9031 GN=RPL3L PE=3 SV=1 CANONICAL=A0A8V0Z844-1" }, "locus": { "chromosome": "14", "start_pos": 6142671, "end_pos": 6135394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045484.1", "url": "https://www.ensembl.org/id/ENSGALT00010045484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027137.1", "url": "https://www.ensembl.org/id/ENSGALP00010027137.1" } ] } }, { "isoform_ac": "A0A8V0Z939-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844/entry#A0A8V0Z939-1", "sequence": { "sequence": "MAAPHTAPAAADAESHRKFSAPRHGHLGFLPHKRSRRHRGKVKTWPKDDPSKPVHLTAFMGYKAGMTHTLREVHRPGLRISKREEVEAVTIIETPPMVVVGVVGYIDTPKGLRNFKTVFAEHISDECRRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFAAMKKYCKVIRVIMHTQMKLLPLRQKKAHVMEIQLNGGTVAEKVDWVRERLEKQISVHSVFSQNEMIDVIGVTKGHGMKGVTSRWHSKKLPRKTHKGLRKVACIGAWHPARVGYSVARAGQKGYHHRTELNKKIFRIGHGIHVEDGKVVKNNASTNYDVTEKTITPLGGFPHYGEVNNDFLMLKGCVVGPKKRVLTLRKSLLVHTRRRAHEAIELKFIDTTSKFGHGCFQTAQEKRAFMGPQKKHLVKVKPGAQEEL", "length": 420, "header": "tr|A0A8V0Z939-1|A0A8V0Z939_CHICK Computationally mapped isoform of 60S ribosomal protein L3-like OS=Gallus gallus OX=9031 GN=RPL3L PE=3 SV=1 CANONICAL=A0A8V0Z844-1" }, "locus": { "chromosome": "14", "start_pos": 6143581, "end_pos": 6135394, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045501.1", "url": "https://www.ensembl.org/id/ENSGALT00010045501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027146.1", "url": "https://www.ensembl.org/id/ENSGALP00010027146.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416542", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" }, { "name": "regulation of striated muscle tissue development", "id": "GO:0016202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" }, { "name": "negative regulation of myotube differentiation", "id": "GO:0010832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010832", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z844" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z844", "url": 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z858-1", "uniprot_ac": "A0A8V0Z858", "uniprot_id": "A0A8V0Z858_CHICK", "mass": { "chemical_mass": 39182.0, "monoisotopic_mass": 39182.0 }, "refseq": { "ac": "XP_001235056", "name": "cell growth regulator with RING finger domain protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235056" }, "gene_names": [ { "name": "CGRRF1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ] }, { "name": "CGRRF1", "type": "synonym", "evidence": [ { "id": "XP_001235056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235056" } ] } ], "protein_names": [ { "name": "Cell growth regulator with RING finger domain protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858/entry#names_and_taxonomy" } ] }, { "name": "Cell growth regulatory gene 19 protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858/entry#names_and_taxonomy" } ] }, { "name": "cell growth regulator with RING finger domain protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001235056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235056" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001235056.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001235056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235056" } ] }, { "annotation": "Able to inhibit growth in several cell lines.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858#function" }, { "database": "UniProtKB", "id": "ARBA00054111", "url": "https://www.uniprot.org/uniprotkb/ARBA00054111#function" }, { "database": "UniProtKB", "id": "A0A8V0Z1P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CGRRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858", "locus": { "chromosome": "5", "start_pos": 56035121, "end_pos": 56047347, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018847", "url": "https://www.ensembl.org/id/ENSGALG00010018847" } ] } } ], "crossref": [ { "id": "A0A8V0Z858", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z858", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776040", "url": "https://www.ncbi.nlm.nih.gov/gene/776040", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776040", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776040", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYCQLPK", "url": "https://omabrowser.org/oma/group/IYCQLPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1P8", "url": "https://www.orthodb.org/?gene=A0A8V0Z1P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z858", "url": "https://www.orthodb.org/?gene=A0A8V0Z858", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15379:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15379:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001235056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVFLVTLYEYSPLFYITVVFVCFLVTSGLVLGWFGLGVPVILRNSEGTESSTRVLKKRMRQVKNPFGLEISHPDTASVTRGITLIPDCLEDCVLTCYWGCNVQKLHEALQKHVYCFRINTPQALEDALYDEYLYRQQYFIKKNDKEEKYCQLPEDAQVVDFGPVPRLCYPLIALLTLADEEDREIYDIISMVSVIHVPDESYRLSCRILYQYLLLAQGQYHDLKQLFMSANSTTPPSCGTSPDERSTDRSLLEKAGLAEDEPELHEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCIKYFQQCPMCRQFVQESFPLCSKKEQDEDESTQILQDVHPGRVF", "length": 342, "header": "tr|A0A8V0Z858-1|A0A8V0Z858_CHICK Isoform 1 of Cell growth regulator with RING finger domain protein 1 OS=Gallus gallus OX=9031 GN=CGRRF1 PE=4 SV=1 CANONICAL=A0A8V0Z858-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858/entry#A0A8V0Z1P8-1", "sequence": { "sequence": "MRQVKNPFGLEISHPDTASVTRGITLIPDCLEDCVLTCYWGCNVQKLHEALQKHVYCFRINTPQALEDALYDEYLYRQQYFIKKNDKEEKYCQLPEDAQVVDFGPVPRLCYPLIALLTLADEEDREIYDIISMVSVIHVPDESYRLSCRILYQYLLLAQGQYHDLKLFMSANSTTPPSCGTSPDERSTDRSLLEKAGLAEDEPELHEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCIKYFQQCPMCRQFVQESFPLCSKKEQDEDESTQILQDVHPGRVF", "length": 281, "header": "tr|A0A8V0Z1P8-1|A0A8V0Z858_CHICK Computationally mapped isoform of Cell growth regulator with RING finger domain protein 1 OS=Gallus gallus OX=9031 GN=CGRRF1 PE=4 SV=1 CANONICAL=A0A8V0Z858-1" }, "locus": { "chromosome": "5", "start_pos": 56042560, "end_pos": 56037616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045512.1", "url": "https://www.ensembl.org/id/ENSGALT00010045512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027148.1", "url": "https://www.ensembl.org/id/ENSGALP00010027148.1" } ] } }, { "isoform_ac": "A0A8V0Z858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858/entry#A0A8V0Z858-1", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYITVVFVCFLVTSGLVLGWFGLGVPVILRNSEGTESSTRVLKKRMRQVKNPFGLEISHPDTASVTRGITLIPDCLEDCVLTCYWGCNVQKLHEALQKHVYCFRINTPQALEDALYDEYLYRQQYFIKKNDKEEKYCQLPEDAQVVDFGPVPRLCYPLIALLTLADEEDREIYDIISMVSVIHVPDESYRLSCRILYQYLLLAQGQYHDLKQLFMSANSTTPPSCGTSPDERSTDRSLLEKAGLAEDEPELHEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCIKYFQQCPMCRQFVQESFPLCSKKEQDEDESTQILQDVHPGRVF", "length": 342, "header": "tr|A0A8V0Z858-1|A0A8V0Z858_CHICK Isoform 1 of Cell growth regulator with RING finger domain protein 1 OS=Gallus gallus OX=9031 GN=CGRRF1 PE=4 SV=1 CANONICAL=A0A8V0Z858-1" }, "locus": { "chromosome": "5", "start_pos": 56047260, "end_pos": 56037616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045520.1", "url": "https://www.ensembl.org/id/ENSGALT00010045520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027152.1", "url": "https://www.ensembl.org/id/ENSGALP00010027152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776040", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776040", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MGK4-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEEIQFSTRAFKKQMRQVKNPFGLEITNSSSASLAAGVTLTTDCLEDSRLTCFWGCSVQRLYEALQKHRYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPRDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLLLAQGQFYDLKQLFMSANSSPSPSSKPSPADRNAEQSLLEKAGLAGSEVEPVEESSKDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEPDKDMLETS", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BIW8-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHFYCFRISTPRALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADKDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEEKNTDRSLLEKAGLSESEVEPPEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LCB8-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFNTRVFKKQMRQVKNPFGLEITNPSSASITTGITLRTDCLEDSLLTCYWGCSVQRLYEALQKHFYCFRISTPRALDDALYSEYLYQEQYFIKKDSKEEIYCQLPRENKIEDFGMVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNSTPSSNSSPEGKNTDQSLMEKAGLSESEVEPLEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKLKSL", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97587-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIATTGLVLGWLGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGVTLTTDCLEDSRLTCYWGCSVQKLYEALQKHVYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSSTGVEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSATPSRDQSPADGSVEHSLLEKAGLAGAEVDPVEESSKDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEADKDILETS", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BMJ7-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "Cgrrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGMALRTDCLEDSRLTCYWGCSVQKLYEALQKHAYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSPPPSNDESPEDRSVEQSLLEKVGLAGNDGDPVEESSRDCVVCQNGGVNWVLLPCRHACLCDSCVRYFKQCPMCRQFVQESFALCGQKEPDKDLLETS", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99675-1", "protein_name": "Cell growth regulator with RING finger domain protein 1", "gene_name": "CGRRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHVYCFRISTPQALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDRTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKPKTL", "length": 332 }, "evidence": [ { "id": "A0A8V0Z858", "url": "https://omabrowser.org/oma/group/A0A8V0Z858/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z858" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 309, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8U7-1", "uniprot_ac": "A0A8V0Z8U7", "uniprot_id": "A0A8V0Z8U7_CHICK", "mass": { "chemical_mass": 206560.0, "monoisotopic_mass": 206560.0 }, "refseq": {}, "gene_names": [ { "name": "RAI1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7" } ] } ], "protein_names": [ { "name": "Retinoic acid induced 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7", "locus": { "chromosome": "14", "start_pos": 4914027, "end_pos": 4851569, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017528", "url": "https://www.ensembl.org/id/ENSGALG00010017528" } ] } } ], "crossref": [ { "id": "427664", "url": "https://www.ncbi.nlm.nih.gov/gene/427664", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427664", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427664", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQSQSYS", "url": "https://omabrowser.org/oma/group/HQSQSYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1R8", "url": "https://www.orthodb.org/?gene=A0A8V0Z1R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8U7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8U7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14955:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14955:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z1R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSFRERCGFHGNQQSYQPTSQDTSRLENYRHQSQAGPNCERQRLVAKEYYSQQQLPYTGYENSAAEKYHRGNKQLAGQQLQGRPAFSNYAVQENSPYPARYSGDESLQAWGGQPPALPKYEDGLMKKTSPAAGGRPYHEPAAAPLPFRTHFPQQQPQQPPTLPYPKLQRQKLPNDVSSPMPFSQSPHFGQHSQSFPASSTYSSVPGGSQPAHSYKSCTAPSGQPPLERPLSSAASLAPGPRVPNLHGYQPNRMGYEQPPQPPPQPPPPPQPPQPPQPPQPQPQPLQGRHHAPESLHYQNLAKYQHYNQAGQTYCQGDAPPVRTPEQYYQTFSPSASHSPARSVGRSPSYSSTPSPLMPNLENFQYSQQPLNAGAFPAGIADHSHFMPLLNPSPTDGTSPDAQSGNCKNLPKEKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKSAVPQKKGIKTPARTPEQLKGQHCSPESSTYSAEQVGTPLSDPLSTPQSVHAETQDADYLSGSEDQLERSFLYCNQSRSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSIHASLPLDTFTKYVTNERDCPRLLLSALSQEELASEIIVLQDAINEKEDKAWANSPMLSKESTKSPFQLENHRPCLDSMVKGSWPSQGDSSTLTEPLKLDKASGGSTGKDFGEEVYEGPQVEFAATETKDTLKDADPLAFNSKPSIPAATSSAGASGFSCYSNTTANSVGSENAMEHFEWPEENLGEACLRWKELGSGLQASDLPKGLFPSKMGGSCKEKKNACSLDLCDGEQPAKSETTRDFGQQAMEEEEEETLTYDEATKVDSERWLQDTRHCCTAGDFGEIPMISSPELKESDLEVEEYSSLCELAGTEQKSVPYAASPPKPPEIPAVLSASEVPMSAEETVSTVEKESSVPSARLSGQSIILLGPAVGTETKVKSWFKSSLPHIQPEEESGGVEKSHPEAVDSEPVLSLGVKKQPTPENALVKTEPVSRGKNLRNKRIHCRLPEEDSAGNAVPSPFSELPALCVGPDGQGEMLSKNVHSQTPRFAAEGLPARMCTRSFTALAEPRAPAPLEGLKAPTHQEKLGKKPACGVKQRVAFKARKRSGRPAPKVIQSAGGDAAITVPSLVPAEEVVGPGPTDGDVADGGERDQRSMILRSRTKTQEVFYTKRRRGKRAADVRLKNCKAPKKLISNNHLPPAFKLTPPGSPHKEGKVGTRMKLPKAGPGVGGKMSERPLHSLKRKSTFISPIPAKKRNLVLRSNSGGVKEEKPEGPHSLFKKMPVAKKVKAKLPPKSPGEGVPKPPPVKEAPDVCIKITSRAAFQEATKTKVLPPRKGRGLKLEAIVQKITSPNLKKFTCKTAAAATVAATYGTSLSVAGAERERAVKHGGVALAVGDARLPKPAAAQKAPTAPSAEQLCRNPHGRALKGKPGSGKKLSADGSQSEGCTQAAGTQPGSAVAAKNMALLPKKRNRKGKAAALGMAKAPLGPALPLPPRERAAGPGGGDEGKKPKSEEKEAAGGEGPAAGGAARGAKPRANHANYNGYSKRQRKRLGHGKAKAVPVRCKSRGKRRRPAQQAPLPDPAEPEIRLKYISCKRLRADSRAPPFAPYIHVERRGDFTTFCTVINSPSDEARLQRGPSGSVPRPRAALPASSAMHLGPVVSKALSAACLVCCLCRSPANYKDLGDLCGPYYPEDCLPKKKSRLKEKARAEGEEGGAAERPRGAAESGWVAGGRAGRPEGAAEPGKPSVLRSSPRGVFRRLQSCYCCDERTEGEEAAEKPRRHECTKAESPPQPEPAGDTQEHWLHEACAIWTAGVFLVAGKLYGLQEAVKAAADLVRARPAAPHGVGPPGAGVAAGPSPRWWRMVQPWVSLLGRDVGTLLARSLQALTPPEGMDGVHWEETPGPTSQWIHRACCIPD", "length": 1923, "header": "tr|A0A8V0Z8U7-1|A0A8V0Z8U7_CHICK Isoform 1 of Retinoic acid induced 1 OS=Gallus gallus OX=9031 GN=RAI1 PE=4 SV=1 CANONICAL=A0A8V0Z8U7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7/entry#A0A8V0Z1R8-1", "sequence": { "sequence": "MQSFRERCGFHGNQQSYQPTSQDTSRLENYRHQSQAGPNCERQRLVAKEYYSQQQLPYTGYENSAAEKYHRGNKQLAGQQLQGRPAFSNYAVQENSPYPARYSGDESLQAWGGQPPALPKYEDGLMKKTSPAAGGRPYHEPAAAPLPFRTHFPQQQPQQPPTLPYPKLQRQKLPNDVSSPMPFSQSPHFGQHSQSFPASSTYSSVPGGSQPAHSYKSCTAPSGQPPLERPLSSAASLAPGPRVPNLHGYQPNRMGYEQPPQPPPQPPPPPQPPQPPQPPQPQPQPLQGRHHAPESLHYQNLAKYQHYNQAGQTYCQGDAPPVRTPEQYYQTFSPSASHSPARSVGRSPSYSSTPSPLMPNLENFQYSQQPLNAGAFPAGIADHSHFMPLLNPSPTDGTSPDAQSGNCKNLPKEKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKSAVPQKKGIKTPARTPEQLKGQHCSPESSTYSAEQVGTPLSDPLSTPQSVHAETQDADYLSGSEDQLERSFLYCNQSRSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSIHASLPLDTFTKYVTNERDCPRLLLSALSQEELASEIIVLQDAINEKEDKAWANSPMLSKESTKSPFQLENHRPCLDSMVKGSWPSQGDSSTLTEPLKLDKASGGSTGKDFGEEVYEGPQVEFAATETKDTLKDADPLAFNSKPSIPAATSSAGASGFSCYSNTTANSVGSENAMEHFEWPEENLGEACLRWKELGSGLQASDLPKGLFPSKMGGSCKEKKNACSLDLCDGEQPAKSETTRDFGQQAMEEEEEETLTYDEATKVDSERWLQDTRHCCTAGDFGEIPMISSPELKESDLEVEEYSSLCELAGTEQKSVPYAASPPKPPEIPAVLSASEVPMSAEETVSTVEKESSVPSARLSGQSIILLGPAVGTETKVKSWFKSSLPHIQPEEESGGVEKSHPEAVDSEPVLSLGVKKQPTPENALVKTEPVSRGKNLRNKRIHCRLPEEDSAGNAVPSPFSELPALCVGPDGQGEMLSKNVHSQTPRFAAEGLPARMCTRSFTALAEPRAPAPLEGLKAPTHQEKLGKKPACGVKQRVAFKARKRSGRPAPKVIQSAGGDAAITVPSLVPAEEVVGPGPTDGDVADGGERDQRSMILRSRTKTQEVFYTKRRRGKRAADVRLKNCKAPKKLISNNHLPPAFKLTPPGSPHKEGKVGTRMKLPKAGPGVGGKMSERPLHSLKRKSTFISPIPAKKRNLVLRSNSGGVKEEKPEGPHSLFKKMPVAKKVKAKLPPKSPGEGVPKPPPVKEAPDVCIKITSRAAFQEATKTKVLPPRKGRGLKLEAIVQKITSPNLKKFTCKTAAAATVAATYGTSLSVAGAERERAVKHGGVALAVGDARLPKPAAAQKAPTAPSAEQLCRNPHGRALKGKPGSGKKLSADGSQSEGCTQAAGTQPGSAVAAKNMALLPKKRNRKGKAAALGMAKAPLGPALPLPPRERAAGPGGGDEGKKPKSEEKEAAGGEGPAAGGAARGAKPRANHANYNGYSKRQRKRLGHGKAKAVPVRCKSRGKRRRPAQQAPLPDPAEPEIRLKYISCKRLRADSRAPPFAPYIHVERRGDFTTFCTVINSPSDEARLQRGPSGSVPRPRAALPASSAMHLGPVVSKALSAACLVCCLCRSPANYKDLGDLCGPYYPEDCLPKKKSRLKEKARAEGEEGGAAERPRGAAESGWVAGGRAGRPEGAAEPGKPSVLRSSPRGVFRRLQSCYCCDERTEGEEAAEKPRRHECTKAESPPQPEPAGDTQEHWLHEACAIWTAGVFLVAGKLYGLQEAVKAAADLKCSSCQQAGATVGCCQKGCPHTYHYACAVDTGCLLTEESFSLRCPKHKRQPV", "length": 1893, "header": "tr|A0A8V0Z1R8-1|A0A8V0Z8U7_CHICK Computationally mapped isoform of Retinoic acid induced 1 OS=Gallus gallus OX=9031 GN=RAI1 PE=4 SV=1 CANONICAL=A0A8V0Z8U7-1" }, "locus": { "chromosome": "14", "start_pos": 4913023, "end_pos": 4905604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042366.1", "url": "https://www.ensembl.org/id/ENSGALT00010042366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024856.1", "url": "https://www.ensembl.org/id/ENSGALP00010024856.1" } ] } }, { "isoform_ac": "A0A8V0Z8U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U7/entry#A0A8V0Z8U7-1", "sequence": { "sequence": "MQSFRERCGFHGNQQSYQPTSQDTSRLENYRHQSQAGPNCERQRLVAKEYYSQQQLPYTGYENSAAEKYHRGNKQLAGQQLQGRPAFSNYAVQENSPYPARYSGDESLQAWGGQPPALPKYEDGLMKKTSPAAGGRPYHEPAAAPLPFRTHFPQQQPQQPPTLPYPKLQRQKLPNDVSSPMPFSQSPHFGQHSQSFPASSTYSSVPGGSQPAHSYKSCTAPSGQPPLERPLSSAASLAPGPRVPNLHGYQPNRMGYEQPPQPPPQPPPPPQPPQPPQPPQPQPQPLQGRHHAPESLHYQNLAKYQHYNQAGQTYCQGDAPPVRTPEQYYQTFSPSASHSPARSVGRSPSYSSTPSPLMPNLENFQYSQQPLNAGAFPAGIADHSHFMPLLNPSPTDGTSPDAQSGNCKNLPKEKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKSAVPQKKGIKTPARTPEQLKGQHCSPESSTYSAEQVGTPLSDPLSTPQSVHAETQDADYLSGSEDQLERSFLYCNQSRSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSIHASLPLDTFTKYVTNERDCPRLLLSALSQEELASEIIVLQDAINEKEDKAWANSPMLSKESTKSPFQLENHRPCLDSMVKGSWPSQGDSSTLTEPLKLDKASGGSTGKDFGEEVYEGPQVEFAATETKDTLKDADPLAFNSKPSIPAATSSAGASGFSCYSNTTANSVGSENAMEHFEWPEENLGEACLRWKELGSGLQASDLPKGLFPSKMGGSCKEKKNACSLDLCDGEQPAKSETTRDFGQQAMEEEEEETLTYDEATKVDSERWLQDTRHCCTAGDFGEIPMISSPELKESDLEVEEYSSLCELAGTEQKSVPYAASPPKPPEIPAVLSASEVPMSAEETVSTVEKESSVPSARLSGQSIILLGPAVGTETKVKSWFKSSLPHIQPEEESGGVEKSHPEAVDSEPVLSLGVKKQPTPENALVKTEPVSRGKNLRNKRIHCRLPEEDSAGNAVPSPFSELPALCVGPDGQGEMLSKNVHSQTPRFAAEGLPARMCTRSFTALAEPRAPAPLEGLKAPTHQEKLGKKPACGVKQRVAFKARKRSGRPAPKVIQSAGGDAAITVPSLVPAEEVVGPGPTDGDVADGGERDQRSMILRSRTKTQEVFYTKRRRGKRAADVRLKNCKAPKKLISNNHLPPAFKLTPPGSPHKEGKVGTRMKLPKAGPGVGGKMSERPLHSLKRKSTFISPIPAKKRNLVLRSNSGGVKEEKPEGPHSLFKKMPVAKKVKAKLPPKSPGEGVPKPPPVKEAPDVCIKITSRAAFQEATKTKVLPPRKGRGLKLEAIVQKITSPNLKKFTCKTAAAATVAATYGTSLSVAGAERERAVKHGGVALAVGDARLPKPAAAQKAPTAPSAEQLCRNPHGRALKGKPGSGKKLSADGSQSEGCTQAAGTQPGSAVAAKNMALLPKKRNRKGKAAALGMAKAPLGPALPLPPRERAAGPGGGDEGKKPKSEEKEAAGGEGPAAGGAARGAKPRANHANYNGYSKRQRKRLGHGKAKAVPVRCKSRGKRRRPAQQAPLPDPAEPEIRLKYISCKRLRADSRAPPFAPYIHVERRGDFTTFCTVINSPSDEARLQRGPSGSVPRPRAALPASSAMHLGPVVSKALSAACLVCCLCRSPANYKDLGDLCGPYYPEDCLPKKKSRLKEKARAEGEEGGAAERPRGAAESGWVAGGRAGRPEGAAEPGKPSVLRSSPRGVFRRLQSCYCCDERTEGEEAAEKPRRHECTKAESPPQPEPAGDTQEHWLHEACAIWTAGVFLVAGKLYGLQEAVKAAADLVRARPAAPHGVGPPGAGVAAGPSPRWWRMVQPWVSLLGRDVGTLLARSLQALTPPEGMDGVHWEETPGPTSQWIHRACCIPD", "length": 1923, "header": "tr|A0A8V0Z8U7-1|A0A8V0Z8U7_CHICK Isoform 1 of Retinoic acid induced 1 OS=Gallus gallus OX=9031 GN=RAI1 PE=4 SV=1 CANONICAL=A0A8V0Z8U7-1" }, "locus": { "chromosome": "14", "start_pos": 4911372, "end_pos": 4905604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042368.1", "url": "https://www.ensembl.org/id/ENSGALT00010042368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024858.1", "url": "https://www.ensembl.org/id/ENSGALP00010024858.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1145, "start_aa": "Thr", "end_pos": 1145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1145", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1911, "start_aa": "Thr", "end_pos": 1911, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1911", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8B9-1", "uniprot_ac": "A0A8V0Z8B9", "uniprot_id": "A0A8V0Z8B9_CHICK", "mass": { "chemical_mass": 66390.0, "monoisotopic_mass": 66390.0 }, "refseq": {}, "gene_names": [ { "name": "HHAT", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ] } ], "protein_names": [ { "name": "Hedgehog acyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HHAT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9", "locus": { "chromosome": "3", "start_pos": 22168549, "end_pos": 22352611, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018882", "url": "https://www.ensembl.org/id/ENSGALG00010018882" } ] } } ], "crossref": [ { "id": "A0A8V0Z8B9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8B9", "database": "AlphaFoldDB", "categories": [] }, { "id": "771269", "url": "https://www.ncbi.nlm.nih.gov/gene/771269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771269", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771269", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWAQTYT", "url": "https://omabrowser.org/oma/group/AWAQTYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1W4", "url": "https://www.orthodb.org/?gene=A0A8V0Z1W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1W9", "url": "https://www.orthodb.org/?gene=A0A8V0Z1W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9B4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13285:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13285:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5358346", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z1W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEGQIICENSSNCGTFIAELRLALNLDGQKLKSGYLSGVLLWEKIDCLFKSCSKELLKYLHYLDRKISSLLVLNIDRKVCLFHHLWVNVHHMVKKMACK", "length": 570, "header": "tr|A0A8V0Z8B9-1|A0A8V0Z8B9_CHICK Isoform 1 of Hedgehog acyltransferase OS=Gallus gallus OX=9031 GN=HHAT PE=3 SV=1 CANONICAL=A0A8V0Z8B9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9/entry#A0A8V0Z1W4-1", "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEEQTTSSEIPCIRSLFQASSLSAEVYV", "length": 499, "header": "tr|A0A8V0Z1W4-1|A0A8V0Z8B9_CHICK Computationally mapped isoform of Hedgehog acyltransferase OS=Gallus gallus OX=9031 GN=HHAT PE=3 SV=1 CANONICAL=A0A8V0Z8B9-1" }, "locus": { "chromosome": "3", "start_pos": 22351588, "end_pos": 22210946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045648.1", "url": "https://www.ensembl.org/id/ENSGALT00010045648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027218.1", "url": "https://www.ensembl.org/id/ENSGALP00010027218.1" } ] } }, { "isoform_ac": "A0A8V0Z1W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9/entry#A0A8V0Z1W9-1", "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEGNSLRKKRGRKSSLKYSLTQSLFSRNNNNPKEIAQYLH", "length": 511, "header": "tr|A0A8V0Z1W9-1|A0A8V0Z8B9_CHICK Computationally mapped isoform of Hedgehog acyltransferase OS=Gallus gallus OX=9031 GN=HHAT PE=3 SV=1 CANONICAL=A0A8V0Z8B9-1" }, "locus": { "chromosome": "3", "start_pos": 22351588, "end_pos": 22168569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045659.1", "url": "https://www.ensembl.org/id/ENSGALT00010045659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027223.1", "url": "https://www.ensembl.org/id/ENSGALP00010027223.1" } ] } }, { "isoform_ac": "A0A8V0Z8B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9/entry#A0A8V0Z8B9-1", "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEGQIICENSSNCGTFIAELRLALNLDGQKLKSGYLSGVLLWEKIDCLFKSCSKELLKYLHYLDRKISSLLVLNIDRKVCLFHHLWVNVHHMVKKMACK", "length": 570, "header": "tr|A0A8V0Z8B9-1|A0A8V0Z8B9_CHICK Isoform 1 of Hedgehog acyltransferase OS=Gallus gallus OX=9031 GN=HHAT PE=3 SV=1 CANONICAL=A0A8V0Z8B9-1" }, "locus": { "chromosome": "3", "start_pos": 22351588, "end_pos": 22250814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045643.1", "url": "https://www.ensembl.org/id/ENSGALT00010045643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027217.1", "url": "https://www.ensembl.org/id/ENSGALP00010027217.1" } ] } }, { "isoform_ac": "A0A8V0Z9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9/entry#A0A8V0Z9B4-1", "sequence": { "sequence": "MKNSRAAPRPVVLPAWEMCAYLFLTIGSHFYSFYEAYQVSQKYEDEIDRSFGLEQGTLFWGLKKDALDFEWSYWIEWGREYILWLLAGHLLVSQMCRLFMDKYKPWCLMVYGMAACWFLLGIKGFAVILVHTAISFAVAQFQIPLLTWLCSLILLSTLRIPAVEEAKREWYDTENEYYLLLFTVSVRCLFNTSFSLEYCWNGRAQKSSHSFLWMLAYVFYYPMFHNGPLMNFDEFSKQMRKQEAFSLKTNLVILIVGIIRIFFWWCLAELMIHFMYIHAICSTSSSLEAMSYWALGGVALAQVLFFYVKYLVLYGIAALLLRMDGLRPPALPRCVSLMHSFTKMWRSFDVGLHRFLVRYIYVPMGGSQSSLPGMLFSTALTFAFVSYWHGGQSYLWYWGVLNWLGVIVENGVKRILSVSPIQDLIERFFSPRVHRRLHAVLASVCTSMLILSNLIFLGGNHVGKVYWNRIFMEGWPWATLTVLGLLYCYAHVGIEWEHSYAVTPE", "length": 505, "header": "tr|A0A8V0Z9B4-1|A0A8V0Z9B4_CHICK Computationally mapped isoform of Hedgehog acyltransferase OS=Gallus gallus OX=9031 GN=HHAT PE=3 SV=1 CANONICAL=A0A8V0Z8B9-1" }, "locus": { "chromosome": "3", "start_pos": 22351588, "end_pos": 22206007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045653.1", "url": "https://www.ensembl.org/id/ENSGALT00010045653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027221.1", "url": "https://www.ensembl.org/id/ENSGALP00010027221.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771269", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771269", "resource": "KEGG Pathway" }, { "id": "R-GGA-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GIY5-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "Hhat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRAPANPLSRQPGATSQAKAFTPAASDRRSPQPSRVLPGPGLRAAGCRDAFFPAHSALHAAIQKLSTLHWEAESPAMLSRWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGGLKKDPTDFEWNFWLEWGKQRLVWLLLGHMAVSQLATLLTKKHRPWIIMIYGMWACWCVLGAPGVVMVLLHTTIAFCVAQFRSMLLSWLCSLLLLSTLRLQSVEEVKRRWYKTESEYYLLQFTLTVRCLYYTSFSLELCRQPPSAQRACFSFPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELSSLQHSLCILAKGLGRLLCWWWLAELMVHLMYMHALYSSIPLLESVSCWTLGGLALAQVLFFYVKYLVLFGAPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTAMTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLQTPCVRETLARHLSPQARRRLHALLASCSTSMLILFNLVFLEGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVGIAWAQTYTVL", "length": 570 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9T5F1-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "HHAT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPRWELSLYLLASIGFHFYSFYEVYKVSREHEEELDREFDLETGTLFRGLKKDPTDFEWSFWMEWGKERLVWLFLGHMSVSQVANLISRKHKPWILAVYGMWACRCVLGTQGTAMVLIHATISFCVAQFRSQFLSWLCSLSLLSTLRLQDVEEVKRGWYKTENEYYLLQFTLTVRCLYYTSFSLELCWQPPPAERPFYSLPWMLAYVFYYPVFHNGPVLSFPEFIAQMQQQEQSSPKTSLSILALGLGRLLFYWWLAELMVHLMYMHAIYSSASLLRAVSSWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLRPPPLPRCVSTMFSFTGMWRHFDVGLHDFLVRYVYIPAGGSQHGLLGALFSTAMTFAFVSFWHGGNDYLWCWATLNWLGVTVENGVQKLVQRPHVQHSLAQFLSPGARRRLHAALASCSTSMLILSNLVFLGGSQVGEIYWDRIFIQGWPWVTLSVLGFLYCYSHVGIAWAHTYSGH", "length": 493 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S2U1-1", "protein_name": "Hedgehog acyltransferase", "gene_name": "HHAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPRWELSFYLFASLGFHFYSFYEVFKVSREHEEELDQEFDLETDSLFGGLKKDPTDFEWSFWMEWGKQRLAWLLLGHVGVSQVANLLARKHRPWILAAYGMWACHCALGTRGTAMVLLHTTISFCVAQFRSLALSWLCSLFLLSTLRLQDVEEVKRGWYETENEYYLLQFTLTVRCLYYTSFSLELCWQQLPAERAFYSFPWMVAYVFYYPVFHNGPILSFPEFLTQMQPREQGSLKASFSILVRGLGRLLFYWWLVELMVHLMYMHAICSSAPLLSAVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLSPPPLPRCVSTMFSFTGMWRYFDVGLHDFLVRYVYIPVGGSQHGLLGTLFSTAVTFAFVSYWHGGNDYLWCWAALNWLGVTVESGVRRLVQKPSIQDSLAQVLSPQARRRFHAALASCSTSMLILSNLVFLGGNQVGKSTGIGSSFKAGHG", "length": 467 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F8W2J4-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT", "gene_name": "hhat", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTPKWELVSLPRWEMVAYWILSFSSHFYSFYQLHSFSKEHEVSLDKEVQLERGFLLWGFKKDPTDFEWSFWNEWAWRSLLWSLIGHAVVSRLAYYYLPQYRLAVFAMYGLISAGWILGVRGVIVLMLHLSISLVVAQLRSPVLSWFCSLLLLSTLNVSALQDLQRGWYTSEDQYYLLLFSTAVCSLHCISFCLEMCWHPLQAGRPKHCSSLQNCALKTLIYQFLKLTAFCFYHPLFYNGPIMTYKDFSEQIERPLCKVSALHVFSGILRLCVWWCLAEFMIHFMYMHAIQSNETYLEMLPPWAMGGLALALVQFFYVKYLVLFGAVSLLVRLDGLEPPTLPRCVSIMYSFTGMWRHFDVGLYKWLIRYIYVPLGGSRHGAFRKLLSTALAFGFVCFWHGCHDYLLYWALLNWVGVLVENAFALLFSSPPLRHAIVYCLTPRMQRRGLALISAFSTAFLILSNLFFLGGTHVGRIFWKKLFVQDWSSVAVPMVAFLYCFAQVGIEWDMR", "length": 508 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5VTY9-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT", "gene_name": "HHAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD", "length": 493 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMT9-1", "protein_name": "Protein-cysteine N-palmitoyltransferase HHAT", "gene_name": "Hhat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPGWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGGLKKDPTDFEWNFWMEWGKRRLVWLFIGHMAVSQLATLLTKKHRPWIVMVYGMWACWCVLGAPGVVMVLLHSTIAFCVAQFRSVLLSWLCSLLLLSTLRLQSVEEVKRRWYKTENEYYLLQFTLTVRCLYYTSFSLELCRQPPSAQPTPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELNSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVDIAWAQTYTVL", "length": 499 }, "evidence": [ { "id": "A0A8V0Z8B9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z912-1", "uniprot_ac": "A0A8V0Z912", "uniprot_id": "A0A8V0Z912_CHICK", "mass": { "chemical_mass": 36723.0, "monoisotopic_mass": 36723.0 }, "refseq": { "ac": "XP_003641841", "name": "protein FAM131A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641841" }, "gene_names": [ { "name": "FAM131A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912" } ] }, { "name": "FAM131A", "type": "synonym", "evidence": [ { "id": "XP_003641841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641841" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 131 member A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912/entry#names_and_taxonomy" } ] }, { "name": "protein FAM131A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641841" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641841.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641841" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z912", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM131A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912", "locus": { "chromosome": "9", "start_pos": 15618469, "end_pos": 15613716, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017554", "url": "https://www.ensembl.org/id/ENSGALG00010017554" } ] } } ], "crossref": [ { "id": "A0A8V0Z912", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z912", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858502", "url": "https://www.ncbi.nlm.nih.gov/gene/100858502", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858502", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858502", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACISQVV", "url": "https://omabrowser.org/oma/group/ACISQVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1Y7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z912", "url": "https://www.orthodb.org/?gene=A0A8V0Z912", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15736:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15736:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z912", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z912-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCIGSKTTIVAVDTTLCVEWKEVKALSPLRAARPAPLPRLLRQASFDSQDFLEVNVEDTVEMLPKSRRALTIQEIAALARSSLHGISQVVKEHVTKPTAMAQGRVAHLIEWKGWCKPVEPPTALESAFNSYCHLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSNDESYDEDFMPSSESSLPAEHHPGAALLRDLLRGHLCQLGARHGSCEPESDSSHTLSPKTLCSSLCSLEMVSPSELTAKLLGSLGGELPPPSSQSALRGLVWPRCQDSLSPMPYAEACLSPAEDEVVLSKDFALRRKISDVASSGVVSLEEEDEEEEEEEEEDEAEEP", "length": 338, "header": "tr|A0A8V0Z912-1|A0A8V0Z912_CHICK Isoform 1 of Family with sequence similarity 131 member A OS=Gallus gallus OX=9031 GN=FAM131A PE=3 SV=1 CANONICAL=A0A8V0Z912-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912/entry#A0A8V0Z1Y7-1", "sequence": { "sequence": "MRSGGNADGAEPAVVPAPGPPPGAWAASAPKPPSVNVEDTVEMLPKSRRALTIQEIAALARSSLHGISQVVKEHVTKPTAMAQGRVAHLIEWKGWCKPVEPPTALESAFNSYCHLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSNDESYDEDFMPSSESSLPAEHHPGAALLRDLLRGHLCQLGARHGSCEPESDSSHTLSPKTLCSSLCSLEMVSPSELTAKLLGSLGGELPPPSSQSALRGLVWPRCQDSLSPMPYAEACLSPAEDEVVLSKDFALRRKISDVASSGVVSLEEEDEEEEEEEEEDEAEEP", "length": 318, "header": "tr|A0A8V0Z1Y7-1|A0A8V0Z912_CHICK Computationally mapped isoform of Family with sequence similarity 131 member A OS=Gallus gallus OX=9031 GN=FAM131A PE=3 SV=1 CANONICAL=A0A8V0Z912-1" }, "locus": { "chromosome": "9", "start_pos": 15617465, "end_pos": 15613975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042432.1", "url": "https://www.ensembl.org/id/ENSGALT00010042432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024922.1", "url": "https://www.ensembl.org/id/ENSGALP00010024922.1" } ] } }, { "isoform_ac": "A0A8V0Z912-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z912/entry#A0A8V0Z912-1", "sequence": { "sequence": "MGCIGSKTTIVAVDTTLCVEWKEVKALSPLRAARPAPLPRLLRQASFDSQDFLEVNVEDTVEMLPKSRRALTIQEIAALARSSLHGISQVVKEHVTKPTAMAQGRVAHLIEWKGWCKPVEPPTALESAFNSYCHLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSNDESYDEDFMPSSESSLPAEHHPGAALLRDLLRGHLCQLGARHGSCEPESDSSHTLSPKTLCSSLCSLEMVSPSELTAKLLGSLGGELPPPSSQSALRGLVWPRCQDSLSPMPYAEACLSPAEDEVVLSKDFALRRKISDVASSGVVSLEEEDEEEEEEEEEDEAEEP", "length": 338, "header": "tr|A0A8V0Z912-1|A0A8V0Z912_CHICK Isoform 1 of Family with sequence similarity 131 member A OS=Gallus gallus OX=9031 GN=FAM131A PE=3 SV=1 CANONICAL=A0A8V0Z912-1" }, "locus": { "chromosome": "9", "start_pos": 15617465, "end_pos": 15614046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042429.1", "url": "https://www.ensembl.org/id/ENSGALT00010042429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024919.1", "url": "https://www.ensembl.org/id/ENSGALP00010024919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858502", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858502", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HRD2-1", "protein_name": "Protein FAM131A isoform X2", "gene_name": "Fam131a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGIDTDMAGPLGTHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPTEEEPDSCKDHPLLCPLPVGSWERQQQVSDVASSGVVSLDEDEVEPEDQ", "length": 364 }, "evidence": [ { "id": "A0A8V0Z912", "url": "https://omabrowser.org/oma/group/A0A8V0Z912/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1UIP4-1", "protein_name": "Family with sequence similarity 131 member A", "gene_name": "FAM131A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPTALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDESYDEDFVGGTDSDLAGQLPLGPHLQDLFTGHRFSRPMRQGSVEPESDCSQTVSPETLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPPAGSWERQRQASDVASSGVVSLDEDEVEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A8V0Z912", "url": "https://omabrowser.org/oma/group/A0A8V0Z912/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADK8-1", "protein_name": "Family with sequence similarity 131, member A", "gene_name": "Fam131a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGADTDMAGPLGSHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLSESCLSPAEEEPDSCKDCQLLCPLPTGSWERQQQVSEVASSGVASLDEDEVDQ", "length": 361 }, "evidence": [ { "id": "A0A8V0Z912", "url": "https://omabrowser.org/oma/group/A0A8V0Z912/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJN3-1", "protein_name": "Family with sequence similarity 131 member A", "gene_name": "FAM131A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTIAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDESYDEDFAGGTDSDLTGQMPLGPHLQDLFTGHRFSRPVRQGSVEPESDCSQTVSPETLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCLPPVSSWERQRQASDVASSGVVSLDEDEVEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A8V0Z912", "url": "https://omabrowser.org/oma/group/A0A8V0Z912/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UXB0-3", "protein_name": "Protein FAM131A", "gene_name": "FAM131A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVSSDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDDSYDEDFAGGMDTDMAGQLPLGPHLQDLFTGHRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPLTGSWERQRQASDLASSGVVSLDEDEAEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A8V0Z912", "url": "https://omabrowser.org/oma/group/A0A8V0Z912/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWU3-1", "protein_name": "Protein FAM131A", "gene_name": "Fam131a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"A0A8V0Z972", "url": "https://www.orthodb.org/?gene=A0A8V0Z972", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z975", "url": "https://www.orthodb.org/?gene=A0A8V0Z975", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z252", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z252", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z252-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z252-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z972", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z972-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z975", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z975", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z975-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z975-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPLPAPARPAPGPHKPTAHPSTSSRQPAPAPSRSGRTAASPGPSARAGDRAQEEEVVQPSPRPTQRRRCPAAASMGSLRERCARVFEACDEGNKGYLNREDFEVAVVMLFGYKLSEVEVDSIMSSVRPGNSGILFEKFLNLMSAKKSAQLHSDETREIFTAFDMQDRGFLTFEDFKKTINSVLPKLSERIIIEAFSFHTVCTAIGDSSCVITSVPAILLVNACKNLCYPFIHETAIL", "length": 238, "header": "tr|A0A8V0Z972-1|A0A8V0Z972_CHICK Isoform 1 of EF-hand calcium binding domain 11 OS=Gallus gallus OX=9031 GN=EFCAB11 PE=4 SV=1 CANONICAL=A0A8V0Z972-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z252-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972/entry#A0A8V0Z252-1", "sequence": { "sequence": "MVPLPAPARPAPGPHKPTAHPSTSSRQPAPAPSRSGRTAASPGPSARAGDRAQEEEVVQPSPRPTQRRRCPAAASMGSLRERCARVFEACDEGNKGYLNREDFEVAVVMLFGYKLSEVEVDSIMSSVRPGNSGILFEKFLNLMSAKKSAQLHSDETREIFTAFDMQDRGFLTFEDFKKTINSVLPKLSERIIIEAFSCGALQESHQQRLKHYEQEEPAG", "length": 219, "header": "tr|A0A8V0Z252-1|A0A8V0Z972_CHICK Computationally mapped isoform of EF-hand calcium binding domain 11 OS=Gallus gallus OX=9031 GN=EFCAB11 PE=4 SV=1 CANONICAL=A0A8V0Z972-1" }, "locus": { "chromosome": "5", "start_pos": 43197268, "end_pos": 43150193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042497.1", "url": "https://www.ensembl.org/id/ENSGALT00010042497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024987.1", "url": "https://www.ensembl.org/id/ENSGALP00010024987.1" } ] } }, { "isoform_ac": "A0A8V0Z972-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972/entry#A0A8V0Z972-1", "sequence": { "sequence": "MVPLPAPARPAPGPHKPTAHPSTSSRQPAPAPSRSGRTAASPGPSARAGDRAQEEEVVQPSPRPTQRRRCPAAASMGSLRERCARVFEACDEGNKGYLNREDFEVAVVMLFGYKLSEVEVDSIMSSVRPGNSGILFEKFLNLMSAKKSAQLHSDETREIFTAFDMQDRGFLTFEDFKKTINSVLPKLSERIIIEAFSFHTVCTAIGDSSCVITSVPAILLVNACKNLCYPFIHETAIL", "length": 238, "header": "tr|A0A8V0Z972-1|A0A8V0Z972_CHICK Isoform 1 of EF-hand calcium binding domain 11 OS=Gallus gallus OX=9031 GN=EFCAB11 PE=4 SV=1 CANONICAL=A0A8V0Z972-1" }, "locus": { "chromosome": "5", "start_pos": 43197268, "end_pos": 43171426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042494.1", "url": "https://www.ensembl.org/id/ENSGALT00010042494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024984.1", "url": "https://www.ensembl.org/id/ENSGALP00010024984.1" } ] } }, { "isoform_ac": "A0A8V0Z975-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972/entry#A0A8V0Z975-1", "sequence": { "sequence": "MVPLPAPARPAPGPHKPTAHPSTSSRQPAPAPSRSGRTAASPGPSARAGDRAQEEEVVQPSPRPTQRRRCPAAASMGSLRERCARVFEACDEGNKGYLNREDFEVAVVMLFGYKLSEVEVDSIMSSVRPGNSGILFEKFLNLMSAKKSAQLHSDETREIFTAFDMQDRGFLTFEDFKKTINSVLPKLSERIIIEAFRNWMLELQIERG", "length": 208, "header": "tr|A0A8V0Z975-1|A0A8V0Z975_CHICK Computationally mapped isoform of EF-hand calcium binding domain 11 OS=Gallus gallus OX=9031 GN=EFCAB11 PE=4 SV=1 CANONICAL=A0A8V0Z972-1" }, "locus": { "chromosome": "5", "start_pos": 43197268, "end_pos": 43142506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042499.1", "url": "https://www.ensembl.org/id/ENSGALT00010042499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024989.1", "url": "https://www.ensembl.org/id/ENSGALP00010024989.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z972", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z972" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 113, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8K9-1", "uniprot_ac": "A0A8V0Z8K9", "uniprot_id": "A0A8V0Z8K9_CHICK", "mass": { "chemical_mass": 42338.0, "monoisotopic_mass": 42338.0 }, "refseq": {}, "gene_names": [ { "name": "PHF13", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ] } ], "protein_names": [ { "name": "PHD finger protein 13", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Modulates chromatin structure and DNA damage response by regulating key determinants of chromatin compaction and DNA damage response. Binds H3K4me3-containing chromatin and promotes DNA condensation by recruiting corepressors such as TRIM28 and H3K9 methyltransferase SETDB1. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. Increases both chromatin-associated levels and activity of H3K9 methyltransferases, such as SETDB1, thus enhancing H3K9 trimethylation. Essential for testicular stem-cell differentiation and sustained spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z262", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z262#function" }, { "database": "UniProtKB", "id": "ARBA00055120", "url": "https://www.uniprot.org/uniprotkb/ARBA00055120#function" }, { "database": "UniProtKB", "id": "A0A8V0Z815", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z815#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHF13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9", "locus": { "chromosome": "21", "start_pos": 546349, "end_pos": 550936, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018933", "url": "https://www.ensembl.org/id/ENSGALG00010018933" } ] } } ], "crossref": [ { "id": "A0A8V0Z8K9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8K9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15632", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15632", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101750144", "url": "https://www.ncbi.nlm.nih.gov/gene/101750144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750144", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPLHPQC", "url": "https://omabrowser.org/oma/group/IPLHPQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z262", "url": "https://www.orthodb.org/?gene=A0A8V0Z262", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z815", "url": "https://www.orthodb.org/?gene=A0A8V0Z815", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8K9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14571:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14571:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z262", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z262", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z262-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z262-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z815", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z815", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z815-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z815-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SGCGTWAGVAGGGGAVRRCAVPPRAVGVGLRVGSGGGGRGSGRERLRQPRRGDGGRGGGVWGGFGTGRKRGAGGGAAPGSARSAGSGERLRGEADFSPTSRRHRTVEDFNKFCTFVLAYAGYIPYPQEETPLRNSPSPPNSTGGTIDSDSWDPRFNDIPSSVSLPAKNRKNFSQLKRAKPYSSLFQRAKPGNFLPERKQIDKIRKKKKLKRRETEVSAEEDYEEKLLELEAEDSYTETPMSPSSEGDPQSVAEHCSVWDSDTASSVAYPPGTGEQAVEIQSVGKRTVIRQGKQVVFRDEDGTGDDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCRDSKFDIRRSNRSRTGSRRRFLD", "length": 387, "header": "tr|A0A8V0Z8K9-1|A0A8V0Z8K9_CHICK Isoform 1 of PHD finger protein 13 OS=Gallus gallus OX=9031 GN=PHF13 PE=4 SV=1 CANONICAL=A0A8V0Z8K9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z262-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9/entry#A0A8V0Z262-1", "sequence": { "sequence": "MDSDSCASPFAPEDFSPTSRRHRTVEDFNKFCTFVLAYAGYIPYPQEETPLRNSPSPPNSTGGTIDSDSWDPRFNDIPSSVSLPAKNRKNFSQLKRAKPYSSLFQRAKPGNFLPERKQIDKIRKKKKLKRRETEVSAEEDYEEKLLELEAEDSYTETPMSPSSEGDPQSVAEHCSVWDSDTASSVAYPPGTGEQAVEIQSVGKRTVIRQGKQVVFRDEDGTGDDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCRDSKFDIRRSNRSRTGSRRRFLD", "length": 306, "header": "tr|A0A8V0Z262-1|A0A8V0Z8K9_CHICK Computationally mapped isoform of PHD finger protein 13 OS=Gallus gallus OX=9031 GN=PHF13 PE=4 SV=1 CANONICAL=A0A8V0Z8K9-1" }, "locus": { "chromosome": "21", "start_pos": 550854, "end_pos": 548554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045821.1", "url": "https://www.ensembl.org/id/ENSGALT00010045821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027310.1", "url": "https://www.ensembl.org/id/ENSGALP00010027310.1" } ] } }, { "isoform_ac": "A0A8V0Z815-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9/entry#A0A8V0Z815-1", "sequence": { "sequence": "GGGCGAASDFSPTSRRHRTVEDFNKFCTFVLAYAGYIPYPQEETPLRNSPSPPNSTGGTIDSDSWDPRFNDIPSSVSLPAKNRKNFSQLKRAKPYSSLFQRAKPGNFLPERKQIDKIRKKKKLKRRETEVSAEEDYEEKLLELEAEDSYTETPMSPSSEGDPQSVAEHCSVWDSDTASSVAYPPGTGEQAVEIQSVGKRTVIRQGKQVVFRDEDGTGDDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCRDSKFDIRRSNRSRTGSRRRFLD", "length": 301, "header": "tr|A0A8V0Z815-1|A0A8V0Z815_CHICK Computationally mapped isoform of PHD finger protein 13 OS=Gallus gallus OX=9031 GN=PHF13 PE=4 SV=1 CANONICAL=A0A8V0Z8K9-1" }, "locus": { "chromosome": "21", "start_pos": 550405, "end_pos": 548554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045811.1", "url": "https://www.ensembl.org/id/ENSGALT00010045811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027302.1", "url": "https://www.ensembl.org/id/ENSGALP00010027302.1" } ] } }, { "isoform_ac": "A0A8V0Z8K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9/entry#A0A8V0Z8K9-1", "sequence": { "sequence": "SGCGTWAGVAGGGGAVRRCAVPPRAVGVGLRVGSGGGGRGSGRERLRQPRRGDGGRGGGVWGGFGTGRKRGAGGGAAPGSARSAGSGERLRGEADFSPTSRRHRTVEDFNKFCTFVLAYAGYIPYPQEETPLRNSPSPPNSTGGTIDSDSWDPRFNDIPSSVSLPAKNRKNFSQLKRAKPYSSLFQRAKPGNFLPERKQIDKIRKKKKLKRRETEVSAEEDYEEKLLELEAEDSYTETPMSPSSEGDPQSVAEHCSVWDSDTASSVAYPPGTGEQAVEIQSVGKRTVIRQGKQVVFRDEDGTGDDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCRDSKFDIRRSNRSRTGSRRRFLD", "length": 387, "header": "tr|A0A8V0Z8K9-1|A0A8V0Z8K9_CHICK Isoform 1 of PHD finger protein 13 OS=Gallus gallus OX=9031 GN=PHF13 PE=4 SV=1 CANONICAL=A0A8V0Z8K9-1" }, "locus": { "chromosome": "21", "start_pos": 550574, "end_pos": 548554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045814.1", "url": "https://www.ensembl.org/id/ENSGALT00010045814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027304.1", "url": "https://www.ensembl.org/id/ENSGALP00010027304.1" } ] } }, { "isoform_ac": "A0A8V0ZFF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9/entry#A0A8V0ZFF6-1", "sequence": { "sequence": "EPRSRGGRLPPPVPAGARFPPPGRGHLVPLERGASLGPGAERGGGAVGREWRRRWRPAVVPPPLPSASRREGGCGAGSGGQDDFSPTSRRHRTVEDFNKFCTFVLAYAGYIPYPQEETPLRNSPSPPNSTGGTIDSDSWDPRFNDIPSSVSLPAKNRKNFSQLKRAKPYSSLFQRAKPGNFLPERKQIDKIRKKKKLKRRETEVSAEEDYEEKLLELEAEDSYTETPMSPSSEGDPQSVAEHCSVWDSDTASSVAYPPGTGEQAVEIQSVGKRTVIRQGKQVVFRDEDGTGDDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCRDSKFDIRRSNRSRTGSRRRFLD", "length": 375, "header": "tr|A0A8V0ZFF6-1|A0A8V0ZFF6_CHICK Computationally mapped isoform of PHD finger protein 13 OS=Gallus gallus OX=9031 GN=PHF13 PE=4 SV=1 CANONICAL=A0A8V0Z8K9-1" }, "locus": { "chromosome": "21", "start_pos": 550813, "end_pos": 548554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045816.1", "url": "https://www.ensembl.org/id/ENSGALT00010045816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027306.1", "url": "https://www.ensembl.org/id/ENSGALP00010027306.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101750144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750144", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2L648-1", "protein_name": "PHD finger protein 13", "gene_name": "phf13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVDGSTTCPFDKQGYSSTFKRKRTVEDFNKFCTFVLAYAGYIPYPQEEAHLRNSSSPPNSTGSTADSDGWDNQQLSCSLSSPDEPPPKNRKSFAGFKRPTSEDSEPQKRPKSAGLLLEGRKKADKVKKKKKLRKCKDEDFRNFAPFTPPRVEGEFSSLGRSIKEEPEDYISIPVPSTGFDHPAHTCSKPVSSSQSSAVCKEEPDIEHSCWGGSKSSDQEFEDVKKPSKLEREAMVLKEESFSAKRTVVRQGKQVVFRDEDGSADDEDIMVDSDDDSWDLVTCFCMKPFAGRAMIECNQCNTWIHLSCAKIRKSNVPETYICQRCKDSKFDIRRSNRSRVGSRKHLLD", "length": 348 }, "evidence": [ { "id": "A0A8V0Z8K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I5ZN36-1", "protein_name": "PHD finger protein 13", "gene_name": "Phf13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "CGPAPSERLRARCCRPLHRPGRAPPPRRPRPGGPYSGAGLPRPPLPLLPGSGPRAAPPGRGRGAGCAAGAGRSPRGPPCLSCGREAPGPAWPRDTPPPRSHRRPAPHGWAPHLPGPARAGRRRAPSAPGGRVGPWPPLRRRPALLSEALIPFPPAIFPGAKLKFFPSWSPVGSPCGLPSAGSARPTLLPVACGAGRGAGASGLLEQEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITSSVPDRCFSHLQPSLLQRAKPSDFLLDRKKTDKLKKKRRRKRRDSDVPGKEEYRGSLLKLEAADPYVEAPSSPTMQDIPQASADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "length": 489 }, "evidence": [ { "id": "A0A8V0Z8K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TN05-1", "protein_name": "PHD finger protein 13", "gene_name": "PHF13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSDSCAAAFHPEEYSPSYKRRRTVEDFNKFCTFVLAYAGYIPYPKEEVPLRSSPSPANSTAGTIDSDGWDASFADISSTVPLPVSDRCFGHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSDVPGKEGYVGGLLQLEAADPYAETPTSPTLQDIPQAAGDPCSGWDSDTPSSGSCTTVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "length": 300 }, "evidence": [ { "id": "A0A8V0Z8K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86YI8-1", "protein_name": "PHD finger protein 13", "gene_name": "PHF13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD", "length": 300 }, "evidence": [ { "id": "A0A8V0Z8K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2W6-1", "protein_name": "PHD finger protein 13", "gene_name": "Phf13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSDSCAAAFHPEEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTGFSDITPSVPDRCFSHLQPSLLQRAKPSNYLLDRKTTDKLKKKKRRKRRDSDIPVKEGFRESLLKLEAADPYVETPSSPTMQDIPQASADPCSGWDSDTPSSGSCATVSPDQVTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "length": 296 }, "evidence": [ { "id": "A0A8V0Z8K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" }, { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K9" }, { "id": "SM00249", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Zinc finger PHD-type", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 365, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 375, "end_pos": 377 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z826-1", "uniprot_ac": "A0A8V0Z826", "uniprot_id": "A0A8V0Z826_CHICK", "mass": { "chemical_mass": 90433.0, "monoisotopic_mass": 90433.0 }, "refseq": {}, "gene_names": [ { "name": "SYT14", "type": "recommended", "evidence": [ { "id": "A0A8V0Z826", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826" } ] } ], "protein_names": [ { "name": "Synaptotagmin 14", "type": "synonym", "evidence": [ { "id": "A0A8V0Z826", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q027", "url": "https://www.uniprot.org/uniprotkb/A0A1D5Q027#function" }, { "database": "UniProtKB", "id": "ARBA00056709", "url": "https://www.uniprot.org/uniprotkb/ARBA00056709#function" }, { "database": "UniProtKB", "id": "A0A8V0Z267", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z267#function" }, { "database": "UniProtKB", "id": "A0A8V0Z820", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z820#function" }, { "database": "UniProtKB", "id": "A0A8V0Z826", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826#function" }, { "database": "UniProtKB", "id": "A0A8V0Z830", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z830#function" }, { "database": "UniProtKB", "id": "E1C1Z1", "url": "https://www.uniprot.org/uniprotkb/E1C1Z1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z826", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826", "locus": { "chromosome": "3", "start_pos": 22416538, "end_pos": 22499529, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018936", "url": "https://www.ensembl.org/id/ENSGALG00010018936" } ] } } ], "crossref": [ { "id": "A0A8V0Z826", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z826", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009884", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009884", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428566", "url": "https://www.ncbi.nlm.nih.gov/gene/428566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MTFLFWY", "url": "https://omabrowser.org/oma/group/MTFLFWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5Q027", "url": "https://www.orthodb.org/?gene=A0A1D5Q027", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z267", "url": "https://www.orthodb.org/?gene=A0A8V0Z267", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z820", "url": "https://www.orthodb.org/?gene=A0A8V0Z820", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z826", "url": "https://www.orthodb.org/?gene=A0A8V0Z826", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z830", "url": "https://www.orthodb.org/?gene=A0A8V0Z830", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1Z1", "url": "https://www.orthodb.org/?gene=E1C1Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5Q027", "url": "https://www.uniprot.org/uniprotkb/A0A1D5Q027", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5Q027-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5Q027-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z267", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z267-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z267-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z820", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z820", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z820-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z820-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z826", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z826-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z830", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z830", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z830-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1Z1", "url": "https://www.uniprot.org/uniprotkb/E1C1Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1Z1-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFFRNLHQNLSLPSVSSLVDTLSSAVDDLTSVVGEVGYSVADSVTEQVTNMINGLRAEDESSKMQNDKTAQDRDENAPWLTEPKEINMKAKRDIAEQKEVQYSGSLEDTNQDGVSNHVVDENQYQLKGKDSNDCLEDTEVPWDFKNVGRPLKREAVGENDCFGNKLLKDTNLKSNKFTMQESIEKQDSCLHTIPDNSKNHLHKKIKPRSPGIDCNDSEEVRGMNISRDLETKFVKVQKQKLSDSSLKMHSNHPSCINEIKEKSEASFDRKEKSEGDASPTVAKVGNKKNSKKSEKKSRGLCNKKTAGKDNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 808, "header": "tr|A0A8V0Z826-1|A0A8V0Z826_CHICK Isoform 1 of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=1 CANONICAL=A0A8V0Z826-1" }, "isoforms": [ { "isoform_ac": "A0A1D5Q027-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#A0A1D5Q027-1", "sequence": { "sequence": "MLLLFLYINKKMCFENVGGFPDLDSGYPTRKNSQDKLYNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 517, "header": "tr|A0A1D5Q027-1|A0A8V0Z826_CHICK Computationally mapped isoform of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=2 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22473865, "end_pos": 22422705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045820.1", "url": "https://www.ensembl.org/id/ENSGALT00010045820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027309.1", "url": "https://www.ensembl.org/id/ENSGALP00010027309.1" } ] } }, { "isoform_ac": "A0A8V0Z267-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#A0A8V0Z267-1", "sequence": { "sequence": "MKVGSSNEGDEGPEAGGERTCGVHELICIRKVSPEAIGFLSAVGVFIVLMLLLFLYINKKMCFENVGGFPDLDSGYPTRKNSQDKLYNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 585, "header": "tr|A0A8V0Z267-1|A0A8V0Z826_CHICK Computationally mapped isoform of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=1 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22499495, "end_pos": 22422705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045826.1", "url": "https://www.ensembl.org/id/ENSGALT00010045826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027315.1", "url": "https://www.ensembl.org/id/ENSGALP00010027315.1" } ] } }, { "isoform_ac": "A0A8V0Z820-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#A0A8V0Z820-1", "sequence": { "sequence": "MAFFRNLHQNLSLPSVSSLVDTLSSAVDDLTSVVGEVGYSVADSVTEQVTNMINGLRAEDESSKMQNDKTAQDRDENAPWLTEPKEINMKAKRDIAEQKEVQYSGSLEDTNQDGVSNHVVDENQYQLKGKDSNDCLEDTEVPWDFKNVGRPLKREAVGENDCFGNKLLKDTNLKSNKFTMQESIEKQDSCLHTIPDNSKNHLHKKIKPRSPGIDCNDSEEVRGMNISRDLETKFVKVQKQKLSDSSLKMHSNHPSCINEIKEKSEASFDRKEKSEGDASPTVAKVGNKKNSKKSEKKSRGLCNKKTAGKANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 735, "header": "tr|A0A8V0Z820-1|A0A8V0Z820_CHICK Computationally mapped isoform of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=1 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22472463, "end_pos": 22422705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045818.1", "url": "https://www.ensembl.org/id/ENSGALT00010045818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027307.1", "url": "https://www.ensembl.org/id/ENSGALP00010027307.1" } ] } }, { "isoform_ac": "A0A8V0Z826-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#A0A8V0Z826-1", "sequence": { "sequence": "MAFFRNLHQNLSLPSVSSLVDTLSSAVDDLTSVVGEVGYSVADSVTEQVTNMINGLRAEDESSKMQNDKTAQDRDENAPWLTEPKEINMKAKRDIAEQKEVQYSGSLEDTNQDGVSNHVVDENQYQLKGKDSNDCLEDTEVPWDFKNVGRPLKREAVGENDCFGNKLLKDTNLKSNKFTMQESIEKQDSCLHTIPDNSKNHLHKKIKPRSPGIDCNDSEEVRGMNISRDLETKFVKVQKQKLSDSSLKMHSNHPSCINEIKEKSEASFDRKEKSEGDASPTVAKVGNKKNSKKSEKKSRGLCNKKTAGKDNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 808, "header": "tr|A0A8V0Z826-1|A0A8V0Z826_CHICK Isoform 1 of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=1 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22472463, "end_pos": 22422705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045823.1", "url": "https://www.ensembl.org/id/ENSGALT00010045823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027312.1", "url": "https://www.ensembl.org/id/ENSGALP00010027312.1" } ] } }, { "isoform_ac": "A0A8V0Z830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#A0A8V0Z830-1", "sequence": { "sequence": "MAFFRNLHQNLSLPSVSSLVDTLSSAVDDLTSVVGEVGYSVADSVTEQVTNMINGLRAEDESSKMQNDKTAQDRDENAPWLTEPKEINMKAKRDIAEQKEVQYSGSLEDTNQDGVSNHVVDENQYQLKGKDSNDCLEDTEVPWDFKNVGRPLKREAVGENDCFGNKLLKDTNLKSNKFTMQESIEKQDSCLHTIPDNSKNHLHKKIKPRSPGIDCNDSEEVRGMNISRDLETKFVKVQKQKLSDSSLKMHSNHPSCINEIKEKSEASFDRKEKSEGDASPTVAKVGNKKNSKKSEKKSRGLCNKKTAGKDNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQMCMHTCH", "length": 786, "header": "tr|A0A8V0Z830-1|A0A8V0Z830_CHICK Computationally mapped isoform of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=1 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22472463, "end_pos": 22418127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045832.1", "url": "https://www.ensembl.org/id/ENSGALT00010045832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027317.1", "url": "https://www.ensembl.org/id/ENSGALP00010027317.1" } ] } }, { "isoform_ac": "E1C1Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826/entry#E1C1Z1-1", "sequence": { "sequence": "MAIDGGERTCGVHELICIRKVSPEAIGFLSAVGVFIVLMLLLFLYINKKMCFENVGGFPDLDSGYPTRKNSQDKLYNSYMSKDQHGSSSESEDEALGKYHEALSRTQSSRLPVVDGRQQKNYVWETRQKYSPLSAEYDGYSSEASIDEANCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEVGDSKCEFSQCSNSPRCSYKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKPFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYSRTGGSSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYSVRRMKKERIVGEKIFHLTKLNLQGKMSVPVILEPSYSLSGCDSQMSMSEVSCSESTSSCQSLVHGSAPEILVGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEDELNHWTEMKESKGQQVCRWHTLLES", "length": 574, "header": "tr|E1C1Z1-1|A0A8V0Z826_CHICK Computationally mapped isoform of Synaptotagmin 14 OS=Gallus gallus OX=9031 GN=SYT14 PE=3 SV=2 CANONICAL=A0A8V0Z826-1" }, "locus": { "chromosome": "3", "start_pos": 22498317, "end_pos": 22422705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045824.1", "url": "https://www.ensembl.org/id/ENSGALT00010045824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027313.1", "url": "https://www.ensembl.org/id/ENSGALP00010027313.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AMJ4-1", "protein_name": "Synaptotagmin 14", "gene_name": "Syt14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFFKSFQQNLPSVSSLVDTISSAVEDLSTAVGEVSYAITDSVAGQVANMMHGFCPEEGSCTAEEATGSSKAQSTALQDTSTSKNTAHQKAQSDLDQKAKQTTGCNTSTPQRQEQEIYKQGLHIHEGQWATSEYQETGEAGGAAVKGLMSDGISAVKQKMRPAPTCHELEQTDKCEVSGVGNSGSDTNGLNKVSYQDVKGSLSSSGQNFLSVQKCMVTDSSKARLQHVPVGREQEKSGTVTKSKRLSDLEHSEHLEKAKSRNKHNGFKGNERSGNDHSPDDSTRNSRYRAQRSNAKEDTHSAPSTHCKNVFPRRIKEKTNPTKCDKVKGDMKAKKNEASSAKRGTAKSKVGKYSKILPEKDNSYMDRDEPGSSSESEDEALGKYHEALSRTHNSRWPLVDSRQKSYTWETRQKYSPLSAEYDGYSTEASIEDGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSASQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNPSGCDSQVSLSEVSCGDSTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELRHWSAMKESKGQQVCRWHALLES", "length": 859 }, "evidence": [ { "id": "A0A8V0Z826", "url": "https://omabrowser.org/oma/group/A0A8V0Z826/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NB59-1", "protein_name": "Synaptotagmin-14", "gene_name": "SYT14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES", "length": 555 }, "evidence": [ { "id": "A0A8V0Z826", "url": "https://omabrowser.org/oma/group/A0A8V0Z826/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z826", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z826", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z826", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z826" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 494, "end_pos": 613, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 660, "end_pos": 662 }, { "start_pos": 778, "end_pos": 780 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9L9-1", "uniprot_ac": "A0A8V0Z9L9", "uniprot_id": "A0A8V0Z9L9_CHICK", "mass": { "chemical_mass": 81507.0, "monoisotopic_mass": 81507.0 }, "refseq": {}, "gene_names": [ { "name": "POLR3E", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ] } ], "protein_names": [ { "name": "RNA polymerase III subunit E", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLR3E", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9", "locus": { "chromosome": "14", "start_pos": 8710447, "end_pos": 8684182, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018948", "url": "https://www.ensembl.org/id/ENSGALG00010018948" } ] } } ], "crossref": [ { "id": "A0A8V0Z9L9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9L9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416620", "url": "https://www.ncbi.nlm.nih.gov/gene/416620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416620", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416620", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSTCSPH", "url": "https://omabrowser.org/oma/group/KSTCSPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z282", "url": "https://www.orthodb.org/?gene=A0A8V0Z282", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8P5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9L9", "url": "https://www.orthodb.org/?gene=A0A8V0Z9L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12069:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12069:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z282", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z282-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z282-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIVPRNKPRKSFLYPSMANEEDDPIIQEIDVFLARSLLEKLYLFQYPIRPASMTYDDVTHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGTCTDETSTYSSKLMDKQTFCSSQAASNVSRYAAAVYRKGELHLTPLHGILQLRPSFTYLDKADAKHREREAANEGGDSSQDEAEDDVKQITVRFSRPETEQARQRRVQSYEFLQKRQAEEHWVHLHYYGLKDSRSEHERQYLFSQGHGLAENTELIKSPSEYLMMLMPPSVEEENNKPMAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGSGTDSTAVLRCIQQVAMLVQGNWVVKSDVLYPKDTSSPHSGVPAEVLCRGRDFVMWKFTQDRWVVRKEVAAVTKLCPEDVKDFLEHMSVARINKGWEFMLPYDEDFVKKHPDIVQRQRMLWMGIQAKLEKVYNLVKEHLTPKKQETQSGHPLLVSGEQRVNMAKAKVKQSYGQLEKEFQKQKAELKSNDTSSKIDVSNIRIKEEPVSDEEPMDTSVYEGLNNGIANGLHAEEDSMDSLNGHLPGSCSDRVAQELKAFVSSTFKKQFVLTLSELKRLFNLHLASLPPGHILFSGISDKMLQDMVLDIGCKQILVPFPPQTAASPDELKVYALWEAGDIYDQHRQVLLEIFSKNYRVRRNVIQNQLSQDLNKQEVDRVLKDCCVSYGGMWYLKGTVQS", "length": 714, "header": "tr|A0A8V0Z9L9-1|A0A8V0Z9L9_CHICK Isoform 1 of RNA polymerase III subunit E OS=Gallus gallus OX=9031 GN=POLR3E PE=4 SV=1 CANONICAL=A0A8V0Z9L9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z282-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9/entry#A0A8V0Z282-1", "sequence": { "sequence": "MANEEDDPIIQEIDVFLARSLLEKLYLFQYPIRPASMTYDDVTHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGTCTDETSTYSSKLMDKQTFCSSQAASNVSRYAAAVYRKGELHLTPLHGILQLRPSFTYLDKADAKHREREAANEGGDSSQDEAEDDVKQITVRFSRPETEQARQRRVQSYEFLQKRQAEEHWVHLHYYGLKDSRSEHERQYLFSQGHGLAENTELIKSPSEYLMMLMPPSVEEENNKPMAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGSGTDSTAVLRCIQQVAMLVQGNWVVKSDVLYPKDTSSPHSGVPAEVLCRGRDFVMWKFTQDRWVVRKEVAAVTKLCPEDVKDFLEHMSVARINKGWEFMLPYDEDFVKKHPDIVQRQRMLWMGIQAKLEKVYNLVKEHLTPKKQETQSGHPLLVSGEQRVNMAKAKVKQSYGQLEKEFQKQKAELKSNDTSSKIDVSNIRIKEEPVSDEEPMDTSVYEGLNNGIANGLHAEEDSMDSLNGHLPGSCSDRVAQELKAFVSSTFKKQFVLTLSELKRLFNLHLASLPPGHILFSGISDKMLQDMVLDIGCKQILVPVSIFFLLAHCGGEVGEQLNIGAVKCLHLGLD", "length": 647, "header": "tr|A0A8V0Z282-1|A0A8V0Z9L9_CHICK Computationally mapped isoform of RNA polymerase III subunit E OS=Gallus gallus OX=9031 GN=POLR3E PE=4 SV=1 CANONICAL=A0A8V0Z9L9-1" }, "locus": { "chromosome": "14", "start_pos": 8703154, "end_pos": 8687185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045855.1", "url": "https://www.ensembl.org/id/ENSGALT00010045855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027330.1", "url": "https://www.ensembl.org/id/ENSGALP00010027330.1" } ] } }, { "isoform_ac": "A0A8V0Z8P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9/entry#A0A8V0Z8P5-1", "sequence": { "sequence": "MANEEDDPIIQEIDVFLARSLLEKLYLFQYPIRPASMTYDDVTHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGTCTDETSTYSSKLMDKQTFCSSQAASNVSRYAAAVYRKGELHLTPLHGILQLRPSFTYLDKADAKHREREAANEGGDSSQDEAEDDVKQITVRFSRPETEQARQRRVQSYEFLQKRQAEEHWVHLHYYGLKDSRSEHERQYLFSQGHGLAENTELIKSPSEYLMMLMPPSVEEENNKPMAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGSGTDSTAVLRCIQQVAMLVQGNWVVKSDVLYPKDTSSPHSGVPAEVLCRGRDFVMWKFTQDRWVVRKEVAAVTKLCPEDVKDFLEHMSVARINKGWEFMLPYDEDFVKKHPDIVQRQRMLWMGIQAKLEKVYNLVKEHLTPKKQETQSGHPLLVSGEQRVNMAKAKVKQSYGQLEKEFQKQKAELKSNDTSSKIDVSNIRIKEEPVSDEEPMDTSVYEGLNNGIANGLHAEEDSMDSLNGHLPGSCSDRVAQELKAFVSSTFKKQFVLTLSELKRLFNLHLASLPPGHILFSGISDKMLQDMVLDIGCKQILVPFPPQTAASPDELKVYALWEAGDIYDQHRQVLLEIFSKNYRVRRNVIQNQLSQDLNKQEVDRVLKDCCVSYGGMWYLKGTVQS", "length": 698, "header": "tr|A0A8V0Z8P5-1|A0A8V0Z8P5_CHICK Computationally mapped isoform of RNA polymerase III subunit E OS=Gallus gallus OX=9031 GN=POLR3E PE=4 SV=1 CANONICAL=A0A8V0Z9L9-1" }, "locus": { "chromosome": "14", "start_pos": 8709651, "end_pos": 8687185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045869.1", "url": "https://www.ensembl.org/id/ENSGALT00010045869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027339.1", "url": "https://www.ensembl.org/id/ENSGALP00010027339.1" } ] } }, { "isoform_ac": "A0A8V0Z9L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9/entry#A0A8V0Z9L9-1", "sequence": { "sequence": "MIVPRNKPRKSFLYPSMANEEDDPIIQEIDVFLARSLLEKLYLFQYPIRPASMTYDDVTHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGTCTDETSTYSSKLMDKQTFCSSQAASNVSRYAAAVYRKGELHLTPLHGILQLRPSFTYLDKADAKHREREAANEGGDSSQDEAEDDVKQITVRFSRPETEQARQRRVQSYEFLQKRQAEEHWVHLHYYGLKDSRSEHERQYLFSQGHGLAENTELIKSPSEYLMMLMPPSVEEENNKPMAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGSGTDSTAVLRCIQQVAMLVQGNWVVKSDVLYPKDTSSPHSGVPAEVLCRGRDFVMWKFTQDRWVVRKEVAAVTKLCPEDVKDFLEHMSVARINKGWEFMLPYDEDFVKKHPDIVQRQRMLWMGIQAKLEKVYNLVKEHLTPKKQETQSGHPLLVSGEQRVNMAKAKVKQSYGQLEKEFQKQKAELKSNDTSSKIDVSNIRIKEEPVSDEEPMDTSVYEGLNNGIANGLHAEEDSMDSLNGHLPGSCSDRVAQELKAFVSSTFKKQFVLTLSELKRLFNLHLASLPPGHILFSGISDKMLQDMVLDIGCKQILVPFPPQTAASPDELKVYALWEAGDIYDQHRQVLLEIFSKNYRVRRNVIQNQLSQDLNKQEVDRVLKDCCVSYGGMWYLKGTVQS", "length": 714, "header": "tr|A0A8V0Z9L9-1|A0A8V0Z9L9_CHICK Isoform 1 of RNA polymerase III subunit E OS=Gallus gallus OX=9031 GN=POLR3E PE=4 SV=1 CANONICAL=A0A8V0Z9L9-1" }, "locus": { "chromosome": "14", "start_pos": 8709651, "end_pos": 8686973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045860.1", "url": "https://www.ensembl.org/id/ENSGALT00010045860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027333.1", "url": "https://www.ensembl.org/id/ENSGALP00010027333.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416620", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416620", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LEK3-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5 isoform X1", "gene_name": "Polr3e", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTVNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 710 }, "evidence": [ { "id": "A0A8V0Z9L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZP45-1", "protein_name": "RNA polymerase III subunit E", "gene_name": "Polr3e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACTDETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEACFTAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINRGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGPSAPVVSGEQRVQTAKTKAQQNHAFLERELQRRKEQIRGTTVLPSVQIKEEPLSEEEADGDELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVARELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "length": 712 }, "evidence": [ { "id": "A0A8V0Z9L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R866-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5 isoform X1", "gene_name": "polr3e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASGDDDDPIIQEIDVYLARSLVEKLYLFQYPVRPGSMSYNNVTHLGAKIKPKQQKVELEVAMDTMSPNYSRSKGEQIALNVDGMSSEDSNVYTTKMMDKQTFSSIQATTNTSRYAAAVFHKGELHLTPLQGILQMRPSFTYLDKADTKHREREAANEAGDSSQDEAEDDVKQITVRFSRPESEQARQRRIQSYEFLQKKQAEEPWVHLHYHAIKDSRSEHERQYLYCQAMDTTENTELVKTPREYLSMLMPPLAEEKVVKPVGPSNVLSMAQLRTLPLGDQVKTLMKNVKVMPFANLMGLLASGTDSTAVLRCIQQVALLVQGNWVVKSDVLYPKNTCSSHSGVPAEVLCRGRDFVMWRFTIERTLMRKEVAAIIKLPPEDVKDFLEQMSVPRLNRGWEFLLPTDQDFVKKHPDVAQRQHMLWTGIQSKLEKVFNFSKDDFVHKKDVQMEPVHLSGDQRLKAAQENAQEKHSILQRELDAHRLKASRLSGSQGPSGASVTVKQEPVSDSEEPMDTGAALTNGSVNGYPAASSPTSDPHNGHGQAFTPELQDFVKNTFRKHYVLCLSEVKRLFNLHLASLPSGHAAYGHVTDRMLQDTILHSHCKQILVPFPPQSSAAADEQKVFGLWESGETFDKLRQILFEIFMKNYRVRRNVIQTRLTQELGDAVNKTDVDRLLKECCISLGGMWYLKGTVHS", "length": 696 }, "evidence": [ { "id": "A0A8V0Z9L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CZT4-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5", "gene_name": "Polr3e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSAPVGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGAELEAEEEEPMDTAPSTCLSTKLANGLPAGRAVGGDSLNGHPVPGCASNPVACELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHILFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNLIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "length": 710 }, "evidence": [ { "id": "A0A8V0Z9L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVU0-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5", "gene_name": "POLR3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANEEDDPVVQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTSRYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEDDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGLRDSRSEHERQYLLCPGSSGVENTELVKSPSEYLMMLMPPSQEEEKDKPVAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGPSIDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGVPAEVLCRGRDFVMWKFTQSRWVVRKEVATVTKLCAEDVKDFLEHMAVVRINKGWEFILPYDGEFIKKHPDVVQRQHMLWTGIQAKLEKVYNLVKETMPKKPDAQSGPAGLVCGDQRIQVAKTKAQQNHALLERELQRRKEQLRVPAVPPGVRIKEEPVSEEGEEDEEQEAEEEPMDTSPSGLHSKLANGLPLGRAAGTDSFNGHPPQGCASTPVARELKAFVEATFQRQFVLTLSELKRLFNLHLASLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEDLSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 708 }, "evidence": [ { "id": "A0A8V0Z9L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L9" }, { "id": "PF19725", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19725" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA-directed RNA polymerase III subunit RPC5 C-terminal", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 714, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 506, "end_pos": 508 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9C2-1", "uniprot_ac": "A0A8V0Z9C2", "uniprot_id": "A0A8V0Z9C2_CHICK", "mass": { "chemical_mass": 32916.0, "monoisotopic_mass": 32916.0 }, "refseq": { "ac": "XP_040554996", "name": "max dimerization protein 4 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554996" }, "gene_names": [ { "name": "MXD4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C2" } ] }, { "name": "MXD4", "type": "synonym", "evidence": [ { "id": "XP_040554996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554996" } ] } ], "protein_names": [ { "name": "MAX dimerization protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C2/entry#names_and_taxonomy" } ] }, { "name": "max dimerization protein 4 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040554996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040554996.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040554996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MXD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C2", "locus": { "chromosome": "4", "start_pos": 82388985, "end_pos": 82351018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017600", "url": "https://www.ensembl.org/id/ENSGALG00010017600" } ] } } ], "crossref": [ { "id": "A0A8V0Z9C2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015688", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015688", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422890", "url": "https://www.ncbi.nlm.nih.gov/gene/422890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2A0", "url": "https://www.orthodb.org/?gene=A0A8V0Z2A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9C2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6U2D7", "url": "https://www.orthodb.org/?gene=F6U2D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040554996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040554996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2A0-1", 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"https://www.uniprot.org/uniprotkb/A0A8V0Z9C2/entry#F6U2D7-1", "sequence": { "sequence": "MELNSLLILLEAAEYLERRDRAFLQRRKKMHGKNILPLMLTLSLEAEHGYASVLPFDSDYSRKKTKAGSMARKSPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKMHIKKLEEQDRKALNIKEQLQREHRYLKRRLEQLSVQGMERIRTDSMGSTISTDSEQEVDIEGMEFTPGEMDSIGSASDAEDHYSLQSGSSDGGYSHSRRLNARLS", "length": 228, "header": "tr|F6U2D7-1|A0A8V0Z9C2_CHICK Computationally mapped isoform of MAX dimerization protein 4 OS=Gallus gallus OX=9031 GN=MXD4 PE=4 SV=1 CANONICAL=A0A8V0Z9C2-1" }, "locus": { "chromosome": "4", "start_pos": 82386326, "end_pos": 82351606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042551.1", "url": "https://www.ensembl.org/id/ENSGALT00010042551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025041.1", "url": "https://www.ensembl.org/id/ENSGALP00010025041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC2A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2", "locus": { "chromosome": "21", "start_pos": 3234631, "end_pos": 3247424, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017402", "url": "https://www.ensembl.org/id/ENSGALG00010017402" } ] } } ], "crossref": [ { "id": "A0A8V0Z7Z2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7Z2", "database": 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"F1NVV4", "url": "https://www.orthodb.org/?gene=F1NVV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8981373", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8981373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004947503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60372", "url": "https://www.rhea-db.org/rhea/60372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVV4", "url": "https://www.uniprot.org/uniprotkb/F1NVV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVV4-1", "url": "https://www.uniprot.org/uniprotkb/F1NVV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPMEKGLDGSQSKLSGPNPRMTLPLALVTLISAFGSSFQYGYNVSVINSPAPYMQDFYNRTYIDRHGVPMDASFQTLLWSLTVSMYPLGGFFGSLMVGPLVNNCGRKGTLLINNLFSIVAAVLMGTSEVAKTFEVIIVSRVIMGIYAGLASNVVPMFLGEMSPRNLRGAIGIVPQLFITLGILIAQILGLTSILGHVKGWPLLLGLTGIPSALQLLTLPFFPESPRYLLIQKGNEDEARQALQRLRGWDDVDDEIEEMRQEDKSEKEEGHLSVFTLCTFRGLRWQLISIVVMMMGQQLSGINAVFYYADRIFLSAGVETDHVQYVTVSIGAINVLMTLLAVFIVESLGRRILLLAGFGLCCGSCAVLTLALNLQNTVSWMSYLSIVCVIIYIIGHAIGASPIPFVMITEMFLQSSRPAAFMVGGSVHWLCNFTVGLVFLYMEAGLGAYSFLIFCGICLATMVYIFFIVPETKNKTFMEINRIMAKRNKVEIQTDVEQMMDLQTVPSVKADKSEVLGSDL", "length": 519, "header": "tr|A0A8V0Z7Z2-1|A0A8V0Z7Z2_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=SLC2A5 PE=1 SV=1 CANONICAL=A0A8V0Z7Z2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2/entry#A0A8V0Z2A8-1", "sequence": { "sequence": "MQPRMTLPLALVTLISAFGSSFQYGYNVSVINSPAPYMQDFYNRTYIDRHGVPMDASFQTLLWSLTVSMYPLGGFFGSLMVGPLVNNCGRKGTLLINNLFSIVAAVLMGTSEVAKTFEVIIVSRVIMGIYAGLASNVVPMFLGEMSPRNLRGAIGIVPQLFITLGILIAQILGLTSILGHVKGWPLLLGLTGIPSALQLLTLPFFPESPRYLLIQKGNEDEARQALQRLRGWDDVDDEIEEMRQEDKSEKEEGHLSVFTLCTFRGLRWQLISIVVMMMGQQLSGINAVFYYADRIFLSAGVETDHVQYVTVSIGAINVLMTLLAVFIVESLGRRILLLAGFGLCCGSCAVLTLALNLQNTVSWMSYLSIVCVIIYIIGHAIGASPIPFVMITEMFLQSSRPAAFMVGGSVHWLCNFTVGLVFLYMEAGLGAYSFLIFCGICLATMVYIFFIVPETKNKTFMEINRIMAKRNKVEIQTDVEQMMDLQTVPSVKADKSEVLGSDL", "length": 503, "header": "tr|A0A8V0Z2A8-1|A0A8V0Z7Z2_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=SLC2A5 PE=1 SV=1 CANONICAL=A0A8V0Z7Z2-1" }, "locus": { "chromosome": "21", "start_pos": 3242428, "end_pos": 3236074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041992.1", "url": "https://www.ensembl.org/id/ENSGALT00010041992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024579.1", "url": "https://www.ensembl.org/id/ENSGALP00010024579.1" } ] } }, { "isoform_ac": "A0A8V0Z7Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2/entry#A0A8V0Z7Z2-1", "sequence": { "sequence": "MPMEKGLDGSQSKLSGPNPRMTLPLALVTLISAFGSSFQYGYNVSVINSPAPYMQDFYNRTYIDRHGVPMDASFQTLLWSLTVSMYPLGGFFGSLMVGPLVNNCGRKGTLLINNLFSIVAAVLMGTSEVAKTFEVIIVSRVIMGIYAGLASNVVPMFLGEMSPRNLRGAIGIVPQLFITLGILIAQILGLTSILGHVKGWPLLLGLTGIPSALQLLTLPFFPESPRYLLIQKGNEDEARQALQRLRGWDDVDDEIEEMRQEDKSEKEEGHLSVFTLCTFRGLRWQLISIVVMMMGQQLSGINAVFYYADRIFLSAGVETDHVQYVTVSIGAINVLMTLLAVFIVESLGRRILLLAGFGLCCGSCAVLTLALNLQNTVSWMSYLSIVCVIIYIIGHAIGASPIPFVMITEMFLQSSRPAAFMVGGSVHWLCNFTVGLVFLYMEAGLGAYSFLIFCGICLATMVYIFFIVPETKNKTFMEINRIMAKRNKVEIQTDVEQMMDLQTVPSVKADKSEVLGSDL", "length": 519, "header": "tr|A0A8V0Z7Z2-1|A0A8V0Z7Z2_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=SLC2A5 PE=1 SV=1 CANONICAL=A0A8V0Z7Z2-1" }, "locus": { "chromosome": "21", "start_pos": 3246890, "end_pos": 3236074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041998.1", "url": "https://www.ensembl.org/id/ENSGALT00010041998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024582.1", "url": "https://www.ensembl.org/id/ENSGALP00010024582.1" } ] } }, { "isoform_ac": "F1NVV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2/entry#F1NVV4-1", "sequence": { "sequence": "MEMNGEKQESSSVEEGRKGRMTLPLALVTLISAFGSSFQYGYNVSVINSPAPYMQDFYNRTYIDRHGVPMDASFQTLLWSLTVSMYPLGGFFGSLMVGPLVNNCGRKGTLLINNLFSIVAAVLMGTSEVAKTFEVIIVSRVIMGIYAGLASNVVPMFLGEMSPRNLRGAIGIVPQLFITLGILIAQILGLTSILGHVKGWPLLLGLTGIPSALQLLTLPFFPESPRYLLIQKGNEDEARQALQRLRGWDDVDDEIEEMRQEDKSEKEEGHLSVFTLCTFRGLRWQLISIVVMMMGQQLSGINAVFYYADRIFLSAGVETDHVQYVTVSIGAINVLMTLLAVFIVESLGRRILLLAGFGLCCGSCAVLTLALNLQNTVSWMSYLSIVCVIIYIIGHAIGASPIPFVMITEMFLQSSRPAAFMVGGSVHWLCNFTVGLVFLYMEAGLGAYSFLIFCGICLATMVYIFFIVPETKNKTFMEINRIMAKRNKVEIQTDVEQMMDLQTVPSVKADKSEVLGSDL", "length": 519, "header": "tr|F1NVV4-1|A0A8V0Z7Z2_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 5 OS=Gallus gallus OX=9031 GN=SLC2A5 PE=1 SV=2 CANONICAL=A0A8V0Z7Z2-1" }, "locus": { "chromosome": "21", "start_pos": 3243713, "end_pos": 3236074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041996.1", "url": "https://www.ensembl.org/id/ENSGALT00010041996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024581.1", "url": "https://www.ensembl.org/id/ENSGALP00010024581.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419438", "resource": "KEGG Pathway" }, { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8981373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8981373", "resource": "Reactome", "description": "Intestinal hexose absorption" } ], "orthologs": [ { "uniprot_canonical_ac": "P22732-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 5", "gene_name": "SLC2A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEKEELKELPPVTSEQ", "length": 501 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P39003-1", "protein_name": "High-affinity hexose transporter HXT6", "gene_name": "HXT6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQDAAIAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK", "length": 570 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43427-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 5", "gene_name": "Slc2a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKEDQEKTGKLTLVLALATFLAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNKENIESFTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKIAKSFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLRSVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWKDVDMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYADQIYLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIGFSTCLTACIVLTVALALQNTISWMPYVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWLSNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIFAKKNKVSDVYPEKEEKELNDLPPATREQ", "length": 502 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58353-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 5", "gene_name": "SLC2A5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPQDPVKREGRLTPVIVLATLIAAFGSSFQYGYNVAAINSPSEFMKDFYNYTYYDRVGEYMNEFYLTLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSELAKSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIFGLRSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGWHDVDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYADQIYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLTGALALQDVISWMPYVSIACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMVAGTVHWLSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINRIFIKMNKVPGVHPEKEELKEFPPSTARQ", "length": 501 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3ECP7-1", "protein_name": "Sugar transporter ERD6-like 5", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRGEIDEANLAPETSLINKENQDSSATITTTLLLTTFVAVSGSFVFGSAIGYSSPVQSDLTKELNLSVAEYSLFGSILTIGAMIGAAMSGRIADMIGRRATMGFSEMFCILGWLAIYLSKVAIWLDVGRFLVGYGMGVFSFVVPVYIAEITPKGLRGGFTTVHQLLICLGVSVTYLLGSFIGWRILALIGMIPCVVQMMGLFVIPESPRWLAKVGKWEEFEIALQRLRGESADISYESNEIKDYTRRLTDLSEGSIVDLFQPQYAKSLVVGVGLMVLQQFGGVNGIAFYASSIFESAGVSSKIGMIAMVVVQIPMTTLGVLLMDKSGRRPLLLISATGTCIGCFLVGLSFSLQFVKQLSGDASYLALTGVLVYTGSFSLGMGGIPWVIMSEIFPIDIKGSAGSLVTVVSWVGSWIISFTFNFLMNWNPAGTFYVFATVCGATVIFVAKLVPETKGRTLEEIQYSIGYVEL", "length": 470 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WV38-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 5", "gene_name": "Slc2a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKHQEETGELTLVLALATLIAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNEENIESFTLTLLWSLTVSMFPFGGFIGSLMVGTLVNKLGRKGALLFNNIFSILPAILMGCSQIAQSFELIIISRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLRSLLANEDGWPVLLGLTGVPAGLQLLLLPFFPESPRYLLIQKKDEAAAERALQTLRGWKDVHLEMEEIRKEDEAEKAAGFISVWKLFTMQSLRWQLISMIVLMAGQQLSGVNAIYYYADQIYLSAGVKSDDVQYVTAGTGAVNVFMTILTIFVVELWGRRFLLLVGFSTCLIACLVLTAALALQNTISWMPYISIVCVIVYVIGHALGPSPIPALLITEIFLQSSRPAAYMIGGSVHWLSNFTVGLIFPFIQMGLGPYSFIIFATICFLTTIYIFMVVPETKGRTFIEINQIFTMKNKVSDVYPKKEEELGALPHAILEQ", "length": 501 }, "evidence": [ { "id": "A0A8V0Z7Z2", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "fructose import across plasma membrane", "id": "GO:1990539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "dehydroascorbic acid transport", "id": "GO:0070837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "regulation of systemic arterial blood pressure mediated by a chemical signal", "id": "GO:0003044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" }, { "name": "cellular response to fructose stimulus", "id": "GO:0071332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60372", "name": "", "equation": "D-fructose(out) = D-fructose(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60372", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60372" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 472, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z893-1", "uniprot_ac": "A0A8V0Z893", "uniprot_id": "A0A8V0Z893_CHICK", "mass": { "chemical_mass": 24740.0, "monoisotopic_mass": 24740.0 }, "refseq": {}, "gene_names": [ { "name": "RYBP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z893", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ] } ], "protein_names": [ { "name": "RING1 and YY1 binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z893", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RYBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893", "locus": { "chromosome": "12", "start_pos": 16579647, "end_pos": 16614464, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018991", "url": "https://www.ensembl.org/id/ENSGALG00010018991" } ] } } ], "crossref": [ { "id": "A0A8V0Z893", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z893", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033025", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033025", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416095", "url": "https://www.ncbi.nlm.nih.gov/gene/416095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416095", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEREHGP", "url": "https://omabrowser.org/oma/group/PEREHGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PYG9", "url": "https://www.orthodb.org/?gene=A0A1D5PYG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2E2", "url": "https://www.orthodb.org/?gene=A0A8V0Z2E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z893", "url": "https://www.orthodb.org/?gene=A0A8V0Z893", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z898", "url": "https://www.orthodb.org/?gene=A0A8V0Z898", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9S1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12920:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12920:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PYG9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PYG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z893-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z898", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z898", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z898-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z898-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9S1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9S1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RFLGCICGLKRTGNLHGCAESAITQPAFKVIVKLHHKQQLPDLCEEGDFFFQKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 227, "header": "tr|A0A8V0Z893-1|A0A8V0Z893_CHICK Isoform 1 of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#A0A1D5PYG9-1", "sequence": { "sequence": "MVMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228, "header": "tr|A0A1D5PYG9-1|A0A8V0Z893_CHICK Computationally mapped isoform of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "locus": { "chromosome": "12", "start_pos": 16614240, "end_pos": 16583318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045972.1", "url": "https://www.ensembl.org/id/ENSGALT00010045972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027389.1", "url": "https://www.ensembl.org/id/ENSGALP00010027389.1" } ] } }, { "isoform_ac": "A0A8V0Z2E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#A0A8V0Z2E2-1", "sequence": { "sequence": "VSSVQSVFFLLPTERSSWFWCYSTVVLFLLLLTWTKKTAFLLLICVCAFARRAGRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 230, "header": "tr|A0A8V0Z2E2-1|A0A8V0Z893_CHICK Computationally mapped isoform of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "locus": { "chromosome": "12", "start_pos": 16602728, "end_pos": 16583318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045965.1", "url": "https://www.ensembl.org/id/ENSGALT00010045965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027385.1", "url": "https://www.ensembl.org/id/ENSGALP00010027385.1" } ] } }, { "isoform_ac": "A0A8V0Z893-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#A0A8V0Z893-1", "sequence": { "sequence": "RFLGCICGLKRTGNLHGCAESAITQPAFKVIVKLHHKQQLPDLCEEGDFFFQKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 227, "header": "tr|A0A8V0Z893-1|A0A8V0Z893_CHICK Isoform 1 of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "locus": { "chromosome": "12", "start_pos": 16603787, "end_pos": 16583318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045960.1", "url": "https://www.ensembl.org/id/ENSGALT00010045960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027382.1", "url": "https://www.ensembl.org/id/ENSGALP00010027382.1" } ] } }, { "isoform_ac": "A0A8V0Z898-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#A0A8V0Z898-1", "sequence": { "sequence": "MPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 218, "header": "tr|A0A8V0Z898-1|A0A8V0Z898_CHICK Computationally mapped isoform of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "locus": { "chromosome": "12", "start_pos": 16613483, "end_pos": 16583318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045970.1", "url": "https://www.ensembl.org/id/ENSGALT00010045970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027387.1", "url": "https://www.ensembl.org/id/ENSGALP00010027387.1" } ] } }, { "isoform_ac": "A0A8V0Z9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893/entry#A0A8V0Z9S1-1", "sequence": { "sequence": "DGGRECGRGGPASPRRQVRDSGGRRLRWRERGAGGGRRRRRRRRRRRSVRGSPRRCRADLVPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPDKEKEISPSVTKKNTNKKTKPKSDIVKDPPSEANSIQSGNTTTKTSDSNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 278, "header": "tr|A0A8V0Z9S1-1|A0A8V0Z9S1_CHICK Computationally mapped isoform of RING1 and YY1 binding protein OS=Gallus gallus OX=9031 GN=RYBP PE=4 SV=1 CANONICAL=A0A8V0Z893-1" }, "locus": { "chromosome": "12", "start_pos": 16614035, "end_pos": 16583318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045971.1", "url": "https://www.ensembl.org/id/ENSGALT00010045971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027388.1", "url": "https://www.ensembl.org/id/ENSGALP00010027388.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416095", "resource": "KEGG Pathway" }, { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-GGA-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "resource": "Reactome", "description": "Transcriptional Regulation by E2F6" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M3Z6-1", "protein_name": "RING1 and YY1 binding protein", "gene_name": "LOC120102351", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRGARPRPSSVTRRRRRWRGLVSSGDWRRRQRRRRRRRRLELEPSGGGRAGGAGGRGPLRDAADRASPLSGGARSCGAPGASPSMTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 313 }, "evidence": [ { "id": "A0A8V0Z893", "url": "https://omabrowser.org/oma/group/A0A8V0Z893/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SFN1-1", "protein_name": "RING1 and YY1 binding protein", "gene_name": "RYBP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228 }, "evidence": [ { "id": "A0A8V0Z893", "url": "https://omabrowser.org/oma/group/A0A8V0Z893/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CCI5-1", "protein_name": "RING1 and YY1-binding protein", "gene_name": "Rybp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228 }, "evidence": [ { "id": "A0A8V0Z893", "url": "https://omabrowser.org/oma/group/A0A8V0Z893/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N488-1", "protein_name": "RING1 and YY1-binding protein", "gene_name": "RYBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228 }, "evidence": [ { "id": "A0A8V0Z893", "url": "https://omabrowser.org/oma/group/A0A8V0Z893/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z893", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z893" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 161 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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56711.0, "monoisotopic_mass": 56711.0 }, "refseq": { "ac": "XP_040539997", "name": "transmembrane protein 180 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539997" }, "gene_names": [ { "name": "LOC416622", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1" } ] }, { "name": "LOC416622", "type": "synonym", "evidence": [ { "id": "XP_040539997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539997" } ] } ], "protein_names": [ { "name": "Transmembrane protein 180", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 180 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040539997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539997" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052586.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040539997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539997" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC416622", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z8X1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8X1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007030", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007030", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416622", "url": "https://www.ncbi.nlm.nih.gov/gene/416622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2G5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B8", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8W6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8X1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGH8", "url": "https://www.orthodb.org/?gene=F1NGH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28658:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28658:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040539997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539997", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2G5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGH8", "url": "https://www.uniprot.org/uniprotkb/F1NGH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGH8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRPPGRSKGAPANRKASSWQATNEREGEEEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 505, "header": "tr|A0A8V0Z8X1-1|A0A8V0Z8X1_CHICK Isoform 1 of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#A0A8V0Z2G5-1", "sequence": { "sequence": "MWIHGFKITRCLSEEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 488, "header": "tr|A0A8V0Z2G5-1|A0A8V0Z8X1_CHICK Computationally mapped isoform of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8738606, "end_pos": 8726091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045999.1", "url": "https://www.ensembl.org/id/ENSGALT00010045999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027405.1", "url": "https://www.ensembl.org/id/ENSGALP00010027405.1" } ] } }, { "isoform_ac": "A0A8V0Z8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#A0A8V0Z8B8-1", "sequence": { "sequence": "MTFNAVTSLYARGSTEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 487, "header": "tr|A0A8V0Z8B8-1|A0A8V0Z8B8_CHICK Computationally mapped isoform of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8738606, "end_pos": 8724152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046001.1", "url": "https://www.ensembl.org/id/ENSGALT00010046001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027407.1", "url": "https://www.ensembl.org/id/ENSGALP00010027407.1" } ] } }, { "isoform_ac": "A0A8V0Z8W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#A0A8V0Z8W6-1", "sequence": { "sequence": "MVLEEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSAIKKVCSLKTPSSGDLLQQQLTSTNLLFQFVLQ", "length": 469, "header": "tr|A0A8V0Z8W6-1|A0A8V0Z8W6_CHICK Computationally mapped isoform of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8736498, "end_pos": 8725853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045998.1", "url": "https://www.ensembl.org/id/ENSGALT00010045998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027404.1", "url": "https://www.ensembl.org/id/ENSGALP00010027404.1" } ] } }, { "isoform_ac": "A0A8V0Z8X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#A0A8V0Z8X1-1", "sequence": { "sequence": "MGSRPPGRSKGAPANRKASSWQATNEREGEEEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 505, "header": "tr|A0A8V0Z8X1-1|A0A8V0Z8X1_CHICK Isoform 1 of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8738606, "end_pos": 8724844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046003.1", "url": "https://www.ensembl.org/id/ENSGALT00010046003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027409.1", "url": "https://www.ensembl.org/id/ENSGALP00010027409.1" } ] } }, { "isoform_ac": "A0A8V0ZFR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#A0A8V0ZFR7-1", "sequence": { "sequence": "MVLEEEAHAVGKMKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 478, "header": "tr|A0A8V0ZFR7-1|A0A8V0ZFR7_CHICK Computationally mapped isoform of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=1 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8738606, "end_pos": 8725853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046000.1", "url": "https://www.ensembl.org/id/ENSGALT00010046000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027406.1", "url": "https://www.ensembl.org/id/ENSGALP00010027406.1" } ] } }, { "isoform_ac": "F1NGH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1/entry#F1NGH8-1", "sequence": { "sequence": "MKLALEIHPNALAYSMTTLGAGMMNSVFNFYYVKLFLNRYRISEVAFHQAQVVFMIWNAINDPLFGYIQDNSKLPCCSRRQFSILYGAPLYALAFLLPWFPWRHYEEGDWLSGLHLIIALCAFDGLLTFVLLAQCALFAEISTRHESRLQLIKYNQVATLIGSTSVLFCGLISDNMENFAYFQAFAVLIAALATACMYYTGKYSTSQYEQRGIPAENADRGNGDRALSWSSVISLTKQIMTEKNFVFFVTMNFFQVFHLAFCNNFMMIFADNLIPKDVLSSSLRSIMYGAGFICPQCLVLLSHASLKKFGYYRIILFSFYFEGVAAAVMFVLGPGHYHLLAFYLTTNMVIVQASFSLFNLPLADIVDADLIKHKRRSPLSSMVFGTNALFTKPAQSLAPMLVVTILNQFGYENLNNEVAQPDPSLFLGLHDAMFYLVCLVPLCIAVVQILTWTPFSIQNSHMTAAH", "length": 466, "header": "tr|F1NGH8-1|A0A8V0Z8X1_CHICK Computationally mapped isoform of Transmembrane protein 180 OS=Gallus gallus OX=9031 GN=LOC416622 PE=4 SV=4 CANONICAL=A0A8V0Z8X1-1" }, "locus": { "chromosome": "14", "start_pos": 8738606, "end_pos": 8727525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045992.1", "url": "https://www.ensembl.org/id/ENSGALT00010045992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027401.1", "url": "https://www.ensembl.org/id/ENSGALP00010027401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9I4-1", "uniprot_ac": "A0A8V0Z9I4", "uniprot_id": "A0A8V0Z9I4_CHICK", "mass": { "chemical_mass": 58660.0, "monoisotopic_mass": 58660.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Coiled-coil domain-containing protein 30", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9I4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9I4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR031476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34479", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34479", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34479:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34479:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z2G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRENADQQSLSEERFQQQEERLQQLRHDLRRVQNLCSSAERELRYEREKNIDLQKQNLLLQQECTKVKAELKQARTKLLDSTETCSSLSAQWEKSQQKVKELEQELLKCSQADKLQSSLQEKLVQEKSKVYEAQKQISKIQQKLKDSQHQLLLAEARVSDKKLLEEELKEARENEARVQQELREELLKRKLLEQQVEELRQQLRHSHETEASLAKMHVELQAKTLHALEDDKKTDSGEHLQCQKESQKLSEQLSLLKEENKALYEEGVRLLNQKDLYVRKYNEMQLRHKEKIRRAKATFIHEVKQRDSRIKQLENELSESKLQVEKGKALIAQITTENEKLLQERRRLLQRITDQEETPWSNRSTVAALQSRMKILDEENMRLHESKLHLSGHMHTSQRTLRSIHTPSTEDLKSANFSERQLQSKVSASSPRASFPPREPPDSLSSLKPVHDTKPEGGAESQDSSFCLSPSQPSEIGYLNVASPGDTTASQLQEESQSISSENF", "length": 505, "header": "tr|A0A8V0Z9I4-1|A0A8V0Z9I4_CHICK Isoform 1 of Coiled-coil domain-containing protein 30 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9I4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4/entry#A0A8V0Z2G8-1", "sequence": { "sequence": "WQNWNGSQSLKGCRTDIKGELRNRLPWSLSEERFQQQEERLQQLRHDLRRVQNLCSSAERELRYEREKNIDLQKQNLLLQQECTKVKAELKQARTKLLDSTETCSSLSAQWEKSQQKVKELEQELLKCSQADKLQSSLQEKLVQEKSKVYEAQKQISKIQQKLKDSQHQLLLAEARVSDKKLLEEELKEARENEARVQQELREELLKRKLLEQQVEELRQQLRHSHETEASLAKMHVELQAKTLHALEDDKKTDSGEHLQCQKESQKLSEQLSLLKEENKALYEEGVRLLNQKDLYVRKYNEMQLRHKEKIRRAKATFIHEVKQRDSRIKQLENELSESKLQVEKVKELIGGFPYREGREADCRLSLLPAMRRLPQ", "length": 376, "header": "tr|A0A8V0Z2G8-1|A0A8V0Z9I4_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 30 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9I4-1" }, "locus": { "chromosome": "21", "start_pos": 6408012, "end_pos": 6404004, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042623.1", "url": "https://www.ensembl.org/id/ENSGALT00010042623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025113.1", "url": "https://www.ensembl.org/id/ENSGALP00010025113.1" } ] } }, { "isoform_ac": "A0A8V0Z9I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I4/entry#A0A8V0Z9I4-1", "sequence": { "sequence": "MGRENADQQSLSEERFQQQEERLQQLRHDLRRVQNLCSSAERELRYEREKNIDLQKQNLLLQQECTKVKAELKQARTKLLDSTETCSSLSAQWEKSQQKVKELEQELLKCSQADKLQSSLQEKLVQEKSKVYEAQKQISKIQQKLKDSQHQLLLAEARVSDKKLLEEELKEARENEARVQQELREELLKRKLLEQQVEELRQQLRHSHETEASLAKMHVELQAKTLHALEDDKKTDSGEHLQCQKESQKLSEQLSLLKEENKALYEEGVRLLNQKDLYVRKYNEMQLRHKEKIRRAKATFIHEVKQRDSRIKQLENELSESKLQVEKGKALIAQITTENEKLLQERRRLLQRITDQEETPWSNRSTVAALQSRMKILDEENMRLHESKLHLSGHMHTSQRTLRSIHTPSTEDLKSANFSERQLQSKVSASSPRASFPPREPPDSLSSLKPVHDTKPEGGAESQDSSFCLSPSQPSEIGYLNVASPGDTTASQLQEESQSISSENF", "length": 505, "header": "tr|A0A8V0Z9I4-1|A0A8V0Z9I4_CHICK Isoform 1 of Coiled-coil domain-containing protein 30 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9I4-1" }, "locus": { "chromosome": "21", "start_pos": 6407482, "end_pos": 6400106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042626.1", "url": "https://www.ensembl.org/id/ENSGALT00010042626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025115.1", "url": "https://www.ensembl.org/id/ENSGALP00010025115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z908-1", "uniprot_ac": "A0A8V0Z908", "uniprot_id": "A0A8V0Z908_CHICK", "mass": { "chemical_mass": 46778.0, "monoisotopic_mass": 46778.0 }, "refseq": { "ac": "XP_004935377", "name": "potassium channel subfamily K member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935377" }, "gene_names": [ { "name": "KCNK2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z908", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908" } ] }, { "name": "KCNK2", "type": "synonym", "evidence": [ { "id": "XP_004935377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935377" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z908", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935377" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935377" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z908", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908", "locus": { "chromosome": "3", "start_pos": 20526515, "end_pos": 20653070, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019020", "url": "https://www.ensembl.org/id/ENSGALG00010019020" } ] } } ], "crossref": [ { "id": "A0A8V0Z908", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z908", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009687", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009687", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770954", "url": "https://www.ncbi.nlm.nih.gov/gene/770954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770954", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANLCEDR", "url": "https://omabrowser.org/oma/group/ANLCEDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2K0", "url": "https://www.orthodb.org/?gene=A0A8V0Z2K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z908", "url": "https://www.orthodb.org/?gene=A0A8V0Z908", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZ45", "url": "https://www.orthodb.org/?gene=F1NZ45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1299503", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299503", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004935377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z908", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z908-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ45", "url": "https://www.uniprot.org/uniprotkb/F1NZ45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ45-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNPQARHNFYLAAPDLLDPKSATQNSKPRLSFSTKPTVLSSREESDSAINVMKWKTVSTIFLVVVVYLIIGATVFKALEQPHETSQRATIVIQKQTFVSQHSCVNATELDELIQQVVAAINAGIIPLGNTSTQISHWDLGSSFFFAGTVITTIGFGNISPRTQGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFVKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSTLDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAVNHNQDLTPCKRTLSVNHLTSEKDLLPALTKTDSIYMNGLTPHCAAEEIAVIENIK", "length": 422, "header": "tr|A0A8V0Z908-1|A0A8V0Z908_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 2 OS=Gallus gallus OX=9031 GN=KCNK2 PE=3 SV=1 CANONICAL=A0A8V0Z908-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908/entry#A0A8V0Z2K0-1", "sequence": { "sequence": "MRNPQARHNFYLAAPDLLDPKSATQNSKPRLSFSTKPTVLSSREESDSAINVMKWKTVSTIFLVVVVYLIIGATVFKALEQPHETSQRATIVIQKQTFVSQHSCVNATELDELIQALETSPHAHKVERYSVSSMPYWEFLCLVFSWLVLEIN", "length": 152, "header": "tr|A0A8V0Z2K0-1|A0A8V0Z908_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 2 OS=Gallus gallus OX=9031 GN=KCNK2 PE=3 SV=1 CANONICAL=A0A8V0Z908-1" }, "locus": { "chromosome": "3", "start_pos": 20630659, "end_pos": 20554041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046039.1", "url": "https://www.ensembl.org/id/ENSGALT00010046039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027436.1", "url": "https://www.ensembl.org/id/ENSGALP00010027436.1" } ] } }, { "isoform_ac": "A0A8V0Z908-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908/entry#A0A8V0Z908-1", "sequence": { "sequence": "MRNPQARHNFYLAAPDLLDPKSATQNSKPRLSFSTKPTVLSSREESDSAINVMKWKTVSTIFLVVVVYLIIGATVFKALEQPHETSQRATIVIQKQTFVSQHSCVNATELDELIQQVVAAINAGIIPLGNTSTQISHWDLGSSFFFAGTVITTIGFGNISPRTQGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFVKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSTLDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAVNHNQDLTPCKRTLSVNHLTSEKDLLPALTKTDSIYMNGLTPHCAAEEIAVIENIK", "length": 422, "header": "tr|A0A8V0Z908-1|A0A8V0Z908_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 2 OS=Gallus gallus OX=9031 GN=KCNK2 PE=3 SV=1 CANONICAL=A0A8V0Z908-1" }, "locus": { "chromosome": "3", "start_pos": 20630659, "end_pos": 20528647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046043.1", "url": "https://www.ensembl.org/id/ENSGALT00010046043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027440.1", "url": "https://www.ensembl.org/id/ENSGALP00010027440.1" } ] } }, { "isoform_ac": "F1NZ45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z908/entry#F1NZ45-1", "sequence": { "sequence": "MAAPDLLDPKSATQNSKPRLSFSTKPTVLSSREESDSAINVMKWKTVSTIFLVVVVYLIIGATVFKALEQPHETSQRATIVIQKQTFVSQHSCVNATELDELIQQVVAAINAGIIPLGNTSTQISHWDLGSSFFFAGTVITTIGFGNISPRTQGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFVKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSTLDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAVNHNQDLTPCKRTLSVNHLTSEKDLLPALTKTDSIYMNGLTPHCAAEEIAVIENIK", "length": 411, "header": "tr|F1NZ45-1|A0A8V0Z908_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 2 OS=Gallus gallus OX=9031 GN=KCNK2 PE=3 SV=4 CANONICAL=A0A8V0Z908-1" }, "locus": { "chromosome": "3", "start_pos": 20601517, "end_pos": 20528647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046034.1", "url": "https://www.ensembl.org/id/ENSGALT00010046034.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027431.1", "url": "https://www.ensembl.org/id/ENSGALP00010027431.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770954", "resource": "KEGG Pathway" }, { "id": "R-GGA-1299503", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299503", "resource": "Reactome", "description": "TWIK related potassium channel (TREK)" }, { "id": "R-GGA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "F6QTJ5-1", "protein_name": "Potassium two pore domain channel subfamily K member 2", "gene_name": "KCNK2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPSASRERTGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 426 }, "evidence": [ { "id": "A0A8V0Z908", "url": "https://omabrowser.org/oma/group/A0A8V0Z908/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95069-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "KCNK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 426 }, "evidence": [ { "id": "A0A8V0Z908", "url": "https://omabrowser.org/oma/group/A0A8V0Z908/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97438-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "Kcnk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLASASRERPGYTAGVAAPDLLDPKSAAQNSKPRLSFSSKPTVLASRVESDSAINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQKQTFIAQHACVNSTELDELIQQIVAAINAGIIPLGNSSNQVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSVKRKLSAELAGNHNQELTPCRRTLSVNHLTSEREVLPPLLKAESIYLNGLTPHCAGEDIAVIENMK", "length": 426 }, "evidence": [ { "id": "A0A8V0Z908", "url": "https://omabrowser.org/oma/group/A0A8V0Z908/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920B6-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "Kcnk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"A0A8V0Z2L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVPWLLLASALLLPPGGAADPLPTLAPPLTMMVSGQWRRLVVCVVSELPASSGHAVWISSGNGSALQSFAYGASQEEGGTVCAVSILPDSPMEQELLACHVGPNSSAPAHSSSPIAVAGTDTGPAREQGCSSRRVALWVNVTQGQEGGCGSPFPAVPHPAGSDEEAELCPSTPAVCKYVALELKSAFEETGKTKEVIDTKYGFLDGKGAAVKYTQSDIRLIEVTENICKRLLDYNLHKERSGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEYEDVIEDWYRHHQTEDLSQFLCADRVLKGKDASCLAEKWTGKKGDLASAGEKPSKKKSGKKKKKEGKEQSEGARSLPEEESGVQEAAPLPHSPTDEL", "length": 394, "header": "tr|A0A8V0Z9Y3-1|A0A8V0Z9Y3_CHICK Isoform 1 of Protein canopy homolog 3 OS=Gallus gallus OX=9031 GN=CNPY3 PE=1 SV=1 CANONICAL=A0A8V0Z9Y3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3/entry#A0A8V0Z2K8-1", "sequence": { "sequence": "MGPTVRWDVEGPSATGPRQASRGGGVYSAGRAVIGRAGRAVIGRAGRAVIGRACHAGRWGWWRRRVAVATGAERRPGSGAMAAEGPAALLLLLLVAVAGGDDADWVRLPSKCEVCKYVALELKSAFEETGKTKEVIDTKYGFLDGKGAAVKYTQSDIRLIEVTENICKRLLDYNLHKERSGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEYEDVIEDWYRHHQTEDLSQFLCADRVLKGKDASCLAEKWTGKKGDLASAGEKPSKKKSGKKKKKEGKEQSEGARSLPEEESGVQEAAPLPHSPTDEL", "length": 332, "header": "tr|A0A8V0Z2K8-1|A0A8V0Z9Y3_CHICK Computationally mapped isoform of Protein canopy homolog 3 OS=Gallus gallus OX=9031 GN=CNPY3 PE=1 SV=1 CANONICAL=A0A8V0Z9Y3-1" }, "locus": { "chromosome": "3", "start_pos": 15729765, "end_pos": 15727204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046052.1", "url": "https://www.ensembl.org/id/ENSGALT00010046052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027446.1", "url": "https://www.ensembl.org/id/ENSGALP00010027446.1" } ] } }, { "isoform_ac": "A0A8V0Z2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3/entry#A0A8V0Z2L2-1", "sequence": { "sequence": "MEVPWLLLASALLLPLCKYVALELKSAFEETGKTKEVIDTKYGFLDGKGAAVKYTQSDIRLIEVTENICKRLLDYNLHKERSGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEYEDVIEDWYRHHQTEDLSQFLCADRVLKGKDASCLAEKWTGKKGDLASAGEKPSKKKSGKKKKKEGKEQSEGARSLPEEESGVQEAAPLPHSPTDEL", "length": 234, "header": "tr|A0A8V0Z2L2-1|A0A8V0Z9Y3_CHICK Computationally mapped isoform of Protein canopy homolog 3 OS=Gallus gallus OX=9031 GN=CNPY3 PE=1 SV=1 CANONICAL=A0A8V0Z9Y3-1" }, "locus": { "chromosome": "3", "start_pos": 15729765, "end_pos": 15726149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046057.1", "url": "https://www.ensembl.org/id/ENSGALT00010046057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027451.1", "url": "https://www.ensembl.org/id/ENSGALP00010027451.1" } ] } }, { "isoform_ac": "A0A8V0Z9Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3/entry#A0A8V0Z9Y3-1", "sequence": { "sequence": "MEVPWLLLASALLLPPGGAADPLPTLAPPLTMMVSGQWRRLVVCVVSELPASSGHAVWISSGNGSALQSFAYGASQEEGGTVCAVSILPDSPMEQELLACHVGPNSSAPAHSSSPIAVAGTDTGPAREQGCSSRRVALWVNVTQGQEGGCGSPFPAVPHPAGSDEEAELCPSTPAVCKYVALELKSAFEETGKTKEVIDTKYGFLDGKGAAVKYTQSDIRLIEVTENICKRLLDYNLHKERSGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEYEDVIEDWYRHHQTEDLSQFLCADRVLKGKDASCLAEKWTGKKGDLASAGEKPSKKKSGKKKKKEGKEQSEGARSLPEEESGVQEAAPLPHSPTDEL", "length": 394, "header": "tr|A0A8V0Z9Y3-1|A0A8V0Z9Y3_CHICK Isoform 1 of Protein canopy homolog 3 OS=Gallus gallus OX=9031 GN=CNPY3 PE=1 SV=1 CANONICAL=A0A8V0Z9Y3-1" }, "locus": { "chromosome": "3", "start_pos": 15729765, "end_pos": 15726149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046055.1", "url": "https://www.ensembl.org/id/ENSGALT00010046055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027449.1", "url": "https://www.ensembl.org/id/ENSGALP00010027449.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858990", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y3" }, { "id": "PF11938", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11938" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF3456", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 322, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8C6-1", "uniprot_ac": "A0A8V0Z8C6", "uniprot_id": "A0A8V0Z8C6_CHICK", "mass": { "chemical_mass": 55058.0, "monoisotopic_mass": 55058.0 }, "refseq": {}, "gene_names": [ { "name": "SERPINA10", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6" } ] } ], "protein_names": [ { "name": "Serpin family A member 10", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPINA10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6", "locus": { "chromosome": "5", "start_pos": 45021096, "end_pos": 45038833, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017460", "url": "https://www.ensembl.org/id/ENSGALG00010017460" } ] } } ], "crossref": [ { "id": "A0A8V0Z8C6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8C6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2L9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKALILTHPFEAQNFRGEERKRKKKNSLLDTNMKIRIYLLLLCELCFEISKADIKPKSPKKDKRLNFLGRNKNVSISEEWHQHKNDHKPLEEQSFEELTLHNFTEKTANFGFNLYRKIAMKLDNNIIISPLSVTTLMATYLLAAEGETHRQIAKALNLHSLKDRDRHYLPALFKQLKDNITTNEELLFVQGILSFIQKDFTVREAFLNLSKQYFDMEFLCVDFQNSTQAKFVINQNIKQRTKGKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEIETFHINKYRSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKGKAYMLIVIPEKGEDYVSLEDHLTMELVESWLANMKSRNMDISFPKFKLEQKYKMKKLLYALGIKNLFARTADLSHLTDQKHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSVPPVLKVDRPFLFMIFEETFKTLLFIGRVVDPTET", "length": 471, "header": "tr|A0A8V0Z8C6-1|A0A8V0Z8C6_CHICK Isoform 1 of Serpin family A member 10 OS=Gallus gallus OX=9031 GN=SERPINA10 PE=1 SV=1 CANONICAL=A0A8V0Z8C6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6/entry#A0A8V0Z2L9-1", "sequence": { "sequence": "MKIRIYLLLLCELCFEISKADIKPKSPKKDKRLNFLGRNKNVSISEEWHQHKNDHKPLEEQSFEELTLHNFTEKTANFGFNLYRKIAMKLDNNIIISPLSVTTLMATYLLAAEGETHRQIAKALNLHSLKDRDRHYLPALFKQLKDNITTNEELLFVQDFQNSTQAKFVINQNIKQRTKGKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEIETFHINKYRSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKGKAYMLIVIPEKGEDYVSLEDHLTMELVESWLANMKSRNMDISFPKFKLEQKYKMKKLLYALGIKNLFARTADLSHLTDQKHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSVPPVLKVDRPFLFMIFEETFKTLLFIGRVVDPTET", "length": 408, "header": "tr|A0A8V0Z2L9-1|A0A8V0Z8C6_CHICK Computationally mapped isoform of Serpin family A member 10 OS=Gallus gallus OX=9031 GN=SERPINA10 PE=1 SV=1 CANONICAL=A0A8V0Z8C6-1" }, "locus": { "chromosome": "5", "start_pos": 45025823, "end_pos": 45021199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042163.1", "url": "https://www.ensembl.org/id/ENSGALT00010042163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024700.1", "url": "https://www.ensembl.org/id/ENSGALP00010024700.1" } ] } }, { "isoform_ac": "A0A8V0Z8C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C6/entry#A0A8V0Z8C6-1", "sequence": { "sequence": "MKALILTHPFEAQNFRGEERKRKKKNSLLDTNMKIRIYLLLLCELCFEISKADIKPKSPKKDKRLNFLGRNKNVSISEEWHQHKNDHKPLEEQSFEELTLHNFTEKTANFGFNLYRKIAMKLDNNIIISPLSVTTLMATYLLAAEGETHRQIAKALNLHSLKDRDRHYLPALFKQLKDNITTNEELLFVQGILSFIQKDFTVREAFLNLSKQYFDMEFLCVDFQNSTQAKFVINQNIKQRTKGKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEIETFHINKYRSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKGKAYMLIVIPEKGEDYVSLEDHLTMELVESWLANMKSRNMDISFPKFKLEQKYKMKKLLYALGIKNLFARTADLSHLTDQKHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSVPPVLKVDRPFLFMIFEETFKTLLFIGRVVDPTET", "length": 471, "header": "tr|A0A8V0Z8C6-1|A0A8V0Z8C6_CHICK Isoform 1 of Serpin family A member 10 OS=Gallus gallus OX=9031 GN=SERPINA10 PE=1 SV=1 CANONICAL=A0A8V0Z8C6-1" }, "locus": { "chromosome": "5", "start_pos": 45036355, "end_pos": 45021199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042166.1", "url": "https://www.ensembl.org/id/ENSGALT00010042166.1" }, { "database": "Ensembl 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152608.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152608" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATAD3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZA27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA27", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19512", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19512", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419412", "url": "https://www.ncbi.nlm.nih.gov/gene/419412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419412", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKSITGG", "url": "https://omabrowser.org/oma/group/HKSITGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2M3", "url": "https://www.orthodb.org/?gene=A0A8V0Z2M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA27", "url": "https://www.orthodb.org/?gene=A0A8V0ZA27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23075:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23075:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWLFGINRGSAPAGGGESGQGGAGLSLPPGPGGGGGPAGSGGAGDRSTPKDKWSNFDPTGLERAAKAARELDASRHAKDALSLAQMQEQTLQLEQQAKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVRETSRITVLEALKHPIKVGKRLTSKAQDALEGVVLSPQLEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAIHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNFDLPQLEERERLVRMYFDRHVLKPATEGKQRLKLAQFDYGKKCSEIARLTEGMSGREISQLAVAWQAAAYASEDGVLTEAMIDARVADAVQQHRQKMEWLKAEGAEASKEGVRTPLLPFPKGTPV", "length": 604, "header": "tr|A0A8V0ZA27-1|A0A8V0ZA27_CHICK Isoform 1 of ATPase family AAA domain containing 3B OS=Gallus gallus OX=9031 GN=ATAD3B PE=1 SV=1 CANONICAL=A0A8V0ZA27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27/entry#A0A8V0Z2M3-1", "sequence": { "sequence": "MLGNLFSQKEQRCIGHAKDALSLAQMQEQTLQLEQQAKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVRETSRITVLEALKHPIKVGKRLTSKAQDALEGVVLSPQLEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAIHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNFDLPQLEERERLVRMYFDRHVLKPATEGKQRLKLAQFDYGKKCSEIARLTEGMSGREISQLAVAWQAAAYASEDGVLTEAMIDARVADAVQQHRQKMEWLKAEGAEASKEGVRTPLLPFPKGTPV", "length": 543, "header": "tr|A0A8V0Z2M3-1|A0A8V0ZA27_CHICK Computationally mapped isoform of ATPase family AAA domain containing 3B OS=Gallus gallus OX=9031 GN=ATAD3B PE=1 SV=1 CANONICAL=A0A8V0ZA27-1" }, "locus": { "chromosome": "21", "start_pos": 2168073, "end_pos": 2150349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042838.1", "url": "https://www.ensembl.org/id/ENSGALT00010042838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025328.1", "url": "https://www.ensembl.org/id/ENSGALP00010025328.1" } ] } }, { "isoform_ac": "A0A8V0ZA27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27/entry#A0A8V0ZA27-1", "sequence": { "sequence": "MSWLFGINRGSAPAGGGESGQGGAGLSLPPGPGGGGGPAGSGGAGDRSTPKDKWSNFDPTGLERAAKAARELDASRHAKDALSLAQMQEQTLQLEQQAKLKEYEAAIEQLKNEQIRVQAEERRKTLSEETKQHQARAQYQDKLARQRYDEQMRQQQLANEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESLKTAGMLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVRETSRITVLEALKHPIKVGKRLTSKAQDALEGVVLSPQLEARVRDIAIATRNTKKNKSLYRNILMYGPPGTGKTLFAKKLAVHSGMDYAIMTGGDVAPMGREGVTAIHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVNFDLPQLEERERLVRMYFDRHVLKPATEGKQRLKLAQFDYGKKCSEIARLTEGMSGREISQLAVAWQAAAYASEDGVLTEAMIDARVADAVQQHRQKMEWLKAEGAEASKEGVRTPLLPFPKGTPV", "length": 604, "header": "tr|A0A8V0ZA27-1|A0A8V0ZA27_CHICK Isoform 1 of ATPase family AAA domain containing 3B OS=Gallus gallus OX=9031 GN=ATAD3B PE=1 SV=1 CANONICAL=A0A8V0ZA27-1" }, "locus": { "chromosome": "21", "start_pos": 2167517, "end_pos": 2150349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042832.1", "url": "https://www.ensembl.org/id/ENSGALT00010042832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025322.1", "url": "https://www.ensembl.org/id/ENSGALP00010025322.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419412", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A7YWC4-1", "protein_name": "ATPase family AAA domain-containing protein 3", "gene_name": "ATAD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSWLFGIKGSKGEGTGPPLPLPPVQPGGEGSGDGGAGDRPGPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEHQAKLKEYEAAVEQLKGDQIRVQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEALRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGIYSAKNATSVAGRYIEARLGKPSLVRETSRITVLEALRHPIQVSRRLLSKPQDALEGVVLSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGRDGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVSFELPQREERERLVRMYFDKYVLKPATEGKQRLKLAQFDYGKKCSEIAQLTEGMSGREISQLAVAWQAMAYASEDGVLTEAMMDARVQDAIQQHRQKMQWLKAEGSQPPTLRTQAE", "length": 586 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJE4-1", "protein_name": "ATPase family AAA domain containing 3A", "gene_name": "ATAD3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQEQTLQLEQQAKLKEYEAAVEQLKSEQIRVQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEALRRATVEREMELRHKNEMLRVEAEARARAKAERENADITREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLALGVYSAKNATSVAGRYVEARLGKPSLVRETSRITALEALRHPVQVGRRLLSKPQDALEGVVLSPSLEARVRDLAIATRNTRKNRSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGRDGVTAVHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRAALNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEIVSFDLPRREERERLVRMYFDKHVLKPATEGKQRLKLAQFDYGKKCSEIAELTEGMSGREISQLAVAWQAMAYASEDGVLTEAMMDARVQDAIQQHRQKMQWLKAEGSQPPVSAWTK", "length": 507 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I432-1", "protein_name": "ATPase family AAA domain-containing protein 3A", "gene_name": "LOC100772005", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSWLFGINKGPKGEGTGPPLPLPPAQPGAEGGGDRGAGDRQSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATAVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYASENGVLTEAMMDARVEDAVQQHQQKMQWLKVERPNPEASEPPCP", "length": 587 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3KRE0-1", "protein_name": "ATPase family AAA domain-containing protein 3A", "gene_name": "Atad3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLFGIKGPKGEGTGPPLPLPPAQPGAESGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLNEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTAGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSEASKPPHPSLLSC", "length": 591 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q925I1-1", "protein_name": "ATPase family AAA domain-containing protein 3A", "gene_name": "Atad3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWLFGIKGPKGEGTGPPLPLPPAQPGAEGGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLTEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLLGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSQTNKPPHPSLLSC", "length": 591 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVI7-2", "protein_name": "ATPase family AAA domain-containing protein 3A", "gene_name": "ATAD3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWLFGINKGPKGEGAGPPPPLPPAQPGAEGGGDRGLGDRPAPKDKWSNFDPTGLERAAKAARELEHSRYAKDALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRAQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTVLESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATLVAGRFIEARLGKPSLVRETSRITVLEALRHPIQVSRRLLSRPQDALEGVVLSPSLEARVRDIAIATRNTKKNRSLYRNILMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLVLASNQPEQFDWAINDRINEMVHFDLPGQEERERLVRMYFDKYVLKPATEGKQRLKLAQFDYGRKCSEVARLTEGMSGREIAQLAVSWQATAYASEDGVLTEAMMDTRVQDAVQQHQQKMCWLKAEGPGRGDEPSPS", "length": 586 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEX6-1", "protein_name": "ATPase family AAA domain-containing protein 3A homolog", "gene_name": "bor", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSWLLGRNRQQPQPDQTAGFSEGGGAADPEGRTAGEKSGDSQLSRAERKAMEAYRFDSSALERAADAAKTLERSKHAREALELSKMQEATRQTEYNTKVKEYEAHIEQAKVEQKRIDHEERRKTLIEETKQQQQRAQYQDQLSRKRYEDQLLQQQRVQEENLRKQEESVQRQEAMRRQTIEHEIEMKEKNRLKLLEHELRAKARVDRENRDINLEKIRLKAQEHRTTVLEGIKTAGTVIGAGAEAMLTDWDKVLTAAGGLSLLALGVYTAKGATGVVSRYVEARIGKPTLVGETSRFAFLDALKNPLHYLKRLRAKPTDALQGVVLNPKLEERLRDIAIATKNTRINKGMYRNVLMHGPPGTGKTMFAKKLAEHSGMDFAIMTGGDVAPMGKEGVTAIHKVFDWSHTSRRGLLLFVDEADAFLRKRSSEKISEDLRAALNAFLYRTSEQNPKFMLVLASNTPEQFDYAINDRLDEMVEFTLPGLEERERLLRLYFDKYVLQPAAAGAKRFKLDTFDYGKTCSKMAALCEGMSGREISKLGVSWQAAVYASEDGLLTEKMVLDRCYSAAQQHKQKMAWLSDQERADHKSITGTAAPPLTLTAKKL", "length": 604 }, "evidence": [ { "id": "A0A8V0ZA27", "url": "https://omabrowser.org/oma/group/A0A8V0ZA27/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "negative regulation of PERK-mediated unfolded protein response", "id": "GO:1903898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZA27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA27" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 506, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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266114.0, "monoisotopic_mass": 266114.0 }, "refseq": { "ac": "XP_040544652", "name": "golgin subfamily A member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040544652" }, "gene_names": [ { "name": "GOLGA4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4" } ] }, { "name": "GOLGA4", "type": "synonym", "evidence": [ { "id": "XP_040544652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040544652" } ] } ], "protein_names": [ { "name": "Golgin A4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4/entry#names_and_taxonomy" } ] }, { "name": "golgin subfamily A member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040544652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040544652" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040544652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040544652" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4", "locus": { "chromosome": "2", "start_pos": 48866760, "end_pos": 48945917, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017662", "url": "https://www.ensembl.org/id/ENSGALG00010017662" } ] } } ], "crossref": [ { "id": "420758", "url": "https://www.ncbi.nlm.nih.gov/gene/420758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEFRNQG", "url": "https://omabrowser.org/oma/group/DEFRNQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2N2", "url": "https://www.orthodb.org/?gene=A0A8V0Z2N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3X1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9P4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Q4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19327:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19327:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040544652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040544652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3X1", "url": 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"length": 2285, "header": "tr|A0A8V0Z9P4-1|A0A8V0Z9P4_CHICK Isoform 1 of Golgin A4 OS=Gallus gallus OX=9031 GN=GOLGA4 PE=1 SV=1 CANONICAL=A0A8V0Z9P4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4/entry#A0A8V0Z2N2-1", "sequence": { "sequence": "MFKKLKQKISEEQAPPRGAGGRAAPLQPQNLPKQSIPRSTENNGSEPASPQPSDAQSFTQRLQLRVPSMESLFRSPVKESLFRSSSKESLVRTSSRDSLNRLDVDAAGPTFDPPSDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDLELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKKMYVTSVGTPYRDGNLHHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPADQTQKILEREDARPLFASPRSGIF", "length": 2220, "header": "tr|A0A8V0Z2N2-1|A0A8V0Z9P4_CHICK Computationally mapped isoform of Golgin A4 OS=Gallus gallus OX=9031 GN=GOLGA4 PE=1 SV=1 CANONICAL=A0A8V0Z9P4-1" }, "locus": { "chromosome": "2", "start_pos": 48927885, "end_pos": 48869586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042689.1", "url": "https://www.ensembl.org/id/ENSGALT00010042689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025179.1", "url": "https://www.ensembl.org/id/ENSGALP00010025179.1" } ] } }, { "isoform_ac": "A0A8V0Z3X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4/entry#A0A8V0Z3X1-1", "sequence": { "sequence": "MFKKLKQKISEEQAPPRGAGGRAAPLQPQVPPKSPPLSDKRSRSSSLAEQNDEGTLTPDKENLPKQSIPRSTENNGSEPASPQPSDAQSFTQRLQLRVPSMESLFRSPVKESLFRSSSKESLVRTSSRDSLNRLDVDAAGPTFDPPSDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDLELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKKMYVTSVGTPYRDGNLHHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPADQTQKILEREDARPLSWL", "length": 2246, "header": "tr|A0A8V0Z3X1-1|A0A8V0Z3X1_CHICK Computationally mapped isoform of Golgin A4 OS=Gallus gallus OX=9031 GN=GOLGA4 PE=1 SV=1 CANONICAL=A0A8V0Z9P4-1" }, "locus": { "chromosome": "2", "start_pos": 48927885, "end_pos": 48867540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042703.1", "url": "https://www.ensembl.org/id/ENSGALT00010042703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025193.1", "url": "https://www.ensembl.org/id/ENSGALP00010025193.1" } ] } }, { "isoform_ac": "A0A8V0Z9P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4/entry#A0A8V0Z9P4-1", "sequence": { "sequence": "MFKKLKQKISEEQAPPRGAGGRAAPLQPQVPPKSPPLSDKRSRSSSLAEQNDEGTLTPDKELLAGMIAEPAFLSEYTIFALDPTKQPKPQSDGVNLPKQSIPRSTENNGSEPASPQPSDAQSFTQRLQLRVPSMESLFRSPVKESLFRSSSKESLVRTSSRDSLNRLDVDAAGPTFDPPSDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDLELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKKMYVTSVGTPYRDGNLHHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPADQTQKILEREDARPLFASPRSGIF", "length": 2285, "header": "tr|A0A8V0Z9P4-1|A0A8V0Z9P4_CHICK Isoform 1 of Golgin A4 OS=Gallus gallus OX=9031 GN=GOLGA4 PE=1 SV=1 CANONICAL=A0A8V0Z9P4-1" }, "locus": { "chromosome": "2", "start_pos": 48927885, "end_pos": 48869586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042696.1", "url": "https://www.ensembl.org/id/ENSGALT00010042696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025186.1", "url": "https://www.ensembl.org/id/ENSGALP00010025186.1" } ] } }, { "isoform_ac": "A0A8V0Z9Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P4/entry#A0A8V0Z9Q4-1", "sequence": { "sequence": "MFKKLKQKISEEQAPPRGAGGRAAPLQPQVPPKSPPLSDKRSRSSSLAEQNDEGTLTPDKELLAGMIAEPAFLSEYTIFALDPTKQPKPQSDGVNLPKQSIPRSTENNGSEPASPQPSDAQSFTQRLQLRVPSMESLFRSPVKESLFRSSSKESLVRTSSRDSLNRLDVDAAGPTFDPPSDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDLELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKKMYVTSVGTPYRDGNLHHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPADQTQKILEREDARPLSWL", "length": 2279, "header": "tr|A0A8V0Z9Q4-1|A0A8V0Z9Q4_CHICK Computationally mapped isoform of Golgin A4 OS=Gallus gallus OX=9031 GN=GOLGA4 PE=1 SV=1 CANONICAL=A0A8V0Z9P4-1" }, "locus": { "chromosome": "2", "start_pos": 48927885, "end_pos": 48867540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042706.1", "url": "https://www.ensembl.org/id/ENSGALT00010042706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025196.1", "url": "https://www.ensembl.org/id/ENSGALP00010025196.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "Q13439-1", "protein_name": "Golgin subfamily A member 4", "gene_name": "GOLGA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRESGDTQSFAQKLQLRVPSVESLFRSPIKESLFRSSSKESLVRTSSRESLNRLDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAKVITTVLKFPDDQTQKILEREDARLMFTSPRSGIF", "length": 2230 }, "evidence": [ { "id": "A0A8V0Z9P4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91VW5-1", "protein_name": "Golgin subfamily A member 4", "gene_name": "Golga4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.orthodb.org/?gene=A0A8V0Z2N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2P2", "url": "https://www.orthodb.org/?gene=A0A8V0Z2P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8I4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA13", "url": "https://www.orthodb.org/?gene=A0A8V0ZA13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFY7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P3A5", "url": "https://www.orthodb.org/?gene=F1P3A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24169:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24169:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00554", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00554", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1169091", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3A5", "url": "https://www.uniprot.org/uniprotkb/F1P3A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P3A5-1", "url": "https://www.uniprot.org/uniprotkb/F1P3A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSNIDKGSYIGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 607, "header": "tr|A0A8V0Z8I4-1|A0A8V0Z8I4_CHICK Isoform 1 of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#A0A8V0Z2N4-1", "sequence": { "sequence": "MELRSLKCISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 603, "header": "tr|A0A8V0Z2N4-1|A0A8V0Z8I4_CHICK Computationally mapped isoform of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2115403, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046097.1", "url": "https://www.ensembl.org/id/ENSGALT00010046097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027477.1", "url": "https://www.ensembl.org/id/ENSGALP00010027477.1" } ] } }, { "isoform_ac": "A0A8V0Z2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#A0A8V0Z2P2-1", "sequence": { "sequence": "MAGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNNDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 563, "header": "tr|A0A8V0Z2P2-1|A0A8V0Z8I4_CHICK Computationally mapped isoform of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2114962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046114.1", "url": "https://www.ensembl.org/id/ENSGALT00010046114.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027488.1", "url": "https://www.ensembl.org/id/ENSGALP00010027488.1" } ] } }, { "isoform_ac": "A0A8V0Z8I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#A0A8V0Z8I4-1", "sequence": { "sequence": "MQSNIDKGSYIGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 607, "header": "tr|A0A8V0Z8I4-1|A0A8V0Z8I4_CHICK Isoform 1 of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2115573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046091.1", "url": "https://www.ensembl.org/id/ENSGALT00010046091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027474.1", "url": "https://www.ensembl.org/id/ENSGALP00010027474.1" } ] } }, { "isoform_ac": "A0A8V0ZA13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#A0A8V0ZA13-1", "sequence": { "sequence": "MRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 579, "header": "tr|A0A8V0ZA13-1|A0A8V0ZA13_CHICK Computationally mapped isoform of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2119866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046102.1", "url": "https://www.ensembl.org/id/ENSGALT00010046102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027480.1", "url": "https://www.ensembl.org/id/ENSGALP00010027480.1" } ] } }, { "isoform_ac": "A0A8V0ZFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#A0A8V0ZFY7-1", "sequence": { "sequence": "MPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 593, "header": "tr|A0A8V0ZFY7-1|A0A8V0ZFY7_CHICK Computationally mapped isoform of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=1 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2119585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046088.1", "url": "https://www.ensembl.org/id/ENSGALT00010046088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027473.1", "url": "https://www.ensembl.org/id/ENSGALP00010027473.1" } ] } }, { "isoform_ac": "F1P3A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4/entry#F1P3A5-1", "sequence": { "sequence": "MAGISEPYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFGKVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGIQCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLPDEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFLLCDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPITVKMQLRRPSDQEVSEPMDFRYLPDEKDPYGNKAKRQRSTLAWQKLIQDCGSAVTERPKAAPIPTVNPEGKLIKKEPNMFSPTLMLPGLGTLTSSSQMYPPCSQMPHQPAQLGPGKQDTLPSCWQQLFSSSPSASSLLSMHPHNSFTAEVPQPSAQGSSSLPAFHDNPLNWPDEKDSSFYRNFGSTNGMGAAMVSAADMQSASSNSIVHATHQASATAASIVNMETNDMNCTSLNFEKYTQVLNVSNHRQQLHQAPAACPPVAAPGSTPFSSQPNLADTAVYNSFLDQEVISDSRLSTNPLQNHQNSLTLTDNQFYDTDGVHTDELYQSFQLDTNILQSYNH", "length": 598, "header": "tr|F1P3A5-1|A0A8V0Z8I4_CHICK Computationally mapped isoform of REL proto-onco, NF-kB subunit OS=Gallus gallus OX=9031 GN=REL PE=4 SV=3 CANONICAL=A0A8V0Z8I4-1" }, "locus": { "chromosome": "3", "start_pos": 2147082, "end_pos": 2114962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046110.1", "url": "https://www.ensembl.org/id/ENSGALT00010046110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027485.1", "url": "https://www.ensembl.org/id/ENSGALP00010027485.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396500", "resource": "KEGG Pathway" }, { "id": "R-GGA-1169091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "resource": "Reactome", "description": "Activation of NF-kappaB in B cells" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "non-canonical NF-kappaB signal transduction", "id": "GO:0038061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038061", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" }, { "name": "negative regulation of interferon-beta production", "id": "GO:0032688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I4" }, { "id": "PS50254", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50254" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RHD", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 190, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { 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"species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ESPN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995", "locus": { "chromosome": "21", "start_pos": 594516, "end_pos": 606912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019076", "url": "https://www.ensembl.org/id/ENSGALG00010019076" } ] } } ], "crossref": [ { "id": "A0A8V0Z995", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z995", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2S5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z995", "url": "https://www.orthodb.org/?gene=A0A8V0Z995", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG29", "url": "https://www.orthodb.org/?gene=A0A8V0ZG29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24153:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z2S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z995-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPLHPSISAPSSTRSPLLEVQDSPGCQCPLPFLPQDTDNSGATILHLAARFGHHEVIEWLLRFGGSDPTAATDTGALPVHYAAAKGDFPSLRLLLGHCPSTLSAQTKTGATPLYLACQEGHLEIIQYLVKDCGADPHVRANDGMTPLHAAAQMGHNTVIVWLMSFTTVSLSERDDDGATAMHFAASRGHAKVLSWLLLHGGEITADGWGGTPLHDAAENGELECCQILVVNGADLSIRDQDGYTAADLADYNGHIHCAKYLRTVENMSVEHRVLSRDPSADGECRQPDSGMSSPNTTASAPQARFEVGSPASTLSNYDSCNSSQSSTGEKRGGPHAAPAARVPEPALTDMQAYMDMLNPETRPRGRGLASEGPPPPPPSFPPPPPPPATRPPPPPPGYPAPAPPTAPDTADIYVQAKNNLRHVESQVLRRELVSREGSPEGLRRADSTRRSRNFSKQPSTGDYYKHLGPSAAELPGPRRMAHSEESSPLPADTMHNGGPAESKPGTELPPPPPPPPLPDAACPPPPPPPPPAGPRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGFTTVFSGSGQAGANADSPASSPSPTRTPTPPATPEAGGPPRCMAGGSPEPVLNGSSPVPGPGAMAPPDVEALVPSHDEQGRPIPEWKRQVMVRKLQLRMQEEEEQRRKEKEEEARLASMPAWRRDILRKKLEEEREQKRKEQEKQKREEEEKEKEQSEKLRTLGYDETKLAPWQRQIILKKGDIAKH", "length": 765, "header": "tr|A0A8V0Z995-1|A0A8V0Z995_CHICK Isoform 1 of Espin OS=Gallus gallus OX=9031 GN=ESPN PE=1 SV=1 CANONICAL=A0A8V0Z995-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995/entry#A0A8V0Z2S5-1", "sequence": { "sequence": "PAHDAAATGNLACLQWLLTQGGCGVQDTDNSGATILHLAARFGHHEVIEWLLRFGGSDPTAATDTGALPVHYAAAKGDFPSLRLLLGHCPSTLSAQTKTGATPLYLACQEGHLEIIQYLVKDCGADPHVRANDGMTPLHAAAQMGHNTVIVWLMSFTTVSLSERDDDGATAMHFAASRGHAKVLSWLLLHGGEITADGWGGTPLHDAAENGELECCQILVVNGADLSIRDQDGYTAADLADYNGHIHCAKYLRTVENMSVEHRVLSRDPSADGECRQPDSGMSSPNTTASAPQARFEVGSPASTLSNYDSCNSSQSSTGEKRGGPHAAPAARVPEPALTDMQAYMDMLNPETRPRGRGLASEGPPPPPPSFPPPPPPPATRPPPPPPGYPAPAPPTAPDTADIYVQAKNNLRHVESQVLRRELVSREGSPEGLRRADSTRRSRNFSKQPSTGDYYKHLGPSAAELPGPRRMAHSEESSPLPADTMHNGGPAESKPGTELPPPPPPPPLPDAACPPPPPPPPPAGPRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGFTTVFSGSGQAGANADSPASSPSPTRTPTPPATPEAGGPPRCMAGGSPEPVLNGSSPVPGPGAMAPPDVEALVPSHDEQGRPIPEWKRQVMVRKLQLRMQEEEEQRRKEKEEEARLASMPAWRRDILRKKLEEEREQKRKEQEKQKREEEEKEKEQSEKLRTLGYDETKLAPWQRQIILKKGDIAKH", "length": 755, "header": "tr|A0A8V0Z2S5-1|A0A8V0Z995_CHICK Computationally mapped isoform of Espin OS=Gallus gallus OX=9031 GN=ESPN PE=1 SV=1 CANONICAL=A0A8V0Z995-1" }, "locus": { "chromosome": "21", "start_pos": 606882, "end_pos": 595520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046187.1", "url": "https://www.ensembl.org/id/ENSGALT00010046187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027523.1", "url": "https://www.ensembl.org/id/ENSGALP00010027523.1" } ] } }, { "isoform_ac": "A0A8V0Z995-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995/entry#A0A8V0Z995-1", "sequence": { "sequence": "MKPLHPSISAPSSTRSPLLEVQDSPGCQCPLPFLPQDTDNSGATILHLAARFGHHEVIEWLLRFGGSDPTAATDTGALPVHYAAAKGDFPSLRLLLGHCPSTLSAQTKTGATPLYLACQEGHLEIIQYLVKDCGADPHVRANDGMTPLHAAAQMGHNTVIVWLMSFTTVSLSERDDDGATAMHFAASRGHAKVLSWLLLHGGEITADGWGGTPLHDAAENGELECCQILVVNGADLSIRDQDGYTAADLADYNGHIHCAKYLRTVENMSVEHRVLSRDPSADGECRQPDSGMSSPNTTASAPQARFEVGSPASTLSNYDSCNSSQSSTGEKRGGPHAAPAARVPEPALTDMQAYMDMLNPETRPRGRGLASEGPPPPPPSFPPPPPPPATRPPPPPPGYPAPAPPTAPDTADIYVQAKNNLRHVESQVLRRELVSREGSPEGLRRADSTRRSRNFSKQPSTGDYYKHLGPSAAELPGPRRMAHSEESSPLPADTMHNGGPAESKPGTELPPPPPPPPLPDAACPPPPPPPPPAGPRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGFTTVFSGSGQAGANADSPASSPSPTRTPTPPATPEAGGPPRCMAGGSPEPVLNGSSPVPGPGAMAPPDVEALVPSHDEQGRPIPEWKRQVMVRKLQLRMQEEEEQRRKEKEEEARLASMPAWRRDILRKKLEEEREQKRKEQEKQKREEEEKEKEQSEKLRTLGYDETKLAPWQRQIILKKGDIAKH", "length": 765, "header": "tr|A0A8V0Z995-1|A0A8V0Z995_CHICK Isoform 1 of Espin OS=Gallus gallus OX=9031 GN=ESPN PE=1 SV=1 CANONICAL=A0A8V0Z995-1" }, "locus": { "chromosome": "21", "start_pos": 605776, "end_pos": 595520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046185.1", "url": "https://www.ensembl.org/id/ENSGALT00010046185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027522.1", "url": "https://www.ensembl.org/id/ENSGALP00010027522.1" } ] } }, { "isoform_ac": "A0A8V0ZG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995/entry#A0A8V0ZG29-1", "sequence": { "sequence": "MASGGRQCPSIAVAAGGSDALAVPARRSTLCGWHVPSPRGASGATDAASLGELGVGGCAEAWGAGSSCNLSARLRCHPRRRCRVALLVLPGAERAQRDAQSSPLPADTMHNGGPAESKPGTELPPPPPPPPLPDAACPPPPPPPPPAGPRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGFTTVFSGSGQAGANADSPASSPSPTRTPTPPATPEAGGPPRCMAGGSPEPVLNGSSPVPGPGAMAPPDVEALVPSHDEQGRPIPEWKRQVMVRKLQLRMQEEEEQRRKEKEEEARLASMPAWRRDILRKKLEEEREQKRKEQEKQKREEEEKEKEQSEKLRTLGYDETKLAPWQRQIILKKGDIAKH", "length": 379, "header": "tr|A0A8V0ZG29-1|A0A8V0ZG29_CHICK Computationally mapped isoform of Espin OS=Gallus gallus OX=9031 GN=ESPN PE=4 SV=1 CANONICAL=A0A8V0Z995-1" }, "locus": { "chromosome": "21", "start_pos": 601785, "end_pos": 595520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046180.1", "url": "https://www.ensembl.org/id/ENSGALT00010046180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027519.1", "url": "https://www.ensembl.org/id/ENSGALP00010027519.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 406, "start_aa": "Thr", "end_pos": 406, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr406", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 611, "start_aa": "Thr", "end_pos": 611, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr611", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" }, { "name": "microvillar actin bundle assembly", "id": "GO:0030034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z995", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z995" }, { "id": "PS51082", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH2", "eco_id": "ECO_0000259", "start_pos": 556, "end_pos": 573, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 406, 611 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V0Z930_CHICK", "mass": { "chemical_mass": 68207.0, "monoisotopic_mass": 68207.0 }, "refseq": {}, "gene_names": [ { "name": "CAMK2B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ], "protein_names": [ { "name": "Calcium/calmodulin dependent protein kinase II beta", "type": "synonym", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAMK2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930", "locus": { "chromosome": "22", "start_pos": 4538266, "end_pos": 4520277, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018835", "url": "https://www.ensembl.org/id/ENSGALG00010018835" } ] } } ], "crossref": [ { "id": "A0A8V0Z930", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z930", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374174", "url": "https://www.ncbi.nlm.nih.gov/gene/374174", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MEFHRFY", "url": "https://omabrowser.org/oma/group/MEFHRFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1Q7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1R7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7J8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z867", "url": "https://www.orthodb.org/?gene=A0A8V0Z867", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z872", "url": "https://www.orthodb.org/?gene=A0A8V0Z872", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z930", "url": "https://www.orthodb.org/?gene=A0A8V0Z930", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF14", "url": "https://www.orthodb.org/?gene=A0A8V0ZF14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF19", "url": "https://www.orthodb.org/?gene=A0A8V0ZF19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z1Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z867", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z867", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z867-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z867-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z872", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z872", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z872-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z872-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z930-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKVGGGPIAPCPLPTPPCPLPTPPCPCPLPTVAVSPSRSDRSPVPSQPFPRRAVAVSPPLPTSFSPTPLLVVLSHLPHSHPGISQPHHSHIPALCRAPYPPLPPLATSHGFTVSHSPLLGRPGARLYPRPHPTHVPHCHHSRVLVPPVCAITVCATVSPGFVTVLPTSPCPVLGCPHTFPAISHCRPPRPGATRCRADLVPLQGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALVGAPPRTYPHPTPPPLPSLHPIASIAMLASGTVGHGVGKRGTPPPAVSVPPSSKCPQSITGLTAPPTPPGTVGAGCGHRGSSGAGGCGGDTGTRAGAADEGQDVGGGGGGRGHGRELAAGPPWGGGRRTHPDLTAGAKGCWAARWGLRGGGGTSGRGHEGCPHGVDGKVGMQRRRGALCGSEQWVQSPPPPPGQSSGLRMWAQCPLHGGCKTWFPPPPPFSPLSPLSLN", "length": 654, "header": "tr|A0A8V0Z930-1|A0A8V0Z930_CHICK Isoform 1 of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z1Q7-1", "sequence": { "sequence": "MATTVPCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSGEPPPSRPRDASPPPASPARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 467, "header": "tr|A0A8V0Z1Q7-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4520361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045531.1", "url": "https://www.ensembl.org/id/ENSGALT00010045531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027158.1", "url": "https://www.ensembl.org/id/ENSGALP00010027158.1" } ] } }, { "isoform_ac": "A0A8V0Z1R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z1R7-1", "sequence": { "sequence": "MATTVPCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPPSMSAAAAPLGLVEQAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALEPQTTVIHNPADGIKESSDSTNTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 541, "header": "tr|A0A8V0Z1R7-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4520361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045551.1", "url": "https://www.ensembl.org/id/ENSGALT00010045551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027168.1", "url": "https://www.ensembl.org/id/ENSGALP00010027168.1" } ] } }, { "isoform_ac": "A0A8V0Z7J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z7J8-1", "sequence": { "sequence": "MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPPSMSAAAAPLGLVEQAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALPASRRSLRSQSSSSRPSTTGTSRPTRRSATRGSPPSSPKRWATWWRAWTSTASTSRTCCPRTTNRSTRPS", "length": 317, "header": "tr|A0A8V0Z7J8-1|A0A8V0Z7J8_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536705, "end_pos": 4528294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045499.1", "url": "https://www.ensembl.org/id/ENSGALT00010045499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027145.1", "url": "https://www.ensembl.org/id/ENSGALP00010027145.1" } ] } }, { "isoform_ac": "A0A8V0Z867-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z867-1", "sequence": { "sequence": "MATTVPCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALEPQTTVIHNPADGIKESSDSTNTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 518, "header": "tr|A0A8V0Z867-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4520361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045540.1", "url": "https://www.ensembl.org/id/ENSGALT00010045540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027162.1", "url": "https://www.ensembl.org/id/ENSGALP00010027162.1" } ] } }, { "isoform_ac": "A0A8V0Z872-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z872-1", "sequence": { "sequence": "MATTVPCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPPSMSAAAAPLGLVEQAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALESSDSTNTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 526, "header": "tr|A0A8V0Z872-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4520361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045547.1", "url": "https://www.ensembl.org/id/ENSGALT00010045547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027167.1", "url": "https://www.ensembl.org/id/ENSGALP00010027167.1" } ] } }, { "isoform_ac": "A0A8V0Z930-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0Z930-1", "sequence": { "sequence": "MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKVGGGPIAPCPLPTPPCPLPTPPCPCPLPTVAVSPSRSDRSPVPSQPFPRRAVAVSPPLPTSFSPTPLLVVLSHLPHSHPGISQPHHSHIPALCRAPYPPLPPLATSHGFTVSHSPLLGRPGARLYPRPHPTHVPHCHHSRVLVPPVCAITVCATVSPGFVTVLPTSPCPVLGCPHTFPAISHCRPPRPGATRCRADLVPLQGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALVGAPPRTYPHPTPPPLPSLHPIASIAMLASGTVGHGVGKRGTPPPAVSVPPSSKCPQSITGLTAPPTPPGTVGAGCGHRGSSGAGGCGGDTGTRAGAADEGQDVGGGGGGRGHGRELAAGPPWGGGRRTHPDLTAGAKGCWAARWGLRGGGGTSGRGHEGCPHGVDGKVGMQRRRGALCGSEQWVQSPPPPPGQSSGLRMWAQCPLHGGCKTWFPPPPPFSPLSPLSLN", "length": 654, "header": "tr|A0A8V0Z930-1|A0A8V0Z930_CHICK Isoform 1 of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4533737, "end_pos": 4528294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045483.1", "url": "https://www.ensembl.org/id/ENSGALT00010045483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027136.1", "url": "https://www.ensembl.org/id/ENSGALP00010027136.1" } ] } }, { "isoform_ac": "A0A8V0ZF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0ZF14-1", "sequence": { "sequence": "RTSLTCWGHLGCSPPHPPPSKCWGSPSAESRPRVLSHGEGVRGIGGPCLGVGGGDTECLPVVPRGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKVGGGPIESSDSTNTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 499, "header": "tr|A0A8V0ZF14-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4521440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045524.1", "url": "https://www.ensembl.org/id/ENSGALT00010045524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027154.1", "url": "https://www.ensembl.org/id/ENSGALP00010027154.1" } ] } }, { "isoform_ac": "A0A8V0ZF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930/entry#A0A8V0ZF19-1", "sequence": { "sequence": "MATTVPCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKVGGVGRQTTAPPSMSAAAAPLGLVEQAKSLLNKKADGVKPQTNSTKGSAGVTSPKGTLPPAALVGESSDSTNTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNNKPIHTTILNPHVHVIGEDAACIAYIRLTQYLDAQGRPRTSQSEETRVWHRRDGKWQNVHFHGSGAPVAPLQ", "length": 516, "header": "tr|A0A8V0ZF19-1|A0A8V0Z930_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II beta OS=Gallus gallus OX=9031 GN=CAMK2B PE=4 SV=1 CANONICAL=A0A8V0Z930-1" }, "locus": { "chromosome": "22", "start_pos": 4536896, "end_pos": 4520361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045534.1", "url": "https://www.ensembl.org/id/ENSGALT00010045534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027159.1", "url": "https://www.ensembl.org/id/ENSGALP00010027159.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 437, "start_aa": "Thr", "end_pos": 437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr437", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AGQ9-1", "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMK2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSTHTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSKETRVWHRRDGKWQNVHFHCSGAPVAPLQ", "length": 542 }, "evidence": [ { "id": "A0A8V0Z930", "url": "https://omabrowser.org/oma/group/A0A8V0Z930/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08413-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "Camk2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRPDGKWQNVHFHCSGAPVAPLQ", "length": 542 }, "evidence": [ { "id": "A0A8V0Z930", "url": "https://omabrowser.org/oma/group/A0A8V0Z930/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28652-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "Camk2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ", "length": 542 }, "evidence": [ { "id": "A0A8V0Z930", "url": "https://omabrowser.org/oma/group/A0A8V0Z930/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13554-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVRRGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPPPCLSPALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ", "length": 666 }, "evidence": [ { "id": "A0A8V0Z930", "url": "https://omabrowser.org/oma/group/A0A8V0Z930/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3MHJ9-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIMAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGATMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSTHTTIEDEDTKARKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ", "length": 542 }, "evidence": [ { "id": "A0A8V0Z930", "url": "https://omabrowser.org/oma/group/A0A8V0Z930/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z930", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", 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"id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": 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"A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": 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"id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": 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"id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q9I9E0", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] } ] }, { "uniprot_ac": "Q9IA88", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 143, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.17", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.17", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17" }, { "id": "2.7.11.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.17" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48, 185, 192, 201, 437, 492 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8Y1-1", "uniprot_ac": "A0A8V0Z8Y1", "uniprot_id": "A0A8V0Z8Y1_CHICK", "mass": { "chemical_mass": 73594.0, "monoisotopic_mass": 73594.0 }, "refseq": {}, "gene_names": [ { "name": "RNF207", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ] } ], "protein_names": [ { "name": "Ring finger protein 207", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF207", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1", "locus": { "chromosome": "21", "start_pos": 625197, "end_pos": 631560, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019206", "url": "https://www.ensembl.org/id/ENSGALG00010019206" } ] } } ], "crossref": [ { "id": "A0A8V0Z8Y1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8Y1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19814", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19814", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419374", "url": "https://www.ncbi.nlm.nih.gov/gene/419374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ELDTMYF", "url": "https://omabrowser.org/oma/group/ELDTMYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22635", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22635", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22635:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22635:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRCRAPEERTEQREEQRGLTQQPPPGSPSTHKVGGVHDAILHRVRAVQRELQHLLLFFATLRCGFLLRDGEREERHPSVVRGGTGLPPVDRLLQFLVDSSAEGSEDAQCANCDRLCAEADLDTMCFCNTCSQPLCAPCREETHRAKVFARHEIVSLSKRTKAIHKKCPLHEEPYIMFSTEKKSMLCINCFRDMQGESRAHCIDIETAYMQGCEKLDQAVLAVKELQTSTREAIVLLKAMIEEVRNSASEEESAINALFSGMQEQLSDRKKALLKAVQSQHEEKEKAFKEQLAHLASLLPTLQVHLVICSAFLSSANKAEFLDLGYQLMERLQRIVKLPHRLRPAQTSKINTEYRAEFARCLEPLLVLTPRRSVVGSAGGIGPGITGANMIPGSQCSKTLMVPGCPPAGDKMSSSSIVRKPTLHRYISTKVLLAEGRETPFAEHCRNYENTYRMLQTEIQGLKDQVQELHRDLTKHHSLIRTEIMSEILQKSLQMDVQIAAHYSSVEMMRSVFEEVWEETYQRVANEQEIYEAQLHDLLQLRQENSCLTTITKQIAPYVRSIAKVKERLEPRLQEPREPKDEHTQILLRIDDSSEAAQRDSSPGGTDSREQALGSRGGCTPALTPGDPPPKKEHRGSAQRSGTLSADREEPPGSS", "length": 655, "header": "tr|A0A8V0Z8Y1-1|A0A8V0Z8Y1_CHICK Isoform 1 of Ring finger protein 207 OS=Gallus gallus OX=9031 GN=RNF207 PE=4 SV=1 CANONICAL=A0A8V0Z8Y1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1/entry#A0A8V0Z8Y1-1", "sequence": { "sequence": "MQRCRAPEERTEQREEQRGLTQQPPPGSPSTHKVGGVHDAILHRVRAVQRELQHLLLFFATLRCGFLLRDGEREERHPSVVRGGTGLPPVDRLLQFLVDSSAEGSEDAQCANCDRLCAEADLDTMCFCNTCSQPLCAPCREETHRAKVFARHEIVSLSKRTKAIHKKCPLHEEPYIMFSTEKKSMLCINCFRDMQGESRAHCIDIETAYMQGCEKLDQAVLAVKELQTSTREAIVLLKAMIEEVRNSASEEESAINALFSGMQEQLSDRKKALLKAVQSQHEEKEKAFKEQLAHLASLLPTLQVHLVICSAFLSSANKAEFLDLGYQLMERLQRIVKLPHRLRPAQTSKINTEYRAEFARCLEPLLVLTPRRSVVGSAGGIGPGITGANMIPGSQCSKTLMVPGCPPAGDKMSSSSIVRKPTLHRYISTKVLLAEGRETPFAEHCRNYENTYRMLQTEIQGLKDQVQELHRDLTKHHSLIRTEIMSEILQKSLQMDVQIAAHYSSVEMMRSVFEEVWEETYQRVANEQEIYEAQLHDLLQLRQENSCLTTITKQIAPYVRSIAKVKERLEPRLQEPREPKDEHTQILLRIDDSSEAAQRDSSPGGTDSREQALGSRGGCTPALTPGDPPPKKEHRGSAQRSGTLSADREEPPGSS", "length": 655, "header": "tr|A0A8V0Z8Y1-1|A0A8V0Z8Y1_CHICK Isoform 1 of Ring finger protein 207 OS=Gallus gallus OX=9031 GN=RNF207 PE=4 SV=1 CANONICAL=A0A8V0Z8Y1-1" }, "locus": { "chromosome": "21", "start_pos": 631361, "end_pos": 625552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046424.1", "url": "https://www.ensembl.org/id/ENSGALT00010046424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027638.1", "url": "https://www.ensembl.org/id/ENSGALP00010027638.1" } ] } }, { "isoform_ac": "A0A8V0Z9M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1/entry#A0A8V0Z9M1-1", "sequence": { "sequence": "MAGGIFSPLGSCAELEQGAWHPLVCLLCHGPFQQPCLLDCYHAFCASCLRGRAASGRLRCPLCGHPSVVRGGTGLPPVDRLLQFLVDSSAEGSEDAQCANCDRLCAEADLDTMCFCNTCSQPLCAPCREETHRAKVFARHEIVSLSKRTKAIHKKCPLHEEPYIMFSTEKKSMLCINCFRDMQGESRAHCIDIETAYMQGCEKLDQAVLAVKELQTSTREAIVLLKAMIEEVRNSASEEESAINALFSGMQEQLSDRKKALLKAVQSQHEEKEKAFKEQLAHLASLLPTLQVHLVICSAFLSSANKAEFLDLGYQLMERLQRIVKLPHRLRPAQTSKINTEYRAEFARCLEPLLVLTPRRSVVGSAGGIGPGITGANMIPGSQCSKTLMVPGCPPAGDKMSSSSIVRKPTLHRYISTKVLLAEGRETPFAEHCRNYENTYRMLQTEIQGLKDQVQELHRDLTKHHSLIRTEIMSEILQKSLQMDVQIAAHYSSVEMMRSVFEEVWEETYQRVANEQEIYEAQLHDLLQLRQENSCLTTITKQIAPYVRSIAKVKERLEPRLQEPREPKDEHTQILLRIDDSSEAAQRDSSPGGTDSREQALGSRGGCTPALTPGDPPPKKEHRGSAQRSGTLSADREEPPGSS", "length": 643, "header": "tr|A0A8V0Z9M1-1|A0A8V0Z8Y1_CHICK Computationally mapped isoform of Ring finger protein 207 OS=Gallus gallus OX=9031 GN=RNF207 PE=4 SV=1 CANONICAL=A0A8V0Z8Y1-1" }, "locus": { "chromosome": "21", "start_pos": 629959, "end_pos": 625552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046419.1", "url": "https://www.ensembl.org/id/ENSGALT00010046419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027635.1", "url": "https://www.ensembl.org/id/ENSGALP00010027635.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E9QHE3-1", "protein_name": "RING finger protein 207", "gene_name": "rnf207b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGEIFYSVDNLYDLDSANCHPLVCHLCQEQYEHPCLLDCYHTFCASCLRGRVADSRLTCPVCGHQSVVKGINALPPEDRLLKFLVDSSADSEETVQCANCDLECKKQDVDAMYYCNTCCQPLCRDCRETTHKAKMFSRHEIVSLAKRTKEAHKKCALHEEFYIMFSTEKKSMLCINCFRDMQVESRAHCIDIETAYIQGCEKLDQAVLAVKELQMSAREAIILLKAMIGEVRANVDEEESAICTLFSNMQEKLAERKKILLKAARSQHEEKERTFKEQLSHLAALLPTLQVHLVTCSAFLSSANKFEFLDMGYQLMERLKKIVKLPHRLRPTQSSKINTEYRSEFARCLEPLLLLGQRRSMSTTGSVALALGNASGLMQSSLSVQCHSPAMSDMSLCSSVVRRPTSHRYISTKVLLAKGGETPFMEHCCNYENSYRTLQTEIQKLKDQVQEIHRDLTKHHSLTKPDSMSEILEKSVQVDSQISSEYASVELMRAMFEEIWEETLQRVANEQEIYEAQLHDLLQLKQENSYLTTISRQIGPYIRSIAKVKERLEPRLKEPKELKDDRTEIMLKLYEDSTSTADTQPSNELSCNTEDNWTLNSLSEETNPKNKDYYRTNKQKNTTDSTNRKEIPM", "length": 634 }, "evidence": [ { "id": "A0A8V0Z8Y1", "url": "https://omabrowser.org/oma/group/A0A8V0Z8Y1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "id": "GO:1905026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "regulation of cardiac muscle contraction", "id": "GO:0055117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" }, { "name": "regulation of heart looping", "id": "GO:1901207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901207", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Y1" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 157, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9P7-1", "uniprot_ac": "A0A8V0Z9P7", "uniprot_id": "A0A8V0Z9P7_CHICK", "mass": { "chemical_mass": 108179.0, "monoisotopic_mass": 108179.0 }, "refseq": {}, "gene_names": [ { "name": "GRM7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ] } ], "protein_names": [ { "name": "Glutamate metabotropic receptor 7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7", "locus": { "chromosome": "12", "start_pos": 19268738, "end_pos": 19044624, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019426", "url": "https://www.ensembl.org/id/ENSGALG00010019426" } ] } } ], "crossref": [ { "id": "A0A8V0Z9P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15451", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15451", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416112", "url": "https://www.ncbi.nlm.nih.gov/gene/416112", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416112", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416112", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPCGDIR", "url": "https://omabrowser.org/oma/group/MPCGDIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3V1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9P7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Q1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZAF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAF7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24060", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24060", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z3V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAQGGAGQRPGATGSTMLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNKALLHHALGAFLEDSWLKKSHRQKEHIPMVFIIRAGLCLLTGLSGPAAKKKYVSYNNLVI", "length": 973, "header": "tr|A0A8V0Z9P7-1|A0A8V0Z9P7_CHICK Isoform 1 of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#A0A8V0Z3V1-1", "sequence": { "sequence": "MKAQGGAGQRPGATGSTMLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNNCIPPVRKSVQKSVTWYTLPPTV", "length": 936, "header": "tr|A0A8V0Z3V1-1|A0A8V0Z3V1_CHICK Computationally mapped isoform of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "locus": { "chromosome": "12", "start_pos": 19247301, "end_pos": 19044736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046939.1", "url": "https://www.ensembl.org/id/ENSGALT00010046939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027907.1", "url": "https://www.ensembl.org/id/ENSGALP00010027907.1" } ] } }, { "isoform_ac": "A0A8V0Z9P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#A0A8V0Z9P7-1", "sequence": { "sequence": "MKAQGGAGQRPGATGSTMLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNKALLHHALGAFLEDSWLKKSHRQKEHIPMVFIIRAGLCLLTGLSGPAAKKKYVSYNNLVI", "length": 973, "header": "tr|A0A8V0Z9P7-1|A0A8V0Z9P7_CHICK Isoform 1 of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "locus": { "chromosome": "12", "start_pos": 19267633, "end_pos": 19044736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046944.1", "url": "https://www.ensembl.org/id/ENSGALT00010046944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027909.1", "url": "https://www.ensembl.org/id/ENSGALP00010027909.1" } ] } }, { "isoform_ac": "A0A8V0Z9Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#A0A8V0Z9Q1-1", "sequence": { "sequence": "MKAQGGAGQRPGATGSTMLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKALLQKRSTSVITTWLSSPLRHGHEDGEDFHLLRAQASSRPRHEQRPGRAGSCCPTATPCARQGLGGEVWAWGRGLALLRHGAAELTAREERSPALRGLTGAVLSFYVLPDCKFLNFLYSL", "length": 951, "header": "tr|A0A8V0Z9Q1-1|A0A8V0Z9Q1_CHICK Computationally mapped isoform of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "locus": { "chromosome": "12", "start_pos": 19267946, "end_pos": 19044736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046955.1", "url": "https://www.ensembl.org/id/ENSGALT00010046955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027914.1", "url": "https://www.ensembl.org/id/ENSGALP00010027914.1" } ] } }, { "isoform_ac": "A0A8V0ZAF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#A0A8V0ZAF2-1", "sequence": { "sequence": "MLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKGKESVLSSTCISKGGDFCWKGALPHFSSTYKLPHLQYP", "length": 852, "header": "tr|A0A8V0ZAF2-1|A0A8V0ZAF2_CHICK Computationally mapped isoform of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "locus": { "chromosome": "12", "start_pos": 19242489, "end_pos": 19044787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046935.1", "url": "https://www.ensembl.org/id/ENSGALT00010046935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027906.1", "url": "https://www.ensembl.org/id/ENSGALP00010027906.1" } ] } }, { "isoform_ac": "A0A8V0ZAF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7/entry#A0A8V0ZAF7-1", "sequence": { "sequence": "MKAQGGAGQRPGATGSTMLRLGRLLRLLTLVKLPCCLLEFLLSEAALGQEMYAPHSIRLEGDITLGGLFPVHAKGPPGVPCGDIKKENGIHRLEAMLYALDQINSDPELLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGNYGEKGVESFMQISREAGGLCIAQSLKIPQDRKDKTIDFDKIIKQLLETPNARAIVIFANDEDIKQILAAAKRADQVGHFLWVGSDTWGSKVSPLLQQEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTITGSKKEDTDRKCTGQERIGKDSHYEQEGKVQFVIDAVYAMAHALHHMSKDLCADYAGVCPEMEHAGGKKLLKYIRSVNFNGSAGTPVMFNKNGDAPGRYDIFQYHTTNTSTPGYRLVGQWTDDLQLNIDDMQWGKGVREVPSSVCSLPCKPGERKKMVKGMPCCWHCELCDGYQYQADEVTCLLCSYNERPNENRTGCRSIPIVKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPNVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFAVDPPNIIIDYDEQKTMNPDQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI", "length": 929, "header": "tr|A0A8V0ZAF7-1|A0A8V0Z9P7_CHICK Computationally mapped isoform of Glutamate metabotropic receptor 7 OS=Gallus gallus OX=9031 GN=GRM7 PE=3 SV=1 CANONICAL=A0A8V0Z9P7-1" }, "locus": { "chromosome": "12", "start_pos": 19267633, "end_pos": 19044736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046950.1", "url": "https://www.ensembl.org/id/ENSGALT00010046950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027911.1", "url": "https://www.ensembl.org/id/ENSGALP00010027911.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416112", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416112", "resource": "KEGG Pathway" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-GGA-420499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420499", "resource": "Reactome", "description": "Class C/3 (Metabotropic glutamate/pheromone receptors)" } ], "orthologs": [ { "uniprot_canonical_ac": "Q68ED2-1", "protein_name": "Metabotropic glutamate receptor 7", "gene_name": "Grm7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPPSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI", "length": 915 }, "evidence": [ { "id": "A0A8V0Z9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "group III metabotropic glutamate receptor activity", "id": "GO:0001642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "adenylate cyclase inhibitor activity", "id": "GO:0010855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010855", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "serine binding", "id": "GO:0070905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" }, { "name": "G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P7" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 604, "end_pos": 878, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBF9-1", "uniprot_ac": "A0A8V0ZBF9", "uniprot_id": "A0A8V0ZBF9_CHICK", "mass": { "chemical_mass": 66229.0, "monoisotopic_mass": 66229.0 }, "refseq": {}, "gene_names": [ { "name": "CD5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" } ] } ], "protein_names": [ { "name": "CD5 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9", "locus": { "chromosome": "5", "start_pos": 252707, "end_pos": 247469, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019580", "url": "https://www.ensembl.org/id/ENSGALG00010019580" } ] } } ], "crossref": [ { "id": "A0A8V0ZBF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "395757", "url": "https://www.ncbi.nlm.nih.gov/gene/395757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395757", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395757", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCSGFQP", "url": "https://omabrowser.org/oma/group/VCSGFQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z442", "url": "https://www.orthodb.org/?gene=A0A8V0Z442", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZAQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z442", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z442", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z442-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z442-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCGRERGVMRLEMGRGWEQEWGQEGQEMGMGMEMRMERGSDGDREGDGMSVGSEMRYSAPLSLWLCPWRGSCQDATSDEEDVTQKPQREEKQPVAACPPHPPPRPPFPRLGTEALLLHAPPAQPPAPGRRRQHGPMAARPPALCLLLVVGMWAGCGQRGAVLGAAEKPLRLSGGGCRCAGLLEVQMLSRWSPVCWDGVSPGSVCEQLGCRPPAKLSSAPPDLEEQQAWAMQCKGMERCQWKAANCSQLAVVTCSEPEPTSTKPPSVPPTTSPEPTGAPWLRLVDGNFSCSGFVELHLRGRWGAVALSPDVWPELPARICRELGCNNPSGVPMGGPMGGPVSLPPQSRLPVRWEAVAPCSSPELLDCFNWTSHGHGKASAFLICPGSQPRAGRRLAGGPTPCEGHIEVFQRGQWHTLCDEQAHRVERGHQLCRELRCGDLSSSAELQEPRAGGVICKERYLHLCPESPEEVHGCSRTHVVCQKSKPPPAGTAPGTVASICLALLLLGVLLLICGPPAYRRLMKRISKKKQRQWIGPTGLHQSVSFHRNSTVTPRVRVEEQQRARRGDNDYAQPPQKSPSAYPALEGAARASGAPDNSSDSDYDLHSAHRL", "length": 610, "header": "tr|A0A8V0ZBF9-1|A0A8V0ZBF9_CHICK Isoform 1 of CD5 molecule OS=Gallus gallus OX=9031 GN=CD5 PE=4 SV=1 CANONICAL=A0A8V0ZBF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z442-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9/entry#A0A8V0Z442-1", "sequence": { "sequence": "METGKEMGCRGAVDGMGMSVGSEMRYSAPLSLWLCPWRGSCQDATSDEEDVTQKPQREEKQPVAACPPHPPPRPPFPRLGTEALLLHAPPAQPPAPGRRRQHGPMAARPPALCLLLVVGMWAGCGQRGAVLGAAEKPLRLSGGGCRCAGLLEVQMLSRWSPVCWDGVSPGSVCEQLGCRPPAKLSSAPPDLEEQQAWAMQCKGMERCQWKAANCSQLAVVTCSEPEPTSTKPPSVPPTTSPEPTGAPWLRLVDGNFSCSGFVELHLRGRWGAVALSPDVWPELPARICRELGCNNPSGVPMGGPMGGPVSLPPQSRLPVRWEAVAPCSSPELLDCFNWTSHGHGKASAFLICPGSQPRAGRRLAGGPTPCEGHIEVFQRGQWHTLCDEQAHRVERGHQLCRELRCGDLSSSAELQEPRAGGVICKERYLHLCPESPEEVHGCSRTHVVCQKSKPPPAGTAPGTVASICLALLLLGVLLLICGPPAYRRLMKRISKKKQRQWIGPTGLHQSVSFHRNSTVTPRVRVEEQQRARRGDNDYAQPPQKSPSAYPGCDMQR", "length": 556, "header": "tr|A0A8V0Z442-1|A0A8V0Z442_CHICK Computationally mapped isoform of CD5 molecule OS=Gallus gallus OX=9031 GN=CD5 PE=4 SV=1 CANONICAL=A0A8V0ZBF9-1" }, "locus": { "chromosome": "5", "start_pos": 251703, "end_pos": 248496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047230.1", "url": "https://www.ensembl.org/id/ENSGALT00010047230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027997.1", "url": "https://www.ensembl.org/id/ENSGALP00010027997.1" } ] } }, { "isoform_ac": "A0A8V0ZAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9/entry#A0A8V0ZAQ6-1", "sequence": { "sequence": "MAARPPALCLLLVVGMWAGCGQRGAVLGAAEKPLRLSGGGCRCAGLLEVQMLSRWSPVCWDGVSPGSVCEQLGCRPPAKLSSAPPDLEEQQAWAMQCKGMERCQWKAANCSQLAVVTCSEPEPTSTKPPSVPPTTSPEPTGAPWLRLVDGNFSCSGFVELHLRGRWGAVALSPDVWPELPARICRELGCNNPSGVPMGGPMGGPVSLPPQSRLPVRWEAVAPCSSPELLDCFNWTSHGHGKASAFLICPGSQPRAGRRLAGGPTPCEGHIEVFQRGQWHTLCDEQAHRVERGHQLCRELRCGDLSSSAELQEPRAGGVICKERYLHLCPESPEEVHGCSRTHVVCQKSKPPPAGTAPGTVASICLALLLLGVLLLICGPPAYRRLMKRISKKKQRQWIGPTGLHQSVSFHRNSTVTPRVRVEEQQRARRGDNDYAQPPQKSPSAYPALEGAARASGAPDNSSDSDYDLHSAHRL", "length": 474, "header": "tr|A0A8V0ZAQ6-1|A0A8V0ZBF9_CHICK Computationally mapped isoform of CD5 molecule OS=Gallus gallus OX=9031 GN=CD5 PE=4 SV=1 CANONICAL=A0A8V0ZBF9-1" }, "locus": { "chromosome": "5", "start_pos": 251690, "end_pos": 248808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047240.1", "url": "https://www.ensembl.org/id/ENSGALT00010047240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028001.1", "url": "https://www.ensembl.org/id/ENSGALP00010028001.1" } ] } }, { "isoform_ac": "A0A8V0ZBF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9/entry#A0A8V0ZBF9-1", "sequence": { "sequence": "MRCGRERGVMRLEMGRGWEQEWGQEGQEMGMGMEMRMERGSDGDREGDGMSVGSEMRYSAPLSLWLCPWRGSCQDATSDEEDVTQKPQREEKQPVAACPPHPPPRPPFPRLGTEALLLHAPPAQPPAPGRRRQHGPMAARPPALCLLLVVGMWAGCGQRGAVLGAAEKPLRLSGGGCRCAGLLEVQMLSRWSPVCWDGVSPGSVCEQLGCRPPAKLSSAPPDLEEQQAWAMQCKGMERCQWKAANCSQLAVVTCSEPEPTSTKPPSVPPTTSPEPTGAPWLRLVDGNFSCSGFVELHLRGRWGAVALSPDVWPELPARICRELGCNNPSGVPMGGPMGGPVSLPPQSRLPVRWEAVAPCSSPELLDCFNWTSHGHGKASAFLICPGSQPRAGRRLAGGPTPCEGHIEVFQRGQWHTLCDEQAHRVERGHQLCRELRCGDLSSSAELQEPRAGGVICKERYLHLCPESPEEVHGCSRTHVVCQKSKPPPAGTAPGTVASICLALLLLGVLLLICGPPAYRRLMKRISKKKQRQWIGPTGLHQSVSFHRNSTVTPRVRVEEQQRARRGDNDYAQPPQKSPSAYPALEGAARASGAPDNSSDSDYDLHSAHRL", "length": 610, "header": "tr|A0A8V0ZBF9-1|A0A8V0ZBF9_CHICK Isoform 1 of CD5 molecule OS=Gallus gallus OX=9031 GN=CD5 PE=4 SV=1 CANONICAL=A0A8V0ZBF9-1" }, "locus": { "chromosome": "5", "start_pos": 251690, "end_pos": 248372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047223.1", "url": "https://www.ensembl.org/id/ENSGALT00010047223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027995.1", "url": "https://www.ensembl.org/id/ENSGALP00010027995.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395757", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P06127-1", "protein_name": "T-cell surface glycoprotein CD5", "gene_name": "CD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPDNSSDSDYDLHGAQRL", "length": 495 }, "evidence": [ { "id": "A0A8V0ZBF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13379-1", "protein_name": "T-cell surface glycoprotein CD5", "gene_name": "Cd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSHEVLLAATYLLGTLAAFCLGQSGRGGLDIQVMLSGSNSKCQGQVEIQMENKWKTVCSSSWRLSQDHSKNAQQASAVCKQLRCGDPLALGPFPSLNRPQNQVFCQGSPWSISNCNNTSSQDQCLPLSLICLEPQRTTPPPTTTPPTTVPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSWGGTILYKAKDRPLGLGNLICKSLQCGSFLTHLSGTEAAGTPAPAELRDPRPLPIRWEAPNGSCVSLQQCFQKTTAQEGGQALTVICSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWEALCDSSAARGRGRWEELCREQQCGDLISFHTVDADKTSPGFLCAQEKLSQCYHLQKKKHCNKRVFVTCQDPNPAGLAPGTVASIILTLVLLVVLLAMCGPLVYKKLVKKFRQKKQRQWIGPTGVNQNMSFHRSHTATVRSQVENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSTQPDNSSDSDYDLQVAQRL", "length": 494 }, "evidence": [ { "id": "A0A8V0ZBF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19238-1", "protein_name": "T-cell surface glycoprotein CD5", "gene_name": "CD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSQHLPLAALYLLELLVTSCLGGLKVEVQGLTMRLSGSGSRCQGRLEVSNGTEWYAVHSQSWGQLSLYQVAPRQFLKLCQELQCRDPLLLSSSRYFKEVQFQKLIICHGQLGSFSNCSLNRGRQVDSLALICLEPPRTTAPPTTSPPTTTPEPTAPPRFQLVAEPGGLRCAGVVEFYSGGLGGTIGIEPQNDIKDLGQLICAALQCGSFLKPLPETEEAQTQKPEGQRPLPIRWEIQNPKCTSLEQCFRKVQPWVGGQALGLICSDFQPKVQSRLVGGSDVCEGSVEVRSGKGQKWDTLCDDSWAKGTARWEEVCREQQCGNVSSYRGLDPSEKTLGGFYCPPGILSRCHKLEEKKSHCKRVFVTCQNSSRAGLGAGAVMSIILALLLLAVLLVVCGPLAYKKVVKKFRQKKQRQWIGPTGMNQNMSFHRNHTVTVRSQVENATASHVENEYSQPPRNSQISAYPALEGALHRISTQPDNSSDSDYELHGAQRL", "length": 495 }, "evidence": [ { "id": "A0A8V0ZBF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P51882-1", "protein_name": "T-cell surface glycoprotein CD5", "gene_name": "Cd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSHEVLLAATYLLGTLAAFCLGQSGRGFVGAQVMLSGSNSKCQGLVEVQMNGMKTVCSSSWRLSQDLWKNANEASTVCQQLGCGNPLALGHLTLWNRPKNQILCQGPPWSFSNCSTSSLGQCLPLSLVCLEPQKTTPLPTTTLPTTMPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSRGGTILYKAKARPVDLGNLICKSLQCGSFLTHLSRIETAGTPAPAELRDPRPLPIRWEAQNGSCTSLQQCFQKTTVQEGSQALAVVCSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWAALCDSSAARGPGRWEELCQEQQCGNLISFHVMDADRTSPGVLCTQEKLSQCYQLQKKTHCKRVFITCKDPNPVGLAPGTVASIILTLVLLVVLMVMCGPLIYKKLVKKFRQKKQRQWIGPTGVNQSMSFHRSHTATVRSQVENPAASHVDNEYSQPPRNSRLSAYPALEGALHRSSTQPDNSSDSDYDLQVAQRL", "length": 491 }, "evidence": [ { "id": "A0A8V0ZBF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "T cell costimulation", "id": "GO:0031295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBF9" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 255, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 400 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8C5-1", "uniprot_ac": "A0A8V0Z8C5", "uniprot_id": "A0A8V0Z8C5_CHICK", "mass": { "chemical_mass": 58679.0, "monoisotopic_mass": 58679.0 }, "refseq": {}, "gene_names": [ { "name": "EFEMP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ] } ], "protein_names": [ { "name": "EGF-containing fibulin-like extracellular matrix protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5/entry#names_and_taxonomy" } ] }, { "name": "Fibulin-3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P380", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P380#function" }, { "database": "UniProtKB", "id": "ARBA00054842", "url": "https://www.uniprot.org/uniprotkb/ARBA00054842#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFEMP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5", "locus": { "chromosome": "3", "start_pos": 330153, "end_pos": 383963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018885", "url": "https://www.ensembl.org/id/ENSGALG00010018885" } ] } } ], "crossref": [ { "id": "A0A8V0Z8C5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037901", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037901", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428543", "url": "https://www.ncbi.nlm.nih.gov/gene/428543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428543", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CETRNEC", "url": "https://omabrowser.org/oma/group/CETRNEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P380", "url": "https://www.orthodb.org/?gene=A0A1D5P380", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P380", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P380", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P380-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P380-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGRTAPFAVFLRPFFPCCFLHYWHRLTQGGGGVTIPGGVREEGWIGRSGLAALPGLPLSCRSGRGCVLAAVPRFMMLTAMFLAALILITVHSQETEETITYTQCTDGYEWDPVRQRCKDIDECEIVPDACKGGMKCVNHYGGYLCLPRTAQIIVNEREEAAAESTSGRNNVIRRTPADPHRAPPNPTHQIQCAAGYEQSEHNVCQDIDECATGTHNCRADQVCVNLRGSFSCQCPPGYQKRGEQCVDIDECTLPPYCHHRCVNTPGSYYCQCNAGFQLASNNHTCVDINECDANNPCAQQCYNILGSFICQCNPGFELSSDRINCEDTDECRTSSYICQYQCVNEPGKFSCVCPEGYQVVGGRTCQDINECETTNECREDEICWNYHGGFRCYPINPCQEPYVLTSENRCVCPVSNTICRELPYSVVYKYMSIRSDRTVPSDIFQIQATTIYPNTINTFRIKSGNENGEFYLRQTSAVSAMLVLVKSLSGPREHIVDLEMLTVNSLNYRTSSVLRLTIIVGPYAF", "length": 526, "header": "tr|A0A8V0Z8C5-1|A0A8V0Z8C5_CHICK Isoform 1 of EGF-containing fibulin-like extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=EFEMP1 PE=1 SV=1 CANONICAL=A0A8V0Z8C5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P380-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5/entry#A0A1D5P380-1", "sequence": { "sequence": "MMLTAMFLAALILITVHSQETEETITYTQCTDGYEWDPVRQRCKDIDECEIVPDACKGGMKCVNHYGGYLCLPRTAQIIVNEREEAAAESTSGRNNVIRRTPADPHRAPPNPTHQIQCAAGYEQSEHNVCQDIDECATGTHNCRADQVCVNLRGSFSCQCPPGYQKRGEQCVDIDECTLPPYCHHRCVNTPGSYYCQCNAGFQLASNNHTCVDINECDANNPCAQQCYNILGSFICQCNPGFELSSDRINCEDTDECRTSSYICQYQCVNEPGKFSCVCPEGYQVVGGRTCQDINECETTNECREDEICWNYHGGFRCYPINPCQEPYVLTSENRCVCPVSNTICRELPYSVVYKYMSIRSDRTVPSDIFQIQATTIYPNTINTFRIKSGNENGEFYLRQTSAVSAMLVLVKSLSGPREHIVDLEMLTVNSLNYRTSSVLRLTIIVGPYAF", "length": 451, "header": "tr|A0A1D5P380-1|A0A8V0Z8C5_CHICK Computationally mapped isoform of EGF-containing fibulin-like extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=EFEMP1 PE=1 SV=2 CANONICAL=A0A8V0Z8C5-1" }, "locus": { "chromosome": "3", "start_pos": 382317, "end_pos": 331209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045652.1", "url": "https://www.ensembl.org/id/ENSGALT00010045652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027220.1", "url": "https://www.ensembl.org/id/ENSGALP00010027220.1" } ] } }, { "isoform_ac": "A0A8V0Z8C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5/entry#A0A8V0Z8C5-1", "sequence": { "sequence": "MLGRTAPFAVFLRPFFPCCFLHYWHRLTQGGGGVTIPGGVREEGWIGRSGLAALPGLPLSCRSGRGCVLAAVPRFMMLTAMFLAALILITVHSQETEETITYTQCTDGYEWDPVRQRCKDIDECEIVPDACKGGMKCVNHYGGYLCLPRTAQIIVNEREEAAAESTSGRNNVIRRTPADPHRAPPNPTHQIQCAAGYEQSEHNVCQDIDECATGTHNCRADQVCVNLRGSFSCQCPPGYQKRGEQCVDIDECTLPPYCHHRCVNTPGSYYCQCNAGFQLASNNHTCVDINECDANNPCAQQCYNILGSFICQCNPGFELSSDRINCEDTDECRTSSYICQYQCVNEPGKFSCVCPEGYQVVGGRTCQDINECETTNECREDEICWNYHGGFRCYPINPCQEPYVLTSENRCVCPVSNTICRELPYSVVYKYMSIRSDRTVPSDIFQIQATTIYPNTINTFRIKSGNENGEFYLRQTSAVSAMLVLVKSLSGPREHIVDLEMLTVNSLNYRTSSVLRLTIIVGPYAF", "length": 526, "header": "tr|A0A8V0Z8C5-1|A0A8V0Z8C5_CHICK Isoform 1 of EGF-containing fibulin-like extracellular matrix protein 1 OS=Gallus gallus OX=9031 GN=EFEMP1 PE=1 SV=1 CANONICAL=A0A8V0Z8C5-1" }, "locus": { "chromosome": "3", "start_pos": 383913, "end_pos": 331209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045658.1", "url": "https://www.ensembl.org/id/ENSGALT00010045658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027222.1", "url": "https://www.ensembl.org/id/ENSGALP00010027222.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428543", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IL08-1", "protein_name": "Uncharacterized protein LOC563864 precursor", "gene_name": "si:ch73-173h19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLGICLCLSVAVHFAVSQEAEAQEPVTYTASRPTFDEHDIYERELWELFDCLCTEGYEFDFEKQICKDIDECKTVLEACKGGMKCINHFGGYLCLPHNARIIVSNGEGEPTTAPPVERFQPVIPQISRGEFSRVIQSSSHSIQCGVGFMADSQNYCRDVNECLTANPCQHQCYNLMGSYICQCEVGFELASDSVSCQDINECEISNYICQFQCVNEPGAFHCACPEGYQLQGPRMCQDIDECETGAHNCREDEMCWNYYGGFRCYPRDPCREPYVKTGEGRCRCQSQTVCRGLPPVIVYKYMSIFSDRSVPADIFQIQATSVYPNMVNTFTIKNGNEGGEFYLRRSSNVSAMLVMTKPLTGPREHVVDLEMVTQSNVLSYRSSSLLRLTIVVGPYPF", "length": 397 }, "evidence": [ { "id": "A0A8V0Z8C5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287AP71-1", "protein_name": "EGF-containing fibulin-like extracellular matrix protein 1", "gene_name": "EFEMP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FCLKKKSLRPRFTMLKVLFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPAAEGVGAAANAAAASGAGTGGVAASGMATSAVVPGGGFVASAAAEVQTSRNNFVIRRNPADPQRIPSNPSHRIQCATGYEQSEHNVCQDIDECTAGTHSCRADQVCINLRGSFTCQCPPGYQKRGEQCVDVDECSIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYVLTSENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVNSIGTFRTSSVLRLTIIVGPFSF", "length": 511 }, "evidence": [ { "id": "A0A8V0Z8C5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35568-1", "protein_name": "EGF-containing fibulin-like extracellular matrix protein 1", "gene_name": "Efemp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQTVFLTMLTLALVKSQVTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPAAEASSGAATGTIAARSMATSGVIPGGGFIASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRLDQVCINLRGSFTCHCLPGYQKRGEQCVDIDECSVPPYCHQGCVNTPGSFYCQCNPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPQNPCQDPYVLTSENRCVCPVSNTMCRDVPQSIVYKYMNIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLTGPREHIVGLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "length": 493 }, "evidence": [ { "id": "A0A8V0Z8C5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12805-1", "protein_name": "EGF-containing fibulin-like extracellular matrix protein 1", "gene_name": "EFEMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "length": 493 }, "evidence": [ { "id": "A0A8V0Z8C5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BPB5-1", "protein_name": "EGF-containing fibulin-like extracellular matrix protein 1", "gene_name": "Efemp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "length": 493 }, "evidence": [ { "id": "A0A8V0Z8C5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "epidermal growth factor receptor activity", "id": "GO:0005006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "embryonic eye morphogenesis", "id": "GO:0048048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "negative regulation of chondrocyte differentiation", "id": "GO:0032331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "post-embryonic eye morphogenesis", "id": "GO:0048050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C5" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 247, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7S3-1", "uniprot_ac": "A0A8V0Z7S3", "uniprot_id": "A0A8V0Z7S3_CHICK", "mass": { "chemical_mass": 33633.0, "monoisotopic_mass": 33633.0 }, "refseq": {}, "gene_names": [ { "name": "SRSF5A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ] } ], "protein_names": [ { "name": "Serine/arginine-rich splicing factor 5a", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRSF5A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3", "locus": { "chromosome": "5", "start_pos": 27835580, "end_pos": 27819004, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020530", "url": "https://www.ensembl.org/id/ENSGALG00010020530" } ] } } ], "crossref": [ { "id": "A0A8V0Z7S3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7S3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033259", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12600", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12600", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423265", "url": "https://www.ncbi.nlm.nih.gov/gene/423265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423265", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRRGPPD", "url": "https://omabrowser.org/oma/group/MRRGPPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P407", "url": "https://www.orthodb.org/?gene=A0A1D5P407", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7S3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEL2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P407", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P407", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P407-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P407-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGCRVFVGHLSSRARERDVEKFFKGYGRIREIHLKNGFGFVEFEDHRDADDAIYELNGKELCDERVTIEHARARRGRGRFAQRFSYYSQSGSSRYGPPVRTEHRIIVENLSSRISWQVPYVICHLWRAADLKDVMRKAGEVTYVDAHRNNRNEGVVEFASYSDMKSALEKLDGTELNGRRIKLIEDHRRHRSRSRSRSYSRSRSKSKSTGSSRSYSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRTPKKSYSQKSHRSSLPASSPSPSSSKRKSRSRSSSAHSRS", "length": 290, "header": "tr|A0A8V0Z7S3-1|A0A8V0Z7S3_CHICK Isoform 1 of Serine/arginine-rich splicing factor 5a OS=Gallus gallus OX=9031 GN=SRSF5A PE=1 SV=1 CANONICAL=A0A8V0Z7S3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P407-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3/entry#A0A1D5P407-1", "sequence": { "sequence": "MSGCRVFVGHLSSRARERDVEKFFKGYGRIREIHLKNGFGFVEFEDHRDADDAIYELNGKELCDERVTIEHARARRGRGRFAQRFSYYSQSGSSRYGPPVRTEHRIIVENLSSRISWQDLKDVMRKAGEVTYVDAHRNNRNEGVVEFASYSDMKSALEKLDGTELNGRRIKLIEDHRRHRSRSRSRSYSRSRSKSKSTGSSRSYSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRTPKKSYSQKSHRSSLPASSPSPSSSKRKSRSRSSSAHSRS", "length": 278, "header": "tr|A0A1D5P407-1|A0A8V0Z7S3_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 5a OS=Gallus gallus OX=9031 GN=SRSF5A PE=1 SV=1 CANONICAL=A0A8V0Z7S3-1" }, "locus": { "chromosome": "5", "start_pos": 27834341, "end_pos": 27821332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049594.1", "url": "https://www.ensembl.org/id/ENSGALT00010049594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029297.1", "url": "https://www.ensembl.org/id/ENSGALP00010029297.1" } ] } }, { "isoform_ac": "A0A8V0Z7S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3/entry#A0A8V0Z7S3-1", "sequence": { "sequence": "MSGCRVFVGHLSSRARERDVEKFFKGYGRIREIHLKNGFGFVEFEDHRDADDAIYELNGKELCDERVTIEHARARRGRGRFAQRFSYYSQSGSSRYGPPVRTEHRIIVENLSSRISWQVPYVICHLWRAADLKDVMRKAGEVTYVDAHRNNRNEGVVEFASYSDMKSALEKLDGTELNGRRIKLIEDHRRHRSRSRSRSYSRSRSKSKSTGSSRSYSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRTPKKSYSQKSHRSSLPASSPSPSSSKRKSRSRSSSAHSRS", "length": 290, "header": "tr|A0A8V0Z7S3-1|A0A8V0Z7S3_CHICK Isoform 1 of Serine/arginine-rich splicing factor 5a OS=Gallus gallus OX=9031 GN=SRSF5A PE=1 SV=1 CANONICAL=A0A8V0Z7S3-1" }, "locus": { "chromosome": "5", "start_pos": 27834341, "end_pos": 27821332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049590.1", "url": "https://www.ensembl.org/id/ENSGALT00010049590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029294.1", "url": "https://www.ensembl.org/id/ENSGALP00010029294.1" } ] } }, { "isoform_ac": "A0A8V0ZDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3/entry#A0A8V0ZDJ5-1", "sequence": { "sequence": "MSGCRVFVGHLSSRARERDVEKFFKGYGRIREIHLKNGFGFVEFEDHRDADDAIYELNGKELCDERVTIEHARARRGRGRFAQRFSYYSQSGSSRYGPPVRTEHRIIVENLSSRISWQDLKDVMRKAGEVTYVDAHRNNRNEGVVEFASYSDMKSALEKLDGTELNGRRIKLIEDHRRHRSRSRSRSYSRSRSKSKSTGSSRSYSRSRSRSRSRSRSRSRSRSRSRSRSRTPKKSYSQKSHRSSLPASSPSPSSSKRKSRSRSSSAHSRS", "length": 270, "header": "tr|A0A8V0ZDJ5-1|A0A8V0ZDJ5_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 5a OS=Gallus gallus OX=9031 GN=SRSF5A PE=1 SV=1 CANONICAL=A0A8V0Z7S3-1" }, "locus": { "chromosome": "5", "start_pos": 27834341, "end_pos": 27821332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049584.1", "url": "https://www.ensembl.org/id/ENSGALT00010049584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029291.1", "url": "https://www.ensembl.org/id/ENSGALP00010029291.1" } ] } }, { "isoform_ac": "A0A8V0ZEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3/entry#A0A8V0ZEL2-1", "sequence": { "sequence": "MSGCRVFVGHLSSRARERDVEKFFKGYGRIREIHLKNGFGFVEFEDHRDADDAIYELNGKELCDERVTIEHARARRGRGRFAQRFSYYSQSGSSRYGPPVRTEHRIIVENLSSRISWQDLKDVMRKAGEVTYVDAHRNNRNEGVVEFASYSDMKSALEKLDGTELNGRRIKLIEDHRRHRSRSRSYSRSRSKSKSTGSSRSYSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRSRTPKKSYSQKSHRSSLPASSPSPSSSKRKSRSRSSSAHSRS", "length": 276, "header": "tr|A0A8V0ZEL2-1|A0A8V0ZEL2_CHICK Computationally mapped isoform of Serine/arginine-rich splicing factor 5a OS=Gallus gallus OX=9031 GN=SRSF5A PE=1 SV=1 CANONICAL=A0A8V0Z7S3-1" }, "locus": { "chromosome": "5", "start_pos": 27834341, "end_pos": 27821332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049587.1", "url": "https://www.ensembl.org/id/ENSGALT00010049587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029293.1", "url": "https://www.ensembl.org/id/ENSGALP00010029293.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423265", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S3" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 74, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8F9-1", "uniprot_ac": "A0A8V0Z8F9", "uniprot_id": "A0A8V0Z8F9_CHICK", "mass": { "chemical_mass": 40744.0, "monoisotopic_mass": 40744.0 }, "refseq": {}, "gene_names": [ { "name": "NUDCD3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ] } ], "protein_names": [ { "name": "NudC domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUDCD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9", "locus": { "chromosome": "22", "start_pos": 4519073, "end_pos": 4502102, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018611", "url": "https://www.ensembl.org/id/ENSGALG00010018611" } ] } } ], "crossref": [ { "id": "A0A8V0Z8F9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8F9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038299", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038299", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06495", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06495", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770002", "url": "https://www.ncbi.nlm.nih.gov/gene/770002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770002", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770002", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EINIEMP", "url": "https://omabrowser.org/oma/group/EINIEMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PY00", "url": "https://www.orthodb.org/?gene=A0A1D5PY00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8F9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12356:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12356:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PY00", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PY00-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PY00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALTEMYDQALLGILQHVGNVDDFLRVLFGFLYRKTDFYRLLLRPGDRLGFPPGAAQAMALQAFKVFERMARQDDEKRRRELEAKLRKKEEEEEAAASAERVRVAPAAHEVEVETTEEPEPSLDAGGAEGPQDSPATLAAASPVPAEPPGAAAPAQPSPAELPTGQEQFQTNPDSYNGAVRENYAWSQDYSDLEIKVPVPKHIVKGKQVSVDISSSTIRVAVLEGSSQRVLMEGKLTHKINTESSLWSLEPGKCVLVRAALSLPRLAAPRCLAWKMGAAGGLSQSWLRPTLPFPGCPCRTCSSCVPGKGKPHCLFLCCPGVLTRCWSCWKQSVQLLLFAFCMSSSSRWFGGSSSLLDLLPHGELLLAVGVSGVL", "length": 375, "header": "tr|A0A8V0Z8F9-1|A0A8V0Z8F9_CHICK Isoform 1 of NudC domain-containing protein 3 OS=Gallus gallus OX=9031 GN=NUDCD3 PE=1 SV=1 CANONICAL=A0A8V0Z8F9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PY00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9/entry#A0A1D5PY00-1", "sequence": { "sequence": "MEALTEMYDQALLGILQHVGNVDDFLRVLFGFLYRKTDFYRLLLRPGDRLGFPPGAAQAMALQAFKVFERMARQDDEKRRRELEAKLRKKEEEEEAAASAERVRVAPAAHEVEVETTEEPEPSLDAGGAEGPQDSPATLAAASPVPAEPPGAAAPAQPSPAELPTGQEQFQTNPDSYNGAVRENYAWSQDYSDLEIKVPVPKHIVKGKQVSVDISSSTIRVAVLEGSSQRVLMEGKLTHKINTESSLWSLEPGKCVLINLNKGDEYWWNAVLEGEEQIDIDKINKERSMATVDEEEHAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDTEGSPFRGQKFDPSMFNISPGAVQF", "length": 356, "header": "tr|A0A1D5PY00-1|A0A8V0Z8F9_CHICK Computationally mapped isoform of NudC domain-containing protein 3 OS=Gallus gallus OX=9031 GN=NUDCD3 PE=1 SV=2 CANONICAL=A0A8V0Z8F9-1" }, "locus": { "chromosome": "22", "start_pos": 4518601, "end_pos": 4502151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045032.1", "url": "https://www.ensembl.org/id/ENSGALT00010045032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026903.1", "url": "https://www.ensembl.org/id/ENSGALP00010026903.1" } ] } }, { "isoform_ac": "A0A8V0Z8F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9/entry#A0A8V0Z8F9-1", "sequence": { "sequence": "MEALTEMYDQALLGILQHVGNVDDFLRVLFGFLYRKTDFYRLLLRPGDRLGFPPGAAQAMALQAFKVFERMARQDDEKRRRELEAKLRKKEEEEEAAASAERVRVAPAAHEVEVETTEEPEPSLDAGGAEGPQDSPATLAAASPVPAEPPGAAAPAQPSPAELPTGQEQFQTNPDSYNGAVRENYAWSQDYSDLEIKVPVPKHIVKGKQVSVDISSSTIRVAVLEGSSQRVLMEGKLTHKINTESSLWSLEPGKCVLVRAALSLPRLAAPRCLAWKMGAAGGLSQSWLRPTLPFPGCPCRTCSSCVPGKGKPHCLFLCCPGVLTRCWSCWKQSVQLLLFAFCMSSSSRWFGGSSSLLDLLPHGELLLAVGVSGVL", "length": 375, "header": "tr|A0A8V0Z8F9-1|A0A8V0Z8F9_CHICK Isoform 1 of NudC domain-containing protein 3 OS=Gallus gallus OX=9031 GN=NUDCD3 PE=1 SV=1 CANONICAL=A0A8V0Z8F9-1" }, "locus": { "chromosome": "22", "start_pos": 4514595, "end_pos": 4502151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045029.1", "url": "https://www.ensembl.org/id/ENSGALT00010045029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026900.1", "url": "https://www.ensembl.org/id/ENSGALP00010026900.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770002", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770002", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A4I4-1", "protein_name": "NudC domain-containing protein 3", "gene_name": "Nudcd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPTDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRKKELEEKIRKKEEEAKAVAAATAEKEAVPVPVQEVEIDATTALSGPREVEKEELPGPQGPERKVTHGSEEAEAPGTASSAAEGPKDPPVLPRIQEQFQKNPDSYNGAIRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSGSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF", "length": 363 }, "evidence": [ { "id": "A0A8V0Z8F9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HMA9-1", "protein_name": "NudC domain-containing protein 3", "gene_name": "Nudcd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRKKELEEKIRKKEEEAKAVAAAAAEKEAVPVPVQEVEIDATAELSGPREVEKLESPGPQGPDHKVAHGLEEAEAPGTVSSAAEGPKEPPVLPRIQEQFQKNPDSYNGAIRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSGSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGRCVLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF", "length": 363 }, "evidence": [ { "id": "A0A8V0Z8F9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8IVD9-1", "protein_name": "NudC domain-containing protein 3", "gene_name": "NUDCD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF", "length": 361 }, "evidence": [ { "id": "A0A8V0Z8F9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1N4-1", "protein_name": "NudC domain-containing protein 3", "gene_name": "Nudcd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRKKELEEKIRKKEEEAKALPAAETEKVAVPVPVQEVEIDAAADLSGPQEVEKEEPPGSQDPEHTVTHGLEKAEAPGTVSSAAEGPKDPPVLPRIQEQFQKNPDSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQVSVALSSGTIRVAMVEENGERVLMEGKLTHKINTESSLWSLEPGRCVLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF", "length": 363 }, "evidence": [ { "id": "A0A8V0Z8F9", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to pericentriolar material", "id": "GO:1905793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F9" }, { "id": "PS51203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CS", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 291, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAB8-1", "uniprot_ac": "A0A8V0ZAB8", "uniprot_id": "A0A8V0ZAB8_CHICK", "mass": { "chemical_mass": 40073.0, "monoisotopic_mass": 40073.0 }, "refseq": { "ac": "XP_046787462", "name": "cytosolic acyl coenzyme A thioester hydrolase isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046787462" }, "gene_names": [ { "name": "ACOT7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ] }, { "name": "ACOT7", "type": "synonym", "evidence": [ { "id": "XP_046787462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046787462" } ] } ], "protein_names": [ { "name": "palmitoyl-CoA hydrolase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8/entry#names_and_taxonomy" } ] }, { "name": "cytosolic acyl coenzyme A thioester hydrolase isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046787462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046787462" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052593.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046787462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046787462" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACOT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8", "locus": { "chromosome": "21", "start_pos": 617314, "end_pos": 609953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019141", "url": "https://www.ensembl.org/id/ENSGALG00010019141" } ] } } ], "crossref": [ { "id": "A0A8V0ZAB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000652", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419371", "url": "https://www.ncbi.nlm.nih.gov/gene/419371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RTQ9", "url": "https://www.orthodb.org/?gene=A0A1L1RTQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2X9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZAB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11049", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11049", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11049:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11049:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046787462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046787462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RTQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RTQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RTQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLPAAGQRGRSACFWDREHRRSVSTSTWRIMRPDDANIAGNVHGGTVLKMIEEAGAIISTRHCNSGQGEPCVAALARVERTDFLSPMCIGEVANVSAEITYTSKHSVEVQVNVMSENILTGAKKVTNKATLWYVPLSLKNVNKVVEVPPIQYVHKEQEDEGRKRYEEQKLDRLETKQRNGDVILPVINPDRQTKEPHTVGYSQSSLIHLVGPSDCTLLGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHEKIKKGSVITISGRMTFTSNKSMEIEVFVDADPFVDEPQERYRAVSAFFTYVSLSKEGKPLPVPQLLTESEEEKRRFEEGKGRYLQTKAKRQAQLQQAAQH", "length": 359, "header": "tr|A0A8V0ZAB8-1|A0A8V0ZAB8_CHICK Isoform 1 of palmitoyl-CoA hydrolase OS=Gallus gallus OX=9031 GN=ACOT7 PE=1 SV=1 CANONICAL=A0A8V0ZAB8-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8/entry#A0A1L1RTQ9-1", "sequence": { "sequence": "MRLPAAGQRGRSACFWDREHRRSVSTSTWRIMRPDDANIAGNVHGGTVLKMIEEAGAIISTRHCNSGQGEPCVAALARVERTDFLSPMCIGEVANVSAEITYTSKHSVEVQVNVMSENILTGAKKVTNKATLWYVPLSLKNVNKVVEVPPIQYVHKEQEDEGRKRYEEQKLDRLETKQRNGDVILPVINPEPHTVGYSQSSLIHLVGPSDCTLLGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHEKIKKGSVITISGRMTFTSNKSMEIEVFVDADPFVDEPQERYRAVSAFFTYVSLSKEGKPLPVPQLLTESEEEKRRFEEGKGRYLQTKAKRQAQLQQAAQH", "length": 354, "header": "tr|A0A1L1RTQ9-1|A0A8V0ZAB8_CHICK Computationally mapped isoform of palmitoyl-CoA hydrolase OS=Gallus gallus OX=9031 GN=ACOT7 PE=1 SV=2 CANONICAL=A0A8V0ZAB8-1" }, "locus": { "chromosome": "21", "start_pos": 616774, "end_pos": 610033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046333.1", "url": "https://www.ensembl.org/id/ENSGALT00010046333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027596.1", "url": "https://www.ensembl.org/id/ENSGALP00010027596.1" } ] } }, { "isoform_ac": "A0A8V0Z2X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8/entry#A0A8V0Z2X9-1", "sequence": { "sequence": "MSERGAAGPGPATIQVSRIMRPDDANIAGNVHGGTVLKMIEEAGAIISTRHCNSGQGEPCVAALARVERTDFLSPMCIGEVANVSAEITYTSKHSVEVQVNVMSENILTGAKKVTNKATLWYVPLSLKNVNKVVEVPPIQYVHKEQEDEGRKRYEEQKLDRLETKQRNGDVILPVINPDRQTKEPHTVGYSQSSLIHLVGPSDCTLLGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHEKIKKGSVITISGRMTFTSNKSMEIEVFVDADPFVDEPQERYRAVSAFFTYVSLSKEGKPLPVPQLLTESEEEKRRFEEGKGRYLQTKAKRQAQLQQAAQH", "length": 347, "header": "tr|A0A8V0Z2X9-1|A0A8V0Z2X9_CHICK Computationally mapped isoform of palmitoyl-CoA hydrolase OS=Gallus gallus OX=9031 GN=ACOT7 PE=1 SV=1 CANONICAL=A0A8V0ZAB8-1" }, "locus": { "chromosome": "21", "start_pos": 616774, "end_pos": 610670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046315.1", "url": "https://www.ensembl.org/id/ENSGALT00010046315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027583.1", "url": "https://www.ensembl.org/id/ENSGALP00010027583.1" } ] } }, { "isoform_ac": "A0A8V0ZAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8/entry#A0A8V0ZAB8-1", "sequence": { "sequence": "MRLPAAGQRGRSACFWDREHRRSVSTSTWRIMRPDDANIAGNVHGGTVLKMIEEAGAIISTRHCNSGQGEPCVAALARVERTDFLSPMCIGEVANVSAEITYTSKHSVEVQVNVMSENILTGAKKVTNKATLWYVPLSLKNVNKVVEVPPIQYVHKEQEDEGRKRYEEQKLDRLETKQRNGDVILPVINPDRQTKEPHTVGYSQSSLIHLVGPSDCTLLGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHEKIKKGSVITISGRMTFTSNKSMEIEVFVDADPFVDEPQERYRAVSAFFTYVSLSKEGKPLPVPQLLTESEEEKRRFEEGKGRYLQTKAKRQAQLQQAAQH", "length": 359, "header": "tr|A0A8V0ZAB8-1|A0A8V0ZAB8_CHICK Isoform 1 of palmitoyl-CoA hydrolase OS=Gallus gallus OX=9031 GN=ACOT7 PE=1 SV=1 CANONICAL=A0A8V0ZAB8-1" }, "locus": { "chromosome": "21", "start_pos": 616774, "end_pos": 610033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046325.1", "url": "https://www.ensembl.org/id/ENSGALT00010046325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027591.1", "url": "https://www.ensembl.org/id/ENSGALP00010027591.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "medium-chain fatty-acyl-CoA catabolic process", "id": "GO:0036114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036114", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA catabolic process", "id": "GO:0036116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "medium-chain fatty acid biosynthetic process", "id": "GO:0051792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "palmitic acid biosynthetic process", "id": "GO:1900535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA binding", "id": "GO:0036042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NDD5-1", "A0A8V1A396-1", "A0A8V0ZAB8-1" ], "evidence": [ { "id": "R-GGA-5690043", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5690043" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZAB8", "gene_name": "ACOT7", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" } ] } ] }, { "uniprot_ac": "A0A8V1A396", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V1A396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A396" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V1A396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A396" } ] } ] }, { "uniprot_ac": "F1NDD5", "gene_name": "ACOT12", "activity": [ { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F1NDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDD5" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F1NDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDD5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB8" }, { "id": "PS51770", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HotDog ACOT-type", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 140, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.2", "ec_name": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "3.1.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2" }, { "id": "3.1.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9L6-1", "uniprot_ac": "A0A8V0Z9L6", "uniprot_id": "A0A8V0Z9L6_CHICK", "mass": { "chemical_mass": 77147.0, "monoisotopic_mass": 77147.0 }, "refseq": {}, "gene_names": [ { "name": "ANGEL2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ] } ], "protein_names": [ { "name": "Angel homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANGEL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6", "locus": { "chromosome": "3", "start_pos": 21431538, "end_pos": 21416028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019183", "url": "https://www.ensembl.org/id/ENSGALG00010019183" } ] } } ], "crossref": [ { "id": "A0A8V0Z9L6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009802", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009802", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421363", "url": "https://www.ncbi.nlm.nih.gov/gene/421363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421363", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRPPQFC", "url": "https://omabrowser.org/oma/group/WRPPQFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RUP1", "url": "https://www.orthodb.org/?gene=A0A1L1RUP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9L6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RUP1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RUP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHLPPARIPHIKAGGPQPRWRLRPHPSLAQHGGPASARAPPEPRWRRDAGRPLDYKSHGRAGERAWPSHRPRGVSGGQGVWRRQAELALPWNDPFWGRQVLAEQLAGPRGAGPGPGLAGRRPMLPRHVQRLGRDWITHVNGSQVFAFSSPVPTCMRWAGHCPWAPFPLPVPVDFSANWRLPLFFGPWRQFQNSNWQLDNFAQNSCIHLPNPSMKAEGEEPVTKKRRLSAQPDSPAPEEVNFSEQKEALCVSVSQDEKSESNKKVNIKRHWEYFCQHSRTMKILESTETDQSNRECEARFDFTVMSYNILSQNLLEDNSHLYKHCRQRLLIWTYRFPNILQEIKQLDADVLCLQEVQEDHYRKEIKSSLESLGYHCEYKMRTGRKSDGCAICFKTSKFSLISSNPVEFFRRDIPLLDRDNVGLVLLLQPKFPCKTNAAICIANTHLLYNPRRGDIKLTQLAMLLAEIASVAPQKNGSFCPIVMCGDFNSVPGSPLYRFIKEGKLNYEGLAIGKVSGQEQFPRGQRILSIPIWPKKLGISQNCVYEIKQQQKEDDAGEKTEGATSDNTKEIVIASEKLSSKLQHHFKLSSVYSHYFPETGLPEVTTCHSRSAVTVDYIFYSAANDDSVAQPGMEDSLHGGLKLLGRLALLTEKDLWTVNGLPNENNSSDHLPLLAEFRLIER", "length": 681, "header": "tr|A0A8V0Z9L6-1|A0A8V0Z9L6_CHICK Isoform 1 of Angel homolog 2 OS=Gallus gallus OX=9031 GN=ANGEL2 PE=4 SV=1 CANONICAL=A0A8V0Z9L6-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6/entry#A0A1L1RUP1-1", "sequence": { "sequence": "MLPRHVQRLGRDWITHVNGSQVFAFSSPVPTCMRWAGHCPWAPFPLPVPVDFSANWRLPLFFGPWRQFQNSNWQLDNFAQNSCIHLPNPSMKAEGEEPVTKKRRLSAQPDSPAPEEVNFSEQKEALCVSVSQDEKSESNKKVNIKRHWEYFCQHSRTMKILESTETDQSNRECEARFDFTVMSYNILSQNLLEDNSHLYKHCRQRLLIWTYRFPNILQEIKQLDADVLCLQEVQEDHYRKEIKSSLESLGYHCEYKMRTGRKSDGCAICFKTSKFSLISSNPVEFFRRDIPLLDRDNVGLVLLLQPKFPCKTNAAICIANTHLLYNPRRGDIKLTQLAMLLAEIASVAPQKNGSFCPIVMCGDFNSVPGSPLYRFIKEGKLNYEGLAIGKVSGQEQFPRGQRILSIPIWPKKLGISQNCVYEIKQQQKEDDAGEKTEGATSDNTKEIVIASEKLSSKLQHHFKLSSVYSHYFPETGLPEVTTCHSRSAVTVDYIFYSAANDDSVAQPGMEDSLHGGLKLLGRLALLTEKDLWTVNGLPNENNSSDHLPLLAEFRLIER", "length": 558, "header": "tr|A0A1L1RUP1-1|A0A8V0Z9L6_CHICK Computationally mapped isoform of Angel homolog 2 OS=Gallus gallus OX=9031 GN=ANGEL2 PE=4 SV=2 CANONICAL=A0A8V0Z9L6-1" }, "locus": { "chromosome": "3", "start_pos": 21431148, "end_pos": 21420488, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046398.1", "url": "https://www.ensembl.org/id/ENSGALT00010046398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027626.1", "url": "https://www.ensembl.org/id/ENSGALP00010027626.1" } ] } }, { "isoform_ac": "A0A8V0Z9L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6/entry#A0A8V0Z9L6-1", "sequence": { "sequence": "MHHLPPARIPHIKAGGPQPRWRLRPHPSLAQHGGPASARAPPEPRWRRDAGRPLDYKSHGRAGERAWPSHRPRGVSGGQGVWRRQAELALPWNDPFWGRQVLAEQLAGPRGAGPGPGLAGRRPMLPRHVQRLGRDWITHVNGSQVFAFSSPVPTCMRWAGHCPWAPFPLPVPVDFSANWRLPLFFGPWRQFQNSNWQLDNFAQNSCIHLPNPSMKAEGEEPVTKKRRLSAQPDSPAPEEVNFSEQKEALCVSVSQDEKSESNKKVNIKRHWEYFCQHSRTMKILESTETDQSNRECEARFDFTVMSYNILSQNLLEDNSHLYKHCRQRLLIWTYRFPNILQEIKQLDADVLCLQEVQEDHYRKEIKSSLESLGYHCEYKMRTGRKSDGCAICFKTSKFSLISSNPVEFFRRDIPLLDRDNVGLVLLLQPKFPCKTNAAICIANTHLLYNPRRGDIKLTQLAMLLAEIASVAPQKNGSFCPIVMCGDFNSVPGSPLYRFIKEGKLNYEGLAIGKVSGQEQFPRGQRILSIPIWPKKLGISQNCVYEIKQQQKEDDAGEKTEGATSDNTKEIVIASEKLSSKLQHHFKLSSVYSHYFPETGLPEVTTCHSRSAVTVDYIFYSAANDDSVAQPGMEDSLHGGLKLLGRLALLTEKDLWTVNGLPNENNSSDHLPLLAEFRLIER", "length": 681, "header": "tr|A0A8V0Z9L6-1|A0A8V0Z9L6_CHICK Isoform 1 of Angel homolog 2 OS=Gallus gallus OX=9031 GN=ANGEL2 PE=4 SV=1 CANONICAL=A0A8V0Z9L6-1" }, "locus": { "chromosome": "3", "start_pos": 21431148, "end_pos": 21419264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046403.1", "url": "https://www.ensembl.org/id/ENSGALT00010046403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027627.1", "url": "https://www.ensembl.org/id/ENSGALP00010027627.1" } ] } }, { "isoform_ac": "A0A8V0ZAE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6/entry#A0A8V0ZAE4-1", "sequence": { "sequence": "MAFVSFSLFSITGSVPEVSLYAPCCPAMCRGWAETGSPTSTVLSMKAEGEEPVTKKRRLSAQPDSPAPEEVNFSEQKEALCVSVSQDEKSESNKKVNIKRHWEYFCQHSRTMKILESTETDQSNRECEARFDFTVMSYNILSQNLLEDNSHLYKHCRQRLLIWTYRFPNILQEIKQLDADVLCLQEVQEDHYRKEIKSSLESLGYHCEYKMRTGRKSDGCAICFKTSKFSLISSNPVEFFRRDIPLLDRDNVGLVLLLQPKFPCKTNAAICIANTHLLYNPRRGDIKLTQLAMLLAEIASVAPQKNGSFCPIVMCGDFNSVPGSPLYRFIKEGKLNYEGLAIGKVSGQEQFPRGQRILSIPIWPKKLGISQNCVYEIKQQQKEDDAGEKTEGATSDNTKEIVIASEKLSSKLQHHFKLSSVYSHYFPETGLPEVTTCHSRSAVTVDYIFYSAANDDSVAQPGMEDSLHGGLKLLGRLALLTEKDLWTVNGLPNENNSSDHLPLLAEFRLIER", "length": 512, "header": "tr|A0A8V0ZAE4-1|A0A8V0ZAE4_CHICK Computationally mapped isoform of Angel homolog 2 OS=Gallus gallus OX=9031 GN=ANGEL2 PE=4 SV=1 CANONICAL=A0A8V0Z9L6-1" }, "locus": { "chromosome": "3", "start_pos": 21431148, "end_pos": 21420148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046383.1", "url": "https://www.ensembl.org/id/ENSGALT00010046383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027616.1", "url": "https://www.ensembl.org/id/ENSGALP00010027616.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2R2-1", "protein_name": "Angel homolog 2", "gene_name": "ANGEL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAWRCVRRGYGRCVVGRGRYPMLPHHQKSLGRDWTTPWENLQRCCWNRHISSCMRWPGHYSRAPYPYFSSRHFSLNWKPPCLFESRTQFQSWNWRPDNLSQTSLIHLSSYIMNSEGDEPSSKRRKHQGTIKRHWEYMCNHNKEKTKILGEKNGDPVCDNSENKFDFSVMSYNILSQDLLEDNSHLYRHCRQPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLGYHCEYKMRTGKKPDGCAICFKHSKFSLLSVNPVEFFRPNVPLLDRDNVGLVLLLQPKSPSAASPAICVANTHLLYNPRRGDIKLTQLAMLLAEISSVAHQKDGSFCPIVICGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEVQQVPKVEKTGSDLTQTQVDKTEVLVTDEKLSSNLQHHFSLSSVYSHYFPETGIPEVTTCHSRSAITVDYIFYSAEKEGVAGQQGAGVALVGGLKLLARLSLLTEQDLWTVNGLPNENNSSDHLPLLAKFRLDL", "length": 544 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6H7I3-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL2", "gene_name": "ANGEL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAWRCVRRGYGRCVVGRGRYPMLPHHQKSLGRDWTTPWENLQKCCWNRHISSCMRWPGHYSRAPYPYFSSRHFSLNWRPPGLFESRAPFQYWNWRPDSLSQTSLFHLSSYIMNSEGDEPSSKRRKHQGTIQRHWEYICNHNKENTKILGDENVDPICEDSENKFEFSVMSYNILSQDLLEDNSHLYKHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLGYHCEYKMRTGRKPDGCAICFKHSKFSLLSVNPVEFYRRDVPLLDRDNVGLVLLLQPKIPSATSPAICVANTHLLYNPRRGDIKLTQLAMLLAEISSVAHQKDGRFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEVQQVPKVEKPDGDLTQPELDKTEVLVTAEKLSSNLQHHFSLSSVYSHYLPDTGIPEVTTCHSRSAVTVDYIFYSAEKEGVAEQPGAEVALVGGLKLLARLSLLTEQDLWTVNGLPNENNSSDHLPLLAKFRLEL", "length": 544 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LT13-1", "protein_name": "Angel homolog 2", "gene_name": "Angel2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METWRCVRRGYGRCVAGRGRYSMLPYPLKSLGRDWTTPWEDLQKYCWRRHISSCLRWPGHYSRAPYPYFSSRHFSLNCRPPFLFESGTQFQYYNWRPDQLSNTSLFHLSRYVMNSDRDEPSSKRRKHQGTIKRSWEYLCSHNKEKTKDLEDRNGDSTCEDCEDKFDFSVMSYNILSQELLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLGYHCEYKMKTGRKPDGCAICFKHSKFSLLSVNPVEFCRRDIPLLDRDNIGLVLLLQPKIPRAASPSICIANTHLLYNPRRGDIKLTQLAMLLAEISNVAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEAQQVPKVEKTDSDVTQAQQEKAEVPVPADKVSSHLQHGFSLSSVYSHYVPDTGVPEVTTCHSRSAITVDYIFYSAEKDDTARGPGAEVALVGGLKLLARLSLLTEQDLWTVNGLPNEHNSSDHLPLLAKFRLEL", "length": 544 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RGT6-1", "protein_name": "RNA 2',3'-cyclic phosphatase angel2", "gene_name": "angel2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRKGRHMPRHTNANYARPGVSPNHPMFGRYLSTVGFPPAQNVYNHWRHWYQPGHLWWTQPPQLQHPSSSFSTVRHPFNRPPRPPDPYQWSSWRQTGVLPHTRGLHLSAGLMESTDRPPPQKRRKSAEGEISQRSPQHSPPKGSRSPKGSPEWLRNVSSIEVANRTSAVPELKRHWEDLSHLCKAAPSVNRGKQKWPFDFSVMSYNILSQDLLCDNTYLYRHCNPPVLDWRNRFPNIIKELEQYSADIMCLQEVQEDHYKQQIKPSLESLGYHCEFKRRTGLKPDGCAVIFKRERFSLVSCHPVEYFRRGVPLMDRDNVGLIVLLRPIDPHVSLSNICVANTHLLYNPRRGDIKLAQLAMLLAEISRVSQLPDSSVCPVLLCGDFNSVPWSPLYRFIKDRRLDYDGMPIGKVSGQEETPRGQRILTVPIWPRSLGISQQCQYENQTRDSELRDLEQTERESFTEASIEHCLRLTSAYSHHLKESGQPEITTCHSRTAITVDYIFYSAALGDVMAQAEYSAPPERGLQLLGRLALVGEKELQKVNGLPNQHNSSDHLPLLTRFRLHPQADS", "length": 569 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5VTE6-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL2", "gene_name": "ANGEL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAWRCVRKGYGHCVVGRGRYPMFPHHSRSLGRDWTTPWENLQRCCWNRHISSCMRWPGHYSRAPYPYFSSRHFSLNWRPPCLFESRTQFQYCNWRPDNLSQTSLIHLSSYVMNAEGDEPSSKRRKHQGVIKRNWEYICSHDKEKTKILGDKNVDPKCEDSENKFDFSVMSYNILSQDLLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGAEIRPSLESLGYHCEYKMRTGRKPDGCAICFKHSKFSLLSVNPVEFFRPDISLLDRDNVGLVLLLQPKIPYAACPAICVANTHLLYNPRRGDIKLTQLAMLLAEISSVAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLPIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEVQQVPKVEKTDSDLTQTQLKQTEVLVTAEKLSSNLQHHFSLSSVYSHYFPDTGIPEVTTCHSRSAITVDYIFYSAEKEDVAGHPGAEVALVGGLKLLARLSLLTEQDLWTVNGLPNENNSSDHLPLLAKFRLEL", "length": 544 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1C0-1", "protein_name": "RNA 2',3'-cyclic phosphatase ANGEL2", "gene_name": "Angel2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METWRCVRRGYGRCVAGRGRYSMFPYPLKSLGRDWTTPWEDLQKYCWRRHISSCLRWPGHYSRAPYPYFSSRHFSLNCRPPFLFESGTQFQYYNWRSDHLSNASLIHLSRHVMTSDRDEPLSKRRKHQGTIKRNWEYLCSHNKENTKDLEDRNVDSTCEDREDKFDFSVMSYNILSQDLLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLGYHCEYKMKTGRKPDGCAICFKHSRFSLLSVNPVEFCRRDIPLLDRDNIGLVLLLQPKIPRAASPSICIANTHLLYNPRRGDIKLTQLAMLLAEIANVTHRKDGSSCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEAQQVPKVEKTDSDVTQAQQEKAEVPVSADKVSSHLQHGFSLSSVYSHYVPDTGVPEVTTCHSRSAITVDYIFYTAKKENTAQGPGAEVALVGGLKLLARLSLLTEQDLWTVNGLPNEHNSSDHLPLLAKFRLEL", "length": 544 }, "evidence": [ { "id": "A0A8V0Z9L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "RNA 2'-phosphatase activity", "id": "GO:0160273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "RNA 2',3'-cyclic phosphatase activity", "id": "GO:0160272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160272", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA stabilization", "id": "GO:0070935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "negative regulation of RNA splicing", "id": "GO:0033119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "mitochondrial mRNA 3'-end processing", "id": "GO:0090616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" }, { "name": "negative regulation of tRNA processing", "id": "GO:2000236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 621, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L6" }, { "id": "PF19339", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein angel homolog 2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 294, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7Z6-1", "uniprot_ac": "A0A8V0Z7Z6", "uniprot_id": "A0A8V0Z7Z6_CHICK", "mass": { "chemical_mass": 68295.0, "monoisotopic_mass": 68295.0 }, "refseq": {}, "gene_names": [ { "name": "ARID5A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6" } ] } ], "protein_names": [ { "name": "AT-rich interaction domain 5A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARID5A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6", "locus": { "chromosome": "22", "start_pos": 3038736, "end_pos": 3043242, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020597", "url": "https://www.ensembl.org/id/ENSGALG00010020597" } ] } } ], "crossref": [ { "id": "A0A8V0Z7Z6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7Z6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039206", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16884", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101749459", "url": "https://www.ncbi.nlm.nih.gov/gene/101749459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DQMVPGK", "url": "https://omabrowser.org/oma/group/DQMVPGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3S0", "url": "https://www.orthodb.org/?gene=A0A3Q2U3S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7Z6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z802", "url": "https://www.orthodb.org/?gene=A0A8V0Z802", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13964:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13964:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U3S0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z802", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z802", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z802-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z802-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGELHKCLQGGGRRGRRGEGCALPQFPFWVLLSAPPLGPPPPPDGCIPPQESPSPEQAKPADASGEKEEEEAFLVSLYKFMKERHTPIERIPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKVSKGTETGEKSRRSKKEKGREQVAPEKAKPEVAATPGASKEEPAEAQEQGQPAEGCASPTAPAPSPSSGCPSTCRAHAEAYKRLFSSFYSKGNHPIMSPLAKKKLLAQVSKAESLHCLKRHCLEGREVASSAHPNPEPSRPAVSPHLKEQRSPETQGLKDTPRGGQSEAGPIPSTSPGRTDRQPYPRAEDGGPAPAVFTGFFHAYRNEVLKPISCHPFGGYFSNLKDFLEPQPEDTEAGREQPQDLRSKAWSRESPQPAAFAAIKACWVPPRAGFAPLPQSPTPPTAKRSRDEEALGPSRKLQVVSPFLHETEGRDKGAGSPRGHQGLAKPKAIIPGPGYAAPLTPVPQTPDVYKGAMLRFPVNFSNPLEHLKNQAAPPVPSLSINPFIIPAFPSPVVATSVQPSDPRHYPTSYEGSLQHRLYPTATWHSQHTYSTPHTSAFHRNTKL", "length": 625, "header": "tr|A0A8V0Z7Z6-1|A0A8V0Z7Z6_CHICK Isoform 1 of AT-rich interaction domain 5A OS=Gallus gallus OX=9031 GN=ARID5A PE=4 SV=1 CANONICAL=A0A8V0Z7Z6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6/entry#A0A3Q2U3S0-1", "sequence": { "sequence": "MEDGQEQHGGGEEPPASTEPTESPSPEQAKPADASGEKEEEEAFLVSLYKFMKERHTPIERIPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKVSKGTETGEKSRRSKKEKGREQVAPEKAKPEVAATPGASKEEPAEAQEQGQPAEGCASPTAPAPSPSSGCPSTCRAHAEAYKRLFSSFYSKGNHPIMSPLAKKKLLAQVSKAESLHCLKRHCLEGREVASSAHPNPEPSRPAVSPHLKEQRSPETQGLKDTPRGGQSEAGPIPSTSPGRTDRQPYPRAEDGGPAPAVFTGFFHAYRNEVLKPISCHPFGGYFSNLKDFLEPQPEDTEAGREQPQDLRSKAWSRESPQPAAFAAIKACWVPPRAGFAPLPQSPTPPTAKRSRDEEALGPSRKLQVVSPFLHETEGRDKGAGSPRGHQGLAKPKAIIPGPGYAAPLTPVPQTPDVYKGAMLRFPVNFSNPLEHLKNQAAPPVPSLSINPFIIPAFPSPVVATSVQPSDPRHYPTSYEGSLQHRLYPTATWHSQHTYSTPHTSAFHRNTKL", "length": 595, "header": "tr|A0A3Q2U3S0-1|A0A8V0Z7Z6_CHICK Computationally mapped isoform of AT-rich interaction domain 5A OS=Gallus gallus OX=9031 GN=ARID5A PE=4 SV=1 CANONICAL=A0A8V0Z7Z6-1" }, "locus": { "chromosome": "22", "start_pos": 3042795, "end_pos": 3039740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049709.1", "url": "https://www.ensembl.org/id/ENSGALT00010049709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029372.1", "url": "https://www.ensembl.org/id/ENSGALP00010029372.1" } ] } }, { "isoform_ac": "A0A8V0Z7Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6/entry#A0A8V0Z7Z6-1", "sequence": { "sequence": "MKGELHKCLQGGGRRGRRGEGCALPQFPFWVLLSAPPLGPPPPPDGCIPPQESPSPEQAKPADASGEKEEEEAFLVSLYKFMKERHTPIERIPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKVSKGTETGEKSRRSKKEKGREQVAPEKAKPEVAATPGASKEEPAEAQEQGQPAEGCASPTAPAPSPSSGCPSTCRAHAEAYKRLFSSFYSKGNHPIMSPLAKKKLLAQVSKAESLHCLKRHCLEGREVASSAHPNPEPSRPAVSPHLKEQRSPETQGLKDTPRGGQSEAGPIPSTSPGRTDRQPYPRAEDGGPAPAVFTGFFHAYRNEVLKPISCHPFGGYFSNLKDFLEPQPEDTEAGREQPQDLRSKAWSRESPQPAAFAAIKACWVPPRAGFAPLPQSPTPPTAKRSRDEEALGPSRKLQVVSPFLHETEGRDKGAGSPRGHQGLAKPKAIIPGPGYAAPLTPVPQTPDVYKGAMLRFPVNFSNPLEHLKNQAAPPVPSLSINPFIIPAFPSPVVATSVQPSDPRHYPTSYEGSLQHRLYPTATWHSQHTYSTPHTSAFHRNTKL", "length": 625, "header": "tr|A0A8V0Z7Z6-1|A0A8V0Z7Z6_CHICK Isoform 1 of AT-rich interaction domain 5A OS=Gallus gallus OX=9031 GN=ARID5A PE=4 SV=1 CANONICAL=A0A8V0Z7Z6-1" }, "locus": { "chromosome": "22", "start_pos": 3042099, "end_pos": 3039740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049700.1", "url": "https://www.ensembl.org/id/ENSGALT00010049700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029364.1", "url": "https://www.ensembl.org/id/ENSGALP00010029364.1" } ] } }, { "isoform_ac": "A0A8V0Z802-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z6/entry#A0A8V0Z802-1", "sequence": { "sequence": "MCPFFSTRRARPKGVGRGETRMEDGQEQHGGGEEPPASTEPTESPSPEQAKPADASGEKEEEEAFLVSLYKFMKERHTPIERIPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKVSKGTETGEKSRRSKKEKGREQVAPEKAKPEVAATPGASKEEPAEAQEQGQPAEGCASPTAPAPSPSSGCPSTCRAHAEAYKRLFSSFYSKGNHPIMSPLAKKKLLAQVSKAESLHCLKRHCLEGREVASSAHPNPEPSRPAVSPHLKEQRSPETQGLKDTPRGGQSEAGPIPSTSPGRTDRQPYPRAEDGGPAPAVFTGFFHAYRNEVLKPISCHPFGGYFSNLKDFLEPQPEDTEAGREQPQDLRSKAWSRESPQPAAFAAIKACWVPPRAGFAPLPQSPTPPTAKRSRDEEALGPSRKLQVVSPFLHETEGRDKGAGSPRGHQGLAKPKAIIPGPGYAAPLTPVPQTPDVYKGAMLRFPVNFSNPLEHLKNQAAPPVPSLSINPFIIPAFPSPVVATSVQPSDPRHYPTSYEGSLQHRLYPTATWHSQHTYSTPHTSAFHRNTKL", "length": 616, "header": "tr|A0A8V0Z802-1|A0A8V0Z802_CHICK Computationally mapped isoform of AT-rich interaction domain 5A OS=Gallus gallus OX=9031 GN=ARID5A PE=4 SV=1 CANONICAL=A0A8V0Z7Z6-1" }, "locus": { "chromosome": "22", "start_pos": 3042858, "end_pos": 3039740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049706.1", "url": "https://www.ensembl.org/id/ENSGALT00010049706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029369.1", "url": "https://www.ensembl.org/id/ENSGALP00010029369.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 460, "start_aa": "Thr", "end_pos": 460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr460", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B8I4-1", "protein_name": "AT-rich interaction domain 5A", "gene_name": "ARID5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPPVKGKRKQSEGSDPLDPPVSPQPDGGQSRSQSPVQLEDPPEAGGEREEEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPSKPRKQYKMAKEAQGDDGATERQKKAKEEKQVDQMTPGKTKTDAPDLARLPSQEPPRDSMEQPGPAPGPSLPFVGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKAEALQCQEGGCRHGASGEPQVPSTVQPLESPQSPGGLAENSRHQLTPPEGVQGPGGSLREEAQVGPRPSAPTFTGCLHTYSSEVLKPISQHPRDFLPSLKDAVLLGPPGKEEGLPTKEPQLVWGGDANRPSAFHKGGSRKGSLYPKPKACWVSPMTKVPAESPVPTFPSSPGLGSKRSLEEEGLVHGGKKLRAVSPFLKEVDAKECGTKSVGPGLAVSCLLGPALGPTFPEAYRGTMLRCPLNFTGTPDPLKGQAPLPFSPLVIPAFPAHLLATTAPSPMAAGLMHFPPASFDSALRHRLCPASSAWHVPPATTYAAPHFSFHLNTKL", "length": 597 }, "evidence": [ { "id": "A0A8V0Z7Z6", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q03989-1", "protein_name": "AT-rich interactive domain-containing protein 5A", "gene_name": "ARID5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPVKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPEAGGEREEEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAKEERRMDQMMPGKTKADAADPAPLPSQEPPRNSTEQQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPCPAAPIFKGCFYTHPTEVLKPVSQHPRDFFSRLKDGVLLGPPGKEGLSVKEPQLVWGGDANRPSAFHKGGSRKGILYPKPKACWVSPMAKVPAESPTLPPTFPSSPGLGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGLVSCLLGPALGPVPPEAYRGTMLHCPLNFTGTPGPLKGQAALPFSPLVIPAFPAHFLATAGPSPMAAGLMHFPPTSFDSALRHRLCPASSAWHAPPVTTYAAPHFFHLNTKL", "length": 594 }, "evidence": [ { "id": "A0A8V0Z7Z6", "url": "https://omabrowser.org/oma/group/A0A8V0Z7Z6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U108-1", "protein_name": "AT-rich interactive domain-containing protein 5A", "gene_name": "Arid5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61", "locus": { "chromosome": "14", "start_pos": 3085967, "end_pos": 3109253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019962", "url": "https://www.ensembl.org/id/ENSGALG00010019962" } ] } } ], "crossref": [ { "id": "A0A8V0ZB61", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB61", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004255", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004255", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07597", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07597", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416468", "url": "https://www.ncbi.nlm.nih.gov/gene/416468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WEYAGAK", "url": "https://omabrowser.org/oma/group/WEYAGAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5T3", "url": "https://www.orthodb.org/?gene=A0A3Q2U5T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5D1", "url": "https://www.orthodb.org/?gene=A0A8V0Z5D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB61", "url": "https://www.orthodb.org/?gene=A0A8V0ZB61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCL4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIM9", "url": "https://www.orthodb.org/?gene=A0A8V0ZIM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46571:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46571:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U5T3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLWRSWRRSRVRKSIRYFGIFPSRADVRYWDIEQQPLWKKCPTVSKRELPQTDLFREEAAHLFHAGEQKPDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 500, "header": "tr|A0A8V0ZB61-1|A0A8V0ZB61_CHICK Isoform 1 of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U5T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A3Q2U5T3-1", "sequence": { "sequence": "MSYCVKERAPSDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 440, "header": "tr|A0A3Q2U5T3-1|A0A8V0ZB61_CHICK Computationally mapped isoform of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3108260, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048217.1", "url": "https://www.ensembl.org/id/ENSGALT00010048217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028433.1", "url": "https://www.ensembl.org/id/ENSGALP00010028433.1" } ] } }, { "isoform_ac": "A0A8V0Z5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A8V0Z5D1-1", "sequence": { "sequence": "MTAVAMDGDPPAGSAGVGTDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 448, "header": "tr|A0A8V0Z5D1-1|A0A8V0ZB61_CHICK Computationally mapped isoform of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3109194, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048232.1", "url": "https://www.ensembl.org/id/ENSGALT00010048232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028441.1", "url": "https://www.ensembl.org/id/ENSGALP00010028441.1" } ] } }, { "isoform_ac": "A0A8V0ZB61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A8V0ZB61-1", "sequence": { "sequence": "MGLWRSWRRSRVRKSIRYFGIFPSRADVRYWDIEQQPLWKKCPTVSKRELPQTDLFREEAAHLFHAGEQKPDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 500, "header": "tr|A0A8V0ZB61-1|A0A8V0ZB61_CHICK Isoform 1 of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3108382, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048206.1", "url": "https://www.ensembl.org/id/ENSGALT00010048206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028427.1", "url": "https://www.ensembl.org/id/ENSGALP00010028427.1" } ] } }, { "isoform_ac": "A0A8V0ZCL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A8V0ZCL4-1", "sequence": { "sequence": "MEEQTDLFREEAAHLFHAGEQKPDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 452, "header": "tr|A0A8V0ZCL4-1|A0A8V0ZCL4_CHICK Computationally mapped isoform of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3103203, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048199.1", "url": "https://www.ensembl.org/id/ENSGALT00010048199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028423.1", "url": "https://www.ensembl.org/id/ENSGALP00010028423.1" } ] } }, { "isoform_ac": "A0A8V0ZIM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A8V0ZIM9-1", "sequence": { "sequence": "MTGSWEMPERGAVFTARRFSGALLERRPFPSGTCRALSAFRFCPLEGGLTDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 479, "header": "tr|A0A8V0ZIM9-1|A0A8V0ZIM9_CHICK Computationally mapped isoform of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3108605, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048212.1", "url": "https://www.ensembl.org/id/ENSGALT00010048212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028431.1", "url": "https://www.ensembl.org/id/ENSGALP00010028431.1" } ] } }, { "isoform_ac": "A0A8V0ZIN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61/entry#A0A8V0ZIN4-1", "sequence": { "sequence": "MSYCVKERAPSAFWFGIRDLGKPAPMLNFFREQQFVNFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLKQALKGLSVEFALLADKAVQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSMMKKQMMSATVQNKEPESVEQLESRIVEQENAILTMELRNYFSLYCLHQETQLIHIYLPLTSHILGAFVNSQIQGHKEMSKVWNELKPKLSCLFVGSSNMPTPPLSPPDGNFFSN", "length": 465, "header": "tr|A0A8V0ZIN4-1|A0A8V0ZIN4_CHICK Computationally mapped isoform of Sorting nexin-8 OS=Gallus gallus OX=9031 GN=SNX8 PE=1 SV=1 CANONICAL=A0A8V0ZB61-1" }, "locus": { "chromosome": "14", "start_pos": 3108260, "end_pos": 3092359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048224.1", "url": "https://www.ensembl.org/id/ENSGALT00010048224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028436.1", "url": "https://www.ensembl.org/id/ENSGALP00010028436.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480WKY2-1", "protein_name": "Sorting nexin-8", "gene_name": "SNX8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGAMDPLPAAPVAAAPEAEADEEADPPVADLPAPQVSEPTALDSSRMQMPPGNPLLLSLTLQELLARDAVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIEARRRALKRFINLVARHPPFSEDVVLKLFLSFSGPDVQNKLKESAQCVGDEFMNCKLAARAKDFLPADIQTQFAVSRELIRNIYNSFYKLRDRAERMVSRAIDNAADLLVFGKELSALGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLSLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAAVQNREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLQPKLHCLFAGPHGAPTPPRSPRDGPSPH", "length": 459 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZUJ9-1", "protein_name": "Sorting nexin-8", "gene_name": "Snx8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGRAMDPLPSPAVAAAAEAEADEEADPPATGPQTSQVTEWRNLDPRRMQMPQGNPLLLSYTLQELLAKDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLGADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFTNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELRQVTLALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADKAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAHGREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGMCPH", "length": 463 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6NGW9-1", "protein_name": "Sorting nexin-8a", "gene_name": "snx8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGDINEGSVPSYYREVHQALCSASDERVPVNVFQRVFTRTSLPITVQNQILEHVNSSDGFLSKVSLYKALALIALAQQGKPPSPKLLENFIQDFPKPQLGEPKELHSLKMQTVQDSPLILSLTLAELLKKDTIKIELTPEKKGLFLKHVEYQVTSERFTLTVYRRYSDFDVFHELLLQRYSYRVVPALPPKRALKGVLTSVSEREFIEGRRRALTRFLNLVARHPVFSEDELVKTFLTFSGSDVQSKLRDACRKLGDEFMTCKFATQAKDYLPADIQSQFSSSRQLIRNIHSSFQKLRDRAEKMAERSKDNATDLLMFGKELSFLGSDESPVPILVSGRNPWSALRHSVKGLSVDFSALSEKAARQGRREEDEVVEKLDMFLDLLQSYRDLCERHEKGVLHDHQRALQKYGIMKRQIMSATVQPKEQLSVEQLESRIVQQENAIQAMELRNYFSLFCLHQESQLIFTYLPITSHILASFVDSQVQGHKEMGEVWQDLHSKLKSLFGDGNGRSPPLSPK", "length": 519 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P40959-1", "protein_name": "Sorting nexin MVP1", "gene_name": "MVP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTLNFSTPLDTNEEDTGFLPTNDVLEESIWDDSRNPLGATGMSQTPNIAANETVIDKNDARDQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLLFKHANYLVKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVRTDLTSWRKQATYDTSNEFADKKISQEFMKMWKKEFAEQWNQAASCIDTSMELWYRITLLLERHEKRIMQMVHERNFFETLVDNFSEVTPKLYPVQQNDTILDINNNLSIIKKHLETTSSICKQETEEISGTLSPKFKIFTDILLSLRSLFERYKIMAANNVVELQRHVELNKEKLESMKGKPDVSGAEYDRIKKIIQKDRRSIIEQSNRAWLIRQCILEEFTIFQETQFLITRAFQDWAKLNSNHAGLKLNEWEKLVTSIMDMPISRE", "length": 511 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KHV6-1", "protein_name": "Sorting nexin-8", "gene_name": "SNX8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGGAMDPLPTAPGAAAAEAEVDEEADPPAADSPVPPVSEPRAPDAGQMQVPPGNPLLLSLTLQELLARDAVQVELVPEKKGLFLKHVEYEVSSQRFKSCVYRRYNDFVVFHETLLHKFPYRMVPALPPKRMLGADREFIEARRRALKRFINLVARHPPFSEDTILKLFLSFSGPDVQNKLKESAQCLGDEFMNCRLAARAKDFLPADIQTQFAMSRELIRNIYNSFHKLRDRAERMVSRAIDNAADLLIFGKELSALGSDTTPLPSWASLNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMVSAAVQSREPESMEQLESRIVQQENVIQTMELRSHFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLQPKLRCLFVGPHGAPAPPRPPQDGLSAH", "length": 459 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CFD4-1", "protein_name": "Sorting nexin-8", "gene_name": "Snx8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGRAMDPLPSPAVAAAAEAEADEEADPPATGPRTSQVTEWRALDPGRMQMPQGNPLLLSYTLQELLAKDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLGADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELSALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADRAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAHGREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGVCPH", "length": 459 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5X2-1", "protein_name": "Sorting nexin-8", "gene_name": "SNX8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH", "length": 465 }, "evidence": [ { "id": "A0A8V0ZB61", "url": "https://omabrowser.org/oma/group/A0A8V0ZB61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB61" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 216, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 487 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAH3-1", "uniprot_ac": "A0A8V0ZAH3", "uniprot_id": "A0A8V0ZAH3_CHICK", "mass": { "chemical_mass": 40091.0, "monoisotopic_mass": 40091.0 }, "refseq": {}, "gene_names": [ { "name": "RMND5A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ] } ], "protein_names": [ { "name": "Required for meiotic nuclear division 5 homolog A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RMND5A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3", "locus": { "chromosome": "4", "start_pos": 85165884, "end_pos": 85147341, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019218", "url": "https://www.ensembl.org/id/ENSGALG00010019218" } ] } } ], "crossref": [ { "id": "A0A8V0ZAH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015815", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015815", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422920", "url": "https://www.ncbi.nlm.nih.gov/gene/422920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UDK7", "url": "https://www.orthodb.org/?gene=A0A3Q2UDK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAH3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12170:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9861718", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9861718", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UDK7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UDK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UDK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UDK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVERGETCRGKADQDGDLSGTISLVMTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRILNEVMVEHFFRQGMLDVAEELCQESGLSIDQSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSLEFKLHRLYFISLLMGGTANQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 357, "header": "tr|A0A8V0ZAH3-1|A0A8V0ZAH3_CHICK Isoform 1 of Required for meiotic nuclear division 5 homolog A OS=Gallus gallus OX=9031 GN=RMND5A PE=4 SV=1 CANONICAL=A0A8V0ZAH3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UDK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3/entry#A0A3Q2UDK7-1", "sequence": { "sequence": "MNVERGETCRDQDGDLSGTISLVMTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRILNEVMVEHFFRQGMLDVAEELCQESGLSIDQSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSLEFKLHRLYFISLLMGGTANQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 354, "header": "tr|A0A3Q2UDK7-1|A0A8V0ZAH3_CHICK Computationally mapped isoform of Required for meiotic nuclear division 5 homolog A OS=Gallus gallus OX=9031 GN=RMND5A PE=4 SV=1 CANONICAL=A0A8V0ZAH3-1" }, "locus": { "chromosome": "4", "start_pos": 85164249, "end_pos": 85147609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046438.1", "url": "https://www.ensembl.org/id/ENSGALT00010046438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027646.1", "url": "https://www.ensembl.org/id/ENSGALP00010027646.1" } ] } }, { "isoform_ac": "A0A8V0ZAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3/entry#A0A8V0ZAH3-1", "sequence": { "sequence": "MNVERGETCRGKADQDGDLSGTISLVMTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRILNEVMVEHFFRQGMLDVAEELCQESGLSIDQSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSLEFKLHRLYFISLLMGGTANQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF", "length": 357, "header": "tr|A0A8V0ZAH3-1|A0A8V0ZAH3_CHICK Isoform 1 of Required for meiotic nuclear division 5 homolog A OS=Gallus gallus OX=9031 GN=RMND5A PE=4 SV=1 CANONICAL=A0A8V0ZAH3-1" }, "locus": { "chromosome": "4", "start_pos": 85164249, "end_pos": 85147609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046442.1", "url": "https://www.ensembl.org/id/ENSGALT00010046442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027649.1", "url": "https://www.ensembl.org/id/ENSGALP00010027649.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9861718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9861718", "resource": "Reactome", "description": "Regulation of pyruvate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" }, { "id": "PS50897", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTLH", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 176, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH3" }, { "id": "PS51867", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51867" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-Gid-type", "eco_id": "ECO_0000259", "start_pos": 302, "end_pos": 343, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB66-1", "uniprot_ac": "A0A8V0ZB66", "uniprot_id": "A0A8V0ZB66_CHICK", "mass": { "chemical_mass": 182760.0, "monoisotopic_mass": 182760.0 }, "refseq": {}, "gene_names": [ { "name": "CEP170B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66" } ] } ], "protein_names": [ { "name": "Centrosomal protein 170B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP170B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66", "locus": { "chromosome": "5", "start_pos": 51294003, "end_pos": 51240725, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019967", "url": "https://www.ensembl.org/id/ENSGALG00010019967" } ] } } ], "crossref": [ { "id": "cd22725", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22725", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5E4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB66", "url": "https://www.orthodb.org/?gene=A0A8V0ZB66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB81", "url": "https://www.orthodb.org/?gene=A0A8V0ZB81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC28", "url": "https://www.orthodb.org/?gene=A0A8V0ZC28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCN2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSGNEERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGSRSLTESSCVPSHPFPSPKKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTSRRRPQGSDYTSTSEEEYGSNHSSPKHKRSHTSTATQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREELVQHIPEASLNYQKVPPGSVELKSFDQNMNDNREDDLSKKTRTRNREEVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1658, "header": "tr|A0A8V0ZB66-1|A0A8V0ZB66_CHICK Isoform 1 of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#A0A8V0Z5E4-1", "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGSRSLTESSCVPSHPFPSPKKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTTQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREEIARRSFRLAYPSQLVQHIPEASLNYQKVPPGSVELKSFDQNMNDNREDDLSKKTRTRNREEVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1633, "header": "tr|A0A8V0Z5E4-1|A0A8V0ZB66_CHICK Computationally mapped isoform of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "locus": { "chromosome": "5", "start_pos": 51292097, "end_pos": 51242093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048253.1", "url": "https://www.ensembl.org/id/ENSGALT00010048253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028452.1", "url": "https://www.ensembl.org/id/ENSGALP00010028452.1" } ] } }, { "isoform_ac": "A0A8V0ZB66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#A0A8V0ZB66-1", "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSGNEERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGSRSLTESSCVPSHPFPSPKKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTSRRRPQGSDYTSTSEEEYGSNHSSPKHKRSHTSTATQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREELVQHIPEASLNYQKVPPGSVELKSFDQNMNDNREDDLSKKTRTRNREEVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1658, "header": "tr|A0A8V0ZB66-1|A0A8V0ZB66_CHICK Isoform 1 of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "locus": { "chromosome": "5", "start_pos": 51292097, "end_pos": 51242093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048216.1", "url": "https://www.ensembl.org/id/ENSGALT00010048216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028432.1", "url": "https://www.ensembl.org/id/ENSGALP00010028432.1" } ] } }, { "isoform_ac": "A0A8V0ZB81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#A0A8V0ZB81-1", "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTTQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREEIARRSFRLAYPSQLVQHIPEASLNYQKVPPGSVELKSFDQNMNDNREDDLSKKTRTRNREEVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1612, "header": "tr|A0A8V0ZB81-1|A0A8V0ZB81_CHICK Computationally mapped isoform of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "locus": { "chromosome": "5", "start_pos": 51292097, "end_pos": 51242093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048247.1", "url": "https://www.ensembl.org/id/ENSGALT00010048247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028449.1", "url": "https://www.ensembl.org/id/ENSGALP00010028449.1" } ] } }, { "isoform_ac": "A0A8V0ZC28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#A0A8V0ZC28-1", "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGSRSLTESSCVPSHPFPSPKKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTSRRRPQGSDYTSTSEEEYGSNHSSPKHKRSHTSTATQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREEIARRSFRLAYPSQVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1620, "header": "tr|A0A8V0ZC28-1|A0A8V0ZC28_CHICK Computationally mapped isoform of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "locus": { "chromosome": "5", "start_pos": 51292097, "end_pos": 51242093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048229.1", "url": "https://www.ensembl.org/id/ENSGALT00010048229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028440.1", "url": "https://www.ensembl.org/id/ENSGALP00010028440.1" } ] } }, { "isoform_ac": "A0A8V0ZCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66/entry#A0A8V0ZCN2-1", "sequence": { "sequence": "MSVTSWFLVSSTGIRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDKEKDEHWVKDLGSLNGTFVNDVRIPDQKYITLKLNDVIRFGYDSNMYVLEQIQHKVPEEALKHEKYTSQLQMNFKGTATKRVEQPMEHSVYTESPQAKLEKGERKPITETNSYRTPLYGQPSWWGEDDANNKEDRRQEEHYSERSKEMTQHDEELNGNISTYRDSQEQSVFAFRREPSYFEIPTKEFQQPSKSPETQVHEIPTKDIDAIVAPVVQSHASFTIEFDDGTPGKIKIKDHVTKFSLRQRRPYSKEPAHTEVMSAESKVADWLVQNDPSLIRRQSPGEDVYSTKSDLPVHVRTLKGSRSLTESSCVPSHPFPSPKKGNRHEDGTQSDSEDPVAPKAEKELTTGGERVTEQAKLQRQMRRDPHEMLHNKQAFVIEFFEDTPRKKRSQSFTHSAHSSQSDTDPGLKTKVEKRKNAVPTEKQGSTVPPSHVGTQGGKATNSSSGTQRASSFKREKTEERISSSSSSASRASGRAYGSVGRKSKMAQDFMAEYLRETAQSGKASSEKPAPQPVPAAPCVVISSEPEPASAPSPELKAAQGRRNDEEDSVSETGTYTIETESQDKEVEEARKMIDQVFGVLESPEFSRISSAFRPVIKGEKDDSGSHQHLVSENGTCQKSPLLQAFASKAVSGSQADMQMSAASQGSQKWVSRWASLADSYSDSGSVSGQADGAAESGVAPKSGEPENAVPLRTRRLLPQLPPSDKSESPTPTVLVCQESYSEVTKRTIVKDHCVETYSDHSSRLFIQEDLDPDSLSDASRSDDGFSSEKGKKYKENNKMLEQMGEDTKSESRQPGVPRVANVRAVSETVSTSFYIGDDSSDVGIPSKLSLSVAHARTDKDGKDQEFSFKSTGTPVPGKPLGKDVSAYINAAGKMVISVHQSPPDQESMAGKEISFVRQESFTKDKSSSAVPQNKLPHISSHPLLKDLEAVRSTRMDFGQDTHLLLKDTETALAVLEAKLLGQSQKLEPSEAAGQLEDSLSGDSDVDTASTVSLVSGKNVPASAPKRKAVASLQKEKSSSSPSIQDQCGQPSARDRLTEKRKANVPEAPRCVEATKRFQMKRSAGTRGSLDFTDDERSSSLPYLPVPDAVVSDHEHSVPRPAPRRKPFTQAAKEDHSKTTANVQKIQQVLTRSNSLSTPRPTRASKLRRARLGDASDNECVDTEKTASNPEAAAPGSKQSTETKKLSRLDILAMPRKRAGSFTVPSDSETAQSRTGFSGRSVESYRKATVSEIRAAARKTAAAASAKQPFSRTRSSSVKYSPSSTSRRRPQGSDYTSTSEEEYGSNHSSPKHKRSHTSTATQTPRIRGSGLGKQKHNGRETDDDEDFDDHPDPYNFMAQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSQSSSGTGPSTSLSSVPNTPASTISAREEVIFDNLMLNPVSQLSHTIRENTENLAEKMKILFQNSERTWEEMEAKINSENEVPILKTSNKEISSILKELRRVQKQLEVINAIIDPTGNLDVVASNKASSAAKQSTATKVRTANTSGSTLETLSPAQMRNYTQKSNCGSSSLQDTNFIPDGEKYVI", "length": 1607, "header": "tr|A0A8V0ZCN2-1|A0A8V0ZCN2_CHICK Computationally mapped isoform of Centrosomal protein 170B OS=Gallus gallus OX=9031 GN=CEP170B PE=3 SV=1 CANONICAL=A0A8V0ZB66-1" }, "locus": { "chromosome": "5", "start_pos": 51292097, "end_pos": 51242093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048238.1", "url": "https://www.ensembl.org/id/ENSGALT00010048238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028444.1", "url": "https://www.ensembl.org/id/ENSGALP00010028444.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 764, "start_aa": "Thr", "end_pos": 764, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr764", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1616, "end_pos": 1618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1632, "end_pos": 1634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB66" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 73, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 764 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1616, "end_pos": 1618 }, { "start_pos": 1632, "end_pos": 1634 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 667, "end_pos": 669 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ] } ], "protein_names": [ { "name": "Neuroendocrine convertase 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.94", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#names_and_taxonomy" } ] }, { "name": "Prohormone convertase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017927", "url": "https://www.ensembl.org/id/ENSGALG00010017927" } ] } } ], "crossref": [ { "id": "A0A8V0ZB97", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB97", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5E6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB97", "url": "https://www.orthodb.org/?gene=A0A8V0ZB97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGRGAMPAGPPPLLLRGAFVLLLLVLLLLSLGAPARAAVYTNQFLVELHSGDQAEAERVAADHGFGGVRKLPFLDTGYYFYHNGIAKARRRRSFQHKLHLEKDSRVKKAVQQEGFSRRKRGYRDINDIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAQASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQVIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSKRNQLHDEVHRWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSIQEPEKIPPSGKLVLTLTTDACEGKENFVRYLEHVQAVITVNSTRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDPRGTWVLEIGFVGGVPQRGVLKEWTLMLHGTQSAPYIDQIVKDYQSKLAMSKKEELEEELDEAVERSLKSILSKN", "length": 651, "header": "tr|A0A8V0ZB97-1|A0A8V0ZB97_CHICK Isoform 1 of Neuroendocrine convertase 2 OS=Gallus gallus OX=9031 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A8V0ZB97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#A0A8V0Z5E6-1", "sequence": { "sequence": "MNSVMCFLIGSLAVFPAIVPTLLQDFRYGVSFMTTGSCCPYSSQDLAVMLPFLDTGYYFYHNGIAKARRRRSFQHKLHLEKDSRVKKAVQQEGFSRRKRGYRDINDIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAQASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQVIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSKRNQLHDEVHRWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSIQEPEKIPPSGKLVLTLTTDACEGKENFVRYLEHVQAVITVNSTRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDPRGTWVLEIGFVGGVPQRGVLKEWTLMLHGTQSAPYIDQIVKDYQSKLAMSKKEELEEELDEAVERSLKSILSKN", "length": 628, "header": "tr|A0A8V0Z5E6-1|A0A8V0ZB97_CHICK Computationally mapped isoform of Neuroendocrine convertase 2 OS=Gallus gallus OX=9031 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A8V0ZB97-1" }, "locus": { "chromosome": "3", "start_pos": 11776538, "end_pos": 11685215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043341.1", "url": "https://www.ensembl.org/id/ENSGALT00010043341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025762.1", "url": "https://www.ensembl.org/id/ENSGALP00010025762.1" } ] } }, { "isoform_ac": "A0A8V0ZB97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97/entry#A0A8V0ZB97-1", "sequence": { "sequence": "MLSGRGAMPAGPPPLLLRGAFVLLLLVLLLLSLGAPARAAVYTNQFLVELHSGDQAEAERVAADHGFGGVRKLPFLDTGYYFYHNGIAKARRRRSFQHKLHLEKDSRVKKAVQQEGFSRRKRGYRDINDIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAQASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQVIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSKRNQLHDEVHRWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSIQEPEKIPPSGKLVLTLTTDACEGKENFVRYLEHVQAVITVNSTRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDPRGTWVLEIGFVGGVPQRGVLKEWTLMLHGTQSAPYIDQIVKDYQSKLAMSKKEELEEELDEAVERSLKSILSKN", "length": 651, "header": "tr|A0A8V0ZB97-1|A0A8V0ZB97_CHICK Isoform 1 of Neuroendocrine convertase 2 OS=Gallus gallus OX=9031 GN=PCSK2 PE=3 SV=1 CANONICAL=A0A8V0ZB97-1" }, "locus": { "chromosome": "3", "start_pos": 11779688, "end_pos": 11685215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043347.1", "url": "https://www.ensembl.org/id/ENSGALT00010043347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025765.1", "url": "https://www.ensembl.org/id/ENSGALP00010025765.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" }, { "name": "insulin processing", "id": "GO:0030070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB97" }, { "id": "PS51829", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P/Homo B", "eco_id": "ECO_0000259", "start_pos": 474, "end_pos": 610, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.94", "ec_name": "Release of protein hormones and neuropeptides from their precursors, generally by hydrolysis of -Lys-Arg-|- bonds.", "evidence": [ { "id": "3.4.21.94", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.94" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 388, "end_pos": 390 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBG5-1", "uniprot_ac": "A0A8V0ZBG5", "uniprot_id": "A0A8V0ZBG5_CHICK", "mass": { "chemical_mass": 123635.0, "monoisotopic_mass": 123635.0 }, "refseq": { "ac": "XP_046756183", "name": "TATA element modulatory factor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756183" }, "gene_names": [ { "name": "TMF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ] }, { "name": "TMF1", "type": "synonym", "evidence": [ { "id": "XP_046756183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756183" } ] } ], "protein_names": [ { "name": "TATA element modulatory factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5/entry#names_and_taxonomy" } ] }, { "name": "TATA element modulatory factor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046756183", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756183" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756183" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5", "locus": { "chromosome": "12", "start_pos": 15477831, "end_pos": 15491883, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020036", "url": "https://www.ensembl.org/id/ENSGALG00010020036" } ] } } ], "crossref": [ { "id": "A0A8V0ZBG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "426072", "url": "https://www.ncbi.nlm.nih.gov/gene/426072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426072", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426072", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEMHGYI", "url": "https://omabrowser.org/oma/group/EEMHGYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5M4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZBG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46515:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46515:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12329", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12329", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046756183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756183", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGIDGPGRPLHFWEPRTALLDASAEAEVVPHRHDRYRGGSGGGTPSAMTGTNSLISGGWDTSSWGLSSNTEPQNQPVSPTAITKPVRRAVVDESENFFSAFLSPTDVQSIQKSPVVSKPPAKSQRPKEEVKSTLKEPQHFSQLEVLVTTEAEVKDSSVGGLVDLKNRDSPKEKLGENSVLKSNAEHEESTNEVADKKASALNLKEPEDALNGKSNVGADRTGGALDSNSQPPNTGTKDAALETKEQKTEDRQSNTPSPPISTFSSGTSTTSDIEVLDHESVISESSVSSRQEAADSKSSLHLMQTSFQLLSTSACADYNRLDDFQKMTESGCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKACGSASVAISPSAPKTETVDPLKSKSEDVNESPVVHTEEAEMEESGRSATPVNSEQPDVLLSAVQTEEQVGKEETEPQPDADGTVLEEDSEVEKLKKMIDSLTEKLEKRETQLLSTSKEKARLEEAYDNLKDEMFRVKEETSSISSLKEEFAQRIADAEKKLQVACKERDAAKKEVKTVKEELATRLNTNETAELLKEKEEQIKGLMEEGEKLSKQQLHNSNTIKKLRAKEKERENINTKQNKKIKELEEELQHLKQVLDGKEDLEKQHRDSIKQLNIVVERQEKDLAKLQAEVEDLEERNRSVQAALDSAYKELADLHKANATKDSEAQEAALSREMKAKEELGLALEKAKDEARQQQEALAIQVADLRLALQRAEQQAARKEDYLRQEISELQQRLQEAESRNQELSQSVTSATRPLLRQIENLQATLGAQTSAWEKLEKNLSDRLGESQTLLAAAAERERAATEELMSNKVQMSSTESQNSRLRQENSRLQAQVEMERNKLKKMEVENSRYEVELEELKDEYAKTLEDAKKEKALLTTQLEMEKMKIEQERKKAIFAQEAAKEKDRKSFTIETVSSTPTMSRSSSISGVDMAGLQTSFLSQDDPHDHSFGPTATSGSNLYDAIRMGAGSSIIENLQSQLKLREGEISHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRAQLKDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLKQRQN", "length": 1108, "header": "tr|A0A8V0ZBG5-1|A0A8V0ZBG5_CHICK Isoform 1 of TATA element modulatory factor 1 OS=Gallus gallus OX=9031 GN=TMF1 PE=1 SV=1 CANONICAL=A0A8V0ZBG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5/entry#A0A8V0Z5M4-1", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQAEESPWPDAVIPDYGDGTNSLISGGWDTSSWGLSSNTEPQNQPVSPTAITKPVRRAVVDESENFFSAFLSPTDVQSIQKSPVVSKPPAKSQRPKEEVKSTLKEPQHFSQLEVLVTTEAEVKDSSVGGLVDLKNRDSPKEKLGENSVLKSNAEHEESTNEVADKKASALNLKEPEDALNGKSNVGADRTGGALDSNSQPPNTGTKDAALETKEQKTEDRQSNTPSPPISTFSSGTSTTSDIEVLDHESVISESSVSSRQEAADSKSSLHLMQTSFQLLSTSACADYNRLDDFQKMTESGCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKACGSASVAISPSAPKTETVDPLKSKSEDVNESPVVHTEEAEMEESGRSATPVNSEQPDVLLSAVQTEEQVGKEETEPQPDADGTVLEEDSEVEKLKKMIDSLTEKLEKRETQLLSTSKEKARLEEAYDNLKDEMFRVKEETSSISSLKEEFAQRIADAEKKLQVACKERDAAKKEVKTVKEELATRLNTNETAELLKEKEEQIKGLMEEGEKLSKQQLHNSNTIKKLRAKEKERENINTKQNKKIKELEEELQHLKQVLDGKEDLEKQHRDSIKQLNIVVERQEKDLAKLQAEVEDLEERNRSVQAALDSAYKELADLHKANATKDSEAQEAALSREMKAKEELGLALEKAKDEARQQQEALAIQVADLRLALQRAEQQAARKEDYLRQEISELQQRLQEAESRNQELSQSVTSATRPLLRQIENLQATLGAQTSAWEKLEKNLSDRLGESQTLLAAAAERERAATEELMSNKVQMSSTESQNSRLRQENSRLQAQVEMERNKLKKMEVENSRYEVELEELKDEYAKTLEDAKKEKALLTTQLEMEKMKIEQERKKAIFAQEAAKEKDRKSFTIETVSSTPTMSRSSSISGVDMAGLQTSFLSQDDPHDHSFGPTATSGSNLYDAIRMGAGSSIIENLQSQLKLREGEISHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRAQLKDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLKQRQN", "length": 1105, "header": "tr|A0A8V0Z5M4-1|A0A8V0ZBG5_CHICK Computationally mapped isoform of TATA element modulatory factor 1 OS=Gallus gallus OX=9031 GN=TMF1 PE=1 SV=1 CANONICAL=A0A8V0ZBG5-1" }, "locus": { "chromosome": "12", "start_pos": 15491298, "end_pos": 15478667, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048414.1", "url": "https://www.ensembl.org/id/ENSGALT00010048414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028544.1", "url": "https://www.ensembl.org/id/ENSGALP00010028544.1" } ] } }, { "isoform_ac": "A0A8V0ZBG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5/entry#A0A8V0ZBG0-1", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQAEESPWPDAVIPDYGDGTNSLISGGWDTSSWGLSSNTEPQNQPVSPTAITKPVRRAVVDESENFFSAFLSPTDVQSIQKSPVVSKPPAKSQRPKEEVKSTLKEPQHFSQLEVLVTTEAEVKDSSVGGLVDLKNRDSPKEKLGENSVLKSNAEHEESTNEVADKKASALNLKEPEDALNGKSNVGADRTGGALDSNSQPPNTGTKDAALETKEQKTEDRQSNTPSPPISTFSSGTSTTSDIEVLDHESVISESSVSSRQEAADSKSSLHLMQTSFQLLSTSACADYNRLDDFQKMTESGCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKACGSASVAISPSAPKTETVDPLKSKSEDVNESPVVHTEEAEMEESGRSATPVNSEQPDVLLSAVQTEEQVGKEETEPQPDADGTVLEEDSEVEKLKKMIDSLTEKLEKRETQLLSTSKEKARLEEAYDNLKDEMFRVKEETSSISSLKEEFAQRIADAEKKLQVACKERDAAKKEVKTVKEELATRLNTNETAELLKEKEEQIKGLMEEGEKLSKQQLHNSNTIKKLRAKEKERENINTKQNKKIKELEEELQHLKQVLDGKEDLEKQHRDSIKQLNIVVERQEKDLAKLQAEVEDLEERNRSVQAALDSAYKELADLHKANATKDSEAQEAALSREMKAKEELGLALEKAKDEARQQQEALAIQVADLRLALQRAEQQAARKEDYLRQEISELQQRLQEAESRNQELSQSVTSATRPLLRQIENLQATLGAQTSAWEKLEKNLSDRLGESQTLLAAAAERERAATEELMSNKVQMSSTESQNSRLRQENSRLQAQVEMERNKLKKMEVENSRYEVELEELKDEYAKTLEDAKKEKALLTTQLEMEKMKIEQERKKAIFAQEAAKEKDRKSFTIETVSSTPTMSRSSSISGVDMAGLQTSFLSQDDPHDHSFGPTATSGSNLYDAIRMGAGSSIIENLQSQLKLREGEISHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRAQLKVSAFVL", "length": 1064, "header": "tr|A0A8V0ZBG0-1|A0A8V0ZBG0_CHICK Computationally mapped isoform of TATA element modulatory factor 1 OS=Gallus gallus OX=9031 GN=TMF1 PE=1 SV=1 CANONICAL=A0A8V0ZBG5-1" }, "locus": { "chromosome": "12", "start_pos": 15491298, "end_pos": 15479524, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048400.1", "url": "https://www.ensembl.org/id/ENSGALT00010048400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028536.1", "url": "https://www.ensembl.org/id/ENSGALP00010028536.1" } ] } }, { "isoform_ac": "A0A8V0ZBG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5/entry#A0A8V0ZBG5-1", "sequence": { "sequence": "MRGIDGPGRPLHFWEPRTALLDASAEAEVVPHRHDRYRGGSGGGTPSAMTGTNSLISGGWDTSSWGLSSNTEPQNQPVSPTAITKPVRRAVVDESENFFSAFLSPTDVQSIQKSPVVSKPPAKSQRPKEEVKSTLKEPQHFSQLEVLVTTEAEVKDSSVGGLVDLKNRDSPKEKLGENSVLKSNAEHEESTNEVADKKASALNLKEPEDALNGKSNVGADRTGGALDSNSQPPNTGTKDAALETKEQKTEDRQSNTPSPPISTFSSGTSTTSDIEVLDHESVISESSVSSRQEAADSKSSLHLMQTSFQLLSTSACADYNRLDDFQKMTESGCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKACGSASVAISPSAPKTETVDPLKSKSEDVNESPVVHTEEAEMEESGRSATPVNSEQPDVLLSAVQTEEQVGKEETEPQPDADGTVLEEDSEVEKLKKMIDSLTEKLEKRETQLLSTSKEKARLEEAYDNLKDEMFRVKEETSSISSLKEEFAQRIADAEKKLQVACKERDAAKKEVKTVKEELATRLNTNETAELLKEKEEQIKGLMEEGEKLSKQQLHNSNTIKKLRAKEKERENINTKQNKKIKELEEELQHLKQVLDGKEDLEKQHRDSIKQLNIVVERQEKDLAKLQAEVEDLEERNRSVQAALDSAYKELADLHKANATKDSEAQEAALSREMKAKEELGLALEKAKDEARQQQEALAIQVADLRLALQRAEQQAARKEDYLRQEISELQQRLQEAESRNQELSQSVTSATRPLLRQIENLQATLGAQTSAWEKLEKNLSDRLGESQTLLAAAAERERAATEELMSNKVQMSSTESQNSRLRQENSRLQAQVEMERNKLKKMEVENSRYEVELEELKDEYAKTLEDAKKEKALLTTQLEMEKMKIEQERKKAIFAQEAAKEKDRKSFTIETVSSTPTMSRSSSISGVDMAGLQTSFLSQDDPHDHSFGPTATSGSNLYDAIRMGAGSSIIENLQSQLKLREGEISHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRAQLKDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLKQRQN", "length": 1108, "header": "tr|A0A8V0ZBG5-1|A0A8V0ZBG5_CHICK Isoform 1 of TATA element modulatory factor 1 OS=Gallus gallus OX=9031 GN=TMF1 PE=1 SV=1 CANONICAL=A0A8V0ZBG5-1" }, "locus": { "chromosome": "12", "start_pos": 15491684, "end_pos": 15478667, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048407.1", "url": "https://www.ensembl.org/id/ENSGALT00010048407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028541.1", "url": "https://www.ensembl.org/id/ENSGALP00010028541.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426072", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZ48-1", "protein_name": "TATA element modulatory factor 1", "gene_name": "Tmf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGISPSVSGGWDTSTWGLNSSSEPQSSPTASQAITKPVRRTVVDESENFFSAFLSPSDVQTIQKSPVVSKPPAKSQRPEEEVKSSLQEPSSPGQSRTSETAESEATDSACVSGETPAVGTPSPVPEGKREETASEESEGKVPTVRAKASESVVKVNTAEDVSPTSTQSLTTETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYGRLDDFQKLSESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGRGYALVPIVVSPSAPKTKVVESTEENVEEEEGNETLIAPSEEAELEESGRSATPVNCDQPDTLASPTPVNVGPSASGPAAEDGEAAENHPKAPQLEQEDVGKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAERKAQLACKERDTAKKEMKTMKEELASRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNMIKKLRAKDKDNESVIAKLKKKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMNELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQETLALQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEMLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNALLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEEARKEKTLLSSQLEMERMKVEQERKKTIFTQETLKEKEHKPFSVSSTPTMSRSSSLSGVDMAGLQTSFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDACGNPIKPYTSGARLAVLCKKTR", "length": 1095 }, "evidence": [ { "id": "A0A8V0ZBG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B9EKI3-1", "protein_name": "TATA element modulatory factor", "gene_name": "Tmf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGEPGISPPVSGGWDTSTWGLNSTSSEPQSPPTASQAITKPVRRTVVDESENFFSAFLSPSDAHTIQKSPVVSKPPSKSQRPEEEVKSSLQESSSPGQSRVSETAEVRDSVCVSGETSAVGTPSPVPEDKHEETAGEESEVKVPTVRLKASENVVNVNTTEDVSTTSTQSLTAETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYSRLDDFQKLNESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGKGYALVPIIVSPSTPKTKVVESTEENAEEEEGNETLVAPSEEAELEESGRSATPVNCDQPDILASPTAGSGGHSASGPATEQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQRLS", "length": 1091 }, "evidence": [ { "id": "A0A8V0ZBG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1REB9-1", "protein_name": "TATA element modulatory factor", "gene_name": "tmf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWFNASHLSSFAKQALTTAQKSIDRVLDIKEEEWGDTTGQNFPDPPGKPAPTGWGMNQWNSPTEEQTTSPPPSSEAITTPVTRTVVDESEDFFSAFLPPGDVQAVSNTKVVSVAPAKSNRRLREKADKDKELVDNDLQGQAELSKSSSQEITEIKPAGAELSEQNSSTVEEQMQPELGIPASGVAPEQAVEQESIEDQTESDGLVLTLDVPLTNVPSFSSEGESVDSFDPPLNVETKNPDKTLPVPPKEIILESKDAKSEDRQSDTPSPPVSAFSSGTSTTSDIEVLDHESVLSESSASSRQETAEAKAGLHLMQGSFQLLSASTCSDFPRLDEYPKLTESCGSSSDAFERIDSFSVQSLDSRSVSEVNSDDEIPGNRTLASITAGPLPAPAESVPQTKQEEEEGMIESMNDQSLDDNEMEESGRSATPVNCEQVDELQEVDQEPEPDLTMSSQKIDVHETVTPLSTEEKPGDSPFQISELQKIIEELSGRLEKRESQLLAVSKDKARLEEECDNLKDEVISLKEESSSVQSLKDEFTQRIADAERKAQLSCKERDIAKKEIKGLREELASRLNSNETLELIKEKEEQIRELLEEGEKLSKQQLQHSNIIKKLRVKERESDAQIAKQTKKLKEQEEELKLLQQVMDGKEEIEKQHRENIKKLNAVVERQEKELSKLQTSSEELQEKSRSLQAALDSSYKELAELHKANASKDSEAQELALSREVQAKEELSLALEKVQEDSRLQQEALANQVADLRVALQRAEQQQAKKEDYLREEISELQQRIQEAETRNQELSQSVTSATRPLLRQIENLQATLGAQTASWEKLEKNLSDRLADAQAQLAVSVEKERSATEELLAIRAQITSFESQASLLRQEKGRLQGQLDAERMRREKLEDDLSRERVELENLKGEYARVSEDSKKEKLLLTNQLEMEKMKVEQEKKKCYLAQEALKEKERKSHQSVTDAPASSTPSLSRSSSVSGADHAGLPSSFFSQQEDSLDHSFNTMTMSISGTNLYEAARLGGGSSVIESLQSQLKLREGEITQLQMEIASLERSRTVMSEELIRLTNENDEMESKVKEIPRLKVQLKDLEQRHNTILQMYGEKAEEAEELRLDLEDVKNMYKLQIDELLKNQKQ", "length": 1135 }, "evidence": [ { "id": "A0A8V0ZBG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P82094-1", "protein_name": "TATA element modulatory factor", "gene_name": "TMF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQSLS", "length": 1093 }, "evidence": [ { "id": "A0A8V0ZBG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" }, { "name": "nuclear androgen receptor binding", "id": "GO:0050681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" }, { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG5" }, { "id": "PF12325", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12325" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TATA element modulatory factor 1 TATA binding", "eco_id": "ECO_0000259", "start_pos": 993, "end_pos": 1102, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 45 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 809, "end_pos": 811 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { 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"url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z703", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z703-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z703-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Y9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z803", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z803", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z803-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z803-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGMAPPLFEPKERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLHNHVPRFLSCSDDIVENKGRLNAAMLKTSVF", "length": 280, "header": "tr|A0A8V0Z7Z4-1|A0A8V0Z7Z4_CHICK Isoform 1 of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z6F3-1", "sequence": { "sequence": "MNGMAPPLFEPKERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRDAVLFHQFNQLKLSLEE", "length": 267, "header": "tr|A0A8V0Z6F3-1|A0A8V0Z7Z4_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25944721, "end_pos": 25937040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044799.1", "url": "https://www.ensembl.org/id/ENSGALT00010044799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026721.1", "url": "https://www.ensembl.org/id/ENSGALP00010026721.1" } ] } }, { "isoform_ac": "A0A8V0Z703-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z703-1", "sequence": { "sequence": "AERSSASKVTGGVHRVPSLDDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRSDLQLSESGSDSDD", "length": 249, "header": "tr|A0A8V0Z703-1|A0A8V0Z7Z4_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25949498, "end_pos": 25937355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044806.1", "url": "https://www.ensembl.org/id/ENSGALT00010044806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026728.1", "url": "https://www.ensembl.org/id/ENSGALP00010026728.1" } ] } }, { "isoform_ac": "A0A8V0Z7Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z7Y9-1", "sequence": { "sequence": "MNGMAPPLFEPKERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKISRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRKYKDCSFLSMQFQTSRF", "length": 268, "header": "tr|A0A8V0Z7Y9-1|A0A8V0Z7Y9_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25944241, "end_pos": 25937040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044795.1", "url": "https://www.ensembl.org/id/ENSGALT00010044795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026717.1", "url": "https://www.ensembl.org/id/ENSGALP00010026717.1" } ] } }, { "isoform_ac": "A0A8V0Z7Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z7Z4-1", "sequence": { "sequence": "MNGMAPPLFEPKERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLHNHVPRFLSCSDDIVENKGRLNAAMLKTSVF", "length": 280, "header": "tr|A0A8V0Z7Z4-1|A0A8V0Z7Z4_CHICK Isoform 1 of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25948494, "end_pos": 25937040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044800.1", "url": "https://www.ensembl.org/id/ENSGALT00010044800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026722.1", "url": "https://www.ensembl.org/id/ENSGALP00010026722.1" } ] } }, { "isoform_ac": "A0A8V0Z7Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z7Z9-1", "sequence": { "sequence": "GERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRSDLQLSESGSDSDD", "length": 253, "header": "tr|A0A8V0Z7Z9-1|A0A8V0Z7Z9_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25949498, "end_pos": 25937020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044805.1", "url": "https://www.ensembl.org/id/ENSGALT00010044805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026727.1", "url": "https://www.ensembl.org/id/ENSGALP00010026727.1" } ] } }, { "isoform_ac": "A0A8V0Z803-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0Z803-1", "sequence": { "sequence": "MNGMAPPLFEPKERVLQLGETFEKQPRCAFHTVRYDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKISRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRSDLQLSESGSDSDD", "length": 265, "header": "tr|A0A8V0Z803-1|A0A8V0Z803_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25949498, "end_pos": 25937040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044810.1", "url": "https://www.ensembl.org/id/ENSGALT00010044810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026732.1", "url": "https://www.ensembl.org/id/ENSGALP00010026732.1" } ] } }, { "isoform_ac": "A0A8V0ZDU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4/entry#A0A8V0ZDU7-1", "sequence": { "sequence": "NRSVPFLCWGASELNAGSRWGLVRADHKGTITSQGLSKAAYCLSENDFKPASIDTACEGDLEVGKGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKIRAEGSSKVQSRIEQQQQQIRNSSKTPNNIKNSPPKDKMFPSSPMDDIERELKAEASIMDQLSSSDSSSDSKSSSSSSSSSENSSSDSEDEEARPSLPMSMPYLQPQPTLSAIPHQAVPDKDASHNRSQENSGHMMNTLRSDLQLSESGSDSDD", "length": 275, "header": "tr|A0A8V0ZDU7-1|A0A8V0ZDU7_CHICK Computationally mapped isoform of ELL associated factor 2 OS=Gallus gallus OX=9031 GN=EAF2 PE=3 SV=1 CANONICAL=A0A8V0Z7Z4-1" }, "locus": { "chromosome": "7", "start_pos": 25949498, "end_pos": 25938130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044803.1", "url": "https://www.ensembl.org/id/ENSGALT00010044803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026725.1", "url": "https://www.ensembl.org/id/ENSGALP00010026725.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "super elongation complex", "id": "GO:0032783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z4" }, { "id": "PF09816", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09816" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription elongation factor Eaf N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 113, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8N4-1", "uniprot_ac": "A0A8V0Z8N4", "uniprot_id": "A0A8V0Z8N4_CHICK", "mass": { "chemical_mass": 55766.0, "monoisotopic_mass": 55766.0 }, "refseq": {}, "gene_names": [ { "name": "IL13RA2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4" } ] } ], "protein_names": [ { "name": "Interleukin 13 receptor subunit alpha 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL13RA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4", "locus": { "chromosome": "4", "start_pos": 2790288, "end_pos": 2810374, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018665", "url": "https://www.ensembl.org/id/ENSGALG00010018665" } ] } } ], "crossref": [ { "id": "A0A8V0Z8N4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8N4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422219", "url": "https://www.ncbi.nlm.nih.gov/gene/422219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422219", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPIPSQC", "url": "https://omabrowser.org/oma/group/GPIPSQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z749", "url": "https://www.orthodb.org/?gene=A0A8V0Z749", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7P4", "url": "https://www.orthodb.org/?gene=A0A8V0Z7P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8N0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8N4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z749", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z749", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z749-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z749-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSQISAGGSEQAVFFPFLFLHAHPIHRTLPGRLLGCNCLKLSRTRNRCEAFPFISLLHFAFFFFLQLVDTFSLHVTWSRGKPGAAAREFHGPTAVIEAFHHHTAPAMLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 498, "header": "tr|A0A8V0Z8N4-1|A0A8V0Z8N4_CHICK Isoform 1 of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z749-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#A0A8V0Z749-1", "sequence": { "sequence": "MLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYESVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 376, "header": "tr|A0A8V0Z749-1|A0A8V0Z8N4_CHICK Computationally mapped isoform of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "locus": { "chromosome": "4", "start_pos": 2798818, "end_pos": 2790556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045168.1", "url": "https://www.ensembl.org/id/ENSGALT00010045168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026975.1", "url": "https://www.ensembl.org/id/ENSGALP00010026975.1" } ] } }, { "isoform_ac": "A0A8V0Z7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#A0A8V0Z7P4-1", "sequence": { "sequence": "RHGLRAGGATPGDALGEIRTLKLILVIGLGVIVKSLLSHWKRIFGEHNSHPEECRLLYPLAGAGGYLFLTRHLVQRKTRSCCVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 435, "header": "tr|A0A8V0Z7P4-1|A0A8V0Z7P4_CHICK Computationally mapped isoform of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "locus": { "chromosome": "4", "start_pos": 2810290, "end_pos": 2790556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045171.1", "url": "https://www.ensembl.org/id/ENSGALT00010045171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026977.1", "url": "https://www.ensembl.org/id/ENSGALP00010026977.1" } ] } }, { "isoform_ac": "A0A8V0Z8M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#A0A8V0Z8M1-1", "sequence": { "sequence": "MLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 391, "header": "tr|A0A8V0Z8M1-1|A0A8V0Z8M1_CHICK Computationally mapped isoform of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "locus": { "chromosome": "4", "start_pos": 2798818, "end_pos": 2790556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045141.1", "url": "https://www.ensembl.org/id/ENSGALT00010045141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026961.1", "url": "https://www.ensembl.org/id/ENSGALP00010026961.1" } ] } }, { "isoform_ac": "A0A8V0Z8N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#A0A8V0Z8N0-1", "sequence": { "sequence": "MRILYTGHSQLVDTFSLHVTWSRGKPGAAAREFHGPTAVIEAFHHHTAPAMLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 441, "header": "tr|A0A8V0Z8N0-1|A0A8V0Z8N0_CHICK Computationally mapped isoform of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "locus": { "chromosome": "4", "start_pos": 2806297, "end_pos": 2790556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045154.1", "url": "https://www.ensembl.org/id/ENSGALT00010045154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026966.1", "url": "https://www.ensembl.org/id/ENSGALP00010026966.1" } ] } }, { "isoform_ac": "A0A8V0Z8N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4/entry#A0A8V0Z8N4-1", "sequence": { "sequence": "MSSQISAGGSEQAVFFPFLFLHAHPIHRTLPGRLLGCNCLKLSRTRNRCEAFPFISLLHFAFFFFLQLVDTFSLHVTWSRGKPGAAAREFHGPTAVIEAFHHHTAPAMLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 498, "header": "tr|A0A8V0Z8N4-1|A0A8V0Z8N4_CHICK Isoform 1 of Interleukin 13 receptor subunit alpha 2 OS=Gallus gallus OX=9031 GN=IL13RA2 PE=4 SV=1 CANONICAL=A0A8V0Z8N4-1" }, "locus": { "chromosome": "4", "start_pos": 2806361, "end_pos": 2790556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045161.1", "url": "https://www.ensembl.org/id/ENSGALT00010045161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026971.1", "url": "https://www.ensembl.org/id/ENSGALP00010026971.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422219", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RWT5-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "IL13RA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFIHVNIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDNFKECTVEYELKYRNIDSESWKTIITKNLHYKDGFDLNKGVEAKIHTLLPGQCTNGSEVQSSWSETTYWTLPQGNLETKIQDMDCVYYNWQYLLCSWKPGMGVHFDTNYNLFYWYEGLDHALQCADYIKTNGKNTGCRFPYLESSDYKDFYICVNGSSESQSIRPSYFIFQLQNIVKPLPPDYLSLTVKNSEEVNLKWSIPRGPIPSQCFIYEIEFTEDDTTWVTTTDENEIYITRTSNESHRLCFSVRSKMNIYCSDDGIWSEWSDEQCWKGDIWKETLVFFLIPFAFVSLLVLLITCLLLYKQKNLLKMIFHTKKEAFSHQDTLC", "length": 387 }, "evidence": [ { "id": "A0A8V0Z8N4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G5E5N7-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "IL13RA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRTLQLEQSGNFKVLNLREMAFIHLDIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFQIVDPGYLGYLYLQWQPPVSLDNFNKCTVEYELKYRNVDSESWRTIITKNLLYKDGFDLNKGVEAKIHTLLPRQCTNGSEVQSSWSEATYWISSQGNLDTKIQDMDCVYYNWQYLLCSWKPGMGAHLDSNYRLYYWYEGLDHVLECIDYIQAKGKNIGCRFPYLESSDYKDFYICVNGSSESQLIRPSYFIFQLQNIVKPLPPDYLSLTMKNSEVNLKWSIPRGPIPAKCLIYEIEFTEDDTAWVTTTIENEIYITRTSNESLQLCFLVRSKMNIYCADDGIWSEWSDEQCWKGDIWKEILLFFLVPFVLVSLFVLIVTCTLLYKQRNLLKMVFHTEKRSPF", "length": 399 }, "evidence": [ { "id": "A0A8V0Z8N4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88786-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "Il13ra2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFVHIRCLCFILLCTITGYSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEGYTGPDSKIIFIVPVCLFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC", "length": 383 }, "evidence": [ { "id": "A0A8V0Z8N4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14627-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "IL13RA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT", "length": 380 }, "evidence": [ { "id": "A0A8V0Z8N4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHK6-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "Il13ra2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMAVNTRCLCLFLLCTITGHSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVMDNFKECKLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWTEASYGIADEGSLGTKIQDMKCIYYNWQYLVCSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCKLSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPSCYTYEIVVREDDISWESATDKNDMKLKRRANESEDLCFFVRCKINIYCADDGIWSEWSEEECWEGYTGPDSKIVFIVPVCLFFIFLLLLLCLIVEKEDPEPTLSLHVDLNKEMYAYEETLC", "length": 385 }, "evidence": [ { "id": "A0A8V0Z8N4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N4" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 247, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 315, "end_pos": 317 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7H0-1", "uniprot_ac": "A0A8V0Z7H0", "uniprot_id": "A0A8V0Z7H0_CHICK", "mass": { "chemical_mass": 93221.0, "monoisotopic_mass": 93221.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF148", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ] } ], "protein_names": [ { "name": "Zinc finger protein 148", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H5#function" }, { "database": "UniProtKB", "id": "ARBA00060069", "url": "https://www.uniprot.org/uniprotkb/ARBA00060069#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF148", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0", "locus": { "chromosome": "7", "start_pos": 27658058, "end_pos": 27689743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020429", "url": "https://www.ensembl.org/id/ENSGALG00010020429" } ] } } ], "crossref": [ { "id": "A0A8V0Z7H0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7H0", "database": "AlphaFoldDB", "categories": [] }, { "id": "424259", "url": "https://www.ncbi.nlm.nih.gov/gene/424259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424259", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPMNTEI", "url": "https://omabrowser.org/oma/group/QPMNTEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7H0", "url": "https://www.orthodb.org/?gene=A0A8V0Z7H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7H5", "url": "https://www.orthodb.org/?gene=A0A8V0Z7H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEB7", "url": "https://www.orthodb.org/?gene=A0A8V0ZEB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYTCVQFPEFGKQRGTALEQSPCTGLILQLICSADVLLHLRMNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPISVKQEITFTDASEQQKRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 833, "header": "tr|A0A8V0Z7H0-1|A0A8V0Z7H0_CHICK Isoform 1 of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#A0A8V0Z7H0-1", "sequence": { "sequence": "MYTCVQFPEFGKQRGTALEQSPCTGLILQLICSADVLLHLRMNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPISVKQEITFTDASEQQKRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 833, "header": "tr|A0A8V0Z7H0-1|A0A8V0Z7H0_CHICK Isoform 1 of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "locus": { "chromosome": "7", "start_pos": 27688114, "end_pos": 27659028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049389.1", "url": "https://www.ensembl.org/id/ENSGALT00010049389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029194.1", "url": "https://www.ensembl.org/id/ENSGALP00010029194.1" } ] } }, { "isoform_ac": "A0A8V0Z7H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#A0A8V0Z7H5-1", "sequence": { "sequence": "MNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPISVKQEITFTDASEQQKRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 764, "header": "tr|A0A8V0Z7H5-1|A0A8V0Z7H5_CHICK Computationally mapped isoform of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "locus": { "chromosome": "7", "start_pos": 27672110, "end_pos": 27659028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049399.1", "url": "https://www.ensembl.org/id/ENSGALT00010049399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029199.1", "url": "https://www.ensembl.org/id/ENSGALP00010029199.1" } ] } }, { "isoform_ac": "A0A8V0ZDA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#A0A8V0ZDA1-1", "sequence": { "sequence": "MTGRLCVLASSMYLGLPCFHILECPDQISLLLLHLRMNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPISVKQEITFTDASEQQKRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 828, "header": "tr|A0A8V0ZDA1-1|A0A8V0ZDA1_CHICK Computationally mapped isoform of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "locus": { "chromosome": "7", "start_pos": 27688645, "end_pos": 27659028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049394.1", "url": "https://www.ensembl.org/id/ENSGALT00010049394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029196.1", "url": "https://www.ensembl.org/id/ENSGALP00010029196.1" } ] } }, { "isoform_ac": "A0A8V0ZEB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#A0A8V0ZEB7-1", "sequence": { "sequence": "MNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPISVKQEITFTDASEQQKRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 792, "header": "tr|A0A8V0ZEB7-1|A0A8V0ZEB7_CHICK Computationally mapped isoform of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "locus": { "chromosome": "7", "start_pos": 27672110, "end_pos": 27659028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049398.1", "url": "https://www.ensembl.org/id/ENSGALT00010049398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029198.1", "url": "https://www.ensembl.org/id/ENSGALP00010029198.1" } ] } }, { "isoform_ac": "A0A8V0ZEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0/entry#A0A8V0ZEP3-1", "sequence": { "sequence": "MNIEDKLGGLFLKCGGIDQMQSSRAMVGMGAVSDQSGVSGERQEAVLQDRTMAHQEILAPDEVLQESELRQQEMISHDELMVHEETVKNDDDMDTQDRLPQGLQYAVNVPILTINEDGSLGLKTHKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENRDKKPNRSATKVGFLPSEEDSGFSTPMKDSSLPKKKRQKTEKTKSGDKDGTDKSEQKKDKNDYLPLYSASTKVKDEYMVAEYAVEMPHSSVSGSHLEEANSGEIHPPKLVLKKVNSKRSLKQPLEQSQSISPLSTYEDSKVSKYTFDLVDKQSLLDSEGNADIDQVDTLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVSTIASQPSVTQAAVASVIDETATASILDTQALNVEIKGSHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVSEVTQSETVGTSSQASSSDKASMLQEYSKFLQQALDRTSQNDAYLNNPSLNFVTDNQTLTTQPAFPSIEKQVYTSIPVNSFRSGMNSPLRTTPDKSHFGLMVGDSQHPFPFSGDEANHSSSSSTQDFLEQVTSQKKAEAQPVHQAYQISSFEQPFRAQYHGARAGISSQFSTANGQVNLRGPGTSADFPEFPLVNVNDSRAGMTSSPDATTGQTFG", "length": 750, "header": "tr|A0A8V0ZEP3-1|A0A8V0ZEP3_CHICK Computationally mapped isoform of Zinc finger protein 148 OS=Gallus gallus OX=9031 GN=ZNF148 PE=3 SV=1 CANONICAL=A0A8V0Z7H0-1" }, "locus": { "chromosome": "7", "start_pos": 27672110, "end_pos": 27659028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049395.1", "url": "https://www.ensembl.org/id/ENSGALT00010049395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029197.1", "url": "https://www.ensembl.org/id/ENSGALP00010029197.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424259", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M2M3-1", "protein_name": "Zinc finger protein 148", "gene_name": "ZNF148", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSTVSGELQESVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESSLDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFPEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794 }, "evidence": [ { "id": "A0A8V0Z7H0", "url": "https://omabrowser.org/oma/group/A0A8V0Z7H0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0MS83-1", "protein_name": "Zinc finger protein 148", "gene_name": "znf148", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNIDDKLEGMLLKYSPVGLQHPSRGLGPSRVDGRGRRGSLDMTLGERSLANHPLLAEDDDDEDEEEDDDDDLAGEGLTSHDLISQDDLMVHEETVKNDGQDEAAFSHRISNKLHYTLSMPVNIKQEMKVPDSLILNKKEKKPGRDPSDCHKKKKRKQRSPAKILTINEDGSLGHQNPKSHICEHCNAAFRTNYHLQRHVFIHTGEKPFQCNQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMKFIQKYHMERHKRTHSGEKPYQCDYCHQFFSRTDRVLKHRRMCHENKDRKVQKTAVKDSPLRTPENLGFSFPAKDCTLPKKKRQKTSDKSRASITNPAVDKVVEADMDEKTEDRLAKSECLPLYAVATKVKDEYVVTDYSVELPDSPPGSRHLAGEESNDEIISPPKLVLKKIASRRGFKQQALEQSQSLSPLSSFEESKVTRYTFEIVDNKGLLDVETNPDMESVEALQVGQAKPTGSSTNYDDAMQFVKKRRYLQAATANTSRDYALNVSSIVSQSSVTQASVATVIDETVPATILSETQTLNVEIKSSNEKNVLPDEVLQTLLDHYSNKANGQAEISFSVADTEVTSSISINSSDESSPAEALVTSSQAPPTEKASLLQEYSKFLQQALERTSQNDTYLNNQSLTFVNDSASLAGQPLFSTEKQFTSPPRFRPTMNSPLRSTLEKPNFNLLVDTQHSFSFSGDETNPSSVSPTEDFLDQVTSPKKTDPQSISQTFQITTFDQNFRSQFPSSRSGISPQFSIASGQVTLRGHGGADFPEFSLVNETRTQLTSSPDATSSQTFG", "length": 808 }, "evidence": [ { "id": "A0A8V0Z7H0", "url": "https://omabrowser.org/oma/group/A0A8V0Z7H0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q61624-1", "protein_name": "Zinc finger protein 148", "gene_name": "Znf148", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESVLDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQSQTISPLSSYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKPNGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794 }, "evidence": [ { "id": "A0A8V0Z7H0", "url": "https://omabrowser.org/oma/group/A0A8V0Z7H0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62806-1", "protein_name": "Zinc finger protein 148", "gene_name": "Znf148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQTDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKSSGMDKESVLDKSDTKKDRNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDENTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794 }, "evidence": [ { "id": "A0A8V0Z7H0", "url": "https://omabrowser.org/oma/group/A0A8V0Z7H0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UQR1-1", "protein_name": "Zinc finger protein 148", "gene_name": "ZNF148", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESALDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "length": 794 }, "evidence": [ { "id": "A0A8V0Z7H0", "url": "https://omabrowser.org/oma/group/A0A8V0Z7H0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7H0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 238, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 814, "end_pos": 816 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7I3-1", "uniprot_ac": "A0A8V0Z7I3", "uniprot_id": "A0A8V0Z7I3_CHICK", "mass": { "chemical_mass": 63968.0, "monoisotopic_mass": 63968.0 }, "refseq": { "ac": "XP_040503687", "name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503687" }, "gene_names": [ { "name": "WFIKKN1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ] }, { "name": "WFIKKN1", "type": "synonym", "evidence": [ { "id": "XP_040503687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503687" } ] } ], "protein_names": [ { "name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_040503687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503687" } ] }, { "name": "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503687" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WFIKKN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3", "locus": { "chromosome": "14", "start_pos": 13575751, "end_pos": 13570126, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018838", "url": "https://www.ensembl.org/id/ENSGALG00010018838" } ] } } ], "crossref": [ { "id": "A0A8V0Z7I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000044", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000044", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03575", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03575", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22606", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22606", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429301", "url": "https://www.ncbi.nlm.nih.gov/gene/429301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NFIMRPD", "url": "https://omabrowser.org/oma/group/NFIMRPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7I3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMX3", "url": "https://www.orthodb.org/?gene=F1NMX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45938:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45938:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMX3", "url": "https://www.uniprot.org/uniprotkb/F1NMX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMX3-1", "url": "https://www.uniprot.org/uniprotkb/F1NMX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRRFDRPGPRSRPGGQQLGGAEPMRSALLLLLPLLAAAAGLSLQQARMRHLGVCPNQLNPNLWVDAQSTCERECQADQDCEGFEKCCTNVCGLRSCVAARFADGSLLALELGRGPSCESFVCAQQGSDCDIWDGQPVCKCKDRCEKEPNFTCASDGLTYYNKCYMDAEACLRGTRLTTVPCKHVFTWPDTSPVPRETTARPTPGAGPEPPVPPALYSNPFHQSVRAGGTVSFRCDVSGRPRPDITWEKQSDRAENFIMRPDQMYGNVVVTNIGQLVIYNARHEDAGIYTCTARNAAGLLRADFPLSVLKREPGAAPRPGSPQPFPGAECLKEPDRRRCEATEVRWHFDAKQGSCVTFRYGGCGANRNHFETYEECRAACVGSARPTCLLPMVQGPCQNWEPRWAYNYVLKQCHSFVYGGCEGNNNNFDSKETCEDVCPFPKSLQCKACRLKSKMVLSLCRSDFAIVGRLMEIVEDQDSGIARFALEDVLKDEKMGLKFFNIKYLEVTLVDMDWSCPCPNMTAEDGPLIIMGAVHDGMATLDPGSYVRAANDKRVKKIYELMEKKTCDLLNRFQD", "length": 576, "header": "tr|A0A8V0Z7I3-1|A0A8V0Z7I3_CHICK Isoform 1 of WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 OS=Gallus gallus OX=9031 GN=WFIKKN1 PE=1 SV=1 CANONICAL=A0A8V0Z7I3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3/entry#A0A8V0Z7I3-1", "sequence": { "sequence": "MPRRRFDRPGPRSRPGGQQLGGAEPMRSALLLLLPLLAAAAGLSLQQARMRHLGVCPNQLNPNLWVDAQSTCERECQADQDCEGFEKCCTNVCGLRSCVAARFADGSLLALELGRGPSCESFVCAQQGSDCDIWDGQPVCKCKDRCEKEPNFTCASDGLTYYNKCYMDAEACLRGTRLTTVPCKHVFTWPDTSPVPRETTARPTPGAGPEPPVPPALYSNPFHQSVRAGGTVSFRCDVSGRPRPDITWEKQSDRAENFIMRPDQMYGNVVVTNIGQLVIYNARHEDAGIYTCTARNAAGLLRADFPLSVLKREPGAAPRPGSPQPFPGAECLKEPDRRRCEATEVRWHFDAKQGSCVTFRYGGCGANRNHFETYEECRAACVGSARPTCLLPMVQGPCQNWEPRWAYNYVLKQCHSFVYGGCEGNNNNFDSKETCEDVCPFPKSLQCKACRLKSKMVLSLCRSDFAIVGRLMEIVEDQDSGIARFALEDVLKDEKMGLKFFNIKYLEVTLVDMDWSCPCPNMTAEDGPLIIMGAVHDGMATLDPGSYVRAANDKRVKKIYELMEKKTCDLLNRFQD", "length": 576, "header": "tr|A0A8V0Z7I3-1|A0A8V0Z7I3_CHICK Isoform 1 of WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 OS=Gallus gallus OX=9031 GN=WFIKKN1 PE=1 SV=1 CANONICAL=A0A8V0Z7I3-1" }, "locus": { "chromosome": "14", "start_pos": 13573145, "end_pos": 13570653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045476.1", "url": "https://www.ensembl.org/id/ENSGALT00010045476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027130.1", "url": "https://www.ensembl.org/id/ENSGALP00010027130.1" } ] } }, { "isoform_ac": "F1NMX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3/entry#F1NMX3-1", "sequence": { "sequence": "MVGTLRGWEHPARGRGWRRDQHWGRGERSGRCCGADRCPPPGQDCEGFEKCCTNVCGLRSCVAARFADGSLLALELGRGPSCESFVCAQQGSDCDIWDGQPVCKCKDRCEKEPNFTCASDGLTYYNKCYMDAEACLRGTRLTTVPCKHVFTWPDTSPVPRETTARPTPGAGPEPPVPPALYSNPFHQSVRAGGTVSFRCDVSGRPRPDITWEKQSDRAENFIMRPDQMYGNVVVTNIGQLVIYNARHEDAGIYTCTARNAAGLLRADFPLSVLKREPGAAPRPGSPQPFPGAECLKEPDRRRCEATEVRWHFDAKQGSCVTFRYGGCGANRNHFETYEECRAACVGSARPTCLLPMVQGPCQNWEPRWAYNYVLKQCHSFVYGGCEGNNNNFDSKETCEDVCPFPKSLQCKACRLKSKMVLSLCRSDFAIVGRLMEIVEDQDSGIARFALEDVLKDEKMGLKFFNIKYLEVTLVDMDWSCPCPNMTAEDGPLIIMGAVHDGMATLDPGSYVRAANDKRVKKIYELMEKKTCDLLNRFQD", "length": 539, "header": "tr|F1NMX3-1|A0A8V0Z7I3_CHICK Computationally mapped isoform of WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 OS=Gallus gallus OX=9031 GN=WFIKKN1 PE=1 SV=5 CANONICAL=A0A8V0Z7I3-1" }, "locus": { "chromosome": "14", "start_pos": 13573145, "end_pos": 13571529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045481.1", "url": "https://www.ensembl.org/id/ENSGALT00010045481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027135.1", "url": "https://www.ensembl.org/id/ENSGALP00010027135.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 204, "start_aa": "Thr", "end_pos": 204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr204", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZU02-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "gene_name": "WFIKKN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPALRPLLPLFLLAGLTAGASLPPGPGDHPGVCPNQLSPNLWVDAQSTCERECGRDQDCAATEKCCTNVCGLQSCVAARFPGGSPAAPTLTASCEGVVCQQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLRLHVVPCKHILSWPPSSPEPPETTARPPPEDAPVPPALYSSPAPQAVYVGGTASLHCDVSGRPPPAVTWEKQSDQREHLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVEREPAGDGPAATPPAQCLPSTQACVGPPSSRVLWHFDPRRGGCMTFPAGSCARGAQGFETYEACQQACAHGPRDACMLPAVQGPCQGWEPRWAYSPLLQQCHPFVYSGCEGNGNNFESRESCEGACPVPRMPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAGSGGIARVALDDVLKDDKMGLRFLGTKYLEVTLSGMDRACPCPNVTAGDGPLVIMGEVRDGVAMLDAGSYVRAASEKRVKKISELLERKACELLNRFQD", "length": 548 }, "evidence": [ { "id": "A0A8V0Z7I3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7I3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C5J5-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "gene_name": "Wfikkn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAPQPLLPLLFAFVLIHLTSETNLLPEPGSHPGMCPNQLSPHLWVDAQSTCERECTRDQDCAASEKCCTNVCGLQSCVAARFPSGGPATPETAASCEDFQCPQQGSNCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHVVPCKHILSWPPSSPGPPETTARPTPGAAPMPPALYNSPSPQAVHVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAQLEDAGLYTCTARNAAGLLRADFPLSVLQRATTQDRDPGVLALAECQPDTQACVGPPTPHHVLWRFDPQRGSCMTFPALKCDGAARGFETYEACQQACVRGPGDVCALPPVQGPCQGWEPRWAYSPLLQQCHPFIYSGCEGNSNNFESRESCEDACPVPRTPPCRACRLKSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALDDVLKDDKMGLKFLGTKYLEVTLSGMDWACPCPNVTVGDGPLVIMGEVREGVAVLDANSYVRAASEKRVKKIVELLEKKACELLNRFQD", "length": 552 }, "evidence": [ { "id": "A0A8V0Z7I3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7I3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R0S6-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "gene_name": "Wfikkn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAPQPFLPLLFVFVLIHLTSETNLLPDPGSHPGMCPNELSPHLWVDAQSTCERECTGDQDCAASEKCCTNVCGLQSCVAARFPSGGPAVPETAASCEGFQCPQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHVVPCKHILSWPPSSPGPPETTARPTPGAAPMPPALYNSPSPQAVHVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAQLEDAGLYTCTARNAAGLLRADFPLSVLQRATTQDRDPGIPALAECQADTQACVGPPTPHHVLWRFDPQRGSCMTFPALRCDGAARGFETYEACQQACVRGPGDVCALPAVQGPCQGWEPRWAYSPLLQQCHPFVYSGCEGNSNNFETRESCEDACPVPRTPPCRACRLKSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALDDVLKDDKMGLKFLGTKYLEVTLSGMDWACPCPNVTAVDGPLVIMGEVREGVAVLDANSYVRAASEKRVKKIVELLEKKACELLNRFQD", "length": 552 }, "evidence": [ { "id": "A0A8V0Z7I3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7I3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NZ8-1", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1", "gene_name": "WFIKKN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRDQDCAAAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFVCPQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGTKYLEVTLSGMDWACPCPNMTAGDGPLVIMGEVRDGVAVLDAGSYVRAASEKRVKKILELLEKQACELLNRFQD", "length": 548 }, "evidence": [ { "id": "A0A8V0Z7I3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7I3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" }, { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7I3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"Ensembl Transcript", "id": "ENSGALT00010044641.1", "url": "https://www.ensembl.org/id/ENSGALT00010044641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026581.1", "url": "https://www.ensembl.org/id/ENSGALP00010026581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 107, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7L5-1", "uniprot_ac": "A0A8V0Z7L5", "uniprot_id": "A0A8V0Z7L5_CHICK", "mass": { "chemical_mass": 33312.0, "monoisotopic_mass": 33312.0 }, "refseq": { "ac": "XP_004943927", "name": "lysM and putative peptidoglycan-binding domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943927" }, "gene_names": [ { "name": "LYSMD4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5" } ] }, { "name": "LYSMD4", "type": "synonym", "evidence": [ { "id": "XP_004943927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943927" } ] } ], "protein_names": [ { "name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5/entry#names_and_taxonomy" } ] }, { "name": "lysM and putative peptidoglycan-binding domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "XP_004943927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943927" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943927.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYSMD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5", "locus": { "chromosome": "10", "start_pos": 17098972, "end_pos": 17112840, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018854", "url": "https://www.ensembl.org/id/ENSGALG00010018854" } ] } } ], "crossref": [ { "id": "A0A8V0Z7L5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7L5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427510", "url": "https://www.ncbi.nlm.nih.gov/gene/427510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427510", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ESYCVET", "url": "https://omabrowser.org/oma/group/ESYCVET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7L5", "url": "https://www.orthodb.org/?gene=A0A8V0Z7L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLNDSRPRPFQAPVTIHNYPGGQVYVFPNGRSDSEESSEEELNVMELRPRGREQQRCGPARGRAGDVVLLEREVTEDDSLNKLALQYGCKVADIKRVNNFIREQDLYALKSIKIPVKTHGLLTESSKELRPLPAACSQTGVTLVDVPEPDAGGSGSADSKQLVDYFRGIDKSIRDAVQAEVQLNAEYCVEAPERPLAEPGKRESSNGADCGIQWWNAVFIMLLVGIVLPVFYIIYFKTQENGPAAHTSNTTATSNVSTDGLEGKLLQSSVVGKNANGEMRPNTASPPSTHARKMVTLTRVQSGG", "length": 305, "header": "tr|A0A8V0Z7L5-1|A0A8V0Z7L5_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 4 OS=Gallus gallus OX=9031 GN=LYSMD4 PE=4 SV=1 CANONICAL=A0A8V0Z7L5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L5/entry#A0A8V0Z7L5-1", "sequence": { "sequence": "MRLNDSRPRPFQAPVTIHNYPGGQVYVFPNGRSDSEESSEEELNVMELRPRGREQQRCGPARGRAGDVVLLEREVTEDDSLNKLALQYGCKVADIKRVNNFIREQDLYALKSIKIPVKTHGLLTESSKELRPLPAACSQTGVTLVDVPEPDAGGSGSADSKQLVDYFRGIDKSIRDAVQAEVQLNAEYCVEAPERPLAEPGKRESSNGADCGIQWWNAVFIMLLVGIVLPVFYIIYFKTQENGPAAHTSNTTATSNVSTDGLEGKLLQSSVVGKNANGEMRPNTASPPSTHARKMVTLTRVQSGG", "length": 305, "header": "tr|A0A8V0Z7L5-1|A0A8V0Z7L5_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 4 OS=Gallus gallus OX=9031 GN=LYSMD4 PE=4 SV=1 CANONICAL=A0A8V0Z7L5-1" }, "locus": { "chromosome": "10", "start_pos": 17105581, "end_pos": 17100948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045535.1", "url": "https://www.ensembl.org/id/ENSGALT00010045535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027160.1", "url": "https://www.ensembl.org/id/ENSGALP00010027160.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H593-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "gene_name": "Lysmd4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRQKEVLAKTFQGPAVVCRTPNSHVYMFKNGSGDSGESSEEESHHVLRPRGKERQKNSIQQHPGAGNVVLLQRELAQEDSLNKLALQYGCKVADIKKVNNFLREQDLYALKSIKIPVRKHGILTETHQELTPLGGPSSETRVTLVELPEDEDATGAPAQSNQLMDFFKGIDENIERAVQSDVFHSDSCCVEAVDQPLLPTTQKPPADGADCGIQWWNAVFLMLLIGIVLPVFYLVYFKIQATGEASSSLNATVVPNGSMTLSPIPGQAPNLAIPVHTLPPSDSQVSSTTQVGA", "length": 293 }, "evidence": [ { "id": "A0A8V0Z7L5", "url": "https://omabrowser.org/oma/group/A0A8V0Z7L5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R4W5-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "gene_name": "Lysmd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGVPFQPLGNEKLRKEMRQKEVLAKTFQGPAVVCRTPNSHVYMFKNGSGDSGDSSEEESHQVVLRPRGKERQKNSSQPPGTGTMVLLQRELAQEDSLNKLALQYGCKVADIKKANNFIREQDLYALKSIKIPVRNHGILTETHQELMPLGASSSETRVTLVELPEDGDASGATAQGNQLTEFFKGIDENIERAVQSDVFHSDGCCVEAPDQPLLPITQKPAADGADCGIQWWNAVFLMLLIGIVLPVFYLVYFKIQATGETSDSLNTTVVPNGSMTLSPVPGQAPRLAVAVPTLPASDNQVSPTTEAGA", "length": 310 }, "evidence": [ { "id": "A0A8V0Z7L5", "url": "https://omabrowser.org/oma/group/A0A8V0Z7L5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG99-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "gene_name": "LYSMD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRHEELLTKTFQGPAVVCGTPTSHVYMFKNGSGDSGDSSEEESHRVVLRPRGKERHKSGVHQPPQAGAGDVVLLQRELAQEDSLNKLALQYGCKVADIKKVNNFIREQDLYALKSVKIPVRNHGILMETHKELKPLLSPSSETTVTVELPEADRAGAGTGAQAGQLMGFFKGIDQDIERAVQSEIFLHESYCMDTSHQPLLPAPPKTPMDGADCGIQWWNAVFIMLLIGIVLPVFYLVYFKIQASGETPNSLNTTVIPNGSMAMGTVPGQAPRLAVAVPAVTSADSQFSQTTQAGS", "length": 296 }, "evidence": [ { "id": "A0A8V0Z7L5", "url": "https://omabrowser.org/oma/group/A0A8V0Z7L5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CC84-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 4", "gene_name": "Lysmd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQKEVLAKSFQGPAAVCRTPNSHVYMFNNGSGDSGDSSEEESHQVVLRPRGKEHQKNSSQRPGAGTMVLLQRELAQEDSLNKLALQYGCKVADIKKANNFIREQDLYALKSIKIPVRNHGILTETHQELMPLGASSSETRVTLVDLPEDEDAGGATTQGNQLTDFFKGIDENIERAVHSDVFHGDSCCVEAPDQLLLPITQKPVADGADCGIQWWNAVFLMLLIGIVLPVFYLVYFKIQATGEPSNGLNATVVPNGSMTLSPVPGQAPRLAIPVPTLPASDSQVSPTTQAGA", 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}, { "id": "A0A8V0Z7N3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24324:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24324:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQYQAPGAAPAAALGVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAAPAPHSLPAPPPPTLPSPNSSFTSLVAPYRTPVYEPTPIHPAFSHHLAATYGTGAYAGPLYSFPRAVGDYTHALIRQDPLGKPLLWSPFIQRPLHKRKGGQVRFSNEQTIELEKKFETQKYLSPPERKRLAKLLQLSERQVKTWFQNRRAKWRRLKQENPQATKKEEAEGTGDHGDPRPEGSPSPAGGGEAEPQDSPSAASQEDPESDVSDDSDQEVDIEGDKGFYSATR", "length": 277, "header": "tr|A0A8V0Z7N3-1|A0A8V0Z7N3_CHICK Isoform 1 of Hematopoietically-expressed homeobox protein HHEX OS=Gallus gallus OX=9031 GN=HHEX PE=4 SV=1 CANONICAL=A0A8V0Z7N3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7N3/entry#A0A8V0Z7N3-1", "sequence": { "sequence": "MQYQAPGAAPAAALGVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAAPAPHSLPAPPPPTLPSPNSSFTSLVAPYRTPVYEPTPIHPAFSHHLAATYGTGAYAGPLYSFPRAVGDYTHALIRQDPLGKPLLWSPFIQRPLHKRKGGQVRFSNEQTIELEKKFETQKYLSPPERKRLAKLLQLSERQVKTWFQNRRAKWRRLKQENPQATKKEEAEGTGDHGDPRPEGSPSPAGGGEAEPQDSPSAASQEDPESDVSDDSDQEVDIEGDKGFYSATR", "length": 277, "header": "tr|A0A8V0Z7N3-1|A0A8V0Z7N3_CHICK Isoform 1 of Hematopoietically-expressed homeobox protein HHEX OS=Gallus gallus OX=9031 GN=HHEX PE=4 SV=1 CANONICAL=A0A8V0Z7N3-1" }, "locus": { "chromosome": "6", "start_pos": 21503910, "end_pos": 21500658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044673.1", "url": "https://www.ensembl.org/id/ENSGALT00010044673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026606.1", "url": "https://www.ensembl.org/id/ENSGALP00010026606.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of Hex during feather bud development.", "journal": "The International journal of developmental biology", "date": "2005", "authors": "Obinata Akiko, Akimoto Yoshihiro", "evidence": [ { "database": "RefSeq", "id": "NP_990583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990583" } ], "reference": [ { "type": "PubMed", "id": "16172986", "url": "https://glygen.org/publication/PubMed/16172986" } ] }, { "title": "Involvement of Hex in the initiation of feather morphogenesis.", "journal": "The International journal of developmental biology", "date": "2005", "authors": "Obinata Akiko, Akimoto Yoshihiro", "evidence": [ { "database": "RefSeq", "id": "NP_990583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990583" } ], "reference": [ { "type": "PubMed", "id": "16281172", "url": "https://glygen.org/publication/PubMed/16281172" } ] } ], "pathway": [ { "id": "gga:396182", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396182", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZN76-1", "protein_name": "Hematopoietically-expressed homeobox protein HHEX", "gene_name": "HHEX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/A0A8V0Z7N3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03014-1", "protein_name": "Hematopoietically-expressed homeobox protein HHEX", "gene_name": "HHEX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEVDIEGDKSYFNAG", "length": 270 }, "evidence": [ { "id": "A0A8V0Z7N3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7N3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV22-1", "protein_name": "Hematopoietically-expressed homeobox protein HHEX", "gene_name": "Hhex", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641470.1. 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MESECAWTKDQPVLSSQNMLHHFHRPSANQEAGRSLLTLAGSSSEAVEMAADFTRSFAMLCCLALWGSTCTCDATYTPPPHSTMNPGFPVPVNTNNPGVRKAARFGVYQFNNSSNDLFLFKEWQINKAMVQIVRGLKYMLHVEIGRTVCEKRGYSNLDDCHFQRKKNLQQILKCYFEVWMTPWLHKADVPVALCH", "length": 195, "header": "tr|A0A8V0Z7S0-1|A0A8V0Z7S0_CHICK Isoform 1 of Egg-white cystatin OS=Gallus gallus OX=9031 GN=CST7 PE=3 SV=1 CANONICAL=A0A8V0Z7S0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0/entry#A0A8V0Z7R5-1", "sequence": { "sequence": "MAADFTRSFAMLCCLALWGSTCTCDATYTPPPHSTMNPGFPVPVNTNNPGVRKAARFGVYQFNNSSNDLFLFKEWQINKAMVQIVRGLKYMLHVEIGRTVCEKRGYSNLDDCHFQRKKNLQQAGAEHRRMLFSPPTPWPTILGTPSRQLKFVIHSLSICRY", "length": 161, "header": "tr|A0A8V0Z7R5-1|A0A8V0Z7S0_CHICK Computationally mapped isoform of Egg-white cystatin OS=Gallus gallus OX=9031 GN=CST7 PE=3 SV=1 CANONICAL=A0A8V0Z7S0-1" }, "locus": { "chromosome": "3", "start_pos": 15517792, "end_pos": 15513509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045621.1", "url": "https://www.ensembl.org/id/ENSGALT00010045621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027205.1", "url": "https://www.ensembl.org/id/ENSGALP00010027205.1" } ] } }, { "isoform_ac": "A0A8V0Z7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0/entry#A0A8V0Z7S0-1", "sequence": { "sequence": "MESECAWTKDQPVLSSQNMLHHFHRPSANQEAGRSLLTLAGSSSEAVEMAADFTRSFAMLCCLALWGSTCTCDATYTPPPHSTMNPGFPVPVNTNNPGVRKAARFGVYQFNNSSNDLFLFKEWQINKAMVQIVRGLKYMLHVEIGRTVCEKRGYSNLDDCHFQRKKNLQQILKCYFEVWMTPWLHKADVPVALCH", "length": 195, "header": "tr|A0A8V0Z7S0-1|A0A8V0Z7S0_CHICK Isoform 1 of Egg-white cystatin OS=Gallus gallus OX=9031 GN=CST7 PE=3 SV=1 CANONICAL=A0A8V0Z7S0-1" }, "locus": { "chromosome": "3", "start_pos": 15517863, "end_pos": 15509014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045630.1", "url": "https://www.ensembl.org/id/ENSGALT00010045630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027210.1", "url": "https://www.ensembl.org/id/ENSGALP00010027210.1" } ] } }, { "isoform_ac": "A0A8V0Z8A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0/entry#A0A8V0Z8A9-1", "sequence": { "sequence": "MEAGRSLLTLAGSSSEAVEMAADFTRSFAMLCCLALWGSTCTCDATYTPPPHSTMNPGFPVPVNTNNPGVRKAARFGVYQFNNSSNDLFLFKEWQINKAMVQIVRGLKYMLHVEIGRTVCEKRGYSNLDDCHFQRKKNLQQILKCYFEVWMTPWLHKADVPVALCH", "length": 166, "header": "tr|A0A8V0Z8A9-1|A0A8V0Z8A9_CHICK Computationally mapped isoform of Egg-white cystatin OS=Gallus gallus OX=9031 GN=CST7 PE=3 SV=1 CANONICAL=A0A8V0Z7S0-1" }, "locus": { "chromosome": "3", "start_pos": 15517863, "end_pos": 15512660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045625.1", "url": "https://www.ensembl.org/id/ENSGALT00010045625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027207.1", "url": "https://www.ensembl.org/id/ENSGALP00010027207.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "negative regulation of microglial cell activation", "id": "GO:1903979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "lysosomal protein catabolic process", "id": "GO:1905146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "positive regulation of myelination", "id": "GO:0031643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "protease binding", "id": "GO:0002020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7S0", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8B4-1", "uniprot_ac": "A0A8V0Z8B4", "uniprot_id": "A0A8V0Z8B4_CHICK", "mass": { "chemical_mass": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045639.1", "url": "https://www.ensembl.org/id/ENSGALT00010045639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027215.1", "url": "https://www.ensembl.org/id/ENSGALP00010027215.1" } ] } }, { "isoform_ac": "A0A8V0Z8B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B4/entry#A0A8V0Z8B4-1", "sequence": { "sequence": "MSAAENGPRKELASGKHALVCCCCCRCFSFPSKRRTRRRPGVLPLRSVPEDAVLGVVEGLPAEELLWLGAVRSRLKYLVDGHAAVWAWARFEDVWPAAKPLEVLASSPPGISITNFSRSSSSEASAFPASVRLSCCVSSAACEHWNGGLETSGCASRKQFQTWGKQGREQLVCDVSSWRCAFSKPAVR", "length": 188, "header": "tr|A0A8V0Z8B4-1|A0A8V0Z8B4_CHICK Isoform 1 of F-box domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106812 PE=4 SV=1 CANONICAL=A0A8V0Z8B4-1" }, "locus": { "chromosome": "14", "start_pos": 13656044, "end_pos": 13642984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045635.1", "url": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7T5-1", "uniprot_ac": "A0A8V0Z7T5", "uniprot_id": "A0A8V0Z7T5_CHICK", "mass": { "chemical_mass": 88732.0, "monoisotopic_mass": 88732.0 }, "refseq": {}, "gene_names": [ { "name": "TBL3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ] } ], "protein_names": [ { "name": "Transducin beta like 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7T5", "database": "UniProtKB", "url": 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"MLCRGESSRSIKEDECSRDGKFMFCPCGTKLNVIDVETGSLLHSLEQDDQEDITSFVLSPDDEVLVTGSRALLLKQWNWRENRCVRTWKAVHIAPVATMVFDSTSTLLATGGCDSTIKIWDMIKQYCTHNLKGSSGVVHLVEFHPDISRLQLFSSSMDYKIRIWDLNSSKCVAVLDGHFSAVTSLAFTADGNTLISSGRDKICMVWNLKTRESIRTIPIYESVEAAVLLPEQGDFSQLGVKKQGLHFLTAGSKGVLKVWEVATAACVYSQPVPFEPVESEEEASEHSLTHCMLVPERNEIVTVSVEHNIVFYDAQTLQLRKQLAGYNDEVLDVKFLGPGDSHIVVATNSPQLKVFELSTSHCQILYGHTETILALDVFRKGLMFVSCAKDKSIRVWRMNKDGRVVCVAQGLGHAHGVGAVSCSRLKESFVVTSSQDCTIKVWNIPESLTSKAKAALISGPETLHAQMTERGHDKDINSVAVSPNDKLIATGSQDRLAKLWSCPDCSLLGVFTGHKRGIWCVQFSPVDQILATSSADGTLKLWGLQDFSCLKTFEGHDASVLKIIFVSRGTQLLSGGSDGLLKLWTIKTNECVKTLDGHEDKIWGLHTNKQDDMVVTASSDSSITLWKDVTEIEQEEAQAKREEQIMKEQELSNLLHEKRYLKALGLAISLDRPHTVLTVIKAILKESDGRKRLEENIARLRKDQKEAVLTFLVTWNTNSRNCHEAQAVIETLLKHEAPDNLLQYSGIKSAVESLLPYTERHFQRLSRLLQASMFIDFMWQNMKLSDVSQQEDMIL", "length": 795, "header": "tr|A0A8V0Z7T5-1|A0A8V0Z7T5_CHICK Isoform 1 of Transducin beta like 3 OS=Gallus gallus OX=9031 GN=TBL3 PE=1 SV=1 CANONICAL=A0A8V0Z7T5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5/entry#A0A8V0Z7T5-1", "sequence": { "sequence": "MLCRGESSRSIKEDECSRDGKFMFCPCGTKLNVIDVETGSLLHSLEQDDQEDITSFVLSPDDEVLVTGSRALLLKQWNWRENRCVRTWKAVHIAPVATMVFDSTSTLLATGGCDSTIKIWDMIKQYCTHNLKGSSGVVHLVEFHPDISRLQLFSSSMDYKIRIWDLNSSKCVAVLDGHFSAVTSLAFTADGNTLISSGRDKICMVWNLKTRESIRTIPIYESVEAAVLLPEQGDFSQLGVKKQGLHFLTAGSKGVLKVWEVATAACVYSQPVPFEPVESEEEASEHSLTHCMLVPERNEIVTVSVEHNIVFYDAQTLQLRKQLAGYNDEVLDVKFLGPGDSHIVVATNSPQLKVFELSTSHCQILYGHTETILALDVFRKGLMFVSCAKDKSIRVWRMNKDGRVVCVAQGLGHAHGVGAVSCSRLKESFVVTSSQDCTIKVWNIPESLTSKAKAALISGPETLHAQMTERGHDKDINSVAVSPNDKLIATGSQDRLAKLWSCPDCSLLGVFTGHKRGIWCVQFSPVDQILATSSADGTLKLWGLQDFSCLKTFEGHDASVLKIIFVSRGTQLLSGGSDGLLKLWTIKTNECVKTLDGHEDKIWGLHTNKQDDMVVTASSDSSITLWKDVTEIEQEEAQAKREEQIMKEQELSNLLHEKRYLKALGLAISLDRPHTVLTVIKAILKESDGRKRLEENIARLRKDQKEAVLTFLVTWNTNSRNCHEAQAVIETLLKHEAPDNLLQYSGIKSAVESLLPYTERHFQRLSRLLQASMFIDFMWQNMKLSDVSQQEDMIL", "length": 795, "header": "tr|A0A8V0Z7T5-1|A0A8V0Z7T5_CHICK Isoform 1 of Transducin beta like 3 OS=Gallus gallus OX=9031 GN=TBL3 PE=1 SV=1 CANONICAL=A0A8V0Z7T5-1" }, "locus": { "chromosome": "14", "start_pos": 6159035, "end_pos": 6149598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045661.1", "url": "https://www.ensembl.org/id/ENSGALT00010045661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027225.1", "url": "https://www.ensembl.org/id/ENSGALP00010027225.1" } ] } }, { "isoform_ac": "A0A8V0ZF73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5/entry#A0A8V0ZF73-1", "sequence": { "sequence": "MAATAAGSVVRFKSNYAVSRRIEPFYKGGRVQVSRDGKFMFCPCGTKLNVIDVETGSLLHSLEQDDQEDITSFVLSPDDEVLVTGSRALLLKQWNWRENRCVRTWKAVHIAPVATMVFDSTSTLLATGGCDSTIKIWDMIKQYCTHNLKGSSGVVHLVEFHPDISRLQLFSSSMDYKIRIWDLNSSKCVAVLDGHFSAVTSLAFTADGNTLISSGRDKICMVWNLKTRESIRTIPIYESVEAAVLLPEQGDFSQLGVKKQGLHFLTAGSKGVLKVWEVATAACVYSQPVPFEPVESEEEASEHSLTHCMLVPERNEIVTVSVEHNIVFYDAQTLQLRKQLAGYNDEVLDVKFLGPGDSHIVVATNSPQLKVFELSTSHCQILYGHTGDKSIRVWRMNKDGRVVCVAQGLGHAHGVGAVSCSRLKESFVVTSSQDCTIKVWNIPESLTSKAKAALISGPETLHAQMTERGHDKDINSVAVSPNDKLIATGSQDRLAKLWSCPDCSLLGVFTGHKRGIWCVQFSPVDQILATSSADGTLKLWGLQDFSCLKTFEGHDASVLKIIFVSRGTQLLSGGSDGLLKLWTIKTNECVKTLDGHEDKIWGLHTNKQDDMVVTASSDSSITLWKDVTEIEQEEAQAKREEQIMKEQELSNLLHEKRYLKALGLAISLDRPHTVLTVIKAILKESDGRKRLEENIARLRKDQKEAVLTFLVTWNTNSRNCHEAQAVIETLLKHEAPDNLLQYSGIKSAVESLLPYTERHFQRLSRLLQASMFIDFMWQNMKLSDVSQQEDMIL", "length": 793, "header": "tr|A0A8V0ZF73-1|A0A8V0ZF73_CHICK Computationally mapped isoform of Transducin beta like 3 OS=Gallus gallus OX=9031 GN=TBL3 PE=1 SV=1 CANONICAL=A0A8V0Z7T5-1" }, "locus": { "chromosome": "14", "start_pos": 6159035, "end_pos": 6149431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045650.1", "url": "https://www.ensembl.org/id/ENSGALT00010045650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027219.1", "url": "https://www.ensembl.org/id/ENSGALP00010027219.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7T5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13", "gene_name": "GNG13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEWDVPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEKGKCTIL", "length": 67 }, "evidence": [ { "id": "A0A8V0Z7U6", "url": "https://omabrowser.org/oma/group/A0A8V0Z7U6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7U6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7U6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", 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Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414847.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414847" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOXO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1", "locus": { "chromosome": "14", "start_pos": 6159594, "end_pos": 6170102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018902", "url": "https://www.ensembl.org/id/ENSGALG00010018902" } ] } } ], "crossref": [ { "id": "A0A8V0Z8E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06889", "url": 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"Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416546", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WERPEQS", "url": "https://omabrowser.org/oma/group/WERPEQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7V2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8E1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8E1", "database": 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"MSRFPVDVKAVGLMQCRKQKKYMMFVSWSDQNNILIYRTLEEFKRFHKELKRKFPIESGSLRRSDRTIPRFKDINGKQKKSGKINRSLERLKLLETYSQELLKVDAKISQSEDVIQFFKAQTQDLDPCFPEDSVVIMPSEIGGEKKKEVQQQQLSITYPQVSQSYRCIETFETKDTKNKTFKVAKKEIVEVLLKDMTGWWLVENADKQIAWFPASYLEQISAHKDIQNVESSDEEGSLYFVMRAYEAQKADELSLNKGVVVEVVRRSDNGWWLIRYNGRKGYMPSMCLQAYKNPHHRLQTIMNSGLHISTPNLCSPSPALQPLRDSTARDCTSGDGSDEDVSSSRSRSQSLPRVISTPDLESDSSSLSSGSAPSGVLSWKSDLSRSLPEVEQAVSPVLGRASATHSSKSPRLTYKDRNDSGFVEPSAADLSSLADPEVPTGAPKVPMRPSAHEILQRCSTVTKRAVQQSAACPPLQALHPLPSAH", "length": 485, "header": "tr|A0A8V0Z8E1-1|A0A8V0Z8E1_CHICK Isoform 1 of NADPH oxidase organizer 1 OS=Gallus gallus OX=9031 GN=NOXO1 PE=4 SV=1 CANONICAL=A0A8V0Z8E1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1/entry#A0A8V0Z7V2-1", "sequence": { "sequence": "MCIWKYMMFVSWSDQNNILIYRTLEEFKRFHKELKRKFPIESGSLRRSDRTIPRFKDINGKQKKSGKINRSLERLKLLETYSQELLKVDAKISQSEDVIQFFKAQTQDLDPCFPEDSVVIMPSEIGGEKKKEVQQQQLSITYPQVSQSYRCIETFETKDTKNKTFKVAKKEIVEVLLKDMTGWWLVENADKQIAWFPASYLEQISAHKDIQNVESSDEEGSLYFVMRAYEAQKADELSLNKGVVVEVVRRSDNGWWLIRYNGRKGYMPSMCLQAYKNPHHRLQTIMNSGLHISTPNLCSPSPALQPLRDSTARDCTSGDGSDEDVSSSRSRSQSLPRVISTPDLESDSSSLSSGSAPSGVLSWKSDLSRSLPEVEQAVSPVLGRASATHSSKSPRLTYKDRNDSGFVEPSAADLSSLADPEVPTGAPKVPMRPSAHEILQRCSTVTKRAVQQSAACPPLQALHPLPSAH", "length": 469, "header": "tr|A0A8V0Z7V2-1|A0A8V0Z8E1_CHICK Computationally mapped isoform of NADPH oxidase organizer 1 OS=Gallus gallus OX=9031 GN=NOXO1 PE=4 SV=1 CANONICAL=A0A8V0Z8E1-1" }, "locus": { "chromosome": "14", "start_pos": 6169867, "end_pos": 6160445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045697.1", "url": "https://www.ensembl.org/id/ENSGALT00010045697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027242.1", "url": "https://www.ensembl.org/id/ENSGALP00010027242.1" } ] } }, { "isoform_ac": "A0A8V0Z8E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1/entry#A0A8V0Z8E1-1", "sequence": { "sequence": "MSRFPVDVKAVGLMQCRKQKKYMMFVSWSDQNNILIYRTLEEFKRFHKELKRKFPIESGSLRRSDRTIPRFKDINGKQKKSGKINRSLERLKLLETYSQELLKVDAKISQSEDVIQFFKAQTQDLDPCFPEDSVVIMPSEIGGEKKKEVQQQQLSITYPQVSQSYRCIETFETKDTKNKTFKVAKKEIVEVLLKDMTGWWLVENADKQIAWFPASYLEQISAHKDIQNVESSDEEGSLYFVMRAYEAQKADELSLNKGVVVEVVRRSDNGWWLIRYNGRKGYMPSMCLQAYKNPHHRLQTIMNSGLHISTPNLCSPSPALQPLRDSTARDCTSGDGSDEDVSSSRSRSQSLPRVISTPDLESDSSSLSSGSAPSGVLSWKSDLSRSLPEVEQAVSPVLGRASATHSSKSPRLTYKDRNDSGFVEPSAADLSSLADPEVPTGAPKVPMRPSAHEILQRCSTVTKRAVQQSAACPPLQALHPLPSAH", "length": 485, "header": "tr|A0A8V0Z8E1-1|A0A8V0Z8E1_CHICK Isoform 1 of NADPH oxidase organizer 1 OS=Gallus gallus OX=9031 GN=NOXO1 PE=4 SV=1 CANONICAL=A0A8V0Z8E1-1" }, "locus": { "chromosome": "14", "start_pos": 6163751, "end_pos": 6160445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045693.1", "url": "https://www.ensembl.org/id/ENSGALT00010045693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027239.1", "url": "https://www.ensembl.org/id/ENSGALP00010027239.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416546", "resource": "KEGG Pathway" }, { "id": "R-GGA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1" } ], "pmid": "" }, { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { 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222, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 440 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7V3-1", "uniprot_ac": "A0A8V0Z7V3", "uniprot_id": "A0A8V0Z7V3_CHICK", "mass": { "chemical_mass": 38874.0, "monoisotopic_mass": 38874.0 }, "refseq": {}, "gene_names": [ { "name": "EEF2KMT", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ] } ], "protein_names": [ { "name": "Eukaryotic elongation factor 2 lysine methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EEF2KMT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3", "locus": { "chromosome": "14", "start_pos": 13401862, "end_pos": 13406822, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018736", "url": "https://www.ensembl.org/id/ENSGALG00010018736" } ] } } ], "crossref": [ { "id": "A0A8V0Z7V3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7V3", "database": "AlphaFoldDB", "categories": [] }, { "id": "416392", "url": "https://www.ncbi.nlm.nih.gov/gene/416392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416392", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416392", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIRTYRI", "url": "https://omabrowser.org/oma/group/PIRTYRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7V3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8U1", "url": "https://www.orthodb.org/?gene=A0A8V0Z8U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LGTGEVSPAPQSTHRDVVLHVVVEEPGRDQHPQQEEAAALELEQQLRAAPERSQSSLLADILHQTVLHPLCVRYPPSAAYRRCFLTELIKKHESTAADPLDELYDALARILNEEESAHCYKSYLLPSGEPVTLSESVAIISQGTTGLITWDAALQLAEWATENPAVFTNRTVLELGSGVGFTGLVICKTCNPKTYIFSDYHHCVLKQLTENIHLNGFTLEPETTNPAQGQEAEGKEYQQPKLVVAELDWGSVTEEQLLALQADVVIAADVIYDPEITLSLTGMLQKFSTSRADRKPEVYIALTVRNLDTYHMFQAELDKAGIRWQIIPAHSNSIFLHDTQPNVTILQLFI", "length": 350, "header": "tr|A0A8V0Z7V3-1|A0A8V0Z7V3_CHICK Isoform 1 of Eukaryotic elongation factor 2 lysine methyltransferase OS=Gallus gallus OX=9031 GN=EEF2KMT PE=3 SV=1 CANONICAL=A0A8V0Z7V3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3/entry#A0A8V0Z7V3-1", "sequence": { "sequence": "LGTGEVSPAPQSTHRDVVLHVVVEEPGRDQHPQQEEAAALELEQQLRAAPERSQSSLLADILHQTVLHPLCVRYPPSAAYRRCFLTELIKKHESTAADPLDELYDALARILNEEESAHCYKSYLLPSGEPVTLSESVAIISQGTTGLITWDAALQLAEWATENPAVFTNRTVLELGSGVGFTGLVICKTCNPKTYIFSDYHHCVLKQLTENIHLNGFTLEPETTNPAQGQEAEGKEYQQPKLVVAELDWGSVTEEQLLALQADVVIAADVIYDPEITLSLTGMLQKFSTSRADRKPEVYIALTVRNLDTYHMFQAELDKAGIRWQIIPAHSNSIFLHDTQPNVTILQLFI", "length": 350, "header": "tr|A0A8V0Z7V3-1|A0A8V0Z7V3_CHICK Isoform 1 of Eukaryotic elongation factor 2 lysine methyltransferase OS=Gallus gallus OX=9031 GN=EEF2KMT PE=3 SV=1 CANONICAL=A0A8V0Z7V3-1" }, "locus": { "chromosome": "14", "start_pos": 13406820, "end_pos": 13402269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045290.1", "url": "https://www.ensembl.org/id/ENSGALT00010045290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027037.1", "url": "https://www.ensembl.org/id/ENSGALP00010027037.1" } ] } }, { "isoform_ac": "A0A8V0Z8U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3/entry#A0A8V0Z8U1-1", "sequence": { "sequence": "MAGPGPELGLLFQRRFLAARQLRGMPWAELEQQLRAAPERSQSSLLADILHQTVLHPLCVRYPPSAAYRRCFLTELIKKHESTAADPLDELYDALARILNEEESAHCYKSYLLPSGEPVTLSESVAIISQGTTGLITWDAALQLAEWATENPAVFTNRTVLELGSGVGFTGLVICKTCNPKTYIFSDYHHCVLKQLTENIHLNGFTLEPETTNPAQGQEAEGKEYQQPKLVVAELDWGSVTEEQLLALQADVVIAADVIYDPEITLSLTGMLQKFSTSRADRKPEVYIALTVRNLDTYHMFQAELDKAGIRWQIIPAHSNSIFLHDTQPNVTILQLFI", "length": 338, "header": "tr|A0A8V0Z8U1-1|A0A8V0Z8U1_CHICK Computationally mapped isoform of Eukaryotic elongation factor 2 lysine methyltransferase OS=Gallus gallus OX=9031 GN=EEF2KMT PE=3 SV=1 CANONICAL=A0A8V0Z7V3-1" }, "locus": { "chromosome": "14", "start_pos": 13406141, "end_pos": 13402269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045284.1", "url": "https://www.ensembl.org/id/ENSGALT00010045284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027036.1", "url": "https://www.ensembl.org/id/ENSGALP00010027036.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416392", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JY15-1", "protein_name": "Eukaryotic elongation factor 2 lysine methyltransferase", "gene_name": "EEF2KMT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPEETADAARLLWSFERRFLAARALRSFPWQSLEEKLRDSSGSELLLDILQKTVHHPLCMRHPPPVKYARSFLSELIRKHEAVHTEPLDELYEALAKVLTAEESTRCHRSYLLPSGDAVTLAESLAIISHGTTGLVTWNAALYLAEWALEHPAAFAHRTVLELGSGAGLTGLAICKTCRPRAFVFSDCHSLVLEQLRGNILLNGFSLEPSVSTPSEPPGHDTPQAESPRVTVARLDWDVVTVPQLAALQPDIVIAADVLYCPETLLSLVGVLQKLSACRKDQRAPDAYVAFTVRNPETYQLFITELDQAGILWEVVPGHDQKLFPYEECSEMTILKLTL", "length": 340 }, "evidence": [ { "id": "A0A8V0Z7V3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7V3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z8P8-1", "protein_name": "Eukaryotic elongation factor 2 lysine methyltransferase", "gene_name": "Eef2kmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLREPSGSELLLAILQKTVKHPVCVQHGPSLKYSRCFLSKLIKKHEAVPMEPLDALYEALAEVLMARESTQCHRSYLLPSGDSVTLSESTAIVSHGTTGLVTWDAALYLAEWAIENPAAFTDRTILELGSGAGLTGLAICKACYPRAYVFSDCHAQVLEQLRRNVLLNGFSLELHTPIDSGSPKVTVAQLDWDEVTSSQLSAFQADTVIAADVLYCGEVTLSLVRVLRMLTDCQRKKAPDVYVAYTIRSQDTGKLFITELDRAGIHWEEVAPHTGKLFPYEEHSAIVILKLTLTGRHGV", "length": 335 }, "evidence": [ { "id": "A0A8V0Z7V3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7V3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1JPJ9-1", "protein_name": "Protein-lysine N-methyltransferase EEF2KMT", "gene_name": "EEF2KMT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPEERADAARLLRGFERRFLAARALRSFPWQSLEEKLRDSSGSELLLDILQKTVKHPLCVKHPPSVKYSRSFLSELIRKHEAVHTEPLDELYQALAEVLTAEDPTHCHRSYLLPSGDSVTLCESTAIVSHGTTGLVTWNAALYLAEWAVENPAVFAHRMVLELGSGAGLTGLAICKTCRPRAYIFSDCHSHVLEQLRGNVLLNGFSLEPSIDTWAQHPGPHTPEAERPWVTVARLDWDTVTAPQLAAFQPDVVLAADVLYCPETVLSLVGVLRKLSTCRKDQRAPDAYIAFTVRNPETCQLFTTELGQAGIPWEEVPCHDQKLFPYEEHSEMAILKLTL", "length": 340 }, "evidence": [ { "id": "A0A8V0Z7V3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7V3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UZW7-1", "protein_name": "Protein-lysine N-methyltransferase EEF2KMT", "gene_name": "Eef2kmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPEDHEGATSLLQSFERRFLAARALPSFPWQSLEEKLKDPSGSELLLAILQRTVKHPVCVQHGPSVKYARCFLSKLIKKHEAVPTEPLDALYEALAEVLMTQESTQCHRSYLLPSGNSVTLSESTAIVSHGTTGLVTWDAALYLAEWAIENPAAFTDRTILELGSGAGLTGLAICKACCPRAYIFSDCHAQVLEQLRGNVLLNGFSLEPHTPIDAGSSKVTVAQLDWDEVTASQLSAFQADVVIAADVLYCWEMTLSLVRVLKMLEDCQRKSAPDVYVAYTIRSQDTGKLFIEELDRAGIYWEEVPPHTGKLFPYEEHSAIVILKLVLTSRHGV", "length": 335 }, "evidence": [ { "id": "A0A8V0Z7V3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7V3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G04-1", "protein_name": "Protein-lysine N-methyltransferase EEF2KMT", "gene_name": "EEF2KMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPEENAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVHTEPLDELYEALAETLMAKESTQGHRSYLLPSGGSVTLSESTAIISYGTTGLVTWDAALYLAEWAIENPAVFTNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEADITAKLDSPRVTVAQLDWDVATVHQLSAFQPDVVIAADVLYCPEAIMSLVGVLRRLAACREHQRAPEVYVAFTVRNPETCQLFTTELGRAGIRWEVEPRHEQKLFPYEEHLEMAMLNLTL", "length": 330 }, "evidence": [ { "id": "A0A8V0Z7V3", "url": "https://omabrowser.org/oma/group/A0A8V0Z7V3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V3" }, { "id": "PF14904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM86 N-terminal", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 110, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7X1-1", "uniprot_ac": "A0A8V0Z7X1", "uniprot_id": "A0A8V0Z7X1_CHICK", "mass": { "chemical_mass": 185842.0, "monoisotopic_mass": 185842.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1", "locus": {} } ], "crossref": [ { "id": "cd04037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GATTVPLRCLAEDPGLPLDLGQLPLRDPQGHPTGATISLRCSYVPPGQVAAGNATSQRSEGMAPSLSPPRPTPVRVRVLEGHQLQGSAIKPVVTVLIGEQRFRSRIRAGNNPYYNEVAGGLFGFSGGDFLLLQRLLPRRHRLGLCAVFYSATMLSPMSEPLRFELSIGNHGDTGDTTCHPAASATPQGHPLFDGNRYYYMPWHDSKPVVAVTSTWEDAGQRWDGQNLLHSVGERLHPHVLSPGPPCPCCRPSTPKHGWTRSCAPPACTSCSTSPRPPPPGLRARPGPRCSLRPRPGWAAWPRCRPRCGESPILRAFFWLLDVPPSIPSCSAPSRRPACPTCCCGCGAVPAAWPAPRVPAHRLACSPHGPAACGRLCGRTHTLLLGVGRRAAPGAPPCPLSASSTPPPYPVRYENQMKILGKWSGRTLPGHPSFSDVAGRAGLPRERIRPPKGWRWDGPWAVEPPRRLLPAPEAGMDEVLEEVYENQSRQRGGEWGPAAVPSTDVAGTAVPPKEEVACPQGWHVTDDWRVEVTGAVDEAGWEYGVSVEAGDPSTAWHPKEEMYHTQRRRRWLRTRRRDSGAQGWEQDWHRWSGKEGVWEYASLWGGRFHPRRRAGDVCRRRCWHRLMVPELSSSVAAIFLLEGTSASRWQQHPKAEDTLSTPCLSSSAPSRVSHRVLGEDLGVQGSPTLTLTQDPLTSLPPPAEPSSFQLRCYLFQALELKPHGTRTTADPVAHVSFVHVSQSTRVLPGTLDPVWDQALLFHRVPLYGDPRVQWGFLGRSVCTPKVWLDVGRQKPPRLQRYPLEGPGGPAGELLAAFELLHEAEVRGGWQGGAWGLPEPVPSIHVPGTFSIPPGIRPVLRLMALEVLAWGLRGLRGRSLLPVRAPSLEVQCGGQILRIPPITNLATNPNFPINAFLLTLHLPVEEEYVPPIRLRVLDTQGFGYRPHVGQACVQDLARFRREPDGEEQLPRPRVPVPGPNPGTTLVILPHPAAPQDTEREEEDEEEGDWWSKFYMAMGDTAKSHRRTHRDSLKVYGCELEAVPQFEGLQDFCQTFPLYQPGGHQGDDPVPVGEFKGLFCLYPLPEDPGVPPPPRHFQELPPSQPQQCLVRVYIVRALDLSPRDRNGMCDPYVRVSLGSKTLGQRDQYVPNTVEPVFGRMFEVMGTVPLEKDLRVSLLDHDLLPPDQEIGSTTIDLENRLLSRFRAHCGLPPLYRTAGPGRWRDQLSPSRALEHLAHTRGLQAPEFSAEGTAVTFGGSTFLLSHFERGPPTYRHPGAPRERLALHVLRAWNLVPEHLETRTLYNSAQPGLEQGKVQMWVDIFPASLGPPGPPVDITPRQPQSYELRCVVWNTRDVEPGDINAAGQRMSDIYVTGWLDGLEEQKQRTDVHYRALQGDGSFHWRFVFPFQYLAAERRCVLPQKEHFWSLDETVLKVPPKLILQVWDNDKFSADDFLGVLELELTRLPRPAQRPQDCALKPRLSPWPWGRIGGPPHFSLFRQKQARGWWPCVVHEGGTRRMAGKLELSLELLSEKEAEERPAGKGREEPNAYPTLQPPVRPDSSFLWLRAPLRALRYAVWQRHRCRITVTLALLLLLLLLLNFIYSAPVSTEDPQTPSPAAHRALTHKQSAAIQLCSELLGSHRPPGPGGTPCHHPPPPKSMRVAAGTQCSPRGESGRAAPSP", "length": 1677, "header": "tr|A0A8V0Z7X1-1|A0A8V0Z7X1_CHICK Isoform 1 of C2 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1/entry#A0A8V0Z7V5-1", "sequence": { "sequence": "MLQDTMVAYRGRVLLELSTHTGDSDGRQQDSIRLLPRRHRLGLCAVFYSATMLSPMSEPLRFELSIGNHGDTGDTTCHPAASATPQGHPLFDGNRYYYMPWHDSKPVVAVTSTWEDAGQRWDGQNLLHSVGERLVILSISLPCPPRVTPTSTPYDLHVPSMSHLCHLHDPSIPFPQTFYISMSLLCPISTSSPYFLHVLHMSHLCHLHVLSCPLHISSCPLRPLSISCPLNPPPHPLNVSLPPPYLPMSPLCPHPPHSLCAPLMSPHVPRCPQAPGHLHAQLRVRLWLGRVAESQELPRYLEGPLHVYAEMYENQMKILGKWSGRTLPGHPSFSDVAGRAGLPRERIRPPKGWRWDGPWAVEPPRRLLPAPEAGMDEVLEEVYENQSRQRGGEWGPAAVPSTDVAGTAVPPKEEVACPQGWHVTDDWRVEVTGAVDEAGWEYGVSVEAGDPSTAWHPKEEMYHTQRRRRWLRTRRRDSGAQGWEQDADVAHSPEAPDKVWEYASLWGGRFHPRRRAGDVCRRRCWHRLMVPELSSSVAAIFLLEGTAVRMGVDGGTEGWGSFQLRCYLFQALELKPHAGAAPTDPVAHVSFVHVSQSTRVLPGTLDPVWDQALLFHRVPLYGDPRGVRDEPPAVVVEVTYRQWAPMEGGHPCSAAPPRLQRYPLEGPGGPAGELLAAFELLHEAEVRGGWQGGAWGLPEPDGAVARLSTPPWRQGTFSIPPGIRPVLRLMALEVLAWGLRGLRGRSLLPVRAPSLEVQCGGQILRIPPITNLATNPNFPINAFLLTLHLPVEEEYVPPIRLRVLDTQGFGYRPHVGQACVQDLARFRREPDGEEQLPRPRVPVPGPNPGTTLSPPLLVPAPSLEEEDEEEGDWWSKFYMAMGDTAKSHRRTHRDSLKVYGCELEAVPQFEGLQDFCQTFPLYQPGGHQGDDPVPVGEFKGLFCLYPLPEDPGVPPPPRHFQELPPSQPQQCLVRVYIVRALDLSPRDRNGMCDPYVRVSLGSKTLGQRDQYVPNTVEPVFGRMFEVMGTVPLEKDLRVSLLDHDLLPPDQEIGSTTIDLENRLLSRFRAHCGLPPLYRTAGPGRWRDQLSPSRALEHLAHTRGLFGIAERGPPTYRHPGAPRERLALHVLRAWNLVPEHLETRTLYNSAQPGLEQGKVQMWVDIFPASLGPPGPPVDITPRQPQSYELRCVVWNTRDVEPGDINAAGQRMSDIYVTGWLDGLEEQKQRTDVHYRALQGDGSFHWRFVFPFQYLAAERRCVLPQKEHFWSLDETVLKVPPKLILQVWDNDKFSADDFLGVLELELTRLPRPAQRPQDCALKPRLSPWPWGRIGGPPHFSLFRQKQARGWWPCVVHEGGTRRMAGKLELSLELLSEKEAEERPAGKGREEPNAYPTLQPPVRPDSSFLWLRAPLRALRYAVWQRHRCRITVTLALLLLLLLLLNFIYSAPVTVALLRPHERNTARSH", "length": 1465, "header": "tr|A0A8V0Z7V5-1|A0A8V0Z7X1_CHICK Computationally mapped isoform of C2 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X1-1" }, "locus": { "chromosome": "22", "start_pos": 3010043, "end_pos": 2994545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049638.1", "url": "https://www.ensembl.org/id/ENSGALT00010049638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029324.1", "url": "https://www.ensembl.org/id/ENSGALP00010029324.1" } ] } }, { "isoform_ac": "A0A8V0Z7X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1/entry#A0A8V0Z7X1-1", "sequence": { "sequence": "GATTVPLRCLAEDPGLPLDLGQLPLRDPQGHPTGATISLRCSYVPPGQVAAGNATSQRSEGMAPSLSPPRPTPVRVRVLEGHQLQGSAIKPVVTVLIGEQRFRSRIRAGNNPYYNEVAGGLFGFSGGDFLLLQRLLPRRHRLGLCAVFYSATMLSPMSEPLRFELSIGNHGDTGDTTCHPAASATPQGHPLFDGNRYYYMPWHDSKPVVAVTSTWEDAGQRWDGQNLLHSVGERLHPHVLSPGPPCPCCRPSTPKHGWTRSCAPPACTSCSTSPRPPPPGLRARPGPRCSLRPRPGWAAWPRCRPRCGESPILRAFFWLLDVPPSIPSCSAPSRRPACPTCCCGCGAVPAAWPAPRVPAHRLACSPHGPAACGRLCGRTHTLLLGVGRRAAPGAPPCPLSASSTPPPYPVRYENQMKILGKWSGRTLPGHPSFSDVAGRAGLPRERIRPPKGWRWDGPWAVEPPRRLLPAPEAGMDEVLEEVYENQSRQRGGEWGPAAVPSTDVAGTAVPPKEEVACPQGWHVTDDWRVEVTGAVDEAGWEYGVSVEAGDPSTAWHPKEEMYHTQRRRRWLRTRRRDSGAQGWEQDWHRWSGKEGVWEYASLWGGRFHPRRRAGDVCRRRCWHRLMVPELSSSVAAIFLLEGTSASRWQQHPKAEDTLSTPCLSSSAPSRVSHRVLGEDLGVQGSPTLTLTQDPLTSLPPPAEPSSFQLRCYLFQALELKPHGTRTTADPVAHVSFVHVSQSTRVLPGTLDPVWDQALLFHRVPLYGDPRVQWGFLGRSVCTPKVWLDVGRQKPPRLQRYPLEGPGGPAGELLAAFELLHEAEVRGGWQGGAWGLPEPVPSIHVPGTFSIPPGIRPVLRLMALEVLAWGLRGLRGRSLLPVRAPSLEVQCGGQILRIPPITNLATNPNFPINAFLLTLHLPVEEEYVPPIRLRVLDTQGFGYRPHVGQACVQDLARFRREPDGEEQLPRPRVPVPGPNPGTTLVILPHPAAPQDTEREEEDEEEGDWWSKFYMAMGDTAKSHRRTHRDSLKVYGCELEAVPQFEGLQDFCQTFPLYQPGGHQGDDPVPVGEFKGLFCLYPLPEDPGVPPPPRHFQELPPSQPQQCLVRVYIVRALDLSPRDRNGMCDPYVRVSLGSKTLGQRDQYVPNTVEPVFGRMFEVMGTVPLEKDLRVSLLDHDLLPPDQEIGSTTIDLENRLLSRFRAHCGLPPLYRTAGPGRWRDQLSPSRALEHLAHTRGLQAPEFSAEGTAVTFGGSTFLLSHFERGPPTYRHPGAPRERLALHVLRAWNLVPEHLETRTLYNSAQPGLEQGKVQMWVDIFPASLGPPGPPVDITPRQPQSYELRCVVWNTRDVEPGDINAAGQRMSDIYVTGWLDGLEEQKQRTDVHYRALQGDGSFHWRFVFPFQYLAAERRCVLPQKEHFWSLDETVLKVPPKLILQVWDNDKFSADDFLGVLELELTRLPRPAQRPQDCALKPRLSPWPWGRIGGPPHFSLFRQKQARGWWPCVVHEGGTRRMAGKLELSLELLSEKEAEERPAGKGREEPNAYPTLQPPVRPDSSFLWLRAPLRALRYAVWQRHRCRITVTLALLLLLLLLLNFIYSAPVSTEDPQTPSPAAHRALTHKQSAAIQLCSELLGSHRPPGPGGTPCHHPPPPKSMRVAAGTQCSPRGESGRAAPSP", "length": 1677, "header": "tr|A0A8V0Z7X1-1|A0A8V0Z7X1_CHICK Isoform 1 of C2 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X1-1" }, "locus": { "chromosome": "22", "start_pos": 3012991, "end_pos": 2994570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049663.1", "url": "https://www.ensembl.org/id/ENSGALT00010049663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029339.1", "url": "https://www.ensembl.org/id/ENSGALP00010029339.1" } ] } }, { "isoform_ac": "A0A8V0ZEN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1/entry#A0A8V0ZEN3-1", "sequence": { "sequence": "MKKTKMGVQCGGQILRIPPITNLATNPNFPINAFLLTLHLPVEEEYVPPIRLRVLDTQGFGYRPHVGQACVQDLARFRREPDGEEQLPRPRVPVPGPNPGTTLSPPLLREEEDEEEGDWWSKFYMAMGDTAKSHRRTHRDSLKVYGCELEAVPQFEGLQDFCQTFPLYQPGGHQGDDPVPVGEFKGLFCLYPLPEDPGVPPPPRHFQELPPSQPQQCLVRVYIVRALDLSPRDRNGMCDPYVRVSLGSKTLGQRDQYVPNTVEPVFGRMFEVMGTVPLEKDLRVSLLDHDLLPPDQEIGSTTIDLENRLLSRFRAHCGLPPLYRTAGPGRWRDQLSPSRALEHLAHTRGLQAPEFSAEGTAVTFGGSTFLLSHFGPPTYRHPGAPRERLALHVLRAWNLVPEHLETRTLYNSAQPGLEQGKVQMWVDIFPASLGPPGPPVDITPRQPQSYELRCVVWNTRDVEPGDINAAGQRMSDIYVTGWLDGLEEQKQRTDVHYRALQGDGSFHWRFVFPFQYLAAERRCVLPQKEHFWSLDETVLKVPPKLILQVWDNDKFSADDFLGVLELELTRLPRPAQRPQDCALKPRLSPWPWGRIGGPPHFSLFRQKQARGWWPCVVHEGGTRRMAGKLELSLELLSEKEAEERPAGKGREEPNAYPTLQPPVRPDSSFLWLRAPLRALRYAVWQRHRCRITVTLALLLLLLLLLNFIYSAPVSTEDPQTPSPAAHRALLTSSHPQTSILPTRHRSPHTGTHPGSETQLLPCPTAPTSRALPSSCAQSC", "length": 779, "header": "tr|A0A8V0ZEN3-1|A0A8V0ZEN3_CHICK Computationally mapped isoform of C2 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X1-1" }, "locus": { "chromosome": "22", "start_pos": 3001765, "end_pos": 2994701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049610.1", "url": "https://www.ensembl.org/id/ENSGALT00010049610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029308.1", "url": "https://www.ensembl.org/id/ENSGALP00010029308.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1645, "start_aa": "Thr", "end_pos": 1645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1645", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 72, "start_aa": "Thr", "end_pos": 72, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" } ], "pmid": "" }, { "name": "membrane fusion", "id": "GO:0061025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" } ], "pmid": "" }, { "name": "T-tubule organization", "id": "GO:0033292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z7X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 690, "end_pos": 823, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 72, 1645 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 485, "end_pos": 487 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7V6-1", "uniprot_ac": "A0A8V0Z7V6", "uniprot_id": "A0A8V0Z7V6_CHICK", "mass": { "chemical_mass": 55427.0, "monoisotopic_mass": 55427.0 }, "refseq": {}, "gene_names": [ { "name": "ATG14", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ] } ], "protein_names": [ { "name": "Autophagy related 14", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6", "locus": { "chromosome": "5", "start_pos": 55795493, "end_pos": 55777458, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018501", "url": "https://www.ensembl.org/id/ENSGALG00010018501" } ] } } ], "crossref": [ { "id": "A0A8V0Z7V6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7V6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13664:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13664:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPSGCRPQPGGQGGGGIGAGPGVLRGAEEDAEGLYVAVERCPLCNTTRRRLTCAKCVQGGDFVFFDGRDSERFSDKKERLMHLKTKQREFQNHVLKAMEGKEITDQLRWKIMSCKMRIEQLKQTICKENDEMTRNTEGLLRIKEENQKHYRRAQRHQEKKEKIQRHNRKLGDLVEKKTYDLKTQHEHLANLRRTHILELTSVIFPIEEVKTSMRDPADVSSESDNAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWITLPNNGDYSAYYNWVEEKKTTQGPDMEHNNPAHTISAALCYATQLVNTLSLILDVNLPKKLCNRQFCGENLSRHRFTRAVKKLNANILHLCFSQHVNLDLLHPLHTLRNLMYLVSPDTENLGRSGPFEISADLEDSMEFVDPSATGETDESGDEHVSDEETDLGTDWENLPSPRFCDIPSQQVEMLQSQSTQVSQPIASSSAGGMISSAAASVTSWFKAYTGHR", "length": 492, "header": "tr|A0A8V0Z7V6-1|A0A8V0Z7V6_CHICK Isoform 1 of Autophagy related 14 OS=Gallus gallus OX=9031 GN=ATG14 PE=4 SV=1 CANONICAL=A0A8V0Z7V6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6/entry#A0A8V0Z7V6-1", "sequence": { "sequence": "MASPSGCRPQPGGQGGGGIGAGPGVLRGAEEDAEGLYVAVERCPLCNTTRRRLTCAKCVQGGDFVFFDGRDSERFSDKKERLMHLKTKQREFQNHVLKAMEGKEITDQLRWKIMSCKMRIEQLKQTICKENDEMTRNTEGLLRIKEENQKHYRRAQRHQEKKEKIQRHNRKLGDLVEKKTYDLKTQHEHLANLRRTHILELTSVIFPIEEVKTSMRDPADVSSESDNAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWITLPNNGDYSAYYNWVEEKKTTQGPDMEHNNPAHTISAALCYATQLVNTLSLILDVNLPKKLCNRQFCGENLSRHRFTRAVKKLNANILHLCFSQHVNLDLLHPLHTLRNLMYLVSPDTENLGRSGPFEISADLEDSMEFVDPSATGETDESGDEHVSDEETDLGTDWENLPSPRFCDIPSQQVEMLQSQSTQVSQPIASSSAGGMISSAAASVTSWFKAYTGHR", "length": 492, "header": "tr|A0A8V0Z7V6-1|A0A8V0Z7V6_CHICK Isoform 1 of Autophagy related 14 OS=Gallus gallus OX=9031 GN=ATG14 PE=4 SV=1 CANONICAL=A0A8V0Z7V6-1" }, "locus": { "chromosome": "5", "start_pos": 55793280, "end_pos": 55777498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044759.1", "url": "https://www.ensembl.org/id/ENSGALT00010044759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026681.1", "url": "https://www.ensembl.org/id/ENSGALP00010026681.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate biosynthetic process", "id": "GO:0036092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "post-transcriptional 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"https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7V6" } ], "pmid": "" }, { "name": "response to mitochondrial depolarisation", "id": "GO:0098780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098780", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V0Z7X2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z7X2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7X2", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z7X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEIAQRPRADGLRSARCAAQMCSQLGPAVPPGSVLRHAWTGHEAVCMGWEGTSMGSAPALLEAAGAAP", "length": 70, "header": "tr|A0A8V0Z7X2-1|A0A8V0Z7X2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X2/entry#A0A8V0Z7X2-1", "sequence": { "sequence": "MEAEIAQRPRADGLRSARCAAQMCSQLGPAVPPGSVLRHAWTGHEAVCMGWEGTSMGSAPALLEAAGAAP", "length": 70, "header": "tr|A0A8V0Z7X2-1|A0A8V0Z7X2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z7X2-1" }, "locus": { "chromosome": "4", "start_pos": 3721101, "end_pos": 3719844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041965.1", "url": "https://www.ensembl.org/id/ENSGALT00010041965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024562.1", "url": "https://www.ensembl.org/id/ENSGALP00010024562.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z7X7-1", "uniprot_ac": "A0A8V0Z7X7", "uniprot_id": "A0A8V0Z7X7_CHICK", "mass": { "chemical_mass": 45763.0, "monoisotopic_mass": 45763.0 }, "refseq": { "ac": "XP_424383", "name": "transcription factor IIIB 50 kDa subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424383" }, "gene_names": [ { "name": "BRF2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7" } ] }, { "name": "BRF2", "type": "synonym", "evidence": [ { "id": "XP_424383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424383" } ] } ], "protein_names": [ { "name": "Transcription factor IIIB 50 kDa subunit", "type": "recommended", "evidence": [ { "id": "A0A8V0Z7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7/entry#names_and_taxonomy" } ] }, { "name": "B-related factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7/entry#names_and_taxonomy" } ] }, { "name": "transcription factor IIIB 50 kDa subunit", "type": "synonym", "evidence": [ { "id": "XP_424383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424383" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_424383.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424383" } ] }, { "annotation": "General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7#function" }, { "database": "UniProtKB", "id": "ARBA00045875", "url": "https://www.uniprot.org/uniprotkb/ARBA00045875#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7", "locus": { "chromosome": "22", "start_pos": 2385188, "end_pos": 2389553, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017395", "url": "https://www.ensembl.org/id/ENSGALG00010017395" } ] } } ], "crossref": [ { "id": "A0A8V0Z7X7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z7X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20555", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20555", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426772", "url": "https://www.ncbi.nlm.nih.gov/gene/426772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426772", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426772", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLPHPAY", "url": "https://omabrowser.org/oma/group/DLPHPAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7X7", "url": "https://www.orthodb.org/?gene=A0A8V0Z7X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424383", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPSRCPECGSAALLEDAHYAQQQLVCAACGCVLAEGLLTTTYSDEGQLREVAYSQSTGQKEQLNRCEQRGIRRVQDLCKVLRLPSVFEGTAVSYFQRALQHPSFRLVSLEKKELLVGCCVLATCRQHNWPLTLGTICSLLYAKQELVTSVYLSLQKELGISVPALSLADLVKTHLNSFRLFQHTEDIPVPFVEDKEKMLARTMQVVELASETWLVTGRHPIPIVTAAAFLSWQSLQPSARLTCTFTQFCKAAGVDLPPPARLRLKELYDVLLRMAAELAWLKVLNLDKKTVVKHIGDLLQHRIFLLKNAFCAADAEEQQGAAQAEDSSSNPPAAAGTEPDKGHPLGGKQKAEGSRRPLLPPCLLHPRKRLRTAASSASDAAITGDAPISDSEIEQYLRGPEEIRAFRRAKVWQ", "length": 415, "header": "tr|A0A8V0Z7X7-1|A0A8V0Z7X7_CHICK Isoform 1 of Transcription factor IIIB 50 kDa subunit OS=Gallus gallus OX=9031 GN=BRF2 PE=3 SV=1 CANONICAL=A0A8V0Z7X7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X7/entry#A0A8V0Z7X7-1", "sequence": { "sequence": "MAAPSRCPECGSAALLEDAHYAQQQLVCAACGCVLAEGLLTTTYSDEGQLREVAYSQSTGQKEQLNRCEQRGIRRVQDLCKVLRLPSVFEGTAVSYFQRALQHPSFRLVSLEKKELLVGCCVLATCRQHNWPLTLGTICSLLYAKQELVTSVYLSLQKELGISVPALSLADLVKTHLNSFRLFQHTEDIPVPFVEDKEKMLARTMQVVELASETWLVTGRHPIPIVTAAAFLSWQSLQPSARLTCTFTQFCKAAGVDLPPPARLRLKELYDVLLRMAAELAWLKVLNLDKKTVVKHIGDLLQHRIFLLKNAFCAADAEEQQGAAQAEDSSSNPPAAAGTEPDKGHPLGGKQKAEGSRRPLLPPCLLHPRKRLRTAASSASDAAITGDAPISDSEIEQYLRGPEEIRAFRRAKVWQ", "length": 415, "header": "tr|A0A8V0Z7X7-1|A0A8V0Z7X7_CHICK Isoform 1 of Transcription factor IIIB 50 kDa subunit OS=Gallus gallus OX=9031 GN=BRF2 PE=3 SV=1 CANONICAL=A0A8V0Z7X7-1" }, "locus": { "chromosome": "22", "start_pos": 2389541, "end_pos": 2387148, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041974.1", "url": "https://www.ensembl.org/id/ENSGALT00010041974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024567.1", "url": "https://www.ensembl.org/id/ENSGALP00010024567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426772", "resource": "KEGG Pathway" }, { "id": "R-GGA-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0Y1N6-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "BRF2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGRGRCPDCGSTELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYQHSGIRAARLQKKEVLVGCCVLITCRQRNWPLTMGTICTLIYADLDVFSGTYMQMVKLLGLDVPSLCLADLVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTLQLVELADETWLVTGRHPLPVVTAATFLAWQSLQPSDRLTCSLARFCKLANVDLPYPAASRLQELLAVLLRMAGQLAWLQVLKLDKRSVVKHIGDLLQHRHTLVRKAFRDGTSETDEREKELPGQGQGKEEAGSSSVDLPEGKRPASPAPLLPPCMLKPPKRICPTPPVSTVTGDENISDSEIEQYLRTPQEVRDFQKAQAAGQATTSGPNPP", "length": 417 }, "evidence": [ { "id": "A0A8V0Z7X7", "url": "https://omabrowser.org/oma/group/A0A8V0Z7X7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H1G5-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "Brf2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFNDEGNLREVTYSRSTGENEQVSRSQQRDLRRVRDLCRILKLPPTFEDTAISYYQRAYQLPGIRDARLQKKEVLVGCCVLITCRQHNWPLTMGTICTLLYADLDVFSGTYMQLVKLLGLDVPALCLEELVKSYCSSFRLFQASSPIPAKYVEDKDKMLSRTLLLVELANETWLVTGRHPLPVITAATFLAWQSLRPSARLTCSLAQFCKLANVDLPYPAASRLQELLAVLLQMASQLAWLRVLKLDKRTVVKHIGDLLQHRHMLVRMAFRDGTAEAETQEQEQGEQGQQEEAEDRTFNLSKRKRPSSPAPLLPPCMLKPSKRTHPTPSISTVTGDEDISDSEIEQYLRTPQEVRDFQRAQAASQAAMSVPNPP", "length": 416 }, "evidence": [ { "id": "A0A8V0Z7X7", "url": "https://omabrowser.org/oma/group/A0A8V0Z7X7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q29S07-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "BRF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGRGRCPDCGSAELVEDSHYSQNQLVCSDCGCVVTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAHQLAGIRTARLQKKEVLAGCCVLITCRQRNWPLTMGTICTLLYADLDVFSGTYMQIVKLLGLDVPSLCLVDLVKTYCSSFKLFEASPSVPAKYVEDKEKMLSRTLQLVELADETWLVTGRHPLPVITAATFLAWQSLRPSDRLTCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLQVLKLDKRSVVKHIGDLLQHRHMLVRKAFRDGTAEMDAGEKELQGQGQGQGLGDEDVGSSSLELPAGKRPSSPALLLPPCMLKPPKRVCPAPPVSMVTGDEDISDSEIEQYLRTPQEVRDFQKAQAARQAAQGTPNPP", "length": 421 }, "evidence": [ { "id": "A0A8V0Z7X7", "url": "https://omabrowser.org/oma/group/A0A8V0Z7X7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UAW9-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "Brf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNFREVTYSRSTGENEQVSRCQQRDLRRVRDLCRILKLPLTFEDTAISYYQKAYQLSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGTICTLLYADLDLFSGTYMQMVKLLGLDVPSLCLADLVKSYCSSFKLFQASPSVPAKYVEDKDKMLSRTLLLVELADETWLVTGRHPLPIITAATFLAWQSLRPSDRLTCSLAQFCKLANVDLPYPAASRLQELLAVLLQMAGQLAWLQVLKLNKRSVVKHIGDLLQHRHMLVRTAFRDGTAEVETQQQQQQQQGQGQGQQDEVGDGPFDLPKRKRRASPTPLLPPCMLKPPKRTHTLPPESAVTGDEDISDSEIEQYLRTPQEVRDFERAQAASQAAMRVPNPP", "length": 420 }, "evidence": [ { "id": "A0A8V0Z7X7", "url": "https://omabrowser.org/oma/group/A0A8V0Z7X7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8D6-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "Brf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z855-1", "uniprot_ac": "A0A8V0Z855", "uniprot_id": "A0A8V0Z855_CHICK", "mass": { "chemical_mass": 275850.0, "monoisotopic_mass": 275850.0 }, "refseq": {}, "gene_names": [ { "name": "CACNA1H", "type": "recommended", "evidence": [ { "id": "A0A8V0Z855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ] } ], "protein_names": [ { "name": "Voltage-dependent T-type calcium channel subunit alpha-1H", "type": "recommended", "evidence": [ { "id": "A0A8V0Z855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855/entry#names_and_taxonomy" } ] }, { "name": "Voltage-gated calcium channel subunit alpha Cav3.2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons. In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z849", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z849#function" }, { "database": "UniProtKB", "id": "ARBA00055553", "url": "https://www.uniprot.org/uniprotkb/ARBA00055553#function" }, { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACNA1H", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855", "locus": { "chromosome": "14", "start_pos": 5243392, "end_pos": 5444039, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017430", "url": "https://www.ensembl.org/id/ENSGALG00010017430" } ] } } ], "crossref": [ { "id": "416526", "url": "https://www.ncbi.nlm.nih.gov/gene/416526", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQAWSCG", "url": "https://omabrowser.org/oma/group/GQAWSCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z849", "url": "https://www.orthodb.org/?gene=A0A8V0Z849", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z855", "url": "https://www.orthodb.org/?gene=A0A8V0Z855", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z849", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z849", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z849-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z849-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z855-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGESREPRPAGGEVRVPITVPPRRAAEQPLDDAGSAPSGSPSRDPPPDLASEEEEQVPYPALAPTAFFCLKQTTRPRSWCLRLVCNPWFEHVSMLVILLNCVTLGMFQPCEDVECQSERCTILEAFDDFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNRLDFFIVMAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDRNLATTYNLTFLHPYYRTDEAEENPFICSSHRENGMQKCSNIPTRKEYKVECTLSMDSYTPSLYNPDFSSKNACINWNQYYNVCMAGDVNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTIRLYNNWQSKRRKKVNPNNTTNGQSRRGKKRITSIHHLIHHHHHHHHHHYHISNGSPRGPRSNPEICDLELKVMKPGGQLMLPSPSPNLQSPVPPPDSESVHSIYHADCHVEGPQVNCKSSNAPASIKLTTGLSNHGNMNYPTILPSPTSKASSVPVPKGKKNGSSPVAVVNSPVTLGTDSYGKLQQLVGEHGLRRTPSRLSGLSVACPLPSPPGGTLSCELQDCPFCASLLEDPEFAFSESDSCDSDSNGIYEFTQDLRHGDHRDQLQQQRGRRKRKKKKPKERNKVTRLWKAFGSKLKRIVESKYFNRGIMIAILINTLSMGIEYHEQPDELTNALEISNIVFTSMFALEMLLKLLAFGLFGYIKNPYNIFDGIIVVISVWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSANFDDDFEKLKDLRATEMKMYSLAVTPNGHLEGRGSMPPPIIMRTAATPMPTPKCSPHMDSVHTFVDSRRGSNASLDPLTYDQKSSSSLRSSPCANWGTNSNWGSRRSSWNSLGRAPSLKKKNQSGERESLLSGEGKGSTDDDSDDAKSSTVSRPSLHRRAESLDYRSSLDLPELLQLPPMRHSLSISPMAVLPAEYQDCNGKMVHVPSEFFLHIDGHKEEAVDYEDDMEDSYCYRIRKVLEPYKPEWCKSHEDWSLYLFSPQNRFRVMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPHSTERIFLSVSNYIFTAIFVAEMMVKVVALGFFSGENTYLQSSWNVLDGVLVFVSIIDIIVSMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCDGPDVKNITTKTDCTNAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPIQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRRPYYADYSPARKYIHTLCTSHYLDLFITFIIGVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAVLKLVAFGFRRFFKDRWNQLDLAIVLLSIVGITLEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCSEENPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIELEMSRGASTTSGSRGGAVALESRASCRSQEAMKSEPAAQAKHQALEALSCENVSVAIPDTLEGAETPMMEILSFCSVSHHVLTPSHHPRGREAEGGTAIPQPQDSQNMLTVRKISVSRMHSLPNDSYMFRPVMPAKAPFPLHEVEMEAYPCKSQRGSITSIRSQPVGTCSSLRVPPESLHVAVRSPGREGWHRWKVLPPHVVPRSPTLSKLLCRQEAVRTDSVDGHPPDPKDNLQAERGEMPPSPKHPQRTLTPSPLHPAASSLPGSPPRSPPTSPHRHPSLTRKHPRSQRGVPSPTESPPSPQGCLLEPSDLADEEVRHINSSAKDWGEHSEAGSCSTSPFVSPAASPVPLKNCSTSSLTAGSGKERDLKKFYSIDTKGFLTKPSWADDQRRHSIEICPSVRDGDCGFEERAEEKPRSPAHVQPESEYIHGARRKKKMSPPCISIDPPMEDDSGAASRTKPSENSMLRRRTPSCEFPAYREPLEPAEAQPGEPGCKAERRAQHLAIPGFSFEQSDGGGSLSSLSDLLDSGRSTPDCELRKPEPLKTQRSNAEKSKELLSVAKSPVRMQDLVTVATEEDIDEPV", "length": 2454, "header": "tr|A0A8V0Z855-1|A0A8V0Z855_CHICK Isoform 1 of Voltage-dependent T-type calcium channel subunit alpha-1H OS=Gallus gallus OX=9031 GN=CACNA1H PE=3 SV=1 CANONICAL=A0A8V0Z855-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z849-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855/entry#A0A8V0Z849-1", "sequence": { "sequence": "MSDGESREPRPAGGEVRVPITVPPRRAAEQPLDDAGSAPSGSPSRDPPPDLASEEEEQVPYPALAPTAFFCLKQTTRPRSWCLRLVCNPWFEHVSMLVILLNCVTLGMFQPCEDVECQSERCTILEAFDDFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNRLDFFIVMAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDRNLATTYNLTFLHPYYRTDEAEENPFICSSHRENGMQKCSNIPTRKEYKVECTLSMDSYTPSLYNPDFSSKNACINWNQYYNVCMAGDVNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTIRLYNNWQSKRRKKVNPNNTTNGQSRRGKKRITSIHHLIHHHHHHHHHHYHISNGSPRGPRSNPEICDLELKVMKPGGQLMLPSPSPNLQSPVPPPDSESVHSIYHADCHVEGPQVNCKSSNAPASIKLTTGLSNHGNMNYPTILPSPTSKASSVPVPKGKKNGSSPVAVVNSPVTLGTDSYGKLQQLVGEHGLRRTPSRLSGLSVACPLPSPPGGTLSCELQDCPFCASLLEDPEFAFSESDSCDSDSNGIYEFTQDLRHGDHRDQLQQQRGRRKRKKKKPKERNKVTRLWKAFGSKLKRIVESKYFNRGIMIAILINTLSMGIEYHEQPDELTNALEISNIVFTSMFALEMLLKLLAFGLFGYIKNPYNIFDGIIVVISVWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSANFDDDFEKLKDLRATEMKMYSLAVTPNGHLEGRGSMPPPIIMRTAATPMPTPKCSPHMDSVHTFVDSRRGSNASLDPLTYDQKSSSSLRSSPCANWGTNSNWGSRRSSWNSLGRAPSLKKKNQSGERESLLSGEGKGSTDDDSDDAKSSTVSRPSLHRRAESLDYRSSLDLPELLQLPPMRHSLSISPMAVLPAEYQDCNGKMVHVPSEFFLHIDGHKEEAVDYEDDMEDSYCYRIRKVLEPYKPEWCKSHEDWSLYLFSPQNRFRVMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPHSTERIFLSVSNYIFTAIFVAEMMVKVVALGFFSGENTYLQSSWNVLDGVLVFVSIIDIIVSMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCDGPDVKNITTKTDCTNAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPIQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKEMYLSEAQRRPYYADYSPARKYIHTLCTSHYLDLFITFIIGVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAVLKLVAFGFRRFFKDRWNQLDLAIVLLSIVGITLEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCSEENPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIELEMSRGASTTSGSRGGAVALESRASCRSQEAMKSEPAAQAKHQALGGTAIPQPQDSQNMLTVRKISVSRMHSLPNDSYMFRPVMPAKAPFPLHEVEMEAYPCKSQRGSITSIRSQPVGTCSSLRVPPESLHVAVRSPGREGWHRWKVLPPHVVPRSPTLSKLLCRQEAVRTDSVDGHPPDPKDNLQAERGEMPPSPKHPQRTLTPSPLHPAASSLPGSPPRSPPTSPHRHPSLTRKHPRSQRGVPSPTESPPSPQGCLLEPSDLADEEVRHINSSAKDWGEHSEAGSCSTSPFVSPAASPVPLKNCSTSSLTAGSGKERDLKKFYSIDTKGFLTKPSWADDQRRHSIEICPSVRDGDCGFEERAEEKPRSPAHVQPESEYIHGARRKKKMSPPCISIDPPMEDDSGAASRTKPSENSMLRRRTPSCEFPAYREPLEPAEAQPGEPGCKAERRAQHLAIPGFSFEQSDGGGSLSSLSDLLDSGRSTPDCELRKPEPLKTQRSNAEKSKELLSVAKSPVRMQDLVTVATEEDIDEPV", "length": 2412, "header": "tr|A0A8V0Z849-1|A0A8V0Z855_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha-1H OS=Gallus gallus OX=9031 GN=CACNA1H PE=3 SV=1 CANONICAL=A0A8V0Z855-1" }, "locus": { "chromosome": "14", "start_pos": 5443563, "end_pos": 5243573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042069.1", "url": "https://www.ensembl.org/id/ENSGALT00010042069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024632.1", "url": "https://www.ensembl.org/id/ENSGALP00010024632.1" } ] } }, { "isoform_ac": "A0A8V0Z855-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855/entry#A0A8V0Z855-1", "sequence": { "sequence": "MSDGESREPRPAGGEVRVPITVPPRRAAEQPLDDAGSAPSGSPSRDPPPDLASEEEEQVPYPALAPTAFFCLKQTTRPRSWCLRLVCNPWFEHVSMLVILLNCVTLGMFQPCEDVECQSERCTILEAFDDFIFAFFAVEMVIKMVALGIFGQKCYLGDTWNRLDFFIVMAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDRNLATTYNLTFLHPYYRTDEAEENPFICSSHRENGMQKCSNIPTRKEYKVECTLSMDSYTPSLYNPDFSSKNACINWNQYYNVCMAGDVNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRENQLMQEQRARYLSNDSTIASFSEPGSCYEELLKYICHIFRKVKRRTIRLYNNWQSKRRKKVNPNNTTNGQSRRGKKRITSIHHLIHHHHHHHHHHYHISNGSPRGPRSNPEICDLELKVMKPGGQLMLPSPSPNLQSPVPPPDSESVHSIYHADCHVEGPQVNCKSSNAPASIKLTTGLSNHGNMNYPTILPSPTSKASSVPVPKGKKNGSSPVAVVNSPVTLGTDSYGKLQQLVGEHGLRRTPSRLSGLSVACPLPSPPGGTLSCELQDCPFCASLLEDPEFAFSESDSCDSDSNGIYEFTQDLRHGDHRDQLQQQRGRRKRKKKKPKERNKVTRLWKAFGSKLKRIVESKYFNRGIMIAILINTLSMGIEYHEQPDELTNALEISNIVFTSMFALEMLLKLLAFGLFGYIKNPYNIFDGIIVVISVWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSANFDDDFEKLKDLRATEMKMYSLAVTPNGHLEGRGSMPPPIIMRTAATPMPTPKCSPHMDSVHTFVDSRRGSNASLDPLTYDQKSSSSLRSSPCANWGTNSNWGSRRSSWNSLGRAPSLKKKNQSGERESLLSGEGKGSTDDDSDDAKSSTVSRPSLHRRAESLDYRSSLDLPELLQLPPMRHSLSISPMAVLPAEYQDCNGKMVHVPSEFFLHIDGHKEEAVDYEDDMEDSYCYRIRKVLEPYKPEWCKSHEDWSLYLFSPQNRFRVMCQKVIAHKMFDHVVLVFIFLNCITIALERPDIDPHSTERIFLSVSNYIFTAIFVAEMMVKVVALGFFSGENTYLQSSWNVLDGVLVFVSIIDIIVSMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCDGPDVKNITTKTDCTNAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGIDQQPIQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRRPYYADYSPARKYIHTLCTSHYLDLFITFIIGVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAVLKLVAFGFRRFFKDRWNQLDLAIVLLSIVGITLEEIEMNAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLDCSEENPCEGLSRHATFTNFGMAFLTLFRVSTGDNWNGIMKDTLRECTREDKHCLSYLPVISPVYFVTFVLIAQFVLVNVVVAVLMKHLEESNKEAKEDAEMDAEIELEMSRGASTTSGSRGGAVALESRASCRSQEAMKSEPAAQAKHQALEALSCENVSVAIPDTLEGAETPMMEILSFCSVSHHVLTPSHHPRGREAEGGTAIPQPQDSQNMLTVRKISVSRMHSLPNDSYMFRPVMPAKAPFPLHEVEMEAYPCKSQRGSITSIRSQPVGTCSSLRVPPESLHVAVRSPGREGWHRWKVLPPHVVPRSPTLSKLLCRQEAVRTDSVDGHPPDPKDNLQAERGEMPPSPKHPQRTLTPSPLHPAASSLPGSPPRSPPTSPHRHPSLTRKHPRSQRGVPSPTESPPSPQGCLLEPSDLADEEVRHINSSAKDWGEHSEAGSCSTSPFVSPAASPVPLKNCSTSSLTAGSGKERDLKKFYSIDTKGFLTKPSWADDQRRHSIEICPSVRDGDCGFEERAEEKPRSPAHVQPESEYIHGARRKKKMSPPCISIDPPMEDDSGAASRTKPSENSMLRRRTPSCEFPAYREPLEPAEAQPGEPGCKAERRAQHLAIPGFSFEQSDGGGSLSSLSDLLDSGRSTPDCELRKPEPLKTQRSNAEKSKELLSVAKSPVRMQDLVTVATEEDIDEPV", "length": 2454, "header": "tr|A0A8V0Z855-1|A0A8V0Z855_CHICK Isoform 1 of Voltage-dependent T-type calcium channel subunit alpha-1H OS=Gallus gallus OX=9031 GN=CACNA1H PE=3 SV=1 CANONICAL=A0A8V0Z855-1" }, "locus": { "chromosome": "14", "start_pos": 5443563, "end_pos": 5243573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042076.1", "url": "https://www.ensembl.org/id/ENSGALT00010042076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024637.1", "url": "https://www.ensembl.org/id/ENSGALP00010024637.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1064, "start_aa": "Thr", "end_pos": 1064, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1064", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2167, "start_aa": "Thr", "end_pos": 2167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2167", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "O95180-1", "protein_name": "Voltage-dependent T-type calcium channel subunit alpha-1H", "gene_name": "CACNA1H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" }, { "name": "high voltage-gated calcium channel activity", "id": "GO:0008331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" }, { "name": "low voltage-gated calcium channel activity", "id": "GO:0008332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of acrosome reaction", "id": "GO:2000344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z855" } ], "pmid": "" }, { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z855", "url": 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"id": "A0A8V0Z853", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCRIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853", "locus": { "chromosome": "14", "start_pos": 13580000, "end_pos": 13576683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018843", "url": "https://www.ensembl.org/id/ENSGALG00010018843" } ] } } ], "crossref": [ { "id": "A0A8V0Z853", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z853", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z853", "url": "https://www.orthodb.org/?gene=A0A8V0Z853", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z853-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRGRAAGPARPVKGPARGTGCTRPAGAAGPCRAVPEGPHDVHADARPQQAGHAAPHRSHAAAGGEQGGRAAGPAAARSLAPRQVSPAPRRDLGESPAQKLIFNRVNGKRPQVLLPHTSVPEESYTAAHEENVRFVYEAWQEVEQQLDGGQRGESARGPVQYVEKTPNPRLKHFVPIDLEEWWAQQFLAKIENCS", "length": 194, "header": "tr|A0A8V0Z853-1|A0A8V0Z853_CHICK Isoform 1 of MAPK regulated corepressor interacting protein 2 OS=Gallus gallus OX=9031 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0A8V0Z853-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z853-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853/entry#A0A8V0Z853-1", "sequence": { "sequence": "GRGRAAGPARPVKGPARGTGCTRPAGAAGPCRAVPEGPHDVHADARPQQAGHAAPHRSHAAAGGEQGGRAAGPAAARSLAPRQVSPAPRRDLGESPAQKLIFNRVNGKRPQVLLPHTSVPEESYTAAHEENVRFVYEAWQEVEQQLDGGQRGESARGPVQYVEKTPNPRLKHFVPIDLEEWWAQQFLAKIENCS", "length": 194, "header": "tr|A0A8V0Z853-1|A0A8V0Z853_CHICK Isoform 1 of MAPK regulated corepressor interacting protein 2 OS=Gallus gallus OX=9031 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0A8V0Z853-1" }, "locus": { "chromosome": "14", "start_pos": 13579571, "end_pos": 13576739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045503.1", "url": "https://www.ensembl.org/id/ENSGALT00010045503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027147.1", "url": "https://www.ensembl.org/id/ENSGALP00010027147.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z853", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z853" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z854-1", "uniprot_ac": "A0A8V0Z854", "uniprot_id": "A0A8V0Z854_CHICK", "mass": { "chemical_mass": 68699.0, "monoisotopic_mass": 68699.0 }, "refseq": { "ac": "NP_001038107", "name": "zinc finger and BTB domain-containing protein 48", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" }, "gene_names": [ { "name": "ZBTB48", "type": "recommended", "evidence": [ { "id": "A0A8V0Z854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ] }, { "name": "HKR3", "type": "synonym", "evidence": [ { "id": "NP_001038107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" } ] }, { "name": "ZBTB48", "type": "synonym", "evidence": [ { "id": "NP_001038107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 48", "type": "recommended", "evidence": [ { "id": "A0A8V0Z854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854/entry#names_and_taxonomy" } ] }, { "name": "GLI-Kruppel family member HKR3", "type": "synonym", "evidence": [ { "id": "NP_001038107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" } ] }, { "name": "Telomere zinc finger-associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 48", "type": "synonym", "evidence": [ { "id": "NP_001038107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AM161453.2, SRR13267662.7388.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Sep 23, 2021 this sequence version replaced NP_001038107.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107" } ] }, { "annotation": "Plays a critical role in transcriptional regulation and chromatin remodeling. Acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A. Acts as a transcription regulator of CIITA, the major factor regulating MHC class II gene expression. In addition, regulates cellular m6A/m6Am methylation on RNA by facilitating the recruitment of the RNA demethylase, FTO, to target mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854#function" }, { "database": "UniProtKB", "id": "ARBA00058760", "url": "https://www.uniprot.org/uniprotkb/ARBA00058760#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854", "locus": { "chromosome": "21", "start_pos": 560846, "end_pos": 567355, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018955", "url": "https://www.ensembl.org/id/ENSGALG00010018955" } ] } } ], "crossref": [ { "id": "A0A8V0Z854", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z854", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18232", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18232", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419370", "url": "https://www.ncbi.nlm.nih.gov/gene/419370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419370", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419370", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EPPGNRK", "url": "https://omabrowser.org/oma/group/EPPGNRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z854", "url": "https://www.orthodb.org/?gene=A0A8V0Z854", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001038107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z854-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAAAAAHSVRVLRELNRQRAAGQYCDATLGVGGREFRAHWPVLASCSRFFRSRGGGGGAGPVALPEGLADTFQLLLDFFYTGRLALTAHNRARLLAAAELLGVPDAVALCRAFRPATARQRPRRAPGPALHPAEPPEVLSPAVPERERQAGRPGPESAVIVPVPPPVSSPPAATGGGGTAVSDAEPLPEKKALRSKGKPPAGGAGAAGSKKGAAVPVECPTCHKSFLSKYYLKVHNRKHTGEKPFECSKCGKCYFRKENLLEHEARNCMSRTEQVFTCSVCQEVFKRRMELRLHMVSHTGEMPYKCSSCVQQFMQKKDLQSHMIKLHGAPKPHACSTCSKCFLSRTELRLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCHHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHIASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKAVVVALQPPQELEVGSAEVIVESLSHGPLPEEIPVQRLCSNDNFPTADVIEQSLIITTTIPDDCET", "length": 616, "header": "tr|A0A8V0Z854-1|A0A8V0Z854_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 48 OS=Gallus gallus OX=9031 GN=ZBTB48 PE=3 SV=1 CANONICAL=A0A8V0Z854-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z854-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854/entry#A0A8V0Z854-1", "sequence": { "sequence": "MAGAAAAAHSVRVLRELNRQRAAGQYCDATLGVGGREFRAHWPVLASCSRFFRSRGGGGGAGPVALPEGLADTFQLLLDFFYTGRLALTAHNRARLLAAAELLGVPDAVALCRAFRPATARQRPRRAPGPALHPAEPPEVLSPAVPERERQAGRPGPESAVIVPVPPPVSSPPAATGGGGTAVSDAEPLPEKKALRSKGKPPAGGAGAAGSKKGAAVPVECPTCHKSFLSKYYLKVHNRKHTGEKPFECSKCGKCYFRKENLLEHEARNCMSRTEQVFTCSVCQEVFKRRMELRLHMVSHTGEMPYKCSSCVQQFMQKKDLQSHMIKLHGAPKPHACSTCSKCFLSRTELRLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCHHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHIASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKAVVVALQPPQELEVGSAEVIVESLSHGPLPEEIPVQRLCSNDNFPTADVIEQSLIITTTIPDDCET", "length": 616, "header": "tr|A0A8V0Z854-1|A0A8V0Z854_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 48 OS=Gallus gallus OX=9031 GN=ZBTB48 PE=3 SV=1 CANONICAL=A0A8V0Z854-1" }, "locus": { "chromosome": "21", "start_pos": 567280, "end_pos": 561332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045883.1", "url": "https://www.ensembl.org/id/ENSGALT00010045883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027342.1", "url": "https://www.ensembl.org/id/ENSGALP00010027342.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419370", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419370", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V777-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "Zbtb48", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSRFFQRIYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQPQTSAGQAQSGPGQVSSQDVKSHLKEPTDLDEEEVFRTLSLASVDQEPRDGEQPQLSTPAQSSPAFLCGKLKQVLKPSPPADKESEDSKEPPRPFEAEGAPLQGESNEWEVVVQVEDDRDGDGDYASEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPTEGRKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIDDEKMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASSGVLEPSLIITAAVPEDCDT", "length": 683 }, "evidence": [ { "id": "A0A8V0Z854", "url": "https://omabrowser.org/oma/group/A0A8V0Z854/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10074-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "ZBTB48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQSLYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAARELRVPEAVELCQSFKPKTSVGQAAGGQSGLGPPASQNVNSHVKEPAGLEEEEVSRTLGLVPRDQEPRGSHSPQRPQLHSPAQSEGPSSLCGKLKQALKPCPLEDKKPEDCKVPPRPLEAEGAQLQGGSNEWEVVVQVEDDGDGDYMSEPEAVLTRRKSNVIRKPCAAEPALSAGSLAAEPAENRKGTAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPHVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPAELEVGSAEVIVESLAQGGLASQLPGQRLCAEESFTGPGVLEPSLIITAAVPEDCDT", "length": 688 }, "evidence": [ { "id": "A0A8V0Z854", "url": "https://omabrowser.org/oma/group/A0A8V0Z854/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1H9T6-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "Zbtb48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQRIYGDGTGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQPQTSVGQAQSGLGQPASQDVKSHLKEPTDLDEEEVFRTLSLASVDQEPRDTEQPQLGTPAQSTTAFLCGKLTQALKPSPSEDKESEDCKEPPRPFEAGGAPLQGESNEWEVVVQVEDDRDGDYVSEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPTDSRKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRLHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASPGVLEPSLIITAAVPEDCDT", "length": 681 }, "evidence": [ { "id": "A0A8V0Z854", "url": "https://omabrowser.org/oma/group/A0A8V0Z854/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "telomere maintenance via telomere lengthening", "id": "GO:0010833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010833", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z854", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 90, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z854" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 246, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z857-1", "uniprot_ac": "A0A8V0Z857", "uniprot_id": "A0A8V0Z857_CHICK", "mass": { "chemical_mass": 59627.0, "monoisotopic_mass": 59627.0 }, "refseq": { "ac": "XP_046754842", "name": "repulsive guidance molecule A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754842" }, "gene_names": [ { "name": "RGMA", "type": "recommended", "evidence": [ { "id": "A0A8V0Z857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857" } ] }, { "name": "RGMA", "type": "synonym", "evidence": [ { "id": "XP_046754842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754842" } ] } ], "protein_names": [ { "name": "Repulsive guidance molecule family member a", "type": "synonym", "evidence": [ { "id": "A0A8V0Z857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857/entry#names_and_taxonomy" } ] }, { "name": "repulsive guidance molecule A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046754842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754842" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754842" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z857", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGMA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857", "locus": { "chromosome": "10", "start_pos": 14685502, "end_pos": 14707835, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018548", "url": "https://www.ensembl.org/id/ENSGALG00010018548" } ] } } ], "crossref": [ { "id": "A0A8V0Z857", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z857", "database": "AlphaFoldDB", "categories": [] }, { "id": "395214", "url": "https://www.ncbi.nlm.nih.gov/gene/395214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ICHYERG", "url": "https://omabrowser.org/oma/group/ICHYERG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z857", "url": "https://www.orthodb.org/?gene=A0A8V0Z857", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31428:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31428:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046754842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z857", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z857-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLREGDAAPRVPLSEAALLPAGAALRRAGGAAFLPPPPPRHRCSFLSFLFFFHFFIIIVIFLLKKKKDRGKKKKAPCTHPPRGGLERLMRPLRERIVVKARAGWMGMGRGAGSTALGLFQILPVFLCIFPPVTSPCKILKCNSEFWAATSGSHHLGAEETPEFCTALRAYAHCTRRTARTCRGDLAYHSAVHGIDDLMVQHNCSKDGPTSQPRLRTLPPGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDTFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSSATATSKLTIIFKSFQECVEQKVYQAEMDELPAAFADGSKNGGDKHGANSLKITEKVSGQHIEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQTFRLAQAAEGRARRKGPSLPAPPEAFTYESATAKCREKLPVEDLYFQSCVFDLLTTGDVNFMLAAYYAFEDVKMLHSNKDKLHLYERTRALAPGNAAPSEHPWALPALWVALLSLSQCWLGLL", "length": 538, "header": "tr|A0A8V0Z857-1|A0A8V0Z857_CHICK Isoform 1 of Repulsive guidance molecule family member a OS=Gallus gallus OX=9031 GN=RGMA PE=3 SV=1 CANONICAL=A0A8V0Z857-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z857-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857/entry#A0A8V0Z857-1", "sequence": { "sequence": "MLREGDAAPRVPLSEAALLPAGAALRRAGGAAFLPPPPPRHRCSFLSFLFFFHFFIIIVIFLLKKKKDRGKKKKAPCTHPPRGGLERLMRPLRERIVVKARAGWMGMGRGAGSTALGLFQILPVFLCIFPPVTSPCKILKCNSEFWAATSGSHHLGAEETPEFCTALRAYAHCTRRTARTCRGDLAYHSAVHGIDDLMVQHNCSKDGPTSQPRLRTLPPGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDTFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSSATATSKLTIIFKSFQECVEQKVYQAEMDELPAAFADGSKNGGDKHGANSLKITEKVSGQHIEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQTFRLAQAAEGRARRKGPSLPAPPEAFTYESATAKCREKLPVEDLYFQSCVFDLLTTGDVNFMLAAYYAFEDVKMLHSNKDKLHLYERTRALAPGNAAPSEHPWALPALWVALLSLSQCWLGLL", "length": 538, "header": "tr|A0A8V0Z857-1|A0A8V0Z857_CHICK Isoform 1 of Repulsive guidance molecule family member a OS=Gallus gallus OX=9031 GN=RGMA PE=3 SV=1 CANONICAL=A0A8V0Z857-1" }, "locus": { "chromosome": "10", "start_pos": 14707831, "end_pos": 14687871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044870.1", "url": "https://www.ensembl.org/id/ENSGALT00010044870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026789.1", "url": "https://www.ensembl.org/id/ENSGALP00010026789.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z857", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z857", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z857" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z857", "url": 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z862-1", "uniprot_ac": "A0A8V0Z862", "uniprot_id": "A0A8V0Z862_CHICK", "mass": { "chemical_mass": 32741.0, "monoisotopic_mass": 32741.0 }, "refseq": {}, "gene_names": [ { "name": "NBL1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862" } ] } ], "protein_names": [ { "name": "Neuroblastoma suppressor of tumorigenicity 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR016728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z862", "url": "https://www.orthodb.org/?gene=A0A8V0Z862", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF40", "url": "https://www.orthodb.org/?gene=A0A8V0ZF40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15283:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15283:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z862", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z862-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFVSAKQRLTKQVEQQHQSWLDFCPWFGCGQDTAQAGQRQDRRWGPIPALSPLPTSRCQLGTRSCCTGHGLILYASLVMNERRSRKRARLAFETTPIPDCEPAFRCGCRFSAELAMMLWFVVGALFPALLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLDCPGNDEIPRVDKLVEKILHCSCQACGKEPSHEGALFNVYLNAEENMPAEGPGPHHYAHHQQEVEEPPASSHHHHEEEGDE", "length": 294, "header": "tr|A0A8V0Z862-1|A0A8V0Z862_CHICK Isoform 1 of Neuroblastoma suppressor of tumorigenicity 1 OS=Gallus gallus OX=9031 GN=NBL1 PE=3 SV=1 CANONICAL=A0A8V0Z862-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z862-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862/entry#A0A8V0Z862-1", "sequence": { "sequence": "MDFVSAKQRLTKQVEQQHQSWLDFCPWFGCGQDTAQAGQRQDRRWGPIPALSPLPTSRCQLGTRSCCTGHGLILYASLVMNERRSRKRARLAFETTPIPDCEPAFRCGCRFSAELAMMLWFVVGALFPALLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLDCPGNDEIPRVDKLVEKILHCSCQACGKEPSHEGALFNVYLNAEENMPAEGPGPHHYAHHQQEVEEPPASSHHHHEEEGDE", "length": 294, "header": "tr|A0A8V0Z862-1|A0A8V0Z862_CHICK Isoform 1 of Neuroblastoma suppressor of tumorigenicity 1 OS=Gallus gallus OX=9031 GN=NBL1 PE=3 SV=1 CANONICAL=A0A8V0Z862-1" }, "locus": { "chromosome": "21", "start_pos": 4770537, "end_pos": 4763888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049813.1", "url": "https://www.ensembl.org/id/ENSGALT00010049813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029431.1", "url": "https://www.ensembl.org/id/ENSGALP00010029431.1" } ] } }, { "isoform_ac": "A0A8V0ZF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862/entry#A0A8V0ZF40-1", "sequence": { "sequence": "MLSKFDVRSCRFSAELAMMLWFVVGALFPALLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLDCPGNDEIPRVDKLVEKILHCSCQACGKEPSHEGALFNVYLNAEENMPAEGPGPHHYAHHQQEVEEPPASSHHHHEEEGDE", "length": 195, "header": "tr|A0A8V0ZF40-1|A0A8V0ZF40_CHICK Computationally mapped isoform of Neuroblastoma suppressor of tumorigenicity 1 OS=Gallus gallus OX=9031 GN=NBL1 PE=3 SV=1 CANONICAL=A0A8V0Z862-1" }, "locus": { "chromosome": "21", "start_pos": 4770537, "end_pos": 4760208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049821.1", "url": "https://www.ensembl.org/id/ENSGALT00010049821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029436.1", "url": "https://www.ensembl.org/id/ENSGALP00010029436.1" } ] } }, { "isoform_ac": "A0A8V0ZLD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862/entry#A0A8V0ZLD4-1", "sequence": { "sequence": "MCPPSPGCCRFSAELAMMLWFVVGALFPALLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLDCPGNDEIPRVDKLVEKILHCSCQACGKEPSHEGALFNVYLNAEENMPAEGPGPHHYAHHQQEAFLSNSYPHALLSTTPRGWRSVLRHEQDVGLELRGQRRAGGFCCKTTCTS", "length": 226, "header": "tr|A0A8V0ZLD4-1|A0A8V0ZLD4_CHICK Computationally mapped isoform of Neuroblastoma suppressor of tumorigenicity 1 OS=Gallus gallus OX=9031 GN=NBL1 PE=3 SV=1 CANONICAL=A0A8V0Z862-1" }, "locus": { "chromosome": "21", "start_pos": 4770780, "end_pos": 4762374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049816.1", "url": "https://www.ensembl.org/id/ENSGALT00010049816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029433.1", "url": "https://www.ensembl.org/id/ENSGALP00010029433.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sequestering of BMP from receptor via BMP binding", "id": "GO:0038098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z862", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z862" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": 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CANONICAL=A0A8V0Z8Q5-1" }, "locus": { "chromosome": "3", "start_pos": 9852496, "end_pos": 9823854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045908.1", "url": "https://www.ensembl.org/id/ENSGALT00010045908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027352.1", "url": "https://www.ensembl.org/id/ENSGALP00010027352.1" } ] } }, { "isoform_ac": "A0A8V0Z8Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5/entry#A0A8V0Z8Q0-1", "sequence": { "sequence": "MEPVLFQCMRIVFFFFWSIIGFDQSSVSDSMGNRGNNEKSVPQLLISDLKFEKKSLAKLMFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGVWREISVCGNVFSLRETRSAQQRGKMVENETNQLQDGSLIDLCGATLLWRTAEGLSRTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD", "length": 477, "header": "tr|A0A8V0Z8Q0-1|A0A8V0Z8Q0_CHICK Computationally mapped isoform of Pellino E3 ubiquitin protein ligase family member 3 OS=Gallus gallus OX=9031 GN=PELI3 PE=3 SV=1 CANONICAL=A0A8V0Z8Q5-1" }, "locus": { "chromosome": "3", "start_pos": 9843273, "end_pos": 9823854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045892.1", "url": "https://www.ensembl.org/id/ENSGALT00010045892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027344.1", "url": "https://www.ensembl.org/id/ENSGALP00010027344.1" } ] } }, { "isoform_ac": "A0A8V0Z8Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5/entry#A0A8V0Z8Q5-1", "sequence": { "sequence": "MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGVWREISVCGNVFSLRETRSAQQRGKMVRVENETNQLQDGSLIDLCGATLLWRTAEGLSRTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD", "length": 419, "header": "tr|A0A8V0Z8Q5-1|A0A8V0Z8Q5_CHICK Isoform 1 of Pellino E3 ubiquitin protein ligase family member 3 OS=Gallus gallus OX=9031 GN=PELI3 PE=3 SV=1 CANONICAL=A0A8V0Z8Q5-1" }, "locus": { "chromosome": "3", "start_pos": 9830916, "end_pos": 9823854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045903.1", "url": "https://www.ensembl.org/id/ENSGALT00010045903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027349.1", "url": "https://www.ensembl.org/id/ENSGALP00010027349.1" } ] } }, { "isoform_ac": "A0A8V0ZFJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5/entry#A0A8V0ZFJ8-1", "sequence": { "sequence": "MSGNNEKSVPQLLISDLKFEKKSLAKLMFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGVWREISVCGNVFSLRETRSAQQRGKMVENETNQLQDGSLIDLCGATLLWRTAEGLSRTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD", "length": 445, "header": "tr|A0A8V0ZFJ8-1|A0A8V0ZFJ8_CHICK Computationally mapped isoform of Pellino E3 ubiquitin protein ligase family member 3 OS=Gallus gallus OX=9031 GN=PELI3 PE=3 SV=1 CANONICAL=A0A8V0Z8Q5-1" }, "locus": { "chromosome": "3", "start_pos": 9862720, "end_pos": 9823854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045895.1", "url": "https://www.ensembl.org/id/ENSGALT00010045895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027346.1", "url": "https://www.ensembl.org/id/ENSGALP00010027346.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "ubiquitin-ubiquitin ligase activity", "id": "GO:0034450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034450", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "regulation of Toll signaling pathway", "id": "GO:0008592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "negative regulation of necroptotic process", "id": "GO:0060546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" }, { "id": "PF04710", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04710" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pellino FHA", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 271, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q5" }, { "id": "PF20723", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20723" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pellino RING", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 419, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z875-1", "uniprot_ac": "A0A8V0Z875", "uniprot_id": "A0A8V0Z875_CHICK", "mass": { "chemical_mass": 78036.0, "monoisotopic_mass": 78036.0 }, "refseq": { "ac": "XP_040557023", "name": "F-box only protein 34 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557023" }, "gene_names": [ { "name": "FBXO34", "type": "recommended", "evidence": [ { "id": "A0A8V0Z875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875" } ] }, { "name": "FBXO34", "type": "synonym", "evidence": [ { "id": "XP_040557023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557023" } ] } ], "protein_names": [ { "name": "F-box only protein 34 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040557023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557023" } ] }, { "name": "F-box protein 34", "type": "synonym", "evidence": [ { "id": "A0A8V0Z875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z875", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875", "locus": { "chromosome": "5", "start_pos": 55796103, "end_pos": 55839405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018551", "url": "https://www.ensembl.org/id/ENSGALG00010018551" } ] } } ], "crossref": [ { "id": "cd22176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423554", "url": "https://www.ncbi.nlm.nih.gov/gene/423554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MKNSNRY", "url": "https://omabrowser.org/oma/group/MKNSNRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z875", "url": "https://www.orthodb.org/?gene=A0A8V0Z875", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z875", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z875-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLKPYLKLQRKERSPEVSQDSLRGPPMSQRSTQDKYANNCTKLSVFPTPPLVTPSRKLLGIIYPNTMCNMNGKGPADGLSAREKKNVLSATIHQGEEGEGPLDVWAVVKPGNTKEKIAFFAAQQCSGNNRLGSMKLKSTWDIDGRTVKRRKKTVDLKKAKIQLERMREANARCSQPEPFVCGIEHCSVHYVNDSGEGVFPGRSLSVIEMVAFLEQRASALLVDCAKTCTSASTARLSAPSKGALPSSDPFSAAGPCEVHERGTCGSSEQQQSEPVRVLDMVAKLESECLRRQSERDGGSLSRNNSFRRNVGRVLLASSTQPGAEPGRASAGSVGRGEELGAAGAGCGARCGDAGLWDGAASAPQPFPPGLEAHVGNAGSGLAHAVLAIAAGRGDAERRVEPPRALPALCPAVAGVPVDSLPSKSATADCTSKEAVILSKQSLHPARKEPLCISISVTKTEKGCRKEKLPPSSSSEDPLPGRLFFLQAEQNATHAPQPLRECTQEKPGEGVQNEDEDALESDKSCVRTNVSPEPSALSVPPPEGALQALDASCLKRQVSHDFLETRFKIQQLLEPQQYMAFLPHHIIVKIFGLLPTRSLVALKCTCYYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGIPGCKLGLHDNHWVPACHSFNRALHKKTRGAGAEGEEEY", "length": 717, "header": "tr|A0A8V0Z875-1|A0A8V0Z875_CHICK Isoform 1 of F-box protein 34 OS=Gallus gallus OX=9031 GN=FBXO34 PE=4 SV=1 CANONICAL=A0A8V0Z875-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z875-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875/entry#A0A8V0Z875-1", "sequence": { "sequence": "MHLKPYLKLQRKERSPEVSQDSLRGPPMSQRSTQDKYANNCTKLSVFPTPPLVTPSRKLLGIIYPNTMCNMNGKGPADGLSAREKKNVLSATIHQGEEGEGPLDVWAVVKPGNTKEKIAFFAAQQCSGNNRLGSMKLKSTWDIDGRTVKRRKKTVDLKKAKIQLERMREANARCSQPEPFVCGIEHCSVHYVNDSGEGVFPGRSLSVIEMVAFLEQRASALLVDCAKTCTSASTARLSAPSKGALPSSDPFSAAGPCEVHERGTCGSSEQQQSEPVRVLDMVAKLESECLRRQSERDGGSLSRNNSFRRNVGRVLLASSTQPGAEPGRASAGSVGRGEELGAAGAGCGARCGDAGLWDGAASAPQPFPPGLEAHVGNAGSGLAHAVLAIAAGRGDAERRVEPPRALPALCPAVAGVPVDSLPSKSATADCTSKEAVILSKQSLHPARKEPLCISISVTKTEKGCRKEKLPPSSSSEDPLPGRLFFLQAEQNATHAPQPLRECTQEKPGEGVQNEDEDALESDKSCVRTNVSPEPSALSVPPPEGALQALDASCLKRQVSHDFLETRFKIQQLLEPQQYMAFLPHHIIVKIFGLLPTRSLVALKCTCYYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGIPGCKLGLHDNHWVPACHSFNRALHKKTRGAGAEGEEEY", "length": 717, "header": "tr|A0A8V0Z875-1|A0A8V0Z875_CHICK Isoform 1 of F-box protein 34 OS=Gallus gallus OX=9031 GN=FBXO34 PE=4 SV=1 CANONICAL=A0A8V0Z875-1" }, "locus": { "chromosome": "5", "start_pos": 55799884, "end_pos": 55797734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044889.1", "url": "https://www.ensembl.org/id/ENSGALT00010044889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026808.1", "url": "https://www.ensembl.org/id/ENSGALP00010026808.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 49, "start_aa": "Thr", "end_pos": 49, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr49", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A0H4-1", "protein_name": "F-box protein 34", "gene_name": "FBXO34", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHLKPYWKLQKKMRPLETSKETLRTPMSHQEAINDEKCKASCMKPSVFPSASLGKTSSRKPFGILSPNVLCSMSGKSSVESSLNVNVKKNTPSATIHQGEEGEGPLDIWAVVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKIQLERMKEVNSRCYQPEPFACGIEHCSVHCVSDSGDGVYTGRPLSVIQMVAFLEQRASALLASCAKNCNNSPVVVRLSGQSRGVPPASEPFSAPRVCEEATTERRNPEVGEPQCEPVRVLDMVAKLESECLKRQSQREPGSLSRNNSFHRNVGRVLLVNGTQAEESKTNKGALEVPDTQVNPAVSVSVVCDPLRADRCSPKVDQAWAGTPLPVGVSFHMDSAELEPDQQTAMKSRNKYDVEMTEELVGSPFSPRTCPQAIELPTDAVDCMSEELVPLASQNPDQRRKESLCISITVSEVKKDQPSGLQSHEDPLPGMLFFLPSGQHQLGCSQLNESTTEESSKASQLEGDAEDDSASEEKTISADAFDPLASPMESTLPVLEASTWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTETEEEY", "length": 709 }, "evidence": [ { "id": "A0A8V0Z875", "url": "https://omabrowser.org/oma/group/A0A8V0Z875/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BH27-1", "protein_name": "F-box only protein 34", "gene_name": "fbxo34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQKCETISYCNPTPYREPRLRASNSPAVWRLNNMHLKPYPKPQDKEIHRESVRDATRGLHADQQGVLRKEWGVHQSCGLMGSPGNGTANRCPLGVISPNTLRCNTNSGSNVPTRVSGARKSKSLPITTFTSSLVLLSPSTGLENEGSLGIYQGEDEEGSLDIWAVIKPGNTKEKIAIFASQMCSSTCDSVIDDGSETEAIAPELRTASVKNKGCWDVDCSLPKRRRRSENPDKLKILEPLSPKLEMHNVLQQEAHCENINPCQGLAEDAVKTEGEEDEKTVSVVEMVAYLEQMANDQQIGSKSPSLRSTSTIILSKVGSITQPDEQQSKAKEQLEVQEEEGESIRVLDMVAKLESQCLNRQNLRENGGELSRNNSLRRKVGRVLLAGSEPYPLQSQPVSPTDPQDSGVESVPQELGSDFDKRSSQIKTLELIEITKCELDICAPEEKETSCIARLETCTAVETVNNLQSSPKDASSESSEEPLPGMLFFAKSSPQPPKAQHLPSLKSRSLNKEPSRIHKLPVDIKASFTEEIRDELASEIQNHRIFEETESRETCLVSQEPVPFPLRRLVSHEFLETRFKIQLLLEPQQYMAFLPHHIIVKIFCLLPTESLAALKCTCHYFKCIIESYGVRPADSRWVIDPRYKDDPCKQCKKRYDRGDVSLCRWHHKPYCQSLPYGPGYWMCCRRSHKDSLGCNVGLHDNRWVPAFHSINVPIYKRSRDTDEDS", "length": 726 }, "evidence": [ { "id": "A0A8V0Z875", "url": "https://omabrowser.org/oma/group/A0A8V0Z875/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B5DF06-1", "protein_name": "F-box protein 34", "gene_name": "Fbxo34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHLKPYWKLQKKERPLSHGNTDGDAKGRANCMKPTPSPSASPVKASSRKPFGILSPNVLCSMSGKSPVENSLSVKATRNAPSAAVQQTEGGLPGSWAIVKPGNTKEKIAFFAAHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQCYQSEPFACGVEHCSVHYMSDSGDGVYAARPLSVIQMVAFLEQRATALLASCTKNCTNSPAIVKISGQSRGMPPVPEPFSAPDTCEESKERENPEIGRSQSEPVRVLDMVARLESECLKHQGQREPGSLSRNNSFRRNVGRVLLTNGSQASDKNGEGSADTPGTQVHPLQLVSVGEGPPATDRSAGEQAWDGTSQGCPSLPADVSFHTDSTESEPALHTAVKHCSRNDVEMAEEFDELPTDAVSCRELVTLTSHSPEQRQEPLCVSITVCTVEKAQPSALDPLEEPLPGMLFFLSPGQDQQAHPQLSEHPAPEATEASQPPDAAEGSSAREEKDASLEPLVPAASGEGSTSQGLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIMVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKSRGSETEEEY", "length": 681 }, "evidence": [ { "id": "A0A8V0Z875", "url": "https://omabrowser.org/oma/group/A0A8V0Z875/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XI1-1", "protein_name": "F-box only protein 34", "gene_name": "Fbxo34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLKLYWKLQKKERPLEVSRDTLRTPMSHGKANGDVKARASYMKPTVLPSASLVKASSRKPFGILSPNVLCSMSGKSPVENSLNVKAKKNVLSAAVHQSEEGLPGTWAIVKPGNTKEKIAFFAAHQYSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQCYQSEPFVCGVEHCSVHYMSDSGDGVCAARPLSVIQMVAFLEQKATALLASCTKNCTNSPAIVKISGQSRGIPPAPEPFSAPETCEEPKEQENPETGRSQGEPVRVLDMVARLESECLKHQGQREPGSLSRNNSFRRNVGRVLLTNGSQASDKSEEGSADTADPQENPLQPVSVGEEPSVTEHHSVGEQAWDGTSQSCPSLPATVSFHMDSTDLEPGQQTAMKSCSRDDVEMVEEFDELPTDAVRRIRRELVTVTKHSPEQRQDPLCISITVCTVEKDRPAALDSLEEPLPGMLFFLSSGQDQQAHPQLREHPAPEASEASQPQDAAEGSSAGEEKDASVEPLLPAASPGGSTSQVLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIIVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKTRGSETEEEY", "length": 695 }, "evidence": [ { "id": "A0A8V0Z875", "url": "https://omabrowser.org/oma/group/A0A8V0Z875/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWN3-1", "protein_name": "F-box only protein 34", "gene_name": "FBXO34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY", "length": 711 }, "evidence": [ { "id": "A0A8V0Z875", "url": "https://omabrowser.org/oma/group/A0A8V0Z875/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z875" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 628, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 49, 54 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 529, "end_pos": 531 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z888-1", "uniprot_ac": "A0A8V0Z888", "uniprot_id": "A0A8V0Z888_CHICK", "mass": { "chemical_mass": 108465.0, "monoisotopic_mass": 108465.0 }, "refseq": { "ac": "XP_025006731", "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006731" }, "gene_names": [ { "name": "MDGA2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" } ] }, { "name": "MDGA2", "type": "synonym", "evidence": [ { "id": "XP_025006731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006731" } ] } ], "protein_names": [ { "name": "MAM domain containing glycosylphosphatidylinositol anchor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888/entry#names_and_taxonomy" } ] }, { "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "type": "synonym", "evidence": [ { "id": "XP_025006731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025006731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006731" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z888", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MDGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888", "locus": { "chromosome": "5", "start_pos": 56496484, "end_pos": 56854740, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018983", "url": "https://www.ensembl.org/id/ENSGALG00010018983" } ] } } ], "crossref": [ { "id": "A0A8V0Z888", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z888", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012228", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012228", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423563", "url": "https://www.ncbi.nlm.nih.gov/gene/423563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423563", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423563", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGQFDAQ", "url": "https://omabrowser.org/oma/group/TGQFDAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z888", "url": "https://www.orthodb.org/?gene=A0A8V0Z888", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFN8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIA0", "url": "https://www.orthodb.org/?gene=F1NIA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025006731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z888", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z888-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIA0", "url": "https://www.uniprot.org/uniprotkb/F1NIA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIA0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVAIGLLGLLTVLLEGSSGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRIANIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCSIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAVTLVCVTTGGEPAPSLTWVRSAGGLPEKTVLNGGTLTIPAIASEDAGTYSCVANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGILRIVNVSREMTGTYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPTFLEIRQGQGRSITMSCRVLRAYPTRVLTYEWRLGSKLLRTGQFDLQDSTEYTVSSLSRDSYGVYNCNIINEAGAGRCSFLVTGKAYAPEFYYDTYNPLWQNRPRVYSYSLQWTQMNPSAVDRILAYRLGIRQVDATSITVPLVALMKTAGQQRWWEQEITVNGNIQKGELITYNLTELIKPEAYEVRLTPITRFGEGDSTIRVIKYSAPVNPHLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRDTKYTPNTGPNADRTGSKEGFYMYIETSRPRLEGEKARLVSPVFSVAPKNPYGATNTAYCFSFYYHMYGQHIGSLNVYLRLKGQTAIENPLWSSSGNKGQHWNQARVNINPPTSFQLIFEGIRGPGIEGDIAIDDVSIVEGECMKSDQPANNLRSGAVGTLEHIRLIPVTILMFVLSHQR", "length": 972, "header": "tr|A0A8V0Z888-1|A0A8V0Z888_CHICK Isoform 1 of MAM domain containing glycosylphosphatidylinositol anchor 2 OS=Gallus gallus OX=9031 GN=MDGA2 PE=4 SV=1 CANONICAL=A0A8V0Z888-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z888-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888/entry#A0A8V0Z888-1", "sequence": { "sequence": "MDVAIGLLGLLTVLLEGSSGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRIANIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCSIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAVTLVCVTTGGEPAPSLTWVRSAGGLPEKTVLNGGTLTIPAIASEDAGTYSCVANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGILRIVNVSREMTGTYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPTFLEIRQGQGRSITMSCRVLRAYPTRVLTYEWRLGSKLLRTGQFDLQDSTEYTVSSLSRDSYGVYNCNIINEAGAGRCSFLVTGKAYAPEFYYDTYNPLWQNRPRVYSYSLQWTQMNPSAVDRILAYRLGIRQVDATSITVPLVALMKTAGQQRWWEQEITVNGNIQKGELITYNLTELIKPEAYEVRLTPITRFGEGDSTIRVIKYSAPVNPHLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRDTKYTPNTGPNADRTGSKEGFYMYIETSRPRLEGEKARLVSPVFSVAPKNPYGATNTAYCFSFYYHMYGQHIGSLNVYLRLKGQTAIENPLWSSSGNKGQHWNQARVNINPPTSFQLIFEGIRGPGIEGDIAIDDVSIVEGECMKSDQPANNLRSGAVGTLEHIRLIPVTILMFVLSHQR", "length": 972, "header": "tr|A0A8V0Z888-1|A0A8V0Z888_CHICK Isoform 1 of MAM domain containing glycosylphosphatidylinositol anchor 2 OS=Gallus gallus OX=9031 GN=MDGA2 PE=4 SV=1 CANONICAL=A0A8V0Z888-1" }, "locus": { "chromosome": "5", "start_pos": 56854616, "end_pos": 56498279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045953.1", "url": "https://www.ensembl.org/id/ENSGALT00010045953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027377.1", "url": "https://www.ensembl.org/id/ENSGALP00010027377.1" } ] } }, { "isoform_ac": "A0A8V0ZFN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888/entry#A0A8V0ZFN8-1", "sequence": { "sequence": "MDVAIGLLGLLTVLLEGSSGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRIANIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCSIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAVTLVCVTTGGEPAPSLTWVRSAGGLPEKTVLNGGTLTIPAIASEDAGTYSCVANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGILRIVNVSREMTGTYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPTFLEIRQGQGRSITMSCRVLRAYPTRVLTYEWRLGSKLLRTGQFDLQDSTEYTVSSLSRDSYGVYNCNIINEAGAGRCSFLVTGKAYAPEFYYDTYNPLWQNRPRVYSYSLQWTQMNPSAVDRILAYRLGIRQAGQQRWWEQEITVNGNIQKGELITYNLTELIKPEAYEVRLTPITRFGEGDSTIRVIKYSGEFHCGFEDGNICLFTQDDTDNFDWTKQSTATRDTKYTPNTGPNADRTGSKEGFYMYIETSRPRLEGEKARLVSPVFSVAPKNPYGATNTAYCFSFYYHMYGQHIGSLNVYLRLKGQTAIENPLWSSSGNKGQHWNQARVNINPPTSFQLIFEGIRGPGIEGDIAIDDVSIVEGECMKSDQPANNLRSGAVGTLEHIRLIPVTILMFVLSHQR", "length": 949, "header": "tr|A0A8V0ZFN8-1|A0A8V0ZFN8_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 2 OS=Gallus gallus OX=9031 GN=MDGA2 PE=4 SV=1 CANONICAL=A0A8V0Z888-1" }, "locus": { "chromosome": "5", "start_pos": 56854616, "end_pos": 56498279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045957.1", "url": "https://www.ensembl.org/id/ENSGALT00010045957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027381.1", "url": "https://www.ensembl.org/id/ENSGALP00010027381.1" } ] } }, { "isoform_ac": "F1NIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888/entry#F1NIA0-1", "sequence": { "sequence": "MLAAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRIANIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCSIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAVTLVCVTTGGEPAPSLTWVRSAGGLPEKTVLNGGTLTIPAIASEDAGTYSCVANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGILRIVNVSREMTGTYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPTFLEIRQGQGRSITMSCRVLRAYPTRVLTYEWRLGSKLLRTGQFDLQDSTEYTVSSLSRDSYGVYNCNIINEAGAGRCSFLVTGKAYAPEFYYDTYNPLWQNRPRVYSYSLQWTQMNPSAVDRILAYRLGIRQAGQQRWWEQEITVNGNIQKGELITYNLTELIKPEAYEVRLTPITRFGEGDSTIRVIKYSAPVNPHLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRDTKYTPNTGPNADRTGSKEGFYMYIETSRPRLEGEKARLVSPVFSVAPKNPYGATNTAYCFSFYYHMYGQHIGSLNVYLRLKGQTAIENPLWSSSGNKGQHWNQARVNINPPTSFQLIFEGIRGPGIEGDIAIDDVSIVEGECMKSDQPANNLRSGAVGTLEHIRLIPVTILMFVLSHQR", "length": 935, "header": "tr|F1NIA0-1|A0A8V0Z888_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 2 OS=Gallus gallus OX=9031 GN=MDGA2 PE=4 SV=4 CANONICAL=A0A8V0Z888-1" }, "locus": { "chromosome": "5", "start_pos": 56851278, "end_pos": 56498279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045950.1", "url": "https://www.ensembl.org/id/ENSGALT00010045950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027375.1", "url": "https://www.ensembl.org/id/ENSGALP00010027375.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423563", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423563", "resource": "KEGG Pathway" }, { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "P60755-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "gene_name": "Mdga2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPTPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTGEFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVDGAVGILVHIWLFPVIILISILSPRR", "length": 949 }, "evidence": [ { "id": "A0A8V0Z888", "url": "https://omabrowser.org/oma/group/A0A8V0Z888/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60756-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "gene_name": "Mdga2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLVYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITSIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPMPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTGEFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVDGAVGILVHIWLFPVIILISILSPRR", "length": 949 }, "evidence": [ { "id": "A0A8V0Z888", "url": "https://omabrowser.org/oma/group/A0A8V0Z888/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z553-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "gene_name": "MDGA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPAPSLTWVRSFGTLPEKTVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYAVKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYSAPVNPHLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLATKNSVDGAVGILVHIWLFPIIVLISILSPRR", "length": 956 }, "evidence": [ { "id": "A0A8V0Z888", "url": "https://omabrowser.org/oma/group/A0A8V0Z888/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z888", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z888", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z888", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 127, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z888" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 762, "end_pos": 937, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8A4-1", "uniprot_ac": "A0A8V0Z8A4", "uniprot_id": "A0A8V0Z8A4_CHICK", "mass": { "chemical_mass": 48431.0, "monoisotopic_mass": 48431.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101749694", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A4" } ] } ], "protein_names": [ { "name": "LRRCT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A4/entry#names_and_taxonomy" } ] } ], "function": [], 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"MFFLVIFIFNCAAKAGLSLNISDSCPSMCKCAPEEVIHCNRAGLRALPGEIAASTVSLNLSNNYLRILTTNTFRNLTFLHSLWLDGNNLTFLSPGTFHALSKLRELDLSRNSRLTYLHANTFRGLLNLISLDLSHCNIFEIHPLLFSHLPSLERLNLASNNMRYVPQAFSNLSSLTRLSLESNHIEAIGRDSLKDLESLYDLNLRKNRIWIIQNGAFTRLLRLGVLNLGHNFIADLPNQLFNGLIQLKTMHLEANRITDIDCTFRLLLNLRNLYLNNNQISSISDSAFSYLNKLHFLHLSKNNLSSLPLRLFVELPKLKYVFLSHNPWKCDCKMFWFLRWTAMFRGALEGLDCSFPNRHNTTALGGPQPGDPMDCTAPPELESKDKCGAAGISVAPGPPAPTSEVFLLVAICHTWYFARRWDTSAHPIC", "length": 429, "header": "tr|A0A8V0Z8A4-1|A0A8V0Z8A4_CHICK Isoform 1 of LRRCT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101749694 PE=4 SV=1 CANONICAL=A0A8V0Z8A4-1" }, "locus": { "chromosome": "4", "start_pos": 2959838, "end_pos": 2958231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045616.1", "url": "https://www.ensembl.org/id/ENSGALT00010045616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027202.1", "url": "https://www.ensembl.org/id/ENSGALP00010027202.1" } ] } } ], "glycosylation": [ { 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] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"A0A8V0Z8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2/entry#names_and_taxonomy" } ] }, { "name": "pVHL", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2/entry#names_and_taxonomy" } ] }, { "name": "von Hippel-Lindau disease tumor suppressor", "type": "synonym", "evidence": [ { "id": "XP_414447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414447" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_414447.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414447" } ] }, { "annotation": "Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. Acts as a negative regulator of mTORC1 by promoting ubiquitination and degradation of RPTOR.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2#function" }, { "database": "UniProtKB", "id": "ARBA00059036", "url": "https://www.uniprot.org/uniprotkb/ARBA00059036#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VHL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z8B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05468", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05468", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416117", "url": "https://www.ncbi.nlm.nih.gov/gene/416117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MNQRVEQ", "url": "https://omabrowser.org/oma/group/MNQRVEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDSLPVSGRLRARVLPSRGRAAGMAPPGPGPAGPCLRSANTRELSEVVFNNRSPRAVLPIWVDFEGRPRYYPVLRPRTGRIMHSYRGHLWLFRDAGTHDGLLVNRQELFVAAPDVNKADITLPVFTLKERCLQVVRSLVRPGDYRKLDIVRSLYEELEDHPDVKKDLQRLSMERSKTLQEEILH", "length": 185, "header": "tr|A0A8V0Z8B2-1|A0A8V0Z8B2_CHICK Isoform 1 of von Hippel-Lindau disease tumor suppressor OS=Gallus gallus OX=9031 GN=VHL PE=3 SV=1 CANONICAL=A0A8V0Z8B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2/entry#A0A8V0Z8B2-1", "sequence": { "sequence": "MRDSLPVSGRLRARVLPSRGRAAGMAPPGPGPAGPCLRSANTRELSEVVFNNRSPRAVLPIWVDFEGRPRYYPVLRPRTGRIMHSYRGHLWLFRDAGTHDGLLVNRQELFVAAPDVNKADITLPVFTLKERCLQVVRSLVRPGDYRKLDIVRSLYEELEDHPDVKKDLQRLSMERSKTLQEEILH", "length": 185, "header": "tr|A0A8V0Z8B2-1|A0A8V0Z8B2_CHICK Isoform 1 of von Hippel-Lindau disease tumor suppressor OS=Gallus gallus OX=9031 GN=VHL PE=3 SV=1 CANONICAL=A0A8V0Z8B2-1" }, "locus": { "chromosome": "12", "start_pos": 19611937, "end_pos": 19610979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045993.1", "url": "https://www.ensembl.org/id/ENSGALT00010045993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027402.1", "url": "https://www.ensembl.org/id/ENSGALP00010027402.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P40337-1", "protein_name": "von Hippel-Lindau disease tumor suppressor", "gene_name": "VHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD", "length": 213 }, "evidence": [ { "id": "A0A8V0Z8B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40338-1", "protein_name": "von Hippel-Lindau disease tumor suppressor", "gene_name": "Vhl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRKAASPEEAAGEPGPEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPLWLNFDGEPQPYPILPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDYPSVRKDIQRLSQEHLESQHLEEEP", "length": 181 }, "evidence": [ { "id": "A0A8V0Z8B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64259-1", "protein_name": "von Hippel-Lindau disease tumor suppressor", "gene_name": "Vhl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRKAASPEEAERMPGSEEIEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPLWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVRKDIQRLTQEHLENQALGEEPEGVH", "length": 185 }, "evidence": [ { "id": "A0A8V0Z8B2", "url": "https://omabrowser.org/oma/group/A0A8V0Z8B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" }, { "name": "regulation protein catabolic process at postsynapse", "id": "GO:0140252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" }, { "id": "PF17211", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "von Hippel-Lindau disease tumour suppressor alpha", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 173, "start_aa": "Phe", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B2" }, { "id": "PF01847", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "von Hippel-Lindau disease tumour suppressor beta", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 117, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8C1-1", "uniprot_ac": "A0A8V0Z8C1", "uniprot_id": "A0A8V0Z8C1_CHICK", "mass": { "chemical_mass": 34534.0, "monoisotopic_mass": 34534.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "CH033", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTNVRTTEQKNCSGVLSFPASGQEPKLSFSFAVPKEDCPLVPLVPASQQMEGAADHEVLDNAVPTESVNMVQISALEKPELAHTASSAPREDESHVTLKISKPESAPEDNTVIEKSASERATQKKKKKKKQNASVSKKDIKETEIKRKAKVEANGCQNKGAAQQDETSQQSDDQLQKEVDWCVEQLETGLKTQKSTPKQAEEALRAIKVLRSDKAPLVKKRQIMRTIFGDYRKKMEEELCKQLKLMLSDAKSAKIEEVQNKKCQVIRRRSGALRKSQGSAGSPPESPNTPDTGAFRFTISQEEFRFNFF", "length": 310, "header": "tr|A0A8V0Z8C1-1|A0A8V0Z8C1_CHICK Isoform 1 of CH033 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z8C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C1/entry#A0A8V0Z8C1-1", "sequence": { "sequence": "MQTNVRTTEQKNCSGVLSFPASGQEPKLSFSFAVPKEDCPLVPLVPASQQMEGAADHEVLDNAVPTESVNMVQISALEKPELAHTASSAPREDESHVTLKISKPESAPEDNTVIEKSASERATQKKKKKKKQNASVSKKDIKETEIKRKAKVEANGCQNKGAAQQDETSQQSDDQLQKEVDWCVEQLETGLKTQKSTPKQAEEALRAIKVLRSDKAPLVKKRQIMRTIFGDYRKKMEEELCKQLKLMLSDAKSAKIEEVQNKKCQVIRRRSGALRKSQGSAGSPPESPNTPDTGAFRFTISQEEFRFNFF", "length": 310, "header": "tr|A0A8V0Z8C1-1|A0A8V0Z8C1_CHICK Isoform 1 of CH033 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z8C1-1" }, "locus": { "chromosome": "14", "start_pos": 13888788, "end_pos": 13886246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042161.1", "url": "https://www.ensembl.org/id/ENSGALT00010042161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024698.1", "url": "https://www.ensembl.org/id/ENSGALP00010024698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8C7-1", "uniprot_ac": "A0A8V0Z8C7", "uniprot_id": "A0A8V0Z8C7_CHICK", "mass": { "chemical_mass": 96177.0, "monoisotopic_mass": 96177.0 }, "refseq": { "ac": "NP_990023", "name": "transient receptor potential cation channel subfamily V member 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" }, "gene_names": [ { "name": "TRPV4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ] }, { "name": "TRPV4", "type": "synonym", "evidence": [ { "id": "NP_990023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ] }, { "name": "VR-OAC", "type": "synonym", "evidence": [ { "id": "NP_990023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily V member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7/entry#names_and_taxonomy" } ] }, { "name": "transient receptor potential cation channel subfamily V member 4", "type": "synonym", "evidence": [ { "id": "NP_990023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ] }, { "name": "vanilloid receptor-related osmotically activated channel protein", "type": "synonym", "evidence": [ { "id": "NP_990023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF261883.1, SRR13267656.20157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Nov 29, 2021 this sequence version replaced NP_990023.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ] }, { "annotation": "A multiligand binding site for ATP and calmodulin previously identified in the TRPV1 ankyrin repeat domain is conserved in TRPV3 and TRPV4, but not TRPV2.", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" }, { "database": "PubMed", "id": "19864432", "url": "https://glygen.org/publication/PubMed/19864432" } ] }, { "annotation": "Backbone NMR assignments of the extensive human and chicken TRPV4 N-terminal intrinsically disordered regions as important players in ion channel regulation.", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" }, { "database": "PubMed", "id": "35451798", "url": "https://glygen.org/publication/PubMed/35451798" } ] }, { "annotation": "PACSIN 3 specifically affects the endocytosis of TRPV4, thereby modulating its subcellular localization", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" }, { "database": "PubMed", "id": "16627472", "url": "https://glygen.org/publication/PubMed/16627472" } ] }, { "annotation": "TRPV4 ankyrin domain is a lipid-binding domain in which interactions with PI(4,5)P2. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" }, { "database": "PubMed", "id": "25256292", "url": "https://glygen.org/publication/PubMed/25256292" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7", "locus": { "chromosome": "15", "start_pos": 6854342, "end_pos": 6861518, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020674", "url": "https://www.ensembl.org/id/ENSGALG00010020674" } ] } } ], "crossref": [ { "id": "A0A8V0Z8C7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8C7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395427", "url": "https://www.ncbi.nlm.nih.gov/gene/395427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395427", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395427", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIHSALY", "url": "https://omabrowser.org/oma/group/MIHSALY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPEDPRDAGDVLGDDSFPLSSLANLFEVEDTPSPAEPSRGPPGAGDGKQNLRMKFHGAFRKGPPKPMELLESTIYESSVVPAPKKAPMDSLFDYGTYRQHPSENKRWRRRVVEKPVAGTKGPAPNPPPILKVFNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRREIADEDVRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLCDKWRKFGAVSFYISVVSYLCAMIIFTLIAYYRPMEGPPPYPYTTTIDYLRLAGEIITLLTGILFFFSNIKDLFMKKCPGVNSFFIDGSFQLLYFIYSVLVIVTAGLYLGGVEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCPSSESCSEDHSNCTLPTYPSCRDSQTFSTFLLDLFKLTIGMGDLEMLESAKYPGVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPLFLRRAFRSGEMVTVGKGTDGTPDRRWCFRVDEVNWSHWNQNMGIISEDPGKSDTYQYYGFSHTVGRLRRDRWSTVVPRVVELNKSCPTEDVVVPLGTMGTAEARERRHGQTPSSPL", "length": 852, "header": "tr|A0A8V0Z8C7-1|A0A8V0Z8C7_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 4 OS=Gallus gallus OX=9031 GN=TRPV4 PE=4 SV=1 CANONICAL=A0A8V0Z8C7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7/entry#A0A8V0Z8C7-1", "sequence": { "sequence": "MADPEDPRDAGDVLGDDSFPLSSLANLFEVEDTPSPAEPSRGPPGAGDGKQNLRMKFHGAFRKGPPKPMELLESTIYESSVVPAPKKAPMDSLFDYGTYRQHPSENKRWRRRVVEKPVAGTKGPAPNPPPILKVFNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRREIADEDVRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLCDKWRKFGAVSFYISVVSYLCAMIIFTLIAYYRPMEGPPPYPYTTTIDYLRLAGEIITLLTGILFFFSNIKDLFMKKCPGVNSFFIDGSFQLLYFIYSVLVIVTAGLYLGGVEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCPSSESCSEDHSNCTLPTYPSCRDSQTFSTFLLDLFKLTIGMGDLEMLESAKYPGVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPLFLRRAFRSGEMVTVGKGTDGTPDRRWCFRVDEVNWSHWNQNMGIISEDPGKSDTYQYYGFSHTVGRLRRDRWSTVVPRVVELNKSCPTEDVVVPLGTMGTAEARERRHGQTPSSPL", "length": 852, "header": "tr|A0A8V0Z8C7-1|A0A8V0Z8C7_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 4 OS=Gallus gallus OX=9031 GN=TRPV4 PE=4 SV=1 CANONICAL=A0A8V0Z8C7-1" }, "locus": { "chromosome": "15", "start_pos": 6859708, "end_pos": 6854652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049942.1", "url": "https://www.ensembl.org/id/ENSGALT00010049942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029497.1", "url": "https://www.ensembl.org/id/ENSGALP00010029497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Cuajungco MP, Grimm C, Oshima K, D'hoedt D, Nilius B, Mensenkamp AR, Bindels RJ, Plomann M, Heller S", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ], "reference": [ { "type": "PubMed", "id": "16627472", "url": "https://glygen.org/publication/PubMed/16627472" } ] }, { "title": "Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.", "journal": "The Journal of biological chemistry", "date": "2010-01-01", "authors": "Phelps Christopher B, Wang Ruiqi R, Choo Shelly S, Gaudet Rachelle", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ], "reference": [ { "type": "PubMed", "id": "19864432", "url": "https://glygen.org/publication/PubMed/19864432" } ] }, { "title": "TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P(2).", "journal": "Nature communications", "date": "2014", "authors": "Takahashi N, Hamada-Nakahara S, Itoh Y, Takemura K, Shimada A, Ueda Y, Kitamata M, Matsuoka R, Hanawa-Suetsugu K, Senju Y, Mori MX, Kiyonaka S, Kohda D, Kitao A, Mori Y, Suetsugu S", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ], "reference": [ { "type": "PubMed", "id": "25256292", "url": "https://glygen.org/publication/PubMed/25256292" } ] }, { "title": "Backbone NMR assignments of the extensive human and chicken TRPV4 N-terminal intrinsically disordered regions as important players in ion channel regulation.", "journal": "Biomolecular NMR assignments", "date": "2022-10", "authors": "Goretzki Benedikt, Tebbe Frederike, Mitrovic Sarah-Ana, Hellmich Ute A", "evidence": [ { "database": "RefSeq", "id": "NP_990023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990023" } ], "reference": [ { "type": "PubMed", "id": "35451798", "url": "https://glygen.org/publication/PubMed/35451798" } ] } ], "pathway": [ { "id": "gga:395427", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395427", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9ERZ8-1", "protein_name": "Transient receptor potential cation channel subfamily V member 4", "gene_name": "Trpv4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGDGPRAAPGDVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDNKRWRRKVVEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLSYLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDSNLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLLTGVLFFFTSIKDLFMKKCPGVNSLFVDGSFQLLYFIYSVLVVVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVTLLNPCTNMKVCNEDQSNCTVPSYPACRDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGKSEIYQYYGFSHTMGRLRRDRWSSVVPRVVELNKNSGTDEVVVPLDNLGNPNCDGHQQGYAPKWRAEDAPL", "length": 871 }, "evidence": [ { "id": "A0A8V0Z8C7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HBA0-1", "protein_name": "Transient receptor potential cation channel subfamily V member 4", "gene_name": "TRPV4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDNKRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL", "length": 871 }, "evidence": [ { "id": "A0A8V0Z8C7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8C7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 26, "go_terms": [ { "name": "osmosensory signaling pathway", "id": "GO:0007231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007231", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "diet induced thermogenesis", "id": "GO:0002024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "regulation of aerobic respiration", "id": "GO:1903715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903715", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of monocyte chemotactic protein-1 production", "id": "GO:0071639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071639", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "multicellular organismal-level water homeostasis", "id": "GO:0050891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "cartilage development involved in endochondral bone morphogenesis", "id": "GO:0060351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of chemokine (C-C motif) ligand 5 production", "id": 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"" }, { "name": "cellular hypotonic salinity response", "id": "GO:0071477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of macrophage inflammatory protein 1 alpha production", "id": "GO:0071642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "positive regulation of chemokine (C-X-C motif) ligand 1 production", "id": "GO:2000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C7" } ], "pmid": "" }, { "name": "blood vessel endothelial cell delamination", "id": "GO:0097497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097497", "evidence": [ { 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"gene_names": [ { "name": "LRR1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8" } ] }, { "name": "LRR1", "type": "synonym", "evidence": [ { "id": "XP_421455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421455" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421455" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421455.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421455" } ] }, { "annotation": "Substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase. May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X3#function" }, { "database": "UniProtKB", "id": "ARBA00053478", "url": "https://www.uniprot.org/uniprotkb/ARBA00053478#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8#function" }, { "database": "UniProtKB", "id": "A0A8V0Z914", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z914#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRR1", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z914", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z914", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z914-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z914-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLQCDVEVVSRLLPTCGLRGRGRGTRALLSLGRQPGRARGGVCLMVCTARDRAGVRYQVQDNVERFFTRFVEEGKATVRLKEPAVDVCLSKANASNLKTFLSAVRLAHQGSDVAALPLSALVPAKTSEVEKPKTKMIITSKRDYPLTKGFPYSLEHLQASYCRLARIDTRVLCLKKLRKLDLSHNHIKQLPATIGDLLFLQELNLHDNHLESFSSALCSSTLQKSLQCLDLSQNKIKALPIQFCQLRELVNLKLDDNELIRLPFKIGQLDHLRFLSAARNKLPFLPSDFRKLCLENLDLFGNPFEQPNPLLPNIQLKIPLTLLECAARATVNYRIPYGHQLLPSHLCEDLEVAKTCQCGSACLSSFIQITVTMNLHHVAHTVVLVDNMGGTEAPIICYFCSLGCYSQFLDRYLQSSADH", "length": 420, "header": "tr|A0A8V0Z8F8-1|A0A8V0Z8F8_CHICK Isoform 1 of Leucine-rich repeat protein 1 OS=Gallus gallus OX=9031 GN=LRR1 PE=4 SV=1 CANONICAL=A0A8V0Z8F8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8/entry#A0A8V0Z8F8-1", "sequence": { "sequence": "MRLQCDVEVVSRLLPTCGLRGRGRGTRALLSLGRQPGRARGGVCLMVCTARDRAGVRYQVQDNVERFFTRFVEEGKATVRLKEPAVDVCLSKANASNLKTFLSAVRLAHQGSDVAALPLSALVPAKTSEVEKPKTKMIITSKRDYPLTKGFPYSLEHLQASYCRLARIDTRVLCLKKLRKLDLSHNHIKQLPATIGDLLFLQELNLHDNHLESFSSALCSSTLQKSLQCLDLSQNKIKALPIQFCQLRELVNLKLDDNELIRLPFKIGQLDHLRFLSAARNKLPFLPSDFRKLCLENLDLFGNPFEQPNPLLPNIQLKIPLTLLECAARATVNYRIPYGHQLLPSHLCEDLEVAKTCQCGSACLSSFIQITVTMNLHHVAHTVVLVDNMGGTEAPIICYFCSLGCYSQFLDRYLQSSADH", "length": 420, "header": "tr|A0A8V0Z8F8-1|A0A8V0Z8F8_CHICK Isoform 1 of Leucine-rich repeat protein 1 OS=Gallus gallus OX=9031 GN=LRR1 PE=4 SV=1 CANONICAL=A0A8V0Z8F8-1" }, "locus": { "chromosome": "5", "start_pos": 57357877, "end_pos": 57352126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046047.1", "url": "https://www.ensembl.org/id/ENSGALT00010046047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027443.1", "url": "https://www.ensembl.org/id/ENSGALP00010027443.1" } ] } }, { "isoform_ac": "A0A8V0Z914-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8/entry#A0A8V0Z914-1", "sequence": { "sequence": "MRLQCDVEVVSRLLPTCGLRGRGRGTRALLSLGRQPGRARGGVCLMVCTARDRAGVRYQANASNLKTFLSAVRLAHQGSDVAALPLSALVPAKTSEVEKPKTKMIITSKRDYPLTKGFPYSLEHLQASYCRLARIDTRVLCLKKLRKLDLSHNHIKQLPATIGDLLFLQELNLHDNHLESFSSALCSSTLQKSLQCLDLSQNKIKALPIQFCQLRELVNLKLDDNELIRLPFKIGQLDHLRFLSAARNKLPFLPSDFRKLCLENLDLFGNPFEQPNPLLPNIQLKIPLTLLECAARATVNYRIPYGHQLLPSHLCEDLEVAKTCQCGSACLSSFIQITVTMNLHHVAHTVVLVDNMGGTEAPIICYFCSLGCYSQFLDRYLQSSADH", "length": 387, "header": "tr|A0A8V0Z914-1|A0A8V0Z914_CHICK Computationally mapped isoform of Leucine-rich repeat protein 1 OS=Gallus gallus OX=9031 GN=LRR1 PE=4 SV=1 CANONICAL=A0A8V0Z8F8-1" }, "locus": { "chromosome": "5", "start_pos": 57357877, "end_pos": 57352126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046050.1", "url": "https://www.ensembl.org/id/ENSGALT00010046050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027445.1", "url": "https://www.ensembl.org/id/ENSGALP00010027445.1" } ] } }, { "isoform_ac": "A0A8V0Z9X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8/entry#A0A8V0Z9X3-1", "sequence": { "sequence": "MRLQCDPGRARGGVCLMVCTARDRAGVRYQVQDNVERFFTRFVEEGKATVRLKEPAVDVCLSKANASNLKTFLSAVRLAHQGSDVAALPLSALVPAKTSEVEKPKTKMIITSKRDYPLTKGFPYSLEHLQASYCRLARIDTRVLCLKKLRKLDLSHNHIKQLPATIGDLLFLQELNLHDNHLESFSSALCSSTLQKSLQCLDLSQNKIKALPIQFCQLRELVNLKLDDNELIRLPFKIGQLDHLRFLSAARNKLPFLPSDFRKLCLENLDLFGNPFEQPNPLLPNIQLKIPLTLLECAARATVNYRIPYGHQLLPSHLCEDLEVAKTCQCGSACLSSFIQITVTMNLHHVAHTVVLVDNMGGTEAPIICYFCSLGCYSQFLDRYLQSSADH", "length": 391, "header": "tr|A0A8V0Z9X3-1|A0A8V0Z9X3_CHICK Computationally mapped isoform of Leucine-rich repeat protein 1 OS=Gallus gallus OX=9031 GN=LRR1 PE=4 SV=1 CANONICAL=A0A8V0Z8F8-1" }, "locus": { "chromosome": "5", "start_pos": 57357877, "end_pos": 57352126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046042.1", "url": "https://www.ensembl.org/id/ENSGALT00010046042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027439.1", "url": "https://www.ensembl.org/id/ENSGALP00010027439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423565", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3YY91-1", "protein_name": "Leucine-rich repeat protein 1", "gene_name": "Lrr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLPCEVEVRSCHLPTLGLKSRGKGVRAVVSLCQAPGRNELQPEARAEPGGHACLLVSTMKDRQGTSYKLRENIEQLFTKFVDEGKATVRLKEPPVDICLSKANPGNLKTLLSAMRLAHRGCDVNTPLSTLKPVKTSEFEKYKTKMVITSKKDYPLSKNFPYFLEHLQASYCSLARVDMRMLCLKNLTKLDLSHNCIKKLPATIGDLTHLQELNLNDNQLETFSVPLCTSTLQKSLHSLDLSKNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGQLTNLRFLSAARNKLRNLPSEFKMLSLEYLDLFGNTFEKPEVIPIIKLQVPLTLLESCEQAVLFYRIPYGPDIIPYHLCQDLDTAKTCVCGRFCLQSFIQGTTTMNLHSVAHTVVLVDSMGRTEAPVVSYFCSLTCFVKSSDMLN", "length": 422 }, "evidence": [ { "id": "A0A8V0Z8F8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZE86-1", "protein_name": "Leucine-rich repeat protein 1", "gene_name": "Lrr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLPCEVEVRSCHLPTLGLKSRGKGVRAVVSLCQAPSKNELQPGARTETSGCACLLVSTMKDRQGTRYRLRENIEQLFTKFVDEGKATVRLKEPPVDICLSKANPGNLKTFLSAMRLAHRGSDVNTPLSTLKPVKTSEFEKFKTKMIITSKKDYPLSKNFPYSLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFSVPLCKSTLQKSLQSLDLSKNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEKPEVLPIINLQVPLTLLEACEQAVLSYRIPYGPDIIPYHLCQDLDTAKTCVCGRFCLQSFIQGTTTMNLHSLAHTVVLIDTMGRMEAPIISYFCSLTCFVNSSDMLK", "length": 422 }, "evidence": [ { "id": "A0A8V0Z8F8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96L50-1", "protein_name": "Leucine-rich repeat protein 1", "gene_name": "LRR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPVSTLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVIKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK", "length": 414 }, "evidence": [ { "id": "A0A8V0Z8F8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKU0-1", "protein_name": "Leucine-rich repeat 47, isoform B", "gene_name": "Lrr47", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKILCEVQVVNRATQTNKTPRPVKSTLAIGYKQSARDANGNTKKELEMVLFSGQNKTGNRYKVKDNIHVVHTKFVLDGKTTIGFIQPPDNLLIKCDPIQLKGFLQTLKLGMDGKDAINLRLNINAATAIPQKAQPQVRMVISKRSEYPIKGFPRTLKSLTINNSQLVKLSFEICTLRNLTKLDVSGNKLTKIPSELGRLPLTSLHLGNNLLGTQNDWCWLRGTKLCQSLGELDLSGNGLTYFPPPLVKFESLVSLNLNNNLLSRLPFAIRRMKALRKLYVCSNELESLPSAVEDLRIDLLDVWGNCFKEFNADAAQQMYLQKAASNSPQPLWLLGARAVDKYMLPLSAGSIPAVLIDLIREAPRCPCGELCYAQRKEDLFQRVVQPKFITVKNLTYSREHQIYADVVLCDSRCSASAELKLLFNIIFS", "length": 428 }, "evidence": [ { "id": "A0A8V0Z8F8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8F8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8F8" }, { "id": "PF25344", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25344" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIF1/LRR1 pleckstrin homology", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 119, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8G2-1", "uniprot_ac": "A0A8V0Z8G2", "uniprot_id": "A0A8V0Z8G2_CHICK", "mass": { "chemical_mass": 150376.0, "monoisotopic_mass": 150376.0 }, "refseq": { "ac": "NP_001186368", "name": "tau-tubulin kinase 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186368" }, "gene_names": [ { "name": "TTBK1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "name": "TTBK1", "type": "synonym", "evidence": [ { "id": "NP_001186368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186368" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2/entry#names_and_taxonomy" } ] }, { "name": "tau-tubulin kinase 1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001186368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186368" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA103992290, SAMEA103992393 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000062.1. On Dec 1, 2021 this sequence version replaced NP_001186368.1. Transcript Variant: This variant (1) has 16 exons. The genome location has 22 possible exons. The 5' UTR has the first seven in various alternative splicing combinations. The remainder are the CDS and the 3' UTR. This transcript has exons 7 plus exons 8 through 22. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186368", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186368" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTBK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2", "locus": { "chromosome": "3", "start_pos": 15668947, "end_pos": 15586526, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018909", "url": "https://www.ensembl.org/id/ENSGALG00010018909" } ] } } ], "crossref": [ { "id": "cd14130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416713", "url": "https://www.ncbi.nlm.nih.gov/gene/416713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416713", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8G2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8G6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186368", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186368", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVSAKRMHGLSSGVCEINGSFKLGATKILSGWQMQCLAAVIKDEPNMSGGGEQVDILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGITENEAFDWEKAGTDILLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILSGRPAEGLGQTPNTAFNEAEVWEETDVNRNKLRISISKTQCMVEEDQRNGVCPSSPVRVPPESPTAQARSLRYRRVNSPESERLSTADGKADLHERRSRMDLPGSPSRLVCSSQPAQMLSIDTGQVDRQASGRMDVSASVEHEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFHPGAEPSTSGTTDEEPEELRPIEDGEERRRLGADAAVRPKTHDGRSRGMQPVTEEDSSHRHEGPSQTVSDSKHEQQTGSPAHSPLHSAPAIRQRRRESEPTGPQRQAFSALPPESFEMNGLPKAVPLSLPYQDFRKDMLDYWEKAKLSQRIKRVDFSNVVLTAPCKPLEPYLEMNGKEEEEEDEEEDEDEEEDEEDVEEEGDEIDMHSGSSSDLSQKSTERSQECAPSTLLADDQKGSKGRASMADGDLELEEGSKTLVLFSPGDLKKSPVTTDLPPEVDLGTLAALTPQSERPQPMGSQLDVSEPGTLSSVLKSEPKPPVAVATASSPFTKVERTFVHIAEKTHLNVMSSSGQLMRHEEYCPPGQFEEVIIEEELEDNLVLVENGSIHSGLEGAETESCALSANPIETTSETVGEQLSVPNVAKPPEDKAESSDNVALSLDLEESAKVVTREPDLEKPASVAEHLKPAGTLPDAPQQGPRRPLGSRYRSRIPILFSEEDTGSDLSTSLSAKERLYKRAKQPDLARLVMEKRQNCLLRLASGASSSASSSDERRRASETLSATGSEEDTHDSDDSIPRKAGKKAALLGREEKLISTKSRIPRPITPVKTPLETMKSESSTAVVMAVLSSSPQDAAVAYRLQAQRPAGSVPNDCRTTQIQSRLPPSPSSTSLPPRSSTQRSSCASPRSPVLPSKTPSASPRSQLLPRRESPSPCRQHKPGTALQRVPPSPRPQPQAQALGPTGDSLPSPGMAKKRQRGKTQTQSPATKGKQVSLESKATAR", "length": 1365, "header": "tr|A0A8V0Z8G2-1|A0A8V0Z8G2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK1 PE=3 SV=1 CANONICAL=A0A8V0Z8G2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2/entry#A0A8V0Z8G2-1", "sequence": { "sequence": "MVVSAKRMHGLSSGVCEINGSFKLGATKILSGWQMQCLAAVIKDEPNMSGGGEQVDILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGITENEAFDWEKAGTDILLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILSGRPAEGLGQTPNTAFNEAEVWEETDVNRNKLRISISKTQCMVEEDQRNGVCPSSPVRVPPESPTAQARSLRYRRVNSPESERLSTADGKADLHERRSRMDLPGSPSRLVCSSQPAQMLSIDTGQVDRQASGRMDVSASVEHEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFHPGAEPSTSGTTDEEPEELRPIEDGEERRRLGADAAVRPKTHDGRSRGMQPVTEEDSSHRHEGPSQTVSDSKHEQQTGSPAHSPLHSAPAIRQRRRESEPTGPQRQAFSALPPESFEMNGLPKAVPLSLPYQDFRKDMLDYWEKAKLSQRIKRVDFSNVVLTAPCKPLEPYLEMNGKEEEEEDEEEDEDEEEDEEDVEEEGDEIDMHSGSSSDLSQKSTERSQECAPSTLLADDQKGSKGRASMADGDLELEEGSKTLVLFSPGDLKKSPVTTDLPPEVDLGTLAALTPQSERPQPMGSQLDVSEPGTLSSVLKSEPKPPVAVATASSPFTKVERTFVHIAEKTHLNVMSSSGQLMRHEEYCPPGQFEEVIIEEELEDNLVLVENGSIHSGLEGAETESCALSANPIETTSETVGEQLSVPNVAKPPEDKAESSDNVALSLDLEESAKVVTREPDLEKPASVAEHLKPAGTLPDAPQQGPRRPLGSRYRSRIPILFSEEDTGSDLSTSLSAKERLYKRAKQPDLARLVMEKRQNCLLRLASGASSSASSSDERRRASETLSATGSEEDTHDSDDSIPRKAGKKAALLGREEKLISTKSRIPRPITPVKTPLETMKSESSTAVVMAVLSSSPQDAAVAYRLQAQRPAGSVPNDCRTTQIQSRLPPSPSSTSLPPRSSTQRSSCASPRSPVLPSKTPSASPRSQLLPRRESPSPCRQHKPGTALQRVPPSPRPQPQAQALGPTGDSLPSPGMAKKRQRGKTQTQSPATKGKQVSLESKATAR", "length": 1365, "header": "tr|A0A8V0Z8G2-1|A0A8V0Z8G2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK1 PE=3 SV=1 CANONICAL=A0A8V0Z8G2-1" }, "locus": { "chromosome": "3", "start_pos": 15667943, "end_pos": 15591530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045732.1", "url": "https://www.ensembl.org/id/ENSGALT00010045732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027259.1", "url": "https://www.ensembl.org/id/ENSGALP00010027259.1" } ] } }, { "isoform_ac": "A0A8V0Z8G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2/entry#A0A8V0Z8G6-1", "sequence": { "sequence": "MINGSFKLGATKILSGWQMQCLAAVIKDEPNMSGGGEQVDILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGITENEAFDWEKAGTDILLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILSGRPAEGLGQTPNTAFNEAEVWEETDVNRNKLRISISKTQCMVEEDQRNGVCPSSPVRVPPESPTAQARSLRYRRVNSPESERLSTADGKADLHERRSRMDLPGSPSRLVCSSQPAQMLSIDTGQVDRQASGRMDVSASVEHEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFHPGAEPSTSGTTDEEPEELRPIEDGEERRRLGADAAVRPKTHDGRSRGMQPVTEEDSSHRHEGPSQTVSDSKHEQQTGSPAHSPLHSAPAIRQRRRESEPTGPQRQAYTLKSFEMNGLPKAVPLSLPYQDFRKDMLDYWEKAKLSQRIKRVDFSNVVLTAPCKPLEPYLEMNGKEEEEEDEEEDEDEEEDEEDVEEEGDEIDMHSGSSSDLSQKSTERSQECAPSTLLADDQKGSKGRASMADGDLELEEGSKTLVLFSPGDLKKSPVTTDLPPEVDLGTLAALTPQSERPQPMGSQLDVSEPGTLSSVLKSEPKPPVAVATASSPFTKVERTFVHIAEKTHLNVMSSSGQLMRHEEYCPPGQFEEVIIEEELEDNLVLVENGSIHSGLEGAETESCALSANPIETTSETVGEQLSVPNVAKPPEDKAESSDNVALSLDLEESAKVVTREPDLEKPASVAEHLKPAGTLPDAPQQGPRRPLGSRYRSRIPILFSEEDTGSDLSTSLSAKERLYKRAKQPDLARLVMEKRQNCLLRLASGASSSASSSDERRRASETLSATGSEEDTHDSDDSIPRKAGKKAALLGREEKLISTKSRIPRPITPVKTPLETMKSESSTAVVMAVLSSSPQDAAVAYRLQAQRPAGSVPNDCRTTQIQSRLPPSPSSTSLPPRSSTQRSSCASPRSPVLPSKTPSASPRSQLLPRRESPSPCRQHKPGTALQRVPPSPRPQPQAQALGPTGDSLPSPGMAKKRQRGKTQTQSPATKGKQVSLESKATAR", "length": 1346, "header": "tr|A0A8V0Z8G6-1|A0A8V0Z8G6_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK1 PE=3 SV=1 CANONICAL=A0A8V0Z8G2-1" }, "locus": { "chromosome": "3", "start_pos": 15667943, "end_pos": 15587534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045740.1", "url": "https://www.ensembl.org/id/ENSGALT00010045740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027264.1", "url": "https://www.ensembl.org/id/ENSGALP00010027264.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416713", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416713", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "tau protein binding", "id": "GO:0048156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "positive regulation of microglial cell activation", "id": "GO:1903980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903980", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" }, { "name": "positive regulation of protein polymerization", "id": "GO:0032273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", 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"id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { 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[ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q9I9E0", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] } ] }, { "uniprot_ac": "Q9IA88", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 331, "start_aa": "Trp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9W1-1", "uniprot_ac": "A0A8V0Z9W1", "uniprot_id": "A0A8V0Z9W1_CHICK", "mass": { "chemical_mass": 119594.0, "monoisotopic_mass": 119594.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHG5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ] } ], "protein_names": [ { "name": "Pleckstrin homology and RhoGEF domain containing G5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1", "locus": { "chromosome": "21", "start_pos": 590479, "end_pos": 577926, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019016", "url": "https://www.ensembl.org/id/ENSGALG00010019016" } ] } } ], "crossref": [ { "id": "A0A8V0Z9W1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9W1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426013", "url": "https://www.ncbi.nlm.nih.gov/gene/426013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426013", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8G3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9V6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9W1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13217", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13217", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13217:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13217:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLLWAACTRNGPGTLGQGAGGSWSQHCECTLLFSAGEAGATVLDEQCPAEEQGLRCQNPDCTDKRRAAKVCHHAECQQLNRSSPLSLCEACDGHLHGTMHFDGHIRFDLPPPGSILARNVSTRSCPPRTSPASDVEDDDEGPADGRGDRRSSALKLPKKKARRRHTDDPSKECFTLKFDLNVDIEAEIVPAMKKKSLGDVLLPVFERRAIEQSKVDIYLDQSNTPLSLQFEAYRFGGHYLRVKAKPGDELKVEQAARDARSASLPILRPAGTAALLGTGLESGPGRREGTDILAPGRRRKNMTEFLGDANIPSPEPSLHGSGSLPTNGTDTWKNRAASRFSGFFSSGASTGPFGREVDKMEQLESKLHTYSSFGLPKLPPQLRFDQDSWEEDGDDSSLVLEDSWQQIIEGAEALTRRQCHQQEAIWELLHTEATYIRKLKVITDLFLCCLLNLQESGLLCEVDAERLFGNIGEIIQLHRSLWSSVMAPVLDKARRTKVLLDPMDFLKGFKMFGTLFKPYIQYCMEEEGCMEYMRTLLRDSELFRAYVTWAEKHKQCSRLKLSDMLVKPHQRLTKYPLLLKSVLKKTDDARTRDAILTMIGSVEHFINHVNSRMRQRQEQQRLAAILSRIDAYEVVEGSTDEVDKLLKEFLRLDLTAPMPGTSPDDTRQLLLEGSLKMREGKDSKMDVYCFLFTDLFLITKPVKKAERTKVVRQPLLVDKVVCRELKDPGSFLLIYLNEFGSAVAAYTFQASGQSLCRSWVEALHNAQNLLQRLRLQEQQRGQCRRLQEEEEDEEDGESSTSTASSPTVLRRSSTSLDSQQCPSDGSTETISVVVVDGGNELSSPDLDVGPFGSPSDSTSVSTGTSVSTATGTSGSTPTHELPSGSLPLPHGVTAQPGSCCSASIDSAYGTLSPASPRDFPRQQDVGAEEGPEALAPRPPSPRLRRRTPVQLLPCKARVLKSKSEASLLQLLAGPPAPLSQSRSLSDLCMAPPVPSLLQRTSHAPGHPAPSAGSSSSGDSASELSEPEEPMESPVPTLGQPGHSPQPPAHRMLSDSSSVQHRKLTLAQLYRIRTTLLLNSTLTASEV", "length": 1088, "header": "tr|A0A8V0Z9W1-1|A0A8V0Z9W1_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G5 OS=Gallus gallus OX=9031 GN=PLEKHG5 PE=4 SV=1 CANONICAL=A0A8V0Z9W1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1/entry#A0A8V0Z8G3-1", "sequence": { "sequence": "MHFDGHIRFDLPPPGSILARNVSTRSCPPRTSPASDVEDDDEGPADGRGDRRSSALKLPKKKARRRHTDDPSKECFTLKFDLNVDIEAEIVPAMKKKSLGDVLLPVFERRAIEQSKVDIYLDQSNTPLSLQFEAYRFGGHYLRVKAKPGDELKVEQAARDARSASLPILRPAGTAALLGTGLESGPGRREGTDILAPGRRRKNMTEFLGDANIPSPEPSLHGSGSLPTNGTDTWKNRAASRFSGFFSSGASTGPFGRQEVDKMEQLESKLHTYSSFGLPKLPPQLRFDQDSWEEDGDDSSLVLEDSWQQIIEGAEALTRRQCHQQEAIWELLHTEATYIRKLKVITDLFLCCLLNLQESGLLCEVDAERLFGNIGEIIQLHRSLWSSVMAPVLDKARRTKVLLDPMDFLKGFKMFGTLFKPYIQYCMEEEGCMEYMRTLLRDSELFRAYVTWAEKHKQCSRLKLSDMLVKPHQRLTKYPLLLKSVLKKTDDARTRDAILTMIGSVEHFINHVNSRMRQRQEQQRLAAILSRIDAYEVVEGSTDEVDKLLKEFLRLDLTAPMPGTSPDDTRQLLLEGSLKMREGKDSKMDVYCFLFTDLFLITKPVKKAERTKVVRQPLLVDKVVCRELKDPGSFLLIYLNEFGSAVAAYTFQASGQSLCRSWVEALHNAQVKTWCGGDAGISCPQPPDTCHPQNLLQRLRLQEQQRGQCRRLQEEEEDEEDGESSTSTASSPTVLRRSSTSLDSQQWYEWDGGTVTVPAAQPPPHLLLSCSPSDGSTETISVVVVDGGNELSSPDLDVGPFGSPSDSTSVSTGTSVSTATGTSGSTPTHELPSGSLPLPHGVTAQPGSCCSASIDSAYGTLSPASPRDFPRQQDVGAEEGPEALAPRPPSPRLRRRTPVQLLPCKARVLKSKSEASLLQLLAGPPAPLSQSRSLSDLCMAPPVPSLLQRTSHAPGHPAPSAGSSSSGDSASELSEPEEPMESPVPTLGQPGHSPQPPAHRMLSDSSSVQHRKLTLAQLYRIRTTLLLNSTLTASEV", "length": 1036, "header": "tr|A0A8V0Z8G3-1|A0A8V0Z9W1_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G5 OS=Gallus gallus OX=9031 GN=PLEKHG5 PE=4 SV=1 CANONICAL=A0A8V0Z9W1-1" }, "locus": { "chromosome": "21", "start_pos": 589741, "end_pos": 583709, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046054.1", "url": "https://www.ensembl.org/id/ENSGALT00010046054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027448.1", "url": "https://www.ensembl.org/id/ENSGALP00010027448.1" } ] } }, { "isoform_ac": "A0A8V0Z9V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1/entry#A0A8V0Z9V6-1", "sequence": { "sequence": "MVCHHAECQQLNRSSPLSLCEACDGHLHGTMHFDGHIRFDLPPPGSILARNVSTRSCPPRTSPASDVEDDDEGPADGRGDRRSSALKLPKKKARRRHTDDPSKECFTLKFDLNVDIEAEIVPAMKKKSLGDVLLPVFERRAIEQSKVDIYLDQSNTPLSLQFEAYRFGGHYLRVKAKPGDELKVEQAARDARSASLPILRPAGTAALLGTGLESGPGRREGTDILAPGRRRKNMTEFLGDANIPSPEPSLHGSGSLPTNGTDTWKNRAASRFSGFFSSGASTGPFGRQEVDKMEQLESKLHTYSSFGLPKLPPQLRFDQDSWEEDGDDSSLVLEDSWQQIIEGAEALTRRQCHQQEAIWELLHTEATYIRKLKVITDLFLCCLLNLQESGLLCEVDAERLFGNIGEIIQLHRSLWSSVMAPVLDKARRTKVLLDPMDFLKGFKMFGTLFKPYIQYCMEEEGCMEYMRTLLRDSELFRAYVTWAEKHKQCSRLKLSDMLVKPHQRLTKYPLLLKSVLKKTDDARTRDAILTMIGSVEHFINHVNSRMRQRQEQQRLAAILSRIDAYEVVEGSTDEVDKLLKEFLRLDLTAPMPGTSPDDTRQLLLEGSLKMREGKDSKMDVYCFLFTDLFLITKPVKKAERTKVVRQPLLVDKVVCRELKDPGSFLLIYLNEFGSAVAAYTFQASGQSLCRSWVEALHNAQNLLQRLRLQEQQRGQCRRLQEEEEDEEDGESSTSTASSPTVLRRSSTSLDSQQCPSDGSTETISVVVVDGGNELSSPDLDVGPFGSPSDSTSVSTGTSVSTATGTSGSTPTHELPSGSLPLPHGVTAQPGSCCSASIDSAYGTLSPASPRDFPRQQDVGAEEGPEALAPRPPSPRLRRRTPVQLLPCKARVLKSKSEASLLQLLAGPPAPLSQSRSLSDLCMAPPVPSLLQRTSHAPGHPAPSAGSSSSGDSASELSEPEEPMESPVPTLGQPGHSPQPPAHRMLSDSSSVQHRKLTLAQLYRIRTTLLLNSTLTASEV", "length": 1019, "header": "tr|A0A8V0Z9V6-1|A0A8V0Z9V6_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G5 OS=Gallus gallus OX=9031 GN=PLEKHG5 PE=4 SV=1 CANONICAL=A0A8V0Z9W1-1" }, "locus": { "chromosome": "21", "start_pos": 589741, "end_pos": 582232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046026.1", "url": "https://www.ensembl.org/id/ENSGALT00010046026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027423.1", "url": "https://www.ensembl.org/id/ENSGALP00010027423.1" } ] } }, { "isoform_ac": "A0A8V0Z9W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1/entry#A0A8V0Z9W1-1", "sequence": { "sequence": 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"length": 1088, "header": "tr|A0A8V0Z9W1-1|A0A8V0Z9W1_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G5 OS=Gallus gallus OX=9031 GN=PLEKHG5 PE=4 SV=1 CANONICAL=A0A8V0Z9W1-1" }, "locus": { "chromosome": "21", "start_pos": 589741, "end_pos": 580824, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046032.1", "url": "https://www.ensembl.org/id/ENSGALT00010046032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027429.1", "url": "https://www.ensembl.org/id/ENSGALP00010027429.1" } ] } }, { "isoform_ac": "A0A8V0ZFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1/entry#A0A8V0ZFV3-1", "sequence": { "sequence": "MFLYWKKRGAYELGALPPALAGMEYGAVERFSWSSSLDISEQLADEQCPAEEQGLRCQNPDCTDKRRAAKVCHHAECQQLNRSSPLSLCEACDGHLHGTMHFDGHIRFDLPPPGSILARNVSTRSCPPRTSPASDVEDDDEGPADGRGDRRSSALKLPKKKARRRHTDDPSKECFTLKFDLNVDIEAEIVPAMKKKSLGDVLLPVFERRAIEQSKVDIYLDQSNTPLSLQFEAYRFGGHYLRVKAKPGDELKVEQAARDARSASLPILRPAGTAALLGTGLESGPGRREGTDILAPGRRRKNMTEFLGDANIPSPEPSLHGSGSLPTNGTDTWKNRAASRFSGFFSSGASTGPFGRQEVDKMEQLESKLHTYSSFGLPKLPPQLRFDQDSWEEDGDDSSLVLEDSWQQIIEGAEALTRRQCHQQEAIWELLHTEATYIRKLKVITDLFLCCLLNLQESGLLCEVDAERLFGNIGEIIQLHRSLWSSVMAPVLDKARRTKVLLDPMDFLKGFKMFGTLFKPYIQYCMEEEGCMEYMRTLLRDSELFRAYVTWAEKHKQCSRLKLSDMLVKPHQRLTKYPLLLKSVLKKTDDARTRDAILTMIGSVEHFINHVNSRMRQRQEQQRLAAILSRIDAYEVVEGSTDEVDKLLKEFLRLDLTAPMPGTSPDDTRQLLLEGSLKMREGKDSKMDVYCFLFTDLFLITKPVKKAERTKVVRQPLLVDKVVCRELKDPGSFLLIYLNEFGSAVAAYTFQASGQSLCRSWVEALHNAQNLLQRLRLQEQQRGQCRRLQEEEEDEEDGESSTSTASSPTVLRRSSTSLDSQQCPSDGSTETISVVVVDGGNELSSPDLDVGPFGSPSDSTSVSTGTSVSTATGTSGSTPTHELPSGSLPLPHGVTAQPGSCCSASIDSAYGTLSPASPRDFPRQQDVGAEEGPEALAPRPPSPRLRRRTPVQLLPCKARVLKSKSEASLLQLLAGPPAPLSQSRSLSDLCMAPPVPSLLQRTSHAPGHPAPSAGSSSSGDSASELSEPEEPMESPVPTLGQPGHSPQPPAHRMLSDSSSVQHRKLTLAQLYRIRTTLLLNSTLTASEV", "length": 1088, "header": "tr|A0A8V0ZFV3-1|A0A8V0ZFV3_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G5 OS=Gallus gallus OX=9031 GN=PLEKHG5 PE=4 SV=1 CANONICAL=A0A8V0Z9W1-1" }, "locus": { "chromosome": "21", "start_pos": 589741, "end_pos": 579575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046040.1", "url": "https://www.ensembl.org/id/ENSGALT00010046040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027437.1", "url": "https://www.ensembl.org/id/ENSGALP00010027437.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 550, "start_aa": "Thr", "end_pos": 550, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr550", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426013", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" }, { "name": "endothelial cell migration", "id": "GO:0043542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043542", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1080, "end_pos": 1082, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W1" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 422, "end_pos": 614, "start_aa": "His", 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8G4-1", "uniprot_ac": "A0A8V0Z8G4", "uniprot_id": "A0A8V0Z8G4_CHICK", "mass": { "chemical_mass": 58295.0, "monoisotopic_mass": 58295.0 }, "refseq": { "ac": "XP_040529326", "name": "tubby protein homolog isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529326" }, "gene_names": [ { "name": "TUB", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ] }, { "name": "TUB", "type": "synonym", "evidence": [ { "id": "XP_040529326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529326" } ] } ], "protein_names": [ { "name": "Tubby-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#names_and_taxonomy" } ] }, { "name": "tubby protein homolog isoform X8", "type": "synonym", "evidence": [ { "id": "XP_040529326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040529326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4", "locus": { "chromosome": "5", "start_pos": 9862065, "end_pos": 9991580, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020692", "url": "https://www.ensembl.org/id/ENSGALG00010020692" } ] } } ], "crossref": [ { "id": "A0A8V0Z8G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423061", "url": "https://www.ncbi.nlm.nih.gov/gene/423061", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8G4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE91", "url": "https://www.orthodb.org/?gene=A0A8V0ZE91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLP2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16517:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16517:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16322", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16322", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040529326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040529326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAMDGERLCSASVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHVQEAEQEDVKVVVDAQAPKSTKKAKAASASCQTGSARKEKKGKHKGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLACE", "length": 524, "header": "tr|A0A8V0Z8G4-1|A0A8V0Z8G4_CHICK Isoform 1 of Tubby-like protein OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#A0A8V0Z8G4-1", "sequence": { "sequence": "MKAMDGERLCSASVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHVQEAEQEDVKVVVDAQAPKSTKKAKAASASCQTGSARKEKKGKHKGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLACE", "length": 524, "header": "tr|A0A8V0Z8G4-1|A0A8V0Z8G4_CHICK Isoform 1 of Tubby-like protein OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "locus": { "chromosome": "5", "start_pos": 9974155, "end_pos": 9871724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050012.1", "url": "https://www.ensembl.org/id/ENSGALT00010050012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029543.1", "url": "https://www.ensembl.org/id/ENSGALP00010029543.1" } ] } }, { "isoform_ac": "A0A8V0ZE91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#A0A8V0ZE91-1", "sequence": { "sequence": "MTSRHQADWIPYSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLA", "length": 477, "header": "tr|A0A8V0ZE91-1|A0A8V0ZE91_CHICK Computationally mapped isoform of TUB bipartite transcription factor OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "locus": { "chromosome": "5", "start_pos": 9928446, "end_pos": 9871729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049999.1", "url": "https://www.ensembl.org/id/ENSGALT00010049999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029535.1", "url": "https://www.ensembl.org/id/ENSGALP00010029535.1" } ] } }, { "isoform_ac": "A0A8V0ZFM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#A0A8V0ZFM3-1", "sequence": { "sequence": "MDGVGSSRTMSYSRWSYNSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLA", "length": 483, "header": "tr|A0A8V0ZFM3-1|A0A8V0ZFM3_CHICK Computationally mapped isoform of TUB bipartite transcription factor OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "locus": { "chromosome": "5", "start_pos": 9991566, "end_pos": 9871729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050015.1", "url": "https://www.ensembl.org/id/ENSGALT00010050015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029546.1", "url": "https://www.ensembl.org/id/ENSGALP00010029546.1" } ] } }, { "isoform_ac": "A0A8V0ZLN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#A0A8V0ZLN7-1", "sequence": { "sequence": "MRALKSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLACE", "length": 472, "header": "tr|A0A8V0ZLN7-1|A0A8V0ZLN7_CHICK Computationally mapped isoform of Tubby-like protein OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "locus": { "chromosome": "5", "start_pos": 9927771, "end_pos": 9871724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049996.1", "url": "https://www.ensembl.org/id/ENSGALT00010049996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029534.1", "url": "https://www.ensembl.org/id/ENSGALP00010029534.1" } ] } }, { "isoform_ac": "A0A8V0ZLP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4/entry#A0A8V0ZLP2-1", "sequence": { "sequence": "MTSRHQADWIPYSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNVDSRTRARRTKHSEEQAPLVESYLNSNSSTIYHVQEAEQEDVKVVVDAQAPKSTKKAKAASASCQTGSARKEKKGKHKGIDGPAAFQDDVQKAGSQVQILTVGQSSHDEDDGEKMASGQQQQSKQDLKTAMQKKDPHANTSWSSSTSQSSLVALDHVPGISSSMNFDEEEDEEDADSSSSSQLNSNTRPGSATSKKSSKEVASAPSPSTNEPLIDVDDLEEFAVRPAPQGATVKCRITRDKKGMDRGMYPTYYLHLEREHGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDNGVNPMKTTSSLEASVLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRNEHETLLARWQNKNTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLA", "length": 522, "header": "tr|A0A8V0ZLP2-1|A0A8V0ZLP2_CHICK Computationally mapped isoform of TUB bipartite transcription factor OS=Gallus gallus OX=9031 GN=TUB PE=3 SV=1 CANONICAL=A0A8V0Z8G4-1" }, "locus": { "chromosome": "5", "start_pos": 9928446, "end_pos": 9871729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050005.1", "url": "https://www.ensembl.org/id/ENSGALT00010050005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029539.1", "url": "https://www.ensembl.org/id/ENSGALP00010029539.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "intraciliary transport particle A binding", "id": "GO:0120160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8G4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" }, { "id": "PF01167", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01167" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubby C-terminal", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 519, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G4" }, { "id": "PF16322", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubby N-terminal", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 188, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8I1-1", "uniprot_ac": "A0A8V0Z8I1", "uniprot_id": "A0A8V0Z8I1_CHICK", "mass": { "chemical_mass": 22354.0, "monoisotopic_mass": 22354.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z8I1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z8I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RSGQPAIQPVPAGLKQETAGDLTGCRQGKCSSSAEKGPASRPQEGQMLVPAQRPAQPPFRRAYHRDRVHSESSARHQPTALNSHLRTWVLALPVPPWAACHAPHKQLIWKISEPIKILPVASHQTCSGVNRPTAAQACGGADPTSPAPGLAGCHLRTHGTEGSVGTGQGTPRALQVHDAGRRASSGSAGSAPQRAPSPRLPNTKPPNVGCRER", "length": 213, "header": "tr|A0A8V0Z8I1-1|A0A8V0Z8I1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z8I1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I1/entry#A0A8V0Z8I1-1", "sequence": { "sequence": "RSGQPAIQPVPAGLKQETAGDLTGCRQGKCSSSAEKGPASRPQEGQMLVPAQRPAQPPFRRAYHRDRVHSESSARHQPTALNSHLRTWVLALPVPPWAACHAPHKQLIWKISEPIKILPVASHQTCSGVNRPTAAQACGGADPTSPAPGLAGCHLRTHGTEGSVGTGQGTPRALQVHDAGRRASSGSAGSAPQRAPSPRLPNTKPPNVGCRER", "length": 213, "header": "tr|A0A8V0Z8I1-1|A0A8V0Z8I1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z8I1-1" }, "locus": { "chromosome": "6", "start_pos": 24069723, "end_pos": 24067742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045058.1", "url": "https://www.ensembl.org/id/ENSGALT00010045058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026921.1", "url": "https://www.ensembl.org/id/ENSGALP00010026921.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8K8-1", "uniprot_ac": "A0A8V0Z8K8", "uniprot_id": "A0A8V0Z8K8_CHICK", "mass": { "chemical_mass": 97112.0, "monoisotopic_mass": 97112.0 }, "refseq": { "ac": "NP_001026690", "name": "ESF1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026690" }, "gene_names": [ { "name": "ESF1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" } ] }, { "name": "ESF1", "type": "synonym", "evidence": [ { "id": "NP_001026690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026690" } ] } ], "protein_names": [ { "name": "ESF1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001026690", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026690" } ] }, { "name": "ESF1 nucleolar pre-rRNA processing protein homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720234.1, SRR13267658.9206.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000060.1. On Sep 23, 2021 this sequence version replaced NP_001026690.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026690" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ESF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8", "locus": { "chromosome": "3", "start_pos": 4700976, "end_pos": 4719356, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018644", "url": "https://www.ensembl.org/id/ENSGALG00010018644" } ] } } ], "crossref": [ { "id": "A0A8V0Z8K8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "428551", "url": "https://www.ncbi.nlm.nih.gov/gene/428551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428551", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHDFAID", "url": "https://omabrowser.org/oma/group/DHDFAID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8K8", "url": "https://www.orthodb.org/?gene=A0A8V0Z8K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12202:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12202:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026690", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASQKEILSDGRFSRVARDPRFWEMPEKDRKVKIDKRFRAMFHDKRFKMKCTVDKRGRPVNYTSVENLRKFYALSESDSELSEDGSEVRAERKKKKKKAKPKEEGDSVKPLPREEGKMKKQGVDQACEAVTKLDDLQNEGQKVASRFKLKEDSKKSRIEMDDSQKNEDLLCDREKEEGGESKGRSVSVQNKQKTSKPSGANTVKAPKRDCSIRGKTQESVTACRDSGAESDISESQVEEKKSLRESSEYTQSEEEELEDDGETGNDEESEDSEETDEEGGDSEEDEESDIEPDLARGIGNIETSSEDDDDLDDLFPREPEIEHSWGELDKDAPRGDEITSRLAVCNMDWDRLKAKDLLALFNSFIPKGGTIFSVKIYPSEFGKERLKEEEQQGPRELFDLPENTTEKDELYKEKLREYQFKRLKYFYAVVECDSPETANKIYEECDGLEFESSCSFIDLRFIPDNVTFDDKPKDAASEVNVSVYKPKYFTSAAMGTSKVDITWDETDHERVMSLNRTFNKEELLDMDFQAYLASSSEEEEEQQPGEGVAQEMEDDKPRKSQKDDEEQIAKYRELLQSIQEKEKKQEEKDIEMEIKWVPGLKETAEEMVKNRLEGKDNLTPWQKYLEKKKEKRNLKKKRKATAEREMSEDEIPSDVNLNDPYFAEELGKTGLKKKAEVVESNSEDEAEVERQKAEMALLMMDDEDDGRKHFNYKQIVEQQNLSKKKKKLLMKKKELLEDDFQVNVADTRFQAMFTSPLFNVDPSDPNFKKTKAVERILEEKARRREQKQQDLHEASKEQENKMAKKETKKSIDPALSMLVKSVKNKTEQFQARKKQKVK", "length": 838, "header": "tr|A0A8V0Z8K8-1|A0A8V0Z8K8_CHICK Isoform 1 of ESF1 nucleolar pre-rRNA processing protein homolog OS=Gallus gallus OX=9031 GN=ESF1 PE=1 SV=1 CANONICAL=A0A8V0Z8K8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8/entry#A0A8V0Z8K8-1", "sequence": { "sequence": "MASQKEILSDGRFSRVARDPRFWEMPEKDRKVKIDKRFRAMFHDKRFKMKCTVDKRGRPVNYTSVENLRKFYALSESDSELSEDGSEVRAERKKKKKKAKPKEEGDSVKPLPREEGKMKKQGVDQACEAVTKLDDLQNEGQKVASRFKLKEDSKKSRIEMDDSQKNEDLLCDREKEEGGESKGRSVSVQNKQKTSKPSGANTVKAPKRDCSIRGKTQESVTACRDSGAESDISESQVEEKKSLRESSEYTQSEEEELEDDGETGNDEESEDSEETDEEGGDSEEDEESDIEPDLARGIGNIETSSEDDDDLDDLFPREPEIEHSWGELDKDAPRGDEITSRLAVCNMDWDRLKAKDLLALFNSFIPKGGTIFSVKIYPSEFGKERLKEEEQQGPRELFDLPENTTEKDELYKEKLREYQFKRLKYFYAVVECDSPETANKIYEECDGLEFESSCSFIDLRFIPDNVTFDDKPKDAASEVNVSVYKPKYFTSAAMGTSKVDITWDETDHERVMSLNRTFNKEELLDMDFQAYLASSSEEEEEQQPGEGVAQEMEDDKPRKSQKDDEEQIAKYRELLQSIQEKEKKQEEKDIEMEIKWVPGLKETAEEMVKNRLEGKDNLTPWQKYLEKKKEKRNLKKKRKATAEREMSEDEIPSDVNLNDPYFAEELGKTGLKKKAEVVESNSEDEAEVERQKAEMALLMMDDEDDGRKHFNYKQIVEQQNLSKKKKKLLMKKKELLEDDFQVNVADTRFQAMFTSPLFNVDPSDPNFKKTKAVERILEEKARRREQKQQDLHEASKEQENKMAKKETKKSIDPALSMLVKSVKNKTEQFQARKKQKVK", "length": 838, "header": "tr|A0A8V0Z8K8-1|A0A8V0Z8K8_CHICK Isoform 1 of ESF1 nucleolar pre-rRNA processing protein homolog OS=Gallus gallus OX=9031 GN=ESF1 PE=1 SV=1 CANONICAL=A0A8V0Z8K8-1" }, "locus": { "chromosome": "3", "start_pos": 4718695, "end_pos": 4701320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045108.1", "url": "https://www.ensembl.org/id/ENSGALT00010045108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026946.1", "url": "https://www.ensembl.org/id/ENSGALP00010026946.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TQ21-1", "protein_name": "ESF1 nucleolar pre-rRNA processing protein homolog", "gene_name": "ESF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDCSSPGSSVHGFLQYLISSGICPVTHLKMASKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPIKHSTTEDLKRFYDLSDSDSDLSDENNKTLSQKKMKKKKPQTINEVESKNLVEDKKKKNKKIHQKDSGNNDLDNSERIQKMKTSCKSKKIDLVSLEKDSKEFTQKSTKGEKNTVQQSTDSFPKEQLRMVASGTSEIVQSPKVKYSETRRRKMQSVVPFIMARDSDGHEDSTGGKRFDKDALEEDSESASETGSDEESEDEITGICRAAAADLHDEEDDDDDDDDEGIGNDEEDDSEDDDESDSGPDLARGKGNIETSSEDEDDMADLLPEESGFEHAWRELDKDAPRADEITCRLAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEHVQGPVELLSIPEDAPEKDWASREKLRDYQFKRLKYYYAVVDCDSPETAAKIYEDCDGLEFESSCSFVDLRFIPDDITFDDEPKDVASEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRRFKKEELLDMDFQAYLASSSEDEEEMEEAQGDDGVSVEEDGKTKKSQKDDEEQIAKYRQLLQVIQDKEKKSKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQKALAEEASEDDVPSDVDMNDPYFAEEAKKIGIKEKKKSTKSAKDDISPEEEAEIERQKAEMALLVMDEEEESKKHFNYNKIVEHQNLSKKKKKQLMKKKELLEDDFEVNVKDARFQAMYTSHLFNLDPSDPNFKKTKAMERILEEKARQREQKEQGLTQATSEKEGEVQKESHKRSIDPALSMLIKSVKNKTEQFQARKKQKVK", "length": 885 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B8JKQ1-1", "protein_name": "ESF1 homolog", "gene_name": "esf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSKNTASGDDRFSKVKKDPRFWEMPNKERKIKIDKRFQSMFHDERFKLKYTVDKRGRPVKHTSTEDLKRFYKLSDSEQSDDDDDDEDEEKTEEEQKEKRGFEADKEAEVEEDDDDYEEEEGESDESEQEEEQKIQRNKEAKKTKKGVRVYEEDEDVESGVEEDDDDDDDDDEEESDSGPDLARGKGNIETSSDEDEEDEGDEVEDLLQREKEEIEHDWGEMWKDAPRSDDTSRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVLSVTVYPSEFGKERIHAEQTQGPLELSSLPENPDADTDEQRIYREKVRDYQFKRLRYYYAVVECDSAETASKIYEECDGIEYETSCSMIDLRFIPDDVTFDDEPKDRATDVDYGSYKPKLFTSTATTTSKVELTWDETDHDRVSALCRKFNKDELLDMDFKAYLASSSEEDEDEEEEQTKAVKPVESLPEEKKASKGKKGSGQIDKYRELLKSIQDKDKKKEDDDNNMNMEITWVPGLKESTENLVKKKMMGKDRLTPWEEFLEKKKEKKKEKRKGKKEVVEAELQISDDELPPDVDLSDPFFTEELVSTASLKNKESKKNRKKEEERTPEEQEEMERRKAEMELLMDDDEDDKHKHFNYDKIVEHQNLSKKKRKKLLKSNTPLEEGDDFKVDVQDPRFQAMFTSHLYNLDPSDPAYKKTKATQSILEEKQRRREEKHSQEETRRSKHTQEEDKTHTPSASSSTMDPSLSLLIKSVKNKTQQFQARKKQKTK", "length": 757 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O46307-1", "protein_name": "Uncharacterized protein", "gene_name": "EG:8D8.4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKKKDKSGKLDKQTTKKEAPSSSQANMGKAAGANDSENGIWQDSRFQHLLTDPRFRGVPKVQRKVKIDKRFQGMFTDDKFKVKYTVDKYGRPVNKSNAEDLRKFYELDENESSSGEEPAKKESDLDSEAEAEQQERRAEERAIANLEKEESNDTLESDSSEVSQSLRQRLTNPEIDYARGEGRLYTDSSSDEDSDDEDEGPELQIDHVWGELDNDAEHTEESTRRLAVCNMDWDRIRAEDLMVMLSSFLPPGGSILSVKIYPSEFGKARMAEEEVHGPKELVERVEPEDDSDEELVRQQDSDAEEGEDYHMEKLRQYQLNRLRYYYAVVECDSIDTADKVYKECDGIEYESSATRVDLRFIPDDTSFEEDTPSDECFELPDASSYKPRQFTTTALQQAKVDLTWDETALDRRELGDKLSSGQVDKLTDKELRQIVAYSSEEEDSEAEESPAEEAAQKAVSEDPQKSKPKKTSKQERIATYKNLLADILEQEKKEKEQKYEMEMTWNVEPQHEEAQPEQQAQAELTPIEKVIQKRSEKNRQRKEQRRQRQIEARGGDAGEDSDESMVPDGIDLNDAYFAEEFANGDYAPPKTKQDKKKKKKKGKDDGEEDVEAKRQEKELELLLDDGDGRDEKQHFSLTKILKKEEQEASGSKRKRRQKLKKSKNQPQNAEKLDDDFQVNLNDNRFSAVYKSHEYNIDPTHSHYKPTKGMQQIIGEKLKRRKEQGEGGAANGDADGDEQVAPKRSKQQLEQNALVKSLKRKIQLQQQGQKL", "length": 771 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q06344-1", "protein_name": "Pre-rRNA-processing protein ESF1", "gene_name": "ESF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGENPKKEGVDARFAGIYSDPKFKNTKTKDHKIKLDSRFSKKDLEVQHKSKVDKYGRKIKNAQNNRELEDFDKYFEKEAENDEDSEVNAKTVVDRARGEVPDDYVSSSDEFTSSDSESSGESEVESEEENEVEIENAKPESGDISKNLAVVNLDWDHVKSEDLMITFSSFVPKGGKIERVAIYPSEFGKERMQREEVEGPPKELFQKKNKNKTSKKKKTDDSDSDMDIGIKDLYEEGDADKDVDSRALRQYQLDRLRYYYAIVYCSDTTTSKAIYDNCDGTEYESTANMFDLRYVPDGMTFDDDVRDECSILPKNYRPHQFSTDALQHSSVKLTWDETPADRVEVAKRAFTQKEIDDMDFKAYLASDSDESDGQVDEEAKNKLKSLVGDFGFNSKKETPNDEDEEVDMEITFTPALEGGNEKSSEDKEETTIEKIRRKEKERRKARKQKVKELKQQSEKDKKSKLKSVNKKHTNDEEEIEKNAKSKAELELLMDDDDDTETQGTINNKAHFNMNEILRSEKEKHKKGRYQKKERIVEDTFTPDLEDPRFKEVFEDHDFAIDPTQPEFKGTQAMSKILKERSKRVKNKKRKLGGSENNMTNNADDNEDIGNLVNKLKKKSKSSKKVKV", "length": 628 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3V1V3-1", "protein_name": "ESF1 homolog", "gene_name": "Esf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSKQEIMDDQRFRRVSKDPRFWEMPEKERKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSDLSDEESKILSQKKAKQKKKQTKKEAKSIEKPIEEKKKETKKTDQKDSINKHDLNNSERVQKMKNSQKPQKIDSEISPKKDNEEFLQNKKKKRGTTDLSVEALPKGKLRTKDSSTSEMVKSSTMSSSKAKREKQSVVPVIMAKDNDGKMPDEDALEEDSDSASELGSDEESEDEIISDGKTSADEDESEEEDEEEEEDSEEEEEEEEEDESDSGPDLARGKGNVETSSEDEDDLADLFPEEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWASREKLRDYQFKRLKYYYAVAECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVALEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKKDELLDMDFQAYLASSSEDEEEVEEAPEGEEGVNIGEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQKALAEEDSEDELPSDVDFNDPYFAEEVKKIGIKKKSMKSAKDSASSEEETDLEKQKAEMALLVMDEEEDSKKHFNYDKIVEHQNLSKKKKKQLMKKKELVEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHRERKEELLIQAVERAQQDTGKPTQKQPMDPALSMLIKSVKNKTEQFQARKKQRVK", "length": 845 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76MT4-1", "protein_name": "ESF1 homolog", "gene_name": "Esf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKQEIMDDQRFRRVSKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSDLSDEESKVLDEKRVKEKKKQTKKETKSKTPIEEKKKETKKTDQKDSINKNDLNNSERIQKMKNSHKSPKIDSEVSPKDSEESLQSRKKKRDTTDLSVEASPKGKLRTKDPSTSAMVKSSTVSGSKAKREKQAVIMAKDNAGRMLHEEAPEEDSDSASELGRDEESEGEITSDDRASADDDENEDEEEEEDGEEEEEEEEEEDESDDESDSGPDLARGKGNVETSSEDEDDLADLFPEEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKQRMKEEQIQGPVELLSIPEDAPEKDWASREKLRDYQFKRLKYYYAVVECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDAASEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKKDELLDMDFEAYLASSSEDEEEVEEAPEGEDGVSIEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQKALAEEASEDEIPSDVDLNDPYFAEEVKKIGIKKKSMKSAKDGATSEEETELEKQKAEMALLVMDEEEDSKKHFNYDKIVEHQNLSKKKKKQLMKKKELLEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHREQKEERLIQAVERAQQDTGKPAQKQPMDPALSMLIKSVKNKTEQFQARKKQRIK", "length": 842 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H501-1", "protein_name": "ESF1 homolog", "gene_name": "ESF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQKVK", "length": 851 }, "evidence": [ { "id": "A0A8V0Z8K8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" }, { "id": "PF25121", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25121" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ESF1 RRM", "eco_id": "ECO_0000259", "start_pos": 339, "end_pos": 476, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8K8" }, { "id": "PF08159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NUC153", "eco_id": "ECO_0000259", "start_pos": 746, "end_pos": 773, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 824, "end_pos": 826 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA41-1", "uniprot_ac": "A0A8V0ZA41", "uniprot_id": "A0A8V0ZA41_CHICK", "mass": { "chemical_mass": 201389.0, "monoisotopic_mass": 201389.0 }, "refseq": {}, "gene_names": [ { "name": "BRWD3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ] } ], "protein_names": [ { "name": "Bromodomain and WD repeat-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L0#function" }, { "database": "UniProtKB", "id": "ARBA00053491", "url": "https://www.uniprot.org/uniprotkb/ARBA00053491#function" }, { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRWD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41", "locus": { "chromosome": "4", "start_pos": 9418963, "end_pos": 9368768, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019059", "url": "https://www.ensembl.org/id/ENSGALG00010019059" } ] } } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8L0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA41", "url": "https://www.orthodb.org/?gene=A0A8V0ZA41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAAPTQLEAELYYLIARFLQSGPCKKSAQVLVEELEEHQLIPRRLDWQGKEHRRSFEDLVAVNAHIPPDYLLRICERLGPLLDKEIPQSVLGVQTLLGVGRQSLLRAAKDFRHTLWKGSAFAALHRGRPPELPVNYGKPPNVVNILSARQLTGCGRFSHLFPTSTYQQMKMHKRILGHLSSVYCIAFDRSGRRIFTGSDDCLVKIWATDDGRLLSTLRGHSAEISDMAVNYENTLLAAGSCDKIVRVWCLRTCAPVAVLQGHSASITSIQFSPARKGTTRYLTSTGADGTICFWQWHANTMKFKDRPVKFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYYLGSESPEKMAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARVWQYHQQEWKSVVLDMATKMTGNNVASGEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQLLHSLSGHDDEVFVLEAHPFDQRIVLSAGHDGNIFIWDIDKGTKIRNYFNMIEGQGHGAVFDCKFSPDGQHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTRFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGMIRELQREQDLRLINEGETLPNPPLNRSHSVNGALRSPALEIASPPNVGLRRSGQIEGVRQMHHNAPRSQMATERDLMAWSRRVVVNELPPGISKVQEECRAAKGEIEIGLYTVEKKRKPSHTLQRNDYQPGSGRSLRRNQRKRQHAYQTRSTIEHSQQGASQNSRAREESDSSSEEDETVGTSDASVDDPVATWQSDSSSSDSSSEYSDWTADAGINLQPPKRQTRQAARKICSSSEDENLKGTKGVEQKRRKLKQPRKKKPSGLLSMEGEPSEEWLAPQWILDTIPRRSPFVPQMGDEIIYFRQGHEAYVRAVRKAKIYSINMQKQPWNKMELREQEFVKTVGIKYEVGPPTLCCLKLAFLDPITGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQAEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAYPEEVGAGVPVTPDELTALLYKPQEGEWGAHSRDEECERVIRGIEQLLSLDISNPFAVPVDLSAYPMYCTVVAYPTDLTTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDIYNKVKAEDLSSTDEEEEVAEVDVDSDAPGTSSGKQRQVRRRIKRQPMKGSPDAWKEQCKQLLNLIYEREDSEPFRQPVDLFSYPDYRDIVDTPMDFSTVKETLEAGNYTSPLEFYKDIRLIFCNSKAYTPNKKSRIYSMTLRLSALFENHMKNIISEYKSAMQCQKRKRPRYRKRLRSSSSSPSTSRASSPKGKQKQMKIQPKTNQNTSLPLTRTSSSVSSHVSDTTEEPLGSAAGEEVEVQPSSSGSNAQNRSGNTIDPGKVKPIRSKLTPVKQDHSPDGPLTNGDGREPRTGVKRKLISTSEDEHLEEGEAEEEENKKRELKEKSGLSSSESGESGSSSSSESRSGSDSDSESTSRTDQDYIDGDHDYSKVVQSKKPKRKIKRKFTSGKRTWQSRGTGRRGRWGRGCGRGRRGGGRGGRRGRGGRGASRGATRAKRARITDDEFETLFGGQFSENVFGGRFSRPPRIRTRNEGRRTVLYNDDSDNDNFVHTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1783, "header": "tr|A0A8V0ZA41-1|A0A8V0ZA41_CHICK Isoform 1 of Bromodomain and WD repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=BRWD3 PE=4 SV=1 CANONICAL=A0A8V0ZA41-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41/entry#A0A8V0Z8L0-1", "sequence": { "sequence": "MTFKIHVQLSHMEVAVNAHIPPDYLLRICERLGPLLDKEIPQSVLGVQTLLGVGRQSLLRAAKDFRHTLWKGSAFAALHRGRPPELPVNYGKPPNVVNILSARQLTGCGRFSHLFPTSTYQQMKMHKRILGHLSSVYCIAFDRSGRRIFTGSDDCLVKIWATDDGRLLSTLRGHSAEISDMAVNYENTLLAAGSCDKIVRVWCLRTCAPVAVLQGHSASITSIQFSPARKGTTRYLTSTGADGTICFWQWHANTMKFKDRPVKFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYYLGSESPEKMAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARVWQYHQQEWKSVVLDMATKMTGNNVASGEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQLLHSLSGHDDEVFVLEAHPFDQRIVLSAGHDGNIFIWDIDKGTKIRNYFNMIEGQGHGAVFDCKFSPDGQHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTRFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGMIRELQREQDLRLINEGETLPNPPLNRSHSVNGALRSPALEIASPPNVGLRRSGQIEGVRQMHHNAPRSQMATERDLMAWSRRVVVNELPPGISKVQEECRAAKGEIEIGLYTVEKKRKPSHTLQRNDYQPGSGRSLRRNQRKRQHAYQTRSTIEHSQQGASQNSRAREESDSSSEEDETVGTSDASVDDPVATWQSDSSSSDSSSEYSDWTADAGINLQPPKRQTRQAARKICSSSEDENLKGTKGVEQKRRKLKQPRKKKPSGLLSMEGEPSEEWLAPQWILDTIPRRSPFVPQMGDEIIYFRQGHEAYVRAVRKAKIYSINMQKQPWNKMELREQEFVKTVGIKYEVGPPTLCCLKLAFLDPITGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQAEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAYPEEVGAGVPVTPDELTALLYKPQEGEWGAHSRDEECERVIRGIEQLLSLDISNPFAVPVDLSAYPMYCTVVAYPTDLTTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDIYNKVKAEDLSSTDEEEEVAEVDVDSDAPGTSSGKQRVRRRIKRQPMKGSPDAWKEQCKQLLNLIYEREDSEPFRQPVDLFSYPDYRDIVDTPMDFSTVKETLEAGNYTSPLEFYKDIRLIFCNSKAYTPNKKSRIYSMTLRLSALFENHMKNIISEYKSAMQCQKRKRPRYRKRLRSSSSSPSTSRASSPKGKQKQMKIQPKTNQNTSLPLTRTSSSVSSHVSDTTEEPLGSAAGEEVEVQPSSSGSNAQNRSGNTIDPGKVKPIRSKLTPVKQDHSPDGPLTNGDGREPRTGVKRKLISTSEDEHLEEGEAEEEENKKRELKEKSGLSSSESGESGSSSSSESRSGSDSDSESTSRTDQDYIDGDHDYSKVVQSKKPKRKIKRKFTSGKRTWQSRGTGRRGRWGRWGRWSRGGRGGRGGRGCGRGRRGGGRGGRRGRGGRGASRGATRAKRARITDDEFETLFGGQFSENVFGGRFSRPPRIRTRNEGRRTVLYNDDSDNDNFVHTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1748, "header": "tr|A0A8V0Z8L0-1|A0A8V0ZA41_CHICK Computationally mapped isoform of Bromodomain and WD repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=BRWD3 PE=4 SV=1 CANONICAL=A0A8V0ZA41-1" }, "locus": { "chromosome": "4", "start_pos": 9417959, "end_pos": 9374244, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046153.1", "url": "https://www.ensembl.org/id/ENSGALT00010046153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027505.1", "url": "https://www.ensembl.org/id/ENSGALP00010027505.1" } ] } }, { "isoform_ac": "A0A8V0ZA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41/entry#A0A8V0ZA41-1", "sequence": { "sequence": "MATAAAPTQLEAELYYLIARFLQSGPCKKSAQVLVEELEEHQLIPRRLDWQGKEHRRSFEDLVAVNAHIPPDYLLRICERLGPLLDKEIPQSVLGVQTLLGVGRQSLLRAAKDFRHTLWKGSAFAALHRGRPPELPVNYGKPPNVVNILSARQLTGCGRFSHLFPTSTYQQMKMHKRILGHLSSVYCIAFDRSGRRIFTGSDDCLVKIWATDDGRLLSTLRGHSAEISDMAVNYENTLLAAGSCDKIVRVWCLRTCAPVAVLQGHSASITSIQFSPARKGTTRYLTSTGADGTICFWQWHANTMKFKDRPVKFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYYLGSESPEKMAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARVWQYHQQEWKSVVLDMATKMTGNNVASGEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQLLHSLSGHDDEVFVLEAHPFDQRIVLSAGHDGNIFIWDIDKGTKIRNYFNMIEGQGHGAVFDCKFSPDGQHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTRFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGMIRELQREQDLRLINEGETLPNPPLNRSHSVNGALRSPALEIASPPNVGLRRSGQIEGVRQMHHNAPRSQMATERDLMAWSRRVVVNELPPGISKVQEECRAAKGEIEIGLYTVEKKRKPSHTLQRNDYQPGSGRSLRRNQRKRQHAYQTRSTIEHSQQGASQNSRAREESDSSSEEDETVGTSDASVDDPVATWQSDSSSSDSSSEYSDWTADAGINLQPPKRQTRQAARKICSSSEDENLKGTKGVEQKRRKLKQPRKKKPSGLLSMEGEPSEEWLAPQWILDTIPRRSPFVPQMGDEIIYFRQGHEAYVRAVRKAKIYSINMQKQPWNKMELREQEFVKTVGIKYEVGPPTLCCLKLAFLDPITGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQAEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAYPEEVGAGVPVTPDELTALLYKPQEGEWGAHSRDEECERVIRGIEQLLSLDISNPFAVPVDLSAYPMYCTVVAYPTDLTTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDIYNKVKAEDLSSTDEEEEVAEVDVDSDAPGTSSGKQRQVRRRIKRQPMKGSPDAWKEQCKQLLNLIYEREDSEPFRQPVDLFSYPDYRDIVDTPMDFSTVKETLEAGNYTSPLEFYKDIRLIFCNSKAYTPNKKSRIYSMTLRLSALFENHMKNIISEYKSAMQCQKRKRPRYRKRLRSSSSSPSTSRASSPKGKQKQMKIQPKTNQNTSLPLTRTSSSVSSHVSDTTEEPLGSAAGEEVEVQPSSSGSNAQNRSGNTIDPGKVKPIRSKLTPVKQDHSPDGPLTNGDGREPRTGVKRKLISTSEDEHLEEGEAEEEENKKRELKEKSGLSSSESGESGSSSSSESRSGSDSDSESTSRTDQDYIDGDHDYSKVVQSKKPKRKIKRKFTSGKRTWQSRGTGRRGRWGRGCGRGRRGGGRGGRRGRGGRGASRGATRAKRARITDDEFETLFGGQFSENVFGGRFSRPPRIRTRNEGRRTVLYNDDSDNDNFVHTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1783, "header": "tr|A0A8V0ZA41-1|A0A8V0ZA41_CHICK Isoform 1 of Bromodomain and WD repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=BRWD3 PE=4 SV=1 CANONICAL=A0A8V0ZA41-1" }, "locus": { "chromosome": "4", "start_pos": 9417959, "end_pos": 9368967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046163.1", "url": "https://www.ensembl.org/id/ENSGALT00010046163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027511.1", "url": "https://www.ensembl.org/id/ENSGALP00010027511.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1366, "end_pos": 1368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1466, "end_pos": 1468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1511, "end_pos": 1513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA41" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 1164, "end_pos": 1234, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1366, "end_pos": 1368 }, { "start_pos": 1466, "end_pos": 1468 }, { "start_pos": 1511, "end_pos": 1513 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 677, "end_pos": 679 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8M3-1", "uniprot_ac": "A0A8V0Z8M3", "uniprot_id": "A0A8V0Z8M3_CHICK", "mass": { "chemical_mass": 149148.0, "monoisotopic_mass": 149148.0 }, "refseq": {}, "gene_names": [ { "name": "RRP12", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ] } ], "protein_names": [ { "name": "Ribosomal RNA processing 12 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRP12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3", "locus": { "chromosome": "6", "start_pos": 23153039, "end_pos": 23143174, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020730", "url": "https://www.ensembl.org/id/ENSGALG00010020730" } ] } } ], "crossref": [ { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8M3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48287:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48287:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPRRAARPSGRDVAAPRCGRRCPHCKWRRAPEAEARRGGAARGAGASMARCGRLRAGTAAKLRRWRKGHSSDCNPETRRHRLAARSRFYSRPTEKSNLTVDAVKLHNELQSGSLRVEQPSGSSQLPMEEGDAGEAATERSSGTFLSGLSDCTNVTFSRVQRFWESNSAAHKEICAVLAAVTDVIRSQGGKETETEYFAALMTTLEAVDSPESVAAVAYLLNLVLKRVPSPVLIKKFSDASKAFMNIISSQACSGSTSALRWVLSCLATLLRKQDLAAWSYPVTLQVYHGLLSFCVHTKPKVRKAAQHGVCSVLRGSEFMFGDEAPEHHPAAPSSAKFCVQEIEKAGGTKEATTTLHVLALLRDLLPCFPAAVLKTCCETLLRVMTLSHVLVTACAMQAFHSLFSAQPRTSCLPAELNAQIITALYDYVPSANDLQPLLTWLTTMERAHVNLGRLQKDLCWAHLPRLFSATMNCFLSPHSQVVAAAAQTLETLLNECIAPHMDELGNVSASAPAPGSYLCKMFRSVEEGLTYRFHAAWDGVLQVLEVFFEVCGKQCHPIMRKCLQSLCDLRLSPHFPYTTEVDQAVGAAVGAMGPEVLLEAVPLQIDGKEETLDFPRSWLLPVLRDYVQGARLGFFTSYFLPLAATLKSRALEFAQAGKSLESKIYDTLQWQVWTLLPGFCTRPTDVVEAFKGLARTLGMAISERPDLRPTVCQALRTLIHHGCGTDAERAEVGRFAKNFLPILFNVYSQPEEDGGSSSQRRSVLDTVRAYLTITDPQLVCGFLQKASEKLTSPESSEFARLSILDLVVAMSPYANEQALGSLYRTIQPSLQSKDHSMQKKAYRVLEEVCAAPHAPCQAFVHSHLEELQAVLLDSLKSAASPAKRPRLKCLFHIMKQLSAEHEPFVTALVPEVILCTKEVSVGARKNAFMLLVEMGHAFIRFGPTPQEAMERFLLLVYAGLTGSVTMISCTVLALTRLFFEFRDHMELNVVEQLLQNICLLLGSRTRDVVKAALGFIKVVLLLVDTTLLAKHVQTMLEAVGSLSDDMRRHFRMKLRNLFTKFIRKFGFELVQGLLPAEFHKVLVNIRKAEARSRKQRALRQAAAEGEEEEAPAQPKGDSMEEILADSEEEEEEEEERRRGKVRKKQARQKGQAWLKEGEEDEPLNFLDPNVSQRVLATEPSLKKSRGVKHDFQVSEDGRLIIHDEEEEVDNDEAKGVEEEVADVLQEVGLRSKKSQKRRFREEPDDDEPETGTYSQYRAGGSGIHRPLDKKPAFGAEYRSKKGKGDVKKKGQLDPYAYIPLNRAKLNKRKQAKMQGQFKGLMKGAQRGAKAGRKNRLKDRRP", "length": 1343, "header": "tr|A0A8V0Z8M3-1|A0A8V0Z8M3_CHICK Isoform 1 of Ribosomal RNA processing 12 homolog OS=Gallus gallus OX=9031 GN=RRP12 PE=1 SV=1 CANONICAL=A0A8V0Z8M3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3/entry#A0A8V0Z8M3-1", "sequence": { "sequence": "MAGPRRAARPSGRDVAAPRCGRRCPHCKWRRAPEAEARRGGAARGAGASMARCGRLRAGTAAKLRRWRKGHSSDCNPETRRHRLAARSRFYSRPTEKSNLTVDAVKLHNELQSGSLRVEQPSGSSQLPMEEGDAGEAATERSSGTFLSGLSDCTNVTFSRVQRFWESNSAAHKEICAVLAAVTDVIRSQGGKETETEYFAALMTTLEAVDSPESVAAVAYLLNLVLKRVPSPVLIKKFSDASKAFMNIISSQACSGSTSALRWVLSCLATLLRKQDLAAWSYPVTLQVYHGLLSFCVHTKPKVRKAAQHGVCSVLRGSEFMFGDEAPEHHPAAPSSAKFCVQEIEKAGGTKEATTTLHVLALLRDLLPCFPAAVLKTCCETLLRVMTLSHVLVTACAMQAFHSLFSAQPRTSCLPAELNAQIITALYDYVPSANDLQPLLTWLTTMERAHVNLGRLQKDLCWAHLPRLFSATMNCFLSPHSQVVAAAAQTLETLLNECIAPHMDELGNVSASAPAPGSYLCKMFRSVEEGLTYRFHAAWDGVLQVLEVFFEVCGKQCHPIMRKCLQSLCDLRLSPHFPYTTEVDQAVGAAVGAMGPEVLLEAVPLQIDGKEETLDFPRSWLLPVLRDYVQGARLGFFTSYFLPLAATLKSRALEFAQAGKSLESKIYDTLQWQVWTLLPGFCTRPTDVVEAFKGLARTLGMAISERPDLRPTVCQALRTLIHHGCGTDAERAEVGRFAKNFLPILFNVYSQPEEDGGSSSQRRSVLDTVRAYLTITDPQLVCGFLQKASEKLTSPESSEFARLSILDLVVAMSPYANEQALGSLYRTIQPSLQSKDHSMQKKAYRVLEEVCAAPHAPCQAFVHSHLEELQAVLLDSLKSAASPAKRPRLKCLFHIMKQLSAEHEPFVTALVPEVILCTKEVSVGARKNAFMLLVEMGHAFIRFGPTPQEAMERFLLLVYAGLTGSVTMISCTVLALTRLFFEFRDHMELNVVEQLLQNICLLLGSRTRDVVKAALGFIKVVLLLVDTTLLAKHVQTMLEAVGSLSDDMRRHFRMKLRNLFTKFIRKFGFELVQGLLPAEFHKVLVNIRKAEARSRKQRALRQAAAEGEEEEAPAQPKGDSMEEILADSEEEEEEEEERRRGKVRKKQARQKGQAWLKEGEEDEPLNFLDPNVSQRVLATEPSLKKSRGVKHDFQVSEDGRLIIHDEEEEVDNDEAKGVEEEVADVLQEVGLRSKKSQKRRFREEPDDDEPETGTYSQYRAGGSGIHRPLDKKPAFGAEYRSKKGKGDVKKKGQLDPYAYIPLNRAKLNKRKQAKMQGQFKGLMKGAQRGAKAGRKNRLKDRRP", "length": 1343, "header": "tr|A0A8V0Z8M3-1|A0A8V0Z8M3_CHICK Isoform 1 of Ribosomal RNA processing 12 homolog OS=Gallus gallus OX=9031 GN=RRP12 PE=1 SV=1 CANONICAL=A0A8V0Z8M3-1" }, "locus": { "chromosome": "6", "start_pos": 23152241, "end_pos": 23143373, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050103.1", "url": "https://www.ensembl.org/id/ENSGALT00010050103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029605.1", "url": "https://www.ensembl.org/id/ENSGALP00010029605.1" } ] } }, { "isoform_ac": "A0A8V0ZFI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3/entry#A0A8V0ZFI9-1", "sequence": { "sequence": "MARCGRLRAGTAAKLRRWRKGHSSDCNPETRRHRLAARSRFYSRPTEKSNLTVDAVKLHNELQSGSLRVEQPSGSSQLPMEEGDAGEAATERSSGTFLSGLSDCTNVTFSRVQRFWESNSAAHKEICAVLAAVTDVIRSQGGKETETEYFAALMTTLEAVDSPESVAAVAYLLNLVLKRVPSPVLIKKFSDASKAFMNIISSQACSGSTSALRWVLSCLATLLRKQDLAAWSYPVTLQVYHGLLSFCVHTKPKVRKAAQHGVCSVLRGSEFMFGDEAPEHHPAAPSSAKFCVQEIEKAGGTKEATTTLHVLALLRDLLPCFPAAVLKTCCETLLRVMTLSHVLVTACAMQAFHSLFSAQPRTSCLPAELNAQIITALYDYVPSANDLQPLLTWLTTMERAHVNLGRLQKDLCWAHLPRLFSATMNCFLSPHSQVVAAAAQTLETLLNECIAPHMDELGNVSASAPAPGSYLCKMFRSVEEGLTYRFHAAWDGVLQVLEVFFEVCGKQCHPIMRKCLQSLCDLRLSPHFPYTTEVDQAVGAAVGAMGPEVLLEAVPLQIDGKEETLDFPRSWLLPVLRDYVQGARLGFFTSYFLPLAATLKSRALEFAQAGKSLESKIYDTLQWQVWTLLPGFCTRPTDVVEALRTLIHHGCGTDAERAEVGRFAKNFLPILFNVYSQPEEDGGSSSQRRSVLDTVRAYLTITDPQLVCGFLQKASEKLTSPESSEFARLSILDLVVAMSPYANEQALGSLYRTIQPSLQSKDHSMQKKAYRVLEEVCAAPHAPCQAFVHSHLEELQAVLLDSLKSAASPAKRPRLKCLFHIMKQLSAEHEPFVTALVPEVILCTKEVSVGARKNAFMLLVEMGHAFIRFGPTPQEAMERFLLLVYAGLTGSVTMISCTVLALTRLFFEFRDHMELNVVEQLLQNICLLLGSRTRDVVKAALGFIKVVLLLVDTTLLAKHVQTMLEAVGSLSDDMRRHFRMKLRNLFTKFIRKFGFELVQGLLPAEFHKVLVNIRKAEARSRKQRALRQAAAEGEEEEAPAQPKGDSMEEILADSEEEEEEEEERRRGKVRKKQARQKGQAWLKEGEEDEPLNFLDPNVSQRVLATEPSLKKSRGVKHDFQVSEDGRLIIHDEEEEVDNDEAKGVEEEVADVLQEVGLRSKKSQKRRFREEPDDDEPETGTYSQYRAGGSGIHRPLDKKPAFGAEYRSKKGKGDVKKKGQLDPYAYIPLNRAKLNKRKQAKMQGQFKGLMKGAQRGAKAGRKNRLKDRRP", "length": 1269, "header": "tr|A0A8V0ZFI9-1|A0A8V0ZFI9_CHICK Computationally mapped isoform of Ribosomal RNA processing 12 homolog OS=Gallus gallus OX=9031 GN=RRP12 PE=1 SV=1 CANONICAL=A0A8V0Z8M3-1" }, "locus": { "chromosome": "6", "start_pos": 23152241, "end_pos": 23143520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050102.1", "url": "https://www.ensembl.org/id/ENSGALT00010050102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029604.1", "url": "https://www.ensembl.org/id/ENSGALP00010029604.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 946, "start_aa": "Thr", "end_pos": 946, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr946", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1171, "end_pos": 1173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" }, { "id": "PF08161", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08161" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRP12 HEAT", "eco_id": "ECO_0000259", "start_pos": 478, "end_pos": 751, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z8M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8M3" }, { "id": "PF25772", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25772" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRP12 N-terminal HEAT", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 407, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 946 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1171, "end_pos": 1173 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9L1-1", "uniprot_ac": "A0A8V0Z9L1", "uniprot_id": "A0A8V0Z9L1_CHICK", "mass": { "chemical_mass": 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{ "uniprot_canonical_ac": "A0A8V0Z8N6-1", "uniprot_ac": "A0A8V0Z8N6", "uniprot_id": "A0A8V0Z8N6_CHICK", "mass": { "chemical_mass": 28175.0, "monoisotopic_mass": 28175.0 }, "refseq": { "ac": "XP_046759356", "name": "stanniocalcin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759356" }, "gene_names": [ { "name": "STC1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N6" } ] }, { "name": "STC1", "type": "synonym", "evidence": [ { "id": "XP_046759356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759356" } ] } ], "protein_names": [ { "name": "Stanniocalcin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N6/entry#names_and_taxonomy" } ] }, { "name": "stanniocalcin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046759356", "database": "RefSeq", 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This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759356" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N6", "locus": { "chromosome": "22", "start_pos": 1207038, "end_pos": 1197275, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019097", "url": "https://www.ensembl.org/id/ENSGALG00010019097" } ] } } ], "crossref": [ { "id": "A0A8V0Z8N6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8N6", "database": 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"url": "https://www.orthodb.org/?gene=F1NGZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGZ1", "url": "https://www.uniprot.org/uniprotkb/F1NGZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NGZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNQASMQDDQSRHCKFLSYMFYQAVRDHKPVWMLEDMRTMEYFYWEENASLRTYSPSEALLYAVVHNHLPYAQYLLSHFPEEALKVPGEHFCYCPSSAPHLAMAVTYDRRDILGLIIKIAHKLPSLNSYINRTGCFHLEDGKTPLHLACELLRSETVLILLGNGASPRIEDSKGLTPLDVILEQMWDSKVNMATKKLCLDYLLLFMPNPQFKMRKVLQDHPEHWTALLGEEKFNSLVGNTPASLYLQAMQTILQTLPPSHFPKSIQELPIPQALKPLPSYGKKQSTKNVACSI", "length": 295, "header": "tr|A0A8V0Z8N7-1|A0A8V0Z8N7_CHICK Isoform 1 of Ankyrin repeat domain-containing protein 9 OS=Gallus gallus OX=9031 GN=ANKRD9L PE=4 SV=1 CANONICAL=A0A8V0Z8N7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N7/entry#A0A8V0Z8N7-1", "sequence": { "sequence": "MASNQASMQDDQSRHCKFLSYMFYQAVRDHKPVWMLEDMRTMEYFYWEENASLRTYSPSEALLYAVVHNHLPYAQYLLSHFPEEALKVPGEHFCYCPSSAPHLAMAVTYDRRDILGLIIKIAHKLPSLNSYINRTGCFHLEDGKTPLHLACELLRSETVLILLGNGASPRIEDSKGLTPLDVILEQMWDSKVNMATKKLCLDYLLLFMPNPQFKMRKVLQDHPEHWTALLGEEKFNSLVGNTPASLYLQAMQTILQTLPPSHFPKSIQELPIPQALKPLPSYGKKQSTKNVACSI", "length": 295, "header": "tr|A0A8V0Z8N7-1|A0A8V0Z8N7_CHICK Isoform 1 of Ankyrin repeat domain-containing protein 9 OS=Gallus gallus OX=9031 GN=ANKRD9L PE=4 SV=1 CANONICAL=A0A8V0Z8N7-1" }, "locus": { "chromosome": "3", "start_pos": 8351099, "end_pos": 8345511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042313.1", "url": "https://www.ensembl.org/id/ENSGALT00010042313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024803.1", "url": "https://www.ensembl.org/id/ENSGALP00010024803.1" } ] } }, { "isoform_ac": "F1NGZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8N7/entry#F1NGZ1-1", "sequence": { "sequence": "MASNQASMQDDQSRHCKFLSYMFYQAVRDHKPVWMLEDMRTMEYFYWEENASLRTYSPSEALLYAVVHNHLPYAQYLLSHFPEEALKVPGEHFCYCPSSAPHLAMAVTYDRRDILGLIIKIAHKLPSLNSYINRTGCFHLEDGKTPLHLACELLRSETVLILLGNGASPRIEDSKGLTPLDVILEQMWDSKVNMATKKLCLDYLLLFMPNPQFKMRKVLQDHPEHWTALLGEEKFNSLVGNTPASLYLQAMQTILQTLPPSHFPKSIQELPIPQALKPLPSYGKKQSTKNVHH", "length": 293, "header": "tr|F1NGZ1-1|A0A8V0Z8N7_CHICK Computationally mapped isoform of Ankyrin repeat domain-containing protein 9 OS=Gallus gallus OX=9031 GN=ANKRD9L PE=4 SV=5 CANONICAL=A0A8V0Z8N7-1" }, "locus": { "chromosome": "3", "start_pos": 8350342, "end_pos": 8345511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042312.1", "url": "https://www.ensembl.org/id/ENSGALT00010042312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024802.1", "url": "https://www.ensembl.org/id/ENSGALP00010024802.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421298", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RCM1-1", "protein_name": "Uncharacterized protein LOC550384", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDERKQHKFISFLFYQAVRDLKPVWMLEDMRTMETFYWEEDAKQRTYSPSEALLYAIVHDHRPYAHYLLSRFSDEALEMPGESFYCCPSSAPHLAMAVRYDRRDILAHILQVAHQLPGLRSYMNRGGCFHLEDGKTPLHLACELLRADAVMLLLGNGASPQAEDHNGMTPLDVVLQQLRDSKANVGAKKSCLENLLMFMPEMRFKMKSALQKERQCWSKVLGEDKLNYLTGREPAPLFLIAMRRILAQLPPEQFPSSLDKLPIPAALKPRAHRGRLSVA", "length": 280 }, "evidence": [ { "id": "A0A8V0Z8N7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8N7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8P7-1", "uniprot_ac": "A0A8V0Z8P7", "uniprot_id": "A0A8V0Z8P7_CHICK", "mass": { "chemical_mass": 37867.0, "monoisotopic_mass": 37867.0 }, "refseq": { "ac": "XP_414708", "name": "UPF0764 protein C16orf89 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414708" }, "gene_names": [ { "name": "C16orf89", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7" } ] }, { "name": "C16orf89", "type": "synonym", "evidence": [ { "id": "XP_414708", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414708" } ] } ], "protein_names": [ { "name": "Chromosome 16 open reading frame 89", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7/entry#names_and_taxonomy" } ] }, { "name": "UPF0764 protein C16orf89 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_414708", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414708" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414708.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414708" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C16orf89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7", "locus": { "chromosome": "14", "start_pos": 13384535, "end_pos": 13391041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018690", "url": "https://www.ensembl.org/id/ENSGALG00010018690" } ] } } ], "crossref": [ { "id": "A0A8V0Z8P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "416394", "url": "https://www.ncbi.nlm.nih.gov/gene/416394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MTRPGCS", "url": "https://omabrowser.org/oma/group/MTRPGCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8P7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33539:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33539:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414708", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYLPFLLLVTACEASCLKTEPDVRSSIIPVLEKVTVFMENRYQDINLDAVLGFRVLQGYLKGALEKWPLEHELLAQRAQVESMIKKLSSLLEKATHSLVQNDPEYFKEFAPILGPHFWIFPHSWNQTDPLMAYSSFGSTNCFTEKMRDACFTYLLGTWKENGKSCIVTSACRNTMTKPACSNYCLSHQLLYFIFADVKGCSDHLFLKTQDYKNMFCASMMKINLEIEHNGFNISSRDLFMENIMLCGMSGFSDFYKLRWLEKILTWQMPKEGCFGEPSKELEHSSAVEDQKQLLRRVKRREKMFADGCSSHHTAVAAGSLGGFLYYHCS", "length": 330, "header": "tr|A0A8V0Z8P7-1|A0A8V0Z8P7_CHICK Isoform 1 of Chromosome 16 open reading frame 89 OS=Gallus gallus OX=9031 GN=C16orf89 PE=4 SV=1 CANONICAL=A0A8V0Z8P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8P7/entry#A0A8V0Z8P7-1", "sequence": { "sequence": "MLYLPFLLLVTACEASCLKTEPDVRSSIIPVLEKVTVFMENRYQDINLDAVLGFRVLQGYLKGALEKWPLEHELLAQRAQVESMIKKLSSLLEKATHSLVQNDPEYFKEFAPILGPHFWIFPHSWNQTDPLMAYSSFGSTNCFTEKMRDACFTYLLGTWKENGKSCIVTSACRNTMTKPACSNYCLSHQLLYFIFADVKGCSDHLFLKTQDYKNMFCASMMKINLEIEHNGFNISSRDLFMENIMLCGMSGFSDFYKLRWLEKILTWQMPKEGCFGEPSKELEHSSAVEDQKQLLRRVKRREKMFADGCSSHHTAVAAGSLGGFLYYHCS", "length": 330, "header": "tr|A0A8V0Z8P7-1|A0A8V0Z8P7_CHICK Isoform 1 of Chromosome 16 open reading frame 89 OS=Gallus gallus OX=9031 GN=C16orf89 PE=4 SV=1 CANONICAL=A0A8V0Z8P7-1" }, "locus": { "chromosome": "14", "start_pos": 13391006, "end_pos": 13384720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045189.1", "url": "https://www.ensembl.org/id/ENSGALT00010045189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026986.1", "url": "https://www.ensembl.org/id/ENSGALP00010026986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZFA0-1", "protein_name": "Similar to human chromosome 16 open reading frame 89", "gene_name": "C10h16orf89", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARISLLLLLLLSLPQQLSSLPWPDTAQGTMAGLILTALEKATLFLEDRLPKINLDGAVGFQVLEVQLRGVQEKWAHNPLLQPLSLRAGQLANTLFALLQNSIFYLKQSDPTYLREFQPSLQPGFWKLPHAWTRTNASLVYPWLEPLDSFSEESSDACLVQLLGTGTDSRQPCRLSDFCRTLMTKAGCSGYSLSHQLLFFLWARMQGCTEGLFLQSQHYIDIFCANMMDLNRRAEAMGYAYPTQDLFMENIMFCGMAGFSDFYKLHWLEAILNWQNPQVGCFGKPDTKGEPPEVPHRQGVLRRVRRREKLFEDGCSCHNTATAVAALGGFLYILAEYHPDNGEPTPPTRSPASNYQDGAASPDAQRIGRPLSISS", "length": 375 }, "evidence": [ { "id": "A0A8V0Z8P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N2J8-1", "protein_name": "Chromosome 25 C16orf89 homolog", "gene_name": "C25H16orf89", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSPGLRLLLLLLAAPPLQPSWLPPPDTPEGKATITGFILSALDRATSFLKKRLPEINLDGVVGFRMLEVQLRGVQEKWALDSQLQPLSLRVGKLVEKLAPLLHDSIFYLNLSDPEYLRQFQLTIEPGFWKLPHAWTRTESSMVYPTFEQEDSFSEELSDLCLVQLLGTGTNSSQPCRLSNFCRSLMTRPGCSGYCLSHQLLFFLSARMRGCTKGLFRQSQRYMNVFCANMMDLNRRADAIGYAYPTRDIFMENIVFCGMSGFSDFYKLRWLQAILSWQKPQEGCFGEPAAEDEELPKAIQYQQHFLRRVKRREKQFADGCSSHNTAMAVAALGGFLYILAEYPPAEGKLRPPTMTPPNGH", "length": 361 }, "evidence": [ { "id": "A0A8V0Z8P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3L736-1", "protein_name": "Chromosome 3 C16orf89 homolog", "gene_name": "C16orf89", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSPGLLLLLLLLAPPPLQPSLLPPLDTPGGKAAVTGLILSALERATSFLEKRLPEINLDGMVGFRVLEAQLQGVQEKWARDPQLQPLSLRVGELADKLAPLLHRSIFYLRLSDPEYLREFQPTIEPGFWKLPRAWTHTSDSMVYTSFEPQDSFSEEHSDLCLAQLLGTGADSSPPCRLSDFCRNLMTKPGCSGYCLSHQMLFFLSARMRGCTEGLFRQSRRYMNLFCANMMDVNRRAEAIGYTYPTRDVFMENIMFCGLGGFSDFYKLRWLEAILSWQKPQEGCFGRPAADGEELPKAIHHQQHSLRRVKRREKQFTDGCSSHNTAMAVAALGGFLYILAEHPPADRELQPSVPALLSDH", "length": 361 }, "evidence": [ { "id": "A0A8V0Z8P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8P7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UST5-1", "protein_name": "UPF0764 protein C16orf89 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLGLLLLLLLALPPHFSSVSWPDTAQGTMANLILTALEKATLFLEDRLPTINLDGVVGFQVLEVQLRGVQEKWAHKPLLQPLSMRAGQMANTLSALLQKSIFYLKQSDPTYLREFQPSIQPGFWKLPNDWTRTNASLVYPWLEPLDSFSEESSDVCLVQLLGTGTDSSQPCRLSNFCRTLMTKAGCSGYSLSHQLLFFLWARMQGCTEGLFLQSQHYMDIFCANMMELNHRAEAVGYAYPTQDLFMENIMFCGMAGFSDFYKLRWLEAILSWQNPQVGCFGRPDTKGEPSEVPHQQGILRRVRRREKLFADGCSCHNTATAVAALGGFLYILAEYHPDNGDAHPEYYPNHGDPYSSSQSPASNYQDGAAGPDVQRTGRPLSVS", "length": 385 }, "evidence": [ { "id": "A0A8V0Z8P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z8P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UX73-1", "protein_name": "UPF0764 protein C16orf89", "gene_name": "C16orf89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Protein Classification" ] }, { "id": "IPR052118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46150:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46150:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25336", "url": 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"header": "tr|A0A8V0Z8Q3-1|A0A8V0Z8Q3_CHICK Isoform 1 of Synapse defective Rho GTPase homolog 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z8Q3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q3/entry#A0A8V0Z8Q3-1", "sequence": { "sequence": 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"header": "tr|A0A8V0Z8Q3-1|A0A8V0Z8Q3_CHICK Isoform 1 of Synapse defective Rho GTPase homolog 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z8Q3-1" }, "locus": { "chromosome": "8", "start_pos": 16062576, "end_pos": 16039174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050171.1", "url": "https://www.ensembl.org/id/ENSGALT00010050171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029645.1", "url": "https://www.ensembl.org/id/ENSGALP00010029645.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 119, "start_aa": "Thr", "end_pos": 119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr119", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q3", "url": 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{ "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8S8-1", "uniprot_ac": "A0A8V0Z8S8", "uniprot_id": "A0A8V0Z8S8_CHICK", "mass": { "chemical_mass": 111987.0, "monoisotopic_mass": 111987.0 }, "refseq": { "ac": "NP_001244275", "name": "ribosome-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" }, "gene_names": [ { "name": "RRBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8" } ] }, { "name": "RRBP1", "type": "synonym", "evidence": [ { "id": "NP_001244275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" } ] } ], "protein_names": [ { "name": "EDT-soluble/130 kDa protein", "type": "synonym", "evidence": [ { "id": "NP_001244275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" } ] }, { "name": "Ribosome binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8/entry#names_and_taxonomy" } ] }, { "name": "ribosome binding protein 1 homolog 180kDa (dog)", "type": "synonym", "evidence": [ { "id": "NP_001244275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" } ] }, { "name": "ribosome-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001244275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.321800.1, SRR13267661.24664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001244275.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001244275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8", "locus": { "chromosome": "3", "start_pos": 15239752, "end_pos": 15195409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018724", "url": "https://www.ensembl.org/id/ENSGALG00010018724" } ] } } ], "crossref": [ { "id": "A0A8V0Z8S8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8S8", "database": "AlphaFoldDB", "categories": [] }, { "id": "396414", "url": "https://www.ncbi.nlm.nih.gov/gene/396414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396414", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHKMQED", "url": "https://omabrowser.org/oma/group/IHKMQED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8S4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8S8", "url": "https://www.orthodb.org/?gene=A0A8V0Z8S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001244275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVYDPQTLGVVVFGGFMVISAIGIFLVSTFSMKETSYEEALAKQRKELEKTNQHKIEKKKKEKPVEKKGKAKKKEEKPNGKIPEQQVTQEVTDSSKDVVVEPAVVPEPIAVESPIAAVSVPPQEKEKPALSPKEKRKKEKKVAKVEPAPSPALASPPASVPKGSPVLEVTPKEVPVVAVPPVGTQQSAPVVSSVPIKKPEALPTHEEQKHDGPVKKKSASKKKAEPAPADSDGPLYLPYKTLVSTISSMAFSEGEAQQLIEILTERAGIVQDTWHTATQKGDPVAVLKRQLEEKEKQLTAEQEDAAAARNKLRELSKELAAEKAKAAASESKLKEQLVTREREITAVQARMQASYQDHVNETQQLQGKIRALQEQLENGPNTQLARLQQENSILRDALNQATSQTESKQNAELAKLRQECNKLMKELSEKSEVLQQEEQQKKSWEIKAAASEKQIEQLQTSQREMEATLQKRLDEVSDELRKTQTSYRSLVADAEKAKGQQQSIAELQAKLLSSETEVKSKLLELDSLKGKLQEASSENTRLLERIKSIEALLEAGRMREAEEDRDLQAANEAEMKQLQLRLQEKTDQLLSLEREAAELREAMEQQKTKNNDLREKNWKAVEALTTVEKACEEKLLAATKAKEELAHQLDVLQTRTKETLLSALPEVTVSQQDYEAWLQEFKEKAVNVLKQHTVMTEPVDSALKLKEAEEAQSTLQAECEQYRAILAETEGMLRDLQKSVEEEEQVWKAKLTVSEEELQKSQLQLKSLEDMIEKLKAELQSTDQLKEYISLLEAQLENHLQTASSERQNYTKEVEGLRQLLSESQEQLEAAKTETQKQSKELALVRQQLSEMKSHVQDGEVAGSQADLGDPTPFELKMQLEQNEALMEKEQELRQKLTRELEEAQSSACSLQAELEKLRLAENAAASDMEEAQHLKERLEKEKKLTRDLGQAATKLQELLKVTQDQLAKERETVKKLKEQLHEKGEEDSSKEGTSV", "length": 997, "header": "tr|A0A8V0Z8S8-1|A0A8V0Z8S8_CHICK Isoform 1 of Ribosome binding protein 1 OS=Gallus gallus OX=9031 GN=RRBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8S8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8/entry#A0A8V0Z8S4-1", "sequence": { "sequence": "MDVYDPQTLGVVVFGGFMVISAIGIFLVSTFSMKETSYEEALAKQRKELEKTNQHKIEKKKKEKPVEKKGKAKKKEEKPNGKIPEQQVTQEVTDSSKDVVVEPAVVPEPIAVESPIAAVSVPPQEKEKPALSPKEKRKKEKKVAKVEPAPSPALASPPASVPKGSPVLEVTPKEVPVVAVPPVGTQQSAPVVSSVPIKKPEALPTHEEQKHDGPVKKKSASKKKAEPAPADSDGPLYLPYKTLVSTISSMAFSEGEAQQLIEILTERAGIVQDTWHTATQKGDPVAVLKRQLEEKEKQLTAEQEDAAAARNKLRELSKELAAEKAKAAASESKLKEQLVTREREITAVQARMQASYQDHVNETQQLQGKIRALQEQLENGPNTQLARLQQENSILRDALNQATSQTESKQNAELAKLRQECNKLMKELSEKSEVLQQEEQQKKSWEIKAAASEKQIEQLQTSQREMEATLQKRLDEVSDELRKTQTSYRSLVADAEKAKGQQQSIAELQAKLLSSETEVKSKLLELDSLKGKLQEASSENTRLLERIKSIEALLEAGRMREAEEDRDLQAANEAEMKQLQLRLQEKTDQLLSLEREAAELREAMEQQKTKNNDLREKNWKAVEALTTVEKACEEKLLAATKAKEELAHQLDVLQTRTKETLLSALPEVTVSQQDYEAWLQEFKEKAVNVLKQHTVMTEPVDSALKLKEAEEAQSTLQAECEQYRAILAETEGMLRDLQKSVEEEEQVWKAKLTVSEEELQKSQLQLKSLEDMIEKLKAELQSTDQLKEYISLLEAQLENHLQTASSERQNYTKEVEGLRQLLSESQEQLEAAKTETQKQSKELALLKMQLEQNEALMEKEQELRQKLTRELEEAQSSACSLQAELEKLRLAENAAASDMEEAQHLKERLEKEKKLTRDLGQAATKLQELLKVTQDQLAKERETVKKLKEQLHEKGEEDSSKEGTSV", "length": 966, "header": "tr|A0A8V0Z8S4-1|A0A8V0Z8S8_CHICK Computationally mapped isoform of Ribosome binding protein 1 OS=Gallus gallus OX=9031 GN=RRBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8S8-1" }, "locus": { "chromosome": "3", "start_pos": 15239212, "end_pos": 15221450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045250.1", "url": "https://www.ensembl.org/id/ENSGALT00010045250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027016.1", "url": "https://www.ensembl.org/id/ENSGALP00010027016.1" } ] } }, { "isoform_ac": "A0A8V0Z8S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8/entry#A0A8V0Z8S8-1", "sequence": { "sequence": "MDVYDPQTLGVVVFGGFMVISAIGIFLVSTFSMKETSYEEALAKQRKELEKTNQHKIEKKKKEKPVEKKGKAKKKEEKPNGKIPEQQVTQEVTDSSKDVVVEPAVVPEPIAVESPIAAVSVPPQEKEKPALSPKEKRKKEKKVAKVEPAPSPALASPPASVPKGSPVLEVTPKEVPVVAVPPVGTQQSAPVVSSVPIKKPEALPTHEEQKHDGPVKKKSASKKKAEPAPADSDGPLYLPYKTLVSTISSMAFSEGEAQQLIEILTERAGIVQDTWHTATQKGDPVAVLKRQLEEKEKQLTAEQEDAAAARNKLRELSKELAAEKAKAAASESKLKEQLVTREREITAVQARMQASYQDHVNETQQLQGKIRALQEQLENGPNTQLARLQQENSILRDALNQATSQTESKQNAELAKLRQECNKLMKELSEKSEVLQQEEQQKKSWEIKAAASEKQIEQLQTSQREMEATLQKRLDEVSDELRKTQTSYRSLVADAEKAKGQQQSIAELQAKLLSSETEVKSKLLELDSLKGKLQEASSENTRLLERIKSIEALLEAGRMREAEEDRDLQAANEAEMKQLQLRLQEKTDQLLSLEREAAELREAMEQQKTKNNDLREKNWKAVEALTTVEKACEEKLLAATKAKEELAHQLDVLQTRTKETLLSALPEVTVSQQDYEAWLQEFKEKAVNVLKQHTVMTEPVDSALKLKEAEEAQSTLQAECEQYRAILAETEGMLRDLQKSVEEEEQVWKAKLTVSEEELQKSQLQLKSLEDMIEKLKAELQSTDQLKEYISLLEAQLENHLQTASSERQNYTKEVEGLRQLLSESQEQLEAAKTETQKQSKELALVRQQLSEMKSHVQDGEVAGSQADLGDPTPFELKMQLEQNEALMEKEQELRQKLTRELEEAQSSACSLQAELEKLRLAENAAASDMEEAQHLKERLEKEKKLTRDLGQAATKLQELLKVTQDQLAKERETVKKLKEQLHEKGEEDSSKEGTSV", "length": 997, "header": "tr|A0A8V0Z8S8-1|A0A8V0Z8S8_CHICK Isoform 1 of Ribosome binding protein 1 OS=Gallus gallus OX=9031 GN=RRBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8S8-1" }, "locus": { "chromosome": "3", "start_pos": 15239212, "end_pos": 15221450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045256.1", "url": "https://www.ensembl.org/id/ENSGALT00010045256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027021.1", "url": "https://www.ensembl.org/id/ENSGALP00010027021.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396414", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q1LXR3-1", "protein_name": "Ribosome-binding protein 1b", "gene_name": "rrbp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVYDPQTLGIVVFGGFMVFSAIGITLVSTFSMKETSYEEALAKQRQDSGKTQSQRSDKKKKASEKKTKSKKKEEKQNGNLPESEPEPEPIPEPVVENSEPKAVPQVEPEPQPVAVPEPVPEVKPKPVVSEPVPNIVECAAPPTVSAVVAPLAPSPKEKKKKKVAKVEPAPVKPVEVPIVVAKVEPVVAESVVKAVVSPEVAAVPEEPKVETPTKKKPKKKAEPAVSVEEVDIPQPSPYKTLVSSLNSALFSESETQKLFEIISKKAGRDSWQLASQKGDPLATLKKQLEEKEKQLTAEQGNVAAAKTRVRELTKELNTAKNKIASTEARMSSELSARGQEITALQARMQTSYQEHVNESQQLNSKIQSLQEQLENGPMAQLARLEQENSILRDALNQATSQAESRQNAELAKLRQDCVRLNRELKECTASQQFEEERRKSLETKLAAAEEQLKQTQASCVGTEQALQKKLDKLKEELQEAQQGSNKLQTQVDAAKEQAKTLADLQERMRVTETELKNRCEELEILRAQENPTVEIEATVQKINSEEAEQLRSSLKEREEQLTSLEAELTQLREELETVKRAQAEETQNRVNEADTRCREYTTEIQQLKTSVKEKEDLVASLQAELEKMESTNTVEAEPPFENLEKDARMISLEEELQQIKEEMERMKAKSNELREKNYAAVEALAAAERLSEERLSQAKTAQSAVEQQLSSFQTDARNAFQTLFPHISIETHQTNWLEAFTNEAQKSLTHSPAEQEHMSVSSDVMDLQQKLTLSEDNQRTLQAECEQYRATLSETEGMLKALQKSVEDGELSWTSKISEVEQQKQTALDQVKILEKTIEKINAEMQDTNQLKGQVMLLEAQLEKQLESVTISQIYAEEMAQLKTLLSDTQTQLLSAQADAQQQRAELSQVKMQLEETMSKVQTEEVVPHQMEKPEEEKQSMADLGLTDTEAQQLLDKDKGKSLQEQDTEDSKEGTSV", "length": 978 }, "evidence": [ { "id": "A0A8V0Z8S8", "url": "https://omabrowser.org/oma/group/A0A8V0Z8S8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S8" }, { "id": "PF05104", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosome receptor lysine/proline rich", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 166, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"id": "A0A8V0Z8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 19", "type": "synonym", "evidence": [ { "id": "NP_001012927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012927" } ] }, { "name": "rho-type GTPase-activating protein 19", "type": "synonym", "evidence": [ { "id": "NP_001012927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012927" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851690.1, SRR13267661.20314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000232.1. On Sep 23, 2021 this sequence version replaced NP_001012927.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012927" } ] }, { "annotation": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S9#function" }, { "database": "UniProtKB", "id": "ARBA00055252", "url": "https://www.uniprot.org/uniprotkb/ARBA00055252#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX0#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5", "locus": { "chromosome": "6", "start_pos": 23173871, "end_pos": 23154343, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020759", "url": "https://www.ensembl.org/id/ENSGALG00010020759" } ] } } ], "crossref": [ { "id": "A0A8V0Z8U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423846", "url": "https://www.ncbi.nlm.nih.gov/gene/423846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423846", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQSPANQ", "url": "https://omabrowser.org/oma/group/CQSPANQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8S9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8U5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEL1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZEL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFX0", "url": "https://www.orthodb.org/?gene=A0A8V0ZFX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGAPAAGARRGGSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 495, "header": "tr|A0A8V0Z8U5-1|A0A8V0Z8U5_CHICK Isoform 1 of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0Z8S9-1", "sequence": { "sequence": "ADEGQPEEEARPGGAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 493, "header": "tr|A0A8V0Z8S9-1|A0A8V0Z8U5_CHICK Computationally mapped isoform of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23160873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050213.1", "url": "https://www.ensembl.org/id/ENSGALT00010050213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029670.1", "url": "https://www.ensembl.org/id/ENSGALP00010029670.1" } ] } }, { "isoform_ac": "A0A8V0Z8U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0Z8U5-1", "sequence": { "sequence": "MAAGAPAAGARRGGSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 495, "header": "tr|A0A8V0Z8U5-1|A0A8V0Z8U5_CHICK Isoform 1 of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23154359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050237.1", "url": "https://www.ensembl.org/id/ENSGALT00010050237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029691.1", "url": "https://www.ensembl.org/id/ENSGALP00010029691.1" } ] } }, { "isoform_ac": "A0A8V0ZEL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0ZEL1-1", "sequence": { "sequence": "MAAGAPAAGARRGGSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKDLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 468, "header": "tr|A0A8V0ZEL1-1|A0A8V0ZEL1_CHICK Computationally mapped isoform of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23154359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050220.1", "url": "https://www.ensembl.org/id/ENSGALT00010050220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029677.1", "url": "https://www.ensembl.org/id/ENSGALP00010029677.1" } ] } }, { "isoform_ac": "A0A8V0ZEL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0ZEL6-1", "sequence": { "sequence": "MRWRRERRRPVRGGAAVRPSAILSSAMTPPFAASPSSSIPTSFFCSSCPEGLVIQICELHTQKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 453, "header": "tr|A0A8V0ZEL6-1|A0A8V0ZEL6_CHICK Computationally mapped isoform of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23154354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050230.1", "url": "https://www.ensembl.org/id/ENSGALT00010050230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029687.1", "url": "https://www.ensembl.org/id/ENSGALP00010029687.1" } ] } }, { "isoform_ac": "A0A8V0ZFN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0ZFN5-1", "sequence": { "sequence": "MPLQKLSALIEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 490, "header": "tr|A0A8V0ZFN5-1|A0A8V0ZFN5_CHICK Computationally mapped isoform of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23159142, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050190.1", "url": "https://www.ensembl.org/id/ENSGALT00010050190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029654.1", "url": "https://www.ensembl.org/id/ENSGALP00010029654.1" } ] } }, { "isoform_ac": "A0A8V0ZFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5/entry#A0A8V0ZFX0-1", "sequence": { "sequence": "SSEAICNLVICNDSSLRSQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGAELAQLMGEEDPKLPGANSTASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQVSQLIEYLHKNLRAEGLFRVPGNSIRQQILKDALNSGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHAHLKIADLMLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENITKLNNGVTFMIKHSQKLFKAPAYIRECARLHYLGSRAHTSKDDLDLLTSPGSKELQPLKSQKRSRLDSCHQEETQQRTEEALRELFRHVHNMPDSAKKKKLIRQFNKHPSALTPSSDVATPPAPRRARSRSFSGLIKRKVLGTPVIQERKSRDTTPEPKRVSKENVHLLQKCGSPAHMSQGKLKSLEGQKEESCRRMRAHLLSKDSSSL", "length": 482, "header": "tr|A0A8V0ZFX0-1|A0A8V0ZFX0_CHICK Computationally mapped isoform of Rho GTPase-activating protein 19 OS=Gallus gallus OX=9031 GN=ARHGAP19 PE=4 SV=1 CANONICAL=A0A8V0Z8U5-1" }, "locus": { "chromosome": "6", "start_pos": 23170765, "end_pos": 23161321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050203.1", "url": "https://www.ensembl.org/id/ENSGALT00010050203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029663.1", "url": "https://www.ensembl.org/id/ENSGALP00010029663.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423846", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "F6NW06-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "arhgap19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATEKDTDVNKRDRRGTVCNVVINQESETGSSGEGRPPIIFNPDFFVEKMRHERPEAFTELVLSNITRLIDLPGAEFSQLLGDEEPKTPNAGFFRSFNFLKRKDKGVVFGMPLTEEGIAQIYQLIAYLSKNLHVQGLFRVPGNSLRQQTLREQLNSGADIDFAAGDFHPNDVATLLKSFLGELPEPLLTHRHLHAHLKITELTTFDDEGNKTSFPDKERQIEALQLLLLLLPTANRTLLKLLLDLLYHTAKQQDKNKMSAHNLALMFGPHVIWPKNMNASDLQENLKKLNSGMAFLIKHSQKIFRAPAYLREHARLQFANTKILQSKDDLELLSVSGSPFISACKRSGERVRLDSDNHTEEALKELYRHVTDNMPNSAKKKKLIRQLGKPSTPGTPVNENLTPSSKKHGRSRSFGGLIKRKVLGGQPADRRGRHVSPQSAAGLGKENISSEMAN", "length": 454 }, "evidence": [ { "id": "A0A8V0Z8U5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8U5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GZW4-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "Arhgap19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAEALSGGEAPACNSGRSDAICNFVICNDSPLRGQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPAAGFFRSLMSLKRKEKGVVFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQLLRDALNNGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILPPANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVTANDLQENITKLNTGMAFMIKHSQKLFKAPAYIRECARLYYLGSRTQVSKDDLDLTTSCHALSSQLARSQKRNRVDSCSQQEETQQHTEEALKELFQHVHNMPDSTKKKQLIKQFHKQSLTQTPGQEPSTPRVQKRARSRSFSGLIKRKVLGNQMMSEKKNKSPTPETVAMGELKRVSKENMSLFFSGSPTLKMTPTRLKWSEGKKEGRKGFL", "length": 494 }, "evidence": [ { "id": "A0A8V0Z8U5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8U5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R5V4-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "Arhgap19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEALNGGEAPVCDSDRSDAICNFVICNDSPLRGQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLVDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVVFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQLLRDALNNGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILPPANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVTANDLQENITKLNTGMAFMIKHSQKLFKAPAYIRECARLYYLGSRTQVSKDDLDLTTSCHAMSFQRARPQKQNRVDSYSQQEETQQHTEEALRELFQHVHNLPDSAKKKQLIRQFHKQSLTQTPGREPSTPRVQKRARSRSFSGLIKRKVLGSQMTSEKKNSSPAPESVAMEELKKASKENMNLFFSGSPAVTVTPMRLKWSEAKREGKKGFF", "length": 494 }, "evidence": [ { "id": "A0A8V0Z8U5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8U5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14CB8-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "ARHGAP19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARSRSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRLKWSEGKKEGKKGFL", "length": 494 }, "evidence": [ { "id": "A0A8V0Z8U5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8U5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BRH3-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "Arhgap19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEAPSGGEAPVCDSGRSDAICNFVICNDSPLRGQPIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPAAGFFRSLMSLKRKEKGVVFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQLLRDALNNGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILPPANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVTANDLQENIIKLNTGMAFMIKHSQKLFKAPAYIRECARLYYLGSRTQMSKDDLDLTTSCHNMSFQLARCQRQNRVDPSSQQEETQQHTEEALRELFQHVHNWPDSAKKKQLLRQFHKQSLTQTPGREPSTPRVQKRARSRSFSGLIKRKVLGSQMTSEKKNSSPAPESVAMGELKKASKENMNLFFSGSPAGTVTPTRLKWSEAKREGRKGFF", "length": 494 }, "evidence": [ { "id": "A0A8V0Z8U5", "url": "https://omabrowser.org/oma/group/A0A8V0Z8U5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8U5" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 304, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8T6-1", "uniprot_ac": "A0A8V0Z8T6", "uniprot_id": "A0A8V0Z8T6_CHICK", "mass": { "chemical_mass": 48364.0, "monoisotopic_mass": 48364.0 }, "refseq": { "ac": "XP_015143255", "name": "serpin A3-4-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143255" }, "gene_names": [ { "name": "LOC107049127", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6" } ] }, { "name": "LOC107049127", "type": "synonym", "evidence": [ { "id": "XP_015143255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143255" } ] } ], "protein_names": [ { "name": "Thyroxine-binding globulin", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6/entry#names_and_taxonomy" } ] }, { "name": "Serpin A7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6/entry#names_and_taxonomy" } ] }, { "name": "T4-binding globulin", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6/entry#names_and_taxonomy" } ] }, { "name": "serpin A3-4-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143255" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143255" } ] }, { "annotation": "Major thyroid hormone transport protein in serum.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z313", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z313#function" }, { "database": "UniProtKB", "id": "ARBA00037352", "url": "https://www.uniprot.org/uniprotkb/ARBA00037352#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8T6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107049127", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z8T6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8T6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19957", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19957", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107049127", "url": "https://www.ncbi.nlm.nih.gov/gene/107049127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107049127", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049127", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHSNSYC", "url": "https://omabrowser.org/oma/group/IHSNSYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z313", "url": "https://www.orthodb.org/?gene=A0A8V0Z313", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8T6", "url": "https://www.orthodb.org/?gene=A0A8V0Z8T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { 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{ "sequence": "MVLIYRNMKLLLFLCLLVGIHSNSYPYEPYHQVIRNQNQRGKENRNMPEQAVGNRVCQFACCFYKEISSHENSGNIFFSPLSISTAFAMLTLGARSDTLAQILRVLHFNPRAISENEIHEGYRQLIQMINRKNEGLQLNMGNVLFVLDRLKPQQRFLNSLREFYEGEIYPMNFKRSDQAQTKINDYVAERTNGKIKDLINNLDPLTELLLISYIYFNAEWEKPFNPQYTKKEKFFVDGNKAVEVPMMFGIGAFKHGYDEQLSSTVVQMDYKGGASAFFVLPDQGRMRKLEKKLSCERMARWRTLVSKSNSVNLYLPKFTLHGRYNLKNILYKMGIMDLFTDKADLSGITGQPQHRISQAIHQAVVKVDETGTEAAAATGMEIVPMSVPVVIRMNRPFLLVITLRENILFMGKIVNPLEKD", "length": 420, "header": "tr|A0A8V0Z8T6-1|A0A8V0Z8T6_CHICK Isoform 1 of Thyroxine-binding globulin OS=Gallus gallus OX=9031 GN=LOC107049127 PE=3 SV=1 CANONICAL=A0A8V0Z8T6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z313-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6/entry#A0A8V0Z313-1", "sequence": { "sequence": 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"A0A8V0Z8T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6/entry#A0A8V0Z8T6-1", "sequence": { "sequence": "MVLIYRNMKLLLFLCLLVGIHSNSYPYEPYHQVIRNQNQRGKENRNMPEQAVGNRVCQFACCFYKEISSHENSGNIFFSPLSISTAFAMLTLGARSDTLAQILRVLHFNPRAISENEIHEGYRQLIQMINRKNEGLQLNMGNVLFVLDRLKPQQRFLNSLREFYEGEIYPMNFKRSDQAQTKINDYVAERTNGKIKDLINNLDPLTELLLISYIYFNAEWEKPFNPQYTKKEKFFVDGNKAVEVPMMFGIGAFKHGYDEQLSSTVVQMDYKGGASAFFVLPDQGRMRKLEKKLSCERMARWRTLVSKSNSVNLYLPKFTLHGRYNLKNILYKMGIMDLFTDKADLSGITGQPQHRISQAIHQAVVKVDETGTEAAAATGMEIVPMSVPVVIRMNRPFLLVITLRENILFMGKIVNPLEKD", "length": 420, "header": "tr|A0A8V0Z8T6-1|A0A8V0Z8T6_CHICK Isoform 1 of Thyroxine-binding globulin OS=Gallus gallus OX=9031 GN=LOC107049127 PE=3 SV=1 CANONICAL=A0A8V0Z8T6-1" }, "locus": { "chromosome": "5", "start_pos": 45146267, "end_pos": 45133954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042358.1", "url": "https://www.ensembl.org/id/ENSGALT00010042358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024848.1", "url": "https://www.ensembl.org/id/ENSGALP00010024848.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049127", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049127", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9769733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "resource": "Reactome", "description": "Fibrin formation" }, { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting 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"reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T6" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 416, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z8V4-1", "uniprot_ac": "A0A8V0Z8V4", "uniprot_id": "A0A8V0Z8V4_CHICK", "mass": { "chemical_mass": 168664.0, "monoisotopic_mass": 168664.0 }, "refseq": { "ac": "NP_001264265", "name": "slit homolog 1 protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, "gene_names": [ { "name": "SLIT1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4" } ] }, { "name": "SLIT1", "type": "synonym", "evidence": [ { "id": "NP_001264265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ] } ], "protein_names": [ { "name": "Slit homolog 1 protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4/entry#names_and_taxonomy" } ] }, { "name": "slit homolog 1 protein precursor", "type": "synonym", "evidence": [ { "id": "NP_001264265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ] }, { "name": "slit homolog 1 protein", "type": "synonym", "evidence": [ { "id": "NP_001264265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GU263465.1, SRR13267655.112373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Sep 23, 2021 this sequence version replaced NP_001264265.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ] }, { "annotation": "A novel mechanism whereby N-cadherin acts in concert with Slit-Robo signaling in mediating the placodal cell adhesion required for proper gangliogenesis", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, { "database": "PubMed", "id": "19934013", "url": "https://glygen.org/publication/PubMed/19934013" } ] }, { "annotation": "Axonal projections to the primordium of the anterior crista were reduced 2-3 days after electroporation of either slit1 or slit2 expression plasmids into the anterior pole of the otocyst on embryonic day 3", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, { "database": "PubMed", "id": "24456709", "url": "https://glygen.org/publication/PubMed/24456709" } ] }, { "annotation": "Data show that Slits 1, 2 and 3 expression in the cornea and lens persisted during all stages of cornea innervation, and Robo1 expression was developmentally regulated in trigeminal cell bodies, expressed robustly during nerve ring formation (E5-8).", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, { "database": "PubMed", "id": "22236962", "url": "https://glygen.org/publication/PubMed/22236962" } ] }, { "annotation": "Sclerotome-derived Slit1 drives directional migration and differentiation of Robo2-expressing pioneer myoblasts.", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, { "database": "PubMed", "id": "21653616", "url": "https://glygen.org/publication/PubMed/21653616" } ] }, { "annotation": "Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4#function" }, { "database": "UniProtKB", "id": "ARBA00059139", "url": "https://www.uniprot.org/uniprotkb/ARBA00059139#function" } ] }, { "annotation": "Thus, our data reveal a novel and essential role for Robo2-Slit1 signaling in mediating neural crest-placode interactions during trigeminal gangliogenesis.", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" }, { "database": "PubMed", "id": "18278043", "url": "https://glygen.org/publication/PubMed/18278043" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4", "locus": { "chromosome": "6", "start_pos": 23209081, "end_pos": 23177817, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020778", "url": "https://www.ensembl.org/id/ENSGALG00010020778" } ] } } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395293", "url": "https://www.ncbi.nlm.nih.gov/gene/395293", "database": "GeneID", "categories": [ "Genome Annotation" ] 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"categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051355", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8V4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPPGAASTSGGAAGVPAALRAAAWLLAFVALCRGRAAACPPLCACSGTTVDCHGTALRAVPKSIPRGTERLELNGNNITRIHKNDFSGLKQLRVLQLMENQISVVERGAFDDMKELERLRLNRNQLHTLPELLFQHNQALSRLDLSENFIQAIPRKAFRGATDLKNLQLDKNQISCIEDGAFRALRGLEVLTLNNNNITSIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLAQWLRQRPTIGLFTQCAAPAQLRGLNVAEIQKNEFSCSGQADGVHAQLCSLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKITDLPKGVFGGLFALQLLLLNANKINCVRADAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFVCDCNLKWLADFLRANPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPPKCRCEAGVVECSNLKLTKIPERIPQSTAELRLNNNEISILEATGVFKKLPHLKKINLSNNKVSEIEDGAFEGAASVSELHLTVNQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQISTIAPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQHPDFLRQIPLQDVAFPDFRCEEGQEETSCIPRPQCPQECTCLDTVVRCSNKHLKALPRGIPKNVTELYLDGNQFTQVPGQLSTFKYLQLVDLSNNRISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEGLRSLRLLSLHGNDISTLPEGIFADVTSLSHLAIGANPLYCSCNLRWLSSWVKTGYKEPGIARCAGPPDMEGKLLLTTPAKKFECQGPPSLIVQAKCNPCLSSPCRNQGTCHNDPLGSYRCACPIGYKGRDCEVALDGCSQNPCANGGTCQPQDGDRDGFRCLCAAGFEGPSCRTASDPCKEHSCENGGSCVAAATNYTCLCPAHYTGDFCEQPPDFCSAELSPCQHGSTCIPTSQGPRCECAPGYVGTNCSKDFDDCQDHRCQNNARCVDEVNGYSCLCAEGYSGQLCEMPPHAAGQPGLCERAECQNGAACVERGSRALCQCLPGFGGPKCEKLLSVNFVDRDTYLQFTDLQDWPRANITLQVSTAEDNGILLYNGDSDHMAVELYQGHVRVSYDPGTHPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNSGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQLLNGTSFHGCIRNLYINNELQDFTKTRMTPGVVPGCEPCRKLYCLHGICQPTGAQGPVCHCEPGWDGPHCDQPRGGPCQGHKCVHGLCLPLDALSYSCQCHQGYQGALCNQPSTPPDPCRLLSCHHGRCRLTPGGQPVCECHSGYSGTLCDQEPECHGEPVRDYHQVQRGYAICQTTRPVPYVQCRGTCGGDTDTGCCIGLRPRRRKYAFECSNGATFVEEVEKPSKCGCSPCL", "length": 1544, "header": "tr|A0A8V0Z8V4-1|A0A8V0Z8V4_CHICK Isoform 1 of Slit homolog 1 protein OS=Gallus gallus OX=9031 GN=SLIT1 PE=4 SV=1 CANONICAL=A0A8V0Z8V4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V4/entry#A0A8V0Z8V4-1", "sequence": { "sequence": "MAVPPGAASTSGGAAGVPAALRAAAWLLAFVALCRGRAAACPPLCACSGTTVDCHGTALRAVPKSIPRGTERLELNGNNITRIHKNDFSGLKQLRVLQLMENQISVVERGAFDDMKELERLRLNRNQLHTLPELLFQHNQALSRLDLSENFIQAIPRKAFRGATDLKNLQLDKNQISCIEDGAFRALRGLEVLTLNNNNITSIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLAQWLRQRPTIGLFTQCAAPAQLRGLNVAEIQKNEFSCSGQADGVHAQLCSLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYKKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKITDLPKGVFGGLFALQLLLLNANKINCVRADAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFVCDCNLKWLADFLRANPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPPKCRCEAGVVECSNLKLTKIPERIPQSTAELRLNNNEISILEATGVFKKLPHLKKINLSNNKVSEIEDGAFEGAASVSELHLTVNQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQISTIAPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQHPDFLRQIPLQDVAFPDFRCEEGQEETSCIPRPQCPQECTCLDTVVRCSNKHLKALPRGIPKNVTELYLDGNQFTQVPGQLSTFKYLQLVDLSNNRISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEGLRSLRLLSLHGNDISTLPEGIFADVTSLSHLAIGANPLYCSCNLRWLSSWVKTGYKEPGIARCAGPPDMEGKLLLTTPAKKFECQGPPSLIVQAKCNPCLSSPCRNQGTCHNDPLGSYRCACPIGYKGRDCEVALDGCSQNPCANGGTCQPQDGDRDGFRCLCAAGFEGPSCRTASDPCKEHSCENGGSCVAAATNYTCLCPAHYTGDFCEQPPDFCSAELSPCQHGSTCIPTSQGPRCECAPGYVGTNCSKDFDDCQDHRCQNNARCVDEVNGYSCLCAEGYSGQLCEMPPHAAGQPGLCERAECQNGAACVERGSRALCQCLPGFGGPKCEKLLSVNFVDRDTYLQFTDLQDWPRANITLQVSTAEDNGILLYNGDSDHMAVELYQGHVRVSYDPGTHPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNSGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQLLNGTSFHGCIRNLYINNELQDFTKTRMTPGVVPGCEPCRKLYCLHGICQPTGAQGPVCHCEPGWDGPHCDQPRGGPCQGHKCVHGLCLPLDALSYSCQCHQGYQGALCNQPSTPPDPCRLLSCHHGRCRLTPGGQPVCECHSGYSGTLCDQEPECHGEPVRDYHQVQRGYAICQTTRPVPYVQCRGTCGGDTDTGCCIGLRPRRRKYAFECSNGATFVEEVEKPSKCGCSPCL", "length": 1544, "header": "tr|A0A8V0Z8V4-1|A0A8V0Z8V4_CHICK Isoform 1 of Slit homolog 1 protein OS=Gallus gallus OX=9031 GN=SLIT1 PE=4 SV=1 CANONICAL=A0A8V0Z8V4-1" }, "locus": { "chromosome": "6", "start_pos": 23207542, "end_pos": 23177917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050264.1", "url": "https://www.ensembl.org/id/ENSGALT00010050264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029705.1", "url": "https://www.ensembl.org/id/ENSGALP00010029705.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Robo2-Slit1 dependent cell-cell interactions mediate assembly of the trigeminal ganglion.", "journal": "Nature neuroscience", "date": "2008-03", "authors": "Shiau Celia E, Lwigale Peter Y, Das Raman M, Wilson Stuart A, Bronner-Fraser Marianne", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ], "reference": [ { "type": "PubMed", "id": "18278043", "url": "https://glygen.org/publication/PubMed/18278043" } ] }, { "title": "N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons.", "journal": "Development (Cambridge, England)", "date": "2009-12", "authors": "Shiau Celia E, Bronner-Fraser Marianne", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ], "reference": [ { "type": "PubMed", "id": "19934013", "url": "https://glygen.org/publication/PubMed/19934013" } ] }, { "title": "Sclerotome-derived Slit1 drives directional migration and differentiation of Robo2-expressing pioneer myoblasts.", "journal": "Development (Cambridge, England)", "date": "2011-07", "authors": "Halperin-Barlev Osnat, Kalcheim Chaya", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ], "reference": [ { "type": "PubMed", "id": "21653616", "url": "https://glygen.org/publication/PubMed/21653616" } ] }, { "title": "Nerve repulsion by the lens and cornea during cornea innervation is dependent on Robo-Slit signaling and diminishes with neuron age.", "journal": "Developmental biology", "date": "2012-03-01", "authors": "Schwend Tyler, Lwigale Peter Y, Conrad Gary W", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ], "reference": [ { "type": "PubMed", "id": "22236962", "url": "https://glygen.org/publication/PubMed/22236962" } ] }, { "title": "A subset of chicken statoacoustic ganglion neurites are repelled by\u00a0Slit1 and Slit2.", "journal": "Hearing research", "date": "2014-04", "authors": "Battisti Andrea C, Fantetti Kristen N, Moyers Belle A, Fekete Donna M", "evidence": [ { "database": "RefSeq", "id": "NP_001264265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264265" } ], "reference": [ { "type": "PubMed", "id": "24456709", "url": "https://glygen.org/publication/PubMed/24456709" } ] } ], "pathway": [ { "id": "gga:395293", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395293", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BP10-1", "protein_name": "Slit homolog 1 protein", "gene_name": "SLIT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALTPPRGPSALLVRPALWLLLWAAAWRLGATGCPALCTCAGTTVDCHGTGLRAVPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNLLHTLPELLFQNNQALSRLDLSENTIQAIPRKAFRGATDLKNLQLDKNQIGCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPAGLRGLNVAEVQKSEFSCSGQGEAGRTPSCTLSSGSCPAMCACSNGIVDCRGKGLTAIPANLPEAMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQISEIAPDAFQGLRSLNSLVLYGNKITDLPQGVFGGLFTLQLLLLNANKINCIRLDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRSNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGAEDYQLNSECNSDVVCPHKCRCEASMVECSSLKLTKIPERVPQATAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLEGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQIATISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVASPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLQTLPKGIPKNVTELYLDGNQFTLVPAQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPLDMEGKLLLTTPAKKFECQGPPTLTVQAKCDPCLSSPCQNQGTCRNDPLVGYRCACPSGYKGRDCEVSLDSCSSSPCGNGGTCRSQEGEDAGFTCSCPTGFEGPTCGVDTDDCVEHSCANGGTCVDGVGSYTCQCPLQYSGRACELLVDFCAPDLNPCQHEAQCVGTPDGPRCECAPGYAGGNCTEKQDDCRDHRCQNGAQCVDEANGYSCLCTQGYSGQLCETPPRPPGPRSPCEGTECQNGANCVDQGNGPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSTETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSDAPLYVGGMPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTRMKPGVVPGCEPCRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPADGPCHGHKCVHGKCVPLDALSYSCQCQDGYSGALCNQAGAPADPCEGLRCLHGHCQASATKGTYCVCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICRTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTKCGCALCA", "length": 1534 }, "evidence": [ { "id": "A0A8V0Z8V4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8V4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75093-1", "protein_name": "Slit homolog 1 protein", "gene_name": "SLIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALTPGWGSSAGPVRPELWLLLWAAAWRLGASACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTKCGCALCA", "length": 1534 }, "evidence": [ { "id": "A0A8V0Z8V4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8V4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88279-1", "protein_name": "Slit homolog 1 protein", "gene_name": "Slit1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALTPQRGSSSGLSRPELWLLLWAAAWRLGATACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENSLQAVPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAAQVPACTLSSGSCPAMCSCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYHLNSECTSDVACPHKCRCEASVVECSGLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNKHLQALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCLSSPCQNQGTCHNDPLEVYRCTCPSGYKGRNCEVSLDSCSSNPCGNGGTCHAQEGEDAGFTCSCPSGFEGLTCGMNTDDCVKHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPDLNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQCVDEINSYACLCAEGYSGQLCEIPPAPRNSCEGTECQNGANCVDQGSRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHGKCVPLDALAYSCQCQDGYSGALCNQVGAVAEPCGGLQCLHGHCQASATRGAHCVCSPGFSGELCEQESECRGDPVRDFHRVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKCGCAPCA", "length": 1531 }, "evidence": [ { "id": "A0A8V0Z8V4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8V4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24014-1", "protein_name": "Protein slit", "gene_name": "sli", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQKITPGCALLEGEQQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY", "length": 1504 }, "evidence": [ { "id": "A0A8V0Z8V4", "url": "https://omabrowser.org/oma/group/A0A8V0Z8V4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q80TR4-1", "protein_name": "Slit homolog 1 protein", "gene_name": "Slit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"A0A8V0Z9L0-1", "uniprot_ac": "A0A8V0Z9L0", "uniprot_id": "A0A8V0Z9L0_CHICK", "mass": { "chemical_mass": 59567.0, "monoisotopic_mass": 59567.0 }, "refseq": {}, "gene_names": [ { "name": "ANKDD1A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and death domain containing 1A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKDD1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0", "locus": { "chromosome": "10", "start_pos": 17744949, "end_pos": 17722790, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019185", "url": "https://www.ensembl.org/id/ENSGALG00010019185" } ] } } ], "crossref": [ { "id": "A0A8V0Z9L0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9L0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01670", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01670", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415525", "url": "https://www.ncbi.nlm.nih.gov/gene/415525", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415525", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415525", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFYKWEQ", "url": "https://omabrowser.org/oma/group/RFYKWEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8W7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8X2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9L0", "url": "https://www.orthodb.org/?gene=A0A8V0Z9L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24125", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24125:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24125:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDELASEDDTLLHSEKEFHDAAKRNDTARMEELIKRGVDIKAKNNTDRTALHWAAGAGHVDAVRLLLDHDVPVDDEDSFGMNALLLSAWFGHLRVLHILVNAGAKINCVNKNGRNLLHCAAQRGHIQVMEFIMEDLEDVCVDQTDTMDRTAFHLAAEHGQLEVVEFLIRQGCSHSAKDKEKDTALHLAAKNGHLSVLQKIVDIGVDLDEKNLEGLTCLHLAAEGGHIDCVKLLLEAGADVNAQTQKKMNCLHYAALHGYEEVARILVDAGIHIDAVNHQNASATHIAVLQNFPALVKLLIDAECDLDIPDNRQQTSLHIAAEYGRQDIAEMILIAGVNLKLTDKQGKTSLDVAARGNHINLADMIIKADRFYKWEKDNLNSDSNSWVAKHLTFKQDHRVETQHIRSVMWRLATKYLKPGEWKKLAHYWKFTDAHIRAIEQQWTGTASYREHGHRMLLIWLHGAIMAGENPVKGLYEGLVGIGRRDLAGGRNMSGHRMLLGPASYSDQTLLSSSSTIIWKKKSREGVRNTRLK", "length": 533, "header": "tr|A0A8V0Z9L0-1|A0A8V0Z9L0_CHICK Isoform 1 of Ankyrin repeat and death domain containing 1A OS=Gallus gallus OX=9031 GN=ANKDD1A PE=4 SV=1 CANONICAL=A0A8V0Z9L0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0/entry#A0A8V0Z8W7-1", "sequence": { "sequence": "MGDELASEDDTLLHSEKEFHDAAKRNDTARMEELIKRGVDIKAKNNTDRTALHWAAGAGHVDAVRLLLDHDVPVDDEDSFGMNALLLSAWFGHLRVLHILVNAGAKINCVNKNGRNLLHCAAQRGHIQVMEFIMEDLEDVCVDQTDTMDRTAFHLAAEHGQLEVVEFLIRQGCSHSAKDKEKDTALHLAAKNGHLSVLQKIVDIGVDLDEKNLEGLTCLHLAAEGGHIDCVKLLLEAGADVNAQTQKKMNCLHYAALHGYEEVARILVDAGIHIDAVNHQNASATHIAVLQNFPALVKLLIDAECDLDIPDNRQQTSLHIAAEYGRQDIAEMILIAGVNLKLTDKQGKTSLDVAARGNHINLADMIIKADRFYKWEKDNLNSDSNSWVAKHLTFKQDHRVETQHIRSVMWRLATKYLKPGEWKKLAHYWKFTDAHIRAIEQQWTGTASYREHGHRMLLIWLHGAIMAGENPVKGLYEGLVGIGRRDLAESIRKKANADPASPRKCTAM", "length": 508, "header": "tr|A0A8V0Z8W7-1|A0A8V0Z9L0_CHICK Computationally mapped isoform of Ankyrin repeat and death domain containing 1A OS=Gallus gallus OX=9031 GN=ANKDD1A PE=4 SV=1 CANONICAL=A0A8V0Z9L0-1" }, "locus": { "chromosome": "10", "start_pos": 17735971, "end_pos": 17722825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046388.1", "url": "https://www.ensembl.org/id/ENSGALT00010046388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027620.1", "url": "https://www.ensembl.org/id/ENSGALP00010027620.1" } ] } }, { "isoform_ac": "A0A8V0Z8X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0/entry#A0A8V0Z8X2-1", "sequence": { "sequence": "MGDELASEDDTLLHSEKEFHDAAKRNDTARMEELIKRGVDIKAKNNTDRTALHWAAGAGHVDAVRLLLDHDVPVDDEDSFGMNALLLSAWFGHLRVLHILVNAGAKINCVNKNGRNLLHCAAQRGHIQVMEFIMEDLEDVCVDQTDTMDRTAFHLAAEHGQLEVVEFLIRQGCSHSAKDKEKDTALHLAAKNGHLSVLQKIVDIGVDLDEKNLEGLTCLHLAAEGGHIDCVKLLLEAGADVNAQTQKKMNCLHYAALHGYEEVARILVDAGIHIDAVNHQNASATHIAVLQNFPALVKLLIDAECDLDIPDNRQQTSLHIAAEYGRQDIAEMILIAGVNLKLTDKQGKTSLDVAARGNHINLADMIIKADRFYKWEKDNLNSDSNSWVAKHLTFKQDHRVETQHIRSVMWRLATKYLKPGEWKKLAHYWKFTDAHIRAIEQQWTGTASYREHGHRMLLIWLHGAIMAGENPVKGLYEGLVGIGRRDLADATGDRTMTRHCQTKWCQRQHST", "length": 511, "header": "tr|A0A8V0Z8X2-1|A0A8V0Z8X2_CHICK Computationally mapped isoform of Ankyrin repeat and death domain containing 1A OS=Gallus gallus OX=9031 GN=ANKDD1A PE=4 SV=1 CANONICAL=A0A8V0Z9L0-1" }, "locus": { "chromosome": "10", "start_pos": 17741107, "end_pos": 17722825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046399.1", "url": "https://www.ensembl.org/id/ENSGALT00010046399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027625.1", "url": "https://www.ensembl.org/id/ENSGALP00010027625.1" } ] } }, { "isoform_ac": "A0A8V0Z9L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0/entry#A0A8V0Z9L0-1", "sequence": { "sequence": "MGDELASEDDTLLHSEKEFHDAAKRNDTARMEELIKRGVDIKAKNNTDRTALHWAAGAGHVDAVRLLLDHDVPVDDEDSFGMNALLLSAWFGHLRVLHILVNAGAKINCVNKNGRNLLHCAAQRGHIQVMEFIMEDLEDVCVDQTDTMDRTAFHLAAEHGQLEVVEFLIRQGCSHSAKDKEKDTALHLAAKNGHLSVLQKIVDIGVDLDEKNLEGLTCLHLAAEGGHIDCVKLLLEAGADVNAQTQKKMNCLHYAALHGYEEVARILVDAGIHIDAVNHQNASATHIAVLQNFPALVKLLIDAECDLDIPDNRQQTSLHIAAEYGRQDIAEMILIAGVNLKLTDKQGKTSLDVAARGNHINLADMIIKADRFYKWEKDNLNSDSNSWVAKHLTFKQDHRVETQHIRSVMWRLATKYLKPGEWKKLAHYWKFTDAHIRAIEQQWTGTASYREHGHRMLLIWLHGAIMAGENPVKGLYEGLVGIGRRDLAGGRNMSGHRMLLGPASYSDQTLLSSSSTIIWKKKSREGVRNTRLK", "length": 533, "header": "tr|A0A8V0Z9L0-1|A0A8V0Z9L0_CHICK Isoform 1 of Ankyrin repeat and death domain containing 1A OS=Gallus gallus OX=9031 GN=ANKDD1A PE=4 SV=1 CANONICAL=A0A8V0Z9L0-1" }, "locus": { "chromosome": "10", "start_pos": 17740879, "end_pos": 17722825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046392.1", "url": "https://www.ensembl.org/id/ENSGALT00010046392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027622.1", "url": "https://www.ensembl.org/id/ENSGALP00010027622.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415525", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415525", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8Z7-1", "protein_name": "Ankyrin repeat and death domain containing 1A", "gene_name": "Ankdd1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEELSWETHGLLPLERQLHEASRNNQVGKMKELLGKRVNIRARNHVGRVALHWAAGGGHEQAVRLLLEHGAAVDDVDSFGMTALLLSAWFGHLQIVQILVNAGARVHWESKDGLTLLHCAAQKGHMPVLAFIMEDLEDVALDHADKLGRTAFHRAAEHGQLDALDFLVGSGCDHSVKDKDGNTALHLAASQGHMDVLQRLVDIGLDLEEQNTEGLTALHAAAEGIHADCVVFLLSAGSNVNALTQKGLSCFHYAARSGSEDMSRALVKAGGRTDVADKGTTPMHLAVKHNFPGLVQLLIEAHSDLDAMDIRQQTPLHLAAEHAWQDVAEMLLIAGADLSLRDKQGKTALAVAARSNHISLVDMIIKADRFYRWEKDHLSCRDDSDLSRKNLTFKQDHRQETQQLRSVLWRLASRYLRPNEWKKLAYSWQFTEAHVCAIEQQWTGTRSYQEHGHRMLLIWLHGVATAGKNPSKALFEDLMAIGRRDLAESTRKMANGEPTAPRRCTVM", "length": 508 }, "evidence": [ { "id": "A0A8V0Z9L0", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VQ39-1", "protein_name": "Ankyrin repeat and death domain containing 1A", "gene_name": "Ankdd1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "LVLPLERQLHEASRWNQVERMKELFEKRVNIRARNHVGRVALHWAAGAGHEQAVRLLLERGAAVDDVDSFGMNSLLLSAWFGHLQIVQILVNAGAKVHCESKDGLTLLHCAAQKGHVPVLAFVMEDLEDVALDHADKLGRTAFHRAAEHGQLDALDFLVGSGCDHSVKDKGGNTALHLAASQGHVDVLQRLVDIGLDLEEQNTEGLTALHAAAEGIHADCVMLLLGAGSNVNALTQKRLSCLHYAALGGSEDLSRALIKAGGCTNVADKQGTTPMHLAVKHNFPGLVQLLIDGHSDLDAVDIRRQTPLHLAAEHAWQDVADMLLIAGADLSLRDKQGKTALAVAARSNHVSLVDMIIKADRFYRWEKQDHRQETQQLRSVLWRLASRYLRPNEWKKLAYSWQFTEAHVCAIEQQWTGTRSYQEHGHRMLLIWLHGVAAAGENPSKALFEGLVAIGRRDLAESTRNMANGEPTAPRRCTAM", "length": 480 }, "evidence": [ { "id": "A0A8V0Z9L0", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q495B1-5", "protein_name": "Ankyrin repeat and death domain-containing protein 1A", "gene_name": "ANKDD1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEELAWETDGLLPLERQLHEAARQNNVGRMQELIGRRVNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSLSFKQDHRQETQQLRSVLWRLASRYLQPREWKKLAYSWEFTEAHVDAIEQQWTGTRSYQEHGHRMLLIWLHGVATAGENPSKALFEGLVAIGRRDLAGWSTMARSQLTATSASRVQMILVPQPPE", "length": 522 }, "evidence": [ { "id": "A0A8V0Z9L0", "url": "https://omabrowser.org/oma/group/A0A8V0Z9L0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L0" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 488, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 492, "end_pos": 494 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"protein_names": [ { "name": "Angio-associated migratory cell protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z8Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5#function" }, { "database": "UniProtKB", "id": "ARBA00059273", "url": "https://www.uniprot.org/uniprotkb/ARBA00059273#function" }, { "database": "UniProtKB", "id": "A0A8V0ZAI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAI3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AAMP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5", 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"https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Z5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAI3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"MEPADGPGALDFHGDEEIIEVVELGPPGPDDLAAEMEDVDFEDEGAEEPDGEAWETEDDEGLEDGMEAQDDSEVTFSLHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFESLLGCIWHKDSVTCAGFSHDSVFVATGDMSGLIKVWRVDTKEEAWSFEVGDLEWMEWHPQAHVLLAGTADGNSWMWKIPSGDCKTFQGPACPATCGKILPDGKRAVVGYEDGTMRIWDLKQGTSLHVLKGQDGHQDPLTCVASNQDGSLILTGSVDCHAKLVNSATGKVVCVFKMESAAPKAPASEGEEAESNSVESLGFCNVMPLAAVGYLDGTLAIYDLSTQSLRHKCQHESGIVQLLWEENSAVVYTCSLDGAVRLWDARSGKMISEYRGHSAEILDFAVNKDASIVVTTSGDHQAKVFCVQRPDR", "length": 427, "header": "tr|A0A8V0Z8Z5-1|A0A8V0Z8Z5_CHICK Isoform 1 of Angio-associated migratory cell protein OS=Gallus gallus OX=9031 GN=AAMP PE=1 SV=1 CANONICAL=A0A8V0Z8Z5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5/entry#A0A8V0Z8Z5-1", "sequence": { "sequence": "MEPADGPGALDFHGDEEIIEVVELGPPGPDDLAAEMEDVDFEDEGAEEPDGEAWETEDDEGLEDGMEAQDDSEVTFSLHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFESLLGCIWHKDSVTCAGFSHDSVFVATGDMSGLIKVWRVDTKEEAWSFEVGDLEWMEWHPQAHVLLAGTADGNSWMWKIPSGDCKTFQGPACPATCGKILPDGKRAVVGYEDGTMRIWDLKQGTSLHVLKGQDGHQDPLTCVASNQDGSLILTGSVDCHAKLVNSATGKVVCVFKMESAAPKAPASEGEEAESNSVESLGFCNVMPLAAVGYLDGTLAIYDLSTQSLRHKCQHESGIVQLLWEENSAVVYTCSLDGAVRLWDARSGKMISEYRGHSAEILDFAVNKDASIVVTTSGDHQAKVFCVQRPDR", "length": 427, "header": "tr|A0A8V0Z8Z5-1|A0A8V0Z8Z5_CHICK Isoform 1 of Angio-associated migratory cell protein OS=Gallus gallus OX=9031 GN=AAMP PE=1 SV=1 CANONICAL=A0A8V0Z8Z5-1" }, "locus": { "chromosome": "7", "start_pos": 22192437, "end_pos": 22189164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046450.1", "url": "https://www.ensembl.org/id/ENSGALT00010046450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027653.1", "url": "https://www.ensembl.org/id/ENSGALP00010027653.1" } ] } }, { "isoform_ac": 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"id": "ENSGALP00010027659.1", "url": "https://www.ensembl.org/id/ENSGALP00010027659.1" } ] } }, { "isoform_ac": "A0A8V0ZGG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5/entry#A0A8V0ZGG1-1", "sequence": { "sequence": "MEVASDDLAAEMEDVDFEDEGAEEPDGEAWETEDDEGLEDGMEAQDDSEVTFSLHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECSGHKDSVTCAGFSHDSVFVATGDMSGLIKVWRVDTKEEAWSFEVGDLEWMEWHPQAHVLLAGTADGNSWMWKIPSGDCKTFQGPACPATCGKILPDGKRAVVGYEDGTMRIWDLKQGTSLHVLKGQDGHQDPLTCVASNQDGSLILTGSVDCHAKLVNSATGKVVCVFKMESAAPKAPASEGEEAESNSVESLGFCNVMPLAAVGYLDGTLAIYDLSTQSLRHKCQHESGIVQLLWEENSAVVYTCSLDGAVRLWDARSGKMISEYRGHSAEILDFAVNKDASIVVTTSGDHQAKVFCVQRPDR", "length": 399, "header": "tr|A0A8V0ZGG1-1|A0A8V0ZGG1_CHICK Computationally mapped isoform of Angio-associated migratory cell protein OS=Gallus gallus OX=9031 GN=AAMP PE=1 SV=1 CANONICAL=A0A8V0Z8Z5-1" }, "locus": { "chromosome": "7", "start_pos": 22192437, "end_pos": 22188741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046458.1", "url": "https://www.ensembl.org/id/ENSGALT00010046458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027657.1", "url": "https://www.ensembl.org/id/ENSGALP00010027657.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-177929", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-177929", "resource": "Reactome", "description": "Signaling by EGFR" }, { "id": "R-GGA-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z5", "url": 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420, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7/entry#names_and_taxonomy" } ] }, { "name": "Ran-binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L. Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN. Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1. Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7#function" }, { "database": "UniProtKB", "id": "ARBA00056716", "url": "https://www.uniprot.org/uniprotkb/ARBA00056716#function" }, { "database": "UniProtKB", "id": "A0A8V0ZES2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RANBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7", "locus": { "chromosome": "15", "start_pos": 1339734, "end_pos": 1325800, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020833", "url": "https://www.ensembl.org/id/ENSGALG00010020833" } ] } } ], "crossref": [ { "id": "A0A8V0Z8Z7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z8Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Z7", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZES2", "url": "https://www.orthodb.org/?gene=A0A8V0ZES2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RGAAGQNGPPGVTAPTAPRSRSALRAPDFGPRAALPAALLGQLLQHLLALPPLLGQLLLVGHGPQRGDHVGDPLAEGLRGLGPGPGPLLLPPLPRHGVGLGFGRPHAEGAALPGGAVEDPHGLVPLLLALERHEGERLLAEELYLVRAQPVLGEELLHVVKPDILREEAHEEHDTSTENADDSNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPLMELRPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKAKFEECRNEVDKRAKKAGTDKNDSADKVAEKLEELSVKEESKEAEKKETKENEEKQ", "length": 370, "header": "tr|A0A8V0Z8Z7-1|A0A8V0Z8Z7_CHICK Isoform 1 of Ran-specific GTPase-activating protein OS=Gallus gallus OX=9031 GN=RANBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8Z7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7/entry#A0A8V0Z8Z7-1", "sequence": { "sequence": "RGAAGQNGPPGVTAPTAPRSRSALRAPDFGPRAALPAALLGQLLQHLLALPPLLGQLLLVGHGPQRGDHVGDPLAEGLRGLGPGPGPLLLPPLPRHGVGLGFGRPHAEGAALPGGAVEDPHGLVPLLLALERHEGERLLAEELYLVRAQPVLGEELLHVVKPDILREEAHEEHDTSTENADDSNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPLMELRPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKAKFEECRNEVDKRAKKAGTDKNDSADKVAEKLEELSVKEESKEAEKKETKENEEKQ", "length": 370, "header": "tr|A0A8V0Z8Z7-1|A0A8V0Z8Z7_CHICK Isoform 1 of Ran-specific GTPase-activating protein OS=Gallus gallus OX=9031 GN=RANBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8Z7-1" }, "locus": { "chromosome": "15", "start_pos": 1338021, "end_pos": 1329885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050382.1", "url": "https://www.ensembl.org/id/ENSGALT00010050382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029750.1", "url": "https://www.ensembl.org/id/ENSGALP00010029750.1" } ] } }, { "isoform_ac": "A0A8V0ZES2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7/entry#A0A8V0ZES2-1", "sequence": { "sequence": "MEDTPRLWWRGTNGHNEKGQIGLAIPRVNSCALQHVSSTLQHASGDFLKEAHEEHDTSTENADDSNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPLMELRPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKAKFEECRNEVDKRAKKAGTDKNDSADKVAEKLEELSVKEESKEAEKKETKENEEKQ", "length": 252, "header": "tr|A0A8V0ZES2-1|A0A8V0ZES2_CHICK Computationally mapped isoform of Ran-specific GTPase-activating protein OS=Gallus gallus OX=9031 GN=RANBP1 PE=1 SV=1 CANONICAL=A0A8V0Z8Z7-1" }, "locus": { "chromosome": "15", "start_pos": 1338021, "end_pos": 1328930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050387.1", "url": "https://www.ensembl.org/id/ENSGALT00010050387.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029752.1", "url": "https://www.ensembl.org/id/ENSGALP00010029752.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z8Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Z7" }, { "id": "PS50196", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50196" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBD1", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 326, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z921-1", "uniprot_ac": "A0A8V0Z921", "uniprot_id": "A0A8V0Z921_CHICK", "mass": { "chemical_mass": 73998.0, "monoisotopic_mass": 73998.0 }, "refseq": { "ac": "XP_025005827", "name": "transforming growth factor beta activator LRRC32-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005827" }, "gene_names": [ { "name": "LOC107052104", "type": "recommended", "evidence": [ { "id": "A0A8V0Z921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921" } ] }, { "name": "LOC107052104", "type": "synonym", "evidence": [ { "id": "XP_025005827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005827" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 32", "type": "recommended", "evidence": [ { "id": "A0A8V0Z921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921/entry#names_and_taxonomy" } ] }, { "name": "transforming growth factor beta activator LRRC32-like", "type": "synonym", "evidence": [ { "id": "XP_025005827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005827" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005827.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005827" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z921", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107052104", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z921", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z921", "database": "AlphaFoldDB", "categories": [] }, { "id": "107052104", "url": "https://www.ncbi.nlm.nih.gov/gene/107052104", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052104", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052104", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HANWRLM", "url": "https://omabrowser.org/oma/group/HANWRLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z921", "url": "https://www.orthodb.org/?gene=A0A8V0Z921", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z921", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z921-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z921-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSVPGAGCLLLCLLPAILGAQAGGEVKPRPPPCQQNLTKVSCRAAGLHSFPEDLPQGVKHLDLSHNLLQNLSEGCLPALGQLEHLDLRSNLLEAISGPALAQLPWLHSLLLGSNRLHQNYRDNAVAFSALRSIEVLDLSANGLESHMVGGFLSGLTALRVLHLPRNRLSQLPVGIFQGSPQLTELDLSNNYIMDIEEGAFEALRELAVLNLALNSLHCLSSFSLRQLQVLNLSHNALELFGWEEGRGPYLLQVLDLSHNRLLSFPQLPAAHRLVHLNLSHNSITSLDPGSHHPAQFVLRYEEMVSFSTSLSTAASLTRLAELDLSYNCLQLLPLLFFRAMSSLFTLSVAMNCLQNITMELLSRDGDRDSNGTAVWQEDTVLSVRSMDLHGNAIRALPHWFFDALPQLEAIDLGSNSLQPCGSDMGGKSGGGSPEAEPCTAFHSIPHLQHLSLRRNSLTQLPPHTFSRTPLLSLDLSENRGLAVPWAALEGLEHSLQQLWLRGNHMDNSRAEIPCLGELRVLDLSGNRLSLLPTGLFCSPLQTLDVSGNELPVLPEQALMGWTRSLRALCLAENPFQCCELGWLDALQAAGVQLPDLHRARCIHHSITNRTAPLSSRLPWLCPQPWAGSSVLVLAALLGVLLCAGCRVCRLRGQGVGILLPQPQTERVAEGGAAHSDTKV", "length": 680, "header": "tr|A0A8V0Z921-1|A0A8V0Z921_CHICK Isoform 1 of Leucine-rich repeat-containing protein 32 OS=Gallus gallus OX=9031 GN=LOC107052104 PE=4 SV=1 CANONICAL=A0A8V0Z921-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z921-1", "url": 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GN= PE=4 SV=1 CANONICAL=A0A8V0Z951-1" }, "locus": { "chromosome": "3", "start_pos": 18731650, "end_pos": 18730865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042469.1", "url": "https://www.ensembl.org/id/ENSGALT00010042469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024959.1", "url": "https://www.ensembl.org/id/ENSGALP00010024959.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z951" }, { "id": "PF00134", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAP9-1", "uniprot_ac": "A0A8V0ZAP9", "uniprot_id": "A0A8V0ZAP9_CHICK", "mass": { "chemical_mass": 29969.0, "monoisotopic_mass": 29969.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "TatD DNase domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAP9", "database": 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"Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46317:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46317:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z962", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z962-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP9", "url": 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{ "isoform_ac": "A0A8V0Z962-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9/entry#A0A8V0Z962-1", "sequence": { "sequence": "MAAGPVDCHCHLSAPCFQPDVAAVVRAARQAAVAALVTVTEQAGEFRSVLELSDRFPGFVLPCLGVHPVQEVSPEEQRSVTLKDLDAALPLIELYKDKLVAIGEVGLDFTPRFASTDEQKEGQRQVLTKQVELARKLDLPLNVHSRSAGRPTINLLKEQGASKVLLHAFDGKPSVAMEGVKAGYFFSIPPSIIRSDQKQKLVKVLPLESICLETDSPALGPEKQVRNEPKNVYIAAEYIAKIKGIPVEEVIEVTTQNALKVFPRLRNFLQLSFSNI", "length": 276, "header": "tr|A0A8V0Z962-1|A0A8V0ZAP9_CHICK Computationally mapped isoform of TatD DNase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZAP9-1" }, "locus": { "chromosome": "3", "start_pos": 21491348, "end_pos": 21479339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046565.1", "url": "https://www.ensembl.org/id/ENSGALT00010046565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027725.1", "url": "https://www.ensembl.org/id/ENSGALP00010027725.1" } ] } }, { "isoform_ac": "A0A8V0ZAP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9/entry#A0A8V0ZAP9-1", "sequence": { "sequence": "MAAGPVDCHCHLSAPCFQPDVAAVVRAARQAAVAALVTVTEQAGEFRSVLELSDRFPGFVLPCLGVHPVQEVSPEEQRSVTLKDLDAALPLIELYKDKLVAIGEVGLDFTPRFASTDEQKEGQRQVLTKQVELARKLDLPLNVHSRSAGRPTINLLKEQGASKVLLHAFDGKPSVAMEGVKAGYFFSIPPSIIRSDQKQKLVKVLPLESICLETDSPALGPEKQVRNEPKNVYIAAEYIAKIKGIPVEEVIEVTTQNALKVFPRLRNFLQAFAK", "length": 274, "header": "tr|A0A8V0ZAP9-1|A0A8V0ZAP9_CHICK Isoform 1 of TatD DNase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZAP9-1" }, "locus": { "chromosome": "3", "start_pos": 21491348, "end_pos": 21477259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046573.1", "url": "https://www.ensembl.org/id/ENSGALT00010046573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027731.1", "url": "https://www.ensembl.org/id/ENSGALP00010027731.1" } ] } }, { "isoform_ac": "A0A8V0ZGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9/entry#A0A8V0ZGK9-1", "sequence": { "sequence": "MAAGPVDCHCHLSAPCFQPDVAAVVRAARQAAVAALVTVTEQAGEFRSVLELSDRFPGFVLPCLGVHPVQEVSPEEQRSVTLKVGLDFTPRFASTDEQKEGQRQVLTKQVELARKLDLPLNVHSRSAGRPTINLLKEQGASKVLLHAFDGKPSVAMEGVKAGYFFSIPPSIIRSDQKQKLVKVLPLESICLETDSPALGPEKQVRNEPKNVYIAAEYIAKIKGIPVEEVIEVTTQNALKVFPRLRNFLQV", "length": 250, "header": "tr|A0A8V0ZGK9-1|A0A8V0ZGK9_CHICK Computationally mapped isoform of TatD DNase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZAP9-1" }, "locus": { "chromosome": "3", "start_pos": 21491348, "end_pos": 21485430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046546.1", "url": "https://www.ensembl.org/id/ENSGALT00010046546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027714.1", "url": "https://www.ensembl.org/id/ENSGALP00010027714.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0ZAP9" } ], "binding_site_uniprot": 104, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 104, "end_pos": 104, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962#function" }, { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962" }, { "id": "PIRSR005902-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR005902-1" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9#function" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9" }, { "id": "A0A8V0ZGK9", "database": "UniProtKB", "url": 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}, { "evidence": [ { "id": "A0A8V0ZGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK9#function" }, { "id": "A0A8V0ZGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK9" }, { "id": "PIRSR005902-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR005902-1" } ], "binding_site_uniprot": 146, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 146, "end_pos": 146, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962#function" }, { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962" }, { "id": "PIRSR005902-1", "database": "PIR Site Rule", "url": 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"amino_acid": "Arg", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 194, "end_pos": 194, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962#function" }, { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962" }, { "id": "PIRSR005902-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR005902-1" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9#function" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9" } ], "binding_site_uniprot": 215, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 215, "end_pos": 215, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962#function" }, { "id": "A0A8V0Z962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z962" }, { "id": "PIRSR005902-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR005902-1" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9#function" }, { "id": "A0A8V0ZAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP9" }, { "id": "A0A8V0ZGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK9#function" }, { "id": "A0A8V0ZGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK9" } ], "binding_site_uniprot": 9, 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z967-1", "uniprot_ac": "A0A8V0Z967", "uniprot_id": "A0A8V0Z967_CHICK", "mass": { "chemical_mass": 63047.0, "monoisotopic_mass": 63047.0 }, "refseq": { "ac": "XP_025006785", "name": "A-kinase anchor protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006785" }, "gene_names": [ { "name": "AKAP5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ] }, { "name": "AKAP5", "type": "synonym", "evidence": [ { "id": "XP_025006785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006785" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 5", "type": "synonym", "evidence": [ { "id": "XP_025006785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006785" } ] }, { "name": "A-kinase anchoring protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025006785.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025006785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967", "locus": {} } ], "crossref": [ { "id": "423506", "url": "https://www.ncbi.nlm.nih.gov/gene/423506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PCIKFSK", "url": "https://omabrowser.org/oma/group/PCIKFSK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3C6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z967", "url": "https://www.orthodb.org/?gene=A0A8V0Z967", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15182:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15182:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_025006785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z967-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKAAKEIQMENPSELETPSAGTPCPPLEEQAEKPSMLCFKKRKKSCKKGLTTKDACEGASAASEEKNQCISTDPGEAKASAPLRPSRGAWAALKSLTKPRRGQKSSSRKKVSSDSQVQLEMDAEESCAQGLPRKKANTGVKMPCVRFLRGKKKPSPSEVVEESEDSVQANEVMGILNKAIEELEDMVPAEPCDKAESLTPLPAEDVAPAEPCGRAEALSPLPAEDQGTSAEGAGAPCDKAESLSPFLAEDVAPAEPCDKAESLSLLPAQNSAPADPCDKAESLSPLPAEDVTPAEPRGSAEALSPLPAEDVAPAEPCDKAESLSPLPAEDQGMSAGGADADGRSEPSGEPRPDVDEHTECIAQSEITSSEPVNEPLHEKLPEGSPHQSAAQVENREVTPEAPVSTDQPNGTPEITEVQEIARICKELPERDELERNTDLPEECKSEETTMDFSSSSVSKDDATSVQSSSSHQEKPEVNMGTGVGIVITITEAVDSDDADSDQAYEPSPVLHHNKQKGNKKSSGSFDFGQKEGPGASSGAVVEEKGLGDQGHRTSDQYELLLIETASSLVKAAIQSSIEQLVNEMALEQNKHNSFL", "length": 596, "header": "tr|A0A8V0Z967-1|A0A8V0Z967_CHICK Isoform 1 of A-kinase anchoring protein 5 OS=Gallus gallus OX=9031 GN=AKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z967-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967/entry#A0A8V0Z3C6-1", "sequence": { "sequence": "MAKAAKEIQMENPSELETPSAGTPCPPLEEQAEKPSMLCFKKRKKSCKKGLTTKDACEGASAASEEKNQCISTDPGEAKASAPLRPSRGAWAALKSLTKPRRGQKSSSRKKVSSDSQVQLEMDAEESCAQGLPRKKANTGVKMPCVRFLRGKKKPSPSEVVEESEDSVQANEVMGILNKAIEELEDMVPAEPCDKAESLSPLPAEDQGMSAGGADADGRSEPSGEPRPDVDEHTECIAQSEITSSEPVNEPLHEKLPEGSPHQSAAQVENREVTPEAPVSTDQPNGTPEITEVQEIARICKELPERDELERNTDLPEECKSEETTMDFSSSSVSKDDATSVQSSSSHQEKPEVNMGTGVGIVITITEAVDSDDADSDQAYEPSPVLHHNKQKGNKKSSGSFDFGQKEGPGASSGAVVEEKGLGDQGHRTSDQYELLLIETASSLVKAAIQSSIEQLVNEMALEQNKHNSFL", "length": 471, "header": "tr|A0A8V0Z3C6-1|A0A8V0Z3C6_CHICK Computationally mapped isoform of A-kinase anchoring protein 5 OS=Gallus gallus OX=9031 GN=AKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z967-1" }, "locus": { "chromosome": "5", "start_pos": 52431144, "end_pos": 52429357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042481.1", "url": "https://www.ensembl.org/id/ENSGALT00010042481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024971.1", "url": "https://www.ensembl.org/id/ENSGALP00010024971.1" } ] } }, { "isoform_ac": "A0A8V0Z967-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967/entry#A0A8V0Z967-1", "sequence": { "sequence": "MAKAAKEIQMENPSELETPSAGTPCPPLEEQAEKPSMLCFKKRKKSCKKGLTTKDACEGASAASEEKNQCISTDPGEAKASAPLRPSRGAWAALKSLTKPRRGQKSSSRKKVSSDSQVQLEMDAEESCAQGLPRKKANTGVKMPCVRFLRGKKKPSPSEVVEESEDSVQANEVMGILNKAIEELEDMVPAEPCDKAESLTPLPAEDVAPAEPCGRAEALSPLPAEDQGTSAEGAGAPCDKAESLSPFLAEDVAPAEPCDKAESLSLLPAQNSAPADPCDKAESLSPLPAEDVTPAEPRGSAEALSPLPAEDVAPAEPCDKAESLSPLPAEDQGMSAGGADADGRSEPSGEPRPDVDEHTECIAQSEITSSEPVNEPLHEKLPEGSPHQSAAQVENREVTPEAPVSTDQPNGTPEITEVQEIARICKELPERDELERNTDLPEECKSEETTMDFSSSSVSKDDATSVQSSSSHQEKPEVNMGTGVGIVITITEAVDSDDADSDQAYEPSPVLHHNKQKGNKKSSGSFDFGQKEGPGASSGAVVEEKGLGDQGHRTSDQYELLLIETASSLVKAAIQSSIEQLVNEMALEQNKHNSFL", "length": 596, "header": "tr|A0A8V0Z967-1|A0A8V0Z967_CHICK Isoform 1 of A-kinase anchoring protein 5 OS=Gallus gallus OX=9031 GN=AKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z967-1" }, "locus": { "chromosome": "5", "start_pos": 52431144, "end_pos": 52429357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042485.1", "url": "https://www.ensembl.org/id/ENSGALT00010042485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024974.1", "url": "https://www.ensembl.org/id/ENSGALP00010024974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RZ91-1", "protein_name": "Zinc finger and BTB domain-containing protein 25", "gene_name": "ZBTB25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHARTHTSAPAPLVPQLQGARSRGALRRAAGAGSRARAGRGVREPAPPRDVRGAGGAPPARRSRPPACRGGLWVSDAARPLWAAPGSVPPAASRLGRRPAAAPVAGQIATMDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPETVQSSNLYGIQISTTQKTAVKPGLEVKEAPSNNNGNRAAVQGDHPQLQLSLAIGLDDGSADQQRAHPASQALEEHQKPPVSIKQERCDPESVISQSRPSPSSEVTGPTFTESGIKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDLPNRGATEPLQISQVSLISKDTEPVELNCNFSFSRKRKISCTICGHKFLRKSQLLEHMYTHKGFQQVVLHKWIYTGLSGVEERWRGKMHSLYPHLCTW", "length": 518 }, "evidence": [ { "id": "A0A8V0Z967", "url": "https://omabrowser.org/oma/group/A0A8V0Z967/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SA75-1", "protein_name": "A-kinase anchoring protein 5", "gene_name": "AKAP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METTVSEIQVESKDEKRSAEVSPQDERQEEKASMLCFKRRKKATKARKPKAGSDAPEAARKFPPEAGASDQPQPPGGAWVSVKRLITCRKRSDSSKQQKPCKAKVQPESKDADLSKKKAKSRLKIPCIKFSKGGKRSNHSKIIEDSDCSIKVQEEAESLDIKTPVQLDDQATKTKSTLDIREDVSQKDGDEVCESNVNKSITSPGEKVISVELELGTGHSAIPTGTLILEKDIETTEEKPSIHPQQGSPLETSDIEHPLPVVSDVPPLPAVPDQQIVEEARSSILESGPDWKDHESREIVAEESKPKDTELSQESDFQENEITAEKPKPEESKRMEPIAIIITDTEISEFDVKKAKNVPKQFLISIESEQVGVFANDSGFEGRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNTINNLVQ", "length": 427 }, "evidence": [ { "id": "A0A8V0Z967", "url": "https://omabrowser.org/oma/group/A0A8V0Z967/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P24588-1", "protein_name": "A-kinase anchor protein 5", "gene_name": "AKAP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNKINNLLQ", "length": 427 }, "evidence": [ { "id": "A0A8V0Z967", "url": "https://omabrowser.org/oma/group/A0A8V0Z967/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "beta-2 adrenergic receptor binding", "id": "GO:0031698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031698", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "adenylate cyclase binding", "id": "GO:0008179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "glutamate receptor binding", "id": "GO:0035254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "GABA receptor binding", "id": "GO:0050811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z967", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z967" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z968-1", "uniprot_ac": "A0A8V0Z968", "uniprot_id": "A0A8V0Z968_CHICK", "mass": { "chemical_mass": 25210.0, "monoisotopic_mass": 25210.0 }, "refseq": {}, "gene_names": [ { "name": "SNRPB2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z968", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ] } ], "protein_names": [ { "name": "Small nuclear ribonucleoprotein polypeptide B2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z968", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNRPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968", "locus": { "chromosome": "3", "start_pos": 5836453, "end_pos": 5829094, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019263", "url": "https://www.ensembl.org/id/ENSGALG00010019263" } ] } } ], "crossref": [ { "id": "A0A8V0Z968", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z968", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z968", "url": "https://www.orthodb.org/?gene=A0A8V0Z968", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Y2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z968-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIRPNHTIYINNINDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMYAKTDSDIISKMRGTFADKEKRKEKKKAKSLEQSANAANKKIIQGATQNSTSAPGTSPQNQQVPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENECQAGAARDALQGFKITPSHAMKITYAKK", "length": 223, "header": "tr|A0A8V0Z968-1|A0A8V0Z968_CHICK Isoform 1 of Small nuclear ribonucleoprotein polypeptide B2 OS=Gallus gallus OX=9031 GN=SNRPB2 PE=1 SV=1 CANONICAL=A0A8V0Z968-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z968-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968/entry#A0A8V0Z968-1", "sequence": { "sequence": "MDIRPNHTIYINNINDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMYAKTDSDIISKMRGTFADKEKRKEKKKAKSLEQSANAANKKIIQGATQNSTSAPGTSPQNQQVPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENECQAGAARDALQGFKITPSHAMKITYAKK", "length": 223, "header": "tr|A0A8V0Z968-1|A0A8V0Z968_CHICK Isoform 1 of Small nuclear ribonucleoprotein polypeptide B2 OS=Gallus gallus OX=9031 GN=SNRPB2 PE=1 SV=1 CANONICAL=A0A8V0Z968-1" }, "locus": { "chromosome": "3", "start_pos": 5833698, "end_pos": 5829157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046572.1", "url": "https://www.ensembl.org/id/ENSGALT00010046572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027730.1", "url": "https://www.ensembl.org/id/ENSGALP00010027730.1" } ] } }, { "isoform_ac": "A0A8V0Z9Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968/entry#A0A8V0Z9Y2-1", "sequence": { "sequence": "MDIRPNHTIYINNINDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKRKEKKKAKSLEQSANAANKKIIQVPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENECQAGAARDALQGFKITPSHAMKITYAKK", "length": 208, "header": "tr|A0A8V0Z9Y2-1|A0A8V0Z9Y2_CHICK Computationally mapped isoform of Small nuclear ribonucleoprotein polypeptide B2 OS=Gallus gallus OX=9031 GN=SNRPB2 PE=1 SV=1 CANONICAL=A0A8V0Z968-1" }, "locus": { "chromosome": "3", "start_pos": 5833698, "end_pos": 5829157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046568.1", "url": "https://www.ensembl.org/id/ENSGALT00010046568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027727.1", "url": "https://www.ensembl.org/id/ENSGALP00010027727.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "spliceosomal snRNP complex", "id": "GO:0097525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z968", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z968", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z968" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 86, "start_aa": "His", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA51-1", "uniprot_ac": "A0A8V0ZA51", "uniprot_id": "A0A8V0ZA51_CHICK", "mass": { "chemical_mass": 242879.0, "monoisotopic_mass": 242879.0 }, "refseq": { "ac": "XP_004945401", "name": "general transcription factor 3C polypeptide 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945401" }, "gene_names": [ { "name": "GTF3C1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ] }, { "name": "GTF3C1", "type": "synonym", "evidence": [ { "id": "XP_004945401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945401" } ] } ], "protein_names": [ { "name": "Ral transcription factor IIIC subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor 3C polypeptide 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945401" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945401.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945401" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTF3C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51", "locus": { "chromosome": "14", "start_pos": 11992357, "end_pos": 11954229, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019067", "url": "https://www.ensembl.org/id/ENSGALG00010019067" } ] } } ], "crossref": [ { "id": "cd16169", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16169", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416646", "url": "https://www.ncbi.nlm.nih.gov/gene/416646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416646", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIIQDGI", "url": "https://omabrowser.org/oma/group/TIIQDGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z982", "url": "https://www.orthodb.org/?gene=A0A8V0Z982", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA51", "url": "https://www.orthodb.org/?gene=A0A8V0ZA51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15180:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15180:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z982", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z982", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z982-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z982-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALWALLDEVSLEGLDGITLGALWQRLAARTPPFPLPLEPATRQLLWAALSAQPDLRFYLLPRARPPLRLHDRYEEIDLETGILETKRDPLPLDDIYPVHMILDDKDGLQGSCQYFKERVDITDQIRRKDLQPCCTYTEAVEKWGEKLVIVASQDQRYRALIGWEGDPDLKLPDFSYCILERLGRARWQGELQRDLHSGAFKVDAGKIHYHRRVLDRNGLITMQSHVIRLPSGAQQHSILLLLTRFHVDRRSKYDILMEKLSSMLSARPNQIETLGNLREELGLCERTFKRLYQYMMNAGLAKVISIPLQEIQPNGGPYKTKKGTDVMVRCLKLLKEFRKKMEDYHDDDEEEITKVVQPVDIVCERDMLTQAYELIESRGTKGISQAELRLAMNVGKLESRMLCRLLERYKVVKGFMEDEGRQRTTKYISYIFAEESDLNRQFEREKARSEQLATVTLALVPEDSPPLEDAFPGEEDALVSESDNEEEVKYGKKRRKGQKASSGSLLKLSSQDAVHQSTPAKGSKPTAVKSLGKKLPSPPILEEPDEVPDNFSGESSTLETVKQESSLSTCPLIADEDGDMAVIEEVRLEDPKMCDQKKEKRSRAAAAERSRETYRLLKRRNLIVEAVRNLRLIESLFTLQKMVMDQEKQEGVSTKCCKKSIIRLVQKLSQEGLLRIYRTTVIQDGISKKVEFVVHPSVSPSDPLVRSAIEQVRFRISNSSTASRVKVPQTPSSQDHGEEENLGQEAFPESGDTQEGSSKDENNSRADKTDEKMGVTQLKNYHPVTVPGLGRFLGFLPKMPRLRIVHMFLWYLIYGHPLNGTDRKRSGDGKKKGSKQRPSVNEAQADGTIQVMKTVTNPEIAAQDSEVELSNQTVYVDDTSWMRYVPPLPVHREFGFGWALVSDILLCLPLSLFVQIVQVSYKVDGLEDFLNDPVKKHTLIRFLPRSVRQQLLYKRRYIFSVVENLQRLCYMGLIQFGPTEKFQEKDQVFVYMKRNAVIVDTTICDPHYNLAQSSRPFERRLYVLNTMQDVENFWFDLQCVCLNTPLGVVRCPRSKKSNPQEEEAALAMEQQSAVDKHNLERKCAMLEYTTGSREVVDDGTIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINKTKKENTVSENRLTVRLQTFLTKHPLPLSTGGNKINILGEPKAGPESVIQKKESIEISQEATQDRNKRVRGGKNQKRKRLRKDTGKPTKKKKKEEKSVEKSKRLRYHDEADQSALQRMTRLRVTWTVQEDVLLMLCRIASHVLNAKVKGPFVPWQVVRDIMHASFEESLDKTSHSVGRRARYIVRNPQTYLNYKVCLAEVYQDKALIDEFMNRENNYEEPQVCAAEFKQFVERLKAKFSSTLGNPKLEIPDTLQELFARFRVMAIGEDTNHTTKEDSLNSVYDIHFLVLQNLIQSTLALSDNQMKSCQSFQTFRLYREYRDDILVKAFLECQKRSLVNRRRVNHTLGPKKSRALPFVAMSYQLSQSYYRVFTWRFPSTICTESFQFLQKLKDIGKSDQPDSFLFKDQESKASEGMITFPMDGPGGHCVAMLSLFSLGLVSVNVRIPEQIVVVDSTMVENEVIKSLGKDGLEEEEEEEDDLDDSSGGKRRIEVKARQASHTNYLLMRGYYAPGIVSTRNLSPSDNIVVNSCQVKVKLRCTPLPGRLSSPVSSQLDNMAVGVSSLPKTFTRLIKIQEENYNVDQFLRECTECYGYNPRDVAAVLEIRNAIEAASHFGVCKAELGKQFCSYEEEEPARTRNLQQYIQDLIEMQQVLEVGGNSIRLVAVVFAKPWLLHSVCPMNKPEDSGQQCADTAFPEAQQDCLLSAAKKGEECSGEEEQLGEDTNHPSDEEPPRKRCRTQNDGLQDGDQLCQGLQSGLLSANESHLDADITDPVTMKESFIPDGEMGSLGGTKHTAEGPSDVVSVDVPKDQDKPCSEDKQLEAGNDDLSPEHKHILSLEHSATEQHDDVSHLQENPEVSKGSSVPGLSQAAADGACENVCFIGRPWRIVDGNLNKPVCKGMMEAVLYHIMTKPGITEGMLLQHYTGTLQPVAVLEILQGLEALGCIRRFHMKAAPAVSLFSQPLIAEQLHSPRLSEASAAYYEPTMDCTLRLGGVFPTEVNWNKWVQVIHV", "length": 2143, "header": "tr|A0A8V0ZA51-1|A0A8V0ZA51_CHICK Isoform 1 of Ral transcription factor IIIC subunit 1 OS=Gallus gallus OX=9031 GN=GTF3C1 PE=4 SV=1 CANONICAL=A0A8V0ZA51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z982-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51/entry#A0A8V0Z982-1", "sequence": { "sequence": "MEALWALLDEVSLEGLDGITLGALWQRLAARTPPFPLPLEPATRQLLWAALSAQPDLRFYLLPRARPPLRLHDRYEEIDLETGILETKRDPLPLDDIYPVHMILDDKDGLQGSCQYFKERVDITDQIRRKDLQPCCTYTEAVEKWGEKLVIVASQDQRYRALIGWEGDPDLKLPDFSYCILERLGRARWQGELQRDLHSGAFKVDAGKIHYHRRVLDRNGLITMQSHVIRLPSGAQQHSILLLLTRFHVDRRSKYDILMEKLSSMLSARPNQIETLGNLREELGLCERTFKRLYQYMMNAGLAKVISIPLQEIQPNGGPYKTKKGTDVMVRCLKLLKEFRKKMEDYHDDDEEEITKVVQPVDIVCERDMLTQAYELIESRGTKGISQAELRLAMNVGKLESRMLCRLLERYKVVKGFMEDEGRQRTTKYISYIFAEESDLNRQFEREKARSEQLATVTLALVPEDSPPLEDAFPGEEDALVSESDNEEEVKYGKKRRKGQKASSGSLLKLSSQDAVHQSTPAKGSKPTAVKSLGKKLPSPPILEEPDEVPDNFSGESSTLETVKQESSLSTCPLIADEDGDMAVIEEVRLEDPKMCDQKKEKRSRAAAAERSRETYRLLKRRNLIVEAVRNLRLIESLFTLQKMVMDQEKQEGVSTKCCKKSIIRLVQKLSQEGLLRIYRTTVIQDGISKKVEFVVHPSVSPSDPLVRSAIEQVRFRISNSSTASRVKVPQTPSSQDHGEEENLGQEAFPESGDTQEGSSKDENNSRADKTDEKMGVTQLKNYHPVTVPGLGRFLGFLPKMPRLRIVHMFLWYLIYGHPLNGTDRKRSGDGKKKGSKQRPSVNEAQADGTIQVMKTVTNPEIAAQDSEVELSNQTVYVDDTSWMRYVPPLPVHREFGFGWALVSDILLCLPLSLFVQIVQVSYKVDGLEDFLNDPVKKHTLIRFLPRSVRQQLLYKRRYIFSVVENLQRLCYMGLIQFGPTEKFQEKDQVFVYMKRNAVIVDTTICDPHYNLAQSSRPFERRLYVLNTMQDVENFWFDLQCVCLNTPLGVVRCPRSKKSNPQEEEAALAMEQQSAVDKHNLERKCAMLEYTTGSREVVDDGTIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINKTKKENTVSENRLTVRLQTFLTKHPLPLSTGGNKINILGEPKAGPESVIQKKESIEISQEATQDRNKRVRGGKNQKRKRLRKDTGKPTKKKKKEEKSVEKSKRLRYHDEADQSALQRMTRLRVTWTVQEDVLLMLCRIASHVLNAKVKGPFVPWQVVRDIMHASFEESLDKTSHSVGRRARYIVRNPQTYLNYKVCLAEVYQDKALIDEFMNRENNYEEPQVCAAEFKQFVERLKAKFSSTLGNPKLEIPDTLQELFARFRVMAIGEDTNHTTKEDSLNSVYDIHFLVLQNLIQSTLALSDNQMKSCQSFQTFRLYREYRDDILVKAFLECQKRSLVNRRRVNHTLGPKKSRALPFVAMSYQLSQSYYRVFTWRFPSTICTESFQFLQKLKDIGKSDQPDSFLFKDQESKASEGMITFPMDGPGGHCVAMLSLFSLGLVSVNVRIPEQIVVVDSTMVENEVIKSLGKDGLEEEEEEEDDLDDSSGGKRRIEVKARQASHTNYLLMRGYYAPGIVSTRNLSPSDNIVVNSCQVKVKLRCTPLPGRLSSPVSSQLDNMAVGVSSLPKTFTRLIKIQEENYNVDQFLRECTECYGYNPRDVAAVLEIRNAIEAASHFGVCKAELGKQFCSYEEEEPARTRNLQQYIQDLIEMQQVLEVGGNSIRLVAVVFAKPWLLHSVCPMNKPEDSGQQCADTAFPEAQQDCLLSAAKKGEECSGEEEQLGEDTNHPSDEEPPRKRCRTQNDGLQDGDQLCQGLQSGLLSANESHLDADITDPVTMKESFIPDGEMGSLGGTKHTAEGPSDVVSVDVPKDQDKPCSEDKQLEAGNDDLSPEHKHILSLEHSATEQHDDVSHLQENPEVSKGM", "length": 1994, "header": "tr|A0A8V0Z982-1|A0A8V0ZA51_CHICK Computationally mapped isoform of Ral transcription factor IIIC subunit 1 OS=Gallus gallus OX=9031 GN=GTF3C1 PE=4 SV=1 CANONICAL=A0A8V0ZA51-1" }, "locus": { "chromosome": "14", "start_pos": 11989564, "end_pos": 11954259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046165.1", "url": "https://www.ensembl.org/id/ENSGALT00010046165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027512.1", "url": "https://www.ensembl.org/id/ENSGALP00010027512.1" } ] } }, { "isoform_ac": "A0A8V0ZA51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51/entry#A0A8V0ZA51-1", "sequence": { "sequence": "MEALWALLDEVSLEGLDGITLGALWQRLAARTPPFPLPLEPATRQLLWAALSAQPDLRFYLLPRARPPLRLHDRYEEIDLETGILETKRDPLPLDDIYPVHMILDDKDGLQGSCQYFKERVDITDQIRRKDLQPCCTYTEAVEKWGEKLVIVASQDQRYRALIGWEGDPDLKLPDFSYCILERLGRARWQGELQRDLHSGAFKVDAGKIHYHRRVLDRNGLITMQSHVIRLPSGAQQHSILLLLTRFHVDRRSKYDILMEKLSSMLSARPNQIETLGNLREELGLCERTFKRLYQYMMNAGLAKVISIPLQEIQPNGGPYKTKKGTDVMVRCLKLLKEFRKKMEDYHDDDEEEITKVVQPVDIVCERDMLTQAYELIESRGTKGISQAELRLAMNVGKLESRMLCRLLERYKVVKGFMEDEGRQRTTKYISYIFAEESDLNRQFEREKARSEQLATVTLALVPEDSPPLEDAFPGEEDALVSESDNEEEVKYGKKRRKGQKASSGSLLKLSSQDAVHQSTPAKGSKPTAVKSLGKKLPSPPILEEPDEVPDNFSGESSTLETVKQESSLSTCPLIADEDGDMAVIEEVRLEDPKMCDQKKEKRSRAAAAERSRETYRLLKRRNLIVEAVRNLRLIESLFTLQKMVMDQEKQEGVSTKCCKKSIIRLVQKLSQEGLLRIYRTTVIQDGISKKVEFVVHPSVSPSDPLVRSAIEQVRFRISNSSTASRVKVPQTPSSQDHGEEENLGQEAFPESGDTQEGSSKDENNSRADKTDEKMGVTQLKNYHPVTVPGLGRFLGFLPKMPRLRIVHMFLWYLIYGHPLNGTDRKRSGDGKKKGSKQRPSVNEAQADGTIQVMKTVTNPEIAAQDSEVELSNQTVYVDDTSWMRYVPPLPVHREFGFGWALVSDILLCLPLSLFVQIVQVSYKVDGLEDFLNDPVKKHTLIRFLPRSVRQQLLYKRRYIFSVVENLQRLCYMGLIQFGPTEKFQEKDQVFVYMKRNAVIVDTTICDPHYNLAQSSRPFERRLYVLNTMQDVENFWFDLQCVCLNTPLGVVRCPRSKKSNPQEEEAALAMEQQSAVDKHNLERKCAMLEYTTGSREVVDDGTIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINKTKKENTVSENRLTVRLQTFLTKHPLPLSTGGNKINILGEPKAGPESVIQKKESIEISQEATQDRNKRVRGGKNQKRKRLRKDTGKPTKKKKKEEKSVEKSKRLRYHDEADQSALQRMTRLRVTWTVQEDVLLMLCRIASHVLNAKVKGPFVPWQVVRDIMHASFEESLDKTSHSVGRRARYIVRNPQTYLNYKVCLAEVYQDKALIDEFMNRENNYEEPQVCAAEFKQFVERLKAKFSSTLGNPKLEIPDTLQELFARFRVMAIGEDTNHTTKEDSLNSVYDIHFLVLQNLIQSTLALSDNQMKSCQSFQTFRLYREYRDDILVKAFLECQKRSLVNRRRVNHTLGPKKSRALPFVAMSYQLSQSYYRVFTWRFPSTICTESFQFLQKLKDIGKSDQPDSFLFKDQESKASEGMITFPMDGPGGHCVAMLSLFSLGLVSVNVRIPEQIVVVDSTMVENEVIKSLGKDGLEEEEEEEDDLDDSSGGKRRIEVKARQASHTNYLLMRGYYAPGIVSTRNLSPSDNIVVNSCQVKVKLRCTPLPGRLSSPVSSQLDNMAVGVSSLPKTFTRLIKIQEENYNVDQFLRECTECYGYNPRDVAAVLEIRNAIEAASHFGVCKAELGKQFCSYEEEEPARTRNLQQYIQDLIEMQQVLEVGGNSIRLVAVVFAKPWLLHSVCPMNKPEDSGQQCADTAFPEAQQDCLLSAAKKGEECSGEEEQLGEDTNHPSDEEPPRKRCRTQNDGLQDGDQLCQGLQSGLLSANESHLDADITDPVTMKESFIPDGEMGSLGGTKHTAEGPSDVVSVDVPKDQDKPCSEDKQLEAGNDDLSPEHKHILSLEHSATEQHDDVSHLQENPEVSKGSSVPGLSQAAADGACENVCFIGRPWRIVDGNLNKPVCKGMMEAVLYHIMTKPGITEGMLLQHYTGTLQPVAVLEILQGLEALGCIRRFHMKAAPAVSLFSQPLIAEQLHSPRLSEASAAYYEPTMDCTLRLGGVFPTEVNWNKWVQVIHV", "length": 2143, "header": "tr|A0A8V0ZA51-1|A0A8V0ZA51_CHICK Isoform 1 of Ral transcription factor IIIC subunit 1 OS=Gallus gallus OX=9031 GN=GTF3C1 PE=4 SV=1 CANONICAL=A0A8V0ZA51-1" }, "locus": { "chromosome": "14", "start_pos": 11992299, "end_pos": 11954259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046182.1", "url": "https://www.ensembl.org/id/ENSGALT00010046182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027521.1", "url": "https://www.ensembl.org/id/ENSGALP00010027521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416646", "resource": "KEGG Pathway" }, { "id": "R-GGA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-GGA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BNY8-1", "protein_name": "Ral transcription factor IIIC subunit 1", "gene_name": "GTF3C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPYTQEFLWRALATNPGISFYEEPRERPDLQLQDRYEEIDLETGIVESRRDPVPLEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKMLQPRCTMVEAFGRWGKKLIIVASQDMRYRALIGFEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHSTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHMDRRSKYDILMEKLSTLLSARNNRTETLGKLREELGLCERTFKRLYQYMLNAGLAKVVPLPLKEIHPERGPCKTKKGTDIMVRCLRLLKEFKRKVDDDDDDEDVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYEREKARNELLTTVSLASVQEESLLPEGEDAFLSELDSDEEGGGGGRKRKGRRAPRDARSFSNGGLRTQPHHSTPNKGGWKVINLHPLKKQPSFSPGAAEERASRGAFGGDNLDTSGSSELGMSLGPHCVDSHGGDIAVIEEVRLENSKDSGGSQKTGKHGPGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVQNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRMSNSSTANRMKAPQPPVPQEEAEEESQGEEGPSGSGDAQPSASSKPEGGRVKKTHEKMGVTQLKNYHPVVVPGLGRSLGFLPKMPRLRVIHMFLWYLIYGHPTTVEELSFSERKAGVPSSSRSDLEASFDAAPKDTWEGEVELATETVFVDEASWKRYVPPIPVHKDFGFGWALVSDLLLCLPLSIFTQVVQVSYKVDHLEEFLNDPLKKHTLIRFLPRSIRQQLLYKRRFIFSVVENLQRLCFMGLLQFGPTEKFQDKDQVFVYLKKNVGVVDTTTCDPHYNVARSSRPFERRSYVLNSVQDVENYWFDLQCVCLNTPLGVVRCPRARKSSGPDQGSDEEGRMQKEQENAMDKYTLERKCAMMEYTMGSREVVDEGIIPGDGLGAAGLDSSFYAHLKRNWIWTSYIMDKAKKETTTSENGLTMRLQTFLSKRPMPLGAGGNGRLTVWGDARAGSGLCADRDEHIEVEREPTLERNQKVKGGKSQKRKRLKKDPGKKIKRKKKEELPEDKNKRRYHDEADQSALQRMTRLRVTWSLQEDGLLMLCRIASNVLNTKVKGPFVPWQVVRDILHSTLEESLDKTSLSVGRRARYIIKNPQAYLNYKVCLAEVYQDKALVGEFLSRKGDYGNPKVCASEFKEFVAKLREKFSSALKNPNLEIPDTLEELFARYRVLVIGDKKDQVMKEDELKSVDDIHFLVLQNLIQSTLALSDRQMEICQSFQTFRLYRDYKEQVLVKAFVDYQRRSLVNRRRVNHTLGPKKNRALPFAPMSYQLSQAYHRIFTWRFPSTVCTESFQFFSRLLAAGKRDQADHFSFKDQNCGEPASDLVAFSLDGPGGNCVTALILFSLGLVSVDVRIPEQIVVVDSSMVENEVIKSLGKDSTLEEDEDEEEDLDEGSGAKRRSIEVKAHQASHTNYLLMKGYCVPGIVSNRNLNPNDNIVVNSCLVKFRLRCTPKPTRLALTDPSLEELTVGPSCLPDTFTRLINSPEDTCSLEEFVHQVALSGYQPGDVFAALEIQEAIAAAGCFGVDRLELSKQFFALARTDSERTRTFTDYVQDLLEHQQVLEVGGNTARLVTMANAQPWLLHSVRLKDKDGGADLQRDDHRAKPPEGPSNEDNPPERQAPPSQSPQSTKRRGSWAGADTNSQGGAADPKSALEPPAKRPALQDIRLAPSPGPRAEEELGTLAPALLAAPEDGGASEAGPGDQEGVEVPSFPGQEQLSCQAQLPEAPEDPRGLADGSVAGNLSQVAWERDCESVRFIGRPWRIVDGRLNTPVVKGMMEAVLHHIMTRPGVPESCLLQHYKGVLQPLAVLELLQGLETLGCIKKCVLRKPAAASLFSKPPVGEAPLSLDESPVVFYEPTLDCTIRLGRVFPNEVSWNKWVHL", "length": 2096 }, "evidence": [ { "id": "A0A8V0ZA51", "url": "https://omabrowser.org/oma/group/A0A8V0ZA51/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RFG1-1", "protein_name": "Ral transcription factor IIIC subunit 1", "gene_name": "GTF3C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPYTQEFLWQALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVSLEDVYPIHMILENKDGIQGSCRYFKERKNITKEIRTKALQPRCTMVEAFGRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHSTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGTQQHSILLLLNRFHMDRRSKYDILMEKLSGMLSTRSNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPERGPCKTKKGTDVMVRCLRLLKEFKRKVEDDQDDDEDEEAISKVVPPVDIVYERDMLTQTYELIERRGTKGISQAEVRVAMNVGKLEARMLCRLLQRFKIVKGFMEDEGRQRTTKYISCVFAEESDLSRQYEREKARSELLATVSLASVQEESLLPEAEDAFLSESDSEEEGGRGRGRRRGRGSQADGRSSASGGLGPHSHHSTPTKGGWSVVSLHPLRKQPSSSPGAAEERACRSSAARDSLLDPSSSSDPSVSFGSHCVESHRGDIAVIEEVRLENPKESGGSQKAGKHGPGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKMSQPPAPQGDPEEGSQGGKGPSGSGDCQPNASSTLEGGRVKKSDKKMNVPHLKNYKPVVVPGLGRSLGFLPKMPRLRMVHTFLWYLIYGHPASDTVENLCHGSEKWTRKQEPGRTGVPGSSSDLEDSSAAPSSDTPDRATWESEMELSSETVYVDEASWMRYVPPVPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSFKVDRLDEFLNDPVKKHTLIRFLPRTIRQQLLYKRRYIFSVVESLQRLCYMGLLQFGPTEKFQDKDQVFIYLKKKAVILDTTICDPHYNLARSSRPFERRVYVLNSMQDVENYWFDMQCVCLNTPLGVVRCPRAPKNSGPDQSSDEEGSLQKEQERAVDRHNLERKCAMMEYTTGSREIVDEGLIPGDGLGAAGLDSSFYAHLKRNWIWTSYIINKAKRSNTTENGITVRLQTFLSKRPLPLSARGGSRLNLWGEARAGLELRADREEQVEVDREPTLDRNQRVKGGKSQKRKQVKKDPEKKTKRKKKEEPPEEKIKRPRYHDEADQSALQRMTRLRVTWSIQEDGLIMLCRIASNILNPKVKGPFVPWQVVRDILHSTFEESLDKTSHSVGRRARYIVRNPQAYLNYKVCLAEVYQDKALVGEFMNRKCNYEDPKVCASEFKEFVEKLKEKFSSALKNSSLEIPDTLKELFARYRVLMIADKKDQVRKEDKLNSVDDIHFLVLQNLIQSTLALSDRQMEYCQSFQTFRLYREYKDHVLAKAFMEYQRRSLVNRRRVSHMLGPKKNRALPFVPMSYQLSQAYHRIFTWRFPSSICTESFQFFDKIRAAGKWDRPDNFSFKDQENQDSLSDLVAFSLDGPGGHCVATLTLFSLGLIAVDVRIPEQIVVVDSSLVENEVIKSLGKDGATEEDEDEEEDLDEGSGAKRRSIEVKAPQASHTNYLLMRGYCAPGIVSTRNLNPNDSIVVNSCQVKFWLRSTPAPTRLGPTATPLEELTVGTSCLPDMFTRLVKVPEDTYGLEDFAHQVALSGYKPGDVLAALEIQAAIAAAGCFGVDKVRLSRQFSALEKTDAERTRTFSDYVQDLVEHQQVLEVGSSTTRLVTMASAQPWLLRSVQLKGREEDADPPREDPQARPLEGPSGEDGPSERQASPSQSPRGAKRRASWGNADADSQGGGADPEIAQVPPSKRPACHDMPWAPSPGPRGEEEPETPVSMPPMAPEDPGTREPLPGVSEARQEDVGVPSSPGREQLLEGPEDPRGVADGSAAGSLSQAGQERDPENICFIGRPWRIVDGRLNTPVCKGMMEAVLYQVMTRPGIPESCLLQHYQGVLQPLAVLELLQGLEFLGCIKKRLLRKPRSVSLFSKPAIEEVEAPSSLSENLTVSYEPTLDCTIRLGRVFPSEANWNKWVHL", "length": 2115 }, "evidence": [ { "id": "A0A8V0ZA51", "url": "https://omabrowser.org/oma/group/A0A8V0ZA51/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q12789-2", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "GTF3C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPCTQEFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVALEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKSLQPRCTMVEAFDRWGKKLIIVASQAMRYRALIGQEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSVMLSTRTNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLRLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRNDHDDDEDEEVISKTVPPVDIVFERDMLTQTYDLIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYQREKARSELLTTVSLASMQEESLLPEGEDTFLSESDSEEERSSSKRRGRGSQKDTRASANLRPKTQPHHSTPTKGGWKVVNLHPLKKQPPSFPGAAEERACQSLASRDSLLDTSSVSEPNVSFVSHCADSNSGDIAVIEEVRMENPKESSSSLKTGRHSSGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKTSQPPVPQGEAEEDSQGKEGPSGSGDSQLSASSRSESGRMKKSDNKMGITPLRNYHPIVVPGLGRSLGFLPKMPRLRVVHMFLWYLIYGHPASNTVEKPSFISERRTIKQESGRAGVRPSSSGSAWEACSEAPSKGSQDGVTWEAEVELATETVYVDDASWMRYIPPIPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSYKVDNLEEFLNDPLKKHTLIRFLPRPIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFIFLKKNAVIVDTTICDPHYNLARSSRPFERRLYVLNSMQDVENYWFDLQCVCLNTPLGVVRCPRVRKNSSTDQGSDEEGSLQKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINQAKKENTAAENGLTVRLQTFLSKRPMPLSARGNSRLNIWGEARVGSELCAGWEEQFEVDREPSLDRNRRVRGGKSQKRKRLKKDPGKKIKRKKKGEFPGEKSKRLRYHDEADQSALQRMTRLRVTWSMQEDGLLVLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAYLNYKVCLAEVYQDKALVGDFMNRRGDYDDPKVCANEFKEFVEKLKEKFSSALRNSNLEIPDTLQELFARYRVLAIGDEKDQTRKEDELNSVDDIHFLVLQNLIQSTLALSDSQMKSYQSFQTFRLYREYKDHVLVKAFMECQKRSLVNRRRVNHTLGPKKNRALPFVPMSYQLSQTYYRIFTWRFPSTICTESFQFLDRMRAAGKLDQPDRFSFKDQDNNEPTNDMVAFSLDGPGGNCVAVLTLFSLGLISVDVRIPEQIIVVDSSMVENEVIKSLGKDGSLEDDEDEEDDLDEGVGGKRRSMEVKPAQASHTNYLLMRGYYSPGIVSTRNLNPNDSIVVNSCQMKFQLRCTPVPARLRPAAAPLEELTMGTSCLPDTFTKLINPQENTCSLEEFVLQLELSGYSPEDLTAALEILEAIIATGCFGIDKEELRRRFSALEKAGGGRTRTFADCIQALLEQHQVLEVGGNTARLVAMGSAWPWLLHSVRLKDREDADIQREDPQARPLEGSSSEDSPPEGQAPPSHSPRGTKRRASWASENGETDAEGTQMTPAKRPALQDSNLAPSLGPGAEDGAEAQAPSPPPALEDTAAAGAAQEDQEGVGEFSSPGQEQLSGQAQPPEGSEDPRGFTESFGAANISQAARERDCESVCFIGRPWRVVDGHLNLPVCKGMMEAMLYHIMTRPGIPESSLLRHYQGVLQPVAVLELLQGLESLGCIRKRWLRKPRPVSLFSTPVVEEVEVPSSLDESPMAFYEPTLDCTLRLGRVFPHEVNWNKWIHL", "length": 2109 }, "evidence": [ { "id": "A0A8V0ZA51", "url": "https://omabrowser.org/oma/group/A0A8V0ZA51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63505-1", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "Gtf3c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALVTHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFRRKMEDDHDDDDDEEAISKAVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGKRRGRGSRGHSRASGDAGPGSRPHHSTPAKGGWKVLNLHPLKKPKSAAVERSRRSSACRDGLDTSSSSELNIPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSGQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEGNQEPEVPSRSADSEANTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLRVMHLFLWYLVYGHPASHTGEQPTFHSERKTGKQEPSRPGVQPSSGDDWDSSEAKNSTESSSWEAEMELSTERVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQVVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDVESYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGKADAELCADKEEHFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAFMNYKVCLAEVYQDKALVGDFMSRKDNYEDPKVCAKEFKEFVEKLKEKFSSGLRNPNLEIPDTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTVCTESFQFYDRLRANGILDQPDHFSFKDMDSNDPSSDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDDEEEDLDEGSGTKRQSVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPAPTHLGPTGPTATPLEELQAGPSCLPASFTSLVDPQLHTRCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGVDREKLSRQFSALEKIADKRTRTFLDYIQDLLEQQQVMEVGGNTVRLVAMASAQPWLLPSVRLKDVEIDTKASGDDSQSRLPAGSSIEDHTSEGAPIPPVSSNGTKKRPYCSIQSPETDAEEATRLPAKKPTLQDVCVAASPRPGTEEQTEAQAQFAAPEDAGAEGPRQESQESVGVSGLEQLGCEFQLPENSEDPRGLTESNMAQVAWESGCERVCFVGRPWRGVDGRLNMPVCKGMMEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRMLKKPASVSLFSRPVVEGLGQASEAEALSCQGSTVTFYEPTLDCTIRLGRVFPHDINWKQSGSIYRCVPGQQRSLCPCLIVPPGLSQEPRPSHSCYQSSAQPSTGVATSR", "length": 2148 }, "evidence": [ { "id": "A0A8V0ZA51", "url": "https://omabrowser.org/oma/group/A0A8V0ZA51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K284-1", "protein_name": "General transcription factor 3C polypeptide 1", "gene_name": "Gtf3c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRKMEDDHDDDDDEEVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGGKRRGRGSRGHARASGDAGSGSRPHHSTPAKGGWKVLNLHPLKKPKAAAEERSRRSSACRDGLDTSSSSELNAPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSSQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEENQEPEVPSRSANSDPNTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLKAMHLFLWYLVYGHPAGHTGEQPALHSERKTGKQESSRPGAQPSSGDDWDTSEAKNNTESSSWESEMELSTEIVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQLVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDVECYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGRADAELCADKEEQFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAFMNYKVCLAEVYQDKALVGDFMSRKGNYEDPKVCAKEFKEFVEKLKEKFSSGLRNPNLEIPNTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTICTESFQFYDRLRTNGMLDQPDHFSFKDLDSSDPSNDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDEEEEDLDEGSGTKRQGVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPASTQLGPTGFTATPLEELQAGLSCLPASFTSLVDPQLRTHCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGIDKEKLSRQFSALEKIADRRTRTFLDYIQDLLEQEQVMEVGGNTVRLVTMASAQPWLLHSMRLRDMEVDTKASGDDSQSRLPEGPSIEDHTSEGAAVPPVSSHSTKKRPHCPETDAEEATRLPAKKPTLQDVRVAASPRPGAEEQAEAQAPAQLAAPEDADAGGPRQENQENVGVSGLEQLGCEFQLPEGSEDPRGLTESNMAQAAWESGCERVCFVGRPWRGVDGHLNMPVCKGMLEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRTLRKPASVSLFSRPVVEGLGQASEAEALSCHESTVTFYEPTLDCTIRLGRVFPHDINWNKWIHL", "length": 2101 }, "evidence": [ { "id": "A0A8V0ZA51", "url": "https://omabrowser.org/oma/group/A0A8V0ZA51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" }, { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1476, "end_pos": 1478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1651, "end_pos": 1653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1894, "end_pos": 1896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZA51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" }, { "id": "PF04182", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B-block binding subunit of TFIIIC", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 249, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZA51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" }, { "id": "PF24101", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24101" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GTF3C1 extended winged-helix", "eco_id": "ECO_0000259", "start_pos": 614, "end_pos": 721, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZA51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA51" }, { "id": "PF23704", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23704" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "General transcription factor 3C polypeptide 1 winged-helix", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 61, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 1476, "end_pos": 1478 }, { "start_pos": 1651, "end_pos": 1653 }, { "start_pos": 1894, "end_pos": 1896 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 764, "end_pos": 766 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 873, "end_pos": 875 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z984-1", "uniprot_ac": "A0A8V0Z984", "uniprot_id": "A0A8V0Z984_CHICK", "mass": { "chemical_mass": 49107.0, "monoisotopic_mass": 49107.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tubulin epsilon and delta complex protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z984", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z984", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z984", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR031518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14870:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14870:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z984", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z984-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPAGCGGRLAAALQAALRGGAERRRELERSAERGRDVLWGERRGDERPKAEVGPGGGRESTPSSRELEELELLNAALEKALRVRESVSGAPAAARGAPGAKPAGGAADGGDTGELELPAATRDGPAAACPTCEVRAGSRQPTAAKKPPPYRLRAPYRTDPDVRRTQRKAPAGRVSRAPGAAGKSSSKAVAPKQGGRRGPAVPAAAKPQRTAGFPRSAPSEQHGLPAGDGSSVAVCGQQLSAGKRCCAPLRLPGGAEEHTAGARSASPRAAALQEQGCQLELPLPYRKAHTRNSRAWEKCRLCHTSADAAAARTRFTERIQSSFCSPTPTLSPAEIEKELKALQDVPSRLSLYVEAESADHPTLQREYESLLTLEGLQSTVSQCLHKLQLLRAAVESQRKLHPGCTGDQRDCCAACAAGAWVCGSAGTLAVPLLCYSRLQELRDLFALKLQVSMLHQQIALQKVSL", "length": 466, "header": "tr|A0A8V0Z984-1|A0A8V0Z984_CHICK Isoform 1 of Tubulin epsilon and delta complex protein 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z984-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z984-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z984/entry#A0A8V0Z984-1", "sequence": { "sequence": "MLPAGCGGRLAAALQAALRGGAERRRELERSAERGRDVLWGERRGDERPKAEVGPGGGRESTPSSRELEELELLNAALEKALRVRESVSGAPAAARGAPGAKPAGGAADGGDTGELELPAATRDGPAAACPTCEVRAGSRQPTAAKKPPPYRLRAPYRTDPDVRRTQRKAPAGRVSRAPGAAGKSSSKAVAPKQGGRRGPAVPAAAKPQRTAGFPRSAPSEQHGLPAGDGSSVAVCGQQLSAGKRCCAPLRLPGGAEEHTAGARSASPRAAALQEQGCQLELPLPYRKAHTRNSRAWEKCRLCHTSADAAAARTRFTERIQSSFCSPTPTLSPAEIEKELKALQDVPSRLSLYVEAESADHPTLQREYESLLTLEGLQSTVSQCLHKLQLLRAAVESQRKLHPGCTGDQRDCCAACAAGAWVCGSAGTLAVPLLCYSRLQELRDLFALKLQVSMLHQQIALQKVSL", "length": 466, "header": "tr|A0A8V0Z984-1|A0A8V0Z984_CHICK Isoform 1 of Tubulin epsilon and delta complex protein 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z984-1" }, "locus": { "chromosome": "14", "start_pos": 14230857, "end_pos": 14226259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042509.1", "url": "https://www.ensembl.org/id/ENSGALT00010042509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024999.1", "url": "https://www.ensembl.org/id/ENSGALP00010024999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z986-1", "uniprot_ac": "A0A8V0Z986", "uniprot_id": "A0A8V0Z986_CHICK", "mass": { "chemical_mass": 36747.0, "monoisotopic_mass": 36747.0 }, "refseq": { "ac": "XP_015143930", "name": "annexin A8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143930" }, "gene_names": [ { "name": "ANXA8L1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986" } ] }, { "name": "ANXA8L1", "type": "synonym", "evidence": [ { "id": "XP_015143930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143930" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A8V0Z986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986/entry#names_and_taxonomy" } ] }, { "name": "annexin A8", "type": "synonym", "evidence": [ { "id": "XP_015143930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143930" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143930.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143930" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z986", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANXA8L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z986", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z986", "database": "AlphaFoldDB", "categories": [] }, { "id": "423774", "url": "https://www.ncbi.nlm.nih.gov/gene/423774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423774", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYVEHDV", "url": "https://omabrowser.org/oma/group/CYVEHDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z986", "url": "https://www.orthodb.org/?gene=A0A8V0Z986", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z991", "url": "https://www.orthodb.org/?gene=A0A8V0Z991", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143930", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z986", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z986-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z991", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z991-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWWKAWSEEEGKPVIGVYSNFDPTPDAQTLYKAMKGLGTDEQAIIEVLTKRSNKQRQEIAKSFKAQFGKDLIDSLRSELSGNFERLIVALMYPPYKYEAKELYDAMKGVGTSEDVIIEILASRTKAQIKEIIKAYKEEYGSDLEHDIASETSGYFKQILVCLLQGERDNASLYVDTALARQDAETLFSAGEKIKGTDEIQFITILCKRSATHLLKVFEEYQKLAGKSIEDSIKSETKGSLEDAMLAIVRCTRNIRQYFAERLYHALKGAGTDDGTLIRVIVSRNEVDLNLIKDEFRRIAGQPLSSMIVDDTSGDYKTALLNLCGSD", "length": 327, "header": "tr|A0A8V0Z986-1|A0A8V0Z986_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA8L1 PE=1 SV=1 CANONICAL=A0A8V0Z986-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z986-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986/entry#A0A8V0Z986-1", "sequence": { "sequence": "MAWWKAWSEEEGKPVIGVYSNFDPTPDAQTLYKAMKGLGTDEQAIIEVLTKRSNKQRQEIAKSFKAQFGKDLIDSLRSELSGNFERLIVALMYPPYKYEAKELYDAMKGVGTSEDVIIEILASRTKAQIKEIIKAYKEEYGSDLEHDIASETSGYFKQILVCLLQGERDNASLYVDTALARQDAETLFSAGEKIKGTDEIQFITILCKRSATHLLKVFEEYQKLAGKSIEDSIKSETKGSLEDAMLAIVRCTRNIRQYFAERLYHALKGAGTDDGTLIRVIVSRNEVDLNLIKDEFRRIAGQPLSSMIVDDTSGDYKTALLNLCGSD", "length": 327, "header": "tr|A0A8V0Z986-1|A0A8V0Z986_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA8L1 PE=1 SV=1 CANONICAL=A0A8V0Z986-1" }, "locus": { "chromosome": "6", "start_pos": 18657406, "end_pos": 18645124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050546.1", "url": "https://www.ensembl.org/id/ENSGALT00010050546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029837.1", "url": "https://www.ensembl.org/id/ENSGALP00010029837.1" } ] } }, { "isoform_ac": "A0A8V0Z991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z986/entry#A0A8V0Z991-1", "sequence": { "sequence": "MIHSKGTNITAEITMAWWKAWSEEEGKPVIGVYSNFDPTPDAQTLYKAMKGLGTDEQAIIEVLTKRSNKQRQEIAKSFKAQFGKDLIDSLRSELSGNFERLIVALMYPPYKYEAKELYDAMKGVGTSEDVIIEILASRTKAQIKEIIKAYKEEYGSDLEHDIASETSGYFKQILVCLLQGERDNASLYVDTALARQDAETLFSAGEKIKGTDEIQFITILCKRSATHLLKVFEEYQKLAGKSIEDSIKSETKGSLEDAMLAIVRCTRNIRQYFAERLYHALKGAGTDDGTLIRVIVSRNEVDLNLIKDEFRRIAGQPLSSMIVDDTSGDYKTALLNLCGSD", "length": 341, "header": "tr|A0A8V0Z991-1|A0A8V0Z991_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA8L1 PE=1 SV=1 CANONICAL=A0A8V0Z986-1" }, "locus": { "chromosome": "6", "start_pos": 18659369, "end_pos": 18645124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050552.1", "url": "https://www.ensembl.org/id/ENSGALT00010050552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029842.1", "url": "https://www.ensembl.org/id/ENSGALP00010029842.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423774", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M6L5-1", "protein_name": "Annexin", "gene_name": "LOC100773073", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWWKAWVEQEGVTVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYKYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSNLEEDIQADTSGYLERILVCLLQGSRDDVSGFVDPGLALQDAQDLYAAGEKIHGTDEMKFITILCTRSATHLMRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTRNLHSYFAERLHYAMKGAGTRDGTLIRNIVSRSEIDLNLIKGQFQKMYGKTLSSMIMGDTSGDYKNALLNLVGSDP", "length": 327 }, "evidence": [ { "id": "A0A8V0Z986", "url": "https://omabrowser.org/oma/group/A0A8V0Z986/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SEN1-1", "protein_name": "Annexin", "gene_name": "ANXA8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAWWKAWIEQEGVSVKGSPHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNAQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIIALMYPPYKYEAKELHDAMEGLGTKEGVIIEILASRTKNQLQEIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDLSGFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLMRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTRNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKGQFNKMYGKTLSSMIMEDTSGDYKNALLNLVGSDP", "length": 327 }, "evidence": [ { "id": "A0A8V0Z986", "url": "https://omabrowser.org/oma/group/A0A8V0Z986/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35640-1", "protein_name": "Annexin A8", "gene_name": "Anxa8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWWKAWVEQEGVSVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYSYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGDTSGYLERILVCLLQGSRDDVSGFVDPGLVLQDAQALHEAGEKIMGTDEMKFITILCTRSATHLMRVFEEYEKIANKCIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKGQFKKMYGKTLSSMIMADTSGYYKTALLNLVGTDL", "length": 327 }, "evidence": [ { "id": "A0A8V0Z986", "url": "https://omabrowser.org/oma/group/A0A8V0Z986/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24639-1", "protein_name": "Annexin A7", "gene_name": "nxnA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSYPPNQGYPPQSNSPQPGQYGAPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQGYPPQQGYPPVGVPVGVPVGFAPGMVVGYHQGYFVGTITHDCKHDAEVLRKAMKGIGTNESDLIKVLANRNWAEREQIKREFSAKYSKDLIQDIKSETSGNFEKCLVALLTEPAHFDVEQIHSACAGAGTNENTIIEILVTRSNVQMEYIKQIFKNKHGKSLKDRLESEASGDFKKLLEKLTEPRDESPVINPMQVSKDAEDLYKAGEGKIGTDEKEFIKILTSRSLPHIAAVASEYIKHHKKHSLIKAIDSEFSGSIKTGLIAIVTYALNPYGYFAEILNKSMKGAGTNDNKLIRTVVTQMHNMPQIKTAYSTLFKNSLAHDIQADCSGDFKKLLLDIIS", "length": 462 }, "evidence": [ { "id": "A0A8V0Z986", "url": "https://omabrowser.org/oma/group/A0A8V0Z986/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", 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"MAAYRPGVLVGNWKEEACLEEQERLRDFIQKRERGELLIQKINRLQDNLLKKVQLSVSKDGFICFGDRVMLLSPGKEPSVQRDVEACGELTLAVNLEEVSIYSAVSLHAPCAVSAVTTVGPVGRNTFCILSVDGGSVGEPVKFGQKFGLGTTGGFSDPMLYLASDHKSFMRFAKKSYLQQVFLTDELSYLTCWQATFLDPQLRLEYEGFPVPANCKLIITHCHTNRSLAVPRNFWSRSYFGREYEVICHTYLDSHRAEEDKNYWVIVTGNPGDEGGSMLDRPEPKPGGTGKNEFREEMKNIKIPDYN", "length": 307, "header": "tr|A0A8V0Z994-1|A0A8V0Z994_CHICK Isoform 1 of Cilia and flagella associated protein 161 OS=Gallus gallus OX=9031 GN=CFAP161 PE=4 SV=1 CANONICAL=A0A8V0Z994-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z994-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994/entry#A0A8V0Z994-1", "sequence": { "sequence": "MAAYRPGVLVGNWKEEACLEEQERLRDFIQKRERGELLIQKINRLQDNLLKKVQLSVSKDGFICFGDRVMLLSPGKEPSVQRDVEACGELTLAVNLEEVSIYSAVSLHAPCAVSAVTTVGPVGRNTFCILSVDGGSVGEPVKFGQKFGLGTTGGFSDPMLYLASDHKSFMRFAKKSYLQQVFLTDELSYLTCWQATFLDPQLRLEYEGFPVPANCKLIITHCHTNRSLAVPRNFWSRSYFGREYEVICHTYLDSHRAEEDKNYWVIVTGNPGDEGGSMLDRPEPKPGGTGKNEFREEMKNIKIPDYN", "length": 307, "header": "tr|A0A8V0Z994-1|A0A8V0Z994_CHICK Isoform 1 of Cilia and flagella associated protein 161 OS=Gallus gallus OX=9031 GN=CFAP161 PE=4 SV=1 CANONICAL=A0A8V0Z994-1" }, "locus": { "chromosome": "10", "start_pos": 12175945, "end_pos": 12171287, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046598.1", "url": "https://www.ensembl.org/id/ENSGALT00010046598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027755.1", "url": "https://www.ensembl.org/id/ENSGALP00010027755.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z994", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z994", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z994", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z994", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z994", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z994" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"recommended", "evidence": [ { "id": "A0A8V0Z9B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2" } ] } ], "protein_names": [ { "name": "Small nuclear ribonucleoprotein U11/U12 subunit 25", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNRNP25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2", "locus": { "chromosome": "14", "start_pos": 11995880, "end_pos": 11993140, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019094", "url": "https://www.ensembl.org/id/ENSGALG00010019094" } ] } } ], "crossref": [ { "id": "A0A8V0Z9B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17058", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17058", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9A7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9B2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14942", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14942", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14942:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14942:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVRVCKADGESMRERGGAGRGGAGSCGAAGAERVLPAAVVVVQNASVLDLKKALRRHVQLRQARRGGVQHLSWKYIWRTYHLTYAGEKLADDRKKLREYGIRNRDEVSFIKKLRK", "length": 116, "header": "tr|A0A8V0Z9B2-1|A0A8V0Z9B2_CHICK Isoform 1 of Small nuclear ribonucleoprotein U11/U12 subunit 25 OS=Gallus gallus OX=9031 GN=SNRNP25 PE=4 SV=1 CANONICAL=A0A8V0Z9B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2/entry#A0A8V0Z9A7-1", "sequence": { "sequence": "AAGARRCARAVPGGAGAARAGPAALRPPAAGDAGGDRLSSGAGVRAGHDAVVVVQNASVLDLKKALRRHVQLRQARRGGVQHLSWKYIWRTYHLTYAGEKLADDRKKLREYGIRNRDEVSFIKKLRK", "length": 127, "header": "tr|A0A8V0Z9A7-1|A0A8V0Z9B2_CHICK Computationally mapped isoform of Small nuclear ribonucleoprotein U11/U12 subunit 25 OS=Gallus gallus OX=9031 GN=SNRNP25 PE=4 SV=1 CANONICAL=A0A8V0Z9B2-1" }, "locus": { "chromosome": "14", "start_pos": 11994232, "end_pos": 11993142, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046211.1", "url": "https://www.ensembl.org/id/ENSGALT00010046211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027532.1", "url": "https://www.ensembl.org/id/ENSGALP00010027532.1" } ] } }, { "isoform_ac": "A0A8V0Z9B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2/entry#A0A8V0Z9B2-1", "sequence": { "sequence": "MTVRVCKADGESMRERGGAGRGGAGSCGAAGAERVLPAAVVVVQNASVLDLKKALRRHVQLRQARRGGVQHLSWKYIWRTYHLTYAGEKLADDRKKLREYGIRNRDEVSFIKKLRK", "length": 116, "header": "tr|A0A8V0Z9B2-1|A0A8V0Z9B2_CHICK Isoform 1 of Small nuclear ribonucleoprotein U11/U12 subunit 25 OS=Gallus gallus OX=9031 GN=SNRNP25 PE=4 SV=1 CANONICAL=A0A8V0Z9B2-1" }, "locus": { "chromosome": "14", "start_pos": 11994232, "end_pos": 11993352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046219.1", "url": "https://www.ensembl.org/id/ENSGALT00010046219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027537.1", "url": "https://www.ensembl.org/id/ENSGALP00010027537.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B2" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9B7-1", "uniprot_ac": "A0A8V0Z9B7", "uniprot_id": "A0A8V0Z9B7_CHICK", "mass": { "chemical_mass": 50640.0, "monoisotopic_mass": 50640.0 }, "refseq": { "ac": "XP_015150241", "name": "inactive serine/threonine-protein kinase VRK3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150241" }, "gene_names": [ { "name": "VRK3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ] }, { "name": "VRK3", "type": "synonym", "evidence": [ { "id": "XP_015150241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150241" } ] } ], "protein_names": [ { "name": "VRK serine/threonine kinase 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7/entry#names_and_taxonomy" } ] }, { "name": "inactive serine/threonine-protein kinase VRK3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150241" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150241.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150241" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9B7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9B7", "database": "AlphaFoldDB", "categories": [] }, { "id": "770440", "url": "https://www.ncbi.nlm.nih.gov/gene/770440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VMTLEYE", "url": "https://omabrowser.org/oma/group/VMTLEYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9B7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202670", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202670", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015150241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRGRGRRRAAVGVARDGGAGRVEEQQQQQEEEPPRVCHRVTRFCPQCGGGVEPTFRFCPACGDRLPAPPPPRDAAGPPLQQAPSPAAAAGGVRSEPWPGLSSPAARTPPRPPCAAARRGSSSPRKARPGPAEPLPDGEELRDRGAGRWRLRRLLEQGGCGLLYEAQSASGTCPQKQRFSLKLDVKDSKIYNEQNFFQRAAKKDRVEKWMKLHSLPLLGIPSCVGFGLHADKYRFLVFSDLGRSLQSILNDNLHLSEKAAFQIAVRLLDCLEYLQENEYVHGDITADNIYVNPADLTQVTLAGYYFAFRYCPEGKHVARREGSRTPHEGTVEFISHDSHKGAAPSRRSDLESLGYCLLKWLCGFLPWSEELDKVETVMEKKEMYKNDVTCLLRQCFSRQRSIPDALQSYLQQVMALEYEEKPNYEALRQLFKKPLQMLKASAYDSVDIMIVP", "length": 453, "header": "tr|A0A8V0Z9B7-1|A0A8V0Z9B7_CHICK Isoform 1 of VRK serine/threonine kinase 3 OS=Gallus gallus OX=9031 GN=VRK3 PE=1 SV=1 CANONICAL=A0A8V0Z9B7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7/entry#A0A8V0Z9B7-1", "sequence": { "sequence": "MATRGRGRRRAAVGVARDGGAGRVEEQQQQQEEEPPRVCHRVTRFCPQCGGGVEPTFRFCPACGDRLPAPPPPRDAAGPPLQQAPSPAAAAGGVRSEPWPGLSSPAARTPPRPPCAAARRGSSSPRKARPGPAEPLPDGEELRDRGAGRWRLRRLLEQGGCGLLYEAQSASGTCPQKQRFSLKLDVKDSKIYNEQNFFQRAAKKDRVEKWMKLHSLPLLGIPSCVGFGLHADKYRFLVFSDLGRSLQSILNDNLHLSEKAAFQIAVRLLDCLEYLQENEYVHGDITADNIYVNPADLTQVTLAGYYFAFRYCPEGKHVARREGSRTPHEGTVEFISHDSHKGAAPSRRSDLESLGYCLLKWLCGFLPWSEELDKVETVMEKKEMYKNDVTCLLRQCFSRQRSIPDALQSYLQQVMALEYEEKPNYEALRQLFKKPLQMLKASAYDSVDIMIVP", "length": 453, "header": "tr|A0A8V0Z9B7-1|A0A8V0Z9B7_CHICK Isoform 1 of VRK serine/threonine kinase 3 OS=Gallus gallus OX=9031 GN=VRK3 PE=1 SV=1 CANONICAL=A0A8V0Z9B7-1" }, "locus": { "chromosome": "14", "start_pos": 14284481, "end_pos": 14276754, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042549.1", "url": "https://www.ensembl.org/id/ENSGALT00010042549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025039.1", "url": "https://www.ensembl.org/id/ENSGALP00010025039.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-202670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202670", "resource": "Reactome", "description": "ERKs are inactivated" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LDQ8-1", "protein_name": "Serine/threonine-protein kinase VRK3", "gene_name": "Vrk3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MISFCPVCGKSVQVSFNFCPYCGKALPVEEHAGTQTGNTPLVSSFRGSRKELNFSSKTSPKTVKWSHTVTSLPTTSLSDCDSSESENTLSSPERATGTWSRPPTPRGSPQSSRLSPQTLKRSRVTTSLQALPTGTELTDKKGQHWTLGALQARDDQGILYEAEPTSVLPCEARTRKHRFSLKLDSKDGRLFNEQNFFQRAAKPAQVSKWKKQCMVPLLAIPACVGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHIVSERCVLQVACRLLDALQFLHDNEYVHGNLTAENVFVNPEDLSQVTLVGYGFTFRYCPGGKHVTYKEGSRSPHEGDLEFISVDTHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTSCLPNTEEITRQKQMYQHNPDLFVGLCRRWSKASETLQEYLKVVMALNYEEKPPYAMLRNNLEALLKDLRVSPYDPLDLQMVP", "length": 453 }, "evidence": [ { "id": "A0A8V0Z9B7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9B7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F7F2H0-1", "protein_name": "Serine/threonine-protein kinase VRK3", "gene_name": "Vrk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAQPLLSPPTPEVSAGQLKSMISFCPLCGKSVKVSFKFCPYCGEALPVEEDGGTQTGITPLVSPFRGSKRDLNSSSETSPKKVKWSRTVTSLPLSLHSDYDSSGSDDTLSSPDRATGTRSRSQTPKGSPLANRLSPRTLKRSRVTTSLQALPTGTELTDQNGKHWTLGTLQTRDDQGILYAAEPTSAISSESRTQKWRFSLKLDSKDGRLFNEQNFFQRAAKPLQVNKWKKRCLTPLLAIPTCIGFGVHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCMLQVACRLLDALEYLHEHEYVHGNLTTENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSLHDGDLEFISMDVHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEEITKQKQKYQDNPEPLVGLCGRWNKTSETLREYLKVVMALDYEEKPPYATLRNNLEVLLQNMRVSPYDPLDLQMVP", "length": 474 }, "evidence": [ { "id": "A0A8V0Z9B7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9B7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2YDN8-1", "protein_name": "Serine/threonine-protein kinase VRK3", "gene_name": "VRK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MICPDCGKGIEATFKFCPYCGKPLPAEKHEGSQSFVKPFTSSSQGSRRKTNTSSETSSKKVKWCSYAASPSLPLPSEGKSSGSEDTLSTSGKPKGHLSRSPTPRSSPQTTRQSPQTLKRSRMTASLEALPVGTVLTDKSGQHWKLRCLQTRDDQGILYEAESDSTTGSESSPQKQRFSLKLDAKDGRLFNEQNFFQRAAKPLQVNKWKKLYSIPQLAIPTCIGFGVHQDKYRFLVFPTLGRSLQSILDDFPKHVMSVRSVFQMACRLLDALEFLHENEYVHGNVTAENIFVNPENLCQVTLAGYGFTFRYSPGGRHVAYTEGSRSPHEGHLEFISMDLHKGCGPSRRSDLQTLGYCLLKWLYGTLPWTNCLPNTEEIVKLKQKFLDNPEGLVGQCSRWITPSETLQEYLKVVMALQYEEKPPYSTLRNELEALLQDLRASAYDPLDLQVVP", "length": 451 }, "evidence": [ { "id": "A0A8V0Z9B7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9B7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IV63-1", "protein_name": "Serine/threonine-protein kinase VRK3", "gene_name": "VRK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISFCPDCGKSIQAAFKFCPYCGNSLPVEEHVGSQTFVNPHVSSFQGSKRGLNSSFETSPKKVKWSSTVTSPRLSLFSDGDSSESEDTLSSSERSKGSGSRPPTPKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKDGRLFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGLPMVP", "length": 474 }, "evidence": [ { "id": "A0A8V0Z9B7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9B7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3G5-1", "protein_name": "Serine/threonine-protein kinase VRK3", "gene_name": "Vrk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISFCPVCGKSVKVSFKFCPYCGKALPVEEDGGTQSAVTPHVSSVPGSRRDLNSSFETSPKKVKCSHTVTSLPLSRHSDCDSSGSDNTLTSPDRATGTRSRPLTPKGSPLSNRQSPQTLKRTRVTTSLQALATGTELTDQNGKHWTLGALQIRDDQGILYEAEPTSAVPSESRTQKWRFSLKLDSKDGRLFNEQNFFQRVAKPLQVNKWKKQFLLPLLAIPTCIGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKASETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSPYDPLDLQMVP", "length": 453 }, "evidence": [ { "id": "A0A8V0Z9B7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9B7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9B7" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 432, "start_aa": "Trp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9C3-1", "uniprot_ac": "A0A8V0Z9C3", "uniprot_id": "A0A8V0Z9C3_CHICK", "mass": { "chemical_mass": 38199.0, "monoisotopic_mass": 38199.0 }, "refseq": { "ac": "XP_015139347", "name": "SERTA domain-containing protein 4 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139347" }, "gene_names": [ { "name": "SERTAD4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3" } ] }, { "name": "SERTAD4", "type": "synonym", "evidence": [ { "id": "XP_015139347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139347" } ] } ], "protein_names": [ { "name": "SERTA domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3/entry#names_and_taxonomy" } ] }, { "name": "SERTA domain-containing protein 4 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015139347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139347" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139347.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERTAD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3", "locus": { "chromosome": "3", "start_pos": 22395812, "end_pos": 22402999, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018894", "url": "https://www.ensembl.org/id/ENSGALG00010018894" } ] } } ], "crossref": [ { "id": "A0A8V0Z9C3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9C3", "database": "AlphaFoldDB", "categories": [] }, { "id": "421383", "url": "https://www.ncbi.nlm.nih.gov/gene/421383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421383", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSHQVDY", "url": "https://omabrowser.org/oma/group/CSHQVDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9C3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14272:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14272:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLVLPMQRLGRPSAAEGTADLAAYRALWEPPACGRPGPAAPGPGPGPAPVAAGPPAAGSHYRGISNPAAASKIAYFKRKYVEEEDFHPPLSSCAHKTISVFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIVMQNNWCFSACSFGAASPQEWFVPQDCPYRKRLRMAKEEYEKLHTCCFYQECGSHYLNLPYSVNASTENTSSSSPSSSSSPISLPSCSQQVDYDIGSAPSYRSDEQIPASEIFVTNARPHANQDKAKFTDEKGGDEPERDDVPLNCEPVRGTHAFECKGKFYDYFETGCNDKSDVSESWKKSLRKKESLPSNKMCCSKGSKI", "length": 345, "header": "tr|A0A8V0Z9C3-1|A0A8V0Z9C3_CHICK Isoform 1 of SERTA domain containing 4 OS=Gallus gallus OX=9031 GN=SERTAD4 PE=4 SV=1 CANONICAL=A0A8V0Z9C3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3/entry#A0A8V0Z9C3-1", "sequence": { "sequence": "MTLVLPMQRLGRPSAAEGTADLAAYRALWEPPACGRPGPAAPGPGPGPAPVAAGPPAAGSHYRGISNPAAASKIAYFKRKYVEEEDFHPPLSSCAHKTISVFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIVMQNNWCFSACSFGAASPQEWFVPQDCPYRKRLRMAKEEYEKLHTCCFYQECGSHYLNLPYSVNASTENTSSSSPSSSSSPISLPSCSQQVDYDIGSAPSYRSDEQIPASEIFVTNARPHANQDKAKFTDEKGGDEPERDDVPLNCEPVRGTHAFECKGKFYDYFETGCNDKSDVSESWKKSLRKKESLPSNKMCCSKGSKI", "length": 345, "header": "tr|A0A8V0Z9C3-1|A0A8V0Z9C3_CHICK Isoform 1 of SERTA domain containing 4 OS=Gallus gallus OX=9031 GN=SERTAD4 PE=4 SV=1 CANONICAL=A0A8V0Z9C3-1" }, "locus": { "chromosome": "3", "start_pos": 22401946, "end_pos": 22397934, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045674.1", "url": "https://www.ensembl.org/id/ENSGALT00010045674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027232.1", "url": "https://www.ensembl.org/id/ENSGALP00010027232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421383", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PS78-1", "protein_name": "SERTA domain-containing protein 4 isoform X1", "gene_name": "sertad4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALVLSMNPFCEPETESPPPIFQPIWESEHCSKSCVSNPSPPGGEPQGLMEEPHYRRAPDHVMNRVAVSRISYFKRKFVEDEEPVLSFRSYCHTQVSPVLEERAHILRLSLEKLRFMDDPESFLRRSVLINNLLRRLRNEILLQSDWCFPSGPTTTPCPLQTPAANTSLSPPALQPCITPPGSYRKRLRLMRKEGPECVPACCCLYAAGRYLQLPLSVYEREVYSNSHPSSSTSSSSSSSSSVRFPQLMEDEDEEDSDDEEEDSVCPVLAMCQAETREQNRTWDSLRSQSHRDDKILEKEREKGKERVKGGEVSQRWLSDTIGTRHHGTLARAHIRGK", "length": 338 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LNP9-1", "protein_name": "SERTA domain containing 4", "gene_name": "Sertad4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "KNGQGVWAGCGERFVRCSPCHGRAARVGSGLRAGAARAAPRAEAERGRRQGGRGRGAPRSGRAEGGGERACQVPSRPGGIQQSQARKSAGKWQTGLTGFSRSSPDTAAHFHNRLRRRRDLRGPRPPRTGPRRQGPGGAWAAAAARRTAAAGAQGARFCEPIVSEGAAEIAGYHTLWEADSYGGASPPGPAHVPSQGDRGAGPQLAGSHYRGISNPVSTPKVTYFKRKYAEEEELPTPLSSCSHKTISIFEERAHILYMSLEKLRFIDDPEVYLRRSVLINNLMKRIHGEIVMQNSWYLPACSLSGTSAQEWFLAQDCPYRKRPRVAKQEWEKFHTCCFYQECGGHCLNLPLSVSDGVGSASAAAVASPASSSSSPSTSSPSSPSSSSSSLSSPLPLPSCSHHVDFDVGSAPIYKSQVPASEIFVTNVRSLGVQEKIKFNSDGKVSHETSRDGNALGQEPVGNDLDFECKGQFYDYFETGYTERNRMSESWKKSLRKKELSPSNKLCCSRGGKM", "length": 513 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7DTG3-1", "protein_name": "SERTA domain-containing protein 4", "gene_name": "Sertad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGASPPGPAPVPSQGDRGASSHLAGSHYRGIPNPISTPKVTYFKRKYAEDEDLHPPLSSCSHKTISIFEERAHILYMSLEKLRFIDDPEVYLRRSVLINNLMKRIHGEIVMQNSWCLPACSLGGTPAQEWFLAQDCPYRKRPRVAKEEWEKIHTCCFYQECGGHCLNLPLSVNTSVGSTSAAAVASAASSSSSPSTSSSSSPSSSSSPSPSPSSSSSSSSSSPLPLPSCSHHVDFDIGSAPIYKSQIPASEIFVTNIRSLGVQEKVKFNNDGKVSHETSRDGDALGQEPVGNDLDFECKGQFYDYFETGYNERNRVSESWKKSLRKKELSPSSKLCCNRGGKM", "length": 377 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B7X4-1", "protein_name": "SERTA domain containing 4", "gene_name": "SERTAD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGLSPPGPAQAPLQGDRGAGPPLAGSHYRGISNPITTSKITYFKRKYVEEEDFHPPLSSCSHKTISIFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIIMQNNWCFPACSFNGASAQEWFMAQDCPYRKRPRMAKEECEKFHACCLYQECGGHYLNLPLSVNANVGSASTTASSSSPSSSSSSSPPLPLPSCSQQVDFDIGSAPVYKGDGQIPASEIFVTNVRSLGVQEKAKLNDEKVNDDTNRDGGPLSHGPVGNDLAFEGKGQFYDYFETGYNEKSNVSESWKKSLRKKEPSPSNKLCCSKGSKI", "length": 352 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LUP4-1", "protein_name": "SERTA domain containing 4", "gene_name": "SERTAD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGPSPPGPAQAPLQGDRGAGPPLAGSHYRGISNPITTSKITYFKRKYVEEEDFHPPLSSCSHKTISIFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIIMQNNWCFPACSFNGASAQEWFMAQDCPYRKRPRMAKEECEKFHACCFYQECGGHYLNLPLSVNANVGSASSSSSSSSSSSPSPPPPLPSCSHQVDFDVGSTPLYKGDGQIPANEIFVTNARSLGVQEKAKLNDEKADDDTSRDGGPLNHEPVGHDLAFECKGQFYDYFETGYNEKNNVSESWKKSIRKKEPSPSNKLCCSKGSKI", "length": 349 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NUC0-1", "protein_name": "SERTA domain-containing protein 4", "gene_name": "SERTAD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGPSPPGPAQAPLQGDRGAGPPLAGSHYRGISNPITTSKITYFKRKYVEEEDFHPPLSSCSHKTISIFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIIMQNNWCFPACSFNGTSAQEWFMAQDCPYRKRPRMAKEECEKFHACCFYQECGGHYLNLPLSVNANVGSASTAASSPSASSSSSSSSSSPPLPLPSCSRQVDFDVGSASIYKSDGQIPANEIFVTNVRSLGVQEKAKLNDEKANDDTNRDGGPLSHEPVGNDLAFECKGQFYDYFETGYNERNNVNESWKKSLRKKEASPPSNKLCCSKGSKI", "length": 356 }, "evidence": [ { "id": "A0A8V0Z9C3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9C3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9C3" }, { "id": "PS51053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SERTA", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 147, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9D2-1", "uniprot_ac": "A0A8V0Z9D2", "uniprot_id": "A0A8V0Z9D2_CHICK", "mass": { "chemical_mass": 5313.0, "monoisotopic_mass": 5313.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9D2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z9D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "CGSGAVRCRCSRCFCFPSKRRLRERPRVLPLLSVPEDAVLHAVPSPSC", "length": 48, "header": "tr|A0A8V0Z9D2-1|A0A8V0Z9D2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9D2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D2/entry#A0A8V0Z9D2-1", "sequence": { "sequence": "CGSGAVRCRCSRCFCFPSKRRLRERPRVLPLLSVPEDAVLHAVPSPSC", "length": 48, "header": "tr|A0A8V0Z9D2-1|A0A8V0Z9D2_CHICK Isoform 1 of 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9E4-1", "uniprot_ac": "A0A8V0Z9E4", "uniprot_id": "A0A8V0Z9E4_CHICK", "mass": { "chemical_mass": 81171.0, "monoisotopic_mass": 81171.0 }, "refseq": {}, "gene_names": [ { "name": "POLN", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ] } ], "protein_names": [ { "name": "DNA-directed DNA polymerase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4", "locus": { "chromosome": "4", "start_pos": 82487638, "end_pos": 82411358, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017619", "url": "https://www.ensembl.org/id/ENSGALG00010017619" } ] } } ], "crossref": [ { "id": "A0A8V0Z9E4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9E4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08638", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08638", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10133:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10133:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADGEKNLAAPPKRKQEVPTYCLGKKRLLVKKHISHERRYNWTSRQAEPSENVFCDIRSLGYEEKRDLIANIKEAVAFVTTMIFLDGSSQLNSEQTLTSSVKGIVVLVKSRTDRLSSLSFSSTDSTWSAASQGDKFIYLETECSSLWEQGEQTHNKFARQVLFQILRCKVPVICFNAKDFLKTVLQVYGNGISWKQVADSIVLDPRIAAWLINSSDTVPSFECLLQYFEKSYSVETVNTDTGALRNSRHQNLVVNLQKLYTIMMGLAHDLQVQGLWKLFCTLELPLIKVLAVMETHKIHVDKQELKKTSEILGLRLKELEEEAHQIAGERFLLTSSSQLREVLFEKLKLHTLCEKIPRTERQQVASTSEVVLSKLQDLHPLPKLMLEYRQVRKMKSTYVDGLRTCMRKGFICPTWNQTGTVTGRLSSKHPNIQGISKHPVRITKKQYIKGKEEEILTISPRALFVSKKGYTFLAADFSQIELRILADLSAEPELLKLFQEPETTDIFTSLASQWKGIPSEQVKQTDREQAKRIVYSVVYGAGKERLAECLGITPHEAGHFIESFMQKYKKVHEFTKKTIGQCQNKGYVVSIMGRKRLLANINSQDYKLRTQAERQAVNFVVQGSAADLCKMAMVEIFTSVVVSPTLTARLIAQIHDELLFEVEDSQIQEFSALVKRTMESLQQTTALEVPLKVPLKVLLTTGKSWGCMTELQEM", "length": 714, "header": "tr|A0A8V0Z9E4-1|A0A8V0Z9E4_CHICK Isoform 1 of DNA-directed DNA polymerase OS=Gallus gallus OX=9031 GN=POLN PE=3 SV=1 CANONICAL=A0A8V0Z9E4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4/entry#A0A8V0Z9E4-1", "sequence": { "sequence": "MADGEKNLAAPPKRKQEVPTYCLGKKRLLVKKHISHERRYNWTSRQAEPSENVFCDIRSLGYEEKRDLIANIKEAVAFVTTMIFLDGSSQLNSEQTLTSSVKGIVVLVKSRTDRLSSLSFSSTDSTWSAASQGDKFIYLETECSSLWEQGEQTHNKFARQVLFQILRCKVPVICFNAKDFLKTVLQVYGNGISWKQVADSIVLDPRIAAWLINSSDTVPSFECLLQYFEKSYSVETVNTDTGALRNSRHQNLVVNLQKLYTIMMGLAHDLQVQGLWKLFCTLELPLIKVLAVMETHKIHVDKQELKKTSEILGLRLKELEEEAHQIAGERFLLTSSSQLREVLFEKLKLHTLCEKIPRTERQQVASTSEVVLSKLQDLHPLPKLMLEYRQVRKMKSTYVDGLRTCMRKGFICPTWNQTGTVTGRLSSKHPNIQGISKHPVRITKKQYIKGKEEEILTISPRALFVSKKGYTFLAADFSQIELRILADLSAEPELLKLFQEPETTDIFTSLASQWKGIPSEQVKQTDREQAKRIVYSVVYGAGKERLAECLGITPHEAGHFIESFMQKYKKVHEFTKKTIGQCQNKGYVVSIMGRKRLLANINSQDYKLRTQAERQAVNFVVQGSAADLCKMAMVEIFTSVVVSPTLTARLIAQIHDELLFEVEDSQIQEFSALVKRTMESLQQTTALEVPLKVPLKVLLTTGKSWGCMTELQEM", "length": 714, "header": "tr|A0A8V0Z9E4-1|A0A8V0Z9E4_CHICK Isoform 1 of DNA-directed DNA polymerase OS=Gallus gallus OX=9031 GN=POLN PE=3 SV=1 CANONICAL=A0A8V0Z9E4-1" }, "locus": { "chromosome": "4", "start_pos": 82486781, "end_pos": 82411557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042580.1", "url": "https://www.ensembl.org/id/ENSGALT00010042580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025070.1", "url": "https://www.ensembl.org/id/ENSGALP00010025070.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9E4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z8P6-1", "A0A8V0XWC6-1", "Q92076-1", "A0A8V0ZUF2-1", "A0A8V0ZBR9-1", "P36195-1", "A0A8V0X4G3-1", "A0A8V0X331-1", "P10399-1", "A0A8V1A4V3-1", "A0A3Q2TTB3-1", "A0A8V0YNB2-1", "A0A8V0XWS0-1", "A0A8V0Y2U3-1", "A0A8V0Z9E4-1" ], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] }, { "id": "R-GGA-6786155", "name": "POLN binds ICL-DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YT00-1", "A0A8V0Z9E4-1" ], "evidence": [ { "id": "R-GGA-6786155", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6786155" } ] }, { "id": "R-GGA-6786166", "name": "Translesion synthesis across unhooked ICL by POLN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"AlphaFoldDB", "categories": [] }, { "id": "416632", "url": "https://www.ncbi.nlm.nih.gov/gene/416632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3L0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3L5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9G3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA80", "url": "https://www.orthodb.org/?gene=A0A8V0ZA80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSDDSSAPEQPRTTISGQMTLTDETLSAVSKSSKNAVKNSDIETANLSPSLIPAQQPTISLISDDNTDALSVESLTLVPPVDSHSIRTFSCIPQPSLQSELEVCKVKEREEECSD", "length": 1040, "header": "tr|A0A8V0ZA80-1|A0A8V0ZA80_CHICK Isoform 1 of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0Z3L0-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSGLAGKDDGGCLVCRRLTVTVDTGFRSSSSSCNRNSRNIHSGRFLHKISKAHKVNRACLVSMLAVVTER", "length": 993, "header": "tr|A0A8V0Z3L0-1|A0A8V0Z3L0_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9015433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046715.1", "url": "https://www.ensembl.org/id/ENSGALT00010046715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027821.1", "url": "https://www.ensembl.org/id/ENSGALP00010027821.1" } ] } }, { "isoform_ac": "A0A8V0Z3L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0Z3L5-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPDDSSAPEQPRTTISGQMTLTDETLSAVSKSSKNAVKNSDIETANLSPSLIPAQQPTISLISDDNTDALSVESLTLVPPVDSHSIRTFSCIPQPSLQSELEVCKVKEREEECSD", "length": 989, "header": "tr|A0A8V0Z3L5-1|A0A8V0Z3L5_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9010790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046729.1", "url": "https://www.ensembl.org/id/ENSGALT00010046729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027826.1", "url": "https://www.ensembl.org/id/ENSGALP00010027826.1" } ] } }, { "isoform_ac": "A0A8V0Z9G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0Z9G3-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSVRSGRKGRRRVFSLSEADSHGGHWV", "length": 952, "header": "tr|A0A8V0Z9G3-1|A0A8V0ZA80_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9015566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046722.1", "url": "https://www.ensembl.org/id/ENSGALT00010046722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027823.1", "url": "https://www.ensembl.org/id/ENSGALP00010027823.1" } ] } }, { "isoform_ac": "A0A8V0ZA80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0ZA80-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSDDSSAPEQPRTTISGQMTLTDETLSAVSKSSKNAVKNSDIETANLSPSLIPAQQPTISLISDDNTDALSVESLTLVPPVDSHSIRTFSCIPQPSLQSELEVCKVKEREEECSD", "length": 1040, "header": "tr|A0A8V0ZA80-1|A0A8V0ZA80_CHICK Isoform 1 of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9010790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046737.1", "url": "https://www.ensembl.org/id/ENSGALT00010046737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027830.1", "url": "https://www.ensembl.org/id/ENSGALP00010027830.1" } ] } }, { "isoform_ac": "A0A8V0ZAY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0ZAY1-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSGSRDTDRCFRKPSCNDTVLCHIATGIVTLSKVCEN", "length": 960, "header": "tr|A0A8V0ZAY1-1|A0A8V0ZAY1_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9018123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046711.1", "url": "https://www.ensembl.org/id/ENSGALT00010046711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027819.1", "url": "https://www.ensembl.org/id/ENSGALP00010027819.1" } ] } }, { "isoform_ac": "A0A8V0ZGV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0ZGV8-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSGLAGKDDGGCLVCRRLTVTVDTGFRSSSSSCNRNSRNIHSARSFSHRFRKK", "length": 976, "header": "tr|A0A8V0ZGV8-1|A0A8V0ZGV8_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9012439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046718.1", "url": "https://www.ensembl.org/id/ENSGALT00010046718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027822.1", "url": "https://www.ensembl.org/id/ENSGALP00010027822.1" } ] } }, { "isoform_ac": "A0A8V0ZGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80/entry#A0A8V0ZGW6-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKASRSIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHMNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQPMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLVNQDKGGERPKISLQVSLYLLSQVFLIIHYAPLVNSLAEVILNGDLSVFSSKAEQDVQKNSAKSSIRCFIKPTETLERSLEINKQKGKKRVQKRPNYKNVGEEDEEERQSEDTQDDLDKTKSTEASSKGIRTSSENEEIEMVIMERCKLSELSISAVTEQNTTDEEKSAAASGSEITNWNRPFLDMVYNALDCAEDDYYALFVLCLLYAMSHNKGIDPVKLERIQLPAQHAEERNSYNHVLAEGLIRIMNYAAQPDGKIRLATLELGCLLLKQLVFSKNGSIIKDVHLACLEGAREESVHLLRRFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTQRAIRVFFMLRSLSLHLQGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGQVQRFLAVDIYQMSLVEPDVARLGWGVVKFAGLLQDMQVTGVEDDSRALNIIIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPVQPSNEVMGFGHSSAAASQHLPFRFYDHARRGSSDPTVQRSVFASVDKVPGFAVAQCINQHHPSPLSSPSPSSGSGSTGRCDSVAASSASTPSVAQSPSDDSSAPEQPRTTISGQMTLTDETLSAVSKSSKNAVKNSDIETANLSPSLIPAQQPTISLISDDNTDALSVESLTLVPPVDSHSIRTFSCIPQPSLQSELEVCKVKEREEECSD", "length": 1038, "header": "tr|A0A8V0ZGW6-1|A0A8V0ZGW6_CHICK Computationally mapped isoform of C-type lectin domain containing 16A OS=Gallus gallus OX=9031 GN=CLEC16A PE=1 SV=1 CANONICAL=A0A8V0ZA80-1" }, "locus": { "chromosome": "14", "start_pos": 9067485, "end_pos": 9010790, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046741.1", "url": "https://www.ensembl.org/id/ENSGALT00010046741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027832.1", "url": "https://www.ensembl.org/id/ENSGALP00010027832.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "negative regulation of autophagosome maturation", "id": "GO:1901097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZA80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" }, { "id": "PF19439", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19439" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CLEC16A/TT9 C-terminal", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 1014, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZA80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA80" }, { "id": "PF09758", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09758" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FPL", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 198, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 919 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 971, "end_pos": 973 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, 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"count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9G8-1", "uniprot_ac": "A0A8V0Z9G8", "uniprot_id": "A0A8V0Z9G8_CHICK", "mass": { "chemical_mass": 119621.0, "monoisotopic_mass": 119621.0 }, "refseq": {}, "gene_names": [ { "name": "LRIG1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" } ] } ], "protein_names": [ { "name": "Leucine rich repeats and immunoglobulin like domains 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" } ], "common_name": "Chicken", "glygen_name": 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Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9G8", "url": "https://www.orthodb.org/?gene=A0A8V0Z9G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-177929", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-177929", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807004", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVMPSRSGGGSALPLLLAVLLGSAAACPDGCVCDEERLRCGGLGLPEVPRELSPGLRHVNLSYNKLTEIDPSAFAELLNLQEVQLNNNELTAIPSLGPAASNVRSLHLHHNRIRSIEASQLKPYVALETLDLSFNDITEIRNGCFPQGLHIKELYLGSNRISTLEPGAFDSLSRSLLTLRLSKNRITQLPVKAFRLPRLTQLELNRNRIRLIEGLTFQGLDSLEVLKLQRNNISKLTDGAFWGLAKMQVLHLDYNSLTEVNSGSLYGLSSLHQLHLSNNSISRINPDGWSFCQKLHELILSYNNLTRLDEGSLADLGGLHVLRLSHNSINHIAEGAFKGLKNLRVLELDHNDISGTIEDTNGAFTGLENLSKLTLFGNKIKSVAKKAFSGLEALEHLNLGDNAIRSIQADAFAKMKSLRQLHINSDSFLCDCQLKWLPPWLLERELQSFVVATCAHPESLKSKSIFAVLPESFVCDDFPKPQIIIQPETTVAVLGKDIRFTCSAASSSSSPMMFAWKKDNEVLHNAEIENFAHVRAKDGEVMEYTTILHLRHVTFAHEGRYQCIITNHFGSTYSNKARLTVNVLPSFIKTPHDITSRTGTTARLECAAEGHPPPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIEDMGVYSCTAQNSAGSVLANATLTVLETPSLIHPLEDHVVSVGETVALQCKATGSPPPRITWLKGDQPLIVTERHHFTSGNQLLVVRNVVLEDAGKYTCEMSNTLGTERAHSHVSILQSLGCRKDRTTVGIITIAVVCSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETIVPPDVPSYLSSQGTLSDRQEAVVRGDNQHPNGHIDSNDGSFVTGMCQTDAGRCPDVEAPTVGCRQPKLCIGYNKDTWKTEDTADGMLVPDKTGYGLPVVCTDCSGSTDSMNIHIYPGEAEYYAEGLQTLDSSYHNALSSKERSRQRGAGTTSLLHPQQCNGIASGKRMEADGTLYPSNHDRITPVSTTSPLLADQHGSSQSGAKPSELNNLNLVRASPAGGSLKQLNVLPEIPPTLLDLQSEAEAKQALLANGFTPTSCDSSHAFKPPSRSTD", 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"MAVMPSRSGGGSALPLLLAVLLGSAAACPDGCVCDEERLRCGGLGLPEVPRELSPGLRHVNLSYNKLTEIDPSAFAELLNLQEVQLNNNELTAIPSLGPAASNVRSLHLHHNRIRSIEASQLKPYVALETLDLSFNDITEIRNGCFPQGLHIKELYLGSNRISTLEPGAFDSLSRSLLTLRLSKNRITQLPVKAFRLPRLTQLELNRNRIRLIEGLTFQGLDSLEVLKLQRNNISKLTDGAFWGLAKMQVLHLDYNSLTEVNSGSLYGLSSLHQLHLSNNSISRINPDGWSFCQKLHELILSYNNLTRLDEGSLADLGGLHVLRLSHNSINHIAEGAFKGLKNLRVLELDHNDISGTIEDTNGAFTGLENLSKLTLFGNKIKSVAKKAFSGLEALEHLNLGDNAIRSIQADAFAKMKSLRQLHINSDSFLCDCQLKWLPPWLLERELQSFVVATCAHPESLKSKSIFAVLPESFVCDDFPKPQIIIQPETTVAVLGKDIRFTCSAASSSSSPMMFAWKKDNEVLHNAEIENFAHVRAKDGEVMEYTTILHLRHVTFAHEGRYQCIITNHFGSTYSNKARLTVNVLPSFIKTPHDITSRTGTTARLECAAEGHPPPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIEDMGVYSCTAQNSAGSVLANATLTVLETPSLIHPLEDHVVSVGETVALQCKATGSPPPRITWLKGDQPLIVTERHHFTSGNQLLVVRNVVLEDAGKYTCEMSNTLGTERAHSHVSILQSLGCRKDRTTVGIITIAVVCSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETIVPPDVPSYLSSQGTLSDRQEAVVRGDNQHPNGHIDSNDGSFVTGMCQTDAGRCPDVEAPTVGCRQPKLCIGYNKDTWKTEDTADGMLVPDKTGYGLPVVCTDCSGSTDSMNIHIYPGEAEYYAEGLQTLDSSYHNALSSKERSRQRGAGTTSLLHPQQCNGIASGKRMEADGTLYPSNHDRITPVSTTSPLLADQHGSSQSGAKPSELNNLNLVRASPAGGSLKQLNVLPEIPPTLLDLQSEAEAKQALLANGFTPTSCDSSHAFKPPSRSTD", "length": 1094, "header": "tr|A0A8V0Z9G8-1|A0A8V0Z9G8_CHICK Isoform 1 of Leucine rich repeats and immunoglobulin like domains 1 OS=Gallus gallus OX=9031 GN=LRIG1 PE=4 SV=1 CANONICAL=A0A8V0Z9G8-1" }, "locus": { "chromosome": "12", "start_pos": 14710351, "end_pos": 14632376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046731.1", "url": "https://www.ensembl.org/id/ENSGALT00010046731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027828.1", "url": "https://www.ensembl.org/id/ENSGALP00010027828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-177929", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-177929", "resource": "Reactome", "description": "Signaling by EGFR" }, { "id": "R-GGA-6807004", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "resource": "Reactome", "description": "Negative regulation of MET activity" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 581, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 671, "end_pos": 673 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9H1-1", "uniprot_ac": "A0A8V0Z9H1", "uniprot_id": "A0A8V0Z9H1_CHICK", "mass": { "chemical_mass": 26234.0, "monoisotopic_mass": 26234.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9H1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNWLAGRSQRVVINGSVSGWGLVTSSFPQGLVLGLVLFNIVINDIDDGIECTLSKFMDDTKLSGAVDTLEGREAIQRDLDRLEKWAHENLMRFNKAKCRVLHLDRDNPRYLYKLGEDLESSPAEKDLGVLVDEKLDMSQQYALAARKANCVLDSIKKGVASREREVIVPLYSALVRPQLEYCIQAWGPQYRKDVELLEQVQRRATRMIRGLEHLSYKERLKELGLFRL", "length": 229, "header": "tr|A0A8V0Z9H1-1|A0A8V0Z9H1_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9H1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1/entry#A0A8V0Z9H1-1", "sequence": { "sequence": "MRNWLAGRSQRVVINGSVSGWGLVTSSFPQGLVLGLVLFNIVINDIDDGIECTLSKFMDDTKLSGAVDTLEGREAIQRDLDRLEKWAHENLMRFNKAKCRVLHLDRDNPRYLYKLGEDLESSPAEKDLGVLVDEKLDMSQQYALAARKANCVLDSIKKGVASREREVIVPLYSALVRPQLEYCIQAWGPQYRKDVELLEQVQRRATRMIRGLEHLSYKERLKELGLFRL", "length": 229, "header": "tr|A0A8V0Z9H1-1|A0A8V0Z9H1_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9H1-1" }, "locus": { "chromosome": "2", "start_pos": 47664509, "end_pos": 47663823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046321.1", "url": "https://www.ensembl.org/id/ENSGALT00010046321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027587.1", "url": "https://www.ensembl.org/id/ENSGALP00010027587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H1" }, { "id": "PF00078", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 112, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9H4-1", "uniprot_ac": "A0A8V0Z9H4", "uniprot_id": "A0A8V0Z9H4_CHICK", "mass": { "chemical_mass": 75201.0, "monoisotopic_mass": 75201.0 }, "refseq": { "ac": "XP_015145313", "name": "coiled-coil domain-containing protein 93 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145313" }, "gene_names": [ { "name": "CCDC93", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ] }, { "name": "CCDC93", "type": "synonym", "evidence": [ { "id": "XP_015145313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145313" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 93", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 93 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145313.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4", "locus": { "chromosome": "7", "start_pos": 28528094, "end_pos": 28495322, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020963", "url": "https://www.ensembl.org/id/ENSGALG00010020963" } ] } } ], "crossref": [ { "id": "A0A8V0Z9H4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9H4", "database": "AlphaFoldDB", "categories": [] }, { "id": "424277", "url": "https://www.ncbi.nlm.nih.gov/gene/424277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424277", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YERQEAP", "url": "https://omabrowser.org/oma/group/YERQEAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9H4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF71", "url": "https://www.orthodb.org/?gene=A0A8V0ZF71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF85", "url": "https://www.orthodb.org/?gene=A0A8V0ZF85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZML3", "url": "https://www.orthodb.org/?gene=A0A8V0ZML3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16441:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16441:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21673", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21673", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZML3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZML3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZML3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZML3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCCPPTGGRGDPWRPRSERSHEAPRSPRPPSPAPPCREWHGPDALVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS", "length": 649, "header": "tr|A0A8V0Z9H4-1|A0A8V0Z9H4_CHICK Isoform 1 of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#A0A8V0Z9H4-1", "sequence": { "sequence": "MLCCPPTGGRGDPWRPRSERSHEAPRSPRPPSPAPPCREWHGPDALVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS", "length": 649, "header": "tr|A0A8V0Z9H4-1|A0A8V0Z9H4_CHICK Isoform 1 of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "locus": { "chromosome": "7", "start_pos": 28526866, "end_pos": 28495462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050686.1", "url": "https://www.ensembl.org/id/ENSGALT00010050686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029929.1", "url": "https://www.ensembl.org/id/ENSGALP00010029929.1" } ] } }, { "isoform_ac": "A0A8V0ZF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#A0A8V0ZF71-1", "sequence": { "sequence": "MVVPRGQEHRAPQEVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCRVSFSFLDDSSEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEVRTFFASVSWRILELSRSHLRSSAQIH", "length": 613, "header": "tr|A0A8V0ZF71-1|A0A8V0ZF71_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "locus": { "chromosome": "7", "start_pos": 28525261, "end_pos": 28495733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050664.1", "url": "https://www.ensembl.org/id/ENSGALT00010050664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029911.1", "url": "https://www.ensembl.org/id/ENSGALP00010029911.1" } ] } }, { "isoform_ac": "A0A8V0ZF85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#A0A8V0ZF85-1", "sequence": { "sequence": "MVVPRGQEHRAPQEVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS", "length": 617, "header": "tr|A0A8V0ZF85-1|A0A8V0ZF85_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "locus": { "chromosome": "7", "start_pos": 28526866, "end_pos": 28495733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050681.1", "url": "https://www.ensembl.org/id/ENSGALT00010050681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029926.1", "url": "https://www.ensembl.org/id/ENSGALP00010029926.1" } ] } }, { "isoform_ac": "A0A8V0ZMK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#A0A8V0ZMK9-1", "sequence": { "sequence": "MVVPRGQEHRAPQEVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFHQAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS", "length": 600, "header": "tr|A0A8V0ZMK9-1|A0A8V0ZMK9_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "locus": { "chromosome": "7", "start_pos": 28526866, "end_pos": 28495733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050670.1", "url": "https://www.ensembl.org/id/ENSGALT00010050670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029915.1", "url": "https://www.ensembl.org/id/ENSGALP00010029915.1" } ] } }, { "isoform_ac": "A0A8V0ZML3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4/entry#A0A8V0ZML3-1", "sequence": { "sequence": "MVVPRGQEHRAPQEVETREDEEQNIKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDIDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVVQWLVKRAIETREEMGDYIRSYSISQFQKTHRLPEDDEFMQRKEKAIKTVTDIFEVYKPQRKYKRQKGAEEILDEESKVHATLLEYGRRYGFSRQAGKTEQTEDKKIVLPSGLAAAGKAEPCDEDDLRAAEELRIKTLMTGMAAMATEEGKLTASTVGQIVGLQSDEIKQIVSEYAEKQSELSAEERPERLGAAQQHRRKVASLNKQILQKTKLLEELQAKFVDLQAKCTEAKKTLTEVKSYSEKLDKELAALETIESQADSSVLQNLRMLVAMNENLKSQEQEFKAHCREEMERLQQDIENLKAEAAENGEEEEPNKLIDQQYQTEKEKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYSQVSATHKETKQFFTLYNTLDDKKVYLEKEVRKAMASSGSREQFLRQMEQIVEGIKQNRMKMEKKKQENKMRRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNEMLLSKLKASSS", "length": 607, "header": "tr|A0A8V0ZML3-1|A0A8V0ZML3_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 93 OS=Gallus gallus OX=9031 GN=CCDC93 PE=1 SV=1 CANONICAL=A0A8V0Z9H4-1" }, "locus": { "chromosome": "7", "start_pos": 28526866, "end_pos": 28495733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050675.1", "url": "https://www.ensembl.org/id/ENSGALT00010050675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029920.1", "url": "https://www.ensembl.org/id/ENSGALP00010029920.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424277", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATN9-1", "protein_name": "Coiled-coil domain-containing protein 93", "gene_name": "CCDC93", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLPKGPEGQDLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVIGGMTWCITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRAYSVSQFQKTYSLPEDDDFSKRKEKAIKTVIDLSDAYKPRRKYKRQQGAEELLDEESRVHATLLEYGRVTDSLMRYGFSRQNKTETAEDKKAALPMGLSAAEKADAHEEEELQAAEEQRIQSLMTKMMAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQILQKTKQLEELQASRTNLQAKYEEKKKTLTELKSYSEKLDQEQAALEKIEAKADPSILENLRALVAMNENLKSQEQEFKAHCREEMARLQQEIESLKAKRAPDGGEKDLSGGEPQGAPTPVMTHHEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEVLLSKVKAKAS", "length": 637 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1ZAC7-1", "protein_name": "Coiled-coil domain-containing protein 93", "gene_name": "fidipidine", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MANRDVFSKILPNVKLGTRYDEDGREVQVERREDSDATAKEQDTFDILVAAGYYRARIKGLSAFDKVVGGMTWCIECCDYDVDVDLLFHESLSIGQKIALVEKIVAVLIDMKCPHSLEPHQVQGLEFLAIHPVIQWLVKTSVENRAERGQRLKRFAIGQFHNHYQYKSDKDNLTKIRLASTNIKAIQDLYGPRRQYERQEAPDDDDDVSRVRLTLLEYGDPGPTFRSSAERKADRGPGEKDELDLEEYLRSLSLIKDDPTGTQKRIDLDPTARQELQQHYAEFKLEMETDAQELKSQNQQKRLEAAKIAMEHKIRRYCKENEQLQDAENEQKEKTKEVEDQLNTLNTELKAHKDTQDKADPKLLEKIQSLLQQHEELKKSEAEFKESCRTDLANLQLQIDDLESFSAQDAEAQAAALAGEEQRLKELRLQLAKRNRGIVAIERKLDAIPDRTELAQYQRRFHELHNEMSGKHLETKQYYTLYNTLNDKKRYMEKELALLNSICEAYNEGMMSPHGREDFIRQFESIVDGVKSAQDKVRHKYNEERMRRDELNEELQSLLELQRQYALAVKQLTRECQRCEQLQLQLRSIRGRTQS", "length": 595 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54CV3-1", "protein_name": "Coiled-coil domain-containing protein 93 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKRKSIFFANDSEDNTSSGDLSSFTKRGTITPGKIANAREGELSQMIDVESEQKYQEIIELLVTGGYFRARISGLSPFDKVVGGMAWSITASNVDVDADLFFQENSNIKQKVSLSEELIKALNRMKCPFPLQAQHITLLNYITLFPIIRWLITKVIETREETGDLLRMYSISMFSKDYIAPIDEDMKKSLNESCDFIESVEKRYKPTRKFKRANNTKSTPTQTLLEYGKLHRISRLPTNINENKEAAQKLESQLSGKDGSGKDTTEAEREEEEKRIKQMMKGMKGVEGDALSKVSGGVLKSFLPSEEITNLSERYGDMSDLGGAEGAKMMAEKLHRQKITNLEKLIQQKNQELEQIINAHSERQTELEQLQLLVGKKQAFNERIIRETEKLDALETPENTKALQALRSLVLLNETLIAQEELFKQSCKRQMVEYKQKIEQLLSQDASTQEDLQDSDRQQQIQQAFDSDIGKLKKLKLLLNKKNRDISLIQRYLDELPSRAELLQYQRQFVELSEQSSSKLTETRQYYTTYNTFEDKKTLLENELSILNSIQSKYSIAMSSTNNKELFIKSMDQIIDGIQQVLDKSENKWNVEKVRHDTLSDQYMTLLDQERNYYKLTKDFEEECRKNELLIKKLNELQ", "length": 639 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q567U6-1", "protein_name": "Coiled-coil domain-containing protein 93", "gene_name": "CCDC93", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS", "length": 631 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJT7-1", "protein_name": "Coiled-coil domain-containing protein 93", "gene_name": "Ccdc93", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIKRKDKAIQTVVDLSDAYKPRRKYRRQQGAEELLDEESRVHSTLLEYGRRHGFSRQSKTEKAEDKKTALAAGLSAAEKTDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYEGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKTKHLEELQANHTSLQAKYSDKKKTLTELKNHGEKLDQEQAALEKLEAKADPSILQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIEILKAERAPGEKTISSGEPQGALTSTMTHNEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKAKAS", "length": 629 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQK5-1", "protein_name": "Coiled-coil domain-containing protein 93", "gene_name": "Ccdc93", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIKRKDKAVKTVVGLSDAYKPRRKYRRQRGAEELPDEESRVHSTLLEYGRRYGFSRQSKTEKAEDKKTALAAGLSAAEKVDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKSKHLEELQANHTSLKAKYSDRKKTLTELKDHGEKLDKEQAALEKLEAKADPSMLQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGEKIISGGEPQGALTSTMTHNEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKAKAS", "length": 629 }, "evidence": [ { "id": "A0A8V0Z9H4", "url": "https://omabrowser.org/oma/group/A0A8V0Z9H4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" }, { "id": "PF21673", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21673" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC93 N-terminal", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 160, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9H4" }, { "id": "PF09762", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09762" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC93 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 643, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9I2-1", "uniprot_ac": "A0A8V0Z9I2", "uniprot_id": "A0A8V0Z9I2_CHICK", "mass": { "chemical_mass": 23815.0, "monoisotopic_mass": 23815.0 }, "refseq": {}, "gene_names": [ { "name": "DPCD", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2" } ] } ], "protein_names": [ { "name": "Protein DPCD", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPCD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2", "locus": { "chromosome": "6", "start_pos": 23590395, "end_pos": 23597879, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019139", "url": "https://www.ensembl.org/id/ENSGALG00010019139" } ] } } ], "crossref": [ { "id": "A0A8V0Z9I2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9I2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAB4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG87", "url": "https://www.orthodb.org/?gene=A0A8V0ZG87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31921:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31921:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPSWLERLRAASKTALVQDGKRKIHYQFEDGKEMAEEYDMKTGQLVSKWGGRRWREKNTLGGTGKWQVEVGDPTLPLLGPLESELIKESSSNPVFMRKDTLTSFQWRIRNLPYPKEVYSVSVEKEQRCCVIRTTNKKYYKKFPIPDLDRYQLPLDAAALSFTHTNNTLIITYQKPKEILAAEEELQKELKKIKAANSGDGDCKTQ", "length": 207, "header": "tr|A0A8V0Z9I2-1|A0A8V0Z9I2_CHICK Isoform 1 of Protein DPCD OS=Gallus gallus OX=9031 GN=DPCD PE=3 SV=1 CANONICAL=A0A8V0Z9I2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2/entry#A0A8V0Z9I2-1", "sequence": { "sequence": "MAVPSWLERLRAASKTALVQDGKRKIHYQFEDGKEMAEEYDMKTGQLVSKWGGRRWREKNTLGGTGKWQVEVGDPTLPLLGPLESELIKESSSNPVFMRKDTLTSFQWRIRNLPYPKEVYSVSVEKEQRCCVIRTTNKKYYKKFPIPDLDRYQLPLDAAALSFTHTNNTLIITYQKPKEILAAEEELQKELKKIKAANSGDGDCKTQ", "length": 207, "header": "tr|A0A8V0Z9I2-1|A0A8V0Z9I2_CHICK Isoform 1 of Protein DPCD OS=Gallus gallus OX=9031 GN=DPCD PE=3 SV=1 CANONICAL=A0A8V0Z9I2-1" }, "locus": { "chromosome": "6", "start_pos": 23597837, "end_pos": 23590501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046334.1", "url": "https://www.ensembl.org/id/ENSGALT00010046334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027597.1", "url": "https://www.ensembl.org/id/ENSGALP00010027597.1" } ] } }, { "isoform_ac": "A0A8V0ZAB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2/entry#A0A8V0ZAB4-1", "sequence": { "sequence": "MPSPSLPPGPFWGGPEGRERGLGPRAETGCKRRDTALCCCPRTRKRGLERGDTVPDKGTGPYTQGYAYSYCLSAPALLLGKRKIHYQFEDGKEMAEEYDMKTGQLVSRRWREKNTLGGTGKWQVEVGDPTLPLLGPLESELIKESSSNPVFMRKDTLTSFQWRIRNLPYPKEVYSVSVEKEQRCCVIRTTNKKYYKKFPIPDLDRYQLPLDAAALSFTHTNNTLIITYQKPKEILAAEEELQKELKKIKAANSGDGDCKTQ", "length": 261, "header": "tr|A0A8V0ZAB4-1|A0A8V0ZAB4_CHICK Computationally mapped isoform of Protein DPCD OS=Gallus gallus OX=9031 GN=DPCD PE=3 SV=1 CANONICAL=A0A8V0Z9I2-1" }, "locus": { "chromosome": "6", "start_pos": 23597743, "end_pos": 23590501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046319.1", "url": "https://www.ensembl.org/id/ENSGALT00010046319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027586.1", "url": "https://www.ensembl.org/id/ENSGALP00010027586.1" } ] } }, { "isoform_ac": "A0A8V0ZG87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I2/entry#A0A8V0ZG87-1", "sequence": { "sequence": "MAVPSWLERLRAASKTALVQDGKRKIHYQFEDGKEMAEEYDMKTGQLVSRRWREKNTLGGTGKWQVEVGDPTLPLLGPLESELIKESSSNPVFMRKDTLTSFQWRIRNLPYPKEVYSVSVEKEQRCCVIRTTNKNSDNTERFEPCGNKLRTFLPLHQESHLPFVAVFTVTWKINCNWDRVAREAKPHMQPDEWRTPCGMTATAACSCSSL", "length": 210, "header": "tr|A0A8V0ZG87-1|A0A8V0ZG87_CHICK Computationally mapped isoform of Protein DPCD OS=Gallus gallus OX=9031 GN=DPCD PE=3 SV=1 CANONICAL=A0A8V0Z9I2-1" }, "locus": { "chromosome": "6", "start_pos": 23597837, "end_pos": 23592976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046306.1", "url": "https://www.ensembl.org/id/ENSGALT00010046306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027579.1", "url": "https://www.ensembl.org/id/ENSGALP00010027579.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAB7-1", "uniprot_ac": "A0A8V0ZAB7", "uniprot_id": "A0A8V0ZAB7_CHICK", "mass": { "chemical_mass": 71081.0, "monoisotopic_mass": 71081.0 }, "refseq": { "ac": "XP_040518595", "name": "late secretory pathway protein AVL9 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518595" }, "gene_names": [ { "name": "AVL9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" } ] }, { "name": "AVL9", "type": "synonym", "evidence": [ { "id": "XP_040518595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518595" } ] } ], "protein_names": [ { "name": "AVL9 cell migration associated", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7/entry#names_and_taxonomy" } ] }, { "name": "late secretory pathway protein AVL9 homolog", "type": "synonym", "evidence": [ { "id": "XP_040518595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518595" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518595" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AVL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7", "locus": { "chromosome": "2", "start_pos": 47993097, "end_pos": 48029623, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019356", "url": "https://www.ensembl.org/id/ENSGALG00010019356" } ] } } ], "crossref": [ { "id": "A0A8V0ZAB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "420750", "url": "https://www.ncbi.nlm.nih.gov/gene/420750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420750", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRTQFRV", "url": "https://omabrowser.org/oma/group/IRTQFRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9K6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAB7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH04", "url": "https://www.orthodb.org/?gene=A0A8V0ZH04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31017:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31017:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040518595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518595", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKRGAPPAAPPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGEGHDSHNLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRCGDRTTVYGVSCYRQIEAKALKVRQADITRETVQKSVCVLSQLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYDHMNSSLGGTLLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLTDSSHYRPRKSVSEDAGLQETTPWLDNSTSVSAGGISNTNLGTGKGGKKMAGNHSVEGQKANIPFCQSEKTYNGAQSSNGTVQHLEVPSRTSPESSESDWETLDPSILEESSMKGECEKAALEQVENRPSECPSSESLPITVQPQANTGHMVLVPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEIEDAHVQIHDPELRKILNPTTADLRFADYLVKHVTENRDDVFLDGTGWEGGDEWIRAQFSAYLHALLASVLQPDNEKTLSDFGTAFVAAWKNTHNYRVWNSNKHPALAEVHSSHPFQGQYSVSDVKLRLSHSVQNSERGKKIGNVMVSTSRNVVQTGKAVGQSVGGAFTSAKSAMSSWFSTFTQSSQSLGD", "length": 644, "header": "tr|A0A8V0ZAB7-1|A0A8V0ZAB7_CHICK Isoform 1 of AVL9 cell migration associated OS=Gallus gallus OX=9031 GN=AVL9 PE=1 SV=1 CANONICAL=A0A8V0ZAB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7/entry#A0A8V0Z9K6-1", "sequence": { "sequence": "MEKRGAPPAAPPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGEGHDSHNLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRCGDRTTVYGVSCYRQIEAKALKVRQADITRETVQKSVCVLSQLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYDHMNSSLGGTLLEGSQVYLGLSPRDLVLHFRHKVLFYISPVNRLVGALMTVLSLFPGMIEHGLTDSSHYRPRKSVSEDAGLQETTPWLDNSTSVSAGGISNTNLGTGKGGKKMAGNHSVEGQKANIPFCQSEKTYNGAQSSNGTVQHLEVPSRTSPESSESDWETLDPSILEESSMKGECEKAALEQVENRPSECPSSESLPITVQPQANTGHMVLVPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEIEDAHVQIHDPELRKILNPTTADLRFADYLVKHVTENRDDVFLDGTGWEGGDEWIRAQFSAYLHALLASVLQPDNEKTLSDFGTAFVAAWKNTHNYRVWNSNKHPALAEVHSSHPFQGQYSVSDVKLRLSHSVQNSERGKKIGNVMVSTSRNVVQTGKAVGQSVGGAFTSAKSAMSSWFSTFTQSSQSLGD", "length": 631, "header": "tr|A0A8V0Z9K6-1|A0A8V0ZAB7_CHICK Computationally mapped isoform of AVL9 cell migration associated OS=Gallus gallus OX=9031 GN=AVL9 PE=1 SV=1 CANONICAL=A0A8V0ZAB7-1" }, "locus": { "chromosome": "2", "start_pos": 48029499, "end_pos": 47994552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046816.1", "url": "https://www.ensembl.org/id/ENSGALT00010046816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027868.1", "url": "https://www.ensembl.org/id/ENSGALP00010027868.1" } ] } }, { "isoform_ac": "A0A8V0ZAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7/entry#A0A8V0ZAB7-1", "sequence": { "sequence": "MEKRGAPPAAPPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGEGHDSHNLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRCGDRTTVYGVSCYRQIEAKALKVRQADITRETVQKSVCVLSQLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYDHMNSSLGGTLLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLTDSSHYRPRKSVSEDAGLQETTPWLDNSTSVSAGGISNTNLGTGKGGKKMAGNHSVEGQKANIPFCQSEKTYNGAQSSNGTVQHLEVPSRTSPESSESDWETLDPSILEESSMKGECEKAALEQVENRPSECPSSESLPITVQPQANTGHMVLVPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEIEDAHVQIHDPELRKILNPTTADLRFADYLVKHVTENRDDVFLDGTGWEGGDEWIRAQFSAYLHALLASVLQPDNEKTLSDFGTAFVAAWKNTHNYRVWNSNKHPALAEVHSSHPFQGQYSVSDVKLRLSHSVQNSERGKKIGNVMVSTSRNVVQTGKAVGQSVGGAFTSAKSAMSSWFSTFTQSSQSLGD", "length": 644, "header": "tr|A0A8V0ZAB7-1|A0A8V0ZAB7_CHICK Isoform 1 of AVL9 cell migration associated OS=Gallus gallus OX=9031 GN=AVL9 PE=1 SV=1 CANONICAL=A0A8V0ZAB7-1" }, "locus": { "chromosome": "2", "start_pos": 48029499, "end_pos": 47994552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046819.1", "url": "https://www.ensembl.org/id/ENSGALT00010046819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027870.1", "url": "https://www.ensembl.org/id/ENSGALP00010027870.1" } ] } }, { "isoform_ac": "A0A8V0ZH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7/entry#A0A8V0ZH04-1", "sequence": { "sequence": "MEQAAQGSGHSPRLLEIKVEFSYPPLIPGEGHDSHNLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRCGDRTTVYGVSCYRQIEAKALKVRQADITRETVQKSVCVLSQLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYDHMNSSLGGTLLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLTDSSHYRPRKSVSEDAGLQETTPWLDNSTSVSAGGISNTNLGTGKGGKKMAGNHSVEGQKANIPFCQSEKTYNGAQSSNGTVQHLEVPSRTSPESSESDWETLDPSILEESSMKGECEKAALEQVENRPSECPSSESLPITVQPQANTGHMVLVPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEIEDAHVQIHDPELRKILNPTTADLRFADYLVKHVTENRDDVFLDGTGWEGGDEWIRAQFSAYLHALLASVLQPDNEKTLSDFGTAFVAAWKNTHNYRVWNSNKHPALAEVHSSHPFQGQYSVSDVKLRLSHSVQNSERGKKIGNVMVSTSRNVVQTGKAVGQSVGGAFTSAKSAMSSWFSTFTQSSQSLGD", "length": 631, "header": "tr|A0A8V0ZH04-1|A0A8V0ZH04_CHICK Computationally mapped isoform of AVL9 cell migration associated OS=Gallus gallus OX=9031 GN=AVL9 PE=1 SV=1 CANONICAL=A0A8V0ZAB7-1" }, "locus": { "chromosome": "2", "start_pos": 48019163, "end_pos": 47994552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046814.1", "url": "https://www.ensembl.org/id/ENSGALT00010046814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027867.1", "url": "https://www.ensembl.org/id/ENSGALP00010027867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420750", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IRC7-1", "protein_name": "Late secretory pathway protein AVL9 homolog isoform 2", "gene_name": "avl9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MECQSKEEPVLHIVVVGFHHKKGCQVEFSYPPIIPSAGHDSSTLPEEWKYLPFLALPDGAHNHQEDTVYFHLPPLDGQLKCVYGVSCYRQMEAKALKKREADVTRETVQKSVCVLSRLPLFGLIQAKLQLITHAYFEEKDFSQISILKELYDHMNRSLNCTSLEGSQIYLSLSARDLILHFKHKVLVLFKLILLEKKILFYVTPVKRLVETLMTILSLFPGMIEYGLADSSHYQTRRSISEDFSSPEIISADEESLSLFSTDITRTPKENEHRYDVNDPPDQSKPCNSTLDTHYIDARAEQQNLLDSSESEWETLEPHVMDEKESKMDIGHLEMFDADSGLPITVQPQSATGHGTLSTGLVSGLQEDQYGQPLAIFTKGYLCMPYMALQQHHLLSDINVRGFVSGATNVLFRQQRHLSDAVVDVDEAQILIHDPELRKMLNLSTADLRFADYLVKHVTENKEDVFLDGTGWEGGDEWIRAQFGLYMHSLLSSALQQDHERLLADYGVLFTSAWKMTHNYKMWISNKHPAMAEITPGHPFQGQYSVADVKIRLSHSMQNSERGKKIGNAVMSTSRSVVQTGKAVGQSVGGALTVAKSAMSSWFSMLAQPTAAVTSSQQSSD", "length": 620 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I5ZNY0-1", "protein_name": "AVL9 cell migration associated", "gene_name": "Avl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKAGRESDGAPCGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHAVPEEWKYLPSLALPDGAHNYQEDTVFFHLPPRNGNGATVYGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGASLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLSDCSQYRPRKSMSEDAGLQEGNPSADDFISESTSDNLNTSLGIVTRIVAVNHGEDAVPPTEKPYFQVEGNNNKGQEHSDTGRYLELPPRPSPESSESDWETLDPSVLEDASLKEREQMGSDQTHLFQKDSVPSDSPPITVQPQANTRQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKMLSDYGTTFVAAWKNTHNYRVWNSNKHPALAEINPNHPFQGQYSVSDMKLRFSHSVQNSERGKKIGNVMVTTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTTSTPQSLPEPPNGKP", "length": 649 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TD12-1", "protein_name": "AVL9 cell migration associated", "gene_name": "AVL9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEIRRGGDGPPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHTLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRNGNGATIYGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGTSLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNKLVGALMTVLSLFPGMIEHGLSDSSQYRPRKSMSEDAGLQESNPPADEFVSVPASDISNTNLGTVKKILGNHGGDAAIKTEEPLFQVEDDSSEQEASDSNQYLKPPSRPSPESSESDWETLDPTVLEDSSLKEREQVGSEQTNSFPKDSLPSDSPPITVQPQANTGQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTIRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKILSDYGTTFVTAWKNTHNYRVWNSNKHPALAEINPNSVQNSERGKKLGNVMVTTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTSSTPQSLTELPDGKP", "length": 628 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HMP7-1", "protein_name": "Late secretory pathway protein AVL9 homolog isoform X1", "gene_name": "Avl9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKAGREGDGAPCGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHALPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRNGNGATVYGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGASLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLSDCSQYRPRKSMSEDIGLQQSNPPADDFISESTSDISNTNLGTVTKIISGNHGGDTVLQLEKPCFQVEDNNNKEQEPSDTGRYLKLPPRPSPESSESDWETLDPSVLEDSSLKEREQMESDQTNIFQKDSVPSDSPPITVQPQANTRQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKMLSDYGTTFVAAWKNTHNYRVWNSNKHPALSEINPNHPFQGQYSVSDMKLRFSHSVQNSERGKKIGNVMVSTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTTSTPQSLPEPPNGKP", "length": 649 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12500-1", "protein_name": "Late secretory pathway protein AVL9", "gene_name": "AVL9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDEHEEAVIFGICLVDFHHKRGPEIEYWYGLPEGTQSAELWPNLPFQALPDGSHSFEETFTYFTLLYDERRQRSPPNGATDLSDDSINDNTTLFAISCSRQIKSDELVTKDKDVTRSTVQKAIVVISRQPIFGQIKDKLSIVTNAFFLQHDFGDRKIIQSLYENLKSIYTPASLVRNAENRLYIGLCLRKILHDFKRNALVLLKAIMLEKKIIVYGNDVEALCNLQFGLISLIPDLMSNLQDSGSPQLFQDISKLNVVDSFKSSNRESVLRFLGFPLPIFEKGGLFSPYTPLQQMNDIRSERTLFFMIGSSNTLLAEQKEELCHIFVNTDNSTVDILDKTLNPVLQLSSHDKKWIESISGIVSDTWNENDDETPKNSQFEGSEDFIRWQFEDYLTGLLSSVKLSDYLDLHKENDQALKTIPEDMLNSNPVHLFNLNWVQSWKETQNFLIFNSRTDDRLFDLFPPKHIYNGADTLSLLQQRFLATFHNLKRSSSNSSSNKNGHQSEEDIKDQESIESKKSVSQISVNPGKNTDKPAANLWNSWKEYFNKPKNTANEDVTESTEDLKNRSKTSNAIQKAMMGLGLHYKPDAETDQQSEEVGNSEDNEDDDTDEDSEDDDDDGGDDDDSEDDDDDDDGEGDENGDDGEGDENGDDGEGDENGDKEDSQDFSNGFTDVTNINTDHDKENEQNFEGNAENFNEDETVADKDIEGGPESNKNSDSKTDIYENDRNVEDSSKTRNTVKKSNEEGGANDAAIGNCVQDEEKL", "length": 764 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54NJ9-1", "protein_name": "UDENN domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSINLIEYIGVIGFHHSLGHRIEFLYPDLDEESKKQYNWNLLPFYGIADGVHNSFEDYTFFIMEEINPTTSPSKKLYGLSYFKQKNKRDLPKQAITPEDTRSSIQKSVVILSKFPIFNSFKTQLSSATICYFNQGDFQNTDLLVTWFHAQNNEFKERNNEKLVINNSFGYQMNQVLENNNNNNKKLIPINSDFLFGSMSLKKLIMHFGRNSLVFFKLIMLERGVVVFCPQPVSPVSEAIMSVLSLHSKSYDLLFSTNQSISNDFQIDWTTSTSEEMVLNQLGLPIPLFNDGKDNNTTNSDGEKVYGSGGMILQPYLPLQQISLLLPPQQGSGKTFNGFLVGTSNSLFLKNPPSTVHAIVDIQNGEIQFKDESLNRIMELTSSDRRFIDNIYDKVELYNRNNSNNNNNNNNNNNNNNNNGNNSDNDNAVYKEGCDKWIRDQFENYIVCLLSSICRFIKIEDGKNVLTNMDQLAQYNDSWIRRWTTTKNFYLWKKQMFQNLPLPQLNYPVHPSGPPSDMLDRFQDKLTTSIKDLQPLTNQFSQLFSFTSTFLRNQINNNNNNSSNNNNNNFDNIDDNGEQQKQQIYNTHILKSSYSQEFYSSGDDINSTNTTWSKVQENGIIAATKAVSAVKPLVSSSKTMARQFSNQLMNYIAPHPSLDIPQLNQNDQDNSIFESQANEYDFIGNYYSNNNNNNHNNNNNNSNNNNDDDNYNNNNNNNNNTNSNNNNNNSNDNNGTYTIAPITTTSTTTKSSSTKIVGIISTSNDDNNDESINGISNEKKSYQLPSDTRDDAYEL", "length": 794 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q80U56-1", "protein_name": "Late secretory pathway protein AVL9 homolog", "gene_name": "Avl9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKSGRESDGAPCGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHTLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRNGNGATVYGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGASLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNRLVGALMTVLSLFPGMIEHGLSDCSQYRPRKSMSEDAGPQESNPSADDFTSESTSDVLNTSLETVTRVMAVNHGEDAVPKTEKPYFQVEGNNNKGQEPSDSGRYLELPPRPSPESSESDWETLDPSVLEDASLKEREQMGSDQTHLFQKDSLPSDSPPITVQPQANNRQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKMLSDYGTTFVAAWKNTHNYRVWNSNKHPALSEINPNHPFQGQYSVSDMKLRFSHSVQNSERGKKIGSVMVTTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTTSTPQSLPEPPNGKP", "length": 649 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBF6-1", "protein_name": "Late secretory pathway protein AVL9 homolog", "gene_name": "AVL9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKARRGGDGVPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHTLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRNGNGATVFGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGASLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNKLVGALMTVLSLFPGMIEHGLSDCSQYRPRKSMSEDGGLQESNPCADDFVSASTADVSHTNLGTIRKVMAGNHGEDAAMKTEEPLFQVEDSSKGQEPNDTNQYLKPPSRPSPDSSESDWETLDPSVLEDPNLKEREQLGSDQTNLFPKDSVPSESLPITVQPQANTGQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKILSDYGTTFVTAWKNTHNYRVWNSNKHPALAEINPNHPFQGQYSVSDMKLRFSHSVQNSERGKKIGNVMVTTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTTSTSQSLTEPPDEKP", "length": 648 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VYB2-1", "protein_name": "UDENN domain-containing protein", "gene_name": "Dmel\\CG11178", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASEPENKPPILHILVVGFHHKLGCQVEFSHPPLISGSTGRNECPSGWKYLPTLALPDGSHNFAEDTVFFNLPSLYEPAESIYGVSCYRQIRVEKLKIRTADLTRSTVQKSVCILARLPIYGYIEVKLALIADAFFDQGDFSGTELLAKAYQQLNACLQDDESRRPLRHFHVGLSLREIVLHWRHKTLMLFKLMLLQRRVVCFGSPVRQMCVLILGMASLVPRLLEKGFQEVACVRTSRPLSPMPDFTDSLQREAQAEAEAELEAVASVAAATDEQKLTPESATAVEGEAEELALVSSAASAGEEQVSGDDTSTRSTPNSQSQDSSNGRNSSLTREASVDTLASNLAALCAVNPDEYRAPVSIFASGNLCLPYLSLPYMDLLSDPMVLSYVIGTSNVLFQQKRQLADVLVDIEAANLDAHDPELRRQLVLSTEDLRYMDYIMKHVQSPKEDAEGSEYWIREQFQGYILALLRTAVAPDATPKDNDHFNAHFMGAFKRTQCFQEWYDVRPEPEFFEALPAGHPFAGTLSVADMKLKLAQTMQNSESGRKINQAVNTTSRAVGGAISQAKGAFSSWWSSITTAPPNATNAGPATSSSNGQEGDVSEGAAAQEISVTFQNHKDVEDLDVAGVSIHLAGQEEAHESHESQSVSCDKPQGIVEIGREAELLDKTAQSEEPKIAAASQAGRPGCGGDVATSAVERSSGDVFIV", "length": 707 }, "evidence": [ { "id": "A0A8V0ZAB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAB7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB7" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 562, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 312, "end_pos": 314 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9K7-1", "uniprot_ac": "A0A8V0Z9K7", "uniprot_id": "A0A8V0Z9K7_CHICK", "mass": { "chemical_mass": 55819.0, "monoisotopic_mass": 55819.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Mab-21-like HhH/H2TH-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9K7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LSHLLQIMALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQLEQEDEEEEYFHHSALTRYIARRAWKKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 483, "header": "tr|A0A8V0Z9K7-1|A0A8V0Z9K7_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z9K7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7/entry#A0A8V0Z9K7-1", "sequence": { "sequence": "LSHLLQIMALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQLEQEDEEEEYFHHSALTRYIARRAWKKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 483, "header": "tr|A0A8V0Z9K7-1|A0A8V0Z9K7_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z9K7-1" }, "locus": { "chromosome": "5", "start_pos": 56442148, "end_pos": 56440501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045837.1", "url": "https://www.ensembl.org/id/ENSGALT00010045837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027318.1", "url": "https://www.ensembl.org/id/ENSGALP00010027318.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9K7" }, { "id": "PF20266", "database": "Pfam", "url": 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421155.4. 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9L4-1", "uniprot_ac": "A0A8V0Z9L4", "uniprot_id": "A0A8V0Z9L4_CHICK", "mass": { "chemical_mass": 135130.0, "monoisotopic_mass": 135130.0 }, "refseq": {}, "gene_names": [ { "name": "KCNH7", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily H member 7", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4", "locus": { "chromosome": "7", "start_pos": 20660555, "end_pos": 20455399, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020992", "url": "https://www.ensembl.org/id/ENSGALG00010020992" } ] } } ], "crossref": [ { "id": "A0A8V0Z9L4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9L4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424184", "url": "https://www.ncbi.nlm.nih.gov/gene/424184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9L4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFC2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGJ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZGJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZGQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMR4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10217", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10217", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10217:SF466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10217:SF466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHHIAQIAQALLGSEERKVEVTYYHKDGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENISSPEKCNPILPSKLVNRKLFGFRLPGLRLLTYRKQSLPQEDPDAVIIDSSKHSDDSVAMKHFKSPTKESCSPSEVDDTKALIQPSEGSPLVNISGPLDHSSPKQQWDRLYPDMIQTSNPLTHSRSKESICSIRRASSVHDIEGFNVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDIKNEKKSSSPPSSEKAIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDSEERKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSEETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLAHKIGWLDSLGEQLGKHYNKSDASSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQNLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFVSRGSIEILKSDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDLFLTNLELTFNLRDETAKSDIIIRSQTTNDTNGDNCKLRRRKLSFQSEREKDYFKENDQSDPEPTGDNSRYYQSIKKHFEEKKSGSSSFVSSIEDEQKPLFSGVADYPSVTEKTTELDLEEMIHATEEILTDKRTDSCKDITDKRNWEEQNMREYQDSPSHSALPHVTWGICDTESDYVYGEVENRLDLLQEQLNRLESQMTADIQTILQILQRQSTLIPPAYSMVTAGAEYQQPAIRFTQKLHPVASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLASFLDQERDQSAESPPQHPKPYLPSIRHPSLPECSVSTVGILSLHRHVSDPGLPGK", "length": 1194, "header": "tr|A0A8V0Z9L4-1|A0A8V0Z9L4_CHICK Isoform 1 of Potassium voltage-gated channel subfamily H member 7 OS=Gallus gallus OX=9031 GN=KCNH7 PE=4 SV=1 CANONICAL=A0A8V0Z9L4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4/entry#A0A8V0Z9L4-1", "sequence": { "sequence": "MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHHIAQIAQALLGSEERKVEVTYYHKDGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENISSPEKCNPILPSKLVNRKLFGFRLPGLRLLTYRKQSLPQEDPDAVIIDSSKHSDDSVAMKHFKSPTKESCSPSEVDDTKALIQPSEGSPLVNISGPLDHSSPKQQWDRLYPDMIQTSNPLTHSRSKESICSIRRASSVHDIEGFNVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDIKNEKKSSSPPSSEKAIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDSEERKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSEETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLAHKIGWLDSLGEQLGKHYNKSDASSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQNLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFVSRGSIEILKSDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDLFLTNLELTFNLRDETAKSDIIIRSQTTNDTNGDNCKLRRRKLSFQSEREKDYFKENDQSDPEPTGDNSRYYQSIKKHFEEKKSGSSSFVSSIEDEQKPLFSGVADYPSVTEKTTELDLEEMIHATEEILTDKRTDSCKDITDKRNWEEQNMREYQDSPSHSALPHVTWGICDTESDYVYGEVENRLDLLQEQLNRLESQMTADIQTILQILQRQSTLIPPAYSMVTAGAEYQQPAIRFTQKLHPVASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLASFLDQERDQSAESPPQHPKPYLPSIRHPSLPECSVSTVGILSLHRHVSDPGLPGK", "length": 1194, "header": "tr|A0A8V0Z9L4-1|A0A8V0Z9L4_CHICK Isoform 1 of Potassium voltage-gated channel subfamily H member 7 OS=Gallus gallus OX=9031 GN=KCNH7 PE=4 SV=1 CANONICAL=A0A8V0Z9L4-1" }, "locus": { "chromosome": "7", "start_pos": 20659551, "end_pos": 20455637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050751.1", "url": "https://www.ensembl.org/id/ENSGALT00010050751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029967.1", "url": "https://www.ensembl.org/id/ENSGALP00010029967.1" } ] } }, { "isoform_ac": "A0A8V0ZFC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4/entry#A0A8V0ZFC2-1", "sequence": { "sequence": "MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHHIAQIAQALLGSEERKVEVTYYHKDGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENISSPEKCNPILPSKLVNHGNNLSSGSSSGKLFGFRLPGLRLLTYRKQSLPQEDPDAVIIDSSKHSDDSVAMKHFKSPTKESCSPSEVDDTKALIQPSEGSPLVNISGPLDHSSPKQQWDRLYPDMIQTSNPLTHSRSKESICSIRRASSVHDIEGFNVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDIKNEKKSSSPPSSEKAIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDSEERKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSEETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLAHKIGWLDSLGEQLGKHYNKSDASSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQNLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFVSRGSIEILKSDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDLFLTNLELTFNLRDETAKSDIIIRSQTTNDTNGDNCKLRRRKLSFQSEREKDYFKENDQSDPEPTGDNSRYYQSIKKHFEEKKSGSSSFVSSIEDEQKPLFSGVADYPSVTEKTTELDLEEMIHATEEILTDKRTDSCKDITDKRNWEEQNMREYQDSPSHSALPHVTWGICDTESDYVYGEVENRLDLLQEQLNRLESQMTADIQTILQILQRQSTLIPPAYSMVTAGAEYQQPAIRFTQKLHPVASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLASFLDQERDQSAESPPQHPKPYLPSIRHPSLPECSVSTVGILSLHRHVSDPGLPGK", "length": 1212, "header": "tr|A0A8V0ZFC2-1|A0A8V0ZFC2_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily H member 7 OS=Gallus gallus OX=9031 GN=KCNH7 PE=4 SV=1 CANONICAL=A0A8V0Z9L4-1" }, "locus": { "chromosome": "7", "start_pos": 20659551, "end_pos": 20455637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050746.1", "url": "https://www.ensembl.org/id/ENSGALT00010050746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029964.1", "url": "https://www.ensembl.org/id/ENSGALP00010029964.1" } ] } }, { "isoform_ac": "A0A8V0ZGJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4/entry#A0A8V0ZGJ9-1", "sequence": { "sequence": "MPLFHIESHAFMSEFICFVSLQEWLMHTGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENISSPEKCNPILPSKLVNHGNNLSSGSSSGKLFGFRLPGLRLLTYRKQSLPQEDPDAVIIDSSKHSDDSVAMKHFKSPTKESCSPSEVDDTKALIQPSEGSPLVNISGPLDHSSPKQQWDRLYPDMIQTSNPLTHSRSKESICSIRRASSVHDIEGFNVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDIKNEKKSSSPPSSEKAIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDSEERKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSEETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLAHKIGWLDSLGEQLGKHYNKSDASSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQNLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFVSRGSIEILKSDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDLFLTNLELTFNLRDETAKSDIIIRSQTTNDTNGDNCKLRRRKLSFQSEREKDYFKENDQSDPEPTGDNSRYYQSIKKHFEEKKSGSSSFVSSIEDEQKPLFSGVADYPSVTEKTTELDLEEMIHATEEILTDKRTDSCKDITDKRNWEEQNMREYQDSPSHSALPHVTWGICDTESDYVYGEVENRLDLLQEQLNRLESQMTADIQTILQILQRQSTLIPPAYSMVTAGAEYQQPAIRFTQKLHPVASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLASFLDQERDQSAESPPQHPKPYLPSIRHPSLPECSVSTVGILSLHRHVSDPGLPGK", "length": 1131, "header": "tr|A0A8V0ZGJ9-1|A0A8V0ZGJ9_CHICK Computationally mapped isoform of Potassium voltage-gated channel subfamily H member 7 OS=Gallus gallus OX=9031 GN=KCNH7 PE=4 SV=1 CANONICAL=A0A8V0Z9L4-1" }, "locus": { "chromosome": "7", "start_pos": 20659551, "end_pos": 20549081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050740.1", "url": "https://www.ensembl.org/id/ENSGALT00010050740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029961.1", "url": "https://www.ensembl.org/id/ENSGALP00010029961.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L4/entry#A0A8V0ZGQ5-1", "sequence": { "sequence": "MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHHIAQIAQALLGSEERKVEVTYYHKDGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENISSPEKCNPILPSKLVNHGNNLSSGSSSGKLFGFRLPGLRLLTYRKQSLPQEDPDAVIIDSSKHSDDSVAMKHFKSPTKESCSPSEVDDTKALIQPSEGSPLVNISGPLDHSSPKQQWDRLYPDMIQTSNPLTHSRSKESICSIRRASSVHDIEGFNVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDIKNEKKSSSPPSSEKAIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDSEERKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSEETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLAHKIGWLDSLGEQLGKHYNKSDASSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQNLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFVSRGSIEILKSDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDLFLTNLELTFNLRDETAKSDIIIRSQTTNDTNGDNCKLRRRKLSFQSEREKDYFKENDQSDPEPTGDNSRYYQSIKKHFEEKKSGSSSFVSSIEDEQKPLFSGVADYPSVTEKTTELDLEEMIHATEEILTDKRTDSCKDITDKRNWEEQNMREYQDSPSHSALPHVTWGICDTESDYVYGEVENRLDLLQEQLNRLESQMTADIQTILQILQRQSTLIPPAYSMVTAGAEYQQPAIRFTQKLHPVASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLASFLDQERDQSAESPPQHPKPYLPSIRHPSLPECSVSTVGILSLHRHVSDPGLPGK", 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Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9M3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYHWTRIHCKLEFLSKERLSETITASHRSAAGAQPGLPTSPTPGRPTAAQPGPSPARGPIPAAGPPWPGPGGRAGPSRGTRGGSRSIRRRGGRRRRGRPAARGRRTAPAPSPGLRLIISKASQRIPMSSRPVSAREYESSDQFPGHSASPPVPNSSETEGLIFYHMDLYGSNERFDIFPEEPSGQGSRFLGNTRRESALSSEKCQNSHEAGYDMEKEVAELAKMYGLDEDREKELELLGGHLETVGSKWLPAHTQKSGLQDSVYNRSKSSSPVKDQSKSTKHQELPDEVSQDEDQHKARTENEADSHTWFREGLSSSGVSDERSSQAVSEEEEMADVFCCTCKIPIRAFDKLFGEHKDHEVAQLSSAVESEKEEIHKNMCKLEEQIAQVENFASHLEEIFITVEENFGRQEQNFEVHYNDAVQVLAQKYEEQLEALGEEKKQKLEALYEQLVSCGEHLDTCKELMDTTHKLYQENDKVTFMKEAVTMVDRLEKFLKKEVNLKLSTHPDFEERAIDFSEVEQLMNSINTIPAPCAPVINPQAPNAATGTSLRVCWGLFSDDTVECYQLCYKPVSNERHSDEQAEHMLKVKETYCTISNLLPNTQYEFWVSASNASGISPPSERAVYVTAPSPPIIKSKKIRSCENAALVCWESRDVNPVDSYTVELSKLTDEENGDIITESIVGIPNCEALIHLQPAQSYHICVKALNLGGSSERSEPVLIHTTGTYFCLNEDTAHPLLAILDDGFTIACDELENPECDLPVYDNSFTRCIGILGSLIPFPGKHYWEVEAEEDTEYRIGVAFENTPRHGYLGANNSSWCMRHIITPSRHKYEFLHSGMTPDIRITVPPTKIGILLDYESYRLSFYNADIAQHLYTFNSHFQHYVHPCFALETPGTLKVHTGITVPPWTALL", "length": 910, "header": "tr|A0A8V0Z9M3-1|A0A8V0Z9M3_CHICK Isoform 1 of Fibronectin type III and SPRY domain containing 2 OS=Gallus gallus OX=9031 GN=FSD2 PE=4 SV=1 CANONICAL=A0A8V0Z9M3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M3/entry#A0A8V0Z9M3-1", "sequence": { "sequence": "MYHWTRIHCKLEFLSKERLSETITASHRSAAGAQPGLPTSPTPGRPTAAQPGPSPARGPIPAAGPPWPGPGGRAGPSRGTRGGSRSIRRRGGRRRRGRPAARGRRTAPAPSPGLRLIISKASQRIPMSSRPVSAREYESSDQFPGHSASPPVPNSSETEGLIFYHMDLYGSNERFDIFPEEPSGQGSRFLGNTRRESALSSEKCQNSHEAGYDMEKEVAELAKMYGLDEDREKELELLGGHLETVGSKWLPAHTQKSGLQDSVYNRSKSSSPVKDQSKSTKHQELPDEVSQDEDQHKARTENEADSHTWFREGLSSSGVSDERSSQAVSEEEEMADVFCCTCKIPIRAFDKLFGEHKDHEVAQLSSAVESEKEEIHKNMCKLEEQIAQVENFASHLEEIFITVEENFGRQEQNFEVHYNDAVQVLAQKYEEQLEALGEEKKQKLEALYEQLVSCGEHLDTCKELMDTTHKLYQENDKVTFMKEAVTMVDRLEKFLKKEVNLKLSTHPDFEERAIDFSEVEQLMNSINTIPAPCAPVINPQAPNAATGTSLRVCWGLFSDDTVECYQLCYKPVSNERHSDEQAEHMLKVKETYCTISNLLPNTQYEFWVSASNASGISPPSERAVYVTAPSPPIIKSKKIRSCENAALVCWESRDVNPVDSYTVELSKLTDEENGDIITESIVGIPNCEALIHLQPAQSYHICVKALNLGGSSERSEPVLIHTTGTYFCLNEDTAHPLLAILDDGFTIACDELENPECDLPVYDNSFTRCIGILGSLIPFPGKHYWEVEAEEDTEYRIGVAFENTPRHGYLGANNSSWCMRHIITPSRHKYEFLHSGMTPDIRITVPPTKIGILLDYESYRLSFYNADIAQHLYTFNSHFQHYVHPCFALETPGTLKVHTGITVPPWTALL", "length": 910, "header": "tr|A0A8V0Z9M3-1|A0A8V0Z9M3_CHICK Isoform 1 of Fibronectin type III and SPRY domain containing 2 OS=Gallus gallus OX=9031 GN=FSD2 PE=4 SV=1 CANONICAL=A0A8V0Z9M3-1" }, "locus": { "chromosome": "10", "start_pos": 11110035, "end_pos": 11088157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042671.1", "url": "https://www.ensembl.org/id/ENSGALT00010042671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025161.1", "url": "https://www.ensembl.org/id/ENSGALP00010025161.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M3" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 707, "end_pos": 906, "start_aa": "Asn", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 535, "end_pos": 631, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 42 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 612, "end_pos": 614 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 814, "end_pos": 816 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9M8-1", "uniprot_ac": "A0A8V0Z9M8", "uniprot_id": "A0A8V0Z9M8_CHICK", "mass": { "chemical_mass": 58943.0, "monoisotopic_mass": 58943.0 }, "refseq": { "ac": "NP_001383844", "name": "complement component C1q receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" }, "gene_names": [ { "name": "CD93", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ] }, { "name": "C1QR1", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "CD248", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "CD93", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] } ], "protein_names": [ { "name": "CD248 molecule", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "CD93 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8/entry#names_and_taxonomy" } ] }, { "name": "complement component 1, q subcomponent, receptor 1", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "complement component C1q receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "complement component C1q receptor", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] }, { "name": "lymphocyte antigen 68", "type": "synonym", "evidence": [ { "id": "NP_001383844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: SRR13267653.21706.1, SRR13267655.8425.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM489045.1, BM427276.1, JAENSK010000060.1, AM065718.1, CR353930.1 and HAEK01163664.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8", "locus": { "chromosome": "3", "start_pos": 3508833, "end_pos": 3506465, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019399", "url": "https://www.ensembl.org/id/ENSGALG00010019399" } ] } } ], "crossref": [ { "id": "A0A8V0Z9M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03600", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03600", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421234", "url": "https://www.ncbi.nlm.nih.gov/gene/421234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YTNWHKE", "url": "https://omabrowser.org/oma/group/YTNWHKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9M8", "url": "https://www.orthodb.org/?gene=A0A8V0Z9M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14789:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14789:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVALLLLLLQLLMLVTAVAGGEDAKVLCADTACYTLHRAELGWSAAQERCQNDGGNLAPAGSRAEAERLEQLLADSMATSAWIGLRLERGHCVQSQEPLRGFSWAASGEPSNYSAWLAEPHVTCLSTRCVALRPAGPHGPLGWVDRPCRATLPAFLCKFSFRGMCGPLRLGGPGQVSYETPFRVSSPTLGAAPFGTLAEVVCEGSVSSTFSVCKGQQEGDDFTWHPPGPICPNTCTHNNGGCQQLCLEEQPGKPSLCACQPNYVLGPDMASCLPEDPCHSNPCQGTCRPQPGGFECICEAGYIVAPDGYRCVDVDECLEGPCKHECHNTAGSFFCSCQPGYQPAGPDGHDCRDEDECAQPNACPQLCLNIAGSFRCLCKAGYQQQPGSDACLDIDECLRNPCPGPCRNLPGSFECICLPGFLPQDDGHGCLTAPTTGEQLAGTMGTTAILQTASTAWTVGTPSPAAIPGGLAPPAPTVVVSEHSPEHGADGPRLLLYYILGSLVAILLLLAFALALLACRKRASRQEKTKAKSAADNYCWVPEQPESRSRAGSERR", "length": 557, "header": "tr|A0A8V0Z9M8-1|A0A8V0Z9M8_CHICK Isoform 1 of CD93 molecule OS=Gallus gallus OX=9031 GN=CD93 PE=1 SV=1 CANONICAL=A0A8V0Z9M8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8/entry#A0A8V0Z9M8-1", "sequence": { "sequence": "MAVALLLLLLQLLMLVTAVAGGEDAKVLCADTACYTLHRAELGWSAAQERCQNDGGNLAPAGSRAEAERLEQLLADSMATSAWIGLRLERGHCVQSQEPLRGFSWAASGEPSNYSAWLAEPHVTCLSTRCVALRPAGPHGPLGWVDRPCRATLPAFLCKFSFRGMCGPLRLGGPGQVSYETPFRVSSPTLGAAPFGTLAEVVCEGSVSSTFSVCKGQQEGDDFTWHPPGPICPNTCTHNNGGCQQLCLEEQPGKPSLCACQPNYVLGPDMASCLPEDPCHSNPCQGTCRPQPGGFECICEAGYIVAPDGYRCVDVDECLEGPCKHECHNTAGSFFCSCQPGYQPAGPDGHDCRDEDECAQPNACPQLCLNIAGSFRCLCKAGYQQQPGSDACLDIDECLRNPCPGPCRNLPGSFECICLPGFLPQDDGHGCLTAPTTGEQLAGTMGTTAILQTASTAWTVGTPSPAAIPGGLAPPAPTVVVSEHSPEHGADGPRLLLYYILGSLVAILLLLAFALALLACRKRASRQEKTKAKSAADNYCWVPEQPESRSRAGSERR", "length": 557, "header": "tr|A0A8V0Z9M8-1|A0A8V0Z9M8_CHICK Isoform 1 of CD93 molecule OS=Gallus gallus OX=9031 GN=CD93 PE=1 SV=1 CANONICAL=A0A8V0Z9M8-1" }, "locus": { "chromosome": "3", "start_pos": 3508188, "end_pos": 3506518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046890.1", "url": "https://www.ensembl.org/id/ENSGALT00010046890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027889.1", "url": "https://www.ensembl.org/id/ENSGALP00010027889.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 478, "start_aa": "Thr", "end_pos": 478, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr478", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HEG2-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTSTGLLLLLLLLGQSWAGAAADSEAVVCQGTACYTAHWGKVSFTEAQSSCHENGGNLATVKSEEEARYVQQALAQLLKTKEPLEAKMRKFWIGLQREKGKCTYYDLPLKGFSWVGGGEDTAYSNWYKEGKRSCTSNRCVSLILDLPLPPHPSQLPRWYETSCGTPDGNSIEGFLCKFNFKGMCSPLALGGPGQVTYTTPFQATTSSLEAVPFASAANVVCGDEAESKTYYFLCKEKTAGVFHWGSSGPLCISPKLGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGTCHPVPLSENYTCQCPKGYQLDSSQVHCVDIDECQESPCAQECINTPGSFRCECWVGYQSSGPKEATSCEDVDECAHSPCAHRCINTDGSFYCDCKDGYALSGEDSTQCEDIDECSDSRGSPCDTRCVNSEGSFTCGCQSGWELAPNGVSCIKGSVSLEPSTSSPQKEGKGDRKGNTVPPTDMPSSSRGSENVSKGGYPTGRPSLGSDTPSASVPPEIPVPSEASDVWMELDTHLPMTTGYSKPTHEDSVAAHSDSDTDGQKLLLFYILGTVVAISLLLALALGLLIYRKRRAKKEEIKEKKPQNAADSYSWVPERAESRALENQYSPTPGTDC", "length": 644 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BGJ5-1", "protein_name": "CD93 molecule", "gene_name": "CD93", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSAGLLLLLLLLSIQSRAENTTDWEAVVCAGSACYTAHRHKLSAEDAQLHCSKKGGNLATVKSEEEAWHIQGALTQLLLLGPPLQERSKFWIGLQREKGTCSDSSLPLKGFSWLGDGEDSQYNNWYKEVRSTCTHRRCVSLILDLSVPGLASGLSKWVDGPCGHSGFPGMNIEGFVCKFSFKGMCRPLTLGGPGQVNYTTPFQATSSSLQAVPFASMATVACEDGNEGRQHYFLCKEKAPSEFDWDSSGPLCVSPKFGCDFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVSCASRNPCSSNPCGGEATCFPGSLGTDFTCHCPPGYQLDSTQRDCVDVDECRDNPCAQDCVNTPGSFRCECWVGFEPGGPEEGACVDVDECAPGHSPCAQSCTNTEGSFYCSCEEGYELAEEDGTQCLDVDECEVQQGGLCDSLCFNTEGSFRCGCLPGWELDPNGVSCTGGHTSLGPPTGFPLREDTGNGEGKLQSSATVSSRSGDNPEGTSTVVPSNRRLSLPARVPTSLPPSEMLAPSATPGVWMEPSTHYPTATTGHRESAGEDFTAKQSEQGTDGQQLLLFYILGTVVAILLLLALALGLLVCRKRRAKKEEKKQQPQSAADSYAWVPERAESRAMENPYSPTPGTDC", "length": 648 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SAT8-1", "protein_name": "CD93 molecule", "gene_name": "CD93", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTSPGLLLLLLLLLVQPREGATSQEAVVCVGTACYSAHWGKLSADEAQLHCDKKGGNLATLKSEEEARHVQGTLAQLLQPGAPLAERMGRFWIGLQRDKGKCLDSDLPLKGFRWVDGVEDTPYTNWHKEAKNSCISKRCVSLLLDLSTPALASRLSKWAEGPCGSSRSPGNSVEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQATSSTLQAVPFGSMAHVACGDRDESQQPYFLCKEKAPNVFEWNSSGPLCISPKLGCDFNNGGCEQDCFEGGDGSFRCGCRPGYRLLDDLVSCASRNPCSSSPCRGGATCVPVQLGKDFRCHCPPGYQLDLTGRDCVDVDECQDAPCTQECVNTPGSFRCECWVGYEPGGPGEGACQDVDECAPGRSPCAQGCTNTIGSFSCSCEDGYILAGEEGTQCLDLDECEGQGARRCGGLCLNTEGSFRCGCLPGWELAPDGVSCTGGPTSPAPSAGTPQVQDTGDGEGEHVSSATASSPTGDPEGTSETTWVVPTTGRSSLPRHVRTSLAPPEMLVPSGTRSVWSPVGPLATPGQRESTGDDFTAKHSDSGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKEKPKNAADSYAWVPERAESRAAENPYSPTPGTDC", "length": 646 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O89103-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAISTGLFLLLGLLGQPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTGLFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTSGHSKPTHEDSVSAHSDTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC", "length": 644 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ET61-1", "protein_name": "Complement component C1q receptor", "gene_name": "Cd93", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVTSTGLLLLLGLLGQLWAGAAADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKTKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYKASKSSCISKRCVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQLTYTTPFQATTSSLKAVPFASVANVVCGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCHCPRGYQLDSSQVHCVDIDECEDSPCDQECINTPGGFHCECWVGYQSSGSKEEACEDVDECTAAYSPCAQGCTNTDGSFYCSCKEGYIMSGEDSTQCEDIDECLGNPCDTLCINTDGSFRCGCPAGFELAPNGVSCTRGSMFSELPARPPQKEDKGDGKESTVPLTEMPGSLNGSKDVSNRAQTTDLSIQSDSSTASVPLEIEVSSEASDVWLDLGTYLPTTSGHSQPTHEDSVPAHSDSDTDGQKLLLFYILGTVVAISLLLALALGLLIYLKRKAKKEEIKEKKAQNAADSYSWIPERAESRAPENQYSPTPGTDC", "length": 643 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NPY3-1", "protein_name": "Complement component C1q receptor", "gene_name": "CD93", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC", "length": 652 }, "evidence": [ { "id": "A0A8V0Z9M8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "complement component C1q complex binding", "id": "GO:0001849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001849", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 149, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9M8" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 275, "end_pos": 313, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 478 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"A0A8V0Z9N2", "uniprot_id": "A0A8V0Z9N2_CHICK", "mass": { "chemical_mass": 104692.0, "monoisotopic_mass": 104692.0 }, "refseq": {}, "gene_names": [ { "name": "GANC", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ] } ], "protein_names": [ { "name": "Glucosidase alpha, neutral C", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GANC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2", "locus": { "chromosome": "5", "start_pos": 25167638, "end_pos": 25148045, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019391", "url": "https://www.ensembl.org/id/ENSGALG00010019391" } ] } } ], "crossref": [ { "id": "A0A8V0Z9N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14752", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14752", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3S8", "url": "https://www.orthodb.org/?gene=A0A8V0Z3S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9N2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAD7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22762:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22762:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAQGEASIQDEAVDKSNFKECNQIAFYRRQKLLHPGKSLYRALLDTVTLSDENVKFHIIHEENKVLLQVEIYEIEGNIFRLKINEAAPLRARYEVPDVLIKEPTTQKLSMSQKEGGILVLTSVNGDYKLRVTANPFQVELQFKDETVLSMNSNGLLYFEHLQPPPSDRKPTAENEEAASDSSKDNQEDLGLWQERFGSFLDIKAHGPSSVGMDFSLHGFDHLYGIPQHTESLLLKNTSDGDAYRLYNLDIFGHKIHDKIGIYGSVPLLIAHKPDRTSGIFWLNSSETLVDINTKAVAEHIPTETAADISKQRAVPVTDVRWMSESGIIDVFLLMGPTAFDIFKQFAQLTGTQALPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVIWLDIEHTDGKRYFTWDKKKFQNPKKMQELLRKKKRKLVVIVDPHIKADPMYTLYSQGKEKGYFVKDRNGKDFEGICWPGSSYYLDFTNPEVRKWYADQFAFKTYKGSTNILFVWNDMNEPSVFKGAELTMQKDAVHYNNWEHRELHNLYGFYQQMATAEGLIKRSSGKERPFVLTRSFFAGSQKYVWTGDNTAEWGYLKISIPMLLTISMAGISFCGADVGGFIGDPEPELLVRWYQAGAYQPFFRGHSNMKSKRREPWLFGEKNTQIIREAIRERYVLLPYLYTLFYRAHTEAEPVMRPLWIEFPEKLETFGVEDEYMLGNALLVYPVTDKEAKAVSVLLPGSEEVWYDFRKFKRMEDRGTLKIPVTLENIPIFQRGGTVIPLKTAAGKSTEWMTNISYELRVALNTEACAVGELYLDDGHSFQYLHKKQFLYRKFTFHKNILSSSCTDESGQYRTTCVVERVIFLGLGQRPTFVTACSKGGKEKEVVFTYDTKTAVLILENLALRVDSDWEICIK", "length": 912, "header": "tr|A0A8V0Z9N2-1|A0A8V0Z9N2_CHICK Isoform 1 of Glucosidase alpha, neutral C OS=Gallus gallus OX=9031 GN=GANC PE=1 SV=1 CANONICAL=A0A8V0Z9N2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2/entry#A0A8V0Z3S8-1", "sequence": { "sequence": "MEAAAQGEASIQDEAVDKSNFKECNQIAFYRRQKLLHPGKSLYRALLDTVTLSDENVKFHIIHEENKVLLQVEIYEIEGNIFRLKINEAAPLRARYEVPDVLIKEPTTQKLSMSQKEGGILVLTSVNGDYKLRVTANPFQVELQFKDETVLSMNSNGLLYFEHLQPPPSDRKPTAENEEAASDSSKDNQEDLGLWQERFGSFLDIKAHGPSSVGMDFSLHGFDHLYGIPQHTESLLLKNTSDGDAYRLYNLDIFGHKIHDKIGIYGSVPLLIAHKPDRTSGIFWLNSSETLVDINTKAVAEHIPTETAADISKQRAVPVTDVRWMSESGIIDVFLLMGPTAFDIFKQFAQLTGTQALPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVIWLDIEHTDGKRYFTWDKKKFQNPKKMQELLRKKKRKLVVIVDPHIKADPMYTLYSQGKEKGYFVKDRNGKDFEGICWPGSSYYLDFTNPEVRKWYADQFAFKTYKGSTNILFVWNDMNEPSVFKGAELTMQKDAVHYNNWEHRELHNLYGFYQQMATAEGLIKRSSGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWGYLKISIPMLLTISMAGISFCGADVGGFIGDPEPELLVRWYQAGAYQPFFRGHSNMKSKRREPWLFGEKNTQIIREAIRERYVLLPYLYTLFYRAHTEAEPVMRPLWIEFPEKLETFGVEDEYMLGNALLVYPVTDKEAKAVSVLLPGSEEVWYDFRKFKRMEDRGTLKIPVTLENIPIFQRGGTVIPLKTAAGKSTEWMTNISYELRVALNTEPSTSPLEEEAAENWQGTNFLDMPVQ", "length": 831, "header": "tr|A0A8V0Z3S8-1|A0A8V0Z3S8_CHICK Computationally mapped isoform of Glucosidase alpha, neutral C OS=Gallus gallus OX=9031 GN=GANC PE=1 SV=1 CANONICAL=A0A8V0Z9N2-1" }, "locus": { "chromosome": "5", "start_pos": 25164577, "end_pos": 25148184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046886.1", "url": "https://www.ensembl.org/id/ENSGALT00010046886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027887.1", "url": "https://www.ensembl.org/id/ENSGALP00010027887.1" } ] } }, { "isoform_ac": "A0A8V0Z9N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2/entry#A0A8V0Z9N2-1", "sequence": { "sequence": "MEAAAQGEASIQDEAVDKSNFKECNQIAFYRRQKLLHPGKSLYRALLDTVTLSDENVKFHIIHEENKVLLQVEIYEIEGNIFRLKINEAAPLRARYEVPDVLIKEPTTQKLSMSQKEGGILVLTSVNGDYKLRVTANPFQVELQFKDETVLSMNSNGLLYFEHLQPPPSDRKPTAENEEAASDSSKDNQEDLGLWQERFGSFLDIKAHGPSSVGMDFSLHGFDHLYGIPQHTESLLLKNTSDGDAYRLYNLDIFGHKIHDKIGIYGSVPLLIAHKPDRTSGIFWLNSSETLVDINTKAVAEHIPTETAADISKQRAVPVTDVRWMSESGIIDVFLLMGPTAFDIFKQFAQLTGTQALPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVIWLDIEHTDGKRYFTWDKKKFQNPKKMQELLRKKKRKLVVIVDPHIKADPMYTLYSQGKEKGYFVKDRNGKDFEGICWPGSSYYLDFTNPEVRKWYADQFAFKTYKGSTNILFVWNDMNEPSVFKGAELTMQKDAVHYNNWEHRELHNLYGFYQQMATAEGLIKRSSGKERPFVLTRSFFAGSQKYVWTGDNTAEWGYLKISIPMLLTISMAGISFCGADVGGFIGDPEPELLVRWYQAGAYQPFFRGHSNMKSKRREPWLFGEKNTQIIREAIRERYVLLPYLYTLFYRAHTEAEPVMRPLWIEFPEKLETFGVEDEYMLGNALLVYPVTDKEAKAVSVLLPGSEEVWYDFRKFKRMEDRGTLKIPVTLENIPIFQRGGTVIPLKTAAGKSTEWMTNISYELRVALNTEACAVGELYLDDGHSFQYLHKKQFLYRKFTFHKNILSSSCTDESGQYRTTCVVERVIFLGLGQRPTFVTACSKGGKEKEVVFTYDTKTAVLILENLALRVDSDWEICIK", "length": 912, "header": "tr|A0A8V0Z9N2-1|A0A8V0Z9N2_CHICK Isoform 1 of Glucosidase alpha, neutral C OS=Gallus gallus OX=9031 GN=GANC PE=1 SV=1 CANONICAL=A0A8V0Z9N2-1" }, "locus": { "chromosome": "5", "start_pos": 25166015, "end_pos": 25148184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046913.1", "url": "https://www.ensembl.org/id/ENSGALT00010046913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027894.1", "url": "https://www.ensembl.org/id/ENSGALP00010027894.1" } ] } }, { "isoform_ac": "A0A8V0ZAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2/entry#A0A8V0ZAD7-1", "sequence": { "sequence": "MEAAAQGEASIQDEAVDKSNFKECNQIAFYRRQKLLHPGKSLYRALLDTVTLSDENVKFHIIHEENKVLLQVEIYEIEGNIFRLKINEAAPLRARYEVPDVLIKEPTTQKLSMSQKEGGILVLTSVNGDYKLRVTANPFQVELQFKDETVLSMNSNGLLYFEHLQPPPSDRKPTAENEEAASDSSKDNQEDLGLWQERFGSFLDIKAHGPSSVGMDFSLHGFDHLYGIPQHTESLLLKNTSDGDAYRLYNLDIFGHKIHDKIGIYGSVPLLIAHKPDRTSGIFWLNSSETLVDINTKAVAEHIPTETAADISKQRAVPVTDVRWMSESGIIDVFLLMGPTAFDIFKQFAQLTGTQALPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVIWLDIEHTDGKRYFTWDKKKFQNPKKMQELLRKKKRKLVVIVDPHIKADPMYTLYSQGKEKGYFVKDRNGKDFEGICWPGSSYYLDFTNPEVRKWYADQFAFKTYKGSTNILFVWNDMNEPSVFKGAELTMQKDAVHYNNWEHRELHNLYGFYQQMATAEGLIKRSSGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWGYLKISIPMLLTISMAGISFCGADVGGFIGDPEPELLVRWYQAGAYQPFFRGHSNMKSKRREPWLFGEKNTQIIREAIRERYVLLPYLYTLFYRAHTEAEPVMRPLWIEFPEKLETFGVEDEYMLGNALLVYPVTDKEAKAVSVLLPGSEEVWYDFRKFKRMEDRGTLKIPVTLENACAVGELYLDDGHSFQYLHKKQFLYRKFTFHKNILSSSCTDESGQYRTTCVVERVIFLGLGQRPTFVTACSKGGKEKEVVFTYDTKTAVLILENLALRVDSDWEICIK", "length": 876, "header": "tr|A0A8V0ZAD7-1|A0A8V0ZAD7_CHICK Computationally mapped isoform of Glucosidase alpha, neutral C OS=Gallus gallus OX=9031 GN=GANC PE=1 SV=1 CANONICAL=A0A8V0Z9N2-1" }, "locus": { "chromosome": "5", "start_pos": 25166015, "end_pos": 25148184, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046899.1", "url": "https://www.ensembl.org/id/ENSGALT00010046899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027891.1", "url": "https://www.ensembl.org/id/ENSGALP00010027891.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "pmid": "" }, { "name": "alpha-glucosidase activity", "id": "GO:0090599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 792, "end_pos": 794, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" }, { "id": "PF13802", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 31 N-terminal", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 293, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" }, { "id": "PF01055", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 31 TIM barrel", "eco_id": "ECO_0000259", "start_pos": 356, "end_pos": 681, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z9N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N2" }, { "id": "PF21365", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolase family 31 C-terminal", "eco_id": "ECO_0000259", "start_pos": 690, "end_pos": 777, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 792, "end_pos": 794 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9N3-1", "uniprot_ac": "A0A8V0Z9N3", "uniprot_id": "A0A8V0Z9N3_CHICK", "mass": { "chemical_mass": 68491.0, "monoisotopic_mass": 68491.0 }, "refseq": {}, "gene_names": [ { "name": "GMCL1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3" } ] } ], "protein_names": [ { "name": "Germ cell-less 1, spermatosis associated", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GMCL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9N3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9N3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18305", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18305", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18495", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18495", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426327", "url": "https://www.ncbi.nlm.nih.gov/gene/426327", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TGFNYGM", "url": "https://omabrowser.org/oma/group/TGFNYGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z331", "url": "https://www.orthodb.org/?gene=A0A8V0Z331", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9N3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZAG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZGE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23231:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23231:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z331", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z331", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z331-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z331-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLSSRLLRRRGGLSLGDGAAGEGGRGGGGGGRRGGKRKRGGGEGPGDSESDSDSEREERLHSAPRRKKLKSTSMYIYQTLFLNGENSDIKICALGEEWNLHKVYLRQSGYFSSMFSGSWKESCMDTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPGRVVALLAAACMLQLDGLILQCGETMKETINAKTVCSYYNSAGTYGLDSVKKRCLEWLLNNLMTHQSVELFKELSINLMKQLISSSNLFVMQVEMDLYTALKKWMFLQLVPSWNGPLKQLLAQADAWFAERRRELEGDAAFLDMEQGAAFRPVFAHLRLQYIISDLASARIVERDALIPPEWLSSVYKQQWFAMLRVEQDNDTGPQEINKEELEGSSMRCGRKLAQDGDYCWRWTGFNFGFDLLITYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKIICSRTTGYQILSLEKDQELCLEDPSGLQALGDAATEEQPSLGEVHQDVADDLPQVHPADHLLKSGVGTTGPGVGTRGQRGQPCPPHGTQHHLYGPALSGFCRGGTAPHNLSVTTTHLCFPGLRDSSSTAKSNSVWMSSKQPLSPNAPHSMLTHMRPSSPSTSSTFRISSM", "length": 619, "header": "tr|A0A8V0Z9N3-1|A0A8V0Z9N3_CHICK Isoform 1 of Germ cell-less 1, spermatosis associated OS=Gallus gallus OX=9031 GN=GMCL1 PE=4 SV=1 CANONICAL=A0A8V0Z9N3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z331-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3/entry#A0A8V0Z331-1", "sequence": { "sequence": "MGSLSSRLLRRRGGLSLGDGAAGEGGRGGGGGGRRGGKRKRGGGEGPGDSESDSDSEREERLHSAPRRKKLKSTSMYIYQTLFLNGENSDIKICALGEEWNLHKVYLRQTSVGDSISQCAHPLLGRKVLAEQRISLRWDGNLSPSSFKCLTLSLKSGYFSSMFSGSWKESCMDTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPGRVVALLAAACMLQLDGLILQCGETMKETINAKTVCSYYNSAGTYGLDSVKKRCLEWLLNNLMTHQSVELFKELSINLMKQLISSSNLFVMQVEMDLYTALKKWMFLQLVPSWNGPLKQLLAQADAWFAERRRELEGDAAFLDMEQGAAFRPVFAHLRLQYIISDLASARIVERDALIPPEWLSSVYKQQWFAMLRVEQDNDTGPQEINKEELEGSSMRCGRKLAQDGDYCWRWTGFNFGFDLLITYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKIICSRTTGYQILSLEKDQEQVVMNLDSRLLVFPLYICCNFLYTSPEKRAGGTAAPEGTDQH", "length": 555, "header": "tr|A0A8V0Z331-1|A0A8V0Z331_CHICK Computationally mapped isoform of Germ cell-less 1, spermatosis associated OS=Gallus gallus OX=9031 GN=GMCL1 PE=4 SV=1 CANONICAL=A0A8V0Z9N3-1" }, "locus": { "chromosome": "22", "start_pos": 3335400, "end_pos": 3325504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046431.1", "url": "https://www.ensembl.org/id/ENSGALT00010046431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027641.1", "url": "https://www.ensembl.org/id/ENSGALP00010027641.1" } ] } }, { "isoform_ac": "A0A8V0Z9N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3/entry#A0A8V0Z9N3-1", "sequence": { "sequence": "MGSLSSRLLRRRGGLSLGDGAAGEGGRGGGGGGRRGGKRKRGGGEGPGDSESDSDSEREERLHSAPRRKKLKSTSMYIYQTLFLNGENSDIKICALGEEWNLHKVYLRQSGYFSSMFSGSWKESCMDTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPGRVVALLAAACMLQLDGLILQCGETMKETINAKTVCSYYNSAGTYGLDSVKKRCLEWLLNNLMTHQSVELFKELSINLMKQLISSSNLFVMQVEMDLYTALKKWMFLQLVPSWNGPLKQLLAQADAWFAERRRELEGDAAFLDMEQGAAFRPVFAHLRLQYIISDLASARIVERDALIPPEWLSSVYKQQWFAMLRVEQDNDTGPQEINKEELEGSSMRCGRKLAQDGDYCWRWTGFNFGFDLLITYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKIICSRTTGYQILSLEKDQELCLEDPSGLQALGDAATEEQPSLGEVHQDVADDLPQVHPADHLLKSGVGTTGPGVGTRGQRGQPCPPHGTQHHLYGPALSGFCRGGTAPHNLSVTTTHLCFPGLRDSSSTAKSNSVWMSSKQPLSPNAPHSMLTHMRPSSPSTSSTFRISSM", "length": 619, "header": "tr|A0A8V0Z9N3-1|A0A8V0Z9N3_CHICK Isoform 1 of Germ cell-less 1, spermatosis associated OS=Gallus gallus OX=9031 GN=GMCL1 PE=4 SV=1 CANONICAL=A0A8V0Z9N3-1" }, "locus": { "chromosome": "22", "start_pos": 3338580, "end_pos": 3325504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046437.1", "url": "https://www.ensembl.org/id/ENSGALT00010046437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027645.1", "url": "https://www.ensembl.org/id/ENSGALP00010027645.1" } ] } }, { "isoform_ac": "A0A8V0ZAG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3/entry#A0A8V0ZAG8-1", "sequence": { "sequence": "MGSLSSRLLRRRGGLSLGDGAAGEGGRGGGGGGRRGGKRKRGGGEGPGDSESDSDSEREERLHSAPRRKKLKSTSMYIYQTLFLNGENSDIKICALGEEWNLHKVYLRQSGYFSSMFSGSWKESCMDTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPGRVVALLAAACMLQLDGLILQCGETMKETINAKTVCSYYNSAGTYGLDSVKKRCLEWLLNNLMTHQSVELFKELSINLMKQLISSSNLFVMQVEMDLYTALKKWMFLQLVPSWNGPLKQLLAQADAWFAERRRELEGDAAFLDMEQGAAFRPVFAHLRLQYIISDLASARIVERDALIPPEWLSSVYKQQWFAMLRVEQDNDTGPQEINKEELEGSSMRCGRKLAQDGDYCWRWTGFNFGFDLLITYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKIICSRTTGYQILSLEKDQLRVPPQEQVVMNLDSRLLVFPLYICCNFLYTSPEKRAGGTAAPEGTDQH", "length": 515, "header": "tr|A0A8V0ZAG8-1|A0A8V0ZAG8_CHICK Computationally mapped isoform of Germ cell-less 1, spermatosis associated OS=Gallus gallus OX=9031 GN=GMCL1 PE=4 SV=1 CANONICAL=A0A8V0Z9N3-1" }, "locus": { "chromosome": "22", "start_pos": 3335400, "end_pos": 3325504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046435.1", "url": "https://www.ensembl.org/id/ENSGALT00010046435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027644.1", "url": "https://www.ensembl.org/id/ENSGALP00010027644.1" } ] } }, { "isoform_ac": "A0A8V0ZGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N3/entry#A0A8V0ZGE9-1", "sequence": { "sequence": "MGSLSSRLLRRRGGLSLGDGAAGEGGRGGGGGGRRGGKRKRGGGEGPGDSESDSDSEREERLHSAPRRKKLKSTSMYIYQTLFLNGENSDIKICALGEEWNLHKVYLRQSGYFSSMFSGSWKESCMDTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPGRVVALLAAACMLQLDGLILQCGETMKETINAKTVCSYYNSAGTYGLDSVKKRCLEWLLNNLMTHQSVELFKELSINLMKQLISSSNLFVMQVEMDLYTALKKWMFLQLVPSWNGPLKQLLAQADAWFAERRRELEGDAAFLDMEQGAAFRPVFAHLRLQYIISDLASARIVERDALIPPEWLSSVYKQQWFAMLRVEQDNDTGPQEINKEELEGSSMRCGRKLAQDGDYCWRWTGFNFGFDLLITYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKIICSRTTGYQILSLEKDQELCLEDPSGLQALGDAATEEQPSLGEVHQDVADDLPQEVGDAVDDVVEELDVQSQGRRAQSPRVPCTAGSSASQQAALPPMGCCPPSLGCPRAP", "length": 560, "header": "tr|A0A8V0ZGE9-1|A0A8V0ZGE9_CHICK Computationally mapped isoform of Germ cell-less 1, spermatosis associated OS=Gallus gallus OX=9031 GN=GMCL1 PE=4 SV=1 CANONICAL=A0A8V0Z9N3-1" }, "locus": { "chromosome": "22", "start_pos": 3339464, "end_pos": 3325504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046440.1", "url": "https://www.ensembl.org/id/ENSGALT00010046440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027647.1", "url": "https://www.ensembl.org/id/ENSGALP00010027647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MJQ9-1", "protein_name": "Germ cell-less 1, spermatosis associated", "gene_name": "SNRNP27", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLLSSRVLRHPGRTRAQPEPASGAGGSARRPETGGDAPGHGFCYCPGSHKRKRNSGTFCYCNPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNTIELEIPDQNIDIEALQVAFGSLYRDDVLIKPSRVIAILAAACMLQLDGLIQQCGETMKETINVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQNVELFKELSINVMKQLIGSSNLFVMQVEMDVYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKRKKDFEGMTFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDSLVPSEWLSSVYKQQWLAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKRTENSHHPENPEN", "length": 526 }, "evidence": [ { "id": "A0A8V0Z9N3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9N3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q01820-1", "protein_name": "Protein germ cell-less", "gene_name": "gcl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQIVGSMHMNVAEVFSNRRKRKRSTDSSLGKDDPAQLDTTQPKKKKLLTTTQYIYKALFKEEKNSDVAVMALDKVWHLHKVYLSQSPYFYTMFNGTWREAQQNFIQITILDDRITVASLDAVFGSMYSDEIEIESADVISVLATATLFHLDGIIDKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQINLLSIYSKQPNLLRHISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQRAEALKTQELLVNAGVETHAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNHYMDLKIIYNDNIIPKEWLYRHIHNHWDALLRIDHGQEDCSPQQLDDEQFFENCMRCGRMLLEPGYQKWRWTGFNFGMDLILIMDSRRLNIRRHHRHEHERVLSLQTKRKFMVRTTVTSINAQRQAVFTQTSEICSLSLEKNEEVPLMVLDPKLVHPLLISINMLVVMPPNQSFKEIVPLSEEATTSLSIPISEIGANSDRPLSPSSADDSAVFIGDSEPSTPSSPAPRPRIAWSASETGAICGQLAC", "length": 569 }, "evidence": [ { "id": "A0A8V0Z9N3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9N3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q920G9-1", "protein_name": "Germ cell-less protein-like 1", "gene_name": "Gmcl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGALSSRVLRPAGRTEQPEPTPGAGGAARRSDAGEDAGHSFCYCPGGRKRKRSSGTFCYCHPDSETDDDEDEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDIEALQVAFGSLYRDDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETISVRTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQSVELFKELSINVMKQLIGSSNLFVMQVEMDVYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKWKKDFEGTTFLETEQGKPFAPVFRHLRLQYIISDLASARIIEQDSLVPSEWLAAVYKQQWLAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRATGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKRTESNRHPENPGH", "length": 524 }, "evidence": [ { "id": "A0A8V0Z9N3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9N3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96IK5-1", "protein_name": "Germ cell-less protein-like 1", "gene_name": "GMCL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSLSSRVLRQPRPALAQQAQGARAGGSARRPDTGDDAAGHGFCYCAGSHKRKRSSGSFCYCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVEALQVAFGSLYRDDVLIKPSRVVAILAAACLLQLDGLIQQCGETMKETVNVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQNVELFKELSINVMKQLIGSSNLFVMQVEMDIYTALKKWMFLQLVPSWNGSLKQLLTETDVWFSKQRKDFEGMAFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDAVVPSEWLSSVYKQQWFAMLRAEQDSEVGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKKN", "length": 515 }, "evidence": [ { "id": "A0A8V0Z9N3", "url": "https://omabrowser.org/oma/group/A0A8V0Z9N3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N3", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z9N7", "locus": { "chromosome": "22", "start_pos": 2347750, "end_pos": 2338766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019418", "url": "https://www.ensembl.org/id/ENSGALG00010019418" } ] } } ], "crossref": [ { "id": "A0A8V0Z9N7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9N7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAE7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSAHSGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNAVASAGLPAADKEPSARPAALKPPGGSGDAPPEDKSSFKPYSKGGEPRKEGPDKAGFRVPSAACPPFPPHSAASPGGSRGASPQHAEPKGADDKKEPEAGKPGPDGASGALGRGAAAEPGAHGEPPASGRKSEPPALPPAAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKAGLVGSQLPGALGLPGKPPSSSPLTGASPPSFMQGLCRDPYCLSYHSASHLGSGNCSSCVHDAGSLKSGYPLVYPAHPLHSVHTTLSSGGTPSLPGHPLYTYGFMLQNDPLPHICNWVSASGPCDKRFATSEELLTHLRTHTALPGAEKLLAGYPTSGLGSAASCHLHLPPAAPGSPSTLPASLSLRSPHTLGLNRYHPYGKSHLPAAGALPVPSLPAAGPYYSPYALYGQRLTSASALGYQ", "length": 488, "header": "tr|A0A8V0Z9N7-1|A0A8V0Z9N7_CHICK Isoform 1 of Zinc finger protein 703 OS=Gallus gallus OX=9031 GN=ZNF703 PE=3 SV=1 CANONICAL=A0A8V0Z9N7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7/entry#A0A8V0Z9N7-1", "sequence": { "sequence": "MLSAHSGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNAVASAGLPAADKEPSARPAALKPPGGSGDAPPEDKSSFKPYSKGGEPRKEGPDKAGFRVPSAACPPFPPHSAASPGGSRGASPQHAEPKGADDKKEPEAGKPGPDGASGALGRGAAAEPGAHGEPPASGRKSEPPALPPAAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKAGLVGSQLPGALGLPGKPPSSSPLTGASPPSFMQGLCRDPYCLSYHSASHLGSGNCSSCVHDAGSLKSGYPLVYPAHPLHSVHTTLSSGGTPSLPGHPLYTYGFMLQNDPLPHICNWVSASGPCDKRFATSEELLTHLRTHTALPGAEKLLAGYPTSGLGSAASCHLHLPPAAPGSPSTLPASLSLRSPHTLGLNRYHPYGKSHLPAAGALPVPSLPAAGPYYSPYALYGQRLTSASALGYQ", "length": 488, "header": "tr|A0A8V0Z9N7-1|A0A8V0Z9N7_CHICK Isoform 1 of Zinc finger protein 703 OS=Gallus gallus OX=9031 GN=ZNF703 PE=3 SV=1 CANONICAL=A0A8V0Z9N7-1" }, "locus": { "chromosome": "22", "start_pos": 2340479, "end_pos": 2338834, "strand": "-", "evidence": [ { "database": 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OX=9031 GN=ZNF703 PE=3 SV=1 CANONICAL=A0A8V0Z9N7-1" }, "locus": { "chromosome": "22", "start_pos": 2346157, "end_pos": 2344703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046925.1", "url": "https://www.ensembl.org/id/ENSGALT00010046925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027901.1", "url": "https://www.ensembl.org/id/ENSGALP00010027901.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0017015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "negative regulation of homotypic cell-cell adhesion", "id": "GO:0034111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9N7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 392, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 337 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 301, "end_pos": 303 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9P8-1", "uniprot_ac": "A0A8V0Z9P8", "uniprot_id": "A0A8V0Z9P8_CHICK", "mass": { "chemical_mass": 149180.0, "monoisotopic_mass": 149180.0 }, "refseq": { "ac": "XP_418790", "name": "nephrocystin-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418790" }, "gene_names": [ { "name": "NPHP3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ] }, { "name": "NPHP3", "type": "synonym", "evidence": [ { "id": "XP_418790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418790" } ] } ], "protein_names": [ { "name": "Nephrocystin-3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8/entry#names_and_taxonomy" } ] }, { "name": "nephrocystin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418790" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418790.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418790" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPHP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8", "locus": { "chromosome": "2", "start_pos": 42253615, "end_pos": 42279744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018977", "url": "https://www.ensembl.org/id/ENSGALG00010018977" } ] } } ], "crossref": [ { "id": "420690", "url": "https://www.ncbi.nlm.nih.gov/gene/420690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FKIHQKA", "url": "https://omabrowser.org/oma/group/FKIHQKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9P8", "url": "https://www.orthodb.org/?gene=A0A8V0Z9P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45641", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45641", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45641:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45641:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5624138", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624138", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418790", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTASSLVSPAGGVGEVIEDTYGGGEACEIPVEVKPKARLLRGSLRRVGASRPGGLIGASFKSTASVQELECVAEYERLKKEYEIFRVSKNNEVASMVKKEAKLDRENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKENEIQDLLRAKRDLEAKLQRLQAQGIQVFDPEESDSDDNCTDVTAAGAQSEYWNGGALGSEPSMGSMMQLQQSFRGPEFAHSSIDVEGPFANINRDDWDAAVASILQVTPLFSHSLWSNTVRCFIISTDETQPEVEIFIRIYSPKLQRICETMGYFFQVVHFPAENENHSKEVRKWEIEKSSLVILLLHLTLPSCLLEDCEEAFLKNPEEKPRLIYHRMGDDRVSSDSVQQLIEQISNVNKAKMIDHVGDVEEGTYEIYTCVEKIIKQDILGCEMTELEGKDLGNKEESTAPEEEVFGDVLWDAHDEQEQMEAFQQASNSTCELGFEKYFERLNDLVAAPAPIPPLLVSGGPGSGKSLLLSKWIHLQQKHSPNTLILYHFVGRPMSTSSESALIIKRLTLKLMQHSWLVSPLTLDPAKLLEEFPRWLEKLSARHQGSIIIIIDSIDQIQQAEKHMKWLIDPLPVNVRVIVSVNVETCPQAWRLWPTLHLDPLNSKDVKALISAECSSANIKLTKEQEKKLERHCRSATTCNALYVTLLGKTIARVGSTGNIDETLQQCFQCQDTVSLYRLVLRSIQQSLCSDKEKGLLREILCVIGVSHNGVSESELMELYPELSSAVLASLVHSLHKMCLLTYGCGLLKFQHLQAWEMVRLEYMEEGPNVISAYRQKLVDYFTMQLSRDRVTWRSADELPWLFQQQGDKQKLHKCLLNLFVSQNLYKRGHFAELLSYWQLVGKDKSSMAAEYFDSLKEYEKSCEGEESMICLADLYETLGRFLKDLGLLSQAVAPLQRSLEIRETALDPDHPRVAQSLHQLAGVYVQWKKFGNAEQLYKQALEISENAYGAEHPRVARELDALAMLYQKQNKYEQAEQLRKKSFKIRQKAARRKGSLCGFALLRQRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETAELFLKRSLEMRERVLGPNHPDCAQSLNNLAALYNEKKHYDKAEELYEKALDIRRRALAPDHPSLAYTVKHLAVLYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYCQMKKQTEALPLYERALKIYEDSFGHMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAETLLIGGKAISRHSSSGDTFSLKSALSPNIFLEPGQR", "length": 1315, "header": "tr|A0A8V0Z9P8-1|A0A8V0Z9P8_CHICK Isoform 1 of Nephrocystin-3 OS=Gallus gallus OX=9031 GN=NPHP3 PE=4 SV=1 CANONICAL=A0A8V0Z9P8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8/entry#A0A8V0Z9P8-1", "sequence": { "sequence": "MGTASSLVSPAGGVGEVIEDTYGGGEACEIPVEVKPKARLLRGSLRRVGASRPGGLIGASFKSTASVQELECVAEYERLKKEYEIFRVSKNNEVASMVKKEAKLDRENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKENEIQDLLRAKRDLEAKLQRLQAQGIQVFDPEESDSDDNCTDVTAAGAQSEYWNGGALGSEPSMGSMMQLQQSFRGPEFAHSSIDVEGPFANINRDDWDAAVASILQVTPLFSHSLWSNTVRCFIISTDETQPEVEIFIRIYSPKLQRICETMGYFFQVVHFPAENENHSKEVRKWEIEKSSLVILLLHLTLPSCLLEDCEEAFLKNPEEKPRLIYHRMGDDRVSSDSVQQLIEQISNVNKAKMIDHVGDVEEGTYEIYTCVEKIIKQDILGCEMTELEGKDLGNKEESTAPEEEVFGDVLWDAHDEQEQMEAFQQASNSTCELGFEKYFERLNDLVAAPAPIPPLLVSGGPGSGKSLLLSKWIHLQQKHSPNTLILYHFVGRPMSTSSESALIIKRLTLKLMQHSWLVSPLTLDPAKLLEEFPRWLEKLSARHQGSIIIIIDSIDQIQQAEKHMKWLIDPLPVNVRVIVSVNVETCPQAWRLWPTLHLDPLNSKDVKALISAECSSANIKLTKEQEKKLERHCRSATTCNALYVTLLGKTIARVGSTGNIDETLQQCFQCQDTVSLYRLVLRSIQQSLCSDKEKGLLREILCVIGVSHNGVSESELMELYPELSSAVLASLVHSLHKMCLLTYGCGLLKFQHLQAWEMVRLEYMEEGPNVISAYRQKLVDYFTMQLSRDRVTWRSADELPWLFQQQGDKQKLHKCLLNLFVSQNLYKRGHFAELLSYWQLVGKDKSSMAAEYFDSLKEYEKSCEGEESMICLADLYETLGRFLKDLGLLSQAVAPLQRSLEIRETALDPDHPRVAQSLHQLAGVYVQWKKFGNAEQLYKQALEISENAYGAEHPRVARELDALAMLYQKQNKYEQAEQLRKKSFKIRQKAARRKGSLCGFALLRQRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETAELFLKRSLEMRERVLGPNHPDCAQSLNNLAALYNEKKHYDKAEELYEKALDIRRRALAPDHPSLAYTVKHLAVLYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYCQMKKQTEALPLYERALKIYEDSFGHMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAETLLIGGKAISRHSSSGDTFSLKSALSPNIFLEPGQR", "length": 1315, "header": "tr|A0A8V0Z9P8-1|A0A8V0Z9P8_CHICK Isoform 1 of Nephrocystin-3 OS=Gallus gallus OX=9031 GN=NPHP3 PE=4 SV=1 CANONICAL=A0A8V0Z9P8-1" }, "locus": { "chromosome": "2", "start_pos": 42279578, "end_pos": 42254421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045931.1", "url": "https://www.ensembl.org/id/ENSGALT00010045931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027363.1", "url": "https://www.ensembl.org/id/ENSGALP00010027363.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5624138", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624138", "resource": "Reactome", "description": "Trafficking of myristoylated proteins to the cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AZU2-1", "protein_name": "Nephrocystin-3", "gene_name": "NPHP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRNSFRRGAGAAAAGAGPGSLPRGAGGGGLLGASFKSTGSSVPELEYAAAEYERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIHVFDPGESDSDDNCTDVTAAGTQCEYWTGGALGSEPSLGSMIQLQQSFRGPEFAHSSIDVEGPFANVNRDDWDIAVASLLQVTPLFSHSLWSNTVRCYLIYTDETQPEMDLFLKDYSPKLKRMCETMGYFFHAVYFPIDIENQYLTVRKWEIEKSSLVILFIHLTLPSLLLEDCEEAFLKNPEGKPRLIYHRLEDGKVTTDSVQQLIAQVSNLKTNKAKIIEHSGDPAEGVHKTYIYVEKIIKQDILGFENTDPDTKDLGSEDSVPEEDDFGDVLWDIHDEQEQMEAFQQASNSAHELGFEKYYQRLNDLVAAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKNSPNTLILSHFVGKPMSTSSESSLVIKRLTLKLMQHSWSVSALTLDPAKLLEEFPRWLEKLSARHQGSIIIIIDSIDQIQQVEKHMKWLIDPLPVNVRVIVSVNVETCPPAWRLWPTLHLDPLSPKDAKSIIIAECHSVGIKLSKEQEKKLERHCRSATTCNALYVTLFGKMIARAGRAGNLDKILLQCFQCQDTVSLYRLTLHSIQESMANDIDKELMRQILCLVNVSHNGVSESELMELYPEMSWAVLTSLIHSLHKMCLLTYGCGLLKFQHLQAWETVRLEYMEDPAIISSYRQKLTNYFTVQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLFVSQNLYKRGHFAELLSYWQFVGKDKSAMAAEYFDSLKRYEKNCDGEESMICLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLFKQALEISENAYGVDHPHIARELEALATLYQKQNKYEQAEHFRKKSFKIRQKATRRKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHIEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGDFEKAAELYKRAMEIKEAETSLLGGKAPSRHSSSGDTFSLKTHSPNTFLHQGQR", "length": 1329 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A1W7-1", "protein_name": "Nephrocystin-3", "gene_name": "Nphp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGAGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQVLQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNGADVTAAGTQCEYWASRALGSEHSIDSMIQLQQPFRGPEFAHSSIDVEGPFANINRDDWDAAVAGLLQATPLFSHSLWCHPVRCYLIYSEETQPEMELFLKDHSPKLKRMCETMGYFFHAVYFPIDVENQYLTLRKWEIEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKLRLIYHRLEDGKATSDSVQRLLDQVSNLSETTKAKIIEHSGDLSEGVYKIYMGVEKIIKQDILGLENTDVEVKDGGSEDSSPEEDDFGDVLWDVHDEQEQIEAFQRASSSAHELGFEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKHFPNTLILSHFVGRPMSSSSESSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSIIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPTAWRLWPTLHLDPLSPKDAISMITAECHSVDVQLNREQEKMLEQHCRPATTRHALYVTLFSKMLACAGRAGDLAETLHRCLQCQDTMSLYRLVLHHVRESMPSDKEKEWMTQILCLINVSHNGVSESELMELYPEMSWASLTSIVHSLHKMHLLTYSCGLLRFQHLQAWETVRQAYMEDPALVSSYRQKLIDYFTSQLSQDRVTWRSADELPWLFQQQGSKQKLHSCLLNLFVSQNLYKRGHFAELLSYWQFVGKDKSAMATEYFESLKQYENCEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLAGVYVQWKKFSDAEQLYKQALEISENAYGADHPHAARELEALATLYHKQNKYEQAERFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYYLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNERKQYARAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGRVDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGNFEKAAELYKRAMEIKEAETSLLGGKAPSRQSSSGDTLLFKTTHSPNVFLPQGQS", "length": 1325 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BP93-1", "protein_name": "Nephrocystin-3", "gene_name": "NPHP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRAAGVAAAGAGPGSLPRGAGGGGLLGASFKSTGSSVPELEYAAAEYERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIHVFDPGESDSDDNCTDVTAAGTQCEYWTGGALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANVNRDDWDIAVASLLQVTPLFSHSLWSNTVRCYLIHTDETQPEMDLFLKDYSPKLKRMCETMGYFFHAVYFPIDIENQYLAVRKWEIEKSSLVILFIHLTLPSLLLEDCEEAFLKNPEGKPRLIYHRLEDGKVSSDSVQQLIDQVSNLNKTSKAKIIDHLGDPAEGVYKTYIYVEKIIKQDILGFENTDLDTKDLGSEDSIPEEDDFGDVLWDIHDEQEQMEAFQQASNSAHELGFEKYYQRLNDLVAAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKNSPNTLILSHFVGRPMSTSSEASLIIKRLTLKLMQHSWSVSALTLDPAKLLEEFPRWLEKLSARHQGSIIIIIDSIDQIQQVEKHMKWLIDPLPVNVRVIVSVNVETCPPAWRLWPTLHLDPLNPKDAKSIIIAECHSVDIKLSKEQEKKLERHCRSATTCNALYVTLFGKMIARAGRAGNLDKILLQCFQCQDTVSLYRLVLRSIQESLANDTDKELMKQILCLVNISHNGVNESELMELYPEMSWTVLTSLIHSLHKMCLLTYGCGLLKFQHLQAWETVRLEYMESPTIIASYRQKLTNYFTMQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLFVSQNLYKRGHFAELLSYWQFVGKDKSAMAAEYFDSLKQYEKNCEGEESMVCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPQVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPHTARELEALATLYQKQDKYEQAEHFRKKSFKIRQKAARRKGNLYGFSLLRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLEIADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGDFEKAAELYKRAMEIKEAETSLLGGKAPSQHSSSGDTFSLKTTHSPNLFLHQGQR", "length": 1331 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0CI65-1", "protein_name": "Nephrocystin-3", "gene_name": "nphp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTASSLVSPGEVIEDAYGGEGGEACEIPVEVKPKARLLRSSFRRGPRVIGASFKSTGSVELEYAAEYERLRKDYEIFRVSKNNEITSMQKKEAKLDEENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKEKEIQDLLRAKRDLESKLQQLQAQGIQIYDPADSDSDDNHTTVTTAGTQCEYWSGGVLGSEPSMGSMMQLQQTHRGPEFAHSLIDVEGPFANVSRDDWDAAVASLLQVSPHVSQSLWSNTVRCYLIYTHETKAELQTFIQTYSLRLRRFCEGLGHFYLNVSFPEEKAAVFAAERRREMERSSVCVLLLKSSVSSCVVEDVEEAFVKTPDARPLLLYLRTADRKGEKEEVSTLSPATRDLLERVNKADRSAKLKVVDHAGSVEEGAALIFSQLERIIKQELLGLELEENGVVEEREEEDSGDVLWDLHDEQEQIEAFQQACGAAARFSFQKYVDRLNDMVAAPPPTPPLLVSGAPGSGKSLLLAKWIELQQKHSPNTLILYHFTGRPLSTSTDPVLIIKRLTVKLLQHFWSISGLSMDPSKILEEFPRWLERLSARHHGNIIIIIDSIDQIQNAERHMKWLIDPLPANVRVLVSVNVETCPQAWRLWPTLHLDPLNPREVKSVISTECVSVDIKLSKDQEKKLEKHCRSAATCNALYVSLLARLITHFSTSWTLDRTLQQCVMCQDTVSLYRLGLKVALDSLNSDQEKHIMKELLCLVCASHNGISESEVLELFPDLTFPALISMLHNLERLLIITYACGLIRFQHSQACEGVNQEFLDGDKCRGSYREKCIRFFSQQLEQDRVTWRVADELPWLLQQQEDRSKLQMSLLNLFVSQNLYKRGHFSELLAYWQFVGKDKCSMATEYFDALKEFEKTCESEQSMSRLANLYETLGRFLKDLGLLSQAVAPLQRSLEIRETALDPDHPSVAQSLHQLAGVYVHWRKFGNAEQLYKQAMEICENAYGPEHSTVARELDSLSLLYQKQNKYEQAEKLRKRSVKIRQKTARQKGHMYGFALLKRRALQLEELTLGKDSTDCAKTLNELGVLYYLQNNLDAAKLFLTRSLEMRQRVLGPDHPDCAQSLNNLAALHSERKEYESAEELYERALDIRKRALAPDHPSLAYTLKHLAMLYKRRGKLEKAVPLYELALEIREKSFGPKHPSVATALVNLAVLYCQLKQHSDALPLYERALKVYEDSLGRLHPRVGETLKNLAVLSYEEGDFEKAAELYKRAMEIKEAEPSLVCGKAPSRHSSSGDTFSMRSPALPNASR", "length": 1303 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TNH6-1", "protein_name": "Nephrocystin-3", "gene_name": "Nphp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTASSLVSPTGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWASRALGSEHSIGSMIQLPQPFRGPEFAHSSIDVEGPFANINRDDWDAAVAGLLQATPLFSHSLWSHPVRCYLIYTDETQPEMELFLKDHSPKLKRMCETMGYFFLAVYFPLDVENQYLTVRKWEIEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPGLIYHRLEDGKVTCDSVQQFLDQVSNLGKTTKAKIIEHSGDPAEGVCKIYVGVEKIIKQDILGLENTDVEEKDGGREDSTPEEDDFGDVLWDIHDEQEQMEAFQQTSSSAHELGFEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKHFPNTLILSHFVGRPMSTSSESSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSIIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPTAWRLWPTLHLDPLSPKDAISIITAECYSMDVRLSREQEKMLEQHCRPATTRHALYVTLFSKMMACAGRGGNVAETLHQCLQCQDTVSLYKLVLHHVRESMPSDRDKEWMTQILCLINVSHNGVSESELMELYPEMSWLSLTSIVHSLHKMHLLTYSCGLLRFQHLQAWETVRLQYLEDPALVSSYREKLISYFASQLSQDRVTWRSADELPWLFQQQGSKQKLHSCLLNLLVAQNLYKRGHFAELLSYWQFVGKDKGAMATEYFESLKQYENSEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLAGVYVQWKKFGDAEQLYKQALEISENAYGADHPHAARELEALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYFLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGKVDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGNFEKAAELYKRAMEIKEAETSLLGGKAPSRQSSSGDTFLFKTTHSPNVFLPQGQS", "length": 1325 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z494-1", "protein_name": "Nephrocystin-3", "gene_name": "NPHP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRNSFRRGAGAAAGAGPGSLPRGVGAGGLLGASFKSTGSSVPELEYAAAEYERLRKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWTGGALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANVNRDDWDIAVASLLQVTPLFSHSLWSNTVRCYLIYTDETQPEMDLFLKDYSPKLKRMCETMGYFFHAVYFPIDVENQYLTVRKWEIEKSSLVILFIHLTLPSLLLEDCEEAFLKNPEGKPRLIFHRLEDGKVSSDSVQQLIDQVSNLNKTSKAKIIDHSGDPAEGVYKTYICVEKIIKQDILGFENTDLETKDLGSEDSIPEEDDFGDVLWDIHDEQEQMETFQQASNSAHELGFEKYYQRLNDLVAAPAPIPPLLVSGGPGSGKSLLLSKWIQLQQKNSPNTLILSHFVGRPMSTSSESSLIIKRLTLKLMQHSWSVSALTLDPAKLLEEFPRWLEKLSARHQGSIIIVIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPPAWRLWPTLHLDPLSPKDAKSIIIAECHSVDIKLSKEQEKKLERHCRSATTCNALYVTLFGKMIARAGRAGNLDKILHQCFQCQDTLSLYRLVLHSIRESMANDVDKELMKQILCLVNVSHNGVSESELMELYPEMSWTFLTSLIHSLYKMCLLTYGCGLLRFQHLQAWETVRLEYLEGPTVTSSYRQKLINYFTLQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLFVSQNLYKRGHFAELLSYWQFVGKDKSAMATEYFDSLKQYEKNCEGEDNMSCLADLYETLGRFLKDLGLLSQAIVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAETSLLGGKAPSRHSSSGDTFSLKTAHSPNVFLQQGQR", "length": 1330 }, "evidence": [ { "id": "A0A8V0Z9P8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9P8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "kidney morphogenesis", "id": "GO:0060993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "maintenance of animal organ identity", "id": "GO:0048496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "atrial septum development", "id": "GO:0003283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "ureter development", "id": "GO:0072189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "determination of pancreatic left/right asymmetry", "id": "GO:0035469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "determination of liver left/right asymmetry", "id": "GO:0071910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071910", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "determination of intestine left/right asymmetry", "id": "GO:0071908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "determination of stomach left/right asymmetry", "id": "GO:0071909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "convergent extension", "id": "GO:0060026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "ciliary inversin compartment", "id": "GO:0097543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9P8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0ZMV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GGPELLHPTLSSLLPCWVRHCSWGVSVPAALLDLQELQTVGIILPLCSSFKLLHVLGIVDPSGGGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 292, "header": "tr|A0A8V0Z9Q8-1|A0A8V0Z9Q8_CHICK Isoform 1 of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0Z9Q8-1", "sequence": { "sequence": "GGPELLHPTLSSLLPCWVRHCSWGVSVPAALLDLQELQTVGIILPLCSSFKLLHVLGIVDPSGGGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 292, "header": "tr|A0A8V0Z9Q8-1|A0A8V0Z9Q8_CHICK Isoform 1 of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23460669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050816.1", "url": "https://www.ensembl.org/id/ENSGALT00010050816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030007.1", "url": "https://www.ensembl.org/id/ENSGALP00010030007.1" } ] } }, { "isoform_ac": "A0A8V0Z9T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0Z9T0-1", "sequence": { "sequence": "MRSKGRKESLSDSRDLDGSYDQLTDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 220, "header": "tr|A0A8V0Z9T0-1|A0A8V0Z9T0_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23445838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050846.1", "url": "https://www.ensembl.org/id/ENSGALT00010050846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030037.1", "url": "https://www.ensembl.org/id/ENSGALP00010030037.1" } ] } }, { "isoform_ac": "A0A8V0ZFF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZFF9-1", "sequence": { "sequence": "PYHNQGGCWRQGDSVPSPAEPLGAPKPGQQSASPGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 262, "header": "tr|A0A8V0ZFF9-1|A0A8V0ZFF9_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23461690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050808.1", "url": "https://www.ensembl.org/id/ENSGALT00010050808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029999.1", "url": "https://www.ensembl.org/id/ENSGALP00010029999.1" } ] } }, { "isoform_ac": "A0A8V0ZGS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGS7-1", "sequence": { "sequence": "PTARAHTCCPCNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 238, "header": "tr|A0A8V0ZGS7-1|A0A8V0ZGS7_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23461963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050840.1", "url": "https://www.ensembl.org/id/ENSGALT00010050840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030031.1", "url": "https://www.ensembl.org/id/ENSGALP00010030031.1" } ] } }, { "isoform_ac": "A0A8V0ZGV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGV3-1", "sequence": { "sequence": "MNLEGLEMVAVLVVLVLFVKVLEQFGLFEPVSLEGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSENSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 262, "header": "tr|A0A8V0ZGV3-1|A0A8V0ZGV3_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23458626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050819.1", "url": "https://www.ensembl.org/id/ENSGALT00010050819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030010.1", "url": "https://www.ensembl.org/id/ENSGALP00010030010.1" } ] } }, { "isoform_ac": "A0A8V0ZGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGV5-1", "sequence": { "sequence": "MERTSLHNDSLLYASLIAILLLISYWFTTRCFKIISGIEDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 235, "header": "tr|A0A8V0ZGV5-1|A0A8V0ZGV5_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23456318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050824.1", "url": "https://www.ensembl.org/id/ENSGALT00010050824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030015.1", "url": "https://www.ensembl.org/id/ENSGALP00010030015.1" } ] } }, { "isoform_ac": "A0A8V0ZGV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGV9-1", "sequence": { "sequence": "MSHCQQRCKRQLGRVIRCFYQFVTGTLSQGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 257, "header": "tr|A0A8V0ZGV9-1|A0A8V0ZGV9_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23454204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050828.1", "url": "https://www.ensembl.org/id/ENSGALT00010050828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030020.1", "url": "https://www.ensembl.org/id/ENSGALP00010030020.1" } ] } }, { "isoform_ac": "A0A8V0ZGW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGW4-1", "sequence": { "sequence": "MSHCQQRCKRQLGRVIRCFYQFVTGTLSQDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 225, "header": "tr|A0A8V0ZGW4-1|A0A8V0ZGW4_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23454204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050834.1", "url": "https://www.ensembl.org/id/ENSGALT00010050834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030025.1", "url": "https://www.ensembl.org/id/ENSGALP00010030025.1" } ] } }, { "isoform_ac": "A0A8V0ZGX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZGX1-1", "sequence": { "sequence": "MRSKGRKESLSDSRDLDGSYDQLTGNPPGQTKKALKQRFLKLLPCCRPKSIPSLSESNVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 252, "header": "tr|A0A8V0ZGX1-1|A0A8V0ZGX1_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23445838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050844.1", "url": "https://www.ensembl.org/id/ENSGALT00010050844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030035.1", "url": "https://www.ensembl.org/id/ENSGALP00010030035.1" } ] } }, { "isoform_ac": "A0A8V0ZMV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8/entry#A0A8V0ZMV7-1", "sequence": { "sequence": "TAASHTLLSPALLGQALQLGGVSPCCALGPAGAANSGHHPASLLQLQAAPRPGHRRPEWGSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTDHDGSVSFEDFVSGLSIILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPAMREEAPREHVENFFQKMDRNKDGVVTIEEFLESCQKDENIMRSMQLFDNVI", "length": 255, "header": "tr|A0A8V0ZMV7-1|A0A8V0ZMV7_CHICK Computationally mapped isoform of Potassium voltage-gated channel interacting protein 2 OS=Gallus gallus OX=9031 GN=KCNIP2 PE=3 SV=1 CANONICAL=A0A8V0Z9Q8-1" }, "locus": { "chromosome": "6", "start_pos": 23465984, "end_pos": 23460680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050812.1", "url": "https://www.ensembl.org/id/ENSGALT00010050812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030003.1", "url": "https://www.ensembl.org/id/ENSGALP00010030003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5576894", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576894", "resource": "Reactome", "description": "Phase 1 - inactivation of fast Na+ channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AL95-1", "protein_name": "Potassium voltage-gated channel interacting protein 2", "gene_name": "KCNIP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGQGRKESLSDSRDLDGSYDQLTDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTTDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI", "length": 220 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GS34-1", "protein_name": "Kv channel-interacting protein 2 isoform X4", "gene_name": "Kcnip2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRGQGRKESLSESRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSEISTGLGLLGDNSLPSALAAPASLRPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVFGLSVILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKHTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI", "length": 285 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SYI1-1", "protein_name": "Potassium voltage-gated channel interacting protein 2", "gene_name": "KCNIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRCPRRCRSPLGQAARSLYQLVTGSLSPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTTDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI", "length": 225 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JJ69-1", "protein_name": "A-type potassium channel modulatory protein KCNIP2", "gene_name": "Kcnip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGQGRKESLSDSRDLDGSYDQLTGHPPGPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQLFDNVI", "length": 270 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JM59-1", "protein_name": "A-type potassium channel modulatory protein KCNIP2", "gene_name": "Kcnip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGQGRKESLSESRDLDGSYDQLTGHPPGPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQLFDNVI", "length": 270 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NS61-1", "protein_name": "A-type potassium channel modulatory protein KCNIP2", "gene_name": "KCNIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGQGRKESLSDSRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRLLDPDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI", "length": 270 }, "evidence": [ { "id": "A0A8V0Z9Q8", "url": "https://omabrowser.org/oma/group/A0A8V0Z9Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "regulation of membrane repolarization", "id": "GO:0060306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "positive regulation of potassium ion export across plasma membrane", "id": "GO:1903766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "membrane repolarization", "id": "GO:0086009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "clustering of voltage-gated potassium channels", "id": "GO:0045163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q8" } ], "pmid": "" }, { "name": "calcium ion binding", 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"A0A8V0Z9V2_CHICK", "mass": { "chemical_mass": 73022.0, "monoisotopic_mass": 73022.0 }, "refseq": { "ac": "NP_001006396", "name": "WD repeat-containing protein 43", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006396" }, "gene_names": [ { "name": "WDR43", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ] }, { "name": "WDR43", "type": "synonym", "evidence": [ { "id": "NP_001006396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006396" } ] } ], "protein_names": [ { "name": "WD repeat domain 43", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 43", "type": "synonym", "evidence": [ { "id": "NP_001006396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006396" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719412.1, SRR13267659.273611.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000061.1. On Sep 23, 2021 this sequence version replaced NP_001006396.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006396" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2", "locus": { "chromosome": "3", "start_pos": 8768736, "end_pos": 8811081, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017677", "url": "https://www.ensembl.org/id/ENSGALG00010017677" } ] } } ], "crossref": [ { "id": "A0A8V0Z9V2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9V2", "database": "AlphaFoldDB", "categories": [] }, { "id": "421295", "url": "https://www.ncbi.nlm.nih.gov/gene/421295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421295", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421295", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCTALTW", "url": "https://omabrowser.org/oma/group/PCTALTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2U0", "url": "https://www.orthodb.org/?gene=A0A8V0Z2U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2U5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9U7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9U7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9V2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44267:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44267:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAACGGEVAARPPLAFSPHDRRFLAVSGSDGRLRVWDTVGSRLQHEYVPSAHLSAACTCLAWAPPGGRPPPDKDGPQRKKRKSEAAEVDKQLDILAIGTAVGSILLYSTVKGELQSKLDGGHDSRINCVRWHQDNCCLYSCSEDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWDLETKEVYRHFTGHATSVSSLMFTTVKPMNENKPFDGITGLYFLSGAIHDRLLSVWQIRSDRKEKNAVMSFTVTDEPTFIDLTVSELKEEPVKLAVVCKDGQLHLFEHILNGYCKKPLTSNCTIQIATPGNDGDSTPKPVPILAAAFCTDKQSLLLVYGNTLQPIIEKVSLNTSESHICLIRDVQKALALKTDDAVTKVRTPVVNSDTKVLVPGIPGHSAAVKTPSSGKEKKKSKRKPGETEDSIEERLGALDIDVSKVKTPGGLPQTDSFAVLLVQGLESNDEDILNKVLSTRKETLIKNTVARMPIHAVIPLLHELTKRLQGNPYSASQMVRWLKFVFTLHASYLSTLPDLIPQLGMLYQLMESRVKTLQKLSRLHGRLFLLVTQVAASETVQDVTEVNQTAKLVYEDESSEEEGSDDEMIADKDSDENWDEDEEKEEQSDEQDMTVEKEMNGDSDLEPENESEEE", "length": 661, "header": "tr|A0A8V0Z9V2-1|A0A8V0Z9V2_CHICK Isoform 1 of WD repeat domain 43 OS=Gallus gallus OX=9031 GN=WDR43 PE=1 SV=1 CANONICAL=A0A8V0Z9V2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2/entry#A0A8V0Z2U0-1", "sequence": { "sequence": "MAAAAACGGEVAARPPLAFSPHDRRFLAVSGSDGRLRVWDTVGSRLQHEYVPSAHLSAACTCLAWAPPGGRPPPDKDGPQRKKRKSEAAEVDKQLDILAIGTAVGSILLYSTVKGELQSKLDGGHDSRINCVRWHQDNCCLYSCSEDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWDLETKEVYRHFTGHATSVSSLMFTTVKPMNENKPFDGITGLYFLSGAIHDRLLSVWQIRSDRKEKNAVMSFTVTDEPTFIDLTVSELKEEPVKLAVVCKDGQLHLFEHILNGYCKKPLTSNCTIQIATPGNDGDSTPKPVPILAAAFCTDKQSLLLVYGNTLQPIIEKVRTPVVNSDTKVLVPGIPGHSAAVKTPSSGKEKKKSKRKPGETEDSIEERLGALDIDVSKVKTPGGLPQTDSFAVLLVQGLESNDEDILNKVLSTRKETLIKNTVARMPIHAVIPLLHELTKRLQGNPYSASQMVRWLKFVFTLHASYLSTLPDLIPQLGMLYQLMESRVKTLQKLSRLHGRLFLLVTQVAASETVQDVTEVNQTAKLVYEDESSEEEGSDDEMIADKDSDENWDEDEEKEEQSDEQDMTVEKEMNGDSDLEPENESEEE", "length": 631, "header": "tr|A0A8V0Z2U0-1|A0A8V0Z2U0_CHICK Computationally mapped isoform of WD repeat domain 43 OS=Gallus gallus OX=9031 GN=WDR43 PE=1 SV=1 CANONICAL=A0A8V0Z9V2-1" }, "locus": { "chromosome": "3", "start_pos": 8811051, "end_pos": 8789760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042744.1", "url": "https://www.ensembl.org/id/ENSGALT00010042744.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025234.1", "url": "https://www.ensembl.org/id/ENSGALP00010025234.1" } ] } }, { "isoform_ac": "A0A8V0Z2U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2/entry#A0A8V0Z2U5-1", "sequence": { "sequence": "MGGSACGTRWAAACTCLAWAPPGGRPPPDKDGPQRKKRKSEAAEVDKQLDILAIGTAVGSILLYSTVKGELQSKLDGGHDSRINCVRWHQDNCCLYSCSEDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWDLETKEVYRHFTGHATSVSSLMFTTVKPMNENKPFDGITGLYFLSGAIHDRLLSVWQIRSDRKEKNAVMSFTVTDEPTFIDLTVSELKEEPVKLAVVCKDGQLHLFEHILNGYCKKPLTSNCTIQIATPGNDGDSTPKPVPILAAAFCTDKQSLLLVYGNTLQPIIEKVSLNTSESHICLIRDVQKALALKTDDAVTKVRTPVVNSDTKVLVPGIPGHSAAVKTPSSGKEKKKSKRKPGETEDSIEERLGALDIDVSKVKTPGGLPQTDSFAVLLVQGLESNDEDILNKVLSTRKETLIKNTVARMPIHAVIPLLHELTKRLQGNPYSASQMVRWLKFVFTLHASYLSTLPDLIPQLGMLYQLMESRVKTLQKLSRLHGRLFLLVTQVAASETVQDVTEVNQTAKLVYEDESSEEEGSDDEMIADKDSDENWDEDEEKEEQSDEQDMTVEKEMNGDSDLEPENESEEE", "length": 615, "header": "tr|A0A8V0Z2U5-1|A0A8V0Z2U5_CHICK Computationally mapped isoform of WD repeat domain 43 OS=Gallus gallus OX=9031 GN=WDR43 PE=1 SV=1 CANONICAL=A0A8V0Z9V2-1" }, "locus": { "chromosome": "3", "start_pos": 8810954, "end_pos": 8789760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042749.1", "url": "https://www.ensembl.org/id/ENSGALT00010042749.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025239.1", "url": "https://www.ensembl.org/id/ENSGALP00010025239.1" } ] } }, { "isoform_ac": "A0A8V0Z9U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2/entry#A0A8V0Z9U7-1", "sequence": { "sequence": "MAAAAACGGEVAARPPLAFSPHDRRFLAVSGSDGRLRVWDTVGSRLQHEYVPSAHLSAACTCLAWAPPGGRPPPDKDGPQRKKRKSEAAEVDKQLDILAIGTAVGSILLYSTVKGELQSKLDGGHDSRINCVRWHQDNCCLYSCSEDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWDLETKEVYRHFTGHATSVSSLMFTTVKPMNENKPFDGITGLYFLSGAIHDRLLSVWQIRSDRKEKNAVMSFTVTDEPTFIDLTVSELKEEPVKLAVVCKDGQLHLFEHILNGYCKKPLTSNCTIQIATPGNDGDSTPKPVPILAAAFCTDKQSLLLVYGNTLQPIIEKVSLNTSESHICLIRDVQKALALKTDDAVTKVRTPVVNSDTKVLVPGIPGHSAAVKTPSSGKEKKKSKRKPGETEDSIEERLGALDIDVSKVKTPGGLPQTDSFAVLLVQGLESNDEDILNKVLSTRKETLIKNTVARMPIHAVIPLLHELTKRLQGNPYSASQMVRWLKFVFTLHASYLSTLPDLIPQLGMLYQLMESRVKTLQKLSRLHGRLFLLVTQVAASETVQDVTEVNQTAKLVYEDGKAIR", "length": 608, "header": "tr|A0A8V0Z9U7-1|A0A8V0Z9V2_CHICK Computationally mapped isoform of WD repeat domain 43 OS=Gallus gallus OX=9031 GN=WDR43 PE=1 SV=1 CANONICAL=A0A8V0Z9V2-1" }, "locus": { "chromosome": "3", "start_pos": 8811051, "end_pos": 8789836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042751.1", "url": "https://www.ensembl.org/id/ENSGALT00010042751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025241.1", "url": "https://www.ensembl.org/id/ENSGALP00010025241.1" } ] } }, { "isoform_ac": "A0A8V0Z9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2/entry#A0A8V0Z9V2-1", "sequence": { "sequence": "MAAAAACGGEVAARPPLAFSPHDRRFLAVSGSDGRLRVWDTVGSRLQHEYVPSAHLSAACTCLAWAPPGGRPPPDKDGPQRKKRKSEAAEVDKQLDILAIGTAVGSILLYSTVKGELQSKLDGGHDSRINCVRWHQDNCCLYSCSEDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWDLETKEVYRHFTGHATSVSSLMFTTVKPMNENKPFDGITGLYFLSGAIHDRLLSVWQIRSDRKEKNAVMSFTVTDEPTFIDLTVSELKEEPVKLAVVCKDGQLHLFEHILNGYCKKPLTSNCTIQIATPGNDGDSTPKPVPILAAAFCTDKQSLLLVYGNTLQPIIEKVSLNTSESHICLIRDVQKALALKTDDAVTKVRTPVVNSDTKVLVPGIPGHSAAVKTPSSGKEKKKSKRKPGETEDSIEERLGALDIDVSKVKTPGGLPQTDSFAVLLVQGLESNDEDILNKVLSTRKETLIKNTVARMPIHAVIPLLHELTKRLQGNPYSASQMVRWLKFVFTLHASYLSTLPDLIPQLGMLYQLMESRVKTLQKLSRLHGRLFLLVTQVAASETVQDVTEVNQTAKLVYEDESSEEEGSDDEMIADKDSDENWDEDEEKEEQSDEQDMTVEKEMNGDSDLEPENESEEE", "length": 661, "header": "tr|A0A8V0Z9V2-1|A0A8V0Z9V2_CHICK Isoform 1 of WD repeat domain 43 OS=Gallus gallus OX=9031 GN=WDR43 PE=1 SV=1 CANONICAL=A0A8V0Z9V2-1" }, "locus": { "chromosome": "3", "start_pos": 8811051, "end_pos": 8789760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042756.1", "url": "https://www.ensembl.org/id/ENSGALT00010042756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025246.1", "url": "https://www.ensembl.org/id/ENSGALP00010025246.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421295", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z7K2-1", "protein_name": "Small-subunit processome Utp12 domain-containing protein", "gene_name": "CG2396", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLGKKHVLGFSPNGGQLFASVDESGVLRIWNTETNTLYQEFTPNLQLSGSCTALTWVLVAGSRPKKSRKSLQAQDAAGDQLHIALGTYKGSVVIYSLAEGKISRTLSGDSHDGPVTSITNDNAGHLYTVGADCRVVVWSLTDERSIAEWQVGPEKPQNIVYLQKSGTLAIGYRQLKVYDIKTKELVETFTGHSGEINTISSVASTDGTEFVLTTAKMERVICFWKIDKKGKNKASACTLLMEDLAYCLTSEVRDDGQLRVASVTRNGIIHIYLLNVNSLSAEKFVKPKVSLQIVSDGAETVEPLLAVAAHFVTDSNRSHEILFGYGSRQQLQFERFTPNYGEKLNVIVRADPKKLYAKKKGKEQPGYQAATKVQKPIVNQKNVEYNSALPISQKKVQNEVPMEARLEHLKIQGTKLSGGKLLTQSKTQLLMQALHSKDQAMIQAVLSTQDPETIQLTLDRLPLDYVNPLVNELSILLQGKHASVRSALRWLHALTSTHTSVLMSEDKEALREKLAVCLGVAEQRMHCLSEALQITGRVNLIINQMKRNADNHLNDNKALILDEDPDEPDPEAETNWSDLEEDQPGSPKSPLEDELVADDDLATDDGNADADTDSDVSMD", "length": 620 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1MCK7-1", "protein_name": "WD repeat-containing protein 43", "gene_name": "WDR43", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGGGGVADPLSPAGVPCAFSPQSQAYFALASADGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKEGPQRKKRKSEAIVTSNQADLLALGTAVGSILLYSTVKGELHSKLINGGHDNRVNCIQWHQDNGCLYSCSDDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLTFTTIRPPNEIQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKNAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGNWFQPTIERVALNPKEPHMCLIRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAVKPPPPQTKEVESKRKLGEKEVSIEERLGALDIASKKEKDNLPQTNSFPVLLTQGLESNDFEILNKVLQTRNLNLIKRTVLRMPLHAVIPLLQELTKRLQGHPNSAILMVQWLKCVLTVHASYLSTLPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKETTCPAQKAKLVYEEESSEEESDDEIADKDSDDNWDEDEDEKASEKDEDVDEENEEEEGDDEDKDEENGEDRDVASEKELNGDSDLDPENESEEE", "length": 681 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V920-1", "protein_name": "WD repeat-containing protein 43", "gene_name": "Wdr43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGGGGSCDPLAPAGVPCAFSPDSQAYFALASSDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESHQRKKRKSEAIGTNDQADLLALGTAVGSILLYSTVKGELHSKLISGGHEKRVNCIQWHQDNDCLYSCSDDKYIVEWSTQMCRVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLRFTTIRPNESQPFDGVTGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHVLNGHCKKPLTSNCTIQVATPGKGKKATPKPIPILAAGFCLDKMSLLLVYGSWFQPTIERLALNSKDTHICLERDISNCWAPTVETAITKVKTPVMNSEAKVLVPGVPGHHAPIKLLPAQPKEAENKRKLGGKEATIEERLGAMDLDRRGKKDDLLQTNSFPVLLAQGLESNDFEMLNKVLQTRNVNLIKKTVLRMPLHAVIPLLQELTKRLQGHPNSAVLMVQWLKCVLTIHASYLSTLPDLVHQLGTLYQLMESRVKTFQKLSHLHGKLILLVTQVTASEKTKKMPSPGLKAKLVYEEESSEEESDDEIPEKDSDDNWDEDEEKDSENDEAVDEDSENDEAVDEEDEDREAASEKELNGDSDLDPENESEEE", "length": 674 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LH57-1", "protein_name": "WD repeat-containing protein 43", "gene_name": "WDR43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAGGGGVADPLSPAGVPCAFSPQNQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARSQAKEGPQRKKRKSEAVETSNQDDLLALGTAVGSVLLYSTVRGELHSKLINGGHDNKVNCIQWHQDNGCLYSCSDDKHIVEWNTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKNAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPIIAAGFCSDKMSLLLVYGNWFQPIIERVALNSKEPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPPQREDVENKRKSGKSEVSIEERLGALDIDPKKGKDSLPQTNSFPVLLTQGLESNDFEMLNKVLQTRNLNLIRRTVLRMPLHAVIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLSTLPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLVTQVTASEKTKGTACPPQKAKLVYEEESSEEESDDEIAEKDSDDNWDEDEEEKGSEKDEDVDEENEEEDEDAEEKDEENSEDRDVASEKELNGDSDLDPENESEEE", "length": 681 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15061-1", "protein_name": "WD repeat-containing protein 43", "gene_name": "WDR43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIERVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPPQTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNKVLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLSTLPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE", "length": 677 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQL4-1", "protein_name": "WD repeat-containing protein 43", "gene_name": "Wdr43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGGGGSYDPLAPAGVPCAFSPDSQAYFALASSDGQLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESHQRKKRKSEVTGTKDQADLLALGTAVGSILLYSTVRGELHSKLTSGGHENRVNCIQWHQDNDCLYSCSDDKYIVEWSTQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLRFTTIRPNESQPSDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYVDLTLSENKEEPVKLAVVCRDGQVHLFEHILNGHCKKPLTSNCTIQIATPGKGKKVTPKPIPILAASFCLDKMSLLLVYGNWFQPTIERVALNSKDTHICLERDISNCWAPTVETAITKVKTPVMNSEAKVLVPGIPGHHAPIKLPPAQPKEAENKRKLGSTEATIEERLGAMDLDRKGRKDDLQTNSFAVLLTQGLESNDFEILNKVLQTKNVNLIKRTVLRIPLRVVIPLLQELTKRLQGHPNSAALMIQWLKCVLTIHASYLSTLPDLVEQLGTLYQLMESRVKTFQKLSNLHGKLILLVTQVTASEKSKKMTSPGQKAKLVYEEESSEEESDDEVPEKDSDDNWDEDEDKDSEKDEGVDEDNEEEDEDMEDKEENEEDREVSSEKELNGDSDLDPENESEEE", "length": 677 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T2Q3-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "utp5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSVTTYDKDRELFARVGKDNKIEVFNSFNCKLLHTFVEIEESKNQIILLTFSTHDKSEKKEYYKNLVAVSNSGKIYMYDCIDFKKKGIFDTHSKNITAVVLGKRYLFTSSHGGKVSQWDIKTKHIIRSFESSEKSISSMGLNNRESQLAIANNDITFIDLSNFKESKKVSTGSNSIKQIQFTQDDKFLICNRYQPTIQIYNIEKLTANNTNTTEPTFTLNATSPTKSISIFTHEIKRASKTVTQYLISSLLQNSQINIWAYYQDDQYNTDAETPITEITNKSNQIISMNFHSASELILAFFEKEKYQFERVKFFDKKSFIKSITVENPIEFDKTTTINNKKQKTSETISIQGNAAEMKQDKVNLPTIKKSTDSIASAGTIVDLIAQSLKSDNDNLLLSSIKVNFNVIQSTVKSLPSPYAYSLLSKLLKYLATDNSKSLIVLPWINCIIKDHSSYLLSVPNLSKKLSVLNTIIQDKFELHNRLSKLVGKFELISSQTKGDKTESIDYEPSLVYDEASDNEQQDADGDMVEEDDEDDESDEFDGMEGADDEDDEEIDDDIADLMDDDDDL", "length": 569 }, "evidence": [ { "id": "A0A8V0Z9V2", "url": "https://omabrowser.org/oma/group/A0A8V0Z9V2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "regulation of stem cell population maintenance", "id": "GO:2000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" }, { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V2" }, { "id": "PF04003", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small-subunit processome Utp12", "eco_id": "ECO_0000259", "start_pos": 475, "end_pos": 577, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 594, "end_pos": 596 }, { "start_pos": 656, "end_pos": 658 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAL4-1", "uniprot_ac": "A0A8V0ZAL4", "uniprot_id": "A0A8V0ZAL4_CHICK", "mass": { "chemical_mass": 83310.0, "monoisotopic_mass": 83310.0 }, "refseq": {}, "gene_names": [ { "name": "HHIPL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4" } ] } ], "protein_names": [ { "name": "HHIP like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HHIPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4", "locus": { "chromosome": "3", "start_pos": 17777891, "end_pos": 17761366, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019524", "url": "https://www.ensembl.org/id/ENSGALG00010019524" } ] } } ], "crossref": [ { "id": "A0A8V0ZAL4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9U9", "url": "https://www.orthodb.org/?gene=A0A8V0Z9U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAL4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBC7", "url": "https://www.orthodb.org/?gene=A0A8V0ZBC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPSPLAHQVLCCRQLTDTRNLHKTWICIWSTVGSLLGHPQCLDYGPPFQPPSRLEFCSAYENFGCCDRERDNSIAAKYHEILDYLDPRGHKLCGTYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCFDYCSEFHFNCHSAISLLTSDKHIQDCCETNKTRFCNLLHLHDEDYCFPNVLRNTALNHKLGSVVEDRRGCLQLCLTEVANGLRNPVLMLHANDHTHRMFVAEQVGVIWVYLPDGSRLEEPFLDIKSIVLATPWIGDERGFLGMAFHPNYKNNGKFYIYYSYMDKKKVEKIRISELKVLASDANKADPHSERNLLELEEPAANHNGGQLLFGVDGYLYLFIGDGGKAGDPFGRFGNAQNKSVLLGKVLRIDVDGRSPDGKPYRIPPDNPFVSDPKARPEVYAYGVRNMWRCAVDRGDPVTKKGRGRIFCGDVGQNRFEEVDIIVKGGNYGWRAKEGFECYDTKLCHNSSLDDVLPIFAYGRKVGKSVTGGYVYRGCESPNLNGLYIFGDFMNGRLMALREDEKTNRWKKQDICIGSTKACAFPAMIRSYSKFIISFAEDEAGELYFMSTSYPSAYAPHGSLYKLVDPARRAPPGKCKYKPVTVKIKSKRIAFVPRAKTVLEFLNEPPPTKPPKRSSTLPGAAPTAAAKKSKKMASSKVKASTVKPALSNKKTPKTKAGGEHHRPKQKGARVPRTTPAPSLARRKSSQLTGAKKLLTEKAAQAKGTPGRRRKESR", "length": 744, "header": "tr|A0A8V0ZAL4-1|A0A8V0ZAL4_CHICK Isoform 1 of HHIP like 2 OS=Gallus gallus OX=9031 GN=HHIPL2 PE=4 SV=1 CANONICAL=A0A8V0ZAL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4/entry#A0A8V0Z9U9-1", "sequence": { "sequence": "MFGQALAGEGAALELPFLARMSFFVSPCSAYENFGCCDRERDNSIAAKYHEILDYLDPRGHKLCGTYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCFDYCSEFHFNCHSAISLLTSDKHIQDCCETNKTRFCNLLMLHANDHTHRMFVAEQVGVIWVYLPDGSRLEEPFLDIKSIVLATPWIGDERGFLGMAFHPNYKNNGKFYIYYSYMDKKKVEKIRISELKVLASDANKADPHSERNLLELEEPAANHNGGQLLFGVDGYLYLFIGDGGKAGDPFGRFGNAQNKSVLLGKVLRIDVDGRSPDGKPYRIPPDNPFVSDPKARPEVYAYGVRNMWRCAVDRGDPVTKKGRGRIFCGDVGQNRFEEVDIIVKGGNYGWRAKEGFECYDTKLCHNSSLDDVLPIFAYGRKVGKSVTGGYVYRGCESPNLNGLYIFGDFMNGRLMALREDEKTNRWKKQDICIGSTKACAFPAMIRSYSKFIISFAEDEAGELYFMSTSYPSAYAPHGSLYKLVDPARRAPPGKCKYKPVTVKIKSKRIAFVPRAKTVLEFLNEPPPTKPPKRSSTLPGAAPTAAAKKSKKMASSKVKASTVKPALSNKKTPKTKAGGEHHRPKQKGARVPRTTPAPSLARRKSSQLTGAKKLLTEKAAQAKGTPGRRRKESR", "length": 665, "header": "tr|A0A8V0Z9U9-1|A0A8V0ZAL4_CHICK Computationally mapped isoform of HHIP like 2 OS=Gallus gallus OX=9031 GN=HHIPL2 PE=4 SV=1 CANONICAL=A0A8V0ZAL4-1" }, "locus": { "chromosome": "3", "start_pos": 17777726, "end_pos": 17762908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047126.1", "url": "https://www.ensembl.org/id/ENSGALT00010047126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027959.1", "url": "https://www.ensembl.org/id/ENSGALP00010027959.1" } ] } }, { "isoform_ac": "A0A8V0ZAL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4/entry#A0A8V0ZAL4-1", "sequence": { "sequence": "MSPSPLAHQVLCCRQLTDTRNLHKTWICIWSTVGSLLGHPQCLDYGPPFQPPSRLEFCSAYENFGCCDRERDNSIAAKYHEILDYLDPRGHKLCGTYIKDILCQECSPYAAHLYDAENPRTPLRNLPGLCFDYCSEFHFNCHSAISLLTSDKHIQDCCETNKTRFCNLLHLHDEDYCFPNVLRNTALNHKLGSVVEDRRGCLQLCLTEVANGLRNPVLMLHANDHTHRMFVAEQVGVIWVYLPDGSRLEEPFLDIKSIVLATPWIGDERGFLGMAFHPNYKNNGKFYIYYSYMDKKKVEKIRISELKVLASDANKADPHSERNLLELEEPAANHNGGQLLFGVDGYLYLFIGDGGKAGDPFGRFGNAQNKSVLLGKVLRIDVDGRSPDGKPYRIPPDNPFVSDPKARPEVYAYGVRNMWRCAVDRGDPVTKKGRGRIFCGDVGQNRFEEVDIIVKGGNYGWRAKEGFECYDTKLCHNSSLDDVLPIFAYGRKVGKSVTGGYVYRGCESPNLNGLYIFGDFMNGRLMALREDEKTNRWKKQDICIGSTKACAFPAMIRSYSKFIISFAEDEAGELYFMSTSYPSAYAPHGSLYKLVDPARRAPPGKCKYKPVTVKIKSKRIAFVPRAKTVLEFLNEPPPTKPPKRSSTLPGAAPTAAAKKSKKMASSKVKASTVKPALSNKKTPKTKAGGEHHRPKQKGARVPRTTPAPSLARRKSSQLTGAKKLLTEKAAQAKGTPGRRRKESR", "length": 744, "header": "tr|A0A8V0ZAL4-1|A0A8V0ZAL4_CHICK Isoform 1 of HHIP like 2 OS=Gallus gallus OX=9031 GN=HHIPL2 PE=4 SV=1 CANONICAL=A0A8V0ZAL4-1" }, "locus": { "chromosome": "3", "start_pos": 17777726, "end_pos": 17761410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047134.1", "url": "https://www.ensembl.org/id/ENSGALT00010047134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027961.1", "url": "https://www.ensembl.org/id/ENSGALP00010027961.1" } ] } }, { "isoform_ac": "A0A8V0ZBC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4/entry#A0A8V0ZBC7-1", "sequence": { "sequence": "MNEPEVQGFHTSDLRKSTLKKVNVWPGTGRRRSSSRASFSCPHVFLCFSLFCWIGSLLGHPQCLDYGPPFQPPSRLEFCSAYENFGCCDRERDNSIAAKYHEILDYLDPRGHKLCGTYIKDILCQNLLELEEPAANHNGGQLLFGVDGYLYLFIGDGGKAGDPFGRFGNAQNKSVLLGKVLRIDVDGRSPDGKPYRIPPDNPFVSDPKARPEVYAYGVRNMWRCAVDRGDPVTKKGRGRIFCGDVGQNRFEEVDIIVKGGNYGWRAKEGFECYDTKLCHNSSLDDVLPIFAYGRKVGKSVTGGYVYRGCESPNLNGLYIFGDFMNGRLMALREDEKTNRWKKQDICIGSTKACAFPAMIRSYSKFIISFAEDEAGELYFMSTSYPSAYAPHGSLYKLVDPARRAPPGKCKYKPVTVKIKSKRIAFVPRAKTVLEFLNEPPPTKPPKRSSTLPGAAPTAAAKKSKKMASSKVKASTVKPALSNKKTPKTKAGGEHHRPKQKGARVPRTTPAPSLARRKSSQLTGAKKLLTEKAAQAKGTPGRRRKESR", "length": 547, "header": "tr|A0A8V0ZBC7-1|A0A8V0ZBC7_CHICK Computationally mapped isoform of HHIP like 2 OS=Gallus gallus OX=9031 GN=HHIPL2 PE=4 SV=1 CANONICAL=A0A8V0ZAL4-1" }, "locus": { "chromosome": "3", "start_pos": 17777726, "end_pos": 17762841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047131.1", "url": "https://www.ensembl.org/id/ENSGALT00010047131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027960.1", "url": "https://www.ensembl.org/id/ENSGALP00010027960.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 654, "start_aa": "Thr", "end_pos": 654, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr654", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL4" }, { "id": "PF07995", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glucose/Sorbosone dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 541, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 654 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 477, "end_pos": 479 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9W0-1", "uniprot_ac": "A0A8V0Z9W0", "uniprot_id": "A0A8V0Z9W0_CHICK", "mass": { "chemical_mass": 15389.0, "monoisotopic_mass": 15389.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9W0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9W0", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z9W0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AKDLRDGEGCVDVFPPLAGLGDEQHREHPDAHTDKLHPVPLLGGSAGGVDDGQVAVHTDASQQQDAAVEVGFLQHRDGFAHDGAKNPLVGPVDGPERQAEGKEQVGHSQVEQITTWGHRVPPGSGVPYVDLGLRYAELSLHPLPR", "length": 145, "header": "tr|A0A8V0Z9W0-1|A0A8V0Z9W0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9W0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W0/entry#A0A8V0Z9W0-1", "sequence": { "sequence": "AKDLRDGEGCVDVFPPLAGLGDEQHREHPDAHTDKLHPVPLLGGSAGGVDDGQVAVHTDASQQQDAAVEVGFLQHRDGFAHDGAKNPLVGPVDGPERQAEGKEQVGHSQVEQITTWGHRVPPGSGVPYVDLGLRYAELSLHPLPR", "length": 145, "header": "tr|A0A8V0Z9W0-1|A0A8V0Z9W0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z9W0-1" }, "locus": { "chromosome": "7", "start_pos": 22213120, "end_pos": 22211655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046547.1", "url": "https://www.ensembl.org/id/ENSGALT00010046547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027712.1", "url": "https://www.ensembl.org/id/ENSGALP00010027712.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9W2-1", "uniprot_ac": "A0A8V0Z9W2", "uniprot_id": "A0A8V0Z9W2_CHICK", "mass": { "chemical_mass": 188038.0, "monoisotopic_mass": 188038.0 }, "refseq": {}, "gene_names": [ { "name": "PRDM2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.355", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#names_and_taxonomy" } ] }, { "name": "PR domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#names_and_taxonomy" } ] }, { "name": "Retinoblastoma protein-interacting zinc finger protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein RIZ", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM9#function" }, { "database": "UniProtKB", "id": "ARBA00058611", "url": "https://www.uniprot.org/uniprotkb/ARBA00058611#function" }, { "database": "UniProtKB", "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRDM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2", "locus": { "chromosome": "21", "start_pos": 5107069, "end_pos": 5170656, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021029", "url": "https://www.ensembl.org/id/ENSGALG00010021029" } ] } } ], "crossref": [ { "id": "cd19188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9W2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFM9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGX9", "url": "https://www.orthodb.org/?gene=A0A8V0ZGX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN14", "url": "https://www.orthodb.org/?gene=A0A8V0ZN14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "60276", "url": "https://www.rhea-db.org/rhea/60276", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQNTTEPPAVVETLADVPEHVLRGLPEDVRLFPSAVDKTRLGVWATKSILKGKKFGPFVGDKKKRSQVKSNVYMWEVYYPNLGWMCVDATDPKKGNWLRYINWARSGKEQNLFPLEINRTIYYKSLKPIAPGEELLVWYNGEDDPEIAAAIEEERASARSRRHSPKAKKGKKKTQESKNKGRKATDTKQKKTDLDSSADMRDSKEGHKEEDEKPSVSAVLSLEQTAVIQEMVNQDVLPKLMIPSPASELQIVTEEKQEEAINCASDDLDEDEEEDEEEEEEEMEDTNMPKENAEMPLICEEKLDSMEEQKSTSEESPESSPKKLVVKIPKARGESNGDVQETFMFPCQHCERKFTTKQGLERHMHIHISTVNHAFKCRYCGKAFGTQINRRRHERRHEAGPKRKPFLTLTSSQHLDNVADNQVIVSDGLKDDLNVSNLVQDSVVLDSEKVSQEMSHSAFAEENKEPKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGYFHEEPPLQTEQAPPVQSVYIASTEIEEEGEIDDVYIMDISSNISENLNYYIDGKIQSNSSTSNCDVIQMESNSADLYGLNCIISPVTVEISSNIKITQTQVNEPPKEPSVSGSNESKKRRTASPPLVPKIKTEIEPEPITPTSSLSLPLSISTEGLPFHKDKSVYLSSKLKQLLQTQDSKKITPSSEIPKLGPSVASSSILPPVSSRFKRRTSSPPSSPQHSPVLRDFVKSGEGKTVWNDSLRSSKMPKLESHSNSPAWSLTGREERETVSPLCFEDFKTSKDWTVAPTFGNVCNQQPLDLSSGVKQRSDIKNKHQVPWESVLDLSVHKKPCSDAEVREYRENSIQPTCSGVKKKKPTTCMLQKVLLNEYNGMDAATDSAPSVNRSPSPSKSLESQAEPDTDPSLSASSSVDTQPLSSSVSLVPHTSVVPSMCQLPPLLTPTNPPSPPPCPPVLTVATSPPPLLPTMPLSIPDVSASATNTSSCPSPLSNTTTQSPLPVLSPTVSPSPSPVPSVEPLISAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSVVSSVVSSADNLENTLPIIKQEETENEQKAREDPRTASESGVVQETFNKSFVCNVCESPFLSIKDLTKHLSVHAEEWPFKCEFCVQLFRDKTGLSEHRFLLHGVGNIFACSVCKKEFAFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKANIEHMQSLSEDSLELSKEEEEDEDLNDSSEELYTTIKIMASGVKSKDPDVRMGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKSVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGMVVITGPGKNAFRRMGQPKRLNFNVEISKMSSNKLKINALKKKNQLVQKAILQKKKSAQQKAELKNSLSESDSHICPYCNREFTYIGSLNKHASYSCPKKPISPSSKKKSSKKGASSSPANSERGSNQRRRTADAEIKLQSMQPHLGKTRARTSGPAQIQLPSASFKSKQNIKFVPPIRSKRPNPSSSLRNSSPVRVSKMTHVDGKKTKVVGKNTSSGISSKATRKLHVRIQRSNKAVLPSRSAVASKKKADRFTVKSRERIGGPITRSLQQAANAEAAENKKDESSTKQELKDFSYRLRMASRCPSSSSNTSTRQCKKSSCTASPFFKE", "length": 1696, "header": "tr|A0A8V0Z9W2-1|A0A8V0Z9W2_CHICK Isoform 1 of PR domain zinc finger protein 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#A0A8V0Z9W2-1", "sequence": { "sequence": "MNQNTTEPPAVVETLADVPEHVLRGLPEDVRLFPSAVDKTRLGVWATKSILKGKKFGPFVGDKKKRSQVKSNVYMWEVYYPNLGWMCVDATDPKKGNWLRYINWARSGKEQNLFPLEINRTIYYKSLKPIAPGEELLVWYNGEDDPEIAAAIEEERASARSRRHSPKAKKGKKKTQESKNKGRKATDTKQKKTDLDSSADMRDSKEGHKEEDEKPSVSAVLSLEQTAVIQEMVNQDVLPKLMIPSPASELQIVTEEKQEEAINCASDDLDEDEEEDEEEEEEEMEDTNMPKENAEMPLICEEKLDSMEEQKSTSEESPESSPKKLVVKIPKARGESNGDVQETFMFPCQHCERKFTTKQGLERHMHIHISTVNHAFKCRYCGKAFGTQINRRRHERRHEAGPKRKPFLTLTSSQHLDNVADNQVIVSDGLKDDLNVSNLVQDSVVLDSEKVSQEMSHSAFAEENKEPKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGYFHEEPPLQTEQAPPVQSVYIASTEIEEEGEIDDVYIMDISSNISENLNYYIDGKIQSNSSTSNCDVIQMESNSADLYGLNCIISPVTVEISSNIKITQTQVNEPPKEPSVSGSNESKKRRTASPPLVPKIKTEIEPEPITPTSSLSLPLSISTEGLPFHKDKSVYLSSKLKQLLQTQDSKKITPSSEIPKLGPSVASSSILPPVSSRFKRRTSSPPSSPQHSPVLRDFVKSGEGKTVWNDSLRSSKMPKLESHSNSPAWSLTGREERETVSPLCFEDFKTSKDWTVAPTFGNVCNQQPLDLSSGVKQRSDIKNKHQVPWESVLDLSVHKKPCSDAEVREYRENSIQPTCSGVKKKKPTTCMLQKVLLNEYNGMDAATDSAPSVNRSPSPSKSLESQAEPDTDPSLSASSSVDTQPLSSSVSLVPHTSVVPSMCQLPPLLTPTNPPSPPPCPPVLTVATSPPPLLPTMPLSIPDVSASATNTSSCPSPLSNTTTQSPLPVLSPTVSPSPSPVPSVEPLISAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSVVSSVVSSADNLENTLPIIKQEETENEQKAREDPRTASESGVVQETFNKSFVCNVCESPFLSIKDLTKHLSVHAEEWPFKCEFCVQLFRDKTGLSEHRFLLHGVGNIFACSVCKKEFAFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKANIEHMQSLSEDSLELSKEEEEDEDLNDSSEELYTTIKIMASGVKSKDPDVRMGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKSVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGMVVITGPGKNAFRRMGQPKRLNFNVEISKMSSNKLKINALKKKNQLVQKAILQKKKSAQQKAELKNSLSESDSHICPYCNREFTYIGSLNKHASYSCPKKPISPSSKKKSSKKGASSSPANSERGSNQRRRTADAEIKLQSMQPHLGKTRARTSGPAQIQLPSASFKSKQNIKFVPPIRSKRPNPSSSLRNSSPVRVSKMTHVDGKKTKVVGKNTSSGISSKATRKLHVRIQRSNKAVLPSRSAVASKKKADRFTVKSRERIGGPITRSLQQAANAEAAENKKDESSTKQELKDFSYRLRMASRCPSSSSNTSTRQCKKSSCTASPFFKE", "length": 1696, "header": "tr|A0A8V0Z9W2-1|A0A8V0Z9W2_CHICK Isoform 1 of PR domain zinc finger protein 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "locus": { "chromosome": "21", "start_pos": 5163988, "end_pos": 5112486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050882.1", "url": "https://www.ensembl.org/id/ENSGALT00010050882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030073.1", "url": "https://www.ensembl.org/id/ENSGALP00010030073.1" } ] } }, { "isoform_ac": "A0A8V0ZFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#A0A8V0ZFM9-1", "sequence": { "sequence": "MNQNTTEPPAVVETLADVPEHVLRGLPEDVRLFPSAVDKTRLGVWATKSILKGKKFGPFVGDKKKRSQVKSNVYMWEVYYPNLGWMCVDATDPKKGNWLRYINWARSGKEQNLFPLEINRTIYYKSLKPIAPGEELLVWYNGEDDPEIAAAIEEERASARSRRHSPKAKKGKKKTQESKNKGRKATDTKQKKTDLDSSADMRDSKEGHKEEDEKPSVSAVLSLEQTAVIQEMVNQDVLPKLMIPSPASELQIVTEEKQEEAINCASDDLDEDEEEDEEEEEEEMEDTNMPKENAEMPLICEEKLDSMEEQKSTSEESPESSPKKLVVKIPKARGESNGDVQETFMFPCQHCERKFTTKQGLERHMHIHISTVNHAFKCRYCGKAFGTQINRRRHERRHEAGPKRKPFLTLTSSQHLDNVADNQVIVSDGLKDDLNVSNLVQDSVVLDSEKVSQEMSHSAFAEENKEPKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGYFHEEPPLQTEQAPPVQSVYIASTEIEEEGEIDDVYIMDISSNISENLNYYIDGKIQSNSSTSNCDVIQMESNSADLYGLNCIISPVTVEISSNIKITQTQVNEPPKEPSVSGSNESKKRRTASPPLVPKIKTEIEPEPITPTSSLSLPLSISTEGLPFHKDKSVYLSSKLKQLLQTQDSKKITPSSEIPKLGPSVASSSILPPVSSRFKRRTSSPPSSPQHSPVLRDFVKSGEGKTVWNDSLRSSKMPKLESHSNSPAWSLTGREERETVSPLCFEDFKTSKDWTVAPTFGNVCNQQPLDLSSGVKQRSDIKNKHQVPWESVLDLSVHKKPCSDAEVREYRENSIQPTCSGVKKKKPTTCMLQKVLLNEYNGMDAATDSAPSVNRSPSPSKSLESQAEPDTDPSLSASSSVDTQPLSSSVSLVPHTSVVPSMCQLPPLLTPTNPPSPPPCPPVLTVATSPPPLLPTMPLSIPDVSASATNTSSCPSPLSNTTTQSPLPVLSPTVSPSPSPVPSVEPLISAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSVVSSVVSSADNLENTLPIIKQEETENEQKAREDPRTASESGVVQETFNKSFVCNVCESPFLSIKDLTKHLSVHAEEWPFKCEFCVQLFRDKTGLSEHRFLLHGVGNIFACSVCKKEFAFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKANIEHMQSLSEDSLELSKEEEEDEDLNDSSEELYTTIKIMASGVKSKDPDVRMGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKSVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGMVVITGPGKNAFRRMGQPKRLNFNVEISKMSSNKLKINALKKKNQLVQKAILQKKKSAQQKAELKNSLSESDSHICPYCNREFTYIGSLNKHASYSCPKKPISPSSKKKSSKKGASSSPANSERGSNQRRRTADAEIKLQSMQPHLGKTRARTSGPAQIQLPSASFKSKQNIKFVPPIRSKRPNPSSSLRNSSPVRVSKMTHVDGKKTKVVGKNTSSGISSKATRKLHVRIQRSNKAVLPSRSAVASKKKADRFTVKSRERIGGPITRSLQQAANAEAAENKKDESSTKQELKDFRNIQ", "length": 1665, "header": "tr|A0A8V0ZFM9-1|A0A8V0ZFM9_CHICK Computationally mapped isoform of PR domain zinc finger protein 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "locus": { "chromosome": "21", "start_pos": 5163988, "end_pos": 5121353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050879.1", "url": "https://www.ensembl.org/id/ENSGALT00010050879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030070.1", "url": "https://www.ensembl.org/id/ENSGALP00010030070.1" } ] } }, { "isoform_ac": "A0A8V0ZFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#A0A8V0ZFN4-1", "sequence": { "sequence": "MNQNTTEPPAVVETLADVPEHVLRGLPEDVRLFPSAVDKTRLGVWATKSILKGKKFGPFVGDKKKRSQVKSNVYMWEVYYPNLGWMCVDATDPKKGNWLRYINWARSGKEQNLFPLEINRTIYYKSLKPIAPGEELLVWYNGEDDPEIAAAIEEERASARSRRHSPKAKKVTGSAWPLDVPPLLLTPAPGNARNPAALHPPSSRNRPLRVRAEQVQNFWLEKERGSNPAASSQLR", "length": 235, "header": "tr|A0A8V0ZFN4-1|A0A8V0ZFN4_CHICK Computationally mapped isoform of PR/SET domain 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "locus": { "chromosome": "21", "start_pos": 5163988, "end_pos": 5111269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050884.1", "url": "https://www.ensembl.org/id/ENSGALT00010050884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030075.1", "url": "https://www.ensembl.org/id/ENSGALP00010030075.1" } ] } }, { "isoform_ac": "A0A8V0ZGW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#A0A8V0ZGW3-1", "sequence": { "sequence": 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PR/SET domain 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "locus": { "chromosome": "21", "start_pos": 5163988, "end_pos": 5111274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050892.1", "url": "https://www.ensembl.org/id/ENSGALT00010050892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030083.1", "url": "https://www.ensembl.org/id/ENSGALP00010030083.1" } ] } }, { "isoform_ac": "A0A8V0ZN14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2/entry#A0A8V0ZN14-1", "sequence": { "sequence": "MNQNTTEPPAVVETLADVPEHVLRGLPEDVRLFPSAVDKTRLGVWATKSILKGKKFGPFVGDKKKRSQVKSNVYMWEVYYPNLGWMCVDATDPKKGNWLRYINWARSGKEQNLFPLEINRTIYYKSLKPIAPGEELLVWYNGEDDPEIAAAIEEERASARSRRHSPKAKKDQVEDPAGRSSHVGPFRNLMVSARVYLYSGFHQVLYCEELFSLLQASVSP", "length": 220, "header": "tr|A0A8V0ZN14-1|A0A8V0ZN14_CHICK Computationally mapped isoform of PR/SET domain 2 OS=Gallus gallus OX=9031 GN=PRDM2 PE=4 SV=1 CANONICAL=A0A8V0Z9W2-1" }, "locus": { "chromosome": "21", "start_pos": 5163988, "end_pos": 5132415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050878.1", "url": "https://www.ensembl.org/id/ENSGALT00010050878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030069.1", "url": "https://www.ensembl.org/id/ENSGALP00010030069.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 648, "start_aa": "Thr", "end_pos": 648, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr648", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": 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8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLTLVRSFVQPLLAAMRHSLVYHTPPAAHLKPSASRPQQQKKLVRPKRHSSRNRRETSEKRAPHGTYGHPAASCLVVQRQEMTAFFKLFDDDLIQDFLWMDCCCKIADKYLLAMTFVYFKRANFTVDEHTRLNFFVALYLANTVEEDNEESKYEIFPWALGKNWRKLFPDFLKLRDHLWSRIDYRAIVSRRCCEEVMAIAPTHYIWQRERSVYHSGAIRNYNKDEAQLPRGPNNSPIPCYLCGKKGRFVRLGLSSSSSSSTGSLEVTELCSSQDLKGTFAIEKMLVDSPASSAQDCQSLSSKRRRDNTSNQDKSMDWFTSNEE", "length": 325, "header": "tr|A0A8V0Z9W4-1|A0A8V0Z9W4_CHICK Isoform 1 of Speedy/RINGO cell cycle regulator family member A OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z9W4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W4/entry#A0A8V0Z9W4-1", "sequence": { "sequence": "MSVLTLVRSFVQPLLAAMRHSLVYHTPPAAHLKPSASRPQQQKKLVRPKRHSSRNRRETSEKRAPHGTYGHPAASCLVVQRQEMTAFFKLFDDDLIQDFLWMDCCCKIADKYLLAMTFVYFKRANFTVDEHTRLNFFVALYLANTVEEDNEESKYEIFPWALGKNWRKLFPDFLKLRDHLWSRIDYRAIVSRRCCEEVMAIAPTHYIWQRERSVYHSGAIRNYNKDEAQLPRGPNNSPIPCYLCGKKGRFVRLGLSSSSSSSTGSLEVTELCSSQDLKGTFAIEKMLVDSPASSAQDCQSLSSKRRRDNTSNQDKSMDWFTSNEE", "length": 325, "header": "tr|A0A8V0Z9W4-1|A0A8V0Z9W4_CHICK Isoform 1 of Speedy/RINGO cell cycle regulator family member A OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0Z9W4-1" }, "locus": { "chromosome": "3", "start_pos": 8822298, "end_pos": 8817455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042766.1", "url": "https://www.ensembl.org/id/ENSGALT00010042766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025256.1", "url": "https://www.ensembl.org/id/ENSGALP00010025256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": 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[ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W4" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"evidence": [ { "id": "XP_428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428882" } ] } ], "protein_names": [ { "name": "Leucine zipper tumor suppressor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper putative tumor suppressor 1", "type": "synonym", "evidence": [ { "id": "XP_428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428882" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_428882.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_428882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428882" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LZTS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7", "locus": { "chromosome": "22", "start_pos": 1748942, "end_pos": 1736251, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017691", "url": "https://www.ensembl.org/id/ENSGALG00010017691" } ] } } ], "crossref": [ { "id": "A0A8V0Z9W7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9W7", "database": "AlphaFoldDB", "categories": [] }, { "id": "431331", "url": "https://www.ncbi.nlm.nih.gov/gene/431331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR045329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431331", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431331", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKTRGSH", "url": "https://omabrowser.org/oma/group/QKTRGSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9W7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19354:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19354:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_428882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQESGHKSGSKSSKNEDFFYIKVSQKAPGPHRTDYTALGSTELGQAGSSGVDFGTPTPQKLMPFPSQLEVGVEKPMARPTAFKPVLPRSGAVLHSSPENGAHLPTQLHPLDKGKEQELKPVLCSGGLSDSGRNSMSSLPTHSTSSSYQLDPIVTPVGPISRFGGSAHNIMQCAIIQDSNMMSLKAMSFSDGGNKILNPGKAPQHRAAEKTACIRSPISTDESTIQELEQKLLEREGELQELQLSFEEKEASSCQVYEEKQRRCKEELEGLKQRCNSKLKQSSQKTQRTQQVLQLQVFQLQQEKQQLREELENLMKEQNLLETKLRSYEKEKTSFAPALEETQWEVCQKSGEISLLKQQLKESQTELTTKTTEILSLKAQLKDVRAKMEGLEMKTQDLEGSLRTKAMELEVCENELQRKKNESELLREKVNLLEQEIVELRAEMAVLRAQLSDATRPSEVQALQGEVERLRAELQAERDSNEQMSSSFQQERQTWREEKEKVIHYQKQLQQSYLHMYKRNQNLEKMLQQLAAGEDGKEPIELDIPGADVPYEDIIATEI", "length": 604, "header": "tr|A0A8V0Z9W7-1|A0A8V0Z9W7_CHICK Isoform 1 of Leucine zipper tumor suppressor 1 OS=Gallus gallus OX=9031 GN=LZTS1 PE=4 SV=1 CANONICAL=A0A8V0Z9W7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7/entry#A0A8V0Z9W7-1", "sequence": { "sequence": "MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQESGHKSGSKSSKNEDFFYIKVSQKAPGPHRTDYTALGSTELGQAGSSGVDFGTPTPQKLMPFPSQLEVGVEKPMARPTAFKPVLPRSGAVLHSSPENGAHLPTQLHPLDKGKEQELKPVLCSGGLSDSGRNSMSSLPTHSTSSSYQLDPIVTPVGPISRFGGSAHNIMQCAIIQDSNMMSLKAMSFSDGGNKILNPGKAPQHRAAEKTACIRSPISTDESTIQELEQKLLEREGELQELQLSFEEKEASSCQVYEEKQRRCKEELEGLKQRCNSKLKQSSQKTQRTQQVLQLQVFQLQQEKQQLREELENLMKEQNLLETKLRSYEKEKTSFAPALEETQWEVCQKSGEISLLKQQLKESQTELTTKTTEILSLKAQLKDVRAKMEGLEMKTQDLEGSLRTKAMELEVCENELQRKKNESELLREKVNLLEQEIVELRAEMAVLRAQLSDATRPSEVQALQGEVERLRAELQAERDSNEQMSSSFQQERQTWREEKEKVIHYQKQLQQSYLHMYKRNQNLEKMLQQLAAGEDGKEPIELDIPGADVPYEDIIATEI", "length": 604, "header": "tr|A0A8V0Z9W7-1|A0A8V0Z9W7_CHICK Isoform 1 of Leucine zipper tumor suppressor 1 OS=Gallus gallus OX=9031 GN=LZTS1 PE=4 SV=1 CANONICAL=A0A8V0Z9W7-1" }, "locus": { "chromosome": "22", "start_pos": 1747706, "end_pos": 1745490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042771.1", "url": "https://www.ensembl.org/id/ENSGALT00010042771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025261.1", "url": "https://www.ensembl.org/id/ENSGALP00010025261.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431331", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431331", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BHA0-1", "protein_name": "Leucine zipper tumor suppressor 1", "gene_name": "LZTS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSVSSLISGHGFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGHGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDLGGQAGVDFDPSTPPKLMPFSNQLEMGSEKGAVRPTAFKPVLPRSGAILHSSPESAGHQLHPAPLDKPKEQELKPSLCSGALSDSGRNSMSSLPTHSTSSSYQLDPLVTPVGPASRFGGSAHNITQGIVLQDSNMMSLKALSFSDGGSKLAHASKDKGSVRSPISTDQCTIQELEKQLLEREGELQRLHRSFEEKELAASQPYEERPRRCKDELEGLEAKGKMKVAAQKSQRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEKEKTSFAPALEETQWEVCQKSGEISLLKQQLKESQTEINAKASEILNLKAQLKDTRGRLESLELKTQDLENALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELLELRAQAALQRSRDAAALGPASADDVPALQRELERLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQRLEKALQQLARGDGAGEPFEIDLEGADIPYEDIIATEI", "length": 595 }, "evidence": [ { "id": "A0A8V0Z9W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9W7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H6W2-1", "protein_name": "Leucine zipper putative tumor suppressor 1", "gene_name": "Lzts1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLKFGFSQDSGRGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDMGGQAGVDFDPATPPKLMPFSNQLEMSSDKGAVRPTAFKPVLPRSGAILHSSPESASHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKVDKGSSCVRSPLSTDECTIQELEQKLLQRESALQKLQRSFDEKEFVSGQTFEERPRRTRDELECLEPKSKLKPASQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQKSGEISLLKQQLKESQIEVNTKASEILSLKAQLKDTRGKLESMELKTQDLESALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELLELRAQAALHREATSLGPLGVGPTFSEDIPALQRELERLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQRLEKALQQLARGDGAVEPFEIDLEGADIPYEDIIATEI", "length": 601 }, "evidence": [ { "id": "A0A8V0Z9W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9W7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P60853-1", "protein_name": "Leucine zipper putative tumor suppressor 1", "gene_name": "Lzts1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDIGGQTGVDFDPATPPKLMPFSNQLEMSSDKGAVRPTAFKPVLPRSGAILHSSPESTSHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKADKGASCVRSPLSTDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQTFEERPRRTRDELECLEPKSKLKPPSQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQKSGEISLLKQQLKESQLEVNTKASEILSLKAQLKDTRGKLDGMELKTQDLESALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELMELRAQAALHPAPLGPPGVGLTFSEDIPALQRELDRLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQRQLQQSYLAMYQRNQRLEKALQQLARGDGPGEPFEIDLEGADIPYEDIIATEI", "length": 599 }, "evidence": [ { "id": "A0A8V0Z9W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9W7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CFC9-1", "protein_name": "Leucine zipper putative tumor suppressor 1", "gene_name": "Lzts1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSVSSLISGHSLHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDMGGQTGVDFDPATPPKLMPFSSQLEMSSDKAAVRPTAFKPVLPRSGAILHSSPESTNHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKVEKGSSCVRSPLSTDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQTFEERPRRTRDELECLEPKSKLKPASQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQKSGEISLLKQQLKESQMEVNAKASEILSLKAQLKDTRGKLEGMELKTQDLESALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELLELRAQAALHRDAAPLGPPGIGLTFSEDIPALQRELDRLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQRLEKALQQLARGDIAGEPFEIDLEGADIPYEDIIATEI", "length": 601 }, "evidence": [ { "id": "A0A8V0Z9W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9W7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y250-1", "protein_name": "Leucine zipper putative tumor suppressor 1", "gene_name": "LZTS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGHGKSSSKMGKSEDFFYIKVSQKARGSHHPDYTALSSGDLGGQAGVDFDPSTPPKLMPFSNQLEMGSEKGAVRPTAFKPVLPRSGAILHSSPESASHQLHPAPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTSSSYQLDPLVTPVGPTSRFGGSAHNITQGIVLQDSNMMSLKALSFSDGGSKLGHSNKADKGPSCVRSPISTDECSIQELEQKLLEREGALQKLQRSFEEKELASSLAYEERPRRCRDELEGPEPKGGNKLKQASQKSQRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGPALEETQWEVCQKSGEISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLRAELREERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQRLEKALQQLARGDSAGEPLEVDLEGADIPYEDIIATEI", "length": 596 }, "evidence": [ { "id": "A0A8V0Z9W7", "url": "https://omabrowser.org/oma/group/A0A8V0Z9W7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" }, { "name": "negative regulation of macroautophagy", "id": "GO:0016242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9W7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 466, "end_pos": 468 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9X6-1", "uniprot_ac": "A0A8V0Z9X6", "uniprot_id": "A0A8V0Z9X6_CHICK", "mass": { "chemical_mass": 22449.0, "monoisotopic_mass": 22449.0 }, "refseq": {}, "gene_names": [ { "name": "LOC415324", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6" } ] } ], "protein_names": [ { "name": "LRAT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC415324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z9X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9X0", "url": "https://www.orthodb.org/?gene=A0A8V0Z9X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9X6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGX4", "url": "https://www.orthodb.org/?gene=A0A8V0ZGX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLEQVSSLLRTLQDKVPTFLQPQYWLRSWMWQVWMELIKAAQVSSSKQAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGHPLHNTGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 208, "header": "tr|A0A8V0Z9X6-1|A0A8V0Z9X6_CHICK Isoform 1 of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0Z9X0-1", "sequence": { "sequence": "MAPALFVLSVSSLLRTLQDKVPTFLQPQYWLRSWMWQVSSSKQVMAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 194, "header": "tr|A0A8V0Z9X0-1|A0A8V0Z9X6_CHICK Computationally mapped isoform of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1420803, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050894.1", "url": "https://www.ensembl.org/id/ENSGALT00010050894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030084.1", "url": "https://www.ensembl.org/id/ENSGALP00010030084.1" } ] } }, { "isoform_ac": "A0A8V0Z9X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0Z9X6-1", "sequence": { "sequence": "MDLLEQVSSLLRTLQDKVPTFLQPQYWLRSWMWQVWMELIKAAQVSSSKQAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGHPLHNTGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 208, "header": "tr|A0A8V0Z9X6-1|A0A8V0Z9X6_CHICK Isoform 1 of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1420882, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050898.1", "url": "https://www.ensembl.org/id/ENSGALT00010050898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030089.1", "url": "https://www.ensembl.org/id/ENSGALP00010030089.1" } ] } }, { "isoform_ac": "A0A8V0ZFP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0ZFP4-1", "sequence": { "sequence": "MAPALFVLSAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 160, "header": "tr|A0A8V0ZFP4-1|A0A8V0ZFP4_CHICK Computationally mapped isoform of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1420803, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050895.1", "url": "https://www.ensembl.org/id/ENSGALT00010050895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030086.1", "url": "https://www.ensembl.org/id/ENSGALP00010030086.1" } ] } }, { "isoform_ac": "A0A8V0ZFP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0ZFP7-1", "sequence": { "sequence": "GRDSLGTFLGAGTASDLGSCSLGTAEQQGNIKGVSKVSSSKQAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 193, "header": "tr|A0A8V0ZFP7-1|A0A8V0ZFP7_CHICK Computationally mapped isoform of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1421151, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050900.1", "url": "https://www.ensembl.org/id/ENSGALT00010050900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030091.1", "url": "https://www.ensembl.org/id/ENSGALP00010030091.1" } ] } }, { "isoform_ac": "A0A8V0ZGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0ZGX4-1", "sequence": { "sequence": "MDLLEQVSSSKQAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGHPLHNTGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 170, "header": "tr|A0A8V0ZGX4-1|A0A8V0ZGX4_CHICK Computationally mapped isoform of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1420882, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050887.1", "url": "https://www.ensembl.org/id/ENSGALT00010050887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030078.1", "url": "https://www.ensembl.org/id/ENSGALP00010030078.1" } ] } }, { "isoform_ac": "A0A8V0ZGZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X6/entry#A0A8V0ZGZ2-1", "sequence": { "sequence": "MDLLEQVSSLLRTLQDKVPTFLQPQYWLRSWMWQVWMELIKAAQAVAGAASTAAFFLCEGLLGQHFDVVPNGVAEPQPGDLFLFPLASGGPGWWGAHAGVYCGDGEIIHLEGTSGTSPTGIVAKHGKSHLVRTRGPAKVLRMKGGLDAAALQWRIQAAMDMVLEYDAVTCNCIHFALALLGLGQLNGDMMFPALQ", "length": 195, "header": "tr|A0A8V0ZGZ2-1|A0A8V0ZGZ2_CHICK Computationally mapped isoform of LRAT domain-containing protein OS=Gallus gallus OX=9031 GN=LOC415324 PE=4 SV=1 CANONICAL=A0A8V0Z9X6-1" }, "locus": { "chromosome": "10", "start_pos": 1420882, "end_pos": 1419203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050902.1", "url": "https://www.ensembl.org/id/ENSGALT00010050902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030093.1", "url": "https://www.ensembl.org/id/ENSGALP00010030093.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9X4-1", "uniprot_ac": "A0A8V0Z9X4", "uniprot_id": "A0A8V0Z9X4_CHICK", "mass": { "chemical_mass": 39938.0, "monoisotopic_mass": 39938.0 }, "refseq": {}, "gene_names": [ { "name": "MXD1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4" } ] } ], "protein_names": [ { "name": "MAX dimerization protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MXD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4", "locus": { "chromosome": "22", "start_pos": 3407184, "end_pos": 3399491, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019577", "url": "https://www.ensembl.org/id/ENSGALG00010019577" } ] } } ], "crossref": [ { "id": "A0A8V0Z9X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9X4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPPPGPHRAARWPCTPRHPSPPQAVGGHTGDVPYWGLKVQSHDVAGKDDFGLRFGCSLVWCTALGFRLEAVEVVDEIQIQSLRWGGVLLPRSVTRGGSLLLLPAPSCCLLREEQLCHLTGTAPRPAPAHVAWGRVTFASCDSRTSPSRLRSEVPFWGDVELHSSLWHCSRGMGAAGRVLWSYSRTSETRWSCAPLGLGSTHNEMEKNRRAHLRLCLEKLKVLVPLGPESSKHTTLSLLMKAKLHIKKLEDYDRRALHQIEQLQREQRHLKRQLEKLGSERVRTDSVGSAVSSERSDSDREEIDVDVESTDSLPADLDWSSSSPSDSDERGSLQSVCSDEGYASSGVRRAKAQSAHKLCPAL", "length": 362, "header": "tr|A0A8V0Z9X4-1|A0A8V0Z9X4_CHICK Isoform 1 of MAX dimerization protein 1 OS=Gallus gallus OX=9031 GN=MXD1 PE=4 SV=1 CANONICAL=A0A8V0Z9X4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4/entry#A0A8V0Z9X4-1", "sequence": { "sequence": "MGPPPGPHRAARWPCTPRHPSPPQAVGGHTGDVPYWGLKVQSHDVAGKDDFGLRFGCSLVWCTALGFRLEAVEVVDEIQIQSLRWGGVLLPRSVTRGGSLLLLPAPSCCLLREEQLCHLTGTAPRPAPAHVAWGRVTFASCDSRTSPSRLRSEVPFWGDVELHSSLWHCSRGMGAAGRVLWSYSRTSETRWSCAPLGLGSTHNEMEKNRRAHLRLCLEKLKVLVPLGPESSKHTTLSLLMKAKLHIKKLEDYDRRALHQIEQLQREQRHLKRQLEKLGSERVRTDSVGSAVSSERSDSDREEIDVDVESTDSLPADLDWSSSSPSDSDERGSLQSVCSDEGYASSGVRRAKAQSAHKLCPAL", "length": 362, "header": "tr|A0A8V0Z9X4-1|A0A8V0Z9X4_CHICK Isoform 1 of MAX dimerization protein 1 OS=Gallus gallus OX=9031 GN=MXD1 PE=4 SV=1 CANONICAL=A0A8V0Z9X4-1" }, "locus": { "chromosome": "22", "start_pos": 3404096, "end_pos": 3400725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047213.1", "url": "https://www.ensembl.org/id/ENSGALT00010047213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027989.1", "url": "https://www.ensembl.org/id/ENSGALP00010027989.1" } ] } }, { "isoform_ac": "A0A8V0ZAP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4/entry#A0A8V0ZAP7-1", "sequence": { "sequence": "MGDSEGRDLPRGRANRGRACLPATQSRKATEERHPMSGGGGRGWRSGRARRSPRLGPSRPRSAAMAAVGDDGSGVGSSIGLLLEAAEYLERREREAEHGYASLLPGAGRARRESPRRRGKGRRSGGGGRSTHNEMEKNRRAHLRLCLEKLKVLVPLGPESSKHTTLSLLMKAKLHIKKLEDYDRRALHQIEQLQREQRHLKRQLEKLGSERVRTDSVGSAVSSERSDSDREEIDVDVESTDSLPADLDWSSSSPSDSDERGSLQSVCSDEGYASSGVRRAKAQSAHKLCPAL", "length": 292, "header": "tr|A0A8V0ZAP7-1|A0A8V0ZAP7_CHICK Computationally mapped isoform of MAX dimerization protein 1 OS=Gallus gallus OX=9031 GN=MXD1 PE=4 SV=1 CANONICAL=A0A8V0Z9X4-1" }, "locus": { "chromosome": "22", "start_pos": 3404096, "end_pos": 3399494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047217.1", "url": "https://www.ensembl.org/id/ENSGALT00010047217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027991.1", "url": "https://www.ensembl.org/id/ENSGALP00010027991.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", 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"reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9X4" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 249, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 95 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9Y5-1", "uniprot_ac": "A0A8V0Z9Y5", "uniprot_id": "A0A8V0Z9Y5_CHICK", "mass": { "chemical_mass": 24971.0, "monoisotopic_mass": 24971.0 }, "refseq": {}, "gene_names": [ { "name": "GLTP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5" } ] } ], "protein_names": [ { "name": "Glycolipid transfer protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5#function" }, { "database": "UniProtKB", "id": "ARBA00037246", "url": "https://www.uniprot.org/uniprotkb/ARBA00037246#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLTP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5", "locus": { "chromosome": "15", "start_pos": 6861603, "end_pos": 6863786, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021041", "url": "https://www.ensembl.org/id/ENSGALG00010021041" } ] } } ], "crossref": [ { "id": "A0A8V0Z9Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR014830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Y5", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10219:SF97", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10219:SF97", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RAAGSVPGRCGPGRAGHGAAAGARVPAAAGRQADRDAALPGGRGAPAALLRLPGDAHRILTRQSRPGREHQENPGRLRLQPQQVQNAAEHPGGGEGDARRCLAQDGRYAGADVAEEVTMGLKFMLVLLQSISDGERDEEHPNLIRVNAMKAYEIALKKYHGWMLQKLFMGSVYALPYKSDLLKALEKGREVKEEESIEKIHQFLARVTPILDAIYEMYTRMNAELSYKA", "length": 229, "header": "tr|A0A8V0Z9Y5-1|A0A8V0Z9Y5_CHICK Isoform 1 of Glycolipid transfer protein OS=Gallus gallus OX=9031 GN=GLTP PE=1 SV=1 CANONICAL=A0A8V0Z9Y5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y5/entry#A0A8V0Z9Y5-1", "sequence": { "sequence": "RAAGSVPGRCGPGRAGHGAAAGARVPAAAGRQADRDAALPGGRGAPAALLRLPGDAHRILTRQSRPGREHQENPGRLRLQPQQVQNAAEHPGGGEGDARRCLAQDGRYAGADVAEEVTMGLKFMLVLLQSISDGERDEEHPNLIRVNAMKAYEIALKKYHGWMLQKLFMGSVYALPYKSDLLKALEKGREVKEEESIEKIHQFLARVTPILDAIYEMYTRMNAELSYKA", "length": 229, "header": "tr|A0A8V0Z9Y5-1|A0A8V0Z9Y5_CHICK Isoform 1 of Glycolipid transfer protein OS=Gallus gallus OX=9031 GN=GLTP PE=1 SV=1 CANONICAL=A0A8V0Z9Y5-1" }, "locus": { "chromosome": "15", "start_pos": 6863762, "end_pos": 6862102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050908.1", "url": "https://www.ensembl.org/id/ENSGALT00010050908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030099.1", "url": "https://www.ensembl.org/id/ENSGALP00010030099.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z9Z5-1", "uniprot_ac": "A0A8V0Z9Z5", "uniprot_id": "A0A8V0Z9Z5_CHICK", "mass": { "chemical_mass": 60627.0, "monoisotopic_mass": 60627.0 }, "refseq": {}, "gene_names": [ { "name": "API5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ] } ], "protein_names": [ { "name": "Apoptosis inhibitor 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "API5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5", "locus": { "chromosome": "5", "start_pos": 20958277, "end_pos": 20942079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021048", "url": "https://www.ensembl.org/id/ENSGALG00010021048" } ] } } ], "crossref": [ { "id": "A0A8V0Z9Z5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z9Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Z5", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA09", "url": "https://www.orthodb.org/?gene=A0A8V0ZA09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH20", "url": "https://www.orthodb.org/?gene=A0A8V0ZH20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH25", "url": "https://www.orthodb.org/?gene=A0A8V0ZH25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH38", "url": "https://www.orthodb.org/?gene=A0A8V0ZH38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN55", "url": "https://www.orthodb.org/?gene=A0A8V0ZN55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEEVSVVEIDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYGKLGSLEKLCPITVVPLGVGGKCKLSTFSEGHIVLSPIFVCNDLFLTAHQLVFEYRQPI", "length": 543, "header": "tr|A0A8V0Z9Z5-1|A0A8V0Z9Z5_CHICK Isoform 1 of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0Z9Z5-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEEVSVVEIDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYGKLGSLEKLCPITVVPLGVGGKCKLSTFSEGHIVLSPIFVCNDLFLTAHQLVFEYRQPI", "length": 543, "header": "tr|A0A8V0Z9Z5-1|A0A8V0Z9Z5_CHICK Isoform 1 of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20954846, "end_pos": 20943431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050918.1", "url": "https://www.ensembl.org/id/ENSGALT00010050918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030109.1", "url": "https://www.ensembl.org/id/ENSGALP00010030109.1" } ] } }, { "isoform_ac": "A0A8V0ZA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0ZA09-1", "sequence": { "sequence": "MHCTAYAGGGRQKNKPRGKCSSNVALRSVGAALAPLLESHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 539, "header": "tr|A0A8V0ZA09-1|A0A8V0ZA09_CHICK Computationally mapped isoform of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20956221, "end_pos": 20942828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050934.1", "url": "https://www.ensembl.org/id/ENSGALT00010050934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030125.1", "url": "https://www.ensembl.org/id/ENSGALP00010030125.1" } ] } }, { "isoform_ac": "A0A8V0ZH20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0ZH20-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 484, "header": "tr|A0A8V0ZH20-1|A0A8V0ZH20_CHICK Computationally mapped isoform of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20956221, "end_pos": 20943431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050927.1", "url": "https://www.ensembl.org/id/ENSGALT00010050927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030118.1", "url": "https://www.ensembl.org/id/ENSGALP00010030118.1" } ] } }, { "isoform_ac": "A0A8V0ZH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0ZH25-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKAVKKEQVKIQPQVHLQRKLRQDQKGMPGRYIILPVENTVVTWAVFLTSKEVVSGVDEEEAGEDVAIVVEEESTE", "length": 522, "header": "tr|A0A8V0ZH25-1|A0A8V0ZH25_CHICK Computationally mapped isoform of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20956225, "end_pos": 20943431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050933.1", "url": "https://www.ensembl.org/id/ENSGALT00010050933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030124.1", "url": "https://www.ensembl.org/id/ENSGALP00010030124.1" } ] } }, { "isoform_ac": "A0A8V0ZH38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0ZH38-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 493, "header": "tr|A0A8V0ZH38-1|A0A8V0ZH38_CHICK Computationally mapped isoform of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20956221, "end_pos": 20943431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050921.1", "url": "https://www.ensembl.org/id/ENSGALT00010050921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030112.1", "url": "https://www.ensembl.org/id/ENSGALP00010030112.1" } ] } }, { "isoform_ac": "A0A8V0ZN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5/entry#A0A8V0ZN55-1", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDFKGLGFKTLQRISSTFPLLIKVQSRCPGNRYRRQMQIKKEQVKIQPQVHLQRKLRQDQKGMPGRYIILPVENTVVTWAVFLTSKEVVSGVDEEEAGEDVAIVVEEESTE", "length": 536, "header": "tr|A0A8V0ZN55-1|A0A8V0ZN55_CHICK Computationally mapped isoform of Apoptosis inhibitor 5 OS=Gallus gallus OX=9031 GN=API5 PE=3 SV=1 CANONICAL=A0A8V0Z9Z5-1" }, "locus": { "chromosome": "5", "start_pos": 20956225, "end_pos": 20943431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050924.1", "url": "https://www.ensembl.org/id/ENSGALT00010050924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030115.1", "url": "https://www.ensembl.org/id/ENSGALP00010030115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z9Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"url": "https://www.ensembl.org/id/ENSGALP00010027470.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 383, "end_pos": 385 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA06-1", "uniprot_ac": "A0A8V0ZA06", "uniprot_id": "A0A8V0ZA06_CHICK", "mass": { "chemical_mass": 40677.0, "monoisotopic_mass": 40677.0 }, "refseq": { "ac": "XP_421464", "name": "cyclin-dependent kinase-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421464" }, "gene_names": [ { "name": "CDKL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "name": "CDKL1", "type": "synonym", "evidence": [ { "id": "XP_421464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421464" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase-like 1", "type": "synonym", "evidence": [ { "id": "XP_421464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421464" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421464.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421464" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDKL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06", "locus": { "chromosome": "5", "start_pos": 57551540, "end_pos": 57560511, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019271", "url": "https://www.ensembl.org/id/ENSGALG00010019271" } ] } } ], "crossref": [ { "id": "A0A8V0ZA06", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA06", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07847", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07847", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423575", "url": "https://www.ncbi.nlm.nih.gov/gene/423575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423575", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHSTHYN", "url": "https://omabrowser.org/oma/group/LHSTHYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA06", "url": "https://www.orthodb.org/?gene=A0A8V0ZA06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERYEKLGKVGEGSYGVVFKCRNRETGQIVAIKKFLESEEDPVIRKIALREVRMLKQLKHPNLVNLLEVFRRKRKLHLVFEYCDHTVLHELDKHPRGVPEQLVRSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARMLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRRTLGDLIPRHQQVFSTNQFFSGVTIPDPESMEPLEMKFPSISYPALALMKGCLRMDPAERQTCEQLLQHPYFDSVREAGDVGKEHEKAARRPAKLTRKHVPGFQYLPQLSSSNVLPALDSKKYFCKTRKSNYHFPNI", "length": 352, "header": "tr|A0A8V0ZA06-1|A0A8V0ZA06_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDKL1 PE=3 SV=1 CANONICAL=A0A8V0ZA06-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06/entry#A0A8V0ZA06-1", "sequence": { "sequence": "MERYEKLGKVGEGSYGVVFKCRNRETGQIVAIKKFLESEEDPVIRKIALREVRMLKQLKHPNLVNLLEVFRRKRKLHLVFEYCDHTVLHELDKHPRGVPEQLVRSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARMLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRRTLGDLIPRHQQVFSTNQFFSGVTIPDPESMEPLEMKFPSISYPALALMKGCLRMDPAERQTCEQLLQHPYFDSVREAGDVGKEHEKAARRPAKLTRKHVPGFQYLPQLSSSNVLPALDSKKYFCKTRKSNYHFPNI", "length": 352, "header": "tr|A0A8V0ZA06-1|A0A8V0ZA06_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDKL1 PE=3 SV=1 CANONICAL=A0A8V0ZA06-1" }, "locus": { "chromosome": "5", "start_pos": 57560460, "end_pos": 57552936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046594.1", "url": "https://www.ensembl.org/id/ENSGALT00010046594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027752.1", "url": "https://www.ensembl.org/id/ENSGALP00010027752.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423575", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZXQ3-1", "protein_name": "cyclin-dependent kinase", "gene_name": "CDKL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKRLKHPNLVNLIEVFRRKKKLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAINFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGMPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVEIPDPEDMEPLELKFPNISYPALGLLKGCLHMNPVERLTCEQLLQHPYFDSIRESGDLAKEHEKPTRKTLRQSRKHLPGLQYLPQLTSSSILPALDNKKYYCNTKKLNYRFPNI", "length": 352 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7K953-1", "protein_name": "Cyclin-dependent kinase-like 1 isoform X1", "gene_name": "Cdkl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIEEGGGLRCQIHRLVHHPFQGYHSGPQNSPNEKSSGCPSVHCLLGLPAAPSLTITSLSMQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLMKSIIWQTLQAVNFCHKHNKLSLNKKALGSFSRVPLGSFALLKNAARSQAMRHTQGGQEPPAAEHWPRCGTELTSSDSPQRCIHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLESKFPNISYPALGFLKGCLHMDPAERLTCEQLLQHPYFDSIREVGDLTRQHDKSVRKTLRQSRKHLTGLQYLPQLTSSSILPALDNKKYHCSTKKLNYHFPNI", "length": 419 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P43294-1", "protein_name": "Serine/threonine-protein kinase MHK", "gene_name": "MHK", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMVFVVFVMCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHIIKLKEIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPENLLVTNNILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSISHTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFSMATQASYPIHDLELRLDNMAALPNLELNLWDFNREPEECFLGLTLAVKPSAPKLEMLRNVSQDMSENFLFCPGVNNDREPSVFWSLLSPDENGLHAPVESSPLSLSFSPMQQHTVGPPQSSGFTMTSSMQPNMLDRPWMAVSAPFQQSHYL", "length": 443 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q00532-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "CDKL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEHNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI", "length": 357 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66HE7-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "Cdkl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRDVGELARPHDKPTRKTLRQSRKHLTGLQHLPQLTSSSVLPALDRKKYHCGTRNFNYHFPNI", "length": 352 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CEQ0-1", "protein_name": "Cyclin-dependent kinase-like 1", "gene_name": "Cdkl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKQSAIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIREVGELTRQHDKPARKTLRQSRKHLTGLQYLPQLTSSRILPALDNKKYHCSTKRFNYHFPNI", "length": 352 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMN3-1", "protein_name": "Cyclin-dependent kinase-like 2", "gene_name": "Cdkl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFHSSSFYLPQSLQNSFLYRLIQKIQVCNEPDLVETRQYRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNSLEAANLRQQQLASQQFMLATAAQQLQTGPAQAAAIAAARDKSKTSNTSLPLLPSTQHHHHPHQDYVKLQPLNKNANLLHRTEHHLPTI", "length": 438 }, "evidence": [ { "id": "A0A8V0ZA06", "url": "https://omabrowser.org/oma/group/A0A8V0ZA06/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA21-1", "uniprot_ac": "A0A8V0ZA21", "uniprot_id": "A0A8V0ZA21_CHICK", "mass": { "chemical_mass": 46807.0, "monoisotopic_mass": 46807.0 }, "refseq": { "ac": "XP_046759246", "name": "arylacetamide deacetylase-like 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759246" }, "gene_names": [ { "name": "LOC121106479", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21" } ] }, { "name": "LOC121106479", "type": "synonym", "evidence": [ { "id": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759246" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106479", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZA21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA21", "database": "AlphaFoldDB", "categories": [] }, { "id": "121106479", "url": "https://www.ncbi.nlm.nih.gov/gene/121106479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FCCRYLN", "url": "https://omabrowser.org/oma/group/FCCRYLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA21", "url": "https://www.orthodb.org/?gene=A0A8V0ZA21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759246", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASIYKCLAGLGVILISPVVVPALFWGRFLCDLLHLELPPGIDQPLKLLFYHLLLITTMVLGKILETLGICSDLSLLRLVVDGIPPWRDSNLLIKDLVVDEVPLRIYQPKWPPAGKRRGILYFHGGAGTFGSIRAFERVCRYIAKKCDSVVVSVGYRLAPEHPYPGQYSDCLNATLYFMRNLDEYHVDPALIILGGDSCGANFATVICQILVNKRDLPKVRAQILLYPGLQGLDFQLPSYQQNALIPILSRKLVIYFCFRYLNRKPSYLEDIIQNCHVPESTKWKYKKWISADNIPDEFKIRGYKPQKLTSYKPEVHEAVKEVLAMTFSPLLAEDAIICQLPESYIVTCEFDVLRDDGLLYKKRLEDNGIRVTWYHSEGGFHGILAFFGYGIFSFLSGKKIMDNTVNYINSL", "length": 412, "header": "tr|A0A8V0ZA21-1|A0A8V0ZA21_CHICK Isoform 1 of Alpha/beta hydrolase fold-3 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106479 PE=3 SV=1 CANONICAL=A0A8V0ZA21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21/entry#A0A8V0ZA21-1", "sequence": { "sequence": "MASIYKCLAGLGVILISPVVVPALFWGRFLCDLLHLELPPGIDQPLKLLFYHLLLITTMVLGKILETLGICSDLSLLRLVVDGIPPWRDSNLLIKDLVVDEVPLRIYQPKWPPAGKRRGILYFHGGAGTFGSIRAFERVCRYIAKKCDSVVVSVGYRLAPEHPYPGQYSDCLNATLYFMRNLDEYHVDPALIILGGDSCGANFATVICQILVNKRDLPKVRAQILLYPGLQGLDFQLPSYQQNALIPILSRKLVIYFCFRYLNRKPSYLEDIIQNCHVPESTKWKYKKWISADNIPDEFKIRGYKPQKLTSYKPEVHEAVKEVLAMTFSPLLAEDAIICQLPESYIVTCEFDVLRDDGLLYKKRLEDNGIRVTWYHSEGGFHGILAFFGYGIFSFLSGKKIMDNTVNYINSL", "length": 412, "header": "tr|A0A8V0ZA21-1|A0A8V0ZA21_CHICK Isoform 1 of Alpha/beta hydrolase fold-3 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106479 PE=3 SV=1 CANONICAL=A0A8V0ZA21-1" }, "locus": { "chromosome": "21", "start_pos": 5273834, "end_pos": 5268675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050944.1", "url": "https://www.ensembl.org/id/ENSGALT00010050944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030135.1", "url": "https://www.ensembl.org/id/ENSGALP00010030135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZA21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA21" }, { "id": "PF07859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha/beta hydrolase fold-3", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 263, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAV0-1", "uniprot_ac": "A0A8V0ZAV0", "uniprot_id": "A0A8V0ZAV0_CHICK", "mass": { "chemical_mass": 88318.0, "monoisotopic_mass": 88318.0 }, "refseq": { "ac": "XP_004945190", "name": "MICAL-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945190" }, "gene_names": [ { "name": "MICALL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ] }, { "name": "MICALL2", "type": "synonym", "evidence": [ { "id": "XP_004945190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945190" } ] } ], "protein_names": [ { "name": "MICAL like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0/entry#names_and_taxonomy" } ] }, { "name": "MICAL-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945190" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MICALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0", "locus": { "chromosome": "14", "start_pos": 2531144, "end_pos": 2554643, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019614", "url": "https://www.ensembl.org/id/ENSGALG00010019614" } ] } } ], "crossref": [ { "id": "A0A8V0ZAV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416460", "url": "https://www.ncbi.nlm.nih.gov/gene/416460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416460", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416460", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWFQLIH", "url": "https://omabrowser.org/oma/group/DWFQLIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA24", "url": "https://www.orthodb.org/?gene=A0A8V0ZA24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZAV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIQNLQLWCKQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNSLSKENVYENNKLAFQVASEQLGIPALLDAEDMVALRVPDRLSIITYVSQYYNYFHGRSPIGGMAGIKRSSSELQEQPAGKKAVPEPPKPVSPKLPSAHPPAKAKPKEASPVPTKGVLTESGNIRSSCCGICGNHVHLVQRHLVDGKLYHRNCFRCRECWNVLLPGSYKAGPEPGTFICTSHQQPDSVQISGLSSTQNKPESTPTPTSARAFQKAAEPKKQEQVLKKPSQEGLANSTKPSVSSSGSSGFRSLNTPWSSSAVNKSDDCKGIPLGNKTDHHEGTTSGPLWTTSKTKTQQARENFFQSLESSSNKTSDAKNHDPSHSSGKKSSGRTATEVTLVKTEKAQARNNIIQALAGSNTSPSRPGGLSSTGSSASSSSNFSPSSSQSQSPALKAQTSKTGYTAPKQEKITEPLPKSQTTSKPVESVHKPESKGLKGTANAGEDKSESPADWRSRLKPVAHKDQAGSKKPTDHSQVGTGSPTQKEKKPTPLVVPSAKQESASSGGILKKKLIPSPDLGNFQNSKQRWKDHGVSAKKEEESSHQLNQNTVTFQSSIPKSIQSSEAVSPTKLHPDYLPEEEIQKKVRDIEKQLDILELKGVDLEKQLRGCEGDESEDALMVDWFKLIHEKQLLLRQESELMYKMKQQNLEEQQWNIELELRRLVDKPEYLKTRREKEREKELLDSYLNTVNDRNNIVECLDEDRIREKEEDQMLADMIRKLDGSLEGQETEKKKNKFRLSKIWKQKNKS", "length": 798, "header": "tr|A0A8V0ZAV0-1|A0A8V0ZAV0_CHICK Isoform 1 of MICAL like 2 OS=Gallus gallus OX=9031 GN=MICALL2 PE=1 SV=1 CANONICAL=A0A8V0ZAV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0/entry#A0A8V0ZA24-1", "sequence": { "sequence": "MAAIQNLQLWCKQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNSLSKENVYENNKLAFQVASEQLGIPALLDAEDMVALRVPDRLSIITYVSQYYNYFHGRSPIGGMAGIKRSSSELQEQPAGKKAVPEPPKPVSPKLPSAHPPAKAKPKEASPVPTKGVLTESGNIRSSCCGICGNHVHLVQRHLVDGKLYHRNCFRCRECWNVLLPGSYKAGPEPGTFICTSHQQPDSVQISGLSSTQNKPESTPTPTSARAFQKAAEPKKQEQVLKKPSQEGLANSTKPSVSSSGSSGFRSLNTPWSSSAVNKSDDCKGIPLGNKTDHHEGTTSGPLWTTSKTKTQQARENFFQSLESSSNKTSDAKNHDPSHSSGKKSSGRTATEVTLVKTEKAQARNNIIQALAGSNTSPSRPGGLSSTGSSASSSSQSQSPALKAQTSKTGYTAPKQEKITEPLPKSQTTSKPVESVHKPESKGLKGTANAGEDKSESPADWRSRLKPVAHKDQAGSKKPTDHSQVGTGSPTQKEKKPTPLVVPSAKQESASSGGILKKKLIPSPDLGNFQNSKQRWKDHGVSAKKEEESSHQLNQNTVTCKISSTYLKPFSALPGDNFSGASQAKEFSGKGRN", "length": 628, "header": "tr|A0A8V0ZA24-1|A0A8V0ZAV0_CHICK Computationally mapped isoform of MICAL like 2 OS=Gallus gallus OX=9031 GN=MICALL2 PE=1 SV=1 CANONICAL=A0A8V0ZAV0-1" }, "locus": { "chromosome": "14", "start_pos": 2554578, "end_pos": 2538391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047314.1", "url": "https://www.ensembl.org/id/ENSGALT00010047314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028039.1", "url": "https://www.ensembl.org/id/ENSGALP00010028039.1" } ] } }, { "isoform_ac": "A0A8V0ZAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0/entry#A0A8V0ZAV0-1", "sequence": { "sequence": "MAAIQNLQLWCKQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNSLSKENVYENNKLAFQVASEQLGIPALLDAEDMVALRVPDRLSIITYVSQYYNYFHGRSPIGGMAGIKRSSSELQEQPAGKKAVPEPPKPVSPKLPSAHPPAKAKPKEASPVPTKGVLTESGNIRSSCCGICGNHVHLVQRHLVDGKLYHRNCFRCRECWNVLLPGSYKAGPEPGTFICTSHQQPDSVQISGLSSTQNKPESTPTPTSARAFQKAAEPKKQEQVLKKPSQEGLANSTKPSVSSSGSSGFRSLNTPWSSSAVNKSDDCKGIPLGNKTDHHEGTTSGPLWTTSKTKTQQARENFFQSLESSSNKTSDAKNHDPSHSSGKKSSGRTATEVTLVKTEKAQARNNIIQALAGSNTSPSRPGGLSSTGSSASSSSNFSPSSSQSQSPALKAQTSKTGYTAPKQEKITEPLPKSQTTSKPVESVHKPESKGLKGTANAGEDKSESPADWRSRLKPVAHKDQAGSKKPTDHSQVGTGSPTQKEKKPTPLVVPSAKQESASSGGILKKKLIPSPDLGNFQNSKQRWKDHGVSAKKEEESSHQLNQNTVTFQSSIPKSIQSSEAVSPTKLHPDYLPEEEIQKKVRDIEKQLDILELKGVDLEKQLRGCEGDESEDALMVDWFKLIHEKQLLLRQESELMYKMKQQNLEEQQWNIELELRRLVDKPEYLKTRREKEREKELLDSYLNTVNDRNNIVECLDEDRIREKEEDQMLADMIRKLDGSLEGQETEKKKNKFRLSKIWKQKNKS", "length": 798, "header": "tr|A0A8V0ZAV0-1|A0A8V0ZAV0_CHICK Isoform 1 of MICAL like 2 OS=Gallus gallus OX=9031 GN=MICALL2 PE=1 SV=1 CANONICAL=A0A8V0ZAV0-1" }, "locus": { "chromosome": "14", "start_pos": 2554578, "end_pos": 2532587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047321.1", "url": "https://www.ensembl.org/id/ENSGALT00010047321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028041.1", "url": "https://www.ensembl.org/id/ENSGALP00010028041.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416460", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416460", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEN0-1", "protein_name": "MICAL-like protein 2", "gene_name": "Micall2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKIPDRLSILTYVSQYYNYFHGRSPIGGMAGMKRPSSDSTEELSGKKKVPSQPAKLSSPVPTQRLPLSPARTNPVVQRNEGVSERPSPKAAPGTVGSSVSSICGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCTHHSSEAVSVSPKLSNLASRQPGGGIADTRPIGVSQKVLETNGEATPLRARTAAWEHAGGNRAAKGFVQTELTPPATSRVHVGSPAGPRLPMSTVTTTSANSKATTHVTNSSPVGWSSSAQSSTGTSGSRPVVSPSALGAHLSVPQGQAASKGVKTQLNSSTDSSSTAPTPAWTSSSSRTQQAREKFFHNLSPAPAPAPASSSSSHASRVPTVVTAPSGKVSPLVNTSTSKVPSATVVTVPTSKASTVVTAPTSKAPTVVTVPISKAPTVVTAPTSKVSTVVTVPTSKASTVVTAPTSKASTVVTVPTGRGHVVVNTSASKVSGVVDNPAQESSREQALSVLRKALPGLTRAGSQAPSRSSPATSSVLITLPKNEVPPKVPSAKLSHSTTQAFSPTPKMEPTAPLSVGSTSWTSVSLQAGKKSPGISPGIGKTSAVSRPQAEVKGTSGPGPTSQEGQEEGPEGWRARLKPVDKSIPSARALEQKEPVLAEPRAGDTPRKASSSSDSSIHITLTPIQQKRTPCLADSGSSLAAPSPPSRRKKLVVPPTLDVSADWLQPELKKQDDQTRSCKEKTATWGTRESSAILDNDLVSPDEAVTSPVRLHPNYISQEELQRQLQDIERQLDALELRGVELEKRLRAAEGDASEDGLMVDWFRLIHEKQLLLRRESELMYKSKDQCLEERQLDLQGELRRLMEKPEGLKSPQDRKREQELLNQYVNTVNDRSDIVDNLDEDRLREQEEDQMLESMIQNLGLQRKKSKSFLSKIWSSKSKSGQT", "length": 1014 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QAZ3-1", "protein_name": "MICAL-like protein 1", "gene_name": "micall2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVKALQQWCKIQCEGYRDVSITNMTTSFRDGLAFCALIHKHRPDLIDFDSLSKENIYENNQRAFEVAEKELGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMGGIKRPAEESNEAPSGKKNPPVIAKVLPSPKPATENKTPKPANENKREVLTERANKSSTPSSNCSVCNQHVHLVQRHLVDGKLYHRNCFKCKECSTILLSGTYKAGKEPGTFICKTHTSIEKPLTTRFTAPSKTQSTFINKPDQSALGGSTGKASLNTNTSKLGWLANKSDRIPMRGFTDTPTPAVQLTPTAKATPTPDTTTAKSPSGPRSATESLKPVSNTVQKNQEARMRFFESSSSSPSSVVPASKSTSSYTSTTSVSTAGVKTTAPETTTPRVPAGAGKGRVLLRVGDWAKSQDTEKEKENEKEKEKAKAVIGKMVKVDKDSNSSSASPAGLKANSSNVPPLESNAKAPFGRVRLKALEASGETTAPATTVPSWMKEKSLSRNVNTPSSNSKENDTVPSDWRSMLKPVSKPVSNLESKGLPARRTEAVSSPKTSVPASSTTTISISISSSKTPLTTPLKNGSKPNDSSSVFPVSPSGTETHKSHKPGYIPKEDIQKELKEIEMNMNELEKKGVELEKQLRQCDEDGEEDALMNDLMVDWFTLIRNKQVYMRRESELVYIARTQDLEEEQPSVDAELRRLMEKPDHLKTLWDRKREEELMAKLVEIVNDRNAIVEGLDEDRLREEEEDEQLNKMMQSFDMKKEKVKKMSPVTRWFSMRKRRSSED", "length": 783 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RIV6-1", "protein_name": "MICAL like 2", "gene_name": "MICALL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAITALQQWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNALRKENIYENNQLAFRVAEEQLGIPALLDAEDMVALRVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPPSDSSEEPSGKKAPSQPARPLPTPARGQPLSPVSTNPTVPRKEGGTEGPPRKAGPASAPSSVSGTCGICGQHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCSSHHPETASASPHGPTDSKLPGAPRKAQEAQEAHGQRDAGPKARPPAWEPRVGNVTARGFAPATADPPATTASSHAPMGSPAGPRFSAGLAPGKASTHVTNSSPTGWSLPPGSSRPATTPSALDPRPATPQGQVTPKVAAPQTKLSSRPASPAPAKAPASTSSTSRMQQARERFFQTPGAALDQRPAGKVPAATEDAASRDSSKAQARSFLQKALPELREAGSQAPGRPSLAPAPALNSHPRTEGSGANPSAKLSRLASPQAPNPAARTEPPAPLSVGSTMRASPQAGKKVSPAPSGAVKAGAGSRPKPEAPLAKGPAAGPQEGQEDGPAGWRARLKPVEKKSPPERALELKEPQVRGEPRVGSTPGKASGSSEGGIRVTLTPVPADRTPGPAGPGASLSAASPSPSPARRRKLAVPASLDVSGNWLQPEPSGREAPAWSWKQEDKPGRPLGPAGVPAPPGKSVTSPGRLHPDYVPQEEIQRQVRDIERQLDVLELRGVELEKRLRAAEGDVAEDALMVDWFRLIHEKQLLLRLESELMYKARDQRLEEQQQDLEGELRRLMAKPEGLKSPQDRQREQDLLNQYVTTVNDRSDIVDFLDEDRLREQEEDQMLQSMIQKLDLQRSGGDQRKKPKFRLSNIWSPKSRSRTPE", "length": 887 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6REL8-1", "protein_name": "MICAL like 2", "gene_name": "MICALL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAIKALQQWCRQQCEGYRDVSITDMTTSFRDGLAFCAILHRHRPDLINFDALRKENVYENNKLAFSVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFQRGASAERTAGVKRPSSNASEEPSGKKAPTQPIQPAPGPARGQPLSPVSTNRTVQRKDGGTEGPPQKAGQAAGGSLNSSCGVCGQHVHLMQRHLADGRLYHRGCFRCKQCSSTLHSGAYRATGEPGVFICSSHHPETTSASPTLPSLASRRHGAMSMDSETPGGLRKTREASGQRDVGPKARLPGWDAVAGSTSARGSAPAATDPPAPASSRVPTGSPAAPRLMVGPAGGEAGTHVTSSSLTVWPSPAGRPRPTGTPSAPDPCPATPQGWATPRVSAPQTKLSSRPASPVPASTPAWTPSSSKTQQARERFFQTPGAAPGPGPAAADMPSRDGRKEQALSFLRKTLPELGAPGRAGGRGSERQRAPTTATPAPSSHPRSEGPGASPPARASLPTSPQTLSSPARMGPPATPGVGSTSWASQEAKKGSAASSGAVGAGAGSRLKLEAPLAKGPGASPQGSPEDQPAGWRARLKPVDKSPVDRAPEAKEPQVLREPRAGDAAGKASGSSKAGIRITLTSVRVDRMPGAAGPGASLPAASASASPLRKLAVPASLDVSGDWLQLEPSRKESPARSQKEEEKGPPQGKPGRPPGPAGVAAPPAKSAASPVRLHPDDMPPEIQRQVQDIERQLDALELQGVGLEKRLRAAEGDDSEDALMVDWFRLVHEKQLLLRLESELMYKARDQRLEEQQLDLEGELRRLMAKPEGLKSPQDRRREQDLLDQYVHTVNSRSDIIDFLDEDRLREQEEDEVLQSMIQKLDLQRSSEEQRKKPRFRLSSIWSPKSRSRTPE", "length": 893 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TN34-1", "protein_name": "MICAL-like protein 2", "gene_name": "Micall2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGIKRPSSDSTEELSGKKGLSQPAKLPSPAQTQRSPLSPARTNPVVQRNEGGSQRPSPKAAPGTAGSSVSSICGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCTHHSSEVTSVSPKSSNLASRKPGGVTADTRPFGVSWTVQEANGEGTPLRVRTAAWEHAGGNTTAKGFVQTELKPPSTSQVHVGSSAGPKLPTITVTTTSVTSKALTHVTNSSPIGWSSPAQSSPANFNSRPVVSPSARNTHLPGSQGQTASKGVKTQLNLNSESSNTAVTPAWTSSASKTQQAREKFFQTPPSAPAPASAPAPAPTSKVPTVVTVPTSKVPNVVTAPTSKVPTVVTVPTSKVPTVVSAPTSKVPTVVSAPTSKVPTVVNSTNSRVTTVVNAPTSKVPTVVSATNGRVPTVVTAHTGRVPAVMNTSASKVSPVVDAPAQESSREQALSVLRKALPALTGSGTQAPNRSFPATSSVLVTLPKNEVPQKVPSDKLSALTTQTPNFTIKLEPSAPVNVGNTAVFLQAGKKSPSISPRVGKTSVGSRPQAEVAGVKGPGPISQEGQEEGPEGWRARLKPVDKKTPAGRSLEQKEPVLAEPRIGDTSRKASSSSDSSVHITLTSIQHKRKPCPAGSGPSPAALSPSPSHRKKLAVPPSLDVSADWLQPEPKKQEDGTRSCKEEKSPTRWSRERSAVLDSGLAPPGEAVTSPVRLHPDYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDASEDSLMVDWFRLIHEKQLLLRLESELMYKSKDQRLEEQQLDLQGELRRLMDKPEGLKSPQDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQRKKSKSFLSKIWSSKSKSGQA", "length": 1009 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY33-1", "protein_name": "MICAL-like protein 2", "gene_name": "MICALL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQRKKSKFRLSKIWSPKSKSSPSQ", "length": 904 }, "evidence": [ { "id": "A0A8V0ZAV0", "url": "https://omabrowser.org/oma/group/A0A8V0ZAV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "filamin binding", "id": "GO:0031005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "actinin binding", "id": "GO:0042805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" }, { "name": "endosome membrane tubulation", "id": "GO:0097750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" }, { "id": "PS51848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BMERB", "eco_id": "ECO_0000259", "start_pos": 614, "end_pos": 765, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 107, "start_aa": "Met", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZAV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV0" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 240, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 258 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 796, "end_pos": 798 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZA25/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL37A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25", "locus": { "chromosome": "7", "start_pos": 22954381, "end_pos": 22957455, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019288", "url": "https://www.ensembl.org/id/ENSGALG00010019288" } ] } } ], "crossref": [ { "id": "A0A8V0ZA25", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA25", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA25", "url": "https://www.orthodb.org/?gene=A0A8V0ZA25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48188:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48188:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IVVVKKFHLTCCRLCIIPLPRDSLTRVAASQQLSHRGRGGESAADHRAPHPHGQTSPLCVTSGPRSPASGATAHTAPAHSNFLSLSLAAPGRKMAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRKAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 185, "header": "tr|A0A8V0ZA25-1|A0A8V0ZA25_CHICK Isoform 1 of Ribosomal protein L37a OS=Gallus gallus OX=9031 GN=RPL37A PE=3 SV=1 CANONICAL=A0A8V0ZA25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25/entry#A0A8V0ZA25-1", "sequence": { "sequence": "IVVVKKFHLTCCRLCIIPLPRDSLTRVAASQQLSHRGRGGESAADHRAPHPHGQTSPLCVTSGPRSPASGATAHTAPAHSNFLSLSLAAPGRKMAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRKAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ", "length": 185, "header": "tr|A0A8V0ZA25-1|A0A8V0ZA25_CHICK Isoform 1 of Ribosomal protein L37a OS=Gallus gallus OX=9031 GN=RPL37A PE=3 SV=1 CANONICAL=A0A8V0ZA25-1" }, "locus": { "chromosome": "7", "start_pos": 22957256, "end_pos": 22954479, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046637.1", "url": "https://www.ensembl.org/id/ENSGALT00010046637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027775.1", "url": "https://www.ensembl.org/id/ENSGALP00010027775.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" } ], 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA30-1", "uniprot_ac": "A0A8V0ZA30", "uniprot_id": "A0A8V0ZA30_CHICK", "mass": { "chemical_mass": 78218.0, "monoisotopic_mass": 78218.0 }, "refseq": {}, "gene_names": [ { "name": "ADD2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ] } ], "protein_names": [ { "name": "Adducin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30", "locus": { "chromosome": "22", "start_pos": 3395757, "end_pos": 3375674, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019291", "url": "https://www.ensembl.org/id/ENSGALG00010019291" } ] } } ], "crossref": [ { "id": "A0A8V0ZA30", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA30", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA30", "url": "https://www.orthodb.org/?gene=A0A8V0ZA30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAU6", "url": "https://www.orthodb.org/?gene=A0A8V0ZAU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGR6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10672", "database": "PANTHER", "categories": [ "Protein 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAASPEPPPSPPAPGPRYFERFPEDDPEYLRERNMAADLRQDFNMMEQKKRVTMILQSPSFREELESLIQEQMKKGNNSSHVWALRQIADFVATTSPAALPTSPMGLTAVTPINDLHGPDAPALAKGERLMRCKVGSVHRLLDLYGWAQLGHAAVTLRVSKEQEHFLVAPQGLACSEVTAASLIKVNVLGDVVEQGSTDFAPDARAFSLHAAIYAARPDARCIVRLHTPATAAVSAMRCGVLPISRAALLLGDIAYFDFRGEVEDEADRVELQKCLGPTCKILVLRNHGVLALGDTAEEAFYSIFHLQAACEVQVSALASAGGAENLIVLERAKHRPHEVGSVRWAGSTFGPMQKSRLGEHEFEALMRMLDNLVSGYRTGYTYRYPFVQEKSKPKSDVLIPATVTAFVFEEEAMPTPALRQHAQKQQKEKTRWLNTPNTYLRVSVAEEQQGGQKTKTTWLKADEVEKGSSGTAIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAETSRSPSTESHLGDAETKNPSQEEAPAEPEPPNPFSQLTDQELEEYKREVERKKLGLHGDKEAEETQASPPKSPPGSPKSPDKSAAPEGPEGDKKAEDGQAPADSSAEKEPPAVVNGKEEEQSTEESKGGDQTSAPANPEQDAPKEKSETVTSTPVSPEGSPSKSPSKKKKKFRTPSFLKKGKKKEKIES", "length": 714, "header": "tr|A0A8V0ZA30-1|A0A8V0ZA30_CHICK Isoform 1 of Adducin 2 OS=Gallus gallus OX=9031 GN=ADD2 PE=1 SV=1 CANONICAL=A0A8V0ZA30-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30/entry#A0A8V0ZA30-1", 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Transcript", "id": "ENSGALT00010046652.1", "url": "https://www.ensembl.org/id/ENSGALT00010046652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027782.1", "url": "https://www.ensembl.org/id/ENSGALP00010027782.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 418, "start_aa": "Thr", "end_pos": 418, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr418", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5223345", "name": "", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA53-1", "uniprot_ac": "A0A8V0ZA53", "uniprot_id": "A0A8V0ZA53_CHICK", "mass": { "chemical_mass": 52087.0, "monoisotopic_mass": 52087.0 }, "refseq": { "ac": "XP_004947632", "name": "TELO2-interacting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947632" }, "gene_names": [ { "name": "TTI2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53" } ] }, { "name": "TTI2", "type": "synonym", "evidence": [ { "id": "XP_004947632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947632" } ] } ], "protein_names": [ { "name": "TELO2 interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53/entry#names_and_taxonomy" } ] }, { "name": "TELO2-interacting protein 2", "type": "synonym", "evidence": [ { "id": "XP_004947632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947632" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947632.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947632" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53", "locus": { "chromosome": "22", "start_pos": 1774058, "end_pos": 1777575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017726", "url": "https://www.ensembl.org/id/ENSGALG00010017726" } ] } } ], "crossref": [ { "id": "A0A8V0ZA53", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA53", "database": "AlphaFoldDB", "categories": [] }, { "id": "426923", "url": "https://www.ncbi.nlm.nih.gov/gene/426923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426923", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426923", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHCSQGQ", "url": "https://omabrowser.org/oma/group/NHCSQGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA53", "url": "https://www.orthodb.org/?gene=A0A8V0ZA53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32226:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32226:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947632", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPQPPAEQVLRQLGQLLSQRPGVVTELGALLEAAEPRWLLGAGSPAALGELAAALSAFAALPEREQDAAELRDGDGAYAAAAERAADVGRVFLRLLAKLEAAKAEESLGPAVEPVLRRVMGHIYVLAVTHLAEGAWSSAGSRAVAAELLAALVRAAGCGTVAELLRGRKEEEEGGFAAIMGLLRPRLGKDTWKCNPATKHVFSWTLLHITRPWLSQHLERVLPASLLISDDYREENKVLGVHCLHHIVLNVPGADLCQFNRAQVVYHALYNHLYSREAPLIQAVLLCLLDLLPVLERAQRQQPRPTSPCDEVLQLVLTHMEPEHRLALRQVYAKTLPAFVQRLGILIARHLKRLERVILGYLEVSDGPEEEARLGILETLQCTIEHAWPRMPCRIPVLLKALLKMIWDVHTDQGSTPEPVRAALLQRATECLILLDRCSEGQVKILLEGVYSCCEENRVRECIRRVQENT", "length": 471, "header": "tr|A0A8V0ZA53-1|A0A8V0ZA53_CHICK Isoform 1 of TELO2 interacting protein 2 OS=Gallus gallus OX=9031 GN=TTI2 PE=3 SV=1 CANONICAL=A0A8V0ZA53-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53/entry#A0A8V0ZA53-1", "sequence": { "sequence": "MEPQPPAEQVLRQLGQLLSQRPGVVTELGALLEAAEPRWLLGAGSPAALGELAAALSAFAALPEREQDAAELRDGDGAYAAAAERAADVGRVFLRLLAKLEAAKAEESLGPAVEPVLRRVMGHIYVLAVTHLAEGAWSSAGSRAVAAELLAALVRAAGCGTVAELLRGRKEEEEGGFAAIMGLLRPRLGKDTWKCNPATKHVFSWTLLHITRPWLSQHLERVLPASLLISDDYREENKVLGVHCLHHIVLNVPGADLCQFNRAQVVYHALYNHLYSREAPLIQAVLLCLLDLLPVLERAQRQQPRPTSPCDEVLQLVLTHMEPEHRLALRQVYAKTLPAFVQRLGILIARHLKRLERVILGYLEVSDGPEEEARLGILETLQCTIEHAWPRMPCRIPVLLKALLKMIWDVHTDQGSTPEPVRAALLQRATECLILLDRCSEGQVKILLEGVYSCCEENRVRECIRRVQENT", "length": 471, "header": "tr|A0A8V0ZA53-1|A0A8V0ZA53_CHICK Isoform 1 of TELO2 interacting protein 2 OS=Gallus gallus OX=9031 GN=TTI2 PE=3 SV=1 CANONICAL=A0A8V0ZA53-1" }, "locus": { "chromosome": "22", "start_pos": 1777508, "end_pos": 1774113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042857.1", "url": "https://www.ensembl.org/id/ENSGALT00010042857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025347.1", "url": "https://www.ensembl.org/id/ENSGALP00010025347.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426923", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F592-1", "protein_name": "TELO2-interacting protein 2 isoform X1", "gene_name": "tti2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRELNIRDSTGFCSIHAALSHIQERFESEDTHDKRASILEDTIELLTGAPLDWLFPEVNADLRGQYLRLVNSFTCYAALPVCETDSGTLPAQSYESIPVKSQAVSAVLLALSAQIEKFLVKQNGASIKSLVRTLAPSLYIFAVTHLHKHPWTDGPSRKKASELLTALLRMTGSGSVQELLSGKPDVAKKGVFGPVLHTLQSELTQKNWKRNQAVKHVFSTTLVQVEQPWLTDYLENVFPPSLLISDDYHIENKILGVHCLHHIVLNVPAADLRQFNRAQVLYHTLFNHLYTSEAALVQVVLPCLIDLLPILEKSSAHASFPCISNRFDDLLCHILTYMEMEHKLDLRQVYAKNLVLLIDRMGISVIRHLKRLERVIVGYMEVSDAPEEKARLSILDALQKTLQIAWPRMEKRRDSLAQSLLRFLVDVSSDSSPTELKEQLMTKASHCLLLLVHCSKGKLQALLREVDSSCVPDPVFKCIQNVLAASCP", "length": 488 }, "evidence": [ { "id": "A0A8V0ZA53", "url": "https://omabrowser.org/oma/group/A0A8V0ZA53/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LRN2-1", "protein_name": "TELO2 interacting protein 2", "gene_name": "TTI2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPSSSQESAAGQGSLPAEWPSSALGQAFSQILHQFNSQESRRGKARNTVLQDLSALLEAKECDKLFEGSDNSLRGMPEILGQVAKALEKHAAPPREPEGRGDRHAEVAEKAAAVGLLFLKLLRKVEAARNSLVCPAWKTGLRHMAGSIYIFAVTHSSEQPWTSARSLVIAGQVLALLLQVTECGSVAGFLHGENEDDKGRFTAIMGLLKPELNKESWKNNPATKYVFSWTLQKVTRPWLSHHLERILPPSLLISDDYQTENKILGVHCLHHIVLNVPAADLLQYNRAQVLYHALFNHLYTPEHHLIQAVLLCLLDLFPILEKTLHWKGDAARPTTHCDEVLQLILTHMEPEHRLLLRRTYARNLPAFVKRLGILTVRHLKRLERVIISYLEVYDGPEEEARLKILETLKLLLQYTWPRVSCRLVVLLKALLKLICDVAGDSSLTPGPIKSTLLEEATDCLILLDHCSQGQVKGLLAKISQSCEDSKVMNCIRKVQQVSESTPYDAT", "length": 507 }, "evidence": [ { "id": "A0A8V0ZA53", "url": "https://omabrowser.org/oma/group/A0A8V0ZA53/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66H56-1", "protein_name": "TELO2-interacting protein 2", "gene_name": "Tti2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLGSTEEKSGGGCSLPTEVSPPALQQAFSKILHGLSRQESSGQGNAGNAALRDLGALIEATECDKLFEGTGGGGSPREMPEILGQVAKALEKFAAPKEKADGSEEHPEVPEKATEVGLLFLKLLGKVETAKSSPVCPAWKTGLRHLSGPTYIFAITHRLKQPWTSPKSQHVAGEVLSLLFRVTECSSVAEFLCGENKDDRGRFAVVLGLLKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLSQHLEKILPPSLLISDDYQTDNKVLGVQCLHHIVINVPAADLLQYNRAQVLYHALFNHLYMPEHRLIQAVLLCLLDLFPVLEKALHWQGEAARASTHCHEVLQLVLTHMESEHRLLLRRTYARNLPAFVKKLGILTARHLKRLEQVILGYLEVYDEPEDESRLKILETLKLVMQYTWPRIPCRVVVLLKALLKLICDIARDTIPTTEAAKSAVLQEATDCLILLDHCSQGQVKGLLANIALSCDDSTVVSCIRKVQGSAEAPGEDPGDD", "length": 511 }, "evidence": [ { "id": "A0A8V0ZA53", "url": "https://omabrowser.org/oma/group/A0A8V0ZA53/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NXR4-1", "protein_name": "TELO2-interacting protein 2", "gene_name": "TTI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEARRGNVKDAVLKDLGDLIEATEFDRLFEGTGARLRGMPETLGQVAKALEKYAAPSKEEEGGGDGHSEAAEKAAQVGLLFLKLLGKVETAKNSLVGPAWQTGLHHLAGPVYIFAITHSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSVILGLLKPDLYKESWKNNPAIKHVFSWTLQQVTRPWLSQHLERVLPASLVISDDYQTENKILGVHCLHHIVLNVPAADLLQYNRAQVLYHAISNHLYTPEHHLIQAVLLCLLDLFPILEKTLHWKGDGARPTTHCDEVLRLILTHMEPEHRLLLRRTYARNLPAFVNRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLMQHTWPRVSCRLVVLLKALLKLICDVARDPNLTPESVKSALLQEATDCLILLDRCSQGRVKGLLAKIPQSCEDRKVVNYIRKVQQVSEGAPYNGT", "length": 508 }, "evidence": [ { "id": "A0A8V0ZA53", "url": "https://omabrowser.org/oma/group/A0A8V0ZA53/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGV4-1", "protein_name": "TELO2-interacting protein 2", "gene_name": "Tti2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLDSAEEKSGVGCSLPAEGSPPALEPAFSKILNRLSRPKSSGQGGARNAALKDLGALIEAAEGDRFFEGSGSGGSLRGMPEILGQVVRALEKFAAPEEKADGVEEHPEVPEKATEVGSLFLKLLGKVEAAKSSPDCPAWKTGLRHMSGPVYIFAITHRLKQPWTSPASQHVAGEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGLLKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLNQHLEKILPPSLLISDDYQTENKILGVQCLHHIVVTVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKALHWKGDTARVTTHCHEVLQLILTHMEPEHRLLLRRTYARHLPAFVKRLGILTVRHLKRLEQVILGYLEVYDEPEDETRLKILETLKLVMQYTWPRIPCRVVVLLKALLKLICDISRDTIPTTEAAKSTMLQEATDCLILLDHCSQGQVKGLLAKIAVSCEDSTVVSCIRKVQQGSADSPGDDTEGD", "length": 512 }, "evidence": [ { "id": "A0A8V0ZA53", "url": "https://omabrowser.org/oma/group/A0A8V0ZA53/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA56-1", "uniprot_ac": "A0A8V0ZA56", "uniprot_id": "A0A8V0ZA56_CHICK", "mass": { "chemical_mass": 101943.0, "monoisotopic_mass": 101943.0 }, "refseq": { "ac": "XP_025009761", "name": "proprotein convertase subtilisin/kexin type 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009761" }, "gene_names": [ { "name": "PCSK6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA56" } ] }, { "name": "PCSK6", "type": "synonym", "evidence": [ { "id": "XP_025009761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009761" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA56/entry#names_and_taxonomy" } ] }, { "name": "proprotein convertase subtilisin/kexin type 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025009761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009761" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009761" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCSK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA56", "locus": { "chromosome": "10", "start_pos": 17646810, "end_pos": 17669696, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019081", "url": "https://www.ensembl.org/id/ENSGALG00010019081" } ] } } ], "crossref": [ { "id": "A0A8V0ZA56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA56", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395454", "url": "https://www.ncbi.nlm.nih.gov/gene/395454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395454", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395454", 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAA3-1", "uniprot_ac": "A0A8V0ZAA3", "uniprot_id": "A0A8V0ZAA3_CHICK", "mass": { "chemical_mass": 153138.0, "monoisotopic_mass": 153138.0 }, "refseq": { "ac": "XP_004943891", "name": "cell migration-inducing and hyaluronan-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943891" }, "gene_names": [ { "name": "CEMIP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ] }, { "name": "CEMIP", "type": "synonym", "evidence": [ { "id": "XP_004943891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943891" } ] } ], "protein_names": [ { "name": "hyaluronoglucosaminidase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.35", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3/entry#names_and_taxonomy" } ] }, { "name": "cell migration-inducing and hyaluronan-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943891" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943891.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943891" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEMIP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3", "locus": { "chromosome": "10", "start_pos": 12261137, "end_pos": 12359111, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019331", "url": "https://www.ensembl.org/id/ENSGALG00010019331" } ] } } ], "crossref": [ { "id": "cd13938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415476", "url": "https://www.ncbi.nlm.nih.gov/gene/415476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415476", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415476", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGRADED", "url": "https://omabrowser.org/oma/group/YGRADED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA93", "url": "https://www.orthodb.org/?gene=A0A8V0ZA93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2160916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2160916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPTSAYLAESLVFFLFVASFVSIAEAAVACPDKDPELEIWNPGHNQGNHIEIRNGRKLLLSSSATVHSIHIMDGGKLIIKDDVQPIILRTRYILIENDGELRIGSEMCPYQGNVVIILYGRADDGSEANPYFGRKYIGVSEGGTLEIHGKKKLSWTFLNKTLHPGGMEEGGYYFERSWGHRGVIVHVIDPKMGAVVHSDRFDTYRAKEESKRLAQYLDRVANGMILSVAVNDEGSRNLDDSARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHKGSAVAKVFKLFKAENGELFNVSSTSEWVQDVEWTEWFEKPEKARSKDMEKLSDFKAAHPDKICRQPIDIQAETLDGTILTTEVFYKNGQDYQFLCHGKDQTGEGCRNYRVRFLCGSSVKPKLTVTIDTNVNSTVLNLVDDVSSWEPGDRIVVASTDYSMYQAEEFQVLPCPSCRPTQVKVAGKAAYLHVGEVIDGVDMRAEVGLLSRNVVIMGEMEGQCYEYSSKLCSFFDFDTFGGHIKIGLDFKATHLEGLELKYMGQQTMGHYPIHFHMAGDVDEKGGYNPPTYVKDVSIHHTFSRCVTIHGSNGLLVKDVVGYDALGHCFFTEDGPEERNTFDHCLGLLVKPSTLLPSDRDSRMCKLITEGAYPGYIPKPRQDCSAVSTFWIANPHNNLINCAAAGSEETGFWFVLHHVPTGPSAGMYSPGYSEHMPMGRFSNNRAHSNYRAGMIIDNGVKTTPASAKDKRPILTLISGRYGPHKDADPLKPREPAIIERFIAYKNQDHGAWLRGGDVWLDNCQFADNGIGLTLASGGTFPHDDGSKQEIKNSLFVGESGNLGTEMMDNEIWGPGGLDHRGRTLPISPNFPIRGIQFYDGPINVQNCTFRKFAALDGRHTSALAFRLNNAWQSCPNNNVTDIHFEDVPITSRVFFGEPGPWFNDLDMDGDKTSVFHDVDGSVSEYPGSYLIKEDNWLIKHPDCIDVPDWRGSICSGHYAQIYIQAYKPANLKMKIIKNDYHNHPLYLEGALSKSTHYQQYQPVITLRKGYTIHWDKTAPEELTIWLINFNKNDWIQVGFCYPKGTTFSILSDIHNRLLKKTIKTGTFYRVSQMEKLEYRYPSKGYYYWDEDTGLLFLKLKAQNEKEKFAFCSVKGCERIRIKAMIPKTAGVSDCQATAYPKYIETPVVEVPMPKKLSSVQLKTKDHLLEVKIETYKKQYFHLKDDYAYIEVDGIRYFLTEEGIQLIVIDGHHGKVVDRVTFKNSILQGIPAQIENYVNNIKNHSIVLVTSKGRFISRGPWTKVLEKLGAEKGFSLKEKMAFVGFKGSFRPVWVKLVTNEDSAKIYQALPIPVVKKMKL", "length": 1360, "header": "tr|A0A8V0ZAA3-1|A0A8V0ZAA3_CHICK Isoform 1 of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP PE=3 SV=1 CANONICAL=A0A8V0ZAA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3/entry#A0A8V0ZA93-1", "sequence": { "sequence": "MAPPTSAYLAESLVFFLFVASFVSIEAAVACPDKDPELEIWNPGHNQGNHIEIRNGRKLLLSSSATVHSIHIMDGGKLIIKDDVQPIILRTRYILIENDGELRIGSEMCPYQGNVVIILYGRADDGSEANPYFGRKYIGVSEGGTLEIHGKKKLSWTFLNKTLHPGGMEEGGYYFERSWGHRGVIVHVIDPKMGAVVHSDRFDTYRAKEESKRLAQYLDRVANGMILSVAVNDEGSRNLDDSARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHKGSAVAKVFKLFKAENGELFNVSSTSEWVQDVEWTEWFEKPEKARSKDMEKLSDFKAAHPDKICRQPIDIQAETLDGTILTTEVFYKNGQDYQFLCHGKDQTGEGCRNYRVRFLCGSSVKPKLTVTIDTNVNSTVLNLVDDVSSWEPGDRIVVASTDYSMYQAEEFQVLPCPSCRPTQVKVAGKAAYLHVGEVIDGVDMRAEVGLLSRNVVIMGEMEGQCYEYSSKLCSFFDFDTFGGHIKIGLDFKATHLEGLELKYMGQQTMGHYPIHFHMAGDVDEKGGYNPPTYVKDVSIHHTFSRCVTIHGSNGLLVKDVVGYDALGHCFFTEDGPEERNTFDHCLGLLVKPSTLLPSDRDSRMCKLITEGAYPGYIPKPRQDCSAVSTFWIANPHNNLINCAAAGSEETGFWFVLHHVPTGPSAGMYSPGYSEHMPMGRFSNNRAHSNYRAGMIIDNGVKTTPASAKDKRPILTLISGRYGPHKDADPLKPREPAIIERFIAYKNQDHGAWLRGGDVWLDNCQFADNGIGLTLASGGTFPHDDGSKQEIKNSLFVGESGNLGTEMMDNEIWGPGGLDHRGRTLPISPNFPIRGIQFYDGPINVQNCTFRKFAALDGRHTSALAFRLNNAWQSCPNNNVTDIHFEDVPITSRVFFGEPGPWFNDLDMDGDKTSVFHDVDGSVSEYPGSYLIKEDNWLIKHPDCIDVPDWRGSICSGHYAQIYIQAYKPANLKMKIIKNDYHNHPLYLEGALSKSTHYQQYQPVITLRKGYTIHWDKTAPEELTIWLINFNKNDWIQVGFCYPKGTTFSILSDIHNRLLKKTIKTGTFYRVSQMEKLEYRYPSKGYYYWDEDTGLLFLKLKAQNEKEKFAFCSVKGCERIRIKAMIPKTAGVSDCQATAYPKYIETPVVEVPMPKKLSSVQLKTKDHLLEVKIETYKKQYFHLKDDYAYIEVDGIRYFLTEEGIQLIVIDGHHGKVVDRVTFKNSILQGIPAQIENYVNNIKNHSIVLVTSKGRFISRGPWTKVLEKLGAEKGFSLKEKMAFVGFKGSFRPVWVKLVTNEDSAKIYQALPIPVVKKMKL", "length": 1359, "header": "tr|A0A8V0ZA93-1|A0A8V0ZAA3_CHICK Computationally mapped isoform of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP PE=3 SV=1 CANONICAL=A0A8V0ZAA3-1" }, "locus": { "chromosome": "10", "start_pos": 12308766, "end_pos": 12261373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046767.1", "url": "https://www.ensembl.org/id/ENSGALT00010046767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027845.1", "url": "https://www.ensembl.org/id/ENSGALP00010027845.1" } ] } }, { "isoform_ac": "A0A8V0ZAA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3/entry#A0A8V0ZAA3-1", "sequence": { "sequence": "MAPPTSAYLAESLVFFLFVASFVSIAEAAVACPDKDPELEIWNPGHNQGNHIEIRNGRKLLLSSSATVHSIHIMDGGKLIIKDDVQPIILRTRYILIENDGELRIGSEMCPYQGNVVIILYGRADDGSEANPYFGRKYIGVSEGGTLEIHGKKKLSWTFLNKTLHPGGMEEGGYYFERSWGHRGVIVHVIDPKMGAVVHSDRFDTYRAKEESKRLAQYLDRVANGMILSVAVNDEGSRNLDDSARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHKGSAVAKVFKLFKAENGELFNVSSTSEWVQDVEWTEWFEKPEKARSKDMEKLSDFKAAHPDKICRQPIDIQAETLDGTILTTEVFYKNGQDYQFLCHGKDQTGEGCRNYRVRFLCGSSVKPKLTVTIDTNVNSTVLNLVDDVSSWEPGDRIVVASTDYSMYQAEEFQVLPCPSCRPTQVKVAGKAAYLHVGEVIDGVDMRAEVGLLSRNVVIMGEMEGQCYEYSSKLCSFFDFDTFGGHIKIGLDFKATHLEGLELKYMGQQTMGHYPIHFHMAGDVDEKGGYNPPTYVKDVSIHHTFSRCVTIHGSNGLLVKDVVGYDALGHCFFTEDGPEERNTFDHCLGLLVKPSTLLPSDRDSRMCKLITEGAYPGYIPKPRQDCSAVSTFWIANPHNNLINCAAAGSEETGFWFVLHHVPTGPSAGMYSPGYSEHMPMGRFSNNRAHSNYRAGMIIDNGVKTTPASAKDKRPILTLISGRYGPHKDADPLKPREPAIIERFIAYKNQDHGAWLRGGDVWLDNCQFADNGIGLTLASGGTFPHDDGSKQEIKNSLFVGESGNLGTEMMDNEIWGPGGLDHRGRTLPISPNFPIRGIQFYDGPINVQNCTFRKFAALDGRHTSALAFRLNNAWQSCPNNNVTDIHFEDVPITSRVFFGEPGPWFNDLDMDGDKTSVFHDVDGSVSEYPGSYLIKEDNWLIKHPDCIDVPDWRGSICSGHYAQIYIQAYKPANLKMKIIKNDYHNHPLYLEGALSKSTHYQQYQPVITLRKGYTIHWDKTAPEELTIWLINFNKNDWIQVGFCYPKGTTFSILSDIHNRLLKKTIKTGTFYRVSQMEKLEYRYPSKGYYYWDEDTGLLFLKLKAQNEKEKFAFCSVKGCERIRIKAMIPKTAGVSDCQATAYPKYIETPVVEVPMPKKLSSVQLKTKDHLLEVKIETYKKQYFHLKDDYAYIEVDGIRYFLTEEGIQLIVIDGHHGKVVDRVTFKNSILQGIPAQIENYVNNIKNHSIVLVTSKGRFISRGPWTKVLEKLGAEKGFSLKEKMAFVGFKGSFRPVWVKLVTNEDSAKIYQALPIPVVKKMKL", "length": 1360, "header": "tr|A0A8V0ZAA3-1|A0A8V0ZAA3_CHICK Isoform 1 of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP PE=3 SV=1 CANONICAL=A0A8V0ZAA3-1" }, "locus": { "chromosome": "10", "start_pos": 12308766, "end_pos": 12261373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046782.1", "url": "https://www.ensembl.org/id/ENSGALT00010046782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027855.1", "url": "https://www.ensembl.org/id/ENSGALP00010027855.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415476", "resource": "KEGG Pathway" }, { "id": "R-GGA-2160916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2160916", "resource": "Reactome", "description": "Hyaluronan degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R512-1", "protein_name": "hyaluronoglucosaminidase", "gene_name": "CEMIP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGAAHRPDVSFKAMLTISWFILARFPEPASTVAAECPDQWPELQPWNPGHDPDHCVYIGQGRTLLLTSSATVQSIHISEGGKLVIKDQNEAIVLRTRHILIDNGGEMHVGSALCPFQGHFSIVLYGRADEGTQPNPYFGLKYIGVDKGGTLELHGQKKLSWTFLNKTLHPGGMEEGGYFFERTWGHRGIIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDMARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHRGSAAARVFKLFQTEHGEHFNVSSSSEWVQDVEWTEWFEHDQVSYAKGGEKISDLRAVHPGKICNRPIDIQATTVDGVNLTTEVVYKRGQDYKFVCYDRGQACQSYRVRFLCGKPVRPKLTVTIDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCKACASNQVKVAGKPMYLHIGEEIDGVDMRAEVGLLSRNIVVMGEMEDKCYPYSDHICDFFDFDTFGGHIKFALGFKAAHMEGVELKHMGQQLVGQYPIHFHLVGDVDERGGYDPPTYIKGLSIHHTFSRCVTVHGSNGLLVKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITQDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSAGKYSPGYSEHVPLGKFHNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLAIISARYSPHQDADPLKPREPAIIKHFTAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQFYDGPINVQNCTFRKFAALEGRHTSALAFRLNNAWQSCPHNNVTNIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDVDGSVSEYPGSYLTKDDNWLVRHPDCINVPDWRGAICSGRYAQMYIQAFKTSNLRMKIIKNDFPGHPLYLEGALTRSTHYQQYQPVITLQKGYTIHWDQTAPAELTIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFMRTSQMEKVEQSHSGRSHYYWDEDSGLLFLKLKAQNERERFAFCSMKGCERIKIKALIPKNAGISDCTASAYPKFTEKAIVDVPMPKKLLGSQLKTKDHFLEVKMESSKQRFFHLLNDFAYIEVEGKRYPLVEDGIQVVVIDGRHGHVASQASFRNAILQGIPRQLFNYMAAIPDNSIVLVASKGRYVSRGPWTRVLENLGADKGVKLKEQMAFVGFKGSFRPTWVTLDTEDHGAKIFQVVPIPVVRKKKL", "length": 1361 }, "evidence": [ { "id": "A0A8V0ZAA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZWI0-1", "protein_name": "hyaluronoglucosaminidase", "gene_name": "Cemip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRQLSGSGLRLPERPPEPARVQPRRPPTSELNAWDQIPDSGMLYSRPPRRGRISVINLREQGVGMRAAGSHNVSLKIVLAMGCLLLVGFSGAASAVTTECPDQSPELQPWSPGHDRNHQVHIGHGRKLLLTSSATVHSITISGGGKLVIKDRHEHIVLRTRHILIDDGGELHAGSALCPFEGNFSIVLYGRADESIPPDPYYGLKYIGVGKGGTLELHGQKKLSWTFLNKTLHPGGMQEGGYFFERSWGHRGVIVHVIDAKLGTVVHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDTARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHKGSAAARVFKLFQTEHGEHFNVSSSSEWVQDVEWTEWFNHDKVPQSKGGEKISDLRAAYPGKICNRPIDIQATTMDGVALSTEVVYKNGQDYRFACYTRGRACRNYRVRFLCGKPVRPKLTVSIDTNVNSTILSLVDNVRSWRPGDTLVVASTDYSMYQAEEFQVLPCKACTSTQVKVAGKPQYLHIGEEIDGVDMRAEVGLLTRNIVVMGEMEDRCYPYSHHICDFFDFDTFGGHIKFALGFKATHLEGVELKYMGQQLVGQYPIHFHLAGDLDEQGGYDPPTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSRMCKVITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSIISARYSPHQDADPLKPREPAIIRHFTAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQFYDGPINIQNCTFRKFAALEGRHTSALAFRLNNAWQSCPHNNVTNIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDLDGSVSEYPGSYLTKDDNWLVRHPDCINVPDWRGAICSGRYAQMYIQAYKSSNLRMKIIKNDFPSHPLYLEGALTRSTHYQQYQPVITLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGTFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALLPRNAGISDCTATAYPRFTERAVVDVPMPRKLFGAQLKTKDHFLEVKMESSRQHFFHLRNDFAYIEVDGRRYPCSEDGIQIVVIDGSRGHVVSLGSFRNAILQGIPWQLFNYVAAIPDNSIVLMASKGRYITRGPWTRVLEKLGADKGLKLKEKMTFVGFKGNFRPIWVTLETEDHKAKIFQVVPIPVVRKKKL", "length": 1427 }, "evidence": [ { "id": "A0A8V0ZAA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BI06-1", "protein_name": "Cell migration-inducing and hyaluronan-binding protein", "gene_name": "Cemip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASGRHDVSLKIVLATGCLLLANFSGASSAVATECPDQSPELQPWSPGHNRDYQVHIGHGRKLLLTSSATVHSITISGGGKLVIKDHHEHIVLRTRYILIDDGGELHAGSALCPFEGNFSIVLYGRADENILPDPYYGLKYIGVDKGGTLELHGQKKLSWTFLNKTLHPGGMQEGGYFFERSWGHRGVIVHVIDAKLGTVVHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDTARKAMTKLGSKHFLHLGFRHPWSFITVKGNPSSSVEDHIEYHGHKGSAAARVFKLFQTEHGEHFNVSSSSEWVQDVEWTEWFDHDKVPQSKGGEKISDLRAAYPGKICNRPIDIQATTMDGVALSTEVVYKNGQDYRFACYTRGRACRSYRVRFLCGKPVRPKLTVSIDTNVNSTILSLVDNVRSWRPGDTLVVASTDYSMYQAEEFRVLPCKACTSTQVKVAGKPQYLHIGEEIDGVDMRAEVGLLTRNIVVMGEMEDRCYPYTNHICDFFDFDTFGGHIKFALGFKAAHLEGVELKYMGQQLVGQYPIHFHLAGDLDEQGGYDPPTYIRDLSIHHTFSRCITVHGSNGLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSRMCKVITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSIISARYSPHQDADPLKPREPAIIRHFTAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQFYDGPINIQNCTFRKFAALEGRHTSALAFRLNNAWQSCPHNNVTNIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDLDGSVSEYPGSYLTKDDNWLVRHPDCINVPDWRGAICSGRYAQMYIQAYKSSNLRMKIIKNDFPSHPLYLEGALTRSTHYQQYQPVITLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGTFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALLPRNAGISDCTATAYPRFTERAIVDVPMPRKLFGAQLKTKDHFLEVKMESSRQHFFHLRNDFAYIEVDGRRYPCSEDGIQIVVIDGSRGHVVSHGSFRNAILQGIPWQLFNYVAAIPDNSIVLMASKGRYITRGPWTRVLEKLGADKGLKLKEKMAFVGFKGSFRPIWVTLETEDHKAKIFQVVPIPVVRKKKL", "length": 1361 }, "evidence": [ { "id": "A0A8V0ZAA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUJ3-1", "protein_name": "Cell migration-inducing and hyaluronan-binding protein", "gene_name": "CEMIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAGRQDFLFKAMLTISWLTLTCFPGATSTVAAGCPDQSPELQPWNPGHDQDHHVHIGQGKTLLLTSSATVYSIHISEGGKLVIKDHDEPIVLRTRHILIDNGGELHAGSALCPFQGNFTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYFFERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHIEYHGHRGSAAARVFKLFQTEHGEYFNVSLSSEWVQDVEWTEWFDHDKVSQTKGGEKISDLWKAHPGKICNRPIDIQATTMDGVNLSTEVVYKKGQDYRFACYDRGRACRSYRVRFLCGKPVRPKLTVTIDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHIGEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAHLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSIISARYSPHQDADPLKPREPAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVALEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMKIIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPKKLFGSQLKTKDHFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGIQVVVIDGNQGRVVSHTSFRNSILQGIPWQLFNYVATIPDNSIVLMASKGRYVSRGPWTRVLEKLGADRGLKLKEQMAFVGFKGSFRPIWVTLDTEDHKAKIFQVVPIPVVKKKKL", "length": 1361 }, "evidence": [ { "id": "A0A8V0ZAA3", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "clathrin-coated endocytic vesicle", "id": "GO:0045334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "hyalurononglucosaminidase activity", "id": "GO:0004415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004415", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "ER retention sequence binding", "id": "GO:0046923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" }, { "name": "hyaluronan catabolic process", "id": "GO:0030214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1284, "end_pos": 1286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5693356", "name": "CEMIP hydrolyzes HA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZAA3-1" ], "evidence": [ { "id": "R-GGA-5693356", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693356" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZAA3", "gene_name": "CEMIP", "activity": [ { "ec_number": "3.2.1.35", "activity": "Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.", "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ] }, { "ec_number": "3.2.1.35", "activity": "", "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA3" }, { "id": "PS51484", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51484" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G8", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 162, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.35", "ec_name": "Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.", "evidence": [ { "id": "3.2.1.35", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.35" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1284, "end_pos": 1286 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 888, "end_pos": 890 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"MEQDTKEEVSEKPKPAPSAEKFGWIKKSSGGLLGLWKDRYVQLRKTQLVVYEDEAFRRRLFLVLKCHEECKNTEMKSQSQDEQKCIETVELESYDKCQELRALLKKKNRFILIRSPGKKVHDIKFQAPTSEEKESWIKALNEGINRGKNKIFDEVKVDESLSLDHVTRDRVKVAHGRRPPTRSHLKEAAKSTSDGILRLDLDIVDNGPPNFDSTVSENENPPPQKETPKPPMPPTKPSGTKENHDAENSVSDQEHKMSPPLPPDKKLKEGLASKDNANAREEDCVSREESVEESSTPGEENTDQLVEISNKGTAKAPIPLPKSVPDKLKVAWDQPVLEPKNANDLESSGDSSKGSLAAIATSDVAKPPVPPPKVLSEKMIATMNSGHSDLEDGGLEELRSGSSKSPVNGIEDGEAAESASQTAETEEGNGRTSTEREQQTSAEQRESSLATESGHESVKGTIEKKISVETPAALKLRSSSLGDLLSDSKSTQRALPHQGLAEDSHYCLAKMEKKVANEREKAEKLLQKVLREGLEQAQEGNGPPVVAETLLNEAVEQLRQATQVLQEIKSLGELKKEATQKQKEKQKDLVTLYRRSAP", "length": 598, "header": "tr|A0A8V0ZAA0-1|A0A8V0ZAA0_CHICK Isoform 1 of Pleckstrin homology domain containing O2 OS=Gallus gallus OX=9031 GN=PLEKHO2 PE=1 SV=1 CANONICAL=A0A8V0ZAA0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA0/entry#A0A8V0Z2W5-1", "sequence": { "sequence": 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homology domain containing O2 OS=Gallus gallus OX=9031 GN=PLEKHO2 PE=1 SV=1 CANONICAL=A0A8V0ZAA0-1" }, "locus": { "chromosome": "10", "start_pos": 17705552, "end_pos": 17681999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046295.1", "url": "https://www.ensembl.org/id/ENSGALT00010046295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027571.1", "url": "https://www.ensembl.org/id/ENSGALP00010027571.1" } ] } }, { "isoform_ac": "A0A8V0ZG92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA0/entry#A0A8V0ZG92-1", "sequence": { "sequence": "MEQDTKEEVSEKPKPAPSAEKFGWIKKSSGGLLGLWKDRYVQLRKTQLVVYEDEVHDIKFQAPTSEEKESWIKALNEGINRGKNKIFDEVKVDESLSLDHVTRDRVKVAHGRRPPTRSHLKEAAKSTSDGILRLDLDIVDNGPPNFDSTVSENENPPPQKETPKPPMPPTKPSGTKENHDAENSVSDQEHKMSPPLPPDKKLKEGLASKDNANAREEDCVSREESVEESSTPGEENTDQLVEISNKGTAKAPIPLPKSVPDKLKVAWDQPVLEPKNANDLESSGDSSKGSLAAIATSDVAKPPVPPPKVLSEKMIATMNSGHSDLEDGGLEELRSGSSKSPVNGIEDGEAAESASQTAETEEGNGRTSTEREQQTSAEQRESSLATESGHESVKGTIEKKISVETPAALKLRSSSLGDLLSDSKSTQRALPHQGLAEDSHYCLAKMEKKVANEREKAEKLLQKVLREGLEQAQEGNGPPVVAETLLNEAVEQLRQATQVLQEIKSLGELKKEATQKQKEKQKDLVTLYRRSAP", "length": 533, "header": "tr|A0A8V0ZG92-1|A0A8V0ZG92_CHICK Computationally mapped isoform of Pleckstrin homology domain containing O2 OS=Gallus gallus OX=9031 GN=PLEKHO2 PE=1 SV=1 CANONICAL=A0A8V0ZAA0-1" }, "locus": { "chromosome": "10", "start_pos": 17705552, "end_pos": 17681999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046317.1", "url": "https://www.ensembl.org/id/ENSGALT00010046317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027584.1", "url": "https://www.ensembl.org/id/ENSGALP00010027584.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "macrophage apoptotic process", "id": "GO:0071888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 145, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAA7-1", "uniprot_ac": "A0A8V0ZAA7", "uniprot_id": "A0A8V0ZAA7_CHICK", "mass": { "chemical_mass": 32148.0, "monoisotopic_mass": 32148.0 }, "refseq": { "ac": "XP_001235310", "name": "transmembrane protein 158", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235310" }, "gene_names": [ { "name": "TMEM158", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7" } ] }, { "name": "TMEM158", "type": "synonym", "evidence": [ { "id": "XP_001235310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235310" } ] } ], "protein_names": [ { "name": "Transmembrane protein 158", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 158", "type": "synonym", "evidence": [ { "id": "XP_001235310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235310" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001235310.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001235310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235310" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM158", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7", "locus": { "chromosome": "2", "start_pos": 42948701, "end_pos": 42943136, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019682", "url": "https://www.ensembl.org/id/ENSGALG00010019682" } ] } } ], "crossref": [ { "id": "A0A8V0ZAA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "776186", "url": "https://www.ncbi.nlm.nih.gov/gene/776186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776186", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACLPPCQ", "url": "https://omabrowser.org/oma/group/ACLPPCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAA7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38324:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38324:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001235310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPLLLPALLAACLPPCQGWSPSAAAGGQEEQELFSPPANSSRSPAGLEMDLDGAASKEDGGTASPGTPATPSREPSPSAPTSAGQQQQQQQQPRLQQPQLAEDPHCNISVQRQMLSSLLVRWSRPLGIQCDLLLFSTNSHGRAFFSAAFHRVGPPLVIDHLGLAAGGAQQDLRLCVGCSWVRGRRVGRLRGSAPQPQPQHQPAASSLSYPPAAEPGQYWLQGEPLNFCCLDFSLEELKGEPGWRMNRKPIESTLVACFMTLVIIVWSVAALIWPVPIIAGFLPNGMEQRRSAGTAAAANK", "length": 301, "header": "tr|A0A8V0ZAA7-1|A0A8V0ZAA7_CHICK Isoform 1 of Transmembrane protein 158 OS=Gallus gallus OX=9031 GN=TMEM158 PE=4 SV=1 CANONICAL=A0A8V0ZAA7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7/entry#A0A8V0ZAA7-1", "sequence": { "sequence": "MLPLLLPALLAACLPPCQGWSPSAAAGGQEEQELFSPPANSSRSPAGLEMDLDGAASKEDGGTASPGTPATPSREPSPSAPTSAGQQQQQQQQPRLQQPQLAEDPHCNISVQRQMLSSLLVRWSRPLGIQCDLLLFSTNSHGRAFFSAAFHRVGPPLVIDHLGLAAGGAQQDLRLCVGCSWVRGRRVGRLRGSAPQPQPQHQPAASSLSYPPAAEPGQYWLQGEPLNFCCLDFSLEELKGEPGWRMNRKPIESTLVACFMTLVIIVWSVAALIWPVPIIAGFLPNGMEQRRSAGTAAAANK", "length": 301, "header": "tr|A0A8V0ZAA7-1|A0A8V0ZAA7_CHICK Isoform 1 of Transmembrane protein 158 OS=Gallus gallus OX=9031 GN=TMEM158 PE=4 SV=1 CANONICAL=A0A8V0ZAA7-1" }, "locus": { "chromosome": "2", "start_pos": 42944189, "end_pos": 42943287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047501.1", "url": "https://www.ensembl.org/id/ENSGALT00010047501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028126.1", "url": "https://www.ensembl.org/id/ENSGALP00010028126.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:776186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776186", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2VDX9-1", "protein_name": "Transmembrane protein 158", "gene_name": "TMEM158", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPLLAALLAAACPLPPARGGAVDAPGLLGAPLNASVNASSSDEPAAPRLLASAAPGAPERPEEEAAAPCNISVQRQMLSSLLVRWGRPRGFQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRRPGRLRPTGATAGAPTALPAYPAAEPPGPLWLQGEPLHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTASAAAAAPAAVPAGTTAAAAAAAAAAAAAAAVTSGTATK", "length": 291 }, "evidence": [ { "id": "A0A8V0ZAA7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LSN8-1", "protein_name": "Transmembrane protein 158", "gene_name": "TMEM158", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLLAALLAVACPLPPARGGAADTSGLLGAPPNASVNASSAGEPAAPRLLASAAPGAPEHPGPEEEVAAAPCNISVQRQMLSSLLVRWGRPRGFQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRRPGRLRAAGATAGAPTALPSYPAAEPPGPLWLQGEPLHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTASTAAAAPAAVPAGTTTAAAAAAAAAAAAAAAVTSGAATK", "length": 295 }, "evidence": [ { "id": "A0A8V0ZAA7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8WZ71-1", "protein_name": "Transmembrane protein 158", "gene_name": "TMEM158", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPLLAALLAAACPLPPVRGGAADAPGLLGVPSNASVNASSADEPIAPRLLASAAPGPPERPGPEEAAAAAAPCNISVQRQMLSSLLVRWGRPRGFQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRRTGRLRPAAAPSAAAATAGAPTALPAYPAAEPPGPLWLQGEPLHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTASTTAATPAAVPAGTTAAAAAAAAAAAAAAVTSGVATK", "length": 300 }, "evidence": [ { "id": "A0A8V0ZAA7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XV7-1", "protein_name": "Transmembrane protein 158", "gene_name": "Tmem158", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPLLAALLAAACPLPPARGGATDAPGLSGTPPNASANASFTGEHSTPRLLASAASAPPERAGPEEAPAAPCNISVQRQMLSSLLVRWGRPRGLQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRLRAPAGAPTALPAYPAAEPGPLWLQGEPRHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTAGAPAAAPAAVPAGTTAAAAAAAAAAAAAAAVTSGVAPK", "length": 285 }, "evidence": [ { "id": "A0A8V0ZAA7", "url": "https://omabrowser.org/oma/group/A0A8V0ZAA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 71 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAD1-1", "uniprot_ac": "A0A8V0ZAD1", "uniprot_id": "A0A8V0ZAD1_CHICK", "mass": { "chemical_mass": 65572.0, "monoisotopic_mass": 65572.0 }, "refseq": { "ac": "XP_015150221", "name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150221" }, "gene_names": [ { "name": "PIGQ", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1" } ] }, { "name": "PIGQ", "type": "synonym", "evidence": [ { "id": "XP_015150221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150221" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol glycan anchor biosynthesis class Q", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015150221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150221" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150221.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150221" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGQ", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1", "locus": { "chromosome": "14", "start_pos": 13540128, "end_pos": 13506999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019684", "url": "https://www.ensembl.org/id/ENSGALG00010019684" } ] } } ], "crossref": [ { "id": "A0A8V0ZAD1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "770171", "url": "https://www.ncbi.nlm.nih.gov/gene/770171", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770171", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770171", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKGDKQN", "url": "https://omabrowser.org/oma/group/HKGDKQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4H2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAB2", "url": "https://www.orthodb.org/?gene=A0A8V0ZAB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAD1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAD5", "url": "https://www.orthodb.org/?gene=A0A8V0ZAD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZHT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21329:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21329:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015150221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQINPLSYGSVVQTYRLPTYSCYPKDSWTSLCKKLFLGELIYPWKHKGEKQD", "length": 573, "header": "tr|A0A8V0ZAD1-1|A0A8V0ZAD1_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0Z4H2-1", "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRYLGDSQEAYFSDLSDHQSAKGWAPGDRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQKTP", "length": 553, "header": "tr|A0A8V0Z4H2-1|A0A8V0Z4H2_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13535698, "end_pos": 13511176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047520.1", "url": "https://www.ensembl.org/id/ENSGALT00010047520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028134.1", "url": "https://www.ensembl.org/id/ENSGALP00010028134.1" } ] } }, { "isoform_ac": "A0A8V0ZAB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0ZAB2-1", "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQKTP", "length": 526, "header": "tr|A0A8V0ZAB2-1|A0A8V0ZAD1_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13535698, "end_pos": 13511176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047511.1", "url": "https://www.ensembl.org/id/ENSGALT00010047511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028131.1", "url": "https://www.ensembl.org/id/ENSGALP00010028131.1" } ] } }, { "isoform_ac": "A0A8V0ZAC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0ZAC1-1", "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQLHPCRHPSLVLPLSMGTGELKQESRKLVTQESMGTGEQKTGHSSVGKRKIQLLKKQCLCACFYCLCLFCD", "length": 593, "header": "tr|A0A8V0ZAC1-1|A0A8V0ZAC1_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13537741, "end_pos": 13511176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047530.1", "url": "https://www.ensembl.org/id/ENSGALT00010047530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028141.1", "url": "https://www.ensembl.org/id/ENSGALP00010028141.1" } ] } }, { "isoform_ac": "A0A8V0ZAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0ZAD1-1", "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQINPLSYGSVVQTYRLPTYSCYPKDSWTSLCKKLFLGELIYPWKHKGEKQD", "length": 573, "header": "tr|A0A8V0ZAD1-1|A0A8V0ZAD1_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13538984, "end_pos": 13511176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047545.1", "url": "https://www.ensembl.org/id/ENSGALT00010047545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028151.1", "url": "https://www.ensembl.org/id/ENSGALP00010028151.1" } ] } }, { "isoform_ac": "A0A8V0ZAD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0ZAD5-1", "sequence": { "sequence": "MDTALETSQQKEKLLKALYTLQLKSNTTLQTASPLLSSQQGMGMVTELQVQQLADKTKTLCRDLDDIKNLLHYRQDELVRQIPNPTGSRYGCVSGIHCSRDGSIYVTAEAAPWVHVLSSTGQVLRSLPCWQTGREGGSFLPEDVTVTRAGMVAVADMINGAVWVFNPHTTPSKGEWIKIGKLGSPRGVGVDSTGKILVADYAQGQVCSFALDHAFRTLNICSVPNLQGPRYVSPAPNGGFVVSRPPRIAGMVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQINPLSYGSVVQTYRLPTYSCYPKDSWTSLCKKLFLGELIYPWKHKGEKQD", "length": 823, "header": "tr|A0A8V0ZAD5-1|A0A8V0ZAD5_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13538984, "end_pos": 13507015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047550.1", "url": "https://www.ensembl.org/id/ENSGALT00010047550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028156.1", "url": "https://www.ensembl.org/id/ENSGALP00010028156.1" } ] } }, { "isoform_ac": "A0A8V0ZHT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1/entry#A0A8V0ZHT5-1", "sequence": { "sequence": "MVLKVFFPSCCSSAESGILIGRWIPEQSSAVILAVVHFPFIPVQVKQYLREVQQVTKVSVSVLGSWNNSKQEKEESLSEFLEDLGTIFSHEPWIQISKEGDSKFWNCSTLQKQPDNHREEEIILVYYDQRKVMLSHLHPPSDTADLGAEDASKLSAIFNTVASSKVLFMTDRYDDGPIKMTHWQSDGIEASIIVELMKQASVPACMLLTFLLSLVSGVCNSRVLKFWPLSFLWSKLSTCEQLGHRLQHLQVISSSKKAQNQTQLMRKANIFVSLLIDVALGILLMSWLYRKNQIGHLADTLIPVADHVAEELQDLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEMILWYVGLSACLGLTVALCILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLCLLVVIVQGLIHLLVDLIDSLPLYSIILRFCRSYRLAAGVKFRVLEQQDGKPLRLLMQLHPCRHPSLVLPLSMGTGELKQESRKLVTQESMGTGEQKTGHSSVGKRKIQLLKKQCLYQPSVLWQCGADIQAADLQLLP", "length": 603, "header": "tr|A0A8V0ZHT5-1|A0A8V0ZHT5_CHICK Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Gallus gallus OX=9031 GN=PIGQ PE=4 SV=1 CANONICAL=A0A8V0ZAD1-1" }, "locus": { "chromosome": "14", "start_pos": 13538899, "end_pos": 13511176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047536.1", "url": "https://www.ensembl.org/id/ENSGALT00010047536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028145.1", "url": "https://www.ensembl.org/id/ENSGALP00010028145.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770171", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770171", "resource": "KEGG Pathway" }, { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QHT3-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X1", "gene_name": "pigq", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLKIFFPQCCNTADSGLLVGRWIPGHNSAVVLAVVHYPFIPGQVKKYLSEIQSQTQVDLAVLGSWSMPKEGQEGLDSFLKDLSTIFPQKCWLQLSREIGKRGFTCRVVQNNGMLLQDKEQKSDVDGSEEDKIILVHYDQRKVMLSQLHPVQEADQKSEIEPSELRLVFQTVAQSQPLFFLDKYDDGPLKLTHWQSEGREASIIAELLKQASVPVCICLTWLLSLWLWFCSFRILNIPPVKFITSKLSTCVQSGYRAVHFKTVFSPKKADTHMDFMRKANIFVSFLVDIAFGLLLISWLYRENRISKLANTLVPVADHVAKELQQLLEWLMGAPAGLKMNKALDQVLGRFFLYHIHLWISYIHLMSPFIERILWYVGLSACLGLTFALSILSDIVALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLVVVLFQGVIHLSVDFINSFPLFAIGLRICRPYRLAEGVKFKVLCEESGSPLHLMMEINPLKCSSVLQRYRTPTYSCYPKDSWAALCKKLFVGELIYPWKQKTDKTD", "length": 584 }, "evidence": [ { "id": "A0A8V0ZAD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HBT3-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "gene_name": "Pigq", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLKAFFPTCCASADSGLLVGRWIPEQNSAVILAVAHFPFIPIQVKELLAQVHKASQVQVAVLGTWCHRRQEPEESLGHFLEGLGAIFSHDPWLQLCRERGTRFWSCKATYHQLQGTPTEDQVMLIFYDQRKLLLSWLHPPTALPDCQAGETTASTGGLADIFDTVAHSEVLFRNDQFDEGPVRLSHWQSEGMEASILVELAKQASGPVCLLMASLLSLLSAASACRLWKLWPLAFIRSKLSTCEQLQHRLKHLSFIFSTQKAQSPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSILSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEQEAGRPLRLLMQINPLPYSHVVHTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQREDKQD", "length": 578 }, "evidence": [ { "id": "A0A8V0ZAD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q642B8-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class Q", "gene_name": "Pigq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLKAFFPTCCASADSGLLVGRWVPGQNSAVILAVVHFPFIPIQVKELLAQVQKASQVQVTVLGTWCHRQQEPEESLGKFLEGLGAIFSHNPWLQLCREKGTRFWSCKATYHQMSSTLDTPTEDQVMLIFYDQRKLLLSWLHPPPVLPDCQIGDSTASTGGLADIFDTVARSEVLFRNDQFDEGPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLGPLAFIRSKLSTCEQLQHRLKHLSFIFSTEKAQSPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEKEAGRPLRLLMQINPLPYSHVVHTYRLPSCGCHPKHSWGTLCRKLFFGELIYPWRQREDKQD", "length": 581 }, "evidence": [ { "id": "A0A8V0ZAD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BRB3-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "gene_name": "PIGQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLKAFFPTCCVSTDSGLLVGRWVPEQSSAVVLAVLHFPFIPIQVKQLLAQVRQASQVGVAVLGTWCHCRQEPEESLGRFLESLGAVFPHEPWLRLCRERGGTFWSCEATHRQAPTAPGAPGEDQVMLIFYDQRQVLLSQLHLPTVLPDRQAGATTASTGGLAAVFDTVARSEVLFRSDRFDEGPVRLSHWQSEGVEASILAELARRASGPICLLLASLLSLVSAVSACRVFKLWPLSFLGSKLSTCEQLRHRLEHLTLIFSTRKAENPAQLMRKANTVASVLLDVALGLMLLSWLHGRSRIGHLADALVPVADHVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFVEHILWHVGLSACLGLTVALSLLSDIIALLTFHIYCFYVYGARLYCLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLLVVAVQGLIHLLVDLINSLPLYSLGLRLCRPYRLADKPTALQPRGAHLPPPQLWLPPQALLGRPVPQAVPWGAHLPLEAERGQAGLRELLARLAPPHGHSQPSALPGWHQLSWRMSCALWTLLCAPEHGRPCYHTLGLEVIGSEQMWGWPARLAALHHWHCLPWDPLPTCCGHHGGEHSNPRCPEHCPMPTLCTQVQRVRPPQQPQVEGWSPWGLPSGSALAVGVEGPCQDEPPSPRHPLAPSAEQHPASGGLKQSLTPVPSGPGPSLPEPHGVYLRMFPGEVAL", "length": 760 }, "evidence": [ { "id": "A0A8V0ZAD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYT7-1", "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "gene_name": "Pigq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLKVFFPTCCASADSGLLVGRWVPGQSSAVILAVVHFPFIPIQVKELLAQVQKASQVPVAVLGTWCHRQQEPQESLGNFLEGLGTIFSHDPWLQLCRERGTRLWSCKATYPQMSNPLDMHPEEQVMLIFYDQRKLLLSWLHPPPVLPACQMGDTTASTGGLADIFDTVARSEVLFRNDQFDERPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLWPLSFIRSKLSTCEQLHHRLKHLSFIFSTEKAQNPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEKEAGRPLRLLMQINPLSYNHVMHIYRLPRCGCHPKHSWGTLCRKLVFGELIYPWRQREDKQD", "length": 581 }, "evidence": [ { "id": "A0A8V0ZAD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", 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[ { "database": "UniProtKB", "id": "A0A8V0ZAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol N-acetylglucosaminyltransferase activity", "id": "GO:0017176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", 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"expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZAC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZAC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KTRCSSGSLEGYELKASLPPSVCNLVLYQNSSSSLVSTATPCMASSLFLHSRAPCRSPISMLFPKVFFQVNFLWGSSMAAQL", "length": 82, "header": 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"orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAC9-1", "uniprot_ac": "A0A8V0ZAC9", "uniprot_id": "A0A8V0ZAC9_CHICK", "mass": { "chemical_mass": 81432.0, "monoisotopic_mass": 81432.0 }, "refseq": { "ac": "NP_001186348", "name": "uncharacterized protein KIAA1841 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186348" }, "gene_names": [ { "name": "KIAA1841", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9" } ] }, { "name": "KIAA1841", "type": "synonym", "evidence": [ { "id": "NP_001186348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186348" } ] } ], "protein_names": [ { "name": "KIAA1841", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1841 homolog", "type": "synonym", "evidence": [ { "id": "NP_001186348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186348" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.196077.1, SRR13267654.163549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000059.1. On Sep 23, 2021 this sequence version replaced NP_001186348.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186348" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1841", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9", "locus": { "chromosome": "3", "start_pos": 2218575, "end_pos": 2193441, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019135", "url": "https://www.ensembl.org/id/ENSGALG00010019135" } ] } } ], "crossref": [ { "id": "A0A8V0ZAC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421196", "url": "https://www.ncbi.nlm.nih.gov/gene/421196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421196", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2X5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Y4", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAC9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGA2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20946", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20946", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20946:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20946:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186348", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGFSENNNFPYDNNQMVLDMILCSLIGVSQPINWDSVARLVPGYTSKECAKRFDELKSTGSSPVDNQYNPLMAAGENPVETLAVYIKSSLLDTRTEFQDPAIGQDSITITGRPSTTSTRNCSSESDKGSAHKGEESSDVNQGPNMVIHVCDEAKNLKEDFVCPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFDWLIRYVKRNTKDGEAYEIPALEPANVISILISSEFLKMDSLVEKCIHYCHKNMNAIVATPCNMNCINANLVAHIADLFTHNELEELKDKRDKFKSKLFCKKIERLFDLEYVNPDSRGNAATLYRCCLCKKLLTKETERRIPCVPGKINIDQHGNIVYVHIRDKTWEVHEYLIGLHEELKSWQDVYWRLWGTVNWLTCSKCNQSFLCTEFSHCQYHPQPVLYPGVASALGSTGTGVYPCCNQKVLRFDPTTLPKGCKVRDHMTSLPSRNEDGDSLPSQTTKILNDLLHHRDVIVVPFTKDENSDSGIGLCDEKGIECDMLVEPNTPWGPKTGEINAFLSLKNWTLQLKQQSLLSEEEEYTTGSEVTEDEVGDEEEVCRKPGRKEKLKKFYKHPKKGTSSPSIQKKEKPSEKPSSRDASPFTVSVQQNKWDASRSLRFNQDAQREDDQRRMSEITGHLLKIRLGDFGRIKSKDSKEYAGGIYSRLEAQVKASAQVNARQINTEKNARSKSRFGQGRPT", "length": 718, "header": "tr|A0A8V0ZAC9-1|A0A8V0ZAC9_CHICK Isoform 1 of KIAA1841 OS=Gallus gallus OX=9031 GN=KIAA1841 PE=4 SV=1 CANONICAL=A0A8V0ZAC9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9/entry#A0A8V0Z2X5-1", "sequence": { "sequence": "MSRGFSENNNFPYDNNQMVLDMILCSLIGVSQPINWDSVARLVPGYTSKECAKRFDELKSTGSSPVDNQYNPLMAAGENPVETLAVYIKSSLLDTRTEFQDPAIGQDSITITGRPSTTSTRNCSSESDKGSAHKGEESSDVNQGPNMVIHVCDEAKNLKEDFVCPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFDWLIRYVKRNTKDGEAYEIPALEPANVISILISSEFLKMDSLVEKCIHYCHKNMNAIVATPCNMNCINANLVAHIADLFTHNELEELKDKRDKFKSKLFCKKIERLFDLEYVNPDSRGNAATLYRDKTWEVHEYLIGLHEELKSWQDVYWRLWGTVNWLTCSKCNQSFLCTEFSHCQYHPQPVLYPGVASALGSTGTGVYPCCNQKVLRFDPTTLPKGCKVRDHMTSLPSRNEDGDSLPSQTTKILNDLLHHRDVIVVPFTKDENSDSGIGLCDEKGIECDMLVEPNTPWGPKTGEINAFLSLKNWTLQLKQQSLLSEEEEYTTGSEVTEDEVGDEEEVCRKPGRKEKLKKFYKHPKKGTSSPSIQKKEKPSEKPSSRDASPFTVSVQQNKWDASRSLRFNQDAQREDDQRRMSEITGHLLKIRLGDFGRIKSKDSKEYAGGIYSRLEAQVKASAQVNARQINTEKNARSKSRFGQGRPT", "length": 681, "header": "tr|A0A8V0Z2X5-1|A0A8V0Z2X5_CHICK Computationally mapped isoform of KIAA1841 OS=Gallus gallus OX=9031 GN=KIAA1841 PE=4 SV=1 CANONICAL=A0A8V0ZAC9-1" }, "locus": { "chromosome": "3", "start_pos": 2216653, "end_pos": 2197247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046307.1", "url": "https://www.ensembl.org/id/ENSGALT00010046307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027578.1", "url": "https://www.ensembl.org/id/ENSGALP00010027578.1" } ] } }, { "isoform_ac": "A0A8V0Z2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9/entry#A0A8V0Z2Y4-1", "sequence": { "sequence": "MSRGFSENNNFPYDNNQMVLDMILCSLIGVSQPINWDSVARLVPGYTSKECAKRFDELKSTGSSPVDNQYNPLMAAGENPVETLAVYIKSSLLDTRTEFQDPAIGQDSITITGRPSTTSTRNCSSESDKGSAHKGEESSDVNQGPNMVIHVCDEAKNLKEDFVCPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFDWLIRYVKRNTKDGEAYEIPALEPANVISILISSEFLKMDSLVEKCIHYCHKNMNAIVATPCNMNCINANLVAHIADLFTHNELEELKDKRDKFKSKLFCKKIERLFDLEYVNPDSRGNAATLYRCCLCKKLLTKETERRIPCVPGKINIDQHGNIVYVHIRDKTWEVHEYLIGLHEELKSWQDVYWRLWGTVNWLTCSKCNQSFLCTEFSHCQYHPQPVLYPGVASALGSTGTGVYPCCNQKVLRFDPTTLPKGCKVRDHMTSLPSRNEDGDSLPSQTTKILNDLLHHRDVIVVPFTKDENSDSGIGLCDEKGIECDMLVEPNTPWGPKTGEINAFLSLKNWTLQLKQQSLLSEEEEYTTGSEVTEDEVGDEEEVCRKPGRKEKLKKFYKHPKKGTSSPSIQKKEKPSEKPSSRDASPFTVSVQQNKWDASRSLRFNQDAQREDDQRRMSEITGHLLKIRLGDFGRIKSKDSKEVRLIIM", "length": 682, "header": "tr|A0A8V0Z2Y4-1|A0A8V0Z2Y4_CHICK Computationally mapped isoform of KIAA1841 OS=Gallus gallus OX=9031 GN=KIAA1841 PE=4 SV=1 CANONICAL=A0A8V0ZAC9-1" }, "locus": { "chromosome": "3", "start_pos": 2215630, "end_pos": 2197247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046322.1", "url": "https://www.ensembl.org/id/ENSGALT00010046322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027588.1", "url": "https://www.ensembl.org/id/ENSGALP00010027588.1" } ] } }, { "isoform_ac": "A0A8V0ZAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9/entry#A0A8V0ZAC9-1", "sequence": { "sequence": "MSRGFSENNNFPYDNNQMVLDMILCSLIGVSQPINWDSVARLVPGYTSKECAKRFDELKSTGSSPVDNQYNPLMAAGENPVETLAVYIKSSLLDTRTEFQDPAIGQDSITITGRPSTTSTRNCSSESDKGSAHKGEESSDVNQGPNMVIHVCDEAKNLKEDFVCPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFDWLIRYVKRNTKDGEAYEIPALEPANVISILISSEFLKMDSLVEKCIHYCHKNMNAIVATPCNMNCINANLVAHIADLFTHNELEELKDKRDKFKSKLFCKKIERLFDLEYVNPDSRGNAATLYRCCLCKKLLTKETERRIPCVPGKINIDQHGNIVYVHIRDKTWEVHEYLIGLHEELKSWQDVYWRLWGTVNWLTCSKCNQSFLCTEFSHCQYHPQPVLYPGVASALGSTGTGVYPCCNQKVLRFDPTTLPKGCKVRDHMTSLPSRNEDGDSLPSQTTKILNDLLHHRDVIVVPFTKDENSDSGIGLCDEKGIECDMLVEPNTPWGPKTGEINAFLSLKNWTLQLKQQSLLSEEEEYTTGSEVTEDEVGDEEEVCRKPGRKEKLKKFYKHPKKGTSSPSIQKKEKPSEKPSSRDASPFTVSVQQNKWDASRSLRFNQDAQREDDQRRMSEITGHLLKIRLGDFGRIKSKDSKEYAGGIYSRLEAQVKASAQVNARQINTEKNARSKSRFGQGRPT", "length": 718, "header": "tr|A0A8V0ZAC9-1|A0A8V0ZAC9_CHICK Isoform 1 of KIAA1841 OS=Gallus gallus OX=9031 GN=KIAA1841 PE=4 SV=1 CANONICAL=A0A8V0ZAC9-1" }, "locus": { "chromosome": "3", "start_pos": 2216653, "end_pos": 2197247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046342.1", "url": "https://www.ensembl.org/id/ENSGALT00010046342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027601.1", "url": "https://www.ensembl.org/id/ENSGALP00010027601.1" } ] } }, { "isoform_ac": "A0A8V0ZGA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9/entry#A0A8V0ZGA2-1", "sequence": { "sequence": "MSRGFSENNNFPYDNNQMVLDMILCSLIGVSQPINWDSVARLVPGYTSKECAKRFDELKSTGSSPVDNQYNPLMAAGENPVETLAVYIKSSLLDTRTEFQDPAIGQDSITITGRPSTTSTRNCSSESDKGSAHKGEESSDVNQGPNMVIHVCDEAKNLKEDFVCPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFDWLIRYVKRNTKDGEAYEIPALEPANVISILISSEFLKMDSLVEKCIHYCHKNMNAIVATPCNMNCINANLVAHIADLFTHNELEELKDKRDKFKRCCLCKKLLTKETERRIPCVPGKINIDQHGNIVYVHIRDKTWEVHEYLIGLHEELKSWQDVYWRLWGTVNWLTCSKCNQSFLCTEFSHCQYHPQPVLYPGVASALGSTGTGVYPCCNQKVLRFDPTTLPKGCKVRDHMTSLPSRNEDGDSLPSQTTKILNDLLHHRDVIVVPFTKDENSDSGIGLCDEKGIECDMLVEPNTPWGPKTGEINAFLSLKNWTLQLKQQSLLSEEEEYTTGSEVTEDEVGDEEEVCRKPGRKEKLKKFYKHPKKGTSSPSIQKKEKPSEKPSSRDASPFTVSVQQNKWDASRSLRFNQDAQREDDQRRMSEITGHLLKIRLGDFGRIKSKDSKEVRLIIM", "length": 653, "header": "tr|A0A8V0ZGA2-1|A0A8V0ZGA2_CHICK Computationally mapped isoform of KIAA1841 OS=Gallus gallus OX=9031 GN=KIAA1841 PE=4 SV=1 CANONICAL=A0A8V0ZAC9-1" }, "locus": { "chromosome": "3", "start_pos": 2215630, "end_pos": 2197247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046331.1", "url": "https://www.ensembl.org/id/ENSGALT00010046331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027594.1", "url": "https://www.ensembl.org/id/ENSGALP00010027594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421196", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "isotype switching", "id": "GO:0045190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAC9" }, { "id": "PF11822", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11822" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT and BTB", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 248, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 543, "end_pos": 545 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAE9-1", "uniprot_ac": "A0A8V0ZAE9", "uniprot_id": "A0A8V0ZAE9_CHICK", "mass": { "chemical_mass": 491347.0, "monoisotopic_mass": 491347.0 }, "refseq": { "ac": "XP_040507326", "name": "vacuolar protein sorting-associated protein 13D isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507326" }, "gene_names": [ { "name": "VPS13D", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ] }, { "name": "VPS13D", "type": "synonym", "evidence": [ { "id": "XP_040507326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507326" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting 13 homolog D", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 13D isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040507326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VPS13D", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9", "locus": { "chromosome": "21", "start_pos": 5355278, "end_pos": 5444061, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021092", "url": "https://www.ensembl.org/id/ENSGALG00010021092" } ] } } ], "crossref": [ { "id": "cd14306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419481", "url": "https://www.ncbi.nlm.nih.gov/gene/419481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IEFVMDQ", "url": "https://omabrowser.org/oma/group/IEFVMDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAD0", "url": "https://www.orthodb.org/?gene=A0A8V0ZAD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZNG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16166:SF141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166:SF141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040507326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKITLQIPFYRPHVDPWVISVSKLHLIGAPEKKEDFDEEREKLQERERKKALLVALEEKWKKERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDDITNPLQPFAFGICIKNVSMQNAVFEPVEKLMRKKQLNVADFSIYWDTDCTLLGDLPPAQLQEAMDKSMESHDHNYIMEPVCTSALLKRNCSKEPLRSRQTPRLECDIVLETIPLKLSQMQYQQIMAFLKELARKERQLKFRKWRPKVTVTENCREWWIFALNANLSEIREQRQRSTWEFVLHRAQDAVSYTDLYYCKLKGEPLSAAEQEEMHRIEDEQTYEELKILCELVHDKFHDLAESIKEPLPDSPGASPSAESAHGSSTGMLQYLQSWFPGWGGWYGYTQQPYEGEPFEGLLPDPQEQWNPEDILGADDFFDPAADASSMNTFTKRDHIFAKLNLQLQGGSFTLLHKEKKVARAEESAFMQLEFSGVKILAESLPRRNSSLLKVQLGGLFLRDLATEGTIFPVLVFPNPQKEVGCVSSFGLQNLSSEMTNQSTDPDAPVFEMLYERNPIHSNFERRLEVSTRPLNIIYNPQAIKKVADFFYKGRVHTSGFGYQSELEAKVAEAARRQYNKLKMQTKAEIRQTIDRLLVGDFIENSKSWTVCLDISAPQVIFPDDFKFVDPVLVVIDLGRILLTNSQEESKRNADAFSPEFNELSDEEYKTPLATPPNTPPPETSTNSGIKLSGFTGVEISEEQLQAHLMSKKMYERYTLSFLDLQIMVGRVKDNWKHVQDSDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGSLPDLKIHINEDKILALKNCCTQLSASETKSSDGLNLGKDKIFSEVDQLGTLHDSVMNLTQSVVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGTDFDLLMASHKNLSFDVPTGSLRDSRAQSPVYGPCDAHPIDASSLAERCAVASNTSSGNNGKDQESLIKLEYQFVSAECPSMNLDSSLQVISVQVNNLDIILNPETIVELIGFLQKSFPKEKEDSSPQPLMDDTERVWREQETFQSTYVQNTEVAVDIHWLNILLLRTVGMTNGEKYGRKIATASIGGTKVNVSMCSKFDVNGSLGCLHLMDLTQDGVKNQYVVSIGNTGRYENLIGDVDYFESLFFRLDDGSSLPDALSFTLTEKSKEECSLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAASKVTTVLATKTAEYSEMVSLFDTTPRSRDAANLEDNDGYAFGSPPLKSDTIKLILNINIESPIVSIPRKPGSPELLVGHLGQMSIQNFVPGEDESTSDRLQVEIKDIKMYSLNTSQFMSKKESASEVSQGLHSSGPASINSQEESQFTRHDFFESLHKGHAFHILNNTTIQFKLEKIPLGRDLDVTFPLSNEDFGISNIMKIEGKFVNPLQVVLAKHVYEQVLQTLDNLIYNEDLNKFPAAAASSTCHSSPSASALSTGTEFSSERKENGLFSHSSFNSIPSKSLTIRETKSFTQIQANFHISELQVQLSGDLTLGAQGLVSLKFQDFDVEFTKDHPQTLSIQIALRSLLMEDLLEKNPDSVYKNLMVSRGAPKPSSLAHKEYLSQSCPSVSNVEYPDMPRSLPSHMEEASNVFQLYQRPVCASRKKQKEDADSEYPLTPPPSPTADRSKLPCGKSHFDDSLVHINIFLVDRKHPEFSSRYNKINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKLQPEDTQQTSKSEVNTLSASAAQEPVNTKLDLKVHSLSLVLNKTMSELAKASVSKLAAHLEIIDGDLALQGSIGGLSLSDLTAHGEFYRERFTTSGEEALIFQVYKYGRPDPLLQRECDIRVTLRMASVQYVHTQRFQAEVVSFIQHFTQLQDVLGRQRAAIEGQTVRDKAQRASRVLLDIEAGAPVLLIPESSKSNSLIVANLGKLKVKNRFLFAGMPGTFSLKNKQDSAQFSSPLGTPKHSMKKTTSADESKVVMEGLFMKKPSGGNVSRLKSELNSLSKPQGQQSKLPVVPNPESPEDHICLLDCIVVDLQDMDIFAAERYPREYSKAVEDTSTDLSFPSYCVRQTGGSLLKEPFRLKLQVERNLDKELSHAVADILIHGNLSSVHCSLDLTKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTSMSFLVDMVNVSLELMDPKGKDECSSLARFDFKKSKLLFESSSNRTKSVNLVSHSMMAFDTRYAGQKSTAGMPNVFNCIFQSSKNTSSPGAIQIELHYRSTKDSSSFTVVLNNLRVFLIFDWLLLVHDFLYTPGDTKKRENVLSSRQRTYSSETSVVPKAVKSGVVTKRSSLHVSTEKQLEVKVNVTGTEFVVVEDMSCFDTNAIILKGTTVLTYKPKLLDRPFSGSLFGIEVFSCRLGNEQETALSIIDPVQIQVELVGNASYPSGSGLLDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPQQTSAAMPGSGASVAESSANPSSSLVAEPSCLTSENRETPKRVLDPVLEVQLARLQDLGFSMEDCRKALLCCQGDLKKAASWLFKNAEPLKSLSLSSSGRDSQGTVPFQFISGVEIKADSICICFIDDCMDCDVPLAELTFSRLNFLQHLRANPEGCARFTLSGDYYNRELSGWEPFIEPWPCSVSWQQHASSRLHPSRLKLEVKAKHRLDVNITSVFLEQYARTKQSWMEDYCKQDKEVNAVSSEEWTGSSEDSPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEMKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEENGTLLDDAHNVSEWKEVITGEEVPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEEVSPVSVDKVGTFFRYAAPDKNSSSSTLGSPISRTNIIHPQVYFSSLPPVRVVFEVTMEGSARKVITVRSALIVKNKLETPMELRLDSPSAPDKPVVLPAVMPGDAFAIPLHLTSWRLQARPKGLGVFFCKAPIHWTDVQKTAEVCSSKRECHSMDSENSRFFRFCVAIKKENYPDYMPSSIFSDSAKQIFRQPGHTIYLLPTVVVCNLLPCELEFYVKGTPISGTLKPGKEVALHTADTSQNIELGVKLENFAICKELLIPPGTQNYMVRMRLYDVNKRQLNLTIRIVCRAEGSLKILISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNFCTMRVGKGIHPEGMPGWCQGFSLDGGSGVRALKVIQHGNRPGLIYNIGINVKKGRGRYIDTCMVTFAPRYLLDNKSSYKLAFVQREFARGQETSNPDGYISTLPGSSVVFHWPRNDYDQLLCVRLMDFPNCIWSGGFEVNKNNSFHINMRDTLGKCYFLRVEITLQGATYHVAFSDTDQLPPPFRIDNFSKVPIVFNQHGVVEPRLYTEVKPMTSLDYAWDEPILPSFVLVTVKGAGSSEIVCSMNDFQDSKQLYYENFIYIAATYTFSGLQETSVRPVASNRDAAYAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLCHEGSSVPHNPHKPSPRSVESCMILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFRDGKLTCGIHGLVVQAKGGILGLHDGAEVVLGPDTSLELLGSVPPEQQFINQKMRPGSGVLAVRVIPDGPTRVLQITDFNQRRNDRLSGGGDELPITEQDLRKLKNPNMEQELEVLVKLEGGIGLSLVNKVPEELIFASLTRINVHYTHMSASQVLELSVQDVQVDNQLIGTTRPFMLFLTPRMSENEPVETAPAVQVNAMKFPSKNALTDIYKHLMITARKFTVQIEEKLLLKLLSFFGYAQSESEVERYDENLHEKVVEKGGGQKRYYFENLKISVPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETQEFIINDVLKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQTEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4389, "header": "tr|A0A8V0ZAE9-1|A0A8V0ZAE9_CHICK Isoform 1 of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=1 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#A0A8V0ZAD0-1", "sequence": { "sequence": "MIKRRGCQRLEGKHILEVCMCFKPGMGLLKVKGNKETGLQRKHLQKAKLRRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 218, "header": "tr|A0A8V0ZAD0-1|A0A8V0ZAE9_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=1 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "locus": { "chromosome": "21", "start_pos": 5362901, "end_pos": 5356594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051049.1", "url": "https://www.ensembl.org/id/ENSGALT00010051049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030240.1", "url": "https://www.ensembl.org/id/ENSGALP00010030240.1" } ] } }, { "isoform_ac": "A0A8V0ZAE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#A0A8V0ZAE9-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKITLQIPFYRPHVDPWVISVSKLHLIGAPEKKEDFDEEREKLQERERKKALLVALEEKWKKERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDDITNPLQPFAFGICIKNVSMQNAVFEPVEKLMRKKQLNVADFSIYWDTDCTLLGDLPPAQLQEAMDKSMESHDHNYIMEPVCTSALLKRNCSKEPLRSRQTPRLECDIVLETIPLKLSQMQYQQIMAFLKELARKERQLKFRKWRPKVTVTENCREWWIFALNANLSEIREQRQRSTWEFVLHRAQDAVSYTDLYYCKLKGEPLSAAEQEEMHRIEDEQTYEELKILCELVHDKFHDLAESIKEPLPDSPGASPSAESAHGSSTGMLQYLQSWFPGWGGWYGYTQQPYEGEPFEGLLPDPQEQWNPEDILGADDFFDPAADASSMNTFTKRDHIFAKLNLQLQGGSFTLLHKEKKVARAEESAFMQLEFSGVKILAESLPRRNSSLLKVQLGGLFLRDLATEGTIFPVLVFPNPQKEVGCVSSFGLQNLSSEMTNQSTDPDAPVFEMLYERNPIHSNFERRLEVSTRPLNIIYNPQAIKKVADFFYKGRVHTSGFGYQSELEAKVAEAARRQYNKLKMQTKAEIRQTIDRLLVGDFIENSKSWTVCLDISAPQVIFPDDFKFVDPVLVVIDLGRILLTNSQEESKRNADAFSPEFNELSDEEYKTPLATPPNTPPPETSTNSGIKLSGFTGVEISEEQLQAHLMSKKMYERYTLSFLDLQIMVGRVKDNWKHVQDSDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGSLPDLKIHINEDKILALKNCCTQLSASETKSSDGLNLGKDKIFSEVDQLGTLHDSVMNLTQSVVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGTDFDLLMASHKNLSFDVPTGSLRDSRAQSPVYGPCDAHPIDASSLAERCAVASNTSSGNNGKDQESLIKLEYQFVSAECPSMNLDSSLQVISVQVNNLDIILNPETIVELIGFLQKSFPKEKEDSSPQPLMDDTERVWREQETFQSTYVQNTEVAVDIHWLNILLLRTVGMTNGEKYGRKIATASIGGTKVNVSMCSKFDVNGSLGCLHLMDLTQDGVKNQYVVSIGNTGRYENLIGDVDYFESLFFRLDDGSSLPDALSFTLTEKSKEECSLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAASKVTTVLATKTAEYSEMVSLFDTTPRSRDAANLEDNDGYAFGSPPLKSDTIKLILNINIESPIVSIPRKPGSPELLVGHLGQMSIQNFVPGEDESTSDRLQVEIKDIKMYSLNTSQFMSKKESASEVSQGLHSSGPASINSQEESQFTRHDFFESLHKGHAFHILNNTTIQFKLEKIPLGRDLDVTFPLSNEDFGISNIMKIEGKFVNPLQVVLAKHVYEQVLQTLDNLIYNEDLNKFPAAAASSTCHSSPSASALSTGTEFSSERKENGLFSHSSFNSIPSKSLTIRETKSFTQIQANFHISELQVQLSGDLTLGAQGLVSLKFQDFDVEFTKDHPQTLSIQIALRSLLMEDLLEKNPDSVYKNLMVSRGAPKPSSLAHKEYLSQSCPSVSNVEYPDMPRSLPSHMEEASNVFQLYQRPVCASRKKQKEDADSEYPLTPPPSPTADRSKLPCGKSHFDDSLVHINIFLVDRKHPEFSSRYNKINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKLQPEDTQQTSKSEVNTLSASAAQEPVNTKLDLKVHSLSLVLNKTMSELAKASVSKLAAHLEIIDGDLALQGSIGGLSLSDLTAHGEFYRERFTTSGEEALIFQVYKYGRPDPLLQRECDIRVTLRMASVQYVHTQRFQAEVVSFIQHFTQLQDVLGRQRAAIEGQTVRDKAQRASRVLLDIEAGAPVLLIPESSKSNSLIVANLGKLKVKNRFLFAGMPGTFSLKNKQDSAQFSSPLGTPKHSMKKTTSADESKVVMEGLFMKKPSGGNVSRLKSELNSLSKPQGQQSKLPVVPNPESPEDHICLLDCIVVDLQDMDIFAAERYPREYSKAVEDTSTDLSFPSYCVRQTGGSLLKEPFRLKLQVERNLDKELSHAVADILIHGNLSSVHCSLDLTKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTSMSFLVDMVNVSLELMDPKGKDECSSLARFDFKKSKLLFESSSNRTKSVNLVSHSMMAFDTRYAGQKSTAGMPNVFNCIFQSSKNTSSPGAIQIELHYRSTKDSSSFTVVLNNLRVFLIFDWLLLVHDFLYTPGDTKKRENVLSSRQRTYSSETSVVPKAVKSGVVTKRSSLHVSTEKQLEVKVNVTGTEFVVVEDMSCFDTNAIILKGTTVLTYKPKLLDRPFSGSLFGIEVFSCRLGNEQETALSIIDPVQIQVELVGNASYPSGSGLLDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPQQTSAAMPGSGASVAESSANPSSSLVAEPSCLTSENRETPKRVLDPVLEVQLARLQDLGFSMEDCRKALLCCQGDLKKAASWLFKNAEPLKSLSLSSSGRDSQGTVPFQFISGVEIKADSICICFIDDCMDCDVPLAELTFSRLNFLQHLRANPEGCARFTLSGDYYNRELSGWEPFIEPWPCSVSWQQHASSRLHPSRLKLEVKAKHRLDVNITSVFLEQYARTKQSWMEDYCKQDKEVNAVSSEEWTGSSEDSPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEMKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEENGTLLDDAHNVSEWKEVITGEEVPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEEVSPVSVDKVGTFFRYAAPDKNSSSSTLGSPISRTNIIHPQVYFSSLPPVRVVFEVTMEGSARKVITVRSALIVKNKLETPMELRLDSPSAPDKPVVLPAVMPGDAFAIPLHLTSWRLQARPKGLGVFFCKAPIHWTDVQKTAEVCSSKRECHSMDSENSRFFRFCVAIKKENYPDYMPSSIFSDSAKQIFRQPGHTIYLLPTVVVCNLLPCELEFYVKGTPISGTLKPGKEVALHTADTSQNIELGVKLENFAICKELLIPPGTQNYMVRMRLYDVNKRQLNLTIRIVCRAEGSLKILISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNFCTMRVGKGIHPEGMPGWCQGFSLDGGSGVRALKVIQHGNRPGLIYNIGINVKKGRGRYIDTCMVTFAPRYLLDNKSSYKLAFVQREFARGQETSNPDGYISTLPGSSVVFHWPRNDYDQLLCVRLMDFPNCIWSGGFEVNKNNSFHINMRDTLGKCYFLRVEITLQGATYHVAFSDTDQLPPPFRIDNFSKVPIVFNQHGVVEPRLYTEVKPMTSLDYAWDEPILPSFVLVTVKGAGSSEIVCSMNDFQDSKQLYYENFIYIAATYTFSGLQETSVRPVASNRDAAYAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLCHEGSSVPHNPHKPSPRSVESCMILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFRDGKLTCGIHGLVVQAKGGILGLHDGAEVVLGPDTSLELLGSVPPEQQFINQKMRPGSGVLAVRVIPDGPTRVLQITDFNQRRNDRLSGGGDELPITEQDLRKLKNPNMEQELEVLVKLEGGIGLSLVNKVPEELIFASLTRINVHYTHMSASQVLELSVQDVQVDNQLIGTTRPFMLFLTPRMSENEPVETAPAVQVNAMKFPSKNALTDIYKHLMITARKFTVQIEEKLLLKLLSFFGYAQSESEVERYDENLHEKVVEKGGGQKRYYFENLKISVPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETQEFIINDVLKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQTEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4389, "header": "tr|A0A8V0ZAE9-1|A0A8V0ZAE9_CHICK Isoform 1 of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=1 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "locus": { "chromosome": "21", "start_pos": 5441598, "end_pos": 5356594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051064.1", "url": "https://www.ensembl.org/id/ENSGALT00010051064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030255.1", "url": "https://www.ensembl.org/id/ENSGALP00010030255.1" } ] } }, { "isoform_ac": "A0A8V0ZHH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#A0A8V0ZHH0-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKITLQIPFYRPHVDPWVISVSKLHLIGAPEKKEDFDEEREKLQERERKKALLVALEEKWKKERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDDITNPLQPFAFGICIKNVSMQNAVFEPVEKLMRKKQLNVADFSIYWDTDCTLLGDLPPAQLQEAMDKSMESHDHNYIMEPVCTSALLKRNCSKEPLRSRQTPRLECDIVLETIPLKLSQMQYQQIMAFLKELARKERQLKFRKWRPKVTVTENCREWWIFALNANLSEIREQRQRSTWEFVLHRAQDAVSYTDLYYCKLKGEPLSAAEQEEMHRIEDEQTYEELKILCELVHDKFHDLAESIKEPLPDSPGASPSAESAHGSSTGMLQYLQSWFPGWGGWYGYTQQPYEGEPFEGLLPDPQEQWNPEDILGADDFFDPAADASSMNTFTKRDHIFAKLNLQLQGGSFTLLHKEKKVARAEESAFMQLEFSGVKILAESLPRRNSSLLKVQLGGLFLRDLATEGTIFPVLVFPNPQKEVGCVSSFGLQNLSSEMTNQSTDPDAPVFEMLYERNPIHSNFERRLEVSTRPLNIIYNPQAIKKVADFFYKGRVHTSGFGYQSELEAKVAEAARRQYNKLKMQTKAEIRQTIDRLLVGDFIENSKSWTVCLDISAPQVIFPDDFKFVDPVLVVIDLGRILLTNSQEESKRNADAFSPEFNELSDEEYKTPLATPPNTPPPETSTNSGIKLSGFTGVEISEEQLQAHLMSKKMYERYTLSFLDLQIMVGRVKDNWKHVQDSDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGSLPDLKIHINEDKILALKNCCTQLSASETKSSDGLNLGKDKIFSEVDQLGTLHDSVMNLTQSVVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGTDFDLLMASHKNLSFDVPTGSLRDSRAQSPVYGPCDAHPIDASSLAERCAVASNTSSGNNGKDQESLIKLEYQFVSAECPSMNLDSSLQVISVQVNNLDIILNPETIVELIGFLQKSFPKEKEDSSPQPLMDDTERVWREQETFQSTYVQNTEVAVDIHWLNILLLRTVGMTNGEKYGRKIATASIGGTKVNVSMCSKFDVNGSLGCLHLMDLTQDGVKNQYVVSIGNTGRYENLIGDVDYFESLFFRLDDGSSLPDALSFTLTEKSKEECSLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAASKVTTVLATKTAEYSEMVSLFDTTPRSRDAANLEDNDGYAFGSPPLKSDTIKLILNINIESPIVSIPRKPGSPELLVGHLGQMSIQNFVPGEDESTSDRLQVEIKDIKMYSLNTSQFMSKKESASEVSQGLHSSGPASINSQEESQFTRHDFFESLHKGHAFHILNNTTIQFKLEKIPLGRDLDVTFPLSNEDFGISNIMKIEGKFVNPLQVVLAKHVYEQVLQTLDNLIYNEDLNKFPAAAASSTCHSSPSASALSTGTEFSSERKENGLFSHSSFNSIPSKSLTIRETKSFTQIQANFHISELQVQLSGDLTLGAQGLVSLKFQDFDVEFTKDHPQTLSIQIALRSLLMEDLLEKNPDSVYKNLMVSRGAPKPSSLAHKEYLSQSCPSVSNVEYPDMPRSLPSHMEEASNVFQLYQRPVCASRKKQKEDADSEYPLTPPPSPTADRSKLPCGKSHFDDSLVHINIFLVDRKHPEFSSRYNKINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKLQPEDTQQTSKSEVNTLSASAAQEPVNTKLDLKVHSLSLVLNKTMSELAKASVSKLAAHLEIIDGDLALQGSIGGLSLSDLTAHGEFYRERFTTSGEEALIFQVYKYGRPDPLLQRECDIRVTLRMASVQYVHTQRFQAEVVSFIQHFTQLQDVLGRQRAAIEGQTVRDKAQRASRVLLDIEAGAPVLLIPESSKSNSLIVANLGKLKVKNRFLFAGMPGTFSLKNKDLILQGNAYKDPVLFEQDSAQFSSPLGTPKHSMKKTTSADESKVVMEGLFMKKPSGGNVSRLKSELNSLSKPQGQQSKLPVVPNPESPEDHICLLDCIVVDLQDMDIFAAERYPREYSKAVEDTSTDLSFPSYCVRQTGGSLLKEPFRLKLQVERNLDKELSHAVADILIHGNLSSVHCSLDLTKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTSMSFLVDMVNVSLELMDPKGKDECSSLARFDFKKSKLLFESSSNRTKSVNLVSHSMMAFDTRYAGQKSTAGMPNVFNCIFQSSKNTSSPGAIQIELHYRSTKDSSSFTVVLNNLRVFLIFDWLLLVHDFLYTPGDTKKRENVLSSRQRTYSSETSVVPKAVKSGVVTKRSSLHVSTEKQLEVKVNVTGTEFVVVEDMSCFDTNAIILKGTTVLTYKPKLLDRPFSGSLFGIEVFSCRLGNEQETALSIIDPVQIQVELVGNASYPSGSGLLDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPQQTSAAMPGSGASVAESSANPSSSLVAEPSCLTSENRETPKRVLDPVLEVQLARLQDLGFSMEDCRKALLCCQGDLKKAASWLFKNAEPLKSLSLSSSGRDSQGTVPFQFISGVEIKADSICICFIDDCMDCDVPLAELTFSRLNFLQHLRANPEGCARFTLSGDYYNRELSGWEPFIEPWPCSVSWQQHASSRLHPSRLKLEVKAKHRLDVNITSVFLEQYARTKQSWMEDYCKQDKEVNAVSSEEWTGSSEDSPCFGQTEMKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEENGTLLDDAHNVSEWKEVITGEEVPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEEVSPVSVDKVGTFFRYAAPDKNSSSSTLGSPISRTNIIHPQVYFSSLPPVRVVFEVTMEGSARKVITVRSALIVKNKLETPMELRLDSPSAPDKPVVLPAVMPGDAFAIPLHLTSWRLQARPKGLGVFFCKAPIHWTDVQKTAEVCSSKRECHSMDSENSRFFRFCVAIKKENYPDYMPSSIFSDSAKQIFRQPGHTIYLLPTVVVCNLLPCELEFYVKGTPISGTLKPGKEVALHTADTSQNIELGVKLENFAICKELLIPPGTQNYMVRMRLYDVNKRQLNLTIRIVCRAEGSLKILISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNFCTMRVGKGIHPEGMPGWCQGFSLDGGSGVRALKVIQHGNRPGLIYNIGINVKKGRGRYIDTCMVTFAPRYLLDNKSSYKLAFVQREFARGQETSNPDGYISTLPGSSVVFHWPRNDYDQLLCVRLMDFPNCIWSGGFEVNKNNSFHINMRDTLGKCYFLRVEITLQGATYHVAFSDTDQLPPPFRIDNFSKVPIVFNQHGVVEPRLYTEVKPMTSLDYAWDEPILPSFVLVTVKGAGSSEIVCSMNDFQDSKQLYYENFIYIAATYTFSGLQETSVRPVASNRDAAYAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLCHEGSSVPHNPHKPSPRSVESCMILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFRDGKLTCGIHGLVVQAKGGILGLHDGAEVVLGPDTSLELLGSVPPEQQFINQKMRPGSGVLAVRVIPDGPTRVLQITDFNQRRNDRLSGGGDELPITEQDLRKLKNPNMEQELEVLVKLEGGIGLSLVNKVPEELIFASLTRINVHYTHMSASQVLELSVQDVQVDNQLIGTTRPFMLFLTPRMSENEPVETAPAVQVNAMKFPSKNALTDIYKHLMITARKFTVQIEEKLLLKLLSFFGYAQSESEVERYDENLHEKVVEKGGGQKRYYFENLKISVPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETQEFIINDVLKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQTEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4380, "header": "tr|A0A8V0ZHH0-1|A0A8V0ZHH0_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=1 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "locus": { "chromosome": "21", "start_pos": 5441598, "end_pos": 5356594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051057.1", "url": "https://www.ensembl.org/id/ENSGALT00010051057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030248.1", "url": "https://www.ensembl.org/id/ENSGALP00010030248.1" } ] } }, { "isoform_ac": "A0A8V0ZHH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#A0A8V0ZHH7-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKITLQIPFYRPHVDPWVISVSKLHLIGAPEKKEDFDEEREKLQERERKKALLVALEEKWKKERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDDITNPLQPFAFGICIKNVSMQNAVFEPVEKLMRKKQLNVADFSIYWDTDCTLLGDLPPAQLQEAMDKSMESHDHNYIMEPVCTSALLKRNCSKEPLRSRQTPRLECDIVLETIPLKLSQMQYQQIMAFLKELARKERQLKFRKWRPKVTVTENCREWWIFALNANLSEIREQRQRSTWEFVLHRAQDAVSYTDLYYCKLKGEPLSAAEQEEMHRIEDEQTYEELKILCELVHDKFHDLAESIKEPLPDSPGASPSAESAHGSSTGMLQYLQSWFPGWGGWYGYTQQPYEGEPFEGLLPDPQEQWNPEDILGADDFFDPAADASSMNTFTKRDHIFAKLNLQLQGGSFTLLHKEKKVARAEESAFMQLEFSGVKILAESLPRRNSSLLKVQLGGLFLRDLATEGTIFPVLVFPNPQKEVGCVSSFGLQNLSSEMTNQSTDPDAPVFEMLYERNPIHSNFERRLEVSTRPLNIIYNPQAIKKVADFFYKGRVHTSGFGYQSELEAKVAEAARRQYNKLKMQTKAEIRQTIDRLLVGDFIENSKSWTVCLDISAPQVIFPDDFKFVDPVLVVIDLGRILLTNSQEESKRNADAFSPEFNELSDEEYKTPLATPPNTPPPETSTNSGIKLSGFTGVEISEEQLQAHLMSKKMYERYTLSFLDLQIMVGRVKDNWKHVQDSDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGSLPDLKIHINEDKILALKNCCTQLSASETKSSDGLNLGKDKIFSEVDQLGTLHDSVMNLTQSVVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGTDFDLLMASHKNLSFDVPTGSLRDSRAQSPVYGPCDAHPIDASSLAERCAVASNTSSGNNGKDQESLIKLEYQFVSAECPSMNLDSSLQVISVQVNNLDIILNPETIVELIGFLQKSFPKEKEDSSPQPLMDDTERVWREQETFQSTYVQNTEVAVDIHWLNILLLRTVGMTNGEKYGRKIATASIGGTKVNVSMCSKFDVNGSLGCLHLMDLTQDGVKNQYVVSIGNTGRYENLIGDVDYFESLFFRLDDGSSLPDALSFTLTEKSKEECSLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAASKVTTVLATKTAEYSEMVSLFDTTPRSRDAANLEDNDGYAFGSPPLKSDTIKLILNINIESPIVSIPRKPGSPELLVGHLGQMSIQNFVPGEDESTSDRLQVEIKDIKMYSLNTSQFMSKKESASEVSQGLHSSGPASINSQEESQFTRHDFFESLHKGHAFHILNNTTIQFKLEKIPLGRDLDVTFPLSNEDFGISNIMKIEGKFVNPLQVVLAKHVYEQVLQTLDNLIYNEDLNKFPAAAASSTCHSSPSASALSTGTEFSSERKENGLFSHSSFNSIPSKSLTIRETKSFTQIQANFHISELQVQLSGDLTLGAQGLVSLKFQDFDVEFTKDHPQTLSIQIALRSLLMEDLLEKNPDSVYKNLMVSRGAPKPSSLAHKEYLSQSCPSVSNVEYPDMPRSLPSHMEEASNVFQLYQRPVCASRKKQKEDADSEYPLTPPPSPTADRSKLPCGKSHFDDSLVHINIFLVDRKHPEFSSRYNKINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKLQPEDTQQTSKSEVNTLSASAAQEPVNTKLDLKVHSLSLVLNKTMSELAKASVSKLAAHLEIIDGDLALQGSIGGLSLSDLTAHGEFYRERFTTSGEEALIFQVYKYGRPDPLLQRECDIRVTLRMASVQYVHTQRFQAEVVSFIQHFTQLQDVLGRQRAAIEGQTVRDKAQRASRVLLDIEAGAPVLLIPESSKSNSLIVANLGKLKVKNRFLFAGMPGTFSLKNKQDSAQFSSPLGTPKHSMKKTTSADESKVVMEGLFMKKPSGGNVSRLKSELNSLSKPQGQQSKLPVVPNPESPEDHICLLDCIVVDLQDMDIFAAERYPREYSKAVEDTSTDLSFPSYCVRQTGGSLLKEPFRLKLQVERNLDKELSHAVADILIHGNLSSVHCSLDLTKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTSMSFLVDMVNVSLELMDPKGKDECSSLARFDFKKSKLLFESSSNRTKSVNLVSHSMMAFDTRYAGQKSTAGMPNVFNCIFQSSKNTSSPGAIQIELHYRSTKDSSSFTVVLNNLRVFLIFDWLLLVHDFLYTPGDTKKRENVLSSRQRTYSSETSVVPKAVKSGVVTKRSSLHVSTEKQLEVKVNVTGTEFVVVEDMSCFDTNAIILKGTTVLTYKPKLLDRPFSGSLFGIEVFSCRLGNEQETALSIIDPVQIQVELVGNASYPSGSGLLDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPQQTSAAMPGSGASVAESSANPSSSLVAEPSCLTSENRETPKRVLDPVLEVQLARLQDLGFSMEDCRKALLCCQGDLKKAASWLFKNAEPLKSLSLSSSGRDSQGTVPFQFISGVEIKADSICICFIDDCMDCDVPLAELTFSRLNFLQHLRANPEGCARFTLSGDYYNRELSGWEPFIEPWPCSVSWQQHASSRLHPSRLKLEVKAKHRLDVNITSVFLEQYARTKQSWMEDYCKQDKEVNAVSSEEWTGSSEDSPCFGQTEMKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEENGTLLDDAHNVSEWKEVITGEEVPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEEVSPVSVDKVGTFFRYAAPDKNSSSSTLGSPISRTNIIHPQVYFSSLPPVRVVFEVTMEGSARKVITVRSALIVKNKLETPMELRLDSPSAPDKPVVLPAVMPGDAFAIPLHLTSWRLQARPKGLGVFFCKAPIHWTDVQKTAEVCSSKRECHSMDSENSRFFRFCVAIKKENYPDYMPSSIFSDSAKQIFRQPGHTIYLLPTVVVCNLLPCELEFYVKGTPISGTLKPGKEVALHTADTSQNIELGVKLENFAICKELLIPPGTQNYMVRMRLYDVNKRQLNLTIRIVCRAEGSLKILISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNFCTMRVGKGIHPEGMPGWCQGFSLDGGSGVRALKVIQHGNRPGLIYNIGINVKKGRGRYIDTCMVTFAPRYLLDNKSSYKLAFVQREFARGQETSNPDGYISTLPGSSVVFHWPRNDYDQLLCVRLMDFPNCIWSGGFEVNKNNSFHINMRDTLGKCYFLRVEITLQGATYHVAFSDTDQLPPPFRIDNFSKVPIVFNQHGVVEPRLYTEVKPMTSLDYAWDEPILPSFVLVTVKGAGSSEIVCSMNDFQDSKQLYYENFIYIAATYTFSGLQETSVRPVASNRDAAYAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLCHEGSSVPHNPHKPSPRSVESCMILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFRDGKLTCGIHGLVVQAKGGILGLHDGAEVVLGPDTSLELLGSVPPEQQFINQKMRPGSGVLAVRVIPDGPTRVLQITDFNQRRNDRLSGGGDELPITEQDLRKLKNPNMEQELEVLVKLEGGIGLSLVNKVPEELIFASLTRINVHYTHMSASQVLELSVQDVQVDNQLIGTTRPFMLFLTPRMSENEPVETAPAVQVNAMKFPSKNALTDIYKHLMITARKFTVQIEEKLLLKLLSFFGYAQSESEVERYDENLHEKVVEKGGGQKRYYFENLKISVPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETQEFIINDVLKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQTEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRCSASVKTWGSCSSLGQADIYSRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4386, "header": "tr|A0A8V0ZHH7-1|A0A8V0ZHH7_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=1 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "locus": { "chromosome": "21", "start_pos": 5441598, "end_pos": 5356594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051062.1", "url": "https://www.ensembl.org/id/ENSGALT00010051062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030253.1", "url": "https://www.ensembl.org/id/ENSGALP00010030253.1" } ] } }, { "isoform_ac": "A0A8V0ZNG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9/entry#A0A8V0ZNG6-1", "sequence": { "sequence": "RKAEFAVKVGENSSDSHRCSASVKTWGSCSSLGQADIYSRTQAERVRKPRCCRGPQGLLPRYSAREAEGQEQLFKLTDNIQDEFFIAVENIEKYCVLISSKAVYFLKSGDYPDREAIFLEVKYDDLYHCLVSKDHGKVYVQLTKKAVNTSSGVAMPGPSQQKPMVNVKSEVLAVKLCQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 207, "header": "tr|A0A8V0ZNG6-1|A0A8V0ZNG6_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Gallus gallus OX=9031 GN=VPS13D PE=4 SV=1 CANONICAL=A0A8V0ZAE9-1" }, "locus": { "chromosome": "21", "start_pos": 5373571, "end_pos": 5356594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051050.1", "url": "https://www.ensembl.org/id/ENSGALT00010051050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030241.1", "url": "https://www.ensembl.org/id/ENSGALP00010030241.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1761, "start_aa": "Thr", "end_pos": 1761, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1761", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1767, "start_aa": "Thr", "end_pos": 1767, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1767", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHP9-1", "protein_name": "Vacuolar protein sorting 13 homolog D", "gene_name": "Vps13d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGAPEKIQDFNDEKEKLLERERKKVLLQALEERWKSERRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGLTNPSHPFAFGICIKNVSMQNAANEPVQKLMRKKRLDVAEFSIYWDVNCTLLGDLPQAELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQVKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCCTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREPQFDSPGASPGDPDGSGGSGMLQYLQSWFPGWGGWYGQQSPEGKVAEGLTAESHEHWMPEDILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHQERGAAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDDSASEENQFSDDEYKTPLATPPSTPPPETNSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSDTQFREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAFQTDVATLNDQSATTSVSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIMEQGTVQSTYEQNTEVAVEIHRLNLLLLRTVGMSDGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSIGYENIVSDIGYFESVFVRMEDASLTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPKKTRDPFVLEENEIYGFGLPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGRDGAGPEVSRAFCPPSGSASVSSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERETELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPPSPCPNSPLPPLSSCGEPTAEKKENGLFSHSSFSSASQKSLSVKESKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSCVEYPAMPRSLPSHMEEAPNVFQLYQRPISTCRKKQKEVQDKSYPQTPPPSPSVDEPKVLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEGPLQNVKAEATASMQSELQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLVAHMEMIEGDLALQGSIGSLSLSDLTPHGDLYRERFTTSGEEALIFQTFKYGQPDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAVEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPTDTMKHSMKKMPSTEDPKGPQVQGLFMMPPAGMGLGSLKSDFVPSASIKQRGQQAVPPISQSSSSPEDHVCLLDCIVVDLQDMDIFAAERHPREGSKASESSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQKPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDVKKQNVTPARYRNASSESAVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSAALEADSVSSNLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSSRDNQGAMSAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKRRLDINITSVLIDQYVSTKESWLADYCKEDKETESAKTEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDISRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPSGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPIVFTQHGVAEPRLRTEVKPMMSLHYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWCFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDSSVELLGSVPPEQQFANQKMRPGSGMLSVRVIPDGPTRALQITDFCQRKSERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGIGVSLINKVPEELVFASLTGINIHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQKFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAEQGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYIDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSEDQEQLELDS", "length": 4390 }, "evidence": [ { "id": "A0A8V0ZAE9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1ART1-1", "protein_name": "Vacuolar protein sorting 13D", "gene_name": "Vps13d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISGLHVIGGPEKIQDFNDEKEKLLERERKKALLQALEERWKKGEPYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSRPFAFGICIKNVSMQNAANEPVQKLMRKKRLDVAEFSIYWDVNCTLLGDLPQAELQEAMARSMESRSHHYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQLKFRKWKPKVAVSKNCREWWYFALNANLYEIREQRKCWTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMCRIEEEQSFEELKILRELVHDRFYKQEELAESLREPQFDSPGTSPGDPDGSGGSGMLQYLQSWFPGWGGWYGQQSPEGKVVEGLTAESHEHWTPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNVQLQRGTVTLLHKEQGTAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYDKLKVQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRMLLTNTQEDSRRKSGDGSASEENQFSDDEYKTPLATPPSTPPPETSSSNGEKTPPFSGVEFSEEQLQAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPETKPSDTQIREKIFPQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAFQTDVTTLNDQSATSVSLEKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDVSPQPLMTDLERSIVEQGTIQSTYEQNTEVAVEIHRLNLLLLRTVGMADGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQENVKSQYVVSIGNSVGYENIVSDIGYFESVFVRMEDAALTEALSFTFAEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPKKTREPFVLEENEIYGFGLPSPRSDTVKLILNINIESPVVSIPRRPGSPELLVGHLGQIFIQNFVAGDDDSRSDRLQVEIKDIKLYSLNCTQLAGRDNAGPEVNRTFCPPSGLASVNSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFAASAPTSPCPNSPLPQLSSCGEPCVEKKENGLFSHSSFSSTSQKSLSVKEAKAFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMVSRGAPKPSSLAQKEYLSQSCPSVSSVEYPDMPRSLPSHMEEAPNVFQLYQRPISTCRKKPKEAQDKSYPQTPPPSPSVDEPNMLVGKSKFDDSLVHINIFLVDKKHPEFSSSYGRINRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEGLLQNVKAESSASMESEHQEPVNSKLDLKVHSLSLVLSKATSELAKANVSKLMAHMEMIEGDLALQGSIGSLSLSDLTPHGDFYRERFTTSGEEALIFQTFKYGQPDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDILGRQRAAIEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPAGTPKHSMRKMTTTEDPKGPQVQGLFMMPPAGVGLGSLKSDFVPSASIKQRGQQAVPPVSQSSSSPEDHVCLLDCIVVDLQDMDIFAAERHPREGSKASEHSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNLGEPIEDFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEGTGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYSGQKPSHGMTNVFNCIFQPSKSSSATQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNVTPARHRNASSESAVVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEQDTALSIVDPVQIQVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQASAAAPDSSALEVDSISCSLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLVCQGQLKKAASWLFKNAEPLKSLSLVSSSSRDNPGTMPAPRISGVEVKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHIRTNPEGFAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQASSRLHPPRLKLEAKAKRRLDINITSVLIDQYISTKESWLADYCKEDKETESAKTEDWMGSSVDPPCFGQTEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGMGVFFCKVPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALPTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDVNRRQLNLTIRIACRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPNGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMMSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFSGLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNPNKPSATRSIEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFHEGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDSSMELLGPVPPEQQFANQKMRPGSGMLSIRVIPDGPTRALQITDFCQRKSERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGVGVSLINKVPEELVFASLTGINIHYTQLAASHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENIHEKTAEQGGTPTRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAANSSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4359 }, "evidence": [ { "id": "A0A8V0ZAE9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5THJ4-1", "protein_name": "Intermembrane lipid transfer protein VPS13D", "gene_name": "VPS13D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLAGREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQATFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFSLQDKESVPSASPTGIPKHSLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKSEFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLLDCVVVDLQDMDIFAAERHPREYSKAPEDSSGDLIFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKLLYESFSNQTKSINLVSHSMMAFDTRYAGQKTSPGMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKSGVVTKRSSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIQMELVGNSSYQNSSGLMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDSVALESDSVGTYLPGASRVGEEIREGTRHTLDPVLELQLARLQELGFSMDDCRKALLACQGQLKKAASWLFKNAEPLKSLSLASTSRDSPGAVAAPLISGVEIKAESVCICFIDDCMDCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVSTKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQLYYENFIYIAATYTFSGLQEGTGRPVASNKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMELLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPTRALQITDFCHRKSSRSYEVDELPVTEQELQKLKNPDTEQELEVLVRLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLSENREQLELDS", "length": 4388 }, "evidence": [ { "id": "A0A8V0ZAE9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VU08-1", "protein_name": "Intermembrane lipid transfer protein Vps13D", "gene_name": "Vps13D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRDLITWVLNTYLGKYLENLNSAQLSVALLSGEVELENIPIRKDALRSFNLPVEVTAGSIRKIKLQIPVRQFRTSPWCISIEGLFCIICPKNLDNWDYEKEKLQDLEYKLAVLDTAEAGWRSEKGKQMESYYFSSYNNWLKYGTNMATNIIDNIELKISDVHFRFEDIVDTGKSKICTGIKIGSLTAQSCDCDWTNGSYKMNNNEMNYKLVELKELSVYWDLLHEDIKCQSYSNQEILEKMHSTCELRSHNFIIKPICATARWKRDKCQQVIRTKDKPRVSCELLVPEVVIDISKVQRLQMLDKLSEIRQVKEVRQYRLKRPTCTVESNPIAWWKYATICHGFDFKKNEEKWLMLKENLRYMLLYKSIILNPNENLSAADKEFKAYIESDRKISDLTIMRRICFEKVFTKGFAFESQNEQGKNMLFHWFPNWMGWYANSPSTPNNEQDESLKHLEDDILVALENSLQNSSDLKSDAVFGHFSIKLLKGLVILQTEDKLNDGRNKSMEMQFNNFSAYLQLSPQLTSYTVGISLQEVYLIDKTSSDTMHNYLIKPQTGNTATPNQLVKNAALQEDILFQLQYENCNHLRFQLNIKSKGLDLIYNEDAIQWLLDFLADSNSFKYSPRNRVAKKTDFMKNWNEMFSGNEVNRKIWMFEIEIFAPRIIFLENYKVSNSLMVLLDFGKLEMRKMEVKRVIPVIESAVTENTSDDDETYLTPCSTPPASEKSGSESPTLLENPKTESFLNKNVQLEYVLHNKIYDKYLINFTNLQVLVCKYEERWQACLKTSSNFHLIDKFNINLTLEQRNIFTVDPEYPSFMLFGTCPTILIHGNEELINNCCNIMKPIIKASKEMENIYRGGNTIYASERIKNLAEDDRSRVVIEFVMDQLVIEMQSTERSIAELQIIGARAGLTKEPHETNISMSVHGLLLVDAIQSFGPDFELLVASHRHVGMDSLSGSLKHSAIVSPTSPGSPNFFDRATSPHMITKAVQNIKMGDRSTEFCDDEDSTALISVDIKIVPPNESNSMQLHTTSITFNSLDIIANQDTIIEILNFAKRTLLAQNIFPSESPESPKEATEAPVDVVDQVDHKSHNEIFFDFFRLNILLLYTIKRDKFNVGRKVGTVTLTEAKINASFQSDLSIIGSLGGIQVIDITSEAFCHPRILSVGRDQILRASDTNKQTVLSQLSNEIYSNNYNEETKSDESDAISFQSHWSDKTTCTFQMRMASASYTHCPRFLRDVNACITYFKRSLREFATSIGNKATDMAKEFVQQVRAVEQIGPVYPQRNRQDNWLDIIISSPIIILPISNTSTNVLIANLGKISCSNAVKCDSDEFNESYTIEIKNTYVYSLNIDEGEYSFNVHPAKNKDAIPILHDTAITLQLYAGYSDDNDEDKQLNRFSIKGSMVEALKVSLNRKQYELLLESIRYATNFSNEVLNESDELDQNGDIEPTANIDAESIISTTIQFSVPVFQINLQNEYHNDLINLTFKNFNVKHISKGFDKDVEVVLKSVLMEDLKSDLTSPFRNMVTSVDLEQKIKKNEMTSSSCPDLPSYCNSLKNRSSSVPSCFYNHMQVKVFGGDQKYTSSNKNELGKKKESQTLVIYKSHTGRSAQNGKLEQTSSIQFNCLNLAICVERWYTIFDFFGLVSVDNVNEKYPEEMKLVEKHIDKVCSKLKVSIRSFNFTLIRNESLLSRVNVSNAVFMILQDPYSKIVEGCLGSVSVNDLTKYGNIYKQKFLTSGTEALNFVYKKKLVDLEALNTLDTDSTLRINMSAVHYIHTKRFSTELHVFVKDLLQLQTPVIRKLKKHGSEQNMRPSKMKLVIQADSPVIVLPSSYNRNEVIIAYLGQFSLKNSFHFASDNNIISKMSATPSKDEILDVMRIDLVNINLFSGERSSMKAKADQEKDRIIIADMNFLRLGQPFFNESCFLHLQLERNLSADAHRVCPDISVQGTFSKLSGIINIQQYKLIRSFLNNNIGEQTDDIYMNYHNNSCTSIERLSTINLMPKNEVSKIVSILISIRILLEDVSLLLALNTSQSAAIEPLACIHFLKSTLEIDLFSDGSQDIDLISSNILIVDERNESDKSNENVFKNILEPSKKEVRIENSVQVEVHCRKKATFSKYTIMLNNMRVFALLSFLDQLKSYLQEDSPAPVVNNAANQIAQKPQIDTSISTEYVVNITDSEIIFAEECSRLDSNAIILKSTTVICYKPNSNIVPLSLDINHLEIFSCTLDAEEESALSIIDPFTLIIELRSNCLNILIQKHLNIRLSYVDVKLFSRMARLLPTQTSRPKNVISKADSDLEKAAPLVAMGFEISDCLYAMQINNWRINDAAIWLSQQKQNTYRNPALEMKTAVVDASLISVFIIDDCMDADVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNIDTEVSVNYYNRRLSGWEPVAETWESNLNWKYTKGHLDNKKRFEIGISSKQMLKLNVTSTFIELFHMVLKNWTNDFNDNGAKNFRQRSPFIPFALQNLSGTPLLFKPIYAPLGDLTRSDLQQVELIKNWYSVQPNETKTFDFSQKSKLRHVHSHQLNLHQIFVQIHGWTLIGPISVDKVGMFFRTTKLDSQFLTKSRIVFDISLIGSAQKLIKVKSSLGVINKLDRNVFLKMTLKGTHSDGLSSISVIKPNDELSVPLKFIDASLYVAHNTSESDAYEDTGFSNEEILWKACGKDDTRQLLAGYDTNKSILYTFVNISREIYHCKEQNLPGHKITLLPPLKINNMLCCDLMFKIHEHATGRINSSESVNIYNVNICQPLNLSITLDNFQLSGQLKIPVSHRGVIEPKLKLIDIQKRELHVRVSIQSVPGKGMELYISAPVWIINKTGLPLIYKQEGTSHTAAGQFEEHETARQVAPLMFSFSDQEGSPALVLRLGKAYGSNNMWCKSFSTHKDLADRDLRAENTKGSYAIGISVRRGRGLYACTTFVTLSPRFHLHNRSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNFAFHWPNWDQEQIICVRIPEIECCCWSKGIPIKDVQSLYINVRNEWGEMFFLRLEIISKDATFILLFTDARTLPPPIRIDNCSEVVINFSQLRSKPVWITPVRPQSSLSYVMDDPLGQQILLMEAPGGNMIEFPINNKNNIKKTLTYTNFIYIAFQGTFERSNEEENTHRQLVLGVRGKKVVIVEKNSGDRSQLWLMNSNGQLEHEGSTPPIQTNDANAVRLVLDLEKAPNPMEFTNLVVRTPNKQRVTTQTWRFENGRLMCHANMCVQSRFGESGLKPNYEAVVGRTENRASSSKQIPIGQHIVAQKLRPGSGQLELSTKMDGPISTIEICDIKIKQNSVFLTPDLLWMHASLNNRQITDKGKVSFVHEYLINVELVKGIGISIIARKPCEEIMFISLDHINCDIVQSALENSLDLNIAYIQIDNQLLDAVSPIALHTQTSNDLEETQNAVVLKLKMLPSPNKNAIIFKYLTLDLKPSTASLEEKLILKVASFLGYGKINRQNLSVQYQFENTDDKPFLQDMKRYYFENLSIGATQVRLSAFTSSKLPVELHETKKALGLTLIKFEDALIELDRYSDKLHFETMDVYRKELKKHYINQVKWHAAAILGSVDFLGNPLGFANDLSEGVSGLIFEGSVKSLVKNVTHGISNSTAKLTETLSDSLGKVVLDDHDNETRQRILELQSNTSGGHLAAGLKGLGFGLLGGVTSIVRHTYDGATSDGVPGFLSGLGKGLVGTVTKPIIGVLDLASETASAVRETSRDSHRNAPERKRLPRCVTGAPGGLLPLYSNRQSKGQQYLYLINQKNFSEKIISYEPNLWSDKEARLRLLVSTEYVRIFSLSDANPTIMFECHVSEILSCHPVVTNAGTTPTTSSRASASHYIEISTNLPKITRPRIRCRSEECAEAASRCINYAKSVFDEREHAVL", "length": 3919 }, "evidence": [ { "id": "A0A8V0ZAE9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAE9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "pmid": "" }, { "name": "positive regulation of mitophagy", "id": "GO:1901526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1203, "end_pos": 1205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1294, "end_pos": 1296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1435, "end_pos": 1437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1488, "end_pos": 1490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1807, "end_pos": 1809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1887, "end_pos": 1889, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2114, "end_pos": 2116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2229, "end_pos": 2231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2291, "end_pos": 2293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2325, "end_pos": 2327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2366, "end_pos": 2368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2466, "end_pos": 2468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2542, "end_pos": 2544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2804, "end_pos": 2806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2895, "end_pos": 2897, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2928, "end_pos": 2930, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2937, "end_pos": 2939, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3003, "end_pos": 3005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3264, "end_pos": 3266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3289, "end_pos": 3291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3408, "end_pos": 3410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3476, "end_pos": 3478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3522, "end_pos": 3524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4101, "end_pos": 4103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4330, "end_pos": 4332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE9" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 2637, "end_pos": 2677, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1761, 1767 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1203, "end_pos": 1205 }, { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 1294, "end_pos": 1296 }, { "start_pos": 1435, "end_pos": 1437 }, { "start_pos": 1488, "end_pos": 1490 }, { "start_pos": 1489, "end_pos": 1491 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 1807, "end_pos": 1809 }, { "start_pos": 1887, "end_pos": 1889 }, { "start_pos": 2114, "end_pos": 2116 }, { "start_pos": 2229, "end_pos": 2231 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"ac": "XP_025011307", "name": "ankyrin repeat and LEM domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011307" }, "gene_names": [ { "name": "ANKLE2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ] }, { "name": "ANKLE2", "type": "synonym", "evidence": [ { "id": "XP_025011307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011307" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and LEM domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6/entry#names_and_taxonomy" } ] }, { "name": "LEM domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and LEM domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025011307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011307" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025011307.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011307" } ] }, { "annotation": "Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. May regulate nuclear localization of VRK1 in non-dividing cells. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6#function" }, { "database": "UniProtKB", "id": "ARBA00056222", "url": "https://www.uniprot.org/uniprotkb/ARBA00056222#function" }, { "database": "UniProtKB", "id": "A0A8V0ZG51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG51#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKLE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6", "locus": { "chromosome": "15", 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF03020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2995383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2995383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025011307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERWAGAAGGGGWGSLWDGGWDRWPAWELLVACALIGAVGWLLRLLDGRTGGRGAPPEGLRCPTPRGEAERGRRGGSRPGEITMDAILSRLKQLSPDELREELVRAGLKCGPVTSTTRFIFEKKLAQFLLEQQGTLEEGSAWSEEAAGSAPPDGTHTALKTTAVNHSHHGSVSEEVDFGYCVGLNPPEEEAVAHTNCSAPVCGAGYAGSQGGAQTPSRDPPLYYGVCPVYDDILARNERIHVYEDRKEALQAVKMIKGSRFKAFSNREDAEKFAKGICDYFPSPSKSSLCLSPMKTGSLNRDGLCSLEMETANKERANSYKSPRTQDLTAKLRKAVEKGDISTFSELIWSNPRYLIGSGDNPTVVQEGCRYNVMHVAAKENQPAVCQLLLDTLENPEFMRLMYPDDDNAMLRNRIRYIVDLYLNTPDKMGFDTPLHFACKFGNLDVVNVLTSHPAIVKNPRNKYDQTPAEVVCERSKNKSAELKEKLREYLKGRYYVPLLRAEDNSSAPVIGAPWSPDQTDESPQAALSKYTGSPKDPVLSIRAFAGPMSPSKAEEFRRLWKTPPRERAGFFHNVRKSDLERGVERVGRELAHELGFPWVEYWEFLGCFVDLSSQEGLRKLEEYLSHREMSEKAQQETGENETCNRYKTPHPSGKSKKCCNSISVGAFLDEDDDDMSLEEIKNRQNAARNNSPPVVLKEPSIDAIGDAECEILSMERTRNIIETSAQPRHYEKGVSSSKNGFCNPVASERIIGDRKHVHDGEDCLVSPVCNLMSQFESLTFQPQAGAGESNAISEKKERILPERTSQVRIPKDWLDKTCYAVSPPSSSEPNVTGKRGETKLRTEHKMESERERLSMESGVQTNEAQQCQEPPAQKSLLKTSPTNDNSKKLFLLGERPSKLDSDVLAAIEAVQIDPQKYPAIYRWKHEVQSYSSADRQSWPSPALKGRFRSQSTAAGPPNASVYSSPGRNSPMMGSPGKHGNAASFSPDPGSPGRYSPACVNHSILKPRYFSEPPTH", "length": 1016, "header": "tr|A0A8V0ZAD6-1|A0A8V0ZAD6_CHICK Isoform 1 of Ankyrin repeat and LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ANKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZAD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6/entry#A0A8V0ZAD6-1", "sequence": { "sequence": "MERWAGAAGGGGWGSLWDGGWDRWPAWELLVACALIGAVGWLLRLLDGRTGGRGAPPEGLRCPTPRGEAERGRRGGSRPGEITMDAILSRLKQLSPDELREELVRAGLKCGPVTSTTRFIFEKKLAQFLLEQQGTLEEGSAWSEEAAGSAPPDGTHTALKTTAVNHSHHGSVSEEVDFGYCVGLNPPEEEAVAHTNCSAPVCGAGYAGSQGGAQTPSRDPPLYYGVCPVYDDILARNERIHVYEDRKEALQAVKMIKGSRFKAFSNREDAEKFAKGICDYFPSPSKSSLCLSPMKTGSLNRDGLCSLEMETANKERANSYKSPRTQDLTAKLRKAVEKGDISTFSELIWSNPRYLIGSGDNPTVVQEGCRYNVMHVAAKENQPAVCQLLLDTLENPEFMRLMYPDDDNAMLRNRIRYIVDLYLNTPDKMGFDTPLHFACKFGNLDVVNVLTSHPAIVKNPRNKYDQTPAEVVCERSKNKSAELKEKLREYLKGRYYVPLLRAEDNSSAPVIGAPWSPDQTDESPQAALSKYTGSPKDPVLSIRAFAGPMSPSKAEEFRRLWKTPPRERAGFFHNVRKSDLERGVERVGRELAHELGFPWVEYWEFLGCFVDLSSQEGLRKLEEYLSHREMSEKAQQETGENETCNRYKTPHPSGKSKKCCNSISVGAFLDEDDDDMSLEEIKNRQNAARNNSPPVVLKEPSIDAIGDAECEILSMERTRNIIETSAQPRHYEKGVSSSKNGFCNPVASERIIGDRKHVHDGEDCLVSPVCNLMSQFESLTFQPQAGAGESNAISEKKERILPERTSQVRIPKDWLDKTCYAVSPPSSSEPNVTGKRGETKLRTEHKMESERERLSMESGVQTNEAQQCQEPPAQKSLLKTSPTNDNSKKLFLLGERPSKLDSDVLAAIEAVQIDPQKYPAIYRWKHEVQSYSSADRQSWPSPALKGRFRSQSTAAGPPNASVYSSPGRNSPMMGSPGKHGNAASFSPDPGSPGRYSPACVNHSILKPRYFSEPPTH", "length": 1016, "header": "tr|A0A8V0ZAD6-1|A0A8V0ZAD6_CHICK Isoform 1 of Ankyrin repeat and LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ANKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZAD6-1" }, "locus": { "chromosome": "15", "start_pos": 1462595, "end_pos": 1446547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051052.1", "url": "https://www.ensembl.org/id/ENSGALT00010051052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030245.1", "url": "https://www.ensembl.org/id/ENSGALP00010030245.1" } ] } }, { "isoform_ac": "A0A8V0ZG51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6/entry#A0A8V0ZG51-1", "sequence": { "sequence": "MDAILSRLKQLSPDELREELVRAGLKCGPVTSTTRFIFEKKLAQFLLEQQGTLEEGSAWSEEAAGSAPPDGTHTALKTTAVNHSHHGSVSEEVDFGYCVGLNPPEEEAVAHTNCSAPVCGAGYAGSQGGAQTPSRDPPLYYGVCPVYDDILARNERIHVYEDRKEALQAVKMIKGSRFKAFSNREDAEKFAKGICDYFPSPSKSSLCLSPMKTGSLNRDGLCSLEMETANKERANSYKSPRTQDLTAKLRKAVEKGDISTFSELIWSNPRYLIGSGDNPTVVQEGCRYNVMHVAAKENQPAVCQLLLDTLENPEFMRLMYPDDDNAMLRNRIRYIVDLYLNTPDKMGFDTPLHFACKFGNLDVVNVLTSHPAIVKNPRNKYDQTPAEVVCERSKNKSAELKEKLREYLKGRYYVPLLRAEDNSSAPVIGAPWSPDQTDESPQAALSKYTGSPKDPVLSIRAFAGPMSPSKAEEFRRLWKTPPRERAGFFHNVRKSDLERGVERVGRELAHELGFPWVEYWEFLGCFVDLSSQEGLRKLEEYLSHREMSEKAQQETGENETCNRYKTPHPSGKSKKCCNSISVGAFLDEDDDDMSLEEIKNRQNAARNNSPPVVLKEPSIDAIGDAECEILSMERTRNIIETSAQPRHYEKGVSSSKNGFCNPVASERIIGDRKHVHDGEDCLVSPVCNLMSQFESLTFQPQAGAGESNAISEKKERILPERTSQVRIPKDWLDKTCYAVSPPSSSEPNVTGKRGETKLRTEHKMESERERLSMESGVQTNEAQQCQEPPAQKSLLKTSPTNDNSKKLFLLGERPSKLDSDVLAAIEAVQIDPQKYPAIYRWKHEVQSYSSADRQSWPSPALKGRFRSQSTAAGPPNASVYSSPGRNSPMMGSPGKHGNAASFSPDPGSPGRYSPACVNHSILKPRYFSEP", "length": 930, "header": "tr|A0A8V0ZG51-1|A0A8V0ZG51_CHICK Computationally mapped isoform of Ankyrin repeat and LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ANKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZAD6-1" }, "locus": { "chromosome": "15", "start_pos": 1458269, "end_pos": 1446556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051066.1", "url": "https://www.ensembl.org/id/ENSGALT00010051066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030257.1", "url": "https://www.ensembl.org/id/ENSGALP00010030257.1" } ] } }, { "isoform_ac": "A0A8V0ZHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6/entry#A0A8V0ZHG3-1", "sequence": { "sequence": "MERWAGAAGGGGWGSLWDGGWDRWPAWELLVACALIGAVGWLLRLLDGRTGGRGAPPEGLRCPTPRGEAERGRRGGSRPGEITMDAILSRLKQLSPDELREELVRAGLKCGPVTSTTRFIFEKKLAQFLLEQQGTLEEGSAWSEEAAGSAPPDGTHTALKTTAVNHSHHGSVSEEVDFGYCVGLNPPEEEAVAHTNCSAPVCGAGYAGSQGGAQTPSRDPPLYYGVCPVYDDILARNERIHVYEDRKEALQAVKMIKGSRFKAFSNREDAEKFAKGICDYFPSPSKSSLCLSPMKTGSLNRDGLCSLEMETANKERANSYKSPRTQDLTAKLRKAVEKGDISTFSELIWSNPRYLIGSGDNPTVVQEGCRYNVMHVAAKENQPAVCQLLLDTLENPEFMRLMYPDDDNAMLRNRIRYIVDLYLNTPDKMGFDTPLHFACKFGNLDVVNVLTSHPAIVKNPRNKYDQTPAEVVCERSKNKSAELKEKLREYLKGRYYVPLLRAEDNSSAPVIGAPWSPDQTDESPQAALSKYTGSPKDPVLSIRAFAGPMSPSKAEEFRRLWKTPPRERAGFFHNVRKSDLERGVERVGRELAHELGFPWVEYWEFLGCFVDLSSQEGLRKLEEYLSHREMSEKAQQETGENETCNRYKTPHPSGKSKKCCNSISVGAFLDEDDDDMSLEEIKNRQNAARNNSPPVVLKEPSIDAIGDAECEILSMERTRNIIETSAQPRHYEKGVSSSKNGFCNPVASERIIGDRKHVHDGEDCLVSPVCNLMSQFESLTFQPQAGAGESNAISEKKERILPERTSQVRIPKDWLDKTCYAVSPPSSSEPNVTGKRGETKLRTEHKMESERERLSMESGVQTNEAQQCQEPPAQKSLLKTSPTNDNSKKLFLLGERPSKLDSDVLAAIEAVQIDPQKYPAIYRWKHEVQSYSSADRQRGDVQLEKPTTKPRW", "length": 952, "header": "tr|A0A8V0ZHG3-1|A0A8V0ZHG3_CHICK Computationally mapped isoform of Ankyrin repeat and LEM domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ANKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZAD6-1" }, "locus": { "chromosome": "15", "start_pos": 1462595, "end_pos": 1446059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051068.1", "url": "https://www.ensembl.org/id/ENSGALT00010051068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030259.1", "url": "https://www.ensembl.org/id/ENSGALP00010030259.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416790", "resource": "KEGG Pathway" }, { "id": "R-GGA-2995383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2995383", "resource": "Reactome", "description": "Initiation of Nuclear Envelope (NE) Reformation" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6P1H6-1", "protein_name": "Ankyrin repeat and LEM domain-containing protein 2", "gene_name": "Ankle2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWQRLAVVEWAALAWELLGASVLFIAVRWLVRRLEKRPRDLNRCGTLSSPPSASEAVAAQPGEVTMDAMMARLKLLNPDDLRKEVMKAGLKCGPITSTTRFIFEKKLAQALLEQGGLLTSSLPKPSAVTAMAFIQGTSRTPPSVDGKQTQQACFSEDRDFGYSVGLNPPEEEAVASSVHPVPFSASTRNDNHKAGVTAPKEPLVYYGVCPVYEDGPVRHERIHVYEDKKEALQAAKLIKGSRFKAFRTREDAEKFARGICDYLPSPNKTTPLLSPVKAVPLGGSDGLKADGLCLAESETVNKERANSYKNPRTQDLTAKLRKAVENGEEHTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASMCQLTLETLENPEFMRLMYPDDNMDMLQKRILYVVDLYLNTPDKVGFDTPLHFACKFGNVDVVNVLSSHPLIVKNRKNKYGKTPEEVICERSQNKSPALKERIREYLMGHYYVPLLRAEDTSPVIGELWSSDQKAEASNTAHCRSSPRDPVMTLRAFVGPLSPSKAEDFRKLWKTPPRKKAGFFHSIRKSDPERGIERVGRELAHELGYPWVEYWEFLGCFVDLSSQEGLQRLEEYLIQKELSKKAQQEIRENEGCLQDRTSDFGSGKKYSNSISVGAFLDGDDDSSLEEIKNQQNTVPSQSQPTTDKFQTSKSGSLPLGQKVDPGETSVGTYPDKGRNGFCHPLNHRTADGRGLEATNGEEALPPPVSVLTQELNKLNLQSLGDSLHETPDKNGKLEDEVLPSRKGAADSDLLASPPAIASLGKKQVRTNTEVSEAMAEMSLGPKSPQLGVQAGLEPILSSATVDSTKRLFLSGEEPSKLDRDVLAALECANIDPGLYPAIHRWKSTVMCYSPSDRQSWPSPALKGKFTTELVDLDCSHSCSGRCSPAGSSPSKPGHTSSSSGLHSPGRYSPAHGRHFQRVAHVARLAAL", "length": 964 }, "evidence": [ { "id": "A0A8V0ZAD6", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TP65-1", "protein_name": "Ankyrin repeat and LEM domain-containing protein 2", "gene_name": "Ankle2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWQRLAVVEWAALAWELLGASVLLIAVRWLVRRLENLSRDPNRCGTLSSLPGASAAVSAQPGEVMTMDAMLARLKLLNPDDLRQEVMKAGLKCGPITSTTRFIFEKKLAQALLEQGGLLTSSLPKHSEVTGTAFIHGTSRTPAFVDRKQTQQACLSEDRDFGYSVGLNPPEEEAVTSSVHPIPFSASTRNDNHKAGVTTAKEPLLYYGVCPVYEDGLVRHERIHVYEDKKEALQAVKLIKGSRFKAFPTREDAEKFARGICDYLPSPSKNMSLLSPVKAMPLCSNDGPKADGLCLAESETVNKERANSYKNPRTQDLTAKLRKAVERGEEHTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASVCQLTLETLENPEFMRLMYPDDNMDMLQKRILYIVDLYLNTPDKVGFDTPLHFACKFGNVDVVNVLSSHPLIVKNPRNKYGKTPEDVICERSKNKSVELRERIREYLMGHYYVPLLRAEDTSPVIGELWSSDQKAEASSADHCRSSPRDPVMTLRAFVGPLSPSKAEDFRKLWKTPPRKKAGLFHSIRKSDPERGIERVGRELAHELGYPWVEYWEFLGCFVDLSSQEGLQRLEEYLIQKELNQKAQHEIGEEEGCLQDRTSDFGSGKKYSNSISVGAFLDGGDDISLEEVKNQQNTVPSQSQPSVDKFQNSKSGSPSLGQKADPGEAAVGFYPDNSRNGFCYPLNSRTADGRETEATNGEEALPPPVSILTQEFDKLNLQSLGDNLFETPNKNRELEDKILASSKGVVESGLASPAAIARLENKQVRTNSEVSEAMAEMSLGPNSPQLGVQAGLEPGFSSATADPTKRLFLSGEEPSKLDRDVLAALECAIIDPGLYPAVHRWKSTVMGYSPSDRQSWPSPALKGKFTTELVDLDCCHSCSGRSSPAGSSPSKPGHTTFSSGLHSPGRYSPAHGRHFQRVACMARLAAL", "length": 964 }, "evidence": [ { "id": "A0A8V0ZAD6", "url": "https://omabrowser.org/oma/group/A0A8V0ZAD6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "mitotic nuclear membrane reassembly", "id": "GO:0007084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007084", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" }, { "name": "protein phosphatase 2A binding", "id": "GO:0051721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 959, "end_pos": 961, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD6" }, { "id": "PS50954", "database": "PROSITE", 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142826.1. 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"url": "https://www.ncbi.nlm.nih.gov/gene/423287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DSCAEDR", "url": "https://omabrowser.org/oma/group/DSCAEDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZAF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG56", "url": "https://www.orthodb.org/?gene=A0A8V0ZG56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14682:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14682:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13925", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13925", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEAHNAKKQKVLHIEGRPVDLPRKAISSSTKKIMKEDKKAPKQLASYTNRITVGKTVTSPLSLFKAVHCKRKVHCYTAKPCYKRKQFPKSRGCNMANKENELACAGNLPAKLNDSRTHLLNSGDSGSSQTEGPSSKYSAFFSEVSQDHETMAQVLFSRNLRLNVALTFWRRRSISELVAYLLRIQDLGVVVDCLPVLTNSLQEEKPYISVGCCVDLLPLVKSLLKSKYEEYVIVGLNWLQAVIKRWWSELSAHKERAEDGNMIILKQQLSELWEQEHHLTLVPGYTGNIAKEVNAYLLQLC", "length": 303, "header": "tr|A0A8V0ZAG1-1|A0A8V0ZAG1_CHICK Isoform 1 of Katanin regulatory subunit B1 like 1 OS=Gallus gallus OX=9031 GN=KATNBL1 PE=4 SV=1 CANONICAL=A0A8V0ZAG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1/entry#A0A8V0ZAF6-1", "sequence": { "sequence": "MASEAHNAKKQKVLHIEGRPVDLPRKAISSSTKKIMKEVSFTKILVYFCRITVGKTVTSPLSLFKAVHCKRKVHCYTAKPCYKRKQFPKSRGCNMANKENELACAGNLPAKLNDSRTHLLNSGDSGSSQTEGPSSKYSAFFSEVSQDHETMAQVLFSRNLRLNVALTFWRRRSISELVAYLLRIQDLGVVVDCLPVLTNSLQEEKPYISVGCCVDLLPLVKSLLKSKYEEYVIVGLNWLQAVIKRWWSELSAHKERAEDGNMIILKQQLSELWEQEHHLTLVPGYTGNIAKLC", "length": 293, "header": "tr|A0A8V0ZAF6-1|A0A8V0ZAG1_CHICK Computationally mapped isoform of Katanin regulatory subunit B1 like 1 OS=Gallus gallus OX=9031 GN=KATNBL1 PE=4 SV=1 CANONICAL=A0A8V0ZAG1-1" }, "locus": { "chromosome": "5", "start_pos": 29523570, "end_pos": 29517755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051069.1", "url": "https://www.ensembl.org/id/ENSGALT00010051069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030260.1", "url": "https://www.ensembl.org/id/ENSGALP00010030260.1" } ] } }, { "isoform_ac": "A0A8V0ZAG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1/entry#A0A8V0ZAG1-1", "sequence": { "sequence": "MASEAHNAKKQKVLHIEGRPVDLPRKAISSSTKKIMKEDKKAPKQLASYTNRITVGKTVTSPLSLFKAVHCKRKVHCYTAKPCYKRKQFPKSRGCNMANKENELACAGNLPAKLNDSRTHLLNSGDSGSSQTEGPSSKYSAFFSEVSQDHETMAQVLFSRNLRLNVALTFWRRRSISELVAYLLRIQDLGVVVDCLPVLTNSLQEEKPYISVGCCVDLLPLVKSLLKSKYEEYVIVGLNWLQAVIKRWWSELSAHKERAEDGNMIILKQQLSELWEQEHHLTLVPGYTGNIAKEVNAYLLQLC", "length": 303, "header": "tr|A0A8V0ZAG1-1|A0A8V0ZAG1_CHICK Isoform 1 of Katanin regulatory subunit B1 like 1 OS=Gallus gallus OX=9031 GN=KATNBL1 PE=4 SV=1 CANONICAL=A0A8V0ZAG1-1" }, "locus": { "chromosome": "5", "start_pos": 29524340, "end_pos": 29517755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051074.1", "url": "https://www.ensembl.org/id/ENSGALT00010051074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030265.1", "url": "https://www.ensembl.org/id/ENSGALP00010030265.1" } ] } }, { "isoform_ac": "A0A8V0ZG56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1/entry#A0A8V0ZG56-1", "sequence": { "sequence": "MASEAHNAKKQKVLHIEGRPVDLPRKAISSSTKKIMKEDKKAPKQLASYTNRITVGKTVTSPLSLFKAVHCKRKVHCYTAKPCYKRKQFPKSRGCNMANKENELACAGNLPAKLNDSRTHLLNSGDSGSSQTEGPSSKYSAFFSEVSQDHETMAQVLFSRNLRLNVALTFWRRRSISELVAYLLRIQDLGVVVDCLPVLTNSLQEEKPYISVGCCVDLLPLVKSLLKSKYEEYVIVGLNWLQAVIKRWWSELSAHKERAEDGNMIILKQQLSELWEQEHHLTLVPGYTGNIAKVIQLLSNKYSYTIYTCSIPLTGCNLL", "length": 319, "header": "tr|A0A8V0ZG56-1|A0A8V0ZG56_CHICK Computationally mapped isoform of Katanin regulatory subunit B1 like 1 OS=Gallus gallus OX=9031 GN=KATNBL1 PE=4 SV=1 CANONICAL=A0A8V0ZAG1-1" }, "locus": { "chromosome": "5", "start_pos": 29522862, "end_pos": 29517755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051071.1", "url": "https://www.ensembl.org/id/ENSGALT00010051071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030262.1", "url": "https://www.ensembl.org/id/ENSGALP00010030262.1" } ] } }, { "isoform_ac": "A0A8V0ZHI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1/entry#A0A8V0ZHI9-1", "sequence": { "sequence": "MASEAHNAKKQKVLHIEGRPVDLPRKAISSSTKKIMKEDKKAPKQLASYTNRITVGKTVTSPLSLFKAVHCKRKVHCYTAKPCYKRKQFPKSRGCNMANKENELACAGNLPAKLNDSRTHLLNSGDSGSSQTEGPSSKYSAFFSEVSQDHETMAQVLFSRNLRLNVALTFWRRRSISELVAYLLRIQDLGVVVDCLPVLTNSLQEEKPYISVGCCVDLLPLVKSLLKSKYEEYVIVGLNWLQAVIKRWWSELSAHKERAEDGNMIILKQQLSELWEQEHHLTLVPGYTGNIAKMPISRRVEIILVEAGSRTCAGERAFERRERYCSNLPLIGHIRVLGSIEHL", "length": 343, "header": "tr|A0A8V0ZHI9-1|A0A8V0ZHI9_CHICK Computationally mapped isoform of Katanin regulatory subunit B1 like 1 OS=Gallus gallus OX=9031 GN=KATNBL1 PE=4 SV=1 CANONICAL=A0A8V0ZAG1-1" }, "locus": { "chromosome": "5", "start_pos": 29536178, "end_pos": 29517755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051072.1", "url": "https://www.ensembl.org/id/ENSGALT00010051072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030263.1", "url": "https://www.ensembl.org/id/ENSGALP00010030263.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B1WBZ9-1", "protein_name": "Katanin regulatory subunit B1 like 1", "gene_name": "Katnbl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFDTHHVKKRNFSNSIDLPRKRISNFTSKNMKEVKISPKQLAAYISRTVGQAVKSPDKLRKVLYHRKLVRHSFPNPCYKTKQSPRSGGCDMANKENELACAGHLPENLHHDSRTFVINTSDSGSSQTENPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSVSELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQCISLGCCVDLFPLVKSLLQSRFEEYVIVGLNWLQAVIKRWWSELSSKSEIISDGNIKILKQQLNGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "length": 299 }, "evidence": [ { "id": "A0A8V0ZAG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SCL5-1", "protein_name": "Katanin regulatory subunit B1 like 1", "gene_name": "KATNBL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASETHNVKKCNSCNNIEDHSIDLPRKRISNFTNKNMKEVKKSPKQLAAYITRTVGQAVKSPDKLRKVIYRRKKVHHPFPNPCYRRKQSPRSGGCDMANKENELACAGHLPEKLRHDSRTYSVNSSDSSSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSISELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQYISLGCCVDLLPLVKSLLKSKFEEYVIVGLNWLQAVIKRWWSELSSKTEIINDGNIQILKQQLSGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "length": 304 }, "evidence": [ { "id": "A0A8V0ZAG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HIG9-1", "protein_name": "KATNB1-like protein 1", "gene_name": "Katnbl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASDTHHVKKRNFSNSVEDHPIDLPRKRISNFTSKNMKEVKKSPKQLAAYISRTVGQAVKSPDKLRKVLYHRKLVRHPFPNPCYRTKQSPKSGGCDMANKENELACAGHLPENLRHDSRTFVVNASDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSISELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQYISLGCCVDLLPLVKSLLQSKFEEYVIVGLNWLQAVIKRWWSELSSKSEITSDGNIKILKQQLNGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "length": 304 }, "evidence": [ { "id": "A0A8V0ZAG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9CWJ3-1", "protein_name": "KATNB1-like protein 1", "gene_name": "Katnbl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFDTHHVKKRNFSNSIDLPRKRISNFTSKNMKEVKRSPKQLAAYISRTVAQAVKSPEKLRKVLYHRKLVRRSFPNPCYKTKQSPKSGGCDMANKENELACAGHLPENLRHDSRTFVINTSDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSISELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQYISLGCCVDLLPLVKSLLQSRFEEYVIVGLNWLQAVIKRWWSELSSTSEIISDGNIKILKQQLSGLWEQESHLTLVPGYTGNIAKDVDAYLLQLH", "length": 299 }, "evidence": [ { "id": "A0A8V0ZAG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H079-1", "protein_name": "KATNB1-like protein 1", "gene_name": "KATNBL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASETHNVKKRNFCNKIEDHFIDLPRKKISNFTNKNMKEVKKSPKQLAAYINRTVGQTVKSPDKLRKVIYRRKKVHHPFPNPCYRKKQSPGSGGCDMANKENELACAGHLPEKLHHDSRTYLVNSSDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNMRLNVALTFWRKRSISELVAYLLRIEDLGVVVDCLPVLTNCLQEEKQYISLGCCVDLLPLVKSLLKSKFEEYVIVGLNWLQAVIKRWWSELSSKTEIINDGNIQILKQQLSGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "length": 304 }, "evidence": [ { "id": "A0A8V0ZAG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cytoskeleton organization", "id": "GO:0051495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG1" }, { "id": "PF13925", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13925" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Katanin p80 subunit C-terminal", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 299, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAG9-1", "uniprot_ac": "A0A8V0ZAG9", "uniprot_id": "A0A8V0ZAG9_CHICK", "mass": { "chemical_mass": 42433.0, "monoisotopic_mass": 42433.0 }, "refseq": { "ac": "XP_004936498", "name": "snRNA-activating protein complex subunit 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936498" }, "gene_names": [ { "name": "SNAPC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ] }, { "name": "SNAPC1", "type": "synonym", "evidence": [ { "id": "XP_004936498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936498" } ] } ], "protein_names": [ { "name": "Small nuclear RNA activating complex polypeptide 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9/entry#names_and_taxonomy" } ] }, { "name": "snRNA-activating protein complex subunit 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004936498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936498" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936498.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936498" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNAPC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9", "locus": { "chromosome": "5", "start_pos": 53466709, "end_pos": 53475319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017779", "url": "https://www.ensembl.org/id/ENSGALG00010017779" } ] } } ], "crossref": [ { "id": "A0A8V0ZAG9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "423517", "url": "https://www.ncbi.nlm.nih.gov/gene/423517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423517", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423517", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDDMQNV", "url": "https://omabrowser.org/oma/group/RDDMQNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z301", "url": "https://www.orthodb.org/?gene=A0A8V0Z301", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3H4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAG9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15131:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15131:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09808", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09808", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76071", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z301", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z301", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z301-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z301-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGVPGLQEDCEALLGAFQEADTVRFERFAELWRERRFHTIFHGRMRALERNKITKKTLELAQQYFLPPYAFQIRVGALYLLYGLYNTQLCQPKIQIRIALKDWPEVQSFQQDLIDSQHYDAAYIFRTLRRARAFHFTAMPKLLNYRTKKKIQENECKEEFKDPSNRVSSLITNDVLEELMNIHEHYQKMKCAISADKSQPDKALSLIKDEFVVSLKDIALEHQEWQQKRLKFLLKAKETDEMPNRVEEETSLRSEGSERADALARIKHKSYSAVVEASKSRRHRQVILESSESGSDYGKSPRRSKKSSRRPQPAEKRGSLEIRGQIQAEKETVTCHIGMPVITEEDSSDTEEVPLSKRRRRR", "length": 363, "header": "tr|A0A8V0ZAG9-1|A0A8V0ZAG9_CHICK Isoform 1 of Small nuclear RNA activating complex polypeptide 1 OS=Gallus gallus OX=9031 GN=SNAPC1 PE=4 SV=1 CANONICAL=A0A8V0ZAG9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z301-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9/entry#A0A8V0Z301-1", "sequence": { "sequence": "MSGVPGLQEDCEALLGAFQEADTVRFERFAELWRERRFHTIFHGRMRALERNKITKKTLELAQQYFLPPYAFQIRVGALYLLYGLYNTQLCQPKIQIRIALKDWPEVQSFQQDLIDSQHYDAAYIFRTLRRARAFHFTAMPKLLNYRTKKKIQENECKEEFKDPSNRVSSLITNDVLEELMNIHEHYQKMKCAISADKSQPDKALSLIKDEFVVSLKDIALEHQEWQQKRLKFLLKAKETDEMPNRVEEETSLRSEGSERADALARIKHKSYSAVVEASKSRRHRQVILESSESGSDYGKSPRRSKKSSRRPQPAEKRGQIQAEKETVTCHIGMPVITEEDSSDTEEVPLSKRRRRR", "length": 357, "header": "tr|A0A8V0Z301-1|A0A8V0Z301_CHICK Computationally mapped isoform of Small nuclear RNA activating complex polypeptide 1 OS=Gallus gallus OX=9031 GN=SNAPC1 PE=4 SV=1 CANONICAL=A0A8V0ZAG9-1" }, "locus": { "chromosome": "5", "start_pos": 53475196, "end_pos": 53467601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042969.1", "url": "https://www.ensembl.org/id/ENSGALT00010042969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025459.1", "url": "https://www.ensembl.org/id/ENSGALP00010025459.1" } ] } }, { "isoform_ac": "A0A8V0Z3H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9/entry#A0A8V0Z3H4-1", "sequence": { "sequence": "MSGVPGLQEDCEALLGAFQEADTVRFERFAELWRERRFHTIFHGRMRALERNKITKKTLELAQQYFLPPYAFQIRVGALYLLYGLYNTQLCQPKIQIRIALKDWPEVQSFQQDLIDSQHYDAAYIFRTLRRARAFHFTAMPKLLNYRTKKKIQENECKEEFKDPSNRVSSLITNDVLEELMNIHEHYQKMKCAISADKSQPDKALSLIKDEFVVSLKDIALEHQEWQQKRLKFLLKAKETDEMPNRVEEETSLRSEGSERADALARIKHKSYSAVVEASKSRRHRQVILESSESGSDYGKSPRRSKKSSRRPQPAEKRGSLEIRGSFPLHLGRNSLL", "length": 337, "header": "tr|A0A8V0Z3H4-1|A0A8V0Z3H4_CHICK Computationally mapped isoform of Small nuclear RNA activating complex polypeptide 1 OS=Gallus gallus OX=9031 GN=SNAPC1 PE=4 SV=1 CANONICAL=A0A8V0ZAG9-1" }, "locus": { "chromosome": "5", "start_pos": 53475196, "end_pos": 53469684, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042966.1", "url": "https://www.ensembl.org/id/ENSGALT00010042966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025456.1", "url": "https://www.ensembl.org/id/ENSGALP00010025456.1" } ] } }, { "isoform_ac": "A0A8V0ZAG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9/entry#A0A8V0ZAG9-1", "sequence": { "sequence": "MSGVPGLQEDCEALLGAFQEADTVRFERFAELWRERRFHTIFHGRMRALERNKITKKTLELAQQYFLPPYAFQIRVGALYLLYGLYNTQLCQPKIQIRIALKDWPEVQSFQQDLIDSQHYDAAYIFRTLRRARAFHFTAMPKLLNYRTKKKIQENECKEEFKDPSNRVSSLITNDVLEELMNIHEHYQKMKCAISADKSQPDKALSLIKDEFVVSLKDIALEHQEWQQKRLKFLLKAKETDEMPNRVEEETSLRSEGSERADALARIKHKSYSAVVEASKSRRHRQVILESSESGSDYGKSPRRSKKSSRRPQPAEKRGSLEIRGQIQAEKETVTCHIGMPVITEEDSSDTEEVPLSKRRRRR", "length": 363, "header": "tr|A0A8V0ZAG9-1|A0A8V0ZAG9_CHICK Isoform 1 of Small nuclear RNA activating complex polypeptide 1 OS=Gallus gallus OX=9031 GN=SNAPC1 PE=4 SV=1 CANONICAL=A0A8V0ZAG9-1" }, "locus": { "chromosome": "5", "start_pos": 53475196, "end_pos": 53467601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042973.1", "url": "https://www.ensembl.org/id/ENSGALT00010042973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025463.1", "url": "https://www.ensembl.org/id/ENSGALP00010025463.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423517", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-76071", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76071", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 3 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BH65-1", "protein_name": "Small nuclear RNA activating complex polypeptide 1", "gene_name": "SNAPC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTPAGLQTDCEALLSRFQKMDSVRFEDFTELWRKMKFGTIFCGKMRHLEKNTFTKEALALAWRYFLPPYAFQIRVGALYLLYGLYNAQLCQPKQKIRVALKDWDEILKFQQDLINAQHFDAAYIFRKLRLDRAFHFAAMPKLLSYRMKKKIQRAEVTEEFKDPNDRVMKLITSDVLEEMLNVHDHYQRMKQIISGDKSNPDKALSLIKDDFFENIKNIVLEHQQWHKDRKNPPLKSKVKDGEEKSEGNSQQSERCERAESLARIKSKAFSVVVQASKSRRHRQVKRDSSDSDSASGQGQIKATRKKRNKETLKSAGRKRTATNRGDTQNAHNKEDKSLSLSMPVITEEEEENESFSETEFTAPKRRRKQRTKSLM", "length": 376 }, "evidence": [ { "id": "A0A8V0ZAG9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LXW8-1", "protein_name": "Small nuclear RNA activating complex, polypeptide 1", "gene_name": "Snapc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHGARERDVSGRCYRSLFLVAGMAQQGRSMEAPAGSSTRPMGAGTLEGVGIPPGLQTDCETLLSRFQEMDSVRFEDFAELWRSMKFATIFCGKMRNLKKNMFTREALALAWCYFLPPYTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVIKFQQDLISAQHFDAAFVFRKLRLDRAFHFTAMPKLLSCRMKKKAQQAEVTQKFKDPNDRVMKLITSDVLEEMLNVHDHYQNMKHAISADKSTPDRALSLVKEDFFDNIKNIVLEHQDWHKERKNPSLKPKLKDGEEDGEGPSEEPERCERAVSLAKIKAKAFSAVAQVSKSRRHRQSKLDSSDSDSGSGQVQGKATKRKRTREPAEPAGRKQRPSRSKGDVPNERKEEKSLRLSMPVITEEEEESSDGLSKAEFTAPKRKRKH", "length": 420 }, "evidence": [ { "id": "A0A8V0ZAG9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HZ05-1", "protein_name": "snRNA-activating protein complex subunit 1", "gene_name": "Snapc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METAADAGTRPVGAGTLAGAGTPPGLQTDCEALLSRFQELDSVRFEDFAELWRSMKFATIFCGKMRNLKKNMFTKEALALAWRYFLPPYTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVNKFQQDLINAQHFDAAFIFRNLRLDRAFHFTAMPKLLSCRMKKKIQQTEVTQKFKDPSDRVMKLITSDVLEEMLNVHDHYQNMKRAISADKSMPDKALSLVKEDFFDNIKNIVLEHQQWHKDRKNPTLKPKLKEGEEDSEGPSQEPERCERAESLAKIKAKAFSAVAQASKSRRHRQAKLDSSDSDSGSGQGQGKAAKKKRTRETAAEPRGRKRASRSRGNVQNERKEEKSLCLSMPIIAEEEEETDNFSEAEFTAPKRKRKR", "length": 389 }, "evidence": [ { "id": "A0A8V0ZAG9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q16533-1", "protein_name": "snRNA-activating protein complex subunit 1", "gene_name": "SNAPC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTPPGLQTDCEALLSRFQETDSVRFEDFTELWRNMKFGTIFCGRMRNLEKNMFTKEALALAWRYFLPPYTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVLKFQQDLVNAQHFDAAYIFRKLRLDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPSDRVMKLITSDVLEEMLNVHDHYQNMKHVISVDKSKPDKALSLIKDDFFDNIKNIVLEHQQWHKDRKNPSLKSKTNDGEEKMEGNSQETERCERAESLAKIKSKAFSVVIQASKSRRHRQVKLDSSDSDSASGQGQVKATRKKEKKERLKPAGRKMSLRNKGNVQNIHKEDKPLSLSMPVITEEEENESLSGTEFTASKKRRKH", "length": 368 }, "evidence": [ { "id": "A0A8V0ZAG9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K0S9-1", "protein_name": "snRNA-activating protein complex subunit 1", "gene_name": "Snapc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTPAGAGTRPTGAGTVEGVGIPPGLQTDYETLLSRFQEMDSVRFEDFTELWRSMKFATIFCGKMRNLKKNMFTKEALALAWRYFLPPHTFQIRVGALYLLYGLYNTQLCQPKQKIRVALKDWDEVIRFQQDLMNAQHFDAAFVFRKLRLDRAFHFTAMPKLLSCRMKKKVQQTEVTQKFKDPNDRVMKLITSDVLEEMLNVHDHYQNMKHAISADKSMPDRALSLVKEDFFENIKNIVLEHQEWHKERKNPSLKPKLKDGEENGEGSSEEPERCERAVSLAKIKAKAFSAVVPVSKSRRHRQSKLDSSDSDSGSGQVQGRAAKRKRTREPAGPAGRKRSSRSKGNAPNERKEEKSLHLSMPIITEEEEEDMGGVRKAEFTAPKRKRKC", "length": 389 }, "evidence": [ { "id": "A0A8V0ZAG9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" }, { "name": "snRNA-activating protein complex", "id": "GO:0019185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAH0-1", "uniprot_ac": "A0A8V0ZAH0", "uniprot_id": "A0A8V0ZAH0_CHICK", "mass": { "chemical_mass": 22598.0, "monoisotopic_mass": 22598.0 }, "refseq": {}, "gene_names": [ { "name": "HESC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH0" } ] } ], "protein_names": [ { "name": "Transcription factor HES-5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH0/entry#names_and_taxonomy" } ] }, { "name": "Hairy and enhancer of split 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAH0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional repressor of genes that require a bHLH protein for their transcription. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ELSTGLKLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 267, "header": "tr|A0A8V0ZAK5-1|A0A8V0ZAK5_CHICK Isoform 1 of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZAK5-1", "sequence": { "sequence": "ELSTGLKLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 267, "header": "tr|A0A8V0ZAK5-1|A0A8V0ZAK5_CHICK Isoform 1 of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13653839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051114.1", "url": "https://www.ensembl.org/id/ENSGALT00010051114.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030305.1", "url": "https://www.ensembl.org/id/ENSGALP00010030305.1" } ] } }, { "isoform_ac": "A0A8V0ZAN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZAN0-1", "sequence": { "sequence": "DFPDKNIQLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 268, "header": "tr|A0A8V0ZAN0-1|A0A8V0ZAN0_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13589458, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051139.1", "url": "https://www.ensembl.org/id/ENSGALT00010051139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030330.1", "url": "https://www.ensembl.org/id/ENSGALP00010030330.1" } ] } }, { "isoform_ac": "A0A8V0ZHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZHL8-1", "sequence": { "sequence": "SILTSLPTCLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 269, "header": "tr|A0A8V0ZHL8-1|A0A8V0ZHL8_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13650448, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051118.1", "url": "https://www.ensembl.org/id/ENSGALT00010051118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030309.1", "url": "https://www.ensembl.org/id/ENSGALP00010030309.1" } ] } }, { "isoform_ac": "A0A8V0ZHM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZHM4-1", "sequence": { "sequence": "MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRAKGSSRVCWLLCCSEGIPMRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 288, "header": "tr|A0A8V0ZHM4-1|A0A8V0ZHM4_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13643752, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051123.1", "url": "https://www.ensembl.org/id/ENSGALT00010051123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030314.1", "url": "https://www.ensembl.org/id/ENSGALP00010030314.1" } ] } }, { "isoform_ac": "A0A8V0ZHP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZHP4-1", "sequence": { "sequence": "NEARTTATRDGKTPLCCQGNATKARGRAGQQLASAGTFRVVKEPLAFLRVLEWLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 313, "header": "tr|A0A8V0ZHP4-1|A0A8V0ZHP4_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13594708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051138.1", "url": "https://www.ensembl.org/id/ENSGALT00010051138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030329.1", "url": "https://www.ensembl.org/id/ENSGALP00010030329.1" } ] } }, { "isoform_ac": "A0A8V0ZHP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZHP9-1", "sequence": { "sequence": "RWDVPKVSPAEQLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 272, "header": "tr|A0A8V0ZHP9-1|A0A8V0ZHP9_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13595576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051134.1", "url": "https://www.ensembl.org/id/ENSGALT00010051134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030323.1", "url": "https://www.ensembl.org/id/ENSGALP00010030323.1" } ] } }, { "isoform_ac": "A0A8V0ZHQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZHQ4-1", "sequence": { "sequence": "AVGSLRLSVLLVSGDEELFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 277, "header": "tr|A0A8V0ZHQ4-1|A0A8V0ZHQ4_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13636967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051137.1", "url": "https://www.ensembl.org/id/ENSGALT00010051137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030328.1", "url": "https://www.ensembl.org/id/ENSGALP00010030328.1" } ] } }, { "isoform_ac": "A0A8V0ZNN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZNN0-1", "sequence": { "sequence": "MASDEHQCYHNELFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 272, "header": "tr|A0A8V0ZNN0-1|A0A8V0ZNN0_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13649233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051120.1", "url": "https://www.ensembl.org/id/ENSGALT00010051120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030311.1", "url": "https://www.ensembl.org/id/ENSGALP00010030311.1" } ] } }, { "isoform_ac": "A0A8V0ZNN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZNN4-1", "sequence": { "sequence": "KRYGTRWVIPCCSPLCSCWTCVLHLTSQLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 288, "header": "tr|A0A8V0ZNN4-1|A0A8V0ZNN4_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13641626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051125.1", "url": "https://www.ensembl.org/id/ENSGALT00010051125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030316.1", "url": "https://www.ensembl.org/id/ENSGALP00010030316.1" } ] } }, { "isoform_ac": "A0A8V0ZNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5/entry#A0A8V0ZNN9-1", "sequence": { "sequence": "MTLLSVHLTTLFAIFAFATCGGYSGGLRLSVDCANKSESDLNIDIAFAYPFRLHQVNFDAPTCEGKRRETLSLIGDFSSSAEFFVTIAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKIATDPDEVLLLMSACKQQSNKCLPVRSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRHAADTMEKQSSGYNQGGYNQDSYGPAGGYNQPGSYGQVGDYGQPQSYGQSGPTSFANQI", "length": 270, "header": "tr|A0A8V0ZNN9-1|A0A8V0ZNN9_CHICK Computationally mapped isoform of Synaptophysin OS=Gallus gallus OX=9031 GN=SYP PE=3 SV=1 CANONICAL=A0A8V0ZAK5-1" }, "locus": { "chromosome": "12", "start_pos": 13673186, "end_pos": 13598291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051130.1", "url": "https://www.ensembl.org/id/ENSGALT00010051130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030321.1", "url": "https://www.ensembl.org/id/ENSGALP00010030321.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK5" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 201, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAK7-1", "uniprot_ac": "A0A8V0ZAK7", "uniprot_id": "A0A8V0ZAK7_CHICK", "mass": { "chemical_mass": 10698.0, "monoisotopic_mass": 10698.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Alpha/beta hydrolase domain-containing protein 17C", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.22", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZAK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "19233", "url": "https://www.rhea-db.org/rhea/19233", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS", "length": 94, "header": "tr|A0A8V0ZAK7-1|A0A8V0ZAK7_CHICK Isoform 1 of Alpha/beta hydrolase domain-containing protein 17C OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZAK7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7/entry#A0A8V0ZAK7-1", "sequence": { "sequence": "MSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS", "length": 94, "header": "tr|A0A8V0ZAK7-1|A0A8V0ZAK7_CHICK Isoform 1 of Alpha/beta hydrolase domain-containing protein 17C OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZAK7-1" }, "locus": { "chromosome": "10", "start_pos": 12372516, "end_pos": 12368844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047737.1", "url": "https://www.ensembl.org/id/ENSGALT00010047737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028231.1", "url": "https://www.ensembl.org/id/ENSGALP00010028231.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of protein localization to endosome", "id": "GO:1905668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905668", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" }, { "name": "negative regulation of protein localization to microtubule", "id": "GO:1902817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19233", "name": "", "equation": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJX1-1", "Q5ZIV7-1", "Q5ZJ01-1", "F1NKJ7-1", "A0A8V0YR47-1", "A0A3Q3B0Z9-1", "F1P042-1", "A0A1D5P263-1", "A0A8V0YRM3-1", "A0A8V0Z1P7-1", "A0A8V0ZAK7-1" ], "evidence": [ { "id": "19233", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19233" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P263", "gene_name": "LYPLA1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A1D5P263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P263" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A1D5P263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P263" } ] } ] }, { "uniprot_ac": "A0A3Q3B0Z9", "gene_name": "DESI1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A3Q3B0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B0Z9" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A3Q3B0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B0Z9" } ] } ] }, { "uniprot_ac": "A0A8V0YR47", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] } ] }, { "uniprot_ac": "A0A8V0YRM3", "gene_name": "LYPLA2", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8V0YRM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM3" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8V0YRM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1P7", "gene_name": "LYPLAL1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8V0Z1P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8V0Z1P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1P7" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK7", "gene_name": "", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8V0ZAK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8V0ZAK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK7" } ] } ] }, { "uniprot_ac": "F1NKJ7", "gene_name": "ABHD10", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "F1NKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKJ7" } ] }, { "ec_number": "3.1.1.93", "activity": "mycophenolic acid O-acyl-beta-D-glucuronide + H2O = mycophenolate + D-glucuronate + H(+).", "evidence": [ { "id": "F1NKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKJ7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "F1NKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKJ7" } ] }, { "ec_number": "3.1.1.93", "activity": "", "evidence": [ { "id": "F1NKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKJ7" } ] } ] }, { "uniprot_ac": "F1P042", "gene_name": "SYNJ2BP", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "F1P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P042" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "F1P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P042" } ] } ] }, { "uniprot_ac": "Q5ZIV7", "gene_name": "DESI2", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "Q5ZIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIV7" } ] }, { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q5ZIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIV7" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q5ZIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIV7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "Q5ZIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIV7" } ] } ] }, { "uniprot_ac": "Q5ZJ01", "gene_name": "ABHD17B", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "Q5ZJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ01" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "Q5ZJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ01" } ] } ] }, { "uniprot_ac": "Q5ZJX1", "gene_name": "ABHD17C", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "Q5ZJX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJX1" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "Q5ZJX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJX1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.22", "ec_name": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "3.1.2.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22" }, { "id": "3.1.2.22", "database": "BRENDA Enzymes", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAK8-1", "uniprot_ac": "A0A8V0ZAK8", "uniprot_id": "A0A8V0ZAK8_CHICK", "mass": { "chemical_mass": 206924.0, "monoisotopic_mass": 206924.0 }, "refseq": { "ac": "XP_046798599", "name": "zinc finger protein 106 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798599" }, "gene_names": [ { "name": "ZNF106", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ] }, { "name": "ZNF106", "type": "synonym", "evidence": [ { "id": "XP_046798599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798599" } ] } ], "protein_names": [ { "name": "Zinc finger protein 106", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 474", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 106 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046798599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798599" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046798599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798599" } ] }, { "annotation": "RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8#function" }, { "database": "UniProtKB", "id": "ARBA00056374", "url": "https://www.uniprot.org/uniprotkb/ARBA00056374#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF106", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8", "locus": { "chromosome": "5", "start_pos": 25199602, "end_pos": 25232318, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019509", "url": "https://www.ensembl.org/id/ENSGALG00010019509" } ] } } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423234", "url": "https://www.ncbi.nlm.nih.gov/gene/423234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TNMFLCE", "url": "https://omabrowser.org/oma/group/TNMFLCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZAK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14435:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14435:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046798599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRERKCILCHIVYSSKKEMEEHMRSMLHHRELENLKGRDSNHECQVCRVTLVGLSAYAKHISSQLHKDNVDAHDKAEEKEEAEEEYLDKELIQLIKQRKERNRQVEQCCTNQETECDDRRSQRRREERATYKEREAYDQSSWHHHNVSQRDWKWERDDYINSRQGKFSHSQRNLNISRHPAGPRGRSGWHQNVSGSSSSWHNYGNSGIVWHPNGRGGGISNWHHSARGRNSTWHTEGTGNFSSWNCKSYGGNWKSNSHGANSWNFGSSGDAYLLEPAKYNKERYMWQWQEKDMTDVIPYRDRNNRSDSFDFTSDKLPSEGALDFGTSKQPESKAPRNSGKSGSPSRDKIYRWTPYPSQKSTEQQSWFEDVSKATEKMDSVYLPLTESSVKGKTCEATASLLKLKKWEASPPSNVTLDYPDSSDEKPDKDDGRSRRMPSLKSPLLNITDIKLSSQKQDTKSLLKNVKSLLSSPSSKEQNRLKALNLEADNMPSYSSELHGASAGNLQGSNKDTLSSNPGEPVNNLGEAEQKPKDVQSNHSLQNASLNSCKNTSDQNMEETGKASPKNKFRLHSLEDVSEDELTGTEKVEIRVEKLSPSVSSCLLCDTPEGKLAASEKDVDEKPSASSIASADLKDSMCQMESTVSPSNSQDHLQVGLKTSSQEGEVNEENVKSGGRFEVEGFENHSDHELQKGGSQSLGLLPDLSKLGLPASLQRDLTRHISLKSKVGIHLPEPNLNNARRIRNVSGHRRSETEKESGLKPTLRQILSASRRNVNWDQVIQQVSKKKQELGKGLPRFGIEMVPLVQNDQECLELGEESDLSTLEGFQWEGISLAVPGSARKRSFSESSVIADRHPSAYSFFSEQPKAKECEERQIVAARHLRDITSGYEASVDIEADSKQETSSLSLSPFISERTETTGRKHSLQAASELTGLTKAEQDSLDKRTPLLEKQNVLEISEENPLASSDVLLAVSNNIDAATDSSYTSGTEQNDSQGIGKKRRATGEGSSPEIPSLERKNKRRKIKGKKERSQVDQLLAISLREEELSKSLHSVDNSLLQARAALQAAYVEVQRFLVLKQQITMEMSALRSQRIQILQGLQETYEPSELSEQLPSSVSSERRSSKSQVSADLLPAGSFLPLLDTLSPVPPLGTSVHVNTSTPFHSGITFTTPPDSSVQIKREPVSLEASEENANTVLQSSLCASRTEVVAQKDEEIIQKTSVYPVISATISLSELTACFQHTNQEIHKPAVDRGKAGLSENPSPSLSTFSKREANGTVTESFLLDQCSTLLPNRSVLLEMPMDKTPKLSAEASEQQAANTLVPAEKGNRRRRKLRKKKTLRAAHVPENSDTEQDIIDCKPTRKVKSGKVPKGEKVTTSAHQKQGDGVAIQAARNKDENDSDASLELVEVATPQCEVVDIGSSESGDEKPDSPSKRELCSAVDQAVLEASCSGYDEVSSTSEIGTSYRDDMKRSVAETQASISSLRGSKNSSEVSSEPGEDEEPTEGSFEGHLAAVNAIQIFGNLLYTCSADKTVCAYNLVSRKCVAVFEGHTSKVNCLLVTQTNGKNAALYTGSSDHTINCYNIKTKECMEQFKLEDRVLCLHSRWRILYAGLANGSVVTFNIKNNKQVDTFECHSPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHSDMIMCMTIHKSMIYTGCYDGSVRAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDGFFTSRKGSKQDAVGHIERHAEDDSRVDS", "length": 1861, "header": "tr|A0A8V0ZAK8-1|A0A8V0ZAK8_CHICK Isoform 1 of Zinc finger protein 106 OS=Gallus gallus OX=9031 GN=ZNF106 PE=4 SV=1 CANONICAL=A0A8V0ZAK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8/entry#A0A8V0ZAK8-1", "sequence": { "sequence": "MVRERKCILCHIVYSSKKEMEEHMRSMLHHRELENLKGRDSNHECQVCRVTLVGLSAYAKHISSQLHKDNVDAHDKAEEKEEAEEEYLDKELIQLIKQRKERNRQVEQCCTNQETECDDRRSQRRREERATYKEREAYDQSSWHHHNVSQRDWKWERDDYINSRQGKFSHSQRNLNISRHPAGPRGRSGWHQNVSGSSSSWHNYGNSGIVWHPNGRGGGISNWHHSARGRNSTWHTEGTGNFSSWNCKSYGGNWKSNSHGANSWNFGSSGDAYLLEPAKYNKERYMWQWQEKDMTDVIPYRDRNNRSDSFDFTSDKLPSEGALDFGTSKQPESKAPRNSGKSGSPSRDKIYRWTPYPSQKSTEQQSWFEDVSKATEKMDSVYLPLTESSVKGKTCEATASLLKLKKWEASPPSNVTLDYPDSSDEKPDKDDGRSRRMPSLKSPLLNITDIKLSSQKQDTKSLLKNVKSLLSSPSSKEQNRLKALNLEADNMPSYSSELHGASAGNLQGSNKDTLSSNPGEPVNNLGEAEQKPKDVQSNHSLQNASLNSCKNTSDQNMEETGKASPKNKFRLHSLEDVSEDELTGTEKVEIRVEKLSPSVSSCLLCDTPEGKLAASEKDVDEKPSASSIASADLKDSMCQMESTVSPSNSQDHLQVGLKTSSQEGEVNEENVKSGGRFEVEGFENHSDHELQKGGSQSLGLLPDLSKLGLPASLQRDLTRHISLKSKVGIHLPEPNLNNARRIRNVSGHRRSETEKESGLKPTLRQILSASRRNVNWDQVIQQVSKKKQELGKGLPRFGIEMVPLVQNDQECLELGEESDLSTLEGFQWEGISLAVPGSARKRSFSESSVIADRHPSAYSFFSEQPKAKECEERQIVAARHLRDITSGYEASVDIEADSKQETSSLSLSPFISERTETTGRKHSLQAASELTGLTKAEQDSLDKRTPLLEKQNVLEISEENPLASSDVLLAVSNNIDAATDSSYTSGTEQNDSQGIGKKRRATGEGSSPEIPSLERKNKRRKIKGKKERSQVDQLLAISLREEELSKSLHSVDNSLLQARAALQAAYVEVQRFLVLKQQITMEMSALRSQRIQILQGLQETYEPSELSEQLPSSVSSERRSSKSQVSADLLPAGSFLPLLDTLSPVPPLGTSVHVNTSTPFHSGITFTTPPDSSVQIKREPVSLEASEENANTVLQSSLCASRTEVVAQKDEEIIQKTSVYPVISATISLSELTACFQHTNQEIHKPAVDRGKAGLSENPSPSLSTFSKREANGTVTESFLLDQCSTLLPNRSVLLEMPMDKTPKLSAEASEQQAANTLVPAEKGNRRRRKLRKKKTLRAAHVPENSDTEQDIIDCKPTRKVKSGKVPKGEKVTTSAHQKQGDGVAIQAARNKDENDSDASLELVEVATPQCEVVDIGSSESGDEKPDSPSKRELCSAVDQAVLEASCSGYDEVSSTSEIGTSYRDDMKRSVAETQASISSLRGSKNSSEVSSEPGEDEEPTEGSFEGHLAAVNAIQIFGNLLYTCSADKTVCAYNLVSRKCVAVFEGHTSKVNCLLVTQTNGKNAALYTGSSDHTINCYNIKTKECMEQFKLEDRVLCLHSRWRILYAGLANGSVVTFNIKNNKQVDTFECHSPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHSDMIMCMTIHKSMIYTGCYDGSVRAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDGFFTSRKGSKQDAVGHIERHAEDDSRVDS", "length": 1861, "header": "tr|A0A8V0ZAK8-1|A0A8V0ZAK8_CHICK Isoform 1 of Zinc finger protein 106 OS=Gallus gallus OX=9031 GN=ZNF106 PE=4 SV=1 CANONICAL=A0A8V0ZAK8-1" }, "locus": { "chromosome": "5", "start_pos": 25224962, "end_pos": 25200055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047111.1", "url": "https://www.ensembl.org/id/ENSGALT00010047111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027956.1", "url": "https://www.ensembl.org/id/ENSGALP00010027956.1" } ] } }, { "isoform_ac": "A0A8V0ZHA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8/entry#A0A8V0ZHA8-1", "sequence": { "sequence": "MPVGRTKSPPSASLPRDSNHECQVCRVTLVGLSAYAKHISSQLHKDNVDAHDKAEEKEEAEEEYLDKELIQLIKQRKERNRQVEQCCTNQETECDDRRSQRRREERATYKEREAYDQSSWHHHNVSQRDWKWERDDYINSRQGKFSHSQRNLNISRHPAGPRGRSGWHQNVSGSSSSWHNYGNSGIVWHPNGRGGGISNWHHSARGRNSTWHTEGTGNFSSWNCKSYGGNWKSNSHGANSWNFGSSGDAYLLEPAKYNKERYMWQWQEKDMTDVIPYRDRNNRSDSFDFTSDKLPSEGALDFGTSKQPESKAPRNSGKSGSPSRDKIYRWTPYPSQKSTEQQSWFEDVSKATEKMDSVYLPLTESSVKGKTCEATASLLKLKKWEASPPSNVTLDYPDSSDEKPDKDDGRSRRMPSLKSPLLNITDIKLSSQKQDTKSLLKNVKSLLSSPSSKEQNRLKALNLEADNMPSYSSELHGASAGNLQGSNKDTLSSNPGEPVNNLGEAEQKPKDVQSNHSLQNASLNSCKNTSDQNMEETGKASPKNKFRLHSLEDVSEDELTGTEKVEIRVEKLSPSVSSCLLCDTPEGKLAASEKDVDEKPSASSIASADLKDSMCQMESTVSPSNSQDHLQVGLKTSSQEGEVNEENVKSGGRFEVEGFENHSDHELQKGGSQSLGLLPDLSKLGLPASLQRDLTRHISLKSKVGIHLPEPNLNNARRIRNVSGHRRSETEKESGLKPTLRQILSASRRNVNWDQVIQQVSKKKQELGKGLPRFGIEMVPLVQNDQECLELGEESDLSTLEGFQWEGISLAVPGSARKRSFSESSVIADRHPSAYSFFSEQPKAKECEERQIVAARHLRDITSGYEASVDIEADSKQETSSLSLSPFISERTETTGRKHSLQAASELTGLTKAEQDSLDKRTPLLEKQNVLEISEENPLASSDVLLAVSNNIDAATDSSYTSGTEQNDSQGIGKKRRATGEGSSPEIPSLERKNKRRKIKGKKERSQVDQLLAISLREEELSKSLHSVDNSLLQARAALQAAYVEVQRFLVLKQQITMEMSALRSQRIQILQGLQETYEPSELSEQLPSSVSSERRSSKSQVSADLLPAGSFLPLLDTLSPVPPLGTSVHVNTSTPFHSGITFTTPPDSSVQIKREPVSLEASEENANTVLQSSLCASRTEVVAQKDEEIIQKTSVYPVISATISLSELTACFQHTNQEIHKPAVDRGKLRKKKTLRAAHVPENSDTEQDIIDCKPTRKVKSGKVPKGEKVTTSAHQKQGDGVAIQAARNKDENDSDASLELVEVATPQCEVVDIGSSESGDEKPDSPSKRELCSAVDQAVLEASCSGYDEVSSTSEIGTSYRDDMKRSVAETQASISSLRGSKNSSEVSSEPGEDEEPTEGSFEGHLAAVNAIQIFGNLLYTCSADKTVCAYNLVSRKCVAVFEGHTSKVNCLLVTQTNGKNAALYTGSSDHTINCYNIKTKECMEQFKLEDRVLCLHSRWRILYAGLANGSVVTFNIKNNKQVDTFECHSPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHSDMIMCMTIHKSMIYTGCYDGSVRAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDGFFTSRKGSKQDAVGHIERHAEDDSRVDS", "length": 1760, "header": "tr|A0A8V0ZHA8-1|A0A8V0ZHA8_CHICK Computationally mapped isoform of Zinc finger protein 106 OS=Gallus gallus OX=9031 GN=ZNF106 PE=4 SV=1 CANONICAL=A0A8V0ZAK8-1" }, "locus": { "chromosome": "5", "start_pos": 25219216, "end_pos": 25200055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047102.1", "url": "https://www.ensembl.org/id/ENSGALT00010047102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027953.1", "url": "https://www.ensembl.org/id/ENSGALP00010027953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHA8-1", "protein_name": "Zinc finger protein 106", "gene_name": "Dmel\\CG14322", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAPQQQRGESGGGAPPDTGRDSASQPAKSSTASGSGHSATCSHSPSSKNRRQNNSMKYNSRPWQRGRSDSGHFNNRVHSNHNQRQTPYPKSNYENRGRSDTRSSNQERQERDYTKRTDFRERNTRFSDERHSGRYSDYHRRNHYHRFKSWGSEGRSYRRDKGARDLSKSRYDNDASGSSLIRGASEIRRKNGHNCDPNSDASKTENSEDIQSCINHYQTEENKIDTEQSKDQGANRTSPTEQLSDISKQSNPIALEGDQNKKTNELKESSCSSKPSREINETSKASQFPDQRSKEQSSGEELNVSESSDNHSGAQASQSIPRIQVRPLTKLLRQELFAVTQENRLIKSPPPSASPASPSRLVFTPNLRNRRRTVSNCIYNAGSFDQTAESEAVFNDRIASMDKESLKYIINNGDTIFEPHLQLQARRRIRDEIRRQLKTIELEKPKDCLVTDLVEDEIVDSIKLPAFLLEEIGKCFGIDISEGQTTKDSAAEREDTTRVNAESPVQDTEEETKRACNGVESLKDIKTEATADDSNQCTKFRNLENEIDINDNHHQSEDDELSKPLSVLPKDSEDCSVKSNGVSKKVLQENNKKKTFNRDTKVNGNKAMNPPQETVIETLEHSDSINRSITNPKTADELKSFAGIEWEVNSKSKHSNPSQSAFIKTNKSNNIETALIDSLSGISKPCKMEIKRESSSSPISVSSLPSNDVIDLLSSSDEELEEHAVVDMDIDEHEGDIENQKIFKTLEALKQSDDVVDSDDSTSSQSSSKSTKRRRRLKLQNDAENVVDSFEKLILPHLREALSDRYRRQHSSSLQSRLHFISCVVTSSEHNAQTFSKIEVAKMQMNLKAADNRQAIEFLLKEIVNVVSLQKQRRREQDEEQKLANLLSPKKTAFTSDETCKASTLCPNQHGFIPPTAQDSSPVTSPCQKPPSSPPSQQSPSSATAQQSSPMALQKTQSCPARQSSTSIQENPMDSSGQWRGSASHKTQSSPARQTTPVGDVFENPSPNQGNPPSSAKLESFNVGFPFLSMDPTLYNYSRLASGSKINEPLGKSDDMMEQHLVEIERELIKHENRYSFLDDIIIKFQKEKSEVGMVILELKSRKFLIINSMASRNQATSAQVADSKSKPHEAETAQESTHEDSFSKGGIARRTRSRLRRTVLVLAPKRQVRVQKRVSKKPKSFKLVEKSHEEIAEQETNKMDSKATNQLNINEELLKVSAGDQVSDYSPTAKLAQSRLSKPSIAVNPTHQPLAIIPPLPPPPPPPEPICHMSYEASSSFLKEPLHEPGHQLSELNSEDKTRQGFVTKGKLQNVGSPITQIKIYRDNVIAAAEDGDIYVFHLVTHKLEQKITKHSEAITNMFLSEKDSILYTTSADGFFKKSSLLNLERVFETVYLKEPLQSMDVAWGLAFIGSRWGQISTFNVVTNKVVEKPLVSTGQSIIAIKATKEGVRKILVLGCKGNFVQMHDAGNGLLLRHVFIAEGLNIYSLLLDEGHIYCGTQKNELYQLEFVSGNLVTKFSCGNGAVAVAAYGERYLLVGCYDGYIYVLNKITGTQTGRFAGAGRMVLALSVVGDKIVTSSKDNSLAILEVPPALVNGY", "length": 1597 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0G2K2F8-1", "protein_name": "Zinc finger protein 106", "gene_name": "Zfp106", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRERKCILCHIVYGSKKEMDEHMRSMLHHRELENLKGRDISHECRVCRVTEVGLSAYAKHISGQSHKDNVDAQEREDDGKEEEEEDYFDKELVQLIQERKEQSRQDKPSGNNQEGNSDDRQPQWRREDRIPYQDRESYNQPARHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNSGGPRGSSGWHKGATRGSSTWFHSHSNSGGGWHSNNGMVDWNYNGTGRNPGWHPEGTGGFPNWHMNNSNGNWKSNVRGTNSWNYKGPGDKFQQGRNRNSNYQMEDVTKMWSKKSNKPSKYSQERCKWPRQDRDKAGKYRSPQEGYTSDTFPSEGLLEFNFEQRESQTTKQTDTAVSKINGKNGTKAREKFRRWTPYPSQRTLDLQSALKEVIGNKSETIDKPLFNFSLITAGLKEPVDKTSNPPVLKTQKEVDLGSSNHKAVSDGAALCEVARACPITEQSEPHQKSNKIPLLKSPLLPLPTPKSGPHKHNLKNRSKTNETKSFPSGDHSHLLNKSTLEGSHGSSYTSKSHGLCPRVLKGNKTASDTQKEPDEKLNSTSQKAQEVLQCPKTLQHPLLGTPKRVENHAKESSVEESTRDSVDIEFQAHSAENSGAISEPESHGIESKDVASLTTEVASCSAHTGDKEQGSQILGTPENLSASPHNSTVHQKEAELQVTAATSPHSGLLLDLKTSLEDAQDHNLVKSDGLFETESFEGTSLDAELQKTDINNQPPGTLLPELSKLGFPASLQRDLSRHISLKTKTGTHLPEPNLNSARRIRNISGHRKNETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVHNEQEVLDLEEEPDLSSLEGFQWEGVSISSSSGLARKRSLSESSVVLDRAPVYGFFTGEGAGKEKEAQQSPSPSTASQKAAMYLEPEVAPLSPSVRTGERVGTGPTQRRHSAQLPSDHIMPFMHSARDLHSQERTTPLSEHHTQESTGEGNPLSSTASSSGHAVSSLADAATDSSCTSGTEQNDGHSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLTISLREEELSKSLQCMDNKLLQARAALQTAYVEVQRLLMLKQQVTVEMSALRTHRIQILQGLQETYEPSEHPDQTPCSLIAREHRDSRSQPSVETALLPVPFFPGFLDPPPSHASLPSSGTPLQITTCTFQAHGTAPDSSIQIKQEPMSPEQEGNMNTVPQGSASNVSKELLQTNRVAGDSCPVYPAIPAVITSESTENCQEVNQDLNFSVEQGNSRSRENSPPCQSPDPPGVNKGEGSAKGSSGSEACSSSSLRLSFTPETPAEKETQSPADQPEQQAESTLTSAETRGSKKKKKLRKKKTLRATHVPENSDTEQDVFTTKPARKVKTGKAAKGGKVTTSTWGDSQTGREQETARDEPDSESSLEVLEVPNPQLEVVAIESSESGEEKPDSPSKKDTWTAVEQNSIEPSRSGCDEVSSTSELGTRYRDGVPVSVAETQTVISSIKASKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNSLYTCSADTTVRVYNLVSRKCVGVFEGHISKVNCLLVTHTSGKNSVLYTGSSDHTIRCYNVKTRECMEQLQLEDRVLCLHNRWRTLYAGLANGTVVTFNIKNNKRQEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSVIYTGCYDGSIQAVRLNLMQNYRCWWHGCTLIFGVVDHLKQHLLTDHTNPNFQTLKCRWRNCDAFFTARKGSKQDVAGHIECHAEDDSKIDS", "length": 1889 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9U073-1", "protein_name": "Zinc finger protein 106", "gene_name": "ZNF106", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRERKCILCHIVYSSKKEMDEHMRSMLHHRELENLKGRDSSHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKEEEEEDYFDKELIQLIKQRKEQSRKDEPSNSSQEINSDDRRPQWRREDRIPYQDRESYSQPAWHHRGPPQWDRKWEKDGYSNTRKNSFTHSSRNNGGSRGCSGWHNGGAGGPSPWFHNHSNSGGGWHSNSGTVDWNHNGTGRNSSWHSEGAGGFSSWHMNSSNGNWKSSARGTNSWNYSGPGDKFQPGRNRNSNCQMEDMNMLWNTKSKSNKYNQDRYKWQWQENDKVGAVATYRGPSEGFASGKFHSEGLLDFNFEQLESQTTKQTDTFTSKIGGKSGSVAREKLHRWTPYPSQKTLDLQSGMKEVTGNKSEMIDKPLFDFSLITTGIKEPPNDKTNNSQKLKTKKEKHIESLKHKASSDCTASYEVVRECPITEKPEQEPNLNKMPSLKSPFLPTPGSKSVPQKQDSKNPSKNTKINSFFSGEHSNPLAKHTVEDNQSSCISKMRSSGPHVLKGNNKSSLGTQRDSDENLSDTLQKAKDVLQCHETLQNPLSTSKRTRNYAKASRNVEESEKGSLKIEFQVQTLEDESDGEISDTEKHETKIETLGSTTTEVLSCSTPAADEKRGDDQNLETSRKPSTSPCNSAVHQKETELQMTSVASPQSGLLLDLKTSLEDAQVDDPVKSHESYETEGFESTSLDAELQKSDIGQPSGPLLPELSKLGFPASLQRDLTRHISLKSKTGAHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEVLDLDGEPDLSDLEGFQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQIFSPNNSFRSAQSQKPTMSLKQEVTPLAASLRTDERTENVAARRRHSAQLSPDRTIPLMHLTKELHSQESSTLLSENHNAQESNGEGNSLSSNASSALANSSLADAATDSSCTSGAEQNDGQNVRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAALQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPSSLTREQKNVRSQTSTDVTLLPSPFFPNFLEPPSSHVSPSPAGTPLQAITSSFQAHGSVPAPDSSVQIKQEPMSPEQEETVNAISQGSACSVSKELLQANREISDSCPVYPVTTAALSLSGLTERFHEPSQELKFSVEQGITRNRGNNPSSQSAGLPSIDKESEEPNKGNSGSEACTSSFPRLSFASETPLEKEPHSPADQPEQQAESTLTSAEARGNKKKKKLRKKKTLRAAHVPENSDTEQDVFTAKPVRKVKTGKSAKGGKVTTSTWEDSRTGPEQESVRDEPDSDSSLEVLELPNPQLEVVAIDSSESGEEKPDSPSKKDIWNSTEQNSLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRAYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKTRHCVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTAKKGSKQDAAGHIEHHAEDDSKIDS", "length": 1903 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H0X4-1", "protein_name": "Zinc finger protein 106", "gene_name": "Znf106", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRERKCILCHIVYGSKKEMDEHMRSMLHHRELENLKGRDSSHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDGGKEEEEEDYFDKELVQLIQERKEQSRQDEPSSNSQEINSDDRQPQWRREDRIPYQDRESYNQPARHHRGPPPRDWKWEKDGFNNTRKSSFPHSLRNSGGPRGSSGWHKGATRGSSAWFHSHSNSGGGWHSNSGMVDWNYNSTGRNSSWHSEGTGGFSSWHMNNSNGNWKSSVRGTNSWNYNGPGDKFQQGRNRNSNYQMEDMTKMWNKKSSKPSKYNQERYKWQWQDSDKAGKYRSSSEGFASDKFPSEGLLEFSFEQRESQTTKQTDSASKVNGKNGNVAREKFRRWTPYPSQKTPDLQSALKEVTSNKSEMTDKPLFNFSLITAGMQEPIDKTSNPPVLKTQKEILPGSPKAVPDGTAFCEVVRACPITELSEPHRKSNKIPLLKSPLLPLPTPKSGPHKHNLKNRSKNNETKSFSSGDHSHFLKKSTSEGSHGSPYTSKLHGLCPRVLKGTKTLSGTEKEPDEKLNDTSQKVQEVLQCSRTPQKPLLSTSKRPESHAKESRSVQESTQDSVNTEFQAHSAENDGTTSDPENHGIKSGAVALATTEAVSCGTHTVGKEQGNQILGTSGTLSTSPHNSTVHQKEAELQVTAAAGPHSGLLLDLKSSLEDVQNNGLAKPDAPFETESFEDTSLDAELQKSDINNQPPGTLLPELSKLGFPASLQRDLTRHISLKSKTGAHLPEPNLNSARRIRNISGHRKNETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEVLDLDEEPDLSRLEGFQWEGVSISTSPGLARKRSLSESSVIVDRAPVYSLFSEEGTGKENKPQPSNSPAAAQSQKTAMYLEQEVAPLTPSARSGERVGNIPTPRRHSTQLPSDHTMPFMHSARDLHSQERSTLSLERHAQESNGEGNSLSSNASSVHALSSLADAATDSSCTSGAEQNDGHSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDSNLLQARAALQTAYVEVQRLLMLKQQISMEMSALRTHRIQILQGLQETYEPSEHPDQAPCSLIAREQRNSRSQTSVETTLLPAPFFPGFLEPPPSLVSPSSIGTPLQITTSAFQVHGTVPDSSVQIKQEPMSPEQEGNMNAVPQGSAANVSKELLQTNRVASDSLPVNPALPAALTSGSTESCQEANQDQNCSVEQGSSRSRENSPSSQPCDLPGMNKGEESARGSSGSEACSSSFLRLSFTPETPVEKETHSPPEPQAESTLASAESRGSKKKKKLRKKKTLRATHVPENSDTEQDVFTAKPARKVKSGKVAKGGRVTTSTWEDSRTGREHEPVRDEPDSESSLEVLEVPNPQLEVVAIDSSESGEEKPDSPSKKDSWSSAEQNPAEVSRSGCDEVSSTSELGNRYKDGIPVSVAETQTVISSIKASKNSSELSSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADTTVRVYNLVSRKCIGVFEGHTSKVNCLLVTHTSGKNSVLYTGSSDHTIRCYSAKTRECMEQLKLEDRVLCLHNRWRILYAGLANGTVVTFNIKNNKQQEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSVIYTGCYDGSIQAVRLNLMQNYRCWWHGCTLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTARKGSKQDVAGHVERHAEDDSKMDS", "length": 1884 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88466-1", "protein_name": "Zinc finger protein 106", "gene_name": "Znf106", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRERKCILCHIVYGSKKEMDEHMRSMLHHRELENLKGRDISHECRVCRVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKEEEEEEYFDKELVQLIQERKEQSRQDEPPSNSQEVNSDDRQPQWRREDRIPYQDRESYSQPPRHHRGPPQRDWKWEKDGFNSTRKNSFPHSLRNSGGPRGSSVWHKGATRGSSTWFLNHSNSGGGWHSNNGMVDWNYNGTGRNSSWHSEGTGGFPSWHMNNSNGNWKSSVRGTNSWNYNGLGDKFQQGRNRNPNYQMEDMTKMWNKKSNKPSKYSQERCKWQRQDRDKAAKYRSPPEGYASDTFPSEGLLEFNFEQRESQTTKQTDTAASKINGKNGTKARDKFRRWTPYPSQKTLDLQSALKEVIGSKSDTLEKPLFNFSLITAGLRKPVDKTSNPPVIKTQKAGPPGSPSHKAISDGTAFCEVARACSITEQSEPHQKSNKIPLLKSPLLPLPTPKSGPHKQNLKNRSKNKETKSFPSGDHSHLLNTSTLEGSHGSSYTSKSLGLCPRVLKENKTVSGTQKEPDEKLNNTSQKAQDTVLQCPKTLQNPLPTTPKRMENDAKESSVEESAKDSLSIESQPHSAGNSAMTSDAENHGIKSEGVASLTTEVVSCSTHTVDKEQGSQIPGTPENLSTSPRNSTVLQKEAEVQVSAATSPHSGLLLDLKTSLEDAQDNNLVKSDGPFETESFEDTSLDTELQKPDLNNQPPGTLLPELSKLGFPASLQRDLSRHISLKSKTGTHLPEPNLNSARRIRNVSGHRKNETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEVLDLDEEPDLSSLEGFQWEGVSIPSSSGLARKRSLSESSVVMDRAPVYSFFTGEGTGKENEAQQSPSPNTALSAAQSQKTAMYLEQEVAPLTPSVGTGERVGNIPTQRRHSAQLPSGHIMPVMHSARDLHSQERSTPLSERHAQESTGEGNSLSSNASSGHAVSSLADAATDSSCTSGAEQTDGHSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLTISLREEELSKSLQCMDNKLLQARAALQTAYVEVQRLLVLKQQITVEMSALRTHRIQILQGLQETYEPPEHPDQAPCSLISREQRNSRSQTSFETALLPAPFFPGFLDPPPSHASLPSPGNPLQITMSTFQAHGTAPDSSVQIKQEPMSPEQEGNMNALPQGCASNVSKELLQTNRVVDDGSSVYPAIPAVIASESTENCQEVSKDLNFSVEQGNSRSKGNSPSCQSPDLPGINRGEETAKGSSGSEACSSSFLRLSFTPETPAEKETQSPADQPEQQAESTLASAETRGSKKKKKLRKKKTLRATHVPENSDTEQDVFTAKPARKVKTAKAAKGAKVTTSQTGQEQGTARDEPDSDSSLEVLEVTNPQLEVVAIDTSESGDEKPDSPSKKDAWIAAEQNPIETSRSGCDEVSSTSELGTRYKDGVPVSVAETQTVISIKASKHSSEISSEPGDDEEPTEGSFEGHQAAVNAIQIFGNFLYTCSADTTVRVYNLVSRKCVGVFEGHTSKVNCLLVTHTSGKSSVLYTGSSDHTIRCYNIKTRECMEQLQLEDRVLCLHNRWRTLYAGLANGTVVTFDIKNNKRQEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSVIYTGCYDGSIQAVRLNLMQNYRCWWYGCTLIFGVVDHLKQHLLTDHTNPNFQTLKCRWRNCDAFFTARKGSKQDVAGHIERHAEDDSKIDS", "length": 1888 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2Y7-1", "protein_name": "Zinc finger protein 106", "gene_name": "ZNF106", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVGRIECPSSPSFPRDISHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKGEEEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQWRREDRIPYQDRESYSQPAWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGRSGWHKGVAGGSSTWFHNHSNSGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHMNNSNGNWKSSVRSTNNWNYSGPGDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHDRYNWQRQENDKLGTVATYRGPSEGFTSDKFPSEGLLDFNFEQLESQTTKQADTATSKVSGKNGSAAREKPRRWTPYPSQKTLDLQSGLKDITGNKSEMIEKPLFDFSLITTGIQEPQTDETRNSPTQKTQKEIHTGSLNHKASSDSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPATKSLSQKQDPKNISKNTKTNFFSPGEHSNPSNKPTVEDNHGPYISKLRSSCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKEVLQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQVHALEDESDGETSDTEKHGTKIGTLGSATTELLSGSTRTADEKEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAASPHPGLLLDLKTSLEDAQVDDSIKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELSKLGFPASLQRDLTRHISLKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEGFQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRAGQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQERSIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAALQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERRNSRSQTSIDAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIKQEPMSPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEPSQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASETPLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVKPVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVVAIDSSESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTARKGSKQDAAGHIERHAEDDSKIDS", "length": 1883 }, "evidence": [ { "id": "A0A8V0ZAK8", "url": "https://omabrowser.org/oma/group/A0A8V0ZAK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1290, "end_pos": 1292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1395, "end_pos": 1397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1486, "end_pos": 1488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1612, "end_pos": 1614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK8" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 29, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 1272, "end_pos": 1274 }, { "start_pos": 1290, "end_pos": 1292 }, { "start_pos": 1395, "end_pos": 1397 }, { "start_pos": 147, "end_pos": 149 }, { "start_pos": 1486, "end_pos": 1488 }, { "start_pos": 1612, "end_pos": 1614 }, { 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11681717, "end_pos": 11678072, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019246", "url": "https://www.ensembl.org/id/ENSGALG00010019246" } ] } } ], "crossref": [ { "id": "A0A8V0ZAM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAM0", "url": "https://www.orthodb.org/?gene=A0A8V0ZAM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZAM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"sequence": { "sequence": "MRCPGPTGRAPGLLLLLLLLLAAGGRGAPGDAVICSQGLACRLLDSDVLCGTEPAAPGPGLTLLGLRLEPEVRCVGPDRCSPCLQARLRLGLEPEEGGGDAGTAASPRRDVTALLLLSGHGYASSRCVAVEVRASSAMPGRRLGSVRFCCFEAPLGSELHVTAYSGARGRRRLSQTQRLPDCSWPAARAAIPQCQVPRLQVSPGLTAVLVEVRVATVELNYTLRLYHNHSHGTGGSGRAVTASGPMNYSVPLEEVLPCLCLQVWPEIQDPLRATLCPFSHDVAAWERLWLQTQLVLHDVGQTFTCSISAPCDLPAELVPCWSPAPTAPCQALPSLRQPVTGQGPQEFQALQPHPNLCVQVRSSGRVRLTQCLRDREHPAVLPGRADDVLLMEPGGNASLCALQRGSCTPLSSFTAVQGAGRPGLLEQQLQEDVASGQCMQLWRPENGSGVTLWACPMHKYIRARWALAWLGALVCAACILLLLLLKKEDVKGWLKSLRAGCGSKAPLRGRRALLLHAAEPVAERAACVLAAALRPMGMAVVAAPGGGSGVAAWGPLPWLHALHRRALRDGDTIVLLLSPAAEAAARRWEDAAGDVSRAGDASSGPSPLHDPGSEVEPCEAFAAALSCAIPVLSAGAGRYVVARLEPTVTSVPQVLRAAPAFVLPSEAVGFLQALAGRRGCRLEPHAAAVAERLRRALGE", "length": 699, "header": "tr|A0A8V0ZAM0-1|A0A8V0ZAM0_CHICK Isoform 1 of Interleukin 17 receptor C OS=Gallus gallus OX=9031 GN=IL17RC PE=4 SV=1 CANONICAL=A0A8V0ZAM0-1" }, "locus": { "chromosome": "12", "start_pos": 11681699, "end_pos": 11678299, "strand": "-", "evidence": 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"header": "tr|A0A8V0ZAQ2-1|A0A8V0ZAQ2_CHICK Isoform 1 of Extracellular leucine rich repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ELFN1 PE=4 SV=1 CANONICAL=A0A8V0ZAQ2-1" }, "locus": { "chromosome": "14", "start_pos": 2745702, "end_pos": 2743300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047818.1", "url": "https://www.ensembl.org/id/ENSGALT00010047818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028267.1", "url": "https://www.ensembl.org/id/ENSGALP00010028267.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 405, "start_aa": "Thr", "end_pos": 405, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr405", 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAW7-1", "uniprot_ac": "A0A8V0ZAW7", "uniprot_id": "A0A8V0ZAW7_CHICK", "mass": { "chemical_mass": 190877.0, "monoisotopic_mass": 190877.0 }, "refseq": { "ac": "XP_040507379", "name": "eukaryotic translation initiation factor 4 gamma 3 isoform X20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507379" }, "gene_names": [ { "name": "EIF4G3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ] }, { "name": "EIF4G3", "type": "synonym", "evidence": [ { "id": "XP_040507379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507379" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4 gamma 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic translation initiation factor 4 gamma 3 isoform X20", "type": "synonym", "evidence": [ { "id": "XP_040507379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507379" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507379" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF4G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7", "locus": { "chromosome": "21", "start_pos": 6700290, "end_pos": 6605513, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021145", "url": "https://www.ensembl.org/id/ENSGALG00010021145" } ] } } ], "crossref": [ { "id": "cd11559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425544", "url": "https://www.ncbi.nlm.nih.gov/gene/425544", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAV7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZAW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGK1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZHZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040507379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPQKAALKPGAAAAAAGPGPGSGATAAAAAGPPPPPAPPHPAAAPAPHPAIRALPPAAPQQIPRGPVQQPLEERIFTPTVSAVYSTFISTQVTQVARQPGPPAPSPYTAHEINKGHPNIAATPPGHTSSPGLSQAPYPSGQNAAPTTLVYPQAPQTMNTQPQTRSPFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1751, "header": "tr|A0A8V0ZAW7-1|A0A8V0ZAW7_CHICK Isoform 1 of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZAV7-1", "sequence": { "sequence": "MNTQPQTRSPFAAGPRPAHHQFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSACKVQSGPGLPSLARCGSPACPLLVSPHPPLRNLPIGLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1641, "header": "tr|A0A8V0ZAV7-1|A0A8V0ZAW7_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6643250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051212.1", "url": "https://www.ensembl.org/id/ENSGALT00010051212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030403.1", "url": "https://www.ensembl.org/id/ENSGALP00010030403.1" } ] } }, { "isoform_ac": "A0A8V0ZAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZAW7-1", "sequence": { "sequence": "MSLPQKAALKPGAAAAAAGPGPGSGATAAAAAGPPPPPAPPHPAAAPAPHPAIRALPPAAPQQIPRGPVQQPLEERIFTPTVSAVYSTFISTQVTQVARQPGPPAPSPYTAHEINKGHPNIAATPPGHTSSPGLSQAPYPSGQNAAPTTLVYPQAPQTMNTQPQTRSPFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1751, "header": "tr|A0A8V0ZAW7-1|A0A8V0ZAW7_CHICK Isoform 1 of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6605712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051222.1", "url": "https://www.ensembl.org/id/ENSGALT00010051222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030413.1", "url": "https://www.ensembl.org/id/ENSGALP00010030413.1" } ] } }, { "isoform_ac": "A0A8V0ZGK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZGK1-1", "sequence": { "sequence": "MNTQPQTRSPGGFRPIQFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1600, "header": "tr|A0A8V0ZGK1-1|A0A8V0ZGK1_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6643250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051214.1", "url": "https://www.ensembl.org/id/ENSGALT00010051214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030405.1", "url": "https://www.ensembl.org/id/ENSGALP00010030405.1" } ] } }, { "isoform_ac": "A0A8V0ZGK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZGK6-1", "sequence": { "sequence": "MNTQPQTRSPPGRTVPIHCTDNWKRRKVLEQSPVYRSLAGRGWIKYCIFAAGPRPAHHQFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1642, "header": "tr|A0A8V0ZGK6-1|A0A8V0ZGK6_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6643250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051219.1", "url": "https://www.ensembl.org/id/ENSGALT00010051219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030410.1", "url": "https://www.ensembl.org/id/ENSGALP00010030410.1" } ] } }, { "isoform_ac": "A0A8V0ZHX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZHX7-1", "sequence": { "sequence": "MEEHFNLAVEGRVTRWDGLGTAACCCELVVTAVLGEAPYPSGQNAAPTTLVYPQAPQTMNTQPQTRSPFAAGPRPAHHQFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1662, "header": "tr|A0A8V0ZHX7-1|A0A8V0ZHX7_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6629633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051206.1", "url": "https://www.ensembl.org/id/ENSGALT00010051206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030397.1", "url": "https://www.ensembl.org/id/ENSGALP00010030397.1" } ] } }, { "isoform_ac": "A0A8V0ZHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7/entry#A0A8V0ZHZ1-1", "sequence": { "sequence": "MNTQPQTRSPPGRTVPIHCTDNWKRRKVLEQSPVYRSLAGRGWIKYCIFAAGPRPAHHQGGFRPIQFFQRPQIQPPRATIQNSSPSIRPGAQTPTAVYQTNQHIMMVNHLPMPYPMPQAPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGEFPNAYGTPFYPSQPVYQSAPIIVPTQQQQLPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIVRPTSTPTPPQQLPSQVPEPSPALYGPAESTHLTASAPGPVAIAPKQEEKPKPDPVLKLSSSVLRAESAAEKQDPAMPVAEPTPPHTPPAPAAAPSPPPAPLTAAATIAPAKPSPTADLEEGCEVASPKEEAMPLPSAVPCLDMLDPVPTEEPCGEACQEPGSAAAPADVPVTVSMNTINDLNGVSENVAAAESGAGVAAEDAVPLTDGPQEPGAAPGDLGTAPPPSTPHAAAAPSPLPAPAPSPPPPPPAAALTSTAPSPPSPLPPSAPPAQGDVEGEEGTRTAPSEELTDTEKKEETEADGQLEESTEALSLSSSKSPVPASTAVTAPKTWTKPKERTQGTEEVAEAEAEPKVEEELSSDKVLESEQDNMSHGFQLERDPSELKKVKPVEENGEQEAEPVRNGAESMSEGEGTDATSGCTEGSAEGPPLQYKPEQWKPLDPDGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKVRGEPIKQVNQPKLPLRTLDPRILPRGPDFTPAFADFGRQPSGGRNVPGSLLNVGPRRSQPGQRREPRKIITVCVKEDVHLKKAENAWKPSLKRENQTEDPENVKTQELFRKVRSILNKLTPQMFNQLMKQVTDLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGSTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAATTTEEKTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGTKNSRVLDPTKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASEMDSLRPSATSLNRFSALQPPVSSVSASSASSELDSRRALTSRGSTGREKNDKPLPPSLSRPNTFLRGSSSKELLLDNQAQEEQRREMLETVKQLTGGMEMDRNSTEAERSKAKESAKPEAPPAPVQEKPLLSEEEIERKCKSIIDEFLHINDFKEAMQCVEELSAQSLLPVFVRVGVESTLERSQITRDHMGQLLHQLVQSGKLSKQDFFKGFSDTLEMADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIQEFSKPLLPVGRAGVLLAEILHLLCKQMSHKKVGALWRETGLSWKDYLPEGEDVHTFLMEQKLEFTESDCSSSSEALSEKELSAEELNKQLEKLIVEDKANDEQIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADSSSFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPPNLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "length": 1649, "header": "tr|A0A8V0ZHZ1-1|A0A8V0ZHZ1_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4 gamma 3 OS=Gallus gallus OX=9031 GN=EIF4G3 PE=1 SV=1 CANONICAL=A0A8V0ZAW7-1" }, "locus": { "chromosome": "21", "start_pos": 6700275, "end_pos": 6643250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051216.1", "url": "https://www.ensembl.org/id/ENSGALT00010051216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030407.1", "url": "https://www.ensembl.org/id/ENSGALP00010030407.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1355, "end_pos": 1357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" }, { "id": "PS51366", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MI", "eco_id": "ECO_0000259", "start_pos": 1387, "end_pos": 1509, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZAW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW7" }, { "id": "PS51363", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000259", "start_pos": 1582, "end_pos": 1751, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"uniprot_ac": "A0A8V0ZAW2", "uniprot_id": "A0A8V0ZAW2_CHICK", "mass": { "chemical_mass": 157319.0, "monoisotopic_mass": 157319.0 }, "refseq": { "ac": "XP_015154786", "name": "G patch domain-containing protein 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154786" }, "gene_names": [ { "name": "GPATCH8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" } ] }, { "name": "GPATCH8", "type": "synonym", "evidence": [ { "id": "XP_015154786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154786" } ] } ], "protein_names": [ { "name": "G patch domain-containing protein 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015154786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154786" } ] }, { "name": "G-patch domain containing 8", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154786.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154786" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPATCH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2", "locus": { "chromosome": "27", "start_pos": 1172099, "end_pos": 1142651, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021148", "url": "https://www.ensembl.org/id/ENSGALG00010021148" } ] } } ], "crossref": [ { "id": "426522", "url": "https://www.ncbi.nlm.nih.gov/gene/426522", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426522", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426522", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZAW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZAW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRFSRFNEDRDFQGNHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDERKQERALRRLHELAEQRRQPECAPGSGPMFRTTTVAVDEEGGDDDDAAANSSSFTQLSGPGGEMGTDRGFLNVGQGGGGAVPGQAPLQAAQAVSFGIKGALGTPLQKIGVSFSFAKKTPVKLETIASVFKDHVDESSSADGAKADEKGSSDGGGLQKAGEGESTNNSDGKADDDDHDKDSGSLATTLSKLKKMRREDGPTAVEPEYYHYIPPAHCKVKPNFQFLLFMKSTEQTEAENVNKKNTNEVRKGNSPKPKPSKQAEKAAESTVQPKEQSAPESTSQQGKAEQKEAPEDVSVQESKSAAESGLPEPGVPGDAAQPAPSCKDVPEGPRPPPGPFIPVLSKDESTTLQWPSELLIFTKAEPSVSYSCNPLYFDFKLSRNKDAKGKGAEKSKDPGGLCRENIQSAEFGEVSKAKEADSSTDGSGGAESRLLPQGKQEGCLQGKGEGEGEGDESGRSGSGRGKAGKSHKHKKKKKHKKSSRHKRKHKEEPEEKSRKTDLGEEKPRKRRRHRHKKVKSSLSTESERALKAELSEECGHFQKKKRCSQESQRKSLSAEEGSSGKKEDSGASCPEHGPKKRRAARRRCLGPRRSRRSSGDEDDSDEGSHGKRSQYSDDYGSGSERSQSRSASGRGHSSRRSYSSSSDASSDRSRYSRRRSYSDSYSDYSERSRCSKRSQDSEDDSDYNRSKRRKYSSSEDYSSSRSRSRSRSRRSRTRSRGRTRSSSCSRSRSKRRSRSVTGRSWKRSRSYSRGRSTRSHSQRSLSRKGSRGHESPEERRSGRRDFIRSKIYRSQSPHYFRAARGEGAVKKEDGKGEEPRGSQNSSSGTSRASEGDCSPEERNSVTAKLLLEKVQSRKVEKKPCVADEMLAGAGKVGIKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPTVRKPNTKRYEESGMERGEELSDSEGAEDAPLGGQPLLGDAAMGLQDAALEEQKREEEMPSVPLEAPALPECFSSGDLVLPHAFLAAPGDGEALEPMDGGSQPVPVDTAMMPLVPDVEHFPGYVPQGAEPGMEGDRDAGEDSSLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPAAPALQPIHIPQPAAASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLTSHPIHIIPASAIHPGPFTFHPVPHALYPTLLAPRPAAAAAATALHLHPLLHPIFSGQDLQHPPSHGT", 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"length": 1436, "header": "tr|A0A8V0ZAW2-1|A0A8V0ZAW2_CHICK Isoform 1 of G-patch domain containing 8 OS=Gallus gallus OX=9031 GN=GPATCH8 PE=4 SV=1 CANONICAL=A0A8V0ZAW2-1" }, "locus": { "chromosome": "27", "start_pos": 1171470, "end_pos": 1142682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051217.1", "url": "https://www.ensembl.org/id/ENSGALT00010051217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030408.1", "url": "https://www.ensembl.org/id/ENSGALP00010030408.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426522", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426522", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1007, "end_pos": 1009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW2" }, { "id": "PS50157", "database": 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This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3. Essential for late-stage assembly of mtLSU required for efficient translation of mitochondrial DNA encoded proteins; methyltransferase activity is not required for this function. 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAW9-1", "uniprot_ac": "A0A8V0ZAW9", "uniprot_id": "A0A8V0ZAW9_CHICK", "mass": { "chemical_mass": 53004.0, "monoisotopic_mass": 53004.0 }, "refseq": { "ac": "XP_024998672", "name": "LETM1 domain-containing protein LETM2, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998672" }, "gene_names": [ { "name": "LETM2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZAW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ] }, { "name": "LETM2", "type": "synonym", "evidence": [ { "id": "XP_024998672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998672" } ] } ], "protein_names": [ { "name": "LETM1 domain-containing protein LETM2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024998672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998672" } ] }, { "name": "Leucine zipper and EF-hand containing transmembrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024998672.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998672" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LETM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9", "locus": { "chromosome": "22", "start_pos": 2500585, "end_pos": 2495896, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017852", "url": "https://www.ensembl.org/id/ENSGALG00010017852" } ] } } ], "crossref": [ { "id": "A0A8V0ZAW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "426779", "url": "https://www.ncbi.nlm.nih.gov/gene/426779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426779", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAACGCN", "url": "https://omabrowser.org/oma/group/MAACGCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAW9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14009:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14009:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024998672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998672", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRSWSALLALARPRPRPRGSQLLLHSISPCSPAIALVQLVDLHLNRTCVCPSQRQHRARPDPRLPHSAAEAVRSFHTSTRVLQEPQEQPAPSRGAAPAPTPTRGTESPVGRKSWHQTIVGELKHYYNGFHLLWIDTKVAARMVWRLLHGQVLTRRERRRLLRTCADLFRLVPFLVFIIVPFMEFLLPVFLKLFPEMLPSTFETESKKEEKQKKKLNAKLELAKFLQETIAEMAKRNKADTGQGKQFSSYVHQIRHTGHKPSTQEIVRFSKLFEDELTLEHLERPQLVALCKLLELQPIGTNNLLRFQLLLRLRTIRTDDELIAKEGVNGLSVSELQSACRARGMRSLGLSEEQLKEQLRQWLDLHLKENVPPSLLLLSRALYLIDVTPQSLPENKIGETEEVMTSIPEDQESLVDPAPIAQGRKNEEFIPRPTEKLPVSEAPIKPLQQETKLEASQSSKAGANGV", "length": 467, "header": "tr|A0A8V0ZAW9-1|A0A8V0ZAW9_CHICK Isoform 1 of Leucine zipper and EF-hand containing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LETM2 PE=4 SV=1 CANONICAL=A0A8V0ZAW9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9/entry#A0A8V0ZAW9-1", "sequence": { "sequence": "MALRSWSALLALARPRPRPRGSQLLLHSISPCSPAIALVQLVDLHLNRTCVCPSQRQHRARPDPRLPHSAAEAVRSFHTSTRVLQEPQEQPAPSRGAAPAPTPTRGTESPVGRKSWHQTIVGELKHYYNGFHLLWIDTKVAARMVWRLLHGQVLTRRERRRLLRTCADLFRLVPFLVFIIVPFMEFLLPVFLKLFPEMLPSTFETESKKEEKQKKKLNAKLELAKFLQETIAEMAKRNKADTGQGKQFSSYVHQIRHTGHKPSTQEIVRFSKLFEDELTLEHLERPQLVALCKLLELQPIGTNNLLRFQLLLRLRTIRTDDELIAKEGVNGLSVSELQSACRARGMRSLGLSEEQLKEQLRQWLDLHLKENVPPSLLLLSRALYLIDVTPQSLPENKIGETEEVMTSIPEDQESLVDPAPIAQGRKNEEFIPRPTEKLPVSEAPIKPLQQETKLEASQSSKAGANGV", "length": 467, "header": "tr|A0A8V0ZAW9-1|A0A8V0ZAW9_CHICK Isoform 1 of Leucine zipper and EF-hand containing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LETM2 PE=4 SV=1 CANONICAL=A0A8V0ZAW9-1" }, "locus": { "chromosome": "22", "start_pos": 2500022, "end_pos": 2495961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043154.1", "url": "https://www.ensembl.org/id/ENSGALT00010043154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025629.1", "url": "https://www.ensembl.org/id/ENSGALP00010025629.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426779", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B9Z2-1", "protein_name": "Leucine zipper and EF-hand containing transmembrane protein 2", "gene_name": "LETM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFYSYKTVLAIARTRFPSHFVQPTSSSYSPSFAFLHLPDSHLNKTYMKNYGSKKYSHPSQSGNKVLHLRARIFQELHTSTCWLQEVPNKHQQEQTAKKPQVPSPQPTKEAGMKIKEGKRSYRQIIMDELKYYYNGFYLLWIDTKVAARMVWRLLHGQVLTRRERRRLLRTCADFFRLVPFMVFIIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQRKKMAAKLELAKFLQETITEMAKRNRAQLGDASTQFSSYVKQVQTGHKPSTKEIVQFSKLFEDQLTLEHLDRPQLVALCKLLELQSFGTNNLLRFQLLMRLKSIKADDEVIAKEGVNALSVSELQAACRARGMLSLGLTEGQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAPKTDIPLGSPTPPESKENTAGLAPQLKETKQLMPPNHQEHLTQWVNLW", "length": 455 }, "evidence": [ { "id": "A0A8V0ZAW9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2VYF4-1", "protein_name": "LETM1 domain-containing protein LETM2, mitochondrial", "gene_name": "LETM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFYSYNSVLAIARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPSQPGNTVLHPGTRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAPKTDILVELPTFTESKENMVDLAPQLKGTKDEDFIQPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMTAQNSKASSKGA", "length": 491 }, "evidence": [ { "id": "A0A8V0ZAW9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQQ5-1", "protein_name": "LETM1 domain-containing protein LETM2, mitochondrial", "gene_name": "Letm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFYSYNSFLAIFWTRLPGHSVHPPCSHFPPLAFFHLPDSHLRTAYMKNCGSRKYSYPGLTGNNKVHPLRTRLPQKLHTTCWLQNHPGKPQPEQIPEEPKATDPQPTKDDQTEVAEGKWSLRQKIIDEVKYYYNGFSLLWIDTKVAARIVWRLLHGQVLTRRERRRLLRTCADVFRLVPFVVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKMMGAKLEIAKFLQETMTEMAKRNRAKLDDDSSDSSQLSSYVKQVQTGHKPSTKEIVRFSKLFEDQLALEHLRRPQLVALCKLLELQAFGTNNLLRFQLLMTLRSIKADDEVIAKEGVKALSVSELQAACRARGMRSLGLTEEQLRQQLTEWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPSIETPKTNLGIPSSPPPESKEDITDPAPQLNGTKILQAKSQETSQNSKANSKGA", "length": 459 }, "evidence": [ { "id": "A0A8V0ZAW9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TNU7-1", "protein_name": "LETM1 domain-containing protein LETM2, mitochondrial", "gene_name": "Letm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFYSYNSFLAIFWTRLPGHSVYPSCSHFPSLAFLHLPDSHLRTAYIKNCGSRKYSYPSLTGNNKVHPLRTRLPQKLHTTCWLQHVPGKPQLEQTGKPKAASPQPTKEAKTETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGNALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTMAAKLEIAKFLQETMTEMARRNRAKLGDASSQLSSYVKQVQTGHKPSTKEIVRFSKLFKDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGMRSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPNIETPKPNLGIPTPPPPESKENLTDSAPQLKGTKDEEFIQLPPVPSSLIAPAATISKEAILQAKSQETSQNSKADSKGA", "length": 480 }, "evidence": [ { "id": "A0A8V0ZAW9", "url": "https://omabrowser.org/oma/group/A0A8V0ZAW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" }, { "name": "mitochondrial calcium ion transmembrane transport", "id": "GO:0006851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006851", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZAW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW9" }, { "id": "PS51758", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51758" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Letm1 RBD", "eco_id": "ECO_0000259", "start_pos": 215, "end_pos": 417, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 102 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB02-1", "uniprot_ac": "A0A8V0ZB02", "uniprot_id": "TM63B_CHICK", "mass": { "chemical_mass": 92953.0, "monoisotopic_mass": 92953.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM63B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02" } ] } ], "protein_names": [ { "name": "Mechanosensitive cation channel TMEM63B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 63B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mechanosensitive cation channel with low conductance and high activation threshold (By similarity). Osmosensitive cation channel preferentially activated by hypotonic stress (By similarity). 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"Protein" ] } ], "sequence": { "sequence": "MLPYVIATLGSAGSTCKASTCSNSTKDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFVFSILRKVAWDYGRLALVTDADSIASALHSDNHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVAVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLNSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAEPEKIKKHFEEAYANCTVLEARPCYDVARLMFLDAERRKAERGRIYFTNLQSKENTPSMINPKPCGHLCCCVIRGCEEVEAIEYYTKLEEKLKDDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNACKCQGCACRGEPRASSCSESLHVSNWTVSYAPDPQNIYWEHLSIRGFIWWIRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDVFFRWLFDKKFLAEAAVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTEVDTTESRQNGRPATNLPAPKSAKYIAQVLQDSSPEGEATESEEQGSQDEELITTDGMNDTDFQSCEDSLIENEIRQ", "length": 816, "header": "sp|A0A8V0ZB02-1|TM63B_CHICK Isoform 1 of Mechanosensitive cation channel TMEM63B OS=Gallus gallus OX=9031 GN=TMEM63B PE=3 SV=1 CANONICAL=A0A8V0ZB02-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02/entry#A0A8V0ZB02-1", "sequence": { "sequence": 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"locus": { "chromosome": "3", "start_pos": 30041242, "end_pos": 30025543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047411.1", "url": "https://www.ensembl.org/id/ENSGALT00010047411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028092.1", "url": "https://www.ensembl.org/id/ENSGALP00010028092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] }, { "title": "Membrane structure-responsive lipid scramblase activity of the TMEM63/OSCA family.", "journal": "FEBS letters", "date": "2024-12-23", "authors": "Miyata Yugo, Nishimura Megumi, Nagata Aya, Jing Xu, Sultan Cheryl S, Kuribayashi Risa, Takahashi Katsuya, Lee Yongchan, Nishizawa Tomohiro, Segawa Katsumori", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02" } ], "reference": [ { "type": "PubMed", "id": "39716028", "url": "https://glygen.org/publication/PubMed/39716028" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB02" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB02", "url": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB22-1", "uniprot_ac": "A0A8V0ZB22", "uniprot_id": "A0A8V0ZB22_CHICK", "mass": { "chemical_mass": 99976.0, "monoisotopic_mass": 99976.0 }, "refseq": { "ac": "XP_015142682", "name": "probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142682" }, "gene_names": [ { "name": "ACCS", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" } ] }, { "name": "ACCS", "type": "synonym", "evidence": [ { "id": "XP_015142682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142682" } ] } ], "protein_names": [ { "name": "1-aminocyclopropane-1-carboxylate synthase-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22/entry#names_and_taxonomy" } ] }, { "name": "probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142682" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142682.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142682" } ] }, { "annotation": "Does not catalyze the synthesis of 1-aminocyclopropane-1-carboxylate but is capable of catalyzing the deamination of L-vinylglycine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F2#function" }, { "database": "UniProtKB", "id": "ARBA00057291", "url": "https://www.uniprot.org/uniprotkb/ARBA00057291#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACCS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZB22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00609", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00609", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423170", "url": "https://www.ncbi.nlm.nih.gov/gene/423170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423170", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423170", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYHHQFT", "url": "https://omabrowser.org/oma/group/SYHHQFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4F2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4F7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB22", "url": "https://www.orthodb.org/?gene=A0A8V0ZB22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43795", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43795", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43795:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43795:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142682", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFRGKKYERGSNWSDPEVVELLQLWADESVQLELESCLRNQHVFNRIAEVLREKGIHRTGDQCREKIKKMKLEYRRIKDNSKAPRGGRTWKFYDVMDRVLNSRPALAYGPMGGGVMATQVLPGGLVDGYHHQFAAPALPFGHSQHPELMEIKCEEVNSDEDCLTPEPSAAVSYQQGCPEEHEMERAFLERAQNDSPISRVEIPIESSVSPSGFSEPSMANSSRMQNAVPRHGFSALHRLRKKRKGQRAKDPLDDLLLKTLTSQRAMEERFLQMEERRFQRDLDVEERRMQLEQRRFELEREHEFRMFNVFAQMLSILKQSHGGGASPSLAMPRGLDFSQTLWELMGREGGGDQRGPRARGLARSRGDMCGFCPPEGFRRSPYLSARGNVANIFRGSDEEGYKAYHADKYDEDTNPNGIINFGTSENKLCFDLMSKRLKEQLTQTDMNLMEPLLLQYPDWKGHMFLREEVARFLTYYCKAPAPLKAENVIVLNGCGSLFSALATVLCDPGEAVLIATPFYGGITQSVFLYGNVKLVYAYLDSKITGTSTRPFQLTVEKLEKALQDALAEGVTVRALILLNPQNPLGDIYSLSELRDYLEFAKRHELHVIVDEIYMLSVFDESATFHSVLGMDRLPDPQRTHVMWGISKDFAVSGIRFGTLYTENQDVANAVASLCYFHGVCGPVQHKVAQLLRDREWINQVYLRANHARLKAAHTYVTDELKTLGVPFLNRNAGFFVWIDFRKYLRTGTFEEEMLLWRRFLDNKVLLSCGKAFECSEPGWFRIIFADKTHRLQLGMQRIRKVLEEREQEILSEEKEQPCQSDQDGKADSTDEVIIVSHHQESSCAGSSNLSDLIGLLQQQMRSSDWLQKNTAEQLA", "length": 876, "header": "tr|A0A8V0ZB22-1|A0A8V0ZB22_CHICK Isoform 1 of 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Gallus gallus OX=9031 GN=ACCS PE=4 SV=1 CANONICAL=A0A8V0ZB22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22/entry#A0A8V0Z4F2-1", "sequence": { "sequence": "MDFRGKKYERGSNWSDPEVVELLQLWADESVQLELESCLRNQHVFNRIAEVLREKGIHRTGDQCREKIKKMKLEYRRIKDNSKAPRGGRTWKFYDVMDRVLNSRPALAYGPMGGGVMATQVLPGGLVDGYHHQFAAPALPFGHSQHPELMEIKCEEVNSDEDCLTPEPSAAVSYQQGCPEEHEMERAFLERAQNDSPISRVEIPIESSVSPSGFSEPSMANSSRMQNAVPRHGFSALHRLRKKRKGQRAKDPLDDLLLKTLTSQRAMEERFLQMEERRFQRDLDVEERRMQLEQRRFELEREHEFRMFNVFAQMLSILKQSHGGGASPSLAMPRGLDFSQTLWELMGREGGGDQRGPRARGLARSRGDMCGFCPPEGFRRSPYLSARGNVANIFRGSDEEGYKAYHADKYDEDTNPNGIINFGTSENKLCFDLMSKRLTQTDMNLMEPLLLQYPDWKGHMFLREEVARFLTYYCKAPAPLKAENVIVLNGCGSLFSALATVLCDPGEAVLIATPFYGGITQSVFLYGNVKLVYAYLDSKITGTSTRPFQLTVEKLEKALQDALAEGVTVRALILLNPQNPLGDIYSLSELRDYLEFAKRHELHVIVDEIYMLSVFDESATFHSVLGMDRLPDPQRTHVMWGISKDFAVSGIRFGTLYTENQDVANAVASLCYFHGVCGPVQHKVAQLLRDREWINQVYLRANHARLKAAHTYVTDELKTLGVPFLNRNAGFFVWIDFRKYLRTGTFEEEMLLWRRFLDNKVLLSCGKAFECSEPGWFRIIFADKTHRLQLGMQRIRKVLEEREQEILSEEKEQPCQSDQDGKADSTDEVIIVSHHQESSCAGSSNLSDLIGLLQQQMRSSDWLQKNTAEQLA", "length": 872, "header": "tr|A0A8V0Z4F2-1|A0A8V0Z4F2_CHICK Computationally mapped isoform of 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Gallus gallus OX=9031 GN=ACCS PE=4 SV=1 CANONICAL=A0A8V0ZB22-1" }, "locus": { "chromosome": "5", "start_pos": 21256692, "end_pos": 21243378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047476.1", "url": "https://www.ensembl.org/id/ENSGALT00010047476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028113.1", "url": "https://www.ensembl.org/id/ENSGALP00010028113.1" } ] } }, { "isoform_ac": "A0A8V0Z4F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22/entry#A0A8V0Z4F7-1", "sequence": { "sequence": "MANSSRMQNAVPRHGFSALHRLRKKRKGQRAKDPLDDLLLKTLTSQRAMEERFLQMEERRFQRDLDVEERRMQLEQRRFELEREHEFRMFNVFAQMLSILKQSHGGGASPSLAMPRGLDFSQTLWELMGREGGGDQRGPRARGLARSRGDMCGFCPPEGFRRSPYLSARGNVANIFRGSDEEGYKAYHADKYDEDTNPNGIINFGTSENKLCFDLMSKRLKEQLTQTDMNLMEPLLLQYPDWKGHMFLREEVARFLTYYCKAPAPLKAENVIVLNGCGSLFSALATVLCDPGEAVLIATPFYGGITQSVFLYGNVKLVYAYLDSKITGTSTRPFQLTVEKLEKALQDALAEGVTVRALILLNPQNPLGDIYSLSELRDYLEFAKRHELHVIVDEIYMLSVFDESATFHSVLGMDRLPDPQRTHVMWGISKDFAVSGIRFGTLYTENQDVANAVASLCYFHGVCGPVQHKVAQLLRDREWINQVYLRANHARLKAAHTYVTDELKTLGVPFLNRNAGFFVWIDFRKYLRTGTFEEEMLLWRRFLDNKVLLSCGKAFECSEPGWFRIIFADKTHRLQLGMQRIRKVLEEREQEILSEEKEQPCQSDQDGKADSTDEVIIVSHHQESSCAGSSNLSDLIGLLQQQMRSSDWLQKNTAEQLA", "length": 658, "header": "tr|A0A8V0Z4F7-1|A0A8V0Z4F7_CHICK Computationally mapped isoform of 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Gallus gallus OX=9031 GN=ACCS PE=4 SV=1 CANONICAL=A0A8V0ZB22-1" }, "locus": { "chromosome": "5", "start_pos": 21256692, "end_pos": 21245235, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047485.1", "url": "https://www.ensembl.org/id/ENSGALT00010047485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028118.1", "url": "https://www.ensembl.org/id/ENSGALP00010028118.1" } ] } }, { "isoform_ac": "A0A8V0ZB22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22/entry#A0A8V0ZB22-1", "sequence": { "sequence": "MDFRGKKYERGSNWSDPEVVELLQLWADESVQLELESCLRNQHVFNRIAEVLREKGIHRTGDQCREKIKKMKLEYRRIKDNSKAPRGGRTWKFYDVMDRVLNSRPALAYGPMGGGVMATQVLPGGLVDGYHHQFAAPALPFGHSQHPELMEIKCEEVNSDEDCLTPEPSAAVSYQQGCPEEHEMERAFLERAQNDSPISRVEIPIESSVSPSGFSEPSMANSSRMQNAVPRHGFSALHRLRKKRKGQRAKDPLDDLLLKTLTSQRAMEERFLQMEERRFQRDLDVEERRMQLEQRRFELEREHEFRMFNVFAQMLSILKQSHGGGASPSLAMPRGLDFSQTLWELMGREGGGDQRGPRARGLARSRGDMCGFCPPEGFRRSPYLSARGNVANIFRGSDEEGYKAYHADKYDEDTNPNGIINFGTSENKLCFDLMSKRLKEQLTQTDMNLMEPLLLQYPDWKGHMFLREEVARFLTYYCKAPAPLKAENVIVLNGCGSLFSALATVLCDPGEAVLIATPFYGGITQSVFLYGNVKLVYAYLDSKITGTSTRPFQLTVEKLEKALQDALAEGVTVRALILLNPQNPLGDIYSLSELRDYLEFAKRHELHVIVDEIYMLSVFDESATFHSVLGMDRLPDPQRTHVMWGISKDFAVSGIRFGTLYTENQDVANAVASLCYFHGVCGPVQHKVAQLLRDREWINQVYLRANHARLKAAHTYVTDELKTLGVPFLNRNAGFFVWIDFRKYLRTGTFEEEMLLWRRFLDNKVLLSCGKAFECSEPGWFRIIFADKTHRLQLGMQRIRKVLEEREQEILSEEKEQPCQSDQDGKADSTDEVIIVSHHQESSCAGSSNLSDLIGLLQQQMRSSDWLQKNTAEQLA", "length": 876, "header": "tr|A0A8V0ZB22-1|A0A8V0ZB22_CHICK Isoform 1 of 1-aminocyclopropane-1-carboxylate synthase-like protein 1 OS=Gallus gallus OX=9031 GN=ACCS PE=4 SV=1 CANONICAL=A0A8V0ZB22-1" }, "locus": { "chromosome": "5", "start_pos": 21256692, "end_pos": 21243378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047469.1", "url": "https://www.ensembl.org/id/ENSGALT00010047469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028112.1", "url": "https://www.ensembl.org/id/ENSGALP00010028112.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423170", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423170", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" } ], "pmid": "" }, { "name": "transaminase activity", "id": "GO:0008483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008483", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" }, { "id": "PF00155", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminotransferase class I/classII large", "eco_id": "ECO_0000259", "start_pos": 419, "end_pos": 790, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZB22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB22" }, { "id": "PF13837", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 99, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 849, "end_pos": 851 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB38-1", "uniprot_ac": "A0A8V0ZB38", "uniprot_id": "A0A8V0ZB38_CHICK", "mass": { "chemical_mass": 131796.0, "monoisotopic_mass": 131796.0 }, "refseq": { "ac": "XP_004945373", "name": "MHC class II transactivator isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945373" }, "gene_names": [ { "name": "CIITA", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "name": "CIITA", "type": "synonym", "evidence": [ { "id": "XP_004945373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945373" } ] } ], "protein_names": [ { "name": "MHC class II transactivator", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38/entry#names_and_taxonomy" } ] }, { "name": "MHC class II transactivator isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945373" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945373.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945373" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CIITA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZB38", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB38", "database": "AlphaFoldDB", "categories": [] }, { "id": "416633", "url": "https://www.ncbi.nlm.nih.gov/gene/416633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416633", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416633", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTMLIFD", "url": "https://omabrowser.org/oma/group/KTMLIFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R7", "url": "https://www.orthodb.org/?gene=A0A8V0Z3R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB38", "url": "https://www.orthodb.org/?gene=A0A8V0ZB38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH17", "url": "https://www.orthodb.org/?gene=A0A8V0ZH17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47189:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47189:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z3R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMPKKLSVNLHIQEAEIGSASLPQAAELSLMFAVRVSSSQFSGGQTFSICSSAPQDDNKRQIMDSTSVSENGYLDLLLCDIDPMHLFAFSDPKSSGNEGEFFADPEIDTYNYEQFNNMDFLCAVENDENEDELYLSSNAKDAYARIAELAEYVLKDPHEKQVEDEFAGNLILDEMALENTEKFTDVKMQKCHKRTFSGSAENCSDASEPKYKKIVDAPAVSTGNGCFLTMSLNSHSSDCTSLTHQHMSFSVPTINAPGSFVIPGSSVPLIPECLPLGMKDNRENVDFVDPAQQKINYFLGNGTSNAIRYPELTSSTELMVSPSFQVNLNGLEMFKEVQVPEILSEESSRRPRSVEAFCTSLMDYFRDVCKSVSVEREMSLDHMYIDGTLRQSQIETKPGKNSVKSVERDSVTYSQQEKEEAVIERSQIFQMPGGKELETKVIVVLGKAGMGKSVLVQKICQDWSNGEFSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTKVLLVFDGLEGLHGHENSPQCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTKEKVCQYVSKVDKTIEIVGFSPWQRELYISKYFEGLPSCDNALNLIKEHEYLFSHCYSPVMCRFVCFLCETILEMGDQGLPSTLTTLFLKFVQQKIMPTQTDVTDVTLAQNQENLATLACIAWYLGEKHLSAMKSDLLPSKEVKEFALKNGFFLPFAFPKHSDTGEEEYGTMFSDFVIQNFLGALHLILTEGIKNKSLIKYLSFPSKKKKPYNWLHFVPRFLAGLLFLQDDTYFCSLSNKGVKKSTKKQKMLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVALRLKPDLSFLGIVLTPPDVHVLSSTLKRSRKEFSLDLQNSSIDTHGLKDLVGLKNVVSFRASLSDTIRLWKYLEQTKDYELLRVSTEKFVLDPFKAKTMRDIIDLSDLVEMQEIIINRVQDDSGCSSYQIPAIKNLRKLEFALGPACGLQGFLKLVEILAAFPSLQHLDLDALSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALPSLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNLVMWNPTIPYGVLEHLQQLDSRISV", "length": 1171, "header": "tr|A0A8V0ZB38-1|A0A8V0ZB38_CHICK Isoform 1 of MHC class II transactivator OS=Gallus gallus OX=9031 GN=CIITA PE=4 SV=1 CANONICAL=A0A8V0ZB38-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38/entry#A0A8V0Z3R7-1", "sequence": { "sequence": "MDSTSVSENGYLDLLLCDIDPMHLFAFSDPKSSGNEGEFFADPEIDTYNYEQFNNMDFLCAVENDENEDELYLSSNAKDAYARIAELAEYVLKDPHEKQVEDEFAGNLILDEMALENTEKFTDVKMQKCHKRTFSGSAENCSDASEPKYKKIVDAPAVSTGNGCFLTMSLNSHSSDCTSLTHQHMSFSVPTINAPGSFVIPGSSVPLIPECLPLGMKDNRENVDFVDPAQQKINYFLGNGTSNAIRYPELTSSTELMVSPSFQVNLNGLEMFKEVQVPEILSEESSRRPRSVEAFCTSLMDYFRDVCKSVSVEREMSLDHMYIDGTLRQSQIETKPGKNSVKSVERDSVTYSQQEKEEAVIERSQIFQMPGGKELETKVIVVLGKAGMGKSVLVQKICQDWSNGEFSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTKVLLVFDGLEGLHGHENSPQCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTKEKVCQYVSKVDKTIEIVGFSPWQRELYISKYFEGLPSCDNALNLIKEHEYLFSHCYSPVMCRFVCFLCETILEMGDQGLPSTLTTLFLKFVQQKIMPTQTDVTDVTLAQNQENLATLACIAWYLGEKHLSAMKSDLLPSKEVKEFALKNGFFLPFAFPKHSDTGEEEYGTMFSDFVIQNFLGALHLILTEGIKNKSLIKYLSFPSKKKKPYNWLHFVPRFLAGLLFLQDDTYFCSLSNKGVKKSTKKQKMLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVALRLKPDLSFLGIVLTPPDVHVLSSTLKRSRKEFSLDLQNSSIDTHGLKDLVGLKNVVSFRASLSDTIRLWKYLEQTKDYELLRVSTEKFVLDPFKAKTMRDIIDLSDLVEMQEIIINRVQDDSGCSSYQIPAIKNLRKLEFALGPACGLQGFLKLVEILAAFPSLQHLDLDALSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALPSLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNLVMWNPTIPYGVLEHLQQLDSRISV", "length": 1109, "header": "tr|A0A8V0Z3R7-1|A0A8V0Z3R7_CHICK Computationally mapped isoform of MHC class II transactivator OS=Gallus gallus OX=9031 GN=CIITA PE=4 SV=1 CANONICAL=A0A8V0ZB38-1" }, "locus": { "chromosome": "14", "start_pos": 9098400, "end_pos": 9080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046851.1", "url": "https://www.ensembl.org/id/ENSGALT00010046851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027876.1", "url": "https://www.ensembl.org/id/ENSGALP00010027876.1" } ] } }, { "isoform_ac": "A0A8V0ZB38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38/entry#A0A8V0ZB38-1", "sequence": { "sequence": "MMPKKLSVNLHIQEAEIGSASLPQAAELSLMFAVRVSSSQFSGGQTFSICSSAPQDDNKRQIMDSTSVSENGYLDLLLCDIDPMHLFAFSDPKSSGNEGEFFADPEIDTYNYEQFNNMDFLCAVENDENEDELYLSSNAKDAYARIAELAEYVLKDPHEKQVEDEFAGNLILDEMALENTEKFTDVKMQKCHKRTFSGSAENCSDASEPKYKKIVDAPAVSTGNGCFLTMSLNSHSSDCTSLTHQHMSFSVPTINAPGSFVIPGSSVPLIPECLPLGMKDNRENVDFVDPAQQKINYFLGNGTSNAIRYPELTSSTELMVSPSFQVNLNGLEMFKEVQVPEILSEESSRRPRSVEAFCTSLMDYFRDVCKSVSVEREMSLDHMYIDGTLRQSQIETKPGKNSVKSVERDSVTYSQQEKEEAVIERSQIFQMPGGKELETKVIVVLGKAGMGKSVLVQKICQDWSNGEFSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTKVLLVFDGLEGLHGHENSPQCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTKEKVCQYVSKVDKTIEIVGFSPWQRELYISKYFEGLPSCDNALNLIKEHEYLFSHCYSPVMCRFVCFLCETILEMGDQGLPSTLTTLFLKFVQQKIMPTQTDVTDVTLAQNQENLATLACIAWYLGEKHLSAMKSDLLPSKEVKEFALKNGFFLPFAFPKHSDTGEEEYGTMFSDFVIQNFLGALHLILTEGIKNKSLIKYLSFPSKKKKPYNWLHFVPRFLAGLLFLQDDTYFCSLSNKGVKKSTKKQKMLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVALRLKPDLSFLGIVLTPPDVHVLSSTLKRSRKEFSLDLQNSSIDTHGLKDLVGLKNVVSFRASLSDTIRLWKYLEQTKDYELLRVSTEKFVLDPFKAKTMRDIIDLSDLVEMQEIIINRVQDDSGCSSYQIPAIKNLRKLEFALGPACGLQGFLKLVEILAAFPSLQHLDLDALSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALPSLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNLVMWNPTIPYGVLEHLQQLDSRISV", "length": 1171, "header": "tr|A0A8V0ZB38-1|A0A8V0ZB38_CHICK Isoform 1 of MHC class II transactivator OS=Gallus gallus OX=9031 GN=CIITA PE=4 SV=1 CANONICAL=A0A8V0ZB38-1" }, "locus": { "chromosome": "14", "start_pos": 9108514, "end_pos": 9080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046857.1", "url": "https://www.ensembl.org/id/ENSGALT00010046857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027879.1", "url": "https://www.ensembl.org/id/ENSGALP00010027879.1" } ] } }, { "isoform_ac": "A0A8V0ZH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38/entry#A0A8V0ZH17-1", "sequence": { "sequence": "MELQDNKRQIMDSTSVSENGYLDLLLCDIDPMHLFAFSDPKSSGNEGEFFADPEIDTYNYEQFNNMDFLCAVENDENEDELYLSSNAKDAYARIAELAEYVLKDPHEKQVEDEFAGNLILDEMALENTEKFTDVKMQKCHKRTFSGSAENCSDASEPKYKKIVDAPAVSTGNGCFLTMSLNSHSSDCTSLTHQHMSFSVPTINAPGSFVIPGSSVPLIPECLPLGMKDNRENVDFVDPAQQKINYFLGNGTSNAIRYPELTSSTELMVSPSFQVNLNGLEMFKEVQVPEILSEESSRRPRSVEAFCTSLMDYFRDVCKSVSVEREMSLDHMYIDGTLRQSQIETKPGKNSVKSVERDSVTYSQQEKEEAVIERSQIFQMPGGKELETKVIVVLGKAGMGKSVLVQKICQDWSNGEFSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTKVLLVFDGLEGLHGHENSPQCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTKEKVCQYVSKVDKTIEIVGFSPWQRELYISKYFEGLPSCDNALNLIKEHEYLFSHCYSPVMCRFVCFLCETILEMGDQGLPSTLTTLFLKFVQQKIMPTQTDVTDVTLAQNQENLATLACIAWYLGEKHLSAMKSDLLPSKEVKEFALKNGFFLPFAFPKHSDTGEEEYGTMFSDFVIQNFLGALHLILTEGIKNKSLIKYLSFPSKKKKPYNWLHFVPRFLAGLLFLQDDTYFCSLSNKGVKKSTKKQKMLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVALRLKPDLSFLGIVLTPPDVHVLSSTLKRSRKEFSLDLQNSSIDTHGLKDLVGLKNVVSFRASLSDTIRLWKYLEQTKDYELLRVSTEKFVLDPFKAKTMRDIIDLSDLVEMQEIIINRVQDDSGCSSYQIPAIKNLRKLEFALGPACGLQGFLKLVEILAAFPSLQHLDLDALSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALPSLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNLVMWNPTIPYGVLEHLQQLDSRISV", "length": 1119, "header": "tr|A0A8V0ZH17-1|A0A8V0ZH17_CHICK Computationally mapped isoform of MHC class II transactivator OS=Gallus gallus OX=9031 GN=CIITA PE=4 SV=1 CANONICAL=A0A8V0ZB38-1" }, "locus": { "chromosome": "14", "start_pos": 9103348, "end_pos": 9080596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046853.1", "url": "https://www.ensembl.org/id/ENSGALT00010046853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027877.1", "url": "https://www.ensembl.org/id/ENSGALP00010027877.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416633", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416633", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated 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"ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_419303.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419303" } ] }, { "annotation": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z464", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z464#function" }, { "database": "UniProtKB", "id": "ARBA00045696", "url": "https://www.uniprot.org/uniprotkb/ARBA00045696#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANAPC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40", "locus": { "chromosome": "3", "start_pos": 3336766, "end_pos": 3370601, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017890", "url": "https://www.ensembl.org/id/ENSGALG00010017890" } ] } } ], "crossref": [ { "id": "421228", "url": "https://www.ncbi.nlm.nih.gov/gene/421228", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MQPPDSR", "url": "https://omabrowser.org/oma/group/MQPPDSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z464", "url": "https://www.orthodb.org/?gene=A0A8V0Z464", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB40", "url": "https://www.orthodb.org/?gene=A0A8V0ZB40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12827:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12827:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18122", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18122", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z464", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z464", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z464-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z464-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDHSEERATMIAAGDLQEFIPRGREHCRRHPGAHNLQPRELQPASELCSSDGAAGLVGSLREVTIHERQRESWQLRKGVSDFGEEVDYDEELYVASNMVIWSKGSKTEASAAYKAFSVDSPVLQALWCDFTIQQEKSDKADVSGGKEIVQKCVCILQSSCVNVHSIDGKDYVAALPFQVANIWPTKFGLLLERSGSSHEVPPSPPREPLPTMFSMLHPLDEITPLVCKSGAGVFGSARVQYVADYTLRIVFVNAEPSIVMTYDTVQSLHTVWALRRVKPEEQNMVLKFSEQLGTPQNVAASSSLTAQLRSLSKGDSPMASPFQNYSSIHSQSRSVSSPSMQSRSPSISNMAALSRSHSPALGVHSFSGVQRFNSSSNVQSPRRHSITHSPESTCSDSFLVTETEPIVPELCIDHLWTEAITKMREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKSQLIFGSVTNIQAKDAAPVQGVDTLLVLEGSGNLVLYSGIVRVGKVFIPGLPAPSLTMSNQMPRPSTPLDSVSTPSKTLNKHLGPLEESMLLSPVPELRDSSKLHDSTYVEDCTFQQHGTFIHALRDPVHNRVTLELSSNTMVRITIPEIATSELVKTCLQGVKAILPKEIAVQMLVKWYNAYNAPGGPSYRLEWNLFVTCLMNMMGYNTEKLTWTRNLNVGGSPSPVSAPKKARPSETGSDEDWEYLLSSDYHRNFESHPLSRVLGLDPLEVLAPKDDFLQSLSLDYSTLLFTHIPAIFFVLHLVYEEFKLNLLMGEENRSLVVLLVQLARDLKLEAYIDYYYRDYPALVKSSGQTCIIDQGFMHHPAFFSAEPPSIFQWLSSCLKGGSVQPYPYLPGICERSKLVILSVALYILGDESAVSNEASPYLYKITSGQQKQQIEQDDNRCCFGHSTSISSLAEKLIIWLTNIGFTLRDLETLPFGVALPIRDAIYYCREQPASDWPEAVCVLIGRQDLSRQACDGNLLKSKSSVGPVLSSDSPSGAESEEDEDGMNNMNDEVMSLIWSKDLRVQEVRRLLQSARPVRVNVVQMPEASDHDFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPIPAEQLPIPKLNLTGRAPPRNSTVDLNSGNIDVPPNMACWASFHNGVAAGLKIAPASRIDSSWIIYNKPKNAEQANEYAGFLMALGLSGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMAITRLLSIHIPALLPPTSTELDVPHNVQVAAVIGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLASGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLAFAMIYLKTNNRSIADWLQAPDTMYLLDFVKPEFLLLRTLARCLILWDDIMPSTEWVDSNVPQIIRENSIPLHATELPSSEDLSLETLMQAHVYIIAGACLSLGFRFAGSENKAAFNCLDKYATDFLKSLSAPTASIIGHYNLETCLSVLLLSLAMVVAGSGNLKVLQLCRFMHKKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPVHSTDNRYHLQALRHLYVLAADPRLLIPVDVDSNTPCYALIEVTFKGTQWYAETTEEMMAPTLLPELHLLKQIRVKGPRYWELLIDLSNETNHLKSILSKGGVLYVKLRAGQLSYKEDPMGWRSFSAQTITHGNEARSFKPEDISAFTSDPALLLFAEYFCKPTVNMGQKQEMLDFFSSILYECVTQEKPEMLPTYIAIDQAVRRLERGEMSETFELGQIKLVLEFFNSRCHQGRMSRNPSRGLFMNSEFLPVMKCTIDKALDQWLQAGGDACLRSYLSRQPKDESQQNMLACFLVYHSVPMPGQLAAGGLDGITNFSEMLLKFKQWNVLVRALLRLAPVLLKNPQSMVL", "length": 1948, "header": "tr|A0A8V0ZB40-1|A0A8V0ZB40_CHICK Isoform 1 of Anaphase-promoting complex subunit 1 OS=Gallus gallus OX=9031 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A8V0ZB40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z464-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40/entry#A0A8V0Z464-1", "sequence": { "sequence": "MERITLLLYPSKLQTSGQQNLVCYWSVVVLHMKYLQVHPAGVFGSARVQYVADYTLRIVFVNAEPSIVMTYDTVQSLHTVWALRRVKPEEQNMVLKFSEQLGTPQNVAASSSLTAQLRSLSKGDSPMASPFQNYSSIHSQSRSVSSPSMQSRSPSISNMAALSRSHSPALGVHSFSGVQRFNSSSNVQSPRRHSITHSPESTCSDSFLVTETEPIVPELCIDHLWTEAITKMREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKSQLIFGSVTNIQAKDAAPVQGVDTLLVLEGSGNLVLYSGIVRVGKVFIPGLPAPSLTMSNQMPRPSTPLDSVSTPSKTLNKHLGPLEESMLLSPVPELRDSSKLHDSTYVEDCTFQQHGTFIHALRDPVHNRVTLELSSNTMVRITIPEIATSELVKTCLQGVKAILPKEIAVQMLVKWYNAYNAPGGPSYRLEWNLFVTCLMNMMGYNTEKLTWTRNLNVGGSPSPVSAPKKARPSETGSDEDWEYLLSSDYHRNFESHPLSRVLGLDPLEVLAPKDDFLQSLSLDYSTLLFTHIPAIFFVLHLVYEEFKLNLLMGEENRSLVVLLVQLARDLKLEAYIDYYYRDYPALVKSSGQTCIIDQGFMHHPAFFSAEPPSIFQWLSSCLKGGSVQPYPYLPGICERSKLVILSVALYILGDESAVSNEASPYLYKITSGQQKQQIEQDDNRCCFGHSTSISSLAEKLIIWLTNIGFTLRDLETLPFGVALPIRDAIYYCREQPASDWPEAVCVLIGRQDLSRQACDGNLLKSKSSVGPVLSSDSPSGAESEEDEDGMNNMNDEVMSLIWSKDLRVQEVRRLLQSARPVRVNVVQMPEASDHDFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPIPAEQLPIPKLNLTGRAPPRNSTVDLNSGNIDVPPNMACWASFHNGVAAGLKIAPASRIDSSWIIYNKPKNAEQANEYAGFLMALGLSGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMAITRLLSIHIPALLPPTSTELDVPHNVQVAAVIGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLASGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLAFAMIYLKTNNRSIADWLQAPDTMYLLDFVKPEFLLLRTLARCLILWDDIMPSTEWVDSNVPQIIRENSIPLHATELPSSEDLSLETLMQAHVYIIAGACLSLGFRFAGSENKAAFNCLDKYATDFLKSLSAPTASIIGHYNLETCLSVLLLSLAMVVAGSGNLKVLQLCRFMHKKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPVHSTDNRYHLQALRHLYVLAADPRLLIPVDVDSNTPCYALIEVTFKGTQWYAETTEEMMAPTLLPELHLLKQIRVKGPRYWELLIDLSNETNHLKSILSKGGVLYVKLRAGQLSYKEDPMGWRSFSAQTITHGNEARSFKPEDISAFTSDPALLLFAEYFCKPTVNMGQKQEMLDFFSSILYECVTQEKPEMLPTYIAIDQAVRRLERGEMSETFELGQIKLVLEFFNSRCHQGRMSRNPSRGLFMNSEFLPVMKCTIDKALDQWLQAGGDACLRSYLSRQPKDESQQNMLACFLVYHSVPMPGQLAAGGLDGITNFSEMLLKFKQWNVLVRALLRLAPVLLKNPQSMVL", "length": 1756, "header": "tr|A0A8V0Z464-1|A0A8V0Z464_CHICK Computationally mapped isoform of Anaphase-promoting complex subunit 1 OS=Gallus gallus OX=9031 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A8V0ZB40-1" }, "locus": { "chromosome": "3", "start_pos": 3369344, "end_pos": 3337009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043268.1", "url": "https://www.ensembl.org/id/ENSGALT00010043268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025712.1", "url": "https://www.ensembl.org/id/ENSGALP00010025712.1" } ] } }, { "isoform_ac": "A0A8V0ZB40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40/entry#A0A8V0ZB40-1", "sequence": { "sequence": "MSDHSEERATMIAAGDLQEFIPRGREHCRRHPGAHNLQPRELQPASELCSSDGAAGLVGSLREVTIHERQRESWQLRKGVSDFGEEVDYDEELYVASNMVIWSKGSKTEASAAYKAFSVDSPVLQALWCDFTIQQEKSDKADVSGGKEIVQKCVCILQSSCVNVHSIDGKDYVAALPFQVANIWPTKFGLLLERSGSSHEVPPSPPREPLPTMFSMLHPLDEITPLVCKSGAGVFGSARVQYVADYTLRIVFVNAEPSIVMTYDTVQSLHTVWALRRVKPEEQNMVLKFSEQLGTPQNVAASSSLTAQLRSLSKGDSPMASPFQNYSSIHSQSRSVSSPSMQSRSPSISNMAALSRSHSPALGVHSFSGVQRFNSSSNVQSPRRHSITHSPESTCSDSFLVTETEPIVPELCIDHLWTEAITKMREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKSQLIFGSVTNIQAKDAAPVQGVDTLLVLEGSGNLVLYSGIVRVGKVFIPGLPAPSLTMSNQMPRPSTPLDSVSTPSKTLNKHLGPLEESMLLSPVPELRDSSKLHDSTYVEDCTFQQHGTFIHALRDPVHNRVTLELSSNTMVRITIPEIATSELVKTCLQGVKAILPKEIAVQMLVKWYNAYNAPGGPSYRLEWNLFVTCLMNMMGYNTEKLTWTRNLNVGGSPSPVSAPKKARPSETGSDEDWEYLLSSDYHRNFESHPLSRVLGLDPLEVLAPKDDFLQSLSLDYSTLLFTHIPAIFFVLHLVYEEFKLNLLMGEENRSLVVLLVQLARDLKLEAYIDYYYRDYPALVKSSGQTCIIDQGFMHHPAFFSAEPPSIFQWLSSCLKGGSVQPYPYLPGICERSKLVILSVALYILGDESAVSNEASPYLYKITSGQQKQQIEQDDNRCCFGHSTSISSLAEKLIIWLTNIGFTLRDLETLPFGVALPIRDAIYYCREQPASDWPEAVCVLIGRQDLSRQACDGNLLKSKSSVGPVLSSDSPSGAESEEDEDGMNNMNDEVMSLIWSKDLRVQEVRRLLQSARPVRVNVVQMPEASDHDFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPIPAEQLPIPKLNLTGRAPPRNSTVDLNSGNIDVPPNMACWASFHNGVAAGLKIAPASRIDSSWIIYNKPKNAEQANEYAGFLMALGLSGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMAITRLLSIHIPALLPPTSTELDVPHNVQVAAVIGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLASGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLAFAMIYLKTNNRSIADWLQAPDTMYLLDFVKPEFLLLRTLARCLILWDDIMPSTEWVDSNVPQIIRENSIPLHATELPSSEDLSLETLMQAHVYIIAGACLSLGFRFAGSENKAAFNCLDKYATDFLKSLSAPTASIIGHYNLETCLSVLLLSLAMVVAGSGNLKVLQLCRFMHKKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPVHSTDNRYHLQALRHLYVLAADPRLLIPVDVDSNTPCYALIEVTFKGTQWYAETTEEMMAPTLLPELHLLKQIRVKGPRYWELLIDLSNETNHLKSILSKGGVLYVKLRAGQLSYKEDPMGWRSFSAQTITHGNEARSFKPEDISAFTSDPALLLFAEYFCKPTVNMGQKQEMLDFFSSILYECVTQEKPEMLPTYIAIDQAVRRLERGEMSETFELGQIKLVLEFFNSRCHQGRMSRNPSRGLFMNSEFLPVMKCTIDKALDQWLQAGGDACLRSYLSRQPKDESQQNMLACFLVYHSVPMPGQLAAGGLDGITNFSEMLLKFKQWNVLVRALLRLAPVLLKNPQSMVL", "length": 1948, "header": "tr|A0A8V0ZB40-1|A0A8V0ZB40_CHICK Isoform 1 of Anaphase-promoting complex subunit 1 OS=Gallus gallus OX=9031 GN=ANAPC1 PE=1 SV=1 CANONICAL=A0A8V0ZB40-1" }, "locus": { "chromosome": "3", "start_pos": 3370495, "end_pos": 3337009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043256.1", "url": "https://www.ensembl.org/id/ENSGALT00010043256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025704.1", "url": "https://www.ensembl.org/id/ENSGALP00010025704.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-GGA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-GGA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-GGA-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-GGA-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-GGA-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZW91-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "ANAPC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNVYEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEEVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKTYSSDEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSSFSHEVPPGPPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLSTDPSIVMTYDTVHGLHSVWTLRRVKTEEENVVLKFSEQGGTPQHVATSSSLTAHLRSLSKGDSPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNTREKNSQASKVFITTDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSITNIQAKDAAPVEKIDTMLVLEGCGNLVLYTGVVRVGKVFIPGLPAPSLTVSNTMPRPSTPLDSVSTPNPLSKLLGPLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEVAVQMLVKWYSVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLSSEYHRNVESHLLNKSLCLSPLEVSQTRDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGIRSLVELLVQLARDLKLEPYIDHYYRDYPTLVRTTGQVCTIDQGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESSVSDESSQYLSRISIAPQKSQAEQEENRFSFKHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNQEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQAGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPYNLETCLSAVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILAKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMRQKQEILDLFSSILYECVTQETPEMLPAYIAMDQAVRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQAGGDVCVHTYLSGQPCEESQLSMLACFLVYHSVPAPRHLPAIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8QA59-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "anapc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHVYEERATMIAAGELQSFVPFGREHCKNHPNAVNLQLRQLQPASELWSSDGAAGLVGSLQEVTLQERDKERWQLRKGTAPDDVEYDEELYVAGNMVIWSRGSKNQASCVYKAFTVDSPVQQALWCNFTVPQAKKDVKDVVEQTVCIVQSTCVNVHSMSGKDFISPLPFQVSALWPTKFGLLLERKNITVDGHMSPISREPLPTLFSMLHPLDEIAPVVCKSTGLFETRLQYVSDSALRVVFTCLKPSIIMTYDTQQCTHTVWNLRKVTSEEQNTVLKFPDQSGPAHTPNAAPSFLSTHLRNVNRLDSPASPLHCHALHNQSRIPASPALHSRVHSPSISNMAALSRAHSPGIAVPSFSGNQRFNMSCHTPSSRGHSILASPNSTLNDTLLPEMEPILPDLCIEQLWTETSAISREKGCQASKVFITSDLCENRYLCFLVESHQQLRCVKFLESNETSQLIFATVSTIAAKDAAPLEDIHTMLVLEANGSLVLYTGVTRVSKVFVPGLLSPTFSVPNQPPILSTPLENISTPARATVQHMSRLEEVGMPSPVLEMRSSLQHNESSWLEESPFQQTAPRIQTLRDPVCNRVTLELSSGSMLRITIPEVATSELVKRCLQAIRFILPKDTAMKVLVKWYNSYNAPGGPSMHLEWNLFVTCLMTMMGYNTERLTWTRNLHFEVPLSPVIAAKKARPADTGSDEDWLYLRCSDYHWQVSMRPAVSVQGLEMLFPPAGVDDQESALGLESSALLFPHIPLLFYVLHLLYEDLKLDELQRSGARALVGLLQQLARDLQLEDFIDLYWRDFPSFIKTFKEACVIDQAQMELMTWPVFLNGEAPCVFNWISRCLRGQDVAPFPYLPGICERTKLLVLSYALYVVGDEDACSTNMLKYLCRLSAGQKKNASDPFLRRQSSVKPISSSGCLAEKLVLWLTSAGFTLKDLETVPFGVALPIRDAIYQCREHPCSDWSEEVCALIGRQDLTRQAHKVTLANRKSTVGLNVMLEPPVSSEADEEEDGMTDLHPEVTALIWSQDLRVQEVRRLLQSSRPVRVNVPHLPEISDHEYIEEKENKLLQLCQRTMSLPVGRGLFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTMVDLNSGNIDVPPNMTSWPSFHNGVAAGLKIAPASQVESAWIAYNKPKSAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHSVQVAAVVGIGLVYQGTGHRHNAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRTHAGINREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSVADWLKAPDTMFLLDFIKPEFLLLRTLARCLIMWDEIFPNADWVTSNVPQIIQENIGNQDQTPVSEDLNMETLVQAHDYIIAGGCLAVGFRFAGSANSDAFDCLYKFAKNFMQCLTTSTATVTGQYNLQTCLSMVLLAVSMVMSGSGNLKVLQLCRFLHKRTFGEMNYGFHMAHHMALGLLFLGGGRYTLSTSNSAIAALLCALYPHFPAHSTDNRYHLQALRHLAVLAAEPRLLVPVDVDSLKPCYALLDVTYKETQWYEETTVELMAPTMLPELHLLKRIKVKGPRYWELNIDISKGTQHLQSILSRDGVLYVKLRAGQLPYKDDPQGWKSLLAPNLNNRSAEVRTFKPEAISTFTSDAALVSFAEHFCRASENMKHRQETVALLSAILYECVTQENPEMLPTYISIEQAVRTLERADLSETFSLWQLKLVLELCESRLARALLLSSEFLPIMKSSADRALDHWLCDNSNVLKEYLRRQTMNGDTDVNMLACFLVYHSIPSLKNMLASDLEGCSSFPELLLKSSQLGVPIRALLRLSPLLLQNHDSGV", "length": 1932 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2N0R8-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQDFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADFDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFITSQDKSEKIHKSHEVEKCICILQSSCMNMHSVDGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAMKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPDQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSGHNQSPKRHSISHSPSGSFNDSFLAPETEPIIPELCIDHLWTETLPSTREKNSPASKVFITTDLCGQKFLCFLVETQLQLRCVKFQESNDKTQLIFGSVTNVHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKIFIPGLPAPSLTMSNMMPRPSTPLDGVTTPKPLGKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLSWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSDYHHNVESHLLNKSLCLSALEISKVKEDDVSQNLSLDSSTLLFPHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYMDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGVCERSRLVVLSVALYILGDESCVSDEASQYLSKVTLNPQKPQAEQEENKFTFRHSSSVSSLAEKLVVWMTSVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSDVSSGTEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRYLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYDQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVSNRNSDVRSFKPETISSFTSDPALLSFAEYFCKPSVNMGQKQEILDLFSSILYECVAQETPEMLPAYIAMDQAIRSLRKRDMLNTSDLWQIKLILEFFSSRSHQERQQNNPKQGLFMNSEFLPVVKCTIDATLDQWLQAGGDVCVHAYLSGQPVEKSQLSMLACFLVYHSVPAPRHLPPLGLEGSTNFAELLFRFKQLKIPVRALLRLAPLLLGNPQPMVL", "length": 1944 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M801-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFIISQDKSEKIYKSHELEKCICILQSSCMNMHSIDGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEETAVLKFPEQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLPNMREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKVFIPGLPAPSLTMSNMMPRPSTPLDGVSTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAVQVLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSEYHHNVESHLLNKSLCLNALEVTKTKDEDFPQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYLDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEGTPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETSQYLSKVTLTPQKPQAEQEENRFTFRQSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSDVASGAEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGQKQEILDLFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSNTSDLWQIKLILEFFSSRSHQERQQTYPKRGLFINSEFLPVVKCTVDSTLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPLGLEGSTSFAELLFRFRHLKMPVRALLRLAPVLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53995-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "Anapc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNFSEERATMIAAGDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSTVQQALWCDFIISQDKSEKIYKSHELEKCICILQSSCMNMHSIDGKDYIASLPFQVANVWATKYGLLFERCSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPEQAGTLQNATTSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGAQRFNLSSHSQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLPNIREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIHTMLVLEGNGNLVLYTGVVRVGKVFIPGLPAPSLTMSNMMPRPSTPLDGVGTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIHSVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAIQVLVKWYNVHSAPGGPSCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDEDWEYLLNSEYHRNVESHLLNKSLCLTALEVSNAKDEDFSQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLDSYLDHYYRDSPTLVKTTGQVCTIDQGQMGFMHHPPFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETCQYLSKVTSTPQKPQAEQEENRFTFRHSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPRGKSVLSSEVSSGTEAEEEDDGMNDLNHEVMSLIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFSCLHKFAKDFMNYLSAPNASVTGPYNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGPKQEILDLFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSDTSDLWQIKLILEFFSSRSHQDRQHTYPKRGLFINSEFLPVVKCTVDATLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPMGLEGSTSFAELLYRFRHLKMPVRALLRLAPVLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54NC6-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "anapc1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVSIINLGKVKPFGLSYIINSNNNNNNNDDDDYNNEIRESESSIPYEYYFCQNPLKSCFNEEQKILLQSENDETDEKGMILVNNSFFEEAQLFWYQNTVVWSSPFTVKKKFTLPLLLSSMIYPKINNAIWSHFPFLKDLSKQQQEQQQQQHHQQSEYTTSSINNDIDDYYKYLCVLHNQGLNIYNSIGNSYQIVLPCKVINIWSSKFGLLLERDSSLDSTLLAGRDRSEIPSIFSILNPLEELKPVLTFSKSNNNNNNNNEALQQEFFSDTNQTIVFSSTDYPILITYSNIENVHIIYQVSHVKPSSNAENDNTNNNNNNNNTNTNISNNQTINNENGTTTTIINNSSIVNTSKPIFNFNNVSVNDQSFDYSNINISSSSPPFSSRNNNNNNNISNNNNTNNNTNNNNTNNSTSMMQQSIQQQQQQQQQQENSSFKFLNEDKSYFFDDESEFIIKSEIIFEEVLKDSTRLKSNTKSKSIFITLDNNQKPLLCIEINSTLFCYNLFIDQKIKSTQSSSSNKNNNNNNDRNEGIEEKLKLEFSFSISSVQSSSPIFIESFYNNNEYTIPKGINQPFIPLPTHILVLNDHLLSVYWGPFKILDLPIDNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKRKPLYIKDSTFNRVTIVYSDKEEIRFKITLGKSYLVSSCLGALSSFIPMNLLASIYQDFNDFHKFRINNLLNSNSNNNNNNNNSEEENDKEWISFQILLISLLEKSLLKRPTDADTNKKIKENNHIKKEENEDDWEFLLNSNYHKNYEKGLSFLSNLNISDSSKVYPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCNIFIESINDFNFKTSLNSFIESIDDIIIALHHQYEEFKILTFNINYIYKLSKFLIQLSLHLELFNYVDYYFRDFGDLIDFINQFKIKSKTSIDISSLKLQSLLNDDIFSIYKFVYNSFNENNSETQQQQQFNKEKFERNKLTKYHFKWIYKMKSLYSIQSKINDNNSNNKNNIKYISEKLIMKMVELDIKLEDLNSISFGLSLPLRESIKYCRSNPPIDWPLKAYSLIEREELIYKFNIDDVNNVKDGLKINSLLISGGKNKLLSNSTMNHGYNSLSTSITNTLSTASSSSNEMNSNSNITSINGQSNGLPMNSTTNQMNSHQINNNGGGGGGGDDHHHHHSNSTSFDLSKFYHGQDEFYKRITYLRFDTDQRIQEVYRLLSFSNRIQINHTQENGVSDHDYLSQLQSKLLLSVQRSISLPIACGMFTIRSIKPLPTETINIPPIILNGFVGGTKTNISLDPTMVQDNMMVWPEFHNGVAAGLKVSADQTEITNTWIIYNRPKQFNPSYSGLLMALGLQKRLSSLAFTKLFEYLASGHQLTSVGLLLGISCTKMGTMDMSIAKVLSVHIQSLHPPLSIDLDVPSYVQIAALMGIGLLYCQTSNRRMTEVLLMEIGRKPINDKPLDRDSYSLTAGMALGLVNLGKGANEGSLTDLHVEDRLRSFIGISKEDSFDHMSTFFNQSYSTPSISSNRNNNDLFNNGSNNNSSSNGGGGGGGGNNNGNNSNNGNNGSSQFKKSNTILESSKPNIDLTAPGAIIALSLIYLKTNNLKISNYLSIPDTTFGLNYIRPDLVLLRILGRNLILWDSIKPQFQWIIDSVPLVVRKNVTIDRNSEKVFQEHSNNNNNNNKSRSSSSLNDFESFILIFCNVIAGAAFSIGLKYAGSLNENAFSLLMDLIQLFRKRQVYLNKCLLKKKKIEPTFDKVMRVTTETCLNVVALSLSLVMAGSGNLETLKILRMLRSRIGNEITYGNHMAINMAIGFLFLGGGQYTLSTSNIAIASLVCSLYPRFPCSSTDNDYHLQAFRHLYFLAIDPRCLITRDVDTLAPCHVPIELTILNNDTMKLETKQLVTPCLIPELSSIRSISIKSPRYWNIFINRGFVDGGVDININNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNILKNHPTIFLKRKIGHLPYTEDPEGFRSLSKSFPKSESISLYSSSKGFQKNKEEFLKSFISDPNLLAFAKHFCTNQSNEFEHFNTTILYECLTQDTPEVIPLLLLLNDIANNFEKYSNSNTTIVLENLRIIFKFYSKWNNGYYLNNNNNKNNNNDGWLIHSTFLDSISTKIDEHFEKHFLNEQSNKKLLSNYLLTGELPNSLSTSIKRKFASFISYYNLPNNKQFQSFKSLLNNNNNNNSNAIYQLWSSLGNQINFNSINKIIELSTLSFDEDS", "length": 2269 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9H1A4-1", "protein_name": "Anaphase-promoting complex subunit 1", "gene_name": "ANAPC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGSLQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM", "length": 1944 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXV3-1", "protein_name": "Shattered", "gene_name": "shtd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIAVAEPPLEFVPRGRQTSAEHPGPHDQPMARHQLPTTEHLLLQRLQNVNISSAGEDCPSGGQESWTVRELYDDYEASEERAALRRKLTERTKRCGLQATSLPNRLLNPPLVRRVEPMCDYMVNNEEELYVNRNTVVWTQGVNDDDDTDNGVYRRMCFTTDTPVRFACFLNRSFVRGRLAQLKAAVHPDDDHLTAICVMDQDALRVYCSNGEDFLANLDFPVSQLWQTKYGLLLEKDSSNALISHMSIPMPRLFSMSHPLHEACPVVLKTATGSTGYMTEPEYTVVFTTEESDLVMLYDAKFFKHFVARLRKVTPEEINYVSQQMELGQTLMGPRSMAGNSFSSTKQTGATPKATNLSFAARNINTTTTGMGNQFGLSQSQSFSGVLGQSNRASLGTPLSQLQSSISQQSMSVKDMRKLTHVKPAKPIEPELCMEHIWTENIYGTQREFCEMATRAFIHTDLVGQTFLCYLLARSCRLQLVRLTGYGRGEVQLSTHASTLAAKDAVGLKRMHMIAVLDPSGSLLLYTGTVLISKVHITPFLAPTSIPTPLVTPMTAAPSPSASPAPSHVKTPMAAAGPASGIPSGSSSFVEVRRSSLLPTKAPGDVAAFEEELHMLSPIQPQPVSYTQRQAHNVCKSLRDPAGNRLTLVYATGRMLRIALPFLNDTRLLTRCVATLRQVLSPTQFLDFVIRWYSDRNPPGSRNYSIEQEWLLFRSTLLALMGLTAAPDVDAGENYARCATPPLHTQFGGGATATESSDGSSCSSNSTLGGQDEPKKRRIYNDCDDFTDDDWEFLLLQTTLAPCGADGHSYSVNIGALLFRMIPAIFFSLHLLYEDLKLDADFYGALPYLATFLHQLAIDMQLESYVLHYILDFPELSNRTGKLSLLGAEHGAMMLHQELLRVPAPSVFAQLEHIIVGEEEVMPYTFLECVNERSRILLQLVSLVTHGHERLNYWWQLLEIPGAVQANFTRRSKRNITADAPRSHQMLQLLLAMRLTRRDIERFPAAVHLIVAEALEEARLSPPMGCSMATYELILRPELAAHAQLPFLETSTGQPHCGRVYKEDSLSARCPPTGGSETDSPAQLRRDDMDNMDTKLLRLRFPDDMRVDEVRRLLNSSEPVVIEVQQAPGTSDHEFIEEQEKQLFALCSRTMTLPVGRGMFTLRTMLPRPSESLTMPKLCLLGKEPLKGTTIEMQQIEFPANMQMWPSFHNGVATGLKISPQAQDIDSNWIVYNKPKTHSHNALEHAGFLMALGLNGHLKTLSFMSVYKYLVKCDEMTNVGLLLGISAAHRGTMDTKTTKLLSVHLEALLPATAMELDIPQSTQVAAIMGVGLLYQGSAKRHIAEVLLQEIGRPPGPEMENSIERESYAMTAGLSLGLVTLGQGESPAGLRDLQLPDTLHYYMVGGVKRPIGGSQKEKYRLASFQVREGDTVNIDVTAPGATLALGLMFFNSGNAAIAEWMQPPDSRYLLDMVRPDFLLLRTISRGLILWQDVRPDNAWFQAQFPRALRAHLKLPFYENEYAPEDYDVDYEAISQAYCNIMAGAAFCIGLKYAGTENLVAFATLRSVIKDFLRFPSRPMGECAGRTTVESCLMVLLISISLVFAGSGNCEILRIIRFLRSRVGPQYPHITYGSHMAIHMSLGLLFLGAGRFTISQTPESIAALVCAFFPKFPIHSNDNRYHLQALRHLYVLAVEPRLFLPRDIDTNKLCLANISVLEVGATELRRLPIAPCILPVLSTLQQVVVDDENYWPVCFERSRNWDQLEKALEMSAPIDIKKRTGCLSHLEDPDRLKSMLAQTLTMEQSICWQIDMNDLQQFASERMVKQFLSRCLDTKGTDLSPPELMKRHQVMLLFYNAVVKDRMHFLPVYLTLYDHVTKSMPNNIDVWQMKLIDAYLSRSQESEHPLISVELIQMMQELFKQEMEDSTRELCLPLREFLSRRRLDPSYVTTVSGPDLQRAFCVINYYNLLPNMLNGVDLSTGTVNYMRLLYEFRRLNLGAHTIFGLMKILQSLATEVVTLDEAALLAYTMGDQ", "length": 2030 }, "evidence": [ { "id": "A0A8V0ZB40", "url": "https://omabrowser.org/oma/group/A0A8V0ZB40/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1120, "end_pos": 1122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1385, "end_pos": 1387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1583, "end_pos": 1585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1687, "end_pos": 1689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1914, "end_pos": 1916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" }, { "id": "PF18122", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18122" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1742, "end_pos": 1899, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZB40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" }, { "id": "PF12859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 206, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZB40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" }, { "id": "PF21282", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21282" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 beta-sandwich", "eco_id": "ECO_0000259", "start_pos": 1622, "end_pos": 1707, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZB40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB40" }, { "id": "PF20518", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20518" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anaphase-promoting complex subunit 1 middle", "eco_id": "ECO_0000259", "start_pos": 671, "end_pos": 986, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1111, "end_pos": 1113 }, { "start_pos": 1120, "end_pos": 1122 }, { "start_pos": 1385, "end_pos": 1387 }, { "start_pos": 1583, "end_pos": 1585 }, { "start_pos": 1687, "end_pos": 1689 }, { "start_pos": 1914, "end_pos": 1916 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 787, "end_pos": 789 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB43-1", "uniprot_ac": "A0A8V0ZB43", "uniprot_id": "A0A8V0ZB43_CHICK", "mass": { "chemical_mass": 11966.0, "monoisotopic_mass": 11966.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Proteasome assembly chaperone 3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZB43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB43", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZB43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASPVVTSKRRQEAVRGVRTEVVCTAFSNAVLVVVTQYGKMGTLVYVDPDTVGDNVGRPSLSTKVLLGKDEVGAAARRRGTEGRGSAVGGAVRAARGPARESPPLSGVCAAVKWV", "length": 116, "header": "tr|A0A8V0ZB43-1|A0A8V0ZB43_CHICK Isoform 1 of Proteasome assembly chaperone 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZB43-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43/entry#A0A8V0ZB43-1", "sequence": { "sequence": "MAASPVVTSKRRQEAVRGVRTEVVCTAFSNAVLVVVTQYGKMGTLVYVDPDTVGDNVGRPSLSTKVLLGKDEVGAAARRRGTEGRGSAVGGAVRAARGPARESPPLSGVCAAVKWV", "length": 116, "header": "tr|A0A8V0ZB43-1|A0A8V0ZB43_CHICK Isoform 1 of Proteasome assembly chaperone 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZB43-1" }, "locus": { "chromosome": "14", "start_pos": 2627616, "end_pos": 2627269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047526.1", "url": "https://www.ensembl.org/id/ENSGALT00010047526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028138.1", "url": "https://www.ensembl.org/id/ENSGALP00010028138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome assembly", "id": "GO:0043248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043248", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB45-1", "uniprot_ac": "A0A8V0ZB45", "uniprot_id": "A0A8V0ZB45_CHICK", "mass": { "chemical_mass": 57964.0, "monoisotopic_mass": 57964.0 }, "refseq": { "ac": "NP_001376440", "name": "probable G-protein coupled receptor 75", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376440" }, "gene_names": [ { "name": "GPR75", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" } ] }, { "name": "GPR75", "type": "synonym", "evidence": [ { "id": "NP_001376440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376440" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 75", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 75", "type": "synonym", "evidence": [ { "id": "NP_001376440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376440" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: SRR13267656.4944.1, SRR13267648.2765.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000060.1. On Dec 3, 2021 this sequence version replaced NP_001376440.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376440" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45", "locus": { "chromosome": "3", "start_pos": 3197731, "end_pos": 3194484, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019388", "url": "https://www.ensembl.org/id/ENSGALG00010019388" } ] } } ], "crossref": [ { "id": "A0A8V0ZB45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB45", "database": "AlphaFoldDB", "categories": [] }, { "id": "428544", "url": "https://www.ncbi.nlm.nih.gov/gene/428544", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PFMGAPV", "url": "https://omabrowser.org/oma/group/PFMGAPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB45", "url": "https://www.orthodb.org/?gene=A0A8V0ZB45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24228:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24228:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNASGRLPAGGEEEPPSAALLPLGGNGSAAAGLREGTHTATLAACASLLALVFCLGSYGNLIVFLSFFDPALRKFRTNFDFMILNLSFCDLFICGVAAPMFAFVLFFDSARGVPGAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPHRAAPFPCTLLLTLLLWATSFTLATMATLRTHGSRLCLPMSSFARGDGKVILYLYVTDFICCVAVVSVSYVMIAQALRRNAQVRKCPPAVAVDASRPQPFVGPTAASAGQSALPALYRNQGSGKLQHSQAHGYTTHLGQPPAASRLQLVSAVNLSTTKDSRAVVTCVIIVLSVLVCCLPLGISLVQDMLSGSGGFVLYQFELCGFTLIFFKSGLNPFIYSRNSAGLRRRALWCLQYLSLVFFCCKQKTRLQAMGKGSLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESVLSPKASYGHQHYGQSTSTPMNTRIEPYYSIYNSSPSQEASTPNSLQPVNSTFGFTKSYIAMHYHTTTDLVRDYDSTSAKPIPVPSV", "length": 536, "header": "tr|A0A8V0ZB45-1|A0A8V0ZB45_CHICK Isoform 1 of G protein-coupled receptor 75 OS=Gallus gallus OX=9031 GN=GPR75 PE=4 SV=1 CANONICAL=A0A8V0ZB45-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45/entry#A0A8V0ZB45-1", "sequence": { "sequence": "MNASGRLPAGGEEEPPSAALLPLGGNGSAAAGLREGTHTATLAACASLLALVFCLGSYGNLIVFLSFFDPALRKFRTNFDFMILNLSFCDLFICGVAAPMFAFVLFFDSARGVPGAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPHRAAPFPCTLLLTLLLWATSFTLATMATLRTHGSRLCLPMSSFARGDGKVILYLYVTDFICCVAVVSVSYVMIAQALRRNAQVRKCPPAVAVDASRPQPFVGPTAASAGQSALPALYRNQGSGKLQHSQAHGYTTHLGQPPAASRLQLVSAVNLSTTKDSRAVVTCVIIVLSVLVCCLPLGISLVQDMLSGSGGFVLYQFELCGFTLIFFKSGLNPFIYSRNSAGLRRRALWCLQYLSLVFFCCKQKTRLQAMGKGSLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESVLSPKASYGHQHYGQSTSTPMNTRIEPYYSIYNSSPSQEASTPNSLQPVNSTFGFTKSYIAMHYHTTTDLVRDYDSTSAKPIPVPSV", "length": 536, "header": "tr|A0A8V0ZB45-1|A0A8V0ZB45_CHICK Isoform 1 of G protein-coupled receptor 75 OS=Gallus gallus OX=9031 GN=GPR75 PE=4 SV=1 CANONICAL=A0A8V0ZB45-1" }, "locus": { "chromosome": "3", "start_pos": 3196131, "end_pos": 3194524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046871.1", "url": "https://www.ensembl.org/id/ENSGALT00010046871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027885.1", "url": "https://www.ensembl.org/id/ENSGALP00010027885.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IPI9-1", "protein_name": "Probable G-protein coupled receptor 75", "gene_name": "gpr75", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCTMNSTAWPLDLAEFAKPRGFNSSQSQSASAGGWALIHTATLASCSLLLVLIFCLGSYGNLVVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICCVTAPMFALVLFLDAGDNNGGVSKGFCFAFHLTSSGFIIMSLETVAVIALHRLRMVLGQQPNRTASFPCTLALTALLWTSSFTLAALVTLRAYPRSSGPCLPHFGLTGNKAKVVLYVYIADFAFCVGVVSISYLMIAQALRKNAQVRKCPIITVDATRPPASHPPLIAAGFEGMQCTVQVPSLYRNQTYNKLQHVQTHSFTRRTNQPLVPGAATGATCCQLVTSVNLATAKDSKAVVTCVVIVISVLLCCLPLGISLAQDMVSPESSFVHYQFELCGFALIFLKSGINPFVYSRNSAGLRRRVLCCLQWLTLGFLCCKHKTRLHAMGKGSLEVNRNKSSHHETNSAYMLSPKPQRRLVDQACGPSHSRDSMPSPCATAGRKPRPPSTSTPINTRIEPYYSIYNSSPSAGPSSPNSLQPVNSQTTPFAKSYVAMHYHIHQETLQDFDSTSAHQIPIPSV", "length": 553 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287AG85-1", "protein_name": "G protein-coupled receptor 75", "gene_name": "GPR75", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSTDHLQDASNTTLLHVPRSQGGNSTVLQGDLQDLIHTATLVTCTFLLAIIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICCVTAPMFTFVLFFSSASGIPDAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPNRTASFPCTLLLTLLLWATSFTLATLATLKTSKSHLCLPMSSLIAREGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAHVRKCPPVITVDASRPQPFMGASGKGGGDPIQCTMPALYRNQNYNKLQHVQTHGYTKSPNQLPTPVASRLQLVSAVNLSTAKDSKAVVTCVIIVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLQYIGLSFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESVVSPRMSAGQQHYGQSSSTPINTRIEPYYSIYNSSPSQEESIPHNLQPVNSFGFATSYIAMHYHTTNDLMQEYDSTSAKQIPVPSV", "length": 540 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z826-1", "protein_name": "G protein-coupled receptor 75", "gene_name": "Gpr75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSSAPLQNVPNATLLYTPPLQGGNNTSLQEGLRDFIHTATLVTCTVLLAIIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICGATAPMFTFVLFFSSARSIPDSFCFTFHLTSSGFIIMSLKMVAVIALHRLRMVMGKQPNCTASFSCILLLTLLLWATSFTLATLATLRTSKSHLCLPMSSLMDGEGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVKKCPPVITVDASRPQPFMGASVKGNGDPIQCTMPALYRNQNYNKLQHNQTHGYTKNANQMPIPSASRLQLVSAVNLSTAKDSKAVVTCMVIVLSVLVCCLPLGISLLQVVLSDSGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLRYTGLGFLCCKQKTRLRAMGKGNLEINRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESVASPKVSAGHHPCGQSSSTPINTRIEPYYSIYNSSPSQQESSPANLQPVNSFGFASSYIAMHYYTTNDLMQDYDSTSAKQIPIPSV", "length": 540 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MG76-1", "protein_name": "G protein-coupled receptor 75", "gene_name": "GPR75", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSTGHLQDVPNTTLLHVPHAQGGNSTSIQEGLQEPVHTATLVTCTFLLAVIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASGIPDTFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPNRTASFPCTLLLTLLLWTTSFTLATLATLKTSKSHLCLPMSSLIAGEGKAILSLYVVDFTFCVAVVFVSYVMIAQTLRKNAQVRKCPAVITVDASRPQPFMGAPVKGGGEPIQCTMPALYRNQNYNKLQHVQTHGYTKSPNQLPTPAASRLQLVSAVNLSTAQDSRAVVTCVIIVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELLGFTLIFLKSGLNPFIYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESVVSPKMSAGHQHYGQSSSTPINTRIEPYYSIYNSSPSQEESIPHNLQPVNSFGFANSYIAMHYHTTNDLMQEYDSTSAKQIPVPSV", "length": 540 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95800-1", "protein_name": "Probable G protein-coupled receptor 75", "gene_name": "GPR75", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSTGHLQDAPNATSLHVPHSQEGNSTSLQEGLQDLIHTATLVTCTFLLAVIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASSIPDAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPNRTASFPCTVLLTLLLWATSFTLATLATLKTSKSHLCLPMSSLIAGKGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVRKCPPVITVDASRPQPFMGVPVQGGGDPIQCAMPALYRNQNYNKLQHVQTRGYTKSPNQLVTPAASRLQLVSAINLSTAKDSKAVVTCVIIVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESMVSPKISAGHQHCGQSSSTPINTRIEPYYSIYNSSPSQEESSPCNLQPVNSFGFANSYIAMHYHTTNDLVQEYDSTSAKQIPVPSV", "length": 540 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6X632-1", "protein_name": "Probable G protein-coupled receptor 75", "gene_name": "Gpr75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSAPLQNVPNATLLNMPPLHGGNSTSLQEGLRDFIHTATLVTCTFLLAIIFCLGSYGNFIVFLSFFDPSFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASSIPDSFCFTFHLTSSGFVIMSLKMVAVIALHRLRMVMGKQPNCTASFSCILLLTLLLWATSFTLATLATLRTNKSHLCLPMSSLMDGEGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVKKCPPVITVDASRPQPFMGASVKGNGDPIQCTMPALYRNQNYNKLQHSQTHGYTKNINQMPIPSASRLQLVSAINFSTAKDSKAVVTCVVIVLSVLVCCLPLGISLVQMVLSDNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLRYTGLGFLCCKQKTRLRAMGKGNLEINRNKSSHHETNSAYMLSPKPQRKFVDQACGPSHSKESAASPKVSAGHQPCGQSSSTPINTRIEPYYSIYNSSPSQQESGPANLPPVNSFGFASSYIAMHYYTTNDLMQEYDSTSAKQIPIPSV", "length": 540 }, "evidence": [ { "id": "A0A8V0ZB45", "url": "https://omabrowser.org/oma/group/A0A8V0ZB45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "C-C chemokine receptor activity", "id": "GO:0016493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016493", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB45" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 371, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB47-1", "uniprot_ac": "A0A8V0ZB47", "uniprot_id": "A0A8V0ZB47_CHICK", "mass": { "chemical_mass": 38904.0, "monoisotopic_mass": 38904.0 }, "refseq": {}, "gene_names": [ { "name": "HAUS2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47" } ] } ], "protein_names": [ { "name": "HAUS augmin like complex subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAUS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47", "locus": { "chromosome": "5", "start_pos": 25261968, "end_pos": 25256834, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019693", "url": "https://www.ensembl.org/id/ENSGALG00010019693" } ] } } ], "crossref": [ { "id": "A0A8V0ZB47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB47", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB47", "url": "https://www.orthodb.org/?gene=A0A8V0ZB47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBU6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16039:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16039:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZB47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RSSRRHSPHRATGRSTARPQKRRGEPRRSHVPIPTKSGGRRGSRRNRLRPRFPPPFETRSAGSPHGSSGSGTCQPAVTPAVAAARRPPFRVAQDGGAPPLGFLSNGALQPRAPPKGTAGLRRAEAASAAERRPGRLRPLGVGRAHGDRGRAGEKNSFAQRDSLTETLDLACEEFECFARFSEREKMANIRAEINEKKLETELLQLEMETADIVHPFYLSKKYQILQDVNRHLEAVLKEKKRLRQRLIKPICQETLPIKADFHKYVVELLTEAVTFIEKLENHLQTVRVIPQVPTFMKNLDVALTKTEVLVTDLEELTEQIVQWREVQKEVYSDSICNTAELDLGLSA", "length": 347, "header": "tr|A0A8V0ZB47-1|A0A8V0ZB47_CHICK Isoform 1 of HAUS augmin like complex subunit 2 OS=Gallus gallus OX=9031 GN=HAUS2 PE=4 SV=1 CANONICAL=A0A8V0ZB47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB47/entry#A0A8V0ZB47-1", "sequence": { "sequence": "RSSRRHSPHRATGRSTARPQKRRGEPRRSHVPIPTKSGGRRGSRRNRLRPRFPPPFETRSAGSPHGSSGSGTCQPAVTPAVAAARRPPFRVAQDGGAPPLGFLSNGALQPRAPPKGTAGLRRAEAASAAERRPGRLRPLGVGRAHGDRGRAGEKNSFAQRDSLTETLDLACEEFECFARFSEREKMANIRAEINEKKLETELLQLEMETADIVHPFYLSKKYQILQDVNRHLEAVLKEKKRLRQRLIKPICQETLPIKADFHKYVVELLTEAVTFIEKLENHLQTVRVIPQVPTFMKNLDVALTKTEVLVTDLEELTEQIVQWREVQKEVYSDSICNTAELDLGLSA", "length": 347, "header": "tr|A0A8V0ZB47-1|A0A8V0ZB47_CHICK Isoform 1 of HAUS augmin like complex subunit 2 OS=Gallus gallus OX=9031 GN=HAUS2 PE=4 SV=1 CANONICAL=A0A8V0ZB47-1" }, "locus": { "chromosome": "5", "start_pos": 25261565, "end_pos": 25257033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047533.1", "url": "https://www.ensembl.org/id/ENSGALT00010047533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028143.1", "url": "https://www.ensembl.org/id/ENSGALP00010028143.1" } ] } }, { "isoform_ac": "A0A8V0ZBU6-1", "url": 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"id": "A0A8V0ZB68", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB68", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB68", "url": "https://www.orthodb.org/?gene=A0A8V0ZB68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12277:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12277:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZB68/entry#A0A8V0ZB68-1", "sequence": { "sequence": "MCPALPAHSCPRGRLWGTGWCPPVMLNHSSEGSAPSPKPKLGEHSHKSATEKTKPTGWLGWCPRLHTVLLQLLLIYISVPFLIRLFPVILTKFVFLNFLAFPFFADLRQPALLLNNTISLYLPTEPGVTVGIWHTVPGSSGNEARGREQRWFEEALADAHPIIIYLHGNGGTRAARHRIQFMKLMGAAGFHILALDYRGYGDSSGQPSESGFTTDVLALYDWAKARSGNSSIIFWGHSLGTGIATNAARKLQEERGVQVDAVVLESPYTNIRDAAANIPITKIYRQFPGFEYLILDSMALGNMFFRNDENVKVLACPLLILHAEDDTVLPPRLGRQLFETARRAYKDKSKVKFITFPGKLGLGHDYISSNPELPTLVKDFLNMK", "length": 384, "header": "tr|A0A8V0ZB68-1|A0A8V0ZB68_CHICK Isoform 1 of Abhydrolase domain containing 12B OS=Gallus gallus OX=9031 GN=ABHD12B PE=1 SV=1 CANONICAL=A0A8V0ZB68-1" }, "locus": { "chromosome": "5", "start_pos": 57728057, "end_pos": 57724584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046947.1", "url": "https://www.ensembl.org/id/ENSGALT00010046947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027910.1", "url": "https://www.ensembl.org/id/ENSGALP00010027910.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB68" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB68" } ], "pmid": "" }, { "name": "phosphatidylcholine lysophospholipase activity", "id": "GO:0004622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004622", 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"MRLASLKMKTACCEDCLFQASCPAPYSLPGVSILIFNTSRQCFVVVKQFRPAVYMCEVERQHPQLFQNQDKESFSRLEDPLPAVVGVTYELCAGIVDKPHLSLEEIACEEILEECGYRVPVTNLKKITSYRWRLGLASKQQTCRIFIYIRKQRSGVGVTGSRQTLFYAEVTDQMKTSGGGGQPEEGELIEVVEIPLEDSMKFAYDETLPKTMGVIFSFTWFQNNIAPKLPKSNIKAP", "length": 237, "header": "tr|A0A8V0ZB74-1|A0A8V0ZB74_CHICK Isoform 1 of Nudix hydrolase 14 OS=Gallus gallus OX=9031 GN=NUDT14 PE=1 SV=1 CANONICAL=A0A8V0ZB74-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74/entry#A0A8V0ZB74-1", "sequence": { "sequence": "MRLASLKMKTACCEDCLFQASCPAPYSLPGVSILIFNTSRQCFVVVKQFRPAVYMCEVERQHPQLFQNQDKESFSRLEDPLPAVVGVTYELCAGIVDKPHLSLEEIACEEILEECGYRVPVTNLKKITSYRWRLGLASKQQTCRIFIYIRKQRSGVGVTGSRQTLFYAEVTDQMKTSGGGGQPEEGELIEVVEIPLEDSMKFAYDETLPKTMGVIFSFTWFQNNIAPKLPKSNIKAP", "length": 237, "header": "tr|A0A8V0ZB74-1|A0A8V0ZB74_CHICK Isoform 1 of Nudix hydrolase 14 OS=Gallus gallus OX=9031 GN=NUDT14 PE=1 SV=1 CANONICAL=A0A8V0ZB74-1" }, "locus": { "chromosome": "5", "start_pos": 51741329, "end_pos": 51721501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047593.1", "url": "https://www.ensembl.org/id/ENSGALT00010047593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028173.1", "url": "https://www.ensembl.org/id/ENSGALP00010028173.1" } ] } }, { "isoform_ac": "A0A8V0ZBX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74/entry#A0A8V0ZBX1-1", "sequence": { "sequence": "MRLASLKMKTACCEDCLFQASCPAPYSLPGVSILIFNTSRQCFVVVKQFRPAVYMCEVERQHPQLFQNQDKESFSRLEDPLPAVVGVTYELCAGIVDKPHLSLEEIACEEILEECGYRVPVTNLKKITSYRSGVGVTGSRQTLFYAEVTDQMKTSGGGGQPEEGELIEVVEIPLEDSMKFAYDETLPKTMGVIFSFTWFQNNIAPKLPKSNIKAP", "length": 215, "header": "tr|A0A8V0ZBX1-1|A0A8V0ZBX1_CHICK Computationally mapped isoform of Uridine diphosphate glucose pyrophosphatase NUDT14 OS=Gallus gallus OX=9031 GN=NUDT14 PE=1 SV=1 CANONICAL=A0A8V0ZB74-1" }, "locus": { "chromosome": "5", "start_pos": 51741329, "end_pos": 51721501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047607.1", "url": "https://www.ensembl.org/id/ENSGALT00010047607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028177.1", "url": "https://www.ensembl.org/id/ENSGALP00010028177.1" } ] } }, { "isoform_ac": "A0A8V0ZHV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74/entry#A0A8V0ZHV8-1", "sequence": { "sequence": "MMKTACCEDCLFQASCPAPYSLPGVSILIFNTSRQCFVVVKQFRPAVYMCEVERQHPQLFQNQDKESFSRLEDPLPAVVGVTYELCAGIVDKPHLSLEEIACEEILEECGYRVPVTNLKKITSYRSGVGVTGSRQTLFYAEVTDQMKTSGGGGQPEEGELIEVVEIPLEDSMKFAYDETLPKTMGVIFSFTWFQNNIAPKLPKSNIKAP", "length": 209, "header": "tr|A0A8V0ZHV8-1|A0A8V0ZHV8_CHICK Computationally mapped isoform of Uridine diphosphate glucose pyrophosphatase NUDT14 OS=Gallus gallus OX=9031 GN=NUDT14 PE=1 SV=1 CANONICAL=A0A8V0ZB74-1" }, "locus": { "chromosome": "5", "start_pos": 51740221, "end_pos": 51721501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047586.1", "url": "https://www.ensembl.org/id/ENSGALT00010047586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028170.1", "url": "https://www.ensembl.org/id/ENSGALP00010028170.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-480985", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-480985", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate-glucose" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "UDP-sugar diphosphatase activity", "id": "GO:0008768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" }, { "name": "ADP-ribose diphosphatase activity", "id": "GO:0047631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribose phosphate metabolic process", "id": "GO:0019693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" }, { "name": "nucleoside phosphate metabolic process", "id": "GO:0006753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006753", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB74" }, { "id": "PS51462", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nudix hydrolase", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 216, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.45", "ec_name": "UDP-sugar + H2O = UMP + alpha-D-aldose 1-phosphate.", "evidence": [ { "id": "3.6.1.45", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.45" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZB76-1", "uniprot_ac": "A0A8V0ZB76", "uniprot_id": "A0A8V0ZB76_CHICK", "mass": { "chemical_mass": 113121.0, "monoisotopic_mass": 113121.0 }, "refseq": { "ac": "XP_015143772", "name": "zinc finger MIZ domain-containing protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143772" }, "gene_names": [ { "name": "ZMIZ1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZB76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76" } ] }, { "name": "ZMIZ1", "type": "synonym", "evidence": [ { "id": "XP_015143772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143772" } ] } ], "protein_names": [ { "name": "Zinc finger MIZ-type containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZB76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MIZ domain-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015143772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143772" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143772.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143772" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZB76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76", "locus": { "chromosome": "6", "start_pos": 13045083, "end_pos": 13366979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019977", "url": "https://www.ensembl.org/id/ENSGALG00010019977" } ] } } ], "crossref": [ { "id": "A0A8V0ZB76", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZB76", "database": "AlphaFoldDB", "categories": [] }, { "id": "423724", "url": "https://www.ncbi.nlm.nih.gov/gene/423724", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB76", "url": "https://www.orthodb.org/?gene=A0A8V0ZB76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25527", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25527", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143772", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSMDRHIQQTNDRLQCIKQHLQNPANFHNAATELLDWCGDPRAFQRPFEQSLMGCLTVVSRVAAQQGFDLDLGYRLLAVCAANRDKFTPKSAALLSSWCEELGRLLLLRHQKSRQNDPPGKLPMQPPMNSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGINSPQFSGQQQQFSAKAGSTQPYIQQGMYGRPNYPGSGGFGGSYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDMNQYGPVCSSFQMGPTQAYNNQFMNQPGPRGPASMPGNMNPASMGAGMTPSSMSGPPMGMNQPRPPGMSPFSTHGQRMPQQAYPGPRPQSLPIQGIKRPYPGEPNYGNQQYGPNSQFPNQPGQYPTPNPPRPLTSPNYPGQRMPSQQNTGQYPPPTVNMGQYYKPSRPVPVANYPHSPVPGNPTPPMTPGSNIPPYLSPNQDVKPPFPPDIKPNINALPPPPTNHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNATLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQNSEFEEVTIDPTCSWRPVPIKSDIHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPSLPPPPGGNNSTEYGNQGNSYQGHGNFDFPHGNPGGTSMNDFMHGPQLSHPPDMPSSMAALDKPLSHPMQESIPHPGSTDQSHTSMQQGLHVPHPSSQSGQPLHHSGPPSQQSRQPPPAASGNHPHSDLTFNPSSALEGQAGGQGAPDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN", "length": 1043, "header": "tr|A0A8V0ZB76-1|A0A8V0ZB76_CHICK Isoform 1 of Zinc finger MIZ-type containing 1 OS=Gallus gallus OX=9031 GN=ZMIZ1 PE=4 SV=1 CANONICAL=A0A8V0ZB76-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB76/entry#A0A8V0ZB76-1", "sequence": { "sequence": "MNSMDRHIQQTNDRLQCIKQHLQNPANFHNAATELLDWCGDPRAFQRPFEQSLMGCLTVVSRVAAQQGFDLDLGYRLLAVCAANRDKFTPKSAALLSSWCEELGRLLLLRHQKSRQNDPPGKLPMQPPMNSMSSMKPTLSHSDGSFPYDSVPWQQNTNQPPGSLSVVTTVWGVTNTSQSQVLGNPMANANNPMNPGGNPMASGMTTSNPGINSPQFSGQQQQFSAKAGSTQPYIQQGMYGRPNYPGSGGFGGSYPGGPNAPAGMGIPPHTRPPADFTQPAAAAAAAAVAAAAATATATATATVAALQETQNKDMNQYGPVCSSFQMGPTQAYNNQFMNQPGPRGPASMPGNMNPASMGAGMTPSSMSGPPMGMNQPRPPGMSPFSTHGQRMPQQAYPGPRPQSLPIQGIKRPYPGEPNYGNQQYGPNSQFPNQPGQYPTPNPPRPLTSPNYPGQRMPSQQNTGQYPPPTVNMGQYYKPSRPVPVANYPHSPVPGNPTPPMTPGSNIPPYLSPNQDVKPPFPPDIKPNINALPPPPTNHNDELRLTFPVRDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSVAASSGNATLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMWGILNAIQNSEFEEVTIDPTCSWRPVPIKSDIHIKDDPDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPSLPPPPGGNNSTEYGNQGNSYQGHGNFDFPHGNPGGTSMNDFMHGPQLSHPPDMPSSMAALDKPLSHPMQESIPHPGSTDQSHTSMQQGLHVPHPSSQSGQPLHHSGPPSQQSRQPPPAASGNHPHSDLTFNPSSALEGQAGGQGAPDMPEPSLDLLPELTNPDELLSYLDPPDLPSNSNDDLLSLFENN", 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"tr|F1NR18-1|A0A8V0ZBB7_CHICK Computationally mapped isoform of Beta-tectorin OS=Gallus gallus OX=9031 GN=TECTB PE=4 SV=1 CANONICAL=A0A8V0ZBB7-1" }, "locus": { "chromosome": "6", "start_pos": 27476603, "end_pos": 27469639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047713.1", "url": "https://www.ensembl.org/id/ENSGALT00010047713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028220.1", "url": "https://www.ensembl.org/id/ENSGALP00010028220.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396320", "resource": "KEGG Pathway" }, { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AC15-1", "protein_name": "Beta-tectorin", "gene_name": "Tectb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVARAFVLLALFAEASAKSCTPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDSTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQSPYAKFSPLFRVATVHVKNGSMGTFESQLSLNFYTNAKFSTKKEAPFVLETSEIGSDLFAGVEAKGLSVRFKVVLNSCWATPSADFMYPLQWQLINKGCSTDETVLVHENGKDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVNCDKRKRMLRDQTGGVLVVELSLRSRGFSGLCDFSDVLLHLVLMLGTWAVL", "length": 339 }, "evidence": [ { "id": "A0A8V0ZBB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08524-1", "protein_name": "Beta-tectorin", "gene_name": "Tectb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVRAFVLLALFAEASAKSCTPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDSTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFYTNAKFSTKKEAPFVLETSEIGSDLFAGVEAKGLSVRFKVVLNSCWATPSADFMYPLQWQLINKGCPTDETVLVHENGKDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVNCDKRKRMLRDQTGGVLVVELSLRSRAFSGLCDFSDVLLHLILMLGTWAVL", "length": 329 }, "evidence": [ { "id": "A0A8V0ZBB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PL2-1", "protein_name": "Beta-tectorin", "gene_name": "TECTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVTKAFVLLAIFAEASAKSCAPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDTTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFYTNAKFSIKKEAPFVLEASEIGSDLFAGVEAKGLSIRFKVVLNSCWATPSADFMYPLQWQLINKGCPTDETVLVHENGRDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVTCDKRKRLLRDQTGGVLVVELSLRSRGFSSLYSFSDVLHHLIMMLGICAVL", "length": 329 }, "evidence": [ { "id": "A0A8V0ZBB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB7" }, { "id": "PS51034", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 287, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 207 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBC4-1", "uniprot_ac": "A0A8V0ZBC4", "uniprot_id": "A0A8V0ZBC4_CHICK", "mass": { "chemical_mass": 87994.0, "monoisotopic_mass": 87994.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107050638", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4" } ] } ], "protein_names": [ { "name": "Sorbin and SH3 domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107050638", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11781", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11781", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBC0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBC4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC79", "url": "https://www.orthodb.org/?gene=A0A8V0ZC79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPHWGHPWDPMRVAQGPLWDPNVGCVGSSTGPPFRSTYGTPLGDVRNHPWDPIRVAQGPPWDPTGGCPGSPMRPLWGPPWDPNGGRPGSSMGPPLGAPMGPPLGDVQNHPWDPHRGHPWAPISVAQSPPWDPTGGCPGPPMRPLWGHPWDPNGGCVGSSMGPPLGAPLGPQWGTSRNTPGTPIGDTPGPPLALLRAPRGTPLGTSRAAHGTLPLLTHSPRAERTLSPHDPPEAPITPPAPPPGPMEGAVPPPGCSAISGGGGARRERRWVKYDGIGPVDETGLPLASRSSVDRPRDWYRCMFQQIHCRLPEPEWDAQCCATAQPRSEPPAAPPALPNGTERTPWGDGGDTAEPGSVFAYEPGALNGAPHRGAGCAHRDPISPPQPPGAVPAVPPIEVQLQRELEQLSAELDEDIRAMERPQRMAAARLKFDFRAESPRELSLRRGDVVLRLRAVDSNWLQGEHRGRVGIFPRTYVELLPPGETPRPRWGTPTAPHGCATAAFSFRGELPVELSCRRGERLSLLRRVDAHWYEGCVVGTAQRGIVPRCYLRVHREPGGGPTAPQPTAPQPTAPQPTAPQHTAPQHAAPQPPTLQPPTPQPKTPQPPTPQPPTPQPPTLQPRAPQPPTPQPPTPQLPTLQPPTPQPTAPQHTAPQHTAPQPRAPQPPTPQPPTPQLPTLQPPTPQPPTPQPPAPHMAAEQGRGDPAVHPPSPRHWDFTPCPAPLLPHSRPTAANPTAGPREQPPPAGGPLPRPAPTSPHLGSETRWTPYRALYDYRPQNGDELELRDGDRLDVLQCCDDGWFVGVSQRTQKFGTFPGNYVAPL", "length": 822, "header": "tr|A0A8V0ZBC4-1|A0A8V0ZBC4_CHICK Isoform 1 of Sorbin and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=LOC107050638 PE=4 SV=1 CANONICAL=A0A8V0ZBC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4/entry#A0A8V0ZBC0-1", "sequence": { "sequence": "MGPHWGHPWDPMRVAQGPLWDPNVGCVGSSTGPPFRSTYGTPLGDVRNHPWDPIRVAQGPPWDPTGGCPGSPMRPLWGPPWDPNGGRPGSSMGPPLGAPMGPPLGDVQNHPWDPHRGHPWAPISVAQSPPWDPTGGCPGPPMRPLWGHPWDPNGGCVGSSMGPPLGAPLGPQWGTSRNTPGTPIGDTPGPPLALLRAPRGTPLGTSRAAHGTLPLLTHSPRAERTLSPHDPPEAPITPPAPPPGPMEGAVPPPGCSAISGGGGARRERRWVKYDGIGPVDETGLPLASRSSVDRPRDWYRCMFQQIHCRLPEPEWDAQCCATGAAAAGIGAAECRTG", "length": 337, "header": "tr|A0A8V0ZBC0-1|A0A8V0ZBC4_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=LOC107050638 PE=4 SV=1 CANONICAL=A0A8V0ZBC4-1" }, "locus": { "chromosome": "22", "start_pos": 1478497, "end_pos": 1474618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048317.1", "url": "https://www.ensembl.org/id/ENSGALT00010048317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028489.1", "url": "https://www.ensembl.org/id/ENSGALP00010028489.1" } ] } }, { "isoform_ac": "A0A8V0ZBC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4/entry#A0A8V0ZBC4-1", "sequence": { "sequence": "MGPHWGHPWDPMRVAQGPLWDPNVGCVGSSTGPPFRSTYGTPLGDVRNHPWDPIRVAQGPPWDPTGGCPGSPMRPLWGPPWDPNGGRPGSSMGPPLGAPMGPPLGDVQNHPWDPHRGHPWAPISVAQSPPWDPTGGCPGPPMRPLWGHPWDPNGGCVGSSMGPPLGAPLGPQWGTSRNTPGTPIGDTPGPPLALLRAPRGTPLGTSRAAHGTLPLLTHSPRAERTLSPHDPPEAPITPPAPPPGPMEGAVPPPGCSAISGGGGARRERRWVKYDGIGPVDETGLPLASRSSVDRPRDWYRCMFQQIHCRLPEPEWDAQCCATAQPRSEPPAAPPALPNGTERTPWGDGGDTAEPGSVFAYEPGALNGAPHRGAGCAHRDPISPPQPPGAVPAVPPIEVQLQRELEQLSAELDEDIRAMERPQRMAAARLKFDFRAESPRELSLRRGDVVLRLRAVDSNWLQGEHRGRVGIFPRTYVELLPPGETPRPRWGTPTAPHGCATAAFSFRGELPVELSCRRGERLSLLRRVDAHWYEGCVVGTAQRGIVPRCYLRVHREPGGGPTAPQPTAPQPTAPQPTAPQHTAPQHAAPQPPTLQPPTPQPKTPQPPTPQPPTPQPPTLQPRAPQPPTPQPPTPQLPTLQPPTPQPTAPQHTAPQHTAPQPRAPQPPTPQPPTPQLPTLQPPTPQPPTPQPPAPHMAAEQGRGDPAVHPPSPRHWDFTPCPAPLLPHSRPTAANPTAGPREQPPPAGGPLPRPAPTSPHLGSETRWTPYRALYDYRPQNGDELELRDGDRLDVLQCCDDGWFVGVSQRTQKFGTFPGNYVAPL", "length": 822, "header": "tr|A0A8V0ZBC4-1|A0A8V0ZBC4_CHICK Isoform 1 of Sorbin and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=LOC107050638 PE=4 SV=1 CANONICAL=A0A8V0ZBC4-1" }, "locus": { "chromosome": "22", "start_pos": 1478497, "end_pos": 1465547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048324.1", "url": "https://www.ensembl.org/id/ENSGALT00010048324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028494.1", "url": "https://www.ensembl.org/id/ENSGALP00010028494.1" } ] } }, { "isoform_ac": "A0A8V0ZC79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC4/entry#A0A8V0ZC79-1", "sequence": { "sequence": 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Peptide", "id": "ENSGALP00010025798.1", "url": "https://www.ensembl.org/id/ENSGALP00010025798.1" } ] } }, { "isoform_ac": "A0A8V0ZBD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBD0/entry#A0A8V0ZBD0-1", "sequence": { "sequence": "MLGEKKQLPVRRELYTDPAFPASDTSIFFDSCTPLAQFRGEISWLRPQDICSTPRLFSNSLQDVQVKQGILGDCWFLCACVALQKSKYLLNKVFPPGQPSWADELYQGRFTCHVWQFGHWVEVTIDDRLPCLGGKLCFSQCQTEDLFWLPLLEKAYAKVHGSYEQLWAGQVADALVDLTGGIAERWALKDPARNTGKEKSGMVLKKEVFRRLMVLKEQCVISCSVLNSRQGASELGEFHAFIVTDMLNLSEVSGKEIILLRIRNPWGRRCWRGPWCEGGEGWSQLDPVVASELLSQIQEGEFWVDEEEFFREFDEITVGFPVNEEGQLQSLYTEKVLYHSQNLFGSWVRGQSAGGCRNNSSFPTNPKFWLRVCEKSEVCIALLQKHRKYSADWAGRIKNLTRLVEENLSLAEGIQGKKYQAVGLHVWKVEKKRFNLPKTLSAPPVVGTVCHSYDREVHVCCDLSPGYYLVVPSTFLKDAVGHFLLRVFSTGRISLSEIKPPPPDAALTEELPVGPGKSSVKITLRQHCQDSKCRPIGFHIFQVPNSSWKPNTSSFLHLEPLVSCVPHCYSQEVSRLCRLPAGSYVIIPSTYLPNTEGSFTVIIATKIDRKRIHSRETLGQVLQEVSFTTVMKK", "length": 633, "header": "tr|A0A8V0ZBD0-1|A0A8V0ZBD0_CHICK Isoform 1 of Calpain 10 OS=Gallus gallus OX=9031 GN=CAPN10 PE=3 SV=1 CANONICAL=A0A8V0ZBD0-1" }, "locus": { "chromosome": "9", "start_pos": 15405945, "end_pos": 15395343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043396.1", "url": "https://www.ensembl.org/id/ENSGALT00010043396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025795.1", "url": "https://www.ensembl.org/id/ENSGALP00010025795.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", 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"pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBD0" }, { "id": "PS50203", "database": "PROSITE", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZBG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PAVREEQEMRMRCFLHASAEELRNQQSNLLHSLCTDSYLDVEKTTQWFQKLIGNAWKCTHLSAVCSMNVTQSKRSCRLQVTDVYKKIFLVEMLFGVQQDDTDIFLSSQETEVGTTPSTTWPQSCAVAEAKFFLLVAARAEERNFYIRYMQVCAYILVGLNFSDYELKTVLMHLLTAIPLESWHGSYFLERIDDLLRYLRCCVEEKHLGHFFIGNEDVPAEIILPQDFRESEPLNLFQHLEDLEELQDRLMSLLIYGK", "length": 257, "header": "tr|A0A8V0ZBG7-1|A0A8V0ZBG7_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZBG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG7/entry#A0A8V0ZBG7-1", "sequence": { "sequence": "PAVREEQEMRMRCFLHASAEELRNQQSNLLHSLCTDSYLDVEKTTQWFQKLIGNAWKCTHLSAVCSMNVTQSKRSCRLQVTDVYKKIFLVEMLFGVQQDDTDIFLSSQETEVGTTPSTTWPQSCAVAEAKFFLLVAARAEERNFYIRYMQVCAYILVGLNFSDYELKTVLMHLLTAIPLESWHGSYFLERIDDLLRYLRCCVEEKHLGHFFIGNEDVPAEIILPQDFRESEPLNLFQHLEDLEELQDRLMSLLIYGK", "length": 257, "header": "tr|A0A8V0ZBG7-1|A0A8V0ZBG7_CHICK Isoform 1 of Mab-21-like HhH/H2TH-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZBG7-1" }, "locus": { "chromosome": "5", "start_pos": 54526865, "end_pos": 54525294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047819.1", "url": "https://www.ensembl.org/id/ENSGALT00010047819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028268.1", "url": "https://www.ensembl.org/id/ENSGALP00010028268.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG7" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 215, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZAS7-1", "uniprot_ac": "A0A8V0ZAS7", "uniprot_id": "A0A8V0ZAS7_CHICK", "mass": { "chemical_mass": 19997.0, "monoisotopic_mass": 19997.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Jupiter microtubule associated homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZAS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZAS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZAS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR033335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34930", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34930", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34930:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34930:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYFQGKISDSGLVLKPPGGGSSNLFGSAEEVSSSSKPHRMASNIFGASEEPQNLPKRTNPPGGKESGIFEDSGTAQPRPRMNPPGGKTSDIFGSPVSTSVVRAHPNKPKDHIVLKEDETPKKPEAAENKKPQLEDGGEKKDVGKEERCKEPEPKIDNHEPRLGPRPRSHNKVLNPPGGKSSIAFY", "length": 186, "header": "tr|A0A8V0ZAS7-1|A0A8V0ZAS7_CHICK Isoform 1 of Jupiter microtubule associated homolog 2 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZAS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7/entry#A0A8V0Z3F8-1", "sequence": { "sequence": "MDSCSHQPRGGAGATCSPGGQEGAPRGSRSRTMFQGPEAEPAKPSSRVLKPPGGGSSNLFGSAEEVSSSSKPHRMASNIFGASEEPQNLPKRTNPPGGKESGIFEDSGTAQPRPRMNPPGGKTSDIFGSPVSTSVVRAHPNKPKDHIVLKEDETPKKPEAAENKKPQLEDGGEKKDVGKEERCKEPEPKIDNHEPRLGPRPRSHNKVLNPPGGKSSIAFY", "length": 220, "header": "tr|A0A8V0Z3F8-1|A0A8V0Z3F8_CHICK Computationally mapped isoform of Jupiter microtubule associated homolog 2 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZAS7-1" }, "locus": { "chromosome": "14", "start_pos": 13689805, "end_pos": 13682433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046627.1", "url": "https://www.ensembl.org/id/ENSGALT00010046627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027770.1", "url": "https://www.ensembl.org/id/ENSGALP00010027770.1" } ] } }, { "isoform_ac": "A0A8V0ZAS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7/entry#A0A8V0ZAS7-1", "sequence": { "sequence": "MAYFQGKISDSGLVLKPPGGGSSNLFGSAEEVSSSSKPHRMASNIFGASEEPQNLPKRTNPPGGKESGIFEDSGTAQPRPRMNPPGGKTSDIFGSPVSTSVVRAHPNKPKDHIVLKEDETPKKPEAAENKKPQLEDGGEKKDVGKEERCKEPEPKIDNHEPRLGPRPRSHNKVLNPPGGKSSIAFY", "length": 186, "header": "tr|A0A8V0ZAS7-1|A0A8V0ZAS7_CHICK Isoform 1 of Jupiter microtubule associated homolog 2 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZAS7-1" }, "locus": { "chromosome": "14", "start_pos": 13686446, "end_pos": 13682433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046619.1", "url": "https://www.ensembl.org/id/ENSGALT00010046619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027762.1", "url": "https://www.ensembl.org/id/ENSGALP00010027762.1" } ] } }, { "isoform_ac": "A0A8V0ZAT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7/entry#A0A8V0ZAT2-1", "sequence": { "sequence": "MFQGPEAEPAKPSSRVLKPPGGGSSNLFGSAEEVSSSSKPHRMASNIFGASEEPQNLPKRTNPPGGKESGIFEDSGTAQPRPRMNPPGGKTSDIFGSPVSTSVVRAHPNKPKVLLQKIRNHSWKMVARKKMWAKRSDARSQNPR", "length": 144, "header": "tr|A0A8V0ZAT2-1|A0A8V0ZAT2_CHICK Computationally mapped isoform of Jupiter microtubule associated homolog 2 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZAS7-1" }, "locus": { "chromosome": "14", "start_pos": 13689709, "end_pos": 13682525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046625.1", "url": "https://www.ensembl.org/id/ENSGALT00010046625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027768.1", "url": "https://www.ensembl.org/id/ENSGALP00010027768.1" } ] } }, { "isoform_ac": "A0A8V0ZGQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7/entry#A0A8V0ZGQ3-1", "sequence": { "sequence": "MVLKPPGGGSSNLFGSAEEVSSSSKPHRMASNIFGASEEPQNLPKRTNPPGGKESGIFEDSGTAQPRPRMNPPGGKTSDIFGSPVSTSVVRAHPNKPKDHIVLKEDETPKKPEAAENKKPQLEDGGEKKDVGKEERCKEPEPKIDNHEPRLGPRPRSHNKVLNPPGGKSSIAFY", "length": 174, "header": "tr|A0A8V0ZGQ3-1|A0A8V0ZGQ3_CHICK Computationally mapped isoform of Jupiter microtubule associated homolog 2 OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZAS7-1" }, "locus": { "chromosome": "14", "start_pos": 13689420, "end_pos": 13682433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046622.1", "url": "https://www.ensembl.org/id/ENSGALT00010046622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027765.1", "url": "https://www.ensembl.org/id/ENSGALP00010027765.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of calcium-mediated signaling", "id": "GO:0050848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050848", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "pmid": "" }, { "name": "endocytosis involved in viral entry into host cell", "id": "GO:0075509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZA67-1", "uniprot_ac": "A0A8V0ZA67", "uniprot_id": "A0A8V0ZA67_CHICK", "mass": { "chemical_mass": 54301.0, "monoisotopic_mass": 54301.0 }, "refseq": {}, "gene_names": [ { "name": "ERMAP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67" } ] } ], "protein_names": [ { "name": "Tripartite motif containing 62", "type": "synonym", "evidence": [ { "id": "A0A8V0ZA67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZA67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERMAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZA67", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZA67", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13744", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13744", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16608", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16608", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TEHWNRQ", "url": "https://omabrowser.org/oma/group/TEHWNRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4D1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA67", "url": "https://www.orthodb.org/?gene=A0A8V0ZA67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSFGCEHYFCRRCITEHWVRQEPQGARDCPECRRTFTEPTLAPSLKLANIVERYSAFPLDAILGAQRSPFPCKDHEKVKLFCLTDRTVVCFFCDEPAVHEQHQVTNVDDAFEELQRELKEQLQGLQESERGHTEALHLLKRQLADTKSSAKSLRATIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKIQRYSQQLRKVQEGSQILQERLAEADKHAFLAGVASLSERLKGKIHETNLTYEDFPTSKYMGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPRRFDVEVSVLGTQAFGGGVHYWEVVVSEKTQWMIGLAHEAVTRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVKSKLEKVGVFLDYDKGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475, "header": "tr|A0A8V0ZA67-1|A0A8V0ZA67_CHICK Isoform 1 of Tripartite motif containing 62 OS=Gallus gallus OX=9031 GN=ERMAP PE=3 SV=1 CANONICAL=A0A8V0ZA67-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67/entry#A0A8V0Z4D1-1", "sequence": { "sequence": "MGVGYPADDVEFGHSTEFGDRGLGTAMADLGMTLSLGIMLNLGIVFWFRINAEWGTRVWFGGKAEIGGNAEFEDSAELGLNAEFGVCAELGCRRPCISSAVPAPSAPPPRPCASSRPSRPPAAPAMACSLKDELLCSICLSIYQDPVSFGCEHYFCRRCITEHWVRQEPQGARDCPECRRTFTEPTLAPSLKLANIVERYSAFPLDAILGAQRSPFPCKDHEKVKLFCLTDRTVVCFFCDEPAVHEQHQVTNVDDAFEELQRELKEQLQGLQESERGHTEALHLLKRQLADTKSSAKSLRATIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKIQRYSQQLRKVQEGSQILQERLAEADKHAFLAGVASLSERLKGKIHETNLTYEDFPTSKYMGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPRRFDVEVSVLGTQAFGGGVHYWEVVVSEKTQWMIGLAHEAVTRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVKSKLEKVGVFLDYDKGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 600, "header": "tr|A0A8V0Z4D1-1|A0A8V0Z4D1_CHICK Computationally mapped isoform of Tripartite motif containing 62 OS=Gallus gallus OX=9031 GN=ERMAP PE=3 SV=1 CANONICAL=A0A8V0ZA67-1" }, "locus": { "chromosome": "21", "start_pos": 6511497, "end_pos": 6507578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042874.1", "url": "https://www.ensembl.org/id/ENSGALT00010042874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025364.1", "url": "https://www.ensembl.org/id/ENSGALP00010025364.1" } ] } }, { "isoform_ac": "A0A8V0ZA67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA67/entry#A0A8V0ZA67-1", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSFGCEHYFCRRCITEHWVRQEPQGARDCPECRRTFTEPTLAPSLKLANIVERYSAFPLDAILGAQRSPFPCKDHEKVKLFCLTDRTVVCFFCDEPAVHEQHQVTNVDDAFEELQRELKEQLQGLQESERGHTEALHLLKRQLADTKSSAKSLRATIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKIQRYSQQLRKVQEGSQILQERLAEADKHAFLAGVASLSERLKGKIHETNLTYEDFPTSKYMGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPRRFDVEVSVLGTQAFGGGVHYWEVVVSEKTQWMIGLAHEAVTRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVKSKLEKVGVFLDYDKGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475, "header": "tr|A0A8V0ZA67-1|A0A8V0ZA67_CHICK Isoform 1 of Tripartite motif containing 62 OS=Gallus gallus OX=9031 GN=ERMAP PE=3 SV=1 CANONICAL=A0A8V0ZA67-1" }, "locus": { "chromosome": "21", "start_pos": 6511497, "end_pos": 6509105, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042872.1", "url": "https://www.ensembl.org/id/ENSGALT00010042872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025362.1", "url": "https://www.ensembl.org/id/ENSGALP00010025362.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BK51-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "TRIM62", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGMASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZA67", "url": "https://omabrowser.org/oma/group/A0A8V0ZA67/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SV81-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "TRIM62", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZA67", "url": "https://omabrowser.org/oma/group/A0A8V0ZA67/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R947-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "Trim62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSAREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKTHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZA67", "url": "https://omabrowser.org/oma/group/A0A8V0ZA67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80V85-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "Trim62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLKLANIVERYSAFPLDAILNARRAARPCQAHDKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFEELQRELKEQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTMDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZA67", "url": "https://omabrowser.org/oma/group/A0A8V0ZA67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVG3-1", "protein_name": "E3 ubiquitin-protein ligase TRIM62", "gene_name": "TRIM62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557046" } ] }, { "annotation": "Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. 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"id": "A0A8V0ZCK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD58", "url": "https://www.orthodb.org/?gene=A0A8V0ZD58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD62", "url": "https://www.orthodb.org/?gene=A0A8V0ZD62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ63", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ77", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10192:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10192:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-947581", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-947581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040557046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "31331", "url": "https://www.rhea-db.org/rhea/31331", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35047", "url": "https://www.rhea-db.org/rhea/35047", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AR23", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AR23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AR23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPSYTSSAVIMAKGEQPIPGLISYCHHAAGSAEEPIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDKKPDVFKEEGTQSFQNTAETGLPDCPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 796, "header": "tr|A0A8V0ZD58-1|A0A8V0ZD58_CHICK Isoform 1 of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A3Q3AR23-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPSYTSSAVIMAKGEQPIPGLISYCHHAAGSAEEPIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 741, "header": "tr|A0A3Q3AR23-1|A0A8V0ZD58_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048542.1", "url": "https://www.ensembl.org/id/ENSGALT00010048542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028633.1", "url": "https://www.ensembl.org/id/ENSGALP00010028633.1" } ] } }, { "isoform_ac": "A0A8V0Z5V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0Z5V5-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKARLPSCSSTYSVSELHYRLEGLKDELRRNRGYNSRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 790, "header": "tr|A0A8V0Z5V5-1|A0A8V0ZD58_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048546.1", "url": "https://www.ensembl.org/id/ENSGALT00010048546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028637.1", "url": "https://www.ensembl.org/id/ENSGALP00010028637.1" } ] } }, { "isoform_ac": "A0A8V0ZCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0ZCK6-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPSYTSSAVIMAKGEQPIPGLISYCHHAAGSAEEPIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 791, "header": "tr|A0A8V0ZCK6-1|A0A8V0ZCK6_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048550.1", "url": "https://www.ensembl.org/id/ENSGALT00010048550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028641.1", "url": "https://www.ensembl.org/id/ENSGALP00010028641.1" } ] } }, { "isoform_ac": "A0A8V0ZD58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0ZD58-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPSYTSSAVIMAKGEQPIPGLISYCHHAAGSAEEPIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDKKPDVFKEEGTQSFQNTAETGLPDCPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 796, "header": "tr|A0A8V0ZD58-1|A0A8V0ZD58_CHICK Isoform 1 of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048554.1", "url": "https://www.ensembl.org/id/ENSGALT00010048554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028645.1", "url": "https://www.ensembl.org/id/ENSGALP00010028645.1" } ] } }, { "isoform_ac": "A0A8V0ZD62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0ZD62-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPLCGLQRGATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 749, "header": "tr|A0A8V0ZD62-1|A0A8V0ZD58_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048559.1", "url": "https://www.ensembl.org/id/ENSGALT00010048559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028650.1", "url": "https://www.ensembl.org/id/ENSGALP00010028650.1" } ] } }, { "isoform_ac": "A0A8V0ZJ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0ZJ63-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKARLPSCSSTYSVSEVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 769, "header": "tr|A0A8V0ZJ63-1|A0A8V0ZD58_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048547.1", "url": "https://www.ensembl.org/id/ENSGALT00010048547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028638.1", "url": "https://www.ensembl.org/id/ENSGALP00010028638.1" } ] } }, { "isoform_ac": "A0A8V0ZJ77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58/entry#A0A8V0ZJ77-1", "sequence": { "sequence": "MASEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPSYTSSAVIMAKGEQPIPGLISYCHHAAGSAEEPIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL", "length": 772, "header": "tr|A0A8V0ZJ77-1|A0A8V0ZD58_CHICK Computationally mapped isoform of Gephyrin OS=Gallus gallus OX=9031 GN=GPHN PE=1 SV=1 CANONICAL=A0A8V0ZD58-1" }, "locus": { "chromosome": "5", "start_pos": 28835702, "end_pos": 28570596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048562.1", "url": "https://www.ensembl.org/id/ENSGALT00010048562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028653.1", "url": "https://www.ensembl.org/id/ENSGALP00010028653.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-947581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-947581", "resource": "Reactome", "description": "Molybdenum cofactor biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "molybdopterin adenylyltransferase activity", "id": "GO:0061598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061598", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "molybdopterin molybdotransferase activity", "id": "GO:0061599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "nitrate reductase activity", "id": "GO:0008940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": 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"UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "Mo-molybdopterin cofactor biosynthetic process", "id": "GO:0006777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "glycine receptor clustering", "id": "GO:0072579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD58" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid receptor clustering", "id": "GO:0097112", "url": 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"name": "", "equation": "molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9PW38-1", "A0A8V0ZD58-1" ], "evidence": [ { "id": "31331", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31331" } ] }, { "id": "35047", "name": "", "equation": "adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9PW38-1", "A0A8V0ZD58-1" ], "evidence": [ { "id": "35047", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35047" } ] }, { "id": "R-GGA-947531", "name": "Molybdenum ion transfer onto molybdopterin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-947496", "R-ALL-947561" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZD58-1" ], "evidence": [ { "id": "R-GGA-947531", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-947531" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-947496", "participant_name": "MPT [cytosol]", "crossref": [ { "id": "58698", "database": "ChEBI", "url": "" }, { "id": "ZINC000100069871", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-947561", "participant_name": "MoO4(2-) [cytosol]", "crossref": [ { "id": "36264", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZD58", "gene_name": "GPHN", "activity": [ { "ec_number": "2.10.1.1", "activity": "adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+).", "evidence": [ { "id": "A0A8V0ZD58", 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421395", "url": "https://www.ncbi.nlm.nih.gov/gene/421395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KRACRMP", "url": "https://omabrowser.org/oma/group/KRACRMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PAD1", "url": "https://www.orthodb.org/?gene=A0A1D5PAD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Q1", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCI7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCL3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZJY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C0L3", "url": "https://www.orthodb.org/?gene=E1C0L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937850", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PAD1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0L3", "url": "https://www.uniprot.org/uniprotkb/E1C0L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0L3-1", "url": "https://www.uniprot.org/uniprotkb/E1C0L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTVFYINPCLHKPEWVSKDLSLYNCRVEFFGIAIEFLKGTVKLGGSVLNI", "length": 706, "header": "tr|A0A8V0ZDZ1-1|A0A8V0ZDZ1_CHICK Isoform 1 of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A1D5PAD1-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTKNP", "length": 661, "header": "tr|A0A1D5PAD1-1|A0A8V0ZDZ1_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23742176, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048926.1", "url": "https://www.ensembl.org/id/ENSGALT00010048926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028916.1", "url": "https://www.ensembl.org/id/ENSGALP00010028916.1" } ] } }, { "isoform_ac": "A0A8V0Z6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0Z6Q1-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTFLITEKLVDMYTFFLS", "length": 674, "header": "tr|A0A8V0Z6Q1-1|A0A8V0ZDZ1_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23731158, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048920.1", "url": "https://www.ensembl.org/id/ENSGALT00010048920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028913.1", "url": "https://www.ensembl.org/id/ENSGALP00010028913.1" } ] } }, { "isoform_ac": "A0A8V0ZCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZCI7-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTVTLAALSGCQVWLWMYAQLCG", "length": 679, "header": "tr|A0A8V0ZCI7-1|A0A8V0ZCI7_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23743586, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048933.1", "url": "https://www.ensembl.org/id/ENSGALT00010048933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028920.1", "url": "https://www.ensembl.org/id/ENSGALP00010028920.1" } ] } }, { "isoform_ac": "A0A8V0ZCL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZCL3-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSERGEVLEQVAQ", "length": 660, "header": "tr|A0A8V0ZCL3-1|A0A8V0ZCL3_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23827173, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048967.1", "url": "https://www.ensembl.org/id/ENSGALT00010048967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028945.1", "url": "https://www.ensembl.org/id/ENSGALP00010028945.1" } ] } }, { "isoform_ac": "A0A8V0ZCM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZCM3-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTISCFPLGLQRKLSVKGTDDWDVLD", "length": 682, "header": "tr|A0A8V0ZCM3-1|A0A8V0ZCM3_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23900550, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048982.1", "url": "https://www.ensembl.org/id/ENSGALT00010048982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028955.1", "url": "https://www.ensembl.org/id/ENSGALP00010028955.1" } ] } }, { "isoform_ac": "A0A8V0ZDG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZDG5-1", "sequence": { "sequence": "MLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMVSIKENLGIDQSVETICPLNTN", "length": 563, "header": "tr|A0A8V0ZDG5-1|A0A8V0ZDG5_CHICK Computationally mapped isoform of Metastasis associated 1 family member 3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23719812, "end_pos": 23633850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048918.1", "url": "https://www.ensembl.org/id/ENSGALT00010048918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028912.1", "url": "https://www.ensembl.org/id/ENSGALP00010028912.1" } ] } }, { "isoform_ac": "A0A8V0ZDX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZDX2-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMFVFQEQGNT", "length": 606, "header": "tr|A0A8V0ZDX2-1|A0A8V0ZDX2_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23720177, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048914.1", "url": "https://www.ensembl.org/id/ENSGALT00010048914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028911.1", "url": "https://www.ensembl.org/id/ENSGALP00010028911.1" } ] } }, { "isoform_ac": "A0A8V0ZDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZDZ1-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTVFYINPCLHKPEWVSKDLSLYNCRVEFFGIAIEFLKGTVKLGGSVLNI", "length": 706, "header": "tr|A0A8V0ZDZ1-1|A0A8V0ZDZ1_CHICK Isoform 1 of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23746428, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048948.1", "url": "https://www.ensembl.org/id/ENSGALT00010048948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028931.1", "url": "https://www.ensembl.org/id/ENSGALP00010028931.1" } ] } }, { "isoform_ac": "A0A8V0ZJY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#A0A8V0ZJY4-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETSAEAVRNLLTRTVFL", "length": 663, "header": "tr|A0A8V0ZJY4-1|A0A8V0ZJY4_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=1 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23737505, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048922.1", "url": "https://www.ensembl.org/id/ENSGALT00010048922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028914.1", "url": "https://www.ensembl.org/id/ENSGALP00010028914.1" } ] } }, { "isoform_ac": "E1C0L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1/entry#E1C0L3-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKIWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSNNGKPATVNGAMGASYQAQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKLSSSQPAEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHYEIAGNPLKIKSTRKPLSCIIGYLEIHPAMKPNVIRSTPSLQSPSTKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHSTRTIMHAAPRVHITNGKALQASASTIKTSAIPVIKRQRQNWLDASDDGFFIATEETRKIRKKFSSLQLKRASRTPCSPILAKTKSLMNNRQARIEPRTITH", "length": 693, "header": "tr|E1C0L3-1|A0A8V0ZDZ1_CHICK Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Gallus gallus OX=9031 GN=MTA3 PE=3 SV=3 CANONICAL=A0A8V0ZDZ1-1" }, "locus": { "chromosome": "3", "start_pos": 23742300, "end_pos": 23630647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048932.1", "url": "https://www.ensembl.org/id/ENSGALT00010048932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028919.1", "url": "https://www.ensembl.org/id/ENSGALP00010028919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTK6-1", "protein_name": "Metastasis-associated protein MTA3", "gene_name": "Mta3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEESETTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDVLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISSSNGKAGTVNGAVGTPFQPQSALLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQTDEEKAPSPAAEDPRVRSHLSRQALQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTTPNHTSLSILGKRNYSHHNGLDASKIRMANSLIFGRGGHELRSLQLETVKEIAFVSPVDQRAESPSPRASSTSE", "length": 637 }, "evidence": [ { "id": "A0A8V0ZDZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q924K8-1", "protein_name": "Metastasis-associated protein MTA3", "gene_name": "Mta3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEESETPVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEACLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISSSNGKAGTVNGAVGTQFQPQSALLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSDEEKSPSPTAEDPRARSHMSRQALQGMPVRNTGSPKSAVKTRQAFFLRTTYFTKIARQVCKSTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSRSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPATKRMLAAPNHTSLSILGKRNYSHHNGLDGPERWLSR", "length": 591 }, "evidence": [ { "id": "A0A8V0ZDZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTC8-1", "protein_name": "Metastasis-associated protein MTA3", "gene_name": "MTA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAVNGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPTQSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSKSTRKPLACIIGYLEIHPAKKPNVIRSTPSLQTPTTKRMLTTPNHTSLSILGKRNYSHHNGLDELTCCVSD", "length": 594 }, "evidence": [ { "id": "A0A8V0ZDZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" }, { "id": "PS51038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAH", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 147, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 259, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ1" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 266, "end_pos": 318, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 578, "end_pos": 580 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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"MLSALPPCILALEELPYATGNTHCNLNSAPVEGASSAPEMQGEMLQKWAGQMQRPVKQSLSACMCRESHWKCLLLSILMYGCLGAVAWCQLARVTKLSFDSSFKGKSMIYHDSPCSDGYVYIPLAFLSMLYVVYLVECWHCHVKRELQYKADVDSVYECINRMQQATPCIWWKAISYHFVRRTRQVTRYRNGDAYTTTQVYHERVNTHVAEAEFDYSHCGYKDISKELLGLESYTATKLRFTKCFSFANIESENSYLTQRAHFFTEIEGLDDYMEVREGMQLKNVDFKELMMAYGDPDHLPWYVSHYAFWVAAILMISWPLRVLIEYRTAYVHYHVEKLLGLEYTAPTTTEEPLYRYRMPRDATQDSTELEWHICTNRQLIPSYSEAMLMDLADSPAYNSYTVCRYSEVAHGCERCNHASSTSSIFSRHAFHSCSGNSRLSLNTSRFSLCRVHGSHRTGLWRSRSSSIADRGCHDEQCCSYSSQLAVNENPPTYHDARFFPVLIVHRPEGHDGQPFYVRRSSCLETSL", "length": 528, "header": "tr|A0A8V0ZBU2-1|A0A8V0ZBU2_CHICK Isoform 1 of Transmembrane protein 151B OS=Gallus gallus OX=9031 GN=LOC771422 PE=3 SV=1 CANONICAL=A0A8V0ZBU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU2/entry#A0A8V0ZBU2-1", "sequence": { "sequence": 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"url": "https://www.ensembl.org/id/ENSGALP00010028684.1" } ] } }, { "isoform_ac": "A0A8V0ZCR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU2/entry#A0A8V0ZCR0-1", "sequence": { "sequence": "MSSEGEAEAAAESGPGSSPAPGPAAAEREEQRPVKQSLSACMCRESHWKCLLLSILMYGCLGAVAWCQLARVTKLSFDSSFKGKSMIYHDSPCSDGYVYIPLAFLSMLYVVYLVECWHCHVKRELQYKADVDSVYECINRMQQATPCIWWKAISYHFVRRTRQVTRYRNGDAYTTTQVYHERVNTHVAEAEFDYSHCGYKDISKELLGLESYTATKLRFTKCFSFANIESENSYLTQRAHFFTEIEGLDDYMEVREGMQLKNVDFKELMMAYGDPDHLPWYVSHYAFWVAAILMISWPLRVLIEYRTAYVHYHVEKLLGLEYTAPTTTEEPLYRYRMPRDATQDSTELEWHICTNRQLIPSYSEAMLMDLADSPAYNSYTVCRYSEVAHGCERCNHASSTSSIFSRHAFHSCSGNSRLSLNTSRFSLCRVHGSHRTGLWRSRSSSIADRGCHDEQCCSYSSQLAVNENPPTYHDARFFPVLIVHRPEGHDGQPFYVRRSSCLETSL", "length": 506, "header": "tr|A0A8V0ZCR0-1|A0A8V0ZCR0_CHICK Computationally mapped isoform of Transmembrane protein 151B OS=Gallus gallus OX=9031 GN=LOC771422 PE=3 SV=1 CANONICAL=A0A8V0ZBU2-1" }, "locus": { "chromosome": "5", "start_pos": 24440866, "end_pos": 24423466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048596.1", "url": "https://www.ensembl.org/id/ENSGALT00010048596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028686.1", "url": "https://www.ensembl.org/id/ENSGALP00010028686.1" } ] } }, { "isoform_ac": "F1NLS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU2/entry#F1NLS4-1", "sequence": { "sequence": "MCRESHWKCLLLSILMYGCLGAVAWCQLARVTKLSFDSSFKGKSMIYHDSPCSDGYVYIPLAFLSMLYVVYLVECWHCHVKRELQYKADVDSVYECINRMQQATPCIWWKAISYHFVRRTRQVTRYRNGDAYTTTQVYHERVNTHVAEAEFDYSHCGYKDISKELLGLESYTATKLRFTKCFSFANIESENSYLTQRAHFFTEIEGLDDYMEVREGMQLKNVDFKELMMAYGDPDHLPWYVSHYAFWVAAILMISWPLRVLIEYRTAYVHYHVEKLLGLEYTAPTTTEEPLYRYRMPRDATQDSTELEWHICTNRQLIPSYSEAMLMDLADSPAYNSYTVCRYSEVAHGCERCNHASSTSSIFSRHAFHSCSGNSRLSLNTSRFSLCRVHGSHRTGLWRSRSSSIADRGCHDEQCCSYSSQLAVNENPPTYHDARFFPVLIVHRPEGHDGQPFYVRRSSCLETSL", "length": 465, "header": "tr|F1NLS4-1|A0A8V0ZBU2_CHICK Computationally mapped isoform of Transmembrane protein 151B OS=Gallus gallus OX=9031 GN=LOC771422 PE=3 SV=3 CANONICAL=A0A8V0ZBU2-1" }, "locus": { "chromosome": "5", "start_pos": 24440866, "end_pos": 24439472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048588.1", "url": "https://www.ensembl.org/id/ENSGALT00010048588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028679.1", "url": "https://www.ensembl.org/id/ENSGALP00010028679.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771422", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 443, "end_pos": 445 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBH9-1", "uniprot_ac": "A0A8V0ZBH9", "uniprot_id": "A0A8V0ZBH9_CHICK", "mass": { "chemical_mass": 106532.0, "monoisotopic_mass": 106532.0 }, "refseq": { "ac": "XP_015141558", "name": "solute carrier family 4 member 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141558" }, "gene_names": [ { "name": "SLC4A11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ] }, { "name": "SLC4A11", "type": "synonym", "evidence": [ { "id": "XP_015141558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141558" } ] } ], "protein_names": [ { "name": "Solute carrier family 4 member 11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#names_and_taxonomy" } ] }, { "name": "Sodium borate cotransporter 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 4 member 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141558" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015141558.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141558" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC4A11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9", "locus": { "chromosome": "4", "start_pos": 88456856, "end_pos": 88584697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017983", "url": "https://www.ensembl.org/id/ENSGALG00010017983" } ] } } ], "crossref": [ { "id": "A0A8V0ZBH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "422943", "url": "https://www.ncbi.nlm.nih.gov/gene/422943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422943", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422943", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AIFHWIV", "url": "https://omabrowser.org/oma/group/AIFHWIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YXQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXR0", "url": "https://www.orthodb.org/?gene=A0A8V0YXR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXR7", "url": "https://www.orthodb.org/?gene=A0A8V0YXR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4J2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5K9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5L4", "url": "https://www.orthodb.org/?gene=A0A8V0Z5L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5M7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141558", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66816", "url": "https://www.rhea-db.org/rhea/66816", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YXQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQQYQLKEVKADAVCFVPGSPLFSVLMEPASFCYPQLTFLRSPYGQFGASAGSSQDLAPWPQRLVPQRWSGPVDESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNGIHDVSEPTGMNIQTCTSHLKFHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 948, "header": "tr|A0A8V0ZBH9-1|A0A8V0ZBH9_CHICK Isoform 1 of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0YXQ5-1", "sequence": { "sequence": "MRGKREAAMAARRVFHLQPCGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 855, "header": "tr|A0A8V0YXQ5-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88545137, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043465.1", "url": "https://www.ensembl.org/id/ENSGALT00010043465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025839.1", "url": "https://www.ensembl.org/id/ENSGALP00010025839.1" } ] } }, { "isoform_ac": "A0A8V0YXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0YXR0-1", "sequence": { "sequence": "MRGKREAAMAARRVFHLQPCESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 872, "header": "tr|A0A8V0YXR0-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88545137, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043470.1", "url": "https://www.ensembl.org/id/ENSGALT00010043470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025844.1", "url": "https://www.ensembl.org/id/ENSGALP00010025844.1" } ] } }, { "isoform_ac": "A0A8V0YXR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0YXR7-1", "sequence": { "sequence": "MELTPVRTSNMEGEGQSGALYPLHPGKVKDESKKAPDNGNALAIQAESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNGIHDVSEPTGMNIQTCTSHLKFHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 919, "header": "tr|A0A8V0YXR7-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88584605, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043480.1", "url": "https://www.ensembl.org/id/ENSGALT00010043480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025850.1", "url": "https://www.ensembl.org/id/ENSGALP00010025850.1" } ] } }, { "isoform_ac": "A0A8V0Z4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0Z4J2-1", "sequence": { "sequence": "MSQQYQLKEVKADAVCFVPGSPLFSVLMEPASFCYPQLTFLRSPYGQFGASAGSSQDLAPWPQRLVPQRWSGPVDESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 927, "header": "tr|A0A8V0Z4J2-1|A0A8V0Z4J2_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88540942, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043462.1", "url": "https://www.ensembl.org/id/ENSGALT00010043462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025838.1", "url": "https://www.ensembl.org/id/ENSGALP00010025838.1" } ] } }, { "isoform_ac": "A0A8V0Z5K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0Z5K9-1", "sequence": { "sequence": "MSQQYQLKEVKADAVCFVPGSPLFSVLMEPASFCYPQLTFLRSPYGQFGASAGSSQDLAPWPQRLVPQRWSGPVDESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPISAGMQ", "length": 911, "header": "tr|A0A8V0Z5K9-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88540942, "end_pos": 88460974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043448.1", "url": "https://www.ensembl.org/id/ENSGALT00010043448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025827.1", "url": "https://www.ensembl.org/id/ENSGALP00010025827.1" } ] } }, { "isoform_ac": "A0A8V0Z5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0Z5L4-1", "sequence": { "sequence": "MDTSLKRVARYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 844, "header": "tr|A0A8V0Z5L4-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88528569, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043455.1", "url": "https://www.ensembl.org/id/ENSGALT00010043455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025832.1", "url": "https://www.ensembl.org/id/ENSGALP00010025832.1" } ] } }, { "isoform_ac": "A0A8V0Z5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0Z5M7-1", "sequence": { "sequence": "MELTPVRTSNMEGEGQSGALYPLHPGKVKDESKKAPDNGNALAIQAGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 881, "header": "tr|A0A8V0Z5M7-1|A0A8V0ZBH9_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88584605, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043475.1", "url": "https://www.ensembl.org/id/ENSGALT00010043475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025847.1", "url": "https://www.ensembl.org/id/ENSGALP00010025847.1" } ] } }, { "isoform_ac": "A0A8V0ZBH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0ZBH9-1", "sequence": { "sequence": "MSQQYQLKEVKADAVCFVPGSPLFSVLMEPASFCYPQLTFLRSPYGQFGASAGSSQDLAPWPQRLVPQRWSGPVDESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNGIHDVSEPTGMNIQTCTSHLKFHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 948, "header": "tr|A0A8V0ZBH9-1|A0A8V0ZBH9_CHICK Isoform 1 of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88540942, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043459.1", "url": "https://www.ensembl.org/id/ENSGALT00010043459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025835.1", "url": "https://www.ensembl.org/id/ENSGALP00010025835.1" } ] } }, { "isoform_ac": "A0A8V0ZBJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9/entry#A0A8V0ZBJ0-1", "sequence": { "sequence": "MEMFPVRESPPAAMSRNGYFFEESGYLKCDTDDGCEAKEETGGEELFDAVNSSIVSGDSIRFFVNVNLEVPPNTAAENESAGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILDETATSLDDVLREMLKHFAEDPENTEPSCNFEKIMSTLFTDSGTPREGNVHLLSDTIQGVTATVTGVQYQQSWLCIICTIKSLQRRHVCISRLERPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQRHLLTVVNQRPSAMSDGHMPHGPKPLKLHEFLNVGKGIFDDIARRFPVYALDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDENTRGAIDVQKTIVGQCIGGLLYALFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFSAFYAWIGLWNSFFLVMYSLFNFSLLMKLFKRSTEEIIALFISITFVLDAFKGIIKVFKKYYYHGRTGDSYLEKARTDAIPSLGINTTFLMNSSVSRSMSLENQTGTHDVHYGRETAVLSLMLMLGTLWLGHTLYQFKKSPYLHARVREILSDCALPISVLTFSVVGSYIFKEIEMSKFNYNPSESLFVLAPVQSLSIGSVMSAMGLGFLLSMLFFIEQNIVASLTNAPENRLVKGTAYHWDLLLVALINTGLSIFGLPWIHAAFPHSPMHVRALAYVEERVENGHIYETIVSVKETRLTSLVANFLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLFERVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLILCGFGMSPLPYMKMIFPLIMIGMIPIRYNLLPRIIEAKYLDAMDAEH", "length": 859, "header": "tr|A0A8V0ZBJ0-1|A0A8V0ZBJ0_CHICK Computationally mapped isoform of Solute carrier family 4 member 11 OS=Gallus gallus OX=9031 GN=SLC4A11 PE=3 SV=1 CANONICAL=A0A8V0ZBH9-1" }, "locus": { "chromosome": "4", "start_pos": 88568614, "end_pos": 88458169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043471.1", "url": "https://www.ensembl.org/id/ENSGALT00010043471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025845.1", "url": "https://www.ensembl.org/id/ENSGALP00010025845.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422943", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422943", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QDU4-1", "protein_name": "Solute carrier family 4 member 11", "gene_name": "SLC4A11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATATRRAFHLQPCEASSVMSQSGYPEDPGYLKCDTDDASETREESLGDEAFDTVNSSIVSGESIRFFVNVNLEVQPTQSESELPGGYGLLHTSRKYLKLKNFEEEVRAHRDLDGFLARASIILNETATSLDDVLRAMLYRLAQDPHNTEPDCHLDLLMAMLFTDAGAPMEDKGVHLLSDTIQGVTATVTGVHYQQSWLCIICTSKALVKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTATEVGRTFATMFLDIAFRQKLLKTRTEEEFKEALVHQRQLLTMMSQSAGTRMTDHSMNSICLHKPPKPPQHTDFFPLGKGIREDIARRFPVYPLDFTDGIIGKNKAVGKFITTTLFLYFACLLPTIAFGSLNDENTHGAIDVQKTMAGQSIGGLLYALFSGQPLVVLLTTAPLALYIHVIRGICDDYDLDFNTFYAWTGLWNSFFLALYALFNLSLVMSLFKRSTEEIIALFISITFMLDAVKGMVKIFQKYYYGQNLENIYAYSSSSVNLLGLSTSLNSSLHSALNSSLLAGPPELTSGGSPAPEPPARDTAVLSLLIMLGTLWLSYTLYQFKKSPYLHPYMREILSDCALPISVLTFSLICSYGFREIKMGKFRYNPSESLFEMPEMHSLSLAAISSAMGLGFLLSLLFFIEQNLVAALANAPENRLVKGTAYHWDLLLIAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVNVRETRLTTLGASILVGFSLLLLPFPLQWIPKPVLYGLFLYIALTSIDGNQLCARMALLLKDQTSYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSTLPYMKMIFPLIMIVMVPIRYNLLPRIIEAKYLDAMDAEH", "length": 876 }, "evidence": [ { "id": "A0A8V0ZBH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBH9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2AJN7-1", "protein_name": "Solute carrier family 4 member 11", "gene_name": "Slc4a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQNEHCQDSGEYFSAGTQGYFKNNMEDNLEVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDLEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGVQYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP", "length": 862 }, "evidence": [ { "id": "A0A8V0ZBH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZVP9-1", "protein_name": "Solute carrier family 4 member 11", "gene_name": "Slc4a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQNEHCQDSGEYFSAATLGYFKNDTDDNPDVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDIEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFAQDPNHAEPDCDLDLLMAKLFTDAGGPMESKVHLLSDTIQGVTATVRGLQYEQSWLCIVCTMKSLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPRPPKCKDFFPFGKGIWVDIMRRFPVYPLDFTDGIIGKGKTVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFWKYYYGHHYHTKRTSSLASLLGISRSPNTSLHTALNTSFLASPIEMTTASSPISTHSNQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLISSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAISSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVNVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP", "length": 862 }, "evidence": [ { "id": "A0A8V0ZBH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55BP1-1", "protein_name": "Bicarbonate transporter-like transmembrane domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLVEKKNIQHSPINWKLDTRSKLDLEQSKDCLYFFEQESNEQQQQSLVDIVYFLYDNVINDFIKNKNKNQINNRDIFKTNIFNNDNKNSLKEYIKIEKYLILWCSLDNIKENAYCFYRLNNNNNNNENNNNNNKNNLEYLILIVGPTQIQQSKSSEEIAKSFSSAISYPSVQYQLHQARNKQEVIESFVTFLNNIENDNENQFERKLIPPIKNNNNYKEQNNESLKPLESVSNGLDHENYDNDDDDDDINDDTNINNKENSKLNFKYLINDIKYRYDFEIYKSDWKDGLKDWKSFQKTLSTTVFLFFAILLPSIAFGVLNYSNTEGLLGVSKTIIAQGIGGMIFALLSGQPMVILLSTAPLAIFIKITYSISIENGLDFYSLYSMIGLFNGFFLIIYSISGASRLMKYSSRFIEETFAIFITIAFLYDGIKPIVVLFIDNLYSCDNNCQLTNQTPVFTLLISLCTLWICFKLSNFNQTKYFNGVFRNLISDYALFLGVLISSAIRWTVFLPLEDEHFSHGLDDLLNTEIKMLPVWAYFLALALGFLLSLLYFVDQNISCSLATTPSHNLKKWSGVHLDLLIVAFINIVLSFLGLPWLHGALPHSSLHVRALATIESFTDTSTGETKEIFISVQETRASGFFSHLLIFICIFLVSNILIYIPIPVLYGVFFFLGVKATVGNQFWYRILLLITDNTFLPNSNMIRYCTKLEIHKFTTFQIICLLIFCFISFYPNPYLTIFFPLFLTILIPIKNYLLPIYFKKIIINILDN", "length": 768 }, "evidence": [ { "id": "A0A8V0ZBH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBH9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NBS3-3", "protein_name": "Solute carrier family 4 member 11", "gene_name": "SLC4A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAATRRVFHLQPCENSPTMSQNGYFEDSSYYKCDTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNFKEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLFTDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP", "length": 875 }, "evidence": [ { "id": "A0A8V0ZBH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "solute:inorganic anion antiporter activity", "id": "GO:0005452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH9" } ], "pmid": "" }, { "name": "water 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z611", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z611", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z611-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z611-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z614", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z614", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z614-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z614-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEPGVNEKRASHFLPWHYRKKKKRKKKKKATESLNSF", "length": 487, "header": "tr|A0A8V0ZBX3-1|A0A8V0ZBX3_CHICK Isoform 1 of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A1D5PG19-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEVR", "length": 422, "header": "tr|A0A1D5PG19-1|A0A8V0ZBX3_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=2 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50308821, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043653.1", "url": "https://www.ensembl.org/id/ENSGALT00010043653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025972.1", "url": "https://www.ensembl.org/id/ENSGALP00010025972.1" } ] } }, { "isoform_ac": "A0A8V0YY37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0YY37-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEVR", "length": 430, "header": "tr|A0A8V0YY37-1|A0A8V0ZBX3_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50308821, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043639.1", "url": "https://www.ensembl.org/id/ENSGALT00010043639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025960.1", "url": "https://www.ensembl.org/id/ENSGALP00010025960.1" } ] } }, { "isoform_ac": "A0A8V0Z4C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z4C4-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPEAAEGQSGKMVSDMEVSVKQRCVNEFLHEEKKERADTHQCLMNVYGDETVGAR", "length": 453, "header": "tr|A0A8V0Z4C4-1|A0A8V0Z4C4_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate CoA-transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50281030, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043629.1", "url": "https://www.ensembl.org/id/ENSGALT00010043629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025952.1", "url": "https://www.ensembl.org/id/ENSGALP00010025952.1" } ] } }, { "isoform_ac": "A0A8V0Z4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z4C9-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPVHTPRTSNVSSFCEACGFACTQM", "length": 423, "header": "tr|A0A8V0Z4C9-1|A0A8V0Z4C9_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate CoA-transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50289158, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043636.1", "url": "https://www.ensembl.org/id/ENSGALT00010043636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025957.1", "url": "https://www.ensembl.org/id/ENSGALP00010025957.1" } ] } }, { "isoform_ac": "A0A8V0Z4E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z4E8-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEVE", "length": 454, "header": "tr|A0A8V0Z4E8-1|A0A8V0Z4E8_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50309321, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043661.1", "url": "https://www.ensembl.org/id/ENSGALT00010043661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025977.1", "url": "https://www.ensembl.org/id/ENSGALP00010025977.1" } ] } }, { "isoform_ac": "A0A8V0Z4X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z4X5-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKLAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEVR", "length": 437, "header": "tr|A0A8V0Z4X5-1|A0A8V0Z4X5_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50308821, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043643.1", "url": "https://www.ensembl.org/id/ENSGALT00010043643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025964.1", "url": "https://www.ensembl.org/id/ENSGALP00010025964.1" } ] } }, { "isoform_ac": "A0A8V0Z611-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z611-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLR", "length": 433, "header": "tr|A0A8V0Z611-1|A0A8V0ZBX3_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50309316, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043667.1", "url": "https://www.ensembl.org/id/ENSGALT00010043667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025983.1", "url": "https://www.ensembl.org/id/ENSGALP00010025983.1" } ] } }, { "isoform_ac": "A0A8V0Z614-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0Z614-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPEPEESSAGAGFPDCIPLL", "length": 418, "header": "tr|A0A8V0Z614-1|A0A8V0ZBX3_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50410545, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043677.1", "url": "https://www.ensembl.org/id/ENSGALT00010043677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025988.1", "url": "https://www.ensembl.org/id/ENSGALP00010025988.1" } ] } }, { "isoform_ac": "A0A8V0ZBV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0ZBV6-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEVR", "length": 454, "header": "tr|A0A8V0ZBV6-1|A0A8V0ZBV6_CHICK Computationally mapped isoform of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50308821, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043646.1", "url": "https://www.ensembl.org/id/ENSGALT00010043646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025966.1", "url": "https://www.ensembl.org/id/ENSGALP00010025966.1" } ] } }, { "isoform_ac": "A0A8V0ZBX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3/entry#A0A8V0ZBX3-1", "sequence": { "sequence": "MLGTELVWRSCGRGLWRSLCRAAGGSPRALSAASSSACEGARGGGAPPAGASNVKPLDGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGTGDDTRAWGPPFVGTESVYFLSVNRNKKSIAINMKNSRGAKLIRELAAVSDVFVENYIPGKLAEIGLGYEDIAKIAPHIVYCSITGYGQTGPMVQRGGYDSIAAAISGLTHITGHEGGEPVRVGVAMTDLATGLYACGAIMAGLLQKYKTGKGMHIDCNLLSSQVACLTHVAANYLNCKIEAKRWGTAHGSIVPYQAFKTEDGYIVVGAGNDQQFVTVCQILNLPEVIKDSRYKTNKLRVQNRKELIDILSTRFSEKTTVEWLQLFEGSGVPYGPINNMQQVFSEPQVLHNELVMEMDHPIAGRIAVPGPGVRYSEFVVSHPKPPPLVGQHTVEILKGMLRYEDDAIEELLRTGVVAQHEPGVNEKRASHFLPWHYRKKKKRKKKKKATESLNSF", "length": 487, "header": "tr|A0A8V0ZBX3-1|A0A8V0ZBX3_CHICK Isoform 1 of Succinyl-CoA:glutarate-CoA transferase OS=Gallus gallus OX=9031 GN=SUGCT PE=1 SV=1 CANONICAL=A0A8V0ZBX3-1" }, "locus": { "chromosome": "2", "start_pos": 50333634, "end_pos": 49982359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043672.1", "url": "https://www.ensembl.org/id/ENSGALT00010043672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025986.1", "url": "https://www.ensembl.org/id/ENSGALP00010025986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420768", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q55CV9-1", "protein_name": "CaiB/baiF CoA-transferase family protein DDB_G0269880", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFLNKLIKNKYKQNFFSFKNYCTINNNKPLNGFKILDLSRVLAGPYATQIFGDLGAQVIKVENVGKGDDTRQYGPPFYVDEQGRKGSAYFSCANRNKKSIALDISTKEGQDIVYSLAKESDVFIENFKVGGLKKYSLDYETIKQINPSIIYCSITGFGQDGEYSKLPGYDFSVQAMGGLISITGDKENPYKCGVAIVDMMTGLYANIAIQAALHHREKSKDKKGQYIDVSLLDVQASFLANHGSSYLVTGETSERVGNSHPSISPYDSLKTKDGFMVVAIGNNTQFQSMCNVLGLPHLSTNPLFSTNPSRVLNRKQLLSILTNETLKFNTDDIVKLLGDSNVPCSPINSIDKVVNHKQIKHRNMIWNLPLNENNNNNLNNNNLNNNNSNNNLNNNNNNNKNIQNDKGEYIMNSINLIGNPIHFSETNIHTPSSIKSNIPPPFLGQHTDEILKNIGLNENQILNLKNNNIVQ", "length": 471 }, "evidence": [ { "id": "A0A8V0ZBX3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBX3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q68FU4-1", "protein_name": "Succinyl-CoA:glutarate CoA-transferase", "gene_name": "Sugct", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRMLARAVAFRRSGRGQAGGRGLWTGRPQSDCDSMKPLEGVRILDLTRVLAGPFATMNLGDLGAEVIKVERPGAGDDTRSWGPPFVNTESTYFLSVNRNKKSIAVNIKDPRGVRIVKELAAICDVFVENYVPGKLSEMGLGYADIDKIAPHIVYCSITGYGQTGPMSHRAGYDAIASAMSGLMHITGPEDGDPVRPGVAMTDLATGLFAYGAIMAGLIQRYRTGKGLFIDCNLLSSQVACLTQVAANYLIGQKEAKRWGTAHGSIVPYQAFKTKDGYLVIGAGNNQQFAVLCKILNLPELIDDSKYRTNHLRVQNRKELVKILSARFAEEVTAKWLCLFEGSGIPYGPINSLKDVFSEAQVLHNGLVMEMNHPTVGKISVPGPAVRYSKFKMSEAKPPPLLGQHTRHILKEVLRYDEGVIGELLCSGVIEQHETE", "length": 436 }, "evidence": [ { "id": "A0A8V0ZBX3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TNE1-1", "protein_name": "Succinyl-CoA:glutarate CoA-transferase", "gene_name": "Sugct", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWMLARAVAFRRPGRGLAGGRGLWTGRPQSDCDSMKPLEGVRILDLTRVLAGPFATMNLGDLGAEVIKVERPGAGDDTRSWGPPFVNTESTYFLSVNRNKKSIAVNIKDPRGVRIVKELAAICDVFVENYVPGKLSEMGLGYEDIDKIAPHIIYCSITGYGQTGPMSHRAGYDAIASAMSGLMHITGPEDGDPVRPGVAMTDLATGLFAYGAIMAGLLQRYRTGKGLFIDCNLLSSQVACLTQVAANYLIGQKEAKRWGTAHGSIVPYQAFKTKDGYLVIGAGNNQQFAVVCKILNLPELIDDCKYRTNHLRVQNRKELVKILSARFAEEVTAKWLCLFEGSGIPYGPINSLKDVFSEAQVLHNGLVMEMNHPTVGKISVPGPAVRYSKFKMSEAKPPPLLGQHTRHILKEVLRYDEGAIEKLLCSGVIEQHETK", "length": 436 }, "evidence": [ { "id": "A0A8V0ZBX3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDL4-1", "protein_name": "Succinate--hydroxymethylglutarate CoA-transferase", "gene_name": "Dmel\\CG10877", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSQNLRLVRGLLNYGVCRPSLRNFAAVGDKNNAADNANASDVDERHPLHGIRILDLSRIIAGPYCTMVLADLGAEVIKVERPHFGDEARKWGPPFLKNSNDAAYFLAPNRNKRSICIDIKRGTQLLHRLAEISDVLVENYVPGTLERYGLGYEQLRKVNPKLIYCSMTGYGSVGPYAKRPGYDVIASSVGGLMHITGERDGPPSKVGVAVTDMSTGLYAHGAILAALYQRTRTQRGQKIEVDLLSTCCSLLLNVGSNYLNSGVEAGRMGTAHSSIVPYQSFKTKDGYLTLGTGSDVQFVDLCRRLKVEHLAQNPKFKTNKDRVTNRVELLGILEQMLSEDTSRNWMKLFEGASFPVGPVNSIPEVFEDEHIKAIGLVKSLRHPKDETVKVVGPPVTFSEARNDARTAPPILGQHTDEVLGELLGYGPDELAKLKKDNIIQ", "length": 441 }, "evidence": [ { "id": "A0A8V0ZBX3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBX3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3" } ], "pmid": "" }, { "name": "succinate-hydroxymethylglutarate CoA-transferase activity", "id": "GO:0047369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12284", "name": "", "equation": "3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "12284", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12284" } ] }, { "id": "38283", "name": "", "equation": "itaconate + succinyl-CoA = itaconyl-CoA + succinate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "38283", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38283" } ] }, { "id": "67900", "name": "", "equation": "glutarate + succinyl-CoA = glutaryl-CoA + succinate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "67900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67900" } ] }, { "id": "81711", "name": "", "equation": "hexanedioate + glutaryl-CoA = hexanedioyl-CoA + glutarate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "81711", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81711" } ] }, { "id": "81715", "name": "", "equation": "itaconate + glutaryl-CoA = itaconyl-CoA + glutarate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "81715", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81715" } ] }, { "id": "81723", "name": "", "equation": "3-hydroxy-3-methylglutarate + glutaryl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + glutarate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBX3-1" ], "evidence": [ { "id": "81723", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81723" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZBX3", "gene_name": "SUGCT", "activity": [ { "ec_number": "2.8.3.13", "activity": "3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate.", "evidence": [ { "id": "A0A8V0ZBX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3" } ] }, { "ec_number": "2.8.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZBX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBX3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.8.3.13", "ec_name": "3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate.", "evidence": [ { "id": "2.8.3.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.13" }, { "id": "2.8.3.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.8.3.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBZ5-1", "uniprot_ac": "A0A8V0ZBZ5", "uniprot_id": "A0A8V0ZBZ5_CHICK", "mass": { "chemical_mass": 317410.0, "monoisotopic_mass": 317410.0 }, "refseq": { "ac": "XP_420887", "name": "Alstrom syndrome protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420887" }, "gene_names": [ { "name": "ALMS1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ] }, { "name": "ALMS1", "type": "synonym", "evidence": [ { "id": "XP_420887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420887" } ] } ], "protein_names": [ { "name": "ALMS1 centrosome and basal body associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5/entry#names_and_taxonomy" } ] }, { "name": "Alstrom syndrome protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420887" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420887.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420887" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALMS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5", "locus": {} } ], "crossref": [ { "id": "422949", "url": "https://www.ncbi.nlm.nih.gov/gene/422949", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HPIHHST", "url": "https://omabrowser.org/oma/group/HPIHHST/", "database": 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"R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YY89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGEEVEDEEEEQSVPPIATTPPRRSWREESLSQSSSETQASAASGISLGEAIRQRTAVNQEIDSWYQLPGEVDASRLTAASETKLGLASDRNDLTEFPTLEEGVLPSAETSRRQHPEDTVHGLLLDIQDSQLSPCLPLLMYSTPGQRILDETLFQQSERDFIHLRGVPDVSGASEQHSNRLHVAEAAWLTDVETPSDAPSDCYSLSQHPLSFRQTEPGDASYLSQQASRFSERLLMNKKASEDCRNDTNEKSSIPHMGDKAMNQTEASLAKQTCGTSAEDACFTCNNNVLAPVFELSEKEKELLRRDEFSSSENSSCKAALTKNSGKSEREMQMEKVKMAESESEGCLRHPERLEKEKAPELGSSKALSDDLKKDSCKNSGAQGMFSAKTSEITRESKECRVGLNDFGSMKFVAVTNELQGAFLDREAKQGVREEELSPIVPSSSDSAPKQLAVTNVESPSCTENAQVEVQPGVRKAELTISDVSIERGHKVTDISPSLNFTVDDGSFFRHFSHPSYQSTPGILLKNVKTDPGAHVIKSDVHAPPLCLNEDNSGNSLSSTPTSGEKQRSLQCAQKENNKHFDSLKLKYPHTGRIQSLPSLYFMEKVDTWNMSQPENMSDALASRDQSVISHRKKAYSVVARSANNILSMQNSSRNPEVHVAAPSGETHSLENIHFHDKISERVHPLTRSQSDNSVHVASKNNSQTDVVQPVNREAMQPLEGKSNVSGVPENRLGGSLIHKLTTEIASLSVDKGAEGSSVGQSSYPNASIPSERVAHLIKEDGNSPTDDQKRCDGLENPRLPHNLDIGHVSVDNVGDISPDSLNLPACSGESSHGALGSPVITRHFFTSAGDDNFIPSSTATVLETPEKEELNIEERIPIYLRNLGIDQSPGTILTPFVPRGPIREVEFSPSDLRTLKDSTDTLTRTIQQPQGDLLTAVDVIQTSFNSGTSTVSISIPMNSETDSDTFSPRELSPRFSIPFGEKPKSQCTMSCHKVEATTPLSTQWETECSVVSKLAEPSQHLQTVSPDCHSNRESPMLVAKGVQDLLAKKELKDMSGSSQRWTASSSAGVKDEQGRGSQTSSEGSEKNKGQESDYLIGSGALQEIRKLLAEAENIAGSWHDPVFSNASSSETESSPVQIEKEDGTKDSELVKDSIAPLQKVMSWAESMNQRSIHEGSITKPQDSCKDDLKWERSFDGGLCSREDVVEMTREFRTGKSVGRSEPEGCSSVTTDRNLPAVVAVAQSSANSEFSTERPSELGSPSPSEPQGSVINVPASFQSKLSKANVAVSKAGGIRESSGSSSGDSLAAHVKNLLGNPLMLLGRTADISGGFQSMMSKTSAAGSKAEGVQESHGSSSGDSLAARVKNLLGDPSESLGSTTDVPGGFQSVLSKPSAAGSKAGGVQESDGSSSADSLAARVKSLLRNGSPLMPATPILRSSDEEERKARAWVKLKLANQSQEAVLDLSEEDRQRIEEIKAELLLSAKKSGQAKGTRSYSSLAASVYSCNQEADEEHSKASSDKRFHSDSQTQAFRTKELLEPSLQHVVPLYRAELSDCCLLKNTQLKSLSTAEPPTCSQHQAIASSRSGCVGLHLPLEKQQDTRVMSFAAASDAQTAKVPSPAQKKLSFPKCSEEMSKQITSITFSSRRRFQSPLTSVVLDGFFSGDDLDEIMPLEMDSVTTEEQSHGKQHWERSETCPLSGSAPAGSQSNEIAFTADKDRFHDVSADGNRAGAYQETDCLSDREPVTVCADERQTPSAKNLDTPSQDVTELDRHSARLLGLDCDRRFSQGMKGLHESHSISSYQQEKSSPTSHIQLCESLEGSDPAIQTDLPKDHGKLLEEEKCPSDAVPFIQKEVSGEQIDAHQHSDEILPTMSPSSPIKKVLSCVHITLSPKCNNSELHRDLNTENEMRLEDKLEVNSQPVPLKTPETLLQADPKLPTADLIPEDQRCSSFPVPSSDPCSVFSSVPSTAGQELLLHGSEKLQAMSSGGCSLKNICSCTDPAKSRKSTSDATTQITTESPGKTTFSAEIYVNSQDIESSAHQSSTQKAKEFPQNTTSSLNRTSSFPRQGAGQPLLLPYKPSGSTEMYYVPYLKAGAKISPLGSENNGSNDALPPGLPANVLGIQDDKPPDTTAIKHKEGVCSERAKPKLAWAEEQMIAQEGAPGSHRLKSVNATHSVFKSAQFYLHHPVPTCENYLLSNSELSEDSSGVGHTGISSSTVIQNRKKAHRHRRVFSAHHKKDGEREFFPLTAEADYSKNEDLNVDTSLNNETPGEELLQRGRREADQMAACSQMSNLRENVVKDLPLRQRTHSAGSLDELWVKFLERQKRYQQHHFRRNGELTLVERLDRLARVLQNPIRYTLIPAKSERSASENTSEVKEQEKIRLPEKSMAESTLGPHAARVKERPRINCRERSFVELRKDRSGEKVTCHTNEISEHRQYLDTCSDTCSETRLSKDLCTTISSTISESDAVTQTDIETTTQTEVSSSVSTIDTARLVRAFGHRRVQVSPRLSQLYHTIHQQKSRSEKWDEESSGVRDVEHPKVASERHRKQKETQKALDPALTSSGSWGPSSALSNKRRARMLNKGIQAGDLEIVNGATKKNTRDVGVTFPTPRSIQPNQRPRDPWHRVDGIFGESDGMVTDHQAAGSKGKQKGQPGNFFMEKRTKRSRLHLPQGISWFVQAEDLKFESRKENRSNSIPGPGSSWFEPFTTTKPWREPLREKNFQEQQYSKVTQSAVPERDAETRPTRPTVKLTLQEALAVHRPDFISRSGERVKHLKLVMEERRIQSALQSEQEELFNPPEKRKGYRNASHVLPGRGHLIKEKRRAIPKSEMVQRSKRIYEQLPEVQKKREEEKRKSEYNSYRLKAQLYKMKITNRVLGRKVPWN", "length": 2887, "header": "tr|A0A8V0ZBZ5-1|A0A8V0ZBZ5_CHICK Isoform 1 of ALMS1 centrosome and basal body associated protein OS=Gallus gallus OX=9031 GN=ALMS1 PE=4 SV=1 CANONICAL=A0A8V0ZBZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5/entry#A0A8V0YY89-1", "sequence": { "sequence": "MEPGEEVEDEEEEQSVPPIATTPPRRSWREESLSQSSSETQASAASGISLGEAIRQRTAVNQEIDSWYQLPGEVDASRLTAASETKLGLASDRNDLTEFPTLEEGVLPSAETSRRQHPEDTVHGLLLDIQDSQLSPCLPLLMYSTPGQRILDETLFQQSERDFIHLRGVPDVSGASEQHSNRLHVAEAAWLTDVETPSDAPSDCYSLSQHPLSFRQTEPGDASYLSQQASRFSERLLMNKKASEDCRNDTNEKSSIPHMGDKAMNQTEASLAKQTCGTSAEDACFTCNNNVLAPVFELSEKEKELLRRDEFSSSENSSCKAALTKNSGKSEREMQMEKVKMAESESEGCLRHPERLEKEKAPELGSSKALSDDLKKDSCKNSGAQGMFSAKTSEITRESKECRVGLNDFGSMKFVAVTNELQGAFLDREAKQGVREEELSPIVPSSSDSAPKQLAVTNVESPSCTENAQVEVQPGVRKAELTISDVSIERGHKVTDISPSLNFTVDDGSFFRHFSHPSYQSTPGILLKNVKTDPGAHVIKSDVHAPPLCLNEDNSGNSLSSTPTSGEKQRSLQCAQKENNKHFDSLKLKYPHTGRIQSLPSLYFMEKVDTWNMSQPENMSDALASRDQSVISHRKKAYSVVARSANNILSMQNSSRNPEVHVAAPSGETHSLENIHFHDKISERVHPLTRSQSDNSVHVASKNNSQTDVVQPVNREAMQPLEGKSNVSGVPENRLGGSLIHKLTTEIASLSVDKGAEGSSVGQSSYPNASIPSERVAHLIKEDGNSPTDDQKRCDGLENPRLPHNLDIGHVSVDNVGDISPDSLNLPACSGESSHGALGSPVITRHFFTSAGDDNFIPSSTATVLETPEKEELNIEERIPIYLRNLGIDQSPGTILTPFVPRGPIREVEFSPSDLRTLKDSTDTLTRTIQQPQGDLLTAVDVIQTSFNSGTSTVSISIPMNSETDSDTFSPRELSPRFSIPFGEKPKSQCTMSCHKVEATTPLSTQWETECSVVSKLAEPSQHLQTVSPDCHSNRESPMLVAKGVQDLLAKKELKDMSGSSQRWTASSSAGVKDEQGRGSQTSSEGSEKNKGQESDYLIGSGALQEIRKLLAEAENIAGSWHDPVFSNASSSETESSPVQIEKEDGTKDSELVKDSIAPLQKVMSWAESMNQRSIHEGSITKPQDSCKDDLKWERSFDGGLCSREDVVEMTREFRTGKSVGRSEPEGCSSVTTDRNLPAVVAVAQSSANSEFSTERPSELGSPSPSEPQGSVINVPASFQSKLSKANVAVSKAGGIRESSGSSSGDSLAAHVKNLLGNPLMLLGRTADISGGFQSMMSKTSAAGSKAEGVQESHGSSSGDSLAARVKNLLGDPSESLGSTTDVPGGFQSVLSKPSAAGSKAGGVQESDGSSSADSLAARVKSLLRNGSPLMPATPILRSSDEEERKARAWVKLKLANQSQEAVLDLSEEDRQRIEEIKAELLLSAKKSGQAKGTRSYSSLAASVYSCNQEADEEHSKASSDKRFHSDSQTQAFRTKELLEPSLQHVVPLYRAELSDCCLLKNTQLKSLSTAEPPTCSQHQAIASSRSGCVGLHLPLEKQQDTRVMSFAAASDAQTAKVPSPAQKKLSFPKCSEEMSKQITSITFSSRRRFQSPLTSVVLDGFFSGDDLDEIMPLEMDSVTTEEQSHGKQHWERSETCPLSGSAPAGSQSNEIAFTADKDRFHDVSADGNRAGAYQETDCLSDREPVTVCADERQTPSAKNLDTPSQDVTELDRHSARLLGLDCDRRFSQGMKGLHESHSISSYQQEKSSPTSHIQLCESLEGSDPAIQTDLPKDHGKLLEEEKCPSDAVPFIQKEVSGEQIDAHQHSDEILPTMSPSSPIKKVLSCVHITLSPKCNNSELHRDLNTENEMRLEDKLEVNSQPVPLKTPETLLQADPKLPTADLIPEDQRCSSFPVPSSDPCSVFSSVPSTAGQELLLHGSEKLQAMSSGGCSLKNICSCTDPAKSRKSTSDATTQITTESPGKTTFSAEIYVNSQDIESSAHQSSTQKAKEFPQNTTSSLNRTSSFPRQGGQPLLLPYKPSGSTEMYYVPYLKAGAKISPLGSENNGSNDALPPGLPANVLGIQDDKPPDTTAIKHKEGVCSERAKPKLAWAEEQMIAQEGAPGSHRLKSVNATHSVFKSAQFYLHHPVPTCENYLLSNSELSEDSSGVGHTGISSSTVIQNRKKAHRHRRVFSAHHKKDGEREFFPLTAEADYSKNEDLNVDTSLNNETPGEELLQRGRREADQMAACSQMSNLRENVVKDLPLRQRTHSAGSLDELWVKFLERQKRYQQHHFRRNGELTLVERLDRLARVLQNPIRYTLIPAKSERSASENTSEVKEQEKIRLPEKSMAESTLGPHAARVKERPRINCRERSFVELRKDRSGEKVTCHTNEISEHRQYLDTCSDTCSETRLSKDLCTTISSTISESDAVTQTDIETTTQTEVSSSVSTIDTARLVRAFGHRRVQVSPRLSQLYHTIHQQKSRSEKWDEESSGVRDVEHPKVASERHRKQKETQMLNPSQKVFLSSSFCLFLKQSSSCHLVAEGIGSGFDKQWFLGTKLSSQ", "length": 2603, "header": "tr|A0A8V0YY89-1|A0A8V0ZBZ5_CHICK Computationally mapped isoform of ALMS1 centrosome and basal body associated protein OS=Gallus gallus OX=9031 GN=ALMS1 PE=4 SV=1 CANONICAL=A0A8V0ZBZ5-1" }, "locus": { "chromosome": "4", "start_pos": 89241083, "end_pos": 89199942, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043727.1", "url": "https://www.ensembl.org/id/ENSGALT00010043727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026016.1", "url": "https://www.ensembl.org/id/ENSGALP00010026016.1" } ] } }, { "isoform_ac": "A0A8V0ZBZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5/entry#A0A8V0ZBZ5-1", "sequence": { "sequence": "MEPGEEVEDEEEEQSVPPIATTPPRRSWREESLSQSSSETQASAASGISLGEAIRQRTAVNQEIDSWYQLPGEVDASRLTAASETKLGLASDRNDLTEFPTLEEGVLPSAETSRRQHPEDTVHGLLLDIQDSQLSPCLPLLMYSTPGQRILDETLFQQSERDFIHLRGVPDVSGASEQHSNRLHVAEAAWLTDVETPSDAPSDCYSLSQHPLSFRQTEPGDASYLSQQASRFSERLLMNKKASEDCRNDTNEKSSIPHMGDKAMNQTEASLAKQTCGTSAEDACFTCNNNVLAPVFELSEKEKELLRRDEFSSSENSSCKAALTKNSGKSEREMQMEKVKMAESESEGCLRHPERLEKEKAPELGSSKALSDDLKKDSCKNSGAQGMFSAKTSEITRESKECRVGLNDFGSMKFVAVTNELQGAFLDREAKQGVREEELSPIVPSSSDSAPKQLAVTNVESPSCTENAQVEVQPGVRKAELTISDVSIERGHKVTDISPSLNFTVDDGSFFRHFSHPSYQSTPGILLKNVKTDPGAHVIKSDVHAPPLCLNEDNSGNSLSSTPTSGEKQRSLQCAQKENNKHFDSLKLKYPHTGRIQSLPSLYFMEKVDTWNMSQPENMSDALASRDQSVISHRKKAYSVVARSANNILSMQNSSRNPEVHVAAPSGETHSLENIHFHDKISERVHPLTRSQSDNSVHVASKNNSQTDVVQPVNREAMQPLEGKSNVSGVPENRLGGSLIHKLTTEIASLSVDKGAEGSSVGQSSYPNASIPSERVAHLIKEDGNSPTDDQKRCDGLENPRLPHNLDIGHVSVDNVGDISPDSLNLPACSGESSHGALGSPVITRHFFTSAGDDNFIPSSTATVLETPEKEELNIEERIPIYLRNLGIDQSPGTILTPFVPRGPIREVEFSPSDLRTLKDSTDTLTRTIQQPQGDLLTAVDVIQTSFNSGTSTVSISIPMNSETDSDTFSPRELSPRFSIPFGEKPKSQCTMSCHKVEATTPLSTQWETECSVVSKLAEPSQHLQTVSPDCHSNRESPMLVAKGVQDLLAKKELKDMSGSSQRWTASSSAGVKDEQGRGSQTSSEGSEKNKGQESDYLIGSGALQEIRKLLAEAENIAGSWHDPVFSNASSSETESSPVQIEKEDGTKDSELVKDSIAPLQKVMSWAESMNQRSIHEGSITKPQDSCKDDLKWERSFDGGLCSREDVVEMTREFRTGKSVGRSEPEGCSSVTTDRNLPAVVAVAQSSANSEFSTERPSELGSPSPSEPQGSVINVPASFQSKLSKANVAVSKAGGIRESSGSSSGDSLAAHVKNLLGNPLMLLGRTADISGGFQSMMSKTSAAGSKAEGVQESHGSSSGDSLAARVKNLLGDPSESLGSTTDVPGGFQSVLSKPSAAGSKAGGVQESDGSSSADSLAARVKSLLRNGSPLMPATPILRSSDEEERKARAWVKLKLANQSQEAVLDLSEEDRQRIEEIKAELLLSAKKSGQAKGTRSYSSLAASVYSCNQEADEEHSKASSDKRFHSDSQTQAFRTKELLEPSLQHVVPLYRAELSDCCLLKNTQLKSLSTAEPPTCSQHQAIASSRSGCVGLHLPLEKQQDTRVMSFAAASDAQTAKVPSPAQKKLSFPKCSEEMSKQITSITFSSRRRFQSPLTSVVLDGFFSGDDLDEIMPLEMDSVTTEEQSHGKQHWERSETCPLSGSAPAGSQSNEIAFTADKDRFHDVSADGNRAGAYQETDCLSDREPVTVCADERQTPSAKNLDTPSQDVTELDRHSARLLGLDCDRRFSQGMKGLHESHSISSYQQEKSSPTSHIQLCESLEGSDPAIQTDLPKDHGKLLEEEKCPSDAVPFIQKEVSGEQIDAHQHSDEILPTMSPSSPIKKVLSCVHITLSPKCNNSELHRDLNTENEMRLEDKLEVNSQPVPLKTPETLLQADPKLPTADLIPEDQRCSSFPVPSSDPCSVFSSVPSTAGQELLLHGSEKLQAMSSGGCSLKNICSCTDPAKSRKSTSDATTQITTESPGKTTFSAEIYVNSQDIESSAHQSSTQKAKEFPQNTTSSLNRTSSFPRQGAGQPLLLPYKPSGSTEMYYVPYLKAGAKISPLGSENNGSNDALPPGLPANVLGIQDDKPPDTTAIKHKEGVCSERAKPKLAWAEEQMIAQEGAPGSHRLKSVNATHSVFKSAQFYLHHPVPTCENYLLSNSELSEDSSGVGHTGISSSTVIQNRKKAHRHRRVFSAHHKKDGEREFFPLTAEADYSKNEDLNVDTSLNNETPGEELLQRGRREADQMAACSQMSNLRENVVKDLPLRQRTHSAGSLDELWVKFLERQKRYQQHHFRRNGELTLVERLDRLARVLQNPIRYTLIPAKSERSASENTSEVKEQEKIRLPEKSMAESTLGPHAARVKERPRINCRERSFVELRKDRSGEKVTCHTNEISEHRQYLDTCSDTCSETRLSKDLCTTISSTISESDAVTQTDIETTTQTEVSSSVSTIDTARLVRAFGHRRVQVSPRLSQLYHTIHQQKSRSEKWDEESSGVRDVEHPKVASERHRKQKETQKALDPALTSSGSWGPSSALSNKRRARMLNKGIQAGDLEIVNGATKKNTRDVGVTFPTPRSIQPNQRPRDPWHRVDGIFGESDGMVTDHQAAGSKGKQKGQPGNFFMEKRTKRSRLHLPQGISWFVQAEDLKFESRKENRSNSIPGPGSSWFEPFTTTKPWREPLREKNFQEQQYSKVTQSAVPERDAETRPTRPTVKLTLQEALAVHRPDFISRSGERVKHLKLVMEERRIQSALQSEQEELFNPPEKRKGYRNASHVLPGRGHLIKEKRRAIPKSEMVQRSKRIYEQLPEVQKKREEEKRKSEYNSYRLKAQLYKMKITNRVLGRKVPWN", "length": 2887, "header": "tr|A0A8V0ZBZ5-1|A0A8V0ZBZ5_CHICK Isoform 1 of ALMS1 centrosome and basal body associated protein OS=Gallus gallus OX=9031 GN=ALMS1 PE=4 SV=1 CANONICAL=A0A8V0ZBZ5-1" }, "locus": { "chromosome": "4", "start_pos": 89241083, "end_pos": 89189850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043729.1", "url": "https://www.ensembl.org/id/ENSGALT00010043729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026017.1", "url": "https://www.ensembl.org/id/ENSGALP00010026017.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 522, "start_aa": "Thr", "end_pos": 522, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr522", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of centriole replication", "id": "GO:0046599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1457, "end_pos": 1459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1896, "end_pos": 1898, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2055, "end_pos": 2057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2061, "end_pos": 2063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2107, "end_pos": 2109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2173, "end_pos": 2175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2269, "end_pos": 2271, "annotation": 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"url": "https://www.rhea-db.org/rhea/36435" } ] }, { "id": "38691", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38691", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38691" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC49" }, { "id": "PF02121", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol transfer protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 258, "start_aa": "Ser", "end_aa": "Glu", 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"relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC93-1", "uniprot_ac": "A0A8V0ZC93", "uniprot_id": "A0A8V0ZC93_CHICK", "mass": { "chemical_mass": 47238.0, "monoisotopic_mass": 47238.0 }, "refseq": {}, "gene_names": [ { "name": "FBXL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93", "locus": { "chromosome": "2", "start_pos": 44541326, "end_pos": 44489327, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018157", "url": "https://www.ensembl.org/id/ENSGALG00010018157" } ] } } ], "crossref": [ { "id": "A0A8V0ZC93", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC93", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420722", "url": "https://www.ncbi.nlm.nih.gov/gene/420722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420722", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YYL0", "url": "https://www.orthodb.org/?gene=A0A8V0YYL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z593", "url": "https://www.orthodb.org/?gene=A0A8V0Z593", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5B7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5D2", "url": "https://www.orthodb.org/?gene=A0A8V0Z5D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6A3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6A8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC59", "url": "https://www.orthodb.org/?gene=A0A8V0ZC59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC78", "url": "https://www.orthodb.org/?gene=A0A8V0ZC78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC93", "url": "https://www.orthodb.org/?gene=A0A8V0ZC93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z593", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z593", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z593-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z593-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HVVVFSNNDEALINKKLPKELLLRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 425, "header": "tr|A0A8V0ZC93-1|A0A8V0ZC93_CHICK Isoform 1 of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0YYL0-1", "sequence": { "sequence": "ASLPPIGTSNGIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 412, "header": "tr|A0A8V0YYL0-1|A0A8V0ZC93_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44518168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043925.1", "url": "https://www.ensembl.org/id/ENSGALT00010043925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026129.1", "url": "https://www.ensembl.org/id/ENSGALP00010026129.1" } ] } }, { "isoform_ac": "A0A8V0Z593-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0Z593-1", "sequence": { "sequence": "ARTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 328, "header": "tr|A0A8V0Z593-1|A0A8V0Z593_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44525206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043878.1", "url": "https://www.ensembl.org/id/ENSGALT00010043878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026093.1", "url": "https://www.ensembl.org/id/ENSGALP00010026093.1" } ] } }, { "isoform_ac": "A0A8V0Z5B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0Z5B7-1", "sequence": { "sequence": "MGPGRGAAARQVFSNNDEALINKKLPKELLLRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 433, "header": "tr|A0A8V0Z5B7-1|A0A8V0ZC93_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44489502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043910.1", "url": "https://www.ensembl.org/id/ENSGALT00010043910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026118.1", "url": "https://www.ensembl.org/id/ENSGALP00010026118.1" } ] } }, { "isoform_ac": "A0A8V0Z5D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0Z5D2-1", "sequence": { "sequence": "MVFSNNDEALINKKLPKELLLRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 391, "header": "tr|A0A8V0Z5D2-1|A0A8V0ZC93_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44489431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043932.1", "url": "https://www.ensembl.org/id/ENSGALT00010043932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026133.1", "url": "https://www.ensembl.org/id/ENSGALP00010026133.1" } ] } }, { "isoform_ac": "A0A8V0Z6A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0Z6A3-1", "sequence": { "sequence": "MLYAFFRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 408, "header": "tr|A0A8V0Z6A3-1|A0A8V0ZC93_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44515639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043884.1", "url": "https://www.ensembl.org/id/ENSGALT00010043884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026097.1", "url": "https://www.ensembl.org/id/ENSGALP00010026097.1" } ] } }, { "isoform_ac": "A0A8V0Z6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0Z6A8-1", "sequence": { "sequence": "HLNIVVISLAPSATLIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 416, "header": "tr|A0A8V0Z6A8-1|A0A8V0ZC93_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44505707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043889.1", "url": "https://www.ensembl.org/id/ENSGALT00010043889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026102.1", "url": "https://www.ensembl.org/id/ENSGALP00010026102.1" } ] } }, { "isoform_ac": "A0A8V0ZC59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0ZC59-1", "sequence": { "sequence": "CFFFSGTFAQNCRNIEHLNLNGCTKITDSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 328, "header": "tr|A0A8V0ZC59-1|A0A8V0ZC59_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44527324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043871.1", "url": "https://www.ensembl.org/id/ENSGALT00010043871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026089.1", "url": "https://www.ensembl.org/id/ENSGALP00010026089.1" } ] } }, { "isoform_ac": "A0A8V0ZC78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0ZC78-1", "sequence": { "sequence": "MRSGGGSMRMRRWICNHNRAAVFSNNDEALINKKLPKELLLRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 443, "header": "tr|A0A8V0ZC78-1|A0A8V0ZC78_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44489981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043900.1", "url": "https://www.ensembl.org/id/ENSGALT00010043900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026110.1", "url": "https://www.ensembl.org/id/ENSGALP00010026110.1" } ] } }, { "isoform_ac": "A0A8V0ZC93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93/entry#A0A8V0ZC93-1", "sequence": { "sequence": "HVVVFSNNDEALINKKLPKELLLRIFSFLDIVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQTDIEGRVVENISKRCGGFLRQLSLRGCHVVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVAITNSSLKGLSEGCRNLEHLNLSWCDQITKDGIEALVKGCSGLKALFLRGCTQLEDEALKHIQNHCHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCNLTDASLTALGLNCPRLKILEAARCSQLTDAGFTLLARNCHELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLQVLELDNCLLITDVTLEHLENCHNLERIELYDCQQVTRAGIKRIRAHRPHVKVHAYFAPVTPPPSVGGSGQRLCRCCIIL", "length": 425, "header": "tr|A0A8V0ZC93-1|A0A8V0ZC93_CHICK Isoform 1 of F-box/LRR-repeat protein 2 OS=Gallus gallus OX=9031 GN=FBXL2 PE=4 SV=1 CANONICAL=A0A8V0ZC93-1" }, "locus": { "chromosome": "2", "start_pos": 44539505, "end_pos": 44491688, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043919.1", "url": "https://www.ensembl.org/id/ENSGALT00010043919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026125.1", "url": "https://www.ensembl.org/id/ENSGALP00010026125.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 406, "start_aa": "Thr", "end_pos": 406, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr406", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420722", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420722", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulatory subunit binding", "id": "GO:0036312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036312", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "regulation of defense response", "id": "GO:0031347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031347", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "host-mediated perturbation of viral RNA genome replication", "id": "GO:0044830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC93" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 57, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 406 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCI8-1", "uniprot_ac": "A0A8V0ZCI8", "uniprot_id": "A0A8V0ZCI8_CHICK", "mass": { "chemical_mass": 201338.0, "monoisotopic_mass": 201338.0 }, "refseq": { "ac": "XP_015150175", "name": "WD repeat-containing protein 90 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150175" }, "gene_names": [ { "name": "WDR90", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ] }, { "name": "WDR90", "type": "synonym", "evidence": [ { "id": "XP_015150175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150175" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 90", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 90 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015150175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150175" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150175.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150175" } ] }, { "annotation": "Microtubule-binding protein that plays a crucial role in ensuring inner core protein localization within the centriole core, as well as in maintaining the microtubule wall integrity and the overall centriole roundness and stability. Required for efficient primary cilium formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YYV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYV1#function" }, { "database": "UniProtKB", "id": "ARBA00060089", "url": "https://www.uniprot.org/uniprotkb/ARBA00060089#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8", "locus": { "chromosome": "14", "start_pos": 13133585, "end_pos": 13105340, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018259", "url": "https://www.ensembl.org/id/ENSGALG00010018259" } ] } } ], "crossref": [ { "id": "416407", "url": "https://www.ncbi.nlm.nih.gov/gene/416407", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416407", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416407", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YYV1", "url": "https://www.orthodb.org/?gene=A0A8V0YYV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z6M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCI8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150175", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YYV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAWQSPYLNVFKHFRVEEWKRSHKEGDVTTVMDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLPRKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFICGAAKGSLHDGKARASRRELVGAAPADTRWTCLVLDLHYVLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLFEPGVTLSEAHRASPACHGATPMPRDMAFPVPKGGKWHDHYDYIRFPPDGSRLPYDSIQRSCSSPVAGGHNSEEPLGQLPQPVTLTKAVRDRLSLIQQITSPKAMPHRCPAAAGSIPEVHLAAPEALRVGDQEAEDGTLRGMGDSMRSLAVSDGGIHVYAHQRSKQAAHATHSGSEEGVHGKGPGADAPTSGRASRCRSFLPDPILKLRKVIGFGGCSTKWALWTHNSSAVVYPCHAVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAQEGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGHGKTMVVVWNTAQVTHGGEVLVLARAHTDVDIQTLKIASFDDTRMVSCGRDSVRLWRVRNGVLRSCPVNLGEYHALEFTDLAFEEGHSAAREPDDRTLFICSRSGHVLEVDYKNVCVRSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSILAFSVDGVWKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYSCVAQKSQVLRVLGNVVARDAGSGPDALVLSGDSRLLAFVGPSKYVVTVMEACSLDELLRVDISILDLNSTALDSAVRICFAPVSRGELLVSTSSNRILVLDAKTGRLVREVSPVHKLSCSSLALSKDARYLLTAGDKVIKVWDYRMRFDINFQVYIGHSEPVYQVAFTPDQQHVISVGDAIFLWDFLAVPAERSPPALARSSKSPLLPAAEKSSEKLKDVSDVPRQTIPLPLLSSPPCLDVSSVHPAGCQSIFSESDREEEACLPGRIAQNGGKDASVLMAEPARSEELIVVRPKVRPESCRPPAPSANEPKETRSPKSQCCVRPDSYRHFTPRFKASVLPQSFSAPPAGNEVLKLRAVIGYNGNGRGNMVWDPDTGFFAYTCGCVIVVEDLHSGSQNHWLGHVEEISTLAVSHDAQALASASGKRDGDSHCQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDYNDQTLALWSTYTYELLSSTRISEPVHDVAFSPFSHREMACVGKGAIMFWLLEQHGADINLKVHRAPVPEVLGPVELTSLCYGADTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRCNRLVSGSNTKRIRLWAVGAMQELRLKGPKGRPSSVLLEHEITLDGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFSWEAESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVLQCTRKQYHDFGVEGGELWLATSSDRRVSVWASDWLKDKCELLDWLSFPAPASPEGLGSLPPSLAAFCPWEHGTLVYVGFGMQKEALFYSLRKKQVVEKISLPYFATSLSLSPAARFMAVGFSERLLRLQRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASHSAVLVWELLGA", "length": 1841, "header": "tr|A0A8V0ZCI8-1|A0A8V0ZCI8_CHICK Isoform 1 of WD repeat-containing protein 90 OS=Gallus gallus OX=9031 GN=WDR90 PE=3 SV=1 CANONICAL=A0A8V0ZCI8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8/entry#A0A8V0YYV1-1", "sequence": { "sequence": "MDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLPRKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFICGAAKGSLHDGKARASRRELVGAAPADTRWTCLVLDLHYVLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLFEPATPRKEEKKISTARAQGVTLSEAHRASPACHGATPMPRDMAFPVPKGGKWHDHYDYIRFPPDGSRLPYDSIQRSCSSPVAGGHNSEEPLGQLPQPVTLTKAVRDRLSLIQQITSPKAMPHRCPAAAGSIPEVHLAAPEALRVGDQEAEDGTLRGMGDSMRSLAVSDGGIHVYAHQRSKQAAHATHSGSEEGVHGKGPGADAPTSGRASRCRSFLPDPILKLRKVIGFGGCSTKWALWTHNSSAVVYPCHAVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAQEGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGHGKTMVVVWNTAQVTHGGEVLVLARAHTDVDIQTLKIASFDDTRMVSCGRDSVRLWRVRNGVLRSCPVNLGEYHALEFTDLAFEEGHSAAREPDDRTLFICSRSGHVLEVDYKNVCVRSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSILAFSVDGVWKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYSCVAQKSQVLRVLGNVVARDAGSGPDALVLSGDSRLLAFVGPSKYVVTVMEACSLDELLRVDISILDLNSTALDSAVRICFAPVSRGELLVSTSSNRILVLDAKTGRLVREVSPVHKLSCSSLALSKDARYLLTAGDKVIKVWDYRMRFDINFQVYIGHSEPVYQVAFTPDQQHVISVGDAIFLWDFLAVPAERSPPALARSSKSPLLPAAEKSSEKLKDVSDVPRQTIPLPLLSSPPCLDVSSVHPAGCQSIFSESDREEEACLPGRIAQNGGKDASVLMAEPARSEELIVVRPKVRPESCRPPAPSANEPKETRSPKSQCCVRPDSYRHFTPRFKASVLPQSFSAPPAGNEVLKLRAVIGYNGNGRGNMVWDPDTGFFAYTCGCVIVVEDLHSGSQNHWLGHVEEISTLAVSHDAQALASASGKRDGDSHCQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDYNDQTLALWSTYTYELLSSTRISEPVHDVAFSPFSHREMACVGKGAIMFWLLEQHGADINLKVHRAPVPEVLGPVELTSLCYGADTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRCNRLVSGSNTKRIRLWAVGAMQELRLKGPKGRPSSVLLEHEITLDGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFSWEAESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVLQCTRKQYHDFGVEGGELWLATSSDRRVSVWASDWLKDKCELLDWLSFPAPASPEGLGSLPPSLAAFCPWEHGTLVYVGFGMQKEALFYSLRKKQVVEKISLPYFATSLSLSPAARFMAVGFSERLLRLQRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASHSAVLVWELLGA", "length": 1824, "header": "tr|A0A8V0YYV1-1|A0A8V0ZCI8_CHICK Computationally mapped isoform of WD repeat-containing protein 90 OS=Gallus gallus OX=9031 GN=WDR90 PE=3 SV=1 CANONICAL=A0A8V0ZCI8-1" }, "locus": { "chromosome": "14", "start_pos": 13133373, "end_pos": 13106030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044093.1", "url": "https://www.ensembl.org/id/ENSGALT00010044093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026211.1", "url": "https://www.ensembl.org/id/ENSGALP00010026211.1" } ] } }, { "isoform_ac": "A0A8V0Z6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8/entry#A0A8V0Z6M1-1", "sequence": { "sequence": "MDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLPRKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFICGAAKGSLHDGKARASRRELVGAAPADTRWTCLVLDLHYVLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLFEPGVTLSEAHRASPACHGATPMPRDMAFPVPKGGKWHDHYDYIRFPPDGSRLPYDSIQRSCSSPVAGGHNSEEPLGQLPQPVTLTKAVRDRLSLIQQITSPKAMPHRCPAAAGSIPEVHLAAPEALRVGDQEAEDGTLRGMGDSMRSLAVSDGGIHVYAHQRSKQAAHATHSGSEESFLPDPILKLRKVIGFGGCSTKWALWTHNSSAVVYPCHAVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAQEGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGHGKTMVVVWNTAQVTHGGEVLVLARAHTDVDIQTLKIASFDDTRMVSCGRDSVRLWRVRNGVLRSCPVNLGEYHALEFTDLAFEEGHSAAREPDDRTLFICSRSGHVLEVDYKNVCVRSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSILAFSVDGVWKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYSCVAQKSQVLRVLGNVVARDAGSGPDALVLSGDSRLLAFVGPSKYVVTVMEACSLDELLRVDISILDLNSTALDSAVRICFAPVSRGELLVSTSSNRILVLDAKTGRLVREVSPVHKLSCSSLALSKDARYLLTAGDKVIKVWDYRMRFDINFQVYIGHSEPVYQVAFTPDQQHVISVGDAIFLWDFLAVPAERSPPALARSSKSPLLPAAEKSSEKLKDVSDVPRQTIPLPLLSSPPCLDVSSVHPAGCQSIFSESDREEEACLPGRIAQNGGKDASVLMAEPARSEELIVVRPKVRPESCRPPAPSANEPKETRSPKSQCCVRPDSYRHFTPRFKASVLPQSFSAPPAGNEVLKLRAVIGYNGNGRGNMVWDPDTGFFAYTCGCVIVVEDLHSGSQNHWLGHVEEISTLAVSHDAQALASASGKRDGDSHCQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDYNDQTLALWSTYTYELLSSTRISEPVHDVAFSPFSHREMACVGKGAIMFWLLEQHGADINLKVHRAPVPEVLGPVELTSLCYGADTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRCNRLVSGSNTKRIRLWAVGAMQELRLKGPKGRPSSVLLEHEITLDGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFSWEAESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVLQCTRKQYHDFGVEGGELWLATSSDRRVSVWASDWLKDKCELLDWLSFPAPASPEGLGSLPPSLAAFCPWEHGTLVYVGFGMQKEALFYSLRKKQVVEKISLPYFATSLSLSPAARFMAVGFSERLLRLQRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASHSAVLVWELLGA", "length": 1787, "header": "tr|A0A8V0Z6M1-1|A0A8V0ZCI8_CHICK Computationally mapped isoform of WD repeat-containing protein 90 OS=Gallus gallus OX=9031 GN=WDR90 PE=3 SV=1 CANONICAL=A0A8V0ZCI8-1" }, "locus": { "chromosome": "14", "start_pos": 13133373, "end_pos": 13106030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044105.1", "url": "https://www.ensembl.org/id/ENSGALT00010044105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026220.1", "url": "https://www.ensembl.org/id/ENSGALP00010026220.1" } ] } }, { "isoform_ac": "A0A8V0ZCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8/entry#A0A8V0ZCI8-1", "sequence": { "sequence": "MAAAWQSPYLNVFKHFRVEEWKRSHKEGDVTTVMDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLPRKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFICGAAKGSLHDGKARASRRELVGAAPADTRWTCLVLDLHYVLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLFEPGVTLSEAHRASPACHGATPMPRDMAFPVPKGGKWHDHYDYIRFPPDGSRLPYDSIQRSCSSPVAGGHNSEEPLGQLPQPVTLTKAVRDRLSLIQQITSPKAMPHRCPAAAGSIPEVHLAAPEALRVGDQEAEDGTLRGMGDSMRSLAVSDGGIHVYAHQRSKQAAHATHSGSEEGVHGKGPGADAPTSGRASRCRSFLPDPILKLRKVIGFGGCSTKWALWTHNSSAVVYPCHAVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAQEGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGHGKTMVVVWNTAQVTHGGEVLVLARAHTDVDIQTLKIASFDDTRMVSCGRDSVRLWRVRNGVLRSCPVNLGEYHALEFTDLAFEEGHSAAREPDDRTLFICSRSGHVLEVDYKNVCVRSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSILAFSVDGVWKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYSCVAQKSQVLRVLGNVVARDAGSGPDALVLSGDSRLLAFVGPSKYVVTVMEACSLDELLRVDISILDLNSTALDSAVRICFAPVSRGELLVSTSSNRILVLDAKTGRLVREVSPVHKLSCSSLALSKDARYLLTAGDKVIKVWDYRMRFDINFQVYIGHSEPVYQVAFTPDQQHVISVGDAIFLWDFLAVPAERSPPALARSSKSPLLPAAEKSSEKLKDVSDVPRQTIPLPLLSSPPCLDVSSVHPAGCQSIFSESDREEEACLPGRIAQNGGKDASVLMAEPARSEELIVVRPKVRPESCRPPAPSANEPKETRSPKSQCCVRPDSYRHFTPRFKASVLPQSFSAPPAGNEVLKLRAVIGYNGNGRGNMVWDPDTGFFAYTCGCVIVVEDLHSGSQNHWLGHVEEISTLAVSHDAQALASASGKRDGDSHCQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDYNDQTLALWSTYTYELLSSTRISEPVHDVAFSPFSHREMACVGKGAIMFWLLEQHGADINLKVHRAPVPEVLGPVELTSLCYGADTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRCNRLVSGSNTKRIRLWAVGAMQELRLKGPKGRPSSVLLEHEITLDGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFSWEAESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVLQCTRKQYHDFGVEGGELWLATSSDRRVSVWASDWLKDKCELLDWLSFPAPASPEGLGSLPPSLAAFCPWEHGTLVYVGFGMQKEALFYSLRKKQVVEKISLPYFATSLSLSPAARFMAVGFSERLLRLQRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASHSAVLVWELLGA", "length": 1841, "header": "tr|A0A8V0ZCI8-1|A0A8V0ZCI8_CHICK Isoform 1 of WD repeat-containing protein 90 OS=Gallus gallus OX=9031 GN=WDR90 PE=3 SV=1 CANONICAL=A0A8V0ZCI8-1" }, "locus": { "chromosome": "14", "start_pos": 13133373, "end_pos": 13105447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044115.1", "url": "https://www.ensembl.org/id/ENSGALT00010044115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026228.1", "url": "https://www.ensembl.org/id/ENSGALP00010026228.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416407", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416407", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI8", "url": 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"recommended", "evidence": [ { "id": "A0A8V0ZCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ] } ], "protein_names": [ { "name": "Ras and Rab interactor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2", "locus": { "chromosome": "3", "start_pos": 4363242, "end_pos": 4302881, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018351", "url": "https://www.ensembl.org/id/ENSGALG00010018351" } ] } } ], "crossref": [ { "id": "A0A8V0ZCX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421246", "url": "https://www.ncbi.nlm.nih.gov/gene/421246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQLQWNG", "url": "https://omabrowser.org/oma/group/SQLQWNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZB6", "url": "https://www.orthodb.org/?gene=A0A8V0YZB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZC8", "url": "https://www.orthodb.org/?gene=A0A8V0YZC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z607", "url": "https://www.orthodb.org/?gene=A0A8V0Z607", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZCV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YZB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z607", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z607", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z607-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z607-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGTAHSLKAEQHHNPPSQASPDPRGESATPRRRCAEGSGSGPREEAVLSGAAPPRAPARPAAGCCRRLRSLRAGCARAACLSRLQALWLVRQRLEEQSLGAVGYASLQLCFWFGYICFGSEFKAFTGVFPGTMSCLTMKAHCRDKRGSFFKLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 1025, "header": "tr|A0A8V0ZCX2-1|A0A8V0ZCX2_CHICK Isoform 1 of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0YZB6-1", "sequence": { "sequence": "MFSGYLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 845, "header": "tr|A0A8V0YZB6-1|A0A8V0ZCX2_CHICK Computationally mapped isoform of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4334890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044295.1", "url": "https://www.ensembl.org/id/ENSGALT00010044295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026351.1", "url": "https://www.ensembl.org/id/ENSGALP00010026351.1" } ] } }, { "isoform_ac": "A0A8V0YZC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0YZC8-1", "sequence": { "sequence": "MALGTAHSLKAEQHHNPPSQASPDPRGESATPRRRCAEGSGSGPREEAVLSGAAPPRAPARPAAGCCRRLRSLRAGCARAACLSRLQALWLVRQRLEEQSLGAVGYASLQLCFWFGYICFGSLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 994, "header": "tr|A0A8V0YZC8-1|A0A8V0ZCX2_CHICK Computationally mapped isoform of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4302945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044308.1", "url": "https://www.ensembl.org/id/ENSGALT00010044308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026361.1", "url": "https://www.ensembl.org/id/ENSGALP00010026361.1" } ] } }, { "isoform_ac": "A0A8V0Z607-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0Z607-1", "sequence": { "sequence": "MQLLESSWEEFKAFTGVFPGTMSCLTMKAHCRDKRGSFFKLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 912, "header": "tr|A0A8V0Z607-1|A0A8V0ZCX2_CHICK Computationally mapped isoform of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4303844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044312.1", "url": "https://www.ensembl.org/id/ENSGALT00010044312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026365.1", "url": "https://www.ensembl.org/id/ENSGALP00010026365.1" } ] } }, { "isoform_ac": "A0A8V0ZCV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0ZCV0-1", "sequence": { "sequence": "MVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 857, "header": "tr|A0A8V0ZCV0-1|A0A8V0ZCV0_CHICK Computationally mapped isoform of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4334420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044289.1", "url": "https://www.ensembl.org/id/ENSGALT00010044289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026347.1", "url": "https://www.ensembl.org/id/ENSGALP00010026347.1" } ] } }, { "isoform_ac": "A0A8V0ZCW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0ZCW2-1", "sequence": { "sequence": "MEKEFKAFTGVFPGTMSCLTMKAHCRDKRGSFFKLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 906, "header": "tr|A0A8V0ZCW2-1|A0A8V0ZCW2_CHICK Computationally mapped isoform of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4313493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044303.1", "url": "https://www.ensembl.org/id/ENSGALT00010044303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026357.1", "url": "https://www.ensembl.org/id/ENSGALP00010026357.1" } ] } }, { "isoform_ac": "A0A8V0ZCX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2/entry#A0A8V0ZCX2-1", "sequence": { "sequence": "MALGTAHSLKAEQHHNPPSQASPDPRGESATPRRRCAEGSGSGPREEAVLSGAAPPRAPARPAAGCCRRLRSLRAGCARAACLSRLQALWLVRQRLEEQSLGAVGYASLQLCFWFGYICFGSEFKAFTGVFPGTMSCLTMKAHCRDKRGSFFKLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 1025, "header": "tr|A0A8V0ZCX2-1|A0A8V0ZCX2_CHICK Isoform 1 of Ras and Rab interactor 2 OS=Gallus gallus OX=9031 GN=RIN2 PE=1 SV=1 CANONICAL=A0A8V0ZCX2-1" }, "locus": { "chromosome": "3", "start_pos": 4361512, "end_pos": 4302945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044314.1", "url": "https://www.ensembl.org/id/ENSGALT00010044314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026367.1", "url": "https://www.ensembl.org/id/ENSGALP00010026367.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 539, "start_aa": "Thr", "end_pos": 539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr539", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G8E0-1", "protein_name": "Ras and Rab interactor 2 isoform X1", "gene_name": "Rin2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDISLGNGLEPSETHSMVRHKDDGYSEDKDGKACPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQNQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 901 }, "evidence": [ { "id": "A0A8V0ZCX2", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LNS3-1", "protein_name": "Ras and Rab interactor 2", "gene_name": "Rin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPEVLRTFYVSCWQRGWGSEESPACSRASLGEMSAWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDVSLENGLEPSETYSMVRHKDGGYPEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVHHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTACRPGRSPPEPELELEVEMGTAGHAGGAPPRDAPGDCTRAPPPDSESQPPPCHGARQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGDDLTPS", "length": 935 }, "evidence": [ { "id": "A0A8V0ZCX2", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F662-1", "protein_name": "Ras and Rab interactor 2 isoform X1", "gene_name": "rin2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEMMMQSCLMDRSSSFFKLIDTFSTEISELKQEMVQPAREPETEILQGLEGEVSGLFLQSSACAGVPGVRDSGYDSLRRRMSMLDRLMQTHSVWLLLSLSDDEARHILQPQPAGSFVVRRCYKLQKKVISLRMDSDTLIVRDFPVKESQYTFSLEGSGISFADLFRLVAFCCISRDVLPFTLKLPEAIASAKTPTDLEEVAKLGKGFWDSELCNKNKSSVSGETACDGSKQRLKRSPAVPFTRTPSELECSQSNGALCFINPLFLQTHQSNPSPKKQEPSPGDEGGGSQHHHRALHRTGQQQGDSSVFCRKTPSKPHISVSRSESERSPPPRPPPPRFGSSRSAVLRKQKTMPETVCWIKTPQEKTSLLGRLGSSFISLSPSSSPPKKFSKPILVPSARNKNSSGLLDADGIRCHMALDDQTIEDAVSWSLAKLSSRNPTAMENGSPAHEHCSTGRERLSDISISTSSSDSLDFSHSFPLPMEASPSKTDRPTGDSSQEEEEDDGINLESDQEVPSPFKSKKQNSAGTFVLPRALRGQLRKMSDVLNSLMTPERRAIRKIVEQSRDKGTYFGCLVQDYVSFLQENRGCHTSGLELLQTLRQFMTQMKSYLLQSSELDPPIESLIPEDQIDQVMEKAMHKCVLKPLKPVIEAALRDFQLSSGTMQQLKENLLLAKAKQPQEMGVDGARPPDPVAIEKIRHKFNNMCKMYSPEKKVSLLLSVCKLIYTIMENNSGRMYGADDFLPMLTYVMAQCDMPELDTEIQYMMELLDPSLLHGEGGYYLTSAYGAMSLIKNFQEDQAARELSSETRNTLHQWHRRRTTQRTTPSVDDFQNYLRVALQDASSGCTAKTLQVQPYATTEDVCQICADKFKISDPENYALFLLTEETTQQLTLDTHPQKIKAELHSRPQPQIFYFVYRQIQNFPVLSEQLDDNTSAN", "length": 938 }, "evidence": [ { "id": "A0A8V0ZCX2", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D684-1", "protein_name": "Ras and Rab interactor 2", "gene_name": "Rin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAWTMGAQGLDKRGSFFKLIDTIASEIGELKREMVQTDISRENGLEPSETHSMVRHKDGGYSEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPLNSPPPHRPLPSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTARRPSRRSEPEPELELELEMGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGARQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGEDLTPS", "length": 903 }, "evidence": [ { "id": "A0A8V0ZCX2", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "positive regulation of vasculogenesis", "id": "GO:2001214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX2" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell-matrix adhesion via fibronectin", "id": "GO:1904906", "url": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE44-1", "uniprot_ac": "A0A8V0ZE44", "uniprot_id": "A0A8V0ZE44_CHICK", "mass": { "chemical_mass": 95554.0, "monoisotopic_mass": 95554.0 }, "refseq": {}, "gene_names": [ { "name": "MSLN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ] } ], "protein_names": [ { "name": "Mesothelin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#names_and_taxonomy" } ] }, { "name": "Pre-pro-megakaryocyte-potentiating factor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Membrane-anchored forms may play a role in cellular adhesion.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z0T1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0T1#function" }, { "database": "UniProtKB", "id": "ARBA00058732", "url": "https://www.uniprot.org/uniprotkb/ARBA00058732#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z889", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z889#function" }, { "database": "UniProtKB", "id": "A0A8V0Z894", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z894#function" }, { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSLN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZE44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE44", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0T1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6P3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z889", "url": "https://www.orthodb.org/?gene=A0A8V0Z889", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z894", "url": "https://www.orthodb.org/?gene=A0A8V0Z894", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE44", "url": "https://www.orthodb.org/?gene=A0A8V0ZE44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23412:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23412:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0T1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z889", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z889", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z889-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z889-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z894", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z894", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z894-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z894-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPLQLGFLLMLSWLGADAAPAGTYLCSSLALNETAACTSVRSLSSCCPTCSLRDRFVCYLSPSAVSNMSGDDALSLAQRINESCTLNTTLGRTKGKGAPSSLTTEELQVVSSLVRNFERFTPAVLRVLDQIAVGLSVSDIENKISGEDLEASIPILGKVRGWNADQSSAIINKLLSSGYQISSGQRLAKLGSLVAGLNSSTLRSLPPEVILEAIKLHEFVQQIEVLPSPLKRIFVEKISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS", "length": 871, "header": "tr|A0A8V0ZE44-1|A0A8V0ZE44_CHICK Isoform 1 of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#A0A8V0Z0T1-1", "sequence": { "sequence": "MSGDDALSLAQRINESCTLNTTLGRTKGKGAPSSLTTEELQVVSSLVRNFERFTPAVLRVLDQIAVGLSVSDIENKISGEDLEASIPILGKVRGWNADQSSAIINKLLSSGYQISSGQRLAKLGSLVAGLNSSTLRSLPPEVILEAIKLHEFVQQIEVLPSPLKRIFVEKISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNITILSPSWYRGHDAPPPACSASQFPDDVGLVLKIFPWIQHDEMDQCVTCSEPAGDSGPGGEGCSVQAGSCCVALCSLLGTFLFQINRKKK", "length": 717, "header": "tr|A0A8V0Z0T1-1|A0A8V0ZE44_CHICK Computationally mapped isoform of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "locus": { "chromosome": "14", "start_pos": 6017581, "end_pos": 6007244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044933.1", "url": "https://www.ensembl.org/id/ENSGALT00010044933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026836.1", "url": "https://www.ensembl.org/id/ENSGALP00010026836.1" } ] } }, { "isoform_ac": "A0A8V0Z6P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#A0A8V0Z6P3-1", "sequence": { "sequence": "MFMLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS", "length": 570, "header": "tr|A0A8V0Z6P3-1|A0A8V0ZE44_CHICK Computationally mapped isoform of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "locus": { "chromosome": "14", "start_pos": 6014785, "end_pos": 6007420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044903.1", "url": "https://www.ensembl.org/id/ENSGALT00010044903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026818.1", "url": "https://www.ensembl.org/id/ENSGALP00010026818.1" } ] } }, { "isoform_ac": "A0A8V0Z889-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#A0A8V0Z889-1", "sequence": { "sequence": "MHGGNNISFTTISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS", "length": 644, "header": "tr|A0A8V0Z889-1|A0A8V0ZE44_CHICK Computationally mapped isoform of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "locus": { "chromosome": "14", "start_pos": 6016039, "end_pos": 6007420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044914.1", "url": "https://www.ensembl.org/id/ENSGALT00010044914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026824.1", "url": "https://www.ensembl.org/id/ENSGALP00010026824.1" } ] } }, { "isoform_ac": "A0A8V0Z894-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#A0A8V0Z894-1", "sequence": { "sequence": "MCKHGWLGADAAPAGTYLCSSLALNETAACTSVRSLRDRFVCYLSPSAVSNMSGDDALSLAQRINESCTLNTTLGRTKGKGAPSSLTTEELQVVSSLVRNFERFTPAVLRVLDQIAVGLSVSDIENKISGEDLEASIPILGKVRGWNADQSSAIINKLLSSGYQISSGQRLAKLGSLVAGLNSSTLRSLPPEVILEAIKLHEFVQQIEVLPSPLKRIFVEKISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS", "length": 854, "header": "tr|A0A8V0Z894-1|A0A8V0ZE44_CHICK Computationally mapped isoform of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "locus": { "chromosome": "14", "start_pos": 6019309, "end_pos": 6007420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044921.1", "url": "https://www.ensembl.org/id/ENSGALT00010044921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026829.1", "url": "https://www.ensembl.org/id/ENSGALP00010026829.1" } ] } }, { "isoform_ac": "A0A8V0ZE44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44/entry#A0A8V0ZE44-1", "sequence": { "sequence": "MPPLQLGFLLMLSWLGADAAPAGTYLCSSLALNETAACTSVRSLSSCCPTCSLRDRFVCYLSPSAVSNMSGDDALSLAQRINESCTLNTTLGRTKGKGAPSSLTTEELQVVSSLVRNFERFTPAVLRVLDQIAVGLSVSDIENKISGEDLEASIPILGKVRGWNADQSSAIINKLLSSGYQISSGQRLAKLGSLVAGLNSSTLRSLPPEVILEAIKLHEFVQQIEVLPSPLKRIFVEKISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS", "length": 871, "header": "tr|A0A8V0ZE44-1|A0A8V0ZE44_CHICK Isoform 1 of Mesothelin OS=Gallus gallus OX=9031 GN=MSLN PE=3 SV=1 CANONICAL=A0A8V0ZE44-1" }, "locus": { "chromosome": "14", "start_pos": 6021330, "end_pos": 6007420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044926.1", "url": "https://www.ensembl.org/id/ENSGALT00010044926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026832.1", "url": "https://www.ensembl.org/id/ENSGALP00010026832.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEJ7-1", "uniprot_ac": "A0A8V0ZEJ7", "uniprot_id": "A0A8V0ZEJ7_CHICK", "mass": { "chemical_mass": 36508.0, "monoisotopic_mass": 36508.0 }, "refseq": {}, "gene_names": [ { "name": "ANKRD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes.", "evidence": [ { "database": "UniProtKB", "id": "F1NYV8", "url": "https://www.uniprot.org/uniprotkb/F1NYV8#function" }, { "database": "UniProtKB", "id": "ARBA00054908", "url": "https://www.uniprot.org/uniprotkb/ARBA00054908#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7", "locus": { "chromosome": "6", "start_pos": 20401373, "end_pos": 20410128, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020507", "url": "https://www.ensembl.org/id/ENSGALG00010020507" } ] } } ], "crossref": [ { "id": "A0A8V0ZEJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006491", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "378926", "url": "https://www.ncbi.nlm.nih.gov/gene/378926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:378926", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYDCGEH", "url": "https://omabrowser.org/oma/group/QYDCGEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEJ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZEJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NYV8", "url": "https://www.orthodb.org/?gene=F1NYV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24126:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24126:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZEJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYV8", "url": "https://www.uniprot.org/uniprotkb/F1NYV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYV8-1", "url": "https://www.uniprot.org/uniprotkb/F1NYV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGGCSGDVEDLPVTGKKTDDKESGSFLPEDFKTGEYEAAVKLEKQDDLRTASDHLSTQVDMAHGKEKKREAELKKKKLQERSKLESLEDLEKIIQLKKKKKCRKVKAPLLKEPEPEVITGPVDIAMFFRAALENKLPVIEKYLSDKGDPNVCDEYKRTALHRACSEGHLEVVKKLVEAGALLELKDMLESTALHWACRGGNLEIVKFLLDKGINRNARDKLRSTPLHVAVRTGQYDCAEHLIACEADLNAKDREGDTPMHDAVRLNRYKMVRLLILYGADLTIKNADGKTPMDLVLQWQNGTKELFNNLKNNSYKSAHLNKF", "length": 324, "header": "tr|A0A8V0ZEJ7-1|A0A8V0ZEJ7_CHICK Isoform 1 of Ankyrin repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ANKRD1 PE=4 SV=1 CANONICAL=A0A8V0ZEJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7/entry#A0A8V0ZEJ7-1", "sequence": { "sequence": "MPAGGCSGDVEDLPVTGKKTDDKESGSFLPEDFKTGEYEAAVKLEKQDDLRTASDHLSTQVDMAHGKEKKREAELKKKKLQERSKLESLEDLEKIIQLKKKKKCRKVKAPLLKEPEPEVITGPVDIAMFFRAALENKLPVIEKYLSDKGDPNVCDEYKRTALHRACSEGHLEVVKKLVEAGALLELKDMLESTALHWACRGGNLEIVKFLLDKGINRNARDKLRSTPLHVAVRTGQYDCAEHLIACEADLNAKDREGDTPMHDAVRLNRYKMVRLLILYGADLTIKNADGKTPMDLVLQWQNGTKELFNNLKNNSYKSAHLNKF", "length": 324, "header": "tr|A0A8V0ZEJ7-1|A0A8V0ZEJ7_CHICK Isoform 1 of Ankyrin repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ANKRD1 PE=4 SV=1 CANONICAL=A0A8V0ZEJ7-1" }, "locus": { "chromosome": "6", "start_pos": 20408713, "end_pos": 20403558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049554.1", "url": "https://www.ensembl.org/id/ENSGALT00010049554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029278.1", "url": "https://www.ensembl.org/id/ENSGALP00010029278.1" } ] } }, { "isoform_ac": "F1NYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7/entry#F1NYV8-1", "sequence": { "sequence": "MMTMKVEELVTGKKTDDKESGSFLPEDFKTGEYEAAVKLEKQDDLRTASDHLSTQVDMAHGKEKKREAELKKKKLQERSKLESLEDLEKIIQLKKKKKCRKVKAPLLKEPEPEVITGPVDIAMFFRAALENKLPVIEKYLSDKGDPNVCDEYKRTALHRACSEGHLEVVKKLVEAGALLELKDMLESTALHWACRGGNLEIVKFLLDKGINRNARDKLRSTPLHVAVRTGQYDCAEHLIACEADLNAKDREGDTPMHDAVRLNRYKMVRLLILYGADLTIKNADGKTPMDLVLQWQNGTKELFNNLKNNSYKSAHLNKF", "length": 319, "header": "tr|F1NYV8-1|A0A8V0ZEJ7_CHICK Computationally mapped isoform of Ankyrin repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ANKRD1 PE=4 SV=1 CANONICAL=A0A8V0ZEJ7-1" }, "locus": { "chromosome": "6", "start_pos": 20410066, "end_pos": 20403558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049558.1", "url": "https://www.ensembl.org/id/ENSGALT00010049558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029279.1", "url": "https://www.ensembl.org/id/ENSGALP00010029279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:378926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378926", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q15327-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMVLKVEELVTGKKNGNGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZEJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBX7-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMVLKVEELVTGKKKGNGDAGEFLPEDFRDGEYEAAVTLEKQEDLKTLPVHFVSLGEQQWKTEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYKKTKVPVVKEPEPEIVTEPVDVPMFLKAALENKLPVIEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGSLDVLKLLLNKGAKISARDKLLSTPLHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLVLHWQNGTKAIFDSLKENSYKASRIAAF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZEJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEJ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q865U8-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMVLKVEELVTGKKNGGGDAGEFLPEDFRDGEYEAAVTLEKQEDLKTLPAHFVSLGEQQWKIEKEREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEVITEPVDVPRFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLVLNWQNGTKAIFDSLKENSYKASRIATF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZEJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R560-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "Ankrd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMVFRVEELVTGKKNSNGSSGEFLPGEFRNGEYEAAVALEKQEDLKTLPANSVNLGEEQRKSEKVREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIITEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMDLVLHWQNGTKAIFDSLKENAYKNSRIATF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZEJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CR42-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "Ankrd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMVLRVEELVTGKKNSNGAAGEFLPGEFRNGEYEAAVALEKQEDLKTLPANSVKQGEEQRKSEKLREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIMTEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNADVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLKVKNCAGKTPMDLVLHWQSGTKAIFDSLKENAYKNSRIATF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZEJ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 23, "go_terms": [ { "name": "skeletal myofibril assembly", "id": "GO:0014866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014866", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ7" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PA74", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLAVQQQGLRWGAYVAGCQSVHSDFRGISGSCIAACAGLCTEALGCALQRALGHTSGCAAGHAPGPVPWCAPICVLSLALKHARGEMSKKERTRYISTELGMRQRLFVGVLTSKSTLGTLAVAVNRTLAHRLERLVYFTGTRGRKVPHGMTVVTHGDERPIWNMYQTVRYLLEHCVNDFDWFFLVRDDTYTEAHRINRLVAHLSIDTHLYLGRPEEFIGGDTEGRYCSGGFGYLLSRSLLLRLQQHLESCRNDILSSQPDEWLGRCIIDHTAVSCTEEHEGLRYQYFELGKNVDPEHETDLRFPSAFTVHPVLDPVQMYRLHKYFAQVELERTYQEIQQLQLEIQNASSLSADGDHSAAWPVGIPPPFQPKTRFEVLRWDYFTEDQVYACVDGSPKCELQGADLADVADVVATAMEELNRKYQPVLHVRKQQLVNGYRRFDPTRGMEYTLDLQVEVVTQKGHSRSVTKRVHLVRPLSEVEIIPMPYVTEASRINVILPLTAHERDHAARFLEAYAAAAFESSENAVLTFLFIYDPFEAQQVTQNDIFAPVKAQITEYERKYAEVKIPWISVKTDAPSQIKVMDIISKKHPVDTLFFVAGVGTEVTVDFLNRCRMNTINNWQVFFPIHFQGYNPAVAYHNQAPPATLDLLRDAGRFDRDVFHEACFYNADYMAARTRMAGDVQENEDILETLDIYDMFIKYSNLHVFRAVEPALLQHYRHQACNPRLSEEIYHRCVQSSLEGVGSRSQLAMVLFEQEQGNST", "length": 762, "header": "tr|A0A8V0ZC44-1|A0A8V0ZC44_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=CHPF PE=3 SV=1 CANONICAL=A0A8V0ZC44-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44/entry#A0A1D5PA74-1", "sequence": { "sequence": "MGVLPPPGSGSWVLAALACGPALAPWAQRFCPSRRTRYISTELGMRQRLFVGVLTSKSTLGTLAVAVNRTLAHRLERLVYFTGTRGRKVPHGMTVVTHGDERPIWNMYQTVRYLLEHCVNDFDWFFLVRDDTYTEAHRINRLVAHLSIDTHLYLGRPEEFIGGDTEGRYCSGGFGYLLSRSLLLRLQQHLESCRNDILSSQPDEWLGRCIIDHTAVSCTEEHEGLRYQYFELGKNVDPEHETDLRFPSAFTVHPVLDPVQMYRLHKYFAQVELERTYQEIQQLQLEIQNASSLSADGDHSAAWPVGIPPPFQPKTRFEVLRWDYFTEDQVYACVDGSPKCELQGADLADVADVVATAMEELNRKYQPVLHVRKQQLVNGYRRFDPTRGMEYTLDLQVEVVTQKGHSRSVTKRVHLVRPLSEVEIIPMPYVTEASRINVILPLTAHERDHAARFLEAYAAAAFESSENAVLTFLFIYDPFEAQQVTQNDIFAPVKAQITEYERKYAEVKIPWISVKTDAPSQIKVMDIISKKHPVDTLFFVAGVGTEVTVDFLNRCRMNTINNWQVFFPIHFQGYNPAVAYHNQAPPATLDLLRDAGRFDRDVFHEACFYNADYMAARTRMAGDVQENEDILETLDIYDMFIKYSNLHVFRAVEPALLQHYRHQACNPRLSEEIYHRCVQSSLEGVGSRSQLAMVLFEQEQGNST", "length": 704, "header": "tr|A0A1D5PA74-1|A0A8V0ZC44_CHICK Computationally mapped isoform of Hexosyltransferase OS=Gallus gallus OX=9031 GN=CHPF PE=3 SV=2 CANONICAL=A0A8V0ZC44-1" }, "locus": { "chromosome": "7", "start_pos": 21703556, "end_pos": 21701096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043837.1", "url": "https://www.ensembl.org/id/ENSGALT00010043837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026072.1", "url": "https://www.ensembl.org/id/ENSGALP00010026072.1" } ] } }, { "isoform_ac": "A0A8V0ZC44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44/entry#A0A8V0ZC44-1", "sequence": { "sequence": "MRLAVQQQGLRWGAYVAGCQSVHSDFRGISGSCIAACAGLCTEALGCALQRALGHTSGCAAGHAPGPVPWCAPICVLSLALKHARGEMSKKERTRYISTELGMRQRLFVGVLTSKSTLGTLAVAVNRTLAHRLERLVYFTGTRGRKVPHGMTVVTHGDERPIWNMYQTVRYLLEHCVNDFDWFFLVRDDTYTEAHRINRLVAHLSIDTHLYLGRPEEFIGGDTEGRYCSGGFGYLLSRSLLLRLQQHLESCRNDILSSQPDEWLGRCIIDHTAVSCTEEHEGLRYQYFELGKNVDPEHETDLRFPSAFTVHPVLDPVQMYRLHKYFAQVELERTYQEIQQLQLEIQNASSLSADGDHSAAWPVGIPPPFQPKTRFEVLRWDYFTEDQVYACVDGSPKCELQGADLADVADVVATAMEELNRKYQPVLHVRKQQLVNGYRRFDPTRGMEYTLDLQVEVVTQKGHSRSVTKRVHLVRPLSEVEIIPMPYVTEASRINVILPLTAHERDHAARFLEAYAAAAFESSENAVLTFLFIYDPFEAQQVTQNDIFAPVKAQITEYERKYAEVKIPWISVKTDAPSQIKVMDIISKKHPVDTLFFVAGVGTEVTVDFLNRCRMNTINNWQVFFPIHFQGYNPAVAYHNQAPPATLDLLRDAGRFDRDVFHEACFYNADYMAARTRMAGDVQENEDILETLDIYDMFIKYSNLHVFRAVEPALLQHYRHQACNPRLSEEIYHRCVQSSLEGVGSRSQLAMVLFEQEQGNST", "length": 762, "header": "tr|A0A8V0ZC44-1|A0A8V0ZC44_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=CHPF PE=3 SV=1 CANONICAL=A0A8V0ZC44-1" }, "locus": { "chromosome": "7", "start_pos": 21703556, "end_pos": 21698580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043839.1", "url": "https://www.ensembl.org/id/ENSGALT00010043839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026074.1", "url": "https://www.ensembl.org/id/ENSGALP00010026074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acetylgalactosaminyltransferase activity", "id": "GO:0008376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" }, { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1971487", "name": "Chondroitin polymerase complex transfers GalNAc to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RW56-1", "A0A8V0Z8G8-1", "A0A8V0YBC7-1", "A0A8V0ZC44-1" ], "evidence": [ { "id": "R-GGA-1971487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971487" } ] }, { "id": "R-GGA-1971491", "name": "Chondroitin polymerase complex transfers GlcA to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1L1RW56-1", "A0A8V0Z8G8-1", "A0A8V0YBC7-1", "A0A8V0ZC44-1" ], "evidence": [ { "id": "R-GGA-1971491", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971491" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1L1RW56", "gene_name": "CHPF2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A1L1RW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RW56" } ] } ] }, { "uniprot_ac": "A0A8V0YBC7", "gene_name": "CHSY3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YBC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC7" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G8", "gene_name": "CHSY1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0Z8G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G8" } ] } ] }, { "uniprot_ac": "A0A8V0ZC44", "gene_name": "CHPF", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZC44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC44" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 760, "end_pos": 762 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCN9-1", "uniprot_ac": "A0A8V0ZCN9", "uniprot_id": "A0A8V0ZCN9_CHICK", "mass": { "chemical_mass": 50925.0, "monoisotopic_mass": 50925.0 }, "refseq": {}, "gene_names": [ { "name": "ALDH3B2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ] } ], "protein_names": [ { "name": "Aldehyde dehydrogenase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALDH3B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZCN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR012394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCN9", "url": "https://www.orthodb.org/?gene=A0A8V0ZCN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZJU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43570:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43570:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9845614", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQPLEHPWQPTDGEAGTAGADDGGMSENPYAGLVSRLRAAWLSRRTRPLEYRVAQLEALGRFLEEKKQDILEATALDMRKPPFEAEFSEVLLCKNELNEALNNLSRWMKDKHVDKNLATQLDSAFIRKDPYGVVLIIGPWNYPIYLLLVPLIGAIAAGNCVIIKPSELTKNSEKLIEEVLPKYLDKDCFAVVTAGVEETTRLLENKFDYIFFTGSPSVGRIIMTAAAKHLTPVTLELGGKNPCYVSDTCDVQNVARRVVWGRFFNAGQTCIAPEYVLCSVEMQEKLIPALREAITEFYGSEPRNSPDFGRIVGDKQFRRVQALLSSGRVAIGGQTDEKERYIAPTVLVDVKPSDPAMQEEIFGPILIIITVANIDEAIDFINSRERPLVVYAFSSNSKEVNQVLERTSSGGFCGNDTLMHVTLTSLPFGGIALLTPSCALREGGPNSSALAHKTNPLVGCT", "length": 462, "header": "tr|A0A8V0ZCN9-1|A0A8V0ZCN9_CHICK Isoform 1 of Aldehyde dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH3B2 PE=1 SV=1 CANONICAL=A0A8V0ZCN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9/entry#A0A8V0ZCN9-1", "sequence": { "sequence": "MEQPLEHPWQPTDGEAGTAGADDGGMSENPYAGLVSRLRAAWLSRRTRPLEYRVAQLEALGRFLEEKKQDILEATALDMRKPPFEAEFSEVLLCKNELNEALNNLSRWMKDKHVDKNLATQLDSAFIRKDPYGVVLIIGPWNYPIYLLLVPLIGAIAAGNCVIIKPSELTKNSEKLIEEVLPKYLDKDCFAVVTAGVEETTRLLENKFDYIFFTGSPSVGRIIMTAAAKHLTPVTLELGGKNPCYVSDTCDVQNVARRVVWGRFFNAGQTCIAPEYVLCSVEMQEKLIPALREAITEFYGSEPRNSPDFGRIVGDKQFRRVQALLSSGRVAIGGQTDEKERYIAPTVLVDVKPSDPAMQEEIFGPILIIITVANIDEAIDFINSRERPLVVYAFSSNSKEVNQVLERTSSGGFCGNDTLMHVTLTSLPFGGIALLTPSCALREGGPNSSALAHKTNPLVGCT", "length": 462, "header": "tr|A0A8V0ZCN9-1|A0A8V0ZCN9_CHICK Isoform 1 of Aldehyde dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH3B2 PE=1 SV=1 CANONICAL=A0A8V0ZCN9-1" }, "locus": { "chromosome": "5", "start_pos": 505577, "end_pos": 498927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051992.1", "url": "https://www.ensembl.org/id/ENSGALT00010051992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031032.1", "url": "https://www.ensembl.org/id/ENSGALP00010031032.1" } ] } }, { "isoform_ac": "A0A8V0ZJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9/entry#A0A8V0ZJU3-1", "sequence": { "sequence": "MEQPLEHPWQPTDGEAGTAGADDGGMSENPYAGLVSRLRAAWLSRRTRPLEYRVAQLEALGRFLEEKKQDILEATALDMRKPPFEAEFSEVLLCKNELNEALNNLSRWMKDKHVDKNLATQLDSAFIRKDPYGVVLIIGPWNYPIYLLLVPLIGAIAAGNCVIIKPSELTKNSEKLIEEVLPKYLDKDCFAVVTAGVEETTRLLENKFDYIFFTGSPSVGRIIMTAAAKHLTPVTLELGGKNPCYVSDTCDVQNVARRVVWGRFFNAGQTCIAPEYVLCSVEMQEKLIPALREAITEFYGSEPRNSPDFGRIVGDKQFRRVQALLSSGRVAIGGQTDEKERYIAPTVLVDVKPSDPAMQEEIFGPILIIITVANIDEAIDFINSRERPLVVYAFSSNSKEVNQVLERTSSGGFCGNDTLMHVTLTSLPFGGIGFR", "length": 435, "header": "tr|A0A8V0ZJU3-1|A0A8V0ZJU3_CHICK Computationally mapped isoform of Aldehyde dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH3B2 PE=1 SV=1 CANONICAL=A0A8V0ZCN9-1" }, "locus": { "chromosome": "5", "start_pos": 505577, "end_pos": 500499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051979.1", "url": "https://www.ensembl.org/id/ENSGALT00010051979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031025.1", "url": "https://www.ensembl.org/id/ENSGALP00010031025.1" } ] } }, { "isoform_ac": "A0A8V0ZJV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9/entry#A0A8V0ZJV0-1", "sequence": { "sequence": "MEQPLEHPWQPTDGEAGTAGADDGGMSENPYAGLVSRLRAAWLSRRTRPLEYRVAQLEALGRFLEEKKQDILEATALDMRKATQLDSAFIRKDPYGVVLIIGPWNYPIYLLLVPLIGAIAAGNCVIIKPSELTKNSEKLIEEVLPKYLDKDCFAVVTAGVEETTRLLENKFDYIFFTGSPSVGRIIMTAAAKHLTPVTLELGGKNPCYVSDTCDVQNVARRVVWGRFFNAGQTCIAPEYVLCSVEMQEKLIPALREAITEFYGSEPRNSPDFGRIVGDKQFRRVQALLSSGRVAIGGQTDEKERYIAPTVLVDVKPSDPAMQEEIFGPILIIITVANIDEAIDFINSRERPLVVYAFSSNSKEVNQVLERTSSGGFCGNDTLMHVTLTSLPFGGIGSSGLGMYHGQFTFDTFTHHRGCLQRSTGLEPINTLRYPPLQHPQDGSGPHCHLS", "length": 450, "header": "tr|A0A8V0ZJV0-1|A0A8V0ZCN9_CHICK Computationally mapped isoform of Aldehyde dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH3B2 PE=1 SV=1 CANONICAL=A0A8V0ZCN9-1" }, "locus": { "chromosome": "5", "start_pos": 505577, "end_pos": 499896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051987.1", "url": "https://www.ensembl.org/id/ENSGALT00010051987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031030.1", "url": "https://www.ensembl.org/id/ENSGALP00010031030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", "id": "GO:0016620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016620", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "pmid": "" }, { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN9" }, { "id": "PF00171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aldehyde dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 432, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC45-1", "uniprot_ac": "A0A8V0ZC45", "uniprot_id": "A0A8V0ZC45_CHICK", "mass": { "chemical_mass": 13071.0, "monoisotopic_mass": 13071.0 }, "refseq": {}, "gene_names": [ { "name": "RPS21", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein eS21", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S21", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ38#function" }, { "database": "UniProtKB", "id": "ARBA00045746", "url": "https://www.uniprot.org/uniprotkb/ARBA00045746#function" }, { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45", "locus": { "chromosome": "20", "start_pos": 8275728, "end_pos": 8281014, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021346", "url": "https://www.ensembl.org/id/ENSGALG00010021346" } ] } } ], "crossref": [ { "id": "A0A8V0ZC45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC45", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC45", "url": "https://www.orthodb.org/?gene=A0A8V0ZC45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ38", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FFLCALKCLSLVFVPVNLCSYCSRVSLALTVYFYCHCLISFYLSIPCYLLPSSASNRIIGAKDHASIQINISEVDKVTGRVNGQFKTYAICGAIRRMGESDDSILRLAKNDGIVSKNF", "length": 118, "header": "tr|A0A8V0ZC45-1|A0A8V0ZC45_CHICK Isoform 1 of Small ribosomal subunit protein eS21 OS=Gallus gallus OX=9031 GN=RPS21 PE=1 SV=1 CANONICAL=A0A8V0ZC45-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45/entry#A0A8V0ZC45-1", "sequence": { "sequence": "FFLCALKCLSLVFVPVNLCSYCSRVSLALTVYFYCHCLISFYLSIPCYLLPSSASNRIIGAKDHASIQINISEVDKVTGRVNGQFKTYAICGAIRRMGESDDSILRLAKNDGIVSKNF", "length": 118, "header": "tr|A0A8V0ZC45-1|A0A8V0ZC45_CHICK Isoform 1 of Small ribosomal subunit protein eS21 OS=Gallus gallus OX=9031 GN=RPS21 PE=1 SV=1 CANONICAL=A0A8V0ZC45-1" }, "locus": { "chromosome": "20", "start_pos": 8279955, "end_pos": 8277644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051720.1", "url": "https://www.ensembl.org/id/ENSGALT00010051720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030852.1", "url": "https://www.ensembl.org/id/ENSGALP00010030852.1" } ] } }, { "isoform_ac": "A0A8V0ZQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45/entry#A0A8V0ZQ38-1", "sequence": { "sequence": "MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQINISEVDKVTGRVNGQFKTYAICGAIRRMGESDDSILRLAKNDGIVSKYVCLSSHSNICRGNFHVQIQISG", "length": 104, "header": "tr|A0A8V0ZQ38-1|A0A8V0ZC45_CHICK Computationally mapped isoform of Small ribosomal subunit protein eS21 OS=Gallus gallus OX=9031 GN=RPS21 PE=1 SV=1 CANONICAL=A0A8V0ZC45-1" }, "locus": { "chromosome": "20", "start_pos": 8280721, "end_pos": 8277761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051722.1", "url": "https://www.ensembl.org/id/ENSGALT00010051722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030853.1", "url": "https://www.ensembl.org/id/ENSGALP00010030853.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" }, { "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" }, { "name": "endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000461", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBL2-1", "uniprot_ac": "A0A8V0ZBL2", "uniprot_id": "A0A8V0ZBL2_CHICK", "mass": { "chemical_mass": 60571.0, "monoisotopic_mass": 60571.0 }, "refseq": {}, "gene_names": [ { "name": "SLC2A9L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC2A9L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4L4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBK0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBL2", "url": "https://www.orthodb.org/?gene=A0A8V0ZBL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23503:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23503:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "60372", "url": "https://www.rhea-db.org/rhea/60372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z4L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTSVRCVLGRGELVSVGLLGTSMVGASWLLGMFAELRGCCARDCWGWRRKTWVWKGSVQRLTCPLLSVTLLVSFGSSMLYGYNLAVVNSPAVHIKAFYNATWSQRYGHGLPPGPLTLLYSLTVSIFALGGLGGSLLVGMLVARYGRHGTLGRSALLVLLAGGLMAFSRQLAAPEMVIIGRAITGLHSGICLSVVPLYLGEIAPKNLRGFLGLLPSIFICLGVFCAQVLGLPELLGQDRYWPLFLAVVAIPASLQLLLLHCFPESPRFLLIERNDVCGSTEALRRFLGTSDVQEVLEEMKEEQRSLSLVQTVSVWQLLQERSVRWQTLSVAVVNVGMQLSGIDAIWFYTNTIFRNAGIPESQIPYTTVGTGAIEVVAGLIGCFTIEKLGRRPLIITGFCAMGTCLAGITGCLLLQAALPWMRYVAVACVVGIIAGFCMGPAGVPFLMTAELFTQSHRSAAYVLGGSLNWLCNFTIGFIFPFLQMSTGAFSYLVFCGVCLLVALYVYLIVPETKNKTFMEISRVFAARQPLAPLCHAGMLRLRGYGAVESSLEGSEHSLP", "length": 559, "header": "tr|A0A8V0ZBL2-1|A0A8V0ZBL2_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC2A9L PE=3 SV=1 CANONICAL=A0A8V0ZBL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2/entry#A0A8V0Z4L4-1", "sequence": { "sequence": "MGEKSQARGLPSSPHPQTDEKGTLQPSRDISGHIKAFYNATWSQRYGHGLPPGPLTLLYSLTVSIFALGGLGGSLLVGMLVARYGRHGTLGRSALLVLLAGGLMAFSRQLAAPEMVIIGRAITGLHSGICLSVVPLYLGEIAPKNLRGFLGLLPSIFICLGVFCAQVLGLPELLGQDRYWPLFLAVVAIPASLQLLLLHCFPESPRFLLIERNDVCGSTEALRRFLGTSDVQEVLEEMKEEQRSLSLVQTVSVWQLLQERSVRWQTLSVAVVNVGMQLSGIDAIWFYTNTIFRNAGIPESQIPYTTVGTGAIEVVAGLIGCFTIEKLGRRPLIITGFCAMGTCLAGITGCLLLQAALPWMRYVAVACVVGIIAGFCMGPAGVPFLMTAELFTQSHRSAAYVLGGSLNWLCNFTIGFIFPFLQMSTGAFSYLVFCGVCLLVALYVYLIVPETKNKTFMEISRVFAARQPLAPLCHAGMLRLRGYGAVESSLEGSEHSLP", "length": 498, "header": "tr|A0A8V0Z4L4-1|A0A8V0ZBL2_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC2A9L PE=3 SV=1 CANONICAL=A0A8V0ZBL2-1" }, "locus": { "chromosome": "6", "start_pos": 23619865, "end_pos": 23616038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043495.1", "url": "https://www.ensembl.org/id/ENSGALT00010043495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025859.1", "url": "https://www.ensembl.org/id/ENSGALP00010025859.1" } ] } }, { "isoform_ac": "A0A8V0ZBK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2/entry#A0A8V0ZBK0-1", "sequence": { "sequence": "MGEKSQARGLPSSPHPQTDEKGTLQPSRDISGRLTCPLLSVTLLVSFGSSMLYGYNLAVVNSPAVHIKAFYNATWSQRYGHGLPPGPLTLLYSLTVSIFALGGLGGSLLVGMLVARYGSVVPLYLGEIAPKNLRGFLGLLPSIFICLGVFCAQVLGLPELLGQDRYWPLFLAVVAIPASLQLLLLHCFPESPRFLLIERNDVCGSTEALRRFLGTSDVQEVLEEMKEEQRSLSLVQTVSVWQLLQERSVRWQTLSVAVVNVGMQLSGIDAIWFYTNTIFRNAGIPESQIPYTTVGTGAIEVVAGLIGCFTIEKLGRRPLIITGFCAMGTCLAGITGCLLLQAALPWMRYVAVACVVGIIAGFCMGPAGVPFLMTAELFTQSHRSAAYVLGGSLNWLCNFTIGFIFPFLQMSTGAFSYLVFCGVCLLVALYVYLIVPETKNKTFMEISRVFAARQPLAPLCHAGMLRLRGYGAVESSLEGSEHSLP", "length": 485, "header": "tr|A0A8V0ZBK0-1|A0A8V0ZBL2_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC2A9L PE=3 SV=1 CANONICAL=A0A8V0ZBL2-1" }, "locus": { "chromosome": "6", "start_pos": 23619865, "end_pos": 23616038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043488.1", "url": "https://www.ensembl.org/id/ENSGALT00010043488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025856.1", "url": "https://www.ensembl.org/id/ENSGALP00010025856.1" } ] } }, { "isoform_ac": "A0A8V0ZBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2/entry#A0A8V0ZBK6-1", "sequence": { "sequence": "MLYGYNLAVVNSPAVHIKAFYNATWSQRYGHGLPPGPLTLLYSLTVSIFALGGLGGSLLVGMLVARYGRHGTLGRSALLVLLAGGLMAFSRQLAAPEMVIIGRAITGLHSGICLSVVPLYLGEIAPKNLRGFLGLLPSIFICLGVFCAQVLGLPELLGQDRYWPLFLAVVAIPASLQLLLLHCFPESPRFLLIERNDVCGSTEGEGCPGGGTTCGCASSHAILTAHISHITQTFSPTELSHSIFPVPITVVSGHFPGSQGCAAPWLPHAMSMSSHPPAPTALRRFLGTSDVQEVLEEMKEEQRSLSLVQTVSVWQLLQERSVRWQTLSVAVVNVGMQLSGIDAIWFYTNTIFRNAGIPESQIPYTTVGTGAIEVVAGLIGCFTIEKLGRRPLIITGFCAMGTCLAGITGCLLLQAALPWMRYVAVACVVGIIAGFCMGPAGVPFLMTAELFTQSHRSAAYVLGGSLNWLCNFTIGFIFPFLQMSTGAFSYLVFCGVCLLVALYVYLIVPETKNKTFMEISRVFAARQPLAPLCHAGMLRLRGYGAVESSLEGSEHSLP", "length": 558, "header": "tr|A0A8V0ZBK6-1|A0A8V0ZBK6_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC2A9L PE=4 SV=1 CANONICAL=A0A8V0ZBL2-1" }, "locus": { "chromosome": "6", "start_pos": 23619419, "end_pos": 23616038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043497.1", "url": "https://www.ensembl.org/id/ENSGALT00010043497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025861.1", "url": "https://www.ensembl.org/id/ENSGALP00010025861.1" } ] } }, { "isoform_ac": "A0A8V0ZBL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2/entry#A0A8V0ZBL2-1", "sequence": { "sequence": "MHTSVRCVLGRGELVSVGLLGTSMVGASWLLGMFAELRGCCARDCWGWRRKTWVWKGSVQRLTCPLLSVTLLVSFGSSMLYGYNLAVVNSPAVHIKAFYNATWSQRYGHGLPPGPLTLLYSLTVSIFALGGLGGSLLVGMLVARYGRHGTLGRSALLVLLAGGLMAFSRQLAAPEMVIIGRAITGLHSGICLSVVPLYLGEIAPKNLRGFLGLLPSIFICLGVFCAQVLGLPELLGQDRYWPLFLAVVAIPASLQLLLLHCFPESPRFLLIERNDVCGSTEALRRFLGTSDVQEVLEEMKEEQRSLSLVQTVSVWQLLQERSVRWQTLSVAVVNVGMQLSGIDAIWFYTNTIFRNAGIPESQIPYTTVGTGAIEVVAGLIGCFTIEKLGRRPLIITGFCAMGTCLAGITGCLLLQAALPWMRYVAVACVVGIIAGFCMGPAGVPFLMTAELFTQSHRSAAYVLGGSLNWLCNFTIGFIFPFLQMSTGAFSYLVFCGVCLLVALYVYLIVPETKNKTFMEISRVFAARQPLAPLCHAGMLRLRGYGAVESSLEGSEHSLP", "length": 559, "header": "tr|A0A8V0ZBL2-1|A0A8V0ZBL2_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=SLC2A9L PE=3 SV=1 CANONICAL=A0A8V0ZBL2-1" }, "locus": { "chromosome": "6", "start_pos": 23621239, "end_pos": 23616038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043504.1", "url": "https://www.ensembl.org/id/ENSGALT00010043504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025866.1", "url": "https://www.ensembl.org/id/ENSGALP00010025866.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "fructose transmembrane transporter activity", "id": "GO:0005353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fructose import across plasma membrane", "id": "GO:1990539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" }, { "name": "dehydroascorbic acid transport", "id": "GO:0070837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60372", "name": "", "equation": "D-fructose(out) = D-fructose(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60372", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60372" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 513, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCC1-1", "uniprot_ac": "A0A8V0ZCC1", "uniprot_id": "A0A8V0ZCC1_CHICK", "mass": { "chemical_mass": 32738.0, "monoisotopic_mass": 32738.0 }, "refseq": {}, "gene_names": [ { "name": "BIN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ] } ], "protein_names": [ { "name": "Bridging integrator 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in cytokinesis and septation where it has a role in the localization of F-actin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM9#function" }, { "database": "UniProtKB", "id": "ARBA00059510", "url": "https://www.uniprot.org/uniprotkb/ARBA00059510#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZAU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBM2", "url": 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"id": "cd07590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107049508", "url": "https://www.ncbi.nlm.nih.gov/gene/107049508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZAU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZBM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBM9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIA5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47174:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47174:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZAU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRTAAALRVEAPNPPGQPLQPHSSDVGLPHGNNTGIPRIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 289, "header": "tr|A0A8V0ZCC1-1|A0A8V0ZCC1_CHICK Isoform 1 of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZAU8-1", "sequence": { "sequence": "MLTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 237, "header": "tr|A0A8V0ZAU8-1|A0A8V0ZCC1_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1430801, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047970.1", "url": "https://www.ensembl.org/id/ENSGALT00010047970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028321.1", "url": "https://www.ensembl.org/id/ENSGALP00010028321.1" } ] } }, { "isoform_ac": "A0A8V0ZBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZBM2-1", "sequence": { "sequence": "MGKAFIPLMDAGRVKRPPPAGLLLCCPPGSTARRWDLYEAAGSCNGPRVTRNAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 252, "header": "tr|A0A8V0ZBM2-1|A0A8V0ZBM2_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1445112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047964.1", "url": "https://www.ensembl.org/id/ENSGALT00010047964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028318.1", "url": "https://www.ensembl.org/id/ENSGALP00010028318.1" } ] } }, { "isoform_ac": "A0A8V0ZBM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZBM9-1", "sequence": { "sequence": "MSWWRGTSRGSMGSCSSECRPRRLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 243, "header": "tr|A0A8V0ZBM9-1|A0A8V0ZCC1_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1428202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047977.1", "url": "https://www.ensembl.org/id/ENSGALT00010047977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028323.1", "url": "https://www.ensembl.org/id/ENSGALP00010028323.1" } ] } }, { "isoform_ac": "A0A8V0ZBN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZBN4-1", "sequence": { "sequence": "MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLGLLLCCPPGSTARRWDLYEAAGSCNGPRVTRNAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 285, "header": "tr|A0A8V0ZBN4-1|A0A8V0ZBN4_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1428202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047989.1", "url": "https://www.ensembl.org/id/ENSGALT00010047989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028329.1", "url": "https://www.ensembl.org/id/ENSGALP00010028329.1" } ] } }, { "isoform_ac": "A0A8V0ZCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZCC1-1", "sequence": { "sequence": "MGRTAAALRVEAPNPPGQPLQPHSSDVGLPHGNNTGIPRIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 289, "header": "tr|A0A8V0ZCC1-1|A0A8V0ZCC1_CHICK Isoform 1 of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1428857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047996.1", "url": "https://www.ensembl.org/id/ENSGALT00010047996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028333.1", "url": "https://www.ensembl.org/id/ENSGALP00010028333.1" } ] } }, { "isoform_ac": "A0A8V0ZCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZCC8-1", "sequence": { "sequence": "MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQRSTVRPTPVLQKEEKGLSGAIQRHTAPYSAILCHTAPYSAILCHTAPYSAIQRHTVPYSAIQRHTVPCNAMQCHTAPYCAILCHVMPCSAILCHAVPCNAI", "length": 261, "header": "tr|A0A8V0ZCC8-1|A0A8V0ZCC8_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1476747, "end_pos": 1428202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048006.1", "url": "https://www.ensembl.org/id/ENSGALT00010048006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028338.1", "url": "https://www.ensembl.org/id/ENSGALP00010028338.1" } ] } }, { "isoform_ac": "A0A8V0ZIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1/entry#A0A8V0ZIA5-1", "sequence": { "sequence": "MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTKKLQKDMKKSTDADLAMSKAAVKISSDLLSNPLCEQDAAFLGVVTAFDTAMRRMDSFNQEKVNQIQKTVIEPLKNGCGAVWAAVSRRFGSVFPSLNMAVKRREQTLQEYRRLQAKVEKYEEKERSGPGLAKLHQAREELRPVRADFEAKNQQLLQEMPKFYSSRSDYFTPSFEALLRAQVVFYSEMRSIFGDLTAQIGRAALSDELRERENEGRLGELRALSIVGDD", "length": 265, "header": "tr|A0A8V0ZIA5-1|A0A8V0ZIA5_CHICK Computationally mapped isoform of Bridging integrator 3 OS=Gallus gallus OX=9031 GN=BIN3 PE=4 SV=1 CANONICAL=A0A8V0ZCC1-1" }, "locus": { "chromosome": "22", "start_pos": 1455562, "end_pos": 1428202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047986.1", "url": "https://www.ensembl.org/id/ENSGALT00010047986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028326.1", "url": "https://www.ensembl.org/id/ENSGALP00010028326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "actin cortical patch localization", "id": "GO:0051666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "unidimensional cell growth", "id": "GO:0009826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC1" }, { "id": "PS51021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAR", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 268, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE34-1", "uniprot_ac": "A0A8V0ZE34", "uniprot_id": "A0A8V0ZE34_CHICK", "mass": { "chemical_mass": 45371.0, "monoisotopic_mass": 45371.0 }, "refseq": { "ac": "XP_046798596", "name": "DNA repair protein RAD51 homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798596" }, "gene_names": [ { "name": "RAD51B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ] }, { "name": "RAD51B", "type": "synonym", "evidence": [ { "id": "XP_046798596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798596" } ] } ], "protein_names": [ { "name": "DNA repair protein RAD51 homolog 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#names_and_taxonomy" } ] }, { "name": "DNA repair protein RAD51 homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046798596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798596" } ] }, { "name": "RAD51 homolog B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#names_and_taxonomy" } ] }, { "name": "RAD51-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046798596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798596" } ] }, { "annotation": "Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TW39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW39#function" }, { "database": "UniProtKB", "id": "ARBA00053115", "url": "https://www.uniprot.org/uniprotkb/ARBA00053115#function" }, { "database": "UniProtKB", "id": "A0A3Q2ULG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2ULG9#function" }, { "database": "UniProtKB", "id": "A0A8V0Z897", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z897#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A5#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZE43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE43#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLH4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD51B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34", "locus": { "chromosome": "5", "start_pos": 27907959, "end_pos": 28267566, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020659", "url": "https://www.ensembl.org/id/ENSGALG00010020659" } ] } } ], "crossref": [ { "id": "A0A8V0ZE34", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE34", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009491", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009491", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19493", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19493", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769071", "url": "https://www.ncbi.nlm.nih.gov/gene/769071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769071", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHCQGHN", "url": "https://omabrowser.org/oma/group/IHCQGHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW39", "url": "https://www.orthodb.org/?gene=A0A3Q2TW39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2ULG9", "url": "https://www.orthodb.org/?gene=A0A3Q2ULG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z897", "url": "https://www.orthodb.org/?gene=A0A8V0Z897", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8A5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B0", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE34", "url": "https://www.orthodb.org/?gene=A0A8V0ZE34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE43", "url": "https://www.orthodb.org/?gene=A0A8V0ZE43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFF3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46456:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46456:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693579", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046798596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2ULG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2ULG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2ULG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2ULG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z897", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z897", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z897-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z897-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTAGGWETRLHRVQGIMATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 414, "header": "tr|A0A8V0ZE34-1|A0A8V0ZE34_CHICK Isoform 1 of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TW39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A3Q2TW39-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPELRDHSCQRKKLFFRHKISRGQTNFSYLDESDYHIVEQWPRDPSRPSVSSS", "length": 303, "header": "tr|A0A3Q2TW39-1|A0A8V0ZE34_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 28102231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049895.1", "url": "https://www.ensembl.org/id/ENSGALT00010049895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029469.1", "url": "https://www.ensembl.org/id/ENSGALP00010029469.1" } ] } }, { "isoform_ac": "A0A3Q2ULG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A3Q2ULG9-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPGEH", "length": 255, "header": "tr|A0A3Q2ULG9-1|A0A8V0ZE34_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 28208447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049887.1", "url": "https://www.ensembl.org/id/ENSGALT00010049887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029466.1", "url": "https://www.ensembl.org/id/ENSGALP00010029466.1" } ] } }, { "isoform_ac": "A0A8V0Z897-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0Z897-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPLSFLMLKNSVLEACW", "length": 267, "header": "tr|A0A8V0Z897-1|A0A8V0ZE34_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 28162515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049890.1", "url": "https://www.ensembl.org/id/ENSGALT00010049890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029467.1", "url": "https://www.ensembl.org/id/ENSGALP00010029467.1" } ] } }, { "isoform_ac": "A0A8V0Z8A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0Z8A5-1", "sequence": { "sequence": "MLGVQGIMATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 404, "header": "tr|A0A8V0Z8A5-1|A0A8V0ZE34_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249866, "end_pos": 27909347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049903.1", "url": "https://www.ensembl.org/id/ENSGALT00010049903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029472.1", "url": "https://www.ensembl.org/id/ENSGALP00010029472.1" } ] } }, { "isoform_ac": "A0A8V0Z8B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0Z8B0-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 397, "header": "tr|A0A8V0Z8B0-1|A0A8V0ZE34_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 27909347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049913.1", "url": "https://www.ensembl.org/id/ENSGALT00010049913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029477.1", "url": "https://www.ensembl.org/id/ENSGALP00010029477.1" } ] } }, { "isoform_ac": "A0A8V0ZE34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0ZE34-1", "sequence": { "sequence": "MHTAGGWETRLHRVQGIMATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 414, "header": "tr|A0A8V0ZE34-1|A0A8V0ZE34_CHICK Isoform 1 of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28250545, "end_pos": 27909347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049909.1", "url": "https://www.ensembl.org/id/ENSGALT00010049909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029474.1", "url": "https://www.ensembl.org/id/ENSGALP00010029474.1" } ] } }, { "isoform_ac": "A0A8V0ZE43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0ZE43-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 395, "header": "tr|A0A8V0ZE43-1|A0A8V0ZE43_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 27909347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049923.1", "url": "https://www.ensembl.org/id/ENSGALT00010049923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029484.1", "url": "https://www.ensembl.org/id/ENSGALP00010029484.1" } ] } }, { "isoform_ac": "A0A8V0ZFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0ZFF3-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQVIHS", "length": 356, "header": "tr|A0A8V0ZFF3-1|A0A8V0ZFF3_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 27914911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049899.1", "url": "https://www.ensembl.org/id/ENSGALT00010049899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029470.1", "url": "https://www.ensembl.org/id/ENSGALP00010029470.1" } ] } }, { "isoform_ac": "A0A8V0ZFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0ZFG6-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTEVILTNQITTSLSNGLAIPADLVSPAHDLSLSEVTGASGSGKKESACVTAALGNTWSHSVNTRLILQYHDLLTRQIVIAKSPVAPFSTFFYTVEKSGLVLQDGKNLSNLPWEGTNPALQTIQVRNTALGNALLKTTDETPGDTPSP", "length": 250, "header": "tr|A0A8V0ZFG6-1|A0A8V0ZFG6_CHICK Computationally mapped isoform of RAD51 paralog B OS=Gallus gallus OX=9031 GN=RAD51B PE=4 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 27909347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049917.1", "url": "https://www.ensembl.org/id/ENSGALT00010049917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029480.1", "url": "https://www.ensembl.org/id/ENSGALP00010029480.1" } ] } }, { "isoform_ac": "A0A8V0ZLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34/entry#A0A8V0ZLH4-1", "sequence": { "sequence": "MATKKLRRAKLSQELCERLSRYQITTCQDFLCLSLLELMKVTGESYRNVQKLLRKVSLACAPKMQTAYEMKVRRSINPSAAFLPTSLHSLDKVLHGGIPCGSLTELTSPPGCGKTQFCITMSVLATLPVSMGGLDGAVIYIDTESAFSAERLIEIAGNRFPTYFDSDEKLFCMTRSIHLYRELTCDSVLKRIKSLEEEIISKKIKLIIIDSVASVVRKEFDTKLQGNLAERSNFLARGASLLKYVAEEFSIPNGNLWMAPCSQKCLKIGNSRK", "length": 273, "header": "tr|A0A8V0ZLH4-1|A0A8V0ZLH4_CHICK Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Gallus gallus OX=9031 GN=RAD51B PE=3 SV=1 CANONICAL=A0A8V0ZE34-1" }, "locus": { "chromosome": "5", "start_pos": 28249680, "end_pos": 28165643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049893.1", "url": "https://www.ensembl.org/id/ENSGALT00010049893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029468.1", "url": "https://www.ensembl.org/id/ENSGALP00010029468.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769071", "resource": "KEGG Pathway" }, { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-5693579", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "resource": "Reactome", "description": "Homologous DNA Pairing and Strand Exchange" }, { "id": "R-GGA-5693616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "resource": "Reactome", "description": "Presynaptic phase of homologous DNA pairing and strand exchange" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U1U7-1", "protein_name": "DNA repair protein RAD51 homolog 2", "gene_name": "RAD51B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSKKLRRVGLSQELCDRLNRHHIITCQDFLCLSPLELMKMTGLSYQGVHDLLCLVSRACAPPMQTAYEIKTQRSAVPSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPIDMGGLEGAVVYIDTESAFSAERLVEMAESRFPRYFSTEEKLLLTVSKVHLYRELSCDEVLQRIESLEEEIISKGVKLVIIDSVASVVRKEFDTQLQGNMRERNKFLAREAASLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCMTAALGNTWSHSVNTRLILQYLGSEKRQILVAKSPLAPFTTFVYTIEKEGLVLQDQQRP", "length": 350 }, "evidence": [ { "id": "A0A8V0ZE34", "url": "https://omabrowser.org/oma/group/A0A8V0ZE34/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TZP0-1", "protein_name": "DNA repair protein RAD51 homolog 2", "gene_name": "RAD51B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGSERSLTSADWDTGPAPKVYLPPSLGYPLVPRVAEVLFLAAPGGMGSKKLRRVGLSQELCDRLNRHQIVTCQDFLCLSPLELMKMTGLSYQGVHELLCLVSRACAPQMQTAYEIKTQRCAAHSSAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFDTEEKLLLTSSKVHLYRELSCDEVLQRIESLEEEIISKGVKLVIIDSVASVVRKEFDTQLQGNVRERNKFLAREAASLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEVPRRRPQENILFPHLKTNKQEYFSLSWLPGLSQAKRRSKTDTKEIALGLQCNRFKKMVKSCSWQRDSYQLVPRQLFLNVKPKGERKQLMFLVFSLHSKADKESMEFFFLKFFTSE", "length": 445 }, "evidence": [ { "id": "A0A8V0ZE34", "url": "https://omabrowser.org/oma/group/A0A8V0ZE34/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LTU5-1", "protein_name": "DNA repair protein RAD51 homolog 2", "gene_name": "Rad51b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKKLRRAGLSQELCDRLCRYQIVNCQDFLNLSPLELMKVTGLSYRGVHELLHTVSKACAPQMQTAYELKTRRSAHLSPAFLSTTLGALDEALHGGVPCGSLTEVTGPPGCGKTQFCIMMSVLATLPTRLGGLEGAVLYIDTESAFTAERLVEIAESRFPQYFNTEEKLLLTSSRVHLCQELTCEGLLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLGKGASLLKYLSGEFSVPVILTNQITTHLSGALPSQADLVSPADDLSPSEDPQRHCPSELLGTEAWRLLWPQPSAQNIPASMGNSKICQHCPFVGVFEGHLLHGHLFPFTSLDNVAVSSRRFSLFIQSPPASLSSLRTSPLSHPSSSLHCEGASGSSCLVAALGNTWSHCVNTRLILQYLDSERRQILIAKSPVAPLTSFVYTIKGEGLVLQAPGSSVTFGSVLSCTSLGLKELR", "length": 469 }, "evidence": [ { "id": "A0A8V0ZE34", "url": "https://omabrowser.org/oma/group/A0A8V0ZE34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15315-3", "protein_name": "DNA repair protein RAD51 homolog 2", "gene_name": "RAD51B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQILIAKSPLAPFTSFVYTIKEEGLVLQETTFCSVTQAELNWAPEILPPQPPEQLGLQMCHHTQLIF", "length": 384 }, "evidence": [ { "id": "A0A8V0ZE34", "url": "https://omabrowser.org/oma/group/A0A8V0ZE34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35719-1", "protein_name": "DNA repair protein RAD51 homolog 2", "gene_name": "Rad51b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSKKLRRVGLSPELCDRLSRYQIVNCQHFLSLSPLELMKVTGLSYRGVHELLHTVSKACAPQMQTAYELKTRRSAHLSPAFLSTTLCALDEALHGGVPCGSLTEITGPPGCGKTQFCIMMSVLATLPTSLGGLEGAVVYIDTESAFTAERLVEIAESRFPQYFNTEEKLLLTSSRVHLCRELTCEGLLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPKLQGNIKERNKFLGKGASLLKYLAGEFSIPVILTNQITTHLSGALPSQADLVSPADDLSLSEGTSGSSCLVAALGNTWGHCVNTRLILQYLDSERRQILIAKSPLAAFTSFVYTIKGEGLVLQGHERP", "length": 350 }, "evidence": [ { "id": "A0A8V0ZE34", "url": "https://omabrowser.org/oma/group/A0A8V0ZE34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "supramolecular fiber organization", "id": "GO:0097435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Rad51B-Rad51C-Rad51D-XRCC2 complex", "id": "GO:0033063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE34" }, { "id": "PS50162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 1", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 276, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBT9-1", "uniprot_ac": "A0A8V0ZBT9", "uniprot_id": "A0A8V0ZBT9_CHICK", "mass": { "chemical_mass": 110589.0, "monoisotopic_mass": 110589.0 }, "refseq": {}, "gene_names": [ { "name": "MDGA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ] } ], "protein_names": [ { "name": "MAM domain containing glycosylphosphatidylinositol anchor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MDGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9", "locus": { "chromosome": "3", "start_pos": 29754567, "end_pos": 29485324, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021262", "url": "https://www.ensembl.org/id/ENSGALG00010021262" } ] } } ], "crossref": [ { "id": "A0A8V0ZBT9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010145", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421431", "url": "https://www.ncbi.nlm.nih.gov/gene/421431", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSWQQAH", "url": "https://omabrowser.org/oma/group/NSWQQAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A2A3", "url": "https://www.orthodb.org/?gene=A0A3Q3A2A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZHH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZIX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIZ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q3A2A3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A2A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A2A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A2A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPPLRRHLASPRPERDGFTEPPDQLGVARTIVQPRGDIGLRRGWNSERNKFRRHLQTLEAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 987, "header": "tr|A0A8V0ZBT9-1|A0A8V0ZBT9_CHICK Isoform 1 of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3A2A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A3Q3A2A3-1", "sequence": { "sequence": "MLPGPLWLLFFAGDEGAALKMEMICVLFLSLVPAYSRGQGVYAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 969, "header": "tr|A0A3Q3A2A3-1|A0A8V0ZBT9_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29627218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051547.1", "url": "https://www.ensembl.org/id/ENSGALT00010051547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030738.1", "url": "https://www.ensembl.org/id/ENSGALP00010030738.1" } ] } }, { "isoform_ac": "A0A8V0ZBT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A8V0ZBT9-1", "sequence": { "sequence": "MRPPLRRHLASPRPERDGFTEPPDQLGVARTIVQPRGDIGLRRGWNSERNKFRRHLQTLEAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 987, "header": "tr|A0A8V0ZBT9-1|A0A8V0ZBT9_CHICK Isoform 1 of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29485352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051556.1", "url": "https://www.ensembl.org/id/ENSGALT00010051556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030747.1", "url": "https://www.ensembl.org/id/ENSGALP00010030747.1" } ] } }, { "isoform_ac": "A0A8V0ZHH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A8V0ZHH1-1", "sequence": { "sequence": "MASAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 930, "header": "tr|A0A8V0ZHH1-1|A0A8V0ZHH1_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29529432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051553.1", "url": "https://www.ensembl.org/id/ENSGALT00010051553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030744.1", "url": "https://www.ensembl.org/id/ENSGALP00010030744.1" } ] } }, { "isoform_ac": "A0A8V0ZIX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A8V0ZIX3-1", "sequence": { "sequence": "MRLMPEQQTSPAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 938, "header": "tr|A0A8V0ZIX3-1|A0A8V0ZIX3_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29574839, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051550.1", "url": "https://www.ensembl.org/id/ENSGALT00010051550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030741.1", "url": "https://www.ensembl.org/id/ENSGALP00010030741.1" } ] } }, { "isoform_ac": "A0A8V0ZIY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A8V0ZIY2-1", "sequence": { "sequence": "MYLIDQRGWSQDPPLPLRVGSGDKGILLAIPVYLQLSEAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTAPPALKLSVNETLVVNPGDNVTMQCSLTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 965, "header": "tr|A0A8V0ZIY2-1|A0A8V0ZIY2_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29638063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051544.1", "url": "https://www.ensembl.org/id/ENSGALT00010051544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030735.1", "url": "https://www.ensembl.org/id/ENSGALP00010030735.1" } ] } }, { "isoform_ac": "A0A8V0ZIZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9/entry#A0A8V0ZIZ4-1", "sequence": { "sequence": "MASAPAQAQIIHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVLNETLRIEKIQRLQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTISDVRGSFYQEKTVFLRCTVNSNPPARFIWKRGAETLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCSIPDKSITFQLTNTTGGDPQPEVLWSHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTAINNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYSWYKNGKPARFSDRLLITRNDPELPPVTCSLEIIDLRFSDYGTYLCVATFQGAPIPDLSVEVNISSETVPPTISVPKGQSTITVREGSRAELQCEVRGKPKPPIIWSRVDKETPMPSGTMTVETYDGKLRLESVSRDMSGTYKCQTARYNGFNIRPREALVQLNVQFPPVVEPAFQDVRQGMGRSVTLRCTMLKGSPMKVATSVWRFNGTLLAQPPAEQQDYSELKVDSVSRETSGSYECSISNDVGVSACLFQVSAKAYSPEFYYDTPNPTLSQKQSKNYSYILQWTQKEPDAVDPILKYRLEVRQLAQRNTIQTFIPVQKMEKGLLLEHILPNLKVPQSYEVRLTPITSFGAGDMAARIIRYMEPINYPSPTDNTCRFEDEKICGFVQDKMDNFDWTRQNALTQNPKRTVNTGPPTDISGTPEGYYMFIEASRPRVTGDKARLISPLYNITAKYYCVSFYYHMYGKHIGSLNLLVRVRNKRAIDTQVWSLSGNRGNMWQQAHVPINPPGPFQIIFEGVRGTSYEGDIAIDDVTLKKGDCPRKPIGPNKAVALPGSGVSAQHGPCLCGPLTFFLYVLLR", "length": 902, "header": "tr|A0A8V0ZIZ4-1|A0A8V0ZIZ4_CHICK Computationally mapped isoform of MAM domain containing glycosylphosphatidylinositol anchor 1 OS=Gallus gallus OX=9031 GN=MDGA1 PE=4 SV=1 CANONICAL=A0A8V0ZBT9-1" }, "locus": { "chromosome": "3", "start_pos": 29754259, "end_pos": 29529432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051554.1", "url": "https://www.ensembl.org/id/ENSGALT00010051554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030745.1", "url": "https://www.ensembl.org/id/ENSGALP00010030745.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MHX8-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "MDGA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIMHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYSCQVSVRNVCGIPDKAVSFQLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRQREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAVPVAAEAPDHSELRLDAVTRESSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNALVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPISSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRSKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPRQPLPQLWGPVATFLLALQR", "length": 955 }, "evidence": [ { "id": "A0A8V0ZBT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RVR8-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "MDGA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVTCLLLLALIPFHCRAQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAVTFRLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETSDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPGSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPAIPIAAEAPDHSELRLDAVTRDSSGSYECSVSNDVGSAVCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSVRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRKQMDPNKVVVMPGSGAPCQPRPQLWGSMAIFLLVWQR", "length": 955 }, "evidence": [ { "id": "A0A8V0ZBT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P85171-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "Mdga1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKSITFQLTNTTAPPTLKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGSPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRVERVSREMSGTYRCQTARYNGFNVRAREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAAEGPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGDMASRVIHYTEPINSPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMTIFLLALQR", "length": 956 }, "evidence": [ { "id": "A0A8V0ZBT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0PMG2-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "Mdga1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFQLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMASFPGSPVPDLSIEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRLESVSRDMSGTYRCQTARYNGFNVRPREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAVETPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYILTDLRVPHSYEIRLTPYTTFGAGDMASRIIHYTEPINLPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMAIFLLALQR", "length": 956 }, "evidence": [ { "id": "A0A8V0ZBT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NFP4-1", "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "MDGA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIREGDTLMLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPMLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDAVPQEKVTYQWFKNGKPARMSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRPREAQVQLNVQFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVVPAAAEAPDHAELRLDAVTRDSSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAVVKAIPVRRVEKGQLLEYILTDLRVPHSYEVRLTPYTTFGAGDMASRIIHYTEPINSPNLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTLKKGECPRKQTDPNKVVVMPGSGAPCQSSPQLWGPMAIFLLALQR", "length": 955 }, "evidence": [ { "id": "A0A8V0ZBT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "regulation of synaptic membrane adhesion", "id": "GO:0099179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" }, { "name": "regulation of presynapse assembly", "id": "GO:1905606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 675, "end_pos": 775, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 161, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT9" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 783, "end_pos": 950, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 615, "end_pos": 617 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 858, "end_pos": 860 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF72-1", "uniprot_ac": "A0A8V0ZF72", "uniprot_id": "A0A8V0ZF72_CHICK", "mass": { "chemical_mass": 86209.0, "monoisotopic_mass": 86209.0 }, "refseq": {}, "gene_names": [ { "name": "STAMBP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ] } ], "protein_names": [ { "name": "RNA/RNP complex-1-interacting phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#names_and_taxonomy" } ] }, { "name": "Dual specificity protein phosphatase 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#names_and_taxonomy" } ] }, { "name": "Phosphatase that interacts with RNA/RNP complex 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72#function" }, { "database": "UniProtKB", "id": "ARBA00054725", "url": "https://www.uniprot.org/uniprotkb/ARBA00054725#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STAMBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72", "locus": { "chromosome": "22", "start_pos": 3098465, "end_pos": 3080918, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020605", "url": "https://www.ensembl.org/id/ENSGALG00010020605" } ] } } ], "crossref": [ { "id": "A0A8V0ZF72", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000042555", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17665", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17665", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771090", "url": "https://www.ncbi.nlm.nih.gov/gene/771090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771090", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771090", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PXK6", "url": "https://www.orthodb.org/?gene=A0A1D5PXK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5M3", "url": "https://www.orthodb.org/?gene=A0A3Q2U5M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3ADY3", "url": "https://www.orthodb.org/?gene=A0A3Q3ADY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDT6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF72", "url": "https://www.orthodb.org/?gene=A0A8V0ZF72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PXK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5M3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADY3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGRGRSRVPERWTDYVPLGRRLPGTRFIAFKVPLRKSFNQNLHPEERFSPCDLIEKIKEQKEELGLIIDLTYTTRYYGPEELPATLRYSKILTMGHEIPNNQTIFQFKCVVKNFLRDNKDNDKLIGVHCTHGLNRTGYLVCRYLIDVEGMEPNTAIELFNRARGHPIERMNYIEDLRRRSGMKREVKNSGSVPLKGRVDAMLNCRKQKAEHRPQRSEHLLLTTSRNSGCAKKKKKRHHRAPEQLQEPLHKPGLAEKRWPCSLAPRNCPVSLPYNMQRNEVCFLAPGPLHQQPQEPHVARKRRRRRKKQLLSAAAGLMCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKYQETGFFKLTEHGLEEISSCRQKGFHPHSKDPPLFTTCNHVSVVERDVVLMDLR", "length": 748, "header": "tr|A0A8V0ZF72-1|A0A8V0ZF72_CHICK Isoform 1 of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=1 CANONICAL=A0A8V0ZF72-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#A0A1D5PXK6-1", "sequence": { "sequence": "MAGPRVVQRDDEKGRAVWELLSAAAGLMCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKYQETGFFKLTEHGLEEISSCRQKGFHPHSKDPPLFTTCNHVSVVERDVVLMDLR", "length": 458, "header": "tr|A0A1D5PXK6-1|A0A8V0ZF72_CHICK Computationally mapped isoform of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=2 CANONICAL=A0A8V0ZF72-1" }, "locus": { "chromosome": "22", "start_pos": 3097132, "end_pos": 3086522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049728.1", "url": "https://www.ensembl.org/id/ENSGALT00010049728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029382.1", "url": "https://www.ensembl.org/id/ENSGALP00010029382.1" } ] } }, { "isoform_ac": "A0A3Q2U5M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#A0A3Q2U5M3-1", "sequence": { "sequence": "MCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKYQETGFFKLTEHGLEEISSCRQKGFHPHSKDPPLFTTCNHVSVVERDVVLMDLR", "length": 431, "header": "tr|A0A3Q2U5M3-1|A0A8V0ZF72_CHICK Computationally mapped isoform of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=1 CANONICAL=A0A8V0ZF72-1" }, "locus": { "chromosome": "22", "start_pos": 3097132, "end_pos": 3086871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049733.1", "url": "https://www.ensembl.org/id/ENSGALT00010049733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029385.1", "url": "https://www.ensembl.org/id/ENSGALP00010029385.1" } ] } }, { "isoform_ac": "A0A3Q3ADY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#A0A3Q3ADY3-1", "sequence": { "sequence": "MCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHDRVFQTDRTRPGGDLFLSTERIPPPFQRPSPLHYLQSRVSSRERRGADGSTIGLLP", "length": 398, "header": "tr|A0A3Q3ADY3-1|A0A8V0ZF72_CHICK Computationally mapped isoform of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=1 CANONICAL=A0A8V0ZF72-1" }, "locus": { "chromosome": "22", "start_pos": 3097146, "end_pos": 3086871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049731.1", "url": "https://www.ensembl.org/id/ENSGALT00010049731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029384.1", "url": "https://www.ensembl.org/id/ENSGALP00010029384.1" } ] } }, { "isoform_ac": "A0A8V0ZDT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#A0A8V0ZDT6-1", "sequence": { "sequence": "MCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHSWSQVVLLEKFRSVGGSDPFLEHRPLWKWDAGLKADLGHPSLPSGAPAVSTWPLQ", "length": 397, "header": "tr|A0A8V0ZDT6-1|A0A8V0ZDT6_CHICK Computationally mapped isoform of STAM binding protein OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=1 CANONICAL=A0A8V0ZF72-1" }, "locus": { "chromosome": "22", "start_pos": 3095535, "end_pos": 3086871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049725.1", "url": "https://www.ensembl.org/id/ENSGALT00010049725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029381.1", "url": "https://www.ensembl.org/id/ENSGALP00010029381.1" } ] } }, { "isoform_ac": "A0A8V0ZF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72/entry#A0A8V0ZF72-1", "sequence": { "sequence": "MPGRGRSRVPERWTDYVPLGRRLPGTRFIAFKVPLRKSFNQNLHPEERFSPCDLIEKIKEQKEELGLIIDLTYTTRYYGPEELPATLRYSKILTMGHEIPNNQTIFQFKCVVKNFLRDNKDNDKLIGVHCTHGLNRTGYLVCRYLIDVEGMEPNTAIELFNRARGHPIERMNYIEDLRRRSGMKREVKNSGSVPLKGRVDAMLNCRKQKAEHRPQRSEHLLLTTSRNSGCAKKKKKRHHRAPEQLQEPLHKPGLAEKRWPCSLAPRNCPVSLPYNMQRNEVCFLAPGPLHQQPQEPHVARKRRRRRKKQLLSAAAGLMCLVMPKHADVSLPPEERVRSLIQMGSAVEVNEDVPPRRYYRSGVEILRMATIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKTAVIPEKKETMKKLKEVAFPRAEDLKKELLQRYTKDYTKYIEQKKEKEEEDARNLALQQQLEEERNRVALMKQQQAEQEQFLAFEEMIRRQELEKERLRIAQEFGKPEPSPESLDGPLIPGMEKPPTDLTPRVPLSPIHPASPSVGTVSSKPPVVDRSLKPSALGSTEHTAGMDALRQVIVPRELCHKFLQLADANTARGVETCGILCGKLMRNEFTITHVIVPKQYGGPDYCNTENEEELFLIQDQHGLVTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKYQETGFFKLTEHGLEEISSCRQKGFHPHSKDPPLFTTCNHVSVVERDVVLMDLR", "length": 748, "header": "tr|A0A8V0ZF72-1|A0A8V0ZF72_CHICK Isoform 1 of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=STAMBP PE=1 SV=1 CANONICAL=A0A8V0ZF72-1" }, "locus": { "chromosome": "22", "start_pos": 3097132, "end_pos": 3080943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049743.1", "url": "https://www.ensembl.org/id/ENSGALT00010049743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029392.1", "url": "https://www.ensembl.org/id/ENSGALP00010029392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771090", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771090", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" }, { "id": "PS50249", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MPN", "eco_id": "ECO_0000259", "start_pos": 581, "end_pos": 712, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 175, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZF72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF72" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 186, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 135, "end_pos": 137 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDQ4-1", "uniprot_ac": "A0A8V0ZDQ4", "uniprot_id": "A0A8V0ZDQ4_CHICK", "mass": { "chemical_mass": 37553.0, "monoisotopic_mass": 37553.0 }, "refseq": {}, "gene_names": [ { "name": "FRA10AC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4" } ] } ], "protein_names": [ { "name": "FRA10A associated CGG repeat 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FRA10AC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4", "locus": { "chromosome": "6", "start_pos": 21150690, "end_pos": 21124091, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020313", "url": "https://www.ensembl.org/id/ENSGALG00010020313" } ] } } ], "crossref": [ { "id": "A0A8V0ZDQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006622", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006622", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NWK6", "url": "https://www.orthodb.org/?gene=A0A1D5NWK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDQ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE47", "url": "https://www.orthodb.org/?gene=A0A8V0ZE47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11567", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11567", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11567:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11567:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NWK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NWK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGQGGYDSDFSDEENGEKSVQKTKSTKEDSLLVKPFQKPKQVKVAHRQFAAEEWDREEARKRRFHLISMDAYSRHRKLVNDYILYYGGKMEDFRRSGENDKTDLDVIRENHRFLWREDDEADMNWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRHEKEVISGKGQFSCGNKHCDGEEGLKSWEVNFGYVEHGEKRNALVKLRLCPECSYKLNFHHRRKEVKASKKRGTAVGNSKQPKIKKAKLSHSGKKKSKKKTHGDQVSSEDSDTSDKDSDNSDVQDGPSDADFWKGPLQEPDEKSREEEFDEYFQDLFL", "length": 319, "header": "tr|A0A8V0ZDQ4-1|A0A8V0ZDQ4_CHICK Isoform 1 of FRA10A associated CGG repeat 1 OS=Gallus gallus OX=9031 GN=FRA10AC1 PE=4 SV=1 CANONICAL=A0A8V0ZDQ4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NWK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4/entry#A0A1D5NWK6-1", "sequence": { "sequence": "MVPGQLRLAAAARGQGGYDSDFSDEENGEKSVQKTKSTKEDSLLVKPFQKPKQVKVAHRQFAAEEWDREEARKRRFHLISMDAYSRHRKLVNDYILYYGGKMEDFRRSGENDKTDLDVIRENHRFLWREDDEADMNWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRHEKEVISGKGQFSCGNKHCDGEEGLKSWEVNFGYVEHGEKRNALVKLRLCPECSYKLNFHHRRKEVKASKKRGTAVGNSKQPKIKKAKLSHSGKKKSKKKTHGGRNSPVKNIYCNKKLSESWAFY", "length": 296, "header": "tr|A0A1D5NWK6-1|A0A8V0ZDQ4_CHICK Computationally mapped isoform of FRA10A associated CGG repeat 1 OS=Gallus gallus OX=9031 GN=FRA10AC1 PE=4 SV=1 CANONICAL=A0A8V0ZDQ4-1" }, "locus": { "chromosome": "6", "start_pos": 21143743, "end_pos": 21124189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049029.1", "url": "https://www.ensembl.org/id/ENSGALT00010049029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028983.1", "url": "https://www.ensembl.org/id/ENSGALP00010028983.1" } ] } }, { "isoform_ac": "A0A8V0ZCQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4/entry#A0A8V0ZCQ8-1", "sequence": { "sequence": "MVPGQLRLAAAARGQGGYDSDFSDEENGEKSVQKTKSTKEDSLLVKPFQKPKQVKVAHRQFAAEEWDREEARKRRFHLISMDAYSRHRKLVNDYILYYGGKMEDFRRSGENDKTDLDVIRENHRFLWREDDEADMNWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRHEKEVISGKGQFSCGNKHCDGEEGLKSWEVNFGYVEHGEKRNALVKLRLCPECSYKLNFHHRRKEVKASKKRGTAVGNSKQPKIKKAKLSHSGKKKSKKKTHGDQVSSEDSDTSDKGKIQITVMYKMVLQMLIFGKALYKNQMKNHERKSSMNIFKTCFSET", "length": 333, "header": "tr|A0A8V0ZCQ8-1|A0A8V0ZCQ8_CHICK Computationally mapped isoform of FRA10A associated CGG repeat 1 OS=Gallus gallus OX=9031 GN=FRA10AC1 PE=4 SV=1 CANONICAL=A0A8V0ZDQ4-1" }, "locus": { "chromosome": "6", "start_pos": 21145959, "end_pos": 21124189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049036.1", "url": "https://www.ensembl.org/id/ENSGALT00010049036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028990.1", "url": "https://www.ensembl.org/id/ENSGALP00010028990.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4/entry#A0A8V0ZDQ4-1", "sequence": { "sequence": "MARGQGGYDSDFSDEENGEKSVQKTKSTKEDSLLVKPFQKPKQVKVAHRQFAAEEWDREEARKRRFHLISMDAYSRHRKLVNDYILYYGGKMEDFRRSGENDKTDLDVIRENHRFLWREDDEADMNWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRHEKEVISGKGQFSCGNKHCDGEEGLKSWEVNFGYVEHGEKRNALVKLRLCPECSYKLNFHHRRKEVKASKKRGTAVGNSKQPKIKKAKLSHSGKKKSKKKTHGDQVSSEDSDTSDKDSDNSDVQDGPSDADFWKGPLQEPDEKSREEEFDEYFQDLFL", "length": 319, "header": "tr|A0A8V0ZDQ4-1|A0A8V0ZDQ4_CHICK Isoform 1 of FRA10A associated CGG repeat 1 OS=Gallus gallus OX=9031 GN=FRA10AC1 PE=4 SV=1 CANONICAL=A0A8V0ZDQ4-1" }, "locus": { "chromosome": "6", "start_pos": 21145952, "end_pos": 21127526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049026.1", "url": "https://www.ensembl.org/id/ENSGALT00010049026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028982.1", "url": "https://www.ensembl.org/id/ENSGALP00010028982.1" } ] } }, { "isoform_ac": "A0A8V0ZE47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4/entry#A0A8V0ZE47-1", "sequence": { "sequence": "MILILVTRRMERSLCKRLKVLPVRGWQGTRSRKGTQSGQLAPADQRDVQYHMAPCSVSKAGEKRRKGGYSAICTKEDSLLVKPFQKPKQVKVAHRQFAAEEWDREEARKRRFHLISMDAYSRHRKLVNDYILYYGGKMEDFRRSGENDKTDLDVIRENHRFLWREDDEADMNWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRHEKEVISGKGQFSCGNKHCDGEEGLKSWEVNFGYVEHGEKRNALVKLRLCPECSYKLNFHHRRKEVKASKKRGTAVGNSKQPKIKKAKLSHSGKKKSKKKTHGDQVSSEDSDTSDKDSDNSDVQDGPSDADFWKGPLQEPDEKSREEEFDEYFQDLFL", "length": 365, "header": "tr|A0A8V0ZE47-1|A0A8V0ZE47_CHICK Computationally mapped isoform of FRA10A associated CGG repeat 1 OS=Gallus gallus OX=9031 GN=FRA10AC1 PE=4 SV=1 CANONICAL=A0A8V0ZDQ4-1" }, "locus": { "chromosome": "6", "start_pos": 21145952, "end_pos": 21128237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049032.1", "url": "https://www.ensembl.org/id/ENSGALT00010049032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028986.1", "url": "https://www.ensembl.org/id/ENSGALP00010028986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEN9-1", "uniprot_ac": "A0A8V0ZEN9", "uniprot_id": "A0A8V0ZEN9_CHICK", "mass": { "chemical_mass": 24864.0, "monoisotopic_mass": 24864.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC20", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat protein SHOC-2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9", "locus": { "chromosome": "6", "start_pos": 12234016, "end_pos": 12237090, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020546", "url": "https://www.ensembl.org/id/ENSGALG00010020546" } ] } } ], "crossref": [ { "id": "A0A8V0ZEN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030964", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769461", "url": "https://www.ncbi.nlm.nih.gov/gene/769461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769461", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WINVKSN", "url": "https://omabrowser.org/oma/group/WINVKSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P009", "url": "https://www.orthodb.org/?gene=A0A1D5P009", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEN9", "url": "https://www.orthodb.org/?gene=A0A8V0ZEN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P009", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P009", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P009-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P009-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRRMGEAVARVARRVNETVESQGDTLDLADCKLVAFPAGIYKAVRSVTQGIHRISLANNELKALGARFATTFSQLRELNLEGNLLHRLPQELGSLLHLRTINLARNKFRHFPEPLVAAPALESINLEGNEIAGQGGGAAGSRVQAARCQQRHWPTCPRCGASTCVPTLCALLYACSSGPWSPSSCYCHLRAMSPRPDMSLLPGAWRSAPWPRSSPRLPAAGTMCPMPD", "length": 229, "header": "tr|A0A8V0ZEN9-1|A0A8V0ZEN9_CHICK Isoform 1 of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=LRRC20 PE=4 SV=1 CANONICAL=A0A8V0ZEN9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P009-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9/entry#A0A1D5P009-1", "sequence": { "sequence": "MQRRMGEAVARVARRVNETVESQGDTLDLADCKLVAFPAGIYKAVRSVTQGIHRISLANNELKALGARFATTFSQLRELNLEGNLLHRLPQELGSLLHLRTINLARNKFRHFPEPLVAAPALESINLEGNEIAEVPTEALANMSSLRSLNLRANPVCPAVRLLVRPLVPFELLLSPEGNVPTA", "length": 183, "header": "tr|A0A1D5P009-1|A0A8V0ZEN9_CHICK Computationally mapped isoform of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=LRRC20 PE=4 SV=1 CANONICAL=A0A8V0ZEN9-1" }, "locus": { "chromosome": "6", "start_pos": 12236789, "end_pos": 12234306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049613.1", "url": "https://www.ensembl.org/id/ENSGALT00010049613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029311.1", "url": "https://www.ensembl.org/id/ENSGALP00010029311.1" } ] } }, { "isoform_ac": "A0A8V0ZEN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN9/entry#A0A8V0ZEN9-1", "sequence": { "sequence": "MQRRMGEAVARVARRVNETVESQGDTLDLADCKLVAFPAGIYKAVRSVTQGIHRISLANNELKALGARFATTFSQLRELNLEGNLLHRLPQELGSLLHLRTINLARNKFRHFPEPLVAAPALESINLEGNEIAGQGGGAAGSRVQAARCQQRHWPTCPRCGASTCVPTLCALLYACSSGPWSPSSCYCHLRAMSPRPDMSLLPGAWRSAPWPRSSPRLPAAGTMCPMPD", "length": 229, "header": "tr|A0A8V0ZEN9-1|A0A8V0ZEN9_CHICK Isoform 1 of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=LRRC20 PE=4 SV=1 CANONICAL=A0A8V0ZEN9-1" }, "locus": { "chromosome": "6", "start_pos": 12236789, "end_pos": 12234209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049616.1", "url": "https://www.ensembl.org/id/ENSGALT00010049616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029313.1", "url": "https://www.ensembl.org/id/ENSGALP00010029313.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A8F2-1", "protein_name": "Leucine rich repeat containing 20", "gene_name": "LRRC20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRKMGEAVARVARKVNETVESGSDTLDLAECKLVSFPIGIYKVLRNVTDQIHLITLANNELKSLTSKFMTTFSQLRELHLEGNFLHRLPNEVSTLQHLKAIDLSRNHFHDFPEQLTTLPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGARAPPP", "length": 184 }, "evidence": [ { "id": "A0A8V0ZEN9", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MBS6-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "Lrrc20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRKMGEAVARVARRVNETVESGSDTLDLADCKLVSFPICIYKVLRNVSDQILLITLANNELKSLTSKFMTTFSQLRELHLEGNYLHRLPNEVSSLQHLKAIDLSRNQFRDFPEQLTTLPELETINLEENEIVDVPVEKLATMPALRVINLRLNPLSAEVRVIAPPLIKFDMLMSPEDAQAPPP", "length": 184 }, "evidence": [ { "id": "A0A8V0ZEN9", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LUD9-1", "protein_name": "Leucine rich repeat containing 20", "gene_name": "Lrrc20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRKMGEAVARVARKVNETVESSSDTLDLADCKLVSFPICIYKVLRNVSDQIHLITLANNELKSLTSKFMTTFSQLRELRLEGNYLYRLPNEVSSLQHLRAIDLSRNQFQDFPEQLTTLPALETINLEENEIVDVPVEKLAAMPALRTINLRLNPLSAEVRVIAPPLIKFDMLMTPEDTRAPLP", "length": 184 }, "evidence": [ { "id": "A0A8V0ZEN9", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CI70-1", "protein_name": "Leucine-rich repeat-containing protein 20", "gene_name": "Lrrc20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRKMGEAVARVARKVNETVESGSDTLDLADCKLVSFPICIYKVLRNVSDQIHLITLANNELKSLTSKFMTTFNQLRELRLEGNYLFRLPNEVSSLQHLRAIDLSRNQFQDFPEQLTTLPALETINLEENEIVDVPVEKLAAMPALRVINLRLNPLSADVRVIAPPLIKFDMLMSPEDTRAPPP", "length": 184 }, "evidence": [ { "id": "A0A8V0ZEN9", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCA0-1", "protein_name": "Leucine-rich repeat-containing protein 20", "gene_name": "LRRC20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKKMGEAVARVARKVNETVESGSDTLDLAECKLVSFPIGIYKVLRNVSGQIHLITLANNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVEKLAAMPALRSINLRFNPLNAEVRVIAPPLIKFDMLMSPEGARAPLP", "length": 184 }, "evidence": [ { "id": "A0A8V0ZEN9", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF81-1", "uniprot_ac": "A0A8V0ZF81", "uniprot_id": "A0A8V0ZF81_CHICK", "mass": { "chemical_mass": 101184.0, "monoisotopic_mass": 101184.0 }, "refseq": {}, "gene_names": [ { "name": "VPS39", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ] } ], "protein_names": [ { "name": "VPS39 subunit of HOPS complex", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VPS39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81", "locus": { "chromosome": "5", "start_pos": 25099972, "end_pos": 25123107, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020603", "url": "https://www.ensembl.org/id/ENSGALG00010020603" } ] } } ], "crossref": [ { "id": "A0A8V0ZF81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008991", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008991", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423230", "url": "https://www.ncbi.nlm.nih.gov/gene/423230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EEYCNQV", "url": "https://omabrowser.org/oma/group/EEYCNQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P704", "url": "https://www.orthodb.org/?gene=A0A1D5P704", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z827", "url": "https://www.orthodb.org/?gene=A0A8V0Z827", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEY6", "url": "https://www.orthodb.org/?gene=A0A8V0ZEY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF81", "url": "https://www.orthodb.org/?gene=A0A8V0ZF81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P704", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P704-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P704-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z827", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z827", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z827-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z827-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHDAFEHVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIKKDIGCNRFEVTLEKSNKNFSKKIQQNSFFQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHSDNGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPVADGKVAVGQDDLTVVLNEEGVCTQKCALNWTDIPIAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGTNIIYVASNHFVWRLIPVSIATQIQQLLQDKQFELALQLAEMKDDSDSEKRQQIHHIKNLFAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPGLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGAENLHLVFSYSVWVLRDFPEDGLKIFTEDLPEVEALPRDKVLSFLIENFKSLAIPYLEHIIHVWEETGAHFHNCLIQLYCEKVQGLMKEYLNSFPADKSPVPAGEEGGDLGDYRKKLLLFLEKSSCYEPSRLISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTNMAENYCHKHYDRNKDGNKDVYLSLLRMYLSPPSVHCLGPIKMEVLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQISEIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCTVCKKKIGNSAFARYPNAIVVHYFCSKEVNTLDT", "length": 880, "header": "tr|A0A8V0ZF81-1|A0A8V0ZF81_CHICK Isoform 1 of VPS39 subunit of HOPS complex OS=Gallus gallus OX=9031 GN=VPS39 PE=1 SV=1 CANONICAL=A0A8V0ZF81-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P704-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81/entry#A0A1D5P704-1", "sequence": { "sequence": "MHDAFEHVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIKKDIVPGEVMSSESVCCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHSDNGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPVADGKVAVGQDDLTVVLNEEGVCTQKCALNWTDIPIAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGTNIIYVASNHFVWRLIPVSIATQIQQLLQDKQFELALQLAEMKDDSDSEKRQQIHHIKNLFAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPGLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGAENLHLVFSYSVWVLRDFPEDGLKIFTEDLPEVEALPRDKVLSFLIENFKSLAIPYLEHIIHVWEETGAHFHNCLIQLYCEKVQGLMKEYLNSFPADKSPVPAGEEGGDLGDYRKKLLLFLEKSSCYEPSRLISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTNMAENYCHKHYDRNKDGNKDVYLSLLRMYLSPPSVHCLGPIKMEVLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQISEIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCTVCKKKIGNSAFARYPNAIVVHYFCSKEVNTLDT", "length": 886, "header": "tr|A0A1D5P704-1|A0A8V0ZF81_CHICK Computationally mapped isoform of VPS39 subunit of HOPS complex OS=Gallus gallus OX=9031 GN=VPS39 PE=1 SV=2 CANONICAL=A0A8V0ZF81-1" }, "locus": { "chromosome": "5", "start_pos": 25122965, "end_pos": 25102084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049758.1", "url": "https://www.ensembl.org/id/ENSGALT00010049758.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029402.1", "url": "https://www.ensembl.org/id/ENSGALP00010029402.1" } ] } }, { "isoform_ac": "A0A8V0Z827-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81/entry#A0A8V0Z827-1", "sequence": { "sequence": "MHDAFEHVPILEKLPLQIDCLAAWGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHSDNGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPVADGKVAVGQDDLTVVLNEEGVCTQKCALNWTDIPIAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGTNIIYVASNHFVWRLIPVSIATQIQQLLQDKQFELALQLAEMKDDSDSEKRQQIHHIKNLFAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPGLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGAENLHLVFSYSVWVLRDFPEDGLKIFTEDLPEVEALPRDKVLSFLIENFKSLAIPYLEHIIHVWEETGAHFHNCLIQLYCEKVQGLMKEYLNSFPADKSPVPAGEEGGDLGDYRKKLLLFLEKSSCYEPSRLISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTNMAENYCHKHYDRNKDGNKDVYLSLLRMYLSPPSVHCLGPIKMEVLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQISEIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCTVCKKKIGNSAFARYPNAIVVHYFCSKEVNTLDT", "length": 853, "header": "tr|A0A8V0Z827-1|A0A8V0ZF81_CHICK Computationally mapped isoform of VPS39 subunit of HOPS complex OS=Gallus gallus OX=9031 GN=VPS39 PE=1 SV=1 CANONICAL=A0A8V0ZF81-1" }, "locus": { "chromosome": "5", "start_pos": 25122965, "end_pos": 25102084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049749.1", "url": "https://www.ensembl.org/id/ENSGALT00010049749.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029394.1", "url": "https://www.ensembl.org/id/ENSGALP00010029394.1" } ] } }, { "isoform_ac": "A0A8V0ZEY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81/entry#A0A8V0ZEY6-1", "sequence": { "sequence": "MHDAFEHVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIKKDIGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLVPALPTPACVDFSCLRPQNNIYVHDLLTFQQITTVSKAKGASLFTCDLQHSDNGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPVADGKVAVGQDDLTVVLNEEGVCTQKCALNWTDIPIAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGTNIIYVASNHFVWRLIPVSIATQIQQLLQDKQFELALQLAEMKDDSDSEKRQQIHHIKNLFAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPGLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGAENLHLVFSYSVWVLRDFPEDGLKIFTEDLPEVEALPRDKVLSFLIENFKSLAIPYLEHIIHVWEETGAHFHNCLIQLYCEKVQGLMKEYLNSFPADKSPVPAGEEGGDLGDYRKKLLLFLEKSSCYEPSRLISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTNMAENYCHKHYDRNKDGNKDVYLSLLRMYLSPPSVHCLGPIKMEVLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQISEIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCTVCKKKIGNSAFARYPNAIVVHYFCSKEVNTLDT", "length": 892, "header": "tr|A0A8V0ZEY6-1|A0A8V0ZEY6_CHICK Computationally mapped isoform of VPS39 subunit of HOPS complex OS=Gallus gallus OX=9031 GN=VPS39 PE=1 SV=1 CANONICAL=A0A8V0ZF81-1" }, "locus": { "chromosome": "5", "start_pos": 25122965, "end_pos": 25102084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049736.1", "url": "https://www.ensembl.org/id/ENSGALT00010049736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029388.1", "url": "https://www.ensembl.org/id/ENSGALP00010029388.1" } ] } }, { "isoform_ac": "A0A8V0ZF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81/entry#A0A8V0ZF81-1", "sequence": { "sequence": "MHDAFEHVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIKKDIGCNRFEVTLEKSNKNFSKKIQQNSFFQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHSDNGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPVADGKVAVGQDDLTVVLNEEGVCTQKCALNWTDIPIAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGTNIIYVASNHFVWRLIPVSIATQIQQLLQDKQFELALQLAEMKDDSDSEKRQQIHHIKNLFAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPGLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGAENLHLVFSYSVWVLRDFPEDGLKIFTEDLPEVEALPRDKVLSFLIENFKSLAIPYLEHIIHVWEETGAHFHNCLIQLYCEKVQGLMKEYLNSFPADKSPVPAGEEGGDLGDYRKKLLLFLEKSSCYEPSRLISDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTNMAENYCHKHYDRNKDGNKDVYLSLLRMYLSPPSVHCLGPIKMEVLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQISEIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCTVCKKKIGNSAFARYPNAIVVHYFCSKEVNTLDT", "length": 880, "header": "tr|A0A8V0ZF81-1|A0A8V0ZF81_CHICK Isoform 1 of VPS39 subunit of HOPS complex OS=Gallus gallus OX=9031 GN=VPS39 PE=1 SV=1 CANONICAL=A0A8V0ZF81-1" }, "locus": { "chromosome": "5", "start_pos": 25122965, "end_pos": 25102084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049761.1", "url": "https://www.ensembl.org/id/ENSGALT00010049761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029403.1", "url": "https://www.ensembl.org/id/ENSGALP00010029403.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B0G127-1", "protein_name": "Tetratricopeptide-like helical domain-containing protein", "gene_name": "vps39", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKVDMNAFVSQNLFDKFPQRIECIEQWEYKGKKHLFIGTTEGHVLVYDVIEKENQHGNIQVSVIIRDTKLVSKKPITQMSIFDDYNKLLVLTDGDLKVYDLIQFDVTTGITLMKAKGCSTYAVSYQPGSLSLVAAVKKKLVLYGWDGSDFYELKEFNMPDIAKHIDYRGNFIIVCFKKVYNIINTQDGSVINVDADKLTFTTFLQENEFLMVKGSMSFFINTAGNPVRRHSITWQDAPSSMSIYQPFAISIEPRLVEVQILPDPNDPKTISQSLFLPACKSISAKRDIYVSSATSIWRLQPLPILDLVDQMVTKQEYETAINLLQTSKDIIPGIKERLIKIKTSAAYHLFSKEQFQAAMGYFISAQVDPLKIISLYPGLLPAHLQDKLSTPFNIRDIENNPRALPELEHYLVEFRKNKIEYSSPPELLNSGYTLQELVDTTLLKVYIKHKASLIPHFFHLKNHCHIEESERVLLEEKKLTELILFYKSKDLHRKALTLLAKSSNISPNDTISYLSQLGEKHIGIILEHSKWVLQKCPEDALKIFTVDRKDPLSPDDVIPHLKQCAPSLLRPYLEHIINDPISPNKNPEYHNQLVFEYLGSILELIKQTPNSAIVREPGLIPAGKESGELGELRTKIIQFLENSKYYLPEKMLSRFPSNDLYEERAILLSKIGRHEQALAIYAHKLKNFAMAEEYCDRHYNKDSEESRDVYLSLLNVYLKPTDANTSPLLDPALKLLNKHYRSINTPKALSLLPLNTPIDQLYPFFESVIRDNTKTKRDNQIVKNLFKSENFKIKDELSQLKTGVIKITEDLTCPICNKIFLGTQAFVARPDGTALHYHHKNDKQHQSWFE", "length": 851 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "E9PT04-1", "protein_name": "VPS39 subunit of HOPS complex", "gene_name": "Vps39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLLSRCRSWRSFHCRLTAWLPGEWLLVGTKQGHLLLYRIRKDVGCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHTETGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDAKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIVAVLPRYVEIRTLEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPTLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKQKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSIWVLRDFPEDGLKIFTEDLPEVESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGTRFHNCLIQLYCEKVQNLMKDYLLSLPTGKSPVPAGEEAGELGESRQKLLTFLEISSSYDPGRLICDFPFDGLLEERALLLGRMGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNSADT", "length": 873 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SFK5-1", "protein_name": "VPS39 subunit of HOPS complex", "gene_name": "VPS39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVSADVASPESGSCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHTETGDEVLRMCVAVKKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPVLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRDRVLGFLIENFKSLAIPYLEHVIHVWEETGSRFHNCLIQLYCEKVQGLMKEYLLSFPAGTAPVPAGEEEGELGEYRRKLLLFLEISGYYDPARLICDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTRMAEEYCHKHYDQNKDGNKDVYLSLLRMYLSPPSVHCLGPIKLELLEPQANLQAALQVLELHHSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT", "length": 886 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8L5Y0-1", "protein_name": "Vacuolar sorting protein 39", "gene_name": "VPS39", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVHNAYDSFQLLKDCPARIDAVESYGSKLFAGCYDGSLRIYSPPESSASDPSELHQETYVLEKTVAGFSKKPIVAMEVLASRELLLSLSESIAFHGLPNLETVAVITKAKGANAYSWDDRRGFLCFSRQKRVCVFKHDGGGGFVEVRDYGVPDTVKSISWCGENICLGIKKEYVILNTANGTLSEVFPSGRVAPPLVISLPSGELILGKENIGVFVDQNGKLLQTERICWSEAPTSIVIQNPYAIALLPRRVEVRLLRSPYPLIQTIVLQNIRRLVKSNNAVIVGLDNSVYVLFPVSIGAQIVQLTASGNFEEALALCKVLPPDESSLRAAKESSIHTRFAHYLFENGSYEEAMEHFLASQVDITHVLSMYPSIILPKTTIIPQPDKMVDISGDEASLSRGSSGISDDMESSSPRYFLESEDNADLESKKMSHNTLMALIKYLLKRRPAVIEKATSEGTEEVISDAVGKTYGANDSSKSKKSSKGRGMIPLNSGAREMAAILDTALLQALLHTGQSGAAIELLKGVNYSDVKICEEILMKSKNYSALLELFKSNSMHHEALKLLNQLADESKTNQSQTDVTQIFSPELIIEYLKPLCRTDPMLVLEYSMLVLESCPTQTIDLFLSGNISADLVNSYLKQHAPNMQGRYLELMMAMNDTAVSGNLQNEMVQIYLSEVLDLYAAKSAQQKWDEKDHPPERKKLLSALESISGYSPQPLLKRLPRDALYEERAVILGKMNQHELALSIYVHKLHAPDLALAYCDRIYESVTYLPSGKPSSNIYLTVLQIYLNPKKSAKDFAKRIVALGSFESSDTTKMMDSVLSSKAKGGRSKKIVAIEGAEDMRVGLSSSTDSGRSDVDTEEPLEEGDSTVMISEVLDLLSQRWERINGAQALKLLPRETKLHNLLPFLAPLLRNSSEAHRNFSVIKSLRQSENLQVKEELYKHRKGVAQVTSESMCSLCNKKIGTSVFAVYPNGKTLVHFVCFRDSQGMKAVSKTTHGRRR", "length": 1000 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8R5L3-1", "protein_name": "Vam6/Vps39-like protein", "gene_name": "Vps39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVPADVASPESGSCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHTETGEEVLRMCVAVRKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIVAVLPRYVEIRTLEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPTLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGSQFHNCLIQLYCEKVQSLMKDYLLSLPTGKSPVPAGEEGGELGEYRQKLLMFLEISSHYDPGRLICDFPFDGLLEERALLLGRMGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNSADT", "length": 886 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JC1-1", "protein_name": "Vam6/Vps39-like protein", "gene_name": "VPS39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVPADVASPESGSCNRFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLFTCDLQHTETGEEVLRMCVAVKKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVGFKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPVLSGAELEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRDRVLGFLIENFKGLAIPYLEHIIHVWEETGSRFHNCLIQLYCEKVQGLMKEYLLSFPAGKTPVPAGEEEGELGEYRQKLLMFLEISSYYDPGRLICDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTRMAEEYCHKHYDRNKDGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPKANLQAALQVLELHHSKLDTTKALNLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT", "length": 886 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEA2-1", "protein_name": "Vacuolar protein sorting-associated protein 39 homolog", "gene_name": "Vps39", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHQAYSVHSILKQGVQIESIAAYGNHVILGTRSGQLIMYSVDEETGVDMRMFNKNFSRKPITQMEVIASENLLFVLTDLQVQVCDIRRIESNFAFMHSAPDTKGCTLFTMDVDTPKSTTGRVATVIRVCCAIRRRLVFFFWKEDKLNSLELIIELSDVPRTLCWVGHAVCVGFKDEYVVYDISGKAPKKHNLFLTSSSISRDPCICLIRNNMLGISKDSYLVVVDPSQYKESDGINNSTDVRPAAMDSNSSLTPLLWSSPLLDLVWDEPFAVGRVNNAIEVRSLVGKDTLVQTIPELQKTKFLVHADKGTIFAAATSELWCIRMVEIPIQRQQLLQQKKFQLAIELTQISDEPAADRAQTIRQIHMLYAKELFTNKEFSAAMKEFEKAAIDPYDVIRLFPNLVPEPKPGTEDVTVPTSSTPALEDSDLENAYLALIEYLAWARQREVVKLRDTKSSSKSLLEIIDTTLLKCYLQTNDSLVAPLLRLNQCHLEESEKTLKKHNKISELIILYQMKGKHKEALKLLREQASIEGSVLQGRKRTIRYLQELGGDHLPLIFEFADWVLNDNPEEGLTIFTDELIEVESLPRAKVLDFFISKHKALVIPYLEHVITEWKDGNTLLHNVLLKQYREKVQRLLAQQEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEEFPTNILLEERALILGRLKKHDNVLSIYIHVLGDVAKATAYAEAHYKEDKHIFHTLIKCILIPPTQPLYDGVPLHPDFSQVNREVALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKSIRKMMADKHEMQMMCGFLEAESTRLENALEEQRNISFELNESSVCSECKKRFQTQSAFVRYPNGHIVHLSCHDRLARAAAQQ", "length": 876 }, "evidence": [ { "id": "A0A8V0ZF81", "url": "https://omabrowser.org/oma/group/A0A8V0ZF81/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "vacuole fusion", "id": "GO:0097576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "AP-3 adaptor complex", "id": "GO:0030123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "lysosomal HOPS complex", "id": "GO:1902501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF81" }, { "id": "PS50219", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNH", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 288, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_ac": "A0A8V0ZE07", "uniprot_id": "A0A8V0ZE07_CHICK", "mass": { "chemical_mass": 17630.0, "monoisotopic_mass": 17630.0 }, "refseq": {}, "gene_names": [ { "name": "LIMO1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ] } ], "protein_names": [ { "name": "LIM domain only 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LIMO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZE07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE07", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000035679", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000035679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09388", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09388", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858792", "url": "https://www.ncbi.nlm.nih.gov/gene/100858792", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858792", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858792", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PI54", "url": "https://www.orthodb.org/?gene=A0A1D5PI54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UEP6", "url": "https://www.orthodb.org/?gene=A0A3Q2UEP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE07", "url": "https://www.orthodb.org/?gene=A0A8V0ZE07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF57", "url": "https://www.orthodb.org/?gene=A0A8V0ZF57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF64", "url": "https://www.orthodb.org/?gene=A0A8V0ZF64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45787", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45787", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45787:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45787:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8939236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PI54", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PI54-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UEP6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UEP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UEP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UEP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158, "header": "tr|A0A8V0ZE07-1|A0A8V0ZE07_CHICK Isoform 1 of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=1 CANONICAL=A0A8V0ZE07-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PI54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#A0A1D5PI54-1", "sequence": { "sequence": "MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFESQVQ", "length": 145, "header": "tr|A0A1D5PI54-1|A0A8V0ZE07_CHICK Computationally mapped isoform of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=2 CANONICAL=A0A8V0ZE07-1" }, "locus": { "chromosome": "5", "start_pos": 9812956, "end_pos": 9801617, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049865.1", "url": "https://www.ensembl.org/id/ENSGALT00010049865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029457.1", "url": "https://www.ensembl.org/id/ENSGALP00010029457.1" } ] } }, { "isoform_ac": "A0A3Q2UEP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#A0A3Q2UEP6-1", "sequence": { "sequence": "MMVLEQDDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFESQVQ", "length": 156, "header": "tr|A0A3Q2UEP6-1|A0A8V0ZE07_CHICK Computationally mapped isoform of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=1 CANONICAL=A0A8V0ZE07-1" }, "locus": { "chromosome": "5", "start_pos": 9812956, "end_pos": 9769852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049853.1", "url": "https://www.ensembl.org/id/ENSGALT00010049853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029450.1", "url": "https://www.ensembl.org/id/ENSGALP00010029450.1" } ] } }, { "isoform_ac": "A0A8V0ZE07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#A0A8V0ZE07-1", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158, "header": "tr|A0A8V0ZE07-1|A0A8V0ZE07_CHICK Isoform 1 of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=1 CANONICAL=A0A8V0ZE07-1" }, "locus": { "chromosome": "5", "start_pos": 9811678, "end_pos": 9765941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049860.1", "url": "https://www.ensembl.org/id/ENSGALT00010049860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029454.1", "url": "https://www.ensembl.org/id/ENSGALP00010029454.1" } ] } }, { "isoform_ac": "A0A8V0ZF57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#A0A8V0ZF57-1", "sequence": { "sequence": "MASLTGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFESQVQ", "length": 153, "header": "tr|A0A8V0ZF57-1|A0A8V0ZF57_CHICK Computationally mapped isoform of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=1 CANONICAL=A0A8V0ZE07-1" }, "locus": { "chromosome": "5", "start_pos": 9812956, "end_pos": 9769123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049855.1", "url": "https://www.ensembl.org/id/ENSGALT00010049855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029451.1", "url": "https://www.ensembl.org/id/ENSGALP00010029451.1" } ] } }, { "isoform_ac": "A0A8V0ZF64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07/entry#A0A8V0ZF64-1", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFESQVQ", "length": 155, "header": "tr|A0A8V0ZF64-1|A0A8V0ZF64_CHICK Computationally mapped isoform of LIM domain only 1 OS=Gallus gallus OX=9031 GN=LIMO1 PE=4 SV=1 CANONICAL=A0A8V0ZE07-1" }, "locus": { "chromosome": "5", "start_pos": 9812956, "end_pos": 9765941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049864.1", "url": "https://www.ensembl.org/id/ENSGALT00010049864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029456.1", "url": "https://www.ensembl.org/id/ENSGALP00010029456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858792", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858792", "resource": "KEGG Pathway" }, { "id": "R-GGA-8939236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of HSCs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A8V0ZE07", "url": "https://omabrowser.org/oma/group/A0A8V0ZE07/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE07" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 83, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"chemical_mass": 118262.0, "monoisotopic_mass": 118262.0 }, "refseq": {}, "gene_names": [ { "name": "GRIP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" } ] } ], "protein_names": [ { "name": "Glutamate receptor interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82", "locus": { "chromosome": "12", "start_pos": 11199980, "end_pos": 11423564, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021367", "url": "https://www.ensembl.org/id/ENSGALG00010021367" } ] } } ], "crossref": [ { "id": "A0A8V0ZC82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037545", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06681", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06681", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06682", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06682", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06687", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06687", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416043", "url": "https://www.ncbi.nlm.nih.gov/gene/416043", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETKTHDY", "url": "https://omabrowser.org/oma/group/ETKTHDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSV7", "url": "https://www.orthodb.org/?gene=A0A1D5PSV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC77", "url": "https://www.orthodb.org/?gene=A0A8V0ZC77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC82", "url": "https://www.orthodb.org/?gene=A0A8V0ZC82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC89", "url": "https://www.orthodb.org/?gene=A0A8V0ZC89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46227:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46227:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416993", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PSV7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNVHLQAEHGDASCLRNDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1086, "header": "tr|A0A8V0ZC82-1|A0A8V0ZC82_CHICK Isoform 1 of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PSV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A1D5PSV7-1", "sequence": { "sequence": "MLCGLKKDLQSDFDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1081, "header": "tr|A0A1D5PSV7-1|A0A8V0ZC82_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=2 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11265833, "end_pos": 11200984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051766.1", "url": "https://www.ensembl.org/id/ENSGALT00010051766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030880.1", "url": "https://www.ensembl.org/id/ENSGALP00010030880.1" } ] } }, { "isoform_ac": "A0A8V0ZC77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A8V0ZC77-1", "sequence": { "sequence": "MLLPPLGLRKKSMHFLQTFLRWRALRDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVINAKCSSGGWDGVNEWLRGREK", "length": 1055, "header": "tr|A0A8V0ZC77-1|A0A8V0ZC77_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11286934, "end_pos": 11203614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051772.1", "url": "https://www.ensembl.org/id/ENSGALT00010051772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030882.1", "url": "https://www.ensembl.org/id/ENSGALP00010030882.1" } ] } }, { "isoform_ac": "A0A8V0ZC82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A8V0ZC82-1", "sequence": { "sequence": "MLNVHLQAEHGDASCLRNDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1086, "header": "tr|A0A8V0ZC82-1|A0A8V0ZC82_CHICK Isoform 1 of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11382094, "end_pos": 11200984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051779.1", "url": "https://www.ensembl.org/id/ENSGALT00010051779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030887.1", "url": "https://www.ensembl.org/id/ENSGALP00010030887.1" } ] } }, { "isoform_ac": "A0A8V0ZC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A8V0ZC89-1", "sequence": { "sequence": "MQDGDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1072, "header": "tr|A0A8V0ZC89-1|A0A8V0ZC89_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11423525, "end_pos": 11200984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051787.1", "url": "https://www.ensembl.org/id/ENSGALT00010051787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030892.1", "url": "https://www.ensembl.org/id/ENSGALP00010030892.1" } ] } }, { "isoform_ac": "A0A8V0ZHU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A8V0ZHU8-1", "sequence": { "sequence": "MFAVSLKCRLGVVRRRNKDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1086, "header": "tr|A0A8V0ZHU8-1|A0A8V0ZHU8_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11299478, "end_pos": 11200984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051775.1", "url": "https://www.ensembl.org/id/ENSGALT00010051775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030884.1", "url": "https://www.ensembl.org/id/ENSGALP00010030884.1" } ] } }, { "isoform_ac": "A0A8V0ZHV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82/entry#A0A8V0ZHV3-1", "sequence": { "sequence": "MPGWRKSLALCLQRMQEDDDGPYSKGSKDSGGMDSALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDQLNVGDYIKSVNGINLTKLRHDEIISLLKNVGERVVLEVEYELPPAVPESSAGIIPKTIEVSLYKEGNSFGFVLRGGAHEDWHKSRPLVLTYVRPGGPADREGSLKIGDRLLSVDGIPLHSVTHADALNILRQCSQEALFQIEYDVTIMDTVTNASGPLLVEIAKTPGSTLGITLTTSTHRNKQVIVIDKIKPASVVDRCGALHVGDHILSIDGTSTEHCSLLEATQLLAATSENVKLEILPVHQSRLPLKPPETVKVQKSDHHHCWDPCVNYCHTHHPGHCKTPTWNQTSGQDYCKSLVAANFSSPTMNAQGFPCQNSNTLPRSSHPMSPRTTMLRRRQKKKEHKSSLSLASSTVGPGGQIVHTETTEVVLRGDPLNGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALTNKVVLEIEFDVAESVIPSSGTFHVKLPKKRGVELGITISSASRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCSMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAIIYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNVSLKGKPLSEAIHLLQMAGETVTLKIKKQMEKSYPKKSGSINEVSDPEDELTDSQKTSKLSEMYSTTIPSVDSAMESWDGSGIDAGYGSQGTYIPQAAGIALHPHEWRHSRQKSSTPPADPRKSYPYMDGSFSEDDWDKPSRYPNRQNGLETTHEDSFWRVFGEALEDLETCGQSELLREIEASIMTGSVHNLGLEGSKLLLDSVNPSGLSPLRKANSGCDNGHTESSSSPAKKNERNLDMKKMEKEMQEIMSPTPLEFHKMTLHKDPESEDFGFSVSDGLLEKGVYVNMVRPDGPADQCGLKPYDRVLQVNRVRTRDFDCCLTVPLISEAGDKLDLVISRNPLAANAPPEGKRELLAQAACAEVKASIQTV", "length": 1086, "header": "tr|A0A8V0ZHV3-1|A0A8V0ZHV3_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 2 OS=Gallus gallus OX=9031 GN=GRIP2 PE=4 SV=1 CANONICAL=A0A8V0ZC82-1" }, "locus": { "chromosome": "12", "start_pos": 11415297, "end_pos": 11200984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051783.1", "url": "https://www.ensembl.org/id/ENSGALT00010051783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030889.1", "url": "https://www.ensembl.org/id/ENSGALP00010030889.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-416993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416993", "resource": "Reactome", "description": "Trafficking of GluR2-containing AMPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MFS5-1", "protein_name": "Glutamate receptor interacting protein 2", "gene_name": "GRIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLAVSLKWRLGVVRRRPKDNGPYTKGDKDTGAADGALARRRQSIPEEFRGVTTVELTKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIHLTRLRHDEIITLLKNVGERVVLEVEFELPPPAPENNPGIVSKTVDVSLLKEGNSFGFVLRGGAHEDGHKSRPLVLTYVRPGGPADREGSLKVGDRLLSVDGIPLQGASHATALATLRQCSHEALFQVEYDVTIPDTVANASGPLIVEITKTPGSALGISLTTGSHRNKPVITIDRIKPASVVDRSGALHAGDHILSIDGTSTEHCSLLEATKLLASVSEKVRLEILPAPQSRRPLKPSEAVKVQRSEQPHRWDPCVPSCHSPRPGRCRTPTWAAPAGQDQNRSLSSSPFSSPTVNHTFSCTNPSTLPRGSQPMSPRTTMGRRRPRRREHKSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLVISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILRQCEDLVKLKIRKDEDNSDEQETTGAISYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLTPRKSGSLSEASDADEDPPEALKGGLLAARSSPTVPSVDSAVESWGGSATEGGFGGPGSYTAQTAARAMTPQEWRSSWLRSSPPLTEPRRTSYTPGPADESVPEEEEEDWEPPTSPAPGPSREEGFWRTFGEALEDLESCGQSELLRELEASIMTGTVQSVAPEGRPGHRPWRRSRELRASPEEMQELLLPTPVEMHKVTLHKDPVRSDFGFSVSDGLLEKGVYVHTVRPDGPAQRGGLRPFDRLLQVNHVRTRDLDCCLTVPLLADAGDVVELIISRNPLAQTSRSPRAPGPSGPRML", "length": 1046 }, "evidence": [ { "id": "A0A8V0ZC82", "url": "https://omabrowser.org/oma/group/A0A8V0ZC82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3XA20-1", "protein_name": "Glutamate receptor interacting protein 2", "gene_name": "Grip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGADGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIHLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPSPQSRRPLKPPEAVRIQRSEQLHRWDPSAPSCHSPRPSHCRAPTWAAGGPDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEDAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLATRFSPAVPSVDSAVESWGSSATDGGFGGTGSYTPQVAVRSVTPQEWRPSRLKSSPPPLEPRRTSYTPGPSDESFPEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVHSVAVDGRPGSRPWRRSREVRTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQLGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQML", "length": 1042 }, "evidence": [ { "id": "A0A8V0ZC82", "url": "https://omabrowser.org/oma/group/A0A8V0ZC82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0E4-1", "protein_name": "Glutamate receptor-interacting protein 2", "gene_name": "GRIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCGLSRETPGEADDGPYSKGGKDAGGADVSLACRRQSIPEEFRGITVVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNIGDYIRSVNGIHLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDGHKSRPLVLTYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATLRQCSHEALFQVEYDVATPDTVANASGPLMVEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHCSLLEATKLLASISEKVRLEILPVPQSQRPLRPSEAVKVQRSEQLHRWDPCVPSCHSPRPGHCRMPTWATPAGQDQSRSLSSTPFSSPTLNHAFSCNNPSTLPRGSQPMSPRTTMGRRRQRRREHKSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSGTFHVKLPKKRSVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILRQCEDLVKLKIRKDEDNSDELETTGAVSYTVELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRKSGSLSETSDADEDPADALKGGLPAARFSPAVPSVDSAVESWDSSATEGGFGGPGSYTPQAAARGTTPQERRPGWLRGSPPPTEPRRTSYTPTPADESFPEEEEEDDWEPPTSPAPGPAREEGFWRMFGEALEDLESCGQSELLRELEASIMTGTVQRVALEGRPGHRPWQRGREVRASPAEMEELLLPTPLEMHKVTLHKDPMRHDFGFSVSDGLLEKGVYVHTVRPDGPAHRGGLQPFDRVLQVNHVRTRDFDCCLAVPLLAEAGDVLELIISRKPHTAHSSRAPRSPGPSSPRML", "length": 1043 }, "evidence": [ { "id": "A0A8V0ZC82", "url": "https://omabrowser.org/oma/group/A0A8V0ZC82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W450-1", "protein_name": "Glutamate receptor interacting protein, isoform A", "gene_name": "Grip", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLWKSKKPIGGCVPGKSAALKQDQQQQQQQQQESHNNSFNGHHHPPTDTALAPMLSVDRAMSPAQSEDSGLAPERGTTYATITLPRNALHLAITFAERNDLSYPPVVGSLNPVGHAADFLAPGDRLHQIDGISTIGLSNQKVMNMLCAGGSDACPAIVEIEYSLPECTVSQNSLCVTSKLAQITVERESGCLGLTLRGGADYPLIVTHVRPHGPVYKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSVEFSMGPLLIEIERPMNDKLGLVLCNYTAAVPASGSGSSTPSSGEKIEESAGVFIASILPASIADRCGALSVGDQVLSIDDTMIEHTAFSPDEVMTILDTSTGRGYTQMQIMPAHALARRGHTTLGSPKYSFSTLESRKSSTAGRQRQRFARKSSLPLENPACGTPGSTGGSMGTGGIHGSSSLGMGLGLCRAESFPVLLDCSHGAGIILSETVSGSGGSGAVAIAQIVPDSVADRSGCIQAGDRIVAINKMYSLDAAAMRQLLEGGSSRNGASNGTPANWLELEIEFDMPDAVVPASGVFSVKLLRAGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRSGDILLAVDQHPVQHFNVDALLKEEGRSQNPSHSSSDFTTLTIKRIVLPDFLPMSSPIYSNCPASGINLGMGMGVSTSTDHDLYSSAYVTAGKYADCVSLKSRTPQPDYFRVPSMDDASLQSVQLRSGSGSNGGNQAANSWSTGVNSRSYVAPPNTQSLTTELPEEEDEQEQMYPGYELNRYASVDCTALPPPMENKVYGSAASSSSKSSGSSLHQIIFTVRLEPKGGLLGITLAGSEDITKSITISGLVEGGIAHKNGQIHVGDQLLAIDEHSVQGMPLSHATSLLQNLGDLVDLKILRSHDLANGSHLPQTQAIYAKVQRRPRSPSANTEASKESGSGNANGGGAVNGNSGSGKPRVFHVTLYKDKVYDDYGFSVSDGLYERGVFINRIRSGGPADMCGLLKPFDRIMQVNEMKTQDFDCCLTVPLIAAAGDKIEMIMQRSE", "length": 1058 }, "evidence": [ { "id": "A0A8V0ZC82", "url": "https://omabrowser.org/oma/group/A0A8V0ZC82/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTW1-1", "protein_name": "Glutamate receptor-interacting protein 2", "gene_name": "Grip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGTDGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEAVRIQRSEQLHHWDPCVPSCHSPRPSHCRAPTWAPGGQDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWRSSRLKSSPPPLEPRRTSYTPGPTDESFPEEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVQSVAVDGRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQMI", "length": 1043 }, "evidence": [ { "id": "A0A8V0ZC82", "url": "https://omabrowser.org/oma/group/A0A8V0ZC82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC82" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 136, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 714, "end_pos": 716 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE01-1", "uniprot_ac": "A0A8V0ZE01", "uniprot_id": "A0A8V0ZE01_CHICK", "mass": { "chemical_mass": 23898.0, "monoisotopic_mass": 23898.0 }, "refseq": {}, "gene_names": [ { "name": "NPM2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ] } ], "protein_names": [ { "name": "Nucleophosmin/nucleoplasmin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01", "locus": { "chromosome": "22", "start_pos": 1512833, "end_pos": 1514724, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020292", "url": "https://www.ensembl.org/id/ENSGALG00010020292" } ] } } ], "crossref": [ { "id": "A0A8V0ZE01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000050870", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000050870", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107050133", "url": "https://www.ncbi.nlm.nih.gov/gene/107050133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107050133", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107050133", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQECYES", "url": "https://omabrowser.org/oma/group/GQECYES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U959", "url": "https://www.orthodb.org/?gene=A0A3Q2U959", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE01", "url": "https://www.orthodb.org/?gene=A0A8V0ZE01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK09", "url": "https://www.orthodb.org/?gene=A0A8V0ZK09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22747", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22747", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22747:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22747:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U959", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U959", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U959-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U959-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGVSDKSEPPPRCSSSPSPPPSPGAMSLTESIETKSEKPMSFIWGCELSSERSSYTFQVPEEWQCEQQLALRTICLGEKARDEFHVVEVVPAEEGAVPLATLKPSVLPMATLVGVELTPPVTFRLRAGSGPVYISGQHVSLVPDLSWEEEEEEEEEAEEEEEEETPEVPPRGQVAKKGHAAKKRRLEKEAELNNASPEEPLPSKGRGGGRGRKAAARK", "length": 220, "header": "tr|A0A8V0ZE01-1|A0A8V0ZE01_CHICK Isoform 1 of Nucleophosmin/nucleoplasmin 2 OS=Gallus gallus OX=9031 GN=NPM2 PE=3 SV=1 CANONICAL=A0A8V0ZE01-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U959-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01/entry#A0A3Q2U959-1", "sequence": { "sequence": "MSLTESIETKSEKPMSFIWGCELSSERSSYTFQVPEEWQCEQQLALRTICLGEKARDEFHVVEVVPAEEGAVPLATLKPSVLPMATLVGVELTPPVTFRLRAGSGPVYISGQHVSLVPDLSWEEEEEEEEEAEEEEEEETPEVPPRGQVAKKGHAAKKRRLEKEAELNNASPEEPLPSKGRGGGRGRKAAARK", "length": 193, "header": "tr|A0A3Q2U959-1|A0A8V0ZE01_CHICK Computationally mapped isoform of Nucleophosmin/nucleoplasmin 2 OS=Gallus gallus OX=9031 GN=NPM2 PE=3 SV=1 CANONICAL=A0A8V0ZE01-1" }, "locus": { "chromosome": "22", "start_pos": 1514441, "end_pos": 1513010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048952.1", "url": "https://www.ensembl.org/id/ENSGALT00010048952.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028935.1", "url": "https://www.ensembl.org/id/ENSGALP00010028935.1" } ] } }, { "isoform_ac": "A0A8V0ZE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01/entry#A0A8V0ZE01-1", "sequence": { "sequence": "MGGGVSDKSEPPPRCSSSPSPPPSPGAMSLTESIETKSEKPMSFIWGCELSSERSSYTFQVPEEWQCEQQLALRTICLGEKARDEFHVVEVVPAEEGAVPLATLKPSVLPMATLVGVELTPPVTFRLRAGSGPVYISGQHVSLVPDLSWEEEEEEEEEAEEEEEEETPEVPPRGQVAKKGHAAKKRRLEKEAELNNASPEEPLPSKGRGGGRGRKAAARK", "length": 220, "header": "tr|A0A8V0ZE01-1|A0A8V0ZE01_CHICK Isoform 1 of Nucleophosmin/nucleoplasmin 2 OS=Gallus gallus OX=9031 GN=NPM2 PE=3 SV=1 CANONICAL=A0A8V0ZE01-1" }, "locus": { "chromosome": "22", "start_pos": 1514522, "end_pos": 1513010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048962.1", "url": "https://www.ensembl.org/id/ENSGALT00010048962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028941.1", "url": "https://www.ensembl.org/id/ENSGALP00010028941.1" } ] } }, { "isoform_ac": "A0A8V0ZK09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01/entry#A0A8V0ZK09-1", "sequence": { "sequence": "MSLTESIETKSEKPMSFIWGCELSSERSSYTFQVPEEWQCEQQLALRTICLGEKARDEFHVVEVVPAEEGAVPLATLKPSVLPMATLVGVELTPPVTFRLRAGSGPVYISGQHVSLVPDLSWEEEEEEEEEAEEEEEEETPEVPPRGQVAKKGHAAKEQRLPRGAPAQQGPRRRPWQEGSSEEMSCNGCSPGFAAGEIRNLLFFPQ", "length": 206, "header": "tr|A0A8V0ZK09-1|A0A8V0ZK09_CHICK Computationally mapped isoform of Nucleophosmin/nucleoplasmin 2 OS=Gallus gallus OX=9031 GN=NPM2 PE=3 SV=1 CANONICAL=A0A8V0ZE01-1" }, "locus": { "chromosome": "22", "start_pos": 1514441, "end_pos": 1512848, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048958.1", "url": "https://www.ensembl.org/id/ENSGALT00010048958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028939.1", "url": "https://www.ensembl.org/id/ENSGALP00010028939.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107050133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107050133", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGI0-1", "protein_name": "Nucleoplasmin-2", "gene_name": "Npm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHHSTSSGTETTTKIMLWGGELSQEKQICTFRPQGEKDNCKLLLSTICLGEKAKEEVNRVEILPPANQEDRKSPVTIASLKASVLPMVTVTGVKLCPPVTFRLRAGSGPVFLSGRECYETSDASWEEEEEAEEEEDEEEEEDEEEDVDISIEESPIKQVKRMAPQKQANLAKKKRLDKEEEEEAVRPSPQDKNPWKKVKSTPKPKKSASKK", "length": 212 }, "evidence": [ { "id": "A0A8V0ZE01", "url": "https://omabrowser.org/oma/group/A0A8V0ZE01/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D0K1J0-1", "protein_name": "Nucleoplasmin-2", "gene_name": "NPM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRSRTSSTSEKATVALLWGCELNQEKPTCTFRPQKEGKQDCKLLLSTICLGEKAREEMNLVEILPPAGQDNRKRKAITLASLRASVLPMVVLVGLELSPPVTFQLRAGSGPVFLSGQEYYDPSDLSWEEDEEEEEGPEEEEEEEDDDDDDDDDDIDVSLEKETPVKQVKRLAPQKQTSAAKVREEHHPPPWARPPELSALRPGPDLPGAQREPALAPSLTHTPHNACVWFLEEKGGKRRGSEVTVNLAKTFKLVEVLST", "length": 260 }, "evidence": [ { "id": "A0A8V0ZE01", "url": "https://omabrowser.org/oma/group/A0A8V0ZE01/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N327-1", "protein_name": "Nucleoplasmin-2", "gene_name": "NPM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRSPISSTSEKETVSLLWGCELNQERPTWTFKPQKVGKQDCVLLLSTISLGEKAKEEVNVVEILPSASPDDKKRRPLTLASLRASVLPMVVLGLEFSPPVTFQLRAGSGPVFLCGQEHYNRFWEEVEEEDDDLEEEEDDDDDDEDIDMFLEETPVKQVKRLAPQKQTSAAKEKKVEKKEEAVRHHLKGSPAGKPKKPGR", "length": 200 }, "evidence": [ { "id": "A0A8V0ZE01", "url": "https://omabrowser.org/oma/group/A0A8V0ZE01/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q80W85-1", "protein_name": "Nucleoplasmin-2", "gene_name": "Npm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRHSTSSVTETTAKNMLWGSELNQEKQTCTFRGQGEKKDSCKLLLSTICLGEKAKEEVNRVEVLSQEGRKPPITIATLKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLECYETSDLTWEDDEEEEEEEEEEDEDEDADISLEEIPVKQVKRVAPQKQMSIAKKKKVEKEEDETVVRPSPQDKSPWKKEKSTPRAKKPVTKK", "length": 207 }, "evidence": [ { "id": "A0A8V0ZE01", "url": "https://omabrowser.org/oma/group/A0A8V0ZE01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SE8-1", "protein_name": "Nucleoplasmin-2", "gene_name": "NPM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK", "length": 214 }, "evidence": [ { "id": "A0A8V0ZE01", "url": "https://omabrowser.org/oma/group/A0A8V0ZE01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "positive regulation of meiotic nuclear division", "id": "GO:0045836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "oocyte differentiation", "id": "GO:0009994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009994", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE01" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": 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"uniprotkb_annotation": "Nucleoplasmin core", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 141, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ] } ], "protein_names": [ { "name": "TAFA chemokine like family member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM19A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZCJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "771511", "url": "https://www.ncbi.nlm.nih.gov/gene/771511", 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"Protein Classification", "Other" ] }, { "id": "A0A8V0Z595", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z595", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z595-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z595-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5A0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELRLSEYLMDGGPQSEENVLKCRKAYLQPQMGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVLQKWWCHMNPCLDGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "length": 194, "header": "tr|A0A8V0ZCJ4-1|A0A8V0ZCJ4_CHICK Isoform 1 of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z595-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0Z595-1", "sequence": { "sequence": "MGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEDTG", "length": 120, "header": "tr|A0A8V0Z595-1|A0A8V0Z595_CHICK Computationally mapped isoform of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15422855, "end_pos": 15383879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048147.1", "url": "https://www.ensembl.org/id/ENSGALT00010048147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028405.1", "url": "https://www.ensembl.org/id/ENSGALP00010028405.1" } ] } }, { "isoform_ac": "A0A8V0Z5A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0Z5A0-1", "sequence": { "sequence": "MGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEGNAVAKNKPVGPTGTVVCATALLGC", "length": 142, "header": "tr|A0A8V0Z5A0-1|A0A8V0ZCJ4_CHICK Computationally mapped isoform of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15422855, "end_pos": 15376041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048159.1", "url": "https://www.ensembl.org/id/ENSGALT00010048159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028410.1", "url": "https://www.ensembl.org/id/ENSGALP00010028410.1" } ] } }, { "isoform_ac": "A0A8V0ZB37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0ZB37-1", "sequence": { "sequence": "GPGCAAAPRPSPAGRAAPSPSSATFPAARRPPGAERHGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVLQKWWCHMNPCLDGEDCKVLPDYSGWSCSSGNKVKTTKISEWFRLEGKPGGHHVQPRCSVRGVIGR", "length": 159, "header": "tr|A0A8V0ZB37-1|A0A8V0ZCJ4_CHICK Computationally mapped isoform of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15444654, "end_pos": 15376114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048153.1", "url": "https://www.ensembl.org/id/ENSGALT00010048153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028407.1", "url": "https://www.ensembl.org/id/ENSGALP00010028407.1" } ] } }, { "isoform_ac": "A0A8V0ZB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0ZB42-1", "sequence": { "sequence": "MGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVLQKWWCHMNPCLDGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "length": 162, "header": "tr|A0A8V0ZB42-1|A0A8V0ZCJ4_CHICK Computationally mapped isoform of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15422855, "end_pos": 15376106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048164.1", "url": "https://www.ensembl.org/id/ENSGALT00010048164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028412.1", "url": "https://www.ensembl.org/id/ENSGALP00010028412.1" } ] } }, { "isoform_ac": "A0A8V0ZCJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0ZCJ4-1", "sequence": { "sequence": "MEELRLSEYLMDGGPQSEENVLKCRKAYLQPQMGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVLQKWWCHMNPCLDGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "length": 194, "header": "tr|A0A8V0ZCJ4-1|A0A8V0ZCJ4_CHICK Isoform 1 of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15424904, "end_pos": 15376106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048141.1", "url": "https://www.ensembl.org/id/ENSGALT00010048141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028403.1", "url": "https://www.ensembl.org/id/ENSGALP00010028403.1" } ] } }, { "isoform_ac": "A0A8V0ZCK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4/entry#A0A8V0ZCK0-1", "sequence": { "sequence": "MGIWNNYEKHTEIIVFDWNKILAKSPRMRFCAKSMLLSDWLFLVYVLMVCCKLLSASSHHPRGHTGQHQVKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVLQKWWCHMNPCLDGEDCKVLPDYSGWSCSSGNKVKTTKISEWFRLEGKPGGHHVQPRCSVRGVIGR", "length": 187, "header": "tr|A0A8V0ZCK0-1|A0A8V0ZCK0_CHICK Computationally mapped isoform of TAFA chemokine like family member 4 OS=Gallus gallus OX=9031 GN=FAM19A4 PE=3 SV=1 CANONICAL=A0A8V0ZCJ4-1" }, "locus": { "chromosome": "12", "start_pos": 15422855, "end_pos": 15376114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048154.1", "url": "https://www.ensembl.org/id/ENSGALT00010048154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028408.1", "url": "https://www.ensembl.org/id/ENSGALP00010028408.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771511", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B8Y1-1", "protein_name": "TAFA chemokine like family member 4", "gene_name": "TAFA4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKSPRMRVWARSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHTGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "length": 140 }, "evidence": [ { "id": "A0A8V0ZCJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7TPG5-1", "protein_name": "Chemokine-like protein TAFA-4", "gene_name": "Tafa4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRVCAKWVLLSRWLVLTYVLMVCCKLMSASSQHLRGHAGHHLIKPGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEAAIVIEKWWCHMNPCLEGEDCKVLPDSSGWSCSSGNKVKTTKVTR", "length": 135 }, "evidence": [ { "id": "A0A8V0ZCJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LR4-1", "protein_name": "Chemokine-like protein TAFA-4", "gene_name": "TAFA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "length": 140 }, "evidence": [ { "id": "A0A8V0ZCJ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" }, { "name": "macrophage chemotaxis", "id": "GO:0048246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCD0-1", "uniprot_ac": "A0A8V0ZCD0", "uniprot_id": "A0A8V0ZCD0_CHICK", "mass": { "chemical_mass": 26553.0, "monoisotopic_mass": 26553.0 }, "refseq": {}, "gene_names": [ { "name": "C7orf62", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C7orf62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZCD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5F8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6H2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCD0", "url": "https://www.orthodb.org/?gene=A0A8V0ZCD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCD4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34035:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34035:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5F8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AEPGYGGGGASGRAAQLAGAAAVGAEESPDRAAAVAASHPAGYHRELFEVASEYEQVSGLLLLSSSQVLHVVESCCSTIHFLIRALASLQKQGPSALLQEIKVLVVAHNIPSRQFPKWDVAVVTSPVTHSEDSMQSQSIEEVVTECLTLLVNVADYVLKSAEDDSKANSDSLCVLPPELLIPAATIGYLSKAEECASPVDFLRMYLSPVQPALDSVWKTCSSAGVRTWSRKHSWTLERKELGSCGCFRL", "length": 249, "header": "tr|A0A8V0ZCD0-1|A0A8V0ZCD0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C7orf62 PE=4 SV=1 CANONICAL=A0A8V0ZCD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0/entry#A0A8V0Z5F8-1", "sequence": { "sequence": "AARAALSCACCAELRRAALSCACCAELRVLRSARSVASRCSACWSWPGCAKRWRRRRWQSCCSTIHFLIRALASLQKQGPSALLQEIKVLVVAHNIPSRQFPKWDVAVVTSPVTHSEDSMQSQSIEEVVTECLTLLVNVADYVLKSAEDDSKANSDSLCVLPPELLIPAATIGYLSKAEECASPVDFLRMYLSPVQPALDSEVVWPIPLHLSA", "length": 213, "header": "tr|A0A8V0Z5F8-1|A0A8V0ZCD0_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C7orf62 PE=4 SV=1 CANONICAL=A0A8V0ZCD0-1" }, "locus": { "chromosome": "14", "start_pos": 6566686, "end_pos": 6563746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044003.1", "url": "https://www.ensembl.org/id/ENSGALT00010044003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026163.1", "url": "https://www.ensembl.org/id/ENSGALP00010026163.1" } ] } }, { "isoform_ac": "A0A8V0Z6H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0/entry#A0A8V0Z6H2-1", "sequence": { "sequence": "AARAALCPQCRVPLQRLLVVARLREEVEAEEVAGYHRELFEVASEYEQVSGLLLLSSSQVLHVVESCCSTIHFLIRALASLQKQGPSALLQEIKVLVVAHNIPSRQFPKWDVAVVTSPVTHSEDSMQSQSIEEVVTECLTLLVNVADYVLKSAEDDSKANSDSLCVLPPELLIPAATIGYLSKAEECASPVDFLRMYLSPVQPALDSEVVWPIPLHLSA", "length": 219, "header": "tr|A0A8V0Z6H2-1|A0A8V0ZCD0_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C7orf62 PE=4 SV=1 CANONICAL=A0A8V0ZCD0-1" }, "locus": { "chromosome": "14", "start_pos": 6566686, "end_pos": 6563823, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044010.1", "url": "https://www.ensembl.org/id/ENSGALT00010044010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026167.1", "url": "https://www.ensembl.org/id/ENSGALP00010026167.1" } ] } }, { "isoform_ac": "A0A8V0ZCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0/entry#A0A8V0ZCD0-1", "sequence": { "sequence": "AEPGYGGGGASGRAAQLAGAAAVGAEESPDRAAAVAASHPAGYHRELFEVASEYEQVSGLLLLSSSQVLHVVESCCSTIHFLIRALASLQKQGPSALLQEIKVLVVAHNIPSRQFPKWDVAVVTSPVTHSEDSMQSQSIEEVVTECLTLLVNVADYVLKSAEDDSKANSDSLCVLPPELLIPAATIGYLSKAEECASPVDFLRMYLSPVQPALDSVWKTCSSAGVRTWSRKHSWTLERKELGSCGCFRL", "length": 249, "header": "tr|A0A8V0ZCD0-1|A0A8V0ZCD0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C7orf62 PE=4 SV=1 CANONICAL=A0A8V0ZCD0-1" }, "locus": { "chromosome": "14", "start_pos": 6566437, "end_pos": 6563378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044007.1", "url": "https://www.ensembl.org/id/ENSGALT00010044007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026165.1", "url": "https://www.ensembl.org/id/ENSGALP00010026165.1" } ] } }, { "isoform_ac": "A0A8V0ZCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0/entry#A0A8V0ZCD4-1", "sequence": { "sequence": "PFLGSASAARPPPAAPGAEPGYGGGGASGRAAQLAGAAAVGAEESPDRAAAVAASHPAGYHRELFEVASEYEQVSGLLLLSSSQVLHVVESCCSTIHFLIRALASLQKQGPSALLQEIKVLVVAHNIPSRQFPKWDVAVVTSPVTHSEDSMQSQSIEEVVTECLTLLVNVADYVLKSAEDDSKANSDSLCVLPPELLIPAATIGYLSKAEECASPVDFLRMYLSPVQPALDSEVVWPIPLHLSA", "length": 244, "header": "tr|A0A8V0ZCD4-1|A0A8V0ZCD4_CHICK Computationally mapped isoform of TEX47 protein OS=Gallus gallus OX=9031 GN=C7orf62 PE=4 SV=1 CANONICAL=A0A8V0ZCD0-1" }, "locus": { "chromosome": "14", "start_pos": 6566686, "end_pos": 6563327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044014.1", "url": "https://www.ensembl.org/id/ENSGALT00010044014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026170.1", "url": "https://www.ensembl.org/id/ENSGALP00010026170.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "blue light photoreceptor activity", "id": "GO:0009882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCC7-1", "uniprot_ac": "A0A8V0ZCC7", "uniprot_id": "A0A8V0ZCC7_CHICK", "mass": { "chemical_mass": 369947.0, "monoisotopic_mass": 369947.0 }, "refseq": {}, "gene_names": [ { "name": "CDH23", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ] } ], "protein_names": [ { "name": "Cadherin-23", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#names_and_taxonomy" } ] }, { "name": "Otocadherin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N9#function" }, { "database": "UniProtKB", "id": "ARBA00057485", "url": "https://www.uniprot.org/uniprotkb/ARBA00057485#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ02#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDH23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7", "locus": { "chromosome": "6", "start_pos": 12645886, "end_pos": 12517290, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020041", "url": "https://www.ensembl.org/id/ENSGALG00010020041" } ] } } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5N9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBH8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCC7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ02", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24025:SF18", "url": 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"A0A8V0Z5N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGCLPRSPGCGRDSVSPLLFDLHSTGPSVPMHRERFGMPRGGTMKRHTAASNLLLSLLVLELVPLGQGNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGTVNIQVGDVNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKNKPLSTLANLAITITDVQDMDPIFINLPYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPFYSSGFILTVKGTELNDDRTPSNATVTTTFNILVIDVNDNAPEFNSSEYSVAIPELAQVGFALPLFIQVQDKDEGPNSVFEVYLVGNNSNHFIISPTSIQGKADIRVRVAVPLDFETIPRYEFSLFANESIPEHVGFARVKISLINENDNRPVFSKALYNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGEETAGRIRINVLDVNDNVPTFQKEAYLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFREYFDITVSEGYGVISVNHPLDYEQVVNGVIYLTVMAKDAGNPPLNSTVPVTIEVFDENDNPPTFSKPSYVIAVMEDIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVGHHQKTGIAMVNITLLDINDNYPTWKDAPYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPNKFYSLNSTSGKIRTSGVQLDRENPNPQEAELMRRIVVSVTDCGRPPLRATSSATVFVNLLDLNDNDPTFQNLPFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESPTFLPAIYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTGNRRTGTATVYVTVLDVNDNRPIFLQSSYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLMRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDEVPVFTQRQYNRLGLRETAGIGTSVAVVRATDRDTGNGGLVSYQILSGAEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEAVQFSNSSYEAVIMENIPLGSEVLRVQARSIDNLNQITYKFDPNTNAQALSLFKINGITGVITVKGQVDREKGDFYTLTVVADDGGPKVDSTVVTITVLDENDNSPQFDITSDSAVSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVNDNPPIIDSPLGYNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRPSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDNAPVFQQQLYEVTLDEGPATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEISHGRYTLVVTATDQCPIASRRLTSTTTVLVNLNDINDNCPTFPRPYEGPFDVTEGQPGPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKDAELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDNDPVLLNLPMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRDFDLLVISIADENDNHPLFTQSSYQAEVMENSPAGTPVTMLNGPILALDSDQGSNAVVTYQLLGTSPDLFIINNRTGVVSVKPGGVIDREALLDPLLEFTLIALDTGGLNSTASLTVTILDDNDNRPVFQPVSITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDRFLIDATTGVIRVANLSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDCRPEFINPIQTVSVPESATPGTVVAEVTAIDRDLHPRLEYYLLEIVARDDTDALVSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASEVTDRSVSVPNAKLTVNVLDVNDNTPRFRPFGVTYFTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLEDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDNNPIFSQPSYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSLGDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNPGDISSNRRENSVQVLITVLDINDFRPQFSKSQFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSIEGPGAEAFKINKDSGLITSRRRLQSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDIDDNEPIFLRPSRDSPQYQALSVPEHSQPGTVVGNVTGAVDADEGSNAIVYYFIAAGNRESNFQLSREGKLQVLRDLDREKEPYYSIIVKASSQRNWSPPRSQRAGRAQHWDLSTDLTLQEVRIFLDDINDQSPQFTKSEYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGIRYIKQHSNDSEEVANIFSIGTLDGILRTFDLFTAYNPGYFVVDIMASDLVGHNDTAIVGIYILRDDQRVKIIINEIPDKVRQFEEEFISLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRETNRILDVERVIQMIDENKEQLRNLFRNYNVLDVQPAITAHAPDDLSALQMAIIVLAVLLFLAAMLFILMNWYYRTVHKRKLKAIVAGSTGNRGFMDIMDMPNTNKYSFDGANPVWLDPFCRTMELAAQAEHEDDLPENLSEITDLWNSPARTHGTFGREPSAAKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKLIQKDLEEDEERSPSQGSLRFRHKQPVELKGPDGIHVVHGSTGTLLASDLNSLPEDDQKVLGRSLETLTADCGAYDHNARTESAKSTPLHKMREVIMESPLEITEL", "length": 3363, "header": "tr|A0A8V0ZCC7-1|A0A8V0ZCC7_CHICK Isoform 1 of Cadherin-23 OS=Gallus gallus OX=9031 GN=CDH23 PE=4 SV=1 CANONICAL=A0A8V0ZCC7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#A0A8V0Z5N9-1", "sequence": { "sequence": "MKRHTAASNLLLSLLVLELVPLGQGNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGTVNIQVGDVNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKNKPLSTLANLAITITDVQDMDPIFINLPYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPFYSSGFILTVKGTELNDDRTPSNATVTTTFNILVIDVNDNAPEFNSSEYSVAIPELAQVGFALPLFIQVQDKDEGPNSVFEVYLVGNNSNHFIISPTSIQGKADIRVRVAVPLDFETIPRYEFSLFANESIPEHVGFARVKISLINENDNRPVFSKALYNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGEETAGRIRINVLDVNDNVPTFQKEAYLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFREYFDITVSEGYGVISVNHPLDYEQVVNGVIYLTVMAKDAGNPPLNSTVPVTIEVFDENDNPPTFSKPSYVIAVMEDIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVGHHQKTGIAMVNITLLDINDNYPTWKDAPYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPNKFYSLNSTSGKIRTSGVQLDRENPNPQEAELMRRIVVSVTDCGRPPLRATSSATVFVNLLDLNDNDPTFQNLPFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESPTFLPAIYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTGNRRTGTATVYVTVLDVNDNRPIFLQSSYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLMRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDEVPVFTQRQYNRLGLRETAGIGTSVAVVRATDRDTGNGGLVSYQILSGAEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEAVQFSNSSYEAVIMENIPLGSEVLRVQARSIDNLNQITYKFDPNTNAQALSLFKINGITGVITVKGQVDREKGDFYTLTVVADDGGPKVDSTVVTITVLDENDNSPQFDITSDSAVSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVNDNPPIIDSPLGYNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRPSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDNAPVFQQQLYEVTLDEGPATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEISHGRYTLVVTATDQCPIASRRLTSTTTVLVNLNDINDNCPTFPRPYEGPFDVTEGQPGPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKDAELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDNDPVLLNLPMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRDFDLLVISIADENDNHPLFTQSSYQAEVMENSPAGTPVTMLNGPILALDSDQGSNAVVTYQLLGTSPDLFIINNRTGVVSVKPGGVIDREALLDPLLEFTLIALDTGGLNSTASLTVTILDDNDNRPVFQPVSITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDRFLIDATTGVIRVANLSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDCRPEFINPIQTVSVPESATPGTVVAEVTAIDRDLHPRLEYYLLEIVARDDTDALVSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASEVTDRSVSVPNAKLTVNVLDVNDNTPRFRPFGVTYFTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLEDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDNNPIFSQPSYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSLGDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNPGDISSNRRENSVQVLITVLDINDFRPQFSKSQFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSIEGPGAEAFKINKDSGLITSRRRLQSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDIDDNEPIFLRPSRDSPQYQALSVPEHSQPGTVVGNVTGAVDADEGSNAIVYYFIAAGNRESNFQLSREGKLQVLRDLDREKEPYYSIIVKASSQRNWSPPRSQRAGRAQHWDLSTDLTLQEVRIFLDDINDQSPQFTKSEYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGIRYIKQHSNDSEEVANIFSIGTLDGILRTFDLFTAYNPGYFVVDIMASDLVGHNDTAIVGIYILRDDQRVKIIINEIPDKVRQFEEEFISLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRETNRILDVERVIQMIDENKEQLRNLFRNYNVLDVQPAITAHAPDDLSALQMAIIVLAVLLFLAAMLFILMNWYYRTVHKRKLKAIVAGSTGNRGFMDIMDMPNTNKYSFDGANPVWLDPFCRTMELAAQAEHEDDLPENLSEITDLWNSPARTHGTFGREPSAAKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKLIQKDLEEDEERSPSQGSLRFRHKQPVELKGPDGIHVVHGSTGTLLASDLNSLPEDDQKVLGRSLETLTADCGAYDHNARTESAKSTPLHKMREVIMESPLEITEL", "length": 3318, "header": "tr|A0A8V0Z5N9-1|A0A8V0ZCC7_CHICK Computationally mapped isoform of Cadherin-23 OS=Gallus gallus OX=9031 GN=CDH23 PE=4 SV=1 CANONICAL=A0A8V0ZCC7-1" }, "locus": { "chromosome": "6", "start_pos": 12645171, "end_pos": 12524477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048447.1", "url": "https://www.ensembl.org/id/ENSGALT00010048447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028561.1", "url": "https://www.ensembl.org/id/ENSGALP00010028561.1" } ] } }, { "isoform_ac": "A0A8V0ZBH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#A0A8V0ZBH8-1", "sequence": { "sequence": "MASGCLPRSPGCGRDSVSPLLFDLHSTGPSVPMHRERFGMPRGGTMKRHTAASNLLLSLLVLELVPLGQGNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGTVNIQVGDVNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKNKPLSTLANLAITITDVQDMDPIFINLPYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPFYSSGFILTVKGTELNDDRTPSNATVTTTFNILVIDVNDNAPEFNSSEYSVAIPELAQVGFALPLFIQVQDKDEGPNSVFEVYLVGNNSNHFIISPTSIQGKADIRVRVAVPLDFETIPRYEFSLFANESIPEHVGFARVKISLINENDNRPVFSKALYNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGEETAGRIRINVLDVNDNVPTFQKEAYLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFREYFDITVSEGYGVISVNHPLDYEQVVNGVIYLTVMAKDAGNPPLNSTVPVTIEVFDENDNPPTFSKPSYVIAVMEDIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVGHHQKTGIAMVNITLLDINDNYPTWKDAPYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPNKFYSLNSTSGKIRTSGVQLDRENPNPQEAELMRRIVVSVTDCGRPPLRATSSATVFVNLLDLNDNDPTFQNLPFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESPTFLPAIYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTGNRRTGTATVYVTVLDVNDNRPIFLQSSYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLMRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDEVPVFTQRQYNRLGLRETAGIGTSVAVVRATDRDTGNGGLVSYQILSGAEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEAVQFSNSSYEAVIMENIPLGSEVLRVQARSIDNLNQITYKFDPNTNAQALSLFKINGITGVITVKGQVDREKGDFYTLTVVADDGGPKVDSTVVTITVLDENDNSPQFDITSDSAVSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVNDNPPIIDSPLGYNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRPSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDNAPVFQQQLYEVTLDEGPATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEISHGRYTLVVTATDQCPIASRRLTSTTTVLVNLNDINDNCPTFPRPYEGPFDVTEGQPGPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKDAELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDNDPVLLNLPMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRDFDLLVISIADENDNHPLFTQSSYQAEVMENSPAGAVKIKNPLNRELVATYEVTISVHDNASEVTDRSVSVPNAKLTVNVLDVNDNTPRFRPFGVTYFTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLEDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDNNPIFSQPSYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSLGDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNPGDISSNRRENSVQVLITVLDINDFRPQFSKSQFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSIEGPGAEAFKINKDSGLITSRRRLQSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDIDDNEPIFLRPSRDSPQYQALSVPEHSQPGTVVGNVTGAVDADEGSNAIVYYFIAAGNRESNFQLSREGKLQVLRDLDREKEPYYSIIVKASSQRNWSPPRSQRAGRAQHWDLSTDLTLQEVRIFLDDINDQSPQFTKSEYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGIRYIKQHSNDSEEVANIFSIGTLDGILRTFDLFTAYNPGYFVVDIMASDLVGHNDTAIVGIYILRDDQRVKIIINEIPDKVRQFEEEFISLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRETNRILDVERVIQMIDENKEQLRNLFRNYNVLDVQPAITAHAPDDLSALQMAIIVLAVLLFLAAMLFILMNWYYRTVHKRKLKAIVAGSTGNRGFMDIMDMPNTNKYSFDGANPVWLDPFCRTMELAAQAEHEDDLPENLSEITDLWNSPARTHGTFGREPSAAKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKLIQKDLEEDEERSPSQGSLRFRHKQPVELKGPDGIHVVHGSTGTLLASDLNSLPEDDQKVLGRSLETLTADCGAYDHNARTESAKSTPLHKMREVIMESPLEITEL", "length": 3100, "header": "tr|A0A8V0ZBH8-1|A0A8V0ZBH8_CHICK Computationally mapped isoform of Cadherin-23 OS=Gallus gallus OX=9031 GN=CDH23 PE=4 SV=1 CANONICAL=A0A8V0ZCC7-1" }, "locus": { "chromosome": "6", "start_pos": 12645171, "end_pos": 12519035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048437.1", "url": "https://www.ensembl.org/id/ENSGALT00010048437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028557.1", "url": "https://www.ensembl.org/id/ENSGALP00010028557.1" } ] } }, { "isoform_ac": "A0A8V0ZCC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#A0A8V0ZCC7-1", "sequence": { "sequence": "MASGCLPRSPGCGRDSVSPLLFDLHSTGPSVPMHRERFGMPRGGTMKRHTAASNLLLSLLVLELVPLGQGNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGTVNIQVGDVNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKNKPLSTLANLAITITDVQDMDPIFINLPYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPFYSSGFILTVKGTELNDDRTPSNATVTTTFNILVIDVNDNAPEFNSSEYSVAIPELAQVGFALPLFIQVQDKDEGPNSVFEVYLVGNNSNHFIISPTSIQGKADIRVRVAVPLDFETIPRYEFSLFANESIPEHVGFARVKISLINENDNRPVFSKALYNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGEETAGRIRINVLDVNDNVPTFQKEAYLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFREYFDITVSEGYGVISVNHPLDYEQVVNGVIYLTVMAKDAGNPPLNSTVPVTIEVFDENDNPPTFSKPSYVIAVMEDIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVGHHQKTGIAMVNITLLDINDNYPTWKDAPYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPNKFYSLNSTSGKIRTSGVQLDRENPNPQEAELMRRIVVSVTDCGRPPLRATSSATVFVNLLDLNDNDPTFQNLPFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESPTFLPAIYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTGNRRTGTATVYVTVLDVNDNRPIFLQSSYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLMRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDEVPVFTQRQYNRLGLRETAGIGTSVAVVRATDRDTGNGGLVSYQILSGAEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEAVQFSNSSYEAVIMENIPLGSEVLRVQARSIDNLNQITYKFDPNTNAQALSLFKINGITGVITVKGQVDREKGDFYTLTVVADDGGPKVDSTVVTITVLDENDNSPQFDITSDSAVSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVNDNPPIIDSPLGYNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRPSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDNAPVFQQQLYEVTLDEGPATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEISHGRYTLVVTATDQCPIASRRLTSTTTVLVNLNDINDNCPTFPRPYEGPFDVTEGQPGPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKDAELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDNDPVLLNLPMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRDFDLLVISIADENDNHPLFTQSSYQAEVMENSPAGTPVTMLNGPILALDSDQGSNAVVTYQLLGTSPDLFIINNRTGVVSVKPGGVIDREALLDPLLEFTLIALDTGGLNSTASLTVTILDDNDNRPVFQPVSITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDRFLIDATTGVIRVANLSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDCRPEFINPIQTVSVPESATPGTVVAEVTAIDRDLHPRLEYYLLEIVARDDTDALVSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASEVTDRSVSVPNAKLTVNVLDVNDNTPRFRPFGVTYFTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLEDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDNNPIFSQPSYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSLGDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNPGDISSNRRENSVQVLITVLDINDFRPQFSKSQFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSIEGPGAEAFKINKDSGLITSRRRLQSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDIDDNEPIFLRPSRDSPQYQALSVPEHSQPGTVVGNVTGAVDADEGSNAIVYYFIAAGNRESNFQLSREGKLQVLRDLDREKEPYYSIIVKASSQRNWSPPRSQRAGRAQHWDLSTDLTLQEVRIFLDDINDQSPQFTKSEYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGIRYIKQHSNDSEEVANIFSIGTLDGILRTFDLFTAYNPGYFVVDIMASDLVGHNDTAIVGIYILRDDQRVKIIINEIPDKVRQFEEEFISLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRETNRILDVERVIQMIDENKEQLRNLFRNYNVLDVQPAITAHAPDDLSALQMAIIVLAVLLFLAAMLFILMNWYYRTVHKRKLKAIVAGSTGNRGFMDIMDMPNTNKYSFDGANPVWLDPFCRTMELAAQAEHEDDLPENLSEITDLWNSPARTHGTFGREPSAAKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKLIQKDLEEDEERSPSQGSLRFRHKQPVELKGPDGIHVVHGSTGTLLASDLNSLPEDDQKVLGRSLETLTADCGAYDHNARTESAKSTPLHKMREVIMESPLEITEL", "length": 3363, "header": "tr|A0A8V0ZCC7-1|A0A8V0ZCC7_CHICK Isoform 1 of Cadherin-23 OS=Gallus gallus OX=9031 GN=CDH23 PE=4 SV=1 CANONICAL=A0A8V0ZCC7-1" }, "locus": { "chromosome": "6", "start_pos": 12645171, "end_pos": 12519035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048424.1", "url": "https://www.ensembl.org/id/ENSGALT00010048424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028548.1", "url": "https://www.ensembl.org/id/ENSGALP00010028548.1" } ] } }, { "isoform_ac": "A0A8V0ZJ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7/entry#A0A8V0ZJ02-1", "sequence": { "sequence": "MKRHTAASNLLLSLLVLELVPLGQGNRLPYFINYFFDTYLLINEDTPVGSSVTQLLARDLDNDPLVFGVVGEEASRFFAVESVTGVVWLRQPLDRETKSEFTVEFSVSDSQGVIKGTVNIQVGDVNDNAPRFHNQPYSVRIPENTPVGTPIFIVNATDPDQGAGGSVLYSFQPPSSFFAIDSGRGIVTVIRELDYEVTQAYQLQVNATDQDKNKPLSTLANLAITITDVQDMDPIFINLPYSTNIYENSPPGTTVRMITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGPLDRENPFYSSGFILTVKGTELNDDRTPSNATVTTTFNILVIDVNDNAPEFNSSEYSVAIPELAQVGFALPLFIQVQDKDEGPNSVFEVYLVGNNSNHFIISPTSIQGKADIRVRVAVPLDFETIPRYEFSLFANESIPEHVGFARVKISLINENDNRPVFSKALYNVSLPENATVGTTVLQVHATDNDVGSYGKVSYFFSDDPDRFSLDKDTGVILLMARLDFETMQRYTLTVIARDGGGEETAGRIRINVLDVNDNVPTFQKEAYLGALRENEPSVTQVVRLRASDEDSPPNNQITYSIVHASAFREYFDITVSEGYGVISVNHPLDYEQVVNGVIYLTVMAKDAGNPPLNSTVPVTIEVFDENDNPPTFSKPSYVIAVMEDIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSHFRINARSGEITTTSLLDREAKSEYILIVRAVDGGVGHHQKTGIAMVNITLLDINDNYPTWKDAPYFINLVEMTPPNSDVTTVVAVDPDLGENGTVVYSIRPPNKFYSLNSTSGKIRTSGVQLDRENPNPQEAELMRRIVVSVTDCGRPPLRATSSATVFVNLLDLNDNDPTFQNLPFIAEISEGLPAGTSVFQVLAIDLDEGPNGWVTYRMQVGMPRMDFLINSTSGLIISTTVLDRERITEYYLRVVASDAGTPSKSSTSTLTVKVLDVNDESPTFLPAIYNVSLPENVARDFKVVRLNCTDADVGLNAELSYFITGGNQDGKFSVGFRDGVVRTVVSLDRETVASYALILEAIDNGPTGNRRTGTATVYVTVLDVNDNRPIFLQSSYEASVPEDIPAASSIVQVKATDADEGVNGRVWYRIVKGNEHNNFRINPSSGLLMRGVRPLDREQNSSHVLEVEAYNTEHGPMRSSVRVIVYVEDVNDEVPVFTQRQYNRLGLRETAGIGTSVAVVRATDRDTGNGGLVSYQILSGAEGKFEIDESTGLITTIDYLDYETKTSYLMNVSATDQAPPNNQGFCSVYVSLLNELDEAVQFSNSSYEAVIMENIPLGSEVLRVQARSIDNLNQITYKFDPNTNAQALSLFKINGITVTITVLDENDNSPQFDITSDSAVSVPEDSVVGRRVAVVLARDPDAGSNGQVTFSLTAGNVGQAFEIRTTNDTYGEVLVARPLDRELLDHYTLRIQASDGGVPPRRKEHTLRVTVLDVNDNPPIIDSPLGYNVSVSENVGGGTAVVQVRATDRDAGLNSVLSYYITHGNEDLTFRMDRVTGEIATRPSPPDRERQSSYCLLVTVEDEGTPSLSATTKVFVTILDENDNAPVFQQQLYEVTLDEGPATLNATLVTVQALDRDEGPNSTVTYAITEGNILGTFYINSTTGQIRTLKELDYEISHGRYTLVVTATDQCPIASRRLTSTTTVLVNLNDINDNCPTFPRPYEGPFDVTEGQPGPRIWTFLAHDGDSGPGGQVEYSIIAGDPLGEFVISPVEGELRVRKDAELDRENIPFYNLTISARDRGVPPLSSTMLVGVRVLDINDNDPVLLNLPMNITLSEHAPVSSFVTRILAQDADQGPNALLTFDITAGNKESAFYINSTTGIIYVNRPLDREQVAEYRLTITVKDNPENIRNARRDFDLLVISIADENDNHPLFTQSSYQAEVMENSPAGTPVTMLNGPILALDSDQGSNAVVTYQLLGTSPDLFIINNRTGVVSVKPGGVIDREALLDPLLEFTLIALDTGGLNSTASLTVTILDDNDNRPVFQPVSITARLRENSPPGFSVLQVTATDADSGLNKQLDYRIEGGGQDRFLIDATTGVIRVANLSIDREERDAYQLTVVAVDQGTPALSGTATVSIFIDDVNDCRPEFINPIQTVSVPESATPGTVVAEVTAIDRDLHPRLEYYLLEIVARDDTDALVSDQQGTFTVDFRTGAVKIKNPLNRELVATYEVTISVHDNASEVTDRSVSVPNAKLTVNVLDVNDNTPRFRPFGVTYFTERILEGATQGTTLISISAVDPDKGANGQITYELLDLSPEGYACLEDQSAGKVVANRTVDYEEVQWLNFTVRASDNGSPRRSAEIPVYLQIVDINDNNPIFSQPSYQKAVFEDVPLGTVILRVKATDADSGRFAVIQYSLGDGEGKFGINPDTGDIYILSALDREKKDHYTLTAVARDNPGDISSNRRENSVQVLITVLDINDFRPQFSKSQFSTSVYENEPAGTSVITMTATDLDEGDNGVVTYSIEGPGAEAFKINKDSGLITSRRRLQSYERFNLTVVATDKGRPPLWGTTMLHIEVIDINDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVLYSLLKTGAGNKDWEYFSIDAVSGLIQTAMRLDREKQAEYNLIIVASDQGQPAYETMQPLQVALDDIDDNEPIFLRPSRDSPQYQALSVPEHSQPGTVVGNVTGAVDADEGSNAIVYYFIAAGNRESNFQLSREGKLQVLRDLDREKEPYYSIIVKASSQRNWSPPRSQRAGRAQHWDLSTDLTLQEVRIFLDDINDQSPQFTKSEYTAGVATDAKVGSELIRVLAVDADVGNNSLVLYSILGIRYIKQHSNDSEEVANIFSIGTLDGILRTFDLFTAYNPGYFVVDIMASDLVGHNDTAIVGIYILRDDQRVKIIINEIPDKVRQFEEEFISLLSNITGAIVNTDDVQFHVDKKGRVNFAQTELLIHVVNRETNRILDVERVIQMIDENKEQLRNLFRNYNVLDVQPAITAHAPDDLSALQMAIIVLAVLLFLAAMLFILMNWYYRTVHKRKLKAIVAGSTGNRGFMDIMDMPNTNKYSFDGANPVWLDPFCRTMELAAQAEHEDDLPENLSEITDLWNSPARTHGTFGREPSAAKPEDDRYLRAAIQEYDNIAKLGQIMREGPIKLIQKDLEEDEERSPSQGSLRFRHKQPVELKGPDGIHVVHGSTGTLLASDLNSLPEDDQKVLGRSLETLTADCGAYDHNARTESAKSTPLHKMREVIMESPLEITEL", "length": 3284, "header": "tr|A0A8V0ZJ02-1|A0A8V0ZJ02_CHICK Computationally mapped isoform of Cadherin-23 OS=Gallus gallus OX=9031 GN=CDH23 PE=4 SV=1 CANONICAL=A0A8V0ZCC7-1" }, "locus": { "chromosome": "6", "start_pos": 12645171, "end_pos": 12524477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048456.1", "url": "https://www.ensembl.org/id/ENSGALT00010048456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028569.1", "url": "https://www.ensembl.org/id/ENSGALP00010028569.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1015, "start_aa": "Thr", "end_pos": 1015, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1015", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2230, "start_aa": "Thr", "end_pos": 2230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2230", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "kinocilium", "id": "GO:0060091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "cochlear hair cell ribbon synapse", "id": "GO:0098683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" }, { "name": "photoreceptor ribbon synapse", "id": "GO:0098684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098684", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73621", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73621", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-74259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z5T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE11", "url": "https://www.uniprot.org/uniprotkb/F1NE11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE11-1", "url": "https://www.uniprot.org/uniprotkb/F1NE11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCPHSPWRSVCRISALPVLPQPCSASWGRSAIRFVTLQQCGKCPPASLVSQCRAERAHCWELLPPCVRVHYLSLHPHALSCSSRCLLFWVSVAAGILGMFQLRRGSVPDPGPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 435, "header": "tr|A0A8V0ZCP6-1|A0A8V0ZCP6_CHICK Isoform 1 of 5'-nucleotidase, cytosolic IA OS=Gallus gallus OX=9031 GN=NT5C1A PE=4 SV=1 CANONICAL=A0A8V0ZCP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6/entry#A0A8V0Z5T9-1", "sequence": { "sequence": "MEPPGTAGAPGAAGRPWDEAKAFYDNLTPKKKPKSPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 346, "header": "tr|A0A8V0Z5T9-1|A0A8V0ZCP6_CHICK Computationally mapped isoform of 5'-nucleotidase, cytosolic IA OS=Gallus gallus OX=9031 GN=NT5C1A PE=4 SV=1 CANONICAL=A0A8V0ZCP6-1" }, "locus": { "chromosome": "23", "start_pos": 5866819, "end_pos": 5860854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044214.1", "url": "https://www.ensembl.org/id/ENSGALT00010044214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026297.1", "url": "https://www.ensembl.org/id/ENSGALP00010026297.1" } ] } }, { "isoform_ac": "A0A8V0Z6U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6/entry#A0A8V0Z6U0-1", "sequence": { "sequence": "MGVRPCLRIAAQCWQPGRGLQMALGLLPVSTQCEPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 357, "header": "tr|A0A8V0Z6U0-1|A0A8V0ZCP6_CHICK Computationally mapped isoform of 5'-nucleotidase, cytosolic IA OS=Gallus gallus OX=9031 GN=NT5C1A PE=4 SV=1 CANONICAL=A0A8V0ZCP6-1" }, "locus": { "chromosome": "23", "start_pos": 5866139, "end_pos": 5860854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044213.1", "url": "https://www.ensembl.org/id/ENSGALT00010044213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026296.1", "url": "https://www.ensembl.org/id/ENSGALP00010026296.1" } ] } }, { "isoform_ac": "A0A8V0ZCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6/entry#A0A8V0ZCP6-1", "sequence": { "sequence": "MLCPHSPWRSVCRISALPVLPQPCSASWGRSAIRFVTLQQCGKCPPASLVSQCRAERAHCWELLPPCVRVHYLSLHPHALSCSSRCLLFWVSVAAGILGMFQLRRGSVPDPGPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 435, "header": "tr|A0A8V0ZCP6-1|A0A8V0ZCP6_CHICK Isoform 1 of 5'-nucleotidase, cytosolic IA OS=Gallus gallus OX=9031 GN=NT5C1A PE=4 SV=1 CANONICAL=A0A8V0ZCP6-1" }, "locus": { "chromosome": "23", "start_pos": 5865264, "end_pos": 5860854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044209.1", "url": "https://www.ensembl.org/id/ENSGALT00010044209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026294.1", "url": "https://www.ensembl.org/id/ENSGALP00010026294.1" } ] } }, { "isoform_ac": "F1NE11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6/entry#F1NE11-1", "sequence": { "sequence": "MGLGAAGRGGLGPEEVKQRPGGMKPRSFMGCRIKTFRRRELPVRTERCAMEPPGTAGAPGAAGRPWDEAKAFYDNLTPKKKPKSPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFLPGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEEGIAAATIFSPSKDLEVSEKQLRVAFDGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLRMECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQMFHVEGAKEMGTVAAHVPYGVAQKHKRPLQEKQPQNSK", "length": 407, "header": "tr|F1NE11-1|A0A8V0ZCP6_CHICK Computationally mapped isoform of 5'-nucleotidase, cytosolic IA OS=Gallus gallus OX=9031 GN=NT5C1A PE=4 SV=3 CANONICAL=A0A8V0ZCP6-1" }, "locus": { "chromosome": "23", "start_pos": 5866966, "end_pos": 5860854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044216.1", "url": "https://www.ensembl.org/id/ENSGALT00010044216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026299.1", "url": "https://www.ensembl.org/id/ENSGALP00010026299.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" }, { "id": "R-GGA-74259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74259", "resource": "Reactome", "description": "Purine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZYY7-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "Nt5c1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGRLGRAGGAGSLALPPGPAACLSHPGRASLPRLSSLSSLSPTLSSPARPDRIRAGTWNQGSPRRPENPDQGQRPPRCRAGRKPRRSMTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAPEMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ", "length": 454 }, "evidence": [ { "id": "A0A8V0ZCP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KFX0-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "Nt5c1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGQPREAREPGPGAETAAVPRWEEAKTFYDNLSSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKRLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADADKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRRAAAAKQSLGAQ", "length": 365 }, "evidence": [ { "id": "A0A8V0ZCP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BF39-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "NT5C1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPGEPREPREPGPGAETAAAPQWEEAKTFYDNLAPQKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPESEDLFDIVLVTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVQEAIDEGIAAATIFSPSRDVAVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTSRRTSPTKQAAPAQ", "length": 365 }, "evidence": [ { "id": "A0A8V0ZCP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SV04-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "NT5C1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPEEPRELREPGPGAETAAAPRWEEAKTFYDNLTSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYMEQGVEEYVRYQLEHENEPFSPGPISSPIQALEAVNKRLRELYPESEDLFDIVLVTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVQEAIDEGIAAATIFSPSRDVAVSQSQLRVAFDGDAVLFSDESERIVKAHGLDSFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTTPTKQAPSAQ", "length": 365 }, "evidence": [ { "id": "A0A8V0ZCP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9BXI3-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "NT5C1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ", "length": 368 }, "evidence": [ { "id": "A0A8V0ZCP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "adenosine metabolic process", "id": "GO:0046085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "AMP catabolic process", "id": "GO:0006196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006196", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "allantoin metabolic process", "id": "GO:0000255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "dAMP catabolic process", "id": "GO:0046059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "IMP catabolic process", "id": "GO:0006204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" }, { "name": "dGMP catabolic process", "id": "GO:0046055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBQ7-1", "uniprot_ac": "A0A8V0ZBQ7", "uniprot_id": "A0A8V0ZBQ7_CHICK", "mass": { "chemical_mass": 93035.0, "monoisotopic_mass": 93035.0 }, "refseq": { "ac": "XP_001233206", "name": "BRCA1-associated ATM activator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233206" }, "gene_names": [ { "name": "BRAT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ] }, { "name": "BRAT1", "type": "synonym", "evidence": [ { "id": "XP_001233206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233206" } ] } ], "protein_names": [ { "name": "BRCA1 associated ATM activator 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7/entry#names_and_taxonomy" } ] }, { "name": "BRCA1-associated ATM activator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233206" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233206.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233206" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7", "locus": { "chromosome": "14", "start_pos": 3351898, "end_pos": 3343546, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020104", "url": "https://www.ensembl.org/id/ENSGALG00010020104" } ] } } ], "crossref": [ { "id": "A0A8V0ZBQ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "769893", "url": "https://www.ncbi.nlm.nih.gov/gene/769893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769893", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IQVFTEW", "url": "https://omabrowser.org/oma/group/IQVFTEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W3", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBQ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZBQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ67", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21331:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21331:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233206", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPRGRRAMSRACARLLPRVCAALADPRQPGSDDTCLEKMLDWFRELREAEPTVKLLRDNPCLTEFFTAVLALPEPEPNVLSFTLRLAGIVAAVEDSFMHLQQLELLARLFGEDGPLNSAAWEDASVRSGWVEGVHSMVQHQSALHFICSGGGIDVIFTLQGDPSLFVASAACRLLVHLLTLSVGSELTVPLNAKDCDWPACAHMIIRHIEESLQSNSASHIKQSLKLLTSLFGSCQAPWTKVLWLGMAKQVESFLTEDSVQAQHILADLLLNMARSPVFHDTEGSFWALVTSALEHLTPVQSSPLAVGILRLHRCPQVVRIKALTVLLQPMDCILRAAFQPLEYAGLLDESVSDPSAVESLLSSKSSCASLLCQTLAHLEELLSVVFLPVNLPYASLLRSVVTILQFCNGLLIPASPLGSKISQILVGCFRVQKSALDALAALSDRKCSDTVVGSLFDVLLAYLESPNTTPTVLKKSFKAMSKWLMSLPGMSFFKNQQQTEKTLQDVFLVLQKRLCSPCWEVRDSSLEFLTNLIRNLRDHDEFRQSLLSSEVPKLTENLLEDPESYVRASAVTAMGHLAFITYFFVPESPVAGNQYNKEKTVAKLQEILSTDPEGFPRRAVMNVFTMWLKESCTGQLEETEQFVSTVVQTTAHDLDWEVKLGCLELVQIFCNHMFCRFGLPECPYAPISSAVTSSICQNEPLQIFCRANLFSFLFRSLCDCDKPVGQKACDILLALKSHFCQSSTTDLQGPGDLSAGHGIHWLQGTLRQGSLVQNFPTDDGNGVDFQDPESMMLALRTIDLVELHNDLNKCSDYVEKSPQSLLEDILATVGTAEENEADCY", "length": 842, "header": "tr|A0A8V0ZBQ7-1|A0A8V0ZBQ7_CHICK Isoform 1 of BRCA1 associated ATM activator 1 OS=Gallus gallus OX=9031 GN=BRAT1 PE=3 SV=1 CANONICAL=A0A8V0ZBQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7/entry#A0A8V0Z5W3-1", "sequence": { "sequence": "MSRACARLLPRVCAALADPRQPGSDDTCLEKMLDWFRELREAEPTVKLLRDNPCLTEFFTAVLALPEPEPNVLSFTLRLAGIVAAVEDSFMHLQQLELLARLFGEDGPLNSAAWEDASVRSGWVEGVHSMVQHQSALHFICSGGGIDVIFTLQGDPSLFVASAACRLLVHLLTLSVGSELTVPLNAKDCDWPACAHMIIRHIEESLQSNSASHIKQSLKLLTSLFGSCQAPWTKVLWLGMAKQVESFLTEDSVQAQHILADLLLNMASPQVVRIKALTVLLQPMDCILRAAFQPLEYAGLLDESVSDPSAVESLLSSKSSCASLLCQTLAHLEELLSVVFLPVNLPYASLLRSVVTILQFCNGLLIPASPLGSKISQILVGCFRVQKSALDALAALSDRKCSDTVVGSLFDVLLAYLESPNTTPTVLKKSFKAMSKWLMSLPGMSFFKNQQQTEKTLQDVFLVLQKRLCSPCWEVRDSSLEFLTNLIRNLRDHDEFRQSLLSSEVPKLTENLLEDPESYVRASAVTAMGHLAFITYFFVPESPVAGNQYNKEKTVAKLQEILSTDPEGFPRRAVMNVFTMWLKESCTGQLEETEQFVSTVVQTTAHDLDWEVKLGCLELVQIFCNHMFCRFGLPECPYAPISSAVTSSICQNEPLQIFCRANLFSFLFRSLCDCDKPVGQKACDILLALKSHFCQSSTTDLQGPGDLSAGHGIHWLQGTLRQGSLVQNFPTDDGNGVDFQDPESMMLALRTIDLVELHNDLNKCSDYVEKSPQSLLEDILATVGTAEENEADCY", "length": 794, "header": "tr|A0A8V0Z5W3-1|A0A8V0ZBQ7_CHICK Computationally mapped isoform of BRCA1 associated ATM activator 1 OS=Gallus gallus OX=9031 GN=BRAT1 PE=3 SV=1 CANONICAL=A0A8V0ZBQ7-1" }, "locus": { "chromosome": "14", "start_pos": 3351551, "end_pos": 3343834, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048556.1", "url": "https://www.ensembl.org/id/ENSGALT00010048556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028647.1", "url": "https://www.ensembl.org/id/ENSGALP00010028647.1" } ] } }, { "isoform_ac": "A0A8V0ZBQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7/entry#A0A8V0ZBQ7-1", "sequence": { "sequence": "MSPRGRRAMSRACARLLPRVCAALADPRQPGSDDTCLEKMLDWFRELREAEPTVKLLRDNPCLTEFFTAVLALPEPEPNVLSFTLRLAGIVAAVEDSFMHLQQLELLARLFGEDGPLNSAAWEDASVRSGWVEGVHSMVQHQSALHFICSGGGIDVIFTLQGDPSLFVASAACRLLVHLLTLSVGSELTVPLNAKDCDWPACAHMIIRHIEESLQSNSASHIKQSLKLLTSLFGSCQAPWTKVLWLGMAKQVESFLTEDSVQAQHILADLLLNMARSPVFHDTEGSFWALVTSALEHLTPVQSSPLAVGILRLHRCPQVVRIKALTVLLQPMDCILRAAFQPLEYAGLLDESVSDPSAVESLLSSKSSCASLLCQTLAHLEELLSVVFLPVNLPYASLLRSVVTILQFCNGLLIPASPLGSKISQILVGCFRVQKSALDALAALSDRKCSDTVVGSLFDVLLAYLESPNTTPTVLKKSFKAMSKWLMSLPGMSFFKNQQQTEKTLQDVFLVLQKRLCSPCWEVRDSSLEFLTNLIRNLRDHDEFRQSLLSSEVPKLTENLLEDPESYVRASAVTAMGHLAFITYFFVPESPVAGNQYNKEKTVAKLQEILSTDPEGFPRRAVMNVFTMWLKESCTGQLEETEQFVSTVVQTTAHDLDWEVKLGCLELVQIFCNHMFCRFGLPECPYAPISSAVTSSICQNEPLQIFCRANLFSFLFRSLCDCDKPVGQKACDILLALKSHFCQSSTTDLQGPGDLSAGHGIHWLQGTLRQGSLVQNFPTDDGNGVDFQDPESMMLALRTIDLVELHNDLNKCSDYVEKSPQSLLEDILATVGTAEENEADCY", "length": 842, "header": "tr|A0A8V0ZBQ7-1|A0A8V0ZBQ7_CHICK Isoform 1 of BRCA1 associated ATM activator 1 OS=Gallus gallus OX=9031 GN=BRAT1 PE=3 SV=1 CANONICAL=A0A8V0ZBQ7-1" }, "locus": { "chromosome": "14", "start_pos": 3351551, "end_pos": 3343810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048558.1", "url": "https://www.ensembl.org/id/ENSGALT00010048558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028649.1", "url": "https://www.ensembl.org/id/ENSGALP00010028649.1" } ] } }, { "isoform_ac": "A0A8V0ZJ67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7/entry#A0A8V0ZJ67-1", "sequence": { "sequence": "MSKWLMSLPGMSFFKNQQQTEKTLQDVFLVLQKRLCSPCWEVRDSSLEFLTNLIRNLRDHDEFRQSLLSSEVPKLTENLLEDPESYVRASAVTAMGHLAFITYFFVPESPVAGNQYNKEKTVAKLQEILSTDPEGFPRRAVMNVFTMWLKESCTGQLEETEQFVSTVVQTTAHDLDWEVKLGCLELVQIFCNHMFCRFGLPECPYAPISSAVTSSICQNEPLQIFCRANLFSFLFRSLCDCDKPVGQKACDILLALKSHFCQSSTTDLQGPGDLSAGHGIHWLQGTLRQGSLVQNFPTDDGNGVDFQDPESMMLALRTIDLVELHNDLNKCSDYVEKSPQSLLEDILATVGTAEENEADCY", "length": 361, "header": "tr|A0A8V0ZJ67-1|A0A8V0ZJ67_CHICK Computationally mapped isoform of BRCA1 associated ATM activator 1 OS=Gallus gallus OX=9031 GN=BRAT1 PE=3 SV=1 CANONICAL=A0A8V0ZBQ7-1" }, "locus": { "chromosome": "14", "start_pos": 3351551, "end_pos": 3349447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048552.1", "url": "https://www.ensembl.org/id/ENSGALT00010048552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028643.1", "url": "https://www.ensembl.org/id/ENSGALP00010028643.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769893", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769893", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSM9-1", "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "Brat1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAECSRLLPALCAVLADPRQLVADDTCLEKLLDWFKTVTEAEPSLQLLQDHPCLMELLSHVLKPQDVSPRVLSFALRLVGVFAAQEDCFQYLQQGELLLGLFGETGALSWAAWSIPSVRSGWIQGLCSLAHHPSALHFLADSGAVDTIFSLQGDPSLFVASAASQLLVHILALSMQGGAPGSPVPEAVAWPVCAQKIMNHVEESLHSKATPQVTQALNVLTTTFGRCHNPWTGVLWERLSPPVARLFERDPIPATHSLMDLLLSVARSPVLNFAACGLWEMLAQTLSRLSPTQAGPLALGTLKLQHCPQELRTQAFRVLLQPLACILKATTQAPGPPGLLDGTAGSLLTVDALLSSKSACVGLLCQTLAHLEELQMLPQCPSPWPQVPLLQAAVTILRLSDGSADPSSSAGGRLCGALGGCVRVQRAALDFLGTLSLGTSPLELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQSPHKTPSGSDLSPDALLFLGELFPILQKRLCSPCWEVRDSALEFLTHLIRDWGGQADFREALHSSEVPTLARQLLQDPESYVRASAVGAAGQLSSQGLQATPANQQGLLMDLMHILSTDSEGFPRRAVLRVFTEWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELAQVFLIQAMGQPRLHCPYTVGLPGATSSRPHLEFLQTLCRLPLFEFAFCALLDCDRPVAQKACDLLLFLRDKTVSCSNPQEAGDSPNSASVEAALQRWREGEQAQPLGDLEPEAMLAILRSLDLEGLQGRLAKSSDHVEKSPQSLLQDMLATVGVLEENEADCY", "length": 816 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N1C8-1", "protein_name": "BRCA1 associated ATM activator 1", "gene_name": "BRAT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPECARLLPALCDVLADPRQPVADDTCLEKLLDWFKAVTEAGSSLLLLQDHPCLVELLFHVLKPQDLSSRILSFVLRLAGIFAAQENCFQYLQQGELLPGLFGEPGPLGAAAWAAPSVRSGWIQGLHSLAQHPSALRFLADSGAVDTIFSLQGDPSLFVASAAGQLLVRVLDLALCGPAEGHISLQAWDWPACARKIVCHLEDCLRSEATPRVTQALHVLTTAFGHCHGLWTQGLWVQLSPLVARLLEKDPVPAPHALVDLLLSVARSSMLSSDPGLWETAAQTLSRLSPTQAGPLAAGILKLQDCPQALRIQAFGVLLQPLAFVLEATAQAPGMPGLLEGAAGDLMAVDTLPPSKSACVGLLCSALAHLELLQPLPQRPSPWPQAPLLAAVVAILRLCNGSAAPNSEAGGRLCAMLGGCVRVQRAALDFLGVLSQGLGPQELVTQVFAILLEYLVSPDSSPTVLKKAFQATLCWLLSSAAPPGCCDLEPYAQLVLGELLSVLRKRLCSPCWEVRDSGLEFLTQMTRHQGGQAGFRQALLASEVPELTRQLLQDPESYVRASAVAAVGQLSSWGLLAAPSSPEHAATPQKTPLEELLLVLTTDSEGFPRRAVMRVFTEWLRDGYADVAEDPERFVARVLQAASGDLDWEVRVQGLELALAFLEQLLGPCGPSAVAPPGALAQALQALCRVQLFEFAFRSLFDCDRPVAQKSCDLLLFLRAKAIPSSNSQEAGDGPDVTSVEAALRRWQAGEQGQPLGELAPEAVLAVLRSMDLEALQDTLAESSDHVERSPQSLLQDMLATVGVLGDNEADCY", "length": 814 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RI80-1", "protein_name": "BRCA1 associated ATM activator 1", "gene_name": "BRAT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPECSRLLPALCAVLADPRQPVADDTCLEKLLDWFKTITEAGSSLLVLQENPCLVELLFHVLKPQDLSPRVLSFSLRLAGMFAAQEDCFQYLQQGELLPRLFGEAGPLGGAAWTAPTVRSGWIQGLRSLAQHPRALPFLADCGAVDTIFSLQGDSSLFVASAAGQLLVHILDLAMRAPPRGHPGPQACDGPACAQKIVCHLEDSLRAAAAPQLTQALNVLTTTFGHCHGLWTPGLWGRLSPLVGHLLEKDPVPASHALVDLLLSVARSPVLSSESGPWETLALTLSRLSPMQAGPLALGILKLQDCPQALRTQASGVLLQPLACVLKAAVQGPGRPGLPDGAAGDSVTVDTLFSSKSACVGLLCCALAHLELLQLLPQCPSPWPQEALLEAVVTVLRFCNGSAVPASDLGGHLCATLVGCVRVQRAALDFLGTLSQRAGPQELVTQVSAVLLEYLSGPDSSPTVLKKAFQASLGWLLSSPKTPGCCDLDPHAQQFLRELLPVLQKRLCSPCWEVRDSGLEFLTQMARHWGGQAAFRQVLLASEVPRLTRQLLQDPESYVRASAVTATGQLSSWGLHAAPAGPEQPGVQQKSLLSELLHVLATDSEGFPRRAVMQVFTEWLRGGHADVAEDPEQFVAGVLQAASRDLDWEVRAQGLELALVFLEQLLGPPGVRCPYAVALPKAAPPGTLAQALQALCRVQLFEFAFRALFDCDRPVAQKSCDLLLFLKAKATSCGTPQEERDSPDVSSVEATLQKWQAGEHGHPLGDLEPAAVVAVLRSMDLEGLQDTLAESSDHVERSPQSLLQDMLATVGVLGENEADCY", "length": 822 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GVE7-1", "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "Brat1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPECSKLLPALCAVLADPRQLVADDTCLEKLLDWFKTVMETESSLHLLQDHPCLMELLSHVLKTQDVSPRVLSFVLRLVGIFAAQEDCFQYLQQGELLLGLFGETGALSWTAWNMPSVRSGWIQGLCSLAHHPSALHFLADSGAVDTIFALQGDPSLFVASAASQLLVHILALAMQGGASGSPISEAAAWPICAQKIVNHVEESLHSKATPQVTQALNVLTTTFGRCHSPWTGVLWGRLSPPVACLFERDPIPAVHSLMDLLLSVARSHVLNFAACGLWEMLAQTLSRLSPTQAGPLALGTLKLQHCPQELRTQAFGVLLQPLACILKATTQAPGPPGLLDGTAGSSLTVDALLSSKSACVGLLCQTLAHLEELQMLPQCPCPWPQVPLLGATVTILRLCDGSVDPSSSMGGRLCGTLGGCVRVQRAALDFLGTLSQGTSPLELVLEVFAVLLKTLESPESSPTVLKKAFQATLRWLQNSHKTPNCSDLSPDALLFLGELFPILQKRLCSPCWEVRDSALEFLTHLIRHWGGQADFREALHSSEVPTLARQLLQDPESYVRASAVGTAGQLSSRGLQATSASPENPLAQQGLLMDLMHILSTDSEGFPRRAVLRVFTEWLRDGHADVIRDTEWFVATVLQAVSRDLDWEVRMQGLELAQVFLIQAMGQPSLHCPYTVGLPEATSPRPHPEFLQTLCRLPLFEFAFCALLDCDRPVAQKACDLLLFLRDKTTHCSGPQEAGDSPNSASVEAVLQRWREGEQGQPLGDLEPEAMLAILRSLDLEGLQGKLAKSSDHVEKSPQSLLQDMLATVGILEENEADCY", "length": 822 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1RLU1-1", "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "brat1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGDCSSLLPAVCLVLADPKQTPPDDTSLEKLLDWFKDLHSQSNGQVLLEHQPCLLEFISSVCASKATDPAILSFTLKLTGLLAASKQDFHLLEEGGHLVCVFEREAWSVCDLWEDASVRSGWIQGLLNMLKHQQALDFICRQGLIKVILQLQNDRSLFVACLANQLLVQILKLLTPSDVTSGSDAVVSSKSSSSLDWVSVSSEITNAVVEALSSENHPQVLQGVQLLSLVLSQCEEPIRSSLWKDVLPPLEVLINRGSEPLTQPLMTVLRAAVMTPLLGQSEYKVEEFLEVMLGTGNRKEGILCATLIVKLEKCPKVLKRKAMDIILLPLQCVSTQSQDEKEVDLVLKEPLSQKALCISLLVQSLSSLAELAHKEYFEGVCIPSVTSRVVQLLRVCSGHCTSSLLHVSACTHLIGSCKIQRCGLDTLGALSVYEDNLDLRKDIFGVLLDYLKSPDSHATVLKKTFQAVLRWIGVCASFPDLLQFISNDLFPVLEKRMCDVRWEVRDSTLEFITQLTVALSDNSGFVEVLYTSGLVSILLSLLSDTEGYVRASAVTAVGEAVTSSVQQMALVSKINLLEEALAQMMIILSQDTEGFPRRAVVKTFTSWLKGSNPITALDSSLSSVLSLGGNDFDWEVKMHTLELAEALMEKMLTCCPYAVQSFSSSERTRLTQSLSKLKDLGLFDVLLNGLFDCDRPVCEKSCQLLLKLKRLNAEKADFDHDALVLKACGNRWGDEVQSRFLNKQQVKASEHVLIGGGEGTEKDLHCIKEIPLSVILQILDLDDMQRMLKLSSDHVVNSPRSLMEDILSAAQQSEENIVDCY", "length": 822 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PJG6-1", "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "BRAT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPECAQLLPALCAVLVDPRQPVADDTCLEKLLDWFKTVTEGESSVVLLQEHPCLVELLSHVLKVQDLSSGVLSFSLRLAGTFAAQENCFQYLQQGELLPGLFGEPGPLGRATWAVPTVRSGWIQGLRSLAQHPSALRFLADHGAVDTIFSLQGDSSLFVASAASQLLVHVLALSMRGGAEGQPCLPGGDWPACAQKIMDHVEESLCSAATPKVTQALNVLTTTFGRCQSPWTEALWVRLSPRVACLLERDPIPAAHSFVDLLLCVARSPVFSSSDGSLWETVARALSCLGPTHMGPLALGILKLEHCPQALRTQAFQVLLQPLACVLKATVQAPGPPGLLDGTADDATTVDTLLASKSSCAGLLCRTLAHLEELQPLPQRPSPWPQASLLGATVTVLRLCDGSAAPASSVGGHLCGTLAGCVRVQRAALDFLGTLSQGTGPQELVTQALAVLLECLESPGSSPTVLKKAFQATLRWLLSSPKTPGCSDLGPLIPQFLRELFPVLQKRLCHPCWEVRDSALEFLTQLSRHWGGQADFRCALLASEVPQLALQLLQDPESYVRASAVTAMGQLSSQGLHAPTSPEHAEARQSLFLELLHILSVDSEGFPRRAVMQVFTEWLRDGHADAAQDTEQFVATVLQAASRDLDWEVRAQGLELALVFLGQTLGPPRTHCPYAVALPEVAPAQPLTEALRALCHVGLFDFAFCALFDCDRPVAQKSCDLLLFLRDKIASYSSLREARGSPNTASAEATLPRWRAGEQAQPPGDQEPEAVLAMLRSLDLEGLRSTLAESSDHVEKSPQSLLQDMLATGGFLQGDEADCY", "length": 821 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C3R1-1", "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "Brat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPECSRLLPALCAVLADPRQLVADDTCLEKLLDWFKTVTEAESSLQLLQDHPCLMELLSHVLKPQDVSPRVLSFALRLVGVFAAQEDCFEYLQQGELLLGLFGESGAPGWAAWSIPSVRSGWIQGLCYLAHHPSALHFLADSGAVDTLFSLQGDPSLFVASAASQLLVHILALSMQGGAPGSPVPEAAAWPMCAQKIVNHVDESLHAKATPQVTQALNVLTTTFGRCHNPWTGVLWERLSPPVARLFERDPIPAVHALMDLLLSVARSPVLNFAACGLWEMLAQTLSRLSPIQAGPLALGTLKLQHCPQELRTQAFGVLLQPLACILKATTQAPGPPGLLDGTVGSLLTVDILLASKSACVGLLCQTLAHLEELQMLPQCPSPWPQVHLLQAALTILHLCDGSADPSSSAGGRLCGTLGGCVRVQRAALDFLGTLSQGTSPLELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQNPHKTPSSSDLSSDALLFLGELFPILQKRLCSPCWEVRDSALEFLTHLIRHWGGQADFREALRSSEVPTLALQLLQDPESYVRASAVGAAGQLSSQGLQAAPASPENSQAQQGLLMDLMHILSTDSEGFPRRAVLRVFTDWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELARVFLTQALGQPSLHCPYTVGLPRASSPRPHPEFLQTLCRLPLFEFAFCALLDCDRPVAQKACDLLLFLRDKTVPCSSPREAGDSPNSASVEAALQRWREGEQAQPLGDLDPEAMLAILRALDLEGLQGRLAKSSDHVEKSPQSLLQDMLATVGVLEENEADCY", "length": 822 }, "evidence": [ { "id": "A0A8V0ZBQ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZBQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" }, { "name": "integrator complex assembly", "id": "GO:0160234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribonuclease inhibitor activity", "id": "GO:0008428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008428", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 469, "end_pos": 471 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCS9-1", "uniprot_ac": "A0A8V0ZCS9", "uniprot_id": "A0A8V0ZCS9_CHICK", "mass": { "chemical_mass": 31488.0, "monoisotopic_mass": 31488.0 }, "refseq": {}, "gene_names": [ { "name": "AQP8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ] } ], "protein_names": [ { "name": "Aquaporin 8", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AQP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9", "locus": { "chromosome": "14", "start_pos": 6655163, "end_pos": 6645652, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018335", "url": "https://www.ensembl.org/id/ENSGALG00010018335" } ] } } ], "crossref": [ { "id": "A0A8V0ZCS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416566", "url": "https://www.ncbi.nlm.nih.gov/gene/416566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416566", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416566", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAMVANH", "url": "https://omabrowser.org/oma/group/PAMVANH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZCS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19139:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z5W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLFLAQSWLQHLRMWLCWVCCSASWAVFPIHFASVPLVLGGQPSTKEAMEMVDAERPPAKQNWYECYVLPCLAELLGSAAFVFIGCLSVVEDSIGTGLLQPALVHGLSIVPIVVSLGNISGAHINPVVSLGIWLVGGMKLIMLIPYCIAQLCGGILGAALTKAVASSLNFDSRVGGAFGIIRTNAQIGPALGNEIILTTFLLLVVCMTAVNGETKSPLAPVCIALTVVINIIVGGSISGPCMNPARAFGPAVIANYWLYHWVYWVGPLIGCLISSLLIRFVIGDRKIRLFLK", "length": 294, "header": "tr|A0A8V0ZCS9-1|A0A8V0ZCS9_CHICK Isoform 1 of Aquaporin 8 OS=Gallus gallus OX=9031 GN=AQP8 PE=3 SV=1 CANONICAL=A0A8V0ZCS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9/entry#A0A8V0Z5W6-1", "sequence": { "sequence": "MEMVDAERPPAKQNWYECYVLPCLAELLGSAAFVFIGCLSVVEDSIGTGLLQPALVHGLSIVPIVVSLGNISGAHINPVVSLGIWLVGGMKLIMLIPYCIAQLCGGILGAALTKAVASSLNFDSRVGGAFGIIRTNAQIGPALGNEIILTTFLLLVVCMTAVNGETKSPLAPVCIALTVVINIIVGGSISGPCMNPARAFGPAVIANYWLYHWVYWVGPLIGCLISSLLIRFVIGDRKIRLFLK", "length": 244, "header": "tr|A0A8V0Z5W6-1|A0A8V0ZCS9_CHICK Computationally mapped isoform of Aquaporin 8 OS=Gallus gallus OX=9031 GN=AQP8 PE=3 SV=1 CANONICAL=A0A8V0ZCS9-1" }, "locus": { "chromosome": "14", "start_pos": 6654721, "end_pos": 6650671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044257.1", "url": "https://www.ensembl.org/id/ENSGALT00010044257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026325.1", "url": "https://www.ensembl.org/id/ENSGALP00010026325.1" } ] } }, { "isoform_ac": "A0A8V0ZCS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9/entry#A0A8V0ZCS9-1", "sequence": { "sequence": "MLRLFLAQSWLQHLRMWLCWVCCSASWAVFPIHFASVPLVLGGQPSTKEAMEMVDAERPPAKQNWYECYVLPCLAELLGSAAFVFIGCLSVVEDSIGTGLLQPALVHGLSIVPIVVSLGNISGAHINPVVSLGIWLVGGMKLIMLIPYCIAQLCGGILGAALTKAVASSLNFDSRVGGAFGIIRTNAQIGPALGNEIILTTFLLLVVCMTAVNGETKSPLAPVCIALTVVINIIVGGSISGPCMNPARAFGPAVIANYWLYHWVYWVGPLIGCLISSLLIRFVIGDRKIRLFLK", "length": 294, "header": "tr|A0A8V0ZCS9-1|A0A8V0ZCS9_CHICK Isoform 1 of Aquaporin 8 OS=Gallus gallus OX=9031 GN=AQP8 PE=3 SV=1 CANONICAL=A0A8V0ZCS9-1" }, "locus": { "chromosome": "14", "start_pos": 6654721, "end_pos": 6645782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044259.1", "url": "https://www.ensembl.org/id/ENSGALT00010044259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026327.1", "url": "https://www.ensembl.org/id/ENSGALP00010026327.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416566", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416566", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P56404-1", "protein_name": "Aquaporin-8", "gene_name": "Aqp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGEQTPMCSMDLPEVKVKTSMAGRCRVFWYEQYVQPCIVELVGSALFIFIGCLSVIENSPNTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTVIGGLKTMLLIPYWISQLFGGLIGAALAKVVSPEERFWNASGAAFAIVQEQEQVAEALGIEIILTMLLVLAVCMGAVNEKTMGPLAPFSIGFSVIVDILAGGSISGACMNPARAFGPAVMAGYWDFHWIYWLGPLLAGLFVGLLIRLLIGDEKTRLILKSR", "length": 261 }, "evidence": [ { "id": "A0A8V0ZCS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56405-1", "protein_name": "Aquaporin-8", "gene_name": "Aqp8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGEQTPMCSMDLREIKGKETNMADSYHGMSWYEQYIQPCVVELLGSALFIFIGCLSVIENSPNTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTLVGGLKTMLLIPYWVSQLFGGMIGAALAKVVSPEERFWNASGAAFAIVQEQEQVAEALGVEIVMTMLLVLAVCMGAVNEKTMGPLAPFSIGFSVIVDILAGGGISGACMNPARAFGPAVMAGYWDFHWIYWLGPLLAGLFVGLLIRLFIGDEKTRLILKSR", "length": 263 }, "evidence": [ { "id": "A0A8V0ZCS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ZVX8-1", "protein_name": "Probable aquaporin PIP2-8", "gene_name": "PIP2-8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKEVSEEGRHGKDYVDPPPAPLLDMAELKLWSFYRAIIAEFIATLLFLYVTVATVIGHKNQTGPCGGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLPRAVAYMVAQCLGAICGVGLVKAFMMTPYKRLGGGANTVADGYSTGTALGAEIIGTFVLVYTVFSATDPKRSARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWDDHWIFWVGPFVGALAAAAYHQYILRAAAIKALASFRSNPTN", "length": 278 }, "evidence": [ { "id": "A0A8V0ZCS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCS9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "smooth endoplasmic reticulum", "id": "GO:0005790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "intracellular canaliculus", "id": "GO:0046691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "water channel activity", "id": "GO:0015250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "urea channel activity", "id": "GO:0015265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "methylammonium channel activity", "id": "GO:0015264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "regulation of cholesterol biosynthetic process", "id": "GO:0045540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "water transport", "id": "GO:0006833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006833", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "cellular detoxification", "id": "GO:1990748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990748", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "hydrogen peroxide transmembrane transport", "id": "GO:0080170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" }, { "name": "ammonium import across plasma membrane", "id": "GO:0140157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBV8-1", "uniprot_ac": "A0A8V0ZBV8", "uniprot_id": "A0A8V0ZBV8_CHICK", "mass": { "chemical_mass": 289836.0, "monoisotopic_mass": 289836.0 }, "refseq": { "ac": "XP_046755301", "name": "A-kinase anchor protein 13 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755301" }, "gene_names": [ { "name": "AKAP13", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ] }, { "name": "AKAP13", "type": "synonym", "evidence": [ { "id": "XP_046755301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755301" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 13 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_046755301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755301" } ] }, { "name": "A-kinase anchoring protein 13", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755301" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKAP13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8", "locus": { "chromosome": "10", "start_pos": 13988550, "end_pos": 14179010, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020117", "url": "https://www.ensembl.org/id/ENSGALG00010020117" } ] } } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20878", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20878", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415502", "url": "https://www.ncbi.nlm.nih.gov/gene/415502", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z609", "url": "https://www.orthodb.org/?gene=A0A8V0Z609", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z616", "url": "https://www.orthodb.org/?gene=A0A8V0Z616", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z621", "url": "https://www.orthodb.org/?gene=A0A8V0Z621", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBT3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046755301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z609", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z609", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z609-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z609-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z616", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z616", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z616-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z616-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z621", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z621", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z621-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z621-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLNPQQAPLYGDSVITVQLTEEDKVEDDVVFYLIFTGSTVQHCTSTRKINPGSLETISPGHDCCETVKVALCASKEGRPVLVVAEESFKFIQDEAYDAAQFLATYAGNQQALNFTRFLDQSRPPAADVDILDEKVALAFRHLKLPSEWNVLGTDQSLNENIPRETLMHFAVRQGLLRLTWFLLQQPGGRGALSIHNRDGATPVSLALERGYQKLHQLLTEEEAAEPDSWSTLSHTVHTGDYCVKHHQQLDVYTLTAETKERTKASLESDIRQLRMHMQSHQHMSSRKRTKTVLGASGNSCGNGAEPVGHSTASSQSLGEMPGEGRKESPSDVLHLDIGQLSDQTHQEDECSSGSLITRVINAPNGSLGLEVVESPECSCESKNTVTLCEKEEEGPASAQSSGTLSDENGCTVSPCAGINGAVNLPSCGNTNEEAGMTSAGVVLDQAGLCSKDSTHQEVGAAEERAAESTVAAVETAGEAPASREGVDVAMGQTECRNCAGAADRAPGQQQVEDGNAEIPPTRTADPEEPLPAEEEPTSAAQPLLDGFNGTECAGGEDANVGVVPVCDSTNANVDTDVSVGLCKSGDNHEAGLSGTDLVNNGVLESQGGACVKERQRVTASTRAPLPAVNGVKVPACAPMFPDVESQDSSESVEPEGQVKVGSTNGKSSSPFLEDSLETDGLDAKAENGNIGGTEQSSEKPTHCQGSSDIAECTGEAMEGSGAHNEEPVGTDTSSSREGGSVDSADRAQEVASCCPPVDQTTVNDEMGDKLKLDGTQGSVQEPRLLPLEDASTFSAGKEPPKAEERAESASGQGMPHPDAGDLAVGRTGDAAVAPPGQEAPLCSNDPVLPPCTKGAECTEDNFVGTPFVIRNEESKQKQEVAAAGSAELAAPHGQERGGVAGVLEDYAGAPGPPKQSLQPRAEGDTAKPEREASDSSQEQVLSENLLVTVVKSFVGSAERPAASSDVGAGLKELGPNQAGTAGAGDSIMQGTGPAAGSNPCPDAGLPQECGPSLQHVSPRSSTPELKDALEMEAPSLAFEAEEALQIAAITSITGYEEEQGEMESVLPRATLQPIAEEPTCDSDSSSDTVGQGGDGDSAPTSTAAQGLVTAQPEGKQSQGISEPTPSPCSSGFNAVESPEHVGVKSSVSADDGSSLDKVPKMVKSFDAVVFAAETPSSPGLPAEGKVGPEPQPAVDVAAGLDGEADLRSSARKDVSQAIRGAKPATGKLEMKTEDEVDFMKDPRESAAREEAINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKQHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSSMRVLGDGIKKPPIHRRSLSWCPSGVQFAAMGPDFNCRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 2672, "header": "tr|A0A8V0ZBV8-1|A0A8V0ZBV8_CHICK Isoform 1 of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z609-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0Z609-1", "sequence": { "sequence": "MKLNPQQAPLYGDSVITVQLTEEDKVEDDVVFYLIFTGSTVQHCTSTRKINPGSLETISPGHDCCETVKVALCASKEGRPVLVVAEESFKFIQDEAYDAAQFLATYAGNQQALNFTRFLDQSRPPAADVDILDEKVALAFRHLKLPSEWNVLGTDQSLNENIPRETLMHFAVRQGLLRLTWFLLQQPGGRGALSIHNRDGATPVSLALERGYQKLHQLLTEEEAAEPDSWSTLSHTVHTGDYCVKHHQQLDVYTLTAETKERTKASLESDIRQLRMHMQSHQHMSSRKRTKTVLGASGNSCGNGAEPVGHSTASSQSLGEMPGEGRKESPSDVLHLDIGQLSDQTHQEDECSSGSLITRVINAPNGSLGLEVVESPECSCESKNTVTLCEKEEEGPASAQSSGTLSDENGCTVSPCAGINGAVNLPSCGNTNEEAGMTSAGVVLDQAGLCSKDSTHQEVGAAEERAAESTVAAVETAGEAPASREGVDVAMGQTECRNCAGAADRAPGQQQVEDGNAEIPPTRTADPEEPLPAEEEPTSAAQPLLDGFNGTECAGGEDANVGVVPVCDSTNANVDTDVSVGLCKSGDNHEAGLSGTDLVNNGVLESQGGACVKERQRVTASTRAPLPAVNGVKVPACAPMFPDVESQDSSESVEPEGQVKVGSTNGKSSSPFLEDSLETDGLDAKAENGNIGGTEQSSEKPTHCQGSSDIAECTGEAMEGSGAHNEEPVGTDTSSSREGGSVDSADRAQEVASCCPPVDQTTVNDEMGDKLKLDGTQGSVQEPRLLPLEDASTFSAGKEPPKAEERAESASGQGMPHPDAGDLAVGRTGDAAVAPPGQEAPLCSNDPVLPPCTKGAECTEDNFVGTPFVIRNEESKQKQEVAAAGSAELAAPHGQERGGVAGVLEDYAGAPGPPKQSLQPRAEGDTAKPEREASDSSQEQVLSENLLVTVVKSFVGSAERPAASSDVGAGLKELGPNQAGTAGAGDSIMQGTGPAAGSNPCPDAGLPQECGPSLQHVSPRSSTPELKDALEMEAPSLAFEAEEALQIAAITSITGYEEEQGEMESVLPRATLQPIAEEPTCDSDSSSDTVGQGGDGDSAPTSTAAQGLVTAQPEGKQSQGISEPTPSPCSSGFNAVESPEHVGVKSSVSADDGSSLDKVPKMVKSFDAVVFAAETPSSPGLPAEGKVGPEPQPAVDVAAGLDGEADLRSSARKDVSQAIRGAKPATGKLEMKTEDEVDFMKDPRESAAREEAINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKQHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 2633, "header": "tr|A0A8V0Z609-1|A0A8V0ZBV8_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14129568, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048601.1", "url": "https://www.ensembl.org/id/ENSGALT00010048601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028692.1", "url": "https://www.ensembl.org/id/ENSGALP00010028692.1" } ] } }, { "isoform_ac": "A0A8V0Z616-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0Z616-1", "sequence": { "sequence": "MKLNPQQAPLYGDSVITVQLTEEDKVEDDVVFYLIFTGSTVQHCTSTRKINPGSLETISPGHDCCETVKVALCASKEGRPVLVVAEESFKFIQDEAYDAAQFLATYAGNQQALNFTRFLDQSRPPAADVDILDEKVALAFRHLKLPSEWNVLGTDQSLNENIPRETLMHFAVRQGLLRLTWFLLQQPGGRGALSIHNRDGATPVSLALERGYQKLHQLLTEEEAAEPDSWSTLSHTVHTGDYCVKHHQQLDVYTLTAETKERTKASLESDIRQLRMHMQSHQHMSSRKRTKTVLGASGNSCGNGAEPVGHSTASSQSLGEMPGEGRKESPSDVLHLDIGQLSDQTHQEDECSSGSLITRVINAPNGSLGLEVVESPECSCESKNTVTLCEKEEEGPASAQSSGTLSDENGCTVSPCAGINGAVNLPSCGNTNEEAGMTSAGVVLDQAGLCSKDSTHQEVGAAEERAAESTVAAVETAGEAPASREGVDVAMGQTECRNCAGAADRAPGQQQVEDGNAEIPPTRTADPEEPLPAEEEPTSAAQPLLDGFNGTECAGGEDANVGVVPVCDSTNANVDTDVSVGLCKSGDNHEAGLSGTDLVNNGVLESQGGACVKERQRVTASTRAPLPAVNGVKVPACAPMFPDVESQDSSESVEPEGQVKVGSTNGKSSSPFLEDSLETDGLDAKAENGNIGGTEQSSEKPTHCQGSSDIAECTGEAMEGSGAHNEEPVGTDTSSSREGGSVDSADRAQEVASCCPPVDQTTVNDEMGDKLKLDGTQGSVQEPRLLPLEDASTFSAGKEPPKAEERAESASGQGMPHPDAGDLAVGRTGDAAVAPPGQEAPLCSNDPVLPPCTKGAECTEDNFVGTPFVIRNEESKQKQEVAAAGSAELAAPHGQERGGVAGVLEDYAGAPGPPKQSLQPRAEGDTAKPEREASDSSQEQVLSENLLVTVVKSFVGSAERPAASSDVGAGLKELGPNQAGTAGAGDSIMQGTGPAAGSNPCPDAGLPQECGPSLQHVSPRSSTPELKDALEMEAPSLAFEAEEALQIAAITSITGYEEEQGEMESVLPRATLQPIAEEPTCDSDSSSDTVGQGGDGDSAPTSTAAQGLVTAQPEGKQSQGISEPTPSPCSSGFNAVESPEHVGVKSSVSADDGSSLDKVPKMVKSFDAVVFAAETPSSPGLPAEGKVGPEPQPAVDVAAGLDGEADLRSSARKDVSQAIRGAKPATGKLEMKTEDEVDFMKDPRESAAREEAINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKQHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSLSWCPSGVQFAAMGPDFNCRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 2654, "header": "tr|A0A8V0Z616-1|A0A8V0ZBV8_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14129568, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048606.1", "url": "https://www.ensembl.org/id/ENSGALT00010048606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028697.1", "url": "https://www.ensembl.org/id/ENSGALP00010028697.1" } ] } }, { "isoform_ac": "A0A8V0Z621-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0Z621-1", "sequence": { "sequence": "MKLNPQQAPLYGDSVITVQLTEEDKVEDDVVFYLIFTGSTVQHCTSTRKINPGSLETISPGHDCCETVKVALCASKEGRPVLVVAEESFKFIQDEAYDAAQFLATYAGNQQALNFTRFLDQSRPPAADVDILDEKVALAFRHLKLPSEWNVLGTDQSLNENIPRETLMHFAVRQGLLRLTWFLLQQPGGRGALSIHNRDGATPVSLALERGYQKLHQLLTEEEAAEPDSWSTLSHTVHTGDYCVKHHQQLDVYTLTAETKERTKASLESDIRQLRMHMQSHQHMSSRKRTKTVLGASGNSCGNGAEPVGHSTASSQSLGEMPGEGRKESPSDVLHLDIGQLSDQTHQEDECSSGSLITRVINAPNGSLGLEVVESPECSCESKNTVTLCEKEEEGPASAQSSGTLSDENGCTVSPCAGINGAVNLPSCGNTNEEAGMTSAGVVLDQAGLCSKDSTHQEVGAAEERAAESTVAAVETAGEAPASREGVDVAMGQTECRNCAGAADRAPGQQQVEDGNAEIPPTRTADPEEPLPAEEEPTSAAQPLLDGFNGTECAGGEDANVGVVPVCDSTNANVDTDVSVGLCKSGDNHEAGLSGTDLVNNGVLESQGGACVKERQRVTASTRAPLPAVNGVKVPACAPMFPDVESQDSSESVEPEGQVKVGSTNGKSSSPFLEDSLETDGLDAKAENGNIGGTEQSSEKPTHCQGSSDIAECTGEAMEGSGAHNEEPVGTDTSSSREGGSVDSADRAQEVASCCPPVDQTTVNDEMGDKLKLDGTQGSVQEPRLLPLEDASTFSAGKEPPKAEERAESASGQGMPHPDAGDLAVGRTGDAAVAPPGQEAPLCSNDPVLPPCTKGAECTEDNFVGTPFVIRNEESKQKQEVAAAGSAELAAPHGQERGGVAGVLEDYAGAPGPPKQSLQPRAEGDTAKPEREASDSSQEQVLSENLLVTVVKSFVGSAERPAASSDVGAGLKELGPNQAGTAGAGDSIMQGTGPAAGSNPCPDAGLPQECGPSLQHVSPRSSTPELKDALEMEAPSLAFEAEEALQIAAITSITGYEEEQGEMESVLPRATLQPIAEEPTCDSDSSSDTVGQGGDGDSAPTSTAAQGLVTAQPEGKQSQGISEPTPSPCSSGFNAVESPEHVGVKSSVSADDGSSLDKVPKMVKSFDAVVFAAETPSSPGLPAEGKVGPEPQPAVDVAAGLDGEADLRSSARKDVSQAIRGAKPATGKLEMKTEDEVDFMKDPRESAAREEAINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSSMRVLGDGIKKPPIHRRSLSWCPSGVQFAAMGPDFNCRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 2671, "header": "tr|A0A8V0Z621-1|A0A8V0ZBV8_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14129568, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048611.1", "url": "https://www.ensembl.org/id/ENSGALT00010048611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028702.1", "url": "https://www.ensembl.org/id/ENSGALP00010028702.1" } ] } }, { "isoform_ac": "A0A8V0ZBT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0ZBT3-1", "sequence": { "sequence": "MYERHKRRYSLCDISKVDRTVDVVLLKINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSLSWCPSGVQFAAMGPDFNCRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 1428, "header": "tr|A0A8V0ZBT3-1|A0A8V0ZBT3_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14053221, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048583.1", "url": "https://www.ensembl.org/id/ENSGALT00010048583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028674.1", "url": "https://www.ensembl.org/id/ENSGALP00010028674.1" } ] } }, { "isoform_ac": "A0A8V0ZBV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0ZBV8-1", "sequence": { "sequence": "MKLNPQQAPLYGDSVITVQLTEEDKVEDDVVFYLIFTGSTVQHCTSTRKINPGSLETISPGHDCCETVKVALCASKEGRPVLVVAEESFKFIQDEAYDAAQFLATYAGNQQALNFTRFLDQSRPPAADVDILDEKVALAFRHLKLPSEWNVLGTDQSLNENIPRETLMHFAVRQGLLRLTWFLLQQPGGRGALSIHNRDGATPVSLALERGYQKLHQLLTEEEAAEPDSWSTLSHTVHTGDYCVKHHQQLDVYTLTAETKERTKASLESDIRQLRMHMQSHQHMSSRKRTKTVLGASGNSCGNGAEPVGHSTASSQSLGEMPGEGRKESPSDVLHLDIGQLSDQTHQEDECSSGSLITRVINAPNGSLGLEVVESPECSCESKNTVTLCEKEEEGPASAQSSGTLSDENGCTVSPCAGINGAVNLPSCGNTNEEAGMTSAGVVLDQAGLCSKDSTHQEVGAAEERAAESTVAAVETAGEAPASREGVDVAMGQTECRNCAGAADRAPGQQQVEDGNAEIPPTRTADPEEPLPAEEEPTSAAQPLLDGFNGTECAGGEDANVGVVPVCDSTNANVDTDVSVGLCKSGDNHEAGLSGTDLVNNGVLESQGGACVKERQRVTASTRAPLPAVNGVKVPACAPMFPDVESQDSSESVEPEGQVKVGSTNGKSSSPFLEDSLETDGLDAKAENGNIGGTEQSSEKPTHCQGSSDIAECTGEAMEGSGAHNEEPVGTDTSSSREGGSVDSADRAQEVASCCPPVDQTTVNDEMGDKLKLDGTQGSVQEPRLLPLEDASTFSAGKEPPKAEERAESASGQGMPHPDAGDLAVGRTGDAAVAPPGQEAPLCSNDPVLPPCTKGAECTEDNFVGTPFVIRNEESKQKQEVAAAGSAELAAPHGQERGGVAGVLEDYAGAPGPPKQSLQPRAEGDTAKPEREASDSSQEQVLSENLLVTVVKSFVGSAERPAASSDVGAGLKELGPNQAGTAGAGDSIMQGTGPAAGSNPCPDAGLPQECGPSLQHVSPRSSTPELKDALEMEAPSLAFEAEEALQIAAITSITGYEEEQGEMESVLPRATLQPIAEEPTCDSDSSSDTVGQGGDGDSAPTSTAAQGLVTAQPEGKQSQGISEPTPSPCSSGFNAVESPEHVGVKSSVSADDGSSLDKVPKMVKSFDAVVFAAETPSSPGLPAEGKVGPEPQPAVDVAAGLDGEADLRSSARKDVSQAIRGAKPATGKLEMKTEDEVDFMKDPRESAAREEAINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKQHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSSMRVLGDGIKKPPIHRRSLSWCPSGVQFAAMGPDFNCRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 2672, "header": "tr|A0A8V0ZBV8-1|A0A8V0ZBV8_CHICK Isoform 1 of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14129568, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048608.1", "url": "https://www.ensembl.org/id/ENSGALT00010048608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028699.1", "url": "https://www.ensembl.org/id/ENSGALP00010028699.1" } ] } }, { "isoform_ac": "A0A8V0ZCP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0ZCP7-1", "sequence": { "sequence": "MAAEYEVLKINRESWCSLEPCPDSSLLERKRTGESPECENFLEDGLSSVCASSQGVLKRESGSESDFFSLPGDGMEDLVFGKQHEEEQSAGDVTSSSSSADDTVSLERNSSLGSDTSLPFPPAVSFAQPKDRRSLDGSCTSMVAVEGGEGELAGLGEKEEELDSITDVPAPSSVSRNSIRPLSPFRRHSWGPGKNATNEAEINQRSYSLEGLAGDSGENKKPSANLEAVSLSSKDLPRSTLTSNQCGSLVLLTEELEQGAIRDYDRQIHQAPHPQGFNFCTSSVSSPLTKSMSLMSISKPSLDSTQAFGGPAGSLVQSISEESSSVPSIKSGTKVSRTFSYLRNKMSSSKKSKEKEKDKEKTKEKDKDSKEKEKDKKMLNGHLFTATSVVAQAICYHCMKPFNKDSYYCANCNAIVHKGCKESFASCAKVKMKPQRGMLQAHDTSSLPTVTMRNKGSQPKERPRSAILAPDENTVTSIFNNRRSQQPTALSKSVSIQNIAGVGNDDSLIHTWKFLSQSTDSLHKISRVNESTESLVDEGADMNEGQLMGDLELDSKQLEAESWSQAVDSLFLQQQNKDVVKRQDVIYELMQTEMHHVRTLKIMNDVYSAGMLQELQYDQQVVDKIFPCLENLLHIHSQFFQRILERKKESLADKSEKNFVIKRIGDILVNQFSGENAERMKKTYGKFCGHHNEAVNYFKDLYSKDKRFQAFVKKKMSSSLVRRLGISECILLVTQRITKYPVLLQRILQYTAENEVEHEDLTQSLNLVKDVIAAVNSKVSNYEKKTRLDEIYNRTDNKSIMRMKSGQMFAREDLRHRKLIRDGPVSLKNAAGRLKEVQAVLLSDMLVFLQEKDQKYVFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGVKDPEMVEVHASSKEERNGWIQIIQDTISTMDKDEDEGVPCESEFEKKLSDTRIRALKEQLQQKDRQILLLLEEKAKIFGDMADSSMQEDMPGSRLLFRANTEEAPKGEAIMKTAINEVELLQDLVNRNLGSTLLQQLSSAAIDEEGGVGPISLPKRAETFGGFDSHQMNASKGGTKDEGDDAQDLRRTESDGVLKKAGNANLMFILKRNSEQVLQSVTSLRKLLSALQGVVLQQDTYIEGQKLALSERALSRGFFRPASLLEQEKQRNLEKQRQELANLKKQQAQHQEEKRRAEKECEAREKKLAELEVQLAKREEEIQKGWQELECRREELRQLKASYQVEMEKLLIKQKQLDKEWEQLRKDMERQPQMWLEHDDNQVSNRHEKLARVCSQSSLEGTSKQKSPSFPKKGHSDAELSVSPKRNNLSRTHKEKSTSHLLSTTNQTNKAAEEQPQMPTRLFSLSKPKEKKEKKKKGRGHRSQESDSHSSEAPPEGEEIFC", "length": 1390, "header": "tr|A0A8V0ZCP7-1|A0A8V0ZCP7_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14063094, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048585.1", "url": "https://www.ensembl.org/id/ENSGALT00010048585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028676.1", "url": "https://www.ensembl.org/id/ENSGALP00010028676.1" } ] } }, { "isoform_ac": "A0A8V0ZJA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8/entry#A0A8V0ZJA6-1", "sequence": { "sequence": 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"length": 1403, "header": "tr|A0A8V0ZJA6-1|A0A8V0ZJA6_CHICK Computationally mapped isoform of A-kinase anchoring protein 13 OS=Gallus gallus OX=9031 GN=AKAP13 PE=1 SV=1 CANONICAL=A0A8V0ZBV8-1" }, "locus": { "chromosome": "10", "start_pos": 14072155, "end_pos": 13989554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048593.1", "url": "https://www.ensembl.org/id/ENSGALT00010048593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028683.1", "url": "https://www.ensembl.org/id/ENSGALP00010028683.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": 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"go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV8" } ], 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDI2-1", "uniprot_ac": "A0A8V0ZDI2", "uniprot_id": "A0A8V0ZDI2_CHICK", "mass": { "chemical_mass": 88457.0, "monoisotopic_mass": 88457.0 }, "refseq": { "ac": "XP_015147189", "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147189" }, "gene_names": [ { "name": "NAALADL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2" } ] }, { "name": "NAALADL2", "type": "synonym", "evidence": [ { "id": "XP_015147189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147189" } ] } ], "protein_names": [ { "name": "N-acetylated alpha-linked acidic dipeptidase like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2/entry#names_and_taxonomy" } ] }, { "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015147189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147189" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147189.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147189" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAALADL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2", "locus": { "chromosome": "9", "start_pos": 18013481, "end_pos": 18381753, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018465", "url": "https://www.ensembl.org/id/ENSGALG00010018465" } ] } } ], "crossref": [ { "id": "A0A8V0ZDI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02131", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429156", "url": "https://www.ncbi.nlm.nih.gov/gene/429156", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429156", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429156", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYYAHKK", "url": "https://omabrowser.org/oma/group/GYYAHKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z628", "url": "https://www.orthodb.org/?gene=A0A8V0Z628", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7M2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7M8", "url": "https://www.orthodb.org/?gene=A0A8V0Z7M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z628", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z628", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z628-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z628-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPFLALPYGESVKKMAYHKVNADQRTQGQYLDSDDLQATALELEWDMEKELEEPGFDHFRLDGAVQQDLGNSQSPDLDLEPIQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYRNILYRLDERTSQFSVLLEALEHCKLHQSNETIQATLSEVLNSISSAQVYFKAGLDVFETTLAGKK", "length": 793, "header": "tr|A0A8V0ZDI2-1|A0A8V0ZDI2_CHICK Isoform 1 of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Gallus gallus OX=9031 GN=NAALADL2 PE=1 SV=1 CANONICAL=A0A8V0ZDI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z628-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2/entry#A0A8V0Z628-1", "sequence": { "sequence": "MAYHKVNADQRTQGQYLDSDDLQATALELEWDMEKELEEPGFDHFRLDGAVQQDLGNSQSPDLDLEPIQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYRNILYRLDERTSQFSVLLEALEHCKLHQSNETIQATLSEVLNSISSAQVYFKAGLDVFETTLAGKK", "length": 778, "header": "tr|A0A8V0Z628-1|A0A8V0ZDI2_CHICK Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Gallus gallus OX=9031 GN=NAALADL2 PE=1 SV=1 CANONICAL=A0A8V0ZDI2-1" }, "locus": { "chromosome": "9", "start_pos": 18217929, "end_pos": 18022803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044672.1", "url": "https://www.ensembl.org/id/ENSGALT00010044672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026605.1", "url": "https://www.ensembl.org/id/ENSGALP00010026605.1" } ] } }, { "isoform_ac": "A0A8V0Z7M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2/entry#A0A8V0Z7M2-1", "sequence": { "sequence": "MEENESSLPNASQQVKKMAYHKVNADQRTQGQYLDSDDLQATALELEWDMEKELEEPGFDHFRLDGAVQQDLGNSQSPDLDLEPIQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYSEL", "length": 732, "header": "tr|A0A8V0Z7M2-1|A0A8V0ZDI2_CHICK Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Gallus gallus OX=9031 GN=NAALADL2 PE=1 SV=1 CANONICAL=A0A8V0ZDI2-1" }, "locus": { "chromosome": "9", "start_pos": 18300557, "end_pos": 18014857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044661.1", "url": "https://www.ensembl.org/id/ENSGALT00010044661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026596.1", "url": "https://www.ensembl.org/id/ENSGALP00010026596.1" } ] } }, { "isoform_ac": "A0A8V0Z7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2/entry#A0A8V0Z7M8-1", "sequence": { "sequence": "MAYHKVNADQRTQGQYLDSDDLQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYRNILYRLDERTSQFSVLLEALEHCKLHQSNETIQATLSEVLNSISSAQVYFKAGLDVFETTLAGKK", "length": 732, "header": "tr|A0A8V0Z7M8-1|A0A8V0ZDI2_CHICK Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Gallus gallus OX=9031 GN=NAALADL2 PE=1 SV=1 CANONICAL=A0A8V0ZDI2-1" }, "locus": { "chromosome": "9", "start_pos": 18217929, "end_pos": 18022803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044668.1", "url": "https://www.ensembl.org/id/ENSGALT00010044668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026601.1", "url": "https://www.ensembl.org/id/ENSGALP00010026601.1" } ] } }, { "isoform_ac": "A0A8V0ZDI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2/entry#A0A8V0ZDI2-1", "sequence": { "sequence": "MCPFLALPYGESVKKMAYHKVNADQRTQGQYLDSDDLQATALELEWDMEKELEEPGFDHFRLDGAVQQDLGNSQSPDLDLEPIQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYRNILYRLDERTSQFSVLLEALEHCKLHQSNETIQATLSEVLNSISSAQVYFKAGLDVFETTLAGKK", "length": 793, "header": "tr|A0A8V0ZDI2-1|A0A8V0ZDI2_CHICK Isoform 1 of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Gallus gallus OX=9031 GN=NAALADL2 PE=1 SV=1 CANONICAL=A0A8V0ZDI2-1" }, "locus": { "chromosome": "9", "start_pos": 18263340, "end_pos": 18022803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044658.1", "url": "https://www.ensembl.org/id/ENSGALT00010044658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026594.1", "url": "https://www.ensembl.org/id/ENSGALP00010026594.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 352, "start_aa": "Thr", "end_pos": 352, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr352", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429156", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429156", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0N4SUJ3-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase-like 2", "gene_name": "Naaladl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGENEAGLPNMSLQGKKMAYQKVKADLRTSGHSQYLDNDELQATALDLEWDMEKELEEPGFDQFQPDSAEHQNLGHSETLDLHLDSIQPATSPKGRFQRLQEESDCVTHYTRSAPKNNHCSFCYMLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNWLQLYDSKDDMEIAKKIKSHWIALGLEDTQFINYSVLLDFPGSSPGTITLSSTGQCFYPDGQPCREEARGGHSQDLFFSYAAYSAKGTLQGDVIDVSYGTMDDLKRITKLKNTTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAAESSVLSSEPFVVTLNPGGDPSTPGYPSHDGSFRKSRTNLTSLLVQPISPSLVKMLISLPKLKMDKDACSPLELPHNEKRTVSLQVQTVTQFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGYSYKGQEWASSTAVITAFIEAMMLRVKKGWRPERTIVFCSWGGTPWGKIGSYEWGEDFVKILQKNAVAYIGLHSPIRGNSSLYPVVSPSLQQLVIEKIKFTCMQRAQCLGANVSSVQIQGDADYFINHLGVPTVQFAYEDIKTLEGPSFLSEAIFPTHATKIEEVDPSFSLHEAITKLSGEVILQIANEPILPFNALDIALGVQNSLKGNEPSVPHLLALASRLRESAELFQSDEMRPANDPKERAPSRVRMLNDILQDLEKNFLVQWVPPGFYRNILYHLDEKTNQFSILKEAWEHCNPQTSNETFQEALSNVLNSINSAHISFKVGLDVFESVLLGKN", "length": 795 }, "evidence": [ { "id": "A0A8V0ZDI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A480QLP9-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase like 2", "gene_name": "NAALADL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLDSAENQNLEHAETADLNLDSIQPATSPKGRFQRLQEESDYITHYARSAPKSNPCNFCRLLKIFCTAIILFIFGILIGYYAHKNCPSNATSSGTLDLQLYQEILKTIQAEDIKKSFRNLIQLYKSEDDMEISKKIKIQWTSLGLEDVQFVNYSVLLNLPGPAPSSVTLSSSGQCFHPDGQPCSEEARKHSSQDLLYSYAAYSAKGTLKAEVIDVSYGNADDLKRIKKMKNVTNRIALLKLGRLPLLYKLSLLEKAGFGGVLLYIDPCDLPKTTNLSYDTFMVSLNPGGDPSTPGYPSIDGSFRQNRSNLTSLLVQPVSASLIAKLISSPKATTTNNACTPLELPNNEERIVNMQIQTVTKFKTVTNVVGYLKGLTSPDRYILVGSRHHTAYSYNGQEWASSTAIITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQRNVVAYVSLHSPIRGNSSLYSVASPSLQQLVAEKNNFNCSRRGQCPETNVSSVQMQDDADYFINHLGIPTVRFSYEDSQLSEGPSFLFEALFPKHTTKIEELDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQPNTPQLLAPASRLRESTELFQSDEMRPANDPKERAPIRVRMLNDILQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESILVGKN", "length": 795 }, "evidence": [ { "id": "A0A8V0ZDI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6ACN8-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase-like 2", "gene_name": "Naaladl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGENEAGLPNMALQGKKMAYHKVKADLRTSGHSQYLDSDDLQATALDLEWDMEKELEEPSFDQFQTDNAEHQNLGHSETLDLHLDSIQPATSPKGRFQRLQEESDCVTHYTRSAPKNNHCNFCYLLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNLLQVYDSEDDMEISKKIKSHWIALGLEDTQFINYSVLLDCPGPSPGTITVSSTGQCFYPDGQPCREEARRGQSQDLFYSYAAYSAKGTLQADVIDVSYGTMDDLKRITKLKNTTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAPESAVLSSEPFMVTLNPGGDPSTPGYPSHDESFRQSRPNLTSLLVQPISASLATVLISSPKLRMDKDVCRPLELPHNEKRTVSLQVQTVTKFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGHSYNGQEWASSTAVITAFIEALMLRVKKGWRPERTVVFCSWGGTPWGKIGSYEWGEDFAKILQKNAVAYVSIHSPIRGNSTLYPVASPSLQQLVLEKNKFNCVRRAQCPGANVSSVQIQGDAEYFVNHLGVPTVQFAYEDIKALEGPSFLSEAIFPKHATKIEELDPSFNLHEVITKLSGEVILQIANDPVLPFNALDIALGVQNSLKDNEPSVPNLLALASKLRDSAELFQSDEMRPANDPKERVPSRVRMLNDILQDLEKNFLVQRVPPGFYRNILYHLDEKTSQFSILKEAWEQCIPETSNETLQEALSTVLNSINSAHTFFKTGLDVFESVLLEKN", "length": 795 }, "evidence": [ { "id": "A0A8V0ZDI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TUG4-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase like 2", "gene_name": "NAALADL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 795 }, "evidence": [ { "id": "A0A8V0ZDI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q58DX5-1", "protein_name": "Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2", "gene_name": "NAALADL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFLVKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYFKAGLDVFKSVLDGKN", "length": 795 }, "evidence": [ { "id": "A0A8V0ZDI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI2" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 426, "end_pos": 590, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 352 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 757, "end_pos": 759 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDF7-1", "uniprot_ac": "A0A8V0ZDF7", "uniprot_id": "A0A8V0ZDF7_CHICK", "mass": { "chemical_mass": 34940.0, "monoisotopic_mass": 34940.0 }, "refseq": { "ac": "XP_015149783", "name": "protein N-terminal asparagine amidohydrolase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149783" }, "gene_names": [ { "name": "NTAN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ] }, { "name": "NTAN1", "type": "synonym", "evidence": [ { "id": "XP_015149783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149783" } ] } ], "protein_names": [ { "name": "N-terminal asparagine amidase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7/entry#names_and_taxonomy" } ] }, { "name": "protein N-terminal asparagine amidohydrolase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149783" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149783.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149783" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NTAN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7", "locus": { "chromosome": "14", "start_pos": 82284, "end_pos": 90928, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020137", "url": "https://www.ensembl.org/id/ENSGALG00010020137" } ] } } ], "crossref": [ { "id": "A0A8V0ZDF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "768445", "url": "https://www.ncbi.nlm.nih.gov/gene/768445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRETFPM", "url": "https://omabrowser.org/oma/group/WRETFPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z666", "url": "https://www.orthodb.org/?gene=A0A8V0Z666", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDF7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12498", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12498", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12498:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12498:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149783", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z666", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z666", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z666-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z666-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLLINGERIDLTRLTGGVIRAHPHLEEKAKLLRSQPTQIVEPKGLLYVQQREFAVTTPNDGSVSILGSDDATTCHLIVLRHTGSGATCLTHCDGSDTEAEVSLIMSSVKSFSNTTGYGRLEVHLVGGFNDDRQLSQKLTNQLLRAFDLQPDDVHLVTFCVTELNDREEKDIHFPIIYGIAVNVKTAEIFPATFPEKGPDEDLRSAHVLTGARLTNIYDAKTEQLHIGPYFWRPFPHVDFWLDQDDQQILQNLSTSPLAEPPHFVSHIRSTLTFLKEHPFPSHSLFPDRKPRIYKKNEEGLWELVCSDKI", "length": 310, "header": "tr|A0A8V0ZDF7-1|A0A8V0ZDF7_CHICK Isoform 1 of N-terminal asparagine amidase OS=Gallus gallus OX=9031 GN=NTAN1 PE=4 SV=1 CANONICAL=A0A8V0ZDF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z666-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7/entry#A0A8V0Z666-1", "sequence": { "sequence": "MPLLINGERIDLTRLTGGVIRAHPHLEEKAKLLRSQPTQIVEPKGLLYVQQREFAVTTPNDGSVSILGSDDATTCHLIVLRHTGSGATCLTHCDGSDTEAEVSLIMSSVKSFSNTTGYGRLEVHLVGGFNDDRQLSQKLTNQLLRAFDLQPDDVHLVTFCVTELNDREEKDIHFPIIYGIAVNVKTAEIFPATFPEKGPDEDLRSAHVLTGARNLSTSPLAEPPHFVSHIRSTLTFLKEHPFPSHSLFPDRKPRIYKKNEEGLWELVCSDKI", "length": 272, "header": "tr|A0A8V0Z666-1|A0A8V0ZDF7_CHICK Computationally mapped isoform of N-terminal asparagine amidase OS=Gallus gallus OX=9031 GN=NTAN1 PE=4 SV=1 CANONICAL=A0A8V0ZDF7-1" }, "locus": { "chromosome": "14", "start_pos": 89956, "end_pos": 82733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048651.1", "url": "https://www.ensembl.org/id/ENSGALT00010048651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028742.1", "url": "https://www.ensembl.org/id/ENSGALP00010028742.1" } ] } }, { "isoform_ac": "A0A8V0ZDF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7/entry#A0A8V0ZDF7-1", "sequence": { "sequence": "MPLLINGERIDLTRLTGGVIRAHPHLEEKAKLLRSQPTQIVEPKGLLYVQQREFAVTTPNDGSVSILGSDDATTCHLIVLRHTGSGATCLTHCDGSDTEAEVSLIMSSVKSFSNTTGYGRLEVHLVGGFNDDRQLSQKLTNQLLRAFDLQPDDVHLVTFCVTELNDREEKDIHFPIIYGIAVNVKTAEIFPATFPEKGPDEDLRSAHVLTGARLTNIYDAKTEQLHIGPYFWRPFPHVDFWLDQDDQQILQNLSTSPLAEPPHFVSHIRSTLTFLKEHPFPSHSLFPDRKPRIYKKNEEGLWELVCSDKI", "length": 310, "header": "tr|A0A8V0ZDF7-1|A0A8V0ZDF7_CHICK Isoform 1 of N-terminal asparagine amidase OS=Gallus gallus OX=9031 GN=NTAN1 PE=4 SV=1 CANONICAL=A0A8V0ZDF7-1" }, "locus": { "chromosome": "14", "start_pos": 89956, "end_pos": 82733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048649.1", "url": "https://www.ensembl.org/id/ENSGALT00010048649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028740.1", "url": "https://www.ensembl.org/id/ENSGALP00010028740.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768445", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NBY0-1", "protein_name": "N-terminal asparagine amidase", "gene_name": "NTAN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLLVDGRRVRLPQSAGDLVRAHPLLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSVSILGSDDATTCHIVVLRHTGNGATCLTHCDGSDTKAEVPLIMNAIKSFPDHTQCGRLEAHLVGGFNDDRQLSQKLTHQLLSEFDRQEDDIHLVTLCVTELNDREENESHFPIIYGIAVNIKTAEIYRASFQDRGPEEELRAARALTGGPMISIYDAKTEQLRIGPYSWTPFPHVDFWLQQDDKQILENLSTSPLAEPPHFVEHIRSTLMFLKKHPSPANTLFPGNKALLYKKNEDGLWEKISSPGS", "length": 310 }, "evidence": [ { "id": "A0A8V0ZDF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q28955-1", "protein_name": "Protein N-terminal asparagine amidohydrolase", "gene_name": "NTAN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLLVEGRRVRLPQSAGDLVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSVCILGSDDATTCHIVVLRHTGNGATCLTHCDGTDTKAEVSLIMSSIKSFSDHTQRGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDRQEDDIHLVTLCVTELNDREENENHFPIIYGIAVNVKTAEIYRASFPDRGPEEELRAARVLTGGPMISIYDAKTEQLRIGPYSWMPFPHVDFWLQQDDKQILENLSTSPLAEPPHFVEHIRSTLMFLKKYPSPTNTLFPGNKALLYKKNEDGLWKEISSGGET", "length": 311 }, "evidence": [ { "id": "A0A8V0ZDF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q64311-1", "protein_name": "Protein N-terminal asparagine amidohydrolase", "gene_name": "Ntan1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLLVDGQRVRLPRSAVELVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSISILGSDDATTCHIVVLRHTGNGATCLTHCDGSDTKAEVPLIMSSIKSFSEHAECGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDKQDDDIHLVTLCVTELNDREENENHFPIIYGIAVNIKTAEIYRASFQDRGPEEQLRAARALAGGPMISIYDAKTEQLRIGPCSWTPFPQVDFWLQQDDKQILESLSTSPLAEPPHFVEHIRSTLMFLKKFPSPENILFPGNKALLYKKNKDGLWEKISSPGS", "length": 310 }, "evidence": [ { "id": "A0A8V0ZDF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AB6-1", "protein_name": "Protein N-terminal asparagine amidohydrolase", "gene_name": "NTAN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLVEGRRVRLPQSAGDLVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQRELAVTSPKDGSISILGSDDATTCHIVVLRHTGNGATCLTHCDGTDTKAEVPLIMNSIKSFSDHAQCGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDRQEDDIHLVTLCVTELNDREENENHFPVIYGIAVNIKTAEIYRASFQDRGPEEQLRAARTLAGGPMISIYDAETEQLRIGPYSWTPFPHVDFWLHQDDKQILENLSTSPLAEPPHFVEHIRSTLMFLKKHPSPAHTLFSGNKALLYKKNEDGLWEKISSPGS", "length": 310 }, "evidence": [ { "id": "A0A8V0ZDF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-N-terminal asparagine amidohydrolase activity", "id": "GO:0008418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC12-1", "uniprot_ac": "A0A8V0ZC12", "uniprot_id": "A0A8V0ZC12_CHICK", "mass": { "chemical_mass": 121509.0, "monoisotopic_mass": 121509.0 }, "refseq": { "ac": "XP_046754993", "name": "selenocysteine insertion sequence-binding protein 2-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754993" }, "gene_names": [ { "name": "SECISBP2L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ] }, { "name": "SECISBP2L", "type": "synonym", "evidence": [ { "id": "XP_046754993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754993" } ] } ], "protein_names": [ { "name": "SECIS binding protein 2 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12/entry#names_and_taxonomy" } ] }, { "name": "selenocysteine insertion sequence-binding protein 2-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046754993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754993" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754993" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SECISBP2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12", "locus": { "chromosome": "10", "start_pos": 10426950, "end_pos": 10449556, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020140", "url": "https://www.ensembl.org/id/ENSGALG00010020140" } ] } } ], "crossref": [ { "id": "A0A8V0ZC12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC12", "database": "AlphaFoldDB", "categories": [] }, { "id": "415435", "url": "https://www.ncbi.nlm.nih.gov/gene/415435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z677", "url": "https://www.orthodb.org/?gene=A0A8V0Z677", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC12", "url": "https://www.orthodb.org/?gene=A0A8V0ZC12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13284", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13284", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13284:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13284:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046754993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z677", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z677", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z677-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z677-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKADKNVKLSAEVEPFIPQKKGPETLMIPMALPNDSGGINGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPPPYSAPFQTANAVNTVTTECTERPNPPGQVFPLSTQRSRSSNRGPIIPKQQQLQMHIKNKRPPVKNVATQKETSSSGPENRSKIVLLVDASQQTDFPSDIANKSLSESASTMLWKSKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHGNNQAAAVTSRNADSCAMNVVEPSINATGTFLSAGVSWTNVNSQATQKKPWIEKTQTFIRGGRQAEQRNSSQSGFRCRGHSTSSERRQNLQKRHEKPLTTSQSSRAEQSPEPLYFEDEDEFPELNSDNGNSKSSNIQQKISPKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKSKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVGSAAPFHTKESANRKSLTKGQPSMGCLNPLDSTAPKVKRGKEREISKLKRPTALKKIILKEREEKKGRLSVDHSLLGSDEQKQVHISLPTDQSQELASQEETGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSAITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPMRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAEDLFNKLVSLTEEARKAYRDMVAAMEQEQAEEALKNVKKAPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENERESSSQTAVPEKAGNGQIAKSTLHKQPPLAATSTTSATNHGKATPGEKEEVKPDDNLEWASQQSTETGSLDGSCRDILNSSMISTTSTLVPGMLEEEDEEDEEDDEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLSGAEEDNAEQSEEEEIETSEQVDPAVDSEEWTNDKHASNIQHKPTICGSLNKEHTDSIYMP", "length": 1102, "header": "tr|A0A8V0ZC12-1|A0A8V0ZC12_CHICK Isoform 1 of SECIS binding protein 2 like OS=Gallus gallus OX=9031 GN=SECISBP2L PE=1 SV=1 CANONICAL=A0A8V0ZC12-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z677-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12/entry#A0A8V0Z677-1", "sequence": { "sequence": "MSGHAENVKLSAEVEPFIPQKKGPETLMIPMALPNDSGGINGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPPPYSAPFQTANAVNTVTTECTERPNPPGQVFPLSTQRSRSSNRGPIIPKQQQLQMHIKNKRPPVKNVATQKETSSSGPENRSKIVLLVDASQQTDFPSDIANKSLSESASTMLWKSKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHGNNQAAAVTSRNADSCAMNVVEPSINATGVSWTNVNSQATQKKPWIEKTQTFIRGGRQAEQRNSSQSGFRCRGHSTSSERRQNLQKRHEKPLTTSQSSRAEQSPEPLYFEDEDEFPELNSDNGNSKSSNIQQKISPKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKSKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVGSAAPFHTKESANRKSLTKGQPSMGCLNPLDSTAPKVKRGKEREISKLKRPTALKKIILKEREEKKGRLSVDHSLLGSDEQKQVHISLPTDQSQELASQEETGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSAITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPMRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAEDLFNKLVSLTEEARKAYRDMVAAMEQEQAEEALKNVKKAPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENERESSSQTAVPEKAGNGQIAKSTLHKQPPLAATSTTSATNHGKATPGEKEEVKPDDNLEWASQQSTETGSLDGSCRDILNSSMISTTSTLVPGMLEEEDEEDEEDDEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLSGAEEDNAEQSEEEEIETSEQVDPAVDSEEWTNDKHASNIQHKPTICGSLNKEHTDSIYMP", "length": 1096, "header": "tr|A0A8V0Z677-1|A0A8V0ZC12_CHICK Computationally mapped isoform of SECIS binding protein 2 like OS=Gallus gallus OX=9031 GN=SECISBP2L PE=1 SV=1 CANONICAL=A0A8V0ZC12-1" }, "locus": { "chromosome": "10", "start_pos": 10449534, "end_pos": 10427554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048661.1", "url": "https://www.ensembl.org/id/ENSGALT00010048661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028752.1", "url": "https://www.ensembl.org/id/ENSGALP00010028752.1" } ] } }, { "isoform_ac": "A0A8V0ZC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12/entry#A0A8V0ZC12-1", "sequence": { "sequence": "MDKADKNVKLSAEVEPFIPQKKGPETLMIPMALPNDSGGINGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPPPYSAPFQTANAVNTVTTECTERPNPPGQVFPLSTQRSRSSNRGPIIPKQQQLQMHIKNKRPPVKNVATQKETSSSGPENRSKIVLLVDASQQTDFPSDIANKSLSESASTMLWKSKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHGNNQAAAVTSRNADSCAMNVVEPSINATGTFLSAGVSWTNVNSQATQKKPWIEKTQTFIRGGRQAEQRNSSQSGFRCRGHSTSSERRQNLQKRHEKPLTTSQSSRAEQSPEPLYFEDEDEFPELNSDNGNSKSSNIQQKISPKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKSKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVGSAAPFHTKESANRKSLTKGQPSMGCLNPLDSTAPKVKRGKEREISKLKRPTALKKIILKEREEKKGRLSVDHSLLGSDEQKQVHISLPTDQSQELASQEETGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSAITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPMRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYSGAEDLFNKLVSLTEEARKAYRDMVAAMEQEQAEEALKNVKKAPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENERESSSQTAVPEKAGNGQIAKSTLHKQPPLAATSTTSATNHGKATPGEKEEVKPDDNLEWASQQSTETGSLDGSCRDILNSSMISTTSTLVPGMLEEEDEEDEEDDEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLSGAEEDNAEQSEEEEIETSEQVDPAVDSEEWTNDKHASNIQHKPTICGSLNKEHTDSIYMP", "length": 1102, "header": "tr|A0A8V0ZC12-1|A0A8V0ZC12_CHICK Isoform 1 of SECIS binding protein 2 like OS=Gallus gallus OX=9031 GN=SECISBP2L PE=1 SV=1 CANONICAL=A0A8V0ZC12-1" }, "locus": { "chromosome": "10", "start_pos": 10449089, "end_pos": 10427554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048658.1", "url": "https://www.ensembl.org/id/ENSGALT00010048658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028749.1", "url": "https://www.ensembl.org/id/ENSGALP00010028749.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "selenocysteine incorporation", "id": "GO:0001514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "selenocysteine insertion sequence binding", "id": "GO:0035368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 977, "end_pos": 979, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC12" }, { "id": "PF01248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal protein eL8/eL30/eS12/Gadd45", "eco_id": "ECO_0000259", "start_pos": 710, "end_pos": 807, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 800, "end_pos": 802 }, { "start_pos": 977, "end_pos": 979 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD57-1", "uniprot_ac": "A0A8V0ZD57", "uniprot_id": "A0A8V0ZD57_CHICK", "mass": { "chemical_mass": 84068.0, "monoisotopic_mass": 84068.0 }, "refseq": {}, "gene_names": [ { "name": "LRFN5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z697", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z697#function" }, { "database": "UniProtKB", "id": "ARBA00037389", "url": "https://www.uniprot.org/uniprotkb/ARBA00037389#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRFN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57", "locus": { "chromosome": "5", "start_pos": 59247832, "end_pos": 59267042, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018398", "url": "https://www.ensembl.org/id/ENSGALG00010018398" } ] } } ], "crossref": [ { "id": "A0A8V0ZD57", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD57", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z697", "url": "https://www.orthodb.org/?gene=A0A8V0Z697", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD57", "url": "https://www.orthodb.org/?gene=A0A8V0ZD57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z697", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z697", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z697-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z697-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLLLFLLFIGIAVRAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVLALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDHIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPQLLSGRYFWSIPEEEFLCEPPLITRHTHELRVLEGQRAALRCKARGDPEPAIHWISPEGKLISNATRSVVYDNGTLDILITTVKDTGSFTCIASNPAGEATQTVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNASSSNGDTKVSQDKKVVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDSLVMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCTQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKATKVSNVYSQTNGAQVQACGGALSQSASKQAVGHEEAAQCCRAASDGAGPSPEPSPGPEATAATTTSPSPHAWAAGTSATQKPKRKPGPKPSSEPQSEAAMSIESQNTNRNNSTALQLASRPPDSDKGVPTYKRAQSKPSKFLTLPATTSRAKRRLSLGGELLLCRCQQDVGLCSRRSLSMNGMLAQVGRSGAEGGTATFSSSEWILESTV", "length": 772, "header": "tr|A0A8V0ZD57-1|A0A8V0ZD57_CHICK Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 5 OS=Gallus gallus OX=9031 GN=LRFN5 PE=3 SV=1 CANONICAL=A0A8V0ZD57-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z697-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57/entry#A0A8V0Z697-1", "sequence": { "sequence": "MEKLLLFLLFIGIAVRAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVLALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDHIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPQLLSGRYFWSIPEEEFLCEPPLITRHTHELRVLEGQRAALRCKARGDPEPAIHWISPEGKLISNATRSVVYDNGTLDILITTVKDTGSFTCIASNPAGEATQTVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNASSSNGDTKVSQDKKVVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDSLVYRMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCTQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKATKVSNVYSQTNGAQVQACGGALSQSASKQAVGHEEAAQCCRAASDGAGPSPEPSPGPEATAATTTSPSPHAWAAGTSATQKPKRKPGPKPSSEPQSEAAMSIESQNTNRNNSTALQLASRPPDSDKGVPTYKRAQSKPTGADLKDTHTAPLLESSCPNLATRQKTKRSQRTKD", "length": 737, "header": "tr|A0A8V0Z697-1|A0A8V0ZD57_CHICK Computationally mapped isoform of Leucine-rich repeat and fibronectin type-III domain-containing protein 5 OS=Gallus gallus OX=9031 GN=LRFN5 PE=3 SV=1 CANONICAL=A0A8V0ZD57-1" }, "locus": { "chromosome": "5", "start_pos": 59257260, "end_pos": 59248129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044439.1", "url": "https://www.ensembl.org/id/ENSGALT00010044439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026450.1", "url": "https://www.ensembl.org/id/ENSGALP00010026450.1" } ] } }, { "isoform_ac": "A0A8V0ZD57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57/entry#A0A8V0ZD57-1", "sequence": { "sequence": "MEKLLLFLLFIGIAVRAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVLALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDHIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPQLLSGRYFWSIPEEEFLCEPPLITRHTHELRVLEGQRAALRCKARGDPEPAIHWISPEGKLISNATRSVVYDNGTLDILITTVKDTGSFTCIASNPAGEATQTVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNASSSNGDTKVSQDKKVVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDSLVMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCTQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKATKVSNVYSQTNGAQVQACGGALSQSASKQAVGHEEAAQCCRAASDGAGPSPEPSPGPEATAATTTSPSPHAWAAGTSATQKPKRKPGPKPSSEPQSEAAMSIESQNTNRNNSTALQLASRPPDSDKGVPTYKRAQSKPSKFLTLPATTSRAKRRLSLGGELLLCRCQQDVGLCSRRSLSMNGMLAQVGRSGAEGGTATFSSSEWILESTV", "length": 772, "header": "tr|A0A8V0ZD57-1|A0A8V0ZD57_CHICK Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 5 OS=Gallus gallus OX=9031 GN=LRFN5 PE=3 SV=1 CANONICAL=A0A8V0ZD57-1" }, "locus": { "chromosome": "5", "start_pos": 59257260, "end_pos": 59254341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044434.1", "url": "https://www.ensembl.org/id/ENSGALT00010044434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026447.1", "url": "https://www.ensembl.org/id/ENSGALP00010026447.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD57" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD57", "url": 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"https://www.ensembl.org/id/ENSGALP00010026661.1" } ] } }, { "isoform_ac": "A0A8V0ZDN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN8/entry#A0A8V0ZDN8-1", "sequence": { "sequence": "MYQPAFIPNPCTLSYMLMEVQVEPIRLLCLMFYRGWLWSFSSVEPVDHGDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSGMLGYLSVCFFTILMEGTQ", "length": 154, "header": "tr|A0A8V0ZDN8-1|A0A8V0ZDN8_CHICK Isoform 1 of CEP152 CEP63 binding coiled coil domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDN8-1" }, "locus": { "chromosome": "10", "start_pos": 10362307, "end_pos": 10361413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044737.1", "url": "https://www.ensembl.org/id/ENSGALT00010044737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026659.1", "url": "https://www.ensembl.org/id/ENSGALP00010026659.1" } ] } }, { "isoform_ac": "A0A8V0ZDP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN8/entry#A0A8V0ZDP2-1", "sequence": { "sequence": "MTCVPVGDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSGR", "length": 95, "header": "tr|A0A8V0ZDP2-1|A0A8V0ZDP2_CHICK Computationally mapped isoform of CEP152 CEP63 binding coiled coil domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDN8-1" }, "locus": { "chromosome": "10", "start_pos": 10362036, "end_pos": 10352211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044742.1", "url": "https://www.ensembl.org/id/ENSGALT00010044742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026664.1", "url": "https://www.ensembl.org/id/ENSGALP00010026664.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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{ "uniprot_canonical_ac": "A0A8V0ZD40-1", "uniprot_ac": "A0A8V0ZD40", "uniprot_id": "A0A8V0ZD40_CHICK", "mass": { "chemical_mass": 90759.0, "monoisotopic_mass": 90759.0 }, "refseq": {}, "gene_names": [ { "name": "CDC2L1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ], "protein_names": [ { "name": "Galactosyltransferase-associated protein kinase p58/GTA", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.23", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC2L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40", "locus": { "chromosome": "21", "start_pos": 2022005, "end_pos": 2008666, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020163", "url": "https://www.ensembl.org/id/ENSGALG00010020163" } ] } } ], "crossref": [ { "id": "A0A8V0ZD40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07843", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07843", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6A9", "url": "https://www.orthodb.org/?gene=A0A8V0Z6A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC38", "url": "https://www.orthodb.org/?gene=A0A8V0ZC38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD40", "url": "https://www.orthodb.org/?gene=A0A8V0ZD40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10216", "url": "https://www.rhea-db.org/rhea/10216", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFGTPMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRMKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKTHHRKDEKRKEKRRHRSHSAEGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERERERKIREQQKEQREQKERERRAEERRKEREARREVSAHHRTVREEYGDKVKMRPWSRSPLRQQRDKPEQADSRKPVKEEKPEERDPLSDLQDISDSERKTSSAESSSAESGSGSEEEEEESSSEGSEEEGEEEEEEEEEETGSNSEEVSEQSAEEVSEEEMSEEEERENGNHIPVVTESRFDRDSAGSEVEEEEVGEGSPQSNAMTEGDYVPDSPASSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHLNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHSGILKVGDFGLAREYGSPLKPYTPVVVTLWYRAPELLLGAKEYSTAIDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNELPAVKKMTFTEYPYNNLRKRFGALLSDQGFDLMNNFLTYYPARRITAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKDTGFHLTTTNQGASAAGPGFSLKF", "length": 778, "header": "tr|A0A8V0ZD40-1|A0A8V0ZD40_CHICK Isoform 1 of Galactosyltransferase-associated protein kinase p58/GTA OS=Gallus gallus OX=9031 GN=CDC2L1 PE=1 SV=1 CANONICAL=A0A8V0ZD40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#A0A8V0Z6A9-1", "sequence": { "sequence": "MVFGTPMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRMKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKTHHRKDEKRKEKRRHRSHSAEGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERERERKIREQQKEQREQKERERRAEERRKEREARREVKEEKPEERDPLSDLQDISDSERKTSSAESSSAESGSGSEEEEEESSSEGSEEEGEEEEEEEEEETGSNSEEVSEQSAEEVSEEEMSEEEERENGNHIPVVTESRFDRDSAGSEVEEEEVGEGSPQSNAMTEGDYVPDSPASSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHLNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHSGILKVGDFGLAREYGSPLKPYTPVVVTLWYRAPELLLGAKEYSTAIDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNELPAVKKMTFTEYPYNNLRKRFGALLSDQGFDLMNNFLTYYPARRITAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKDTGFHLTTTNQGASAAGPGFSLKF", "length": 737, "header": "tr|A0A8V0Z6A9-1|A0A8V0ZD40_CHICK Computationally mapped isoform of Galactosyltransferase-associated protein kinase p58/GTA OS=Gallus gallus OX=9031 GN=CDC2L1 PE=1 SV=1 CANONICAL=A0A8V0ZD40-1" }, "locus": { "chromosome": "21", "start_pos": 2021150, "end_pos": 2009014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048707.1", "url": "https://www.ensembl.org/id/ENSGALT00010048707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028782.1", "url": "https://www.ensembl.org/id/ENSGALP00010028782.1" } ] } }, { "isoform_ac": "A0A8V0ZC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#A0A8V0ZC38-1", "sequence": { "sequence": "MVFGTPMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRMKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKTHHRKDEKRKEKRRHRSHSAEGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERERERKIREQQKEQREQKERERRAEERRKEREARREVSAHHRTVREEYGDKVKMRPWSRSPLRQQRDKPEQADSRKPVKEEKPEERDPLSDLQDISDSERKTSSAESSSAESGSGSEEEEEESSSEGSEEEGEEEEEEEEEETGSNSEEVSEQSAV", "length": 333, "header": "tr|A0A8V0ZC38-1|A0A8V0ZC38_CHICK Computationally mapped isoform of Cell division cycle 2-like 1 (PITSLRE proteins) OS=Gallus gallus OX=9031 GN=CDC2L1 PE=4 SV=1 CANONICAL=A0A8V0ZD40-1" }, "locus": { "chromosome": "21", "start_pos": 2013605, "end_pos": 2009014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048697.1", "url": "https://www.ensembl.org/id/ENSGALT00010048697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028774.1", "url": "https://www.ensembl.org/id/ENSGALP00010028774.1" } ] } }, { "isoform_ac": "A0A8V0ZD40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40/entry#A0A8V0ZD40-1", "sequence": { "sequence": "MVFGTPMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRMKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKTHHRKDEKRKEKRRHRSHSAEGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERERERKIREQQKEQREQKERERRAEERRKEREARREVSAHHRTVREEYGDKVKMRPWSRSPLRQQRDKPEQADSRKPVKEEKPEERDPLSDLQDISDSERKTSSAESSSAESGSGSEEEEEESSSEGSEEEGEEEEEEEEEETGSNSEEVSEQSAEEVSEEEMSEEEERENGNHIPVVTESRFDRDSAGSEVEEEEVGEGSPQSNAMTEGDYVPDSPASSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHLNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHSGILKVGDFGLAREYGSPLKPYTPVVVTLWYRAPELLLGAKEYSTAIDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNELPAVKKMTFTEYPYNNLRKRFGALLSDQGFDLMNNFLTYYPARRITAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKDTGFHLTTTNQGASAAGPGFSLKF", "length": 778, "header": "tr|A0A8V0ZD40-1|A0A8V0ZD40_CHICK Isoform 1 of Galactosyltransferase-associated protein kinase p58/GTA OS=Gallus gallus OX=9031 GN=CDC2L1 PE=1 SV=1 CANONICAL=A0A8V0ZD40-1" }, "locus": { "chromosome": "21", "start_pos": 2021150, "end_pos": 2009014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048716.1", "url": "https://www.ensembl.org/id/ENSGALT00010048716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028791.1", "url": "https://www.ensembl.org/id/ENSGALP00010028791.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10216", "name": "", "equation": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNJ2-1", "A0A8V0Y2I5-1", "Q5ZKN1-1", "A0A8V0YIV6-1", "P13863-1", "E1BUG0-1", "A0A8V0ZD40-1" ], "evidence": [ { "id": "10216", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10216" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-380311", "name": "Recruitment of Plk1 to centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZD40-1" ], "evidence": [ { "id": "R-GGA-380311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380311" } ] }, { "id": "R-GGA-380455", "name": "Recruitment of CDK11p58 to the centrosomes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJI7", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": 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"id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": 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} ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFH3", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", 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] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", 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"evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q9I9E0", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] } ] }, { "uniprot_ac": "Q9IA88", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 706, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.22", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22" }, { "id": "2.7.11.22", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.22" } ] }, { "ec_number": "2.7.11.23", "ec_name": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "2.7.11.23", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23" }, { "id": "2.7.11.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.23" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD19-1", "uniprot_ac": "A0A8V0ZD19", "uniprot_id": "A0A8V0ZD19_CHICK", "mass": { "chemical_mass": 78570.0, "monoisotopic_mass": 78570.0 }, "refseq": {}, "gene_names": [ { "name": "SYT7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ] } ], "protein_names": [ { "name": "Synaptotagmin-7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#names_and_taxonomy" } ] }, { "name": "Synaptotagmin VII", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19", "locus": { "chromosome": "5", "start_pos": 310477, "end_pos": 329571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020160", "url": "https://www.ensembl.org/id/ENSGALG00010020160" } ] } } ], "crossref": [ { "id": "A0A8V0ZD19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD19", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08386", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08386", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748423", "url": "https://www.ncbi.nlm.nih.gov/gene/101748423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748423", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6D0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6D6", "url": "https://www.orthodb.org/?gene=A0A8V0Z6D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD19", "url": "https://www.orthodb.org/?gene=A0A8V0ZD19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD30", "url": "https://www.orthodb.org/?gene=A0A8V0ZD30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDL2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDM6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFSAAAPCHAPAALHVGSTRRRTLFPIHEIHGHLKGAQQQCASPSVPTQRDPSALPAAACLLCSARARLHPRGRVVHRAIPARCGAPGTVVPRVLCWEGWGNGDGAGWLRHVSGRRVAPRDPPSHSSSLITQLADEVGRALRSHRAGGGGEMAPRERREAVPRPGGRETAGCSLWPLPERSLHWGIFSLTLFFSFLQFCPFTFFSFLSSPLPFLSLSFEDSTLSTATTLEYIPTSAGDPKCQRPRTLMRQQSLQQPLSQHQRSNHSQPTTSQSLGHLQAHSSSSGGAGNPRGSRGGQARQGIAAGSKQRTSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQPAGTQPNQPNAQGDKRLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 711, "header": "tr|A0A8V0ZD19-1|A0A8V0ZD19_CHICK Isoform 1 of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0Z6D0-1", "sequence": { "sequence": "MRSHRTPAVQWGRVAALPRVPGHPLPICAHAAGGPSRDVVLVSAIITVSLSVTIVLCGICQWCQRRLGKRYKTSLETVGTPDSSRGRSEKKTINFEDSTLSTATTLEYIPTSAGDPKCQRPRTLMRQQSLQQPLSQHQRSNHSQPTTSQSLGHLQAHSSSSGGAGNPRGSRGGQARQGIAAGSKQRTSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQPAGTQPNQPNAQGDKRLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 586, "header": "tr|A0A8V0Z6D0-1|A0A8V0ZD19_CHICK Computationally mapped isoform of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 321373, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048729.1", "url": "https://www.ensembl.org/id/ENSGALT00010048729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028802.1", "url": "https://www.ensembl.org/id/ENSGALP00010028802.1" } ] } }, { "isoform_ac": "A0A8V0Z6D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0Z6D6-1", "sequence": { "sequence": "MYLDPEAASAGAVGWPRAPRRAVRPPSGPPGSALLCSSPGGPSRDVVLVSAIITVSLSVTIVLCGICQWCQRRLGKRYKTSLETVGTPDSSRGRSEKKTINDLDRDFWNNNDNTVQQKWSSYPPKEFILNISPYAPYGDPRLSLNFEDSTLSTATTLEYIPTSAGDPKCQRPRTLMRQQSLQQPLSQHQRSNHSQPTTSQSLGHLQAHSSSSGGAGNPRGSRGGQARQGIAAGSKQRTSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQPAGTQPNQPNAQGDKRLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 637, "header": "tr|A0A8V0Z6D6-1|A0A8V0ZD19_CHICK Computationally mapped isoform of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 326536, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048735.1", "url": "https://www.ensembl.org/id/ENSGALT00010048735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028807.1", "url": "https://www.ensembl.org/id/ENSGALP00010028807.1" } ] } }, { "isoform_ac": "A0A8V0ZD19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0ZD19-1", "sequence": { "sequence": "MPLFSAAAPCHAPAALHVGSTRRRTLFPIHEIHGHLKGAQQQCASPSVPTQRDPSALPAAACLLCSARARLHPRGRVVHRAIPARCGAPGTVVPRVLCWEGWGNGDGAGWLRHVSGRRVAPRDPPSHSSSLITQLADEVGRALRSHRAGGGGEMAPRERREAVPRPGGRETAGCSLWPLPERSLHWGIFSLTLFFSFLQFCPFTFFSFLSSPLPFLSLSFEDSTLSTATTLEYIPTSAGDPKCQRPRTLMRQQSLQQPLSQHQRSNHSQPTTSQSLGHLQAHSSSSGGAGNPRGSRGGQARQGIAAGSKQRTSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQPAGTQPNQPNAQGDKRLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 711, "header": "tr|A0A8V0ZD19-1|A0A8V0ZD19_CHICK Isoform 1 of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 317827, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048693.1", "url": "https://www.ensembl.org/id/ENSGALT00010048693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028771.1", "url": "https://www.ensembl.org/id/ENSGALP00010028771.1" } ] } }, { "isoform_ac": "A0A8V0ZD30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0ZD30-1", "sequence": { "sequence": "MGSTHAPSSSSSSSSSNPPPPPVPWAAPWRRATPGPPGSAGWCCTFGAGLLSPLFFLVCFLPLWIDAILPRTPSSPPLPPPAPFILTSFFFFFFFFGCADVSLSLSLSVRPLSVCPPPALCPPPCPSSHHGSLTRPSVYPAPFHVCPGGVRLPARPSGSLLSGAKLTASATAGLAGDRDGRPGDKQQCAEDGMRSSISAHSEPGAGKAARGRWHTVQSHLAAGKLSLSKLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 560, "header": "tr|A0A8V0ZD30-1|A0A8V0ZD30_CHICK Computationally mapped isoform of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 319784, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048704.1", "url": "https://www.ensembl.org/id/ENSGALT00010048704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028781.1", "url": "https://www.ensembl.org/id/ENSGALP00010028781.1" } ] } }, { "isoform_ac": "A0A8V0ZDL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0ZDL2-1", "sequence": { "sequence": "VVKAPRLHLPQKCGVGVEEPWPGGPSRDVVLVSAIITVSLSVTIVLCGICQWCQRRLGKRYKTSLETVGTPDSSRGRSEKKTINDLDRDFWNNNDNTVQQKWSSYPPKEFILNISPYAPYGDPRLSLKG", "length": 129, "header": "tr|A0A8V0ZDL2-1|A0A8V0ZDL2_CHICK Computationally mapped isoform of Synaptotagmin 7 OS=Gallus gallus OX=9031 GN=SYT7 PE=4 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 329554, "end_pos": 319294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048721.1", "url": "https://www.ensembl.org/id/ENSGALT00010048721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028795.1", "url": "https://www.ensembl.org/id/ENSGALP00010028795.1" } ] } }, { "isoform_ac": "A0A8V0ZDM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0ZDM2-1", "sequence": { "sequence": "MRSHRTPAVQWGRVAALPRVPGHPLPICAHAAGGPSRDVVLVSAIITVSLSVTIVLCGICQWCQRRLGKRYKTSLETVGTPDSSRGRSEKKTIKLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 425, "header": "tr|A0A8V0ZDM2-1|A0A8V0ZDM2_CHICK Computationally mapped isoform of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 321373, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048733.1", "url": "https://www.ensembl.org/id/ENSGALT00010048733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028805.1", "url": "https://www.ensembl.org/id/ENSGALP00010028805.1" } ] } }, { "isoform_ac": "A0A8V0ZDM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19/entry#A0A8V0ZDM6-1", "sequence": { "sequence": "MYLDPEAASAGGPSRDVVLVSAIITVSLSVTIVLCGICQWCQRRLGKRYKTSLETVGTPDSSRGRSEKKTINDLDRDFWNNNDNTVQQKWSSYPPKEFILNISPYAPYGDPRLSLNGSLLSGAKLTASATAGLAGDRDGRPGDKQQCAEDGMRSSISAHSEPGAGKAARGRWHTVQSHLAAGKLSLSNFEDSTLSTATTLEYIPTSAGDPKCQRPRTLMRQQSLQQPLSQHQRSNHSQPTTSQSLGHLQAHSSSSGGAGNPRGSRGGQARQGIAAGSKQRTSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQPAGTQPNQPNAQGDKRLPAGGKAVNTAPVPGQTQQDESDRKTEPHSSVSDLVNSLTSEMLMLSPGSEDDEGHDGSSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIVVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPVFNESFSFDIPTERLRETTIVITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQAVAQWHQLKA", "length": 680, "header": "tr|A0A8V0ZDM6-1|A0A8V0ZDM6_CHICK Computationally mapped isoform of Synaptotagmin-7 OS=Gallus gallus OX=9031 GN=SYT7 PE=3 SV=1 CANONICAL=A0A8V0ZD19-1" }, "locus": { "chromosome": "5", "start_pos": 326536, "end_pos": 311884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048738.1", "url": "https://www.ensembl.org/id/ENSGALT00010048738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028810.1", "url": "https://www.ensembl.org/id/ENSGALP00010028810.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101748423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748423", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "calcium ion regulated lysosome exocytosis", "id": "GO:1990927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990927", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "positive regulation of transport", "id": "GO:0051050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD19" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 563, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 509, "end_pos": 511 }, { "start_pos": 642, "end_pos": 644 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD89-1", "uniprot_ac": "A0A8V0ZD89", "uniprot_id": "A0A8V0ZD89_CHICK", "mass": { "chemical_mass": 70075.0, "monoisotopic_mass": 70075.0 }, "refseq": { "ac": "XP_046799310", "name": "xaa-Pro aminopeptidase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046799310" }, "gene_names": [ { "name": "XPNPEP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ] }, { "name": "XPNPEP1", "type": "synonym", "evidence": [ { "id": "XP_046799310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046799310" } ] } ], "protein_names": [ { "name": "Xaa-Pro aminopeptidase 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "3.4.11.9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "Aminoacylproline aminopeptidase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "Cytosolic aminopeptidase P", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "Soluble aminopeptidase P", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "X-Pro aminopeptidase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "X-prolyl aminopeptidase 1, soluble", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#names_and_taxonomy" } ] }, { "name": "xaa-Pro aminopeptidase 1", "type": "synonym", "evidence": [ { "id": "XP_046799310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046799310" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046799310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046799310" } ] }, { "annotation": "Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Contributes to the degradation of bradykinin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC96#function" }, { "database": "UniProtKB", "id": "ARBA00054066", "url": "https://www.uniprot.org/uniprotkb/ARBA00054066#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E6#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F1#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XPNPEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89", "locus": { "chromosome": "6", "start_pos": 26468319, "end_pos": 26498747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020183", "url": "https://www.ensembl.org/id/ENSGALG00010020183" } ] } } ], "crossref": [ { "id": "A0A8V0ZD89", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD89", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423886", "url": "https://www.ncbi.nlm.nih.gov/gene/423886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EPGMILS", "url": "https://omabrowser.org/oma/group/EPGMILS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6E6", "url": "https://www.orthodb.org/?gene=A0A8V0Z6E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6F1", "url": "https://www.orthodb.org/?gene=A0A8V0Z6F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6G8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC96", "url": "https://www.orthodb.org/?gene=A0A8V0ZC96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD74", "url": "https://www.orthodb.org/?gene=A0A8V0ZD74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD89", "url": "https://www.orthodb.org/?gene=A0A8V0ZD89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDQ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43763:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43763:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046799310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046799310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 623, "header": "tr|A0A8V0ZD89-1|A0A8V0ZD89_CHICK Isoform 1 of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0Z6E6-1", "sequence": { "sequence": "MMCGHFKSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 591, "header": "tr|A0A8V0Z6E6-1|A0A8V0ZD89_CHICK Computationally mapped isoform of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26490168, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048752.1", "url": "https://www.ensembl.org/id/ENSGALT00010048752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028817.1", "url": "https://www.ensembl.org/id/ENSGALP00010028817.1" } ] } }, { "isoform_ac": "A0A8V0Z6F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0Z6F1-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 621, "header": "tr|A0A8V0Z6F1-1|A0A8V0ZD89_CHICK Computationally mapped isoform of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048759.1", "url": "https://www.ensembl.org/id/ENSGALT00010048759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028822.1", "url": "https://www.ensembl.org/id/ENSGALP00010028822.1" } ] } }, { "isoform_ac": "A0A8V0Z6G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0Z6G8-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRRDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 573, "header": "tr|A0A8V0Z6G8-1|A0A8V0ZD89_CHICK Computationally mapped isoform of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048780.1", "url": "https://www.ensembl.org/id/ENSGALT00010048780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028837.1", "url": "https://www.ensembl.org/id/ENSGALP00010028837.1" } ] } }, { "isoform_ac": "A0A8V0ZC96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0ZC96-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 599, "header": "tr|A0A8V0ZC96-1|A0A8V0ZC96_CHICK Computationally mapped isoform of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048770.1", "url": "https://www.ensembl.org/id/ENSGALT00010048770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028829.1", "url": "https://www.ensembl.org/id/ENSGALP00010028829.1" } ] } }, { "isoform_ac": "A0A8V0ZD74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0ZD74-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 565, "header": "tr|A0A8V0ZD74-1|A0A8V0ZD74_CHICK Computationally mapped isoform of X-prolyl aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048765.1", "url": "https://www.ensembl.org/id/ENSGALT00010048765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028826.1", "url": "https://www.ensembl.org/id/ENSGALP00010028826.1" } ] } }, { "isoform_ac": "A0A8V0ZD89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0ZD89-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSKVGVDPSIIPADQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 623, "header": "tr|A0A8V0ZD89-1|A0A8V0ZD89_CHICK Isoform 1 of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048786.1", "url": "https://www.ensembl.org/id/ENSGALT00010048786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028841.1", "url": "https://www.ensembl.org/id/ENSGALP00010028841.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89/entry#A0A8V0ZDQ0-1", "sequence": { "sequence": "MSPKITTELLKQLRQVMKSPRYVQEPVQAYIVPSGDAHQSEYIAPCDCRRAFISGFDGSAGTAIVTEQHAAMWTDGRYFLQAANQMDNNWTLMKMDQWKRMSKVLRSAGHDLVPVKENLIDTIWTDRPQRPCKPLIVLDLSYTGVSWRDKIVALRSKMAERKVVWFVVTALDEVAWLFNLRGSDVEYNPVFFAYAVIGMNTIRLFIDGDRMMDPAVREHLQLDSTLEPEFKIQVMPYRSILTELQAVGAGLSPKEKVWLSDKASYALTEAIPKAYRYLTPYTPICIAKAVKNALETEGMRRAHIKDAVALCELFNWLEKEVPKGTVTEIIAADKAEEFRSQQKDFVELSFATISSTGPNGAIIHYKPVPETNRTLSVNEIYLLDSGAQYKDGTTDVTRTMHFGTPSAYEKECFTYVLKGHIAVSAAIFPNGTKGHLLDSFARSALWDCGLDYLHGTGHGVGSFLNVHEGPCGISYKTFADEPLEAGMIVSDEPGYYEDGSFGIRIENVVLVIPAETKYNFKNRGSLTFEPLTLVPIQTKMIDVSLLTQKECNWVNDYHQKCREVIGAELERQGRHEALRWLIRETEPLIRVQ", "length": 592, "header": "tr|A0A8V0ZDQ0-1|A0A8V0ZDQ0_CHICK Computationally mapped isoform of Xaa-Pro aminopeptidase 1 OS=Gallus gallus OX=9031 GN=XPNPEP1 PE=1 SV=1 CANONICAL=A0A8V0ZD89-1" }, "locus": { "chromosome": "6", "start_pos": 26494987, "end_pos": 26469145, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048777.1", "url": "https://www.ensembl.org/id/ENSGALT00010048777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028835.1", "url": "https://www.ensembl.org/id/ENSGALP00010028835.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "O54975-1", "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "Xpnpep1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKVTSELLRQLRQAMRNSECVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERSIVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLERIMLFIDGDRIDAPGVKQHLLLDLGLEAEYKIQVLPYKSILSELKTLCADLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKAVKNSAESAGMRRAHIKDAVALCELFNWLEQEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPIPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDALTDKECDWLNSYHQTCRDVIGKELQTQGRQEALEWLLRETEPISRQH", "length": 623 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q07825-1", "protein_name": "Putative Xaa-Pro aminopeptidase FRA1", "gene_name": "FRA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTSKPSTSDGRAHSISHVPGTHMRGTSASHSPRPFRPCADCTCSPGLLSRQGRRASLFLRQLENSRRSSSMLLNELKGAGGGSSAGNGSVYSCDSLCAVNREVNTTDRLLKLRQEMKKHDLCCYIVPSCDEHQSEYVSLRDQRRAFISGFSGSAGVACITRDLLNFNDDHPDGKSILSTDGRYFNQARQELDYNWTLLRQNEDPITWQEWCVREALEMAKGLGNKEGMVLKIGIDPKLITFNDYVSFRKMIDTKYDAKGKVELVPVEENLVDSIWPDFETLPERPCNDLLLLKYEFHGEEFKDKKEKLLKKLNDKASSATTGRNTFIVVALDEICWLLNLRGSDIDYNPVFFSYVAINEDETILFTNNPFNDDISEYFKINGIEVRPYEQIWEHLTKITSQASSAEHEFLIPDSASWQMVRCLNTSTNANGAIAKKMTAQNFAIIHSPIDVLKSIKNDIEIKNAHKAQVKDAVCLVQYFAWLEQQLVGREALIDEYRAAEKLTEIRKTQRNFMGNSFETISSTGSNAAIIHYSPPVENSSMIDPTKIYLCDSGSQFLEGTTDITRTIHLTKPTKEEMDNYTLVLKGGLALERLIFPENTPGFNIDAIARQFLWSRGLDYKHGTGHGIGSFLNVHEGPMGVGFRPHLMNFPLRAGNIISNEPGYYKDGEYGIRIESDMLIKKATEKGNFLKFENMTVVPYCRKLINTKLLNEEEKTQINEYHARVWRTIVHFLQPQSISYKWLKRETSPL", "length": 749 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1JPJ2-1", "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "XPNPEP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKITSELLRQLRQAMRNLEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIVTEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKDNLVDKIWTDRPERPCKPLITLGLDYTGISWKDKVADLRLKMAERNVVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAILGLETIMLFIDGDRIDAPIVKEHLLLDLGLEAEYRIQVLPYKSILSELKILCASLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAANKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNSYHLTCRDVIGKELQKQGRQEALEWLIRETQPISKQP", "length": 623 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54G06-1", "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "xpnpep1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQRVLNKIISKDTINTMGKVAISKKVEKLRTFMKDQSLSAYIVPSEDAHQSEYICVKDKRREYISGFSGSAGCVVITLDNQLLWTDGRYWLQAEKELESNWKIMKDRVVGEPTIQDWLLSNLNKENKVGIDSRLISKGYYDSMKLVLKEKSIDIKFDEDGENLIDKVRESFKDEEEIPEYPKNSIFFLEDKFTGKQSNEKLKEIREEMKKQSADLMVVSALDEIAWLLNLRGSDISFNPVFLSYVVVEHEKVTLFVDESKLNDKTKSQLPSGIAISPYSSVFEYLRNSDKQGKKIWIDPRSSVALYNCVSISNLLEKINPILLSKAIKNETEIQGMKNAHIRDAVALIQFLAWMEEEIVEKSDETSHTEYSVCEKLEGFRRQQTDFVSLSFDTISSINANGAIIHYKPDETTSATIVKGMYLVDSGAQYLDGTTDVTRTLHYGKPTQHEIDCYTRVLRGHVGLSLLKFPNRVNGRDIDCVARTHLWSVGLDYAHGTGHGVGSFLNVHEGPQGISYRAIANPTNLQAGMTLTNEPGYYESGNFGIRIENVMIVAPVTTQFNNGKFIGFDNITLVPYERKLINLEMLTKDEINFINDYYKEIGEKILPLIEKTNNQKSINWLKNQIKPL", "length": 627 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P1B1-1", "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "Xpnpep1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKVTSELLRQLRQAMRNSEYVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERSIAWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIVGLETIMLFIDGDRVDAPGVKQHLLLDLGLEAEYRIQVLPYKSILSELKALCADLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKAVKNSAESDGMRRAHIKDAVALCELFNWLEQEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVNALTDKECDWLNSYHQTCRDVVGKELQSQGRQEALEWLIRETEPVSRQH", "length": 623 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RY11-1", "protein_name": "Aminopeptidase P2", "gene_name": "APP2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIPLTLSSPSLNRLVLSTSRYSHSLFLSNFNSLSLIHRKLPYKPLFGARCHASSSSSSSSSFTAKSSKEIRKAQTKVVVDEKLSSIRRLFSEPGVGIDAYIIPSQDAHQSEFIAECYARRAYISGFTGSAGTAVVTKDKAALWTDGRYFLQAEKQLNSSWILMRAGNPGVPTASEWIADVLAPGGRVGIDPFLFSADAAEELKEVIAKKNHELVYLYNVNLVDEIWKDSRPKPPSRQIRIHDLKYAGLDVASKLLSLRNQIMDAGTSAIVISMLDEIAWVLNLRGSDVPHSPVMYAYLIVEVDQAQLFVDNSKVTVEVKDHLKNAGIELRPYDSILQGIDSLAARGAQLLMDPSTLNVAIISTYKSACERYSRNFESEAKVKTKFTDSSSGYTANPSGIYMQSPISWAKAIKNDAELKGMKNSHLRDAAALAHFWAWLEEEVHKNANLTEVDVADRLLEFRSMQDGFMDTSFDTISGSGANGAIIHYKPEPESCSRVDPQKLFLLDSGAQYVDGTTDITRTVHFSEPSAREKECFTRVLQGHIALDQAVFPEGTPGFVLDGFARSSLWKIGLDYRHGTGHGVGAALNVHEGPQSISFRYGNMTPLQNGMIVSNEPGYYEDHAFGIRIENLLHVRDAETPNRFGGATYLGFEKLTFFPIQTKMVDVSLLSDTEVDWLNSYHAEVWEKVSPLLEGSTTQQWLWNNTRPLAKP", "length": 710 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NQW7-1", "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "XPNPEP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKDKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKELQKQGRQEALEWLIRETQPISKQH", "length": 623 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJG0-1", "protein_name": "Xaa-Pro aminopeptidase ApepP", "gene_name": "ApepP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRSTTQILTRLRELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVITTETALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSFVGVDPRLLSFRVWKPIETELSSAECQLVPIEGNLIDEVWGEDQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKNADALVVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVDSGKLPTDFVQHQKENNVQISVLPYASIGIEISKIVSTRESKIWIAPTSSYYLTALIPKSRRIQEVTPICVLKAIKNDVEIAGFINSHIRDGVALCQYFAWLEDQVNKGAEVDEMSGADKLESFRSTKDKYMGLSFTTISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI", "length": 613 }, "evidence": [ { "id": "A0A8V0ZD89", "url": "https://omabrowser.org/oma/group/A0A8V0ZD89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" }, { "name": "bradykinin catabolic process", "id": "GO:0010815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD89" } ], "pmid": "" }, { 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"homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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] }, { "name": "2.1.1.319", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#names_and_taxonomy" } ] }, { "name": "Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRMT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7", "locus": { "chromosome": "5", "start_pos": 2366628, "end_pos": 2296258, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020215", "url": "https://www.ensembl.org/id/ENSGALG00010020215" } ] } } ], "crossref": [ { "id": "A0A8V0ZDB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003958", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003958", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422975", "url": "https://www.ncbi.nlm.nih.gov/gene/422975", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422975", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422975", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSHFAIH", "url": "https://omabrowser.org/oma/group/YSHFAIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6I8", "url": "https://www.orthodb.org/?gene=A0A8V0Z6I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDB2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDB2", "database": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF21137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "48096", "url": "https://www.rhea-db.org/rhea/48096", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48100", "url": "https://www.rhea-db.org/rhea/48100", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYG2", "url": "https://www.uniprot.org/uniprotkb/F1NYG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYG2-1", "url": "https://www.uniprot.org/uniprotkb/F1NYG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMRASCGIEKDLPKNLFNSAEEATSFAQGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRWFCSPEDVFCHCNAEHQFNVRDVVVKHGLDFYGYVKLINFVRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKHIDCNAASTLDLEFSSEFTLTIRTSTKCTAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 543, "header": "tr|A0A8V0ZDB7-1|A0A8V0ZDB7_CHICK Isoform 1 of Protein arginine N-methyltransferase 3 OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=1 CANONICAL=A0A8V0ZDB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#A0A8V0Z6I8-1", "sequence": { "sequence": "MDSRVEGAALPGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRWFCSPEDVFCHCNAEHQFNVRDVVVKHGLDFYGYVKLINFVRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKEEKYSLKKDKHIDCNAASTLDLEFSSEFTLTIRTSTKCTAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 536, "header": "tr|A0A8V0Z6I8-1|A0A8V0ZDB7_CHICK Computationally mapped isoform of Protein arginine N-methyltransferase 3 OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=1 CANONICAL=A0A8V0ZDB7-1" }, "locus": { "chromosome": "5", "start_pos": 2363883, "end_pos": 2309924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048816.1", "url": "https://www.ensembl.org/id/ENSGALT00010048816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028857.1", "url": "https://www.ensembl.org/id/ENSGALP00010028857.1" } ] } }, { "isoform_ac": "A0A8V0ZDB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#A0A8V0ZDB2-1", "sequence": { "sequence": "MDSRVEGAALPGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKHIDCNAASTLDLEFSSEFTLTIRTSTKCTAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 484, "header": "tr|A0A8V0ZDB2-1|A0A8V0ZDB2_CHICK Computationally mapped isoform of Protein arginine N-methyltransferase 3 OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=1 CANONICAL=A0A8V0ZDB7-1" }, "locus": { "chromosome": "5", "start_pos": 2363883, "end_pos": 2309924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048826.1", "url": "https://www.ensembl.org/id/ENSGALT00010048826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028861.1", "url": "https://www.ensembl.org/id/ENSGALP00010028861.1" } ] } }, { "isoform_ac": "A0A8V0ZDB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#A0A8V0ZDB7-1", "sequence": { "sequence": "MMRASCGIEKDLPKNLFNSAEEATSFAQGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRWFCSPEDVFCHCNAEHQFNVRDVVVKHGLDFYGYVKLINFVRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKHIDCNAASTLDLEFSSEFTLTIRTSTKCTAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 543, "header": "tr|A0A8V0ZDB7-1|A0A8V0ZDB7_CHICK Isoform 1 of Protein arginine N-methyltransferase 3 OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=1 CANONICAL=A0A8V0ZDB7-1" }, "locus": { "chromosome": "5", "start_pos": 2363883, "end_pos": 2300571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048833.1", "url": "https://www.ensembl.org/id/ENSGALT00010048833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028866.1", "url": "https://www.ensembl.org/id/ENSGALP00010028866.1" } ] } }, { "isoform_ac": "A0A8V0ZJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#A0A8V0ZJS9-1", "sequence": { "sequence": "MDSRVEGAALPGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRWFCSPEDVFCHCNAEHQFNVRDVVVKHGLDFYGYVKLINFVRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 497, "header": "tr|A0A8V0ZJS9-1|A0A8V0ZJS9_CHICK Computationally mapped isoform of type I protein arginine methyltransferase OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=1 CANONICAL=A0A8V0ZDB7-1" }, "locus": { "chromosome": "5", "start_pos": 2363883, "end_pos": 2309924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048819.1", "url": "https://www.ensembl.org/id/ENSGALT00010048819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028858.1", "url": "https://www.ensembl.org/id/ENSGALP00010028858.1" } ] } }, { "isoform_ac": "F1NYG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7/entry#F1NYG2-1", "sequence": { "sequence": "MDSRVEGAALPGPTRDDEMAELSDGEEAWEEEEEQQEQGTGEGLRARCLFCDRWFCSPEDVFCHCNAEHQFNVRDVVVKHGLDFYGYVKLINFVRLKKPMPAYLNSLSSPLPWDGEEYLKPELEDDLLLQFDTEDLCEPTDILCSNGLNDTTVLLKQLKHAEHRARLAEAALARAQDDLHKMRQFAQDFVMNADVGSSSSSNTIADLHEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIGVDQSEIIYQAMDIIRLNKLENTITLIKGRIEEVDLPLEKVDVIISEWMGYFLLFESMLDSVIYAKDKYLAEGGSVYPDICTISLVAVGDMDKHIEKLLFWEDVYGFDMSCMKKAVIPEAVVEVLDPSTLISEASIIKHIDCNAASTLDLEFSSEFTLTIRTSTKCTAIAGYFDIFFEKGCHNKVLFSTGPLCTKTHWKQTVFLLEKPIPVEAGEALRGKITVRKNRKDPRSLLITLLVKDVKQTYSLQ", "length": 526, "header": "tr|F1NYG2-1|A0A8V0ZDB7_CHICK Computationally mapped isoform of Protein arginine N-methyltransferase 3 OS=Gallus gallus OX=9031 GN=PRMT3 PE=1 SV=2 CANONICAL=A0A8V0ZDB7-1" }, "locus": { "chromosome": "5", "start_pos": 2363883, "end_pos": 2309924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048823.1", "url": "https://www.ensembl.org/id/ENSGALT00010048823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028859.1", "url": "https://www.ensembl.org/id/ENSGALP00010028859.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422975", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422975", "resource": "KEGG Pathway" }, { "id": "R-GGA-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-GGA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "O60678-1", "protein_name": "Protein arginine N-methyltransferase 3", "gene_name": "PRMT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCSLASGATGGRGAVENEEDLPELSDSGDEAAWEDEDDADLPHGKQQTPCLFCNRLFTSAEETFSHCKSEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ", "length": 531 }, "evidence": [ { "id": "A0A8V0ZDB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70467-1", "protein_name": "Protein arginine N-methyltransferase 3", "gene_name": "Prmt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCSLAAGNGQGAELGPEPLELSDSGDDAGWEDEDADAEPAQGRQHTPCLFCDRLFRSAEETFSHCKLEHQFNIDGMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWDKDEYLKPVLEDDLLLQFDVEDLYEPVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ", "length": 528 }, "evidence": [ { "id": "A0A8V0ZDB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0WVD6-1", "protein_name": "Probable protein arginine N-methyltransferase 3", "gene_name": "PRMT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAATMVKHEILNYSEDEEENYSDEGDWGDWKADDNGIEGGEEEEEDDGDDSESDFLCLFCDSHFVSCDLLFEHCRLSHGFDFHGVRKELKLDFYSSFKLINYIRSQVAENMCFSWKIEADDYKDVKFPWDEEKYLKPFWQEDSLLYSFADDEEDEEVTFDREEVMEELQKLGDLSIDVEALGESSMSNSDKCNINGSKDVTSLSNCNGLKQSSADDLIVNGKDAEPKVCDGRLVNRNIRKVNENYFGSYSSFGIHREMLSDKVRTEAYRDALLKNPTLLNGSVVMDVGCGTGILSLFAAKAGASRVVAVEASEKMAKVATKIAKDNKVFNDNEHNGVLEVAHSMVEELDKSIQIQPHSVDVLVSEWMGYCLLYESMLSSVLYARDRWLKPGGAILPDTATMFVAGFGKGATSLPFWEDVYGFDMSSIGKEIHDDTTRLPIVDVIAERDLVTQPTLLQTFDLATMKPDEVDFTATATLEPTESEAKTRLCHGVVLWFDTGFTSRFCKENPTVLSTSPYTPPTHWAQTILTFQEPISVAPASVLSGNDRREAIGTEECPASSIHLRVSVARAHEHRSIDISLEATGLSSKGQKRHWPVQIFNL", "length": 601 }, "evidence": [ { "id": "A0A8V0ZDB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDB7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q922H1-1", "protein_name": "Protein arginine N-methyltransferase 3", "gene_name": "Prmt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCSLAAGNGRGAELGPEPLELSDSGDDAGWEDEDADTEPAHGRQHTPCLFCDRLFASAEETFSHCKLEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKDEYLKPVLEDDLLLQFDVEDLYEPVSTPFSYPNGLSESASVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ", "length": 528 }, "evidence": [ { "id": "A0A8V0ZDB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFB3-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "Art3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKDTEVNDNTTEEEPVKEAPEVPANSSSDEDEYDDIDDDDEPMDEGDELTTCLFCTETSANISVAIDHLDARHKVNLSQLQRKFEMDQYSFIKLINYIRAKKISAEQLLSAEHPLWQDEKYLQPGEYEPWLCYDYEVLKTDGAPTQPSVLELQQRIAEQSQLLQQANEDMERMRNDYKALLQKVHADGEPKGSDQSVPRNNVCLDNEYFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKAGAARVVGIDNSDIVYTAMDIIRKNKVENVELIKGRLEDTDLPETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSLLGYGDDTLYADEVEFWSNVYEVDMSDLRKQSIEEPLMQVVDAEFMLTEPEQIANFDIMTVDMNYPNFTHQFSLKVTKPGRLSAFVGYFETLFELPSPVMFSTSPSATPTHWKQTVFFIENPQVVKEGDVICGKITSRRHKEDVRGLSVDIEVFGKKHKYNVV", "length": 516 }, "evidence": [ { "id": "A0A8V0ZDB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDB7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "protein-arginine N-methyltransferase activity", "id": "GO:0016274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "histone H4R3 methyltransferase activity", "id": "GO:0044020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" }, { "name": "negative regulation of retinoic acid biosynthetic process", "id": "GO:1900053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48096", "name": "", "equation": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZDB7-1", "F1NJK8-1" ], "evidence": [ { "id": "48096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48096" } ] }, { "id": "48100", "name": "", "equation": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZIB9-1", "A0A8V0ZYF3-1", "A0A8V0ZDB7-1", "F1NJK8-1" ], "evidence": [ { "id": "48100", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48100" } ] }, { "id": "R-GGA-8879123", "name": "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-72347" ], "output_participant_list": [ "R-GGA-8879138" ], "enzyme_list": [ "A0A8V0ZDB7-1" ], "evidence": [ { "id": "R-GGA-8879123", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8879123" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-72347", "participant_name": "RPS2 [cytosol]", "crossref": [ { "id": "A0A8V0Z985", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010018867", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010027191", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010045596", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-8879138", "participant_name": "RPS2 [cytosol]", "crossref": [ { "id": "A0A8V0Z985", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010027191", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010045596", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010018867", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZDB7", "gene_name": "PRMT3", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ] } ] }, { "uniprot_ac": "A0A8V0ZYF3", "gene_name": "PRMT7", "activity": [ { "ec_number": "2.1.1.321", "activity": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0ZYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYF3" } ] }, { "ec_number": "2.1.1.321", "activity": "", "evidence": [ { "id": "A0A8V0ZYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYF3" } ] } ] }, { "uniprot_ac": "F1NJK8", "gene_name": "PRMT1", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ] } ] }, { "uniprot_ac": "Q5ZIB9", "gene_name": "PRMT7", "activity": [ { "ec_number": "2.1.1.321", "activity": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q5ZIB9", "database": "UniProtKB", "url": 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"uniprotkb_annotation": "Protein arginine N-methyltransferase 3-like C2H2 zinc finger", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 138, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.319", "ec_name": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "2.1.1.319", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319" }, { "id": "2.1.1.319", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.319" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCD1-1", "uniprot_ac": "A0A8V0ZCD1", "uniprot_id": "A0A8V0ZCD1_CHICK", "mass": { "chemical_mass": 83237.0, "monoisotopic_mass": 83237.0 }, "refseq": {}, "gene_names": [ { "name": "ADD3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ] } ], "protein_names": [ { "name": "Adducin 3 (gamma)", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "common_name": 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"https://www.ebi.ac.uk/interpro/entry/IPR036409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:373892", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XVRISKE", "url": "https://omabrowser.org/oma/group/XVRISKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6K0", "url": "https://www.orthodb.org/?gene=A0A8V0Z6K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCD1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZJS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NEA1", "url": "https://www.orthodb.org/?gene=F1NEA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10672:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10672:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00596", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00596", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6K0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NEA1", "url": "https://www.uniprot.org/uniprotkb/F1NEA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NEA1-1", "url": "https://www.uniprot.org/uniprotkb/F1NEA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTDASQVVITSPPAATMPHKERYFDRINENDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLVRAHLWQRPCSLWELLSVGSAAVWQMILSGFFASLKMKGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEDAEQELFSDDGSSVSQIQSQTQSPQNVPEKLEENHADLYTQSANLISAELPVVVVNGKEDAHDVEEDLTKRVSQLTTSTVESVEITIKSSEKIEEALSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEV", "length": 747, "header": "tr|A0A8V0ZCD1-1|A0A8V0ZCD1_CHICK Isoform 1 of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=1 CANONICAL=A0A8V0ZCD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6K0-1", "url": 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"end_pos": 26575257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048835.1", "url": "https://www.ensembl.org/id/ENSGALT00010048835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028867.1", "url": "https://www.ensembl.org/id/ENSGALP00010028867.1" } ] } }, { "isoform_ac": "A0A8V0ZCD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#A0A8V0ZCD1-1", "sequence": { "sequence": "MSTDASQVVITSPPAATMPHKERYFDRINENDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLVRAHLWQRPCSLWELLSVGSAAVWQMILSGFFASLKMKGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEDAEQELFSDDGSSVSQIQSQTQSPQNVPEKLEENHADLYTQSANLISAELPVVVVNGKEDAHDVEEDLTKRVSQLTTSTVESVEITIKSSEKIEEALSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEV", "length": 747, "header": "tr|A0A8V0ZCD1-1|A0A8V0ZCD1_CHICK Isoform 1 of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=1 CANONICAL=A0A8V0ZCD1-1" }, "locus": { "chromosome": "6", "start_pos": 26599364, "end_pos": 26575257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048830.1", "url": "https://www.ensembl.org/id/ENSGALT00010048830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028864.1", "url": "https://www.ensembl.org/id/ENSGALP00010028864.1" } ] } }, { "isoform_ac": "A0A8V0ZDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#A0A8V0ZDA7-1", "sequence": { "sequence": "MSTDASQVVITSPPAATMPHKERYFDRINENDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEDLYTQSANLISAELPVVVVNGKEDAHDVEEDLTKRVSQLTTSTVESVEITIKSSEKIEEALSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEV", "length": 673, "header": "tr|A0A8V0ZDA7-1|A0A8V0ZDA7_CHICK Computationally mapped isoform of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=1 CANONICAL=A0A8V0ZCD1-1" }, "locus": { "chromosome": "6", "start_pos": 26599364, "end_pos": 26575257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048815.1", "url": "https://www.ensembl.org/id/ENSGALT00010048815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028856.1", "url": "https://www.ensembl.org/id/ENSGALP00010028856.1" } ] } }, { "isoform_ac": "A0A8V0ZDS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#A0A8V0ZDS3-1", "sequence": { "sequence": "MSTDASQVVITSPPAATMPHKERYFDRINENDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEEIPHPVFPEEEQKERESGSVSAALLGGDGAHFKRLG", "length": 614, "header": "tr|A0A8V0ZDS3-1|A0A8V0ZDS3_CHICK Computationally mapped isoform of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=1 CANONICAL=A0A8V0ZCD1-1" }, "locus": { "chromosome": "6", "start_pos": 26599414, "end_pos": 26575257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048824.1", "url": "https://www.ensembl.org/id/ENSGALT00010048824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028860.1", "url": "https://www.ensembl.org/id/ENSGALP00010028860.1" } ] } }, { "isoform_ac": "A0A8V0ZJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#A0A8V0ZJS3-1", "sequence": { "sequence": "MHSAWFASRPLAPWNKAPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEDAEQELFSDDGSSVSQIQSQTQSPQNVPEKLEENHADLYTQSANLISAELPVVVVNGKEDAHDVEEDLTKRVSQLTTSTVESVEITIKSSEKIEEALSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEV", "length": 662, "header": "tr|A0A8V0ZJS3-1|A0A8V0ZJS3_CHICK Computationally mapped isoform of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=1 CANONICAL=A0A8V0ZCD1-1" }, "locus": { "chromosome": "6", "start_pos": 26599364, "end_pos": 26581442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048809.1", "url": "https://www.ensembl.org/id/ENSGALT00010048809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028853.1", "url": "https://www.ensembl.org/id/ENSGALP00010028853.1" } ] } }, { "isoform_ac": "F1NEA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1/entry#F1NEA1-1", "sequence": { "sequence": "MSTDASQVVITSPPAATMPHKERYFDRINENDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGNNPTGLLALQQIADYITASSFAGFSSSSLSHGMITPINDLPGIDTSSFVKGEKLTRCKLASLYRLADLFGWAHLPNAYITVRVSKEHDHILIIPRGLSFSEASASNLIKVNILGDVVDQGSTTLSIDSAGFSPHVAIYSTRPDVRCVIHIHTPATAAVSSMKCGILPISQEALILGDVAYYNYQGSLDDQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACETQVHALAGAGGIDNLLLLDLQKFKPFTHGVAAGGGGGVNMSSQQKWKVGEQEFEALMRMLDNLGYRTGYAYRQPLVREKPRHKSDVEIPATVTAFSFEDDAVPLSPLKFLAQRQQREKTRWLNSPNTYLKVNVPEESWNGEASPRTKITWMKADDSSKTSGGTPIKIEDPNQFVPLNTNPSEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKKPSPPMQFEDDEHAPPAPPNPFSHLTEKELEEYKKTIERKQLGLEDAEQELFSDDGSSVSQIQSQTQSPQNVPEKLEENHADLYTQSANLISAELPVVVVNGKEDAHDVEEDLTKRVSQLTTSTVESVEITIKSSEKIEEALSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEV", "length": 709, "header": "tr|F1NEA1-1|A0A8V0ZCD1_CHICK Computationally mapped isoform of Adducin 3 (gamma) OS=Gallus gallus OX=9031 GN=ADD3 PE=1 SV=2 CANONICAL=A0A8V0ZCD1-1" }, "locus": { "chromosome": "6", "start_pos": 26599364, "end_pos": 26575257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048838.1", "url": "https://www.ensembl.org/id/ENSGALT00010048838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028870.1", "url": "https://www.ensembl.org/id/ENSGALP00010028870.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:373892", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373892", "resource": "KEGG Pathway" }, { "id": "R-GGA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TIC1-1", "protein_name": "Adducin 3", "gene_name": "ADD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSDASQGVVTTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFTSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHVHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEQEERIQLQKVLGPSCKVLVLRNHGVVALGETVEEAFHYIFNVQIACEIQVQALAGAGGVDNLLVLDLQKYKAFTHSVAASGGGGVNMGSHQKWKIGELEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSSGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHAPPAPPNPFSHLTEGELEEYKKTIERKQQGLEENHELFSKSFISMDVPVLIVNGKDDVHGIEDELAQRVSRLTTSTTIENIEITIKSPEKIEEVPSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA", "length": 674 }, "evidence": [ { "id": "A0A8V0ZCD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZCD1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q62847-1", "protein_name": "Gamma-adducin", "gene_name": "Add3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSDTSQAVITTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHDPTGLLALQQIADYIMANSFTGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRVSKEQDHIIIIPRGLSFSEATASALVKVNIIGEVVDQGSTNLKIDHSGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLILDLQKYKAFTHGVAMTGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVREKPRHKSDVEIPATVTAFSFEDDSVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDPSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMRFEDDDQGPPAPPNPFSHLMEGELEEYTKTIERKQQGLDDAEQESLSDDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSVDVPVIVNGKDEMHDVEDELAQRVSRLTTSTTIENIEITIKSPDRTEEVLSPDGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA", "length": 705 }, "evidence": [ { "id": "A0A8V0ZCD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZCD1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QYB5-1", "protein_name": "Gamma-adducin", "gene_name": "Add3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSDTSPAVVTTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPSGLLALQQIADYIVTSSFSGFSSPSLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVREKPRHKSDVEIPATVTAFSFEDDSAPLSPLKFMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFDDDDQGPPAPPNPFSHLLEGELEEYTKTIERKQQGLDDAEQGSLSDDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSMDAPVMIMNGKDEMHDVEDELAQRVSRLTTSTTIENIEITIKSPERTEEVLSPDGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA", "length": 706 }, "evidence": [ { "id": "A0A8V0ZCD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZCD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UEY8-1", "protein_name": "Gamma-adducin", "gene_name": "ADD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA", "length": 706 }, "evidence": [ { "id": "A0A8V0ZCD1", "url": "https://omabrowser.org/oma/group/A0A8V0ZCD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD1" }, { "id": "SM01007", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Class II aldolase/adducin N-terminal", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 321, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 357, "end_pos": 359 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"length": 1160, "header": "tr|A0A8V0Z6L1-1|A0A8V0ZCH9_CHICK Computationally mapped isoform of Cilia and flagella associated protein 61 OS=Gallus gallus OX=9031 GN=CFAP61 PE=1 SV=1 CANONICAL=A0A8V0ZCH9-1" }, "locus": { "chromosome": "3", "start_pos": 4100808, "end_pos": 4010423, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044091.1", "url": "https://www.ensembl.org/id/ENSGALT00010044091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026209.1", "url": "https://www.ensembl.org/id/ENSGALP00010026209.1" } ] } }, { "isoform_ac": "A0A8V0ZCH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9/entry#A0A8V0ZCH9-1", "sequence": { "sequence": "MTAITSLRGHTEVVHSRRTEAHDASAFVGLFTHFTEDIFGRIDVAYLLEKSTFALTLCNEKNEAIAHAIFLDYPNWNITDQSDWESFLNKNYVNNKCTPLNTLFMHLFVAKEEYAAGCSQEIIRRTFIAIPELQFILLFIPADENLEPGLDGVFEKMMTAPGSTVGKTFTLLVCPRHPYHPQLHVRKARLEDYDDLMPIWTRQSEILKETHGEYFLADITACQDEENQAVVCEDDGAVVGFMSLCSQVDISLLRESFDLRLFHGLCKPHPEDVLEVPKEPSIPEDEDKSDQRSQEAETISSQNLEDINDEDAAVQKDGAITISHTKLPLDDVIHTDFHASATSLLEVEEKDTFHPIYKGASNAFCIRLFCIDEKYETRSLDFLHYVFKLFPDKDFCIILVPHCVPEFYLIQSFFRVAPSCTSQLGRELYMFHCAGLLKSFNVRRATTNDILGVKTLIKTLTLNESILNDLNTFILARRDPDGTPVQAFVAEVLDQIVGISVIRDEMDIVYIQTHYNIEDFIHFNDYQQEEHGELYHFVLNPIFRHYTKHFLKEILRLAHKSSLFYPIYPQYAEGKFQNPFAHSLTSALHYMVPVRPRRQIVYPLEELGINAPSEQVSKDQPRYSLNHINRKLIMESKVSVNSRIVVVGASDVGISFLETLVFCPHLKFNNLTLISTHGLPGKDLPGSKHRRFLINSHCFNDEDYAQMSLCSWVNVVVGKMTGINRSAKYVVVSKERRVPYDYLVLCTGLSYQVLSPTGSHTSELTTNRDDISKWPQRYTGKIPSNHFTLNDDQDCLKAMEWLKENFINSEGNVIVYGNTIDIYTTIETFLSLGIDGSRIHLVQPPLSSNVTCLNNTEIESAVQEALSEAGVAVYCDSILAEWSKGDDPDLITCAAFSTNTKPFQLQCSAFFSFAYKRVDYETFKAINDACLVFDGKLVIDTEFRTNDVSIRAAGPLTKYSRRYYADEWTHSNFNSKEIGFELAASMLSLFDPTPQLFSEPPEGMDGLIPMYKGCKIQGGVLPRGYNYLHISKPEVPIRLDLVLALSDHGTEIVTGKARDGNYFRMHINKYSMVDSITCFSKEPFPASNYICLYGQHERLLNDLSYRWNEGQIADLYSYFRAPCCMAIYHDRFIDLQKELRQILLSEQVPPEQQTEDSPVSPLLAGPAVRYLLRHGAQLPMYARGRPAGFNFYTWK", "length": 1195, "header": "tr|A0A8V0ZCH9-1|A0A8V0ZCH9_CHICK Isoform 1 of Cilia and flagella associated protein 61 OS=Gallus gallus OX=9031 GN=CFAP61 PE=1 SV=1 CANONICAL=A0A8V0ZCH9-1" }, "locus": { "chromosome": "3", "start_pos": 4100808, "end_pos": 4007226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044101.1", "url": "https://www.ensembl.org/id/ENSGALT00010044101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026218.1", "url": "https://www.ensembl.org/id/ENSGALP00010026218.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9" }, { "id": "PF23150", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23150" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP61 dimerisation", "eco_id": "ECO_0000259", "start_pos": 1009, "end_pos": 1127, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH9" }, { "id": "PF16092", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cilia- and flagella-associated protein 61 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 268, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 463, "end_pos": 465 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 849, "end_pos": 851 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCG7-1", "uniprot_ac": "A0A8V0ZCG7", "uniprot_id": "A0A8V0ZCG7_CHICK", "mass": { "chemical_mass": 64716.0, "monoisotopic_mass": 64716.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF710", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ] } ], "protein_names": [ { "name": "Zinc finger protein 710", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF710", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7", "locus": { "chromosome": "10", "start_pos": 20054227, "end_pos": 20038797, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020257", "url": "https://www.ensembl.org/id/ENSGALG00010020257" } ] } } ], "crossref": [ { "id": "A0A8V0ZCG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6N3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGPHLCCAAMTTRGTDMDRFTECGTQTDAVVVLSLAQAAVLGLVSDNELLGATVSPAGFFPGLGGEGEPDITAEPESEGMAPDGQEDESLEAECSPEKHARRRKRPPVRLLPKVKREEAEAEVFEVAVPEEDEADLQHGAPPAPPPDPTPEPSGVVKMIDLSTFSRKPRRLRHLRRHTRQQPHGREPNPAQGTAQTPCAFEAGAPSPGEPEAPASPERVKSEQGFSWQEPGEMEADAAGDNSEHSKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCNKLFKQPSHLQTHLLTHQGTRAAQVRGVQQGVHADQPPEAAHAAAHRHQALQLPLLRPRLRLPQRAEGTRGEARERPLPRLRGVRAGLLHAHPAEAAPGHAPGPHAVPVPGVQQVLPLPQPAAEPHAEAPECPALCLHRVRHGVQPDPPPQAALAHAQGREGVQVRGVRARVHAAGQHEAAHAHPHQRPALPVPHLLQDVCAEADAEDPHDCALTGEAIQVQGLREVLQPHVQPAGPHAPARGQQALQVPLLLQQVQLERQPEPAHEGQAWRDGHQSGQSRSHDGPVWG", "length": 598, "header": "tr|A0A8V0ZCG7-1|A0A8V0ZCG7_CHICK Isoform 1 of Zinc finger protein 710 OS=Gallus gallus OX=9031 GN=ZNF710 PE=4 SV=1 CANONICAL=A0A8V0ZCG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7/entry#A0A8V0Z6N3-1", "sequence": { "sequence": "MLCTLSFAMTTRGTDMDRFTECGTQTDAVVVLSLAQAAVLGLVSDNELLGATVSPAGFFPGLGGEGEPDITAEPESEGMAPDGQEDESLEAECSPEKHARRRKRPPVRLLPKVKREEAEAEVFEVAVPEEDEADLQHGAPPAPPPDPTPEPSGVVKMIDLSTFSRKPRRLRHLRRHTRQQPHGREPNPAQGTAQTPCAFEAGAPSPGEPEAPASPERVKSEQGFSWQEPGEMEADAAGDNSEHSKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCNKLFKQPSHLQTHLLTHQGTRAAQVRGVQQGVHADQPPEAAHAAAHRHQALQLPLLRPRLRLPQRAEGTRGEARERPLPRLRGVRAGLLHAHPAEAAPGHAPGPHAVPVPGVQQVLPLPQPAAEPHAEAPECPALCLHRVRHGVQPDPPPQAALAHAQGREGVQVRGVRARVHAAGQHEAAHAHPHQRPALPVPHLLQDVCAEADAEDPHDCALTGEAIQVQGLREVLQPHVQPAGPHAPARGQQALQVPLLLQQVQLERQPEPAHEGQAWRDGHQSGQSRSHDGPVWG", "length": 595, "header": "tr|A0A8V0Z6N3-1|A0A8V0ZCG7_CHICK Computationally mapped isoform of Zinc finger protein 710 OS=Gallus gallus OX=9031 GN=ZNF710 PE=4 SV=1 CANONICAL=A0A8V0ZCG7-1" }, "locus": { "chromosome": "10", "start_pos": 20052556, "end_pos": 20049891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048889.1", "url": "https://www.ensembl.org/id/ENSGALT00010048889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028897.1", "url": "https://www.ensembl.org/id/ENSGALP00010028897.1" } ] } }, { "isoform_ac": "A0A8V0ZCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7/entry#A0A8V0ZCG7-1", "sequence": { "sequence": "MAEGPHLCCAAMTTRGTDMDRFTECGTQTDAVVVLSLAQAAVLGLVSDNELLGATVSPAGFFPGLGGEGEPDITAEPESEGMAPDGQEDESLEAECSPEKHARRRKRPPVRLLPKVKREEAEAEVFEVAVPEEDEADLQHGAPPAPPPDPTPEPSGVVKMIDLSTFSRKPRRLRHLRRHTRQQPHGREPNPAQGTAQTPCAFEAGAPSPGEPEAPASPERVKSEQGFSWQEPGEMEADAAGDNSEHSKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCNKLFKQPSHLQTHLLTHQGTRAAQVRGVQQGVHADQPPEAAHAAAHRHQALQLPLLRPRLRLPQRAEGTRGEARERPLPRLRGVRAGLLHAHPAEAAPGHAPGPHAVPVPGVQQVLPLPQPAAEPHAEAPECPALCLHRVRHGVQPDPPPQAALAHAQGREGVQVRGVRARVHAAGQHEAAHAHPHQRPALPVPHLLQDVCAEADAEDPHDCALTGEAIQVQGLREVLQPHVQPAGPHAPARGQQALQVPLLLQQVQLERQPEPAHEGQAWRDGHQSGQSRSHDGPVWG", "length": 598, "header": "tr|A0A8V0ZCG7-1|A0A8V0ZCG7_CHICK Isoform 1 of Zinc finger protein 710 OS=Gallus gallus OX=9031 GN=ZNF710 PE=4 SV=1 CANONICAL=A0A8V0ZCG7-1" }, "locus": { "chromosome": "10", "start_pos": 20052556, "end_pos": 20044901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048891.1", "url": "https://www.ensembl.org/id/ENSGALT00010048891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028899.1", "url": "https://www.ensembl.org/id/ENSGALP00010028899.1" } ] } }, { "isoform_ac": "A0A8V0ZDF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7/entry#A0A8V0ZDF4-1", "sequence": { "sequence": "MTTRGTDMDRFTECGTQTDAVVVLSLAQAAVLGLVSDNELLGATVSPAGFFPGLGGEGEPDITAEPESEGMAPDGQEDESLEAECSPEKHARRRKRPPVRLLPKVKREEAEAEVFEVAVPEEDEADLQHGAPPAPPPDPTPEPSGVVKMIDLSTFSRKPRRLRHLRRHTRQQPHGREPNPAQGTAQTPCAFEAGAPSPGEPEAPASPERVKSEQGFSWQEPGEMEADAAGDNSEHSKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCNKLFKQPSHLQTHLLTHQGTRAAQVRGVQQGVHADQPPEAAHAAAHRHQALQLPLLRPRLRLPQRAEGTRGEARERPLPRLRGVRAGLLHAHPAEAAPGHAPGPHAVPVPGVQQVLPLPQPAAEPHAEAPECPALCLHRVRHGVQPDPPPQAALAHAQGREGVQVRGVRARVHAAGQHEAAHAHPHQRPALPVPHLLQDVCAEADAEDPHDCALTGEAIQVQGLREVLQPHVQPAGPHAPARGQQALQVPLLLQQVQLERQPEPAHEGQAWRDGHQSGQSRSHDGPVWG", "length": 587, "header": "tr|A0A8V0ZDF4-1|A0A8V0ZDF4_CHICK Computationally mapped isoform of Zinc finger protein 710 OS=Gallus gallus OX=9031 GN=ZNF710 PE=4 SV=1 CANONICAL=A0A8V0ZCG7-1" }, "locus": { "chromosome": "10", "start_pos": 20052556, "end_pos": 20050100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048894.1", "url": "https://www.ensembl.org/id/ENSGALT00010048894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028901.1", "url": "https://www.ensembl.org/id/ENSGALP00010028901.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 303, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 151 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDH9-1", "uniprot_ac": "A0A8V0ZDH9", "uniprot_id": "A0A8V0ZDH9_CHICK", "mass": { "chemical_mass": 82227.0, "monoisotopic_mass": 82227.0 }, "refseq": {}, "gene_names": [ { "name": "FBXO42", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9" } ] } ], "protein_names": [ { "name": "F-box protein 42", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9", "locus": { "chromosome": "21", "start_pos": 4327830, "end_pos": 4367318, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020283", "url": "https://www.ensembl.org/id/ENSGALG00010020283" } ] } } ], "crossref": [ { "id": "A0A8V0ZDH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419461", "url": "https://www.ncbi.nlm.nih.gov/gene/419461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419461", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z6R1", "url": "https://www.orthodb.org/?gene=A0A8V0Z6R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46432:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46432:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSVLSAAARAAAAAALREDGGAGASRHPGDAAAPAPAAVRARLGLACPRPGPAAVKWNAMASSSDSEDDSFMAVDPEEAVVEGTMEQDEEPHAELEVEEPRHNRSMLELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFIKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIEDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDETILILGGCGGPNALFKDAWLLHMQANPWTWQPLKVENEDHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRTTDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDSSPVLNGGSLSPGAAAPGGASLDSPVQLISPGTPGATEGCELKVGLALAPRRGSLPEQKDLRLGSIDLSWEQKTASLCQTDGADSRTLRNPPEHTNGIHTPPHSLPGAVSPGALRRSLEAIKALSSKAPPASAALSPPLGSSPGSPGSQGSGADARPGSAQGDSHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFTSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR", "length": 764, "header": "tr|A0A8V0ZDH9-1|A0A8V0ZDH9_CHICK Isoform 1 of F-box protein 42 OS=Gallus gallus OX=9031 GN=FBXO42 PE=4 SV=1 CANONICAL=A0A8V0ZDH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9/entry#A0A8V0Z6R1-1", "sequence": { "sequence": "MASSSDSEDDSFMAVDPEEAVVEGTMEQDEEPHAELEEHKTAALVCKQWYRLIKGVAHQCYHGFIKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIEDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDETILILGGCGGPNALFKDAWLLHMQANPWTWQPLKVENEDHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRTTDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDSSPVLNGGSLSPGAAAPGGASLDSPVQLISPGTPGATEGCELKVGLALAPRRGSLPEQKDLRLGSIDLSWEQKTASLCQTDGADSRTLRNPPEHTNGIHTPPHSLPGAVSPGALRRSLEAIKALSSKAPPASAALSPPLGSSPGSPGSQGSGADARPGSAQGDSHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFTSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR", "length": 675, "header": "tr|A0A8V0Z6R1-1|A0A8V0ZDH9_CHICK Computationally mapped isoform of F-box protein 42 OS=Gallus gallus OX=9031 GN=FBXO42 PE=4 SV=1 CANONICAL=A0A8V0ZDH9-1" }, "locus": { "chromosome": "21", "start_pos": 4357389, "end_pos": 4329424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048938.1", "url": "https://www.ensembl.org/id/ENSGALT00010048938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028923.1", "url": "https://www.ensembl.org/id/ENSGALP00010028923.1" } ] } }, { "isoform_ac": "A0A8V0ZDH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9/entry#A0A8V0ZDH5-1", "sequence": { "sequence": "MGTTNATYACELGSVGPGVMPAAVKWNAMASSSDSEDDSFMAVDPEEAVVEGTMEQDEEPHAELEVEEPRHNRSMLELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFIKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIEDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDETILILGGCGGPNALFKDAWLLHMQANPWTWQPLKVENEDHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRTTDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDSSPVLNGGSLSPGAAAPGGASLDSPVQLISPGTPGATEGCELKVGLALAPRRGSLPEQKDLRLGSIDLSWEQKTASLCQTDGADSRTLRNPPEHTNGIHTPPHSLPGAVSPGALRRSLEAIKALSSKAPPASAALSPPLGSSPGSPGSQGSGADARPGSAQGDSHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFTSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR", "length": 732, "header": "tr|A0A8V0ZDH5-1|A0A8V0ZDH5_CHICK Computationally mapped isoform of F-box protein 42 OS=Gallus gallus OX=9031 GN=FBXO42 PE=4 SV=1 CANONICAL=A0A8V0ZDH9-1" }, "locus": { "chromosome": "21", "start_pos": 4360569, "end_pos": 4329424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048935.1", "url": "https://www.ensembl.org/id/ENSGALT00010048935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028922.1", "url": "https://www.ensembl.org/id/ENSGALP00010028922.1" } ] } }, { "isoform_ac": "A0A8V0ZDH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9/entry#A0A8V0ZDH9-1", "sequence": { "sequence": "MCSVLSAAARAAAAAALREDGGAGASRHPGDAAAPAPAAVRARLGLACPRPGPAAVKWNAMASSSDSEDDSFMAVDPEEAVVEGTMEQDEEPHAELEVEEPRHNRSMLELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFIKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIEDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDETILILGGCGGPNALFKDAWLLHMQANPWTWQPLKVENEDHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRTTDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDSSPVLNGGSLSPGAAAPGGASLDSPVQLISPGTPGATEGCELKVGLALAPRRGSLPEQKDLRLGSIDLSWEQKTASLCQTDGADSRTLRNPPEHTNGIHTPPHSLPGAVSPGALRRSLEAIKALSSKAPPASAALSPPLGSSPGSPGSQGSGADARPGSAQGDSHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFTSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR", "length": 764, "header": "tr|A0A8V0ZDH9-1|A0A8V0ZDH9_CHICK Isoform 1 of F-box protein 42 OS=Gallus gallus OX=9031 GN=FBXO42 PE=4 SV=1 CANONICAL=A0A8V0ZDH9-1" }, "locus": { "chromosome": "21", "start_pos": 4367294, "end_pos": 4329424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048944.1", "url": "https://www.ensembl.org/id/ENSGALT00010048944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028927.1", "url": "https://www.ensembl.org/id/ENSGALP00010028927.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 438, "start_aa": "Thr", "end_pos": 438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr438", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419461", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH9" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 153, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 438 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCJ7-1", "uniprot_ac": "A0A8V0ZCJ7", "uniprot_id": "A0A8V0ZCJ7_CHICK", "mass": { "chemical_mass": 157586.0, "monoisotopic_mass": 157586.0 }, "refseq": { "ac": "XP_040502299", "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502299" }, "gene_names": [ { "name": "MAGI1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ] }, { "name": "MAGI1", "type": "synonym", "evidence": [ { "id": "XP_040502299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502299" } ] } ], "protein_names": [ { "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#names_and_taxonomy" } ] }, { "name": "BAI1-associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#names_and_taxonomy" } ] }, { "name": "Membrane-associated guanylate kinase inverted 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#names_and_taxonomy" } ] }, { "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X12", "type": "synonym", "evidence": [ { "id": "XP_040502299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502299" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502299" } ] }, { "annotation": "Plays a role in coupling actin fibers to cell junctions in endothelial cells, via its interaction with AMOTL2 and CDH5. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R6#function" }, { "database": "UniProtKB", "id": "ARBA00058771", "url": "https://www.uniprot.org/uniprotkb/ARBA00058771#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7", "locus": { "chromosome": "12", "start_pos": 14182652, "end_pos": 14474383, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020282", "url": "https://www.ensembl.org/id/ENSGALG00010020282" } ] } } ], "crossref": [ { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06732", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06732", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416083", "url": "https://www.ncbi.nlm.nih.gov/gene/416083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6R6", "url": "https://www.orthodb.org/?gene=A0A8V0Z6R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCJ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDI4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJZ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZJZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040502299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRVVQKKNHWASRVRQCVLSRGPGGQLGFVLLGGAEHGEFPYAGAVAAGGGEQALSEGELLLEVQGVRVSGLPRYDVLEVIRSCKEPIVVKAVRQGSRLNKDLRHYLNQRFQKGSPDHDLQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLTVEEFLELERSGTLLEVGTYEGNYYGTPKPPSQPLSGKVTSTDALQNLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEDDAPEMSSSFTAESGDQDEHHTHIVRETAPPSAIDSHTNLPTTEPSQSLPQYLPPSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLSKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQPPEGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQENYDSPASHSSKTGKVNGTKEARPSSPAEVSSNGPHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQSLTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSSHRSGHTASPAHSTQVLPEYPAAEPPAADQPDASGQKKPDPFKIWAQSRSMYESRPMSPSPATGLSKGEREREINSTSFGEFPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADADGRLRSGDELICVDGTPVVGKSHQLVVQLMQQAAKQGHVNLTVRRKVVYTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPQQIPQETSRNNTKPKQESQFDFKPPQAAQQDQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHARAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRNSPATGSQNVSEMKPVPSDRRQHPSLESSYPPDLHKSSQHGDKRTYVRDLKGSREVSRHPNEHHTWNGTCKANDTVPGRRTERSPERRRERQPERAAVNGQKRRSPEKQRREGTRSADNTLERRERHERRRDLSPERRRERSPGRRRRSLERLTEPRRSPERRRENSLDRRAKSSDRRRERSPERRLREERAGHRQREDASWKQEASRRHPTEQRRRPYKECSTDLSI", "length": 1423, "header": "tr|A0A8V0ZCJ7-1|A0A8V0ZCJ7_CHICK Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MAGI1 PE=1 SV=1 CANONICAL=A0A8V0ZCJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#A0A8V0Z6R6-1", "sequence": { "sequence": "MSRVVQKKNHWASRVRQCVLSRGPGGQLGFVLLGGAEHGEFPYAGAVAAGGGEQALSEGELLLEVQGVRVSGLPRYDVLEVIRSCKEPIVVKAVRQGSRLNKDLRHYLNQRFQKGSPDHDLQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLTVEEFLELERSGTLLEVGTYEGNYYGTPKPPSQPLSGKVTSTDALQNLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEDDAPEMSSSFTAESGDQDEHHTHIVRETAPPSAIDSHTNLPTTEPSQSLPQYLPPSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLSKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQPPEGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQENYDSPASHSSKTGKVNGTKEARPSSPAEVSSNGPHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQSLTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSSHRSGHTASPAHSTQVLPEYPAAEPPAADQPDASGQKKPDPFKIWAQSRSMYESRPMSPSPATGLSKGEREREINSTSFGEFPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADADGRLRSGDELICVDGTPVVGKSHQLVVQLMQQAAKQGHVNLTVRRKVVYTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFESSNATLLTNAEKIATITTTHTPQQIPQETSRNNTKPKQESQFDFKPPQAAQQDQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHARAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRNSPATGSQNVSEMKPVPSDRRQHPSLESSYPPDLHKSSQHGDKRTYVRDLKGSREVSRHPNEHHTWNGTCKANDTVPGRRTERSPERRRERQPERAAVNGQKRRSPEKQRREGTRSADNTLERRERHERRRDLSPERRRERSPGRRRRSLERLTEPRRSPERRRENSLDRRAKSSDRRRERSPERRLREERAGHRQREDASWKQEASRRHPTEQRRRPYKECSTDLSI", "length": 1355, "header": "tr|A0A8V0Z6R6-1|A0A8V0ZCJ7_CHICK Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MAGI1 PE=1 SV=1 CANONICAL=A0A8V0ZCJ7-1" }, "locus": { "chromosome": "12", "start_pos": 14474184, "end_pos": 14183777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048945.1", "url": "https://www.ensembl.org/id/ENSGALT00010048945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028928.1", "url": "https://www.ensembl.org/id/ENSGALP00010028928.1" } ] } }, { "isoform_ac": "A0A8V0ZCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#A0A8V0ZCJ7-1", "sequence": { "sequence": "MSRVVQKKNHWASRVRQCVLSRGPGGQLGFVLLGGAEHGEFPYAGAVAAGGGEQALSEGELLLEVQGVRVSGLPRYDVLEVIRSCKEPIVVKAVRQGSRLNKDLRHYLNQRFQKGSPDHDLQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLTVEEFLELERSGTLLEVGTYEGNYYGTPKPPSQPLSGKVTSTDALQNLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEDDAPEMSSSFTAESGDQDEHHTHIVRETAPPSAIDSHTNLPTTEPSQSLPQYLPPSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLSKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQPPEGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQENYDSPASHSSKTGKVNGTKEARPSSPAEVSSNGPHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQSLTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSSHRSGHTASPAHSTQVLPEYPAAEPPAADQPDASGQKKPDPFKIWAQSRSMYESRPMSPSPATGLSKGEREREINSTSFGEFPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADADGRLRSGDELICVDGTPVVGKSHQLVVQLMQQAAKQGHVNLTVRRKVVYTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPQQIPQETSRNNTKPKQESQFDFKPPQAAQQDQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHARAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRNSPATGSQNVSEMKPVPSDRRQHPSLESSYPPDLHKSSQHGDKRTYVRDLKGSREVSRHPNEHHTWNGTCKANDTVPGRRTERSPERRRERQPERAAVNGQKRRSPEKQRREGTRSADNTLERRERHERRRDLSPERRRERSPGRRRRSLERLTEPRRSPERRRENSLDRRAKSSDRRRERSPERRLREERAGHRQREDASWKQEASRRHPTEQRRRPYKECSTDLSI", "length": 1423, "header": "tr|A0A8V0ZCJ7-1|A0A8V0ZCJ7_CHICK Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MAGI1 PE=1 SV=1 CANONICAL=A0A8V0ZCJ7-1" }, "locus": { "chromosome": "12", "start_pos": 14474184, "end_pos": 14183777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048947.1", "url": "https://www.ensembl.org/id/ENSGALT00010048947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028930.1", "url": "https://www.ensembl.org/id/ENSGALP00010028930.1" } ] } }, { "isoform_ac": "A0A8V0ZDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#A0A8V0ZDI4-1", "sequence": { "sequence": "MSRVVQKKNHWASRVRQCVLSRGPGGQLGFVLLGGAEHGEFPYAGAVAAGGGEQALSEGELLLEVQGVRVSGLPRYDVLEVIRSCKEPIVVKAVRQGSRLNKDLRHYLNQRFQKGSPDHDLQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLTVEEFLELERSGTLLEVGTYEGNYYGTPKPPSQPLSGKVTSTDALQNLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEDDAPEMSSSFTAESGDQDEHHTHIVRETAPPSAIDSHTNLPTTEPSQSLPQYLPPSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLSKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQPPEGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQENYDSPASHSSKTGKVNGTKEARPSSPAEVSSNGPHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQSLTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSSHRSGHTASPAHSTQVLPEYPAAEPPAADQPDASGQKKPDPFKIWAQSRSMYESRLPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADADGRLRSGDELICVDGTPVVGKSHQLVVQLMQQAAKQGHVNLTVRRKVVYTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPQQIPQETSRNNTKPKQESQFDFKPPQAAQQDQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHARAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRNSPATGSQNVSEMKPVPSDRRQHPSLESSYPPDLHKSSQHGDKRTYVRDLKGSREVSRHPNEHHTWNGTCKANDTVPGRRTERSPERRRERQPERAAVNGQKRRSPEKQRREGTRSADNTLERRERHERRRDLSPERRRERSPGRRRRSLERLTEPRRSPERRRENSLDRRAKSSDRRRERSPERRLREERAGHRQREDASWKQEASRRHPTEQRRRPYKECSTDLSI", "length": 1397, "header": "tr|A0A8V0ZDI4-1|A0A8V0ZDI4_CHICK Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MAGI1 PE=1 SV=1 CANONICAL=A0A8V0ZCJ7-1" }, "locus": { "chromosome": "12", "start_pos": 14474184, "end_pos": 14183777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048949.1", "url": "https://www.ensembl.org/id/ENSGALT00010048949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028932.1", "url": "https://www.ensembl.org/id/ENSGALP00010028932.1" } ] } }, { "isoform_ac": "A0A8V0ZDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7/entry#A0A8V0ZDY1-1", "sequence": { "sequence": "MEGSVALRLDARTRGGYQAITHLLGLGPGRSGSRKYRNEQGSRLNKDLRHYLNQRFQKGSPDHDLQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLTVEEFLELERSGTLLEVGTYEGNYYGTPKPPSQPLSGKVTSTDALQNLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEDDAPEMSSSFTAESGDQDEHHTHIVRETAPPSAIDSHTNLPTTEPSQSLPQYLPPSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLSKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQPPEGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQENYDSPASHSSKTGKVNGTKEARPSSPAEVSSNGPHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQSLTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSSHRSGHTASPAHSTQVLPEYPAAEPPAADQPDASGQKKPDPFKIWAQSRSMYESRPMSPSPATGLSKGEREREINSTSFGEFPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADADGRLRSGDELICVDGTPVVGKSHQLVVQLMQQAAKQGHVNLTVRRKVVYTVPKAENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPQQIPQETSRNNTKPKQESQFDFKPPQAAQQDQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHARAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRNSPATGSQNVSEMKPVPSDRRQHPSLESSYPPDLHKSSQHGDKRTYVRDLKGSREVSRHPNEHHTWNGTCKANDTVPGRRTERSPERRRERQPERAAVNGQKRRSPEKQRREGTRSADNTLERRERHERRRDLSPERRRERSPGRRRRSLERLTEPRRSPERRRENSLDRRAKSSDRRRERSPERRLREERAGHRQREDASWKQEASRRHPTEQRRRPYKECSTDLSI", 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"length": 1373, "header": "tr|A0A8V0ZJZ4-1|A0A8V0ZJZ4_CHICK Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MAGI1 PE=1 SV=1 CANONICAL=A0A8V0ZCJ7-1" }, "locus": { "chromosome": "12", "start_pos": 14474184, "end_pos": 14183777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048939.1", "url": "https://www.ensembl.org/id/ENSGALT00010048939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028924.1", "url": "https://www.ensembl.org/id/ENSGALP00010028924.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" } ] }, { "name": 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"UniProtKB", "id": "A0A8V0ZCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1075, "end_pos": 1077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1262, "end_pos": 1264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1268, "end_pos": 1270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": 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"name": "SNX29", "type": "synonym", "evidence": [ { "id": "XP_040539775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539775" } ] } ], "protein_names": [ { "name": "Sorting nexin 29", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-29 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040539775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539775" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052586.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040539775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539775" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8", "locus": { "chromosome": "14", "start_pos": 242816, "end_pos": 158133, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020291", "url": "https://www.ensembl.org/id/ENSGALG00010020291" } ] } } ], "crossref": [ { "id": "A0A8V0ZCM8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07277", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07277", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416417", "url": "https://www.ncbi.nlm.nih.gov/gene/416417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6V6", "url": "https://www.orthodb.org/?gene=A0A8V0Z6V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6W2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCL7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCM8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDK2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE29", "url": "https://www.orthodb.org/?gene=A0A8V0ZE29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK04", "url": "https://www.orthodb.org/?gene=A0A8V0ZK04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK14", "url": "https://www.orthodb.org/?gene=A0A8V0ZK14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK25", "url": "https://www.orthodb.org/?gene=A0A8V0ZK25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040539775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAEEALRWRLPAWSRVYFPGRRGGFPGRCVCGAQAGLGLRGLRECVWQRDAASPVATMSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGNNSQINGLIQEVADGKSLFQHALL", "length": 895, "header": "tr|A0A8V0ZCM8-1|A0A8V0ZCM8_CHICK Isoform 1 of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0Z6V6-1", "sequence": { "sequence": "MSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVK", "length": 774, "header": "tr|A0A8V0Z6V6-1|A0A8V0ZCM8_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 230607, "end_pos": 158437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048992.1", "url": "https://www.ensembl.org/id/ENSGALT00010048992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028963.1", "url": "https://www.ensembl.org/id/ENSGALP00010028963.1" } ] } }, { "isoform_ac": "A0A8V0Z6W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0Z6W2-1", "sequence": { "sequence": "MSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGNNSQINGLIQEVADVRFPTSLGYF", "length": 837, "header": "tr|A0A8V0Z6W2-1|A0A8V0ZCM8_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 231018, "end_pos": 158437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048998.1", "url": "https://www.ensembl.org/id/ENSGALT00010048998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028968.1", "url": "https://www.ensembl.org/id/ENSGALP00010028968.1" } ] } }, { "isoform_ac": "A0A8V0ZCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZCL7-1", "sequence": { "sequence": "MRAEEALRWRLPAWSRVYFPGRRGGFPGRCVCGAQAGLGLRGLRECVWQRDAASPVATMSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVCSSGRT", "length": 837, "header": "tr|A0A8V0ZCL7-1|A0A8V0ZCL7_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 225011, "end_pos": 158263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048975.1", "url": "https://www.ensembl.org/id/ENSGALT00010048975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028950.1", "url": "https://www.ensembl.org/id/ENSGALP00010028950.1" } ] } }, { "isoform_ac": "A0A8V0ZCM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZCM8-1", "sequence": { "sequence": "MRAEEALRWRLPAWSRVYFPGRRGGFPGRCVCGAQAGLGLRGLRECVWQRDAASPVATMSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGNNSQINGLIQEVADGKSLFQHALL", "length": 895, "header": "tr|A0A8V0ZCM8-1|A0A8V0ZCM8_CHICK Isoform 1 of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 242099, "end_pos": 158263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048989.1", "url": "https://www.ensembl.org/id/ENSGALT00010048989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028960.1", "url": "https://www.ensembl.org/id/ENSGALP00010028960.1" } ] } }, { "isoform_ac": "A0A8V0ZDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZDI9-1", "sequence": { "sequence": "MSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETVSLRNFLPSFKCLFYAAYIEIVIRSQHDT", "length": 112, "header": "tr|A0A8V0ZDI9-1|A0A8V0ZDI9_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 170302, "end_pos": 158437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048956.1", "url": "https://www.ensembl.org/id/ENSGALT00010048956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028937.1", "url": "https://www.ensembl.org/id/ENSGALP00010028937.1" } ] } }, { "isoform_ac": "A0A8V0ZDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZDK2-1", "sequence": { "sequence": "MSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGNNSQINGLIQEVADVRFPTSLGYF", "length": 790, "header": "tr|A0A8V0ZDK2-1|A0A8V0ZDK2_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 231018, "end_pos": 158437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048972.1", "url": "https://www.ensembl.org/id/ENSGALT00010048972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028947.1", "url": "https://www.ensembl.org/id/ENSGALP00010028947.1" } ] } }, { "isoform_ac": "A0A8V0ZE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZE29-1", "sequence": { "sequence": "MRAEEALRWRLPAWSRVYFPGRRGGFPGRCVCGAQAGLGLRGLRECVWQRDAASPVATMSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGDL", "length": 873, "header": "tr|A0A8V0ZE29-1|A0A8V0ZE29_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 228546, "end_pos": 158263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048995.1", "url": "https://www.ensembl.org/id/ENSGALT00010048995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028966.1", "url": "https://www.ensembl.org/id/ENSGALP00010028966.1" } ] } }, { "isoform_ac": "A0A8V0ZK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZK04-1", "sequence": { "sequence": "MYRTSRGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETGNSLIIPILLKKKKVQGS", "length": 105, "header": "tr|A0A8V0ZK04-1|A0A8V0ZK04_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 167335, "end_pos": 161251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048951.1", "url": "https://www.ensembl.org/id/ENSGALT00010048951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028934.1", "url": "https://www.ensembl.org/id/ENSGALP00010028934.1" } ] } }, { "isoform_ac": "A0A8V0ZK14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZK14-1", "sequence": { "sequence": "MRAEEALRWRLPAWSRVYFPGRRGGFPGRCVCGAQAGLGLRGLRECVWQRDAASPVATMSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVDIPSSGEATSKSSCLRVTTRFPKLSRSHQREPRSLEPQSGKSLFQHALL", "length": 880, "header": "tr|A0A8V0ZK14-1|A0A8V0ZK14_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 242099, "end_pos": 158263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048966.1", "url": "https://www.ensembl.org/id/ENSGALT00010048966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028944.1", "url": "https://www.ensembl.org/id/ENSGALP00010028944.1" } ] } }, { "isoform_ac": "A0A8V0ZK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8/entry#A0A8V0ZK25-1", "sequence": { "sequence": "MSGSQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLRRSRGLALTAAAIKQAAGFSSKTETEPVFWYYVKEVLNKHELQRFYSLKTITTDIGRGRAWLRCALNEHSLERYVHMLLADKNRLSVFYEDWSFMMDEERSSMIPTMAAGLNSILFAINIDNRDLNGQSKCAPTVSDLLKESTQNVTSLLKESTQGVSSLLREITASSAVSILIKPDQDSDPLPVLSKNVNAELKYKKDRKKKKKVANIISFDEENDELNVADATRMPVAGQSSEENLDRSSVFILPSSETSHGKNLNGNESNHSWKSNSVSLNGEYEYQKLDVKSIDDEDADEDDLCGKTLGNKDTEVETESSEKPPEIVTCNSQICSWTPLQVLNYDSDVLFPVSAVDSYSQTDKLENGGGHENDAVELFPRRSDISYRVEVSPPAQVNTLNSMLPSATVPESMTVNELRQAIVAMMNRKDELEEQNRSLRNLLDGEMEHSAALRQEMDNWRRKVAEQEERHATKVQALARENEVLKVQLKKYVGAVQMLRREGQAVEVLPNVWSTDGELTVSEQKQVENNEELASSYERKLIEVAEMHGELIEFNERLHRALMAKETLVSHMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRSLHHKLQNKYQQVRTFNFPPKKAIGNKDAKFVEERRKQLQNYLRNVMNKVIQTVPEFTANPKKETLIQLMPFFVCLFGNSKLE", "length": 782, "header": "tr|A0A8V0ZK25-1|A0A8V0ZK25_CHICK Computationally mapped isoform of Sorting nexin 29 OS=Gallus gallus OX=9031 GN=SNX29 PE=4 SV=1 CANONICAL=A0A8V0ZCM8-1" }, "locus": { "chromosome": "14", "start_pos": 219209, "end_pos": 158437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048980.1", "url": "https://www.ensembl.org/id/ENSGALT00010048980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028954.1", "url": "https://www.ensembl.org/id/ENSGALP00010028954.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 714, "end_pos": 837, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM8" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 239, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 261, "end_pos": 263 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 872, "end_pos": 874 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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215164.0, "monoisotopic_mass": 215164.0 }, "refseq": {}, "gene_names": [ { "name": "THADA", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ] } ], "protein_names": [ { "name": "tRNA (32-2'-O)-methyltransferase regulator THADA", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z3#function" }, { "database": "UniProtKB", "id": "ARBA00035625", "url": "https://www.uniprot.org/uniprotkb/ARBA00035625#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK74#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THADA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55", "locus": { "chromosome": "3", "start_pos": 24672939, "end_pos": 24824476, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020314", "url": "https://www.ensembl.org/id/ENSGALG00010020314" } ] } } ], "crossref": [ { "id": "421398", "url": "https://www.ncbi.nlm.nih.gov/gene/421398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6Z3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDQ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE55", "url": "https://www.orthodb.org/?gene=A0A8V0ZE55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK74", "url": "https://www.orthodb.org/?gene=A0A8V0ZK74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14387:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLKKKKKEIQVDAFSLDCQQLEKLQGFSKAEEQNLASLLLHCAQLSNGIQQIQCIKQIMPLVKAMDQNSACDPMLKACLEILGETYFSLDVKNPLKKVLASSLNGLPEWFMTLAVQSFVCCLREELKTTDVYLYRKVLDNLASCMEDFNLGMMNISNTLSSVLTCSALSNNGNRIVQTRLMHDLLMAIKVAMMLVQKLQENIQGSLWKNHESFVWQSMCNLLKSSSDFLMDETLLQTVQTTSGLAFILFTKAMYEPAEELPSLVSDLLCGSRKLAGMPAWFVNNCGALCTEQLSDSVLLFLCHGALAMLDWKSGSMGENGEKLLLDIASVLLSLSSELKESSMATSLSRILAIWTNSALAALIPDSPNLKVKLNGNSEVVGKLLEYVYTHWEHPLDAVRHQSKLIFRNLLQIHRTIIAASDEKSDPFFARLTRRLLSLEWHVKGKYASLACLVECLGTENILQLDRSIPVQILNVMNDQSLAPYASDLLETMFTNHKVQFTSGSQKSTWIDQWHDVWVSPLLQILCEGNHDQTTYIIDYYLPKLLRCSPDSLSYMIRILQASADANLGSWSTRGALGALMACLRTARAHGHLELSNIMSRGLVSTESIKQGLVHQHNQVCIDALGLLCETHRSTEIVSVEEMQLILFFITYNLNSQSPSVRQQICSLLRKLFCRIRESSQVLYKWEQNKTKQELFEDSPKRNPLGILQKYQDFLSSLCDRLFEALFPGSSHPTRFSALSILGSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFSLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQIVARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKMDLLKMTIKELMSLASPSSEPPSAIPQVHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHPSLFLLLLILGKLYPSPMDGTYSALSMAPFVPFIIRCGHSPVYRSREMSGRALVPFVMINEVPHTVLSLLKGLPDSTSLCIRQNNIHGTLLQVSHLLQSYLDSKQLGNSDFEQGLSDIVTCIGSKLWLAKRPNPCLVTRAAFLDVLVMLSTHLGNSQKQGMQFVEFWEEMNRVISECELMTGIPYLTAVPGLVQYLQSITKLVISVLSVTSAADIQSSSSPTAMKIAKPPLSIVHLLHSEFHEVRLLALEAVLLWLKKVNAKQIAKEGGVLCLLVDLEGVLLSMTLKEKNLECFYKVLEILYNMDLRNVLPKIECSIKMNPNEFLTWSLDIMDNSNSTEVRSMALKFASKFVVHLLENHQQISEEVLKKWVQQLIYFCGDEQETEMLLAAAEVFRSITSLLLISEKLVLGLSDTLAMWKCVILLLQNEDLVVRDAAAEVLQVAQAEKKSSKGAGFMFRVMNAPLALDLAFGTLCEQLQQWGQTCAGIPVLLEWLLGDSDPRGGLEPSAPEEDECLFDKGEVNFWAEKLTSARLLGKHLLLLAQATHLALPDGGELDRLCRRAQDQAQLTARLLTALPPSPEFLKTAEFTKLAIQNEQISLCLKILNLLQSVGKGKDGNLKE", "length": 1920, "header": "tr|A0A8V0ZE55-1|A0A8V0ZE55_CHICK Isoform 1 of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Gallus gallus OX=9031 GN=THADA PE=3 SV=1 CANONICAL=A0A8V0ZE55-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55/entry#A0A8V0Z6Z3-1", "sequence": { "sequence": "MVLKKKKKEIQVDAFSLDCQQLEKLQGFSKAEEQNLASLLLHCAQLSNGIQQIQCIKQIMPLVKAMDQNSACDPMLKACLEILGETYFSLDVKNPLKKVLASSLNGLPEWFMTLAVQSFVCCLREELKTTDVYLYRKVLDNLASCMEDFNLGRASITNLFEEVLQFLQKALLDIQEENRSNNGNRIVQTRLMHDLLMAIKVAMMLVQKLQENIQGSLWKNHESFVWQSMCNLLKSSSDFLMDETLLQTVQTTSGLAFILFTKAMYEPAEELPSLVSDLLCGSRKLAGMPAWFVNNCGALCTEQLSDSVLLFLCHGALAMLDWKSGSMGENGEKLLLDIASVLLSLSSELKESSMATSLSRILAIWTNSALAALIPDSPNLKVKLNGNSEVVGKLLEYVYTHWEHPLDAVRHQSKLIFRNLLQIHRTIIAASDEKSDPFFARLTRRLLSLEWHVKGKYASLACLVECLGTENILQLDRSIPVQILNVMNDQSLAPYASDLLETMFTNHKVQFTSGSQKSTWIDQWHDVWVSPLLQILCEGNHDQTTYIIDYYLPKLLRCSPDSLSYMIRILQASADANLGSWSTRGALGALMACLRTARAHGHLELSNIMSRGLVSTESIKQGLVHQHNQVCIDALGLLCETHRSTEIVSVEEMQLILFFITYNLNSQSPSVRQQICSLLRKLFCRIRESSQVLYKWEQNKTKQELFEDSPKRNPLGILQKYQDFLSSLCDRLFEALFPGSSHPTRFSALSILGSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFSLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQIVARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKMDLLKMTIKELMSLASPSSEPPSAIPQVHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHPSLFLLLLILGKLYPSPMDGTYSALSMAPFVPFIIRCGHSPVYRSREMSGRALVPFVMINEVPHTVLSLLKGLPDSTSLCIRQNNIHGTLLQVSHLLQSYLDSKQLGNSDFEQGLSDIVTCIGSKLWLAKRPNPCLVTRAAFLDVLVMLSTHLGNSQKQGMQFVEFWEEMNRVISECELMTGIPYLTAVPGLVQYLQSITKLVISVLSVTSAADIQSSSSPTAMKIAKPPLSIVHLLHSEFHEVRLLALEAVLLWLKKVNAKQIAKEGGVLCLLVDLEGVLLSMTLKEKNLECFYKVLEILYNMDLRNVLPKIECSIKMNPNEFLTWSLDIMDNSNSTEVRSMALKFASKFVVHLLENHQQISEEVLKKWVQQLIYFCGDEQETEMLLAAAEVFRSITSLLLISEKLVLGLSDTLAMWKCVILLLQNEDLVVRDAAAEVLQVAQAEKKSSKGAGFMFRVMNAPLALDLAFGTLCEQLQQWGQTCAGIPVLLEWLLGDSDPRGGLEPSAPEEDECLFDKGEVNFWAEKLTSARLLALPPSPEFLKTAEFTKLAIQNEQISLCLKILNLLQSVGKGKDGNLKE", "length": 1890, "header": "tr|A0A8V0Z6Z3-1|A0A8V0ZE55_CHICK Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Gallus gallus OX=9031 GN=THADA PE=3 SV=1 CANONICAL=A0A8V0ZE55-1" }, "locus": { "chromosome": "3", "start_pos": 24823858, "end_pos": 24673160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049054.1", "url": "https://www.ensembl.org/id/ENSGALT00010049054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029003.1", "url": "https://www.ensembl.org/id/ENSGALP00010029003.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55/entry#A0A8V0ZDQ9-1", "sequence": { "sequence": "MVLKKKKKEIQVDAFSLDCQQLEKLQGFSKAEEQNLASLLLHCAQLSNGIQQIQCIKQIMPLVKAMDQNSACDPMLKACLEILGETYFSLDVKNPLKKVLASSLNGLPEWFMTLAVQSFVCCLREELKTTDVYLYRKVLDNLASCMEDFNLGRASITNLFEEVLQFLQKALLDIQEENRSNNGNRIVQTRLMHDLLMAIKVAMMLVQKLQENIQGSLWKNHESFVWQSMCNLLKSSSDFLMDETLLQTVQTTSGLAFILFTKAMYEPAEELPSLVSDLLCGSRKLAGMPAWFVNNCGALCTEQLSDSVLLFLCHGALAMLDWKSGSMGENGEKLLLDIASVLLSLSSELKESSMATSLSRILAIWTNSALAALIPDSPNLKVKLNGNSEVVGKLLEYVYTHWEHPLDAVRHQSKLIFRNLLQIHRTIIAASDEKSDPFFARLTRRLLSLEWHVKGKYASLACLVECLGTENILQLDRSIPVQILNVMNDQSLAPYASDLLETMFTNHKVQFTSGSQKSTWIDQWHDVWVSPLLQILCEGNHDQTTYIIDYYLPKLLRCSPDSLSYMIRILQASADANLGSWSTRGALGALMACLRTARAHGHLELSNIMSRGLVSTESIKQGLVHQHNQVCIDALGLLCETHRSTEIVSVEEMQLILFFITYNLNSQSPSVRQQICSLLRKLFCRIRESSQVLYKWEQNKTKQELFEDSPKRNPLGILQKYQDFLSSLCDRLFEALFPGSSHPTRFSALSILGSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFSLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQIVARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKMDLLKMTIKELMSLASPSSEPPSAIPQVHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHPSLFLLLLILGKLYPSPMDGTYSALSMAPFVPFIIRCGHSPVYRSREMSGRALVPFVMINEVPHTVLSLLKGLPDSTSLCIRQNNIHGTLLQVSHLLQSYLDSKQLGNSDFEQGLSDIVTCIGSKLWLAKRPNPCLVTRAAFLDVLVMLSTHLGNSQKQGMQFVEFWEEMNRVISECELMTGIPYLTAVPGLVQYLQSITKLVISVLSVTSAADIQSSSSPTAMKIAKPPLSIVHLLHSEFHEVRLLALEAVLLWLKKVNAKQIAKEGGVLCLLVDLEGVLLSMTLKEKNLECFYKVLEILYNMDLRNVLPKIECSIKMNPNEFLTWSLDIMDNSNSTEVRSMALKFASKFVVHLLENHQQISEEVLKKWVQQLIYFCGDEQETEMLLAAAEVFRSITSLLLISEKLVLGLSDTLAMWKCVILLLQNEDLVVRDAAAEVLQVAQAEKKSSKGAGR", "length": 1764, "header": "tr|A0A8V0ZDQ9-1|A0A8V0ZDQ9_CHICK Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Gallus gallus OX=9031 GN=THADA PE=3 SV=1 CANONICAL=A0A8V0ZE55-1" }, "locus": { "chromosome": "3", "start_pos": 24823858, "end_pos": 24693608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049033.1", "url": "https://www.ensembl.org/id/ENSGALT00010049033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028987.1", "url": "https://www.ensembl.org/id/ENSGALP00010028987.1" } ] } }, { "isoform_ac": "A0A8V0ZE55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55/entry#A0A8V0ZE55-1", "sequence": { "sequence": "MVLKKKKKEIQVDAFSLDCQQLEKLQGFSKAEEQNLASLLLHCAQLSNGIQQIQCIKQIMPLVKAMDQNSACDPMLKACLEILGETYFSLDVKNPLKKVLASSLNGLPEWFMTLAVQSFVCCLREELKTTDVYLYRKVLDNLASCMEDFNLGMMNISNTLSSVLTCSALSNNGNRIVQTRLMHDLLMAIKVAMMLVQKLQENIQGSLWKNHESFVWQSMCNLLKSSSDFLMDETLLQTVQTTSGLAFILFTKAMYEPAEELPSLVSDLLCGSRKLAGMPAWFVNNCGALCTEQLSDSVLLFLCHGALAMLDWKSGSMGENGEKLLLDIASVLLSLSSELKESSMATSLSRILAIWTNSALAALIPDSPNLKVKLNGNSEVVGKLLEYVYTHWEHPLDAVRHQSKLIFRNLLQIHRTIIAASDEKSDPFFARLTRRLLSLEWHVKGKYASLACLVECLGTENILQLDRSIPVQILNVMNDQSLAPYASDLLETMFTNHKVQFTSGSQKSTWIDQWHDVWVSPLLQILCEGNHDQTTYIIDYYLPKLLRCSPDSLSYMIRILQASADANLGSWSTRGALGALMACLRTARAHGHLELSNIMSRGLVSTESIKQGLVHQHNQVCIDALGLLCETHRSTEIVSVEEMQLILFFITYNLNSQSPSVRQQICSLLRKLFCRIRESSQVLYKWEQNKTKQELFEDSPKRNPLGILQKYQDFLSSLCDRLFEALFPGSSHPTRFSALSILGSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFSLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQIVARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKMDLLKMTIKELMSLASPSSEPPSAIPQVHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHPSLFLLLLILGKLYPSPMDGTYSALSMAPFVPFIIRCGHSPVYRSREMSGRALVPFVMINEVPHTVLSLLKGLPDSTSLCIRQNNIHGTLLQVSHLLQSYLDSKQLGNSDFEQGLSDIVTCIGSKLWLAKRPNPCLVTRAAFLDVLVMLSTHLGNSQKQGMQFVEFWEEMNRVISECELMTGIPYLTAVPGLVQYLQSITKLVISVLSVTSAADIQSSSSPTAMKIAKPPLSIVHLLHSEFHEVRLLALEAVLLWLKKVNAKQIAKEGGVLCLLVDLEGVLLSMTLKEKNLECFYKVLEILYNMDLRNVLPKIECSIKMNPNEFLTWSLDIMDNSNSTEVRSMALKFASKFVVHLLENHQQISEEVLKKWVQQLIYFCGDEQETEMLLAAAEVFRSITSLLLISEKLVLGLSDTLAMWKCVILLLQNEDLVVRDAAAEVLQVAQAEKKSSKGAGFMFRVMNAPLALDLAFGTLCEQLQQWGQTCAGIPVLLEWLLGDSDPRGGLEPSAPEEDECLFDKGEVNFWAEKLTSARLLGKHLLLLAQATHLALPDGGELDRLCRRAQDQAQLTARLLTALPPSPEFLKTAEFTKLAIQNEQISLCLKILNLLQSVGKGKDGNLKE", "length": 1920, "header": "tr|A0A8V0ZE55-1|A0A8V0ZE55_CHICK Isoform 1 of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Gallus gallus OX=9031 GN=THADA PE=3 SV=1 CANONICAL=A0A8V0ZE55-1" }, "locus": { "chromosome": "3", "start_pos": 24823858, "end_pos": 24673160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049045.1", "url": "https://www.ensembl.org/id/ENSGALT00010049045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028996.1", "url": "https://www.ensembl.org/id/ENSGALP00010028996.1" } ] } }, { "isoform_ac": "A0A8V0ZK74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55/entry#A0A8V0ZK74-1", "sequence": { "sequence": "MVLKKKKKEIQVDAFSLDCQQLEKLQGFSKAEEQNLASLLLHCAQLSNGIQQIQCIKQIMPLVKAMDQNSACDPMLKACLEILGETYFSLDVKNPLKKVLASSLNGLPEWFMTLAVQSFVCCLREELKTTDVYLYRKVLDNLASCMEDFNLVLQFLQKALLDIQEENRSNNGNRIVQTRLMHDLLMAIKVAMMLVQKLQENIQGSLWKNHESFVWQSMCNLLKSSSDFLMDETLLQTVQTTSGLAFILFTKAMYEPAEELPSLVSDLLCGSRKLAGMPAWFVNNCGALCTEQLSDSVLLFLCHGALAMLDWKSGSMGENGEKLLLDIASVLLSLSSELKESSMATSLSRILAIWTNSALAALIPDSPNLKVKLNGNSEVVGKLLEYVYTHWEHPLDAVRHQSKLIFRNLLQIHRTIIAASDEKSDPFFARLTRRLLSLEWHVKGKYASLACLVECLGTENILQLDRSIPVQILNVMNDQSLAPYASDLLETMFTNHKVQFTSGSQKSTWIDQWHDVWVSPLLQILCEGNHDQTTYIIDYYLPKLLRCSPDSLSYMIRILQASADANLGSWSTRGALGALMACLRTARAHGHLELSNIMSRGLVSTESIKQGLVHQHNQVCIDALGLLCETHRSTEIVSVEEMQLILFFITYNLNSQSPSVRQQICSLLRKLFCRIRESSQVLYKWEQNKTKQELFEDSPKRNPLGILQKYQDFLSSLCDRLFEALFPGSSHPTRFSALSILGSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFSLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQIVARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKMDLLKMTIKELMSLASPSSEPPSAIPQVHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHPSLFLLLLILGKLYPSPMDGTYSALSMAPFVPFIIRCGHSPVYRSREMSGRALVPFVMINEVPHTVLSLLKGLPDSTSLCIRQNNIHGTLLQVSHLLQSYLDSKQLGNSDFEQGLSDIVTCIGSKLWLAKRPNPCLVTRAAFLDVLVMLSTHLGNSQKQGMQFVEFWEEMNRVISECELMTGIPYLTAVPGLVQYLQSITKLVISVLSVTSAADIQSSSSPTAMKIAKPPLSIVHLLHSEFHEVRLLALEAVLLWLKKVNAKQIAKEGGVLCLLVDLEGVLLSMTLKEKNLECFYKVLEILYNMDLRNVLPKIECSIKMNPNEFLTWSLDIMDNSNSTEVRSMALKFASKFVVHLLENHQQISEEVLKKWVQQLIYFCGDEQETEMLLAAAEVFRSITSLLLISEKLVLGLSDTLAMWKCVILLLQNEDLVVRDAAAEVLQVAQAEKKSSKGAGFMFRVMNAPLALDLAFGTLCEQLQQWGQTCAGIPVLLEWLLGDSDPRGGLEPSAPEEDECLFDKGEVNFWAEKLTSARLLGKHLLLLAQATHLALPDGGELDRLCRRAQDQAQLTARLLTALPPSPEFLKTAEFTKLAIQNEQISLCLKILNLLQSVGKGKDGNLKE", "length": 1919, "header": "tr|A0A8V0ZK74-1|A0A8V0ZK74_CHICK Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Gallus gallus OX=9031 GN=THADA PE=3 SV=1 CANONICAL=A0A8V0ZE55-1" }, "locus": { "chromosome": "3", "start_pos": 24823858, "end_pos": 24673160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049050.1", "url": "https://www.ensembl.org/id/ENSGALT00010049050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028999.1", "url": "https://www.ensembl.org/id/ENSGALP00010028999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "pmid": "" }, { "name": "tRNA nucleoside ribose methylation", "id": "GO:0002128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002128", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum calcium ion concentration", "id": "GO:0032471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1635, "end_pos": 1637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE55" }, { "id": "PF10350", "database": "Pfam", "url": 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factor 5 OS=Gallus gallus OX=9031 GN=DCAF5 PE=4 SV=1 CANONICAL=A0A8V0ZEA0-1" }, "locus": { "chromosome": "5", "start_pos": 27710997, "end_pos": 27655838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049122.1", "url": "https://www.ensembl.org/id/ENSGALT00010049122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029039.1", "url": "https://www.ensembl.org/id/ENSGALP00010029039.1" } ] } }, { "isoform_ac": "A0A8V0ZE95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA0/entry#A0A8V0ZE95-1", "sequence": { "sequence": "MEEAIHSRVKPVQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESTETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESSHGEPFCLAHYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRRPQRIFSADVLACLVWPRSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHCRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPPDPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPDCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSAYSESESSASLHHSPPHVAEESAETAYNLRALRPAESPSGREDMASRQQRLSALRKYQDKRLLALSNESDSDDNTCEAELDTDLFPRPRSPSPEENESSSSSSSSSTEDEEELNERRTSMRQRNALRRRQKVQKEERTSTNTENVAPYIGEDIYDYPQIKVDDLSSSPASSPERNSANKEVLKERTSPCSDNESVERKIYKAYKWLHYSYISYSANKDGESSRGDAVNDEGRPGTSGRHNTAHSLNKEDARNLSSAVPQGSPVLSTESHNKETLKECGLIENPTNGQTHECDNQRRMEGQENVSEDTTSGGTERSFETKKLNGKANCKGLNSCTEEACIQTAGLVEQKNSQNCQPASSHHSLVPPFSAVAICSLSGHCSRNQTDDSEERSLDASCVNHNNGHLHLRPLCFSNGQSFGEQEAVIQGLQVHSNADNGNLEQMGVALHKDCCLSEMDSNSYNVSTREDTADLHPAGSESAQSRGGLKRHRVELEDADSEKSSLEKKLKT", "length": 893, "header": "tr|A0A8V0ZE95-1|A0A8V0ZE95_CHICK Computationally mapped isoform of DDB1 and CUL4 associated factor 5 OS=Gallus gallus OX=9031 GN=DCAF5 PE=4 SV=1 CANONICAL=A0A8V0ZEA0-1" }, "locus": { "chromosome": "5", "start_pos": 27710997, "end_pos": 27655838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049120.1", "url": "https://www.ensembl.org/id/ENSGALT00010049120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029037.1", "url": "https://www.ensembl.org/id/ENSGALP00010029037.1" } ] } }, { "isoform_ac": "A0A8V0ZEA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA0/entry#A0A8V0ZEA0-1", "sequence": { "sequence": "MGFPHKNTGGDDRRVLLWHMEEAIHSRVKPVQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESTETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESSHGEPFCLAHYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRRPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHCRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPPDPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPDCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSAYSESESSASLHHSPPHVAEESAETAYNLRALRPAESPSGREDMASRQQRLSALRKYQDKRLLALSNESDSDDNTCEAELDTDLFPRPRSPSPEENESSSSSSSSSTEDEEELNERRTSMRQRNALRRRQKVQKEERTSTNTENVAPYIGEDIYDYPQIKVDDLSSSPASSPERNSANKEVLKERTSPCSDNESVERKIYKAYKWLHYSYISYSANKDGESSRGDAVNDEGRPGTSGRHNTAHSLNKEDARNLSSAVPQGSPVLSTESHNKETLKECGLIENPTNGQTHECDNQRRMEGQENVSEDTTSGGTERSFETKKLNGKANCKGLNSCTEEACIQTAGLVEQKNSQNCQPASSHHSLVPPFSAVAICSLSGHCSRNQTDDSEERSLDASCVNHNNGHLHLRPLCFSNGQSFGEQEAVIQGLQVHSNADNGNLEQMGVALHKDCCLSEMDSNSYNVSTREDTADLHPAGSESAQSRGGLKRHRVELEDADSEKSSLEKKLKT", "length": 897, "header": "tr|A0A8V0ZEA0-1|A0A8V0ZEA0_CHICK Isoform 1 of DDB1- and CUL4-associated factor 5 OS=Gallus gallus OX=9031 GN=DCAF5 PE=4 SV=1 CANONICAL=A0A8V0ZEA0-1" }, "locus": { "chromosome": "5", "start_pos": 27710997, "end_pos": 27643906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049125.1", "url": "https://www.ensembl.org/id/ENSGALT00010049125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029042.1", "url": "https://www.ensembl.org/id/ENSGALP00010029042.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEA0", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 850, "end_pos": 852 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD17-1", "uniprot_ac": "A0A8V0ZD17", "uniprot_id": "A0A8V0ZD17_CHICK", "mass": { "chemical_mass": 45440.0, "monoisotopic_mass": 45440.0 }, "refseq": { "ac": "XP_004941333", "name": "bile acid-CoA:amino acid N-acyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941333" }, "gene_names": [ { "name": "BAAT", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ] }, { "name": "BAAT", "type": "synonym", "evidence": [ { "id": "XP_004941333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941333" } ] } ], "protein_names": [ { "name": "Bile acid-CoA:amino acid N-acyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17/entry#names_and_taxonomy" } ] }, { "name": "bile acid-CoA:amino acid N-acyltransferase", "type": "synonym", "evidence": [ { "id": "XP_004941333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941333.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941333" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BAAT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17", "locus": { "chromosome": "5", "start_pos": 223134, "end_pos": 217850, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020383", "url": "https://www.ensembl.org/id/ENSGALG00010020383" } ] } } ], "crossref": [ { "id": "A0A8V0ZD17", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD17", "database": "AlphaFoldDB", "categories": [] }, { "id": "769879", "url": "https://www.ncbi.nlm.nih.gov/gene/769879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769879", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769879", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISKPHAM", "url": "https://omabrowser.org/oma/group/ISKPHAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD17", "url": "https://www.orthodb.org/?gene=A0A8V0ZD17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-193368", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004941333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z793", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z793-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z793-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEVTVTPSSSLADQMVQVVVSGLAPSQLVTLRAWLMDEHGERFQARAFYRSDEEGTVDAGRHAALGGNYTGVWPMGLFWFLQPDSLFKRLVKRDVMGSPFLFHLEVFDGICLLSGQQDNPLATCTAERWYVGPGVQRVPIREGRVRGALLLPPGPGPFPAVIDLFGGAGGLIEFRAGLLASRGFAVLALAFFAYEDLPKGLTQLDLDYFEEAVELLLRHPKVRGPGLGVIGVSKGAEVALAMAAFLPQVVATVWINGTTFLYGNPLHYKGLRIPSIPYQTERMLFTELGAMDNSAIFADPRSPAYSSSAIPVEKIQGKVLFVVGEADRSFNSKLFAQLATERLPQDAYRLLSYPGAGHLIEPPGSPLCSISSLRGSPRPVVWGGEPVPHARAQQHSWQEIVQFLELHLNPVPAIKL", "length": 417, "header": "tr|A0A8V0ZD17-1|A0A8V0ZD17_CHICK Isoform 1 of Bile acid-CoA:amino acid N-acyltransferase OS=Gallus gallus OX=9031 GN=BAAT PE=1 SV=1 CANONICAL=A0A8V0ZD17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z793-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17/entry#A0A8V0Z793-1", "sequence": { "sequence": "MRAVRWDVISRRREEGAAWRMEGCDTAAAPGPEGPSGESSAPDLAQTSASGPVSEVPQAPARRKAVKKRKEAAVAAIPRGRPKSGRVWKDPGRKRFSLMVQDKPLRTSWERKLKERQEKKLVRDLVQQLQEAKQKEREEKKRRREENLRRRLENERKAEIVQVIRNPMKLKRAKKKQLRRVEKRDTLGMLQKAPVRCTMVEVTVTPSSSLADQMVQVVVSGLAPSQLVTLRAWLMDEHGERFQARAFYRSDEEGTVDAGRHAALGGNYTGVWPMGLFWFLQPDSLFKRLVKRDVMGSPFLFHLEVFDGICLLSGQQDNPLATCTAERWYVGPGVQRVPIREGRVRGALLLPPGPGPFPAVIDLFGGAGGLIEFRAGLLASRGFAVLALAFFAYEDLPKGLTQLDLDYFEEAVELLLRHPKVRGPGLGVIGVSKGAEVALAMAAFLPQVVATVWINGTTFLYGNPLHYKGLRIPSIPYQTERMLFTELGAMDNSAIFADPRSPAYSSSAIPVEKIQGKVLFVVGEADRSFNSKLFAQLATERLPQDAYRLLSYPGAGHLIEPPGSPLCSISSLRGSPRPVVWGGEPVPHARAQQHSWQEIVQFLELHLNPVPAIKL", "length": 615, "header": "tr|A0A8V0Z793-1|A0A8V0ZD17_CHICK Computationally mapped isoform of Bile acid-CoA:amino acid N-acyltransferase OS=Gallus gallus OX=9031 GN=BAAT PE=1 SV=1 CANONICAL=A0A8V0ZD17-1" }, "locus": { "chromosome": "5", "start_pos": 222940, "end_pos": 218049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049255.1", "url": "https://www.ensembl.org/id/ENSGALT00010049255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029117.1", "url": "https://www.ensembl.org/id/ENSGALP00010029117.1" } ] } }, { "isoform_ac": "A0A8V0ZD17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17/entry#A0A8V0ZD17-1", "sequence": { "sequence": "MVEVTVTPSSSLADQMVQVVVSGLAPSQLVTLRAWLMDEHGERFQARAFYRSDEEGTVDAGRHAALGGNYTGVWPMGLFWFLQPDSLFKRLVKRDVMGSPFLFHLEVFDGICLLSGQQDNPLATCTAERWYVGPGVQRVPIREGRVRGALLLPPGPGPFPAVIDLFGGAGGLIEFRAGLLASRGFAVLALAFFAYEDLPKGLTQLDLDYFEEAVELLLRHPKVRGPGLGVIGVSKGAEVALAMAAFLPQVVATVWINGTTFLYGNPLHYKGLRIPSIPYQTERMLFTELGAMDNSAIFADPRSPAYSSSAIPVEKIQGKVLFVVGEADRSFNSKLFAQLATERLPQDAYRLLSYPGAGHLIEPPGSPLCSISSLRGSPRPVVWGGEPVPHARAQQHSWQEIVQFLELHLNPVPAIKL", "length": 417, "header": "tr|A0A8V0ZD17-1|A0A8V0ZD17_CHICK Isoform 1 of Bile acid-CoA:amino acid N-acyltransferase OS=Gallus gallus OX=9031 GN=BAAT PE=1 SV=1 CANONICAL=A0A8V0ZD17-1" }, "locus": { "chromosome": "5", "start_pos": 222940, "end_pos": 220847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049251.1", "url": "https://www.ensembl.org/id/ENSGALT00010049251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029114.1", "url": "https://www.ensembl.org/id/ENSGALP00010029114.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769879", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769879", "resource": "KEGG Pathway" }, { "id": "R-GGA-159418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "resource": "Reactome", "description": "Recycling of bile acids and salts" }, { "id": "R-GGA-193368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALR5-1", "protein_name": "Bile acid-CoA:amino acid N-acyltransferase", "gene_name": "BAAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIQLTATPLSALDDEPMHIRFTGLTPFQIVFLQASLEDERRNMFHSYVYYKANEVGEVNLKQAASLGGDYVGVQPMGLFWSLKSEKVGIKLFKRDVMNSPFQVQLKLCDPAVLLTHIVSTPPIVCLTLERWYVAPGVTRTQGKEGHIRGVLFIPPREGHFPGVIDLFGILSGLMESWASLLASRGSAALALAYCNYEDLPPKLEKLDLEYFEEAVNFLLRHPKILGPGIGIVSISRGAEIGLSMAIHLKQVTATVLINGPNFIIDVPHVYHDQISQTLGFSPQYSSISNLGFIKLQNIFEENKNNANKAAFLPIEKAQGFPFIVGEEDKNVNSKAHAQQATERLKRHGKKNWTLQSYPGAGHLIEPPHSPLCCGSNVPSFHIAMYWRGEVIPHGATQEHSWKEIQKFLRKHLIPVVTSRF", "length": 420 }, "evidence": [ { "id": "A0A8V0ZD17", "url": "https://omabrowser.org/oma/group/A0A8V0ZD17/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14032-1", "protein_name": "Bile acid-CoA:amino acid N-acyltransferase", "gene_name": "BAAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL", "length": 418 }, "evidence": [ { "id": "A0A8V0ZD17", "url": "https://omabrowser.org/oma/group/A0A8V0ZD17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63276-1", "protein_name": "Bile acid-CoA:amino acid N-acyltransferase", "gene_name": "Baat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLTAVPLSALVDEPVHIRVTGLTPFQVVCLQASLKDDKGNLFNSQAFYRASEVGEVDLERDSSLGGDYMGVHPMGLFWSMKPEKLLTRLVKRDVMNRPHKVHIKLCHPYFPVEGKVISSSLDSLILERWYVAPGVTRIHVKEGRIRGALFLPPGEGPFPGVIDLFGGAGGLFEFRASLLASHGFATLALAYWGYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQITATVLINGPNFVSSNPHVYRGKVFQPTPCSEEFVTTNALGLVEFYRTFEETADKDSKYCFPIEKAHGHFLFVVGEDDKNLNSKVHAKQAIAQLMKSGKKNWTLLSYPGAGHLIEPPYSPLCSASRMPFVIPSINWGGEVIPHAAAQEHSWKEIQKFLKQHLNPGFNSQL", "length": 420 }, "evidence": [ { "id": "A0A8V0ZD17", "url": "https://omabrowser.org/oma/group/A0A8V0ZD17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91X34-1", "protein_name": "Bile acid-CoA:amino acid N-acyltransferase", "gene_name": "Baat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLTAVPLSALVDEPVHIQVTGLAPFQVVCLQASLKDEKGNLFSSQAFYRASEVGEVDLEHDPSLGGDYMGVHPMGLFWSLKPEKLLGRLIKRDVMNSPYQIHIKACHPYFPLQDIVVSPPLDSLTLERWYVAPGVKRIQVKESRIRGALFLPPGEGPFPGVIDLFGGAGGLMEFRASLLASRGFATLALAYWNYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQIRATVLINGPNFVSQSPHVYHGQVYPPVPSNEEFVVTNALGLVEFYRTFQETADKDSKYCFPIEKAHGHFLFVVGEDDKNLNSKVHANQAIAQLMKNGKKNWTLLSYPGAGHLIEPPYTPLCQASRMPILIPSLSWGGEVIPHAAAQEHSWKEIQKFLKQHLLPDLSSQL", "length": 420 }, "evidence": [ { "id": "A0A8V0ZD17", "url": "https://omabrowser.org/oma/group/A0A8V0ZD17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "bile acid conjugation", "id": "GO:0002152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002152", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "glycine metabolic process", "id": "GO:0006544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "taurine metabolic process", "id": "GO:0019530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019530", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "medium-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "N-acyltransferase activity", "id": "GO:0016410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "glycine N-choloyltransferase activity", "id": "GO:0047963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "very long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" }, { "name": "thiolester hydrolase activity", "id": "GO:0016790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" }, { "id": "PF04775", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 143, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZD17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD17" }, { "id": "PF08840", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAAT/Acyl-CoA thioester hydrolase C-terminal", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 410, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD27-1", "uniprot_ac": "A0A8V0ZD27", "uniprot_id": "A0A8V0ZD27_CHICK", "mass": { "chemical_mass": 84725.0, "monoisotopic_mass": 84725.0 }, "refseq": { "ac": "XP_004943008", "name": "solute carrier family 12 member 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943008" }, "gene_names": [ { "name": "SLC12A8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ] }, { "name": "SLC12A8", "type": "synonym", "evidence": [ { "id": "XP_004943008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943008" } ] } ], "protein_names": [ { "name": "Solute carrier family 12 member 8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 12 member 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943008" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943008.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943008" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC12A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27", "locus": { "chromosome": "7", "start_pos": 27604713, "end_pos": 27648460, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020385", "url": "https://www.ensembl.org/id/ENSGALG00010020385" } ] } } ], "crossref": [ { "id": "A0A8V0ZD27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD27", "database": "AlphaFoldDB", "categories": [] }, { "id": "424258", "url": "https://www.ncbi.nlm.nih.gov/gene/424258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424258", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMFIIQW", "url": "https://omabrowser.org/oma/group/IMFIIQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7A2", "url": "https://www.orthodb.org/?gene=A0A8V0Z7A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD27", "url": "https://www.orthodb.org/?gene=A0A8V0ZD27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD80", "url": "https://www.orthodb.org/?gene=A0A8V0ZD80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEK1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEM9", "url": "https://www.orthodb.org/?gene=A0A8V0ZEM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943008", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIPHGARGEGHVQELFHEEAQQGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVPEAGINDSRGSPVVEQSLIVEGSVQPQDEAALLQRASIASVNSAISYINYVIKGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPEHGFVGYSEELLFNNTLPDYSQGESFFTVFGVFFPAATGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 774, "header": "tr|A0A8V0ZD27-1|A0A8V0ZD27_CHICK Isoform 1 of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#A0A8V0Z7A2-1", "sequence": { "sequence": "MNIPHGARGEGHVQELFHEEAQQGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 683, "header": "tr|A0A8V0Z7A2-1|A0A8V0ZD27_CHICK Computationally mapped isoform of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "locus": { "chromosome": "7", "start_pos": 27646483, "end_pos": 27605448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049278.1", "url": "https://www.ensembl.org/id/ENSGALT00010049278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029127.1", "url": "https://www.ensembl.org/id/ENSGALP00010029127.1" } ] } }, { "isoform_ac": "A0A8V0ZD27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#A0A8V0ZD27-1", "sequence": { "sequence": "MNIPHGARGEGHVQELFHEEAQQGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVPEAGINDSRGSPVVEQSLIVEGSVQPQDEAALLQRASIASVNSAISYINYVIKGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPEHGFVGYSEELLFNNTLPDYSQGESFFTVFGVFFPAATGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 774, "header": "tr|A0A8V0ZD27-1|A0A8V0ZD27_CHICK Isoform 1 of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "locus": { "chromosome": "7", "start_pos": 27646483, "end_pos": 27605448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049272.1", "url": "https://www.ensembl.org/id/ENSGALT00010049272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029124.1", "url": "https://www.ensembl.org/id/ENSGALP00010029124.1" } ] } }, { "isoform_ac": "A0A8V0ZD80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#A0A8V0ZD80-1", "sequence": { "sequence": "MNIPHGARGEGHVQELFHEEAQQGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPEHGFVGYSEELLFNNTLPDYSQGESFFTVFGVFFPAATGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 721, "header": "tr|A0A8V0ZD80-1|A0A8V0ZD80_CHICK Computationally mapped isoform of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "locus": { "chromosome": "7", "start_pos": 27646483, "end_pos": 27605448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049359.1", "url": "https://www.ensembl.org/id/ENSGALT00010049359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029176.1", "url": "https://www.ensembl.org/id/ENSGALP00010029176.1" } ] } }, { "isoform_ac": "A0A8V0ZEK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#A0A8V0ZEK1-1", "sequence": { "sequence": "MNIPHGARGEGHVQELFHEEAQQGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPEHGFVGYSEELLFNNTLPDYSQGESFFTVFGVFFPAATGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEGEDRVHRNESQEKFQCNFLWKINHRKAESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 748, "header": "tr|A0A8V0ZEK1-1|A0A8V0ZEK1_CHICK Computationally mapped isoform of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "locus": { "chromosome": "7", "start_pos": 27646483, "end_pos": 27605448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049301.1", "url": "https://www.ensembl.org/id/ENSGALT00010049301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029150.1", "url": "https://www.ensembl.org/id/ENSGALP00010029150.1" } ] } }, { "isoform_ac": "A0A8V0ZEM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27/entry#A0A8V0ZEM9-1", "sequence": { "sequence": "MVPEGSQTQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVVMGMFLVSFVVLVALVTVLSGIGVCEKCSIGSGGVYSMISTVLGGQVGGTIGLLYIFGQCVAGAMYITGFAESIADVLNLSNIWAVRGISLAVLLGLLGINLAGVKWIIRLQLLLLFLLAVSTLDFVIGSFSHLDPEHGFVGYSEELLFNNTLPDYSQGESFFTVFGVFFPAATGVMAGFNMSGDLQKPATNIPLGSLAAIGTSWFLYMVFVFLLGAICTRQSLRYDFMIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQENVVPMLTFLGRGKGPNKTPVAAICLTSLITMAFVFIGQVNVLAPIVTINFMLTYIAVDYSYFSISLSYDVQQRPGKILVENTKPPHSSQPLIFNRPSSHASDGVIQSTSNGTLLEFRKDMDQLFKPFHNEPGAGKKEGAENLMQKVKQKKAKKPAKQMLQDSFLLDLDHDAPPARHGWDETTEPPPKSQQCEVGPCWSPPAVDHQGPPEHGEQLYSKAPEVLGRGIEESSTRQQNPELEIQQIQKSFYSKFCNYWVSFAGAIVSLVIMFVIQWIYTLVSLGAAVVLYFYIGQVSPGLPLGAAANFSLFSWIKSVLTTSCRRRPSPKEQIVVTPAFATVGMETRQLTEENEDFASRDRYHQSSLISREEFGNQFQ", "length": 702, "header": "tr|A0A8V0ZEM9-1|A0A8V0ZEM9_CHICK Computationally mapped isoform of Solute carrier family 12 member 8 OS=Gallus gallus OX=9031 GN=SLC12A8 PE=3 SV=1 CANONICAL=A0A8V0ZD27-1" }, "locus": { "chromosome": "7", "start_pos": 27646470, "end_pos": 27605448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049366.1", "url": "https://www.ensembl.org/id/ENSGALT00010049366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029182.1", "url": "https://www.ensembl.org/id/ENSGALP00010029182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424258", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BF89-1", "protein_name": "Solute carrier family 12 member 8", "gene_name": "slc12a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPQVQELFHEDAQGSQINAQPWWKVQLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVFLGMLLVSLVVLVALVTVMSGVGVSECCSVGNGGVYSMISTVLGGRIGGTVGLLYVFGQCVAGAMYITGFAESIAQVLSLQSTWVVRGISVAVLLGLLGINLAGVKWIVRLQLVLLGILAMSTLDFVIGTFSHLDPEHGFVGYSEKLLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQRPEHNIPVGTLAAVCTSWFLYLVFVFLLGAICTREALRYDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPVLAFLGKGRGPNKTPVAAICLTSLITMGFIFIGQVNVLAPIVTINFMLTYSVIDYCYFCVVKTYELQVQQRKKLISRSSSRKSLVSSTHPRYGSGGAISDPVNGTLLQFTKDMDQIFPLPSTEEQRASPASKARGRKTKIPAKEMLMNSFGLDLNSNAPLDKGKDERELEQAAGLDDDTSSQIGLIESDLKMGNQMNLSLPNSGPAELEQLPKEKIDRNGSETNLEGSEIRSIQSSVYARFCNPWVSLIGALCSFMIMFIIQWMYALINISAALILFIYIGTTSPGLPTGAASHFSFFKWLKTSLHNLGRQNGALQDQIVVTPSLSAVGMETRQLTEENADFALRDRYHHSSFITTTDKMVHPQSN", "length": 708 }, "evidence": [ { "id": "A0A8V0ZD27", "url": "https://omabrowser.org/oma/group/A0A8V0ZD27/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AV02-1", "protein_name": "Solute carrier family 12 member 8", "gene_name": "SLC12A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQMSQVQELFHEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLREGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKSKKATKQTLQDSFLLDLKSPPSFPVEISDRLPAASWEGQESCWNKQTSKSEGTQPEGTYGEQLVPELCNQSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSCRSLRSPQEQIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLMPHY", "length": 714 }, "evidence": [ { "id": "A0A8V0ZD27", "url": "https://omabrowser.org/oma/group/A0A8V0ZD27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O46100-1", "protein_name": "Solute carrier family 12 member 8", "gene_name": "EG:8D8.3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTNSSEGNGNGGRRTVDWQRFGLGGDEDGDVAVTSFRQRTNNNTGGFVDLGNEYTYAAGGHHASGANEIFAGEQGDKPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEASGGFNGWASGNFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAWLKSVIFRCFGKRMNEYEQIVVTPSCPGVDLSPTQLNEQNEDFRPRPNYHHSSVIEGRLIDDI", "length": 712 }, "evidence": [ { "id": "A0A8V0ZD27", "url": "https://omabrowser.org/oma/group/A0A8V0ZD27/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CJI3-1", "protein_name": "Solute carrier family 12 member 8", "gene_name": "Slc12a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQRSPQELFHEAAQQGVLARSQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVILVALITVLSGIGVAEHGWMGSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYLTGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLSLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPADQHTPRLPSSCWVSRGFSNIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLGNGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIAVDYSYFALSMAHCGLAQSPEPMPRQGPDALHCSEHLLQDKAPSYGSDTPAGSLSEGTLLEFTKDMDQLLQPIGGLESQPRSREVNQVLKSQKHKCKKDAKQTLQDSFLLDAESPLSFSMGASERLSVASCGEQESYQNQQTSRSESHDHLVPDLCTQPRANGEDFFLKCRLQEQQVQRRPSAFYVCMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYLYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSTREQIILAPSPAKVDMAMTQAYPGQWQTSATRERYHRSSFLSREQLMPPY", "length": 707 }, "evidence": [ { "id": "A0A8V0ZD27", "url": "https://omabrowser.org/oma/group/A0A8V0ZD27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VI23-1", "protein_name": "Solute carrier family 12 member 8", "gene_name": "Slc12a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQRSPQELFHEAAQQGILAQPQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLANGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLGSREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRNQPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQLTQDNADFATRDRYHHSSFLSREQLMPPY", "length": 705 }, "evidence": [ { "id": "A0A8V0ZD27", "url": "https://omabrowser.org/oma/group/A0A8V0ZD27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chloride:monoatomic cation symporter activity", "id": "GO:0015377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015377", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "potassium:chloride symporter activity", "id": "GO:0015379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD27" }, { "id": "PF00324", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid permease/ SLC12A", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 456, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0ZDC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1", "locus": { "chromosome": "22", "start_pos": 2980691, "end_pos": 2978814, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020450", "url": "https://www.ensembl.org/id/ENSGALG00010020450" } ] } } ], "crossref": [ { "id": "A0A8V0ZDC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7J0", "url": "https://www.orthodb.org/?gene=A0A8V0Z7J0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7J0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGDRLSLGSSRSHSAPFGHPSTPFVPTRLLSAAPRLHSATPRLPSFPLGSLRLSLGSFRFPSTHFVLSRLPSAPPVPTRLPSALPAPLMAAGRRSPPGPCCPPRVAVPSVHQSLPEMDFERGIWAAARDGDEARVLQLLERRGEPSQPDLAGYTALHYASRNGHLGVCRLLLQRGAHCNARTPGGATALHRACYCGHVAVARLLLAHGADPAAADGDGRTSLHKVRGGSEGAARPFWDAPPYRGGGGIPTVGRTQAAERGHRELCVLLLQNSPALLAARDAKGRRPRDTADPAVWDLLEG", "length": 302, "header": "tr|A0A8V0ZDC1-1|A0A8V0ZDC1_CHICK Isoform 1 of Ankyrin repeat domain 39 OS=Gallus gallus OX=9031 GN=ANKRD39 PE=4 SV=1 CANONICAL=A0A8V0ZDC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7J0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1/entry#A0A8V0Z7J0-1", "sequence": { "sequence": "MRLGDRLSLGSSRSHSAPFGHPSTPFVPTRLLSAAPRLHSATPRLPSFPLGSLRLSLGSFRFPSTHFVLSRLPSAPPVPTRLPSALPAPLMAAGRRSPPGPCCPPRVAVPSVHQSLPEMDFERGIWAAARDGDEARVLQLLERRGEPSQPDLAGYTALHYASRNGHLGVCRLLLQRGAHCNARTPGGATALHRACYCGHVAVARLLLAHGADPAAADGDGRTSLHKAAERGHRELCVLLLQNSPALLAARDAKGRRPRDTADPAVWDLLEG", "length": 271, "header": "tr|A0A8V0Z7J0-1|A0A8V0ZDC1_CHICK Computationally mapped isoform of Ankyrin repeat domain 39 OS=Gallus gallus OX=9031 GN=ANKRD39 PE=4 SV=1 CANONICAL=A0A8V0ZDC1-1" }, "locus": { "chromosome": "22", "start_pos": 2980005, "end_pos": 2978926, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049431.1", "url": "https://www.ensembl.org/id/ENSGALT00010049431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029214.1", "url": "https://www.ensembl.org/id/ENSGALP00010029214.1" } ] } }, { "isoform_ac": "A0A8V0ZDC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1/entry#A0A8V0ZDC1-1", "sequence": { "sequence": "MRLGDRLSLGSSRSHSAPFGHPSTPFVPTRLLSAAPRLHSATPRLPSFPLGSLRLSLGSFRFPSTHFVLSRLPSAPPVPTRLPSALPAPLMAAGRRSPPGPCCPPRVAVPSVHQSLPEMDFERGIWAAARDGDEARVLQLLERRGEPSQPDLAGYTALHYASRNGHLGVCRLLLQRGAHCNARTPGGATALHRACYCGHVAVARLLLAHGADPAAADGDGRTSLHKVRGGSEGAARPFWDAPPYRGGGGIPTVGRTQAAERGHRELCVLLLQNSPALLAARDAKGRRPRDTADPAVWDLLEG", "length": 302, "header": "tr|A0A8V0ZDC1-1|A0A8V0ZDC1_CHICK Isoform 1 of Ankyrin repeat domain 39 OS=Gallus gallus OX=9031 GN=ANKRD39 PE=4 SV=1 CANONICAL=A0A8V0ZDC1-1" }, "locus": { "chromosome": "22", "start_pos": 2980005, "end_pos": 2978926, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049434.1", "url": "https://www.ensembl.org/id/ENSGALT00010049434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029216.1", "url": "https://www.ensembl.org/id/ENSGALP00010029216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEF4-1", "uniprot_ac": "A0A8V0ZEF4", "uniprot_id": "A0A8V0ZEF4_CHICK", "mass": { "chemical_mass": 88848.0, "monoisotopic_mass": 88848.0 }, "refseq": { "ac": "NP_001186370", "name": "cysteine-rich protein 2-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" }, "gene_names": [ { "name": "KAT14", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ] }, { "name": "CSRP2BP", "type": "synonym", "evidence": [ { "id": "NP_001186370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" } ] }, { "name": "KAT14", "type": "synonym", "evidence": [ { "id": "NP_001186370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" } ] } ], "protein_names": [ { "name": "Cysteine-rich protein 2-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#names_and_taxonomy" } ] }, { "name": "ADA2A-containing complex subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#names_and_taxonomy" } ] }, { "name": "CRP2-binding partner", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#names_and_taxonomy" } ] }, { "name": "CSRP2 binding protein", "type": "synonym", "evidence": [ { "id": "NP_001186370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" } ] }, { "name": "Lysine acetyltransferase 14", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#names_and_taxonomy" } ] }, { "name": "cysteine-rich protein 2-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001186370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.68621.1, SRR13267656.11864.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001186370.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370" } ] }, { "annotation": "Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K3#function" }, { "database": "UniProtKB", "id": "ARBA00053435", "url": "https://www.uniprot.org/uniprotkb/ARBA00053435#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KAT14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4", "locus": { "chromosome": "3", "start_pos": 15108474, "end_pos": 15137045, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018631", "url": "https://www.ensembl.org/id/ENSGALG00010018631" } ] } } ], "crossref": [ { "id": "A0A8V0ZEF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416721", "url": "https://www.ncbi.nlm.nih.gov/gene/416721", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416721", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416721", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRRNWPW", "url": "https://omabrowser.org/oma/group/PRRNWPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7K3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZEF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20916:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20916:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186370", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANNVHMSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDASWMEEMSYYCEKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQFERLRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPLYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASALKAKAASKPPLDPIITVEGLRKRVSRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFSSRGRRPDIVLEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEEMEGDGVIDPGIEYVPTPSGTAGAGTMIASRKKVKTAEQIKQEVESEEEKTERMEGDSEDPEESNTSLQLRGRDKRKPQLEKDAKPRAPKHTSVSIYEEKLLLKRLEACPNALSMTPEARRLRRKLIVRQAKRERGLPLFDLDQVVNAALLLVDGIYGAKEGVSRSPVGQATYRTTSQDFRILDRYQTVLPAMKGYRQQTTKFLYRLVGSEDLLPDHSIVSPYTSRVLKPYIRRDYETKPPKLRLLAEIWAYPHRNDLNWKAEPEAPIDYCYVRPNHIPTINSMCHEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYILDFYDKYYPLDSKECKHAFFLRLRR", "length": 781, "header": "tr|A0A8V0ZEF4-1|A0A8V0ZEF4_CHICK Isoform 1 of Cysteine-rich protein 2-binding protein OS=Gallus gallus OX=9031 GN=KAT14 PE=4 SV=1 CANONICAL=A0A8V0ZEF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#A0A8V0Z7K3-1", "sequence": { "sequence": "MANNVHMSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDASWMEEMSYYCEKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQFERLRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPLYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASALKAKASKPPLDPIITVEGLRKRVSRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFSSRGRRPDIVLEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEEMEGDGVIDPGIEYVPTPSGTAGAGTMIASRKKVKTAEQIKQEVESEEEKTERMEGDSEDPEESNTSLQLRGRDKRKPQLEKDAKPRAPKHTSVSIYEEKLLLKRLEACPNALSMTPEARRLRRKLIVRQAKRERGLPLFDLDQVVNAALLLVDGIYGAKEGVSRSPVGQATYRTTSQDFRILDRYQTVLPAMKGYRQQTTKFLYRLVGSEDLLPDHSIVSPYTSRVLKPYIRRDYETKPPKLRLLAEIWAYPHRNDLNWKAEPEAPIDYCYVRPNHIPTINSMCHEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYILDFYDKYYPLDSKECKHAFFLRLRR", "length": 780, "header": "tr|A0A8V0Z7K3-1|A0A8V0ZEF4_CHICK Computationally mapped isoform of Cysteine-rich protein 2-binding protein OS=Gallus gallus OX=9031 GN=KAT14 PE=4 SV=1 CANONICAL=A0A8V0ZEF4-1" }, "locus": { "chromosome": "3", "start_pos": 15135391, "end_pos": 15118844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045074.1", "url": "https://www.ensembl.org/id/ENSGALT00010045074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026932.1", "url": "https://www.ensembl.org/id/ENSGALP00010026932.1" } ] } }, { "isoform_ac": "A0A8V0ZEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4/entry#A0A8V0ZEF4-1", "sequence": { "sequence": "MANNVHMSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDASWMEEMSYYCEKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQFERLRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPLYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASALKAKAASKPPLDPIITVEGLRKRVSRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFSSRGRRPDIVLEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEEMEGDGVIDPGIEYVPTPSGTAGAGTMIASRKKVKTAEQIKQEVESEEEKTERMEGDSEDPEESNTSLQLRGRDKRKPQLEKDAKPRAPKHTSVSIYEEKLLLKRLEACPNALSMTPEARRLRRKLIVRQAKRERGLPLFDLDQVVNAALLLVDGIYGAKEGVSRSPVGQATYRTTSQDFRILDRYQTVLPAMKGYRQQTTKFLYRLVGSEDLLPDHSIVSPYTSRVLKPYIRRDYETKPPKLRLLAEIWAYPHRNDLNWKAEPEAPIDYCYVRPNHIPTINSMCHEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYILDFYDKYYPLDSKECKHAFFLRLRR", "length": 781, "header": "tr|A0A8V0ZEF4-1|A0A8V0ZEF4_CHICK Isoform 1 of Cysteine-rich protein 2-binding protein OS=Gallus gallus OX=9031 GN=KAT14 PE=4 SV=1 CANONICAL=A0A8V0ZEF4-1" }, "locus": { "chromosome": "3", "start_pos": 15135391, "end_pos": 15118844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045071.1", "url": "https://www.ensembl.org/id/ENSGALT00010045071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026929.1", "url": "https://www.ensembl.org/id/ENSGALP00010026929.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416721", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416721", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSX8-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "Kat14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIHLSGLLSRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDISWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCADCSADGKEQSERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPVYFRSGAQEFGEPGWWKLVHNRPPTMRPEGEKLSASTLKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGLLDRSTSSTPVKFISRGRRPDMILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYIPPPAGSASGLMGSRKKVRAAEQIKQEVDSEEEKPDRMDGDSEDTDSNTSLHTRAREKRKPPLEKDTKPKGPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDEVVNAALLLVDGIYGAKDGGASRLPAGQATYRTTCQDFRILDRYQTALPARKGFRHQTTRFLYRLVGSEDLAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHKSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 779 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BE91-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGSIHLSGLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDHSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQYERLKLTWQQVVVLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHNRPPTLKPEGEKLSASALKVRASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFADRSSSSTPVKFISRGRRPDVILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDEMEGDGVIDPGMEYVPPPAGTAASGTGLGGRKKVRAPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQMRAREKRKPVLEKDRKPKGPKFTPVSIYEEKLLLRRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKDGGVSRLPAGQATYRTTCQDFRILDRYQTALPSRKGFRHQSTKFLYRLVGSEDTAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRGDPHWMPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGVDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPDWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 781 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SBH7-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METNIHLGSLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDMSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSEDGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHSRPPTLKPEGEKLATSALKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFVSRGRRPDMILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYVPPPACSSASGTGVGGRKKVRAPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQTRAREKRKQALEKDRKPKGPKFTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKDGGVSRLPAGQATYRTTCQDFRILDRYQTALPSRKGFRHQTSKFLYRLVGSEDMAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGVDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 781 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LXR5-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "kat14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSGDQRGLTVQDEETMCTSASEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDIGEDGEGSWNEDMSFYCDKCHKWIPAVQLRGEQPSYLKGDNFFKFICSDCAEDGKESFERMRLTWQQVVMLAMYNLSLEGTGRQGYFRWKEDICAFISRHWTFLLGSRKKTSTWWSTVAGCLSVGSPTFFRSGAQEFGEPGWWKLVQNRPPTLRPEGDKSSAASVKAKAVSKPSLDPIITVEGLRKRGSRNPVENAMQLKEKRSRTQEAKEIRRAQKEAAGFLDRSASSTPVKLGNRARRPEPYLEKGEVIDFSSLSSSDRTPLTSPSPSPSPDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDEELDAEGVIDPGMEYIPPPSMPLATGTIMVRKKLRPAELIKQELESEDEERGRDVEEDEGQDDGRRGRVLERRKGLQDKGEGCVSLPAPRHTFISLYEERMLLHKLEACPQALAVTPQAKRLHRKLLVRQAKRERGLPLLDVDQAVSATLSLVGGVYGAQGGLARHRTSGEEKYRTTSQDLRILDRFQSTVSVRKGFYQHTVSFWHRLMGSDACVDQTIKSPYTSRVLKPFIRRDYESRPLKLRLLSEIRAHHHRNDPNWVAEPDAPIDYCYVRPNHIPSVNSMCQDIFWPGIDLSECLQYPDFSVVVLYKKVVIGFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNSAMLLYQKFGFKTEEYILDFYDKYYPVDSKECRHAFLLRLRR", "length": 782 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CID0-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "Kat14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSIHLSGLLSRHDDDATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCCDCSADGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPVYFRSGAQEFGEPGWWKLVHNRPPTMRPEGEKLAASTLKVKASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGLLDRSTSSTPVKFISRGRRPDLILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDELEGDGVIDPGMEYIPPPAGSASGLLGSRKKVRAPEQIKQEVDSEEEKPDRMDGDSEDTDSNISLHTRAREKRKPPLEKDMKPKGPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDEVVNAALLLVDGIYGAKDGGASRLAAGQATYRTTCQDFRILDRYQTALPARKGFRHQTTRFLYRLVGSEDLAVDQSIISPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPGPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIVAFGFMVPDVKYNEAYISFLLVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 779 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8E8-1", "protein_name": "Cysteine-rich protein 2-binding protein", "gene_name": "KAT14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSIHLSSLISRHDDEATRTSTSEGLEEGEVEGETLLIVESEDQASVDLSHDQSGDSLNSDEGDVSWMEEQLSYFCDKCQKWIPASQLREQLSYLKGDNFFRFTCSDCSADGKEQYERLKLTWQQVVMLAMYNLSLEGSGRQGYFRWKEDICAFIEKHWTFLLGNRKKTSTWWSTVAGCLSVGSPMYFRSGAQEFGEPGWWKLVHNKPPTMKPEGEKLSASTLKIKAASKPTLDPIITVEGLRKRASRNPVESAMELKEKRSRTQEAKDIRRAQKEAAGFLDRSTSSTPVKFISRGRRPDVILEKGEVIDFSSLSSSDRTPLTSPSPSPSLDFSAPGTPASHSATPSLLSEADLIPDVMPPQALFHDDDEMEGDGVIDPGMEYVPPPAGSVASGPVVGVRKKVRGPEQIKQEVESEEEKPDRMDIDSEDTDSNTSLQTRAREKRKPQLEKDTKPKEPRYTPVSIYEEKLLLKRLEACPGAVAMTPEARRLKRKLIVRQAKRDRGLPLFDLDQVVNAALLLVDGIYGAKEGGISRLPAGQATYRTTCQDFRILDRYQTSLPSRKGFRHQTTKFLYRLVGSEDMAVDQSIVSPYTSRILKPYIRRDYETKPPKLQLLSQIRSHLHRSDPHWTPEPDAPLDYCYVRPNHIPTINSMCQEFFWPGIDLSECLQYPDFSVVVLYKKVIIAFGFMVPDVKYNEAYISFLFVHPEWRRAGIATFMIYHLIQTCMGKDVTLHVSASNPAMLLYQKFGFKTEEYVLDFYDKYYPLESTECKHAFFLRLRR", "length": 782 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJ73-1", "protein_name": "2.3.1.-", "gene_name": "Atac2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRPSNWDDPQGPCRYCESPVEDDNYLECQECRRMVHIKCLPHACTPGDLLGDVFFEFTCVKCVLDKAKESVIPSDLEPIKEVIVRQRIPWLLVLTLTLYNLSIKQKGLGHHGFFHWRTHIISFVDKNWNYIFGPNVRRRKQWTGSVSGALSHNSPEYFQSGLDVFQENGWWKLAKPFQTPRSVLKEYEKKQQLRLQMRIEKRLPAADETSCSSEISVADHAQDNPPLIKAEAEKPSSTEGCARTIPYMGRLPKIQTQPSPLSQETLPGPPILQENIAPPSQKEEEPQNQPMSMVQAGLMDFLAESLESDDFTMFGNLPGIMPPPLIGAGKNDFFMTEPLLHAPLNNEGLFDMDTNFAIPNTADETKPISTEEPAAESSEEQKEGEVEDEKPEEDESPDYQPRIVQVTNYQAQEANESIKEEPLEEIMQDDDVTTNSKSSILEPCKPSGFVRQPRRNWPWLQEAQDPDDMAIPSENLKLINAYEEQKLYQRLDRIFALEHQCHISIPAYVRRLYRKLSLRKWKRDHNRHIFNLDEHIDPLGRARLKMLGHQKAEILDRYQLLAHSRQDARSSFHARLAGCTQYELFESPYSQRVLHPFIFRSETMAPPWLKLMCELQHRVNGSHPTRSTIDFCFVRPQHIPAVNALLQSTFWPNIDVSECLSYPDYSVVALYKKLVIGCGFLVPDVGYNEAYISFMAVRPCWQRSGIASFMLYHLIQTCMSKDITLHVSATNAAVMLYQKFGFKMEEIILDFYDKYLPLDSKQSRNAFFLRLQR", "length": 774 }, "evidence": [ { "id": "A0A8V0ZEF4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEF4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" }, { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF4" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 637, "end_pos": 781, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 338, 345, 386 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 434, "end_pos": 436 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEG4-1", "uniprot_ac": "A0A8V0ZEG4", "uniprot_id": "A0A8V0ZEG4_CHICK", "mass": { "chemical_mass": 82955.0, "monoisotopic_mass": 82955.0 }, "refseq": {}, "gene_names": [ { "name": "SEC14L5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" } ] } ], "protein_names": [ { "name": "SEC14 like lipid binding 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC14L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4", "locus": { "chromosome": "14", "start_pos": 13371065, "end_pos": 13337986, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018638", "url": "https://www.ensembl.org/id/ENSGALG00010018638" } ] } } ], "crossref": [ { "id": "A0A8V0ZEG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7L3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZEG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23324:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23324:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQKYQSPVRVYKYPFELVMAVSKCSALLLLQLLRAAASGQWEAYEKRFPTCPEIPVFLGSEILHESKSDDGAIHIIERSCKLNVDAPRLLKKIAGVEYVFFIQKNTVNWKERTLRIEAHNETFANRVVVLETCSYSVHPENEEWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKRGKEVIEHYLKELISQGITFIPRWTPPVAHGQKAEQAPASSHDTNDAPLESGAHGATKEQTGSSCPPAEPVSPDADKLDADYIERYLGQLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREMLCQSLSWRKQYQVDYILQSWRPPALLDEYYTGGWHYQDRDGRPLYILRLGQMDTKGLVKALGEESLLRHVLSINEEGQKRCEENTNLFGRPITSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRQKFLIYSGNNYQGPGGLVDYVDKEVIPDFLGGDCMCTVPEGGLVPKSLYQTDEEPENADHIRLWTETIYHSASVLRGAPHEIVVEILEGESVITWDFDILKGDVVFSLFHSKRAPETGHKEATLPSSSAAGDNVQLIDKTWVLGVDYSRMESPLVCREGESIQGSHVTRWPGFYILQWKMHGPLPCSGSSLPRVDDVLASLQVSSHKCKLIYYYEVLASKDFRGSMSSLESCNSGFSQLSGVTTSSSQSQSSSHLSR", "length": 732, "header": "tr|A0A8V0ZEG4-1|A0A8V0ZEG4_CHICK Isoform 1 of SEC14 like lipid binding 5 OS=Gallus gallus OX=9031 GN=SEC14L5 PE=4 SV=1 CANONICAL=A0A8V0ZEG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4/entry#A0A8V0Z7L3-1", "sequence": { "sequence": "MVQKYQSPVRVYKYPFELVMAAYEKRFPTCPEIPVFLGSEILHESKSDDGAIHIIERSCKLNVDAPRLLKKIAGVEYVFFIQKNTVNWKERTLRIEAHNETFANRVVVLETCSYSGKEVIEHYLKELISQGITFIPRWTPPVAHGQKAEQAPASSHDTNDAPLESGAHGATKEQTGSSCPPAEPVSPDADKLDADYIERYLGQLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREMLCQSLSWRKQYQVDYILQSWRPPALLDEYYTGGWHYQDRDGRPLYILRLGQMDTKGLVKALGEESLLRHVLSINEEGQKRCEENTNLFGRPITSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRQKFLIYSGNNYQGPGGLVDYVDKEVIPDFLGGDCMCTVPEGGLVPKSLYQTDEEPENADHIRLWTETIYHSASVLRGAPHEIVVEILEGESVITWDFDILKGDVVFSLFHSKRAPETGHKEATLPSSSAAGDNVQLIDKTWVLGVDYSRMESPLVCREGESIQGSHVTRWPGFYILQWKMHGPLPCSGSSLPRVDDVLASLQVSSHKCKLIYYYEVLASKDFRGSMSSLESCNSGFSQLSGVTTSSSQSQSSSHLSR", "length": 667, "header": "tr|A0A8V0Z7L3-1|A0A8V0ZEG4_CHICK Computationally mapped isoform of SEC14 like lipid binding 5 OS=Gallus gallus OX=9031 GN=SEC14L5 PE=4 SV=1 CANONICAL=A0A8V0ZEG4-1" }, "locus": { "chromosome": "14", "start_pos": 13370071, "end_pos": 13342910, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045097.1", "url": "https://www.ensembl.org/id/ENSGALT00010045097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026942.1", "url": "https://www.ensembl.org/id/ENSGALP00010026942.1" } ] } }, { "isoform_ac": "A0A8V0ZEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4/entry#A0A8V0ZEG4-1", "sequence": { "sequence": "MVQKYQSPVRVYKYPFELVMAVSKCSALLLLQLLRAAASGQWEAYEKRFPTCPEIPVFLGSEILHESKSDDGAIHIIERSCKLNVDAPRLLKKIAGVEYVFFIQKNTVNWKERTLRIEAHNETFANRVVVLETCSYSVHPENEEWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKRGKEVIEHYLKELISQGITFIPRWTPPVAHGQKAEQAPASSHDTNDAPLESGAHGATKEQTGSSCPPAEPVSPDADKLDADYIERYLGQLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREMLCQSLSWRKQYQVDYILQSWRPPALLDEYYTGGWHYQDRDGRPLYILRLGQMDTKGLVKALGEESLLRHVLSINEEGQKRCEENTNLFGRPITSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRQKFLIYSGNNYQGPGGLVDYVDKEVIPDFLGGDCMCTVPEGGLVPKSLYQTDEEPENADHIRLWTETIYHSASVLRGAPHEIVVEILEGESVITWDFDILKGDVVFSLFHSKRAPETGHKEATLPSSSAAGDNVQLIDKTWVLGVDYSRMESPLVCREGESIQGSHVTRWPGFYILQWKMHGPLPCSGSSLPRVDDVLASLQVSSHKCKLIYYYEVLASKDFRGSMSSLESCNSGFSQLSGVTTSSSQSQSSSHLSR", "length": 732, "header": "tr|A0A8V0ZEG4-1|A0A8V0ZEG4_CHICK Isoform 1 of SEC14 like lipid binding 5 OS=Gallus gallus OX=9031 GN=SEC14L5 PE=4 SV=1 CANONICAL=A0A8V0ZEG4-1" }, "locus": { "chromosome": "14", "start_pos": 13370071, "end_pos": 13342910, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045092.1", "url": "https://www.ensembl.org/id/ENSGALT00010045092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026939.1", "url": "https://www.ensembl.org/id/ENSGALP00010026939.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 337, "end_pos": 513, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" }, { "id": "PS50866", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GOLD", "eco_id": "ECO_0000259", "start_pos": 540, "end_pos": 691, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZEG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG4" }, { "id": "PS50904", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRELI/MSF1", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 197, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEV2-1", "uniprot_ac": "A0A8V0ZEV2", "uniprot_id": "A0A8V0ZEV2_CHICK", "mass": { "chemical_mass": 120652.0, "monoisotopic_mass": 120652.0 }, "refseq": { "ac": "XP_004945126", "name": "myocardin-related transcription factor B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945126" }, "gene_names": [ { "name": "MKL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ] }, { "name": "MKL2", "type": "synonym", "evidence": [ { "id": "XP_004945126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945126" } ] } ], "protein_names": [ { "name": "Myocardin related transcription factor B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2/entry#names_and_taxonomy" } ] }, { "name": "myocardin-related transcription factor B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945126" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945126.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945126" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MKL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZEV2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416421", "url": "https://www.ncbi.nlm.nih.gov/gene/416421", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416421", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416421", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTFTQHV", "url": "https://omabrowser.org/oma/group/DTFTQHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEV2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHVGTVDAEDDPGTLPRLAPSPHSEAVAHEFKELSLQPSQYLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIAVGQESYPQALDDYSFDEDSSDALSPDQPASQESQGSASPGEPKTSDSPSPITPNATTSTQYPPLTSPVPEFLKTPPTIEHVTRSTATATMTTSTVSAAKPGPTLVKQSHPKNPNDKHRSKKCKEPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLSDKQNNNGNTPLNALNNNTPTSAANSTRQNSSVPSRKPGPLPSSLDDLKVAELKMELKLRGLPVSGTKTDLIERLKPYQDLNNNGVTTCSSVTITTSTGATGNTGEMAVAFPVTTLNKTVANTISSFPPEKTTTGPGCKAVNTENVSSPLPISPSPSEQSNLSTDDTGMADTFTEMMTMVSPSQFLSTSPLRTNTSDDNQNCSSGNISSMEFDVAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRVQQQQSQTSGNSAALEQKQFSAAVKDENVLTDCSSTSQSVSVDSHPLGQSVYTSGQNPVAKKAVIIKQEIPVAKADPQNAISQFYVNPQRQPQTAVVAPPQALLTTQGTAQLLLPLSIQGPNSTTSVQLPVGNIKLQGQSQAGIQTPSQIPAPILSSGLVQTAPKTHTPQSKQNTITQHALGQTQQIRKVFPPTTSTTVFSYQTAPVTTPSQSFINKTSNSNIHSGNNQTPSVQNGPAPPNKPGSPSQGQSYIVQQSLFNNTVSKTKDPPRYEEAIKQTRNIQTSHREISSTHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTANITTMPVNTVISRPPPQIQMAPPPVSLEPTTSLSISLENQLEALLDGTLPSGNEIPQLASGNEDRESFSLIEDLQNDLLNHSSILDHSHSPMETSDPQFTTNSSCLSLDLPDTNLDNMEWLDITMPSSSSGLTPLSSTAPSVFSTDFLDTQDLQLHWD", "length": 1104, "header": "tr|A0A8V0ZEV2-1|A0A8V0ZEV2_CHICK Isoform 1 of Myocardin related transcription factor B OS=Gallus gallus OX=9031 GN=MKL2 PE=4 SV=1 CANONICAL=A0A8V0ZEV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2/entry#A0A8V0Z7P1-1", "sequence": { "sequence": "MDHVGTVDAEDDPGTLPRLAPSPHSEAVAHEFKELSLQPSQYLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIAVGQESYPQALDDYSFDEDSSDALSPDQPASQESQGSASPGEPKTSDSPSPITPNATTSTQYPPLTSPVPEFLKTPPTIEHVTRSTATATMTTSTVSAAKPGPTLVKQSHPKNPNDKHRSKKCKEPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLSDKQNNNGNTPLNALNNNTPTSAANSTRQNSSVPSRKPGPLPSSLDDLKVAELKMELKLRGLPVSGTKTDLIERLKPYQDLNNNGVTTCSSVTITTSTGATGNTGEMAVAFPVTTLNKTVANTISSFPPEKTTTGPGCKAVNTENVSSPLPISPSPSEQSNLSTDDTGMADTFTEMMTMVSPSQFLSTSPLRTNTSDDNQNCSSGNISSMEFDVAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRVQQQQSQTSGNSAALEQKQFSAAVKDENVLTDCSSTSQSVSVDSHPLGQSVYTSGQNPVAKKAVIIKQEIPVAKADPQNAISQFYVNPQRQPQTAVVAPPQALLTTQGTAQLLLPLSIQGPNSTTSVQLPVGNIKLQGQSQAGIQTPSQIPAPILSSGLVQTAPKTHTPQSKQNTITQHALGQTQQIRKVFPPTTSTTVFSYQTAPVTTPSQSFINKTSNSNIHSGNNQTPSVQNGPAPPNKISSTHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTANITTMPVNTVISRPPPQIQMAPPPVSLEPTTSLSISLENQLEALLDGTLPSGNEIPQLASGNEDRESFSLIEDLQNDLLNHSSILDHSHSPMETSDPQFTTNSSCLSLDLPDTNLDNMEWLDITMPSSSSGLTPLSSTAPSVFSTDFLDTQDLQLHWD", "length": 1058, "header": "tr|A0A8V0Z7P1-1|A0A8V0ZEV2_CHICK Computationally mapped isoform of Myocardin related transcription factor B OS=Gallus gallus OX=9031 GN=MKL2 PE=4 SV=1 CANONICAL=A0A8V0ZEV2-1" }, "locus": { "chromosome": "14", "start_pos": 761539, "end_pos": 718539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049523.1", "url": "https://www.ensembl.org/id/ENSGALT00010049523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029264.1", "url": "https://www.ensembl.org/id/ENSGALP00010029264.1" } ] } }, { "isoform_ac": "A0A8V0ZDG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2/entry#A0A8V0ZDG6-1", "sequence": { "sequence": "MIDSCKKQQQGFSEILPAGDVKPLKEKECLEVNSQRSLKEVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIAVGQESYPQALDDYSFDEDSSDALSPDQPASQESQGSASPGEPKTSDSPSPITPNATTSTQYPPLTSPVPEFLKTPPTIEHVTRSTATATMTTSTVSAAKPGPTLVKQSHPKNPNDKHRSKKCKEPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLSDKQNNNGNTPLNALNNNTPTSAANSTRQNSSVPSRKPGPLPSSLDDLKVAELKMELKLRGLPVSGTKTDLIERLKPYQDLNNNGVTTCSSVTITTSTGATGNTGEMAVAFPVTTLNKTVANTISSFPPEKTTTGPGCKAVNTENVSSPLPISPSPSEQSNLSTDDTGMADTFTEMMTMVSPSQFLSTSPLRTNTSDDNQNCSSGNISSMEFDVAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRVQQQQSQTSGNSAALEQKQFSAAVKDENVLTDCSSTSQSVSVDSHPLGQSVYTSGQNPVAKKAVIIKQEIPVAKADPQNAISQFYVNPQRQPQTAVVAPPQALLTTQGTAQLLLPLSIQGPNSTTSVQLPVGNIKLQVFPPTTSTTVFSYQTAPVTTPSQSFINKTSNSNIHSGNNQTPSVQNGPAPPNKPGSPSQGQSYIVQQSLFNNTVSKTKDPPRYEEAIKQTRNIQTSHREISSTHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTANITTMPVNTVISRPPPQIQMAPPPVSLEPTTSLSISLENQLEALLDGTLPSGNEIPQLASGNEDRESFSLIEDLQNDLLNHSSILDHSHSPMETSDPQFTTNSSCLSLDLPDTNLDNMEWLDITMPSSSSGLTPLSSTAPSVFSTDFLDTQDLQLHWD", "length": 1041, "header": "tr|A0A8V0ZDG6-1|A0A8V0ZDG6_CHICK Computationally mapped isoform of Myocardin related transcription factor B OS=Gallus gallus OX=9031 GN=MKL2 PE=4 SV=1 CANONICAL=A0A8V0ZEV2-1" }, "locus": { "chromosome": "14", "start_pos": 761539, "end_pos": 729483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049517.1", "url": "https://www.ensembl.org/id/ENSGALT00010049517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029261.1", "url": "https://www.ensembl.org/id/ENSGALP00010029261.1" } ] } }, { "isoform_ac": "A0A8V0ZEU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2/entry#A0A8V0ZEU7-1", "sequence": { "sequence": "MIDSCKKQQQGFSEILPAGDVKPLKEKECLEVNSQRSLKEVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIAVGQESYPQALDDYSFDEDSSDALSPDQPASQESQGSASPGEPKTSDSPSPITPNATTSTQYPPLTSPVPEFLKTPPTIEHVTRSTATATMTTSTVSAAKPGPTLVKQSHPKNPNDKHRSKKCKEPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLSDKQNNNGNTPLNALNNNTPTSAANSTRQNSSVPSRKPGPLPSSLDDLKVAELKMELKLRGLPVSGTKTDLIERLKPYQDLNNNGVTTCSSVTITTSTGATGNTGEMAVAFPVTTLNKTVANTISSFPPEKTTTGPGCKAVNTENVSSPLPISPSPSEQSNLSTDDTGMADTFTEMMTMVSPSQFLSTSPLRTNTSDDNQNCSSGNISSMEFDVAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRVQQQQSQTSGNSAALEQKQFSAAVKDENVLTDCSSTSQSVSVDSHPLGQSVYTSGQNPVAKKAVIIKQEIPVAKADPQNAISQFYVNPQRQPQTAVVAPPQALLTTQGTAQLLLPLSIQGPNSTTSVQLPVGNIKLQGQSQAGIQTPSQIPAPILSSGLVQTAPKTHTPQSKQNTITQHALGQTQQIRKVFPPTTSTTVFSYQTAPVTTPSQSFINKTSNSNIHSGNNQTPSVQNGPAPPNKPGSPSQGQSYIVQQSLFNNTVSKTKDPPRYEEAIKQTRNIQTSHREISSTHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTANITTMPVNTVISRPPPQIQMAPPPVSLEPTTSLSISLENQLEALLDGTLPSGNEIPQLASGNEDRESFSLIEDLQNDLLNHSSILDHSHSPMETSDPQFTTNSSCLSLDLPDTNLDNMEWLDITMPSSSSGLTPLSSTAPSVFSTDFLDTQDLQLHWD", "length": 1093, "header": "tr|A0A8V0ZEU7-1|A0A8V0ZEU7_CHICK Computationally mapped isoform of Myocardin related transcription factor B OS=Gallus gallus OX=9031 GN=MKL2 PE=4 SV=1 CANONICAL=A0A8V0ZEV2-1" }, "locus": { "chromosome": "14", "start_pos": 761539, "end_pos": 729483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049511.1", "url": "https://www.ensembl.org/id/ENSGALT00010049511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029257.1", "url": "https://www.ensembl.org/id/ENSGALP00010029257.1" } ] } }, { "isoform_ac": "A0A8V0ZEV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2/entry#A0A8V0ZEV2-1", "sequence": { "sequence": "MDHVGTVDAEDDPGTLPRLAPSPHSEAVAHEFKELSLQPSQYLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIAVGQESYPQALDDYSFDEDSSDALSPDQPASQESQGSASPGEPKTSDSPSPITPNATTSTQYPPLTSPVPEFLKTPPTIEHVTRSTATATMTTSTVSAAKPGPTLVKQSHPKNPNDKHRSKKCKEPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLSDKQNNNGNTPLNALNNNTPTSAANSTRQNSSVPSRKPGPLPSSLDDLKVAELKMELKLRGLPVSGTKTDLIERLKPYQDLNNNGVTTCSSVTITTSTGATGNTGEMAVAFPVTTLNKTVANTISSFPPEKTTTGPGCKAVNTENVSSPLPISPSPSEQSNLSTDDTGMADTFTEMMTMVSPSQFLSTSPLRTNTSDDNQNCSSGNISSMEFDVAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRVQQQQSQTSGNSAALEQKQFSAAVKDENVLTDCSSTSQSVSVDSHPLGQSVYTSGQNPVAKKAVIIKQEIPVAKADPQNAISQFYVNPQRQPQTAVVAPPQALLTTQGTAQLLLPLSIQGPNSTTSVQLPVGNIKLQGQSQAGIQTPSQIPAPILSSGLVQTAPKTHTPQSKQNTITQHALGQTQQIRKVFPPTTSTTVFSYQTAPVTTPSQSFINKTSNSNIHSGNNQTPSVQNGPAPPNKPGSPSQGQSYIVQQSLFNNTVSKTKDPPRYEEAIKQTRNIQTSHREISSTHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTANITTMPVNTVISRPPPQIQMAPPPVSLEPTTSLSISLENQLEALLDGTLPSGNEIPQLASGNEDRESFSLIEDLQNDLLNHSSILDHSHSPMETSDPQFTTNSSCLSLDLPDTNLDNMEWLDITMPSSSSGLTPLSSTAPSVFSTDFLDTQDLQLHWD", "length": 1104, "header": "tr|A0A8V0ZEV2-1|A0A8V0ZEV2_CHICK Isoform 1 of Myocardin related transcription factor B OS=Gallus gallus OX=9031 GN=MKL2 PE=4 SV=1 CANONICAL=A0A8V0ZEV2-1" }, "locus": { "chromosome": "14", "start_pos": 761539, "end_pos": 718539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049519.1", "url": "https://www.ensembl.org/id/ENSGALT00010049519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029262.1", "url": "https://www.ensembl.org/id/ENSGALP00010029262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416421", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AN60-1", "protein_name": "Myocardin related transcription factor B", "gene_name": "MRTFB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDHTGALDAEDELGPLAHLAPSPQSEAVAHELQELSLQSSQHLPPLNERKNVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVGKEDYPQTQGDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSESPSPVTANTPAQFTSVSPAVPEFLKSPTTDQPPTRSAAPVLPANTVSSAKPGPALVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQQQHYNYQTILPAPLKPLNDKNNNSGNPALNNTTPNTPRQNASAPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQELSGSGAAAGGIVAVSTSAIVTSNPEVTVALPVTTLQNSVTSSGATFKADGPPTGTSSAAHLETGSSPLPVSPSASEQSSLSAEDTSMADTFTEIMTMMSPSQFLCSSPLRAASTEDSLSPTSSSLSNLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQQQQQRPLEPLPNAPALPAAKAEQTRSAPAAATAPSVKDEAPLPDGPGPAPAPAGGQSLVAKKAVVIKQEVPAAPAEPHSLVPQFYVSSQGPPPAGAAGPQALLTTQTAQLLLPVSIQGSSVTSVQLPVGSLRLQTPPQTGIQTQPQIAAATLPAGLAQTVPQKQDAFTPHMLSQPQQVRKVFTNSASNSVLPYQTPPAPAAQQSFLSKTSNGVLPSRSTALPPPLQNGPNPPSKPASPPPPQQFVVPHSLFGSPVPKAKDPPRYEEAIKQTRSAQSSLPEVASAHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTASITTMPVSTVVSRPPPQVQMAPPISLEPMGSLSASLENQLEAFLDGTLPSANEIAPLQSSSEDREPFSLIEDLQNDLLSHAAVLDPSHSPMETAEAQFAASAPCLSLDLSDSNLDNMEWLDITMPGTSAALTPLSAAAPSMFSADFLDPQDLPLPWD", "length": 1087 }, "evidence": [ { "id": "A0A8V0ZEV2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GJE3-1", "protein_name": "Myocardin related transcription factor B", "gene_name": "Mrtfb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGARTEGQNGAVDPRACLNTFVLTGENLSGWNNTMDHRGALDTEEELGPLAHLAPSPQSEAVAHEFQELSLQSSQHLPTLNERKNVLQLKLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVVKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTASTPVQFTSVSPAVPEFLKSPVDQPPTRSTASVLPTNTVSSAKSGPTLVKQSHPKNPNDKHRNKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPHMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPVKTDKNSSSSSSSSSSSSTGVPARRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVTSNNLATGSIVAVSSAAIVTSNPEVTVTLPVTTLHNAVTNSVSTFKADLPPSGSSSVPHVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQFLCSSPLRVASHEDSLSPTSSTLSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEEEKRGQQRPPGPQPNGSTHPFTSDLKLGNVRSSVKDETSLPDCSSPQQSIPVPGHSVGQPISTGSQTLVAKKAVVVKQEVPMAQTEQQNVVSQFYLSSQGQPPAFVAQPQALLTTQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAQGGVQAQPQVAAATQVPAAALPSALASALPQKQEAFPQHVLVQPQPVRKVFTNSAPNTVLQYQRQPGPATPQPFVSKTSNPAVQSRSTPLVPLQNGPGPASKPSSPPPPQQFVVQHSLFATPVTKTKDPPRYEEAIKQTRSTQSALPEVSSVHSQQMDDLFDILIKSGEISFPIKEKPSPISKMKPVTASITTMPVNTVVSRPPPQVQIAPPVSLEPVNSLSASLENQLEAFLDGALPSANDIAPLQGSSEDREPLSLIEDLQNDLLSHSSMLYQSHSPMETSEAQFVSGTPCLSLDLSDPNLDNMEWLDITMPTTSSGLTPLSTTSPSMFSTDFLDPQDLPLPWD", "length": 1124 }, "evidence": [ { "id": "A0A8V0ZEV2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59759-1", "protein_name": "Myocardin-related transcription factor B", "gene_name": "Mrtfb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDSSKKQPQGFPEILTAEDFEPFKEKECLEGSNQKSLKEVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVVKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTASTPAQFTSVSPAVPEFLKTPLTADQPPTRSTAPVLPTNTVSSAKSGPMLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIKTDKNSSSGSNSGSSSSMPARRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVTSSNLATGSIVAVSSATIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLALPATSSVPHVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSHDDSLSPSSSTLSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQRPPDPQPSDPPHPFNTSDPKHGSVGSSIKDEASLPDCSSPQQPITVPGHSVGQPISTGSQTLVAKKTVVVKQEVPMAQAEQQNVVSQFYLSSQGQPPALVAQPQALLTTQTTQLLLPVSIQGSNVTSVQLPVGSLQLQTPAQGRVQAQPHVAAATQVPAAALPSALTSALPQKQEAFPQHVLGQPQPVRKVFTNSAPNTVLQYQRQPGPTNQQPFVSKTSNPALQSRTAPLAPLQNGPSLASKPSSPPPPQQFVVQHSLFATPITKTKDPPRYEEAIKQTRSTQPALPEVSSVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMKPVTASITTMPVNTVVSRPPPQVQIAPPVSLEPVNSLSASLENQLEAFLDGTLPSATDTGPLQNSSEDRESFSLIEDLQNDLLSHSSMLYQSHSPMETSEAQLVSGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSTTAPSMFSADFLDPQDLPLPWD", "length": 1080 }, "evidence": [ { "id": "A0A8V0ZEV2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULH7-1", "protein_name": "Myocardin-related transcription factor B", "gene_name": "MRTFB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIDSSKKQQQGFPEILTAGDFEPLKEKECLEGSNQKSLKEVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVGKEDYPHTQGDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEFLKTPPTADQPPPRPAAPVLPTNTVSSAKPGPALVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQKQHYNYQTILPAPFKPLNDKNSNSGNSALNNATPNTPRQNTSTPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVNSSGLAAGGIVAVSSSAIVTSNPEVTVALPVTTLHNTVTSSVSTLKAELPPTGTSNATRVENVHSPLPISPSPSEQSSLSTDDTNMADTFTEIMTMMSPSQFLSSSPLRMTNNEDSLSPTSSTLSNLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQQRPLEAQPSAPGHSVKSDQKHGSLGSSIKDEASLPDCSSSRQPIPVASHAVGQPVSTGGQTLVAKKAVVIKQEVPVGQAEQQSVVSQFYVSSQGQPPPAVVAQPQALLTTQTAQLLLPVSIQGSSVTSVQLPVGSLKLQTSPQAGMQTQPQIATAAQIPTAALASGLAPTVPQTQDTFPQHVLSQPQQVRKVFTNSASSNTVLPYQRHPAPAVQQPFINKASNSVLQSRNAPLPSLQNGPNTPNKPSSPPPPQQFVVQHSLFGSPVAKTKDPPRYEEAIKQTRSTQAPLPEISNAHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTASITTMPVNTVVSRPPPQVQMAPPVSLEPMGSLSASLENQLEAFLDGTLPSANEIPPLQSSSEDREPFSLIEDLQNDLLSHSGMLDHSHSPMETSETQFAAGTPCLSLDLSDSNLDNMEWLDITMPNSSSGLTPLSTTAPSMFSADFLDPQDLPLPWD", "length": 1088 }, "evidence": [ { "id": "A0A8V0ZEV2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" }, { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" }, { "name": "positive regulation of striated muscle tissue development", "id": "GO:0045844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045844", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" }, { "start_pos": 947, "end_pos": 949, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV2" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 442, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1026, "end_pos": 1028 }, { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 845, "end_pos": 847 }, { "start_pos": 877, "end_pos": 879 }, { "start_pos": 947, "end_pos": 949 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEV4-1", "uniprot_ac": "A0A8V0ZEV4", "uniprot_id": "A0A8V0ZEV4_CHICK", "mass": { "chemical_mass": 82386.0, "monoisotopic_mass": 82386.0 }, "refseq": { "ac": "XP_015145442", "name": "oxysterol-binding protein-related protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145442" }, "gene_names": [ { "name": "OSBPL11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ] }, { "name": "OSBPL11", "type": "synonym", "evidence": [ { "id": "XP_015145442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145442" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4/entry#names_and_taxonomy" } ] }, { "name": "oxysterol-binding protein-related protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145442" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145442" } ] }, { "annotation": "Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25-hydroxycholesterol. Interacts with OSBPL9 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z7P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P6#function" }, { "database": "UniProtKB", "id": "ARBA00058048", "url": "https://www.uniprot.org/uniprotkb/ARBA00058048#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSBPL11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4", "locus": { "chromosome": "7", "start_pos": 27767147, "end_pos": 27814728, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020497", "url": "https://www.ensembl.org/id/ENSGALG00010020497" } ] } } ], "crossref": [ { "id": "A0A8V0ZEV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424262", "url": "https://www.ncbi.nlm.nih.gov/gene/424262", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424262", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424262", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDHKEDD", "url": "https://omabrowser.org/oma/group/CDHKEDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7P6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEV4", "url": "https://www.orthodb.org/?gene=A0A8V0ZEV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015145442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145442", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "81667", "url": "https://www.rhea-db.org/rhea/81667", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z7P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQCADPAAAVKGPEGEGKAEPAAAGKSGGRGAKGWQYSDHMENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 734, "header": "tr|A0A8V0ZEV4-1|A0A8V0ZEV4_CHICK Isoform 1 of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A8V0ZEV4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4/entry#A0A8V0Z7P6-1", "sequence": { "sequence": "MQKISFGDEEELPSLLPPRLLSCSVLLTPQALSDHMENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 729, "header": "tr|A0A8V0Z7P6-1|A0A8V0ZEV4_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A8V0ZEV4-1" }, "locus": { "chromosome": "7", "start_pos": 27807268, "end_pos": 27769002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049536.1", "url": "https://www.ensembl.org/id/ENSGALT00010049536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029269.1", "url": "https://www.ensembl.org/id/ENSGALP00010029269.1" } ] } }, { "isoform_ac": "A0A8V0ZDH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4/entry#A0A8V0ZDH1-1", "sequence": { "sequence": "MENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEQGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 695, "header": "tr|A0A8V0ZDH1-1|A0A8V0ZDH1_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A8V0ZEV4-1" }, "locus": { "chromosome": "7", "start_pos": 27786546, "end_pos": 27769002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049529.1", "url": "https://www.ensembl.org/id/ENSGALT00010049529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029266.1", "url": "https://www.ensembl.org/id/ENSGALP00010029266.1" } ] } }, { "isoform_ac": "A0A8V0ZDH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4/entry#A0A8V0ZDH6-1", "sequence": { "sequence": "MLIQTPCPWAGERRRESDHMENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 713, "header": "tr|A0A8V0ZDH6-1|A0A8V0ZDH6_CHICK Computationally mapped isoform of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A8V0ZEV4-1" }, "locus": { "chromosome": "7", "start_pos": 27799530, "end_pos": 27769002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049540.1", "url": "https://www.ensembl.org/id/ENSGALT00010049540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029271.1", "url": "https://www.ensembl.org/id/ENSGALP00010029271.1" } ] } }, { "isoform_ac": "A0A8V0ZEV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4/entry#A0A8V0ZEV4-1", "sequence": { "sequence": "MQCADPAAAVKGPEGEGKAEPAAAGKSGGRGAKGWQYSDHMENICGYLMKYTNLVTGWQYRFFVLNNDAGLLEYFVNEQSRHLKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASQGSINSPGLQRRPSQNAVSFFNVGHHRLPAGKRGPILQPDHLVDVREMMSQAEGQQRDLIRSIECLPVSGHLTSLDQDLLMLKATSMATMNCLNDCFHILQLQHASQQKGSLPAGTTISWLEPKISLSNHFKNGAAQNFPAEINKPASVREEQSNAEPCQLTREPEEINPDEELEDLCDDKEDDLGGVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATPEERMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVATDGGSNISAHSEQIALSKDLEGQAESDYYTVKFVAEQVSHHPPVSGFYAECVERKMCVNAHVWTKSKFLGMSIGVTMVGEGLLSLLEHEEEYTFSLPCAYARSILTVPWVELGGKVNINCAKTGYSASINFHTKPFYGGKLHRVTGEVKQNATNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLSVTRKRVRPIEKQGPFESRRLWQHVTESLRDGDIDKATEHKRALEERQRNEERLRAETETPWCTKYFIKEGDGWVYHKPLWRAVSAVQTQQMDAN", "length": 734, "header": "tr|A0A8V0ZEV4-1|A0A8V0ZEV4_CHICK Isoform 1 of Oxysterol-binding protein OS=Gallus gallus OX=9031 GN=OSBPL11 PE=3 SV=1 CANONICAL=A0A8V0ZEV4-1" }, "locus": { "chromosome": "7", "start_pos": 27798529, "end_pos": 27769002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049534.1", "url": "https://www.ensembl.org/id/ENSGALT00010049534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029267.1", "url": "https://www.ensembl.org/id/ENSGALP00010029267.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424262", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424262", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TP25-1", "protein_name": "Oxysterol-binding protein", "gene_name": "OSBPL11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFEVKMQGGEPLSTMKVSESEGRLEGLATAVTPNKNSSNSSCGGGISSSSSGSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNAISFFNVGHSKLQSVSKRANLPPDHLVEVREMMSHAEGQQRDLIRRIECLPASGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKIPLSNHYKNEADQPFAAEQSKPVAVPEEQCVAESGLLTREPEEINADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASSVISSSTQAGTNHAPPSEETLSQVGSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLSLLEHGEEYTFSLPCAYARSILTVPWVELGGKISVNCAKTGYSASITFHTKPFYGGKLHRVTGEVKHNITNTVVCKVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 757 }, "evidence": [ { "id": "A0A8V0ZEV4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CI95-1", "protein_name": "Oxysterol-binding protein-related protein 11", "gene_name": "Osbpl11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGGEPASVMKVSESEGKLEGLATAVTPNKNSGNSSCGGAISSSSSNSSRGGSAKGWQYSDHMESVNGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSGNSPISQRRPSQNAMSFFNVGHSKLQSVNKRAHLHPDHLVEVREMMSHAEGQQRDLIRRIECLPASGLLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGALPSGTTIEWLEPKIPLSNHYKNGAEQPFATEPNKPMGAPEAQCVAESGVLAREPEDISADDEVEDTCDNKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIGITNGATPEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWRMPKSEVASGVSSSSSTPAITDHAPLPEEAPTQSVSDCYTVRFVAEQVSHHPPVSGFYAECAERKMCVNAHVWTKSKFLGMSIGVTMVGEGVLCLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKYNLTNTVVCRVQGEWNSVLEFTYSNGETKFVDLAKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKRSLEERQRTEERLRTETGTPWKTKYFIKEGDGWVYHKPLWKGIPSQPAE", "length": 751 }, "evidence": [ { "id": "A0A8V0ZEV4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXB4-1", "protein_name": "Oxysterol-binding protein-related protein 11", "gene_name": "OSBPL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE", "length": 747 }, "evidence": [ { "id": "A0A8V0ZEV4", "url": "https://omabrowser.org/oma/group/A0A8V0ZEV4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "endoplasmic reticulum-trans-Golgi network membrane contact site", "id": "GO:0160258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160258", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "phospholipid transfer to membrane", "id": "GO:0006649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "lysosomal membrane organization", "id": "GO:0097212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" }, { "name": "phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "id": "GO:0160270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81667", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "81667", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81667" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV4" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 138, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 460, "end_pos": 462 }, { "start_pos": 605, "end_pos": 607 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEN7-1", "uniprot_ac": "A0A8V0ZEN7", "uniprot_id": "A0A8V0ZEN7_CHICK", "mass": { "chemical_mass": 53580.0, "monoisotopic_mass": 53580.0 }, "refseq": { "ac": "XP_040503795", "name": "meiosis-specific with OB domain-containing protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503795" }, "gene_names": [ { "name": "MEIOB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ] }, { "name": "MEIOB", "type": "synonym", "evidence": [ { "id": "XP_040503795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503795" } ] } ], "protein_names": [ { "name": "Meiosis-specific with OB domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#names_and_taxonomy" } ] }, { "name": "meiosis-specific with OB domain-containing protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040503795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503795" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503795" } ] }, { "annotation": "Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7#function" }, { "database": "UniProtKB", "id": "ARBA00055425", "url": "https://www.uniprot.org/uniprotkb/ARBA00055425#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEIOB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7", "locus": { "chromosome": "14", "start_pos": 6058233, "end_pos": 6071605, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018717", "url": "https://www.ensembl.org/id/ENSGALG00010018717" } ] } } ], "crossref": [ { "id": "A0A8V0ZEN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "416539", "url": "https://www.ncbi.nlm.nih.gov/gene/416539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IYLKFVV", "url": "https://omabrowser.org/oma/group/IYLKFVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7S7", "url": "https://www.orthodb.org/?gene=A0A8V0Z7S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8R4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEM8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEN2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZEN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21166:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21166:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYSSSTRDFVALSDLHPNLARPNVIGVVIGKTDVRGFPDRKNIGSERYTFSFTIRDSPTYFINVNSWGREEYIRSLSESFRVGDCVTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPETAEANVLFSFIRESAQTGALHDKMEEQSKESINLETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 475, "header": "tr|A0A8V0ZEN7-1|A0A8V0ZEN7_CHICK Isoform 1 of Meiosis-specific with OB domain-containing protein OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#A0A8V0Z7S7-1", "sequence": { "sequence": "MAYSSSTRDFVALSDLHPNLARPNVIGVVIGKTDVRGFPDRKNIGSERYTFSFTIRDSPTYFINVNSWGREEYIRSLSESFRVGDCVTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPVETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 441, "header": "tr|A0A8V0Z7S7-1|A0A8V0ZEN7_CHICK Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "locus": { "chromosome": "14", "start_pos": 6069985, "end_pos": 6058601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045245.1", "url": "https://www.ensembl.org/id/ENSGALT00010045245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027012.1", "url": "https://www.ensembl.org/id/ENSGALP00010027012.1" } ] } }, { "isoform_ac": "A0A8V0Z8R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#A0A8V0Z8R4-1", "sequence": { "sequence": "MFVVRSIRLQCSVNRCKIQCMLLIKLLNCPMLIDCYGSSAGTRKLWTMADIGSERYTFSFTIRDSPTYFINVNSWGREEYIRSLSESFRVGDCVTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPETAEANVLFSFIRESAQTGALHDKMEEQSKESINLETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 482, "header": "tr|A0A8V0Z8R4-1|A0A8V0ZEN7_CHICK Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "locus": { "chromosome": "14", "start_pos": 6067694, "end_pos": 6058601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045237.1", "url": "https://www.ensembl.org/id/ENSGALT00010045237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027006.1", "url": "https://www.ensembl.org/id/ENSGALP00010027006.1" } ] } }, { "isoform_ac": "A0A8V0ZEM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#A0A8V0ZEM8-1", "sequence": { "sequence": "MVPLLGQGSCGLWQNVIGVVIGKTDVRGFPDRKNIGSERYTFSFTIRDSPTYFINVNSWGREEYIRSLSESFRVGDCVTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPVETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 432, "header": "tr|A0A8V0ZEM8-1|A0A8V0ZEM8_CHICK Computationally mapped isoform of Meiosis specific with OB-fold OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "locus": { "chromosome": "14", "start_pos": 6067588, "end_pos": 6058601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045234.1", "url": "https://www.ensembl.org/id/ENSGALT00010045234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027004.1", "url": "https://www.ensembl.org/id/ENSGALP00010027004.1" } ] } }, { "isoform_ac": "A0A8V0ZEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#A0A8V0ZEN2-1", "sequence": { "sequence": "MKAVTMKTMHTATSSHFVPIKCLEDSCGTLAIMRAVWPDNVFRMKAFSRSCCTFTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPETAEANVLFSFIRESAQTGALHDKMEEQSKESINLETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 442, "header": "tr|A0A8V0ZEN2-1|A0A8V0ZEN2_CHICK Computationally mapped isoform of Meiosis specific with OB-fold OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "locus": { "chromosome": "14", "start_pos": 6064325, "end_pos": 6058601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045242.1", "url": "https://www.ensembl.org/id/ENSGALT00010045242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027009.1", "url": "https://www.ensembl.org/id/ENSGALP00010027009.1" } ] } }, { "isoform_ac": "A0A8V0ZEN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7/entry#A0A8V0ZEN7-1", "sequence": { "sequence": "MAYSSSTRDFVALSDLHPNLARPNVIGVVIGKTDVRGFPDRKNIGSERYTFSFTIRDSPTYFINVNSWGREEYIRSLSESFRVGDCVTIENPLVQSKDGEKEEKFNPITPSCYKLLISENHSVVKTSSCYEMDTKLLSLLHLPVKDPQDYYSLGDITANGQSLDGRILNVLAAVMSVGEPKYFITSDKRKGQRCEVKLYDETEMSFPIICWDNESIQLAQSWIPRETVIFASDVRVNFDKFRNCMTATVISKTIITTNPETAEANVLFSFIRESAQTGALHDKMEEQSKESINLETIVDVYTVKQLKEKALQSDGKPEPVFGIIYGYISMLDIDDNVSKVIRNRCSVCRFVVNEMSNTCTFCGDISSDSKSTFVSFDILVDLTDHTGTLYSCYLSDCVAEETLGCTVQEFLTLAEDKRTALKWQLLLERSKIYFKITLSPNWRSGLKANILSCKLANPIEASQSLLGKKLQHVAW", "length": 475, "header": "tr|A0A8V0ZEN7-1|A0A8V0ZEN7_CHICK Isoform 1 of Meiosis-specific with OB domain-containing protein OS=Gallus gallus OX=9031 GN=MEIOB PE=3 SV=1 CANONICAL=A0A8V0ZEN7-1" }, "locus": { "chromosome": "14", "start_pos": 6069985, "end_pos": 6058601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045248.1", "url": "https://www.ensembl.org/id/ENSGALT00010045248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027014.1", "url": "https://www.ensembl.org/id/ENSGALP00010027014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AB97-1", "protein_name": "Meiosis-specific with OB domain-containing protein", "gene_name": "MEIOB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPGRRLLLASAGAEAGAGRSVGGQTRRDTDRIMANSIVSKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSAAHFVNVASWGNEDYVRALSDSFRVGACVIIENPLIQIKDLEREEKFSPATPSHCKLLLSENHSRMKVCSNYEVDTKLLSLIYLPVKESSDYYSLGDIVANGHSLDGRIINVLAAVRSVGKPKYFTTSDQRKGQRCEVKLYDETESSFAMICWDNESILLAQSWMPRETVIFASDVRISFDKFRNCMTATVISKTIITTNPDTPEANILLHFIRENKETNPLDDEIGSCLKESINLSTIDDVYTVEQLKVKALKNEGKADPFYGILYAYISALNIDDETTKVVRSKCSGCGSIVNEASSICTTCNRDSSEFKSAFLSFDMLIDLSDHTGTLHFCSLTGSVAEETLGCTVNEFLAMTDEQRTALKWQLLLERTKIYLKVSLLHRARARLRMSVLSCKLADPVEASRSLSG", "length": 500 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8RX28-1", "protein_name": "Meiosis-specific with OB domain-containing protein isoform X1", "gene_name": "meiob", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTYAPMGSYVPISDLNINITHSKVVGVIIGKTDSRGFPDRKNVGSERFTFSFTIKDSPEHFINVSAWGNEEYIQALSCRFQIGDCVVIENPLVVTKDYEKEERFCPSTPSSYRLLLTETHSSIRICSDIDTEARILPLFHIPIKDPRDFYSLGDITANGQSLDGHVINILAAVQSVGEEKFFTKSGGCKGQRIEIKLFDDTGRSFPFVCWDKENIRLVQTLTQRETVLFIADARITFDSFRKSMVATAISKTIITVNPDTAEANQLYTFVRELLQSGGLDDQDFLSGDDVLLDSIRDVMTVSQLKTRSQENADAIHCIIYGFITCFDLGSSPSKIITKRCARCKFRINEESWTCSSDICPNQGQELQANECFDVLVDISDHTGTLQSCNLVGTVAEKTLGCKTEEFLCLSEYQRTSLQWKFLLERCKIYLKVLPSPRRRSGMKADILSCGLADPVEVKQNLASFVV", "length": 466 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2N2R1-1", "protein_name": "Meiosis-specific with OB domain-containing protein", "gene_name": "Meiob", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANSFALKNFTPLSDLHPNMASLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTLRDSPNHFVNVSSWGSEDYIRPLSENFKVGECVIIENPLIQRKETEREEKFSPATPSNWKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKHFTTSDGRKGQRCEVKLFDETEPSFTVTCWDNESILLAQSWIPRETVIFASDVRINFNKFQNCMAATVISKTIITANPDTPEANILLNYIRENKETNVADEIESYLKESINLNTIVDVYTVEQLKVKALRNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCYNCGYIVNEASNTCTICNKDSSRLKPFFLSFDVLVDLTDHTGTLHSCSLTGSIAEETLGCTINEFLAMTSEQKTKLKWQFLLERSKIYLKLILSHRARGGLKVSILSCKLADPTEASRNLAGQGHT", "length": 470 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0BMX9-1", "protein_name": "Meiosis-specific with OB domain-containing protein", "gene_name": "Meiob", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPNHFVNVSSWGSEDYIRSLSDNFKVGECVIIENPLIQRKETEREERFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNFIRENKETSIADEIDSYLKESVNLNTIVNVYTVEQLKGKALENEGKVDPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNDASNTCTICSKDSSRSRSFCLSFDVLVDLTDHTGTLRSCSLSGSVAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPIEASRDLAGQGHT", "length": 470 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N635-1", "protein_name": "Meiosis-specific with OB domain-containing protein", "gene_name": "MEIOB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANSFAARIFTTLSDLQTNMANLKVIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPAHFVNAASWGNEDYIKSLSDSFRVGDCVIIENPLIQRKEIEREEKFSPATPSNCKLLLSENHSTVKVCSSYEVDTKLLSLIHLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEPKYFTTSDRRKGQRCEVRLYDETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDKFRNCMTATVISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDVYTVEQLKGKALKNEGKADPSYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCTTCNKNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTFVLSHRARSGLKISVLSCKLADPTEASRNLSGQKHV", "length": 442 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D513-1", "protein_name": "Meiosis-specific with OB domain-containing protein", "gene_name": "Meiob", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPCHFVNVSSWGSEDYIRSLSESFRVAECVIIENPLIQRKDTEREEKFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNYIRENKETNVADEIDSYLKESVNLNTIVDVYTVEQLKVKALKSEGKADPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNTCTICNQDSSRLKSFFLSFDVLVDLTDHTGTLHSCSLSGSIAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPTEASRNLARQGHT", "length": 470 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W3M9-1", "protein_name": "Protein hold'em", "gene_name": "hdm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARRIKFQRLAEMRPTMTRFSTVALIVSKSSPNIFYDKMSGTERGVLSLTIRDSPNHLTNCKCWGQRDCVDEYAAMLQIGHVVDIVGAKVMSIPFAAPGEQRYQPQATVSCALVVNEGSGYVVRHDNDDFGQITILQQLLHQPIRPLGAVLKLADVRSGLGFPDKIITTNVNLLVVVAAVRPVRQIKRKLQGPLSEVQELLQCLEVIVIDASYPEGMLLSVWQPDWIQRAQQWQPRRTVLHLIDVRVSYSNFHRSLVLSHSNCTLICENPQAAGDDCRLLLAFAATVPLTTFSGCDQAELDNMPAVASIQAQMTVRQIYSRAEGELQDPSIHQFTAVLYGMVTKFDLDGLTSHVNRKCIACQQHIPRNLQDCASDACQQYFSLDNDEPRSISYFNINIHLSDQTGTLVEARLAGHPAERILGLRAEDFERLAEREKSELKWRFLLKYFEVRLMIKKPVGVRNHLVIVVVDMQAIPLEKLVANMVVF", "length": 486 }, "evidence": [ { "id": "A0A8V0ZEN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "single-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "female meiosis I", "id": "GO:0007144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN7" }, { "id": "PF24903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MEIOB-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 145, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZES9-1", "uniprot_ac": "A0A8V0ZES9", "uniprot_id": "A0A8V0ZES9_CHICK", "mass": { "chemical_mass": 78613.0, "monoisotopic_mass": 78613.0 }, "refseq": { "ac": "NP_001026219", "name": "denticleless protein homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" }, "gene_names": [ { "name": "DTL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZES9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ] }, { "name": "CDT2", "type": "synonym", "evidence": [ { "id": "NP_001026219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" } ] }, { "name": "DTL", "type": "synonym", "evidence": [ { "id": "NP_001026219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" } ] } ], "protein_names": [ { "name": "Denticleless E3 ubiquitin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZES9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9/entry#names_and_taxonomy" } ] }, { "name": "denticleless homolog", "type": "synonym", "evidence": [ { "id": "NP_001026219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" } ] }, { "name": "denticleless protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001026219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720316.1, SRR13267649.199091.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001026219.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DTL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9", "locus": { "chromosome": "3", "start_pos": 21713552, "end_pos": 21738199, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020574", "url": "https://www.ensembl.org/id/ENSGALG00010020574" } ] } } ], "crossref": [ { "id": "A0A8V0ZES9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZES9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421373", "url": "https://www.ncbi.nlm.nih.gov/gene/421373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421373", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHSQFEK", "url": "https://omabrowser.org/oma/group/PHSQFEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7X6", "url": "https://www.orthodb.org/?gene=A0A8V0Z7X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZES9", "url": "https://www.orthodb.org/?gene=A0A8V0ZES9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22852", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22852", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22852:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22852:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCRALLLRAAGHRQSSPLPLQHLLDGYRCSREDDHLSYGEIGMPVPPFGCSFSAAPNFEHVLAVANEEGFVRLYDTEAQNTTKLISKEWQAHSNAVFDLAWVPGEHRIVTASGDQTAKVWDVRAGELLGICKGHQCSLKSVAFSRFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNVVDRQTPSKLRKKRQNLRGLAPLVDFQQSVTVVLLQDEHTLISAGAVDGVIKVWDLRKNYAAYRQDPVPSKSFFYPGTSTRKLGYSSLVLDSTGANLFANCTDDSIYMFNMASLKTFPVAVFSGHQNSTFYIKSSISPDDQFLVSGSSDCNAYIWKVSEPSLPPRILVGHSQEVTSIAWCPSDFTKIATCSDDNTVRIWRLQHYPEEEKSVSNKAKLVGWVTQKKPEEQRGAGRSASPQSTPAKAFSVGSPCASSPRPAACAPSYSGDLPLSTNTPTVSLKTQMATACTPAKLSGASPRTSPKLVPSSKMSIKHWIARTPCSSPEVGKKTPSPRKALAEVTQSLLETSSTPKAQHSQAEKRAKRRLDCSKEDEAGQKCLQDCSCVTELDHVAKKSKLNLCHLAAGQRACDEGSLSLADLDNEHEDSTHSPKELSFPGSLVNPSGTQTPPPVLQSPCERDSDVVDKENSSPERKNWLSALGEKLRTGKAGSPPSSYTSSAKRQEAAVVTTSPKTAVNTSVSMRKICTYFHRKPQN", "length": 720, "header": "tr|A0A8V0ZES9-1|A0A8V0ZES9_CHICK Isoform 1 of Denticleless E3 ubiquitin OS=Gallus gallus OX=9031 GN=DTL PE=3 SV=1 CANONICAL=A0A8V0ZES9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9/entry#A0A8V0Z7X6-1", "sequence": { "sequence": "MLCRALLLRAAGHRQSSPLPLQHLLDGYRCSREDDHLSYGEIGMPVPPFGCSFSAAPNFEHVLAVANEEGFVRLYDTEAQNTTKLISKEWQAHSNAVFDLAWVPGEHRIVTASGDQTAKVWDVRAGELLGICKGHQCSLKSVAFSRFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNVVDRQTPSKLRKKRQNLRGLAPLVDFQQSVTVVLLQDEHTLISAGAVDGVIKVWDLRKNYAAYRQDPVPSKSFFYPGTSTRKLGYSSLVLDSTGANLFANCTDDSIYMFNMASLKTFPVAVFSGHQNSTFYIKSSISPDDQFLVSGSSDCNAYIWKVRRLGGTQVCCPRMCLGHSPNALILIWRLQHYPEEEKSVSNKAKLVGWVTQKKPEEQRGAGRSASPQSTPAKAFSVGSPCASSPRPAACAPSYSGDLPLSTNTPTVSLKTQMATACTPAKLSGASPRTSPKLVPSSKMSIKHWIARTPCSSPEVGKKTPSPRKALAEVTQSLLETSSTPKAQHSQAEKRAKRRLDCSKEDEAGQKCLQDCSCVTELDHVAKKSKLNLCHLAAGQRACDEGSLSLADLDNEHEDSTHSPKELSFPGSLVNPSGTQTPPPVLQSPCERDSDVVDKENSSPERKNWLSALGEKLRTGKAGSPPSSYTSSAKRQEAAVVTTSPKTAVNTSVSMRKICTYFHRKPQN", "length": 704, "header": "tr|A0A8V0Z7X6-1|A0A8V0ZES9_CHICK Computationally mapped isoform of Denticleless E3 ubiquitin OS=Gallus gallus OX=9031 GN=DTL PE=3 SV=1 CANONICAL=A0A8V0ZES9-1" }, "locus": { "chromosome": "3", "start_pos": 21738170, "end_pos": 21716777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049671.1", "url": "https://www.ensembl.org/id/ENSGALT00010049671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029344.1", "url": "https://www.ensembl.org/id/ENSGALP00010029344.1" } ] } }, { "isoform_ac": "A0A8V0ZES9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9/entry#A0A8V0ZES9-1", "sequence": { "sequence": "MLCRALLLRAAGHRQSSPLPLQHLLDGYRCSREDDHLSYGEIGMPVPPFGCSFSAAPNFEHVLAVANEEGFVRLYDTEAQNTTKLISKEWQAHSNAVFDLAWVPGEHRIVTASGDQTAKVWDVRAGELLGICKGHQCSLKSVAFSRFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNVVDRQTPSKLRKKRQNLRGLAPLVDFQQSVTVVLLQDEHTLISAGAVDGVIKVWDLRKNYAAYRQDPVPSKSFFYPGTSTRKLGYSSLVLDSTGANLFANCTDDSIYMFNMASLKTFPVAVFSGHQNSTFYIKSSISPDDQFLVSGSSDCNAYIWKVSEPSLPPRILVGHSQEVTSIAWCPSDFTKIATCSDDNTVRIWRLQHYPEEEKSVSNKAKLVGWVTQKKPEEQRGAGRSASPQSTPAKAFSVGSPCASSPRPAACAPSYSGDLPLSTNTPTVSLKTQMATACTPAKLSGASPRTSPKLVPSSKMSIKHWIARTPCSSPEVGKKTPSPRKALAEVTQSLLETSSTPKAQHSQAEKRAKRRLDCSKEDEAGQKCLQDCSCVTELDHVAKKSKLNLCHLAAGQRACDEGSLSLADLDNEHEDSTHSPKELSFPGSLVNPSGTQTPPPVLQSPCERDSDVVDKENSSPERKNWLSALGEKLRTGKAGSPPSSYTSSAKRQEAAVVTTSPKTAVNTSVSMRKICTYFHRKPQN", "length": 720, "header": "tr|A0A8V0ZES9-1|A0A8V0ZES9_CHICK Isoform 1 of Denticleless E3 ubiquitin OS=Gallus gallus OX=9031 GN=DTL PE=3 SV=1 CANONICAL=A0A8V0ZES9-1" }, "locus": { "chromosome": "3", "start_pos": 21738170, "end_pos": 21716777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049669.1", "url": "https://www.ensembl.org/id/ENSGALT00010049669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029343.1", "url": "https://www.ensembl.org/id/ENSGALP00010029343.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 427, "start_aa": "Thr", "end_pos": 427, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr427", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421373", "resource": "KEGG Pathway" }, { "id": "R-GGA-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZER4-1", "protein_name": "Denticleless protein homolog", "gene_name": "Dtl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSVWRGVWRPGLAVAGVGGKTVSRCGGRKRRLRRNLGAISSAFSSAESSPQDEMLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYRCSCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTSKKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELMGTCKGHQCSLKSVAFSKFQKAVFCTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPSVDSQQSVTVVLFQDENTVVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPLAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPEGDKHSIVGWTSQKKKEVKAGPVSAPNSLSTPAKAPRSQCSPSASSPSSARTPSCAGDLPLPSNTSTFSVKTTPVTTRSPVSRRGSSSSVSPKPPSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVESLHLDLCCLSGTQEVLSQDSAGPTKSSKTEGTGTSISEPPSPVSPFASEGCGPLPLPLGPCGEGSEMVGKENSSPENKNWLLAMAAKHKAENSSPRSPSSQTPSSRRQSRKTSPGPVTITPNSMRKICTYFRRKTQDDFCSPEHSTEL", "length": 783 }, "evidence": [ { "id": "A0A8V0ZES9", "url": "https://omabrowser.org/oma/group/A0A8V0ZES9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TLR7-1", "protein_name": "Denticleless protein homolog", "gene_name": "Dtl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYQCNCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTSKKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVRAGELMGTCKGHQCSLKSVAFPKFQKAVFSTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPAVDSQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPVAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGDKHSIVGWTSQKKKEVKACPVTVPSSQSTPAKAPRAKSSPSISSPSSAACTPSCAGDLPLPSSTPTFSVKTTPATTRSSVSRRGSISSVSPKPLSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQAESLRLDLCCLSGTQEVLSQDSEGPTKSSKTEGAGTSISEPPSPVSPYASEGCGPLPLPLRPCGEGSEMVGKENSSPENKNWLLAIAAKRKAENSSPRSPSSQTPSSRRQSGKTSPGPVTITPSSMRKICTYFRRKTQDDFCSPEHSTEL", "length": 729 }, "evidence": [ { "id": "A0A8V0ZES9", "url": "https://omabrowser.org/oma/group/A0A8V0ZES9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZJ0-1", "protein_name": "Denticleless protein homolog", "gene_name": "DTL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGLVTVTSSQSTPAKAPRAKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPINRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQAEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENKNWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKKLPSPVTITPSSMRKICTYFHRKSQEDFCGPEHSTEL", "length": 730 }, "evidence": [ { "id": "A0A8V0ZES9", "url": "https://omabrowser.org/oma/group/A0A8V0ZES9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "Cul4B-RING E3 ubiquitin ligase complex", "id": "GO:0031465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 427 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 702, "end_pos": 704 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDQ8-1", "uniprot_ac": "A0A8V0ZDQ8", "uniprot_id": "A0A8V0ZDQ8_CHICK", "mass": { "chemical_mass": 90166.0, "monoisotopic_mass": 90166.0 }, "refseq": {}, "gene_names": [ { "name": "PARP9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ] } ], "protein_names": [ { "name": "Poly(ADP-ribose) polymerase family member 9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8", "locus": { "chromosome": "7", "start_pos": 27887995, "end_pos": 27879233, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020584", "url": "https://www.ensembl.org/id/ENSGALG00010020584" } ] } } ], "crossref": [ { "id": "A0A8V0ZDQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02903", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02903", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424269", "url": "https://www.ncbi.nlm.nih.gov/gene/424269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Z7Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHPPPGPTLLLLEVHPSKQSETPKDESGPGPRMDEGSVMIPVNKDTYEALKKRENDLRNLVYKKFACTLTCTKRAAEVYRKVLGEGIHLLVYKDDLTSHKADAVVNAANESLEHSGALALALLNAGGPEIAEESRNFIRKHGKVPTGKIAVTGGGKLPCKKIIHAIGPIWYPSEKEKCCVLLEEAVVNVLKYASDPKNNIKSVAIPAVSSGVFGFPVNLCAQVIVMSIKLFVETQPSCLKEIHLVNICEQTVAEIKRACEMILGEGSSLQETVPASLSLPVPVIKHGNIRLRVIKGYLEKIRTTAIVSSVSSDGEFCSQISTAMLQKAGSTLQAEILSQLKHLHSSKELIVTSGYNLPCEFVLHVLWPCFNHVVLLCEQLKEIVNRCLYFVRNYPLPSIAFPEKNWSLMLPVAIVAEIMIEEVLDFARKYPETKIDVQFVLHPDDDTTYQVFQEKMNLAASKLENNNRSDYLSTESSSQGRKETTYNKMAIELQGRTHFALKAAELWVQSLVQTQKSHSAVIENNYIFSLGKKEYTELSRVKYSNVSMSEKVKDGKASLEFHGPPDAVIDAVLTTEKLLLFMQEQTTAKQEELLRLIGQPDTDQLSEGHLDKTNTTKQFQMLQVDSHLQAFKDRQKQFERTGLHILKIEKIHNPLLSAAFQQTKKNLEQKGVTSKGTHKLYQRVPAQFCTLVCQTGFHRIYSPPPDQRYGAGIYFKRNPNSLIEDDGKKETESKIYVFEADVLTGLYTKGKPSYIMPPAVEGDASMLYDSLVDDINNPDTFVICNSLQALPCYLLTCSQVKESPMDL", "length": 808, "header": "tr|A0A8V0ZDQ8-1|A0A8V0ZDQ8_CHICK Isoform 1 of Poly(ADP-ribose) polymerase family member 9 OS=Gallus gallus OX=9031 GN=PARP9 PE=1 SV=1 CANONICAL=A0A8V0ZDQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8/entry#A0A8V0Z7Y1-1", "sequence": { "sequence": "MWSSKTLLCMYKKLCQWFIGSDFILFYILGPRMDEGSVMIPVNKDTYEALKKRENDLRNLVYKKFACTLTCTKRAAEVYRKVLGEGIHLLVYKDDLTSHKADAVVNAANESLEHSGALALALLNAGGPEIAEESRNFIRKHGKVPTGKIAVTGGGKLPCKKIIHAIGPIWYPSEKEKCCVLLEEAVVNVLKYASDPKNNIKSVAIPAVSSGVFGFPVNLCAQVIVMSIKLFVETQPSCLKEIHLVNICEQTVAEIKRACEMILGEGSSLQETVPASLSLPVPVIKHGNIRLRVIKGYLEKIRTTAIVSSVSSDGEFCSQISTAMLQKAGSTLQAEILSQLKHLHSSKELIVTSGYNLPCEFVLHVLWPCFNHVVLLCEQLKEIVNRCLYFVRNYPLPSIAFPEKNWSLMLPVAIVAEIMIEEVLDFARKYPETKIDVQFVLHPDDDTTYQVFQEKMNLAASKLENNNRSDYLSTESSSQGRKETTYNKMAIELQGRTHFALKAAELWVQSLVQTQKSHSAVIENNYIFSLGKKEYTELSRVKYSNVSMSEKVKDGKASLEFHGPPDAVIDAVLTTEKLLLFMQEQTTAKQEELLRLIGQPDTDQLSEGHLDKTNTTKQFQMLQVDSHLQAFKDRQKQFERTGLHILKIEKIHNPLLSAAFQQTKKNLEQKGVTSKGTHKLYQRVPAQFCTLVCQTGFHRIYSPPPDQRYGAGIYFKRNPNSLIEDDGKKETESKIYVFEADVLTGLYTKGKPSYIMPPAVEGDASMLYDSLVDDINNPDTFVICNSLQALPCYLLTCSQVKESPMDL", "length": 807, "header": "tr|A0A8V0Z7Y1-1|A0A8V0ZDQ8_CHICK Computationally mapped isoform of Poly(ADP-ribose) polymerase family member 9 OS=Gallus gallus OX=9031 GN=PARP9 PE=1 SV=1 CANONICAL=A0A8V0ZDQ8-1" }, "locus": { "chromosome": "7", "start_pos": 27886384, "end_pos": 27880893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049680.1", "url": "https://www.ensembl.org/id/ENSGALT00010049680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029349.1", "url": "https://www.ensembl.org/id/ENSGALP00010029349.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8/entry#A0A8V0ZDQ8-1", "sequence": { "sequence": "MPHPPPGPTLLLLEVHPSKQSETPKDESGPGPRMDEGSVMIPVNKDTYEALKKRENDLRNLVYKKFACTLTCTKRAAEVYRKVLGEGIHLLVYKDDLTSHKADAVVNAANESLEHSGALALALLNAGGPEIAEESRNFIRKHGKVPTGKIAVTGGGKLPCKKIIHAIGPIWYPSEKEKCCVLLEEAVVNVLKYASDPKNNIKSVAIPAVSSGVFGFPVNLCAQVIVMSIKLFVETQPSCLKEIHLVNICEQTVAEIKRACEMILGEGSSLQETVPASLSLPVPVIKHGNIRLRVIKGYLEKIRTTAIVSSVSSDGEFCSQISTAMLQKAGSTLQAEILSQLKHLHSSKELIVTSGYNLPCEFVLHVLWPCFNHVVLLCEQLKEIVNRCLYFVRNYPLPSIAFPEKNWSLMLPVAIVAEIMIEEVLDFARKYPETKIDVQFVLHPDDDTTYQVFQEKMNLAASKLENNNRSDYLSTESSSQGRKETTYNKMAIELQGRTHFALKAAELWVQSLVQTQKSHSAVIENNYIFSLGKKEYTELSRVKYSNVSMSEKVKDGKASLEFHGPPDAVIDAVLTTEKLLLFMQEQTTAKQEELLRLIGQPDTDQLSEGHLDKTNTTKQFQMLQVDSHLQAFKDRQKQFERTGLHILKIEKIHNPLLSAAFQQTKKNLEQKGVTSKGTHKLYQRVPAQFCTLVCQTGFHRIYSPPPDQRYGAGIYFKRNPNSLIEDDGKKETESKIYVFEADVLTGLYTKGKPSYIMPPAVEGDASMLYDSLVDDINNPDTFVICNSLQALPCYLLTCSQVKESPMDL", "length": 808, "header": "tr|A0A8V0ZDQ8-1|A0A8V0ZDQ8_CHICK Isoform 1 of Poly(ADP-ribose) polymerase family member 9 OS=Gallus gallus OX=9031 GN=PARP9 PE=1 SV=1 CANONICAL=A0A8V0ZDQ8-1" }, "locus": { "chromosome": "7", "start_pos": 27886384, "end_pos": 27879265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049689.1", "url": "https://www.ensembl.org/id/ENSGALT00010049689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029356.1", "url": "https://www.ensembl.org/id/ENSGALP00010029356.1" } ] } }, { "isoform_ac": "A0A8V0ZEU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8/entry#A0A8V0ZEU3-1", "sequence": { "sequence": "MDEGSVMIPVNKDTYEALKKRENDLRNLVYKKFACTLTCTKRAAEVYRKVLGEGIHLLVYKDDLTSHKADAVVNAANESLEHSGALALALLNAGGPEIAEESRNFIRKHGKVPTGKIAVTGGGKLPCKKIIHAIGPIWYPSEKEKCCVLLEEAVVNVLKYASDPKNNIKSVAIPAVSSGVFGFPVNLCAQVIVMSIKLFVETQPSCLKEIHLVNICEQTVAEIKRACEMILGEGSSLQETVPASLSLPVPVIKHGNIRLRVIKGYLEKIRTTAIVSSVSSDGEFCSQISTAMLQKAGSTLQAEILSQLKHLHSSKELIVTSGYNLPCEFVLHVLWPCFNHVVLLCEQLKEIVNRCLYFVRNYPLPSIAFPEKNWSLMLPVAIVAEIMIEEVLDFARKYPETKIDVQFVLHPDDDTTYQVFQEKMNLAASKLENNNRSDYLSTESSSQGRKETTYNKMAIELQGRTHFALKAAELWVQSLVQTQKSHSAVIENNYIFSLGKKEYTELSRVKYSNVSMSEKVKDGKASLEFHGPPDAVIDAVLTTEKLLLFMQEQTTAKQEELLRLIGQPDTDQLSEGHLDKTNTTKQFQMLQVDSHLQAFKDRQKQFERTGLHILKIEKIHNPLLSAAFQQTKKNLEQKGVTSKGTHKLYQRVPAQFCTLVCQTGFHRIYSPPPDQRYGAGIYFKRNPNSLIEDDGKKETESKIYVFEADVLTGLYTKGKPSYIMPPAVEGDASMLYDSLVDDINNPDTFVICNSLQALPCYLLTCSQVKESPMDL", "length": 775, "header": "tr|A0A8V0ZEU3-1|A0A8V0ZEU3_CHICK Computationally mapped isoform of Poly(ADP-ribose) polymerase family member 9 OS=Gallus gallus OX=9031 GN=PARP9 PE=1 SV=1 CANONICAL=A0A8V0ZDQ8-1" }, "locus": { "chromosome": "7", "start_pos": 27886384, "end_pos": 27880989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049685.1", "url": "https://www.ensembl.org/id/ENSGALT00010049685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029353.1", "url": "https://www.ensembl.org/id/ENSGALP00010029353.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "STAT family protein binding", "id": "GO:0097677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "ADP-D-ribose binding", "id": "GO:0072570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072570", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity", "id": "GO:0140802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "positive regulation of protein localization to nucleus", "id": "GO:1900182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" }, { "name": "positive regulation of type II interferon-mediated signaling pathway", "id": "GO:0060335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" }, { "id": "PS51154", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Macro", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 264, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ8" }, { "id": "PS51059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PARP catalytic", "eco_id": "ECO_0000259", "start_pos": 605, "end_pos": 807, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 615, "end_pos": 617 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDR3-1", "uniprot_ac": "A0A8V0ZDR3", "uniprot_id": "A0A8V0ZDR3_CHICK", "mass": { "chemical_mass": 113692.0, "monoisotopic_mass": 113692.0 }, "refseq": {}, "gene_names": [ { "name": "PALD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ] } ], "protein_names": [ { "name": "Paladin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PALD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3", "locus": { "chromosome": "6", "start_pos": 12254509, "end_pos": 12240374, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020588", "url": "https://www.ensembl.org/id/ENSGALG00010020588" } ] } } ], "crossref": [ { "id": "A0A8V0ZDR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17660", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17660", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7Z1", "url": "https://www.orthodb.org/?gene=A0A8V0Z7Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDR3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z7Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVHMYVPPCVHRKAGCDPGVQQQMQRAGNEPGRKSQRAGAFSHILLLLKHFPCLRSALGHGRLMAVLPGREAAGHSAVPSADSSHFGGWLQGFSFLPFPALMAEKPCWGFSHGGAGPCLEDKGGESLLWMMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRRLRGRWRAQSGAGWPSRGDLV", "length": 999, "header": "tr|A0A8V0ZDR3-1|A0A8V0ZDR3_CHICK Isoform 1 of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#A0A8V0Z7Z1-1", "sequence": { "sequence": "MMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQENTAKRDSCHVLCSPQLVMG", "length": 787, "header": "tr|A0A8V0Z7Z1-1|A0A8V0ZDR3_CHICK Computationally mapped isoform of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "locus": { "chromosome": "6", "start_pos": 12251130, "end_pos": 12242936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049693.1", "url": "https://www.ensembl.org/id/ENSGALT00010049693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029359.1", "url": "https://www.ensembl.org/id/ENSGALP00010029359.1" } ] } }, { "isoform_ac": "A0A8V0ZDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#A0A8V0ZDR3-1", "sequence": { "sequence": "MSVHMYVPPCVHRKAGCDPGVQQQMQRAGNEPGRKSQRAGAFSHILLLLKHFPCLRSALGHGRLMAVLPGREAAGHSAVPSADSSHFGGWLQGFSFLPFPALMAEKPCWGFSHGGAGPCLEDKGGESLLWMMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRRLRGRWRAQSGAGWPSRGDLV", "length": 999, "header": "tr|A0A8V0ZDR3-1|A0A8V0ZDR3_CHICK Isoform 1 of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "locus": { "chromosome": "6", "start_pos": 12253794, "end_pos": 12242384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049696.1", "url": "https://www.ensembl.org/id/ENSGALT00010049696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029361.1", "url": "https://www.ensembl.org/id/ENSGALP00010029361.1" } ] } }, { "isoform_ac": "A0A8V0ZDS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#A0A8V0ZDS0-1", "sequence": { "sequence": "MMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNQGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVLFLARLGCPAHPCSCLSLLTPPGRLQI", "length": 848, "header": "tr|A0A8V0ZDS0-1|A0A8V0ZDS0_CHICK Computationally mapped isoform of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "locus": { "chromosome": "6", "start_pos": 12253239, "end_pos": 12242936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049703.1", "url": "https://www.ensembl.org/id/ENSGALT00010049703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029366.1", "url": "https://www.ensembl.org/id/ENSGALP00010029366.1" } ] } }, { "isoform_ac": "A0A8V0ZDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#A0A8V0ZDS4-1", "sequence": { "sequence": "MMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNQGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQGRSGKDEQERRLLRLRSLQYLERYIYLILFNSYLHLEKKDSWQRPFSLWMREVAAVAGVYEVLDGLGFPELEQLEDEEPLRRLRGRWRAQSGAGWPSRGDLV", "length": 870, "header": "tr|A0A8V0ZDS4-1|A0A8V0ZDS4_CHICK Computationally mapped isoform of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "locus": { "chromosome": "6", "start_pos": 12253794, "end_pos": 12242936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049708.1", "url": "https://www.ensembl.org/id/ENSGALT00010049708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029371.1", "url": "https://www.ensembl.org/id/ENSGALP00010029371.1" } ] } }, { "isoform_ac": "A0A8V0ZEW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3/entry#A0A8V0ZEW8-1", "sequence": { "sequence": "MMGTTASTAQQTVSASAFESVHGIGTMEDQRSLSIHSFQTLGLHNSKAKSIITNKVAPVVITYNCREEFQIHDDLLKANYTVGRISDATLEHYLVQGKYFMVRDVYSKLDVLNTTASCGAPNFRQAKGGYAVFGMGQPSLGGFKLVLQKLQREGHKECVFFCVREEPVLFLRVESDFVPYTPRGKENLHENLHSLRRGLRVEDLELTIRKEIHDFAQLSEGVYYVYNDIERFRDEPHTVRVQGEEDIHVTEEVYRRPIFLLPTYRYHRLPLPVDGAPLEEQFDAFICFLRESSGLLLRDPSRPPPALLFSCQTGVGRTNLAMALGTLILHHHRGAAPKPDPPHPAKMPPRAKFRVIQSFIEMVPKGQQMVEEVDSVIASCSEMHDMKEAIYESKKKLEGIGEDYQIQGNSTKEYFLQRTLQSLERYFYLIAFNYYLHEQYPLGFALSFSRWMCRHPELYRLQAIMNSSELTITGDLITKGTRVLVVDERFCPDVLSTVKEMSVANFRRVPKMPIYGTAQPSSKALSSVLRYLTDAKRKHSRILWVSLREEVVLEGNEQIYTLREPGSLDQLIPVPVSTPEQLEKLESTLKGDLLKSQKWLEVYLEAEKQMKMFKSCLTTQEIFNQHKSTCQGLTYRRIPIPDFCAPKEQDFDRLLEAMKSALAEDSQTAFVFNCASGRGRTTTAMVIAVLTLWHFNQGIPEMSEEEIVSVPDAKYTKGEFEVVMKVVQLLPDGHRMKKEVDMALDTVSETMTPMHYHLREIIICTYRQVSNAPFCHRADPPEPK", "length": 784, "header": "tr|A0A8V0ZEW8-1|A0A8V0ZEW8_CHICK Computationally mapped isoform of Paladin OS=Gallus gallus OX=9031 GN=PALD1 PE=3 SV=1 CANONICAL=A0A8V0ZDR3-1" }, "locus": { "chromosome": "6", "start_pos": 12250934, "end_pos": 12242936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049711.1", "url": "https://www.ensembl.org/id/ENSGALT00010049711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029373.1", "url": "https://www.ensembl.org/id/ENSGALP00010029373.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF27-1", "uniprot_ac": "A0A8V0ZF27", "uniprot_id": "A0A8V0ZF27_CHICK", "mass": { "chemical_mass": 145150.0, "monoisotopic_mass": 145150.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM66", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27", "locus": { "chromosome": "5", "start_pos": 9451340, "end_pos": 9408047, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020629", "url": "https://www.ensembl.org/id/ENSGALG00010020629" } ] } } ], "crossref": [ { "id": "cd05502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19811", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19811", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423056", "url": "https://www.ncbi.nlm.nih.gov/gene/423056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423056", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z851", "url": "https://www.orthodb.org/?gene=A0A8V0Z851", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF27", "url": "https://www.orthodb.org/?gene=A0A8V0ZF27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25287", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25287", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z851", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z851", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z851-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z851-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIKAIREYHHIYCTVSELLAGNVQRVTVQPDISFPTAMEPLDVLRKCLVCKWDLCRRDPRMLPCLHSFCKDCLPELIQGYSYISTGREIVYEGILSCLACKQTCFARDVVENCFLKDFPTANSAMAKSCSMCKEKRPAHSLCTSCNKWLCSTCTEEHRHGKETGDRFLSVSLKGCTATEEEASELPLLCPVHTQEPLKLFCETCDILTCSSCLLKDHKEHRFRHLDEALQNQRAILENVVTKVEEKKSGIQVSAKQIEDRLLEVKHLYKRVENQIKMAKMVLINEINKRANILLEQLEKITNERRQKLEQQLQGVVVLSAQVEHVQNFVNWAVCSKNSIPFLFSKELIVFQIQRLLETNPDTDIAPPLKIRFTWDPSYWSKQLSNFGGFTMEGGHTSHSDVLLCGNVQGLQTPLYHGHCSPVSQLEPMNSQPHQFPPAPPCPIPVCCSHCLSVPHPNKAQPSHQNISPHQHFRQPPELHQQHFPLQYSMQQRDKEQRGVSQPLKPSQSELEQQSRSESENGSGRMGKHLPSQLQQTVPLGYAVVSHEAQQVHTSHPQPFRSQTALQTSTVQVQLGHLQKIKSNYVQQPPQQQLSPASPPPSQYENAHKQVMQQSLDIMHHQFELEEMKKDLELLLQAQGQSSLQLNQAKPPQHVQQTIVGQINYIVRQPAPIQQQIEDEAQVCENSTELDAQKPAVPLDRSKISSMSQSLDEEVSVSSHSPGTTSQQSTSHPVRKRSASLGIVGFSNELEMELPSRLSRSADPQVQGIATVALGPSPNTRCDCDSPPEPVPSYSLALGRAELSPGVSTTFTPGDVHQGSAKCKLENEDFNTVDHHPENSLATAGQDVVNELSLSMQNILEEPINLSVKKSQRCTSPSELLSNNSLLPVNARMRPLRNEEDSNNCEKEHFEMVMKGNQNVSACLGELKIPYVRLERLKICASESGELPVFKLQPQESGQEGNFLLIIEHGTQSSRMAIKINKGGSPEGLKSEEENSDDRKFLITQAAGQIKSPPADAPSVDQKLTNGTSITKKSPVTQEVNTIENEDFCAVCLNGGELLCCDHCPKVFHLSCHVPALLSFPVGEWVCTLCRNPMKPEVEYDCENTRYAHSYNAQYGLDDYDQKKCEKLVLSLFCSSMSLPFHEPVSPLARHYYQIIKRPMDLSIIRKKLQKKDKFHYSAPEELVTDVRLMFWNCAKFNYPDSEVAEAGRCLDVFFEGKLKEIYPDRHFPSAQQDDSDCEELESQNSKMPPQDFHWPSHEQECAQPKKRRRHTVRLQKQKHLVAKWPPC", "length": 1287, "header": "tr|A0A8V0ZF27-1|A0A8V0ZF27_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM66 PE=4 SV=1 CANONICAL=A0A8V0ZF27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z851-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27/entry#A0A8V0Z851-1", "sequence": { "sequence": 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"length": 1271, "header": "tr|A0A8V0Z851-1|A0A8V0ZF27_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM66 PE=4 SV=1 CANONICAL=A0A8V0ZF27-1" }, "locus": { "chromosome": "5", "start_pos": 9451135, "end_pos": 9410395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049791.1", "url": "https://www.ensembl.org/id/ENSGALT00010049791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029421.1", "url": "https://www.ensembl.org/id/ENSGALP00010029421.1" } ] } }, { "isoform_ac": "A0A8V0ZF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF27/entry#A0A8V0ZF27-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZF70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFAF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70", "locus": { "chromosome": "12", "start_pos": 11826383, "end_pos": 11828034, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020653", "url": "https://www.ensembl.org/id/ENSGALG00010020653" } ] } } ], "crossref": [ { "id": "A0A8V0ZF70", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF70", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z892", "url": "https://www.orthodb.org/?gene=A0A8V0Z892", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF70", "url": "https://www.orthodb.org/?gene=A0A8V0ZF70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21192:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21192:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04430", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04430", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z892", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z892", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z892-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z892-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAALRRLCRAGPRAVTGAPRRGHRLTPSDDEMYQRTRVTVLQPESPNVAFIEGYSGRGFSISGSVVVGPCAVLPRAILQWNVGSHRDISLQSLALFRLLEPRIAERVRHLQLPDEREAPHGRRPHPPAGRIHGAHSAARGHGLSASALTHPQRRGRPTPSAAAAGGETLQDGRWEPNCWLSAASRCWSAVGPCLGAARGEYT", "length": 203, "header": "tr|A0A8V0ZF70-1|A0A8V0ZF70_CHICK Isoform 1 of NADH:ubiquinone oxidoreductase complex assembly factor 3 OS=Gallus gallus OX=9031 GN=NDUFAF3 PE=4 SV=1 CANONICAL=A0A8V0ZF70-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z892-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70/entry#A0A8V0Z892-1", "sequence": { "sequence": "MAAALRRLCRAGPRAVTGAPRRGHRLTPSDDEMYQRTRVTVLQPESPNVAFIEGYSGRGFSISGSVVVGPCAVLPRAILQWNSLALFRLLEPRIEILVLGTGDRVEQLHPAVLRQMRLCGIAVEVQDTPNACATFNFLTSEKRLTAAGLIPPRGAYTGLTALPAATD", "length": 167, "header": "tr|A0A8V0Z892-1|A0A8V0ZF70_CHICK Computationally mapped isoform of NADH:ubiquinone oxidoreductase complex assembly factor 3 OS=Gallus gallus OX=9031 GN=NDUFAF3 PE=4 SV=1 CANONICAL=A0A8V0ZF70-1" }, "locus": { "chromosome": "12", "start_pos": 11827993, "end_pos": 11827104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049873.1", "url": "https://www.ensembl.org/id/ENSGALT00010049873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029462.1", "url": "https://www.ensembl.org/id/ENSGALP00010029462.1" } ] } }, { "isoform_ac": "A0A8V0ZF70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70/entry#A0A8V0ZF70-1", "sequence": { "sequence": "MAAALRRLCRAGPRAVTGAPRRGHRLTPSDDEMYQRTRVTVLQPESPNVAFIEGYSGRGFSISGSVVVGPCAVLPRAILQWNVGSHRDISLQSLALFRLLEPRIAERVRHLQLPDEREAPHGRRPHPPAGRIHGAHSAARGHGLSASALTHPQRRGRPTPSAAAAGGETLQDGRWEPNCWLSAASRCWSAVGPCLGAARGEYT", "length": 203, "header": "tr|A0A8V0ZF70-1|A0A8V0ZF70_CHICK Isoform 1 of NADH:ubiquinone oxidoreductase complex assembly factor 3 OS=Gallus gallus OX=9031 GN=NDUFAF3 PE=4 SV=1 CANONICAL=A0A8V0ZF70-1" }, "locus": { "chromosome": "12", "start_pos": 11827993, "end_pos": 11826925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049869.1", "url": "https://www.ensembl.org/id/ENSGALT00010049869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029461.1", "url": "https://www.ensembl.org/id/ENSGALP00010029461.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZF70" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 159 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF98-1", "uniprot_ac": "A0A8V0ZF98", "uniprot_id": "A0A8V0ZF98_CHICK", "mass": { "chemical_mass": 37689.0, "monoisotopic_mass": 37689.0 }, "refseq": {}, "gene_names": [ { "name": "UBTD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98" } ] } ], "protein_names": [ { "name": "Ubiquitin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBTD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98", "locus": { "chromosome": "6", "start_pos": 23114809, "end_pos": 23119251, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020667", "url": "https://www.ensembl.org/id/ENSGALG00010020667" } ] } } ], "crossref": [ { "id": "A0A8V0ZF98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF98", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17120", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17120", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8B5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF98", "url": "https://www.orthodb.org/?gene=A0A8V0ZF98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLJ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZLJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13609", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13609", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAASAPLPHLVPPPEAPGRGGTPGGGARAGVRRRGRDRSAGRSGRAHVGGAPRGAAAGSGGRDGAVTCAPGEAGRGEGRLWRRGGSGVRSRAVRSRDAGARGRVRCGAGPAPCRAARAAAAVGEPPPWAAAWGGSAGSGPPPGAPRKRAGRNEPLKKERPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAVEANDHSLAQAILDGASITLPHGSLTECYDELGNRYQLPVYCLAPPVNLILERGEEEAAEPAEPPPNARREFALKVRLSTGKDLRLSASMADTIGQLKKQLQAQEGIDLAWQRWFFSGKLLTDRTRLQETKIQKDFVVQVIVNQPLPPRN", "length": 354, "header": "tr|A0A8V0ZF98-1|A0A8V0ZF98_CHICK Isoform 1 of Ubiquitin domain containing 1 OS=Gallus gallus OX=9031 GN=UBTD1 PE=4 SV=1 CANONICAL=A0A8V0ZF98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98/entry#A0A8V0Z8B5-1", "sequence": { "sequence": "MWEQPCSELSCARAGRNEPLKKERPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAVEANDHSLAQAILDGASITLPHGSLTECYDELGNRYQLPVYCLAPPVNLILERGEEEAAEPAEPPPNARREFALKVRLSTGKDLRLSASMADTIGQLKKQLQAQEGIDLAWQRWFFSGKLLTDRTRLQETKIQKDFVVQVIVNQPLPPRN", "length": 218, "header": "tr|A0A8V0Z8B5-1|A0A8V0ZF98_CHICK Computationally mapped isoform of Ubiquitin domain containing 1 OS=Gallus gallus OX=9031 GN=UBTD1 PE=4 SV=1 CANONICAL=A0A8V0ZF98-1" }, "locus": { "chromosome": "6", "start_pos": 23117822, "end_pos": 23115136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049921.1", "url": "https://www.ensembl.org/id/ENSGALT00010049921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029482.1", "url": "https://www.ensembl.org/id/ENSGALP00010029482.1" } ] } }, { "isoform_ac": "A0A8V0ZF98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98/entry#A0A8V0ZF98-1", "sequence": { "sequence": "MRAASAPLPHLVPPPEAPGRGGTPGGGARAGVRRRGRDRSAGRSGRAHVGGAPRGAAAGSGGRDGAVTCAPGEAGRGEGRLWRRGGSGVRSRAVRSRDAGARGRVRCGAGPAPCRAARAAAAVGEPPPWAAAWGGSAGSGPPPGAPRKRAGRNEPLKKERPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAVEANDHSLAQAILDGASITLPHGSLTECYDELGNRYQLPVYCLAPPVNLILERGEEEAAEPAEPPPNARREFALKVRLSTGKDLRLSASMADTIGQLKKQLQAQEGIDLAWQRWFFSGKLLTDRTRLQETKIQKDFVVQVIVNQPLPPRN", "length": 354, "header": "tr|A0A8V0ZF98-1|A0A8V0ZF98_CHICK Isoform 1 of Ubiquitin domain containing 1 OS=Gallus gallus OX=9031 GN=UBTD1 PE=4 SV=1 CANONICAL=A0A8V0ZF98-1" }, "locus": { "chromosome": "6", "start_pos": 23119087, "end_pos": 23115136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049925.1", "url": "https://www.ensembl.org/id/ENSGALT00010049925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029486.1", "url": "https://www.ensembl.org/id/ENSGALP00010029486.1" } ] } }, { "isoform_ac": "A0A8V0ZLJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98/entry#A0A8V0ZLJ0-1", "sequence": { "sequence": "MMLVAPSSVILTTSFRLVVSTVPRAGRNEPLKKERPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAVEANDHSLAQAILDGASITLPHGSLTECYDELGNRYQLPVYCLAPPVNLILERGEEEAAEPAEPPPNARREFALKVRLSTGKDLRLSASMADTIGQLKKQLQAQEGIDLAWQRWFFSGKLLTDRTRLQETKIQKDFVVQVIVNQPLPPRN", "length": 229, "header": "tr|A0A8V0ZLJ0-1|A0A8V0ZLJ0_CHICK Computationally mapped isoform of Ubiquitin domain containing 1 OS=Gallus gallus OX=9031 GN=UBTD1 PE=4 SV=1 CANONICAL=A0A8V0ZF98-1" }, "locus": { "chromosome": "6", "start_pos": 23117052, "end_pos": 23115136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049915.1", "url": "https://www.ensembl.org/id/ENSGALT00010049915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029478.1", "url": "https://www.ensembl.org/id/ENSGALP00010029478.1" } ] } }, { "isoform_ac": "A0A8V0ZLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98/entry#A0A8V0ZLJ3-1", "sequence": { "sequence": "MGGCVGRQRRERPSAGSPPQESSPSCPRSVPMVSLMRPHHRTLGPVRWGQRSRCRNSPRCAPAFPSGPRQAPGGRHGRNEPLKKERPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAVEANDHSLAQAILDGASITLPHGSLTECYDELGNRYQLPVYCLAPPVNLILERGEEEAAEPAEPPPNARREFALKVRLSTGKDLRLSASMADTIGQLKKQLQAQEGIDLAWQRWFFSGKLLTDRTRLQETKIQKDFVVQVIVNQPLPPRN", "length": 280, "header": "tr|A0A8V0ZLJ3-1|A0A8V0ZLJ3_CHICK Computationally mapped isoform of Ubiquitin domain containing 1 OS=Gallus gallus OX=9031 GN=UBTD1 PE=4 SV=1 CANONICAL=A0A8V0ZF98-1" }, "locus": { "chromosome": "6", "start_pos": 23118704, "end_pos": 23115136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049922.1", "url": "https://www.ensembl.org/id/ENSGALT00010049922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029483.1", "url": "https://www.ensembl.org/id/ENSGALP00010029483.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 23, "start_aa": "Thr", "end_pos": 23, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr23", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF98" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 351, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 23 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE53-1", "uniprot_ac": "A0A8V0ZE53", "uniprot_id": "A0A8V0ZE53_CHICK", "mass": { "chemical_mass": 59330.0, "monoisotopic_mass": 59330.0 }, "refseq": {}, "gene_names": [ { "name": "WDR6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53" } ] } ], "protein_names": [ { "name": "tRNA (34-2'-O)-methyltransferase regulator WDR6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of substrate tRNAs. Required for the correct positioning of the substrate tRNA for methylation. Required to suppress amino acid starvation-induced autophagy. Enhances the STK11/LKB1-induced cell growth suppression activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53#function" }, { "database": "UniProtKB", "id": "ARBA00045751", "url": "https://www.uniprot.org/uniprotkb/ARBA00045751#function" }, { "database": "UniProtKB", "id": "A0A8V0Z8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZE53", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE53", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE53", "url": "https://www.orthodb.org/?gene=A0A8V0ZE53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14344:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14344:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8C2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GDAAEDAVGTPGRGAGTGVTSVTCHGDYIYSTGRDGCYRQLCLRDQQLEVLQKHRPCKGLQWIEELRFTPGGDLLVLGFHADDFVVWSTRSGVNLHCVPCGGGHRSWSYYSSPEADAFAYVKRGDVMLYHSQAEPCEQRVLLASLHGREITCVRHLGAVRVPGSHPVNIFITGSEDTTACVLTLSELTRAAVPLARLSDHISSVRALALADTALHDGTQLCSLLFSAGGRAQIECYRLQCAVDLGAEGTVSCQVAHVASHRLDEHWDRMKNRHKLVKMDPETRYMSLSVVCGTNSEQLPMPCTFLVAACSDGSVRLFVLLEAAQKLLLVAESFHHQRCVLKVEAFLHTRAEERKHLLCSAATDGSVAFWDITKMRPLALGTPLLTVMAHSCGVNSLHIQELPEGQFLVASGSDDGSIHVCLLEVTRGDDKAEPGTCLHILEHVARPCTHAAHVTGIRVLRPDLVLSASVDQRLTLWQLSWDSLEELSTTFFHVPDLAELDCWEVAEAGGERRWYCVLCGQGLELLRCAALDTHSKLQSQGAAQ", "length": 543, "header": "tr|A0A8V0ZE53-1|A0A8V0ZE53_CHICK Isoform 1 of tRNA (34-2'-O)-methyltransferase regulator WDR6 OS=Gallus gallus OX=9031 GN=WDR6 PE=3 SV=1 CANONICAL=A0A8V0ZE53-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53/entry#A0A8V0Z8C2-1", "sequence": { "sequence": "ICQVAHVASHRLDEHWDRMKNRHKLVKMDPETRYMSLSVVCGTNSEQLPMPCTFLVAACSDGSVRLFVLLEAAQKLLLVAESFHHQRCVLKVEAFLHTRAEERKHLLCSAATDGSVAFWDITKMRPLALGTPLLTVMAHSCGVNSLHIQELPEGQFLVASGSDDGSIHVCLLEVTRGDDKAEPGTCLHILEHVARPCTHAAHVTGIRVLRPDLVLSASVDQRLTLWQLSWDSLEELSTTFFHVPDLAELDCWEVAEAGGERRWYCVLCGQGLELLRCAALDTHSKLQSQGAAQ", "length": 293, "header": "tr|A0A8V0Z8C2-1|A0A8V0ZE53_CHICK Computationally mapped isoform of tRNA (34-2'-O)-methyltransferase regulator WDR6 OS=Gallus gallus OX=9031 GN=WDR6 PE=3 SV=1 CANONICAL=A0A8V0ZE53-1" }, "locus": { "chromosome": "12", "start_pos": 11837458, "end_pos": 11835599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049937.1", "url": "https://www.ensembl.org/id/ENSGALT00010049937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029492.1", "url": "https://www.ensembl.org/id/ENSGALP00010029492.1" } ] } }, { "isoform_ac": "A0A8V0ZE53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53/entry#A0A8V0ZE53-1", "sequence": { "sequence": "GDAAEDAVGTPGRGAGTGVTSVTCHGDYIYSTGRDGCYRQLCLRDQQLEVLQKHRPCKGLQWIEELRFTPGGDLLVLGFHADDFVVWSTRSGVNLHCVPCGGGHRSWSYYSSPEADAFAYVKRGDVMLYHSQAEPCEQRVLLASLHGREITCVRHLGAVRVPGSHPVNIFITGSEDTTACVLTLSELTRAAVPLARLSDHISSVRALALADTALHDGTQLCSLLFSAGGRAQIECYRLQCAVDLGAEGTVSCQVAHVASHRLDEHWDRMKNRHKLVKMDPETRYMSLSVVCGTNSEQLPMPCTFLVAACSDGSVRLFVLLEAAQKLLLVAESFHHQRCVLKVEAFLHTRAEERKHLLCSAATDGSVAFWDITKMRPLALGTPLLTVMAHSCGVNSLHIQELPEGQFLVASGSDDGSIHVCLLEVTRGDDKAEPGTCLHILEHVARPCTHAAHVTGIRVLRPDLVLSASVDQRLTLWQLSWDSLEELSTTFFHVPDLAELDCWEVAEAGGERRWYCVLCGQGLELLRCAALDTHSKLQSQGAAQ", "length": 543, "header": "tr|A0A8V0ZE53-1|A0A8V0ZE53_CHICK Isoform 1 of tRNA (34-2'-O)-methyltransferase regulator WDR6 OS=Gallus gallus OX=9031 GN=WDR6 PE=3 SV=1 CANONICAL=A0A8V0ZE53-1" }, "locus": { "chromosome": "12", "start_pos": 11838855, "end_pos": 11835599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049939.1", "url": "https://www.ensembl.org/id/ENSGALT00010049939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029494.1", "url": "https://www.ensembl.org/id/ENSGALP00010029494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE84-1", "uniprot_ac": "A0A8V0ZE84", "uniprot_id": "A0A8V0ZE84_CHICK", "mass": { "chemical_mass": 53732.0, "monoisotopic_mass": 53732.0 }, "refseq": { "ac": "NP_001383647", "name": "suppressor of fused homolog isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647" }, "gene_names": [ { "name": "SUFU", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ] }, { "name": "SUFU", "type": "synonym", "evidence": [ { "id": "NP_001383647", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647" } ] } ], "protein_names": [ { "name": "Suppressor of fused homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84/entry#names_and_taxonomy" } ] }, { "name": "suppressor of fused homolog isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001383647", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647" } ] }, { "name": "suppressor of fused homolog", "type": "synonym", "evidence": [ { "id": "NP_001383647", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.10091.1, SRR13267655.221962.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Oct 25, 2021 this sequence version replaced XP_015144027.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383647", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUFU", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84", "locus": { "chromosome": "6", "start_pos": 24054118, "end_pos": 23968880, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018581", "url": "https://www.ensembl.org/id/ENSGALG00010018581" } ] } } ], "crossref": [ { "id": "A0A8V0ZE84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE84", "database": "AlphaFoldDB", "categories": [] }, { "id": "374118", "url": "https://www.ncbi.nlm.nih.gov/gene/374118", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQIVGVT", "url": "https://omabrowser.org/oma/group/CQIVGVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C3", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE74", "url": "https://www.orthodb.org/?gene=A0A8V0ZE74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE84", "url": "https://www.orthodb.org/?gene=A0A8V0ZE84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10928:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10928:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5610780", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610780", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610785", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610785", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383647", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383647", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGTRPGGAAPAGGAGSGSGSSSFPSLFPPGLHGIYGECRRLYPEQPNPLQVTAILKYWLGGPDPLDYVSMYRNIGNPALNVPEHWHYVSFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHAAQQWNGQGILELLRTVPVAGGPWLITDMRRGETIFEIDPHLQQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINAQRQNGLNHDRAPSRKDSLESESSAAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDTAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVERMLEDLEDLNSPEEFKLPKEYSWPEKKLKVSILPDAVFDNPLH", "length": 483, "header": "tr|A0A8V0ZE84-1|A0A8V0ZE84_CHICK Isoform 1 of Suppressor of fused homolog OS=Gallus gallus OX=9031 GN=SUFU PE=3 SV=1 CANONICAL=A0A8V0ZE84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84/entry#A0A8V0Z8C3-1", "sequence": { "sequence": "MTKGSWPAGPPALPGTGTRGRPHSRCLSRRAGSLSRRRTPWRGPAAVTRQGATAQPAAAHARKDGAEPAGLGGPDPLDYVSMYRNIGNPALNVPEHWHYVSFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHAAQQWNGQGILELLRTVPVAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINAQRQNGLNHDRAPSRKDSLESESSAAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDTAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVERMLEDLEDLNSPEEFKLPKEYSWPEKKLKVSILPDAVFDNPLH", "length": 493, "header": "tr|A0A8V0Z8C3-1|A0A8V0ZE84_CHICK Computationally mapped isoform of Suppressor of fused homolog OS=Gallus gallus OX=9031 GN=SUFU PE=3 SV=1 CANONICAL=A0A8V0ZE84-1" }, "locus": { "chromosome": "6", "start_pos": 24051134, "end_pos": 23968927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044974.1", "url": "https://www.ensembl.org/id/ENSGALT00010044974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026860.1", "url": "https://www.ensembl.org/id/ENSGALP00010026860.1" } ] } }, { "isoform_ac": "A0A8V0ZE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84/entry#A0A8V0ZE74-1", "sequence": { "sequence": "MEGTRPGGAAPAGGAGSGSGSSSFPSLFPPGLHGIYGECRRLYPEQPNPLQVTAILKYWFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHAAQQWNGQGILELLRTVPVAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINAQRQNGLNHDRAPSRKDSLESESSAAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDTAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVERMLEDLEDLNSPEEFKLPKEYSWPEKKLKVSILPDAVFDNPLH", "length": 437, "header": "tr|A0A8V0ZE74-1|A0A8V0ZE74_CHICK Computationally mapped isoform of Suppressor of fused homolog OS=Gallus gallus OX=9031 GN=SUFU PE=3 SV=1 CANONICAL=A0A8V0ZE84-1" }, "locus": { "chromosome": "6", "start_pos": 24051134, "end_pos": 23969741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044970.1", "url": "https://www.ensembl.org/id/ENSGALT00010044970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026858.1", "url": "https://www.ensembl.org/id/ENSGALP00010026858.1" } ] } }, { "isoform_ac": "A0A8V0ZE84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84/entry#A0A8V0ZE84-1", "sequence": { "sequence": "MEGTRPGGAAPAGGAGSGSGSSSFPSLFPPGLHGIYGECRRLYPEQPNPLQVTAILKYWLGGPDPLDYVSMYRNIGNPALNVPEHWHYVSFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHAAQQWNGQGILELLRTVPVAGGPWLITDMRRGETIFEIDPHLQQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINAQRQNGLNHDRAPSRKDSLESESSAAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDTAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVERMLEDLEDLNSPEEFKLPKEYSWPEKKLKVSILPDAVFDNPLH", "length": 483, "header": "tr|A0A8V0ZE84-1|A0A8V0ZE84_CHICK Isoform 1 of Suppressor of fused homolog OS=Gallus gallus OX=9031 GN=SUFU PE=3 SV=1 CANONICAL=A0A8V0ZE84-1" }, "locus": { "chromosome": "6", "start_pos": 24051134, "end_pos": 23969741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044983.1", "url": "https://www.ensembl.org/id/ENSGALT00010044983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026868.1", "url": "https://www.ensembl.org/id/ENSGALP00010026868.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5610780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610780", "resource": "Reactome", "description": "Degradation of GLI1 by the proteasome" }, { "id": "R-GGA-5610785", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610785", "resource": "Reactome", "description": "GLI3 is processed to GLI3R by the proteasome" }, { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-GGA-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A606-1", "protein_name": "Suppressor of fused homolog", "gene_name": "Sufu", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELRPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTYDRAPSRKDSLGSDISTAVIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPEEFKLPKEYSWPEKKLKVSILPDVVFDSPLH", "length": 484 }, "evidence": [ { "id": "A0A8V0ZE84", "url": "https://omabrowser.org/oma/group/A0A8V0ZE84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UMX1-1", "protein_name": "Suppressor of fused homolog", "gene_name": "SUFU", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELRPSGAPGPTAPPAPGPTAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINPQRQNGLAHDRAPSRKDSLESDSSTAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPEEFKLPKEYSWPEKKLKVSILPDVVFDSPLH", "length": 484 }, "evidence": [ { "id": "A0A8V0ZE84", "url": "https://omabrowser.org/oma/group/A0A8V0ZE84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VG38-1", "protein_name": "Suppressor of fused homolog", "gene_name": "Su(fu)", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEANLDKKPEVKPPPGLKAIIDHLGQVYPNQPNPLQVTTLLKYWLGGQDPLDYISMYNYPGDVDRNVPPHWHYISFGLSDLHGDERVHLREEGVTRSGMGFELTFRLAKTEIELKQQIENPEKPQRPPTWPANLLQAIGRYCFQTGNGLCFGDNIPWRKSLDGSTTSKLQNLLVAQDPQLGCIDTPTGTVDFCQIVGVFDDELEQASRWNGRGVLNFLRQDMQTGGDWLVTNMDRQMSVFELFPETLLNLQDDLEKQGSDLAGVNADFTFRELKPTKEVKEEVDFQALSEKCANDENNRQLTDTQMKREEPSFPQSMSMSSNSLHKSCPLDFQAQAPNCISLDGIEITLAPGVAKYLLLAIKDRIRHGRHFTFKAQHLALTLVAESVTGSAVTVNEPYGVLGYWIQVLIPDELVPRLMEDFRSAGLDEKCEPKERLELEWPDKNLKLIIDQPEPVLPMSLDAAPLKM", "length": 468 }, "evidence": [ { "id": "A0A8V0ZE84", "url": "https://omabrowser.org/oma/group/A0A8V0ZE84/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0P7-1", "protein_name": "Suppressor of fused homolog", "gene_name": "Sufu", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELRPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVRTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDEEDSRSICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTHDRAPSRKDSLGSDSSTAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPEEFKLPKEYSWPEKKLKVSILPDVVFDSPLH", "length": 484 }, "evidence": [ { "id": "A0A8V0ZE84", "url": "https://omabrowser.org/oma/group/A0A8V0ZE84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" }, { "id": "PF12470", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12470" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Suppressor of fused C-terminal", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 472, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZE84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE84" }, { "id": "PF05076", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Suppressor of fused-like", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 238, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEM3-1", "uniprot_ac": "A0A8V0ZEM3", "uniprot_id": "A0A8V0ZEM3_CHICK", "mass": { "chemical_mass": 84271.0, "monoisotopic_mass": 84271.0 }, "refseq": { "ac": "XP_015152469", "name": "proton-associated sugar transporter A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152469" }, "gene_names": [ { "name": "SLC45A1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ] }, { "name": "SLC45A1", "type": "synonym", "evidence": [ { "id": "XP_015152469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152469" } ] } ], "protein_names": [ { "name": "Proton-associated sugar transporter A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 45 member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3/entry#names_and_taxonomy" } ] }, { "name": "proton-associated sugar transporter A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015152469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152469" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152469" } ] }, { "annotation": "Proton-associated glucose transporter in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q9#function" }, { "database": "UniProtKB", "id": "ARBA00057104", "url": "https://www.uniprot.org/uniprotkb/ARBA00057104#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC45A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3", "locus": { "chromosome": "21", "start_pos": 201771, "end_pos": 213648, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018707", "url": "https://www.ensembl.org/id/ENSGALG00010018707" } ] } } ], "crossref": [ { "id": "A0A8V0ZEM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17313", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17313", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419363", "url": "https://www.ncbi.nlm.nih.gov/gene/419363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419363", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDYYQSR", "url": "https://omabrowser.org/oma/group/CDYYQSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8Q9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19432:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19432:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29019", "url": "https://www.rhea-db.org/rhea/29019", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69556", "url": "https://www.rhea-db.org/rhea/69556", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z8Q9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHPWRRPRLSAVMIPPSATTPIGDAALLPSVASQETWRSQIPGYSGSVTQHISHRANNFKRHPKRRKLIRPSPPPPPNTPCPIDLIGFGDLQPRRSFLELLFNGCILFGLEFSYAMETAYVTPVLLQMGLPDQLYGMVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAVGALFGLSLMLNGRDIGSALSDTVNNHKWGIVLTVCGVVLMDFSADSADNPSHAYMMDVCSPMDQDRGLNIHALLAGLGGGFGYVIGGIHWDKTSFGKAVGGQLRVIYVFTSIILTITTVLTLISIPERPLGSFSRKKKVMKSPSLPLPPSPPLFFEEGVNENFASRNSDHLYASFTSPVSPLSPLTPKYGSFVSRDNSLTGINEFASSFGTSNIDSVLIDCFTGGHSSYLALPASLPRQPVSVSFPRVPDGCYQQENGILEQGERSIIPGPDGEALRVGSLDAIKPRSSGILKRPQSLAIPDIVTGHCPESSRRRNVTFSQQVANILLDGVKYESELNGSGETSEQPLSMRLLCSTICHMPRALRNLCINHFLGWLSFEGMLLFYTDFMGEVVFEGNPKAPHNSDEYQKYNAGVTMGCWGMCIYAFSAAFYSAALEKLEERFSTRTLYFIAYLAFGLGTGLATLSRNIYIVLSLCTTYGILFATLCTLPYSLLCDYYQSCEFAGSHTEGTRRGMGVDISLLSCQYFLAQILVALAMGPLTTAVGSASGTMYFASLVSFLGCLFSSLCVIYEPTLSTEELPPTEEQSPLLPCVQD", "length": 771, "header": "tr|A0A8V0ZEM3-1|A0A8V0ZEM3_CHICK Isoform 1 of Proton-associated sugar transporter A OS=Gallus gallus OX=9031 GN=SLC45A1 PE=3 SV=1 CANONICAL=A0A8V0ZEM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3/entry#A0A8V0Z8Q9-1", "sequence": { "sequence": "MIPPSATTPIGDAALLPSVASQETWRSQIPGYSGSVTQHISHRANNFKRHPKRRKLIRPSPPPPPNTPCPIDLIGFGDLQPRRSFLELLFNGCILFGLEFSYAMETAYVTPVLLQMGLPDQLYGMVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAVGALFGLSLMLNGRDIGSALSDTVNNHKWGIVLTVCGVVLMDFSADSADNPSHAYMMDVCSPMDQDRGLNIHALLAGLGGGFGYVIGGIHWDKTSFGKAVGGQLRVIYVFTSIILTITTVLTLISIPERPLGSFSRKKKVMKSPSLPLPPSPPLFFEEGVNENFASRNSDHLYASFTSPVSPLSPLTPKYGSFVSRDNSLTGINEFASSFGTSNIDSVLIDCFTGGHSSYLALPASLPRQPVSVSFPRVPDGCYQQENGILEQGERSIIPGPDGEALRVGSLDAIKPRSSGILKRPQSLAIPDIVTGHCPESSRRRNVTFSQQVANILLDGVKYESELNGSGETSEQPLSMRLLCSTICHMPRALRNLCINHFLGWLSFEGMLLFYTDFMGEVVFEGNPKAPHNSDEYQKYNAGVTMGCWGMCIYAFSAAFYSAALEKLEERFSTRTLYFIAYLAFGLGTGLATLSRNIYIVLSLCTTYGILFATLCTLPYSLLCDYYQSCEFAGSHTEGTRRGMGVDISLLSCQYFLAQILVALAMGPLTTAVGSASGTMYFASLVSFLGCLFSSLCVIYEPTLSTEELPPTEEQSPLLPCVQD", "length": 758, "header": "tr|A0A8V0Z8Q9-1|A0A8V0ZEM3_CHICK Computationally mapped isoform of Proton-associated sugar transporter A OS=Gallus gallus OX=9031 GN=SLC45A1 PE=3 SV=1 CANONICAL=A0A8V0ZEM3-1" }, "locus": { "chromosome": "21", "start_pos": 211698, "end_pos": 204366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045224.1", "url": "https://www.ensembl.org/id/ENSGALT00010045224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027001.1", "url": "https://www.ensembl.org/id/ENSGALP00010027001.1" } ] } }, { "isoform_ac": "A0A8V0ZEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3/entry#A0A8V0ZEM3-1", "sequence": { "sequence": "MTHPWRRPRLSAVMIPPSATTPIGDAALLPSVASQETWRSQIPGYSGSVTQHISHRANNFKRHPKRRKLIRPSPPPPPNTPCPIDLIGFGDLQPRRSFLELLFNGCILFGLEFSYAMETAYVTPVLLQMGLPDQLYGMVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAVGALFGLSLMLNGRDIGSALSDTVNNHKWGIVLTVCGVVLMDFSADSADNPSHAYMMDVCSPMDQDRGLNIHALLAGLGGGFGYVIGGIHWDKTSFGKAVGGQLRVIYVFTSIILTITTVLTLISIPERPLGSFSRKKKVMKSPSLPLPPSPPLFFEEGVNENFASRNSDHLYASFTSPVSPLSPLTPKYGSFVSRDNSLTGINEFASSFGTSNIDSVLIDCFTGGHSSYLALPASLPRQPVSVSFPRVPDGCYQQENGILEQGERSIIPGPDGEALRVGSLDAIKPRSSGILKRPQSLAIPDIVTGHCPESSRRRNVTFSQQVANILLDGVKYESELNGSGETSEQPLSMRLLCSTICHMPRALRNLCINHFLGWLSFEGMLLFYTDFMGEVVFEGNPKAPHNSDEYQKYNAGVTMGCWGMCIYAFSAAFYSAALEKLEERFSTRTLYFIAYLAFGLGTGLATLSRNIYIVLSLCTTYGILFATLCTLPYSLLCDYYQSCEFAGSHTEGTRRGMGVDISLLSCQYFLAQILVALAMGPLTTAVGSASGTMYFASLVSFLGCLFSSLCVIYEPTLSTEELPPTEEQSPLLPCVQD", "length": 771, "header": "tr|A0A8V0ZEM3-1|A0A8V0ZEM3_CHICK Isoform 1 of Proton-associated sugar transporter A OS=Gallus gallus OX=9031 GN=SLC45A1 PE=3 SV=1 CANONICAL=A0A8V0ZEM3-1" }, "locus": { "chromosome": "21", "start_pos": 212273, "end_pos": 204366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045220.1", "url": "https://www.ensembl.org/id/ENSGALT00010045220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026999.1", "url": "https://www.ensembl.org/id/ENSGALP00010026999.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB13AA61-1", "protein_name": "Proton-associated sugar transporter A", "gene_name": "slc45a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSPGMGTPSDPLLSSPVGGKFGSAQDATWRPTLSKTSSFPTSTTRHLSHRANNFQRHPKRRKLIRPSPPPPPNTPCPLEQLDLSELPPRRTFPELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQFYSLVWFISPILGFLLQPILGAWSDRCTSRFGRRRPFIFALAIGALLGLTLVLNGRDIGSALADTTLDHKWGIVLTVCGVVLMDFSADSADNPSHAYMMDVCSPEDQDRGLNIHALLAGLGGGFGYIVGGINWDKTEFGRTMGGQLRVIYLFTSITLAAATAMTLTSIPERPLPQSQPQTRNTRNLKSPNLPLPPSPPPPPGAAADQDEEDEEEALYNSQFSNCRNPDLFGRSSSANARLYAGLTSPISPLSPLTPKYGSFISRDNSLTGINEFASSLGTSYIDRVLIECYTGQQTPQPMECEAVAVAPPLPPGDTPPPHGQSETLEVPQQIKVSQPNGELATDALQADEQKQAIEPDEQQNEAAAGSQRGSSSGILKRPQSLALMEDPLIAPSAGLDNGRRRTVTFSQQVANILLNGMRYDSDLSGNHEAADSQMSIKLLCTAIYRMPPCLRSLCTNHFLGWLSFEGMLLFYTDFMGEVVFGGDPKAHHDSEEYKRYNSGVSMGCWGMCIYAFSAAFYSAILEKLEERFSLRSLYFFAYLAFGLGTGLATLSTNLYVVLSLCVTYGVLFSSLCTLPYSLLCEYYQSPQFCGSSEDGTRRGMGVDISLLSCQYFLAQILVSVAMGPLTSLVGGAQGVMYFSSLMSFVGCLYSSLCVVYHLPPPEGEPPQSETQPLLAERTLRPWCE", "length": 815 }, "evidence": [ { "id": "A0A8V0ZEM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZEM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RII1-1", "protein_name": "Proton-associated sugar transporter A", "gene_name": "SLC45A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQQQRRAGGCRAGTQAEHRAGGSPASERDASWLEPQEHPPAPPTMIPPASSAPPGEALFPALAPQDFWRPPIAGYSGSVTQHISHRANNFKRHPKRRKCIRPSPPPPPNTPCPIELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDLGVALADTASDHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYIFTAVTLSITTVLTLVSIPERPLRPPGEKRTVMKSPSLPLPPSPPVLCEEGAGQPVPGQTASSLYASFSSPISPLSPLTPKYGSFISRDNSLTGLSEFASSFATSNIDSVLIDCFTGGPDGYLAIPGSVPRPGISVSFPRAPDGFYRQDRGLGDRRDAALATGPNGDVLQVGSLDTSKPRSAGILKRPQTLALPDAAGGGGSDTSRRRNVTFSQQVANILLNGVKYESELTGSSEPSGQPLSMRRLCFTIWNMPRALRHLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPPASEAYQKYSGGVAMGCWGMCIYAFSAAFYSAILEKLEEHLSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCVTYGILFSTLCTVPYSLLCDYYQSRQFAGSSADGTRRGMGVDISLLSCQYFLAQILVALVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVVYEIPPSDTAAEEHQPLLLNV", "length": 797 }, "evidence": [ { "id": "A0A8V0ZEM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZEM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BIV7-1", "protein_name": "Proton-associated sugar transporter A", "gene_name": "Slc45a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPPASSTPPGEAVIPSVAPQDFWRSPISSYSGSVTGHISHRANNFKRHPKRRKYIRPSPPPPPNTPCPIELVDFGDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATNHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYVFTAITLSVTTVLTLISIPERPLRPLGEKRTAMKSPSLPLPPSPPVLLEEGAGDALPSTTATSLYASFSSPISPPSPLTPKYGSFISRDSSLTGINEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSVPRQAISVSFPRAPDGFYCQERGLERREGPLTLGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRHLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIPSVDAADEERQPLLLNV", "length": 751 }, "evidence": [ { "id": "A0A8V0ZEM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZEM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4S3-1", "protein_name": "Proton-associated sugar transporter A", "gene_name": "Slc45a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPPAGSTPPGEALIPSVAPQDFWRSPISGYSGSVTRHISHRANNFKRHPKRRKYIRPSPPPPPNTPCPIELVDFEDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATNHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYIFTAITLSVTTVFTLVSIPERPLRPLGEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATSLYASFSSPISPPSPLTPKYGSFISRDSSLTGINEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSVPRQAISVSFPRAPDGFYCQERGLERREGPLTLGLDGDVLRVGSLDTSKPRASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRRLCSTIYNMPRPVRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHASEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLLFGLGTGLATLSRNLYVVLSLCTHYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFASLVSFLGCLYSSLCVTYEIPSADAADEERQPLLLNV", "length": 751 }, "evidence": [ { "id": "A0A8V0ZEM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZEM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y2W3-1", "protein_name": "Proton-associated sugar transporter A", "gene_name": "SLC45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQQVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVIYEIPPSDAADEEHRPLLLNV", "length": 748 }, "evidence": [ { "id": "A0A8V0ZEM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZEM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "D-glucose:proton symporter activity", "id": "GO:0005356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ], "pmid": "" }, { "name": "sucrose:proton symporter activity", "id": "GO:0008506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29019", "name": "", "equation": "D-galactose(in) + H(+)(in) = D-galactose(out) + H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29019", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29019" } ] }, { "id": "69556", "name": "", "equation": "D-glucose(out) + H(+)(out) = D-glucose(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69556", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69556" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 123 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 493, "end_pos": 495 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBG8-1", "uniprot_ac": "A0A8V0ZBG8", "uniprot_id": "A0A8V0ZBG8_CHICK", "mass": { "chemical_mass": 84296.0, "monoisotopic_mass": 84296.0 }, "refseq": { "ac": "XP_004943046", "name": "cyclin-T2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943046" }, "gene_names": [ { "name": "CCNT2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ] }, { "name": "CCNT2", "type": "synonym", "evidence": [ { "id": "XP_004943046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943046" } ] } ], "protein_names": [ { "name": "Cyclin T2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8/entry#names_and_taxonomy" } ] }, { "name": "cyclin-T2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943046" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943046" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8", "locus": { "chromosome": "7", "start_pos": 30100570, "end_pos": 30077279, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019587", "url": "https://www.ensembl.org/id/ENSGALG00010019587" } ] } } ], "crossref": [ { "id": "A0A8V0ZBG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20596", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20596", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20598", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20598", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424289", "url": "https://www.ncbi.nlm.nih.gov/gene/424289", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424289", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424289", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCSVKQY", "url": "https://omabrowser.org/oma/group/SCSVKQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Z4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2173796", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6796648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGGEEAGAALPPAGGAAGGGGGSVMAAAGSGAGTSTRGGGGSSAASRWFFSREQLENTPSRRCGVEADKELSYRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQPRKLEHVIKVVNACLHPHEPQLDTKCDAYLQQAQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPSVTLELLDELTHEFLQILEKTPSRLKRIRNWRANQAAKKPKGDGQVSENSLLGSSLVQNSILVDTVTGVAANTSFQKPSTSFPAPVPLTSGSISVPDSHAPENLAILATGMPSTSYNLASHQEWPQHQEQTRTEQIYSQKQEALPPSQYNMNFQQGTSVQLHAGVHHRPDKLAEHSTVKQEYSHKSGNKHHGQVAAPIIIPQKMSLDKYREKRKLETLELDVREHYVATPGEQTHKKHVQAQSASSTSVTSPIKMKIPIANAEKPEKHLTDKKEKSGSLKLRIPIPPTEKGASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHVSKEHKEKHKEHSLNRHHSIGHKHSHSHSGGSSSGGSKHNTDGLTPTVLRSPVGLGLSSDGNSSSSSSSRKKLYSNDASHNHHSKMSKSSKSSGSSSSSSSVKQYVSSHNSVFNLPLPPPPPVTYQVGYGHLSTLVKLDRKPVENGPDASHQYSTNSQHMDYKDTFDMLDSLLSAQGMNI", "length": 770, "header": "tr|A0A8V0ZBG8-1|A0A8V0ZBG8_CHICK Isoform 1 of Cyclin T2 OS=Gallus gallus OX=9031 GN=CCNT2 PE=1 SV=1 CANONICAL=A0A8V0ZBG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8/entry#A0A8V0Z9Z4-1", "sequence": { "sequence": "MEGGGEEAGAALPPAGGAAGGGGGSVMAAAGSGAGTSTRGGGGSSAASRWFFSREQLENTPSRRCGVEADKELSYRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQPRKLEHVIKVVNACLHPHEPQLDTKCDAYLQQAQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPSVTLELLDELTHEFLQILEKTPSRLKRIRNWRANQAAKKPKGDGQVSENSLLGSSLVQNSILVDTVTGVAANTSFQKPSTSFPAPVPLTSGSISVPDSHAPENLAILATGMPSTSYNLASHQEWPQHQEQTRTEQIYSQKQEALPPSQYNMNFQQGTSVQLHAGVHHRPDKLAEHSTVKQEYSHKSGNKHHGQVAAPIIIPQKMSLDKYREKRKLETLELDVREHYVATPGEQTHKKHVQAQSASSTSVTSPIKMKIPIANAEKPEKHLTDKKEKSGSLKLRIPIPPTEKGASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHVSKEHKEKHKEHSLNRHHSIGHKHSHSHSGGSSSGGSKHNTDGLTPTVLRSPVGLGLSSDGNSSSSSSSRKKLYSNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQETSGERS", "length": 704, "header": "tr|A0A8V0Z9Z4-1|A0A8V0ZBG8_CHICK Computationally mapped isoform of Cyclin T2 OS=Gallus gallus OX=9031 GN=CCNT2 PE=1 SV=1 CANONICAL=A0A8V0ZBG8-1" }, "locus": { "chromosome": "7", "start_pos": 30099303, "end_pos": 30077478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047257.1", "url": "https://www.ensembl.org/id/ENSGALT00010047257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028009.1", "url": "https://www.ensembl.org/id/ENSGALP00010028009.1" } ] } }, { "isoform_ac": "A0A8V0ZBG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8/entry#A0A8V0ZBG3-1", "sequence": { "sequence": "MAAAGSGAGTSTRGGGGSSAASRWFFSREQLENTPSRRCGVEADKELSYRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQPRKLEHVIKVVNACLHPHEPQLDTKCDAYLQQAQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRGHAKRLRRGDRTIIP", "length": 192, "header": "tr|A0A8V0ZBG3-1|A0A8V0ZBG8_CHICK Computationally mapped isoform of Cyclin T2 OS=Gallus gallus OX=9031 GN=CCNT2 PE=1 SV=1 CANONICAL=A0A8V0ZBG8-1" }, "locus": { "chromosome": "7", "start_pos": 30090743, "end_pos": 30077556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047239.1", "url": "https://www.ensembl.org/id/ENSGALT00010047239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028000.1", "url": "https://www.ensembl.org/id/ENSGALP00010028000.1" } ] } }, { "isoform_ac": "A0A8V0ZBG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8/entry#A0A8V0ZBG8-1", "sequence": { "sequence": "MEGGGEEAGAALPPAGGAAGGGGGSVMAAAGSGAGTSTRGGGGSSAASRWFFSREQLENTPSRRCGVEADKELSYRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQPRKLEHVIKVVNACLHPHEPQLDTKCDAYLQQAQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPSVTLELLDELTHEFLQILEKTPSRLKRIRNWRANQAAKKPKGDGQVSENSLLGSSLVQNSILVDTVTGVAANTSFQKPSTSFPAPVPLTSGSISVPDSHAPENLAILATGMPSTSYNLASHQEWPQHQEQTRTEQIYSQKQEALPPSQYNMNFQQGTSVQLHAGVHHRPDKLAEHSTVKQEYSHKSGNKHHGQVAAPIIIPQKMSLDKYREKRKLETLELDVREHYVATPGEQTHKKHVQAQSASSTSVTSPIKMKIPIANAEKPEKHLTDKKEKSGSLKLRIPIPPTEKGASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHVSKEHKEKHKEHSLNRHHSIGHKHSHSHSGGSSSGGSKHNTDGLTPTVLRSPVGLGLSSDGNSSSSSSSRKKLYSNDASHNHHSKMSKSSKSSGSSSSSSSVKQYVSSHNSVFNLPLPPPPPVTYQVGYGHLSTLVKLDRKPVENGPDASHQYSTNSQHMDYKDTFDMLDSLLSAQGMNI", "length": 770, "header": "tr|A0A8V0ZBG8-1|A0A8V0ZBG8_CHICK Isoform 1 of Cyclin T2 OS=Gallus gallus OX=9031 GN=CCNT2 PE=1 SV=1 CANONICAL=A0A8V0ZBG8-1" }, "locus": { "chromosome": "7", "start_pos": 30099403, "end_pos": 30077478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047252.1", "url": "https://www.ensembl.org/id/ENSGALT00010047252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028005.1", "url": "https://www.ensembl.org/id/ENSGALP00010028005.1" } ] } }, { "isoform_ac": "A0A8V0ZHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8/entry#A0A8V0ZHF4-1", "sequence": { "sequence": "MLYLKIISPTALFLAAKVEEQPRKLEHVIKVVNACLHPHEPQLDTKCDAYLQQAQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPSVTLELLDELTHEFLQILEKTPSRLKRIRNWRANQAAKKPKGDGQVSENSLLGSSLVQNSILVDTVTGVAANTSFQKPSTSFPAPVPLTSGSISVPDSHAPENLAILATGMPSTSYNLASHQEWPQHQEQTRTEQIYSQKQEALPPSQYNMNFQQGTSVQLHAGVHHRPDKLAEHSTVKQEYSHKSGNKHHGQVAAPIIIPQKMSLDKYREKRKLETLELDVREHYVATPGEQTHKKHVQAQSASSTSVTSPIKMKIPIANAEKPEKHLTDKKEKSGSLKLRIPIPPTEKGASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHVSKEHKEKHKEHSLNRHHSIGHKHSHSHSGGSSSGGSKHNTDGLTPTVLRSPVGLGLSSDGNSSSSSSSRKKLYSNDASHNHHSKMSKSSKSSGGLRTSQHPRETGQETSGERS", "length": 590, "header": "tr|A0A8V0ZHF4-1|A0A8V0ZHF4_CHICK Computationally mapped isoform of Cyclin T2 OS=Gallus gallus OX=9031 GN=CCNT2 PE=3 SV=1 CANONICAL=A0A8V0ZBG8-1" }, "locus": { "chromosome": "7", "start_pos": 30099303, "end_pos": 30083876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047246.1", "url": "https://www.ensembl.org/id/ENSGALT00010047246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028003.1", "url": "https://www.ensembl.org/id/ENSGALP00010028003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424289", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424289", "resource": "KEGG Pathway" }, { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-2173796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173796", "resource": "Reactome", "description": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QAB1-1", "protein_name": "Cyclin-T2a isoform 1", "gene_name": "ccnt2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAACRGSSSKWFFTREQLETTPSRRCGVEPDRELSYRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMYHSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAHACLNPQEPPLDTKSNAYLQQAQELVILETIVLQTLGFEITIEHPHTDVVKCSQLVRASKDLAQTSYFMATNSLHLTTFCLQHKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDNSVTLELLDELTHEFLQILEKTPSRLKRIRNWRATQAAKKPKSDNQGSDSSSLAGSSLTQDPSLMDTLPGVSTSTAFSKGSTSFPVCLSGNSSSSLSLDSIANMQGTSYTYTAPSDWPQDQLRSDPYSVKQLPSHSSMHPQRPDKSADLNPTKHEHKVSGGTKHQATTYPPHAAPTQKMSLDKYREKHAAELAVQKRKQEQQNVETEVYGATTQTDHRKHLPHLSHGQQGAGVTTASPLKIKLPGQDKIQDKCEKGSSLKLRLPVPSQSEKGGSSKEELKMKIKVSSERHSSSDEGAAKSKHSSPLVSKEKHRDHSAHRHHHKHGHSHTHTHSGNGRSSLEVPTTGSVADGPSSASSSSRKRVNPEASHNHHSKKNKSSKSGAGSSSHCSSVQQCVSSHNSVLNLPFPPPPVTYQVGYGHLSTLVKLDRKPVESHGPENACLANGQHTDCKDTFVMLDSLLSAQAMNS", "length": 693 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8W4F719-1", "protein_name": "Cyclin T2", "gene_name": "CCNT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SQLTINTAIVYMHRFYMHHSFTKFNRYTISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKKIRNWRATQTVKKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPGTSYGLSSHQEWPQHQESARTEQIYSQKQETSLSGSQYNINFQQGPSISMHSGLHHRPDKISDHSSIKQDYTHKAGSSKHHGPISATPGVIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKHGQSQAASSSSVTSPIKMKIPITNAEKPDKYMADKKEKSGSLKLRIPIPPTDKSISKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSNRHHPSSHKHSHSYSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKKLHINDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDVNHEYSTNSQHMDYKDTFDMLDSLLSAQGMNM", "length": 680 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZGL6-1", "protein_name": "Cyclin T2", "gene_name": "Ccnt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGRGASSRWFFTREQLENTPSRRCGVEADEELSHRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRIRNWRAMAKKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPANPSFQKPSTSTFPAPLPLTSGSTSVQDGRASDTGSVLAGMPSSSYTVSSHQEWPHHPDSARTDPVYTQKQEATLSGSQYLSFQQGPSMALHSGLHHRPDKVADHSSAKQEYTHKGGSSKHHGPIPATPGVVPQKMSLDKYREKRKLETLDLDSRDHYMAAHAEQQHKHGPAQAVAGTSVTSPIKMKLPLTNSDKPEKHLAEKRERSGSLKLRIPIPPPDKGPSKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPANRHHSSHKHLHMHSSGGSKHADGMPPTVLRSPVGLGPEGISSGPSARKKLHINDASHNHHSKMSKSSKSSGSSSSSSSVKQYLSSHSSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVEPHGPEANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM", "length": 722 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B6Z5-1", "protein_name": "Cyclin-T1", "gene_name": "CCNT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSGAEHCGPVRESEDGGRKEKAKGLGEPIGRSPRTRTRGDWGEKGQCLVYGERSGAGSRGLGGESASPEGRGVGEGAGGGGSVMASGRGASSRWFFTREQLENTPSRRCGVEADKELSYRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFSRYMISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDTYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKKIRYWRANQAAGKPKVDGQVSETPLLGSSLVQNSMLVDSVTGVPTKPSFQKPSTSAFPAPVPLNSGNISVQDSHASDNLSMLATGMPSTSYGLSSHQEWPQHQESARTEQIYSQKQEISGSQYNINFKQGPSVSLHSGLHHRPDKISDHSSVKQDYTHKAGSSKHHGPISATPGVIPQKMSLDKYREKRKLESLDLDARDHYIAAQVEQQHKHVQSQAASSSSVTSPIKMKIPITNAEKPEKYMAEKKEKSGSLKLRIPIPPTDKSVSKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSNRHHPSSHKHSHSYSGSSSGGSKHSADGIAPTVLRSPVGLSSDGISSSSSSSRKKLHINDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDVNHEYSTNSQHMDYKDTFDMLDSLLSAQGMNM", "length": 815 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GZQ2-1", "protein_name": "Cyclin-T2 isoform X1", "gene_name": "Ccnt2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASGRGASSRWFFTREQLENTPSRRCGVEADEELSHRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRIRNWRAMAKKPKVDGQVSETPLLGSSLVQNSLLVDSVTGVPANPSFQKPSTSTFPAPIPLNPGNTSVQDSRASDTLSVLAAGMPSTSYSLSSHQEWPQHPDSARTDPVYTQKQEATLSGSQYISFQQGPSMTLHSGLHHRPDKIADHSSAKQEYAHKSGSSKHHGPIPAAPGVVPQKMSLDKYREKRKLETLDLDTRDHYIAAHVEQQHKHGPAQAVAGSSVTSPIKMKLPVTNSDKSEKHMAEKKEKSGSLKLRIPIPPPDKGPSKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHINRDHKEKHKEHPANRYHSSHKHLHMLSGGGSKHAADGMPPTVLRSPVGLGPDSISSSSSARKKLHINDASHNHHSKMSKSSKSSGSSSSSSSVKQYLSSHSSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVEPHGPEANHEYSTSSQHLDYKDTFDMLDSLLSAQGMNM", "length": 724 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60583-1", "protein_name": "Cyclin-T2", "gene_name": "CCNT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM", "length": 730 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQK0-1", "protein_name": "Cyclin-T2", "gene_name": "Ccnt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGRGASSRWFFTREQLENTPSRRCGVEADEELSHRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLKRIRNWRAMAKKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPANPSFQKPSTSTFPAPIPLNSGSTSVQDSRASDNLSVLAAGMPSTSYSLSSHQEWPQHPDSARTDPVYTQKQEATLSGSQYISFQQGPSMALHSGLHHRPDKVADHSSAKQEYTHKAGSSKHHGPIPATPGMLPQKMSLDKYREKRKLETLDVDTRDHYLAAHAEQQHKHGPAQAVTGTSVTSPIKMKLPLTNSDRPEKHVAEKKERSGSLKLRIPIPPPDKGPSKEELKMKIKVASSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPANRHHSSHKYLHMHSGGSKHTADGMPPTVLRSPVGLGPEGVSSASSARKKLHSSEASHNHHSKMSKSSKSAGSSSSSSSVKQYLSSHSSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVEPHGPEANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM", "length": 723 }, "evidence": [ { "id": "A0A8V0ZBG8", "url": "https://omabrowser.org/oma/group/A0A8V0ZBG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "early viral transcription", "id": "GO:0019085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "late viral transcription", "id": "GO:0019086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019086", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "RNA polymerase binding", "id": "GO:0070063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "7SK snRNA binding", "id": "GO:0097322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097322", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBG8" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 180, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 337, "end_pos": 339 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBR3-1", "uniprot_ac": "A0A8V0ZBR3", "uniprot_id": "A0A8V0ZBR3_CHICK", "mass": { "chemical_mass": 116779.0, "monoisotopic_mass": 116779.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ITPR interacting domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA92", "url": "https://www.orthodb.org/?gene=A0A8V0ZA92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBR3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17469:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17469:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZA92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQYPYWHRSLQEFSESPVMSRCNSLRSSHSHTGGPQSITEWLSLCEKDPVEILLDLGFGTEEPDVCTKIPPRFLSGSSVAKGIDIRVFLEAQKQRMDIELPNLYGRFRQLEVLDHITSALSSLLTDVNTQQTKAQETGGNVTSHLNAVKSRSEVTQAKRRRIGQLLRRASQQTALRKLGSLTPEEVSMPGTEEQPHLCVDIAERGPIHTGFSAHVTLGCLTQEQTRRAKGSSAYPISPCPPSLPGKTCALSHLVTKQLHLSSPCEVPAKDRPRKEPHLFLAQMLKKLAGLNCRPPDSFEMEEIQSFEDEILCGNTPDTTSKMMVTRTSSCQSDSSGFMEELPEPFVLQNASLSREMNIFSDLYNQQTALSHATEFPLLNQDFQQNQGDCVGEVLITACESIVAVSRPTKACKDQGEEISLLLTAENGEHQACNAELQSFVQERLCGMKEYKTERQHLEKEDCIEENTPSFKGDTQDEGDPVSLKFHCQFHFSTGHKNMNAAFTELSDTNPVFITESKLRDDDESERGLMEKDSEVTCHRNVHRDCTECGEERRWGVEVVVKNGALLAVNEETNRQNFRKMGADAKKIRCFSRRGLPETLCKGCANPSCSSQVSHRPPLCQTEGPGLSSPNDQQIGGTREMLGTNKPELGDPVQNCEMTRIPMRSVTVQMPSGLEFTSMVKCTTQNVPCTESLARDDHVDLSKVVAHCSEGASPIWSDPGASEDSVKQITDTPSQTAENRKTRQLPVLCPPHSHLTKSASLDTMLSGKYRPHRCSETSGMMGAQGNPCCHHCCCHGCCCLWTCPVAVSPHSPMCCCSNQAANKLQLLRTLKFLQENTMRNLPLCSHEIELMKISCQHFHEKLDEIEQHLTEQQALFANYMPEEGREESRNLQHLRQAVRQEMAELELCLNDKAYQVGEGILMQLDQLLVEQSHLFSELGLSDWKGERNAQNKQALPDAAGARSGCSERVPQRAASKNTTAAGSLSALQPGAPLTPLPTRTVPEPNSSMLDLQEPSISKEEIKGPPQAKSDFKAFIHNVRSCSSLTLKVVSGRDH", "length": 1053, "header": "tr|A0A8V0ZBR3-1|A0A8V0ZBR3_CHICK Isoform 1 of ITPR interacting domain containing 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3/entry#A0A8V0ZA92-1", "sequence": { "sequence": "MSRCNSLRSSHSHTGGPQSITEWLSLCEKDPVEILLDLGFGTEEPDVCTKIPPRFLSGSSVAKGIDIRVFLEAQKQRMDIELPNLYGRFRQLEVLDHITSALSSLLTDVNTQQTKAQETGGNVTSHLNAVKSRSEVTQAKRRRIGQLLRRASQQTALRKLGSLTPEEVSMPGTEEQPHLCVDIAERGPIHTGFSAHVTLGCLTQEQTRRAKGSSAYPISPCPPSLPGKTCALSHLVTKQLHLSSPCEVPAKDRPRKEPHLFLAQMLKKLAGLNCRPPDSFEMEEIQSFEDEILCGNTPDTTSKMMVTRTSSCQSDSSGFMEELPEPFVLQNASLSREMNIFSDLYNQQTALSHATEFPLLNQDFQQNQGDCVGEVLITACESIVAVSRPTKACKDQGEEISLLLTAENGEHQACNAELQSFVQERLCGMKEYKTERQHLEKEDCIEENTPSFKGDTQDEGDPVSLKFHCQFHFSTGHKNMNAAFTELSDTNPVFITESKLRDDDESERGLMEKDSEVTCHRNVHRDCTECGEERRWGVEVVVKNGALLAVNEETNRQNFRKMGADAKKIRCFSRRGLPETLCKGCANPSCSSQVSHRPPLCQTEGPGLSSPNDQQIGGTREMLGTNKPELGDPVQNCEMTRIPMRSVTVQMPSGLEFTSMVKCTTQNVPCTESLARDDHVDLSKVVAHCSEGASPIWSDPGASEDSVKQITDTPSQTAENRKTRQLPVLCPPHSHLTKSASLDTMLSGKYRPHRCSETSGMMGAQGNPCCHHCCCHGCCCLWTCPVAVSPHSPMCCCSNQAANKLQLLRTLKFLQENTMRNLPLCSHEIELMKISCQHFHEKLDEIEQHLTEQQALFANYMPEEGREESRNLQHLRQAVRQEMAELELCLNDKAYQVGEGILMQLDQLLVEQSHLFSELGLSDWKGERNAQNKQALPDAAGARSGCSERVPQRAASKNTTAAGSLSALQPGAPLTPLPTRTVPEPNSSMLDLQEPSISKEEIKGPPQAKSDFKAFIHNLKKSFQNPLGNDSAEGKD", "length": 1036, "header": "tr|A0A8V0ZA92-1|A0A8V0ZBR3_CHICK Computationally mapped isoform of ITPR interacting domain containing 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBR3-1" }, "locus": { "chromosome": "2", "start_pos": 48480855, "end_pos": 48448890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047457.1", "url": "https://www.ensembl.org/id/ENSGALT00010047457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028110.1", "url": "https://www.ensembl.org/id/ENSGALP00010028110.1" } ] } }, { "isoform_ac": "A0A8V0ZBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3/entry#A0A8V0ZBR3-1", "sequence": { "sequence": "MQYPYWHRSLQEFSESPVMSRCNSLRSSHSHTGGPQSITEWLSLCEKDPVEILLDLGFGTEEPDVCTKIPPRFLSGSSVAKGIDIRVFLEAQKQRMDIELPNLYGRFRQLEVLDHITSALSSLLTDVNTQQTKAQETGGNVTSHLNAVKSRSEVTQAKRRRIGQLLRRASQQTALRKLGSLTPEEVSMPGTEEQPHLCVDIAERGPIHTGFSAHVTLGCLTQEQTRRAKGSSAYPISPCPPSLPGKTCALSHLVTKQLHLSSPCEVPAKDRPRKEPHLFLAQMLKKLAGLNCRPPDSFEMEEIQSFEDEILCGNTPDTTSKMMVTRTSSCQSDSSGFMEELPEPFVLQNASLSREMNIFSDLYNQQTALSHATEFPLLNQDFQQNQGDCVGEVLITACESIVAVSRPTKACKDQGEEISLLLTAENGEHQACNAELQSFVQERLCGMKEYKTERQHLEKEDCIEENTPSFKGDTQDEGDPVSLKFHCQFHFSTGHKNMNAAFTELSDTNPVFITESKLRDDDESERGLMEKDSEVTCHRNVHRDCTECGEERRWGVEVVVKNGALLAVNEETNRQNFRKMGADAKKIRCFSRRGLPETLCKGCANPSCSSQVSHRPPLCQTEGPGLSSPNDQQIGGTREMLGTNKPELGDPVQNCEMTRIPMRSVTVQMPSGLEFTSMVKCTTQNVPCTESLARDDHVDLSKVVAHCSEGASPIWSDPGASEDSVKQITDTPSQTAENRKTRQLPVLCPPHSHLTKSASLDTMLSGKYRPHRCSETSGMMGAQGNPCCHHCCCHGCCCLWTCPVAVSPHSPMCCCSNQAANKLQLLRTLKFLQENTMRNLPLCSHEIELMKISCQHFHEKLDEIEQHLTEQQALFANYMPEEGREESRNLQHLRQAVRQEMAELELCLNDKAYQVGEGILMQLDQLLVEQSHLFSELGLSDWKGERNAQNKQALPDAAGARSGCSERVPQRAASKNTTAAGSLSALQPGAPLTPLPTRTVPEPNSSMLDLQEPSISKEEIKGPPQAKSDFKAFIHNVRSCSSLTLKVVSGRDH", "length": 1053, "header": "tr|A0A8V0ZBR3-1|A0A8V0ZBR3_CHICK Isoform 1 of ITPR interacting domain containing 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBR3-1" }, "locus": { "chromosome": "2", "start_pos": 48495559, "end_pos": 48449802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047461.1", "url": "https://www.ensembl.org/id/ENSGALT00010047461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028111.1", "url": "https://www.ensembl.org/id/ENSGALP00010028111.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 976, "end_pos": 978, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR3" }, { "id": "SM01257", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01257" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ITPR-interacting", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 173, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1004, "end_pos": 1006 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 976, "end_pos": 978 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBL6-1", "uniprot_ac": "A0A8V0ZBL6", "uniprot_id": "A0A8V0ZBL6_CHICK", "mass": { "chemical_mass": 147175.0, "monoisotopic_mass": 147175.0 }, "refseq": {}, "gene_names": [ { "name": "CDAN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6" } ] } ], "protein_names": [ { "name": "Codanin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDAN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6", "locus": {} } ], "crossref": [ { "id": "IPR028171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI90", "url": "https://www.orthodb.org/?gene=A0A8V0ZI90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZAU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVLELLLSEEVAVGAVVRWLRRAPGQRPPEENHIHDKLVSLSLLQKDFVPFLLNFLREQTSQILTNGPSTPAKTPNSKAHRSQRTGPERRAGHATSSRVQLFSQRTPVTSCTTDTSFSPAAASSGSSSFSGSNLSSPCSDFPSVVSSSSPSFGYSPVLTHSEKRSAQKANLGSFLTAAPEALPARRGRRKGSSSVSASGRQVARDLGRSLAEEEDGKNESASWSGGRRKRNEVPLVTARSPPSQLNLNNLEEFPPMGTASGWTNKSKPSRRINPTPVSAERPLSKPKMCFTSTPVSQSPAARFLSGSSPEAFTTVQEGNSTSVISSSLQEEREMLKKERCKLLHQASSPAGISPDPGTPTKPTYTRSANLPAESHLVTCADPAKVSCKKQLECLAQLYSSCIAENLVPNIFLELFFVLQLLTSKGTSASEEEESDLEVSEGSEDASGRQHFRSVHNCVYFAVQVLDYQYEIISHLEKGTLKFLAENERIASFSPTLHERLKQAYESSTAKVSLLLPCSVQSVSFQPETDNRSNFPTDRAFHIFKKQRDIFYELLREWEDNHEKPGWDFERVLGSKIRAMMAHLSATCNHSHFARLFQKQLTQMCKDPIGGGASWGDTPDQDVLNMLGPDNLSRLKRLQERFVVPQSIRGPCPPPSFPGCQQFFRDFILSAGSYQFNQHLVDSLCLKILELDGLTLVEHEHSDGEADMDEQDEKKRFTVVLLSLRLLAKFLGFLVFLPYRTVEQPTRDLQDTAVALRNQTLPVLDILKLLRRSIRNQRSVLTIPWIVEFLSLVDHIAPFLDYYRKVFCLLLQIYRLMVLSEDKEMSFLNKLLILAVLGWLFQVPSVPEELFFATDVRQEGLVMDTVTSAQALDSVPLVDQQLLYTCCPYLGELRKLLASFVAGSGVKNGGFIRKITPTAAESLAPKTSITQQKLQVELEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVAELVQRAEVMLQDKVKEEDANHDKLLEEVCAHLYDEGAQALIKGREFCKKKGPEAVRVLLPEETSAAVLSSAEDIAVELATEKACGWLSANIAALIKREVKATLNRMLKVPGLPLPHEDARELRKDCSPGCLHRAPFPSQIINEIKDVLCVAVGPRDEGEVIDPGWLECLLGRLSQTLRCRKFMCPTSEQQLAKCTVELASLLVSGRVPLSLGIKPPEKSSERLRVKNNPTYDLLKLLLSVWKEDFGTPVPVQLMFSRKNIGYLAEVKQQEWDLFHFILRGLVECDLMQTSEIESCLRSLEELPWPSDFLKALESVSSLFLSEHLIEEPRSNPCDLTRHSLGTVTAQS", "length": 1323, "header": "tr|A0A8V0ZBL6-1|A0A8V0ZBL6_CHICK Isoform 1 of Codanin 1 OS=Gallus gallus OX=9031 GN=CDAN1 PE=4 SV=1 CANONICAL=A0A8V0ZBL6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6/entry#A0A8V0ZAU4-1", "sequence": { "sequence": "MLAFYFCNFKNGAYKGGQKGAGLAPPGREVRSHVLLRCTVTGRRLHAALRVKARRRRPALTHLPHGGAGQLQRVDAAHDGHGLGVQQGTVGAGVQENHIHDKLVSLSLLQKDFVPFLLNFLREQTSQILTNGPSTPAKTPNSKAHRSQRTGPERRAGHATSSRVQLFSQRTPVTSCTTDTSFSPAAASSGSSSFSGSNLSSPCSDFPSVVSSSSPSFGYSPVLTHSEKRSAQKANLGSFLTAAPEALPARRGRRKGSSSVSASGRQVARDLGRSLAEEEDGKNESASWSGGRRKRNEVPLVTARSPPSQLNLNNLEEFPPMGTASGWTNKSKPSRRINPTPVSAERPLSKPKMCFTSTPVSQSPAARFLSGSSPEAFTTVQEGNSTSVISSSLQEEREMLKKERCKLLHQASSPAGISPDPGTPTKPTYTRSANLPAESHLVTCADPAKVSCKKQLECLAQLYSSCIAENLVPNIFLELFFVLQLLTSKGTSASEEEESDLEVSEGSEDASGRQHFRSVHNCVYFAVQVLDYQYEIISHLEKGTLKFLAENERIASFSPTLHERLKQAYESSTAKVSLLLPCSVQSVSFQPETDNRSNFPTDRAFHIFKKQRDIFYELLREWEDNHEKPGWDFERVLGSKIRAMMAHLSATCNHSHFARLFQKQLTQMCKDPIGGGASWGDTPDQDVLNMLGPDNLSRLKRLQERFVVPQSIRGPCPPPSFPGCQQFFRDFILSAGSYQFNQHLVDSLCLKILELDGLTLVEHEHSDGEADMDEQDEKKRFTVVLLSLRLLAKFLGFLVFLPYRTVEQPTRDLQDTAVALRNQTLPVLDILKLLRRSIRNQRSVLTIPWIVEFLSLVDHIAPFLDYYRKVFCLLLQIYRLMVLSEDKEMSFLNKLLILAVLGWLFQVPSVPEELFFATDVRQEGLVMDTVTSAQALDSVPLVDQQLLYTCCPYLGELRKLLASFVAGSGVKNGGFIRKITPTAAESLAPKTSITQQKLQVELEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVAELVQRAEVMLQDKVKEEDANHDKLLEEVCAHLYDEGAQALIKGREFCKKKGPEAVRVLLPEETSAAVLSSAEDIAVELATEKACGWLSANIAALIKREVKATLNRMLKVPGLPLPHEDARELRKDCSPGCLHRAPFPSQIINEIKDVLCVAVGPRDEGEVIDPGWLECLLGRLSQTLRCRKFMCPTSEQQLAKCTVELASLLVSGRVPLSLGIKPPEKSSERLRVKNNPTYDLLKLLLSVWKEDFGTPVPVQLMFSRKNIGYLAEVKQQEWDLFHFILRGLVECDLMQTSEIESCLRSLEELPWPSDFLKALESVSSLFLSEHLIEEPRSNPCDLTRHSLGTVTAQS", "length": 1386, "header": "tr|A0A8V0ZAU4-1|A0A8V0ZBL6_CHICK Computationally mapped isoform of Codanin 1 OS=Gallus gallus OX=9031 GN=CDAN1 PE=4 SV=1 CANONICAL=A0A8V0ZBL6-1" }, "locus": { "chromosome": "5", "start_pos": 25393273, "end_pos": 25364629, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047959.1", "url": "https://www.ensembl.org/id/ENSGALT00010047959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028316.1", "url": "https://www.ensembl.org/id/ENSGALP00010028316.1" } ] } }, { "isoform_ac": "A0A8V0ZBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6/entry#A0A8V0ZBL6-1", "sequence": { "sequence": "MAAVLELLLSEEVAVGAVVRWLRRAPGQRPPEENHIHDKLVSLSLLQKDFVPFLLNFLREQTSQILTNGPSTPAKTPNSKAHRSQRTGPERRAGHATSSRVQLFSQRTPVTSCTTDTSFSPAAASSGSSSFSGSNLSSPCSDFPSVVSSSSPSFGYSPVLTHSEKRSAQKANLGSFLTAAPEALPARRGRRKGSSSVSASGRQVARDLGRSLAEEEDGKNESASWSGGRRKRNEVPLVTARSPPSQLNLNNLEEFPPMGTASGWTNKSKPSRRINPTPVSAERPLSKPKMCFTSTPVSQSPAARFLSGSSPEAFTTVQEGNSTSVISSSLQEEREMLKKERCKLLHQASSPAGISPDPGTPTKPTYTRSANLPAESHLVTCADPAKVSCKKQLECLAQLYSSCIAENLVPNIFLELFFVLQLLTSKGTSASEEEESDLEVSEGSEDASGRQHFRSVHNCVYFAVQVLDYQYEIISHLEKGTLKFLAENERIASFSPTLHERLKQAYESSTAKVSLLLPCSVQSVSFQPETDNRSNFPTDRAFHIFKKQRDIFYELLREWEDNHEKPGWDFERVLGSKIRAMMAHLSATCNHSHFARLFQKQLTQMCKDPIGGGASWGDTPDQDVLNMLGPDNLSRLKRLQERFVVPQSIRGPCPPPSFPGCQQFFRDFILSAGSYQFNQHLVDSLCLKILELDGLTLVEHEHSDGEADMDEQDEKKRFTVVLLSLRLLAKFLGFLVFLPYRTVEQPTRDLQDTAVALRNQTLPVLDILKLLRRSIRNQRSVLTIPWIVEFLSLVDHIAPFLDYYRKVFCLLLQIYRLMVLSEDKEMSFLNKLLILAVLGWLFQVPSVPEELFFATDVRQEGLVMDTVTSAQALDSVPLVDQQLLYTCCPYLGELRKLLASFVAGSGVKNGGFIRKITPTAAESLAPKTSITQQKLQVELEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVAELVQRAEVMLQDKVKEEDANHDKLLEEVCAHLYDEGAQALIKGREFCKKKGPEAVRVLLPEETSAAVLSSAEDIAVELATEKACGWLSANIAALIKREVKATLNRMLKVPGLPLPHEDARELRKDCSPGCLHRAPFPSQIINEIKDVLCVAVGPRDEGEVIDPGWLECLLGRLSQTLRCRKFMCPTSEQQLAKCTVELASLLVSGRVPLSLGIKPPEKSSERLRVKNNPTYDLLKLLLSVWKEDFGTPVPVQLMFSRKNIGYLAEVKQQEWDLFHFILRGLVECDLMQTSEIESCLRSLEELPWPSDFLKALESVSSLFLSEHLIEEPRSNPCDLTRHSLGTVTAQS", "length": 1323, "header": "tr|A0A8V0ZBL6-1|A0A8V0ZBL6_CHICK Isoform 1 of Codanin 1 OS=Gallus gallus OX=9031 GN=CDAN1 PE=4 SV=1 CANONICAL=A0A8V0ZBL6-1" }, "locus": { "chromosome": "5", "start_pos": 25392276, "end_pos": 25364629, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047950.1", "url": "https://www.ensembl.org/id/ENSGALT00010047950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028313.1", "url": "https://www.ensembl.org/id/ENSGALP00010028313.1" } ] } }, { "isoform_ac": "A0A8V0ZI90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6/entry#A0A8V0ZI90-1", "sequence": { "sequence": "MTVWRLAFRLTTCAKENHIHDKLVSLSLLQKDFVPFLLNFLREQTSQILTNGPSTPAKTPNSKAHRSQRTGPERRAGHATSSRVQLFSQRTPVTSCTTDTSFSPAAASSGSSSFSGSNLSSPCSDFPSVVSSSSPSFGYSPVLTHSEKRSAQKANLGSFLTAAPEALPARRGRRKGSSSVSASGRQVARDLGRSLAEEEDGKNESASWSGGRRKRNEVPLVTARSPPSQLNLNNLEEFPPMGTASGWTNKSKPSRRINPTPVSAERPLSKPKMCFTSTPVSQSPAARFLSGSSPEAFTTVQEGNSTSVISSSLQEEREMLKKERCKLLHQASSPAGISPDPGTPTKPTYTRSANLPAESHLVTCADPAKVSCKKQLECLAQLYSSCIAENLVPNIFLELFFVLQLLTSKGTSASEEEESDLEVSEGSEDASGRQHFRSVHNCVYFAVQVLDYQYEIISHLEKGTLKFLAENERIASFSPTLHERLKQAYESSTAKVSLLLPCSVQSVSFQPETDNRSNFPTDRAFHIFKKQRDIFYELLREWEDNHEKPGWDFERVLGSKIRAMMAHLSATCNHSHFARLFQKQLTQMCKDPIGGGASWGDTPDQDVLNMLGPDNLSRLKRLQERFVVPQSIRGPCPPPSFPGCQQFFRDFILSAGSYQFNQHLVDSLCLKILELDGLTLVEHEHSDGEADMDEQDEKKRFTVVLLSLRLLAKFLGFLVFLPYRTVEQPTRDLQDTAVALRNQTLPVLDILKLLRRSIRNQRSVLTIPWIVEFLSLVDHIAPFLDYYRKVFCLLLQIYRLMVLSEDKEMSFLNKLLILAVLGWLFQVPSVPEELFFATDVRQEGLVMDTVTSAQALDSVPLVDQQLLYTCCPYLGELRKLLASFVAGSGVKNGGFIRKITPTAAESLAPKTSITQQKLQVELEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVAELVQRAEVMLQDKVKEEDANHDKLLEEVCAHLYDEGAQALIKGREFCKKKGPEAVRVLLPEETSAAVLSSAEDIAVELATEKACGWLSANIAALIKREVKATLNRMLKVPGLPLPHEDARELRKDCSPGCLHRAPFPSQIINEIKDVLCVAVGPRDEGEVIDPGWLECLLGRLSQTLRCRKFMCPTSEQQLAKCTVELASLLVSGRVPLSLGIKPPEKSSERLRVKNNPTYDLLKLLLSVWKEDFGTPVPVQLMFSRKNIGYLAEVKQQEWDLFHFILRGLVECDLMQTSEIESCLRSLEELPWPSDFLKALESVSSLFLSEHLIEEPRSNPCDLTRHSLGTVTAQS", "length": 1306, "header": "tr|A0A8V0ZI90-1|A0A8V0ZI90_CHICK Computationally mapped isoform of Codanin 1 OS=Gallus gallus OX=9031 GN=CDAN1 PE=4 SV=1 CANONICAL=A0A8V0ZBL6-1" }, "locus": { "chromosome": "5", "start_pos": 25390172, "end_pos": 25364629, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047938.1", "url": "https://www.ensembl.org/id/ENSGALT00010047938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028310.1", "url": "https://www.ensembl.org/id/ENSGALP00010028310.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBL6" }, { "id": "PF15296", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Codanin-1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 874, "end_pos": 987, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277, 919 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 759, "end_pos": 761 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCB5-1", "uniprot_ac": "A0A8V0ZCB5", "uniprot_id": "A0A8V0ZCB5_CHICK", "mass": { "chemical_mass": 35091.0, "monoisotopic_mass": 35091.0 }, "refseq": { "ac": "XP_040535807", "name": "peroxisomal membrane protein 11A isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535807" }, "gene_names": [ { "name": "PEX11A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ] }, { "name": "PEX11A", "type": "synonym", "evidence": [ { "id": "XP_040535807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535807" } ] } ], "protein_names": [ { "name": "Peroxisomal biosis factor 11 alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal membrane protein 11A isoform X4", "type": "synonym", "evidence": [ { "id": "XP_040535807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535807" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052582.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040535807.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040535807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535807" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEX11A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5", "locus": { "chromosome": "10", "start_pos": 12833661, "end_pos": 12828091, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019867", "url": "https://www.ensembl.org/id/ENSGALG00010019867" } ] } } ], "crossref": [ { "id": "A0A8V0ZCB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "415486", "url": "https://www.ncbi.nlm.nih.gov/gene/415486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415486", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415486", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKRTMQL", "url": "https://omabrowser.org/oma/group/AKRTMQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZCB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIB1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12652:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12652:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040535807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535807", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGPLSPRGVPGRTLLAVTPPAPAPLCTGCHGNGALRRRPAGNALVSGGFRRETGRGGAAAHLPGCPAATAMQGFVDFTNRSQGRERIFRATQYTCMLLSYVIERKADNEKLVLKLKQLESSMSSGRKMFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 317, "header": "tr|A0A8V0ZCB5-1|A0A8V0ZCB5_CHICK Isoform 1 of Peroxisomal biosis factor 11 alpha OS=Gallus gallus OX=9031 GN=PEX11A PE=1 SV=1 CANONICAL=A0A8V0ZCB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5/entry#A0A8V0ZAV3-1", "sequence": { "sequence": "AEGSAVRRGGAERPLTSRGAQLPPPCRASWISPTAARGGRESSVFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 231, "header": "tr|A0A8V0ZAV3-1|A0A8V0ZCB5_CHICK Computationally mapped isoform of Peroxisomal biosis factor 11 alpha OS=Gallus gallus OX=9031 GN=PEX11A PE=1 SV=1 CANONICAL=A0A8V0ZCB5-1" }, "locus": { "chromosome": "10", "start_pos": 12831047, "end_pos": 12829107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047987.1", "url": "https://www.ensembl.org/id/ENSGALT00010047987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028327.1", "url": "https://www.ensembl.org/id/ENSGALP00010028327.1" } ] } }, { "isoform_ac": "A0A8V0ZAW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5/entry#A0A8V0ZAW3-1", "sequence": { "sequence": "MAEESPGDAARRAQTSFCLSRCKTQHRCGHQRRCRTRSRTVSAFMRATQYTCMLLSYVIERKADNEKLVLKLKQLESSMSSGRKMFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 272, "header": "tr|A0A8V0ZAW3-1|A0A8V0ZCB5_CHICK Computationally mapped isoform of Peroxisomal biosis factor 11 alpha OS=Gallus gallus OX=9031 GN=PEX11A PE=1 SV=1 CANONICAL=A0A8V0ZCB5-1" }, "locus": { "chromosome": "10", "start_pos": 12831047, "end_pos": 12828452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048002.1", "url": "https://www.ensembl.org/id/ENSGALT00010048002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028337.1", "url": "https://www.ensembl.org/id/ENSGALP00010028337.1" } ] } }, { "isoform_ac": "A0A8V0ZCB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5/entry#A0A8V0ZCB5-1", "sequence": { "sequence": "MPRGPLSPRGVPGRTLLAVTPPAPAPLCTGCHGNGALRRRPAGNALVSGGFRRETGRGGAAAHLPGCPAATAMQGFVDFTNRSQGRERIFRATQYTCMLLSYVIERKADNEKLVLKLKQLESSMSSGRKMFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 317, "header": "tr|A0A8V0ZCB5-1|A0A8V0ZCB5_CHICK Isoform 1 of Peroxisomal biosis factor 11 alpha OS=Gallus gallus OX=9031 GN=PEX11A PE=1 SV=1 CANONICAL=A0A8V0ZCB5-1" }, "locus": { "chromosome": "10", "start_pos": 12831047, "end_pos": 12828965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047988.1", "url": "https://www.ensembl.org/id/ENSGALT00010047988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028328.1", "url": "https://www.ensembl.org/id/ENSGALP00010028328.1" } ] } }, { "isoform_ac": "A0A8V0ZIB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5/entry#A0A8V0ZIB1-1", "sequence": { "sequence": "MRATQYTCMLLSYVIERKADNEKLVLKLKQLESSMSSGRKMFRLGNVVHALVAARKTTELPEVLPRICLTASNLTRALYFFCDTVLWLKSVGLQSDIKKAKWQNWATKCYYFSLLMNLARDWYEVSWRLEQAVQEEKMKENCFGDEQPQQRNSSKCNGLHGFLFLLFQILRSHPPLLLDVVKNLCDLSGPLDTLGIYKTNPGVIGFCGLLSSLVGILTLASPHLKLKE", "length": 228, "header": "tr|A0A8V0ZIB1-1|A0A8V0ZIB1_CHICK Computationally mapped isoform of Peroxisomal biosis factor 11 alpha OS=Gallus gallus OX=9031 GN=PEX11A PE=1 SV=1 CANONICAL=A0A8V0ZCB5-1" }, "locus": { "chromosome": "10", "start_pos": 12831047, "end_pos": 12828584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047995.1", "url": "https://www.ensembl.org/id/ENSGALT00010047995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028331.1", "url": "https://www.ensembl.org/id/ENSGALP00010028331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415486", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415486", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HX37-1", "protein_name": "Peroxisomal membrane protein 11A isoform X1", "gene_name": "Pex11a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDAFVRFANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVMKLKSLESSVSTGRKWFRLGNVVHAIQATEQSIQVTDLVPRLCLTLANLNRVVYYICDTVLWVKSVGLTSGVNREKWQMWATRHYYYFLLMSLVRDLYEILLQMERVASDRAKRERSSQGSPGYSVVHEDTDWLQSFLRLLFHSLRQHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLVSSVAGLITVMYPQLKLKTR", "length": 246 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1U2I9-1", "protein_name": "Peroxisomal biosis factor 11 alpha", "gene_name": "PEX11A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADKEKVVMKLKKLEASVSTGRKWFRVGNVVHALQATRESIHATDLVPRFCLTLASLNRVGYFICDTILFVKSIGITSGINKETWQVWAARYYCSSLLLSLVRDLYEISLQMEQVAHDRAKREKSPTQDPFGYSVADEETEWLQSFLLLLFRSLKKHPPLLLDTVKNFCDILNPLDQLGIYKSNAGIIGLGGLVSSLAGIITLAYPQMKLKIH", "length": 247 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O70597-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "Pex11a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR", "length": 246 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75192-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR", "length": 247 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0VCP2-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAFIRFTNQTQGRDRLFRATQYTCMLLRYLLEPKADNEKVVMKLKKLESSVSTGRKWFRLGNVVHALQATQQSVRATDLVPRICLTLASLNRVIYFICDTVLFVRSTGLASGVNKEKWRRWAARYYYYSLLLSLVRDLYEVSLQMKQVAHDRAKREKSPSQDTLGYSVADEETEWLQSLLLLLFHSLKRHPPLFLDTVKNFCDILNPLDQLGIYKSNPGIIGLGGLVSSVAGIITVAYPQMKLKTQ", "length": 247 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Z211-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "Pex11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKADKEAVVLKLKRLETSVSTGRKWFRLGNVFHAIQATEQSIQAADLAPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGVNREKWQRWAARHYYYFLLLSLVRDLYEILLQMGQVARDRAKREKSSRDPPKYSVANEETEWLQSFLLLLFQSLKRHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLISSLAGLLTVVYPQLKLKAR", "length": 246 }, "evidence": [ { "id": "A0A8V0ZCB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" }, { "name": "regulation of peroxisome size", "id": "GO:0044375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC22-1", "uniprot_ac": "A0A8V0ZC22", "uniprot_id": "A0A8V0ZC22_CHICK", "mass": { "chemical_mass": 92757.0, "monoisotopic_mass": 92757.0 }, "refseq": {}, "gene_names": [ { "name": "VWCE", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ] } ], "protein_names": [ { "name": "von Willebrand factor C and EGF domains", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VWCE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22", "locus": { "chromosome": "5", "start_pos": 265792, "end_pos": 271149, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019771", "url": "https://www.ensembl.org/id/ENSGALG00010019771" } ] } } ], "crossref": [ { "id": "A0A8V0ZC22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748485", "url": "https://www.ncbi.nlm.nih.gov/gene/101748485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4S4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC22", "url": "https://www.orthodb.org/?gene=A0A8V0ZC22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC27", "url": "https://www.orthodb.org/?gene=A0A8V0ZC27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI09", "url": "https://www.orthodb.org/?gene=A0A8V0ZI09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4S4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVALLVRAACASLLLPGGQARVYSGRKKPASFAVERRHVGPHICFSAFGSGCCPGWMLAPGSGQCVLPLCSFGCGSGFCVAPNLCSCPDGERGVTCPEPLGNCGEYGCDLSCNHGGCQEVARVCPLGFSMVETDTGVRCNDTDECLATPCQHRCKNSVGSYRCSCRPGYHLHGNRHSCVGECRAPSLRPRAIAAAPRAPRHVNECRQPGERRACQHACHNTPGSFLCSCRPGYRLSRDRVSCEGFPKAILAPSPILQSLQHPPTLVLLPPGAGGPLPLPSPHLPAAAPGTSVPPSSPRDAVQPPPGTPTSAPLCWHRGAPREPGARWTEPGCQSCSCQGGQVLCEAITCLVPCSHPLPAPAGGCCPSCTGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSPSLPPSCPAKCSFRGRTYAHGARFSLDGDECTTCVCRSGEVECSFAPCPVLDCPQQQRQLRPGQCCFSCKDPPRPSGCFVDDNGVEFPIGQIWSPGDPCELCVCQADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQGTTSICGCPDVASVPNVGHGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDGEEEEGCWISEPGRPGTAGDGALRCAVGCAEQTRGGDTSLSSGHGDPRPFTTPWCQRLWGWGASALPPPNKATPVFMLQAPPCAHPTQPRLGLETRGTA", "length": 890, "header": "tr|A0A8V0ZC22-1|A0A8V0ZC22_CHICK Isoform 1 of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#A0A8V0Z4S4-1", "sequence": { "sequence": "MLVALLVRAACASLLLPGGQARVYSGRKKPASFAVERRHVGPHICFSAFGSGCCPGWMLAPGSGQCVLPLCSFGCGSGFCVAPNLCSCPDGERGVTCPEPLGNCGEYGCDLSCNHGGCQEVARVCPLGFSMVETDTGVRCNDINECLSAACEGPCVNTEGGFVCECGPGMQLAANRHSCQDTDECLATPCQHRCKNSVGSYRCSCRPGYHLHGNRHSCVDVNECRQPGERRACQHACHNTPGSFLCSCRPGYRLSRDRVSCEGFPKAILAPSPILQSLQHPPTLVLLPPGAGGPLPLPSPHLPAAAPGTSVPPSSPRDAVQPPPGTPTSAPLCWHRGAPREPGARWTEPGCQSCSCQGGQVLCEAITCLVPCSHPLPAPAGGCCPSCTGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSASPPNCCSCQPGGVLPEEIEWLRVAVTHAWGPGGGSAPRLSPRCLPPAQQNAASVVGPTRTEPASAWMGTSAPPASAGAGRWSAPLPRARCWTVPSSSGSCAPGSAASAARTPRAPQAASWTTMGSSFPLDRSGLRVIPADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQADGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDVDMDT", "length": 831, "header": "tr|A0A8V0Z4S4-1|A0A8V0Z4S4_CHICK Computationally mapped isoform of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "locus": { "chromosome": "5", "start_pos": 270881, "end_pos": 266122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047760.1", "url": "https://www.ensembl.org/id/ENSGALT00010047760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028239.1", "url": "https://www.ensembl.org/id/ENSGALP00010028239.1" } ] } }, { "isoform_ac": "A0A8V0ZBE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#A0A8V0ZBE4-1", "sequence": { "sequence": "MLVALLVRAACASLLLPGGQARVYSGRKKPASFAVERRHVGPHICFSAFGSGCCPGWMLAPGSGQCVLPLCSFGCGSGFCVAPNLCSCPDGERGVTCPEPLGNCGEYGCDLSCNHGGCQEVARVCPLGFSMVETDTGVRCNDINECLSAACEGPCVNTEGGFVCECGPGMQLAANRHSCQDTDECLATPCQHRCKNSVGSYRCSCRPGYHLHGNRHSCVDVNECRQPGERRACQHACHNTPGSFLCSCRPGYRLSRDRVSCEGFPKAILAPSPILQSLQHPPTLVLLPPGAGGPLPLPSPHLPAAAPGTSVPPSSPRDAVQPPPGTPTSAPLCWHRGAPREPGARWTEPGCQSCSCQGGQVLCEAITCLVPCSHPLPAPAGGCCPSCTGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSASPPNCCSCQPAKCSFRGRTYAHGARFSLDGDECTTCVCRSGEVECSFAPCPVLDCPQQQRQLRPGQCCFSCKDPPRPSGCFVDDNGVEFPIGQIWSPGDPCELCVCQADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQADGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDVDMDT", "length": 800, "header": "tr|A0A8V0ZBE4-1|A0A8V0ZC22_CHICK Computationally mapped isoform of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "locus": { "chromosome": "5", "start_pos": 270881, "end_pos": 266122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047768.1", "url": "https://www.ensembl.org/id/ENSGALT00010047768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028243.1", "url": "https://www.ensembl.org/id/ENSGALP00010028243.1" } ] } }, { "isoform_ac": "A0A8V0ZC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#A0A8V0ZC22-1", "sequence": { "sequence": "MLVALLVRAACASLLLPGGQARVYSGRKKPASFAVERRHVGPHICFSAFGSGCCPGWMLAPGSGQCVLPLCSFGCGSGFCVAPNLCSCPDGERGVTCPEPLGNCGEYGCDLSCNHGGCQEVARVCPLGFSMVETDTGVRCNDTDECLATPCQHRCKNSVGSYRCSCRPGYHLHGNRHSCVGECRAPSLRPRAIAAAPRAPRHVNECRQPGERRACQHACHNTPGSFLCSCRPGYRLSRDRVSCEGFPKAILAPSPILQSLQHPPTLVLLPPGAGGPLPLPSPHLPAAAPGTSVPPSSPRDAVQPPPGTPTSAPLCWHRGAPREPGARWTEPGCQSCSCQGGQVLCEAITCLVPCSHPLPAPAGGCCPSCTGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSPSLPPSCPAKCSFRGRTYAHGARFSLDGDECTTCVCRSGEVECSFAPCPVLDCPQQQRQLRPGQCCFSCKDPPRPSGCFVDDNGVEFPIGQIWSPGDPCELCVCQADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQGTTSICGCPDVASVPNVGHGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDGEEEEGCWISEPGRPGTAGDGALRCAVGCAEQTRGGDTSLSSGHGDPRPFTTPWCQRLWGWGASALPPPNKATPVFMLQAPPCAHPTQPRLGLETRGTA", "length": 890, "header": "tr|A0A8V0ZC22-1|A0A8V0ZC22_CHICK Isoform 1 of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "locus": { "chromosome": "5", "start_pos": 270881, "end_pos": 265795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047739.1", "url": "https://www.ensembl.org/id/ENSGALT00010047739.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028232.1", "url": "https://www.ensembl.org/id/ENSGALP00010028232.1" } ] } }, { "isoform_ac": "A0A8V0ZC27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#A0A8V0ZC27-1", "sequence": { "sequence": "MLVALLVRAACASLLLPGGQARVYSGRKKPASFAVERRHVGPHICFSAFGSGCCPGWMLAPGSGQCVLPLCSFGCGSGFCVAPNLCSCPDGERGVTCPEPLGNCGEYGCDLSCNHGGCQEVARVCPLGFSMVETDTGVRCNDINECLSAACEGPCVNTEGGFVCECGPGMQLAANRHSCQDTDECLATPCQHRCKNSVGSYRCSCRPGYHLHGNRHSCVDVNECRQPGERRACQHACHNTPGSFLCSCRPGYRLSRDRVSCEGFPKAILAPSPILQSLQHPPTLVLLPPGAGGPLPLPSPHLPAAAPGTSVPPSSPRDAVQPPPGTPTSAPLCWHRGAPREPGARWTEPGCQSCSCQGGQVLCEAITCLVPCSHPLPAPAGGCCPSCTGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSASPPNCCSCQPGGVLPEEIEWLRVAVTHAWGPGGGSAPRLSPRCLPPAQQNAASVVGPTRTEPASAWMGTSAPPASAGAGRWSAPLPRARCWTVPSSSGSCAPGSAASAARTPRAPQAASWTTMGSSFPLDRSGLRVIPADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGDGDSRGRGDGTGLRALQPHSRPTGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQADGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDVDMDT", "length": 855, "header": "tr|A0A8V0ZC27-1|A0A8V0ZC27_CHICK Computationally mapped isoform of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "locus": { "chromosome": "5", "start_pos": 270881, "end_pos": 266122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047753.1", "url": "https://www.ensembl.org/id/ENSGALT00010047753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028237.1", "url": "https://www.ensembl.org/id/ENSGALP00010028237.1" } ] } }, { "isoform_ac": "A0A8V0ZI09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22/entry#A0A8V0ZI09-1", "sequence": { "sequence": "PRGTPTRSASRRRQRVPAAGRAPCVPARVPQHTGQLPLLLPARLPAQQGQGVLRRLPQGHPGALPHPAVPAAPPHAGPTPSRSGGTPPAPFSSPPRRGTGHVRSSLLPSRCRPAAPWDSHLGPSLLAPRGSPGAGSSLDGAGVPELQLPGCLSNGVAHAEGEVFTPSDGNCTICVCLAGNISCISPECPPGSCPSASPPNCCSCQPAKCSFRGRTYAHGARFSLDGDECTTCVCRSGEVECSFAPCPVLDCPQQQRQLRPGQCCFSCKDPPRPSGCFVDDNGVEFPIGQIWSPGDPCELCVCQADGSVSCKRTDCVETCPYPIHIPGQCCPDCSAGCTYMGRIFYNNETFPSLLDPCLSCICLLGSVACSPVDCAIFCTYPFHPEGECCPVCKDCNYEGRKVVNGQSFSPEGRPCTRCTCQLGEVSCEERPCPQSCTEPTACCPPCQADGQLQSSDTSPSLSPSPTPQPSSQSSSPSPSPSPSSSPSPSHEGTPQPPRHRLAQVLLHTTPLNPSLGGEPPPNAPSPPSGCPGEATGSPALSSSPSSRQDAQKHPEDVDMDT", "length": 561, "header": "tr|A0A8V0ZI09-1|A0A8V0ZI09_CHICK Computationally mapped isoform of von Willebrand factor C and EGF domains OS=Gallus gallus OX=9031 GN=VWCE PE=4 SV=1 CANONICAL=A0A8V0ZC22-1" }, "locus": { "chromosome": "5", "start_pos": 269416, "end_pos": 266122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047725.1", "url": "https://www.ensembl.org/id/ENSGALT00010047725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028225.1", "url": "https://www.ensembl.org/id/ENSGALP00010028225.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 701, "start_aa": "Thr", "end_pos": 701, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 180, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC22" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 370, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 701 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"MSSELDFKKITPSQKFIMGDLQRLLNQGEYALFASVPMFESRFVQINQRGELINLHNRPTCVTIGVCAASSPMPSGMLLAHKVPVSPQEIMANLQKFSEHPSQVEQLALSRFLPLKFVELSVHSTDKKQLMLKLVNGRSYYLELCAPPDQQQQLFHHWLKLISLLKRPEDTSNTNKLLLNKPPPTRVEGEGQPSAAPRKQSG", "length": 202, "header": "tr|A0A8V0ZBH3-1|A0A8V0ZBH3_CHICK Isoform 1 of Golgi associated RAB2 interactor protein-like Rab2B-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZBH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH3/entry#A0A8V0ZBH3-1", "sequence": { "sequence": "MSSELDFKKITPSQKFIMGDLQRLLNQGEYALFASVPMFESRFVQINQRGELINLHNRPTCVTIGVCAASSPMPSGMLLAHKVPVSPQEIMANLQKFSEHPSQVEQLALSRFLPLKFVELSVHSTDKKQLMLKLVNGRSYYLELCAPPDQQQQLFHHWLKLISLLKRPEDTSNTNKLLLNKPPPTRVEGEGQPSAAPRKQSG", "length": 202, "header": "tr|A0A8V0ZBH3-1|A0A8V0ZBH3_CHICK Isoform 1 of Golgi associated RAB2 interactor protein-like Rab2B-binding domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZBH3-1" }, "locus": { "chromosome": "5", "start_pos": 28559539, "end_pos": 28556142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048428.1", "url": "https://www.ensembl.org/id/ENSGALT00010048428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028551.1", "url": "https://www.ensembl.org/id/ENSGALP00010028551.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH3" }, { "id": "PF12480", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgi associated RAB2 interactor protein-like Rab2B-binding", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 171, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBI2-1", "uniprot_ac": "A0A8V0ZBI2", "uniprot_id": "A0A8V0ZBI2_CHICK", "mass": { "chemical_mass": 32835.0, "monoisotopic_mass": 32835.0 }, "refseq": { "ac": "NP_001269306", "name": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" }, "gene_names": [ { "name": "ALKBH3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "name": "ALKBH3", "type": "synonym", "evidence": [ { "id": "NP_001269306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" } ] } ], "protein_names": [ { "name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.33", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.54", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#names_and_taxonomy" } ] }, { "name": "Alkylated DNA repair protein alkB homolog 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#names_and_taxonomy" } ] }, { "name": "alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase", "type": "synonym", "evidence": [ { "id": "NP_001269306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" } ] }, { "name": "alkB, alkylation repair homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001269306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" } ] }, { "name": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001269306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267660.12972.1, SRR13267649.283585.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001269306.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001269306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306" } ] }, { "annotation": "Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons. Requires molecular oxygen, alpha-ketoglutarate and iron.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2#function" }, { "database": "UniProtKB", "id": "ARBA00054625", "url": "https://www.uniprot.org/uniprotkb/ARBA00054625#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALKBH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2", "locus": { "chromosome": "5", "start_pos": 21198808, "end_pos": 21182397, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019592", "url": "https://www.ensembl.org/id/ENSGALG00010019592" } ] } } ], "crossref": [ { "id": "A0A8V0ZBI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "423169", "url": "https://www.ncbi.nlm.nih.gov/gene/423169", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037151", "url": 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}, { "id": "PTHR31212:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31212:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001269306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "30299", "url": "https://www.rhea-db.org/rhea/30299", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49516", "url": "https://www.rhea-db.org/rhea/49516", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70435", "url": "https://www.rhea-db.org/rhea/70435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70447", "url": "https://www.rhea-db.org/rhea/70447", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70471", "url": "https://www.rhea-db.org/rhea/70471", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERRRRARVQGGWAGGAAGRLAAPKAPEAGSRSPAGGGQAWGGRDQLRSRKQFVFEKPSEVERRVPEAGVIDKPGVYELSTEPSGVSRIHLVPGFIDSEQADWMFEQLLQDVPWGQRTHTRQEGSFEEPRLTSWYGELPYTYSRITMQPNPNWHPVLTMLKEQIEEFTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGKNPVIASLSFGAIRTFEMRKKPSPEENGDYTYVERLRIPLDHGTLLMMEGATQEDWQHRVPKEYHSRDARINLTFRIIYPEPDRVWK", "length": 286, "header": "tr|A0A8V0ZBI2-1|A0A8V0ZBI2_CHICK Isoform 1 of Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Gallus gallus OX=9031 GN=ALKBH3 PE=3 SV=1 CANONICAL=A0A8V0ZBI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#A0A8V0ZBH7-1", "sequence": { "sequence": "MNDWAELKTFTKQSSKLCGPSFVFSLGRSTVKSSWLSRLGGALGGFSFFRRSPGTPVERRVPEAGVIDKPGVYELSTEPSGVSRIHLVPGFIDSEQADWMFEQLLQDVPWGQRTHTRQEGSFEEPRLTSWYGELPYTYSRITMQPNPNWHPVLTMLKEQIEEFTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGKNPVIASLSFGAIRTFEMRKKPSPEENGDYTYVERLRIPLDHGTLLMMEGATQEDWQHRVPKEYHSRDARINLTFRIIYPEPDRVWK", "length": 281, "header": "tr|A0A8V0ZBH7-1|A0A8V0ZBI2_CHICK Computationally mapped isoform of Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Gallus gallus OX=9031 GN=ALKBH3 PE=3 SV=1 CANONICAL=A0A8V0ZBI2-1" }, "locus": { "chromosome": "5", "start_pos": 21197408, "end_pos": 21182922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047266.1", "url": "https://www.ensembl.org/id/ENSGALT00010047266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028015.1", "url": "https://www.ensembl.org/id/ENSGALP00010028015.1" } ] } }, { "isoform_ac": "A0A8V0ZBI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#A0A8V0ZBI2-1", "sequence": { "sequence": "MAERRRRARVQGGWAGGAAGRLAAPKAPEAGSRSPAGGGQAWGGRDQLRSRKQFVFEKPSEVERRVPEAGVIDKPGVYELSTEPSGVSRIHLVPGFIDSEQADWMFEQLLQDVPWGQRTHTRQEGSFEEPRLTSWYGELPYTYSRITMQPNPNWHPVLTMLKEQIEEFTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGKNPVIASLSFGAIRTFEMRKKPSPEENGDYTYVERLRIPLDHGTLLMMEGATQEDWQHRVPKEYHSRDARINLTFRIIYPEPDRVWK", "length": 286, "header": "tr|A0A8V0ZBI2-1|A0A8V0ZBI2_CHICK Isoform 1 of Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Gallus gallus OX=9031 GN=ALKBH3 PE=3 SV=1 CANONICAL=A0A8V0ZBI2-1" }, "locus": { "chromosome": "5", "start_pos": 21197408, "end_pos": 21182426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047274.1", "url": "https://www.ensembl.org/id/ENSGALT00010047274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028020.1", "url": "https://www.ensembl.org/id/ENSGALP00010028020.1" } ] } }, { "isoform_ac": "A0A8V0ZHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2/entry#A0A8V0ZHF8-1", "sequence": { "sequence": "MLQLSSCPVVCFSLWRYIVHLPGVSRDGSGLCLAELCQVCEHLVLTLPCLIAFQVERRVPEAGVIDKPGVYELSTEPSGVSRIHLVPGFIDSEQADWMFEQLLQDVPWGQRTHTRQEGSFEEPRLTSWYGELPYTYSRITMQPNPNWHPVLTMLKEQIEEFTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGKNPVIASLSFGAIRTFEMRKKPSPEENGDYTYVERLRIPLDHGTLLMMEGATQEDWQHRVPKEYHSRDARINLTFRIIYPEPDRVWK", "length": 279, "header": "tr|A0A8V0ZHF8-1|A0A8V0ZHF8_CHICK Computationally mapped isoform of Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Gallus gallus OX=9031 GN=ALKBH3 PE=3 SV=1 CANONICAL=A0A8V0ZBI2-1" }, "locus": { "chromosome": "5", "start_pos": 21197408, "end_pos": 21183411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047256.1", "url": "https://www.ensembl.org/id/ENSGALT00010047256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028008.1", "url": "https://www.ensembl.org/id/ENSGALP00010028008.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423169", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B3Y6-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "ALKBH3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDKRRRARVQGAWAGPAKSQAIAQPATTTENRLPQRPGQTWMNKEHLSDRQFVFKEPQEVVRRAPEPRVIDKEGVYEISLSPTGISRVCLYPGFVDLKEADWVLEQLCRDVPWKQRTGIREDVTYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLLTLKNQIEQNTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRMFEMRKKPPPEENGDYTYVDRVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRINLTFRTVYPDPQGARW", "length": 285 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M3U9-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "Alkbh3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDKRRRARVQGAWAAPAKSQPTAQPGTAARNHLSQTPGQAWRSKEQQLPDREFVFKEPQLVVRTAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILERLCQDVPWKQRMGIREDITYPQPRLTAWYGELPYTYSRITMEPNPHWHPILCTLKSRIEKNTGHTFNSLLCNLYRDEKDSVDWHSDDEPSLGSFPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTIYPDPRGASW", "length": 286 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1QRD8-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "alkbh3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDKRQRARVQGSWAKPVQKPQRPSVQDVQSASASGSWKSGPQSFEFHQPADPIRKVPAEKVIENAGDYEISQGPSGVSRLRLIPGFLLQEEADWMFSKLLAELPWSQKTNYRMMGDAYEEPRLTCWYGELPYTYSRSTMEANAQWHPVLATLRLAVEQKSAHKFNSLLCNLYRDGKDSIGWHSDSEPSLGPQPIIASLSLGDTRVFSLRKQPLPEDKGDFTYVERIRVPLAHGTLLLMEGCTQADWQHQVAKEYHDRGPRINLTFRTIYPEPQRSGGRFVT", "length": 282 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32L00-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "ALKBH3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDKRRRARVQGAWAGPAKSQATAQPAPTAENNLQQRPGKAWMNKEQHLSDRQFVFKEPQEGVRRAPEPRVIEKEGVYEISMSPTGISRVCLCPGFVDLKEADSVFEQLCRDVPWKQRTGIRDDVTYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLLMLKNQIEENTGHSFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRMFEMRKKPPPEDNGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRINLTFRTVYPDPRGAHW", "length": 286 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIC8-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "Alkbh3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKRQRARVQGAWATPTKSQSAARPATPARSRPSQTPGPSWRSKEQQQCDRRFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILERLCQDVPWKQRMGIREDITYPQPRLTAWYGELPYTYSRVTMEPNPHWLPVLWTLKSRIEENTGHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRERRVNLTFRTVYPDPRGAPGDTSAELPLR", "length": 295 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K1E6-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "Alkbh3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDKRQRARVQGGWATPTKSQSATQPASPARSRLSQTAGPAWRSKEQQQCDRQFVFKEPQLVVRAAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDLKEADWILEQLCKDVPWKQRMGIREDVTYPQPRLTAWYGELPYTYSRITMEPNPHWLPVLWTLKSRIEENTSHTFNSLLCNFYRDEKDSVDWHSDDEPSLGSCPVIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRQPRVNLTFRTVYPDPRGAPR", "length": 286 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96Q83-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "ALKBH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEKRRRARVQGAWAAPVKSQAIAQPATTAKSHLHQKPGQTWKNKEHHLSDREFVFKEPQQVVRRAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLCQDVPWKQRTGIREDITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW", "length": 286 }, "evidence": [ { "id": "A0A8V0ZBI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZBI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "mRNA N1-methyladenosine dioxygenase activity", "id": "GO:1990930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "broad specificity oxidative DNA demethylase activity", "id": "GO:0035516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA alkylation repair", "id": "GO:0006307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30299", "name": "", "equation": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RK82-1", "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "30299", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30299" } ] }, { "id": "49516", "name": "", "equation": "an N(1)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1" ], "evidence": [ { "id": "49516", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49516" } ] }, { "id": "70435", "name": "", "equation": "an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70435" } ] }, { "id": "70447", "name": "", "equation": "an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70447", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70447" } ] }, { "id": "70471", "name": "", "equation": "a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxycytidine in single-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70471", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70471" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZBI2", "gene_name": "ALKBH3", "activity": [ { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.54", "activity": "an N(1)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.54", "activity": "", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] } ] }, { "uniprot_ac": "A0A8V0ZID8", "gene_name": "ALKBH2", "activity": [ { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ] } ] }, { "uniprot_ac": "F6RK82", "gene_name": "ALKBH1", "activity": [ { "ec_number": "1.14.11.51", "activity": "an N(6)-methyl-2'-deoxyadenosine in DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.51", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 278, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.33", "ec_name": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "1.14.11.33", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.33" }, { "id": "1.14.11.33", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.33" } ] }, { "ec_number": "1.14.11.54", "ec_name": "an N(1)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "1.14.11.54", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.54" }, { "id": "1.14.11.54", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.54" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31043:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31043:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26186", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26186", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28126", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28126", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2028269", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2028269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEWERLFAQSRAVPPHAQRRHGVPERSVPFQCVLKCLEGSVVKQRSPAELQLRLSLFDAAHRHFFGHTWHSSTRTPCSAPGQPPRVLFNEAVYFHTSLSHPSITAVVEVVAVAPTPEGLSRDVSCGFGLIPLFDSRREPSDLAAKGRALKLYHGTPRALLHPLLQDPLEKNKYVTIMENSHLEYTLKPHLPLEKIFHLLPENLLVSGLQKIPGLLPAHGDTGDAFLKPRLMGTTPCYLDQLCVRLHPSLEEFEEGLLEQLSSDRLLKQEVGSTLCVQERRLRVGVHNGLRFVQAPQVAVLQPAAEVARGQSTNPTDSAAEQALLLRSRLQLSEMVLHPAFGVCFQLEYVVCAAAKAAAGSALGPAAAMHTVRWALWSPFLGATSSPVLLSLRGGAHPSPGQTLVYRNPADSESSQQVKRIASGCVQFHVSTDAEHGVTSTDVSSKAGKELQEPPTPSLSLRSPLRPVASTQGPGLSLSQLLASPQGRDERAVPRGRSAPMPRPCSTQRDGCTEHTAGITHLEADLCSGSPHVDASSGEHLWELPFAPTQPPITAVGPPAGSTALSRASLALLHSSGFPEILDGNKEPVELTEPLDPACFSPRLEEVDALQSNEIILQFLAFSRAPQDAVEGIWPTTVFLTFQFYRFPAVTTQRLQLLDVDGERAAGAAVPAQVLLQLNKDGTPSTGAPGLQLRYVVDPTFLRPGEQRVFVHYLAEHSLQVDIWDGDSLLLVGSAAVKLKPLLRQGRPAVRTLHELEVATTEYEQDAPPAAGRDVLRPLGVRMAVRGHLHLCLANIGHRCEETPVSPRHPSLSHTHLVPSQGSGCLQSHHAGGDVRVSRARRLAEVDGELAAILRSHRLEQSPDPLHAPHEAAAVQQRKLRCLAVVQQQKDAGWRIPQRMGWCEQRMQYLQVIDAYRERTKRRCISQLLSQAITITHTVYAMLGTAEFFEFALKNPYSVQHTVTVEVDHPELSVIVDPREWRHFKELTQTATPLEEDMFHLRDDLRPQVYLRPKETVHIPFRYQTFSAEPAVAAVLGPVGLSKDEDAGRMQEEPRAAQMRPIQVAFRVSGGKPIALLQVKVEPRPHVVDQTFRFYHPELTFLKKAIRLPPRHTLPGALAGMQGNEPEVYVRCSDPNVISLHPWQHPDLLAPGNENETLAVVKAGLPSIPMKTGCIVLGPGEPQDVFLKVAGGPSPQIKTFFVAIYTDPWLAAPLRIWQFHLHSLQRLDVSCTAGQLSRLAVPLRGTRTLRRVKAFCSHPHELKVDPAGVFILPPNGVLDLFVGVRPRRAGSRFLYLNLVDVECHQLLSSWLLCITCRQPLISKAFEITIPVGSGKGSNKRITYTNPYPTRRLYFLVTSRPDLLQFKEDSFEVAGGEVYTIGLRFAPSQSVGEEEILIHINDHEDKNEETFCVKVIYY", 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"length": 1417, "header": "tr|A0A8V0ZBK5-1|A0A8V0ZBK5_CHICK Isoform 1 of Nephrocystin 4 OS=Gallus gallus OX=9031 GN=NPHP4 PE=1 SV=1 CANONICAL=A0A8V0ZBK5-1" }, "locus": { "chromosome": "21", "start_pos": 702129, "end_pos": 681998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047329.1", "url": "https://www.ensembl.org/id/ENSGALT00010047329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028045.1", "url": "https://www.ensembl.org/id/ENSGALP00010028045.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 116, "start_aa": "Thr", "end_pos": 116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2028269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2028269", "resource": "Reactome", "description": "Signaling by Hippo" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "ribbon synapse", "id": "GO:0097470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "photoreceptor distal connecting cilium", "id": "GO:0120206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120206", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" }, { "name": "positive regulation of bicellular tight junction assembly", "id": "GO:1903348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903348", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" }, { "id": "PF26186", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NPHP4 C2-like", "eco_id": "ECO_0000259", "start_pos": 568, "end_pos": 798, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK5" }, { "id": "PF26190", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26190" }, { "id": "PF26189", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26189" }, { "id": "PF26015", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26015" }, { "id": "PF26187", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26187" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NPHP4 Ig-like", "eco_id": "ECO_0000259", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZBM0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0", "locus": { "chromosome": "21", "start_pos": 1897479, "end_pos": 1832339, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020083", "url": "https://www.ensembl.org/id/ENSGALG00010020083" } ] } } ], "crossref": [ { "id": "419400", "url": "https://www.ncbi.nlm.nih.gov/gene/419400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLCCWVHSRTKAGKTQAPTCLPGDLCVLTDLQPSPCQHTCCDGTSVMEGSSEPGSGGEEEPTLIPFLEEEGNGTAAQSSDPGEHEEEYKLEEDLSDDGTMGNEVTSEGDGDKSEPSMDSLEHGLDDVTSSQALKSADRICLFPLPRNLKELSDIAKEKELVVQKIRDELTACQLRIKALEKQLENVDIETEEEKEAGNVAAVFRLQAMHRRLCTELEDEKSFELKIALTLKENMLEMWRIEMQQGKYEILHKQSKKDEEEREMQYQEQAEVRIRREKIAALKAEENQLSLKKKEEKAQKEYEKRHKKMLDGAKRNHDKAVYFLRKSMARIHEKNAKEEAKTQEHMERRIQAVLSLKNSITSNREKLQALQAWNQAMAKKQEMTMREAILAEGGNVAKEIFLHKRLLQHEKEKQAFIEQQKSRKIEIVSKILKEKASSCKQKNQQLCTKAIKSGGKCKDSLLWRKKAWRYIEKTCKHPAGALPQESWYSPSVCSPAGERTASVGECSETVPHDVPCESEEGEKERDEIPAEPELPGLLSQECDLHKISKEEMDTKHLDTKITKTVILEDRKEEFPTRIFNKGTVSGHEHQGRSFYSKPSCIHFKDFDVGKTYKKKIVLINASYSINYCKPVGISKWLKDFISIQFDPPGKMSAGMSCEVGITFKPVINENLEGEVMFMAQTGFFSVPLKCTAKTCILALDKVLVDFGTHVVGETISRTVNLTNTGALGTRFKVQTLGGDSSRCGATAESSTTRTVTQLCSDSAPERKDSNSSVTSVLEKKEQTCLDGSEEPTCCVAQVEQQRTETSSTEQLTQDAFNFSSDKDMDNAHDLMACSPEEIPIEIMLGKVTEGEIGPFSSVKLQIIFMPSIPGDVRAEFEIVFDNSDCKPLYFSATGVAIDVPVWVPNPNVDLKICMYDRLYQDCIVIRSRAKTTLNLKFEVCKELSKHMKLLPKTGYILPRSSFRVQLKFLPRHSLPGDAGSCFNEETGVLEAPVTIQIADNTKQINFTVHAIVTTTDLVISPAEINFGYCTIYEAVRTNVTLTNKSILPQEFGFVRLPEFVEIQPNDGFGVLLPLESLTLHVIFKANKAKEYSFELTCKSEVNRQFKLSCRAVGVHPPLELSHSLVQFAATALNDVSTATLYVMNSHVSANIFTHAVPRIGNGEVAPVGPTSFEFYVPEDCPVTITPSVGTVLPGKKSLIQVSFRPTLSDQLIREEAAQRLCGAAATGAEIQEIKKDEKTERKKLSVPLSRRQSSRQVVRTGSVKCLSSSYKSEQPECKEIKPDSEAYIAAQAFLTRNFRGKFEKYTIPCFVASGHVDEKRGSESLSFSPCNTLYLELHCPAVAPSVVVTSDNGKNTVDFGDVAVGQTILKETTIQNISPENLELRFSVLNPSGPFLLVRPVRMLEPGEIRTLIVSFSPNKNKLFLEMLDIRTAKNNLPLRITGYGVVPSTVCSVEVLDMGYVLTGEKATSTFKVQNTSTLTLRYSIHLDSFSSARDKDQQRVPSFLMSSLQGAETVETENCNGVSAFSVLPAEGEICGGESQDFIVTFSPEREGLYYSECLKVVLFGKKTAHVIQLKGAARDHPMFVEGGIPLDVPIESLAVTLPPSPKKALKEERQEPVKSIVLLLEHVEGENALPPAVAELKVGAIQTAQFASKKNVEFSFDNLSHLQKKGFAIEPVKGKVDRGHVKCISVFWVPPADFDASAPLVETAFLNLKGDIKESYRILFVATAVSAPTS", "length": 1737, "header": "tr|A0A8V0ZBM0-1|A0A8V0ZBM0_CHICK Isoform 1 of Cilia and flagella associated protein 74 OS=Gallus gallus OX=9031 GN=CFAP74 PE=4 SV=1 CANONICAL=A0A8V0ZBM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0/entry#A0A8V0ZBM0-1", "sequence": { "sequence": "MHLCCWVHSRTKAGKTQAPTCLPGDLCVLTDLQPSPCQHTCCDGTSVMEGSSEPGSGGEEEPTLIPFLEEEGNGTAAQSSDPGEHEEEYKLEEDLSDDGTMGNEVTSEGDGDKSEPSMDSLEHGLDDVTSSQALKSADRICLFPLPRNLKELSDIAKEKELVVQKIRDELTACQLRIKALEKQLENVDIETEEEKEAGNVAAVFRLQAMHRRLCTELEDEKSFELKIALTLKENMLEMWRIEMQQGKYEILHKQSKKDEEEREMQYQEQAEVRIRREKIAALKAEENQLSLKKKEEKAQKEYEKRHKKMLDGAKRNHDKAVYFLRKSMARIHEKNAKEEAKTQEHMERRIQAVLSLKNSITSNREKLQALQAWNQAMAKKQEMTMREAILAEGGNVAKEIFLHKRLLQHEKEKQAFIEQQKSRKIEIVSKILKEKASSCKQKNQQLCTKAIKSGGKCKDSLLWRKKAWRYIEKTCKHPAGALPQESWYSPSVCSPAGERTASVGECSETVPHDVPCESEEGEKERDEIPAEPELPGLLSQECDLHKISKEEMDTKHLDTKITKTVILEDRKEEFPTRIFNKGTVSGHEHQGRSFYSKPSCIHFKDFDVGKTYKKKIVLINASYSINYCKPVGISKWLKDFISIQFDPPGKMSAGMSCEVGITFKPVINENLEGEVMFMAQTGFFSVPLKCTAKTCILALDKVLVDFGTHVVGETISRTVNLTNTGALGTRFKVQTLGGDSSRCGATAESSTTRTVTQLCSDSAPERKDSNSSVTSVLEKKEQTCLDGSEEPTCCVAQVEQQRTETSSTEQLTQDAFNFSSDKDMDNAHDLMACSPEEIPIEIMLGKVTEGEIGPFSSVKLQIIFMPSIPGDVRAEFEIVFDNSDCKPLYFSATGVAIDVPVWVPNPNVDLKICMYDRLYQDCIVIRSRAKTTLNLKFEVCKELSKHMKLLPKTGYILPRSSFRVQLKFLPRHSLPGDAGSCFNEETGVLEAPVTIQIADNTKQINFTVHAIVTTTDLVISPAEINFGYCTIYEAVRTNVTLTNKSILPQEFGFVRLPEFVEIQPNDGFGVLLPLESLTLHVIFKANKAKEYSFELTCKSEVNRQFKLSCRAVGVHPPLELSHSLVQFAATALNDVSTATLYVMNSHVSANIFTHAVPRIGNGEVAPVGPTSFEFYVPEDCPVTITPSVGTVLPGKKSLIQVSFRPTLSDQLIREEAAQRLCGAAATGAEIQEIKKDEKTERKKLSVPLSRRQSSRQVVRTGSVKCLSSSYKSEQPECKEIKPDSEAYIAAQAFLTRNFRGKFEKYTIPCFVASGHVDEKRGSESLSFSPCNTLYLELHCPAVAPSVVVTSDNGKNTVDFGDVAVGQTILKETTIQNISPENLELRFSVLNPSGPFLLVRPVRMLEPGEIRTLIVSFSPNKNKLFLEMLDIRTAKNNLPLRITGYGVVPSTVCSVEVLDMGYVLTGEKATSTFKVQNTSTLTLRYSIHLDSFSSARDKDQQRVPSFLMSSLQGAETVETENCNGVSAFSVLPAEGEICGGESQDFIVTFSPEREGLYYSECLKVVLFGKKTAHVIQLKGAARDHPMFVEGGIPLDVPIESLAVTLPPSPKKALKEERQEPVKSIVLLLEHVEGENALPPAVAELKVGAIQTAQFASKKNVEFSFDNLSHLQKKGFAIEPVKGKVDRGHVKCISVFWVPPADFDASAPLVETAFLNLKGDIKESYRILFVATAVSAPTS", "length": 1737, "header": "tr|A0A8V0ZBM0-1|A0A8V0ZBM0_CHICK Isoform 1 of Cilia and flagella associated protein 74 OS=Gallus gallus OX=9031 GN=CFAP74 PE=4 SV=1 CANONICAL=A0A8V0ZBM0-1" }, "locus": { "chromosome": "21", "start_pos": 1896630, "end_pos": 1855542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048518.1", "url": "https://www.ensembl.org/id/ENSGALT00010048518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028609.1", "url": "https://www.ensembl.org/id/ENSGALP00010028609.1" } ] } }, { "isoform_ac": "A0A8V0ZD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0/entry#A0A8V0ZD28-1", "sequence": { "sequence": "MEGSSEPGSGGEEEPTLIPFLEEEGNGTAAQSSDPGEHEEEYKLEEDLSDDGTMGNEVTSEGDGDKSEPSMDSLEHGLDDVTSSQALKSADRICLFPLPRNLKELSDIAKEKELVVQKIRDELTACQLRIKALEKQLENVDIETEEEKEAGNVAAVFRLQAMHRRLCTELEDEKSFELKIALTLKENMLEMWRIEMQQGKYEILHKQSKKDEEEREMQYQEQAEVRIRREKIAALKAEENQLSLKKKEEKAQKEYEKRHKKMLDGAKRNHDKAVYFLRKSMARIHEKNAKEEAKTQEHMERRIQAVLSLKNSITSNREKLQALQAWNQAMAKKQEMTMREAILAEGGNVAKEIFLHKRLLQHEKEKQAFIEQQKSRKIEIVSKILKEKASSCKQKNQQLCTKAIKSGGKCKDSLLWRKKAWRYIEKTCKHPAGALPQESWYSPSVCSPAGERTASVGECSETVPHDVPCESEEGEKERDEIPAEPELPGLLSQECDLHKISKEEMDTKHLDTKITKTVILEDRKEEFPTRIFNKGTVSGHEHQGRSFYSKPSCIHFKDFDVGKTYKKKIVLINASYSINYCKPVGISKWLKDFISIQFDPPGKMSAGMSCEVGITFKPVINENLEGEVMFMAQTGFFSVPLKCTAKTCILALDKVLVDFGTHVVGETISRTVNLTNTGALGTRFKVQTLGGDSSRCGATAESSTTRTVTQLCSDSAPERKDSNSSVTSVLEKKEQTCLDGSEEPTCCVAQVEQQRTETSSTEQLTQDAFNFSSDKDMDNAHDLMACSPEEIPIEIMLGKVTEGEIGPFSSVKLQIIFMPSIPGDVRAEFEIVFDNSDCKPLYFSATGVAIDVPVWVPNPNVDLKICMYDRLYQDCIVIRSRAKTTLNLKFEVCKELSKHMKLLPKTGYILPRSSFRVQLKFLPRHSLPGDAGSCFNEETGVLEAPVTIQIADNTKQINFTVHAIVTTTDLVISPAEINFGYCTIYEAVRTNVTLTNKSILPQEFGFVRLPEFVEIQPNDGFGVLLPLESLTLHVIFKANKAKEYSFELTCKSEVNRQFKLSCRAVGVHPPLELSHSLVQFAATALNDVSTATLYVMNSHVSANIFTHAVPRIGNGEVAPVGPTSFEFYVPEDCPVTITPSVGTVLPGKKSLIQVSFRPTLSDQLIREEAAQRLCGAAATGAEIQEIKKDEKTERKKLSVPLSRRQSSRQVVRTGSVKCLSSSYKSEQPECKEIKPDSEAYIAAQAFLTRNFRGKFEKYTIPCFVASGHVDEKRGSESLSFSPCNTLYLELHCPAVAPSVVVTSDNGKNTVDFGDVAVGQTILKETTIQNISPENLELRFSVLNPSGPFLLVRPVRMLEPGEIRTLIVSFSPNKNKLFLEMLDIRTAKNNLPLRITGYGVVPSTVCSVEVLDMGYVLTGEKATSTFKVQNTSTLTLRYSIHLDSFSSARDKDQQRVPSFLMSSLQGAETVETENCNGVSAFSVLPAEGEICGGESQDFIVTFSPEREGLYYSECLKVVLFGKKTAHVIQLKGAARDHPMFVEGGIPLDVPIESLAVTLPPSPKKALKEERQEPVKSIVLLLEHVEGENALPPAVAELKVGAIQTAQFASKKNVEFSFDNLSHLQKKGFAIEPVKGKVDRGHVKCISVFWVPPADFDASAPLVETAFLNLKGDIKESYRILFVATAVSAPTS", "length": 1690, "header": "tr|A0A8V0ZD28-1|A0A8V0ZD28_CHICK Computationally mapped isoform of Cilia and flagella associated protein 74 OS=Gallus gallus OX=9031 GN=CFAP74 PE=4 SV=1 CANONICAL=A0A8V0ZBM0-1" }, "locus": { "chromosome": "21", "start_pos": 1896630, "end_pos": 1860428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048523.1", "url": "https://www.ensembl.org/id/ENSGALT00010048523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028615.1", "url": "https://www.ensembl.org/id/ENSGALP00010028615.1" } ] } }, { "isoform_ac": "A0A8V0ZD32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0/entry#A0A8V0ZD32-1", "sequence": { "sequence": "MEGSSEPGSGGEEEPTLIPFLEEEGNGTAAQSSDPGEHEEEYKLEEDLSDDGTMGNEVTSEGDGDKSEPSMDSLEHGLDDVTSSQALKSADRICLFPLPRNLKELSDIAKEKELVVQKIRDELTACQLRIKALEKQLENVDIETEEEKEAGNVAAVFRLQAMHRRLCTELEDEKSFELKIALTLKENMLEMWRIEMQQGKYEILHKQSKKDEEEREMQYQEQAEVRIRREKIAALKAEENQLSLKKKEEKAQKEYEKRHKKMLDGAKRNHDKAVYFLRKSMARIHEKNAKEEAKTQEHMERRIQAVLSLKNSITSNREKLQALQAWNQAMAKKQEMTMREAILAEGGNVAKEIFLHKRLLQHEKEKQAFIEQQKSRKIEIVSKILKEKASSCKQKNQQLCTKAIKSGGKCKDSLLWRKKAWRYIEKTCKHPAGALPQESWYSPSVCSPAGERTASVGECSETVPHDVPCESEEGEKERDEIPAEPELPGLLSQECDLHKISKEEMDTKHLDTKITKTVILEDRKEEFPTRIFNKGTVSGHEHQGRSFYSKPSCIHFKDFDVGKTYKKKIVLINASYSINYCKPVGISKWLKDFISIQFDPPGKMSAGMSCEVGITFKPVLALDKVLVDFGTHVVGETISRTVNLTNTGALGTRFKVQTLGGDSSRCGATAESSTTRTVTQLCSDSAPERKDSNSSVTSVLEKKEQTCLDGSEEPTCCVAQVEQQRTETSSTEQLTQDAFNFSSDKDMDNAHDLMACSPEEIPIEIMLGKVTEGEIGPFSSVKLQIIFMPSIPGDVRAEFEIVFDNSDCKPLYFSATGVAIDVPVWVPNPNVDLKICMYDRLYQDCIVIRSRAKTTLNLKFEVCKELSKHMKLLPKTGYILPRSSFRVQLKFLPRHSLPGDAGSCFNEETGVLEAPVTIQIADNTKQINFTVHAIVTTTDLVISPAEINFGYCTIYEAVRTNVTLTNKSILPQEFGFVRLPEFVEIQPNDGFGVLLPLESLTLHVIFKANKAKEYSFELTCKSEVNRQFKLSCRAVGVHPPLELSHSLVQFAATALNDVSTATLYVMNSHVSANIFTHAVPRIGNGEVAPVGPTSFEFYVPEDCPVTITPSVGTVLPGKKSLIQVSFRPTLSDQLIREEAAQRLCGAAATGAEIQEIKKDEKTERKKLSVPLSRRQSSRQVVRTGSVKCLSSSYKSEQPECKEIKPDSEAYIAAQAFLTRNFRGKFEKYTIPCFVASGHVDEKRGSESLSFSPCNTLYLELHCPAVAPSVVVTSDNGKNTVDFGDVAVGQTILKETTIQNISPENLELRFSVLNPSGPFLLVRPVRMLEPGEIRTLIVSFSPNKNKLFLEMLDIRTAKNNLPLRITGYGVVPSTVCSVEVLDMGYVLTGEKATSTFKVQNTSTLTLRYSIHLDSFSSARDKDQQRVPSFLMSSLQGAETVETENCNGVSAFSVLPAEGEICGGESQDFIVTFSPEREGLYYSECLKVVLFGKKTAHVIQLKGAARDHPMFVEGGIPLDVPIESLAVTLPPSPKKALKEERQEPVKSIVLLLEHVEGENALPPAVAELKVGAIQTAQFASKKNVEFSFDNLSHLQKKGFAIEPVKGKVDRGHVKCISVFWVPPADFDASAPLVETAFLNLKGDIKESYRILFVATAVSAPTS", "length": 1660, "header": "tr|A0A8V0ZD32-1|A0A8V0ZD32_CHICK Computationally mapped isoform of Cilia and flagella associated protein 74 OS=Gallus gallus OX=9031 GN=CFAP74 PE=4 SV=1 CANONICAL=A0A8V0ZBM0-1" }, "locus": { "chromosome": "21", "start_pos": 1896630, "end_pos": 1860428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048529.1", "url": "https://www.ensembl.org/id/ENSGALT00010048529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028620.1", "url": "https://www.ensembl.org/id/ENSGALP00010028620.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1170, "start_aa": "Thr", "end_pos": 1170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1170", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1005, "end_pos": 1007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1376, "end_pos": 1378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1476, "end_pos": 1478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1665, "end_pos": 1667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0" }, { "id": "PF24771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 first Ig-like", "eco_id": "ECO_0000259", "start_pos": 594, "end_pos": 690, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0" }, { "id": "PF24798", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24798" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 fourth Ig-like", "eco_id": "ECO_0000259", "start_pos": 1019, "end_pos": 1115, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0" }, { "id": "PF24770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 second Ig-like", "eco_id": "ECO_0000259", "start_pos": 697, "end_pos": 899, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM0" }, { "id": "PF24778", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24778" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP74 third Ig-like", "eco_id": "ECO_0000259", "start_pos": 901, "end_pos": 1013, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1170 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1005, "end_pos": 1007 }, { "start_pos": 1038, "end_pos": 1040 }, { "start_pos": 1043, "end_pos": 1045 }, { "start_pos": 1376, "end_pos": 1378 }, { "start_pos": 1476, "end_pos": 1478 }, { "start_pos": 1665, "end_pos": 1667 }, { "start_pos": 620, "end_pos": 622 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 817, "end_pos": 819 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBM3-1", "uniprot_ac": "A0A8V0ZBM3", "uniprot_id": "A0A8V0ZBM3_CHICK", "mass": { "chemical_mass": 195032.0, "monoisotopic_mass": 195032.0 }, "refseq": { "ac": "XP_004942143", "name": "inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942143" }, "gene_names": [ { "name": "USP54", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" } ] }, { "name": "USP54", "type": "synonym", "evidence": [ { "id": "XP_004942143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942143" } ] } ], "protein_names": [ { "name": "Ubiquitin specific peptidase 54", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3/entry#names_and_taxonomy" } ] }, { "name": "inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942143" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3", "locus": { "chromosome": "6", "start_pos": 16908677, "end_pos": 16811488, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021239", "url": "https://www.ensembl.org/id/ENSGALG00010021239" } ] } } ], "crossref": [ { "id": "ENSGALG00000005232", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005232", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423746", "url": "https://www.ncbi.nlm.nih.gov/gene/423746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZIQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BU81", "url": "https://www.orthodb.org/?gene=E1BU81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22975", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22975", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22975:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22975:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU81", "url": "https://www.uniprot.org/uniprotkb/E1BU81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU81-1", "url": "https://www.uniprot.org/uniprotkb/E1BU81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWKRSYFSVGRGNVQGMFTPRSTTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRSFRQISTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDALRTALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAPHCVSHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPTPDMFGELLQNASTMGDLRNCPSNCGEKIRIRRVLMNSPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKHSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPRGTPVSTQDLPSQVDLQQYSRTCYDSEDSGREPSISSDTRTDSSTDSYPYKQAHHESVVSHFSSDSQGTVIYNVDNDAASQSSRDTGHLTDSECNQRHISKKSSLADRKRSSSRSRRKGDEAQSSGYHSEGETLKEKQAPRAAPKPSSSTSRLREFKETVSNMIHNRPQQISQTNQNAPHGGSHMDQAETRPSKSLSVHSRDWEVESTSSESKSSSSSRYRPSWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEEAGKELMENEVKEHTVQETRSSQSNVRYKRPVLSRGTQHVMDQHPHLIQRMESGYESSERNSNSPVSLDIPLSESSSTHRDIHMKRTGGLVPAWRSIPKSHSSSILEVEPTSSNGSWANSPRTFGNGGEMFAPLKSELDELQEEVARRAHEQELRRKREKEMEAAMGFNPRPSRFMDLDELQNQGRSDGFEKSMQEADSIFEESLNQEQKGDCASALALCNEAISKLRLAMHDANSSTHSRALVDKKLQISIRKARSLQDRMQHQQPSQPLPSPTCHPPQGGTVSQSTSEQTGPFQVLLSQEVPLEPNKEVEFGSSSFFHPPASCHELHSSLYPESSSLSPPESNPSNRISPNFQSASSDFHDQVPSFPYRQGLAERSARTENDAHHSVEFTDTTAAGPKEYRECCSSSKLEEVHSIAPILTPQYKSKTNTVNSGSLPTLFPCPHPPQAASPEKDNQHSPCSKLSSSPVRPSIDHLGSYREMSPATSSPSQQCSLDPLQKTDKYSRANSHEILLPSQDEYGIAEGCKSEAFSTKGHVRSLAEQFQKMHAVSQRKGTHERGWISAVCQDETSPKQIQKSSFNPSPSDYRQLIHQNQENKTQSSEKLHSTVDIRDGVVSLEGKQVASKSICSISEELCRRGGQNIVDPAPYLERHCHDGGMKQVDDGASSSMVASMPVDRWVDNVTRYYSSQKDNKNTEWLPVPGRSPSLSDQRAVGDDLSRIPVHLHPQWNQDTEQELSELESLYQTSLQASQATRPFLGRQDSARYPFDHSVSANLNVRKLHTTAGMGLSKTPTAEIERSLYGSTVSSVSKVTYTREHSREPEEEEMYSAENFRRIARSLSGTVVSNREETLVSSHSFEAPNMRKMPMETSHRSSSSTSLPFPHDPPVFPFDPQHTPNQVQHLPHDVLVPSMVGKARKPSGDQKNIIQKLLVMPDRGEAFQGEDYPGMALSYGSLPCAPRGTLSQGQKPLPNLCSGGGASNVSGHWLNRSYPARQTATLPDKRMTLWGKRSGQPGKSLQEGLLQQPSQHQMLESYATSCRLPASTDYSTLRVPHQPSWDLSAPQGCPVPPSSVKAPGPRRVDMPPEEDWRQNSYTPQPGRRWMLPVHVKDGTFSSASEAHRNMLARAAAATGTVQKNGW", "length": 1746, "header": "tr|A0A8V0ZBM3-1|A0A8V0ZBM3_CHICK Isoform 1 of Ubiquitin specific peptidase 54 OS=Gallus gallus OX=9031 GN=USP54 PE=3 SV=1 CANONICAL=A0A8V0ZBM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3/entry#A0A8V0ZBM3-1", "sequence": { "sequence": "MSWKRSYFSVGRGNVQGMFTPRSTTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRSFRQISTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDALRTALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAPHCVSHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPTPDMFGELLQNASTMGDLRNCPSNCGEKIRIRRVLMNSPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKHSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPRGTPVSTQDLPSQVDLQQYSRTCYDSEDSGREPSISSDTRTDSSTDSYPYKQAHHESVVSHFSSDSQGTVIYNVDNDAASQSSRDTGHLTDSECNQRHISKKSSLADRKRSSSRSRRKGDEAQSSGYHSEGETLKEKQAPRAAPKPSSSTSRLREFKETVSNMIHNRPQQISQTNQNAPHGGSHMDQAETRPSKSLSVHSRDWEVESTSSESKSSSSSRYRPSWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEEAGKELMENEVKEHTVQETRSSQSNVRYKRPVLSRGTQHVMDQHPHLIQRMESGYESSERNSNSPVSLDIPLSESSSTHRDIHMKRTGGLVPAWRSIPKSHSSSILEVEPTSSNGSWANSPRTFGNGGEMFAPLKSELDELQEEVARRAHEQELRRKREKEMEAAMGFNPRPSRFMDLDELQNQGRSDGFEKSMQEADSIFEESLNQEQKGDCASALALCNEAISKLRLAMHDANSSTHSRALVDKKLQISIRKARSLQDRMQHQQPSQPLPSPTCHPPQGGTVSQSTSEQTGPFQVLLSQEVPLEPNKEVEFGSSSFFHPPASCHELHSSLYPESSSLSPPESNPSNRISPNFQSASSDFHDQVPSFPYRQGLAERSARTENDAHHSVEFTDTTAAGPKEYRECCSSSKLEEVHSIAPILTPQYKSKTNTVNSGSLPTLFPCPHPPQAASPEKDNQHSPCSKLSSSPVRPSIDHLGSYREMSPATSSPSQQCSLDPLQKTDKYSRANSHEILLPSQDEYGIAEGCKSEAFSTKGHVRSLAEQFQKMHAVSQRKGTHERGWISAVCQDETSPKQIQKSSFNPSPSDYRQLIHQNQENKTQSSEKLHSTVDIRDGVVSLEGKQVASKSICSISEELCRRGGQNIVDPAPYLERHCHDGGMKQVDDGASSSMVASMPVDRWVDNVTRYYSSQKDNKNTEWLPVPGRSPSLSDQRAVGDDLSRIPVHLHPQWNQDTEQELSELESLYQTSLQASQATRPFLGRQDSARYPFDHSVSANLNVRKLHTTAGMGLSKTPTAEIERSLYGSTVSSVSKVTYTREHSREPEEEEMYSAENFRRIARSLSGTVVSNREETLVSSHSFEAPNMRKMPMETSHRSSSSTSLPFPHDPPVFPFDPQHTPNQVQHLPHDVLVPSMVGKARKPSGDQKNIIQKLLVMPDRGEAFQGEDYPGMALSYGSLPCAPRGTLSQGQKPLPNLCSGGGASNVSGHWLNRSYPARQTATLPDKRMTLWGKRSGQPGKSLQEGLLQQPSQHQMLESYATSCRLPASTDYSTLRVPHQPSWDLSAPQGCPVPPSSVKAPGPRRVDMPPEEDWRQNSYTPQPGRRWMLPVHVKDGTFSSASEAHRNMLARAAAATGTVQKNGW", "length": 1746, "header": "tr|A0A8V0ZBM3-1|A0A8V0ZBM3_CHICK Isoform 1 of Ubiquitin specific peptidase 54 OS=Gallus gallus OX=9031 GN=USP54 PE=3 SV=1 CANONICAL=A0A8V0ZBM3-1" }, "locus": { "chromosome": "6", "start_pos": 16907673, "end_pos": 16858045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051486.1", "url": "https://www.ensembl.org/id/ENSGALT00010051486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030677.1", "url": "https://www.ensembl.org/id/ENSGALP00010030677.1" } ] } }, { "isoform_ac": "A0A8V0ZIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3/entry#A0A8V0ZIQ6-1", "sequence": { "sequence": "MDSFPFANFVAACKGGFCIHKHQMNTEGCKSEAFSTKGHVRSLAEQFQKMHAVSQRKGTHERGWISAVCQDETSPKQIQKSSFNPSPSDYRQLIHQNQENKTQSSEKLHSTVDIRDGVVSLEGKQVASKSICSISEELCRRGGQNIVDPAPYLERHCHDGGMKQVDDGASSSMVASMPVDRWVDNVTRYYSSQKDNKNTEWLPVPGRSPSLSDQRAVGDDLSRIPVHLHPQWNQDTEQELSELESLYQTSLQASQATRPFLGRQDSARYPFDHSVSANLNVRKLHTTAGMGLSKTPTAEIERSLYGSTVSSVSKVTYTREHSREPEEEEMYSAENFRRIARSLSGTVVSNREETLVSSHSFEAPNMRKMPMETSHRSSSSTSLPFPHDPPVFPFDPQHTPNQVQHLPHDVLVPSMVGKARKPSGDQKNIIQKLLVMPDRGEAFQGEDYPGMALSYGSLPCAPRGTLSQGQKPLPNLCSGGGASNVSGHWLNRSYPARQTATLPDKRMTLWGKRSGQPGKSLQEGLLQQPSQHQMLESYATSCRLPASTDYSTLRVPHQPSWDLSAPQGCPVPPSSVKAPGPRRVDMPPEEDWRQNSYTPQPGRRWMLPVHVKDGTFSSASEAHRNMLARAAAATGTVQKNGW", "length": 642, "header": "tr|A0A8V0ZIQ6-1|A0A8V0ZIQ6_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 54 OS=Gallus gallus OX=9031 GN=USP54 PE=4 SV=1 CANONICAL=A0A8V0ZBM3-1" }, "locus": { "chromosome": "6", "start_pos": 16907673, "end_pos": 16857778, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051484.1", "url": "https://www.ensembl.org/id/ENSGALT00010051484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030675.1", "url": "https://www.ensembl.org/id/ENSGALP00010030675.1" } ] } }, { "isoform_ac": "E1BU81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3/entry#E1BU81-1", "sequence": { "sequence": "MSWKRSYFSVGRGNVQGMFTPRSTTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRSFRQISTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDALRTALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAPHCVSHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPTPDMFGELLQNASTMGDLRNCPSNCGEKIRIRRVLMNSPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKHSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPRGTPVSTQDLPSQVDLQQYSRTCYDSEDSGREPSISSDTRTDSSTDSYPYKQAHHESVVSHFSSDSQGTVIYNVDNDAASQSSRDTGHLTDSECNQRHISKKSSLADRKRSSSRSRRKGDEAQSSGYHSEGETLKEKQAPRAAPKPSSSTSRLREFKETVSNMIHNRPQQISQTNQNAPHGGSHMDQAETRPSKSLSVHSRDWEVESTSSESKSSSSSRYRPSWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEEAGKELMENEVKEHTVQETRSSQSNVRYKRPVLSRGTQHVMDQHPHLIQRMESGYESSERNSNSPVSLDIPLSESSSTHRDIHMKRTGGLVPAWRSIPKSHSSSILEVEPTSSNGSWANSPRTFGNGGEMFAPLKSELDELQEEVARRAHEQELRRKREKEMEAAMGFNPRPSRFMDLDELQNQGRSDGFEKSMQEADSIFEESLNQEQKGDCASALALCNEAISKLRLAMHDANSSTHSRALVDKKLQISIRKARSLQDRMQHQQPSQPLPSPTCHPPQGGTVSQSTSEQTGPFQVLLSQEVPLEPNKEVEFGSSSFFHPPASCHELHSSLYPESSSLSPPESNPSNRISPNFQSASSDFHDQVPSFPYRQGLAERSARTENDAHHSVEFTDTTAAGPKEYRECCSSSKLEEVHSIAPILTPQYKSKTNTVNSGSLPTLFPCPHPPQAASPEKDNQHSPCSKLSSSPVRPSIDHLGSYREMSPATSSPSQQCSLDPLQKTDKYSRANSHEILLPSQDEYGIAEGCKSEAFSTKGHVRSLAEQFQKMHAVSQRKGTHERGWISAVCQDETSPKQIQKSSFNPSPSDYRQLIHQNQENKTQSSEKLHSTVDIRDGVVSLEGKQVASKSICSISEELCRRGGQNIVDPAPYLERHCHDGGMKQVDDGASSSMVASMPVDRWVDNVTRYYSSQKDNKNTEWLPVPGRSPSLSDQRAVGDDLSRIPVHLHPQWNQDTEQELSELESLYQTSLQASQATRPFLGRQDSARYPFDHSVSANLNVRKLHTTAGMGLSKTPTAEIERSLYGSTVSSVSKVTYTREHSREPEEEEMYSAENFRRIARSLSGTVVSNREETLVSSHSFEAPNMRKMPMETSHRSSSSTSLPFPHDPPVFPFDPQHTPNQVQHLPHDVLVPSMVGKARKPSGDQKNIIQKLLVMPDRGEAFQGEDYPGGGASNVSGHWLNRSYPARQTATLPDKRMTLWGKRSGQPGKSLQEGLLQQPSQHQMLESYATSCRLPASTDYSTLRVPHQPSWDLSAPQGCPVPPSSVKAPGPRRVDMPPEEDWRQNSYTPQPGRRWMLPVHVKDGTFSSASEAHRNMLARAAAATGTVQKNGW", "length": 1717, "header": "tr|E1BU81-1|A0A8V0ZBM3_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 54 OS=Gallus gallus OX=9031 GN=USP54 PE=3 SV=4 CANONICAL=A0A8V0ZBM3-1" }, "locus": { "chromosome": "6", "start_pos": 16907673, "end_pos": 16858045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051481.1", "url": "https://www.ensembl.org/id/ENSGALT00010051481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030672.1", "url": "https://www.ensembl.org/id/ENSGALP00010030672.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1289, "end_pos": 1291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1595, "end_pos": 1597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM3" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 352, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 205 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1289, "end_pos": 1291 }, { "start_pos": 1588, "end_pos": 1590 }, { "start_pos": 1595, "end_pos": 1597 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 842, "end_pos": 844 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBP3-1", "uniprot_ac": "A0A8V0ZBP3", "uniprot_id": "A0A8V0ZBP3_CHICK", "mass": { "chemical_mass": 78280.0, "monoisotopic_mass": 78280.0 }, "refseq": { "ac": "XP_015152604", "name": "segment polarity protein dishevelled homolog DVL-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152604" }, "gene_names": [ { "name": "DVL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ] }, { "name": "DVL1", "type": "synonym", "evidence": [ { "id": "XP_015152604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152604" } ] } ], "protein_names": [ { "name": "Dishevelled segment polarity protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3/entry#names_and_taxonomy" } ] }, { "name": "segment polarity protein dishevelled homolog DVL-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152604" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152604" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3", "locus": { "chromosome": "21", "start_pos": 2332882, "end_pos": 2267282, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018012", "url": "https://www.ensembl.org/id/ENSGALG00010018012" } ] } } ], "crossref": [ { "id": "A0A8V0ZBP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419416", "url": "https://www.ncbi.nlm.nih.gov/gene/419416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419416", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GTFPRYG", "url": "https://omabrowser.org/oma/group/GTFPRYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z476", "url": "https://www.orthodb.org/?gene=A0A8V0Z476", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Q0", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBM6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10878:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10878:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201688", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4641258", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641258", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4641262", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z476", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z476", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z476-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z476-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESSHSDTGSQCTESHADLPPPIERTGGIGDSRPPSFHPNAASSRDGLDNETGTESVISHRRDRHRRRNREGHEDVPRINGHPKLDRHREHPPGYDSSSTMMSSELESSSFIDSDDDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWISHTTAMTGAYPRYGMSPSMSITTSTSSSLTSSIPESEKLEESPLTVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKDRREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNMAALNLNNGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPLPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSNRSNSENSRRALGREKDRKSAGSGSESDHTACSGGTGTARRERPVSQLSHRSHVSATHSERSHHSHHSYGPPGVPPLYNLPKLGSKVYGTTSGPPGGPPVRELSSVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 712, "header": "tr|A0A8V0ZBP3-1|A0A8V0ZBP3_CHICK Isoform 1 of Dishevelled segment polarity protein 1 OS=Gallus gallus OX=9031 GN=DVL1 PE=1 SV=1 CANONICAL=A0A8V0ZBP3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z476-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3/entry#A0A8V0Z476-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESSHSDTGSQCTESHADLPPPIERTGGIGDSRPPSFHPNAASSRDGLDNETGTESVISHRRDRHRRRNREGHEDVPRINGHPKLDRHREHPPGYDSSSTMMSSELESSSFIDSDDDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWISHTTAMTGAYPRYELEESPLTVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKDRREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNMAALNLNNGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPLPPPCFPPAYQDPGFSYGSGSAGSQQSEGHLVMEIPKSSSEHHKDATEQTPSRLQKLLVYPQRDTLLLLQG", "length": 592, "header": "tr|A0A8V0Z476-1|A0A8V0Z476_CHICK Computationally mapped isoform of Dishevelled segment polarity protein 1 OS=Gallus gallus OX=9031 GN=DVL1 PE=1 SV=1 CANONICAL=A0A8V0ZBP3-1" }, "locus": { "chromosome": "21", "start_pos": 2331878, "end_pos": 2267460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043550.1", "url": "https://www.ensembl.org/id/ENSGALT00010043550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025902.1", "url": "https://www.ensembl.org/id/ENSGALP00010025902.1" } ] } }, { "isoform_ac": "A0A8V0Z4Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3/entry#A0A8V0Z4Q0-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESSHSDTGSQCTESHADLPPPIERTGGIGDSRPPSFHPNAASSRDGLDNETGTESVISHRRDRHRRRNREGHEDVPRINGHPKLDRHREHPPGYDSSSTMMSSELESSSFIDSDDDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWISHTTAMTGAYPRYELEESPLTVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKDRREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNMAALNLNNGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPLPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSNRSNSENSRRALGREKDRNHVSATHSERSHHSHHSYGPPGVPPLYNLPKLGSKVYGTTSGPPGGPPVRELSSVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 655, "header": "tr|A0A8V0Z4Q0-1|A0A8V0Z4Q0_CHICK Computationally mapped isoform of Dishevelled segment polarity protein 1 OS=Gallus gallus OX=9031 GN=DVL1 PE=1 SV=1 CANONICAL=A0A8V0ZBP3-1" }, "locus": { "chromosome": "21", "start_pos": 2321159, "end_pos": 2267460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043533.1", "url": "https://www.ensembl.org/id/ENSGALT00010043533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025889.1", "url": "https://www.ensembl.org/id/ENSGALP00010025889.1" } ] } }, { "isoform_ac": "A0A8V0ZBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3/entry#A0A8V0ZBM6-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESSHSDTGSQCTESHADLPPPIERTGGIGDSRPPSFHPNAASSRDGLDNETGTESVISHRRDRHRRRNREGHEDVPRINGHPKLDRHREHPPGYDSSSTMMSSELESSSFIDSDDDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWISHTTAMTGAYPRYGMSPSMSITTSTSSSLTSSIPESEKLEESPLTVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKDRREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNMAALNLNNGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPLPPPCFPPAYQDPGFSYGSGSAGSQQSEALD", "length": 576, "header": "tr|A0A8V0ZBM6-1|A0A8V0ZBP3_CHICK Computationally mapped isoform of Dishevelled segment polarity protein 1 OS=Gallus gallus OX=9031 GN=DVL1 PE=1 SV=1 CANONICAL=A0A8V0ZBP3-1" }, "locus": { "chromosome": "21", "start_pos": 2319223, "end_pos": 2267460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043523.1", "url": "https://www.ensembl.org/id/ENSGALT00010043523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025881.1", "url": "https://www.ensembl.org/id/ENSGALP00010025881.1" } ] } }, { "isoform_ac": "A0A8V0ZBP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3/entry#A0A8V0ZBP3-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLPVPPEKVTLADFKNVLSNRPVHSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAESSHSDTGSQCTESHADLPPPIERTGGIGDSRPPSFHPNAASSRDGLDNETGTESVISHRRDRHRRRNREGHEDVPRINGHPKLDRHREHPPGYDSSSTMMSSELESSSFIDSDDDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSKPGPISLTVAKCWDPTPRSYFTIPRAEPVRPIDPAAWISHTTAMTGAYPRYGMSPSMSITTSTSSSLTSSIPESEKLEESPLTVKSDMATIVKVMQLPDSGLEIRDRMWLKITISNAVIGADVVDWLYTHVEGFKDRREARKYASSMLKHGYLRHTVNKITFSEQCYYVFGDLCGNMAALNLNNGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPLPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSNRSNSENSRRALGREKDRKSAGSGSESDHTACSGGTGTARRERPVSQLSHRSHVSATHSERSHHSHHSYGPPGVPPLYNLPKLGSKVYGTTSGPPGGPPVRELSSVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 712, "header": "tr|A0A8V0ZBP3-1|A0A8V0ZBP3_CHICK Isoform 1 of Dishevelled segment polarity protein 1 OS=Gallus gallus OX=9031 GN=DVL1 PE=1 SV=1 CANONICAL=A0A8V0ZBP3-1" }, "locus": { "chromosome": "21", "start_pos": 2321159, "end_pos": 2267460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043543.1", "url": "https://www.ensembl.org/id/ENSGALT00010043543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025896.1", "url": "https://www.ensembl.org/id/ENSGALP00010025896.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419416", "resource": "KEGG Pathway" }, { "id": "R-GGA-201688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201688", "resource": "Reactome", "description": "WNT mediated activation of DVL" }, { "id": "R-GGA-4641258", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641258", "resource": "Reactome", "description": "Degradation of DVL" }, { "id": "R-GGA-4641262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641262", "resource": "Reactome", "description": "Disassembly of the destruction complex and recruitment of AXIN to the membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GPK9-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-1 isoform X1", "gene_name": "Dvl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGLWLFSPWLDLQCLVAGLLCFWWALCKCLMFHLVTMAAEVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNRDEASRTNGHPRGDRRRDLGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLIRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFRERREARKYASSMLKRGFLRHTVNKITFSEQCYYVFGDLCTNLASLNLNSGSSGASDQDTLAPLPHPSVPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSTRSSHRTPGREERRAAGAGGSGSESDHTAPSGSGSTGWWERPVSQLSHGSSPRSQASAVAPGLPPLHPLTKAYAVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 733 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1N6M9-1", "protein_name": "Dishevelled segment polarity protein 1", "gene_name": "DVL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSCPASTAVWSPGWFWLRVLTRMQGLRALMDTQTCPRLLSGQVASGTPGLPPSTRMWPAAAMGWITRLARSHWSATGGSEPDAGTVKRGIPWPGPVPAVPTAARTNGHPRGDRRRDLGLPPDSASTVLSSELESSSFIDSDEDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMGAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYAHLEGFRERREARKYASSMLKRGFLRHTVNKVTFSEQCYYVFGDLCSNLAALNLNSGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFGYGSGSAGSQQSEGSKSSGSTRSAGGSSRRALGREKESRSAGAGGSGSESDHTVPSGAGGSGWRERPPSQLSRGSSPRSQASAAAPGLPPLHPLTKAYSVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 647 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJE5-1", "protein_name": "Dishevelled segment polarity protein 1", "gene_name": "DVL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDGHADLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESVVSHRRERARRRNREEAARTNGHPRGDRRRDLGLPPDSASTVLSSELESSSFIDSDEDDNTSRLSSSTEQSTSSRLIRKHKRRRRKQRMRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPSPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMGAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHLEGFRERREARRYASSMLKRGFLRHTVNKVTFSEQCYYVFGDLCSNLAALNLNSGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSTRSAGGSSRRALGREKESRSAGAGGSGSESDHTAPSGAGGSGWRERPASQLSRGSSPRSQASAAAPGLPPLHPLTKAYSVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 700 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14640-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-1", "gene_name": "DVL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 695 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51141-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-1", "gene_name": "Dvl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNRDEAARTNGHPRGDRRRDLGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLVRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLASLNLNSGSSGASDQDTLAPLPHPSVPWPLGQGYPYQYPGPPPCFPPAYQDPGFSCGSGSAGSQQSEGSKSSGSTRSSHRTPGREERRATGAGGSGSESDHTVPSGSGSTGWWERPVSQLSRGSSPRSQASAVAPGLPPLHPLTKAYAVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 695 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVB9-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-1", "gene_name": "Dvl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNRDEAARTNGHPRGDRRRELGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLIRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLASLNLNSGSSGASDQDTLAPLPHPSVPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSTRSSHRTPGREERRATGAGGSGSESDHTVPSGSGSTGWWERPVSQLSRGSSPRSQASAVAPGLPPLHPLTKAYAVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "length": 695 }, "evidence": [ { "id": "A0A8V0ZBP3", "url": "https://omabrowser.org/oma/group/A0A8V0ZBP3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "neuronal dense core vesicle", "id": "GO:0098992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "Wnt signalosome", "id": "GO:1990909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "presynapse assembly", "id": "GO:0099054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "Wnt signaling pathway, planar cell polarity pathway", "id": "GO:0060071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060071", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "outflow tract morphogenesis", "id": "GO:0003151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "postsynapse organization", "id": "GO:0099173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP3" }, { 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"database": "Ensembl Transcript", "id": "ENSGALT00010048553.1", "url": "https://www.ensembl.org/id/ENSGALT00010048553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028644.1", "url": "https://www.ensembl.org/id/ENSGALP00010028644.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ3" }, { "id": "PF20517", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20517" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 127 transmembrane region", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 138, "start_aa": "Cys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBR0-1", "uniprot_ac": "A0A8V0ZBR0", "uniprot_id": "A0A8V0ZBR0_CHICK", "mass": { "chemical_mass": 34411.0, "monoisotopic_mass": 34411.0 }, "refseq": { "ac": "XP_015145533", "name": "transmembrane protein 169", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145533" }, "gene_names": [ { "name": "TMEM169", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0" } ] }, { "name": "TMEM169", "type": "synonym", "evidence": [ { "id": "XP_015145533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145533" } ] } ], "protein_names": [ { "name": "Transmembrane protein 169", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 169", "type": "synonym", "evidence": [ { "id": "XP_015145533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145533" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145533.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM169", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0", "locus": { "chromosome": "7", "start_pos": 23175093, "end_pos": 23189601, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021253", "url": "https://www.ensembl.org/id/ENSGALG00010021253" } ] } } ], "crossref": [ { "id": "A0A8V0ZBR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "424223", "url": "https://www.ncbi.nlm.nih.gov/gene/424223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424223", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFSEWWQ", "url": "https://omabrowser.org/oma/group/AFSEWWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31777", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31777", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31777:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31777:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEVLESGSGLEDTVQKESKSGSHSPRHGSVRRAVTTAVTFDGEATMDRRKKKKKESRPESVIVYRSENENKVEEEQADEEGGERSSEEGSKFLGQSVTDGVWNMPSDSRYVTLTGTITRGKKKGQMVDIHVTLTDKELQELAKSKEPPKESVPEKKKCDVGLDRGPHIVLWTIICLPIIFVVSFVVSFYYGTITWYNIFLVYNEERTFWHKITFCPFLIIFYPIIIMVVSFSLGLYSAVTQVSWSFGDWWHAVRDMEKGFCGWLCSKLGLEDCSPYSIVELLDSDNISGSLSGKSSAQGVDTSAV", "length": 307, "header": "tr|A0A8V0ZBR0-1|A0A8V0ZBR0_CHICK Isoform 1 of Transmembrane protein 169 OS=Gallus gallus OX=9031 GN=TMEM169 PE=4 SV=1 CANONICAL=A0A8V0ZBR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR0/entry#A0A8V0ZBR0-1", "sequence": { "sequence": "MPSEVLESGSGLEDTVQKESKSGSHSPRHGSVRRAVTTAVTFDGEATMDRRKKKKKESRPESVIVYRSENENKVEEEQADEEGGERSSEEGSKFLGQSVTDGVWNMPSDSRYVTLTGTITRGKKKGQMVDIHVTLTDKELQELAKSKEPPKESVPEKKKCDVGLDRGPHIVLWTIICLPIIFVVSFVVSFYYGTITWYNIFLVYNEERTFWHKITFCPFLIIFYPIIIMVVSFSLGLYSAVTQVSWSFGDWWHAVRDMEKGFCGWLCSKLGLEDCSPYSIVELLDSDNISGSLSGKSSAQGVDTSAV", "length": 307, "header": "tr|A0A8V0ZBR0-1|A0A8V0ZBR0_CHICK Isoform 1 of Transmembrane protein 169 OS=Gallus gallus OX=9031 GN=TMEM169 PE=4 SV=1 CANONICAL=A0A8V0ZBR0-1" }, "locus": { "chromosome": "7", "start_pos": 23179372, "end_pos": 23176370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051526.1", "url": "https://www.ensembl.org/id/ENSGALT00010051526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030717.1", "url": "https://www.ensembl.org/id/ENSGALP00010030717.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424223", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H3Z1-1", "protein_name": "Transmembrane protein 169", "gene_name": "Tmem169", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEESAPAESQGQPASPNHGSLRRAVAAALALDGESTMGRRKKKRKESRPESIIIYRSDNEKMDEEPEESEGGDRPKEEEGEDFLDYPIDDGMWNMPLDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKELSREAAPEGRRVCQVGADQGPHVVLWTLVCLPVVFVLSFVVSFYYGTITWYNIFLVYNEERTFWHKISYCPCLILLYPVLIMAMASSLGLYAAVVQLSWSWGAWWRAACDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISGNLSNKDPIQGVETSSV", "length": 297 }, "evidence": [ { "id": "A0A8V0ZBR0", "url": "https://omabrowser.org/oma/group/A0A8V0ZBR0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TBG9-1", "protein_name": "Transmembrane protein 169", "gene_name": "TMEM169", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEPALVEGQSQLPSPHHNSLRKAMAAALVLDGESTMGRRKKKKKESRPESIIIYRSESETLDEEPGESEGGDQPKEEEGDDFIDYPMDDGVWNVPVDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKASSRETTPGGRKACQLGADRGPHVVLWTLVCLPVVFLLSFVVSFYYGTITWYNIFLVYNEERTFWHKISCCPCLILCYPVLIMAMASSLGLYAAVVQLSWSWEAWWQAARDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISGNLSNKDATQEIETSAV", "length": 297 }, "evidence": [ { "id": "A0A8V0ZBR0", "url": "https://omabrowser.org/oma/group/A0A8V0ZBR0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BG50-1", "protein_name": "Transmembrane protein 169", "gene_name": "Tmem169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEESAPVESQGQLPSPHHGSLRRAVAAVLALDGESTLGRRKKRRKDSRPESIIIYRSDNEKTDEEPEESEGGDRPKEEEGEDFLDYPGDDGVWNMPLDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKELSREAAPEGRRACQVGADQGPHVVLWTLVCLPVVFVLSFVVSFYYGTITWYNIFLVYNEERTFWHKISCCPCLILFYPVLIMTMASSLGLYAAVAQLSWSWAAWWRAACDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISGNLSNKDPIQEVETSTV", "length": 297 }, "evidence": [ { "id": "A0A8V0ZBR0", "url": "https://omabrowser.org/oma/group/A0A8V0ZBR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HH4-1", "protein_name": "Transmembrane protein 169", "gene_name": "TMEM169", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEPTAVEGQVQLPSPHQGSLRKAVAAALALDGESTMGHRKKKRKESRPESIIIYRSDNEKTDEEPGESEGGDQPKEEEGDDFLDYPVDDDMWNLPLDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKESSRETTPEGRMACQMGADRGPHVVLWTLICLPVVFILSFVVSFYYGTITWYNIFLVYNEERTFWHKISYCPCLVLFYPVLIMAMASSLGLYAAVVQLSWSWEAWWQAARDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISSTLSNKDPIQEVETSTV", "length": 297 }, "evidence": [ { "id": "A0A8V0ZBR0", "url": "https://omabrowser.org/oma/group/A0A8V0ZBR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCE8-1", "uniprot_ac": "A0A8V0ZCE8", "uniprot_id": "A0A8V0ZCE8_CHICK", "mass": { "chemical_mass": 162431.0, "monoisotopic_mass": 162431.0 }, "refseq": { "ac": "XP_040557472", "name": "pleckstrin homology domain-containing family H member 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557472" }, "gene_names": [ { "name": "PLEKHH1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" } ] }, { "name": "PLEKHH1", "type": "synonym", "evidence": [ { "id": "XP_040557472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557472" } ] } ], "protein_names": [ { "name": "Pleckstrin homology, MyTH4 and FERM domain containing H1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family H member 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040557472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8", "locus": { "chromosome": "5", "start_pos": 28371192, "end_pos": 28319337, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019875", "url": "https://www.ensembl.org/id/ENSGALG00010019875" } ] } } ], "crossref": [ { "id": "cd13206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13282", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13282", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17178", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17178", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423270", "url": "https://www.ncbi.nlm.nih.gov/gene/423270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELTEENGSCTDWQKRCLALESQLFKFRLQASKIRELLAEKMQELEQRVIEAEQRAEDAEKQVRVMGEEIKLANMKTSESNSTLYRKYQELMGTVQRKEDMISRLETQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELELENYHLKNCNQRLTEQIEALQDTLQDMTSIPPLESLWSCNSMKPRVPQTSYHEKTDQKSRLLAPAFRQVCQTGSTKRLLSTTNIVLANGNFTEDGEDRSLLSQNTLKILTDSPNWNLSTEKDMFPDISSEHRLRCSDPMSLDTPAEPTKLHGALTFQSSLEGNHSTVSTLERVTLDRASFPDDLAATFHSHCLDSSFSGEIMSIFEGRLQTAEPPRVVSASAVTACSICPEREYGLGTSMAFPKIRTPSTPRDSIQLAKRHYSQPQSGTSSSCHVMSFEASNFQPIKDSPVCHRPVEETDIDDDAVLEKMETEGGVVREEAGMCEINHLPTEQREFSSSKTGILEPGGKPPTPPLHRFPSWESRIYAVAKSGMRLSEVATVNDASSCSSGPFTCLIYRNTTVPVYTTLKGKATQISNVPFLDESSGSDDDCGSHASFRNSAAGSENRKTSMPGSPRAAKRGVSMSSVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTDGGICTEPMEKSGYLLKMGSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQIVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSILRVQVTSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRESKVEEVDRSCDSDEDYETTGGGLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLTVAAGSRNATVGTSYEQLIGKLLDAEGDPNSPLWKHPMLCYSKDGLHMSLTTLPSEALQTEALKLFKSCQLFINVPVEASSIDYHVSLAQTALQVCLTHTELQNEIFCQLVKQTNCRQPQNHSVIQCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPRSEIGKYAIYCQRSVDRTVQAGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEFIQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYEGGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSSEIASGRFPVNKELALEMVALMAQVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPEQLKQLADKLATKWMVLQGCSPPECVRIYLTVARKWPLFGTKLFAAKPVLPSSLEDCPVWIAVNEDGISILDYNTMHLKFSYSYSSVLTFGGCRDDFMIVVSQIKERSSGKNSTEKLLFTMAIPKIVEATLLIATYINSRSTTSLLPSTQPSRSTAPANRLWETESRCFFASMPRSTKGPTLL", "length": 1442, "header": "tr|A0A8V0ZCE8-1|A0A8V0ZCE8_CHICK Isoform 1 of Pleckstrin homology, MyTH4 and FERM domain containing H1 OS=Gallus gallus OX=9031 GN=PLEKHH1 PE=4 SV=1 CANONICAL=A0A8V0ZCE8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8/entry#A0A8V0ZBR7-1", "sequence": { "sequence": "MQELEQRVIEAEQRAEDAEKQVRVMGEEIKLANMKTSESNSTLYRKYQELMGTVQRKEDMISRLETQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELELENYHLKNCNQRLTEQIEALQDTLQDMTSIPPLESLWSCNSMKPRVPQTSYHEKTDQKSRLLAPAFRQVCQTGSTKRLLSTTNIVLANGNFTEDGEDRSLLSQNTLKILTDSPNWNLSTEKDMFPDISSEHRLRCSDPMSLDTPAEPTKLHGALTFQSSLEGNHSTVSTLERVTLDRASFPDDLAATFHSHCLDSSFSGEIMSIFEGRLQTAEPPRVVSASAVTACSICPEREYGLGTSMAFPKIRTPSTPRDSIQLAKRHYSQPQSGTSSSCHVMSFEASNFQPIKDSPVCHRPVEETDIDDDAVLEKMETEGGVVREEAGMCEINHLPTEQREFSSSKTGILEPGGKPPTPPLHRFPSWESRIYAVAKSGMRLSEVATVNDASSCFPNFSYSASGPFTCLIYRNTTVPVYTTLKGKATQISNVPFLDESSGSDDDCGSHASFRNSAAGSENRKTSMPGSPRAAKRGVSMSSVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTDGGICTEPMEKSGYLLKMGSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQIVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSILRVQVTSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRESKVEEVDRSCDSDEDYETTGGGLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLTVAAGSRNATVGTSYEQLIGKLLDAEGDPNSPLWKHPMLCYSKDGLHMSLTTLPSEALQTEALKLFKSCQLFINVPVEASSIDYHVSLAQTALQVCLTHTELQNEIFCQLVKQTNCRQPQNHSVIQCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPRSEIGKYAIYCQRSVDRTVQAGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEFIQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYEGGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSSEIASGRFPVNKELALEMVALMAQVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPEQLKQLADKLATKWMVLQGCSPPECVRIYLTVARKWPLFGTKLFAAKPVLPSSLEDCPVWIAVNEDGISILDYNTMHLKFSYSYSSVLTFGGCRDDFMIVVSQIKERSSGKNSTEKLLFTMAIPK", "length": 1349, "header": "tr|A0A8V0ZBR7-1|A0A8V0ZCE8_CHICK Computationally mapped isoform of Pleckstrin homology, MyTH4 and FERM domain containing H1 OS=Gallus gallus OX=9031 GN=PLEKHH1 PE=4 SV=1 CANONICAL=A0A8V0ZCE8-1" }, "locus": { "chromosome": "5", "start_pos": 28367790, "end_pos": 28332440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048037.1", "url": "https://www.ensembl.org/id/ENSGALT00010048037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028354.1", "url": "https://www.ensembl.org/id/ENSGALP00010028354.1" } ] } }, { "isoform_ac": "A0A8V0ZCE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8/entry#A0A8V0ZCE8-1", "sequence": { "sequence": "MAELTEENGSCTDWQKRCLALESQLFKFRLQASKIRELLAEKMQELEQRVIEAEQRAEDAEKQVRVMGEEIKLANMKTSESNSTLYRKYQELMGTVQRKEDMISRLETQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELELENYHLKNCNQRLTEQIEALQDTLQDMTSIPPLESLWSCNSMKPRVPQTSYHEKTDQKSRLLAPAFRQVCQTGSTKRLLSTTNIVLANGNFTEDGEDRSLLSQNTLKILTDSPNWNLSTEKDMFPDISSEHRLRCSDPMSLDTPAEPTKLHGALTFQSSLEGNHSTVSTLERVTLDRASFPDDLAATFHSHCLDSSFSGEIMSIFEGRLQTAEPPRVVSASAVTACSICPEREYGLGTSMAFPKIRTPSTPRDSIQLAKRHYSQPQSGTSSSCHVMSFEASNFQPIKDSPVCHRPVEETDIDDDAVLEKMETEGGVVREEAGMCEINHLPTEQREFSSSKTGILEPGGKPPTPPLHRFPSWESRIYAVAKSGMRLSEVATVNDASSCSSGPFTCLIYRNTTVPVYTTLKGKATQISNVPFLDESSGSDDDCGSHASFRNSAAGSENRKTSMPGSPRAAKRGVSMSSVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTDGGICTEPMEKSGYLLKMGSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQIVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSILRVQVTSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRESKVEEVDRSCDSDEDYETTGGGLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLTVAAGSRNATVGTSYEQLIGKLLDAEGDPNSPLWKHPMLCYSKDGLHMSLTTLPSEALQTEALKLFKSCQLFINVPVEASSIDYHVSLAQTALQVCLTHTELQNEIFCQLVKQTNCRQPQNHSVIQCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPRSEIGKYAIYCQRSVDRTVQAGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEFIQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYEGGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSSEIASGRFPVNKELALEMVALMAQVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPEQLKQLADKLATKWMVLQGCSPPECVRIYLTVARKWPLFGTKLFAAKPVLPSSLEDCPVWIAVNEDGISILDYNTMHLKFSYSYSSVLTFGGCRDDFMIVVSQIKERSSGKNSTEKLLFTMAIPKIVEATLLIATYINSRSTTSLLPSTQPSRSTAPANRLWETESRCFFASMPRSTKGPTLL", "length": 1442, "header": "tr|A0A8V0ZCE8-1|A0A8V0ZCE8_CHICK Isoform 1 of Pleckstrin homology, MyTH4 and FERM domain containing H1 OS=Gallus gallus OX=9031 GN=PLEKHH1 PE=4 SV=1 CANONICAL=A0A8V0ZCE8-1" }, "locus": { "chromosome": "5", "start_pos": 28368292, "end_pos": 28326813, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048045.1", "url": "https://www.ensembl.org/id/ENSGALT00010048045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028358.1", "url": "https://www.ensembl.org/id/ENSGALP00010028358.1" } ] } }, { "isoform_ac": "A0A8V0ZIC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8/entry#A0A8V0ZIC6-1", "sequence": { "sequence": "MKTSESNSTLYRKYQELMGTVQRKEDMISRLETQLAKQKQLRTEEAKIIQEKAAKIKEWVTFKLKELELENYHLKNCNQRLTEQIEALQDTLQDMTSIPPLESLWSCNSMKPRVPQTSYHEKTDQKSRLLAPAFRQVCQTGSTKRLLSTTNIVLANGNFTEDGEDRSLLSQNTLKILTDSPNWNLSTEKDMFPDISSEHRLRCSDPMSLDTPAEPTKLHGALTFQSSLEGNHSTVSTLERVTLDRASFPDDLAATFHSHCLDSSFSGEIMSIFEGRLQTAEPPRVVSASAVTACSICPEREYGLGTSMAFPKIRTPSTPRDSIQLAKRHYSQPQSGTSSSCHVMSFEASNFQPIKDSPVCHRPVEETDIDDDAVLEKMETEGGVVREEAGMCEINHLPTEQREFSSSKTGILEPGGKPPTPPLHRFPSWESRIYAVAKSGMRLSEVATVNDASSCFPNFSYSASGPFTCLIYRNTTVPVYTTLKGKATQISNVPFLDESSGSDDDCGSHASFRNSAAGSENRKTSMPGSPRAAKRGVSMSSVSSESDYAVPPDAYSLDGDYSEPEHKLQRTSSYSTDGGICTEPMEKSGYLLKMGSQVKMWKRRWFVLRNRQIMYYKSPSDVIRKPQGQMELNSSCQIVRGEGSQTFQLMTEKRTYFLTADSPNILEEWIHVLQSILRVQVTSPVGVPHSDAKPTVKGWLTKVKHGHSKLVWCALIGKTFYYYRNHEDKCPLGHLPMRESKVEEVDRSCDSDEDYETTGGGLLSSHCTLVIHPQDQSPTYLLIRTKQEKNTWLYHLTVAAGSRNATVGTSYEQLIGKLLDAEGDPNSPLWKHPMLCYSKDGLHMSLTTLPSEALQTEALKLFKSCQLFINVPVEASSIDYHVSLAQTALQVCLTHTELQNEIFCQLVKQTNCRQPQNHSVIQCWQLLALCAPLFLPQHHFLWYVKQHLQRHADPRSEIGKYAIYCQRSVDRTVQAGEREAKPSRMEIVSILLRNPYHHSLPFSIPVHFMNGTYQVVGFDGSSTVDEFIQRLNQETGMRKPSHMGFSLFTDDPSGRDLEHCLQGNMKICDVISKWEQALKELHPGKYEGGTRIVKLTYKNRLYFRSQAKGETDRERLLLAFQVSSEIASGRFPVNKELALEMVALMAQVEYGDLDRTASSSPGGTSHSKMQHLLHQVLDKFYPKRYKKNIAPEQLKQLADKLATKWMVLQGCSPPECVRIYLTVARKWPLFGTKLFAAKPVLPSSLEDCPVWIAVNEDGISILDYNTMHLKFSYSYSSVLTFGGCRDDFMIVVSQIKERSSGKNSTEKLLFTMAIPKIVEATLLIATYINSRSTTSLLPSTQPSRSTAPANRLWETESRCFFASMPRSTKGPTLL", "length": 1374, "header": "tr|A0A8V0ZIC6-1|A0A8V0ZIC6_CHICK Computationally mapped isoform of Pleckstrin homology, MyTH4 and FERM domain containing H1 OS=Gallus gallus OX=9031 GN=PLEKHH1 PE=4 SV=1 CANONICAL=A0A8V0ZCE8-1" }, "locus": { "chromosome": "5", "start_pos": 28368292, "end_pos": 28335280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048020.1", "url": "https://www.ensembl.org/id/ENSGALT00010048020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028346.1", "url": "https://www.ensembl.org/id/ENSGALP00010028346.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 495, "start_aa": "Thr", "end_pos": 495, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr495", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1371, "end_pos": 1373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 1070, "end_pos": 1407, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" }, { "id": "PS51016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MyTH4", "eco_id": "ECO_0000259", "start_pos": 905, "end_pos": 1059, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 652, "end_pos": 746, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 495 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1078, "end_pos": 1080 }, { "start_pos": 1371, "end_pos": 1373 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 701, "end_pos": 703 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 872, "end_pos": 874 }, { "start_pos": 8, "end_pos": 10 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBS1-1", "uniprot_ac": "A0A8V0ZBS1", "uniprot_id": "A0A8V0ZBS1_CHICK", "mass": { "chemical_mass": 161048.0, "monoisotopic_mass": 161048.0 }, "refseq": { "ac": "XP_004941683", "name": "RNA polymerase II-associated protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941683" }, "gene_names": [ { "name": "RPAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" } ] }, { "name": "RPAP1", "type": "synonym", "evidence": [ { "id": "XP_004941683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941683" } ] } ], "protein_names": [ { "name": "RNA polymerase II associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004941683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941683" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941683.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941683" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1", "locus": { "chromosome": "5", "start_pos": 24373224, "end_pos": 24408486, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020108", "url": "https://www.ensembl.org/id/ENSGALG00010020108" } ] } } ], "crossref": [ { "id": "423217", "url": "https://www.ncbi.nlm.nih.gov/gene/423217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423217", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYFLQCV", "url": "https://omabrowser.org/oma/group/KYFLQCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBS1", "url": "https://www.orthodb.org/?gene=A0A8V0ZBS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD71", "url": "https://www.orthodb.org/?gene=A0A8V0ZD71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21483:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21483:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941683", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFSRPKPGESEADLIHFQNQFLAARASPAVKIVKKADKRKGEERSTDAERPQLQDSKDVVMLDDFPDVLPALTPGPPKKSKIKSACVHFSDEDPEERLENHDQHITAVFSKIIERDTSAEAVTMPVPTGDPFPRIFHRSEIKSEVKVGSGRKSIFAQKMAARRAAEKPATAPSAECTQIASAPLDILNPEGSAEEVPRSSNRDNKADDIFTSQRPCIITGEGLGSQKSEQEAQAIHKENLEKLQSMSQEEILKEQERLLAQLDPSLVAFLKSRRSGNVDQKNEIKMEQNRPEEFVESLTVPQCAVGMSLSMQESGLEESVRRDESTKMEITDDDLPVKPRKEWIHMDNVEFEKLEWMKDLPPPRQKKTKKGMQARFSLKGDLIPADADLPTHLGLHHHGEEAERAGYSLQELFHLSRSQLIQQRTLALQVLGRIVQKARAGEFASSLKGSVLRLLLDAGFLFLLRFSLDDAVDNVMAASVGALRALLVSSDDEKYLDWTFSWYQGMAAFPFVPNNEEEEEEEEEEEEELTGAEKSQNKKQTDENKPDADVARYDAVKGLLKTRIQHRLRYILEVVRPVPTVVLDILHILTHIARHSSEACIQLLDCPRLIDTIVREFLPTRWDPHVAEPGCLLTSLHGVACAAAMKFIRVLASGGRNATARLLNKFEMKSRLIRFTAEDPQDLLLPREEAIRLSTEAFRLWAVAAGYGQACDLYRDLYPVLVRILQSLPELLSTSHEKNPMFELSVQRAAAVVTLLVHVTQTAGYAVELHAKLSSCEDGEQIPPPPITWNQVSGLQPFLETSMKKFLQVISWTETWQILQPLTTTYMIYLGVYYSACSQQPSVNPVDFLEELERLTSEVLQPLLSQPAMHSMWDLLRPCSALCNPLSCSPAPESVFSIVSLSCTGGKPPLSLVGSKSPFPFLTALLFLIDSITHIHKGLISKYSSVLSIEGLKDYLHQSWQTAPPSVTPASAWMLRHEYHLQYFALVLARKMAGTCPDYSRHASLHHCVAMALLSRLLPGSEHLAYEILLDLAFNPEFLPEGKTGGPEAADFSDILHLGTSAKLSQPGSAAVSSSKPTRGALLRESYQNLPAIRSCYLSHFVHLQPALVRSQASYQGRNYLIQSMLLPEVRGPILPSDWPFFPLISLYNKVTNAETRGAVLNSLPLDLVNTVTWNLQWVLLLESWRPKTLQSIPIAAKLARLMCIFLTGGDLFLEAPIHCYTAALLSVYCQPKALDSLNLDAPLPGLASFHDLYISLLEQFEGVSFGDPLFGVFVLLPLQKRFSVHLRLSVFGEHTSILRALGVPLQQFPVPLERYTSPPEDNLNLLRHYFRTLVTGALRNTWCPVLYVVAVAHVNSFIFSQDSTTQEADAARKSMLRKTWLLVDETLKKHLLYYRLLNAESPLGFDLYEQLPPIRLKYLQMVTQKENKENAPVLVS", "length": 1438, "header": "tr|A0A8V0ZBS1-1|A0A8V0ZBS1_CHICK Isoform 1 of RNA polymerase II associated protein 1 OS=Gallus gallus OX=9031 GN=RPAP1 PE=1 SV=1 CANONICAL=A0A8V0ZBS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1/entry#A0A8V0ZBS1-1", "sequence": { "sequence": "MMFSRPKPGESEADLIHFQNQFLAARASPAVKIVKKADKRKGEERSTDAERPQLQDSKDVVMLDDFPDVLPALTPGPPKKSKIKSACVHFSDEDPEERLENHDQHITAVFSKIIERDTSAEAVTMPVPTGDPFPRIFHRSEIKSEVKVGSGRKSIFAQKMAARRAAEKPATAPSAECTQIASAPLDILNPEGSAEEVPRSSNRDNKADDIFTSQRPCIITGEGLGSQKSEQEAQAIHKENLEKLQSMSQEEILKEQERLLAQLDPSLVAFLKSRRSGNVDQKNEIKMEQNRPEEFVESLTVPQCAVGMSLSMQESGLEESVRRDESTKMEITDDDLPVKPRKEWIHMDNVEFEKLEWMKDLPPPRQKKTKKGMQARFSLKGDLIPADADLPTHLGLHHHGEEAERAGYSLQELFHLSRSQLIQQRTLALQVLGRIVQKARAGEFASSLKGSVLRLLLDAGFLFLLRFSLDDAVDNVMAASVGALRALLVSSDDEKYLDWTFSWYQGMAAFPFVPNNEEEEEEEEEEEEELTGAEKSQNKKQTDENKPDADVARYDAVKGLLKTRIQHRLRYILEVVRPVPTVVLDILHILTHIARHSSEACIQLLDCPRLIDTIVREFLPTRWDPHVAEPGCLLTSLHGVACAAAMKFIRVLASGGRNATARLLNKFEMKSRLIRFTAEDPQDLLLPREEAIRLSTEAFRLWAVAAGYGQACDLYRDLYPVLVRILQSLPELLSTSHEKNPMFELSVQRAAAVVTLLVHVTQTAGYAVELHAKLSSCEDGEQIPPPPITWNQVSGLQPFLETSMKKFLQVISWTETWQILQPLTTTYMIYLGVYYSACSQQPSVNPVDFLEELERLTSEVLQPLLSQPAMHSMWDLLRPCSALCNPLSCSPAPESVFSIVSLSCTGGKPPLSLVGSKSPFPFLTALLFLIDSITHIHKGLISKYSSVLSIEGLKDYLHQSWQTAPPSVTPASAWMLRHEYHLQYFALVLARKMAGTCPDYSRHASLHHCVAMALLSRLLPGSEHLAYEILLDLAFNPEFLPEGKTGGPEAADFSDILHLGTSAKLSQPGSAAVSSSKPTRGALLRESYQNLPAIRSCYLSHFVHLQPALVRSQASYQGRNYLIQSMLLPEVRGPILPSDWPFFPLISLYNKVTNAETRGAVLNSLPLDLVNTVTWNLQWVLLLESWRPKTLQSIPIAAKLARLMCIFLTGGDLFLEAPIHCYTAALLSVYCQPKALDSLNLDAPLPGLASFHDLYISLLEQFEGVSFGDPLFGVFVLLPLQKRFSVHLRLSVFGEHTSILRALGVPLQQFPVPLERYTSPPEDNLNLLRHYFRTLVTGALRNTWCPVLYVVAVAHVNSFIFSQDSTTQEADAARKSMLRKTWLLVDETLKKHLLYYRLLNAESPLGFDLYEQLPPIRLKYLQMVTQKENKENAPVLVS", "length": 1438, "header": "tr|A0A8V0ZBS1-1|A0A8V0ZBS1_CHICK Isoform 1 of RNA polymerase II associated protein 1 OS=Gallus gallus OX=9031 GN=RPAP1 PE=1 SV=1 CANONICAL=A0A8V0ZBS1-1" }, "locus": { "chromosome": "5", "start_pos": 24406419, "end_pos": 24373706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048572.1", "url": "https://www.ensembl.org/id/ENSGALT00010048572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028664.1", "url": "https://www.ensembl.org/id/ENSGALP00010028664.1" } ] } }, { "isoform_ac": "A0A8V0ZD71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1/entry#A0A8V0ZD71-1", "sequence": { "sequence": "MMFSRPKPGESEADLIHFQNQFLAARASPAVKIVKKADKRKGEERSTDAERPQLQDSKDVVMLDDFPDVLPALTPGPPKKSKIKSACVHFSDEDPEERLENHDQHITAVFSKIIERDTSAEAVTMPVPTGDPFPRIFHRSEIKSEVKVGSGRKSIFAQKMAARRAAEKPATAPSAECTQIASAPLDILNPEGSAEEVPRSSNRDNKADDIFTSQRPCIITGEGLGSQKSEQEAQAIHKENLEKLQSMSQEEILKEQERLLAQLDPSLVAFLKSRRSGNVDQKNEIKMEQNRPEEFVESLTVPQCAVGMSLSMQESGLEESVRRDESTKMEITDDDLPVKPRKEWIHMDNVEFEKLEWMKDLPPPRQKKTKKGMQARFSLKGDLIPADADLPTHLGLHHHGEEAERAGYSLQELFHLSRSQLIQQRTLALQVLGRIVQKARAGEFASSLKGSVLRLLLDAGFLFLLRFSLDDAVDNVMAASVGALRALLVSSDDEKYLDWTFSWYQGMAAFPFVPNNEEEEEEEEEEEEELTGAEKSQNKKQTDENKPDADVARYDAVKGLLKTRIQHRLRYILEVVRPVPTVVLDILHILTHIARHSSEACIQLLDCPRLIDTIVREFLPTRWDPHVAEPGCLLTSLHGVACAAAMKFIRVLASGGRNATARLLNKFEMKSRLIRFTAEDPQDLLLPREEAIRLSTEAFRLWAVAAGYGQACDLYRDLYPVLVRILQSLPELLSTSHEKNPMFELSVQRAAAVVTLLVHVTQTAGYAVELHAKLSSCEDGEQIPPPPITWNQVSGLQPFLETSMKKFLQVISWTETWQILQPLTTTYMIYLGVYYSACSQQPSVNPVDFLEELERLTSEVLQPLLSQPAMHSMWDLLRPCSALCNPLSCSPAPESVFSIVSLSCTGGKPPLSLVGSKSPFPFLTALLFLIDSITHIHKGLISKYSSVLSIEGLKDYLHQSWQTAPPSVTPASAWMLRHEYHLQYFALVLARKMAGTCPDYSRHASLHHCVAMALLSRLLPGSEHLAYEILLDLAFNPEFLPEGKTGGPEAADFSDILHLGTSAKLSQPGSAAVSSSKPTRGALLRESYQNLPAIRSCYLSHFVHLQPALVRSQASYQGRNYLIQSMLLPEVRGPILPSDWPFFPLISLYNKVTNAETRGAVLNSLPLDLVNTVTWNLQWVLLLESWRPKTLQSIPIAAKLARLMCIFLTGGDLFLEAPIHCYTAALLSVYCQPKALDSLNLDAPLPGLASFHDLYISLLEQFEGVSFGDPLFGVFVLLPLQKRFSVHLRLSVFGEHTSILRALGVPLQQFPVPLERYTSPPEDNLNLLRHYFRTLVTGALRNTWCPVLYVVAVAHVNSFIFSQDSTTQVGKECQCFRAGSFGFCT", "length": 1385, "header": "tr|A0A8V0ZD71-1|A0A8V0ZD71_CHICK Computationally mapped isoform of RNA polymerase II associated protein 1 OS=Gallus gallus OX=9031 GN=RPAP1 PE=1 SV=1 CANONICAL=A0A8V0ZBS1-1" }, "locus": { "chromosome": "5", "start_pos": 24406419, "end_pos": 24375379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048569.1", "url": "https://www.ensembl.org/id/ENSGALT00010048569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028660.1", "url": "https://www.ensembl.org/id/ENSGALP00010028660.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 969, "start_aa": "Thr", "end_pos": 969, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr969", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423217", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M294-1", "protein_name": "RNA polymerase II-associated protein 1 isoform X1", "gene_name": "Rpap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAHPDQLPLQDRRDVVMLDNLPDLPPALVPAPAKKARPSPGHSLPHDEDPEERLSRHDQHITAVLSKIIERDTSSVTVTLPVPSGVAFPPVFHRSQERQGKSAAPGKRSIFAQEIAARRVTEDRVSAARGAVPSLDPPEGAVLSETPSSRDKGSQFPGGSHDFHRSNLVTGKGLRSQAAEQEVQTIHEENVARLQAMDPKEILKEQQQLLAQLDPSLVAFLRSHSHALEQAGTKATKEQSPGRPTVPVTTEESVVSASTSEPRTEEKLEPKAPALKLPVTPHKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSQIISRAQAGEFGDRLVGSILRLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRTLLVAPGDEELLDSTFSWYHGALVFPLMPSQENKDDEDEDEEPTTRKAKKTPEEESRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVVLDILAVLIRLARHSLESATRVLECPRLIETIVQEFLPTNWSPVGVGPTSSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDFRSRLCRFIAEAPQELALPPEEAETLSTEAFRLWAVVASYGQGGDLYRELYPVLMRALQTLPTELSTHPPQPLSMQRMASLLTLLTQLTLAASSAHPEPTSGSAEACVSAIPSSITWTQVSGLQPLVEPCLKQILKFLPRPDVWSALGPVPSACLLFLGAYYQAWSQQSGLCPEDWLQDVERLLDEFLLPLLSQSSLDYLWDSLRHCSPLCNPLSCAPAPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLFNILLRIHKGLCGQLAAVLAAPGLQQYFLQCVTPMPAPQLTPFSAWALHHEYHLQYLVLSLAQKVATLKPELAANTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPENATGGPEAADFSDGLSLGNSGDPQCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELLRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGTAVRVLQWALVLESWRPEALCAVPPAARLARLMCVFLVDSELFRETPIQHLVAALLARLCRPQVLPSLNLDCPLPGLASFPDLYASFLEHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLALLQLYFRALVTGALRPHWCPVLYTVAVAHVNSFIFSQDPKSPDEVKAARKNMLQKTWLLADEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQHLQTLPTEGLQNGGSKT", "length": 1392 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0JN53-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "RPAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSRPKPGESEVDLLRFQSQFLAAGATPAVQLVKKGSRRAGDANLEQPPLQDHRDVVMLDSLPDLPPALVPAPPKRARPSPGHLLPEHEDPEERLHRHDQHITAVLTKIIERDTSSMPVNLPVSSGVAFPPVFHRSQGRQGKPVTAGKRSIFAQEIAARRASGAKVSPVREVESILDPPESAMTCEALTPREWGSQPPWNSYSFQGPHLVTGKGLKGQEAEQEAQTIHEENVARLQALAPEEILQEQQRLLAQLDPSLVAFLKSHSCTREQAEEKATREQRPGRPSAEVIGKEAIAPTSASVPRQENELEPETPALALPVTPQKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDMDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLAQVIGRAQAGEFGDRLVGSVLHLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRALLVAPGDEELLDSTFSWYHGALMFALMPSQEDKEDEDEDEEPPAEKAKTKSPEEGNRPPSDLARHDIIKGLLATNLLPRLRYVLEVTCPGPSVVLDILTVLIRLARHSLESATRVLECPRLVETVVREFLPTSWSPMGSGPTSSLHRVPCAPAMKLLRVLASASRNIAARLLSGFDLRSRLSRFIAEDPQDLALPLEEAETLSTEAFRLWAVAASYGLGSDLYRELYPVLMQALQDVPKELSSPPPRPLAVQRIASLLTLLTQLTLAAGHIAPEHNSHSAEASLLAGSSSVTWTQVSGLQPLVEPCLRQTLKLLPRPEMWSALGPVPTACLLFLDAYYQAWSQQPGLCPEDWLQDMERLSEGLLLPLLKHPSLGSLWDSLGCCSPLCNPQSCAVAPETISSLASLGCAGGHPPLSLAGSASPFPFLTALLSLLNTLGRIHKGLCGQLATVLAAPGLQDYFLRCVAPVAALHLTPFSAWALRHEYHLQYLALTLAQRAATLQPPMSGTDAALCHGMALALLGRLLPGSEHLAHELMLSCVFRLEFLPERASGGPEAADFSDRLSLGSGGDLGCGRGALLAQACQDLPSIRSCYLTHCSLARASLLASQALYRGELQRVPALLLPVPKEPLLPTDWPFLPLIQLYHRASDTPSGLPPADTVGTALRALQWVLVLESWRPRALWAVSPAARLARLMCVFLVDSELFRETPIQRLVAALLARLCQPEVLSNLNLDCPLPGLTSFPDLYANFLEHFEAVSFGDHLFGALILLPLQRRFSVTLRLALFGEHVGALRALGLPLTQLPVSLECYTAPPEDNLALLQLYFRALVTGALRPRWCPVLYAVAVAHVNSFIFSQDPNNSDEIKAACRSMLQKTWLLTDEGLRQHLLHYKLPNSALPEGFELYPQLPPLRQQYLQKLRISGVLPNGVSDT", "length": 1395 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3T1I9-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "Rpap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRRGDAHPDQLPPQDHRDVVMLDSLPDLPPALLPAPSKRARPSPGRPLPHDEDPEERLNRHDEHITAVLSKIVERDTSSVTVTLPVPSGVAFPPVFHRSQERQVKPAASSKRSIFAQEIAARRVSDNRAPSAEQVVPSPDAPEGAVPCETPSSKDRGSQLPGRSHSFHRPNLITGKGLRSQAAVQEVQTIHEENVARLQAMDPEEILKEQQQLLAQLDPSLVAFLRAHNHTREQTETKATKEQNPERPSVPVSKEEPIMSTCTGESGTRDKLEDKLEDKLQPRTPALKLPMTPNKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLEPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSHIVGRAQAGEFGDRLVGSVLRLLLDAGFLFLLRFSLDDRIDSVIAAAVRALRALLVAPGDEELLDSTFSWYHGASVFPMMPSHDDKEDEDEDEELTKEKVNRKTPEEGSRPPPDLARHDVIKGLLATNLLPRFRYVLEVTCPGPSVVLDILAVLIRLARHSLESAMRVLECPRLMETIVREFLPTSWSPIGVGPAPSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDVRSRLCRFIAEAPRDLALPFEEAEILTTEAFRLWAVAASYGQGGDLYRELYPVLMRALQTLPPELSTHPLQPLSMQRMASLLTLLTQLTLAASTQPEATSGSVESCVVAIPSSITWTHVSGLKPLVEPCLKQTLKFLRRPDVWNALGPVPSACLLFLGAYYQTWSQQSGLCPEDWLQDMERFLDEFLLPLLSQPPLGRMWDSLRDCSPLCNPLSCASTPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLINTLGQIHKGLCRQLAVVLTAPGLQNYFLQCVAPAPAPQLTPFSAWALRHEYHLQYLVLSLAQKAATSQPEPAASTALHHVMALVLLSRLLPGSEFLAHELLLSCVFRLGFLPENASGGPEAADFSDGLSLGNSGDPHCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELPRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGITMRVLQWVLVLESWRPEALWAVPPAARLARLMCVYLVDSELFRETPIQRLVAALLARLCQPQVLPNLKLDCPLPGLTSFPDLYASFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLAQLPVPLECYTEPAEDSLALLQLYFRALVTGALHARWCPVLYTVAVAHVNSFVFCQDPKSSDEVKAARRSMLQKVWLLADKDLRQHLLHYKLPNSSLPEGFELYPQLPRLRQQYLQTLPTEVLQNGGFKT", "length": 1400 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TE0-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "Rpap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAPPDRLPPQDHRDVVMLDNLPDLPPALLPAPAKRARPSPGHPLPHDEDPEERLNRHDQHITAVLSKIVERDTSSVTVTLPVPSGVAFPPVFHRSQERQVKPAASGKRSIFAQEIAARRVSGNRVTSAEQVVPSLDTPEGAVPCETPSFRDRSNQLPGRSHGFHRPNLVTGKGLRSKVAEQEVQTIHEENVARLQAMDPEEILKEQQQLLAQLDPSLVAFLRSHSQVQEQTGTKATKKQSPKRPSVLVTKEEPVTSTRTREPRTGDKLEEKPEATVEDKMEDKLQPRTPALKLPMTPSKDWLHMDTVELDKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALQVLSQIVGRAQAGEFGDRLVGSVLRLLLDAGFLFLLRFSLDDRVDSVIAAAVRALRTLLVAPGDEELLDRTFSWYHGASVFPLMPSQDDKEDEDEDEELETEKVKRKTPEEGSRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVILDILAVLIRLARHSLESAMRVLECPRLMETIVQEFLPTSWSPIGVGPTPSLYKVPCASAMKLLRVLASAGRNIAARLLSGFDVRSRLCRFIAEAPHDLALPPEEAEILTTEAFRLWAVAASYGQGGDLYRELYPVLLRALQTLPTELSAHPLQPLAMQRVAALFTLLTQLTLAASSIPPEPASGPAESCVPAIPSSVTWTQVSGLKPLVEPCLKQTLKFLPRPDVWNALGPVPSACLLFLGAYYQAWSRQSHLCPEDWLQDMERLLDESLLPLLSQPPLGSLWDSLRDCSPLCNPLSCASNPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLINTLVQSHKGLCGQLSAVLTAPGLQNYFLQCVAPAPAPQLTPFSAWALHHEYHLQYLVLSFAHKAATLQPEPAASTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPESASGGPEAADFSDGLSLGSSGDPQCRRGALLVQACRDLPSIRSCYLAHCSPARASLLSSQALYCGELLRVSSLLLPVPKEPLLATDWPFQPLIHLYHRASDTPSGPPAADTVGVAMRVLQWVLVLESWRPEVLWAVPPAARLARLMCVYLVDSELFRETPIQRLVAALLARLCRPQVLPNLKLDCPLPGLTSFPDLYASFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLPLLQLYFRALVTGTLRARWCPILYTVAVAHVNSFIFCQDPKSSDEVKTARRSMLQRTWLLTDEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQCLQTLPTEGLQNGGVKT", "length": 1409 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWH6-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "RPAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSRPKPGESEVDLLHFQSQFLAAGAAPAVQLVKKGNRGGGDANSDRPPLQDHRDVVMLDNLPDLPPALVPSPPKRARPSPGHCLPEDEDPEERLRRHDQHITAVLTKIIERDTSSVAVNLPVPSGVAFPAVFLRSRDTQGKSATSGKRSIFAQEIAARRIAEAKGPSVGEVVPNVGPPEGAVTCETPTPRNQGCQLPGSSHSFQGPNLVTGKGLRDQEAEQEAQTIHEENIARLQAMAPEEILQEQQRLLAQLDPSLVAFLRSHSHTQEQTGETASEEQRPGGPSANVTKEEPLMSAFASEPRKRDKLEPEAPALALPVTPQKEWLHMDTVELEKLHWTQDLPPVRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLAQVISRAQAGEFGDRLAGSVLSLLLDAGFLFLLRFSLDDRVDGVIATAIRALRALLVAPGDEELLDSTFSWYHGALTFPLMPSQEDKEDEDEDEECPAGKAKRKSPEEESRPPPDLARHDVIKGLLATSLLPRLRYVLEVTYPGPAVVLDILAVLIRLARHSLESATRVLECPRLIETIVREFLPTSWSPVGAGPTPSLYKVPCATAMKLLRVLASAGRNIAARLLSSFDLRSRLCRIIAEAPQELALPPEEAEMLSTEALRLWAVAASYGQGGYLYRELYPVLMRALQVVPRELSTHPPQPLSMQRIASLLTLLTQLTLAAGSTPAETISDSAEASLSATPSLVTWTQVSGLQPLVEPCLRQTLKLLSRPEMWRAVGPVPVACLLFLGAYYQAWSQQPSSCPEDWLQDMQRLSEELLLPLLSQPTLGSLWDSLRHCSLLCNPLSCVPALEAPPSLVSLGCSGGCPRLSLAGSASPFPFLTALLSLLNTLAQIHKGLCGQLAAILAAPGLQNYFLQCVAPGAAPHLTPFSAWALRHEYHLQYLALALAQKAAALQPLPATHAALYHGMALALLSRLLPGSEYLTHELLLSCVFRLEFLPERTSGGPEAADFSDQLSLGSSRVPRCGQGTLLAQACQDLPSIRNCYLTHCSPARASLLASQALHRGELQRVPTLLLPMPTEPLLPTDWPFLPLIRLYHRASDTPSGLSPTDTMGTAMRVLQWVLVLESWRPQALWAVPPAARLARLMCVFLVDSELFRESPVQHLVAALLAQLCQPQVLPNLNLDCRLPGLTSFPDLYANFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGALRALSLPLTQLPVSLECYTVPPEDNLALLQLYFRTLVTGALRPRWCPVLYAVAVAHVNSFIFSQDPQSSDEVKAARRSMLQKTWLLADEGLRQHLLHYKLPNSTLPEGFELYSQLPPLRQHYLQRLTSTVLQNGVSET", "length": 1393 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTX1-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "anon-69Ag", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKKLKPGESEEDVLRMAAEFNAERAKDPNFQPAAAFVRMDKAPKKSMFAQRREQAKLGRVTSTTEKNEEQIQPVPKEIIPQIPTSVPKERGSHVSQVLLDEIQENILGDVKGSKMDPSSLGNVLGELVERTEGTRRSAFPETKNVDSSKPLSIFAKQLLGAKSSTKEKSNKVSDFPRNDTSSIIKDAKLGKELHQENLNVLKQMNEQDILTEKERLLASLDPSLIALLSKKRQTTPNSKPPNPNSPKVIEAPPMPAQSTRAQDPQISSLTDGNPAIELLQESDKGNWLNFNLVEEHKLAWMRDIPAKISELKPGEQFNARFDWKGVLLPHTLKDQDASKQIDERELYLHGEEADRPGYALQELFRLARSTVLQQRLSAFGAIAGIFSIYNQGFYDQVLSLPISKIFFLLRFGLDDNAPAQLEVVSRALSNLFYNETDEVLLDHVHDNAYCHWQPTLEVLGNGSDGNGEDTDTNSIAFLQRYMKLLTTSKSVRAEVDEDESESRTSMDDFQLAETDLMDCLLRTNILQRIRFILVSVKPDNSTVESCLKLLIRIARTSTKVARQLANESHLIDTLFKHFLPSSSGSNQFYGQPQVLFLKLIRVLICHHLDIAKGISKGVLITRLQQYLFLQDNKVQMVRIQIEALRILRCLLLLGIVDRDIFRQFLPALRQLLDWHGNHCAFDGVGGSGLVRQHAAALLVALVASGESGACDVEGQKLLVEPLNNCCCGWMHAASRVAKIKDFSQMTLLSAALYAVGWFSRNSLLGTTSFLPFLRSILPKFVQSSGFIACVHDLVKGSIMLRRPIDRRHVHAPLPNVGAVLMHDYGPQLVVSETYPVHLLSNLWALLAISLDSGEKPLFEALIQPAVLEPLAEYLRQLSTQLNRVLATNFFARSELRFIHQLLTTDGIEIYLKRQQMLQLVYNYLCCLSTAHATQIKSIFERFIFNGDFVKLDESSLKLLQQSCLEMVYPHIIADNSEPSLSLSYTQAPILPTDWPFFQLRVILSNYLQNVQQRPAAIHSENQVVLMTLTFVRQLEREGLQIVSPLEKLMYLMIAFMGPDSQFLAPDLHELLRDCLMDFYRENAAHEFDFDAELVDKARFEPLYYLFVEHFEAASYGDELFSSLVLVPLAQKYDNKWRRRLWSEHVQAVRFINCDESMLMGGLFAYLEPVEEEPSLVKLYGDALAQKMVRPGSIAYRIAQHHFNHSKSVHKATLF", "length": 1215 }, "evidence": [ { "id": "A0A8V0ZBS1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBS1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" }, { "id": "PF08620", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08620" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 439, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" }, { "id": "PF08621", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08621" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 275, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS1" }, { "id": "PF25766", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25766" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1/MINIYO-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 1141, "end_pos": 1367, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 969 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 658, "end_pos": 660 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBT0-1", "uniprot_ac": "A0A8V0ZBT0", "uniprot_id": "A0A8V0ZBT0_CHICK", "mass": { "chemical_mass": 108650.0, "monoisotopic_mass": 108650.0 }, "refseq": {}, "gene_names": [ { "name": "CEP104", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 104 kDa", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for ciliogenesis and for structural integrity at the ciliary tip.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS5#function" }, { "database": "UniProtKB", "id": "ARBA00059645", "url": "https://www.uniprot.org/uniprotkb/ARBA00059645#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZPT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP104", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0", "locus": { "chromosome": "21", "start_pos": 925543, "end_pos": 912445, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021259", "url": "https://www.ensembl.org/id/ENSGALG00010021259" } ] } } ], "crossref": [ { "id": "A0A8V0ZBT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "419379", "url": "https://www.ncbi.nlm.nih.gov/gene/419379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZBS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBT0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIX8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13371:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13371:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHKIGFIVVSSSGHEDGFSAKELMVHAPTVNGWRSPRLCQYPQEIVLQLVERCRIRKLQLLAHQYMISSKIEFFISESLPEYFAPYQSERFHRLGYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALMILFCVQVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKEKESDFQKTKDQGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAWKSHLMGMDGCAMNLRRLSTINKTIPMQPGRTGGHYLKKPSPSRTKVRPPSIGSKIPTPRGGPNKSSGKTYSKQ", "length": 957, "header": "tr|A0A8V0ZBT0-1|A0A8V0ZBT0_CHICK Isoform 1 of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#A0A8V0ZBS5-1", "sequence": { "sequence": "MAVTKYPQEIVLQLVERCRIRKLQLLAHQYMISSKIEFFISESLPEYFAPYQSERFHRLGYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKEKESDFQKTKDQGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAWKSHLMGMDGCAMNLRRLSTINKTIPMQPGRTGGHYLKKPSPSRTKVRPPSIGSKIPTPRGGPNKSSGKTYSKQ", "length": 914, "header": "tr|A0A8V0ZBS5-1|A0A8V0ZBT0_CHICK Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "locus": { "chromosome": "21", "start_pos": 924092, "end_pos": 913428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051541.1", "url": "https://www.ensembl.org/id/ENSGALT00010051541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030732.1", "url": "https://www.ensembl.org/id/ENSGALP00010030732.1" } ] } }, { "isoform_ac": "A0A8V0ZBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#A0A8V0ZBT0-1", "sequence": { "sequence": "MPHKIGFIVVSSSGHEDGFSAKELMVHAPTVNGWRSPRLCQYPQEIVLQLVERCRIRKLQLLAHQYMISSKIEFFISESLPEYFAPYQSERFHRLGYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALMILFCVQVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKEKESDFQKTKDQGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAWKSHLMGMDGCAMNLRRLSTINKTIPMQPGRTGGHYLKKPSPSRTKVRPPSIGSKIPTPRGGPNKSSGKTYSKQ", "length": 957, "header": "tr|A0A8V0ZBT0-1|A0A8V0ZBT0_CHICK Isoform 1 of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "locus": { "chromosome": "21", "start_pos": 924092, "end_pos": 913330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051546.1", "url": "https://www.ensembl.org/id/ENSGALT00010051546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030737.1", "url": "https://www.ensembl.org/id/ENSGALP00010030737.1" } ] } }, { "isoform_ac": "A0A8V0ZIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#A0A8V0ZIX8-1", "sequence": { "sequence": "MPHKIGFIVVSSSGHEDGFSAKELMVHAPTVNGWRSPRLCQYPQEIVLQLVERCRIRKLQLLAHQYMISSKIEFFISESLPEYFAPYQSERFHRLGYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKEKESDFQKTKDQGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAEQEATI", "length": 882, "header": "tr|A0A8V0ZIX8-1|A0A8V0ZIX8_CHICK Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "locus": { "chromosome": "21", "start_pos": 923979, "end_pos": 913330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051555.1", "url": "https://www.ensembl.org/id/ENSGALT00010051555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030746.1", "url": "https://www.ensembl.org/id/ENSGALP00010030746.1" } ] } }, { "isoform_ac": "A0A8V0ZIY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#A0A8V0ZIY8-1", "sequence": { "sequence": "MPHKIGFIVVSSSGHEDGFSAKELMVHAPTVNGWRSPRLCQYPQEIVLQLVERCRIRKLQLLAHQYMISSKIEFFISESLPEYFAPYQSERFHRLGYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKVGMNISIFFFTGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAWKSHLMGMDGCAMNLRRLSTINKTIPMQPGRTGGHYLKKPSPSRTKVRPPSIGSKIPTPRGGPNKSSGKTYSKQ", "length": 949, "header": "tr|A0A8V0ZIY8-1|A0A8V0ZIY8_CHICK Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "locus": { "chromosome": "21", "start_pos": 924092, "end_pos": 913330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051549.1", "url": "https://www.ensembl.org/id/ENSGALT00010051549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030740.1", "url": "https://www.ensembl.org/id/ENSGALP00010030740.1" } ] } }, { "isoform_ac": "A0A8V0ZPT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0/entry#A0A8V0ZPT5-1", "sequence": { "sequence": "MPHKIGFIVVSSSGHEDGFSAKELMVHAPTVNGWRSPSYVPLSDNEKTGFKARELKSVYMDAVGQYLKLIFHKNYVNKYNLYSQVALVAINIIGDPADYSDDSNKYPSREKLIDHYLGSKSDDPALDGTYLGKPDSISPLDDLAFDMYQDPEVAQIIRRLDEKKHEAVHQERYDYAKKLKQAIADLQKVGERLGRYEVEKRYAVEKEDYDLAKKKKQQMDAYRLKVYQQLQLHNLLDAELMSRKPSELPVEPVIYDDSLQRTKATNSPSCENTELQTSQGELWKAESLLEEKPADPTSPEPVFRHQSTPPTLSHSTASREVFAQEEAEFLPYDERPLPAIQKHSEEAIRYLEPERTEGDISNTPRSGITGEPEPLSEKALREASPAIEVFGEALVSGAYSKSWSYREDALLAVYKKLMEMSVSTPKEDLRNMLRAAIFLVRRAIKDIVSSVFQASLKLLKMIITQYVPKHKLGKLETSHCVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMALWSEVKPLQIVPVHLVQLLKPNSPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHRVYEVRDVALRIIFGMYRKHKAAILEYLPPDDASIRKTVLYKTLFDGFTKIDGKLSEAEMRAQKKAATEEAERQKKEEIKVLQGQLAALKEIQAEVQAGKEKESDFQKTKDQGYKSPQPAAAEIPDDHSSVANYLDNLCIFCGERNESFTEEGLDLHYWKRCPMLTRCEHCKQVVEIASLTEHLLTECDKKDSFGKCQRCSEAFPKDELPKHIKSRTCNAAKPEHVANHCPLCHDNFSPGEEAWKSHLMGMDGCAMNLRRLSTINKTIPMQPGRTGGHYLKKPSPSRTKVRPPSIGSKIPTPRGGPNKSSGKTYSKQ", "length": 892, "header": "tr|A0A8V0ZPT5-1|A0A8V0ZPT5_CHICK Computationally mapped isoform of Centrosomal protein of 104 kDa OS=Gallus gallus OX=9031 GN=CEP104 PE=4 SV=1 CANONICAL=A0A8V0ZBT0-1" }, "locus": { "chromosome": "21", "start_pos": 924092, "end_pos": 913330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051552.1", "url": "https://www.ensembl.org/id/ENSGALT00010051552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030743.1", "url": "https://www.ensembl.org/id/ENSGALP00010030743.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" }, { "start_pos": 947, "end_pos": 949, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT0" }, { "id": "SM01349", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01349" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TOG", "eco_id": "ECO_0000259", "start_pos": 440, "end_pos": 697, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 786, "end_pos": 788 }, { "start_pos": 876, "end_pos": 878 }, { "start_pos": 905, "end_pos": 907 }, { "start_pos": 947, "end_pos": 949 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBT4-1", "uniprot_ac": "A0A8V0ZBT4", "uniprot_id": "A0A8V0ZBT4_CHICK", "mass": { "chemical_mass": 56717.0, "monoisotopic_mass": 56717.0 }, "refseq": { "ac": "XP_040556521", "name": "regulator of G-protein signaling 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556521" }, "gene_names": [ { "name": "RGS6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ] }, { "name": "RGS6", "type": "synonym", "evidence": [ { "id": "XP_040556521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556521" } ] } ], "protein_names": [ { "name": "Regulator of G protein signaling 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040556521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556521" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040556521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556521" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4", "locus": { "chromosome": "5", "start_pos": 26202559, "end_pos": 26437124, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021257", "url": "https://www.ensembl.org/id/ENSGALG00010021257" } ] } } ], "crossref": [ { "id": "A0A8V0ZBT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395618", "url": "https://www.ncbi.nlm.nih.gov/gene/395618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PWINDTV", "url": "https://omabrowser.org/oma/group/PWINDTV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIW5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIW9", "url": "https://www.orthodb.org/?gene=A0A8V0ZIW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIX4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040556521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPENEQGRRTSLEKFTRSVGKSLASKRLTGLMQSS", "length": 490, "header": "tr|A0A8V0ZBT4-1|A0A8V0ZBT4_CHICK Isoform 1 of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZBT4-1", "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPENEQGRRTSLEKFTRSVGKSLASKRLTGLMQSS", "length": 490, "header": "tr|A0A8V0ZBT4-1|A0A8V0ZBT4_CHICK Isoform 1 of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26419955, "end_pos": 26206264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051551.1", "url": "https://www.ensembl.org/id/ENSGALT00010051551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030742.1", "url": "https://www.ensembl.org/id/ENSGALP00010030742.1" } ] } }, { "isoform_ac": "A0A8V0ZHF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZHF6-1", "sequence": { "sequence": "MQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQHAQDVKASIESSIFMVPIHQAYRTPFVDVELNHSTEGKRENNHSLYASGSPFMSTFTS", "length": 449, "header": "tr|A0A8V0ZHF6-1|A0A8V0ZHF6_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26289444, "end_pos": 26223144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051538.1", "url": "https://www.ensembl.org/id/ENSGALT00010051538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030729.1", "url": "https://www.ensembl.org/id/ENSGALP00010030729.1" } ] } }, { "isoform_ac": "A0A8V0ZHG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZHG6-1", "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQVYFKRSVFFISHGCIRTLEDKTTFHMLQLLNHDLSKDF", "length": 464, "header": "tr|A0A8V0ZHG6-1|A0A8V0ZHG6_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26419955, "end_pos": 26211064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051548.1", "url": "https://www.ensembl.org/id/ENSGALT00010051548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030739.1", "url": "https://www.ensembl.org/id/ENSGALP00010030739.1" } ] } }, { "isoform_ac": "A0A8V0ZIV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZIV8-1", "sequence": { "sequence": "MIRIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLASKRLTGLMQSS", "length": 447, "header": "tr|A0A8V0ZIV8-1|A0A8V0ZIV8_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26323501, "end_pos": 26206264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051535.1", "url": "https://www.ensembl.org/id/ENSGALT00010051535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030726.1", "url": "https://www.ensembl.org/id/ENSGALP00010030726.1" } ] } }, { "isoform_ac": "A0A8V0ZIW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZIW5-1", "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKVNN", "length": 459, "header": "tr|A0A8V0ZIW5-1|A0A8V0ZIW5_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26419955, "end_pos": 26213060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051545.1", "url": "https://www.ensembl.org/id/ENSGALT00010051545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030736.1", "url": "https://www.ensembl.org/id/ENSGALP00010030736.1" } ] } }, { "isoform_ac": "A0A8V0ZIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZIW9-1", "sequence": { "sequence": "MRGLGPHCHSTAAPAQGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLASKRLTGLMQSS", "length": 427, "header": "tr|A0A8V0ZIW9-1|A0A8V0ZIW9_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26269099, "end_pos": 26206264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051534.1", "url": "https://www.ensembl.org/id/ENSGALT00010051534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030725.1", "url": "https://www.ensembl.org/id/ENSGALP00010030725.1" } ] } }, { "isoform_ac": "A0A8V0ZIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZIX4-1", "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQL", "length": 427, "header": "tr|A0A8V0ZIX4-1|A0A8V0ZIX4_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26419955, "end_pos": 26234281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051539.1", "url": "https://www.ensembl.org/id/ENSGALT00010051539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030730.1", "url": "https://www.ensembl.org/id/ENSGALP00010030730.1" } ] } }, { "isoform_ac": "A0A8V0ZPS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZPS3-1", "sequence": { "sequence": "MFQMTRTKHRTADEIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLASKRLTGLMQSS", "length": 458, "header": "tr|A0A8V0ZPS3-1|A0A8V0ZPS3_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26345513, "end_pos": 26206264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051537.1", "url": "https://www.ensembl.org/id/ENSGALT00010051537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030728.1", "url": "https://www.ensembl.org/id/ENSGALP00010030728.1" } ] } }, { "isoform_ac": "A0A8V0ZPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4/entry#A0A8V0ZPS5-1", "sequence": { "sequence": "MAQAPTDPSSAEAADPEESSPNMIVYRKIEDIITRMQDDKTGGVPIRTVKSFLSKIPSVVTGADIVQWLMKNLSIEDQGEAIHLGSLIAAQGYVFPISDHVLTLKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRMKNPQKVKKSVYGVTEESQPQSPVHVPSQPVRKTTKEDFRKQITFLNLQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDAALWDIEMSKEPSQQRVKRWGFSMDEVLKDPVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVTTRVEEIWQEFLAPGAQSAINLDSHSYEKTSQNVKDPGRYTYEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKKLLCFFIS", "length": 464, "header": "tr|A0A8V0ZPS5-1|A0A8V0ZPS5_CHICK Computationally mapped isoform of Regulator of G protein signaling 6 OS=Gallus gallus OX=9031 GN=RGS6 PE=4 SV=1 CANONICAL=A0A8V0ZBT4-1" }, "locus": { "chromosome": "5", "start_pos": 26419955, "end_pos": 26216896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051542.1", "url": "https://www.ensembl.org/id/ENSGALT00010051542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030733.1", "url": "https://www.ensembl.org/id/ENSGALP00010030733.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-GGA-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" } ], "orthologs": [ { "uniprot_canonical_ac": "P49758-4", "protein_name": "Regulator of G protein signaling 6", "gene_name": "RGS6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQGSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEESQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLITPAEPSNPWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "length": 472 }, "evidence": [ { "id": "A0A8V0ZBT4", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49801-1", "protein_name": "Regulator of G protein signaling 6", "gene_name": "Rgs6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKL", "length": 66 }, "evidence": [ { "id": "A0A8V0ZBT4", "url": "https://omabrowser.org/oma/group/A0A8V0ZBT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 115, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBT4" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 451, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"protein_names": [ { "name": "FANCD2 opposite strand", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCD2OS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV9", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBV9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31036:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31036:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"database": "Ensembl Transcript", "id": "ENSGALT00010047560.1", "url": "https://www.ensembl.org/id/ENSGALT00010047560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028162.1", "url": "https://www.ensembl.org/id/ENSGALP00010028162.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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"A0A8V0ZBW1-1", "uniprot_ac": "A0A8V0ZBW1", "uniprot_id": "A0A8V0ZBW1_CHICK", "mass": { "chemical_mass": 64531.0, "monoisotopic_mass": 64531.0 }, "refseq": { "ac": "XP_004943510", "name": "PEX5-related protein isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943510" }, "gene_names": [ { "name": "PEX5L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ] }, { "name": "PEX5L", "type": "synonym", "evidence": [ { "id": "XP_004943510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943510" } ] } ], "protein_names": [ { "name": "PEX5-related protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#names_and_taxonomy" } ] }, { "name": "PEX5-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#names_and_taxonomy" } ] }, { "name": "PEX5-related protein isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004943510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943510" } ] }, { "name": "Peroxin-5-related protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#names_and_taxonomy" } ] }, { "name": "Tetratricopeptide repeat-containing Rab8b-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943510" } ] }, { "annotation": "Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y4#function" }, { "database": "UniProtKB", "id": "ARBA00056540", "url": "https://www.uniprot.org/uniprotkb/ARBA00056540#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEX5L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1", "locus": { "chromosome": "9", "start_pos": 17077825, "end_pos": 16986423, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018055", "url": "https://www.ensembl.org/id/ENSGALG00010018055" } ] } } ], "crossref": [ { "id": "A0A8V0ZBW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "429155", "url": "https://www.ncbi.nlm.nih.gov/gene/429155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Y4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZBW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10130:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10130:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQGHMQLVNEQQESRPLLSPSIDDFLCETKPEAVARPVTSNTAVLSTGLDLLDLSEPTLQTQNKAKKSENPSRGEGLKTSTHRKKTDNSDLISVDTEQKVQTVRVSDKSSLDLVDIQTQIEKWDDVNFPGDKSCKVHPSAERTSSSSSSRAPSKELLWSTENRSQSELTNVKSTFDTDSTSELEVAPAIQVRSTKEQRWGGPLLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAPGQVTISTIEKGYYFHTENPFKDWPGAFEEGLKKMKEGDLPVTILYLEAAILQEPNDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQEAYQALRNWIKQNPKYKYIAKSKKGSPALTRRMSKTSDESSLLEEVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLNGEFNRAIDAFSAALTVRPEDYTLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPALSGNIWAALRIALSMMDQPELFQAANVGDLDILLRAFNLEP", "length": 575, "header": "tr|A0A8V0ZBW1-1|A0A8V0ZBW1_CHICK Isoform 1 of PEX5-related protein OS=Gallus gallus OX=9031 GN=PEX5L PE=3 SV=1 CANONICAL=A0A8V0ZBW1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#A0A8V0Z4Y4-1", "sequence": { "sequence": "MYQGHMQAVGETLKKKWLCLQKSDLTFALGKGSRAADKAVAMVMKEIPRDEAAEEKPLLTMASQLVNEQQESRPLLSPSIDDFLCETKPEAVARPVTSNTAVDIQTQIEKWDDVNFPGDKSCKVHPSAERTSSSSSSRAPSKELLWSTENRSQSELTNVKSTFDTDSTSELEVAPAIQVRSTKEQRWGGPLLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAPGQVTISTIEKGYYFHTENPFKDWPGAFEEGLKKMKEGDLPVTILYLEAAILQEPNDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQEAYQALRNWIKQNPKYKYIAKSKKGSPALTRRMSKTSDESSLLEEVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLNGEFNRAIDAFSAALTVRPEDYTLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPALSGNIWAALRIALSMMDQPELFQAANVGDLDILLRAFNLEP", "length": 562, "header": "tr|A0A8V0Z4Y4-1|A0A8V0Z4Y4_CHICK Computationally mapped isoform of PEX5-related protein OS=Gallus gallus OX=9031 GN=PEX5L PE=3 SV=1 CANONICAL=A0A8V0ZBW1-1" }, "locus": { "chromosome": "9", "start_pos": 17076141, "end_pos": 16986785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043659.1", "url": "https://www.ensembl.org/id/ENSGALT00010043659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025974.1", "url": "https://www.ensembl.org/id/ENSGALP00010025974.1" } ] } }, { "isoform_ac": "A0A8V0ZBW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#A0A8V0ZBW1-1", "sequence": { "sequence": "MYQGHMQLVNEQQESRPLLSPSIDDFLCETKPEAVARPVTSNTAVLSTGLDLLDLSEPTLQTQNKAKKSENPSRGEGLKTSTHRKKTDNSDLISVDTEQKVQTVRVSDKSSLDLVDIQTQIEKWDDVNFPGDKSCKVHPSAERTSSSSSSRAPSKELLWSTENRSQSELTNVKSTFDTDSTSELEVAPAIQVRSTKEQRWGGPLLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAPGQVTISTIEKGYYFHTENPFKDWPGAFEEGLKKMKEGDLPVTILYLEAAILQEPNDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQEAYQALRNWIKQNPKYKYIAKSKKGSPALTRRMSKTSDESSLLEEVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLNGEFNRAIDAFSAALTVRPEDYTLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPALSGNIWAALRIALSMMDQPELFQAANVGDLDILLRAFNLEP", "length": 575, "header": "tr|A0A8V0ZBW1-1|A0A8V0ZBW1_CHICK Isoform 1 of PEX5-related protein OS=Gallus gallus OX=9031 GN=PEX5L PE=3 SV=1 CANONICAL=A0A8V0ZBW1-1" }, "locus": { "chromosome": "9", "start_pos": 17076141, "end_pos": 16986785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043652.1", "url": "https://www.ensembl.org/id/ENSGALT00010043652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025971.1", "url": "https://www.ensembl.org/id/ENSGALP00010025971.1" } ] } }, { "isoform_ac": "A0A8V0ZBW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1/entry#A0A8V0ZBW8-1", "sequence": { "sequence": "MYQGHMQGKGSRAADKAVAMVMKEIPRDEAAEEKPLLTMASQLVNEQQESRPLLSPSIDDFLCETKPEAVARPVTSNTAVDIQTQIEKWDDVNFPGDKSCKVHPSAERTSSSSSSRAPSKELLWSTENRSQSELTNVKSTFDTDSTSELEVAPAIQVRSTKEQRWGGPLLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAPGQVTISTIEKGYYFHTENPFKDWPGAFEEGLKKMKEGDLPVTILYLEAAILQEPNDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQEAYQALRNWIKQNPKYKYIAKSKKGSPALTRRMSKTSDESSLLEEVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLNGEFNRAIDAFSAALTVRPEDYTLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPALSGNIWAALRIALSMMDQPELFQAANVGDLDILLRAFNLEP", "length": 540, "header": "tr|A0A8V0ZBW8-1|A0A8V0ZBW8_CHICK Computationally mapped isoform of PEX5-related protein OS=Gallus gallus OX=9031 GN=PEX5L PE=3 SV=1 CANONICAL=A0A8V0ZBW1-1" }, "locus": { "chromosome": "9", "start_pos": 17076141, "end_pos": 16986785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043665.1", "url": "https://www.ensembl.org/id/ENSGALT00010043665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025981.1", "url": "https://www.ensembl.org/id/ENSGALP00010025981.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" }, { "name": "peroxisome matrix targeting signal-1 binding", "id": "GO:0005052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into peroxisome matrix, docking", "id": "GO:0016560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"https://www.uniprot.org/uniprotkb/A0A8V0ZBW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VVLTRLEEKNSDLAEVEVDEVFGLMSHVAAKVPSHDAVPSRIVFLVEFLTAALYLLDVRCDVLLDVVLLQCLRSALHGVLLHLLRHVRVFDHCLSVTHGYGGWSRGRARGAGNGPCLP", "length": 118, "header": "tr|A0A8V0ZBW5-1|A0A8V0ZBW5_CHICK Isoform 1 of Dynein light chain OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW5/entry#A0A8V0ZBW5-1", "sequence": { "sequence": "VVLTRLEEKNSDLAEVEVDEVFGLMSHVAAKVPSHDAVPSRIVFLVEFLTAALYLLDVRCDVLLDVVLLQCLRSALHGVLLHLLRHVRVFDHCLSVTHGYGGWSRGRARGAGNGPCLP", "length": 118, "header": "tr|A0A8V0ZBW5-1|A0A8V0ZBW5_CHICK Isoform 1 of Dynein light chain OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBW5-1" }, "locus": { "chromosome": "15", "start_pos": 9295050, "end_pos": 9292728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051588.1", "url": "https://www.ensembl.org/id/ENSGALT00010051588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030772.1", "url": "https://www.ensembl.org/id/ENSGALP00010030772.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBY1-1", "uniprot_ac": "A0A8V0ZBY1", "uniprot_id": "A0A8V0ZBY1_CHICK", "mass": { "chemical_mass": 25021.0, "monoisotopic_mass": 25021.0 }, "refseq": {}, "gene_names": [ { "name": "PEBP4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1" } ] } ], "protein_names": [ { "name": "Phosphatidylethanolamine binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1", "locus": { "chromosome": "22", "start_pos": 1405931, "end_pos": 1340709, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019726", "url": "https://www.ensembl.org/id/ENSGALG00010019726" } ] } } ], "crossref": [ { "id": "A0A8V0ZBY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747939", "url": "https://www.ncbi.nlm.nih.gov/gene/101747939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747939", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKITSWM", "url": "https://omabrowser.org/oma/group/QKITSWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZBY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKGDRMGMERGSMGLLAAVLLAALLPGIAARGAQALWPDEPSHTCSFQSLSGKDSEFCRGNLEVIYPELGDVGCTYIPSCHQSRWRISREWGSPRVRYPRANKSKKYVLMLVDPDAPSRANPRSRFWRHWLLTDVPGAELRMGELRGRVLTEYARPTPPPRSGYHRYQLRLYEQPEGGRIRLGPEERISAGSWSLESFVERFQLGSPVASTQFLTKHHED", "length": 221, "header": "tr|A0A8V0ZBY1-1|A0A8V0ZBY1_CHICK Isoform 1 of Phosphatidylethanolamine binding protein 4 OS=Gallus gallus OX=9031 GN=PEBP4 PE=4 SV=1 CANONICAL=A0A8V0ZBY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1/entry#A0A8V0ZBY1-1", "sequence": { "sequence": "MPKGDRMGMERGSMGLLAAVLLAALLPGIAARGAQALWPDEPSHTCSFQSLSGKDSEFCRGNLEVIYPELGDVGCTYIPSCHQSRWRISREWGSPRVRYPRANKSKKYVLMLVDPDAPSRANPRSRFWRHWLLTDVPGAELRMGELRGRVLTEYARPTPPPRSGYHRYQLRLYEQPEGGRIRLGPEERISAGSWSLESFVERFQLGSPVASTQFLTKHHED", "length": 221, "header": "tr|A0A8V0ZBY1-1|A0A8V0ZBY1_CHICK Isoform 1 of Phosphatidylethanolamine binding protein 4 OS=Gallus gallus OX=9031 GN=PEBP4 PE=4 SV=1 CANONICAL=A0A8V0ZBY1-1" }, "locus": { "chromosome": "22", "start_pos": 1405608, "end_pos": 1348272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047619.1", "url": "https://www.ensembl.org/id/ENSGALT00010047619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028187.1", "url": "https://www.ensembl.org/id/ENSGALP00010028187.1" } ] } }, { "isoform_ac": "A0A8V0ZHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY1/entry#A0A8V0ZHX6-1", "sequence": { "sequence": "MGLLAAVLLAALLPGIAARGAQALWPDEPSHTCSFQSLSGKDSEFCRGNLEVIYPELGDVGCTYIPSCHQSRWRISREWGSPRVRYPRANKSKKYVLMLVDPDAPSRANPRSRFWRHWLLTDVPGAELRMGELRGRVLTEYARPTPPPRSGYHRYQLRLYEQPEGGRIRLGPEERISAGSWSLESFVERFQLGSPVASTQFLTKHHED", "length": 208, "header": "tr|A0A8V0ZHX6-1|A0A8V0ZHX6_CHICK Computationally mapped isoform of Phosphatidylethanolamine binding protein 4 OS=Gallus gallus OX=9031 GN=PEBP4 PE=4 SV=1 CANONICAL=A0A8V0ZBY1-1" }, "locus": { "chromosome": "22", "start_pos": 1405608, "end_pos": 1353128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047625.1", "url": "https://www.ensembl.org/id/ENSGALT00010047625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028190.1", "url": "https://www.ensembl.org/id/ENSGALP00010028190.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101747939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747939", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GL87-1", "protein_name": "Phosphatidylethanolamine binding protein 4", "gene_name": "Pebp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VTMKLVAAAFGLSLLVAGLWVGLSLTSNSDGGGKPGGGGGGGGGRGCFLPPLPKEDVSLCRNLEVFYMEMGNISCKVVPKCNQYRRKIMTWQSPIVKFHGALDGAQYLLVMVDPDAPSRSNPRMKYWRHWVVSNITGTDMKSGSIRGNIITDYQPPTPPPTTGLHRYQFFVYLQGDRDISIPESENENRGAWKLDKFLQQYGLQDPDTSTQFMTQFDGELPPDFGSINDGQDQPDQR", "length": 237 }, "evidence": [ { "id": "A0A8V0ZBY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96S96-1", "protein_name": "Phosphatidylethanolamine-binding protein 4", "gene_name": "PEBP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATYILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGSWKMDRFLNRFHLGEPEASTQFMTQNYQDSPTLQAPRERASEPKHKNQAEIAAC", "length": 227 }, "evidence": [ { "id": "A0A8V0ZBY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9G2-1", "protein_name": "Phosphatidylethanolamine-binding protein 4", "gene_name": "Pebp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMKLVAAALCLSLLAAGLWVGLSLTAESIEEGKPGGEKPGGGKPGGSGRGCFLPPLPKEDVSLCRNLEVFYMEMGNISCKIVPKCNLYRQKITAWQAPIVKFHTALDGALYLLVMVDPDAPSRSNPVMKYWRHWLVSNITGADMKSGSIRGNVLSDYSPPTPPPETGLHRYQFFVYLQGDRDISLSVEEKADLGGWNLDKFLQQYGLRDPDTSTQFMTQFDEELSSEFGRINDDQEQFNQK", "length": 242 }, "evidence": [ { "id": "A0A8V0ZBY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZBY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 158 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBZ6-1", "uniprot_ac": "A0A8V0ZBZ6", "uniprot_id": "A0A8V0ZBZ6_CHICK", "mass": { "chemical_mass": 64960.0, "monoisotopic_mass": 64960.0 }, "refseq": { "ac": "XP_046755096", "name": "SHC-transforming protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755096" }, "gene_names": [ { "name": "SHC4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ] }, { "name": "SHC4", "type": "synonym", "evidence": [ { "id": "XP_046755096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755096" } ] } ], "protein_names": [ { "name": "SHC adaptor protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6/entry#names_and_taxonomy" } ] }, { "name": "SHC-transforming protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046755096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755096" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6", "locus": { "chromosome": "10", "start_pos": 10394188, "end_pos": 10420836, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020132", "url": "https://www.ensembl.org/id/ENSGALG00010020132" } ] } } ], "crossref": [ { "id": "A0A8V0ZBZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426482", "url": "https://www.ncbi.nlm.nih.gov/gene/426482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426482", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426482", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNIDNQQ", "url": "https://omabrowser.org/oma/group/MNIDNQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBY6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZBZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZJG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046755096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHRAKYSRFRNDSVTSLDEGPQNIKGSSSSSHPSAPNLLAEDVPLGPQDACTTLCALIPRVANIKLANPSALPSLKGFCLGSKEVPRTKLTECVAVPGGPSSPELGCLSASYPQPGPEGPHLTPRPAGGCTGRGAAEAVSRLGGSLVTSGESAEEPGTTYSVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIRKRKPPVKFLSSVLGKSNLQFSGVNIKLTISTNSLTLINVDTQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAGNLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYENCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQIHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGDFLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPIISSGSEVSLKQPVRKESNMGHLHYHK", "length": 602, "header": "tr|A0A8V0ZBZ6-1|A0A8V0ZBZ6_CHICK Isoform 1 of SHC adaptor protein 4 OS=Gallus gallus OX=9031 GN=SHC4 PE=4 SV=1 CANONICAL=A0A8V0ZBZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6/entry#A0A8V0ZBY6-1", "sequence": { "sequence": "MKKREAISRLCEAVSGTNGAIRKRKPPVKFLSSVLGKSNLQFSGVNIKLTISTNSLTLINVDTQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAGNLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYENCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQIHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGDFLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPIISSGSEVSLKQPVRKESNMGHLHYHK", "length": 418, "header": "tr|A0A8V0ZBY6-1|A0A8V0ZBZ6_CHICK Computationally mapped isoform of SHC adaptor protein 4 OS=Gallus gallus OX=9031 GN=SHC4 PE=4 SV=1 CANONICAL=A0A8V0ZBZ6-1" }, "locus": { "chromosome": "10", "start_pos": 10408890, "end_pos": 10395269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048633.1", "url": "https://www.ensembl.org/id/ENSGALT00010048633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028724.1", "url": "https://www.ensembl.org/id/ENSGALP00010028724.1" } ] } }, { "isoform_ac": "A0A8V0ZBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6/entry#A0A8V0ZBZ6-1", "sequence": { "sequence": "MLHRAKYSRFRNDSVTSLDEGPQNIKGSSSSSHPSAPNLLAEDVPLGPQDACTTLCALIPRVANIKLANPSALPSLKGFCLGSKEVPRTKLTECVAVPGGPSSPELGCLSASYPQPGPEGPHLTPRPAGGCTGRGAAEAVSRLGGSLVTSGESAEEPGTTYSVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIRKRKPPVKFLSSVLGKSNLQFSGVNIKLTISTNSLTLINVDTQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAGNLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYENCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQIHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGDFLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPIISSGSEVSLKQPVRKESNMGHLHYHK", "length": 602, "header": "tr|A0A8V0ZBZ6-1|A0A8V0ZBZ6_CHICK Isoform 1 of SHC adaptor protein 4 OS=Gallus gallus OX=9031 GN=SHC4 PE=4 SV=1 CANONICAL=A0A8V0ZBZ6-1" }, "locus": { "chromosome": "10", "start_pos": 10420075, "end_pos": 10395269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048643.1", "url": "https://www.ensembl.org/id/ENSGALT00010048643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028734.1", "url": "https://www.ensembl.org/id/ENSGALP00010028734.1" } ] } }, { "isoform_ac": "A0A8V0ZJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6/entry#A0A8V0ZJG4-1", "sequence": { "sequence": "MLHRAKYSRFRNDSVTSLDEGPQNIKGSSSSSHPSAPNLLAEDVPLGPQDACTTLCALIPRVANIKLANPSALPSLKGFCLGSKEVPRTKLTECVAVPGGPSSPELGCLSASYPQPGPEGPHLTPRPAGGCTGRGAAEAVSRLGGSLVTSGESAEEPGTTYSVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIRKRKPPVKFLSSVLGKSNLQFSGVNIKLTISTNSLTLINVDTQQDTTDYVAYVAKDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAGNLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYENCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQIHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGDFLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPIISSGSEVSLKQPVRKESNMGHLHYHK", "length": 584, "header": "tr|A0A8V0ZJG4-1|A0A8V0ZJG4_CHICK Computationally mapped isoform of SHC adaptor protein 4 OS=Gallus gallus OX=9031 GN=SHC4 PE=4 SV=1 CANONICAL=A0A8V0ZBZ6-1" }, "locus": { "chromosome": "10", "start_pos": 10420075, "end_pos": 10395269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048647.1", "url": "https://www.ensembl.org/id/ENSGALT00010048647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028738.1", "url": "https://www.ensembl.org/id/ENSGALP00010028738.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426482", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LD01-1", "protein_name": "SHC-transforming protein 4 isoform X2", "gene_name": "Shc4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRERGQDGQAGLALYVGLFGHLGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSSPPPYPALAPHLPAEDATVPTQESPTALCTLIPRMASMKLANPVTFLSLKTFCLGTKEVPRLKLQESQDQATSSPASPETSLNRTGPAPTPHPHLHPDQVGRRTTPLSPDACPLPGPGQPIPRSRQDKHSPQHLLGSGLNYCVRYMGCIEVLKSMRSLDFGMRTQVTREAISRLCDAVPGAHGAIKKRKAPVKFLSAVLGKSNLQFSGMNIKLTVSTCSLTLMNLDNQQIIAKHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECHSGMAQDVISTIGQAFELRFKQYLKNPSVNTWESEEVRVEGTSEDRDHAYYNAMPRKLPPAGGISDVRIRVQATDQMAYCPIRCEKLCYLPVNSKCRGVYENCTGQRGSIGIPHQRGMHGDAALMKHACRVDLFDDPCYVNTQALQSTRGYAANQSSIQPHGSTWHIGKAPETVQPGARAQSMSSYSLPHIKQQLWSEECFHGRLSRGAAERLLVKDGDFLVRESMTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNSLPIISSGSEVSLKQPVRKDNNTRLLHYKK", "length": 630 }, "evidence": [ { "id": "A0A8V0ZBZ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZBZ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A3K2-1", "protein_name": "SHC adaptor protein 4", "gene_name": "Shc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPYAALTPHLPAEDATVPNQESPTALCTLIPRMASMKLANPVTFLSLKTFCLGSKQVPRLKLQENQDQTPSSPASPETSLNSTGPAPTPLPDQVGCRPTSLRPDTCPLPGPGEPNPRSKQDGPPLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGVHGAIKKRKAPVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGTAQDIISTIGQAFELRFKQYLKNPSLNTWEREEVLVDGTSEDRGHDYYNSIPGKQPPAGGIADVRIQVQADPVAYCPIRCEKLCYLPGTSTCSGVYKNCMGRSRPIGIPHERAMQSDAASLRHFWRVDLFDDPCYVNTQNMRGCAGNQSSTLPQGSPWHLGKAPETVQPGATAKPGSSHALPHIKQQLWSEECFHGRLSRGAAERLLVKDGDFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNSLPIISSGSEVSLKQPVKKHNNPGLSHSKK", "length": 622 }, "evidence": [ { "id": "A0A8V0ZBZ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZBZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BCR0-1", "protein_name": "SHC adaptor protein 4", "gene_name": "SHC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSPGVSTGSKGSPQPPYPTLAPHLPAEDAALASQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQESQDPAPSSPASPETSLNRAVPAPPPQRDPLGHRATSLTPDACPLPGPGEPTPRNRQDRHFVQHLLGLGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPAKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVPVDGHAEEREDHEYYNEIPGKQPPAGGVSDVRIKVQVTEQMAYCPIRCEKLCYLPGSSKSSSMYENCLEQSRAIGNAHERGVPSQREASLMKHSCGADLFDDPCYINTQALRSTLGPAGNQSSPHPLGSPWPQETAPETVQPGATAQPASSHSLPHIKQQLRNEDCYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNNPGLLHSNK", "length": 630 }, "evidence": [ { "id": "A0A8V0ZBZ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZBZ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6S5L8-1", "protein_name": "SHC-transforming protein 4", "gene_name": "SHC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPHPALAPHLPTEDATLPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLRSRQDRHFLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRKPPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEVHIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIQCEKLCYLPGNSKCSSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTPGSAGNQRSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKDNNPALLHSNK", "length": 630 }, "evidence": [ { "id": "A0A8V0ZBZ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZBZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6S5L9-1", "protein_name": "SHC-transforming protein 4", "gene_name": "Shc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPYPALAPHLPTEDATVSSQESPTALCTLIPRMASMKLANPITFLGLKTFCLGTKQVSRLKLQENQDQTPSRPASPESNLNRTGPAPAPDPDQVGRRPTSLRPDTCPLPGPGEPSPRSKQDGPPLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGAHGAIKKRKAPVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDTTDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTWEREEVLVDGAPEDRDHDYYNSIPGKQPPEGGISDVRIQAQATDQMAYCPIRCEKLCYLPGNSTCSGVYKNCMGRSRPIGIPHERAGQGDTPSLRHFWRVDLFDDPCYVNTQALQSMHSYAGNQSSALPQGSPWHLGKAPETVQPGATAKPGSALALPHIRQQLWDEECFHGKLSRGAAEKLLVKDGDFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNNLPIISSGSEVRLKQPIRKYDNTGLLPPKK", "length": 626 }, "evidence": [ { "id": "A0A8V0ZBZ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZBZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 326, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ6" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 589, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZBY8-1", "uniprot_ac": "A0A8V0ZBY8", "uniprot_id": "A0A8V0ZBY8_CHICK", "mass": { "chemical_mass": 5332.0, "monoisotopic_mass": 5332.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "TCL1 upstream neural differentiation-associated RNA", "type": "synonym", "evidence": [ { "id": "A0A8V0ZBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBY8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBY8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR054138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF21954", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21954", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVITSGNEEDKGSQEKESKEETILAMLGIIGTILNLIVIIFVYIYTTL", "length": 48, "header": "tr|A0A8V0ZBY8-1|A0A8V0ZBY8_CHICK Isoform 1 of TCL1 upstream neural differentiation-associated RNA OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBY8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8/entry#A0A8V0ZBY8-1", "sequence": { "sequence": "MVITSGNEEDKGSQEKESKEETILAMLGIIGTILNLIVIIFVYIYTTL", "length": 48, "header": "tr|A0A8V0ZBY8-1|A0A8V0ZBY8_CHICK Isoform 1 of TCL1 upstream neural differentiation-associated RNA OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZBY8-1" }, "locus": { "chromosome": "5", "start_pos": 45738118, "end_pos": 45737975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043706.1", "url": "https://www.ensembl.org/id/ENSGALT00010043706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026007.1", "url": "https://www.ensembl.org/id/ENSGALP00010026007.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"protein_names": [ { "name": "Galectin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Does not bind lactose, and may not bind carbohydrates.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0#function" }, { "database": "UniProtKB", "id": "ARBA00003397", "url": "https://www.uniprot.org/uniprotkb/ARBA00003397#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LGALSL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZBZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZBZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBZ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTFPGPSPCHRPSWGTQACASSQCPLRTHSQKNAKSRSREAASSLPKGCILPARPRTWKAKRGAMPGERQGSPRCPLHTEPTPVLRASRRGDGGGAGRWIMASQGPPSRVTTPIPIYRHAPRPPPTASRGSDWLSPEAPPPQHAVPPSFPAGGRHRAVEQYVGEIKGGLRPAMRITVIGMVPSNPKSFSVTLLCDPVDANRDVGMMFTVNFSEKSITRNARIDGKWGIEEKNIPYFPFIAGDTFKMELLCEHQQIKVLLDGRQLCDFTHRIQPLNLVKALQITGDVKLTKVA", "length": 294, "header": "tr|A0A8V0ZBZ0-1|A0A8V0ZBZ0_CHICK Isoform 1 of Galectin OS=Gallus gallus OX=9031 GN=LGALSL2 PE=4 SV=1 CANONICAL=A0A8V0ZBZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0/entry#A0A8V0ZBZ0-1", "sequence": { "sequence": "MASTFPGPSPCHRPSWGTQACASSQCPLRTHSQKNAKSRSREAASSLPKGCILPARPRTWKAKRGAMPGERQGSPRCPLHTEPTPVLRASRRGDGGGAGRWIMASQGPPSRVTTPIPIYRHAPRPPPTASRGSDWLSPEAPPPQHAVPPSFPAGGRHRAVEQYVGEIKGGLRPAMRITVIGMVPSNPKSFSVTLLCDPVDANRDVGMMFTVNFSEKSITRNARIDGKWGIEEKNIPYFPFIAGDTFKMELLCEHQQIKVLLDGRQLCDFTHRIQPLNLVKALQITGDVKLTKVA", "length": 294, "header": "tr|A0A8V0ZBZ0-1|A0A8V0ZBZ0_CHICK Isoform 1 of Galectin OS=Gallus gallus OX=9031 GN=LGALSL2 PE=4 SV=1 CANONICAL=A0A8V0ZBZ0-1" }, "locus": { "chromosome": "5", "start_pos": 28462148, "end_pos": 28457216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048157.1", "url": "https://www.ensembl.org/id/ENSGALT00010048157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028409.1", "url": "https://www.ensembl.org/id/ENSGALP00010028409.1" } ] } }, { "isoform_ac": "A0A8V0ZBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0/entry#A0A8V0ZBZ8-1", "sequence": { "sequence": "MMEGADRKAPPGTPAAEGSVCGTAVMTEKERCPKVEQYVGEIKGGLRPAMRITVIGMVPSNPKSFSVTLLCDPVDANRDVGMMFTVNFSEKSITRNARIDGKWGIEEKNIPYFPFIAGDTFKMELLCEHQQIKVLLDGRQLCDFTHRIQPLNLVKALQITGDVKLTKVA", "length": 169, "header": "tr|A0A8V0ZBZ8-1|A0A8V0ZBZ8_CHICK Computationally mapped isoform of Galectin OS=Gallus gallus OX=9031 GN=LGALSL2 PE=4 SV=1 CANONICAL=A0A8V0ZBZ0-1" }, "locus": { "chromosome": "5", "start_pos": 28462148, "end_pos": 28458104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048169.1", "url": "https://www.ensembl.org/id/ENSGALT00010048169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028414.1", "url": "https://www.ensembl.org/id/ENSGALP00010028414.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ0" }, { "id": "PS51304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galectin", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 294, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 128 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": 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"count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC00-1", "uniprot_ac": "A0A8V0ZC00", "uniprot_id": "A0A8V0ZC00_CHICK", "mass": { "chemical_mass": 85757.0, "monoisotopic_mass": 85757.0 }, "refseq": { "ac": "XP_015149958", "name": "transcription factor E4F1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149958" }, "gene_names": [ { "name": "E4F1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ] }, { "name": "E4F1", "type": "synonym", "evidence": [ { "id": "XP_015149958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149958" } ] } ], "protein_names": [ { "name": "Transcription factor E4F1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "E4F transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "Putative E3 ubiquitin-protein ligase E4F1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase E4F1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor E4F", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "p120E4F", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E4F1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149958" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149958.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149958" } ] }, { "annotation": "May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00#function" }, { "database": "UniProtKB", "id": "ARBA00053485", "url": "https://www.uniprot.org/uniprotkb/ARBA00053485#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "E4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00", "locus": { "chromosome": "14", "start_pos": 6509880, "end_pos": 6502217, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018095", "url": "https://www.ensembl.org/id/ENSGALG00010018095" } ] } } ], "crossref": [ { "id": "A0A8V0ZC00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC00", "database": "AlphaFoldDB", "categories": [] }, { "id": "416560", "url": "https://www.ncbi.nlm.nih.gov/gene/416560", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416560", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416560", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDSQNEM", "url": "https://omabrowser.org/oma/group/QDSQNEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC00", "url": "https://www.orthodb.org/?gene=A0A8V0ZC00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAVATSAGPAALTAAAAEEREGAAAAGSGPSAGSGAFLSLSAPFSEEDEDDVHKCGRCQAEFTSLEEFVQHKIQKRCQRGPEPPLGPEGPKVVPAVEESITVAHIVVEASSIAEEIGNASAIVGSGHIKEVIVAGDHVFENPNGHIDGDVTEEQGNPDDQEQDIATELIKVKLLVNKEGRYVCELCQKTFKTASILKAHMITHSSRKDYECKLCGTSFRTKGSLIRHHRRHTDERPYKCKKCGKSFRESGALTRHLKSLTPCTEKIRFNVNKEIVVNKDDLPTGSCSSNSETVPSIASESIETSPVIHLVTDAKGNVLHEVHVQMQELPVVDSKSLDEDQSHPKELPCEGETNSENLLRQAMRNSGIVIERVAVEEMQKADEAAVAATEEIKNEVVQAEEEPCGEQHAEVEQSEPTDAERTNGYKSYVCPHCNEAFSEAASLETHIKGHLDYKPFKCEECGKEFTKGYLLKKHQEVHVNERRFRCGECGKLYKTIAHVKGHRRVHSDERPYSCPKCGKRYKTKNAQQVHFRTHLEDKPYVCQYCSRGFREKGSLVRHIRHHTGEKPFKCYKCGRGFAEHGTLNRHLKTKGGCLLALKEVEEVMVSEESQSADNLAATVISEDPHTVLVEFSSVVADTQEYIIETATEDMETSEATEIMEGTRHEVDSHIMKVVQQIVNQANSGHQIIVQNVTVAENSEVTTDAADTITIATPESLTEQVAMTLASAIGEGAVLTTEGSIETEEATVTMVASEDIEIMEHTGEFVIASQEGEVEVQTVIV", "length": 781, "header": "tr|A0A8V0ZC00-1|A0A8V0ZC00_CHICK Isoform 1 of Transcription factor E4F1 OS=Gallus gallus OX=9031 GN=E4F1 PE=4 SV=1 CANONICAL=A0A8V0ZC00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00/entry#A0A8V0ZC00-1", "sequence": { "sequence": "MEAAVATSAGPAALTAAAAEEREGAAAAGSGPSAGSGAFLSLSAPFSEEDEDDVHKCGRCQAEFTSLEEFVQHKIQKRCQRGPEPPLGPEGPKVVPAVEESITVAHIVVEASSIAEEIGNASAIVGSGHIKEVIVAGDHVFENPNGHIDGDVTEEQGNPDDQEQDIATELIKVKLLVNKEGRYVCELCQKTFKTASILKAHMITHSSRKDYECKLCGTSFRTKGSLIRHHRRHTDERPYKCKKCGKSFRESGALTRHLKSLTPCTEKIRFNVNKEIVVNKDDLPTGSCSSNSETVPSIASESIETSPVIHLVTDAKGNVLHEVHVQMQELPVVDSKSLDEDQSHPKELPCEGETNSENLLRQAMRNSGIVIERVAVEEMQKADEAAVAATEEIKNEVVQAEEEPCGEQHAEVEQSEPTDAERTNGYKSYVCPHCNEAFSEAASLETHIKGHLDYKPFKCEECGKEFTKGYLLKKHQEVHVNERRFRCGECGKLYKTIAHVKGHRRVHSDERPYSCPKCGKRYKTKNAQQVHFRTHLEDKPYVCQYCSRGFREKGSLVRHIRHHTGEKPFKCYKCGRGFAEHGTLNRHLKTKGGCLLALKEVEEVMVSEESQSADNLAATVISEDPHTVLVEFSSVVADTQEYIIETATEDMETSEATEIMEGTRHEVDSHIMKVVQQIVNQANSGHQIIVQNVTVAENSEVTTDAADTITIATPESLTEQVAMTLASAIGEGAVLTTEGSIETEEATVTMVASEDIEIMEHTGEFVIASQEGEVEVQTVIV", "length": 781, "header": "tr|A0A8V0ZC00-1|A0A8V0ZC00_CHICK Isoform 1 of Transcription factor E4F1 OS=Gallus gallus OX=9031 GN=E4F1 PE=4 SV=1 CANONICAL=A0A8V0ZC00-1" }, "locus": { "chromosome": "14", "start_pos": 6509164, "end_pos": 6502496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043739.1", "url": "https://www.ensembl.org/id/ENSGALT00010043739.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026022.1", "url": "https://www.ensembl.org/id/ENSGALP00010026022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416560", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416560", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BH42-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4F1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAAALAPGGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKLQKACQRAPQEALPATPAAALLGREQVAPGAASSEEPITVAHIVVEAAALAGDINHSPDIVEAWSSSGLPRGFGASLPAIPSGRAGGGHIKEVIVASEAEPGDSEMAEGPGSSSERGPRLAAEGEQAQVKLLVNKDGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSMSKDVVVGKEDVPAGSGASTVGPVTPSSAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALAPEPTSPQELPCSSEGGRENLLHQAMQNSGIVLERAPGEEGALGPATPTASSPQSPGDAAPELPLLEVEQAETQVAGEASSVPRTHPCPQCSETFPTAATLEAHKRGHAGPRPFTCPQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPECGKCYKTKNAQQVHFRTHLEEKPHVCPFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPTAAAAVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDQEARLGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARSGTGGAEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 806 }, "evidence": [ { "id": "A0A8V0ZC00", "url": "https://omabrowser.org/oma/group/A0A8V0ZC00/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1MAM9-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4f1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGHEAGEGGVAAAAALSNGGFLGLPAPFSEEDEDDVHRCGRCQVEFTALEDFVQHKIQKTCHRAPQEALPTTSAATSLLGQEVVPTAAEEGPEEPITVAHIVVEATSLAEDMSHAPDLVGSGHIKEVIVAAEAEPGDGEMAEAPGSPNHQELGLIGEGEQAQVKLLVNKEGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSISKDTAVGKEEVPAGSSASTVGTVTSSVAGEPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALTPESADCEELPCSRENSRENLLHQAMQNSGIVLDRVAGEESTLQPAPPSGSSPQSLGDGPSELPLLEVEQIETQVASEAATVPRTHPCSQCSETFPSAATLEAHKRGHIGPRPFTCTQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPSAAATVLAEDPHTVLVEFSSVVADTQEYIIEATADDTETSEATEIIEGTQTEVDSHIMKVVQQIVHQAGAGHQIIVQNVTMDQEAALGSEAAAADTITIATPESLTEQVAMTLASAISEGTVLTARAGPNSTEQATVTMVSSEDIEILEHGGELVIASPEGQLEVQTVIV", "length": 783 }, "evidence": [ { "id": "A0A8V0ZC00", "url": "https://omabrowser.org/oma/group/A0A8V0ZC00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66K89-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4F1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGAMAVRVTAAHTAEAQAEAGREAGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPATPATTALLGQEVVPAAPGPEEPITVAHIVVEAASLAADISHASDLVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEDSPAAATTVLTEDPHTVLVEFSSVVADTQEYIIEATADDAETSEATEIIEGTQTEVDSHIMKVVQQIVHQASAGHQIIVQNVTMDEETALGPEAAAADTITIATPESLTEQVAMTLASAISEGTVLAARAGTSGTEQATVTMVSSEDIEILEHAGELVIASPEGQLEVQTVIV", "length": 784 }, "evidence": [ { "id": "A0A8V0ZC00", "url": "https://omabrowser.org/oma/group/A0A8V0ZC00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CCE9-1", "protein_name": "Transcription factor E4F1", "gene_name": "E4f1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAALSSGGFLGLPAPFSEEDEDDVHRCGRCQVEFTALEDFVQHKIQKTCHRAPQEALPTTPAATALLDQEVVPTAAEGGPDEPITVAHIVVEATSLAEDISHAPDLVGSGHIKEVIVAAEAEPGDVEMAEAPGSPNHQELGLLGEGEQAHVKLLVNKEGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSISKDTAVGKEEVPAGSSASTVGTVTSSVAGDPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALTPESPDSEELPCSSENSRENLLHQAMQNSGIVLERVAGEESALEPAPPSGSSPQCLGDGSPELPLLKVEQIETQVASEAATVPRTHPCPQCSETFPTAATLEAHKRGHIAPRPFTCTQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPSAAATVLAEDPHTVLVEFSSVVADTQEYIIEATADDTETSEATEIIEGTQTEVDSHIMKVVQQIVHQAGAGHQIIVQNVTMDQETALGSEATAADTITIATPESLTEQVAMTLASAISEGTVLTARAGPNSTEQATVTMVSSEDIEILEHGGELVIASPEGQLEVQTVIV", "length": 783 }, "evidence": [ { "id": "A0A8V0ZC00", "url": "https://omabrowser.org/oma/group/A0A8V0ZC00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "cAMP response element binding", "id": "GO:0035497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC00" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 183, "end_pos": 210, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 692, "end_pos": 694 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCK9-1", "uniprot_ac": "A0A8V0ZCK9", "uniprot_id": "A0A8V0ZCK9_CHICK", "mass": { "chemical_mass": 50198.0, "monoisotopic_mass": 50198.0 }, "refseq": {}, "gene_names": [ { "name": "SLC29A3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ] } ], "protein_names": [ { "name": "Solute carrier family 29 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC29A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9", "locus": { "chromosome": "6", "start_pos": 12514390, "end_pos": 12507044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019956", "url": "https://www.ensembl.org/id/ENSGALG00010019956" } ] } } ], "crossref": [ { "id": "A0A8V0ZCK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "423717", "url": "https://www.ncbi.nlm.nih.gov/gene/423717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423717", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSPWTTK", "url": "https://omabrowser.org/oma/group/GSPWTTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC03", "url": "https://www.orthodb.org/?gene=A0A8V0ZC03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZCK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10332:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10332:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-83936", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9755088", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755088", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZC03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFLFPCRASILGVRAQLSLFPRLVMCQHPNIHSMRLSMRVVTSVGAEQPGSSLVVELNQKESYQPLSARLESTLATAKTLPKDYFESYISIASTVPSVLCLLGNFLLVNRVPASVRILSSLFIMLSIFLVITVLVKVDTSSWTTCFFALTIGCVVVVSGASTIFTSSILGLSSRFPMRNSQALLAGQAMGGTVSAIASIIDLAAAADVTDSALAYFLTADIFLVVCIMVYLLLPRLEYSRYYMGSHWEHPSLATTSPSSPLEDQTEPGGSAHSLPQSTAVPPLRPILRKTAALGFCLFYVFFVSIIIFPSLSSSIQSVHQNSGSLWATKYFVPLTSFLLYNFADWCGRQITAWIQAPGPNSRLLPVLVLLRTIFLPLFILCNYQPRAHIRTVLFDHDIYPVAFTTLLGLSNGYLGTLTLVYGPKIMPKELAEAAGVVMSFYLVLGLALGSACSVLVVHLI", "length": 461, "header": "tr|A0A8V0ZCK9-1|A0A8V0ZCK9_CHICK Isoform 1 of Solute carrier family 29 member 3 OS=Gallus gallus OX=9031 GN=SLC29A3 PE=3 SV=1 CANONICAL=A0A8V0ZCK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9/entry#A0A8V0ZC03-1", "sequence": { "sequence": "MHPAGSSFPPDEEPLIEEPSVNRASQPKPSDHLYGAYVIFFLLGVGSLLPWNFFITAKHYWAYKLQNCSEQAEPAPSDLRDYFESYISIASTVPSVLCLLGNFLLVNRVPASVRILSSLFIMLSIFLVITVLVKVDTSSWTTCFFALTIGCVVVVSGASTIFTSSILGLSSRFPMRNSQALLAGQAMGGTVSAIASIIDLAAAADVTDSALAYFLTADIFLVVCIMVYLLLPRLEYSRYYMGSHWEHPSLATTSPSSPLEDQTEPGGSAHSLPQSTAVPPLRPILRKTAALGFCLFYVFFVSIIIFPSLSSSIQSVHQNSGSLWATKYFVPLTSFLLYNFADWCGRQITAWIQAPGPNSRLLPVLVLLRTIFLPLFILCNYQPRAHIRTVLFDHDIYPVAFTTLLGLSNGYLGTLTLVYGPKIMPKELAEAAGVVMSFYLVLGLALGSACSVLVVHLI", "length": 458, "header": "tr|A0A8V0ZC03-1|A0A8V0ZCK9_CHICK Computationally mapped isoform of Solute carrier family 29 member 3 OS=Gallus gallus OX=9031 GN=SLC29A3 PE=3 SV=1 CANONICAL=A0A8V0ZCK9-1" }, "locus": { "chromosome": "6", "start_pos": 12513284, "end_pos": 12507821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048188.1", "url": "https://www.ensembl.org/id/ENSGALT00010048188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028419.1", "url": "https://www.ensembl.org/id/ENSGALP00010028419.1" } ] } }, { "isoform_ac": "A0A8V0ZCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9/entry#A0A8V0ZCK9-1", "sequence": { "sequence": "MIFLFPCRASILGVRAQLSLFPRLVMCQHPNIHSMRLSMRVVTSVGAEQPGSSLVVELNQKESYQPLSARLESTLATAKTLPKDYFESYISIASTVPSVLCLLGNFLLVNRVPASVRILSSLFIMLSIFLVITVLVKVDTSSWTTCFFALTIGCVVVVSGASTIFTSSILGLSSRFPMRNSQALLAGQAMGGTVSAIASIIDLAAAADVTDSALAYFLTADIFLVVCIMVYLLLPRLEYSRYYMGSHWEHPSLATTSPSSPLEDQTEPGGSAHSLPQSTAVPPLRPILRKTAALGFCLFYVFFVSIIIFPSLSSSIQSVHQNSGSLWATKYFVPLTSFLLYNFADWCGRQITAWIQAPGPNSRLLPVLVLLRTIFLPLFILCNYQPRAHIRTVLFDHDIYPVAFTTLLGLSNGYLGTLTLVYGPKIMPKELAEAAGVVMSFYLVLGLALGSACSVLVVHLI", "length": 461, "header": "tr|A0A8V0ZCK9-1|A0A8V0ZCK9_CHICK Isoform 1 of Solute carrier family 29 member 3 OS=Gallus gallus OX=9031 GN=SLC29A3 PE=3 SV=1 CANONICAL=A0A8V0ZCK9-1" }, "locus": { "chromosome": "6", "start_pos": 12513284, "end_pos": 12509075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048184.1", "url": "https://www.ensembl.org/id/ENSGALT00010048184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028418.1", "url": "https://www.ensembl.org/id/ENSGALP00010028418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423717", "resource": "KEGG Pathway" }, { "id": "R-GGA-83936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "resource": "Reactome", "description": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" }, { "id": "R-GGA-9755088", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755088", "resource": "Reactome", "description": "Ribavirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SJ22-1", "protein_name": "Solute carrier family 29 member 3", "gene_name": "SLC29A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGACPQPAARERRPVCKPGSAGGGGAGGGAWRRSPASGPAEPGVAVAAAAGEAAAVAASDGDMAIISEDDFRHTSNSTYRTASSSLRADQEALLEKLLDRPPPSLQRPEDRFNGTYIIFFSLGIGGLLPWNFFVTAQEYWIFKLSNCSSPAAGEEPKDSDILNYFESYLAVASTVPSVLCLALNFLLVNRVPIRVRVLASLTVMLAIFIVMTVLVKVDTSSWTHSFFTITITCMAILSGTSTIFNSSVFGMTGSFPMRNSQALISGGAMGGTLSAVASLVDLAVASDVTDSTLAFFLTADIFLALCIGLYLLLPRLDYARYYMKPVWPTVFSGEEQLPQDSPSPTSVAPGSSDPQTPPLGPILKKTTGLGFCIIYLFFITSLIFPAICTNIESLSKGSGSPWSTKFFVPLTTFLLYNFADLCGRQVTAWIQVPGPRSKALPGLALLRTCFVPLFVFCNYQPRGHLHTVLFQSDVYPVLFTSLLGLSNGYLSTLALIYGPKIVPRELAEATGVVMTFYMGLGLVLGSACSALLVHLI", "length": 536 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P31381-1", "protein_name": "Nucleoside transporter FUN26", "gene_name": "FUN26", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEHSDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYFKHDIFKDTSIWAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIPLIFTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFVFIIDFIIR", "length": 517 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q80WK7-1", "protein_name": "Equilibrative nucleoside transporter 3", "gene_name": "Slc29a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFASEDIAYHSSNAVYRVPSNRHEADQEALLGKPLDYPAPGLQRPEDRFNGAYIIFFCLGIGGLLPWNFFVTAKEYWAFKLRNCSSPASGKDPEDADILNYFESYLAVASTVPSLLFLVANFLLVNRIRVHVRVLASLSVSLAIFVVMAVLVRVDTSSWTRGFFSIAMACMAIISSSSTIFNSSVYGLTGSFPMRNAQALISGGAMGGTVSAVASLVDLAASSDVRDSALAFFLTAAVFLGLCVGLYLLLPQLEYARYYMRPVVPIHVFSSEDSPPRDAPSTSSVAPASRAVHTPPLGPILKKTAGLGFCAVFLYFITALIFPAISTNIQPMHKGTGSPWTSKFYVPLTVFLLFNFADLCGRQVTAWIQVPGPRSKLLPILAVSRVCLVPLFLLCNYQPRSHLTLVLFQSDIYPILFTCLLGLSNGYLSTLVLMYGPKIVPRELAEATSVVMLFYMSLGLMLGSACAALLEHFI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VXY7-1", "protein_name": "Equilibrative nucleotide transporter 1", "gene_name": "ENT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTPISQRISQKSPKLRETKQIQMTTTDKSAGIVTDSEAGPETSLLLNPHEGSTKKAPSDSYHFAYIIYFTLGVGFLLPWNAFITAVDYFSYLYPSTAVDRIFAVIYMLVALVCLFVIVVFYAHKSLASFRINLGLLLFVIALLVVPVLDLVYVKGQVGLYAGFDVTSAAVALSGLGDALMQGGLIGVAGEMPERYMQAVVAGTAGSGVLVSLLRILTKAVYPQDPDGLRKSANLYFAVGIVVMVICAVFYNVAHKLPVIKFHEERKNEELIREKSEEKGSLTGLAWRTTLWDIVTKVKSHGFGIVLLYMVTLSIFPGYITEDVHSELLTDWYPILLIAAYNVFDLVGKCLTAVFMLEDEKIAVGGSIARLLFYPLFWGCLHGPMFLRTEIPVTILTCLLGLTNGYLTSVLMILAPKSVPLRHSETAGIVTVMFLVVGLASGSVIAWFWVI", "length": 450 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99P65-1", "protein_name": "Equilibrative nucleoside transporter 3", "gene_name": "Slc29a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFASEDNVYHSSNAVYRAPSNHQEADQEALLGKLLDYPAPGLQRPEDRFNGAYIIFFCLGIGGLLPWNFFVTAKEYWAYKLRNCSSPASGEDPEDMDILNYFESYLAVASTVPSLLFLVANFLLVNRVQVHVRVLASLSVSLAIFVVMIVLVKVDTSSWTRGFFSLTIACMAIISSSSTIFNSSVYGLTGSFPMRNAQALISGGAMGGTVSAVALLVDLAASSDVRDSTLAFFLMAAVFLGLCMGLYLLLSQLEYARYYMRPVAPVRVFSGEDNPSQDAPSASSVAPASRVMHTPPLGPILKKTASLGFCAVSLYFVTAFIIPAISTNIQSMHKGTGSPWTSKFFVPLTVFLLFNFADLCGRQVTAWIQVPGPRSKLLPGLVVSRFCLVPLFLLCNYQPRSHLTKVLFQSDIYPVLFTCLLGLSNGYLSTLVLIYGPKIVPRELAEATSVVMLFYMSVGLMLGSACAALLEHFI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZD2-1", "protein_name": "Equilibrative nucleoside transporter 3", "gene_name": "SLC29A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVVSEDDFQHSSNSTYRTTSSSLRADQEALLEKLLDRPPPGLQRPEDRFCGTYIIFFSLGIGSLLPWNFFITAKEYWMFKLRNSSSPATGEDPEGSDILNYFESYLAVASTVPSMLCLVANFLLVNRVAVHIRVLASLTVILAIFMVITALVKVDTSSWTRGFFAVTIVCMVILSGASTVFSSSIYGMTGSFPMRNSQALISGGAMGGTVSAVASLVDLAASSDVRNSALAFFLTATVFLVLCMGLYLLLSRLEYARYYMRPVLAAHVFSGEEELPQDSLSAPSVASRFIDSHTPPLRPILKKTASLGFCVTYVFFITSLIYPAICTNIESLNKGSGSLWTTKFFIPLTTFLLYNFADLCGRQLTAWIQVPGPNSKALPGFVLLRTCLIPLFVLCNYQPRVHLKTVVFQSDVYPALLSSLLGLSNGYLSTLALLYGPKIVPRELAEATGVVMSFYVCLGLTLGSACSTLLVHLI", "length": 475 }, "evidence": [ { "id": "A0A8V0ZCK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZCK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "nucleoside transmembrane transporter activity", "id": "GO:0005337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005337", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "cytidine transmembrane transporter activity", "id": "GO:0015212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "uridine transmembrane transporter activity", "id": "GO:0015213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "monoamine transmembrane transporter activity", "id": "GO:0008504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "guanine transmembrane transporter activity", "id": "GO:0015208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" }, { "name": "uracil transmembrane transporter activity", "id": "GO:0015210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015210", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "dopamine transport", "id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC19-1", "uniprot_ac": "A0A8V0ZC19", "uniprot_id": "A0A8V0ZC19_CHICK", "mass": { "chemical_mass": 44548.0, "monoisotopic_mass": 44548.0 }, "refseq": {}, "gene_names": [ { "name": "SLC35E2B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member E2B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35E2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19", "locus": { "chromosome": "21", "start_pos": 2007247, "end_pos": 1998442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020142", "url": "https://www.ensembl.org/id/ENSGALG00010020142" } ] } } ], "crossref": [ { "id": "A0A8V0ZC19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC19", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC19", "url": "https://www.orthodb.org/?gene=A0A8V0ZC19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTVTSAETPEEPNPPLLEEKPKGKSLFNLGSLFANRSEKFVIARSDSVPEENVLKITITETTVIESDLGIWNSHALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTFIGCIKMFVPCCLYQHKTRISYPPNFIMIMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVVMLIPAWIFFMDVPVIGKSGRSFSYNQDVVVLLLIDGVLFHLQSVTAYALMGKISPVTFSTVKHALSIWLSIIVFGNKITSLSAIGTVLVTVGVLLYNKAKQHQQETIHNLAAAAPQPAPSTAEDTEPLISKDLKPYD", "length": 406, "header": "tr|A0A8V0ZC19-1|A0A8V0ZC19_CHICK Isoform 1 of Solute carrier family 35 member E2B OS=Gallus gallus OX=9031 GN=SLC35E2B PE=4 SV=1 CANONICAL=A0A8V0ZC19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19/entry#A0A8V0ZC19-1", "sequence": { "sequence": "MSTVTSAETPEEPNPPLLEEKPKGKSLFNLGSLFANRSEKFVIARSDSVPEENVLKITITETTVIESDLGIWNSHALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTFIGCIKMFVPCCLYQHKTRISYPPNFIMIMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVVMLIPAWIFFMDVPVIGKSGRSFSYNQDVVVLLLIDGVLFHLQSVTAYALMGKISPVTFSTVKHALSIWLSIIVFGNKITSLSAIGTVLVTVGVLLYNKAKQHQQETIHNLAAAAPQPAPSTAEDTEPLISKDLKPYD", "length": 406, "header": "tr|A0A8V0ZC19-1|A0A8V0ZC19_CHICK Isoform 1 of Solute carrier family 35 member E2B OS=Gallus gallus OX=9031 GN=SLC35E2B PE=4 SV=1 CANONICAL=A0A8V0ZC19-1" }, "locus": { "chromosome": "21", "start_pos": 2005641, "end_pos": 2001240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048663.1", "url": "https://www.ensembl.org/id/ENSGALT00010048663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028754.1", "url": "https://www.ensembl.org/id/ENSGALP00010028754.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC19" }, { "id": "PF03151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sugar phosphate transporter", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 366, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC31-1", "uniprot_ac": "A0A8V0ZC31", "uniprot_id": "A0A8V0ZC31_CHICK", "mass": { "chemical_mass": 70979.0, "monoisotopic_mass": 70979.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN12", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ] } ], "protein_names": [ { "name": "Septin 12", "type": "synonym", "evidence": [ { "id": "A0A8V0ZC31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEPTIN12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31", "locus": { "chromosome": "14", "start_pos": 13072006, "end_pos": 13062442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018128", "url": "https://www.ensembl.org/id/ENSGALG00010018128" } ] } } ], "crossref": [ { "id": "A0A8V0ZC31", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC31", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416408", "url": "https://www.ncbi.nlm.nih.gov/gene/416408", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416408", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416408", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z4L7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC20", "url": "https://www.orthodb.org/?gene=A0A8V0ZC20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC31", "url": "https://www.orthodb.org/?gene=A0A8V0ZC31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSTAMVAEEDGTPRNHPAMPRPWDTALKKSFEAEDAGDAPGSPIASPLPVGATESHRALQPSPTPHSPLLRGQHRAGRAPGGIASFQSHAGPGSDGESLRSSSSSLESPAAPQLPAASLAADSCLKKVPSHGCVFPVEAECSLHVAAGHSSLPALDLHIAEEPGIPPPAPCPTPPWGARSPTAPPHTRLPSSSSSAEVAPGLPRTQLRVSLSASPRLARPTPPTATAATGPGEGLLPPAAPFKLVSQPQTVQVSSQPAFLGGMVLGPGTPLALRNMGSTGPTMGTCLVTPRGLSQAADGCCATATPEHGSSLEPQERSMEAAAVPQELPPDRGAHELFGYVGIEAVLEQMKVKTMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVSRKASQPSQEERIPKTVQLQSVTHVIEEKGVKMKLTVTDTPGFGDQINNENCWDPIIKYINEQYERYLREEILITRKRKIPDSRVHGCVYFIPPTGHWLRPLDLEFMRRLSKIVNVVPVIAKADTLTLEEREEFKQRIQQDLKAHSISVYPQEDFDEDPDDRLLNDRIREKIPFAVVGADQEHQVNGKRVLGRKTKWGIIEVENPEHCEFPMLRDLLIRSHLQDLKDITHNVHYESYRVRRLNESNRPAPSSNNGLPGRDEDGEESNL", "length": 655, "header": "tr|A0A8V0ZC31-1|A0A8V0ZC31_CHICK Isoform 1 of Septin 12 OS=Gallus gallus OX=9031 GN=SEPTIN12 PE=1 SV=1 CANONICAL=A0A8V0ZC31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31/entry#A0A8V0Z4L7-1", "sequence": { "sequence": "MARLSVKEHLDGILSDFEALKKSFEAEDAGDAPGSPIASPLPVGATESHRALQPSPTPHSPLLRGQHRAGRAPGGIASFQSHAGPGSDGESLRSSSSSLESPAAPQLPAASLAADSCLKKVPSHGCVFPVEAECSLHVAAGHSSLPALDLHIAEEPGIPPPAPCPTPPWGARSPTAPPHTRLPSSSSSAEVAPGLPRTQLRVSLSASPRLARPTPPTATAATGPGEGLLPPAAPFKLVSQPQTVQVSSQPAFLGGMVLGPGTPLALRNMGSTGPTMGTCLVTPRGLSQAADGCCATATPEHGSSLEPQERSMEAAAVPQELPPDRGAHELFGYVGIEAVLEQMKVKTMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVSRKASQPSQEERIPKTVQLQSVTHVIEEKGVKMKLTVTDTPGFGDQINNENCWDPIIKYINEQYERYLREEILITRKRKIPDSRVHGCVYFIPPTGHWLRPLDLEFMRRLSKIVNVVPVIAKADTLTLEEREEFKQRIQQDLKAHSISVYPQEDFDEDPDDRLLNDRIREKIPFAVVGADQEHQVNGKRVLGRKTKWGIIEVENPEHCEFPMLRDLLIRSHLQDLKDITHNVHYESYRVRRLNESNRPAPSSNNGLPGRDEDGEESNL", "length": 646, "header": "tr|A0A8V0Z4L7-1|A0A8V0Z4L7_CHICK Computationally mapped isoform of Septin 12 OS=Gallus gallus OX=9031 GN=SEPTIN12 PE=1 SV=1 CANONICAL=A0A8V0ZC31-1" }, "locus": { "chromosome": "14", "start_pos": 13071002, "end_pos": 13062967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043803.1", "url": "https://www.ensembl.org/id/ENSGALT00010043803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026054.1", "url": "https://www.ensembl.org/id/ENSGALP00010026054.1" } ] } }, { "isoform_ac": "A0A8V0ZC20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31/entry#A0A8V0ZC20-1", "sequence": { "sequence": "MEAAAVPQELPPDRGAHELFGYVGIEAVLEQMKVKTMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVSRKASQPSQEERIPKTVQLQSVTHVIEEKGVKMKLTVTDTPGFGDQINNENCWDPIIKYINEQYERYLREEILITRKRKIPDSRVHGCVYFIPPTGHWLRPLDLEFMRRLSKIVNVVPVIAKADTLTLEEREEFKQRQDLKAHSISVYPQEDFDEDPDDRLLNDRIREKIPFAVVGADQEHQVNGKRVLGRKTKWGIIEVENPEHCEFPMLRDLLIRSHLQDLKDITHNVHYESYRVRRLNESNRPAPSSNNGLPGRDEDGEESNL", "length": 333, "header": "tr|A0A8V0ZC20-1|A0A8V0ZC31_CHICK Computationally mapped isoform of Septin 12 OS=Gallus gallus OX=9031 GN=SEPTIN12 PE=1 SV=1 CANONICAL=A0A8V0ZC31-1" }, "locus": { "chromosome": "14", "start_pos": 13071002, "end_pos": 13069018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043795.1", "url": "https://www.ensembl.org/id/ENSGALT00010043795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026048.1", "url": "https://www.ensembl.org/id/ENSGALP00010026048.1" } ] } }, { "isoform_ac": "A0A8V0ZC31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31/entry#A0A8V0ZC31-1", "sequence": { "sequence": "MSRSTAMVAEEDGTPRNHPAMPRPWDTALKKSFEAEDAGDAPGSPIASPLPVGATESHRALQPSPTPHSPLLRGQHRAGRAPGGIASFQSHAGPGSDGESLRSSSSSLESPAAPQLPAASLAADSCLKKVPSHGCVFPVEAECSLHVAAGHSSLPALDLHIAEEPGIPPPAPCPTPPWGARSPTAPPHTRLPSSSSSAEVAPGLPRTQLRVSLSASPRLARPTPPTATAATGPGEGLLPPAAPFKLVSQPQTVQVSSQPAFLGGMVLGPGTPLALRNMGSTGPTMGTCLVTPRGLSQAADGCCATATPEHGSSLEPQERSMEAAAVPQELPPDRGAHELFGYVGIEAVLEQMKVKTMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVSRKASQPSQEERIPKTVQLQSVTHVIEEKGVKMKLTVTDTPGFGDQINNENCWDPIIKYINEQYERYLREEILITRKRKIPDSRVHGCVYFIPPTGHWLRPLDLEFMRRLSKIVNVVPVIAKADTLTLEEREEFKQRIQQDLKAHSISVYPQEDFDEDPDDRLLNDRIREKIPFAVVGADQEHQVNGKRVLGRKTKWGIIEVENPEHCEFPMLRDLLIRSHLQDLKDITHNVHYESYRVRRLNESNRPAPSSNNGLPGRDEDGEESNL", "length": 655, "header": "tr|A0A8V0ZC31-1|A0A8V0ZC31_CHICK Isoform 1 of Septin 12 OS=Gallus gallus OX=9031 GN=SEPTIN12 PE=1 SV=1 CANONICAL=A0A8V0ZC31-1" }, "locus": { "chromosome": "14", "start_pos": 13071002, "end_pos": 13062641, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043810.1", "url": "https://www.ensembl.org/id/ENSGALT00010043810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026059.1", "url": "https://www.ensembl.org/id/ENSGALP00010026059.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 284, "start_aa": "Thr", "end_pos": 284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr284", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416408", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZC31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC31" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 631, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 66, 175, 223, 284 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 630, "end_pos": 632 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC23-1", "uniprot_ac": "A0A8V0ZC23", "uniprot_id": "A0A8V0ZC23_CHICK", "mass": { "chemical_mass": 44342.0, "monoisotopic_mass": 44342.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "PDZ domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZC23", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZC23", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06750", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06750", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15012:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15012:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZC23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGRGGTRVPAMLPPYPRDGTLGEVGVPPIPLPAHPRRVEDGGKAALSQRLQPGDELVNISGTPLYGSRQEALILIKGSYRTLKMIVRRRSVPVLRPHSWHMAKLAEIRSDAPAMHCPPDAFSLSWPSGCDVSELSLQWNPLSRHCSTDRSSSIGSMESLDQPGHAYYEGTPSPVEHHSKRDSAYSSFSASSNTSDCALSLRPEDAANSEGPCKPPDPRYLQTAAEGADKRHAARHPVPPQPPVRRDSLRASPASGTDRRRVSVPATPLHAQGRWISDTFLCQRDKDGEGSSGRMLAACPPREQLSADQYYMLSSHPDRCAGDGGDRPYPESSAHRAPDAGMETAGDTTLLSPLQGHRHSAPEQLLASQLRALHVSTGSGRASPASPAPDNHRWTTSPLHAEPRGPGGLSPAP", "length": 413, "header": "tr|A0A8V0ZC23-1|A0A8V0ZC23_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZC23-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23/entry#A0A8V0ZC23-1", "sequence": { "sequence": "MPGRGGTRVPAMLPPYPRDGTLGEVGVPPIPLPAHPRRVEDGGKAALSQRLQPGDELVNISGTPLYGSRQEALILIKGSYRTLKMIVRRRSVPVLRPHSWHMAKLAEIRSDAPAMHCPPDAFSLSWPSGCDVSELSLQWNPLSRHCSTDRSSSIGSMESLDQPGHAYYEGTPSPVEHHSKRDSAYSSFSASSNTSDCALSLRPEDAANSEGPCKPPDPRYLQTAAEGADKRHAARHPVPPQPPVRRDSLRASPASGTDRRRVSVPATPLHAQGRWISDTFLCQRDKDGEGSSGRMLAACPPREQLSADQYYMLSSHPDRCAGDGGDRPYPESSAHRAPDAGMETAGDTTLLSPLQGHRHSAPEQLLASQLRALHVSTGSGRASPASPAPDNHRWTTSPLHAEPRGPGGLSPAP", "length": 413, "header": "tr|A0A8V0ZC23-1|A0A8V0ZC23_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZC23-1" }, "locus": { "chromosome": "4", "start_pos": 1814963, "end_pos": 1811377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048220.1", "url": "https://www.ensembl.org/id/ENSGALT00010048220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028434.1", "url": "https://www.ensembl.org/id/ENSGALP00010028434.1" } ] } }, { "isoform_ac": "A0A8V0ZCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC23/entry#A0A8V0ZCM7-1", "sequence": { "sequence": "MERAEGRPGAVQLVHVQLQGGAPWGFTLRGGLEHGEPLIVSKVEDGGKAALSQRLQPGDELVNISGTPLYGSRQEALILIKGSYRTLKMIVRRRSVPVLRPHSWHMAKLAEIRSDAPAMHCPPDAFSLSWPSGCDVSELSLQWNPLSRHCSTDRSSSIGSMESLDQPGHAYYEGTPSPVEHHSKRDSAYSSFSASSNTSDCALSLRPEDAANSEGPCKPPDPRYLQTAAEGADKRHAARHPVPPQPPRDKDGEGSSGRMLAACPPREQLSADQYYMLSSHPDRCAGDGGDRPYPESSAHRAPDAGMETAGDTTLLSPLQGHRHSAPEQLLASQLRALHVSTGSGRASPASPAPDNHRWTTS", "length": 361, "header": "tr|A0A8V0ZCM7-1|A0A8V0ZCM7_CHICK Computationally mapped isoform of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZC23-1" }, "locus": { "chromosome": "4", "start_pos": 1815265, "end_pos": 1811425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048227.1", "url": "https://www.ensembl.org/id/ENSGALT00010048227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028438.1", "url": "https://www.ensembl.org/id/ENSGALP00010028438.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC23", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZC33-1", "uniprot_ac": "A0A8V0ZC33", "uniprot_id": "A0A8V0ZC33_CHICK", "mass": { "chemical_mass": 32949.0, "monoisotopic_mass": 32949.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Connector enhancer of kinase suppressor of ras 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } 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{ "id": "IPR017874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12844", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12844", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12844:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12844:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZC64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMMKCLSGELAAFRRLKVYRCLFCQDKGNIACPCYFQHIQSSCLLPVILQHCRDRLILWMCLNLPFRQEVILKITSSKAPPPCGCGFPFHQKPDQQRQFWGKKKRKEKKKKKKRRKKREKKKEERKKKGKKCKRRKKIREKKKKRERESSLPLLSCIKYSSLKLYGVLAVFPPRWVDRQHPARSFLLFLPRTHQQSAAMEKVAGWYPAWHVALLYWTWLFLFTFGFTGAEITCRSCHSQVNPQQQHPQQGLPMHLKTDRGEKERWRIPGEQGGERGRGAGMDTEDAELQAPFDPALTGTKFSGWETRSWASEPEKAPGDSRPGAAAAPTGEYPQRGQAGGRRNSARRRRGRSPRGTAGPGGAAGREPGGSGAARFGLEELRLGSTTFALTGDSAHNQAMVHWSGQNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKIGLKTILSYLYVCPTNKRKIMLLTDPEVESSLLISTDEGATYQKYRLNFYIHSLLFHPKQEDWILAYSQDQKLFSSVEFGRRWLLLHEGVAPNRFYWSMMVSGREPDLVHLEAKTVDGHAQYITCKMQNCSEASQNKPFPGYIDHNSLIVQDDYVFVQLTSGGRPHYYVSYRRNAFTPIKLPKYSLPKDMHVISTDESQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVKSSQGLDGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWNLLQAPDTDLKGNPVHCLLPYCSLHLHLKVSENPYTSGNIASRDTAPSIIVASGNIGPELSDNDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAIKHTSLPIRHLWLSFDEGKSWSKYSFTSLPLFVDGILGEPGEETLIMTVFGHFSHRSEWQLVKIDYKSIFDRRCAEEDYWTWQLHSQGEACIMGAKRIYRKRKSEKKCMQGKYAGAMTSEPCVCTDADFDCDYGYERHRNGQCLPAFWYNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQQCPGKAPQGLRIITSDGKLTAEQGHNVTFLVQLEEGDLQRSLIQVDFGDGTAVSYANLSSTEDGIKHTYQNVGIFRVTVLVENSLGSDNAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWFGNNTEPLITLEGSITFTFSVEGMNTITVQVSAGNTILQDTKTIAVYEQFRSLRLSFSPNLDDYNPDIPEWRRDISRVVKRALVEATGISSKHILVAVLPGLPTSAELFILPYQDATGGNKRTEDLEQISEILIQKLNQNFVHFELKPGVRVLVHAAHLTAAPLVDLTPSHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGLNIYAQMQNEKDQEMVSPVSQRESIPNVPQSELMSPEQLVDEKLDVQPIEQPQATVQNPRKGNAAKVVWTEDFQKACGSPRGFKPRPGAEVFPQLLSPRAQKKSLPM", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZC64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC64" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "post-Golgi vesicle-mediated transport", "id": "GO:0006892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZC64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, 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"https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151739", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAREAARGQACLRRRLHGAEEAQQQQAVLVRKLQEKLLQYRSWCRELEQRLEAGGVSVQGSLSYRWETTEDHSLEKALLQLEEEQQRCENLAEVNTLLREHLDKANEVNLALKEDVGKLTADWMRAREELELKESEWRSEREFYDSYLRGEHNRLLSLWRQVLTFRRHFLEMKTATDRDLSELKAEQMRLSGSILVSCFRLNSGVQLWESVTLGRPVLKDQAQQQVEREINQEALEVMCLQVDEDLEKKELQDRVMELSALLVQSQKQNEEKEKTVKTLNDTVEMLEASRLEVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDSTVGIVQRPESSNVLSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNELVAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHTVIQAKEVIQGEVKCLQYELETERCLMKQEQENMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQEMLELWEKEKAEAEGQHEKKLFDMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKVLEVVHLQKILEEERGQWEEVEHQNKELQVCLQSLEGERSRWEEVERHNTEFQASLKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSSDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEETQMVEGKKNSLQAALQAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIKDIKEKKEKTESQQEQIQELEKQQELQRTAISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTVVSRMSKNLEDRDQEIKSLQELIQELEKQREIQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQVILQETKITLKERERKIEVLEKAVSKLQQQNDDTMMQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQSEQINVFHICEESRKVALTSCQNQVSLLEEVVRKRDEDNETLVQKLQHQEEELKTLQNLQLMLSEKKEEIKRHREEEKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLAGKEKELRRQSELLKQLTSALHWKDEGETLKKQIQKLQKWEEEEAENRRVLQERDQFLQRQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQEAFEGGENLSWLLEKKLLWQRLECLQQAVARLEHEKSELKQLNVELKITLEQVEHERRRLKRSCRRQSQPNANRFSLSESDEDKMPASRKEEARALCSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAAVLEAETQKLDLSLNHTLALISLDCRSPERQLLHSAVRSTTRDGLR", "length": 2594, "header": "tr|A0A8V0ZC94-1|A0A8V0ZC94_CHICK Isoform 1 of Centrosomal protein 250 OS=Gallus gallus OX=9031 GN=CEP250 PE=4 SV=1 CANONICAL=A0A8V0ZC94-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC94/entry#A0A8V0ZC94-1", "sequence": { "sequence": "MAAREAARGQACLRRRLHGAEEAQQQQAVLVRKLQEKLLQYRSWCRELEQRLEAGGVSVQGSLSYRWETTEDHSLEKALLQLEEEQQRCENLAEVNTLLREHLDKANEVNLALKEDVGKLTADWMRAREELELKESEWRSEREFYDSYLRGEHNRLLSLWRQVLTFRRHFLEMKTATDRDLSELKAEQMRLSGSILVSCFRLNSGVQLWESVTLGRPVLKDQAQQQVEREINQEALEVMCLQVDEDLEKKELQDRVMELSALLVQSQKQNEEKEKTVKTLNDTVEMLEASRLEVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDSTVGIVQRPESSNVLSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNELVAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHTVIQAKEVIQGEVKCLQYELETERCLMKQEQENMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQEMLELWEKEKAEAEGQHEKKLFDMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKVLEVVHLQKILEEERGQWEEVEHQNKELQVCLQSLEGERSRWEEVERHNTEFQASLKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSSDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEETQMVEGKKNSLQAALQAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIKDIKEKKEKTESQQEQIQELEKQQELQRTAISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTVVSRMSKNLEDRDQEIKSLQELIQELEKQREIQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQVILQETKITLKERERKIEVLEKAVSKLQQQNDDTMMQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQSEQINVFHICEESRKVALTSCQNQVSLLEEVVRKRDEDNETLVQKLQHQEEELKTLQNLQLMLSEKKEEIKRHREEEKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLAGKEKELRRQSELLKQLTSALHWKDEGETLKKQIQKLQKWEEEEAENRRVLQERDQFLQRQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQEAFEGGENLSWLLEKKLLWQRLECLQQAVARLEHEKSELKQLNVELKITLEQVEHERRRLKRSCRRQSQPNANRFSLSESDEDKMPASRKEEARALCSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAAVLEAETQKLDLSLNHTLALISLDCRSPERQLLHSAVRSTTRDGLR", "length": 2594, "header": "tr|A0A8V0ZC94-1|A0A8V0ZC94_CHICK Isoform 1 of Centrosomal protein 250 OS=Gallus gallus OX=9031 GN=CEP250 PE=4 SV=1 CANONICAL=A0A8V0ZC94-1" }, "locus": { "chromosome": "20", "start_pos": 1559099, "end_pos": 1524987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051795.1", "url": "https://www.ensembl.org/id/ENSGALT00010051795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030897.1", "url": "https://www.ensembl.org/id/ENSGALP00010030897.1" } ] } }, { "isoform_ac": "A0A8V0ZJE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC94/entry#A0A8V0ZJE6-1", "sequence": { "sequence": "MWSPQHSRGIDLLLLQYRSWCRELEQRLEAGGVSVQGSLSYRWETTEDHSLEKALLQLEEEQQRCENLAEVNTLLREHLDKANEVNLALKEDVGKLTADWMRAREELELKESEWRSEREFYDSYLRGEHNRLLSLWRQVLTFRRHFLEMKTATDRDLSELKAEQMRLSGSILVSCFRLNSGVQLWESVTLGRPVLKDQAQQQVEREINQEALEVMCLQVDEDLEKKELQDRVMELSALLVQSQKQNEEKEKTVKTLNDTVEMLEASRLEVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDSTVGIVQRPESSNVLSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNELVAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHTVIQAKEVIQGEVKCLQYELETERCLMKQEQENMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQEMLELWEKEKAEAEGQHEKKLFDMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKVLEVVHLQKILEEERGQWEEVEHQNKELQVCLQSLEGERSRWEEVERHNTEFQASLKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSSDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEETQMVEGKKNSLQAALQAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIKDIKEKKEKTESQQEQIQELEKQQELQRTAISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTVVSRMSKNLEDRDQEIKSLQELIQELEKQREIQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQVILQETKITLKERERKIEVLEKAVSKLQQQNDDTMMQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQSEQINVFHICEESRKVALTSCQNQVSLLEEVVRKRDEDNETLVQKLQHQEEELKTLQNLQLMLSEKKEEIKRHREEEKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLAGKEKELRRQSELLKQLTSALHWKDEGETLKKQIQKLQKWEEEEAENRRVLQERDQFLQRQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQEAFEGGENLSWLLEKKLLWQRLECLQQAVARLEHEKSELKQLNVELKITLEQVEHERRRLKRSCRRQSQPNANRFSLSESDEDKMPASRKEEARALCSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAAVLEAETQKLDLSLNHTLALISLDCRSPERQLLHSAVRSTTRDGLR", "length": 2570, "header": "tr|A0A8V0ZJE6-1|A0A8V0ZJE6_CHICK Computationally mapped isoform of Centrosomal protein 250 OS=Gallus gallus OX=9031 GN=CEP250 PE=4 SV=1 CANONICAL=A0A8V0ZC94-1" }, "locus": { "chromosome": "20", "start_pos": 1558153, "end_pos": 1524987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051785.1", "url": "https://www.ensembl.org/id/ENSGALT00010051785.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030890.1", "url": "https://www.ensembl.org/id/ENSGALP00010030890.1" } ] } }, { "isoform_ac": "A0A8V0ZJF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC94/entry#A0A8V0ZJF3-1", "sequence": { "sequence": "MLLQYRSWCRELEQRLEAGGVSVQGSLSYRWETTEDHSLEKALLQLEEEQQRCENLAEVNTLLREHLDKANEVNLALKEDVGKLTADWMRAREELELKESEWRSEREFYDSYLRGEHNRLLSLWRQVLTFRRHFLEMKTATDRDLSELKAEQMRLSGSILVSCFRLNSGVQLWESVTLGRPVLKDQAQQQVEREINQEALEVMCLQVDEDLEKKELQDRVMELSALLVQSQKQNEEKEKTVKTLNDTVEMLEASRLEVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDSTVGIVQRPESSNVLSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNELVAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHTVIQAKEVIQGEVKCLQYELETERCLMKQEQENMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQEMLELWEKEKAEAEGQHEKKLFDMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKVLEVVHLQKILEEERGQWEEVEHQNKELQVCLQSLEGERSRWEEVERHNTEFQASLKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSSDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEETQMVEGKKNSLQAALQAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIKDIKEKKEKTESQQEQIQELEKQQELQRTAISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTVVSRMSKNLEDRDQEIKSLQELIQELEKQREIQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQVILQETKITLKERERKIEVLEKAVSKLQQQNDDTMMQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQSEQINVFHICEESRKVALTSCQNQVSLLEEVVRKRDEDNETLVQKLQHQEEELKTLQNLQLMLSEKKEEIKRHREEEKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLAGKEKELRRQSELLKQLTSALHWKDEGETLKKQIQKLQKWEEEEAENRRVLQERDQFLQRQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQEAFEGGENLSWLLEKKLLWQRLECLQQAVARLEHEKSELKQLNVELKITLEQVEHERRRLKRSCRRQSQPNANRFSLSESDEDKMPASRKEEARALCSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAAVLEAETQKLDLSLNHTLALISLDCRSPERQLLHSAVRSTTRDGLR", "length": 2558, "header": "tr|A0A8V0ZJF3-1|A0A8V0ZJF3_CHICK Computationally mapped isoform of Centrosomal protein 250 OS=Gallus gallus OX=9031 GN=CEP250 PE=4 SV=1 CANONICAL=A0A8V0ZC94-1" }, "locus": { "chromosome": "20", "start_pos": 1558589, "end_pos": 1524987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051791.1", "url": "https://www.ensembl.org/id/ENSGALT00010051791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030895.1", "url": "https://www.ensembl.org/id/ENSGALP00010030895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419138", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419138", "resource": "KEGG Pathway" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LVR8-1", "protein_name": "Centrosome-associated protein CEP250 isoform X1", "gene_name": "Cep250", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGGLIPQRWEGVEEPNLEQLLVRLEEEQQRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2425 }, "evidence": [ { "id": "A0A8V0ZC94", "url": "https://omabrowser.org/oma/group/A0A8V0ZC94/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9S885-1", "protein_name": "Centrosomal protein 250", "gene_name": "CEP250", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METGGPGLNNMKPRSLQLVLEEQVLALQQQMAENQAASWRKLKSSQEAQQRQAALVRKLQAKVLQYRSWCQELEKRLEATGCRCENLVEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLGLWREVVTFRRHFLEMKSATDRDLTELKAEHARLSGSLLTSCLRLTVGVPPSRESDGSGRLNGNEPSQLMLLLAKTQELEREAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRATMEILEANHAELMEHEASLSRNAQEEKLSLQQVIQDITQAMVEEEDSMAQGSSHESSLQLDPGGFSSRFDSQQPDKAVSLVRSVLTQRRQAVQDLRQQLSGCQEAVSSWQQQHHQWEEEGEALRQRLQQLTGERDTLAGQTVDLQGEVDSLSRERELLQKTREELQQQLEVLEQEAWRLRRTNMELQLQGDSAQGEKEEQQEELHLAVRERERLQETLVVLEARQSESLSELICLREALESSRLEGELLRQEQTEVTAALARAEQSIVELSSAENSLKAEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEQEKQSVCRRMEAAEQARSTLQVDLAEAERSREALWEKNSHLEAQLQKTEETRAELQADLRGIQEEKEEIQEKLSETYHQQEAASAQIEQLKQETTRQEEMLAREVQEKEALAREKAALEVRLQAVERDRQELAEQLLGLSSAKEVLESSLFEAQQQNSLTEVTKGQLEVQIQTVTQAKEVIQGEVKCLQLELDTERSRAEQARDTAARQLAQAEQEGQAALQQLKSAHEEEVNRLQEKWEEERSRHRQELEKVLESLEREKMELEARLREQQAEMEAMRAQREEERAEAESALCQMQLETEKERMSLLETLLQTQKELAEASQQLERLRQDMKVQQLKEQETTGMLQTQLQEAQQALEQAAQQHRDSLATLQQEGRVLLQDKTDLQKQVEDLKSQLLSKEASQRFVDQEVQEKLREAQECSRIQKELEREKASLTLSLVEKEQRLLVLQEADSVQQQELSSLRQDMQEAQAGQKELSTQVELLKQEVKEKEADFLAQETQLLEELEASRVTEQQLRASLWAQETKVAQLQLRLRSTESRLEALVAEQQPGHQAQVQLASLYSVLQQALGSACESRLELNGGGDSAPSLWGPEPDQNGARILFKRGPLLTALSVEAVAAALHKLHQDLWKTQQARDDLRDQAQKLEQRLSDMEAEKSQVHTELQALQRQLSQNEEEKSKWEGKQNSLESELMELRETVASLQSRLQQAELQGVEAQNERKLLQAAKESLTAQVEHLQASITEARAQASAAVALEEDLRMARSALKLKNEEVASERQRAQALQEQGELKVAQGKALQENLARLAQALSEREGEVETLQGKIEELEKQREMQKAVLEVLSLDLKKRNREVDLQQGQIQELEECRSVLEHLPVAVQEREQQLALQRERIRELEKDRETQTSILEHHLLELEKKVQVIESQKGQIQDLKKQLVTTECLALELEEKRHKTESQQKAIEELEGQREAQRVALTHLTLDLEERSQELLAQGNRIQELEGHSTLLASELQEKEQEAMAQQDQIRDLQRQKERLSQDLERREQELVLLKERTQSLEDQRSRQTKILEEDLEQIKLALRERGRELVSQRQLRQEWAEEGKGQSKAQRGSLEHMKLILRDKEKEVECQQEHIQELREHRDQLEQELQGLHRKVSETSLLLTQREQEIAVLQQHLQEAQDQGELKEQELQGQLEETQRVLVQRTQELQALQQQEAQDQEKNVKEQADSLQTALEQAHAALEERRAELEEHKEHARRLQEELAVEGRRSQALEEVLGDLRAEAREQEKVLRALQQQCADQAQEHEAEARGLRDSWLQAEALLDARDRELEALRAEGQASQRQEEAARGQAEALQKALGQAQAALREKEQHLHGQAELSRNLEASTATLQAALDSCQAQARQLEETLRKREGEIQDGDLRHQETVQQLQQALAQRDKELRELRRQGQLLEKSLAQEKQERRHEREGEEVRGLRESLRELQRTLAQKEDELLELREAQQRKDLEDAPHSHKTSPREEPSSPLDSSGPRLQRELERLQRALRQTEAREIEWREKAQHLALSLAQSKASVSSLQEAALLLQASVLERDSEQQRLQDELELTRQALEKERLHSLGLTSQAEQGPGGEPGIRLGEVSEVKMEPSPEAEEKQRWEQRLEHLQRAVAQLEVDRSRLQHHNTQLRTTLEQVERERRKLKRESMRASRAGVLESSGATTPSPTPQDGRGGQKVSSDATHMAELQKEVALLRAQLALERKQKQDYIARSVQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRKLDESLTQSLTSPGPILLCRSPSPAQGASR", "length": 2408 }, "evidence": [ { "id": "A0A8V0ZC94", "url": "https://omabrowser.org/oma/group/A0A8V0ZC94/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M7J7-1", "protein_name": "Centrosomal protein 250", "gene_name": "Cep250", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METGSPGLNMKPQSLQLVLEEQVLALQQQMAQNQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEATGGLIPQRWESVEEPNLEQLLIRLEEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRMEQEFFKGYLRGEHGRLLSVWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTCCLRLTLRAQSRDSSGSGRSDESEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAGSLEARETMNSSPTQQDGRGSQRGSSDSMLMVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETKKLDESLNQSLTSPAPFLHPSLDTTQNTHR", "length": 2428 }, "evidence": [ { "id": "A0A8V0ZC94", "url": "https://omabrowser.org/oma/group/A0A8V0ZC94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60952-1", "protein_name": "Centrosome-associated protein CEP250", "gene_name": "Cep250", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METGSPGLNMKPQSLQLVLEGQVLALQQQMAENQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEATGGLIPQRWESVEEPNLEQLLIRLEEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELVRKESQWRMEQEFFKGYLRGEHGRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTCCLRLTLRAQSRESSGSGRTEESEPARLLLLVAKTQALEKEAHEKSQELMQLKSHGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMEILETNHAELMEHEASLSRNAQEEKLSLQQVIKAITQALASVEEEDTVTQSSGHEDSLQSDCNGLSQFDPQDPDRALTLVQSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHDQWEEEGRALREKLQKLTGERDALAGQTVGLQGEVDSLSRERELLQKARGELQQQLEVLEQEAWRLRRMNMELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELLTLREALESSRLEGELLKQERVEVAAALARAEQSIVELSGSENSLKAEVADLRAAAVKLGALNEALALDKVELNQQLLQLEQENQSLCSRVEAAEQLRSALQVDLAEAERRREALWEKKTQLETQLQKAEEAGAELQAELRGTREEKEELKDKLSEAHHQQETATAHLEQLHQDAERQEETLARAVQEKEALVRERAALEVRLQAVERDRQDLTEHVLGLRSAKEQLESNLFEAQQQNSVIQVTKGQLEVQIQTIIQAKEVIQGEVKCLKLELDAERTRAEQEWDAVARQLAQAEQEGQASLERQKVAHEEEVNRLQEKWEKERSWLQQELDKTLETLERERAELETKLREQQTEMEAIRAQREEERSQADSALYQMQLETEKERVSLLETLLRTQKELADASQQLERLRQDMKIQKLKEQETTGMLQAQLQETQQELKEAAQQHRDDLAAFQKDKLDLQKQVEDLMSQLVAHDDSQRLVKEEIEEKVKVAQECSRIQKELEKENASLALSLVEKEKRLLILQEADSVRQQELSSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRVAEQQLRASLWAQEAKATQLQLQLRSTESQLEALVAEQQPENQAQAQLASLCSVLQQALGSACESRPELRGGGDSAPTLWGPDPDQNGASRLFKRWSLPTALSPEAVALALQKLHQDVWKARQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGRQNSLESELRDLHETAASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVAEAQAQADAAAVLEEDLRTARSALKLKNEELESERERAQALQEQGELKVAQGKALQENLALLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRSVLEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHHKVESQQKMITELEGQREMQRVALTHLTLDLEERSQELQAQSSQLHELENHSTHLAKELQERDQEVTSQRQQIDELQKQQEQLAQALERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERSQELASQWQLVHERADDGKSPSKGQRGSLEHLKLILRDKEKEVECQQERIQELQGHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQHLQEAKEQGELREQVLQGQLEEAQRDLAQRDHELETLRQEKQQTQDQEESMKLKTSALQAALEQAHATLKERQGELEEHREQVRRLQEELEVEGRQVRALEEVLGDLRAESREHEKAVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLTEQEQELAALRAENQYSRRQEEAAVSQAEALQEALSKAQAALQEKEQSLLEQAELSHTLEASTAALQATLDTCQASARQLEEALRIREGEIQAQALQHHEVTQHLQQELCQKKEELRQLLEKAGARRSQENGIQEKQSLEQERQEETRRLLESLKELQLTVAQREEEILMLREASSPRHRALPAEKPALQPLPAQQELERLQTALRQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQASVLERESEQQRLQEELVLSRQALEEQQSGGPHSTSRADQGPKVGQGSQSGEVETEPSPGVEEKERLTQRLERLQQAVAELEVDRSKLQCHNAQLRTALEQVERERRKLKRDSVRASRAGSLEARETMTSSPTQQDGRGSQRGSSDSVLVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLNQSLTSPGPCLLHPSLDTTQNTHR", "length": 2414 }, "evidence": [ { "id": "A0A8V0ZC94", "url": "https://omabrowser.org/oma/group/A0A8V0ZC94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV73-1", "protein_name": "Centrosome-associated protein CEP250", "gene_name": "CEP250", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRSPGLNNMKPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSLTSPGPVLLHPSPSTTQAASR", 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24329:SF542", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24329:SF542", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046776654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFYFHCPPQLEGAAPFGAHSAGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGSSDQEGSKEAMAEVAPPVRNLNSPSPADQTRNKKESLEIQQSLSRAVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGSPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPTTGSPTPPAKPSPDSSQDKQLSPAKEHMEGEKSV", "length": 260, "header": "tr|A0A8V0ZDA2-1|A0A8V0ZDA2_CHICK Isoform 1 of Dorsal root ganglia homeobox protein OS=Gallus gallus OX=9031 GN=DRGX PE=4 SV=1 CANONICAL=A0A8V0ZDA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2/entry#A0A8V0ZCB7-1", "sequence": { "sequence": "MAVIGTLSGRGHASSLQPKGAAPFGAHSAGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGSSDQEGSKEAMAEVAPPVRNLNSPSPADQTRNKKESLEIQQSLSRAVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGSPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPTTGSPTPPAKPSPDSSQDKQLSPAKEHMEGEKSV", "length": 268, "header": "tr|A0A8V0ZCB7-1|A0A8V0ZDA2_CHICK Computationally mapped isoform of Dorsal root ganglia homeobox protein OS=Gallus gallus OX=9031 GN=DRGX PE=4 SV=1 CANONICAL=A0A8V0ZDA2-1" }, "locus": { "chromosome": "6", "start_pos": 19469833, "end_pos": 19455750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048799.1", "url": "https://www.ensembl.org/id/ENSGALT00010048799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028849.1", "url": "https://www.ensembl.org/id/ENSGALP00010028849.1" } ] } }, { "isoform_ac": "A0A8V0ZDA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2/entry#A0A8V0ZDA2-1", "sequence": { "sequence": "MFYFHCPPQLEGAAPFGAHSAGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGSSDQEGSKEAMAEVAPPVRNLNSPSPADQTRNKKESLEIQQSLSRAVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGSPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPTTGSPTPPAKPSPDSSQDKQLSPAKEHMEGEKSV", "length": 260, "header": "tr|A0A8V0ZDA2-1|A0A8V0ZDA2_CHICK Isoform 1 of Dorsal root ganglia homeobox protein OS=Gallus gallus OX=9031 GN=DRGX PE=4 SV=1 CANONICAL=A0A8V0ZDA2-1" }, "locus": { "chromosome": "6", "start_pos": 19470261, "end_pos": 19455750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048802.1", "url": "https://www.ensembl.org/id/ENSGALT00010048802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028851.1", "url": "https://www.ensembl.org/id/ENSGALP00010028851.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771373", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MZ61-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "Drgx", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPASKQAPPEGSQDKTSPTKEQSEGEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1X1M6-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "DRGX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASEQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPAAKPAPPDSSQDKTPLGKEQNEGEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6NNA5-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "DRGX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1BDA0-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "DRGX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNLNSPPPGDQARSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQTNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPSPVAKPAPLDGSQDKTPPSKEQSEHEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62798-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "Drgx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFALQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARGKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPGPASKQVPPEGSQDKPSPTKEQSEGEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BYH0-1", "protein_name": "Dorsal root ganglia homeobox protein", "gene_name": "Drgx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQTRSKKEALEAQQSLGRTVGPTGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPGPASKQAPPEGSQDKTSPTKEQSEGEKSV", "length": 263 }, "evidence": [ { "id": "A0A8V0ZDA2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 91, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA2" }, { "id": "PS50803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OAR", "eco_id": "ECO_0000259", "start_pos": 202, "end_pos": 215, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 144, 232 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCB8-1", "uniprot_ac": "A0A8V0ZCB8", "uniprot_id": "A0A8V0ZCB8_CHICK", "mass": { "chemical_mass": 73148.0, "monoisotopic_mass": 73148.0 }, "refseq": { "ac": "NP_001383400", "name": "coiled-coil domain-containing protein 174 isoform 2", "summary": "", "url": 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domain-containing protein 174 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001383400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383400" } ] }, { "name": "coiled-coil domain-containing protein 174", "type": "synonym", "evidence": [ { "id": "NP_001383400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383400" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.103328.1, SRR13267648.23591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383400" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC174", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB8", "locus": { "chromosome": "12", "start_pos": 11441426, "end_pos": 11428904, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021393", "url": "https://www.ensembl.org/id/ENSGALG00010021393" } ] } } ], "crossref": [ { "id": "A0A8V0ZCB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCB8", "database": "AlphaFoldDB", 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"A0A8V0ZQA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRRKKPLDVAASSLVDLKAELFRKQEEFKKEKLLKDAGIFAKPKPSNKKPSIWTKQNTGVAKRAEKDIEQKAEEDQTLDQSRKKLEEKAKLYEKMTKGDFPDEETEDLYLVDFTQKIIDKQREVQELYQNEAAIKTLEKETDDEEIEPEMEIPPPEDPDEEWVDYVDSLGRSRRCMKKDLPSILKMDQELQGKRLDPDGNTLLSEDMKRELQRQQWEKEEEEALRKPMGPIHYEDIRENEARQLGVGYFAFSRDQDLRHKQRATLDMLREQTLDQRTKREQLKEKRKAALESRLSKLRARKVKKLREEGLEEEAERLENGEVKDTTSPVEAEPEVPRPSRKVEVVIQERRDTKPGVPYVREWDKGKELMFGQWSKKQEELRDERDPEFAPPSDYFMGQKKDDGYSSQNLNSPETSPGKTEPEISENQKKLSVQASTHRAEVVPPSVQAYSNNVQGGLAPAEAAGSDAEDGSTSAETDSSDEQDGVPSAHPYICGAQNMPPSMPAYGYGPPHMMPPMPAYGYGAPHMMPPMQPYGYGAPHMMPPMQPYAYGTPNVPFSMHAYGYGTQDAPPPVQACDCSTQHAPPPMQACDCSAQDAPQSVQACDCSTQDAPPPEQTYSGDTQNQEPLYQSLDDMLSYYRQVT", "length": 643, "header": "tr|A0A8V0ZCB8-1|A0A8V0ZCB8_CHICK Isoform 1 of Coiled-coil domain containing 174 OS=Gallus gallus OX=9031 GN=CCDC174 PE=4 SV=1 CANONICAL=A0A8V0ZCB8-1" }, "isoforms": [ { 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"MDRRKKPLDVAASSLVDLKAELFRKQEEFKKEKLLKDAGIFAKPKPSNKKPSIWTKQNTGVAKRAEKDIEQKAEEDQTLDQSRKKLEEKAKLYEKMTKGDFPDEETEDLYLVDFTQKIIDKQREVQELYQNEAAIKTLEKETDDEEIEPEMEIPPPEDPDEEWVDYVDSLGRSRRCMKKDLPSILKMDQELQGKRLDPDGNTLLSEDMKRELQRQQWEKEEEEALRKPMGPIHYEDIRENEARQLGVGYFAFSRDQDLRHKQRATLDMLREQTLDQRTKREQLKEKRKAALESRLSKLRARKVKKLREEGLEEEAERLENGEVKDTTSPVEAEPEVPRPSRKVEVVIQERRDTKPGVPYVREWDKGKELMFGQWSKKQEELRDERDPEFAPPSDYFMGQKKDDGYSSQNLNSPETSPGKTEPEISENQKKLSVQASTHRAEVVPPSVQAYSNNVQGGLAPAEAAGSDAEDGSTSAETDSSDEQDGVPSAHPYICGAQNMPPSMPAYGYGPPHMMPPMPAYGYGAPHMMPPMQPYGYGAPHMMPPMQPYAYGTPNVPFSMHAYGYGTQDAPPPVQACDCSAQDAPQSVQACDCSTQDAPPPEQTYSGDTQNQEPLYQSLDDMLSYYRQVT", "length": 629, "header": "tr|A0A8V0ZQA1-1|A0A8V0ZQA1_CHICK Computationally mapped isoform of Coiled-coil domain containing 174 OS=Gallus gallus OX=9031 GN=CCDC174 PE=4 SV=1 CANONICAL=A0A8V0ZCB8-1" }, "locus": { "chromosome": "12", "start_pos": 11439987, "end_pos": 11428945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051824.1", "url": "https://www.ensembl.org/id/ENSGALT00010051824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030913.1", "url": "https://www.ensembl.org/id/ENSGALP00010030913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALHHRLLLPRCGGIPRGLGCAGRKLRVLGCERGTGRRRAEAARSVTGGPFCPGAGPGAAPACSLAATGVRSWSCMGSTISILVRQRNGTDSLHADSSTCVHNSYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMQTTYCEIDLDKGRREAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGYNTNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIVVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 659, "header": "tr|A0A8V0ZCD6-1|A0A8V0ZCD6_CHICK Isoform 1 of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF3 PE=1 SV=1 CANONICAL=A0A8V0ZCD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6/entry#A0A8V0ZCD6-1", "sequence": { "sequence": "MALHHRLLLPRCGGIPRGLGCAGRKLRVLGCERGTGRRRAEAARSVTGGPFCPGAGPGAAPACSLAATGVRSWSCMGSTISILVRQRNGTDSLHADSSTCVHNSYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMQTTYCEIDLDKGRREAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGYNTNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIVVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 659, "header": "tr|A0A8V0ZCD6-1|A0A8V0ZCD6_CHICK Isoform 1 of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF3 PE=1 SV=1 CANONICAL=A0A8V0ZCD6-1" }, "locus": { "chromosome": "6", "start_pos": 17483929, "end_pos": 17445308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048837.1", "url": "https://www.ensembl.org/id/ENSGALT00010048837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028869.1", "url": "https://www.ensembl.org/id/ENSGALP00010028869.1" } ] } }, { "isoform_ac": "A0A8V0ZJT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6/entry#A0A8V0ZJT7-1", "sequence": { "sequence": "MEFYFQLMRVSPKLYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMQTTYCEIDLDKGRREAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGYNTNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIVVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 569, "header": "tr|A0A8V0ZJT7-1|A0A8V0ZJT7_CHICK Computationally mapped isoform of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF3 PE=1 SV=1 CANONICAL=A0A8V0ZCD6-1" }, "locus": { "chromosome": "6", "start_pos": 17476164, "end_pos": 17445308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048836.1", "url": "https://www.ensembl.org/id/ENSGALT00010048836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028868.1", "url": "https://www.ensembl.org/id/ENSGALP00010028868.1" } ] } }, { "isoform_ac": "A0A8V0ZJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6/entry#A0A8V0ZJU2-1", "sequence": { "sequence": "MTEKKHTVLEKSSKFSFFKAKYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMQTTYCEIDLDKGRREAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGYNTNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIVVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID", "length": 576, "header": "tr|A0A8V0ZJU2-1|A0A8V0ZJU2_CHICK Computationally mapped isoform of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF3 PE=1 SV=1 CANONICAL=A0A8V0ZCD6-1" }, "locus": { "chromosome": "6", "start_pos": 17485563, "end_pos": 17445308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048841.1", "url": "https://www.ensembl.org/id/ENSGALT00010048841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028873.1", "url": "https://www.ensembl.org/id/ENSGALP00010028873.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDC2-1", "uniprot_ac": "A0A8V0ZDC2", "uniprot_id": "A0A8V0ZDC2_CHICK", "mass": { "chemical_mass": 48227.0, "monoisotopic_mass": 48227.0 }, "refseq": {}, "gene_names": [ { "name": "ACOT1L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ] } ], "protein_names": [ { "name": "ACOT1 thioesterase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACOT1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZDC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423222", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423222", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTNERWF", "url": "https://omabrowser.org/oma/group/CTNERWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDC2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVQVTVLPSPRCLFDDPVQIRVTGLLPQQAVTLRACLLDEAGELFQAHARYRAGGSGELDLTRCPALGGSYSGVEPMGLLWSLQSKTPYKRLAKRNVLTPFCVDLEVYEGHGDMSQLLGKCTHERYFLGEGVKRISVREGRLKATLFLPPGPGPFPGLIDLYGSGGGLVEYRASLLASRGFVTLALAYMAFEDLPAMPEILELDYFQEAIDFLQKQQQSCETFRVSYRTKAHYKVKDAGIGVLGLSKGADLALSMATFLPGIKAAVSISGSGFNSFIPLRGDGFTIPAHPYDLGRMKTNEESGFVDFSDILDDHRDPATWGSRIPVEKSLAKFLFLSGLDDKNWKSDLYCRDAVQRLHQCGQKVEFCSYSGAGHLLEPPYLPLCQSSIHKVLGVFVQWGGQWREHARAQEDAWHRIQAFFWKHLMNSDIPKSNL", "length": 435, "header": "tr|A0A8V0ZDC2-1|A0A8V0ZDC2_CHICK Isoform 1 of ACOT1 thioesterase OS=Gallus gallus OX=9031 GN=ACOT1L PE=1 SV=1 CANONICAL=A0A8V0ZDC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2/entry#A0A8V0ZCE1-1", "sequence": { "sequence": "MAVQVTVLPSPRCLFDDPVQIRVTGLLPQQAVTLRACLLDEAGELFQAHARYRAGGSGELDLTRCPALGGSYSGVEPMGLLWSLQSKTPYKRLAKRNVLTPFCVDLEVYEGHGDMSQLLGKCTHERYFLGEGVKRISVREGRLKATLFLPPGPGPFPGLIDLYGSGGGLVEYRASLLASRGFVTLALAYMAFEDLPAMPEILELDYFQEAIDFLQKQQQVKDAGIGVLGLSKGADLALSMATFLPGIKAAVSISGSGFNSFIPLRGDGFTIPAHPYDLGRMKTNEESGFVDFSDILDDHRDPATWGSRIPVEKSLAKFLFLSGLDDKNWKSDLYCRDAVQRLHQCGQKVEFCSYSGAGHLLEPPYLPLCQSSIHKVLGVFVQWGGQWREHARAQEDAWHRIQAFFWKHLMNSDIPKSNL", "length": 419, "header": "tr|A0A8V0ZCE1-1|A0A8V0ZDC2_CHICK Computationally mapped isoform of ACOT1 thioesterase OS=Gallus gallus OX=9031 GN=ACOT1L PE=1 SV=1 CANONICAL=A0A8V0ZDC2-1" }, "locus": { "chromosome": "5", "start_pos": 24667000, "end_pos": 24663971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048843.1", "url": "https://www.ensembl.org/id/ENSGALT00010048843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028874.1", "url": "https://www.ensembl.org/id/ENSGALP00010028874.1" } ] } }, { "isoform_ac": "A0A8V0ZDC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2/entry#A0A8V0ZDC2-1", "sequence": { "sequence": "MAVQVTVLPSPRCLFDDPVQIRVTGLLPQQAVTLRACLLDEAGELFQAHARYRAGGSGELDLTRCPALGGSYSGVEPMGLLWSLQSKTPYKRLAKRNVLTPFCVDLEVYEGHGDMSQLLGKCTHERYFLGEGVKRISVREGRLKATLFLPPGPGPFPGLIDLYGSGGGLVEYRASLLASRGFVTLALAYMAFEDLPAMPEILELDYFQEAIDFLQKQQQSCETFRVSYRTKAHYKVKDAGIGVLGLSKGADLALSMATFLPGIKAAVSISGSGFNSFIPLRGDGFTIPAHPYDLGRMKTNEESGFVDFSDILDDHRDPATWGSRIPVEKSLAKFLFLSGLDDKNWKSDLYCRDAVQRLHQCGQKVEFCSYSGAGHLLEPPYLPLCQSSIHKVLGVFVQWGGQWREHARAQEDAWHRIQAFFWKHLMNSDIPKSNL", "length": 435, "header": "tr|A0A8V0ZDC2-1|A0A8V0ZDC2_CHICK Isoform 1 of ACOT1 thioesterase OS=Gallus gallus OX=9031 GN=ACOT1L PE=1 SV=1 CANONICAL=A0A8V0ZDC2-1" }, "locus": { "chromosome": "5", "start_pos": 24667000, "end_pos": 24663971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048839.1", "url": "https://www.ensembl.org/id/ENSGALT00010048839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028871.1", "url": "https://www.ensembl.org/id/ENSGALP00010028871.1" } ] } }, { "isoform_ac": "A0A8V0ZDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2/entry#A0A8V0ZDC8-1", "sequence": { "sequence": "MAVQVTVLPSPRCLFDDPVQIRVTGLLPQQAVTLRACLLDEAGELFQAHARYRAGGSGELDLTRCPALGGSYSGVEPMGLLWSLQSKTPYKRLAKRNVLTPFCVDLEVYEGHGDMSQLLGKCTHERYFLGEGVKRISVREGRLKATLFLPPGPGPFPGLIDLYGSGGGLVEYRASLLASRGFVTLALAYMAFEDLPAMPEILELDYFQEAIDFLQKQQQVKDAGIGVLGLSKGADLALSMATFLPGIKAAVSISGSGFNSFIPLRGDGFTIPAHPYDLGRMKTNEESGFVDFSDILDDHRDPATWGSRIPVEKSLAKFLFLSGLDDKNWKSDLYCRDAVQRLHQCGQKVEFCSYSGAGHLLEPPYLPLCQSSIHKVLGRLWIS", "length": 383, "header": "tr|A0A8V0ZDC8-1|A0A8V0ZDC8_CHICK Computationally mapped isoform of Acyl-coenzyme A thioesterase 1 OS=Gallus gallus OX=9031 GN=ACOT1L PE=1 SV=1 CANONICAL=A0A8V0ZDC2-1" }, "locus": { "chromosome": "5", "start_pos": 24672341, "end_pos": 24663971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048847.1", "url": "https://www.ensembl.org/id/ENSGALT00010048847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028876.1", "url": "https://www.ensembl.org/id/ENSGALP00010028876.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423222", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423222", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "thiolester hydrolase activity", "id": "GO:0016790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ], "pmid": "" }, { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" }, { "id": "PF04775", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 140, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDC2" }, { "id": "PF08840", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAAT/Acyl-CoA thioester hydrolase C-terminal", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 426, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCI9-1", "uniprot_ac": "A0A8V0ZCI9", "uniprot_id": "A0A8V0ZCI9_CHICK", "mass": { "chemical_mass": 160666.0, "monoisotopic_mass": 160666.0 }, "refseq": {}, "gene_names": [ { "name": "MEGF6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ] } ], "protein_names": [ { "name": "Multiple EGF like domains 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEGF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9", "locus": { "chromosome": "21", "start_pos": 1020636, "end_pos": 984347, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021409", "url": "https://www.ensembl.org/id/ENSGALG00010021409" } ] } } ], "crossref": [ { "id": "419385", "url": "https://www.ncbi.nlm.nih.gov/gene/419385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCF5", "url": "https://www.orthodb.org/?gene=A0A8V0ZCF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZCI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI17", "url": "https://www.orthodb.org/?gene=A0A8V0ZI17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24043:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24043:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCTELRKQPGGWMCSTGDPQQQRCRGAAMEAPVLALILALWISPLAAGTELQPHMTAHRSGYRRLYGLQHRTAYRCCTGWAQRPGSTACLHHVDECQVHNGGCQHRCVNTFGSYYCECKPGFRLHADGRTCIALNSCAVNNGGCEHDCVQLTANQHQCRCRRQYRLREDGRRCAPWSPCAQRNGGCMQLCRDVQGAARCECRPGYRLGPDGRACQDVDECLAGLATCAHRCLNTHGSFMCACNPGYELGADSRQCYRIEMEIVSSCESGNGGCSHLCHHSSAGPICTCNSGYQLQDDQRTCTDINECEDGSHCCQQDCYNYPGGYECACHAGYRLRADGCACDDVDECSSNNGDCEHTCQNQVGSFQCGCPIGYKLDGDRRGCISVEDSVEALDARLPIIRPIPHVAILQDELTQLFSDDYEEEEEMEARGEHTLSETFVCLEDTFGPDCSLTCEDCQNGGTCNVEGTGCECPAGWSGLLCNQTCPPGTFGKNCSQLCLCQNGGTCEPTTGTCRCPPGVAGIHCEDGCPKGFFGKQCRKKCNCANRGRCHRIYGACLCDPGLYGRYCHLACPKWAFGPGCSEECLCVQPNTQHCDKRDGSCSCKPGYSGVHCETKCEPGRYGEGCKKKCSCPPDARCDHITGRCWKECPQGYHGENCDQECPAGRFGAGCLLLCSCGGAPCDAVSGRCVCAPGWTGHDCAQACPEGRWGLGCQELCPECANNGSCDPATGACVCPPGFTGSRCQDVCPPGWFGQDCQQSCSCGNEGHCHPVTGTCSCAPGWTGHDCRRGCAVGRWGPSCANVCECSSSTGSCDAVTGQCACDAGYTGSRCEERCPAGWFGLGCRRRCQCEHGATCDHVSGACTCAEGWRGTFCEHPCPDGFYGIECQHACNCQNGAHCDHITGQCHCHPGWTGPRCAHACPQGRFGEGCSQVCSCSNNATCDHITGRCLCTAGWMGPTCQQACPEGFYGTGCHQHCLCQNGGTCDPTTGHCICPMGWTGLACELACAEGHGDGCGQRCACLNGGVCNPQGQCQCPPGWSGSSCESPCPEGHFGAGCQERCDCGDKGLCNPITGTCQCPPGWRGRRCEKACLPGAFGKSCAERCACPPGAPCDHITGQCSCPPGFTGAACETPCPPGTFGERCAQRCRCVGPTQDCHPISGVCVCAPGHHGPDCELECPVGWYGPGCERPCECKNGARCERTTGTCHCPAGYIGADCSIVCPTGRYGTDCAQLCACGEGATCHHVTGDCLCPPGRVGPTCEQGCQPQQYGVGCLQPCSCLNGGLCNATDGSCSCGLGWTGKSCELECPAGSFGADCQLRCACRHNATCDPTTGACRCPPGRYGALCEHGCPPGFHGTDCQQHCDCAHGAACDPATGHCHCPVGLRGPRCQEGCEEGTYGEGCRQRCDCVGNAPCDRITGHCLCPPGKTGPRCDSECPVNRYGPDCALTCTCASSTQCSARTGRCHCHRGSMGSSCREAVPAQVPTRSPALQGMEHYVLPQPQGTAQLHKPAGGLVPKALE", "length": 1520, "header": "tr|A0A8V0ZCI9-1|A0A8V0ZCI9_CHICK Isoform 1 of Multiple EGF like domains 6 OS=Gallus gallus OX=9031 GN=MEGF6 PE=4 SV=1 CANONICAL=A0A8V0ZCI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9/entry#A0A8V0ZCF5-1", "sequence": { "sequence": "MRQEHFGMLLWCFGFLGSIPGAAGNHYRYQWRSCYPCYLGRAGYSVGHAEMRPDVDECQVHNGGCQHRCVNTFGSYYCECKPGFRLHADGRTCIALNSCAVNNGGCEHDCVQLTANQHQCRCRRQYRLREDGRRCAPWSPCAQRNGGCMQLCRDVQGAARCECRPGYRLGPDGRACQDVDECLAGLATCAHRCLNTHGSFMCACNPGYELGADSRQCYRIEMEIVSSCESGNGGCSHLCHHSSAGPICTCNSGYQLQDDQRTCTDINECEDGSHCCQQDCYNYPGGYECACHAGYRLRADGCACDDVDECSSNNGDCEHTCQNQVGSFQCGCPIGYKLDGDRRGCISVEDSVEALDARLPIIRPIPHVAILQDELTQLFSDDYEEEEEMEARGEHTLSETFVCLEDTFGPDCSLTCEDCQNGGTCNVEGTGCECPAGWSGLLCNQTCPPGTFGKNCSQLCLCQNGGTCEPTTGTCRCPPGVAGIHCEDGCPKGFFGKQCRKKCNCANRGRCHRIYGACLCDPGLYGRYCHLACPKWAFGPGCSEECLCVQPNTQHCDKRDGSCSCKPGYSGVHCETKCEPGRYGEGCKKKCSCPPDARCDHITGRCWKECPQGYHGENCDQECPAGRFGAGCLLLCSCGGAPCDAVSGRCVCAPGWTGHDCAQACPEGRWGLGCQELCPECANNGSCDPATGACVCPPGFTGSRCQDVCPPGWFGQDCQQSCSCGNEGHCHPVTGTCSCAPGWTGHDCRRGCAVGRWGPSCANVCECSSSTGSCDAVTGQCACDAGYTGSRCEERCPAGWFGLGCRRRCQCEHGATCDHVSGACTCAEGWRGTFCEHPCPDGFYGIECQHACNCQNGAHCDHITGQCHCHPGWTGPRCAHACPQGRFGEGCSQVCSCSNNATCDHITGRCLCTAGWMGPTCQQACPEGFYGTGCHQHCLCQNGGTCDPTTGHCICPMGWTGLACELACAEGHGDGCGQRCACLNGGVCNPQGQCQCPPGWSGSSCESPCPEGHFGAGCQERCDCGDKGLCNPITGTCQCPPGWRGRRCEKACLPGAFGKSCAERCACPPGAPCDHITGQCSCPPGFTGAACETPCPPGTFGERCAQRCRCVGPTQDCHPISGVCVCAPGHHGPDCELECPVGWYGPGCERPCECKNGARCERTTGTCHCPAGYIGADCSIVCPTGRYGTDCAQLCACGEGATCHHVTGDCLCPPGRVGPTCEQGCQPQQYGVGCLQPCSCLNGGLCNATDGSCSCGLGWTGKSCELECPAGSFGADCQLRCACRHNATCDPTTGACRCPPGRYGALCEHGCPPGFHGTDCQQHCDCAHGAACDPATGHCHCPVGLRGPRCQEAGCEEGTYGEGCRQRCDCVGNAPCDRITGHCLCPPGKTGPRCDSECPVNRYGPDCALTCTCASSTQCSARTGRCHCHRGSMGSSCREAVPAQVPTRSPALQGMEHYVLPQPQGTAQLHKPAGGLVPKALE", "length": 1482, "header": "tr|A0A8V0ZCF5-1|A0A8V0ZCI9_CHICK Computationally mapped isoform of Multiple EGF like domains 6 OS=Gallus gallus OX=9031 GN=MEGF6 PE=4 SV=1 CANONICAL=A0A8V0ZCI9-1" }, "locus": { "chromosome": "21", "start_pos": 1019943, "end_pos": 998662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051879.1", "url": "https://www.ensembl.org/id/ENSGALT00010051879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030952.1", "url": "https://www.ensembl.org/id/ENSGALP00010030952.1" } ] } }, { "isoform_ac": "A0A8V0ZCH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9/entry#A0A8V0ZCH1-1", "sequence": { "sequence": "MDCTELRKQPGGWMCSTGDPQQQRCRGAAMEAPVLALILALWISPLAAGTELQPHMTAHRSGYRRLYGLQHRTAYRCCTGWAQRPGSTACLHHVDECQVHNGGCQHRCVNTFGSYYCECKPGFRLHADGRTCIALNSCAVNNGGCEHDCVQLTANQHQCRCRRQYRLREDGRRCAPWSPCAQRNGGCMQLCRDVQGAARCECRPGYRLGPDGRACQDVDECLAGLATCAHRCLNTHGSFMCACNPGYELGADSRQCYRIEMEIVSSCESGNGGCSHLCHHSSAGPICTCNSGYQLQDDQRTCTDINECEDGSHCCQQDCYNYPGGYECACHAGYRLRADGCACDAVEDSVEALDARLPIIRPIPHVAILQDELTQLFSDDYEEEEEMEARGEHTLSETFVCLEDTFGPDCSLTCEDCQNGGTCNVEGTGCECPAGWSGLLCNQTCPPGTFGKNCSQLCLCQNGGTCEPTTGTCRCPPGVAGIHCEDGCPKGFFGKQCRKKCNCANRGRCHRIYGACLCDPGLYGRYCHLACPKWAFGPGCSEECLCVQPNTQHCDKRDGSCSCKPGYSGVHCETKCEPGRYGEGCKKKCSCPPDARCDHITGRCWKECPQGYHGENCDQECPAGRFGAGCLLLCSCGGAPCDAVSGRCVCAPGWTGHDCAQACPEGRWGLGCQELCPECANNGSCDPATGACVCPPGFTGSRCQDVCPPGWFGQDCQQSCSCGNEGHCHPVTGTCSCAPGWTGHDCRRGCAVGRWGPSCANVCECSSSTGSCDAVTGQCACDAGYTGSRCEERCPAGWFGLGCRRRCQCEHGATCDHVSGACTCAEGWRGTFCEHPCPDGFYGIECQHACNCQNGAHCDHITGQCHCHPGWTGPRCAHACPQGRFGEGCSQVCSCSNNATCDHITGRCLCTAGWMGPTCQQACPEGFYGTGCHQHCLCQNGGTCDPTTGHCICPMGWTGLACELACAEGHGDGCGQRCACLNGGVCNPQGQCQCPPGWSGSSCESPCPEGHFGAGCQERCDCGDKGLCNPITGTCQCPPGWRGRRCEKACLPGAFGKSCAERCACPPGAPCDHITGQCSCPPGFTGAACETPCPPGTFGERCAQRCRCVGPTQDCHPISGVCVCAPGHHGPDCELECPVGWYGPGCERPCECKNGARCERTTGTCHCPAGYIGADCSIVCPTGRYGTDCAQLCACGEGATCHHVTGDCLCPPGRVGPTCEQGCQPQQYGVGCLQPCSCLNGGLCNATDGSCSCGLGWTGKSCELECPAGSFGADCQLRCACRHNATCDPTTGACRCPPGRYGALCEHGCPPGFHGTDCQQHCDCAHGAACDPATGHCHCPVGLRGPRCQEGCEEGTYGEGCRQRCDCVGNAPCDRITGHCLCPPGKTGPRCDSECPVNRYGPDCALTCTCASSTQCSARTGRCHCHRGSMGSSCREAVPAQVPTRSPALQGMEHYVLPQPQGTAQLHKPAGGLVPKALE", "length": 1479, "header": "tr|A0A8V0ZCH1-1|A0A8V0ZCH1_CHICK Computationally mapped isoform of Multiple EGF like domains 6 OS=Gallus gallus OX=9031 GN=MEGF6 PE=4 SV=1 CANONICAL=A0A8V0ZCI9-1" }, "locus": { "chromosome": "21", "start_pos": 1019943, "end_pos": 985981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051899.1", "url": "https://www.ensembl.org/id/ENSGALT00010051899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030967.1", "url": "https://www.ensembl.org/id/ENSGALP00010030967.1" } ] } }, { "isoform_ac": "A0A8V0ZCI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9/entry#A0A8V0ZCI9-1", "sequence": { "sequence": "MDCTELRKQPGGWMCSTGDPQQQRCRGAAMEAPVLALILALWISPLAAGTELQPHMTAHRSGYRRLYGLQHRTAYRCCTGWAQRPGSTACLHHVDECQVHNGGCQHRCVNTFGSYYCECKPGFRLHADGRTCIALNSCAVNNGGCEHDCVQLTANQHQCRCRRQYRLREDGRRCAPWSPCAQRNGGCMQLCRDVQGAARCECRPGYRLGPDGRACQDVDECLAGLATCAHRCLNTHGSFMCACNPGYELGADSRQCYRIEMEIVSSCESGNGGCSHLCHHSSAGPICTCNSGYQLQDDQRTCTDINECEDGSHCCQQDCYNYPGGYECACHAGYRLRADGCACDDVDECSSNNGDCEHTCQNQVGSFQCGCPIGYKLDGDRRGCISVEDSVEALDARLPIIRPIPHVAILQDELTQLFSDDYEEEEEMEARGEHTLSETFVCLEDTFGPDCSLTCEDCQNGGTCNVEGTGCECPAGWSGLLCNQTCPPGTFGKNCSQLCLCQNGGTCEPTTGTCRCPPGVAGIHCEDGCPKGFFGKQCRKKCNCANRGRCHRIYGACLCDPGLYGRYCHLACPKWAFGPGCSEECLCVQPNTQHCDKRDGSCSCKPGYSGVHCETKCEPGRYGEGCKKKCSCPPDARCDHITGRCWKECPQGYHGENCDQECPAGRFGAGCLLLCSCGGAPCDAVSGRCVCAPGWTGHDCAQACPEGRWGLGCQELCPECANNGSCDPATGACVCPPGFTGSRCQDVCPPGWFGQDCQQSCSCGNEGHCHPVTGTCSCAPGWTGHDCRRGCAVGRWGPSCANVCECSSSTGSCDAVTGQCACDAGYTGSRCEERCPAGWFGLGCRRRCQCEHGATCDHVSGACTCAEGWRGTFCEHPCPDGFYGIECQHACNCQNGAHCDHITGQCHCHPGWTGPRCAHACPQGRFGEGCSQVCSCSNNATCDHITGRCLCTAGWMGPTCQQACPEGFYGTGCHQHCLCQNGGTCDPTTGHCICPMGWTGLACELACAEGHGDGCGQRCACLNGGVCNPQGQCQCPPGWSGSSCESPCPEGHFGAGCQERCDCGDKGLCNPITGTCQCPPGWRGRRCEKACLPGAFGKSCAERCACPPGAPCDHITGQCSCPPGFTGAACETPCPPGTFGERCAQRCRCVGPTQDCHPISGVCVCAPGHHGPDCELECPVGWYGPGCERPCECKNGARCERTTGTCHCPAGYIGADCSIVCPTGRYGTDCAQLCACGEGATCHHVTGDCLCPPGRVGPTCEQGCQPQQYGVGCLQPCSCLNGGLCNATDGSCSCGLGWTGKSCELECPAGSFGADCQLRCACRHNATCDPTTGACRCPPGRYGALCEHGCPPGFHGTDCQQHCDCAHGAACDPATGHCHCPVGLRGPRCQEGCEEGTYGEGCRQRCDCVGNAPCDRITGHCLCPPGKTGPRCDSECPVNRYGPDCALTCTCASSTQCSARTGRCHCHRGSMGSSCREAVPAQVPTRSPALQGMEHYVLPQPQGTAQLHKPAGGLVPKALE", "length": 1520, "header": "tr|A0A8V0ZCI9-1|A0A8V0ZCI9_CHICK Isoform 1 of Multiple EGF like domains 6 OS=Gallus gallus OX=9031 GN=MEGF6 PE=4 SV=1 CANONICAL=A0A8V0ZCI9-1" }, "locus": { "chromosome": "21", "start_pos": 1019943, "end_pos": 985981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051914.1", "url": "https://www.ensembl.org/id/ENSGALT00010051914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030982.1", "url": "https://www.ensembl.org/id/ENSGALP00010030982.1" } ] } }, { "isoform_ac": "A0A8V0ZI17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9/entry#A0A8V0ZI17-1", "sequence": { "sequence": "MRQEHFGMLLWCFGFLGSIPGAAGNHYRYQWRSCYPCYLGRAGYSVGHAEMRPDVDECQVHNGGCQHRCVNTFGSYYCECKPGFRLHADGRTCIALNSCAVNNGGCEHDCVQLTANQHQCRCRRQYRLREDGRRCAPWSPCAQRNGGCMQLCRDVQGAARCECRPGYRLGPDGRACQDVDECLAGLATCAHRCLNTHGSFMCACNPGYELGADSRQCYRIEMEIVSSCESGNGGCSHLCHHSSAGPICTCNSGYQLQDDQRTCTDVDECSSNNGDCEHTCQNQVGSFQCGCPIGYKLDGDRRGCISVEDSVEALDARLPIIRPIPHVAILQDELTQLFSDDYEEEEEMEARGEHTLSETFVCLEDTFGPDCSLTCEDCQNGGTCNVEGTGCECPAGWSGLLCNQTCPPGTFGKNCSQLCLCQNGGTCEPTTGTCRCPPGVAGIHCEDGCPKGFFGKQCRKKCNCANRGRCHRIYGACLCDPGLYGRYCHLACPKWAFGPGCSEECLCVQPNTQHCDKRDGSCSCKPGYSGVHCETKCEPGRYGEGCKKKCSCPPDARCDHITGRCWKECPQGYHGENCDQECPAGRFGAGCLLLCSCGGAPCDAVSGRCVCAPGWTGHDCAQACPEGRWGLGCQELCPECANNGSCDPATGACVCPPGFTGSRCQDVCPPGWFGQDCQQSCSCGNEGHCHPVTGTCSCAPGWTGHDCRRGCAVGRWGPSCANVCECSSSTGSCDAVTGQCACDAGYTGSRCEERCPAGWFGLGCRRRCQCEHGATCDHVSGACTCAEGWRGTFCEHPCPDGFYGIECQHACNCQNGAHCDHITGQCHCHPGWTGPRCAHACPQGRFGEGCSQVCSCSNNATCDHITGRCLCTAGWMGPTCQQACPEGFYGTGCHQHCLCQNGGTCDPTTGHCICPMGWTGLACELACAEGHGDGCGQRCACLNGGVCNPQGQCQCPPGWSGSSCESPCPEGHFGAGCQERCDCGDKGLCNPITGTCQCPPGWRGRRCEKACLPGAFGKSCAERCACPPGAPCDHITGQCSCPPGFTGAACETPCPPGTFGERCAQRCRCVGPTQDCHPISGVCVCAPGHHGPDCELECPVGWYGPGCERPCECKNGARCERTTGTCHCPAGYIGADCSIVCPTGRYGTDCAQLCACGEGATCHHVTGDCLCPPGRVGPTCEQGCQPQQYGVGCLQPCSCLNGGLCNATDGSCSCGLGWTGKSCELECPAGSFGADCQLRCACRHNATCDPTTGACRCPPGRYGALCEHGCPPGFHGTDCQQHCDCAHGAACDPATGHCHCPVGLRGPRCQEGCEEGTYGEGCRQRCDCVGNAPCDRITGHCLCPPGKTGPRCDSECPVNRYGPDCALTCTCASSTQCSARTGRCHCHRGSMGSSCREAVPAQVPTRSPALQGMEHYVLPQPQGTAQLHKPAGGLVPKALE", "length": 1440, "header": "tr|A0A8V0ZI17-1|A0A8V0ZI17_CHICK Computationally mapped isoform of Multiple EGF like domains 6 OS=Gallus gallus OX=9031 GN=MEGF6 PE=4 SV=1 CANONICAL=A0A8V0ZCI9-1" }, "locus": { "chromosome": "21", "start_pos": 1019943, "end_pos": 998662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051891.1", "url": "https://www.ensembl.org/id/ENSGALT00010051891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030959.1", "url": "https://www.ensembl.org/id/ENSGALP00010030959.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1153, "start_aa": "Thr", "end_pos": 1153, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1153", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1259, "start_aa": "Thr", "end_pos": 1259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1259", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1286, "end_pos": 1288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1325, "end_pos": 1327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCI9" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 133, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1153, 1259 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1286, "end_pos": 1288 }, { "start_pos": 1325, "end_pos": 1327 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 939, "end_pos": 941 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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[], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3", "locus": { "chromosome": "9", "start_pos": 17210859, "end_pos": 17230412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018255", "url": "https://www.ensembl.org/id/ENSGALG00010018255" } ] } } ], "crossref": [ { "id": "A0A8V0ZCG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10465:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10465:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013419", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013419", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAAVSPLKHFVLAKKTITAIFEQLLDYVTEGAAFVEATYRNPELEHVATEDELAEIQAYKKKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKSKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTVRRQHMERCLTFLVDELKVIDPVEARNRIFFVSAKEVLSARRQKAQGMPESGGALAEGFQTRFQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQIIDTVKNIMDAINVAAAEKRVLSMEEREDQKDRLDFVRNQLNILTEDTKEKIKRVTEEVENKVSSAMTDEICRLSVLVDEFYSDFHPSPQVLKLYKTELNKHIEDGLGKNLADRCSSEVNESMHQSQQEIIENLKPLLPSGAQNQLHLLIPCRKFDLSYDLNCHSLCADFQEDIMFHFSLGWTSLVNRFLGPKHAQRVLLGLADPNLQIPRPLATTPSAASLPAATPENTSPDDFMVPLVMSLASLTSRTSMSIIVVGGVIWKTVGWKLISLSLSMYGLLYLYERLTWTTKAKERAFKQQFVNYATEKLQMIVSLTSANCSHQVQQEMATTFARLCQQVDVTQKNLEKEIARLSKEIDQLENIQSHSKQLRNKAIHLENELDRFTKHFLQKSK", "length": 704, "header": "tr|A0A8V0ZCG3-1|A0A8V0ZCG3_CHICK Isoform 1 of Mitofusin 1 OS=Gallus gallus OX=9031 GN=MFN1 PE=1 SV=1 CANONICAL=A0A8V0ZCG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3/entry#A0A8V0ZCF8-1", "sequence": { "sequence": "MAEAAVSPLKHFVLAKKTITAIFEQLLDYVTEGAAFVEATYRNPELEHVATEDELAEIQAYKKKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKSKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLTFLVDELKVIDPVEARNRIFFVSAKEVLSARRQKAQGMPESGGALAEGFQTRFQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQIIDTVKNIMDAINVAAAEKRVLSMEEREDQKDRLDFVRNQLNILTEDTKEKIKRVTEEVENKVSSAMTDEICRLSVLVDEFYSDFHPSPQVLKLYKTELNKHIEDGLGKNLADRCSSEVNESMHQSQQEIIENLKPLLPSGAQNQLHLLIPCRKFDLSYDLNCHSLCADFQEDIMFHFSLGWTSLVNRFLGPKHAQRVLLGLADPNLQIWKTVGWKLISLSLSMYGLLYLYERLTWTTKAKERAFKQQFVNYATEKLQMIVSLTSANCSHQVQQEMATTFARLCQQVDVTQKNLEKEIARLSKEIDQLENIQSHSKQLRNKAIHLENELDRFTKHFLQKSK", "length": 688, "header": "tr|A0A8V0ZCF8-1|A0A8V0ZCG3_CHICK Computationally mapped isoform of Mitofusin 1 OS=Gallus gallus OX=9031 GN=MFN1 PE=1 SV=1 CANONICAL=A0A8V0ZCG3-1" }, "locus": { "chromosome": "9", "start_pos": 17229908, "end_pos": 17212353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044071.1", "url": "https://www.ensembl.org/id/ENSGALT00010044071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026195.1", "url": "https://www.ensembl.org/id/ENSGALP00010026195.1" } ] } }, { "isoform_ac": "A0A8V0ZCG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3/entry#A0A8V0ZCG3-1", "sequence": { "sequence": "MAEAAVSPLKHFVLAKKTITAIFEQLLDYVTEGAAFVEATYRNPELEHVATEDELAEIQAYKKKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKSKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTVRRQHMERCLTFLVDELKVIDPVEARNRIFFVSAKEVLSARRQKAQGMPESGGALAEGFQTRFQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQIIDTVKNIMDAINVAAAEKRVLSMEEREDQKDRLDFVRNQLNILTEDTKEKIKRVTEEVENKVSSAMTDEICRLSVLVDEFYSDFHPSPQVLKLYKTELNKHIEDGLGKNLADRCSSEVNESMHQSQQEIIENLKPLLPSGAQNQLHLLIPCRKFDLSYDLNCHSLCADFQEDIMFHFSLGWTSLVNRFLGPKHAQRVLLGLADPNLQIPRPLATTPSAASLPAATPENTSPDDFMVPLVMSLASLTSRTSMSIIVVGGVIWKTVGWKLISLSLSMYGLLYLYERLTWTTKAKERAFKQQFVNYATEKLQMIVSLTSANCSHQVQQEMATTFARLCQQVDVTQKNLEKEIARLSKEIDQLENIQSHSKQLRNKAIHLENELDRFTKHFLQKSK", "length": 704, "header": "tr|A0A8V0ZCG3-1|A0A8V0ZCG3_CHICK Isoform 1 of Mitofusin 1 OS=Gallus gallus OX=9031 GN=MFN1 PE=1 SV=1 CANONICAL=A0A8V0ZCG3-1" }, "locus": { "chromosome": "9", "start_pos": 17229908, "end_pos": 17212353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044078.1", "url": "https://www.ensembl.org/id/ENSGALT00010044078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026200.1", "url": "https://www.ensembl.org/id/ENSGALP00010026200.1" } ] } }, { "isoform_ac": "A0A8V0ZCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3/entry#A0A8V0ZCG8-1", "sequence": { "sequence": "MAEAAVSPLKHFVLAKKTITAIFEQLLDYVTEGAAFVEATYRNPELEHVATEDELAEIQAYKKKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKSKCALLRDDLVLVDRSLTEECMTVSDEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLTFLVDELKVIDPVEARNRIFFVSAKEVLSARRQKAQGMPESGGALAEGFQTRFQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQIIDTVKNIMDAINVAAAEKRVLSMEEREDQKDRLDFVRNQLNILTEDTKEKIKRVTEEVENKVSNDFFLCVLVCLFVCLFEKSFWILVVLKAGQHCKDSTWEYTVRLSVLTHPHYSVLFLENLKPLLPSGAQNQLHLLIPCRKFDLSYDLNCHSLCADFQEDIMFHFSLGWTSLVNRFLGPKHAQRVLLGLADPNLQIPRPLATTPSAASLPAATPENTSPDDFMVPLVMSLASLTSRTSMSIIVVGGVIWKTVGWKLISLSLSMYGLLYLYERLTWTTKAKERAFKQQFVNYATEKLQMIVSLTSANCSHQVQQEMATTFARLCQQVDVTQKNLEKEIARLSKEIDQLENIQSHSKQLRNKAIHLENELDRFTKHFLQKSK", "length": 704, "header": "tr|A0A8V0ZCG8-1|A0A8V0ZCG8_CHICK Computationally mapped isoform of Mitofusin 1 OS=Gallus gallus OX=9031 GN=MFN1 PE=1 SV=1 CANONICAL=A0A8V0ZCG3-1" }, "locus": { "chromosome": "9", "start_pos": 17229908, "end_pos": 17212353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044087.1", "url": "https://www.ensembl.org/id/ENSGALT00010044087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026206.1", "url": "https://www.ensembl.org/id/ENSGALP00010026206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" }, { "id": "R-GGA-9013419", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013419", "resource": "Reactome", "description": "RHOT2 GTPase cycle" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "outer mitochondrial membrane protein complex", "id": "GO:0098799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098799", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial membrane potential", "id": "GO:0010918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010918", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "GTP metabolic process", "id": "GO:0046039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG3" }, { "id": "PS51718", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51718" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynamin-type G", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 216, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 }, { "start_pos": 540, "end_pos": 542 }, { "start_pos": 630, "end_pos": 632 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000331.1. On or before May 4, 2022 this sequence version replaced XP_046759454.1, XP_046787718.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001392767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392767" } ] }, { "annotation": "The role and function of GNK1 in smooth muscle cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001392767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392767" }, { "database": "PubMed", "id": "19057650", "url": "https://glygen.org/publication/PubMed/19057650" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GKN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2", "locus": { "chromosome": "22", "start_pos": 298680, "end_pos": 302962, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020264", "url": "https://www.ensembl.org/id/ENSGALG00010020264" } ] } } ], "crossref": [ { "id": "A0A8V0ZCH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "101751070", "url": "https://www.ncbi.nlm.nih.gov/gene/101751070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GNQIFYN", "url": "https://omabrowser.org/oma/group/GNQIFYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001392767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFTIVATVLLGLVLTPALSQFQYQDVKVNRRQYPRTITINVGLGFQTLTVNRNALVAIIEANSAENAWTTVWNYGTGYIATKLVREGVCYVSPMDRVVMPALDSIAVLAEQTNNVKGESVLPRSIRYVVSRRQARELRTYGNDIFALCSGLPTFIAFEESQPEGGNQIFYNQDACYRLDVLNLLGIEYCRAGKV", "length": 195, "header": "tr|A0A8V0ZCH2-1|A0A8V0ZCH2_CHICK Isoform 1 of Gastrokine 1 OS=Gallus gallus OX=9031 GN=GKN1 PE=4 SV=1 CANONICAL=A0A8V0ZCH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2/entry#A0A8V0ZCH2-1", "sequence": { "sequence": "MKFTIVATVLLGLVLTPALSQFQYQDVKVNRRQYPRTITINVGLGFQTLTVNRNALVAIIEANSAENAWTTVWNYGTGYIATKLVREGVCYVSPMDRVVMPALDSIAVLAEQTNNVKGESVLPRSIRYVVSRRQARELRTYGNDIFALCSGLPTFIAFEESQPEGGNQIFYNQDACYRLDVLNLLGIEYCRAGKV", "length": 195, "header": "tr|A0A8V0ZCH2-1|A0A8V0ZCH2_CHICK Isoform 1 of Gastrokine 1 OS=Gallus gallus OX=9031 GN=GKN1 PE=4 SV=1 CANONICAL=A0A8V0ZCH2-1" }, "locus": { "chromosome": "22", "start_pos": 302930, "end_pos": 298852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048902.1", "url": "https://www.ensembl.org/id/ENSGALT00010048902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028905.1", "url": "https://www.ensembl.org/id/ENSGALP00010028905.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Biochemical properties of gastrokine-1 purified from chicken gizzard smooth muscle.", "journal": "PloS one", "date": "2008", "authors": "Hnia Karim, Notarnicola C\u00e9cile, de Santa Barbara Pascal, Hugon G\u00e9rald, Rivier Fran\u00e7ois, Laoudj-Chenivesse Dalila, Mornet Dominique", "evidence": [ { "database": "RefSeq", "id": "NP_001392767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001392767" } ], "reference": [ { "type": "PubMed", "id": "19057650", "url": "https://glygen.org/publication/PubMed/19057650" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH2" }, { "id": "PS50869", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50869" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRICHOS", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 157, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCH4-1", "uniprot_ac": "A0A8V0ZCH4", "uniprot_id": "A0A8V0ZCH4_CHICK", "mass": { "chemical_mass": 76627.0, "monoisotopic_mass": 76627.0 }, "refseq": { "ac": "XP_015139294", "name": "kanadaptin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139294" }, "gene_names": [ { "name": "SLC4A1AP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4" } ] }, { "name": "SLC4A1AP", "type": "synonym", "evidence": [ { "id": "XP_015139294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139294" } ] } ], "protein_names": [ { "name": "Solute carrier family 4 member 1 adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4/entry#names_and_taxonomy" } ] }, { "name": "kanadaptin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139294" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139294.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139294" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC4A1AP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4", "locus": { "chromosome": "3", "start_pos": 27474915, "end_pos": 27492014, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020080", "url": "https://www.ensembl.org/id/ENSGALG00010020080" } ] } } ], "crossref": [ { "id": "A0A8V0ZCH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421420", "url": "https://www.ncbi.nlm.nih.gov/gene/421420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421420", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421420", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQAIWTF", "url": "https://omabrowser.org/oma/group/QQAIWTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139294", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAMETEAEPGEFKRPSRPLPAPQSAEPGPAPSPGPAPPRPAASAPAPRYEEPPWGSRPPADAGYGLEVLKGGVLLGSVRLEGGSWFLVGRLPGCALALEHPSVSRHHAVLQYRGRSADGPDADAGFYVYDLGSTHGTFLNKARVPPRTYCRVRVGHGLRFGGSSRLFLLQGPEEDQESESELTMTQLKALRKQQQAKLEKTMLGEDSDEEDEKEERGSESSQNVDMSCSWGMGEDAEEDEAEENPIAIEFQDVQDAFYMKDPRKALQGFFDREGEELEYEYDDRGHNSWLCRVKLPVDDALGKQLVAEVLHSGKKKEAMIQCALEACRLLDARGVLRQEAVSRKRKSKNWEDEDFYDSDDDTFLDRTGAVEKKRLNRMKKAGKIEEKPETYDSLVAKLKEAENELSEITEKLKASGRGQSQPAAQDSLDEFMTEIKSGSTLDSVTRKKLHLRSFELKKEQQRLKGLIKLVKPTELPELKPPTGSYSLEANSKSKKITLPLFGAMKGGSKFKLKTGSLGKLPDKRPHIPESLLKMKDDGPEEEEEEEEEEIEEEQKVDAVSSRTSDVEMKATVEEETGKETNGPNGSTCNNEDLESLQDGVSFQPEPKILRNKSQMGPSQEKSQASEAVCKESRETSEEVKKSNTSSKLQQPFFSSQYPDDDPDYCIWIPPADQSGDGKTHLNDKYGY", "length": 689, "header": "tr|A0A8V0ZCH4-1|A0A8V0ZCH4_CHICK Isoform 1 of Solute carrier family 4 member 1 adaptor protein OS=Gallus gallus OX=9031 GN=SLC4A1AP PE=1 SV=1 CANONICAL=A0A8V0ZCH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4/entry#A0A8V0ZCH4-1", "sequence": { "sequence": "MAEAMETEAEPGEFKRPSRPLPAPQSAEPGPAPSPGPAPPRPAASAPAPRYEEPPWGSRPPADAGYGLEVLKGGVLLGSVRLEGGSWFLVGRLPGCALALEHPSVSRHHAVLQYRGRSADGPDADAGFYVYDLGSTHGTFLNKARVPPRTYCRVRVGHGLRFGGSSRLFLLQGPEEDQESESELTMTQLKALRKQQQAKLEKTMLGEDSDEEDEKEERGSESSQNVDMSCSWGMGEDAEEDEAEENPIAIEFQDVQDAFYMKDPRKALQGFFDREGEELEYEYDDRGHNSWLCRVKLPVDDALGKQLVAEVLHSGKKKEAMIQCALEACRLLDARGVLRQEAVSRKRKSKNWEDEDFYDSDDDTFLDRTGAVEKKRLNRMKKAGKIEEKPETYDSLVAKLKEAENELSEITEKLKASGRGQSQPAAQDSLDEFMTEIKSGSTLDSVTRKKLHLRSFELKKEQQRLKGLIKLVKPTELPELKPPTGSYSLEANSKSKKITLPLFGAMKGGSKFKLKTGSLGKLPDKRPHIPESLLKMKDDGPEEEEEEEEEEIEEEQKVDAVSSRTSDVEMKATVEEETGKETNGPNGSTCNNEDLESLQDGVSFQPEPKILRNKSQMGPSQEKSQASEAVCKESRETSEEVKKSNTSSKLQQPFFSSQYPDDDPDYCIWIPPADQSGDGKTHLNDKYGY", "length": 689, "header": "tr|A0A8V0ZCH4-1|A0A8V0ZCH4_CHICK Isoform 1 of Solute carrier family 4 member 1 adaptor protein OS=Gallus gallus OX=9031 GN=SLC4A1AP PE=1 SV=1 CANONICAL=A0A8V0ZCH4-1" }, "locus": { "chromosome": "3", "start_pos": 27491815, "end_pos": 27475954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048512.1", "url": "https://www.ensembl.org/id/ENSGALT00010048512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028606.1", "url": "https://www.ensembl.org/id/ENSGALP00010028606.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421420", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421420", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1K0-1", "protein_name": "Solute carrier family 4 member 1 adaptor protein", "gene_name": "Slc4a1ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADATSQLEAPAPQDVSSEFKKPVLPVPPAVRSKAPASSPSVPEDVKKECSTAQLDSGCGEPEVSPPQPDSEETGGPPVEQLRSPRVAPASGGPTRAPPYQEPSWGSPATAPYSLETLKGGTILGTRTLKDTSYCLFGRLASCDICLEHPSVSRYHAVLQHRGSDPSGDSEDQGQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVIRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQALLEKKMLGEDSDEEDEADTTAGKRNTSGQDEEMGCTWGMGEDAVEDEAEENPIALEFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSKVQSESSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEKAKEEHEEGVEDGGVRLSQGPEPEPEAAGEHPGAPPEPSCSKETKSHEKHSHMEQSKGYQEMGKIMPSREDPSAAPENECKKDRDELKKKKSGPGKFPPILSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "length": 738 }, "evidence": [ { "id": "A0A8V0ZCH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E2QCZ5-1", "protein_name": "FHA domain-containing protein", "gene_name": "Dmel\\CG7706", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNEFKVPAPLPKPKVIITEKPRSEVPAEPPPPPLKIPKTPKSSPAAVCPYKVPKWSAPPAENQIYSFEVLKSGQIIDTVHQLQQQAVWTFGRLPENDVPAAHPTISRFHVVLQYKPKAPPKPETAKEDDEMEEEDEEPKNDQPEGWYIYDMGSTHGTFLNKQRVPPKVYIRMRVGHMLKLGGSTRVYILQGPGEDEEPESELSVTELRQKREKELADAAVERELRLLEAEERERNEGVSWGMGDDADEETDLSHNPYASTNNEELFFDDPKKTLRGFFEREGLNLEYKCDELSTGSFVCRVELPLDDSNGRPIIVEVNHKGRKKDCVVQCALEACRTLDRHGVLRQANQEAQKRKQLKNRDSDDEDEFWDRTGDVARKKQRKDNAGVSVTLTYEDLLKQEIDLNMEMEKVEQEISTYQQNEKKLKELAAKQQAEGDDLDNFMDMLTKDVEQLDKTEIKKLRLEQQRIKGEQQKVERLLKIAKPTALPFTTSLAAGSKESAAQEGGAAKKKQLPMIGKRNQFSKFKVVKASPSTQTMTQSNAFASDEEEVEEEEVKEKVKEKEAEVDNLEKEETEPESTTKPSTPENDSLKETKLPAQPEESKPTVAKTEVLKPENVRSTKVSTEAPPAPSHTVASTNPDEDMSTPVEDSSAPAEDITARANDTSEPEEAQKKRRQRQRQRNKQRQDVDMDLDELAEHEDTEKYAKWVPPTNQSGDGITHLNEKFGY", "length": 726 }, "evidence": [ { "id": "A0A8V0ZCH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCH4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E7F3T1-1", "protein_name": "Kanadaptin isoform X1", "gene_name": "slc4a1ap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFDGSELTENIPTETMKTEKSQDPENGKICDSKQDITSTNETADDPFKKPVLTPSLAVKKSLGPSKKPTEEVSSSVSENTDADHDTKHLLSTAKAKDTKIDPSDHPPSERLKEPRVQPKSKDIRPKIPPAGKFPPLPYTEPPWGAVPDINYSFELLKNGAILDTVPLTHRSYFVVGRLPVCDVSLEHPSISRYHAVVQYRGRAGQEGVVGEERGFYAYDLGSTHGTFINKNKIPPKTYIRLRVGHVLKFGGSTRLFILQGPEFDEEAESEMTVTELRERARKQREELERRMMGDGSDEEEEKEESETSASKNTSEDAGCSWGMAEEAAPEEDDNEENPFATEFQEDQEAAYLKDPKKALQGFYDREGEELEFEYEDKAHGTWLCRIKLPVDDAVGRQLVAEVTHTGKKKEAAVQCCLEACRILEARGLLRQEAVSRKRKKKNWEDDDFYDSDDDTFLDRTGVVEKKRTERMKKAGKIQERPDTYESLLAKLADVEKELADTEKKLNLSGKGGSGSSTEDPLDAFMTAVRSEVALDGVERKKLHLHIADLKKEGQRLSRLVELAKPTQLPSLLSSGSHTQSSDSDKPKKLSLPMFGAMKGGSKFKLKTGTIGNLPPKRTSLPPELFTMKEMPPGGEEEVEEEENSEAEDVVTDGDMEVIQSVETAISEHSADSAESQTQQPKEEHEDQPAKTVISPKKDDPSPKGVNNKASNVQNPKTCAKKKVIGPSKPPVTMSKQYPEDDPDYCVWVPPSGQTGDGRTHLNDKYGY", "length": 768 }, "evidence": [ { "id": "A0A8V0ZCH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PX68-1", "protein_name": "Solute carrier family 4 (anion exchanger), member 1, adaptor protein", "gene_name": "Slc4a1ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPTPQLDAPAPQEVSSEFKKPVLPVPSAVRGKAPASSPSVSEDVKKECLAAQLDSGCEEPEVPPPQPDSQETGGPPVEQLRSPRVAPASGGPTRAPPYREPSWGSPATAPYSLETLKGGTILGTRTLKDTSCCFFGRLASCDICLEHPSVSRYHAVLQHRGADPSGDSEGHEQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVMRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEANTTEGKSSRSGQDDELGCTWGMGEDAVEDEAEENPIALDFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMVQCSLEACRVLDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNRMKKAGKLDEKPETFESLVAKLNDAERELAEISERLKASSKVLSEPSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEEEKVKEEHEERVEDGGVRLLQEPELELEAAVEHPSAPSEPSCSKETKSHESISQLSQVEQSKDYQEMGKIVSSCEDPSAAPANEYKQDRDEPKKKKSPGPGKFPPILSSKYPEDDPDYCIWVPPEGQSGDGRTHLNDKYGY", "length": 744 }, "evidence": [ { "id": "A0A8V0ZCH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWU0-2", "protein_name": "Kanadaptin", "gene_name": "SLC4A1AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADILSQSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPPPQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "length": 742 }, "evidence": [ { "id": "A0A8V0ZCH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCH4" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 146, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 586, "end_pos": 588 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 645, "end_pos": 647 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDZ6-1", "uniprot_ac": "A0A8V0ZDZ6", "uniprot_id": "A0A8V0ZDZ6_CHICK", "mass": { "chemical_mass": 85552.0, "monoisotopic_mass": 85552.0 }, "refseq": {}, "gene_names": [ { "name": "SEMA4B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ] } ], "protein_names": [ { "name": "Semaphorin 4B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEMA4B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6", "locus": { "chromosome": "10", "start_pos": 20070695, "end_pos": 20057833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020293", "url": "https://www.ensembl.org/id/ENSGALG00010020293" } ] } } ], "crossref": [ { "id": "A0A8V0ZDZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVLCSGSCYARPWGLRVLLTVLCAGARDGQPRISRVLAGRAPSPCRAVPGRCPWPCARSDIGDSAERVVQRFEVPGVSNYTALLLSPDGGTLYLGAREVLFAVNTSHFQHGVLARRLPWGADEEKKRQCVFKGKDPQRDCHNYIKMLLQLNSTHLYTCGTCAFSPTCAYINVQHFTLERDALGRVLLEDGKGRCPFDPEYRSTAVMVDGELYAGTVSNFQGNEPTIYRSQESRISLKTENSLSWLQDPVFVGSAFLQESLPAGNPDGDDDKVYFFFSETGKEFDYFENTIVSRIARVCKGDQGGERVLQRRWTTFLKAQLLCSHPEDGFPFNVLQDVFVLTPGEQRWRETLFYGVFTSQWNKGGLGSSAVCAFPMHSVQKAFGGLYKEVNRETQQWYTDTSPVPEPRPGTCITSHTRHLKINSSLQMPDRVLNFVKDHFLMDSPVRSQPLLLQSRLRYQQIGVHRVQGLRGTYDVLFLGTDDGRLHKAVRVNHRVHIIEEIRLFPTGQPILQLLLDHEQGLVYAASYTAVAQVPFSNCSLYRSCGECVLARDPFCAWSHGACRSTAPHPPAHPQLWAQDIEGAETERLCQPANVSQPRPRVLLPPASGTPCQRIQLPPNAVQPLPCRLLSNLASRRWLHNGTPVNASYLVLPEGALILVGSPERAGTYECWSLEEGFRKLMASYCVAVQEPGGRGFTAPETVSTSRSTSAVGSIAARLDGKTYWTEFLVMSGLFAAAMLVLILFLLHRHCDGVKALVEPGGRRPAPEGAP", "length": 771, "header": "tr|A0A8V0ZDZ6-1|A0A8V0ZDZ6_CHICK Isoform 1 of Semaphorin 4B OS=Gallus gallus OX=9031 GN=SEMA4B PE=3 SV=1 CANONICAL=A0A8V0ZDZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6/entry#A0A8V0ZCK8-1", "sequence": { "sequence": "MVPRPALPVLAHSVLAALLLSAAQEPVPRVSLPYDSAERVVQRFEVPGVSNYTALLLSPDGGTLYLGAREVLFAVNTSHFQHGVLARRLPWGADEEKKRQCVFKGKDPQRDCHNYIKMLLQLNSTHLYTCGTCAFSPTCAYINVQHFTLERDALGRVLLEDGKGRCPFDPEYRSTAVMVDGELYAGTVSNFQGNEPTIYRSQESRISLKTENSLSWLQDPVFVGSAFLQESLPAGNPDGDDDKVYFFFSETGKEFDYFENTIVSRIARVCKGDQGGERVLQRRWTTFLKAQLLCSHPEDGFPFNVLQDVFVLTPGEQRWRETLFYGVFTSQWNKGGLGSSAVCAFPMHSVQKAFGGLYKEVNRETQQWYTDTSPVPEPRPGTCITSHTRHLKINSSLQMPDRVLNFVKDHFLMDSPVRSQPLLLQSRLRYQQIGVHRVQGLRGTYDVLFLGTDDGRLHKAVRVNHRVHIIEEIRLFPTGQPILQLLLDHEQGLVYAASYTAVAQVPFSNCSLYRSCGECVLARDPFCAWSHGACRSTAPHPPAHPQLWAQDIEGAETERLCQPANVSQPRPRVLLPPASGTPCQRIQLPPNAVQPLPCRLLSNLASRRWLHNGTPVNASYLVLPEGALILVGSPERAGTYECWSLEEGFRKLMASYCVAVQEPGGRGFTAPETVSTSRSTSAVGSIAARLDGKTYWTEFLVMSGLFAAAMLVLILFLLHRHCDGVKALVEPGGRRPAPEGAP", "length": 742, "header": "tr|A0A8V0ZCK8-1|A0A8V0ZDZ6_CHICK Computationally mapped isoform of Semaphorin 4B OS=Gallus gallus OX=9031 GN=SEMA4B PE=3 SV=1 CANONICAL=A0A8V0ZDZ6-1" }, "locus": { "chromosome": "10", "start_pos": 20069907, "end_pos": 20063477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048961.1", "url": "https://www.ensembl.org/id/ENSGALT00010048961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028940.1", "url": "https://www.ensembl.org/id/ENSGALP00010028940.1" } ] } }, { "isoform_ac": "A0A8V0ZDZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6/entry#A0A8V0ZDZ6-1", "sequence": { "sequence": "MPVLCSGSCYARPWGLRVLLTVLCAGARDGQPRISRVLAGRAPSPCRAVPGRCPWPCARSDIGDSAERVVQRFEVPGVSNYTALLLSPDGGTLYLGAREVLFAVNTSHFQHGVLARRLPWGADEEKKRQCVFKGKDPQRDCHNYIKMLLQLNSTHLYTCGTCAFSPTCAYINVQHFTLERDALGRVLLEDGKGRCPFDPEYRSTAVMVDGELYAGTVSNFQGNEPTIYRSQESRISLKTENSLSWLQDPVFVGSAFLQESLPAGNPDGDDDKVYFFFSETGKEFDYFENTIVSRIARVCKGDQGGERVLQRRWTTFLKAQLLCSHPEDGFPFNVLQDVFVLTPGEQRWRETLFYGVFTSQWNKGGLGSSAVCAFPMHSVQKAFGGLYKEVNRETQQWYTDTSPVPEPRPGTCITSHTRHLKINSSLQMPDRVLNFVKDHFLMDSPVRSQPLLLQSRLRYQQIGVHRVQGLRGTYDVLFLGTDDGRLHKAVRVNHRVHIIEEIRLFPTGQPILQLLLDHEQGLVYAASYTAVAQVPFSNCSLYRSCGECVLARDPFCAWSHGACRSTAPHPPAHPQLWAQDIEGAETERLCQPANVSQPRPRVLLPPASGTPCQRIQLPPNAVQPLPCRLLSNLASRRWLHNGTPVNASYLVLPEGALILVGSPERAGTYECWSLEEGFRKLMASYCVAVQEPGGRGFTAPETVSTSRSTSAVGSIAARLDGKTYWTEFLVMSGLFAAAMLVLILFLLHRHCDGVKALVEPGGRRPAPEGAP", "length": 771, "header": "tr|A0A8V0ZDZ6-1|A0A8V0ZDZ6_CHICK Isoform 1 of Semaphorin 4B OS=Gallus gallus OX=9031 GN=SEMA4B PE=3 SV=1 CANONICAL=A0A8V0ZDZ6-1" }, "locus": { "chromosome": "10", "start_pos": 20069907, "end_pos": 20064075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048954.1", "url": "https://www.ensembl.org/id/ENSGALT00010048954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028936.1", "url": "https://www.ensembl.org/id/ENSGALP00010028936.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ6" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": 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"id": "PTHR19134:SF285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134:SF285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESTLMPLFPFSKQPPGRRKGRAKGSATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 598, "header": "tr|A0A8V0ZCL5-1|A0A8V0ZCL5_CHICK Isoform 1 of Tyrosine-protein phosphatase non-receptor type 9 OS=Gallus gallus OX=9031 GN=PTPN9 PE=1 SV=1 CANONICAL=A0A8V0ZCL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5/entry#A0A8V0ZCL0-1", "sequence": { "sequence": "MAAELSAEEEQATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 582, "header": "tr|A0A8V0ZCL0-1|A0A8V0ZCL5_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 9 OS=Gallus gallus OX=9031 GN=PTPN9 PE=1 SV=1 CANONICAL=A0A8V0ZCL5-1" }, "locus": { "chromosome": "10", "start_pos": 2714760, "end_pos": 2710107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051948.1", "url": "https://www.ensembl.org/id/ENSGALT00010051948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031002.1", "url": "https://www.ensembl.org/id/ENSGALP00010031002.1" } ] } }, { "isoform_ac": "A0A8V0ZCL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5/entry#A0A8V0ZCL5-1", "sequence": { "sequence": "MAESTLMPLFPFSKQPPGRRKGRAKGSATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 598, "header": "tr|A0A8V0ZCL5-1|A0A8V0ZCL5_CHICK Isoform 1 of Tyrosine-protein phosphatase non-receptor type 9 OS=Gallus gallus OX=9031 GN=PTPN9 PE=1 SV=1 CANONICAL=A0A8V0ZCL5-1" }, "locus": { "chromosome": "10", "start_pos": 2715691, "end_pos": 2710107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051955.1", "url": "https://www.ensembl.org/id/ENSGALT00010051955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031007.1", "url": "https://www.ensembl.org/id/ENSGALP00010031007.1" } ] } }, { "isoform_ac": "A0A8V0ZJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5/entry#A0A8V0ZJM9-1", "sequence": { "sequence": "MATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 572, "header": "tr|A0A8V0ZJM9-1|A0A8V0ZJM9_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 9 OS=Gallus gallus OX=9031 GN=PTPN9 PE=1 SV=1 CANONICAL=A0A8V0ZCL5-1" }, "locus": { "chromosome": "10", "start_pos": 2714133, "end_pos": 2710107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051941.1", "url": "https://www.ensembl.org/id/ENSGALT00010051941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030996.1", "url": "https://www.ensembl.org/id/ENSGALP00010030996.1" } ] } }, { "isoform_ac": "A0A8V0ZJS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5/entry#A0A8V0ZJS2-1", "sequence": { "sequence": "MLKVLCFSLSLTLPRRWAKATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 590, "header": "tr|A0A8V0ZJS2-1|A0A8V0ZJS2_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 9 OS=Gallus gallus OX=9031 GN=PTPN9 PE=1 SV=1 CANONICAL=A0A8V0ZCL5-1" }, "locus": { "chromosome": "10", "start_pos": 2717041, "end_pos": 2710107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051960.1", "url": "https://www.ensembl.org/id/ENSGALT00010051960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031010.1", "url": "https://www.ensembl.org/id/ENSGALP00010031010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415308", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F716-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "ptpn9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMADRLSAEEEQATKQFLEEINKWTSQHGVSPLSWDVAVKFLMARKFDVLRAIELFHSYRETRLREGIVKLQPHKEPLRSELLSGKFTVLGVRDPSGASIALYTAKLHHPSKTGNHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSNYTNFELDLSKKILNLLKGAFPARLKKVLIVGAPVWFRVPYNLLSLLLKEKLRERVQMVKMADLRQHLPRDCLPEHLGGCLPLDVHNWNLQLLSEQNGRVDPVDELVGIPLENTSIHTPGAEAMSLAELMAHLNRAQRSGIYLEYEELRREQPPGTFTCALAAHNQERNRYGDVLCLDQTRVRLKARRNERSDYINASFMDGYKQKNAYIGTQGPLEKTYGDFWRMVWEQNVLVIVMTTRTDEGGRRKCGQYWPQEEGGQEVYGYIAVVNHRVDNHAHYNQTTLELHNTETFEQRQVTHFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQWAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTFCALDICLSQLQDVGTLNICQTVRRMRSQRAFSIQTPEQYYFCHAAILEHAQRQGLLSANQ", "length": 571 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N6W1-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRGHAEAEAHRTGLPALPGDFCPPGGGSGGGMEPATAPQPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYTNFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPQAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMTHYKKTTLEIHNIEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRNQQRLAVSSMGARTKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPPSHNLLAMEGQ", "length": 625 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SJ71-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPATAPQPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPHAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRSQQRLAVSSMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSSHNLLAMEGQ", "length": 593 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35239-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "Ptpn9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILSSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ", "length": 593 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43378-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESQ", "length": 593 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q641Z2-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "Ptpn9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYIKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIQFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRSQQSMAVGSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ", "length": 593 }, "evidence": [ { "id": "A0A8V0ZCL5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 249, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 488, "end_pos": 572, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCL5" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 581, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + 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containing H3 OS=Gallus gallus OX=9031 GN=PLEKHH3 PE=4 SV=1 CANONICAL=A0A8V0ZCM6-1" }, "locus": { "chromosome": "27", "start_pos": 4996650, "end_pos": 4990135, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051967.1", "url": "https://www.ensembl.org/id/ENSGALT00010051967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031017.1", "url": "https://www.ensembl.org/id/ENSGALP00010031017.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCN4-1", "uniprot_ac": "A0A8V0ZCN4", "uniprot_id": "A0A8V0ZCN4_CHICK", "mass": { "chemical_mass": 293347.0, "monoisotopic_mass": 293347.0 }, "refseq": { "ac": "XP_015130883", "name": "eIF-2-alpha kinase activator GCN1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130883" }, "gene_names": [ { "name": "GCN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ] }, { "name": "GCN1", "type": "synonym", "evidence": [ { "id": "XP_015130883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130883" } ] } ], "protein_names": [ { "name": "GCN1 activator of EIF2AK4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4/entry#names_and_taxonomy" } ] }, { "name": "eIF-2-alpha kinase activator GCN1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015130883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130883" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015130883.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130883" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GCN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4", "locus": { "chromosome": "15", "start_pos": 9485136, "end_pos": 9444510, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021435", "url": "https://www.ensembl.org/id/ENSGALG00010021435" } ] } } ], "crossref": [ { "id": "416982", "url": "https://www.ncbi.nlm.nih.gov/gene/416982", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416982", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416982", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYATQRG", "url": "https://omabrowser.org/oma/group/KYATQRG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23346:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23346:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24987", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24987", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24993", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24993", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26715", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26715", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130883", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADTQISDTLKRFAVKVTTASVKERREILSELGKCISGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQLALQQLAESQPDATAKNLLQSLQSSGISGKAGAPSKSSGSAALLALSWTCLLVRTVFPTPDKRQGETWKKLVEVQCLLLLEVLGGSHKQAVVGAVKKLNRLWKENQDLVDQYLSAILGLEPNQSYAAMLGLVVQFCTAQKETDIIKRHKSALLDFYVKTILMSKTKPQKHVLDSCSPLLRYISHAEFKDLLLPTLQKSLLRSPENVIETISCLLLSVNLDLSQYALDIVKGLAGHLKSNSVQLMDEAVVALKNLARQCSDPSAVESLSRHLFAILGGSEGKLTVVAQKMSVLSGIGSLSHHVVSGSSSQALAGTVAELFIPFLQQEVHEGTLVHAVSVLALWCVRFTTEVPKKMVEWLKKAFGLKTSTSAVRHAYLQCMLASFKGDTLLQAMDLLPMLIQTVEKAASQSTQIPMVTEGVAAALLICRMSVIEGQTESKLSGFWQLILDEKKQIFTSEKFLQSASEEAMCTVLQLTERLLLDHAQRLPESKIQQYHRALVAVLLSRTWHVRRQAHQTVRKLLSSLGGYKLAYGLLEELKVVLSSHKVMPQEVLVMESGELSEQGKTYIPPRVLHEALCVISSVAGLDVDSFETEKLALEMLLVSHHPSLVAIQPGLWPALLVKMKIDPKDFITKHLNDILPRLTAYSPDNQSSMNAVGSLSLLSPGRVLPQLISTISASMQNPALCQVTREEFAIMKTPEGELYDKSIIQSAQQDSMKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKDEVQLTSKQKELMHAQLEKESQIRKRLKELDNELETALGLLDTVIKRKPPGLTQYIPSLVGSFLPLFRSPLAAPRIKDPFLSLASCVMPARLKTFGTLVSHVTLRLMKPECELDESWCQEELPTALNRVVSLLHAHTIPSRTGKGEAGAAPLSAPAFSLVFPLLKTAMTETSHDSEDKEEFLVKILQILTVHAQLRSSTNGQALLVDENGPELLPRRDMLLLLTRVIATGSPRLQVLASNALTSVCTSSSGEDGCAYAEQEEIDVLLQALQSPCMNVRDAALRGLMELQMVLPTPDSDEKNGLNLLRRLWVVKFDVEDEIQKLAERLWESMGLELQPDLCSLLIKDVIYHEEAVRQAGAEALSKAVAQYQNQAAEVMNKLTEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGIALALNKLSEHLDSSQVKPLFQFFVPDALNDRNPEVRKCMLDAALSTLNTHGKDNVNSLLPVFEEFLKNAPNDASYDAVRQSVVILMGSLAKHLDKSDPKVKPIVGKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQKLMQLLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMTTLTDAIQDKKNFRRREGALFAFEMLCSMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSTHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQNAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFIPYVGPIIPCILKALADENEFVRDTALRAGQRIISMYAETAIALLLPQLEDGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIINALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLKFLASTCADKRTVAARTLGDLVRKLGEKILPEIIPILEDGLRSDKNDERQGVCIGLSEIMKSTSRDAVLVFSESLVPTVRKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDNEETSDFAVDGLKQVMAVKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLSVILPAMMSALKEKLGTSEEQLEMANCQSVILSVEDDVGQRIITEDLLEATRSPDVGMRQAAAIILNIYCSKTKADYTGHLKNLVSGLIRLFNDTNPVVLNESWDALNSITKKLDAGNQLALIEDLHKDIRVVGNEAKGEHVPGFCIPKKGVTSILLVLREGVLTGNPEQKEEAAKALGLVIKLTSAEALKPSVVSITGPLIRILGDRFSWNVKVALLETLSLLLAKVEIALKPFLPQLQTTFTKALQDSNRAVRLKAADALGKLIVIHVKVDPLFTELLNGIRSSDDSAIRDTMLQALRFVTRGAGAKVDATIRKNISTVLLGMLGHDEDATRMASAGCLAELCAFLSEEELNTVLHQHLLADISGIDWMVRHGRSLALSVAVNVAPYRLCSPKYYNSVLEMILSNATADRIPIAVSGIRGMGFLMKYHMEEGGNLPPKLSNLFIKCLQNSSSDIKLVAEKMIWWANKNHLPALDPQTIKPILKALLDNTKDKNTSVRAYSDQAIVNLLKMRVGEQVLESVSKILDAASLELLNESCRRSLKKLAGQADSDEQIDDTILT", "length": 2670, "header": "tr|A0A8V0ZCN4-1|A0A8V0ZCN4_CHICK Isoform 1 of GCN1 activator of EIF2AK4 OS=Gallus gallus OX=9031 GN=GCN1 PE=1 SV=1 CANONICAL=A0A8V0ZCN4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4/entry#A0A8V0ZCN4-1", "sequence": { "sequence": "MAADTQISDTLKRFAVKVTTASVKERREILSELGKCISGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQLALQQLAESQPDATAKNLLQSLQSSGISGKAGAPSKSSGSAALLALSWTCLLVRTVFPTPDKRQGETWKKLVEVQCLLLLEVLGGSHKQAVVGAVKKLNRLWKENQDLVDQYLSAILGLEPNQSYAAMLGLVVQFCTAQKETDIIKRHKSALLDFYVKTILMSKTKPQKHVLDSCSPLLRYISHAEFKDLLLPTLQKSLLRSPENVIETISCLLLSVNLDLSQYALDIVKGLAGHLKSNSVQLMDEAVVALKNLARQCSDPSAVESLSRHLFAILGGSEGKLTVVAQKMSVLSGIGSLSHHVVSGSSSQALAGTVAELFIPFLQQEVHEGTLVHAVSVLALWCVRFTTEVPKKMVEWLKKAFGLKTSTSAVRHAYLQCMLASFKGDTLLQAMDLLPMLIQTVEKAASQSTQIPMVTEGVAAALLICRMSVIEGQTESKLSGFWQLILDEKKQIFTSEKFLQSASEEAMCTVLQLTERLLLDHAQRLPESKIQQYHRALVAVLLSRTWHVRRQAHQTVRKLLSSLGGYKLAYGLLEELKVVLSSHKVMPQEVLVMESGELSEQGKTYIPPRVLHEALCVISSVAGLDVDSFETEKLALEMLLVSHHPSLVAIQPGLWPALLVKMKIDPKDFITKHLNDILPRLTAYSPDNQSSMNAVGSLSLLSPGRVLPQLISTISASMQNPALCQVTREEFAIMKTPEGELYDKSIIQSAQQDSMKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKDEVQLTSKQKELMHAQLEKESQIRKRLKELDNELETALGLLDTVIKRKPPGLTQYIPSLVGSFLPLFRSPLAAPRIKDPFLSLASCVMPARLKTFGTLVSHVTLRLMKPECELDESWCQEELPTALNRVVSLLHAHTIPSRTGKGEAGAAPLSAPAFSLVFPLLKTAMTETSHDSEDKEEFLVKILQILTVHAQLRSSTNGQALLVDENGPELLPRRDMLLLLTRVIATGSPRLQVLASNALTSVCTSSSGEDGCAYAEQEEIDVLLQALQSPCMNVRDAALRGLMELQMVLPTPDSDEKNGLNLLRRLWVVKFDVEDEIQKLAERLWESMGLELQPDLCSLLIKDVIYHEEAVRQAGAEALSKAVAQYQNQAAEVMNKLTEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGIALALNKLSEHLDSSQVKPLFQFFVPDALNDRNPEVRKCMLDAALSTLNTHGKDNVNSLLPVFEEFLKNAPNDASYDAVRQSVVILMGSLAKHLDKSDPKVKPIVGKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQKLMQLLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMTTLTDAIQDKKNFRRREGALFAFEMLCSMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSTHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQNAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFIPYVGPIIPCILKALADENEFVRDTALRAGQRIISMYAETAIALLLPQLEDGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIINALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLKFLASTCADKRTVAARTLGDLVRKLGEKILPEIIPILEDGLRSDKNDERQGVCIGLSEIMKSTSRDAVLVFSESLVPTVRKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDNEETSDFAVDGLKQVMAVKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLSVILPAMMSALKEKLGTSEEQLEMANCQSVILSVEDDVGQRIITEDLLEATRSPDVGMRQAAAIILNIYCSKTKADYTGHLKNLVSGLIRLFNDTNPVVLNESWDALNSITKKLDAGNQLALIEDLHKDIRVVGNEAKGEHVPGFCIPKKGVTSILLVLREGVLTGNPEQKEEAAKALGLVIKLTSAEALKPSVVSITGPLIRILGDRFSWNVKVALLETLSLLLAKVEIALKPFLPQLQTTFTKALQDSNRAVRLKAADALGKLIVIHVKVDPLFTELLNGIRSSDDSAIRDTMLQALRFVTRGAGAKVDATIRKNISTVLLGMLGHDEDATRMASAGCLAELCAFLSEEELNTVLHQHLLADISGIDWMVRHGRSLALSVAVNVAPYRLCSPKYYNSVLEMILSNATADRIPIAVSGIRGMGFLMKYHMEEGGNLPPKLSNLFIKCLQNSSSDIKLVAEKMIWWANKNHLPALDPQTIKPILKALLDNTKDKNTSVRAYSDQAIVNLLKMRVGEQVLESVSKILDAASLELLNESCRRSLKKLAGQADSDEQIDDTILT", "length": 2670, "header": "tr|A0A8V0ZCN4-1|A0A8V0ZCN4_CHICK Isoform 1 of GCN1 activator of EIF2AK4 OS=Gallus gallus OX=9031 GN=GCN1 PE=1 SV=1 CANONICAL=A0A8V0ZCN4-1" }, "locus": { "chromosome": "15", "start_pos": 9484574, "end_pos": 9444528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051981.1", "url": "https://www.ensembl.org/id/ENSGALT00010051981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031027.1", "url": "https://www.ensembl.org/id/ENSGALP00010031027.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1115, "start_aa": "Thr", "end_pos": 1115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1115", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1350, "start_aa": "Thr", "end_pos": 1350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1350", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416982", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416982", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PVA8-1", "protein_name": "Stalled ribosome sensor GCN1", "gene_name": "Gcn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADTQVSETLKRFAVKVTTASVKERREILSELGRCIAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGVGSKACVPSKSSGSAALLALTWTCLLVRIVFPLKAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYFSAILSLEPSQNYAAMLGLLVQFCTNHKEMDAVSQHKSTLLEFYVKNILMSKAKPPKYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYALDIVKGLANQLKSNSPRLMDEAVLALRNLARQCSDSSATEALTKHLFAILGGSEGKLTIIAQKMSVLSGIGSLSHHVVSGPSGQVLNGCVAELFIPFLQQEVHEGTLVHAVSILALWCNRFTTEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCMLASFRGDTLLQALDFLPLLMQTVEKAASQGTQVPTVTEGVAAALLLSKLSVADAQAEAKLSGFWQLVVDEKRQTFTSEKFLLLASEDALCTVLRLTERLFLDHPHRLTNSKVQQYYRVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGVKLANGLLDELKTVLNSHKVLPLEALVTDAGEVTEMGKTYVPPRVLQEALCVISGVPGLKGDIPSTEQLAQEMLIISHHPSLVAVQSGLWPALLTRMKIDPDAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALCLVTREEFSIMQTPAGELFDKSIIQSAQQDSIKKANMKRENKAYSFKEQIIEMELKEEIKKKKGIKEEVQLTSKQKEMLQAQMDKEAQIRRRLQELDGELEAALGLLDAIMARNPCGLIQYIPVLVDAFLPLLKSPLAAPRVKGPFLSLAACVMPPRLKTLGTLVSHVTLRLLKPECALDKSWCQEELPVAVRRAVSLLHTHTIPSRVGKGEPDAAPLSAPAFSLVFPMLKMVLTEMPYHSEEEEEQMAQILQILTVHAQLRASPDTPPERVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTALCASSSGEDGCAFAEQEEVDVLLAALQSPCASVRETALRGLMELRLVLPSPDTDEKSGLSLLRRLWVIKFDKEDEIRKLAERLWSTMGLDLQSDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRNPDVRKCMLDAALATLNAHGKENVNSLLPVFEEFLKDAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAVKEDAGGMIQRLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVDRRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLFFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEEVSEFALDGLKQVMAVKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNMYCSRSKADYSSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRFIGNECKGEHVPGFCLPKRGVTSILPVLREGVLTGSPEQKEEAAKGLGLVIRLTSADALRPSVVSITGPLIRILGDRFNWTVKAALLETLSLLLGKVGIALKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHVKVDPLFTELLNGIRAVEDPGIRDTMLQALRFVIQGAGSKVDAAIRKNLVSLLLSMLGHDEDNTRISTAGCLGELCAFLTDEELNTVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPSRLCAGRYSNEVQDMILSNAVADRIPIAMSGIRGMGFLMKYHIETGSGQLPPRLSSLLIKCLQNPCSDIRLVAEKMIWWANKEPRPPLEPQTIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRRGEELLQSLSKILDVASLEALNECSRRSLRKLACQADSVEQVDDTILT", "length": 2671 }, "evidence": [ { "id": "A0A8V0ZCN4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LRI5-1", "protein_name": "Stalled ribosome sensor GCN1", "gene_name": "Gcn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADTQVSETLKRFAVKVTTASVKERREILSELGRCIAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGVGSKACVPSKSSGSAALLALTWTCLLVRIVFPLKAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYFSAILSLEPNQNYAGMLGLLVQFCTNHKEMDVVNQHKSTLLEFYVKHILMSKAKPPKYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYALDIVKGLANQLKSNSPRLMDEAVLALRNLSRQCSDSSATEALTKHLFAILGGSEGKLTIIAQKMSVLSGIGSLSHHGVSGPSGQVLNGCVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTTEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCMLASFRGDTLLQALDFLPLLMQTVEKAASQSTQVPTVTEGVAAALLVSKLSVADSQAEAKLSNFWQLVVDEKKQIFTSEKFLLLASEEALCTVLHLTERLFLDHAHRLTNSRVQQYYRVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGIKLANGLLEELKTVLNSHKVLPLETLVTDAGEVMETGKTYVPPRVLQEALCVISGVPGLKGDITSTEQLAQEMLIISHHPSLVAVQSGLWPALLTRMKIDPEAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSILSPDRVLPQLISSITASVQNPALCLVTREEFAVMQTPAGELFDKSIIQSAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQMDKEAQIRRRLQELDGELEAALGLLDAIMTRNPRGLTQYIPVLVDAFLPLLKSPLAAPRVKGPFLSLAACVMPPRLKTLGTLVSHVTLRLLKPECALDQSWCQEELPVAVRRAVSLLHTHTIPSRVGKGEPDAAPLSAPAFSLIFPMLKMVLTEMPYHSEEEEEQMAQILQILTVHAQLRASPDTPPERVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTALCASSSGEDGCAFAEQEEVDVLLAALQSPCASVRETALRGLMELHLVLPAPDTDEKNGLNLLRRLWVVKFDKEEEIRKLAERLWTTMGLDLQSDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRNPDVRKCMLDAALATLNAHGKENVNSLLPVFEEFLKDAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAVKEDAGGMIQRLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVDRRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEEVSEFALDGLKQVMAVKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNMYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLGESWDALNAITKKLDAGNQLALIEEFHKEIRYIGNECRGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWSVKAALLETLSLLLGKVGIALKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRVVEDPGIRDTMLQALRFVIQGAGAKVDAAIRKNIVSLLLGMLGHDEDNTRISSAGCLGELCAFLTEEELNTVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPSRLCTGKYSNEVQDMVLSNAVADRIPIAVSGIRGMGFLMKYHIETGGGQLPPRLSTLLIKCLQNPSSDIRLVAEKMIWWANKEPRPALEPQAIKPILKALLDNTKDKNTVVRAYSEQAIVNLLKLRQGEELLQSLSKILDVASLEALNECSRRSLKKLACQADSVEQVDDTILT", "length": 2671 }, "evidence": [ { "id": "A0A8V0ZCN4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7PLL6-1", "protein_name": "Lethal (3) 80Fj, isoform A", "gene_name": "l(3)80Fj", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDEQLSAALRDLPGRVLNVPVEERQHLFQNVSSVLKNSGINSTIIRGICKVIGTTITKYKDPTSQRIVRDLIVDLVTIHHDLTIEHMLNVFKAFIYKEFASVSPQKSCKLAVIALGWISIIQKQAQRESNIFKTEKKKLIEYQTLLYQITVISPNQRVTDARTKILYDLWNNTEIFNETMDTLFQMESTSNVTIFCMAMFQFKYKNCNALKLNQYTEKLSEYFVKSMISCKHKPDKSFIIACSPLLKSLTDAEFDSYIYPSLQRSILRSPENTLQSIGLIFNMLNFDCSRYAQKVGIVLIKNLYSKGDIARQESLESLKLLSTKCSNWIIVKELLERIFSVLNGSDGKINVIEYRINILQGAGNLSFNNIDQDHMPNILNEAVTLFSKALECETQEKVICCTLEMFGLWTQKFIHNLPDVVINIFTSGMRLKTTNQIIRQSYLEWLLLSIQNAEVNNHISIIQDLISFYTKALQNSSQSCYLSEAACIACILLILEKPSENYNFFWTTVFDMKKLIFYNEKFTTTAPIPTLCNISLMARILINSYPEKIKGKLEPLARTLVSNLCCNSVKVRVYTAKQVKQIINSSSGIEFVKLALCEFGKRINLVNIETDGEPLIDQFGTSNQVYVDALLTLTSIKHITYEDSVDVAIDLLLISHHPAIVSNEPYLWETTIQKHLNLDAKNVILAKTNEIVNEYIDNYIASAQYENTISALIRICPNLIVPTVVNNLKNYLSNFSNYNVSNEEYLIFLTPDGELFDKSVIPHIDSQYETVRLKRENKVYSYKEQLEEIQLRREIDDKREKEGKLKTIRYTQKQEEQIKNQMEKELHIKLRITLLYEKLISKISLLKASCSGNGEQMAQHFYSLLDGILNASKSPLCAEVLTDLYIFLHNLCFTFQPKLGRAIALATIKLQSPSCVLKKEFEAFNVNQAINDIIIDLDNHVKSNYLDSPSFSYAFEFLKRALLLLNTDSDFDLISKGIQILALHTSAGVCCKPQFMPRFGMFKMLLDLLKNNNKLWAQTSAAILQVAKCSNGDNCSSPDNHIISIFLQALQHCSDAVRKVALQSLKIMVNGIVNHIKVDNSLEKVIINRFWVAKHDPEEENRELALFLWNTAKFPLPGYVDIINDITHSETCIQKSASESLIPLLAGDEVLKKCVIKKLFSIYKAKLSLLPPVLDQFDREIEPAIDQWKPRRGIAIAFSTIAFLLSIEDINDIMNFMVSQGLGDREDVVHKEMLATALKIVDLHGNKAIENLLPVFEDFLDKAPKSQSYDNIRQAVVILMGSLARHLEKDDKRIDPIVKRLITSLSTPSQQVQEAVSNCLPHLMPSVKDEAPSMIKKLLHSLAKSEKYGERRGAAYGIAGIVKGLGILSLKQLDIMSKLTAFIQDKKNYRSREGALFAFEVLCSTLGRLFEPYIVHVLPHLLQCFGDPSQYVRQAADDTAKVVMRKLSAHGVKLVLPSLLEALDEDSWRTKTASVELLGAMAFCAPKQLSSCLPSIVPKLIQVLGDSHTKVQESGGEALKVIGSVIKNPEIQAIVPVLLDALEDPSNNTSTCLQSLLKTKFIHFIDAPSLALIMPVVQRAFMDRSTETRKMAAQIIGNMYSLTDQKDLAPYLPSIIPGLKSSLLDPVPEVRAVSARALGAMVKGMGESSFENLLPWLMETLTSESSSVDRSGAAQGLSEVVGGLGVEKMHKLMPEIISTAERVDIAAHVKDGYIMMFIYMPGAFQEEFTPYIGQIINPILKALADESEFVRDTALKAGQRIVNLYAETAVALLLPELEKGLFDDNWRIRYSSVQLLGDLLYRISGVSGKMTTETASEDDNFGTEHSHTAIIHFLGDERRNRVLSGLYMGRSDVSLMVRQAALHVWKVVVTNTPRTLREILPTLFGLLLGCLASTSYDKRQVAARTLGDLVRKLGERVLPEIIPILENGLNSDHPDQRQGVCIGLSEIMGSTSKEMVLTFIDSLVPTVRKALCDPLPEVREAAAKTFESLHSTVGSRALDEILPFMLQGLSDADPFVAENTLDGLRQVMSIKSKVVLPYLVPQLTSPPVNTKALSILVSVAGEALIKYLPKILSSLLEALSDAYGYPNEPQENEYCQTVILSVTDETGIRTIMDTLLISANSSDLCTRKSAASLLSAFCIHSPGNYYEYIPQLLRCLLKLLVESDKDILQKSWEALNAVIKGMNAAQQICHVSDVRQAVRFAASELEGTELPGFCLPKGITPLLPVFREAILNGLPEEKENAAQGLGEVIFLTNAKSLQPSVVHITGPLIRILGDRFNAAVKAAVLETLSILLHKVGVMLKQFLPQLQTTFLKALHDQNRNVRMKAGKALSELVAIHSRAEPLFNEIHNGIKNSDDSSVRETMLHALRSIVSRSGDKMSEPIKKQIYVTLLSMIGHHEDATRSAVGGCLGAILKYIASGHVYDLFNNIILTNNTDDLIVKHGHTIVLFVALKECPTEVLVLDLPEKITSYVLINILSEKVPIASNAVRAATYLLDYYLVNQNEPPIKIVMALSRAMNHSSNDVKQLVAQSCTYLSKNLAANQSSIDVLKYLVPMLVNGTKEKNGYVKSNSELALISILRLRSDDTSFLKISGLLESGARDSLNDVVLKVLKRTSSQSIIKEEELDDTLQS", "length": 2630 }, "evidence": [ { "id": "A0A8V0ZCN4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q92616-1", "protein_name": "Stalled ribosome sensor GCN1", "gene_name": "GCN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWTCLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPKYLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIVKGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKMSVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTMEVPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQSTQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALCTVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKLAHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDVTDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQSAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDREAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNPFLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTITSRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASPNTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAEQEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEEIRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQRLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNRRSLKKLASQADSTEQVDDTILT", "length": 2671 }, "evidence": [ { "id": "A0A8V0ZCN4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "stalled ribosome sensor activity", "id": "GO:0170011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "GCN2-mediated signaling", "id": "GO:0140469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" }, { "name": "protein-RNA covalent cross-linking repair", "id": "GO:0160127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2202, "end_pos": 2204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2210, "end_pos": 2212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2426, "end_pos": 2428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2516, "end_pos": 2518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2560, "end_pos": 2562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2604, "end_pos": 2606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2644, "end_pos": 2646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN4" }, { "id": "SM01349", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01349" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TOG", "eco_id": "ECO_0000259", "start_pos": 1365, "end_pos": 1598, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130, 1115, 1350 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1489, "end_pos": 1491 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 2202, "end_pos": 2204 }, { "start_pos": 2210, "end_pos": 2212 }, { "start_pos": 2426, "end_pos": 2428 }, { "start_pos": 2516, "end_pos": 2518 }, { "start_pos": 2560, "end_pos": 2562 }, { "start_pos": 2604, "end_pos": 2606 }, { "start_pos": 2644, "end_pos": 2646 }, { "start_pos": 720, "end_pos": 722 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCN5-1", "uniprot_ac": "A0A8V0ZCN5", "uniprot_id": "A0A8V0ZCN5_CHICK", "mass": { "chemical_mass": 56890.0, "monoisotopic_mass": 56890.0 }, "refseq": { "ac": "XP_414779", "name": "archaemetzincin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414779" }, "gene_names": [ { "name": "AMZ2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5" } ] }, { "name": "AMZ2", "type": "synonym", "evidence": [ { "id": "XP_414779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414779" } ] } ], "protein_names": [ { "name": "Archaelysin family metallopeptidase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5/entry#names_and_taxonomy" } ] }, { "name": "archaemetzincin-1", "type": "synonym", "evidence": [ { "id": "XP_414779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414779" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414779.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414779" } ] }, { "annotation": "Probable zinc metalloprotease.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5#function" }, { "database": "UniProtKB", "id": "ARBA00024316", "url": "https://www.uniprot.org/uniprotkb/ARBA00024316#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ86#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZCN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11375", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11375", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416474", "url": "https://www.ncbi.nlm.nih.gov/gene/416474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416474", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416474", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAKWEMF", "url": "https://omabrowser.org/oma/group/LAKWEMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZCN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ86", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_414779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQCKHTQEFSFGPRALKDALISTNPALQELYAKAFSRAEKLFLSEAYNPQRTLFCTLLIRTAFDWLLSHPDAPEDFETFYHAMLRRKQSFCRKHIYLQPIDLTEGPAGPSLLDSLQSCVESFFLGLRVKCLPSIPISSIHCCYRHSRDSDRVQLHADGILNFLKNNKPMDALCVLGLTLTDLYPCETWSFTFSKFLPGQEVGVCSFARFSGDFPQASCSSLNPLTHREQLSDVSKESRERTLPFSAQEMVQCCKVTCHEICHLMGLGTCRWLQCIMQGALSLDEALLRPLEPCPICLRKLQHIVGFKLVERYRKLYAWTQTVLSTWPKQEPADLSASEDVLPLSSDSGMCCENDSEAVTSLSEPLTPDVCSQALSIGPELEQDERSCSLAEVQSQPQPAGPSQPTDVIKDYELWLEMCIAALERNVSEEELARVDKAVDALARWDMFTGQLPAMKKDLPFVRDNTGLRKVLGDKFSSLRRKLSSRKLSKGESSPHRWRWEDN", "length": 503, "header": "tr|A0A8V0ZCN5-1|A0A8V0ZCN5_CHICK Isoform 1 of Archaelysin family metallopeptidase 2 OS=Gallus gallus OX=9031 GN=AMZ2 PE=3 SV=1 CANONICAL=A0A8V0ZCN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5/entry#A0A8V0ZCN5-1", "sequence": { "sequence": "MLQCKHTQEFSFGPRALKDALISTNPALQELYAKAFSRAEKLFLSEAYNPQRTLFCTLLIRTAFDWLLSHPDAPEDFETFYHAMLRRKQSFCRKHIYLQPIDLTEGPAGPSLLDSLQSCVESFFLGLRVKCLPSIPISSIHCCYRHSRDSDRVQLHADGILNFLKNNKPMDALCVLGLTLTDLYPCETWSFTFSKFLPGQEVGVCSFARFSGDFPQASCSSLNPLTHREQLSDVSKESRERTLPFSAQEMVQCCKVTCHEICHLMGLGTCRWLQCIMQGALSLDEALLRPLEPCPICLRKLQHIVGFKLVERYRKLYAWTQTVLSTWPKQEPADLSASEDVLPLSSDSGMCCENDSEAVTSLSEPLTPDVCSQALSIGPELEQDERSCSLAEVQSQPQPAGPSQPTDVIKDYELWLEMCIAALERNVSEEELARVDKAVDALARWDMFTGQLPAMKKDLPFVRDNTGLRKVLGDKFSSLRRKLSSRKLSKGESSPHRWRWEDN", "length": 503, "header": "tr|A0A8V0ZCN5-1|A0A8V0ZCN5_CHICK Isoform 1 of Archaelysin family metallopeptidase 2 OS=Gallus gallus OX=9031 GN=AMZ2 PE=3 SV=1 CANONICAL=A0A8V0ZCN5-1" }, "locus": { "chromosome": "14", "start_pos": 3374133, "end_pos": 3367214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048575.1", "url": "https://www.ensembl.org/id/ENSGALT00010048575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028666.1", "url": "https://www.ensembl.org/id/ENSGALP00010028666.1" } ] } }, { "isoform_ac": "A0A8V0ZJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5/entry#A0A8V0ZJ86-1", "sequence": { "sequence": "MLQCKHTQEFSFGPRALKDALISTNPALQELYAKAFSRAEKLFLSEAYNPQRTLFCTLLIRTAFDWLLSHPDAPEDFETFYHAMLRRKQSFCRKHIYLQPIDLTEGPAGPSLLDSLQSCVESFFLGLRVKCLPSIPISSIHCCYRHSRDSDRVQLHADGILNFLKNNKPMDALCVLGLTLTDLYPCETWSFTFSKFLPGQEVGVCSFARFSGDFPQASCSSLNPLTHREQLSDVSKESRERTLPFSAQEMVQCCKVTCHEICHLMGLGTCRWLQCIMQGALSLDEALLRPLEPCPICLRKLQHIVGFKLVERYRLYAWTQTVLSTWPKQEPADLSASEDVLPLSSDSGMCCENDSEAVTSLSEPLTPDVCSQALSIGPELEQDERSCSLAEVQSQPQPAGPSQPTDVIKDYELWLEMCIAALERNVSEEELARVDKAVDALARWDMFTGQLPAMKKDLPFVRDNTGLRKVLGDKFSSLRRKLSSRKLSKGESSPHRWRWEDN", "length": 502, "header": "tr|A0A8V0ZJ86-1|A0A8V0ZJ86_CHICK Computationally mapped isoform of Archaelysin family metallopeptidase 2 OS=Gallus gallus OX=9031 GN=AMZ2 PE=3 SV=1 CANONICAL=A0A8V0ZCN5-1" }, "locus": { "chromosome": "14", "start_pos": 3374133, "end_pos": 3367214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048573.1", "url": "https://www.ensembl.org/id/ENSGALT00010048573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028663.1", "url": "https://www.ensembl.org/id/ENSGALP00010028663.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416474", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416474", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QFK7-1", "protein_name": "Archaelysin family metallopeptidase 1", "gene_name": "AMZ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQCRPAQEFSFGPRALKDALVSTDPGLRQLYAAAFSPAERLFLAEAYNPRRTLFGAPRIHTAFDWLLSRPEAPEDFETFHAALPPRKQSPARKHIYLQPIDLSEGLAGGALLYHLRSCTEAFFLGLQVRCLPSVAAASIHCSSRLSQDSDRLQLHTDGILSFLKSSKPGDACVLGLTLSDLYPCEAWTFTFGKFLPGHEVGVCSFARFSEEFLQLGPSAPDVALAEVAADGPEVPLQDTGQTVCFSALGMLQCCKVTCHELCHLLGLGSCRWLRCLMQGALSLDEALRRPLDLCPICLRKLQHILGFRLVDRYKRLYLWTQAVAGTQTGEEAAGEPSASVSEDTLPCSADSGLCCESDSEPGTSLSEPLSPDAWSHAFPAGAELEPEDGLGALAAAEGPGEALAEHGRWLAACIQALERAVTEEELARVDSAVDALARWEMFTGQLPAPRHDLPCGQDSAGLRRILGGTFSSLRRRLSARRLARAEVSPRRGKAEEN", "length": 498 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LYL6-1", "protein_name": "Archaemetzincin-1", "gene_name": "Amz1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLQCRPPQEFSFGPRALKDALISRDLALKQLYTSAFSPSERLFLSEAYNPHRTLFSTLLIHSAFDWLLSRPEAPEDFETFHASLQPRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRNCAEAFFLGLRVKCLPSVAAASIHCSSRPSQDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGPSLPDPALLEAAADDPETLPHEGGRTLCFSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGALSLDEAIRRPLDLCPICLRKLQHLLGFRLLERYKRLHTWTRVMVEMWSGQEAGEPSVSDDTLPFSADSGMGCESDTEPVTSPSEPVTPDAWSHVFPDGPEPGSEDGLSSLVASEVLLKLGGPIEAIEEYGQWLGACIQVLEREVAEEELVHVDAAVDAMGRWEMFTGQLPVTRQHLPCVKDNVGLRRVLGDKFFSLRRRLSSRRLAKASSSHCRWGAEN", "length": 501 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1B9T4-1", "protein_name": "Archaelysin family metallopeptidase 1", "gene_name": "AMZ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQCRPAEEFSFGPRALKDALLSTDPALRQLYTAAFSPAERLFLAEAYNPRRTLFGTLLIRTAFDWLLSRPEAPEDFQTFHAALPPRKQSLARKHIYLQPIGLSEGPAGSVLLDQLRSCTEAFFLGLQVRCLPSVAAASIHCSSRPGQDPDRLQLHTDGILSFLKSSKPGDALCVLGLTLSDLYPCEAWTFTFGTFLPGHEVGVCSFARFSGEFLPRGPSTPDLVEVEAEAAADGPEVPLQDGGQAVCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALRVDEALRRPLDLCPICLRKLQHLLGFRLVDRYKRLYAWTQAAAGTQPSPAAVGEPSVSEDTLPCSADSGLCCESDSEPGSSLSEPLSPDAWIPAGLELDAEDGLGSLAAAEGPGEALAEHGRWLAACIQALERDVSEGELERVDGAVDALAPWDLFTGRLPASRQDLPCGRDGAGLRRVLGDTFSSLRRRLSARRPSRAESPLRRQKAEDD", "length": 496 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q400C9-1", "protein_name": "Archaemetzincin-1", "gene_name": "Amz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQCRPPQEFSFGPRALKDALISCDLALKQLYTSAFSPSERLFLSEAYNPHRTLFSTLLIHSAFDWLLSRPEAPEDFETFHASLQLRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRSCAEAFFLGLRVKCLPSVASASINCCSRPARDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGSSIPDSALLEAAAGGPETLPQEGGQTLCYSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGVLSLDEALRRPLDLCPICLRKLHHLLGFRLLERYKRLHTWTRVMLEMWSGQEAGEPSVSEDTLPFSADSGMGCESDTEPVTSPSEPVTPDAWSHTFPDGPEPVSEEGLSSLAASEVLLKLGGPVDALEEYRQWLDACIQALEREVAEEELVQVDAAVDALGRWEMFTGQLPVTKQYMPCVKDNVGLRRVLGDKFSSLRRRLSSRRLAKASSSQCHWGAEN", "length": 501 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q400G9-1", "protein_name": "Archaemetzincin-1", "gene_name": "AMZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLIRTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCTEAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTLSDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQDRGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICLRKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEPGTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQREVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSARKLARAESAPRPWDGEES", "length": 498 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BVF9-1", "protein_name": "Archaemetzincin-1", "gene_name": "Amz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQCKPPQEFSFGPRALKDALISCDLALKQMYTSAFSPSERLFLSEAYNPNRTLFSTLLIHSAYDWLLSRPEAPEDFETFHASLQLRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRSCAEAFFLGLRVKCLPSVAAASINCCSRPSRDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGSSVPDSALLEAAAAGGPETLPRERGRTLCFSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGALSLDEVLRRPLDLCPICLRKLHHLLGFRLLERYKRLHAWTRVMVEIWSGQEAGEPSVSEDTLPFSADSGMGCESDTEPVTSPSEPVTPDGWSHPFPDGPEPVSEDGLGSLMASEVSLTLGGPVDAMEEYGQWLTACIQTLEREGAEEELLQVDAAVDALSRWEMFTGQLPVTKQHVPCGKDNVGLRRVLGDKFSSLRRRLSSRRFAKASSSHCRWGAEN", "length": 502 }, "evidence": [ { "id": "A0A8V0ZCN5", "url": "https://omabrowser.org/oma/group/A0A8V0ZCN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCP3-1", "uniprot_ac": "A0A8V0ZCP3", "uniprot_id": "A0A8V0ZCP3_CHICK", "mass": { "chemical_mass": 52166.0, "monoisotopic_mass": 52166.0 }, "refseq": {}, "gene_names": [ { "name": "OCSTAMP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ] } ], "protein_names": [ { "name": "Osteoclast stimulatory transmembrane protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OCSTAMP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3", "locus": { "chromosome": "20", "start_pos": 5885687, "end_pos": 5893095, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021447", "url": "https://www.ensembl.org/id/ENSGALG00010021447" } ] } } ], "crossref": [ { "id": "A0A8V0ZCP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQLLRRDAGSCLVLRPACGVRDNAYCEDSLFSKVHRIMSEQWSIYSKPVPADSRELWALFLQCSCITVLLGGLFYNWLLASLEYPWHVSVAMAVTFSLLLLLALFLVHPVRCAFSIAMPTLGTKQGRKLLLSTCIMIVVVNITPNIISNIKTLLKVILCISKNSSESLLNSTDLLGNTFWKLEHELQNYLIWKPMDGHIQFSLVKNSSLINQVHLAGEKARKDFLAVEVLVKDCVRAGNKLVAAFSVLYLCFESIWYLKNYLTNLCFDNVYITKKLRRLAEDKGASHLLVGSAPRLIRPTGLRLSREELMLCLAQALRLSVALLLVLVMVALEHLVFGVADVAVRRMAQLSTVPVTLSIKYQAGIDFLKIPFPVRDINRSYHRALTFSSASCSISPPVPPNPSVLLVVGLLFCIIYATMFLETYARRLCRKIAASFFESREDERAHYLYGKLSRQHRETQCS", "length": 463, "header": "tr|A0A8V0ZCP3-1|A0A8V0ZCP3_CHICK Isoform 1 of Osteoclast stimulatory transmembrane protein OS=Gallus gallus OX=9031 GN=OCSTAMP PE=4 SV=1 CANONICAL=A0A8V0ZCP3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3/entry#A0A8V0ZCP3-1", "sequence": { "sequence": "MSQLLRRDAGSCLVLRPACGVRDNAYCEDSLFSKVHRIMSEQWSIYSKPVPADSRELWALFLQCSCITVLLGGLFYNWLLASLEYPWHVSVAMAVTFSLLLLLALFLVHPVRCAFSIAMPTLGTKQGRKLLLSTCIMIVVVNITPNIISNIKTLLKVILCISKNSSESLLNSTDLLGNTFWKLEHELQNYLIWKPMDGHIQFSLVKNSSLINQVHLAGEKARKDFLAVEVLVKDCVRAGNKLVAAFSVLYLCFESIWYLKNYLTNLCFDNVYITKKLRRLAEDKGASHLLVGSAPRLIRPTGLRLSREELMLCLAQALRLSVALLLVLVMVALEHLVFGVADVAVRRMAQLSTVPVTLSIKYQAGIDFLKIPFPVRDINRSYHRALTFSSASCSISPPVPPNPSVLLVVGLLFCIIYATMFLETYARRLCRKIAASFFESREDERAHYLYGKLSRQHRETQCS", "length": 463, "header": "tr|A0A8V0ZCP3-1|A0A8V0ZCP3_CHICK Isoform 1 of Osteoclast stimulatory transmembrane protein OS=Gallus gallus OX=9031 GN=OCSTAMP PE=4 SV=1 CANONICAL=A0A8V0ZCP3-1" }, "locus": { "chromosome": "20", "start_pos": 5892896, "end_pos": 5886411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051998.1", "url": "https://www.ensembl.org/id/ENSGALT00010051998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031037.1", "url": "https://www.ensembl.org/id/ENSGALP00010031037.1" } ] } }, { "isoform_ac": "A0A8V0ZQM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3/entry#A0A8V0ZQM7-1", "sequence": { "sequence": "MSEQWSIYSKPVPADSRELWALFLQCSCITVLLGGLFYNWLLASLEYPWHVSVAMAVTFSLLLLLALFLVHPVRCAFSIAMPTLGTKQGRKLLLSTCIMIVVVNITPNIISNIKTLLKVILCISKNSSESLLNSTDLLGNTFWKLEHELQNYLIWKPMDGHIQFSLVKNSSLINQVHLAGEKARKDFLAVEVLVKDCVRAGNKLVAAFSVLYLCFESIWYLKNYLTNLCFDNVYITKKLRRLAEDKGASHLLVGSAPRLIRPTGLRLSREELMLCLAQALRLSVALLLVLVMVALEHLVFGVADVAVRRMAQLSTVPVTLSIKYQAGIDFLKIPFPVRDINRSYHRALTFSSASCSISPPVPPNPSVLLVVGLLFCIIYATMFLETYARRLCRKIAASFFESREDERAHYLYGKLSRQHRETQCS", "length": 425, "header": "tr|A0A8V0ZQM7-1|A0A8V0ZQM7_CHICK Computationally mapped isoform of Osteoclast stimulatory transmembrane protein OS=Gallus gallus OX=9031 GN=OCSTAMP PE=4 SV=1 CANONICAL=A0A8V0ZCP3-1" }, "locus": { "chromosome": "20", "start_pos": 5889231, "end_pos": 5886411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051994.1", "url": "https://www.ensembl.org/id/ENSGALT00010051994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031033.1", "url": "https://www.ensembl.org/id/ENSGALP00010031033.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" }, { "name": "positive regulation of osteoclast differentiation", "id": "GO:0045672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" }, { "name": "multinuclear osteoclast differentiation", "id": "GO:0072674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" }, { "name": "positive regulation of osteoclast proliferation", "id": "GO:0090290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP3" }, { "id": "PF07782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dendritic cell-specific transmembrane protein-like", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 450, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCP4-1", "uniprot_ac": "A0A8V0ZCP4", "uniprot_id": "A0A8V0ZCP4_CHICK", "mass": { "chemical_mass": 69022.0, "monoisotopic_mass": 69022.0 }, "refseq": { "ac": "XP_004944749", "name": "protein SHQ1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944749" }, "gene_names": [ { "name": "SHQ1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ] }, { "name": "SHQ1", "type": "synonym", "evidence": [ { "id": "XP_004944749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944749" } ] } ], "protein_names": [ { "name": "Protein SHQ1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4/entry#names_and_taxonomy" } ] }, { "name": "protein SHQ1 homolog", "type": "synonym", "evidence": [ { "id": "XP_004944749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944749.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4", "locus": { "chromosome": "12", "start_pos": 16643422, "end_pos": 16689484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020307", "url": "https://www.ensembl.org/id/ENSGALG00010020307" } ] } } ], "crossref": [ { "id": "A0A8V0ZCP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416096", "url": "https://www.ncbi.nlm.nih.gov/gene/416096", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416096", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416096", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HNIESAW", "url": "https://omabrowser.org/oma/group/HNIESAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDP9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE37", "url": "https://www.orthodb.org/?gene=A0A8V0ZE37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12967", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12967", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12967:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12967:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04925", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04925", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21413", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21413", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-171319", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171319", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004944749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITPDFELSQDPDFLTVIIRVPYVRVSELDLFFEGEDFKFYAKPYFLRLTLPGRVVEDGREKASYDTDKGVFTIQLPKESPGQYFEGLDMLTSLLAPKKSRTAKPLVEEIGVPAEEEEEEEEEFDWEIEQTLYKEAAEGPVPLQCYYGFGNLRSGVFQRLQDELSDVIDVKDPDQTPTDERKMKRLEAEAAKFDPDHYLADFFEDEAIQHILKYKPWWVDAHKKMMALQGESQNHGSHTLVIFSDEEREQLRKFTNKSYLLDKTSRHLVYLGLIDILLAYCYEIRVNEGDKNVESSWNVRKLSATLCWLECFTSIHDVLVSFGRRVVCYPLYRHFGLVTRAFNDTVMILQLGRAAVLKCLLDIHRIFRESDPAYILNDLFITDYCIWIQKIKSKKLAALSESLQKTTLAKSHLGFELEELEAAAVLVLEEESKLTAAGMVSRQQLPSSESETSDSEESSSTSSSETEGSDSNERESSTAEDGKINPLQGMLQEERTAPLIDCNGLRQGTNALTFEASDEKSKASLQSTSVPGKLIEELEKQMHTAMRLSEQPEGLASASGFALREQEENHVSEPVRFSKVTTGKGDFLEVPSKTNPLLFLCSTNEDED", "length": 608, "header": "tr|A0A8V0ZCP4-1|A0A8V0ZCP4_CHICK Isoform 1 of Protein SHQ1 homolog OS=Gallus gallus OX=9031 GN=SHQ1 PE=1 SV=1 CANONICAL=A0A8V0ZCP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4/entry#A0A8V0ZCP4-1", "sequence": { "sequence": "MITPDFELSQDPDFLTVIIRVPYVRVSELDLFFEGEDFKFYAKPYFLRLTLPGRVVEDGREKASYDTDKGVFTIQLPKESPGQYFEGLDMLTSLLAPKKSRTAKPLVEEIGVPAEEEEEEEEEFDWEIEQTLYKEAAEGPVPLQCYYGFGNLRSGVFQRLQDELSDVIDVKDPDQTPTDERKMKRLEAEAAKFDPDHYLADFFEDEAIQHILKYKPWWVDAHKKMMALQGESQNHGSHTLVIFSDEEREQLRKFTNKSYLLDKTSRHLVYLGLIDILLAYCYEIRVNEGDKNVESSWNVRKLSATLCWLECFTSIHDVLVSFGRRVVCYPLYRHFGLVTRAFNDTVMILQLGRAAVLKCLLDIHRIFRESDPAYILNDLFITDYCIWIQKIKSKKLAALSESLQKTTLAKSHLGFELEELEAAAVLVLEEESKLTAAGMVSRQQLPSSESETSDSEESSSTSSSETEGSDSNERESSTAEDGKINPLQGMLQEERTAPLIDCNGLRQGTNALTFEASDEKSKASLQSTSVPGKLIEELEKQMHTAMRLSEQPEGLASASGFALREQEENHVSEPVRFSKVTTGKGDFLEVPSKTNPLLFLCSTNEDED", "length": 608, "header": "tr|A0A8V0ZCP4-1|A0A8V0ZCP4_CHICK Isoform 1 of Protein SHQ1 homolog OS=Gallus gallus OX=9031 GN=SHQ1 PE=1 SV=1 CANONICAL=A0A8V0ZCP4-1" }, "locus": { "chromosome": "12", "start_pos": 16682559, "end_pos": 16645112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049009.1", "url": "https://www.ensembl.org/id/ENSGALT00010049009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028975.1", "url": "https://www.ensembl.org/id/ENSGALP00010028975.1" } ] } }, { "isoform_ac": "A0A8V0ZDP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4/entry#A0A8V0ZDP9-1", "sequence": { "sequence": "MITPDFELSQDPDFLTVIIRVPYVRVSELDLFFEGEDFKFYAKPYFLRLTLPGRVVEDGREKASYDTDKGVFTIQLPKESPGQYFEGLDMLTSLLAPKKSRTAKPLVEEIGVPAEEEEEEEEEFDWEIEQTLYKEAAEGPVPLQCYYGFGNLRSGVFQRLQDELSDVIDVKDPDQTPTDERKMKRLEAEAAKFDPDHYLADFFEDEAIQHILKYKPWWVDAHKKMMALQGESQNHGSHTLVIFSDEEREQLRKFTNKSYLLDKTSRHLVYLGLIDILLAYCYEIRVNEGDKNVESSWNVRKLSATLCWLECFTSIHDVLVSFGRRVVCYPLYRHFGLVTRAFNDTVMILQLGRAAVLKCLLDIHRIFRESDPAYILNDLFITDYCIWIQKIKSKKLAALSESLQKTTLAKSHLGFELEELEAAAVLVLEEESKLTAAGMVSRQQLPSSESETSDSEESSSTSSSETEGSDSNERESSTAEDGKINPLQGMLQEERTAPLIDCNGLRQGTNALTFEASDEKSKASLQSTSVPGKLIEELEKQMHTAMRLSEQPEGLASASGFALREQEENHVSEPVRFSKHK", "length": 581, "header": "tr|A0A8V0ZDP9-1|A0A8V0ZDP9_CHICK Computationally mapped isoform of Protein SHQ1 homolog OS=Gallus gallus OX=9031 GN=SHQ1 PE=1 SV=1 CANONICAL=A0A8V0ZCP4-1" }, "locus": { "chromosome": "12", "start_pos": 16682559, "end_pos": 16645125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049012.1", "url": "https://www.ensembl.org/id/ENSGALT00010049012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028977.1", "url": "https://www.ensembl.org/id/ENSGALP00010028977.1" } ] } }, { "isoform_ac": "A0A8V0ZE37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4/entry#A0A8V0ZE37-1", "sequence": { "sequence": "MITPDFELSQDPDFLTVIIRVPYVRVSELDLFFEGEDFKFYAKPYFLRLTLPGRVVEDGREKASYDTDKGVPAEEEEEEEEEFDWEIEQTLYKEAAEGPVPLQCYYGFGNLRSGVFQRLQDELSDVIDVKDPDQTPTDERKMKRLEAEAAKFDPDHYLADFFEDEAIQHILKYKPWWVDAHKKMMALQGESQNHGSHTLVIFSDEEREQLRKFTNKSYLLDKTSRHLVYLGLIDILLAYCYEIRVNEGDKNVESSWNVRKLSATLCWLECFTSIHDVLVSFGRRVVCYPLYRHFGLVTRAFNDTVMILQLGRAAVLKCLLDIHRIFRESDPAYILNDLFITDYCIWIQKIKSKKLAALSESLQKTTLAKSHLGFELEELEAAAVLVLEEESKLTAAGMVSRQQLPSSESETSDSEESSSTSSSETEGSDSNERESSTAEDGKINPLQGMLQEERTAPLIDCNGLRQGTNALTFEASDEKSKASLQSTSVPGKLIEELEKQMHTAMRLSEQPEGLASASGFALREQEENHVSEPVRFSKVTTGKGDFLEVPSKTNPLLFLCSTNEDED", "length": 567, "header": "tr|A0A8V0ZE37-1|A0A8V0ZE37_CHICK Computationally mapped isoform of Protein SHQ1 homolog OS=Gallus gallus OX=9031 GN=SHQ1 PE=1 SV=1 CANONICAL=A0A8V0ZCP4-1" }, "locus": { "chromosome": "12", "start_pos": 16682559, "end_pos": 16645112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049011.1", "url": "https://www.ensembl.org/id/ENSGALT00010049011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028976.1", "url": "https://www.ensembl.org/id/ENSGALP00010028976.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416096", "resource": "KEGG Pathway" }, { "id": "R-GGA-171319", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171319", "resource": "Reactome", "description": "Telomere Extension By Telomerase" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L1R0-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "shq1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MITPAFELSQDADFLIVVIRVPYTRTSDFDIYIQEEEFKFYAKPYFLRLTLPGRIVEDGREKASFDIDKGLFTLHVPKETAGQHFEGLEMLTSLLAPKGSRSAKPLVEDSEACGEGCEEEDEEFDWQIEQEVYTEAPADTLKEYHKYGFGNLRSGVFSRLQEELNEVIDMKDPDNTNAELRRRNRLDTETAVFCADHYLVNLYEDKEEIRNLLKFKPWWRKLNPDPSAGYDISMTFTEEEREQMRRFTNRSYLLDKKARFHVWLGLVDIILAYVYDVRTTEGEHNVESAWTIRKLSGTLSWLETYHSVQDVLVSFGRRTYCYPLYRHFSLVTLAVKDAACIFQAGKACILKCLLAIHKIFRENDPAYILNDLYITDYCIWIQRVKSKHVLALAEPLNNAKLQKNHLELELEIIEQAAELAVKEEEEKDTESDTDDSSSSSGDSDDEDDSDEECPEKAAEKKQTAFKAHAEAVTEAFCVELQRGDGRLIEELGKRLEEELTIEEDVPQERRSASEGEGERRREHYHPHAAESERDTTKAATGKELLDVCLQRKPLRILNTEELDSDDDDDDDDDGDLRITVVDERG", "length": 585 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SFN0-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTPAFDLSQDPDFLTIAIRVPYARVSEFDVYFEGLDFKFYAKPYFLRLTLPGRIVENGREQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRTAKLLVEEIGVSEVSEEGVEDDDEEFDWEIEQSPYEEVPESALNPECRYGFGNLRSGVFQRLQDELSEVIDIKDPDFTPAAERRQKRLAAELAKFDPDHYLADFFEDEAVKQVLEYIPWWTDLYSKIMPSSKRNQEPEDFTALVSFSEEEKYQLRNFVNKSYLLDKRAHRQVYYSLIDILLAYCYETRVTEGEKNVESAWNIRKLSPTLCWFETWSNVHEILVSFGRRVLCYPLHRHFKLVMEAYRDTIKILQLGKSAVLKCLLDIHKIFQENDPAYILNDLYISDYCVWIQKAKSKKLSALADALREASLTKAQLGLELEELEAAALLVQEEETASTAGAQSVSGQQEAASSSDTSDSEESDSTFSSETDDSDSEEEEPRDSESGAVNSLLGPFVENSHAALLLDNGLICRDKAPPKSDVCQGQLPAPSLAPGASGPLIQELGEQLETTVYISEPEGSTAGKQGSIQEKDGQQTLED", "length": 579 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GS48-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "Shq1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTPAFELSQDSEFLTVAIRIPHARASEFDVYFEGVDFKFYAKPYFLRLTLPGRIVENGSEQGTYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRSAKPLVEEIGASGVSEEGADDEDSEFDWEIEQTPYEEVSESALLSQCHYGFGNLRAGVVQRLQDELSEVIDIKDPDFTPATERRQKRLAAELAKFDSDHYLADFFEDEAVEQILKYSPWWNDAHAEMMASLGKSQEKGDDAALVSFSEEEKYQLRKFVNKSYLLDKTAHRQVYYSLVDILLAYCYEIRVTEGEHNVESAWTIRKLSPTLCWFETWTDVHEILVSFGRRVLCYPLYRHFKLVMKAYRDTIKILQLGKSAVLKCLLDVHKIFQENDPAFILNDLYISDYCVWIQKAKSKKLAALAEAMKAVSLSKAQLGLELQELEAAALLVQEEETAEKAAQCNPMQPAPGSSPETSDSDSTTSSDTEDSASEQEELVGMQPSLLTSLQVPLLEEDSSALLIKESGLCRNVAGQECEVSQGQTRAPLIEEVGDELRTMLQISTPPDVSAGSHSGMQDGEERGQVPHD", "length": 567 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P40486-1", "protein_name": "Protein SHQ1", "gene_name": "SHQ1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MITPRFSITQDEEFIFLKIFISNIRFSAVGLEIIIQENMIIFHLSPYYLRLRFPHELIDDERSTAQYDSKDECINVKVAKLNKNEYFEDLDLPTKLLARQGDLAGADALTENTDAKKTQKPLIQEVETDGVSNNIKDDVKTIGQMGEGFNWEIEQKMDSSTNNGILKTKYGFDNLYDTVISVSTSNGNDINELDDPEHTDANDRVIERLRKENLKFDPEYYVSEYMTHKYGNEEDLEINGIKELLKFTPSIVKQYLQWYKDSTNPNLVMPIEFTDEEQKQMQDNLPKKSYLVEDIKPLYVTILSVLFSYVFEQIENEGTHTTESAWTMGKLCPQISFLDQQLKQVNELQDGMKEISKVNKDSSLIKIAIITGIRRALSYPLHRNYDLAMKAWTFVYYILRGGKRLVIRALLDIHETFRFHDVYYVYDKVLLDDLTAWFISQGSENVIRSLALEMRKEQESLSKQDIEFECIASFNEQTGEPEWETLNIREMEILAESEYREQQQNPQ", "length": 507 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHH1-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTPAFDLSQDPDFLTVAIRVPYARVSEFDVYFEGVDFKFYAKPYFLRLTLPGRIVENGNEQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRTAKPLVEEIGASEVSEGGVEDDDDEFDWEIEQSPYEEVPESALNPNCRYGFGNLRSGVFQRLQDELSDVIDIKDPDFTSAAERRQKRLAAELAKFDPDHYLADFMEDEAVKQVLEYNPWWSDLYSEMMTSLGKSQEEENLAALVSFSEEEKYQLRKFVNKSYLLDKKAHRQVYYSLIDILLAYCYETRVTEGERNVESAWNIRKLSPTLCWFETWTNVHEILVSFGRRVLCYPLYRHFKLVMKTYRDTIKILQLGKSAVLKCLLDIHKIFQENDPAYILNDLYISDYCVWIQKAKSKKLAALAEALKKASLTKAQLGLELEELEAAAFLVQEEEATSKAGVHSTSRQQTPSSSSETSGSEESEGSASLETEESDSEQEEPGGGESETGHSLLGPFVEESSMALLLNDGGMCRSTTFLGSDGGRGQPLASPGAPIAFGPLIQELGEQLETSVQISEPKDSAAGQQDSVLERESRQTPED", "length": 579 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55EC4-1", "protein_name": "CS domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIIPKFSVDQNDEFIIVVAITPYIKASEADFYLLENQFKFYCKPYFLRLTFSHNIVENGKEKASFNVNTQEFTFYLPKEINGQKFNDLDLITKLLEKKSTTNTSKIQVLNGESNQDDQDEDEEGEDYEDEEWEFEQIVEPEPSLDELKNKIKYGFNDGYSDFFQGLQQDISDIIDIPIIDSITKQERTKVRTEFEDLKFDPERFMENHFFNDDIKELLHYKCYWEDLIEKKLKLKNEKNQKQSSEQESNEIINKKEEEKQEEKQEEKVEEIKEKVEEIKQIDPSNLEDYDEGNDEVTNETTIESNEISDELLEKINSTLSKKISIVNDESDIKNSLIEKEDSTTTTTTTTTTTTTTTKSTTTNNNKYSKKLITFSDEEKDIMKNLPNKEYMISNEKSILLGLVDIIYSYAYNERVNMGYENIESAWNICKLSGTLSCLDNFYNLSSVLECCFKRSLTFPLYRSWLLSERVLRDTKQIFQLGKRSLLKCLLDIKKKLESSEFKYYLNRLYIDDYCIWLQHASKKKLKSLRNKLSEYEMKKSMISWPLEEYEKLVEEEGMVFGEEEEDEDNKEEQFEYENQDESD", "length": 583 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTPAFDLSQDPDFLTIAIRVPYARVSEFDVYFEGSDFKFYAKPYFLRLTLPGRIVENGSEQGSYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRTAKPLVEEIGASEIPEEVVDDEEFDWEIEQTPCEEVSESALNPQCHYGFGNLRSGVLQRLQDELSDVIDIKDPDFTPAAERRQKRLAAELAKFDPDHYLADFFEDEAIEQILKYNPWWTDKYSKMMAFLEKSQEQENHATLVSFSEEEKYQLRKFVNKSYLLDKRACRQVCYSLIDILLAYCYETRVTEGEKNVESAWNIRKLSPTLCWFETWTNVHDIMVSFGRRVLCYPLYRHFKLVMKAYRDTIKILQLGKSAVLKCLLDIHKIFQENDPAYILNDLYISDYCVWIQKVKSKKLAALAEALKEVSLTKAQLGLELEELEAAALLVQEEETALKAAHSVSGQQTLCSSSEASDSEDSDSSVSSGNEDSGSDSEQDELKDSPSETVSSLQGPFLEESSAFLIVDGGVRRNTAIQESDASQGKPLASSWPLGVSGPLIEELGEQLKTTVQVSEPKGTTAVNRSNIQERDGCQTPNN", "length": 577 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMX5-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "Shq1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTPAFELTQDCDFLTVAIRVPHARASEFDVYFEGVDFKFYAKPYFLRLTLPGRIVENGSEQGTYDADKGIFTIRLPKETPGQHFEGLNMLTALLAPRKSRSAKPLVEEIGASGVAEEGADDEDEEFDWEIEQTPYEEVSESTLQSQCHYGFGNLRAGVVQRLQDELSEVIDIKDPDFTPVTERRQKRLAAELAKFDPDHYLADFFEDEAVEQILKYSPWWNDAHAEMVASLGKNQEQGDSAALVSFSEEEKYQLRKFVNKSYLLDKTAHRQVYYGLVDILLAYCYEVRVTEGEHSVESAWTIRKLSPTLCWFETWTDVHEILVSFGRRVLCYPLYRHFKLVLKAYRDTIKILQLGKSAVLKCLLDVHKVFQENDPAYILNDLYISDYCVWIQKAKSKKLAALTEALKAVSLSKAQLGLELPELEAAALLVQEEEGAGRAAQCNPSHQAPHSSPEPSDSDSTSSSGTEDSASEQEEPAGTQPSLLTSLQAPLLEEDSALIIRESGLCRNMASQGCEVSQGQPLASARAPLIEELGDALKMLRVSTPHGVSAGSHGSVEDAEERGQVPCD", "length": 569 }, "evidence": [ { "id": "A0A8V0ZCP4", "url": "https://omabrowser.org/oma/group/A0A8V0ZCP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "box H/ACA snoRNP assembly", "id": "GO:0000493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000493", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCP4" }, { "id": "PS51203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CS", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 89, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCQ6-1", "uniprot_ac": "A0A8V0ZCQ6", "uniprot_id": "A0A8V0ZCQ6_CHICK", "mass": { "chemical_mass": 92993.0, "monoisotopic_mass": 92993.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGEF16", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 16", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6", "locus": { "chromosome": "21", "start_pos": 1020082, "end_pos": 1028911, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021459", "url": "https://www.ensembl.org/id/ENSGALG00010021459" } ] } } ], "crossref": [ { "id": "A0A8V0ZCQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWRSRMLYVVFIWGAQRAVWLKRRWAGLAPSKERWSRVLEGLWGHQEPPSTLGVGAEAEHPSARSAPGLWGPSGSTLKRAVWDPQWYGDGQSERHRDSGVGSSRLPTQHCEPCRSCTLSLSRGQCLFPVCPSDCLSLAQLSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 832, "header": "tr|A0A8V0ZCQ6-1|A0A8V0ZCQ6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZCQ6-1", "sequence": { "sequence": "MQWRSRMLYVVFIWGAQRAVWLKRRWAGLAPSKERWSRVLEGLWGHQEPPSTLGVGAEAEHPSARSAPGLWGPSGSTLKRAVWDPQWYGDGQSERHRDSGVGSSRLPTQHCEPCRSCTLSLSRGQCLFPVCPSDCLSLAQLSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 832, "header": "tr|A0A8V0ZCQ6-1|A0A8V0ZCQ6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1027861, "end_pos": 1021237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052024.1", "url": "https://www.ensembl.org/id/ENSGALT00010052024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031053.1", "url": "https://www.ensembl.org/id/ENSGALP00010031053.1" } ] } }, { "isoform_ac": "A0A8V0ZIB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZIB0-1", "sequence": { "sequence": "MSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGEWGLHLWAWPR", "length": 650, "header": "tr|A0A8V0ZIB0-1|A0A8V0ZIB0_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1027417, "end_pos": 1021534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052035.1", "url": "https://www.ensembl.org/id/ENSGALT00010052035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031060.1", "url": "https://www.ensembl.org/id/ENSGALP00010031060.1" } ] } }, { "isoform_ac": "A0A8V0ZJU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZJU6-1", "sequence": { "sequence": "MGVDASGVLSTACSCETAELSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 711, "header": "tr|A0A8V0ZJU6-1|A0A8V0ZJU6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1028283, "end_pos": 1021237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052028.1", "url": "https://www.ensembl.org/id/ENSGALT00010052028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031057.1", "url": "https://www.ensembl.org/id/ENSGALP00010031057.1" } ] } }, { "isoform_ac": "A0A8V0ZJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZJV1-1", "sequence": { "sequence": "MLPQRQQQLSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 700, "header": "tr|A0A8V0ZJV1-1|A0A8V0ZJV1_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1028848, "end_pos": 1021237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052037.1", "url": "https://www.ensembl.org/id/ENSGALT00010052037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031062.1", "url": "https://www.ensembl.org/id/ENSGALP00010031062.1" } ] } }, { "isoform_ac": "A0A8V0ZJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZJX0-1", "sequence": { "sequence": "MEKQNALSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 698, "header": "tr|A0A8V0ZJX0-1|A0A8V0ZJX0_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1027856, "end_pos": 1021237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052020.1", "url": "https://www.ensembl.org/id/ENSGALT00010052020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031051.1", "url": "https://www.ensembl.org/id/ENSGALP00010031051.1" } ] } }, { "isoform_ac": "A0A8V0ZQP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6/entry#A0A8V0ZQP0-1", "sequence": { "sequence": "MVMVRASATGTAVWAPPGSPRSTLSAPCATAMSRSPPAAEDQTFLLEYRCHPLRSGPPAPTSPPGKRNPDPAMGCFPLAEPRRIVLSTDSPAALKVGTQQLIPRSLAVSTKTKNTTRNPSTGSIPEAACSGQKRASVPSVTVQGDTEEDGGGMLKRNLRNMSYRAAMKGAGTEMEPVSTVPTLKPMLEEGSAPPARSPGRSKRTLGRKRVQKHGGSFKDQPRLYQEIRERGLNSVSHESDEDLLEEPIPEEPSLPGAAIVVRSYRPAQVTWSQLPEVLEAGVLETITPEERKRQEAMFEIITSEFSYMHSLSVLVGCFKKSEELKETMTQTEHHHLFSNISDILAVSTSFFQALEKRHQENVLIPDISDIVEEHASKHFNPYISYCSNEVYQQRTLQRLLNTNPLFKEALKQIERKPECGGLPLISFLILPMQRVTRLPLLLDTVCQKTQACTAAYGAATRALKAISKLVKNCNEGARAMERTEQLCTLQKQLEFGKKKPFPLISASRWLLKRGELYLLSSEEGGIFRKGSGRVCHLFLFNDVLIITKKKSEESYTVMNYAMLDQVSVEKVETTEPPSPPPGRPGGHLLRVAMERDSEGRREEVMLSAETLSERARWVTALMHRERERPDSTPRGDLSQVEITRAYMAKQADEISLQQADVVLLLGEEDGWCWGERLRDGERGWFPQACARPITSRVAVECNVRRMERLRIETDV", "length": 715, "header": "tr|A0A8V0ZQP0-1|A0A8V0ZQP0_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 16 OS=Gallus gallus OX=9031 GN=ARHGEF16 PE=4 SV=1 CANONICAL=A0A8V0ZCQ6-1" }, "locus": { "chromosome": "21", "start_pos": 1027599, "end_pos": 1021237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052015.1", "url": "https://www.ensembl.org/id/ENSGALT00010052015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031049.1", "url": "https://www.ensembl.org/id/ENSGALP00010031049.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 178, "start_aa": "Thr", "end_pos": 178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr178", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419386", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QQ48-1", "protein_name": "Rho guanine nucleotide exchange factor 16 isoform X3", "gene_name": "Arhgef16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQRHSDSSLDEKLLEYRFHAELQLDANGNPMSGLPMVRGSLRARTNAAFEPEPSEPPQVPLEGEGSRPIILSTQSPAALKMGTQQLIPKSLAVASKAKTKSPARHQSFGAAVLSKEAARRDPRLFSTPSFSLDDMDVDASTAGNLKRNIRNQSYRAAMKGLGPPSSKGDSCQLGPKLQALAEEAAQPPARSPAKNKKTLGRKRAHKGSFKDDPQLYQEIRERGLNTSHESDDDILDEPSSPEATQRADTTIVVKSYRPAQLTWSQLPEVLESGVLDTLSVEERKRQEAIFEILTSEFSYLHSLSILVTEFLQSRELRATMTQTEHHHLFSNILDVLAASQKFFEALEQRHKAQVCVEDISDILEEHAEKHFHPYVAYCSNEVYQQRTLQKLSNSNTAFREALREIEKRPACGGLPMISFLILPMQRVTRLPLLTDTLCLKTQGHPERYKAASRALKAISKLVKQCNEGAHKMERTEQMYTLHTQLDFSKVNKSLPLISASRWLLKRGELFLLEESSIFRKIASRPTCYLFLFNDFLVVTKKKSEESYLVQDYAQLDHVQVRKLEASEPSLPGGSGRSSSVPHPFQVNLLHNSEGRQEQILLSSDSASDRARWITALTHKEREWQGITNKGELPQVEITKAYFAKQADEITLQQADVVLVLQEEDGWLHGERLRDGETGWFPESFARSITSRVAVEGNVRRMERLRVETDV", "length": 711 }, "evidence": [ { "id": "A0A8V0ZCQ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCQ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LKZ2-1", "protein_name": "Rho guanine nucleotide exchange factor 16", "gene_name": "ARHGEF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQRHSDSSLEEKLLEYRFHSELRLDAQGNPASTLPMVRGSLRSKSNAAFQPDSPEAQAPRAVVLSTQSPAALKMGTQQLIPRSLAVSSKAKTPARHQSFGAAMLSKEAARRDPRLLSAPSFSLDDMDVDTGSGGVLRRNLRNQSYRAAMKGLGTPGAGGGPVQLSPKLQALAEEPSQPPARYAAKNKKTLGRKRAHKGSFKDDPRLYQEIRERGLNTSHESDDDLLDETPSSEGPQKVDTPIVVKSYRPPQITWSQLPEVVELGILDKLPAEERKRQEAIFEILTSEFSYQHSLSILVAEFLQSRELRATMTQTEHHHLFSNITDVLSASQRFFEALEQRHKAQVCVEDISDILEEHAERHFHPYVIYCSNELYQQRALQRLTSSNAAFREALREIEQRPACGGLPMISFLILPMQRVTRLPLLADTLCLKTQGHPERYKAASRAFKAISKLVKQCNEGAHKMERTEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFVVEETGLFRKLASRPTCYLFLFNDVLVITKKKSEDSFVVQDYAQMDHIQVQKMEPSEASLPGGGSRSSSVPHPFQLTLLHNSEGRQEKILLSSDSASDRARWITALTYRERQGQGPSNKGDLLQVEVTKAYLAKQVDEITLQQADVVLILQQEDGWFYGERLRDGETGWFPEDFAQSITSRVAVEGNVRRMERLRVETDV", "length": 701 }, "evidence": [ { "id": "A0A8V0ZCQ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCQ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3U5C8-1", "protein_name": "Rho guanine nucleotide exchange factor 16", "gene_name": "Arhgef16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRHSDSSLDEKLLEYRFHAELRLDANGNPIPGLPMVRSSLKARANAAFEPDASEPLPPPPSPEDEEPPRPIVLSTQSPAALKMGTQQLIPKSLAVASKAKTKSPARHQSFGAAVLSKEAARRNPQLFSAPSFSLDDMDMDMVTTGNLRRNLRNQSYRAAMKGPGPPSSKGDSVQLGPKLQALAEEAAQPPSRYPAKNKKTLGRKRAHKGSFKDDPQLYQEIRERGLNTSHESDDDILDEPSGPVGTQRADTTIVVKSYRPAQLTWSQLPEVLESGVLDTLSTEERKRQEAIFEILTSEFSYLHSLSILVTEFLQSRELRATMTQTEHHHLFSNILDVMSASQKFFEALEQRHKAQVCVEDISDILEDHAQHHFHPYIAYCSNEVYQQRTLQKLSNSNAAFRDVLKEIEKRPACGGLPMISFLILPMQRVTRLPLLTDTLCLKTQGHPERYKAASQALKAISKLVKQCNEGAHKMERTEQIYTLNMQLDFGKVKSLPLISASRWLLKRGELFLLEESSIFRKIASRPTCYLFLFNDVLVVTKKKSEESYLVQDYAQLDHVQVRKLEPSEPLLPGGSSRSSSVPYPFQVNLLHNSEGRQEQILLSSDSASDRARWITALTYKERQWQGITNKGELPQVEVTKAYFAKQADEITLQQADIVLVLQEEDGWLHGERLRDGETGWFPESFAHSITSRVAVEGNVRRMERLRVETDV", "length": 713 }, "evidence": [ { "id": "A0A8V0ZCQ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VV41-1", "protein_name": "Rho guanine nucleotide exchange factor 16", "gene_name": "ARHGEF16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV", "length": 709 }, "evidence": [ { "id": "A0A8V0ZCQ6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "regulation of Cdc42 protein signal transduction", "id": "GO:0032489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032489", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 593, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 626, "end_pos": 743, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZCQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 752, "end_pos": 812, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 178 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 231, "end_pos": 233 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 456, "end_pos": 458 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCR6-1", "uniprot_ac": "A0A8V0ZCR6", "uniprot_id": "A0A8V0ZCR6_CHICK", "mass": { "chemical_mass": 164009.0, "monoisotopic_mass": 164009.0 }, "refseq": {}, "gene_names": [ { "name": "SETD5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ] } ], "protein_names": [ { "name": "SET domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SETD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6", "locus": { "chromosome": "12", "start_pos": 11600844, "end_pos": 11540401, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021462", "url": "https://www.ensembl.org/id/ENSGALG00010021462" } ] } } ], "crossref": [ { "id": "cd19181", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19181", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCR1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCR6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIB4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZJY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46462:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46462:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLNLKSWSPEEQLCGGSQPEPRFPHVRDVLAEALRLLSALGAASRCPLDSVIPDGRHEHCNPSGSHHTRYVLLRHGCRIGDHNYGAPPPPTPPASPPVQTIIPRAELNGLHSPDEENSGDSESSSEGESIPTWCHCSVSQDGFLLKCEKCRGMSRGKVIRLRRRKQDNVSGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVNRVRRTKPKKRKRSTEKARTAPKAKKIKAFREGSRKSLRMKNSPSEAHALDENTAEGWENRIRLWTDQYEEAFTNQYSADVQNLLERHLNSNKEYVGKTAMLDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHVIADGMIHLCIYAVATIAKDTEVTIAFDYEYNICNYKVDCACHKGNRNCPVQKRSPNAAEHLPPPVLGTLIGAETRRRKARRKELEMEQQGVVLDENISQQTEEVPEGPAAVSDNEVADKEEKQEEEKEESVDEQGTLAHSRRSREDRKVEAIMHMFENLEKRKRRREQPSDRNSTDAEVSINSEAPELEEVKTETPETEDASSTLSATAASNVSNSNISTGVNTRRSSQVADAVPEKTVTKPAPAKPSRPRPKSRFSRYRTSSAQRLRRQKQANSQQAELVQAVSEEGSAANLVTATDVTSVEGPGEGRQLMGSDPTVILAAGSQSNRTAVKYPKTKKYLVTEWLNDKAEKQECPIECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFNPERRRRPFLLDGIYSSCKKRWIKQALEEGMTQTSPAPQENRTQCLYQSNENSSSSSICKDDTDLLSPLKKWKSRYLMEQNVKKLLRPLSPVTPPPPVPSVPGSVSPQLATPCSSVPGEEESRNGYGVMFSPIPSLAASRCNTPLQFENVSSPESSPAHRPESMSPELCLRSDVDSSANTCPERPSLLSFGSSDLAPQPSINSTSETNFPGKSGEAQMLLRSSDQAFRTEFNLMYAFSPLNAMPRVDGLLRGSACLGDRKPVNSEAGCCSSPSEGYFSRHESGLLKETAHGSMSPCGERTCEGVRTAPQNPPQRKKVSLLEYRKRKQEAKEGGDSVRCTGTPTRQGSSGSGTDTDASSLPGSVVRTPSSPQSGFSPSHPSLPHVEDISPPDSRGASSSTSLCKSQENISSRWMVPTSVERLREGRGILEKVLRSGAKVSQRSEPSPTCDSAVERDADTAGGDTPEAHKGPAVYSPSRYSYQLLQSDSPQAESQTLLQQSSSPYRGHLTPSPGYSYRAAAQRTGHSLSHGSSETSLSSSSYSSPAHLVSTDSSALFAGNSGYYSSQQHSGSASSSLLKKSCPAAASPAQQMAVDSLSSESGSQPCTGASSSTSAPQSSRSLQSDLRTISLPSSGQSVLYQGSRGAVISSAQHYPHRGGSSVHQYRLQQLQGSGVKTQTGLS", "length": 1500, "header": "tr|A0A8V0ZCR6-1|A0A8V0ZCR6_CHICK Isoform 1 of SET domain containing 5 OS=Gallus gallus OX=9031 GN=SETD5 PE=4 SV=1 CANONICAL=A0A8V0ZCR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6/entry#A0A8V0ZCR1-1", "sequence": { "sequence": "MGFTSGPFCSPESVEASPAVSEKNVYSSHGYGATQKHSYRGLPYADHNYGAPPPPTPPASPPVQTIIPRAELNGLHSPDEENSGDSESSSEGESIPTWCHCSVSQDGFLLKCEKCRGMSRGKVIRLRRRKQDNVSGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVNRVRRTKPKKRKRSTEKARTAPKAKKIKAFREGSRKSLRMKNSPSEAHALDENTAEGWENRIRLWTDQYEEAFTNQYSADVQNLLERHLNSNKEYVGKTAMLDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHVIADGMIHLCIYAVATIAKDTEVTIAFDYEYNICNYKVDCACHKGNRNCPVQKRSPNAAEHLPPPVLGTLIGAETRRRKARRKELEMEQQGVVLDENISQQTEEVPEGPAAVSDNEVADKEEKQEEEKEESVDEQGTLAHSRRSREDRKVEAIMHMFENLEKRKRRREQPSDRNSTDAEVSINSEAPELEEVKTETPETEDASSTLSATAASNVSNSNISTGVNTRRSSQVADAVPEKTVTKPAPAKPSRPRPKSRFSRYRTSSAQRLRRQKQANSQQAELVQAVSEEGSAANLVTATDVTSVEGPGEGRQLMGSDPTVILAAGSQSNRTAVKYPKTKKYLVTEWLNDKAEKQECPIECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFNPERRRRPFLLDGIYSSCKKRWIKQALEEGMTQTSPAPQENRTQCLYQSNENSSSSSICKDDTDLLSPLKKWKSRYLMEQNVKKLLRPLSPVTPPPPVPSVPGSVSPQLATPCSSVPGEEESRNGYGVMFSPIPSLAASRCNTPLQFENVSSPESSPAHRPESMSPELCLRSDVDSSANTCPERPSLLSFGSSDLAPQPSINSTSETNFPGKSGEAQMLLRSSDQAFRTEFNLMYAFSPLNAMPRVDGLLRGSACLGDRKPVNSEAGCCSSPSEGYFSRHESGLLKETAHGSMSPCGERTCEGVRTAPQNPPQRKKVSLLEYRKRKQEAKEGGDSVRCTGTPTRQGSSGSGTDTDASSLPGSVVRTPSSPQSGFSPSHPSLPHVEDISPPDSRGASSSTSLCKSQENISSRWMVPTSVERLREGRGILEKVLRSGAKVSQRSEPSPTCDSAVERDADTAGGDTPEAHKGPAVYSPSRYSYQLLQSDSPQAESQTLLQQSSSPYRGHLTPSPGYSYRAAAQRTGHSLSHGSSETSLSSSSYSSPAHLVSTDSSALFAGNSGYYSSQQHSGSASSSLLKKSCPAAASPAQQMAVDSLSSESGSQPCTGASSSTSAPQSSRSLQSDLRTISLPSSGQSVLYQGSRGAVISSAQHYPHRGGSSVHQYRLQQLQGSGVKTQTGLS", "length": 1464, "header": "tr|A0A8V0ZCR1-1|A0A8V0ZCR6_CHICK Computationally mapped isoform of SET domain containing 5 OS=Gallus gallus OX=9031 GN=SETD5 PE=4 SV=1 CANONICAL=A0A8V0ZCR6-1" }, "locus": { "chromosome": "12", "start_pos": 11599204, "end_pos": 11565877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052031.1", "url": "https://www.ensembl.org/id/ENSGALT00010052031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031058.1", "url": "https://www.ensembl.org/id/ENSGALP00010031058.1" } ] } }, { "isoform_ac": "A0A8V0ZCR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6/entry#A0A8V0ZCR6-1", "sequence": { "sequence": "MSLNLKSWSPEEQLCGGSQPEPRFPHVRDVLAEALRLLSALGAASRCPLDSVIPDGRHEHCNPSGSHHTRYVLLRHGCRIGDHNYGAPPPPTPPASPPVQTIIPRAELNGLHSPDEENSGDSESSSEGESIPTWCHCSVSQDGFLLKCEKCRGMSRGKVIRLRRRKQDNVSGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVNRVRRTKPKKRKRSTEKARTAPKAKKIKAFREGSRKSLRMKNSPSEAHALDENTAEGWENRIRLWTDQYEEAFTNQYSADVQNLLERHLNSNKEYVGKTAMLDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHVIADGMIHLCIYAVATIAKDTEVTIAFDYEYNICNYKVDCACHKGNRNCPVQKRSPNAAEHLPPPVLGTLIGAETRRRKARRKELEMEQQGVVLDENISQQTEEVPEGPAAVSDNEVADKEEKQEEEKEESVDEQGTLAHSRRSREDRKVEAIMHMFENLEKRKRRREQPSDRNSTDAEVSINSEAPELEEVKTETPETEDASSTLSATAASNVSNSNISTGVNTRRSSQVADAVPEKTVTKPAPAKPSRPRPKSRFSRYRTSSAQRLRRQKQANSQQAELVQAVSEEGSAANLVTATDVTSVEGPGEGRQLMGSDPTVILAAGSQSNRTAVKYPKTKKYLVTEWLNDKAEKQECPIECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFNPERRRRPFLLDGIYSSCKKRWIKQALEEGMTQTSPAPQENRTQCLYQSNENSSSSSICKDDTDLLSPLKKWKSRYLMEQNVKKLLRPLSPVTPPPPVPSVPGSVSPQLATPCSSVPGEEESRNGYGVMFSPIPSLAASRCNTPLQFENVSSPESSPAHRPESMSPELCLRSDVDSSANTCPERPSLLSFGSSDLAPQPSINSTSETNFPGKSGEAQMLLRSSDQAFRTEFNLMYAFSPLNAMPRVDGLLRGSACLGDRKPVNSEAGCCSSPSEGYFSRHESGLLKETAHGSMSPCGERTCEGVRTAPQNPPQRKKVSLLEYRKRKQEAKEGGDSVRCTGTPTRQGSSGSGTDTDASSLPGSVVRTPSSPQSGFSPSHPSLPHVEDISPPDSRGASSSTSLCKSQENISSRWMVPTSVERLREGRGILEKVLRSGAKVSQRSEPSPTCDSAVERDADTAGGDTPEAHKGPAVYSPSRYSYQLLQSDSPQAESQTLLQQSSSPYRGHLTPSPGYSYRAAAQRTGHSLSHGSSETSLSSSSYSSPAHLVSTDSSALFAGNSGYYSSQQHSGSASSSLLKKSCPAAASPAQQMAVDSLSSESGSQPCTGASSSTSAPQSSRSLQSDLRTISLPSSGQSVLYQGSRGAVISSAQHYPHRGGSSVHQYRLQQLQGSGVKTQTGLS", "length": 1500, "header": "tr|A0A8V0ZCR6-1|A0A8V0ZCR6_CHICK Isoform 1 of SET domain containing 5 OS=Gallus gallus OX=9031 GN=SETD5 PE=4 SV=1 CANONICAL=A0A8V0ZCR6-1" }, "locus": { "chromosome": "12", "start_pos": 11599204, "end_pos": 11544374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052038.1", "url": "https://www.ensembl.org/id/ENSGALT00010052038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031063.1", "url": "https://www.ensembl.org/id/ENSGALP00010031063.1" } ] } }, { "isoform_ac": "A0A8V0ZIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6/entry#A0A8V0ZIB4-1", "sequence": { "sequence": "MSIAIPLGVTTPDTSYSDMAAGSDPESVEASPAVSEKNVYSSHGYGATQKHSYRGLPYADHNYGAPPPPTPPASPPVQTIIPRAELNGLHSPDEENSGDSESSSEGESIPTWCHCSVSQDGFLLKCEKCRGMSRGKVIRLRRRKQDNVSGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVNRVRRTKPKKRKRSTEKARTAPKAKKIKAFREGSRKSLRMKNSPSEAHALDENTAEGWENRIRLWTDQYEEAFTNQYSADVQNLLERHLNSNKEYVGKTAMLDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHVIADGMIHLCIYAVATIAKDTEVTIAFDYEYNICSNYKVDCACHKGNRNCPVQKRSPNAAEHLPPPVLGTLIGAETRRRKARRKELEMEQQGVVLDENISQQTEEVPEGPAAVSDNEVADKEEKQEEEKEESVDEQGTLAHSRRSREDRKVEAIMHMFENLEKRKRRREQPSDRNSTDAEVSINSEAPELEEVKTETPETEDASSTLSATAASNVSNSNISTGVNTRRSSQVADAVPEKTVTKPAPAKPSRPRPKSRFSRYRTSSAQRLRRQKQANSQQAELVQAVSEEGSAANLVTATDVTSVEGPGEGRQLMGSDPTVILAAGSQSNRTAVKYPKTKKYLVTEWLNDKAEKQECPIECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFNPERRRRPFLLDGIYSSCKKRWIKQALEEGMTQTSPAPQENRTQCLYQSNENSSSSSICKDDTDLLSPLKKWKSRYLMEQNVKKLLRPLSPVTPPPPVPSVPGSVSPQLATPCSSVPGEEESRNGYGVMFSPIPSLAASRCNTPLQFENVSSPESSPAHRPESMSPELCLRSDVDSSANTCPERPSLLSFGSSDLAPQPSINSTSETNFPGKSGEAQMLLRSSDQAFRTEFNLMYAFSPLNAMPRVDGLLRGSACLGDRKPVNSEAGCCSSPSEGYFSRHESGLLKETAHGSMSPCGERTCEGVRTAPQNPPQRKKVSLLEYRKRKQEAKEGGDSVRCTGTPTRQGSSGSGTDTDASSLPGSVVRTPSSPQSGFSPSHPSLPHVEDISPPDSRGASSSTSLCKSQENISSRWMVPTSVERLREGRGILEKVLRSGAKVSQRSEPSPTCDSAVERDADTAGGDTPEAHKGPAVYSPSRYSYQLLQSDSPQAESQTLLQQSSSPYRGHLTPSPGYSYRAAAQRTGHSLSHGSSETSLSSSSYSSPAHLVSTDSSALFAGNSGYYSSQQHSGSASSSLLKKSCPAAASPAQQMAVDSLSSESGSQPCTGASSSTSAPQSSRSLQSDLRTISLPSSGQSVLYQGSRGAVISSAQHYPHRGGSSVHQYRLQQLQGSGVKTQTGLS", "length": 1479, "header": "tr|A0A8V0ZIB4-1|A0A8V0ZIB4_CHICK Computationally mapped isoform of SET domain containing 5 OS=Gallus gallus OX=9031 GN=SETD5 PE=4 SV=1 CANONICAL=A0A8V0ZCR6-1" }, "locus": { "chromosome": "12", "start_pos": 11599204, "end_pos": 11562233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052040.1", "url": "https://www.ensembl.org/id/ENSGALT00010052040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031065.1", "url": "https://www.ensembl.org/id/ENSGALP00010031065.1" } ] } }, { "isoform_ac": "A0A8V0ZJY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6/entry#A0A8V0ZJY2-1", "sequence": { "sequence": "MCTPATAMGPPRNTAIAGCLTHIANTHFQDHNYGAPPPPTPPASPPVQTIIPRAELNGLHSPDEENSGDSESSSEGESIPTWCHCSVSQDGFLLKCEKCRGMSRGKVIRLRRRKQDNVSGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVNRVRRTKPKKRKRSTEKARTAPKAKKIKAFREGSRKSLRMKNSPSEAHALDENTAEGWENRIRLWTDQYEEAFTNQYSADVQNLLERHLNSNKEYVGKTAMLDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHVIADGMIHLCIYAVATIAKDTEVTIAFDYEYNICNYKVDCACHKGNRNCPVQKRSPNAAEHLPPPVLGTLIGAETRRRKARRKELEMEQQGVVLDENISQQTEEVPEGPAAVSDNEVADKEEKQEEEKEESVDEQGTLAHSRRSREDRKVEAIMHMFENLEKRKRRREQPSDRNSTDAEVSINSEAPELEEVKTETPETEDASSTLSATAASNVSNSNISTGVNTRRSSQVADAVPEKTVTKPAPAKPSRPRPKSRFSRYRTSSAQRLRRQKQANSQQAELVQAVSEEGSAANLVTATDVTSVEGPGEGRQLMGSDPTVILAAGSQSNRTAVKYPKTKKYLVTEWLNDKAEKQECPIECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFNPERRRRPFLLDGIYSSCKKRWIKQALEEGMTQTSPAPQENRTQCLYQSNENSSSSSICKDDTDLLSPLKKWKSRYLMEQNVKKLLRPLSPVTPPPPVPSVPGSVSPQLATPCSSVPGEEESRNGYGVMFSPIPSLAASRCNTPLQFENVSSPESSPAHRPESMSPELCLRSDVDSSANTCPERPSLLSFGSSDLAPQPSINSTSETNFPGKSGEAQMLLRSSDQAFRTEFNLMYAFSPLNAMPRVDGLLRGSACLGDRKPVNSEAGCCSSPSEGYFSRHESGLLKETAHGSMSPCGERTCEGVRTAPQNPPQRKKVSLLEYRKRKQEAKEGGDSVRCTGTPTRQGSSGSGTDTDASSLPGSVVRTPSSPQSGFSPSHPSLPHVEDISPPDSRGASSSTSLCKSQENISSRWMVPTSVERLREGRGILEKVLRSGAKVSQRSEPSPTCDSAVERDADTAGGDTPEAHKGPAVYSPSRYSYQLLQSDSPQAESQTLLQQSSSPYRGHLTPSPGYSYRAAAQRTGHSLSHGSSETSLSSSSYSSPAHLVSTDSSALFAGNSGYYSSQQHSGSASSSLLKKSCPAAASPAQQMAVDSLSSESGSQPCTGASSSTSAPQSSRSLQSDLRTISLPSSGQSVLYQGSRGAVISSAQHYPHRGGSSVHQYRLQQLQGSGVKTQTGLS", "length": 1448, "header": "tr|A0A8V0ZJY2-1|A0A8V0ZJY2_CHICK Computationally mapped isoform of SET domain containing 5 OS=Gallus gallus OX=9031 GN=SETD5 PE=4 SV=1 CANONICAL=A0A8V0ZCR6-1" }, "locus": { "chromosome": "12", "start_pos": 11599204, "end_pos": 11565947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052036.1", "url": "https://www.ensembl.org/id/ENSGALT00010052036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031061.1", "url": "https://www.ensembl.org/id/ENSGALP00010031061.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 913, "start_aa": "Thr", "end_pos": 913, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr913", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "Set3 complex", "id": "GO:0034967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034967", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "Rpd3L-Expanded complex", "id": "GO:0070210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070210", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": "GO:1902275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, 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This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999968.1. 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"Protein Classification" ] }, { "id": "A0A8V0ZJX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK66", "url": "https://www.orthodb.org/?gene=A0A8V0ZK66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK96", "url": "https://www.orthodb.org/?gene=A0A8V0ZK96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQU0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPEDIQRLLEDVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKPTRCPRRHPFLPAALTTSCVHTWHLKCPKARFSSRINLTEANSAASRLQF", "length": 370, "header": "tr|A0A8V0ZCY8-1|A0A8V0ZCY8_CHICK Isoform 1 of Src kinase associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=4 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZCX5-1", "sequence": { "sequence": "MHVVQGWKVSAVRLPLRCDGAAGIAACTFGLGTYSFLLGTRRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 340, "header": "tr|A0A8V0ZCX5-1|A0A8V0ZCY8_CHICK Computationally mapped isoform of Src kinase associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=4 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3559977, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052118.1", "url": "https://www.ensembl.org/id/ENSGALT00010052118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031123.1", "url": "https://www.ensembl.org/id/ENSGALP00010031123.1" } ] } }, { "isoform_ac": "A0A8V0ZCY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZCY8-1", "sequence": { "sequence": "MIPEDIQRLLEDVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKPTRCPRRHPFLPAALTTSCVHTWHLKCPKARFSSRINLTEANSAASRLQF", "length": 370, "header": "tr|A0A8V0ZCY8-1|A0A8V0ZCY8_CHICK Isoform 1 of Src kinase associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=4 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3649289, "end_pos": 3535573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052139.1", "url": "https://www.ensembl.org/id/ENSGALT00010052139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031138.1", "url": "https://www.ensembl.org/id/ENSGALP00010031138.1" } ] } }, { "isoform_ac": "A0A8V0ZD16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZD16-1", "sequence": { "sequence": "MIPEDIQRLLEDVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 353, "header": "tr|A0A8V0ZD16-1|A0A8V0ZD16_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3535573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052193.1", "url": "https://www.ensembl.org/id/ENSGALT00010052193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031169.1", "url": "https://www.ensembl.org/id/ENSGALP00010031169.1" } ] } }, { "isoform_ac": "A0A8V0ZIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZIP0-1", "sequence": { "sequence": "MCHLHHRGTGGTRQWGPTEMPCCYQKPLHSIRSNIYISTHLLASKKPSRQRKCSMSGRYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 364, "header": "tr|A0A8V0ZIP0-1|A0A8V0ZIP0_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3531523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052252.1", "url": "https://www.ensembl.org/id/ENSGALT00010052252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031215.1", "url": "https://www.ensembl.org/id/ENSGALP00010031215.1" } ] } }, { "isoform_ac": "A0A8V0ZJX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZJX6-1", "sequence": { "sequence": "MIPEDIQRLLEDVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDVRFAVAPHQTLSEASRYIASSTLPFVC", "length": 121, "header": "tr|A0A8V0ZJX6-1|A0A8V0ZJX6_CHICK Computationally mapped isoform of Src kinase associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=4 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3570222, "end_pos": 3535573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052075.1", "url": "https://www.ensembl.org/id/ENSGALT00010052075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031087.1", "url": "https://www.ensembl.org/id/ENSGALP00010031087.1" } ] } }, { "isoform_ac": "A0A8V0ZK66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZK66-1", "sequence": { "sequence": "MIPEDIQRLLEDVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 334, "header": "tr|A0A8V0ZK66-1|A0A8V0ZK66_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3535573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052211.1", "url": "https://www.ensembl.org/id/ENSGALT00010052211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031184.1", "url": "https://www.ensembl.org/id/ENSGALP00010031184.1" } ] } }, { "isoform_ac": "A0A8V0ZK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZK96-1", "sequence": { "sequence": "MKRKHVECFLVDGLQNENLSPKAREQRNAILFGFQQVKARYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 346, "header": "tr|A0A8V0ZK96-1|A0A8V0ZK96_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3528908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052257.1", "url": "https://www.ensembl.org/id/ENSGALT00010052257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031217.1", "url": "https://www.ensembl.org/id/ENSGALP00010031217.1" } ] } }, { "isoform_ac": "A0A8V0ZQU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZQU0-1", "sequence": { "sequence": "MEQSLGPNCQSFHFQPPPRVPSISAHTQHGFPLQQKYAALALSDSSSLITHPRENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 350, "header": "tr|A0A8V0ZQU0-1|A0A8V0ZQU0_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3560763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052087.1", "url": "https://www.ensembl.org/id/ENSGALT00010052087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031099.1", "url": "https://www.ensembl.org/id/ENSGALP00010031099.1" } ] } }, { "isoform_ac": "A0A8V0ZQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8/entry#A0A8V0ZQX1-1", "sequence": { "sequence": "MEDFFPPWGISFHHGHPYGGCVCVQTSEHEMLCVRSLLGRRCCCTPLWAFRYHLEFLPRGENQHDAGFGQDSSDDNQSWSLAPSMTSDVSLPSDLQDDGMEEITLRPVEDTGNILKQGYLEKRSRDHSFFGSEWQKRWCVLNRKTFHYYANEKSKQPKGTFSIEHYSARLALHLRKDSRRSCCFELVCPGKRTYEFTAPSPAEAKDWVDQIQFLLKDLSSLTIPYDEEEEELYNDVGSSDSMTTASHNTTLNQDDGMEEDDIYEVFPEEDPNAPEDSGDDGSGQHRGRSRRDYANYYQGVWDCSAEHPNELSFHRGDLIYILSKEYNMYGWWVGELNSTVGIVPKDYLAAAYDLEER", "length": 357, "header": "tr|A0A8V0ZQX1-1|A0A8V0ZQX1_CHICK Computationally mapped isoform of Src kinase-associated phosphoprotein 1 OS=Gallus gallus OX=9031 GN=SKAP1 PE=3 SV=1 CANONICAL=A0A8V0ZCY8-1" }, "locus": { "chromosome": "27", "start_pos": 3659947, "end_pos": 3549299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052131.1", "url": "https://www.ensembl.org/id/ENSGALT00010052131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031134.1", "url": "https://www.ensembl.org/id/ENSGALP00010031134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BD43-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "SKAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQAAVALPEEICWLLEDAEEFLAEGLRNENLSALARDHRDHILRGFQQIKSRYFWDFQPQGGDQAENYLGQDSSDDNHSGTHGPSFTSDAAFLPDYQDEGMEDITRGAQELDNIIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYTVRMAPYLRKDSKKECCFELTSQDRRSYEFTASNPAEARDWVDQISFLLKDLSSLTIPCEEEEEEGEEEEEEMYDDIDGFDSSNSGSQSRPIMLPGSMGLKEPTEEKEEDDIYEVLPDEELGLEEDENGTQQKGVDYANYYQGLWDCHGDQPDELSFQRGDIIRILSKEYNMYGWWVGEMNSLIGIVPKEYLTTAFEVEER", "length": 367 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TGP3-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "SKAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQAAAALPEEIRWLLEDTEDFLAEGLRNENLSAGAKDNRDHILRGLQQIKARYFWNFQPQGGDQPENYLGQDSSDDNHSGTHGPSFTSDAPFLSDYQDEGMEDIERGAQELDNIIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGIFLIKGYSVRMAPYLRKDYKKEYCFELTSQDRRSYEFTASSPAEARDWVNQISFLLKDLSSLTIPYEEEEEKEEEEEMYDDIDGFDSSNSGSQSRPIVLPGSVGLKEAMEEKEDDIYEILPEEEHDLEEDESGTQQKGVDYASYYQGLWDCHGDQSDELSFQRGDLIRILSKEYSMYGWWVGELNSLIGIVPKEYLTTAFEVEER", "length": 364 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1R4C0-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "skap1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTAVDDIRQLLRDCELFVFEILHDENLSIAARESREILQRNFVVVQKRHPQEFPHRLESNPEDSSDDNRSSSLGRSAPSDDMSVASDYQEEGGSELFEEIPLVAAQDLSNILKQGYLEKKRRDHSFFSMEWQKRWCVLNNTIFYYFGSDKDKQQKGSFYINGYSAELVPSLRKDSKKSSCFEMSAPGRRSYQFTASSPREAREWVDQINFVLKDLSSNFIPFDDDEEEEEVEEEEETYDDIERATTPPPPRPGVASAQVTTPRKTQNSHEEWKDQALPQEDEEDDEEEDIYEILPDDENSDNAEDCSERTGSSDYANYYQGLWDCEAEGPDELAFQRGDLIYILSKEYNIYGWWVGELDGAIGIVPKEFLHPAYIL", "length": 377 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UUV5-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "Skap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQAVALPEEICWLLEDTEDFLAEGLQNENLSPGAQDQRAHILRGFQQIKSRYCWDFQPQGGDLGQDGSDDNLSGTHGPPLTSEASFWSDYQDEGIEDILRGAQELDSVIKQGYLEKKSKDHSFFGSEWQKRWCVISRGLFLYYANEKSKQPKGTFLIKGYSVRMAPHLRKDSKKESCFELISQDRRSYEFTASSPAEARDWVDQISFLLKDLSSLTIPFEEEEEEEEEEEKEEEEMYNDVDGFDSPRSGSQCRAMALPEPTEKEEDIYEVLPDDDDLEEDTCGAHRRRVDYADYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSVIGIVPKDYLTTAFEMEGI", "length": 355 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V7G1-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "Skap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAIALPEEICWLLEDAEDFLAEGLQNENLSPGAQDQRDHILRGFQQIKSRYCWDFQPQGDDLGQDGSDENLSGTHGPALASDASFWSDYQEEGIDDIIRGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVISRGLFLYYANEKSKQPKGTFLIKGYNVRMAPHLRKDSKKDSCFELTSQDRRSYEFTAFSPAEARDWVDQISFLLKDLSSLTIPFEEEEEEEEEDKEQEEMYNDIDGFDSARSGSQGRAMALPEPLDKEEDVYEVLPDEDDLEEDACGAHRRRVDYADYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSIIGIVPKDYLTTAFEMEGR", "length": 354 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86WV1-1", "protein_name": "Src kinase-associated phosphoprotein 1", "gene_name": "SKAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER", "length": 359 }, "evidence": [ { "id": "A0A8V0ZCY8", "url": "https://omabrowser.org/oma/group/A0A8V0ZCY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of adaptive immune response", "id": "GO:0002821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of integrin activation", "id": "GO:0033625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of cell-cell adhesion mediated by integrin", "id": "GO:0033634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of heterotypic cell-cell adhesion", "id": "GO:0034116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of cell-matrix adhesion", "id": "GO:0001954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "positive regulation of leukocyte cell-cell adhesion", "id": "GO:1903039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 212, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCX6-1", "uniprot_ac": "A0A8V0ZCX6", "uniprot_id": "A0A8V0ZCX6_CHICK", "mass": { "chemical_mass": 185486.0, "monoisotopic_mass": 185486.0 }, "refseq": { "ac": "XP_015152498", "name": "rootletin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152498" }, "gene_names": [ { "name": "CROCC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ] }, { "name": "CROCC", "type": "synonym", "evidence": [ { "id": "XP_015152498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152498" } ] } ], "protein_names": [ { "name": "Ciliary rootlet coiled-coil, rootletin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6/entry#names_and_taxonomy" } ] }, { "name": "rootletin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152498" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152498.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152498" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CROCC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6", "locus": { "chromosome": "21", "start_pos": 4404312, "end_pos": 4389068, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020351", "url": "https://www.ensembl.org/id/ENSGALG00010020351" } ] } } ], "crossref": [ { "id": "428191", "url": "https://www.ncbi.nlm.nih.gov/gene/428191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428191", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AGIQMDG", "url": "https://omabrowser.org/oma/group/AGIQMDG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDZ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLLSLQEENRILQQELSRVEDLLAQSRAERDELAIKYNAISERLEQSLRLEAGDQEAAESRSLAQHNIELRRLLDEEQAAYKRKLQAYQEGQQRQAQLVQKLQAKVLQYKKKCGEVEQQLLKKETELEQERLTSQPEEESPNELENALIRLEEEQQRSCSLVQVNSMLREQLEQANVANAALSEDIRKLTADWARARGELEQREAQWRREEESFNTYFSNEHGRLLTLWRQAVAFRRHFGQLRASTERDLAELGQEVSRAGRAAHAACMQLGAHLQLAEGRAGAVQEQQAQQLAQLEEHLAARGRDAERERAVLGDRLAELTAALQQLREEGGEKERAVQALTAQLQKMEASRAQEPSAEEVQALRAELELLHQTLQDITQAVLADDHGSPQGPPRLSCRSLSPAAAAATLGAVHGALRRRHIQLQEAREVSGNLRRELGDSESRRAALEQRLEQLSTEAEGCRQAQDEAVREAARLRADTELLRSEQGRMEQALVAEQARAGALQRSEAELQLRVRELEEQRDEANRAAEAARQQLKHSTQQMEQLEGQRAAGQQELLRAREALSRAQLEAEVARGEQAALGEALAQAQGSGAELEAALRDARTQEARLRDAAARSSELAASLARDKRELSRALVGLEEQHEADSEARRELEGLKAELERLERSCRDGEAERMELERARRAAERSCEGLRAELRELRGELQRMREQLGQVQQEQRAAGEALVQAQGEQQRLSAELERTMQEREGLAKEGASLGVQLHAAQRDARDRAQEADGLRAEKAVLETNLFEAQERLGQLNTCRQQLEAEKQSLRVARDGLLEELGAVRQRLAVAQEEVVALHRTQEEHMGELKQLRREKEELDVERGRLAREQQELAAELASARQQRDEGVLRAESEKQQALALKEEEKAALAGTLAGLQQSLAQATAELERQRHENASWQQQQQHRLAELRALQAQLEAAEEAHAREATALREQAVTASQQRDSALRDVEEARVQLALEAEARAAGQQALLRAQREAQEGREGREEQRRMGMEARRALGDAAREQEALRRSNEQLRAALRHSEGQRISLQRAAEQQEQRLALAEDGQAAAGREAAELRATLRGLERDRLDARRELQELRRQVKALDSENSKKSKEVEELRARVAREEQHEEERHREAFGLRRKVVESEAGVEATRKELQQLQRRLAEKEADFQQRERALSRSLEDSRGHEKKLLADARNLRLKAEAARGEAAELSLKLSAAEGRAQGLEAELARGEERRRDAEMRLSGLSSALRCTVGVGRAHGSSAGKAGPRKETQTSCSPPDPDAAADPEAVRAALQDFLRQLQDAQRDKEELQVRVCSLSKQLAEAEAQRDRALRLQKQLAESKEGWQGSESKQAALLLQEEMLQQGEGERRLLLEKVSALERSLHAAEGERRAAQEKLSALLAAKDHAQGTAGANTSTALQQRLQKLQTALAAGELDRRALQEMLDAAREERGVLREQLRALQEERAVLELRREELEAQVQQLQETQRQQDEEEEAVLGGLRAEQWGLQERVGSLQRAVTQLEAERREAERSALRLEKDNCALKRTLEKVEREKLKTHEASLRLALQKGRLDRSLGTSEQQLAEAQRRIQVLQAQVSALEQSSGASQEPPAQQRGAQESRRHPRSI", "length": 1649, "header": "tr|A0A8V0ZCX6-1|A0A8V0ZCX6_CHICK Isoform 1 of Ciliary rootlet coiled-coil, rootletin OS=Gallus gallus OX=9031 GN=CROCC PE=1 SV=1 CANONICAL=A0A8V0ZCX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6/entry#A0A8V0ZCX6-1", "sequence": { "sequence": "MASLLSLQEENRILQQELSRVEDLLAQSRAERDELAIKYNAISERLEQSLRLEAGDQEAAESRSLAQHNIELRRLLDEEQAAYKRKLQAYQEGQQRQAQLVQKLQAKVLQYKKKCGEVEQQLLKKETELEQERLTSQPEEESPNELENALIRLEEEQQRSCSLVQVNSMLREQLEQANVANAALSEDIRKLTADWARARGELEQREAQWRREEESFNTYFSNEHGRLLTLWRQAVAFRRHFGQLRASTERDLAELGQEVSRAGRAAHAACMQLGAHLQLAEGRAGAVQEQQAQQLAQLEEHLAARGRDAERERAVLGDRLAELTAALQQLREEGGEKERAVQALTAQLQKMEASRAQEPSAEEVQALRAELELLHQTLQDITQAVLADDHGSPQGPPRLSCRSLSPAAAAATLGAVHGALRRRHIQLQEAREVSGNLRRELGDSESRRAALEQRLEQLSTEAEGCRQAQDEAVREAARLRADTELLRSEQGRMEQALVAEQARAGALQRSEAELQLRVRELEEQRDEANRAAEAARQQLKHSTQQMEQLEGQRAAGQQELLRAREALSRAQLEAEVARGEQAALGEALAQAQGSGAELEAALRDARTQEARLRDAAARSSELAASLARDKRELSRALVGLEEQHEADSEARRELEGLKAELERLERSCRDGEAERMELERARRAAERSCEGLRAELRELRGELQRMREQLGQVQQEQRAAGEALVQAQGEQQRLSAELERTMQEREGLAKEGASLGVQLHAAQRDARDRAQEADGLRAEKAVLETNLFEAQERLGQLNTCRQQLEAEKQSLRVARDGLLEELGAVRQRLAVAQEEVVALHRTQEEHMGELKQLRREKEELDVERGRLAREQQELAAELASARQQRDEGVLRAESEKQQALALKEEEKAALAGTLAGLQQSLAQATAELERQRHENASWQQQQQHRLAELRALQAQLEAAEEAHAREATALREQAVTASQQRDSALRDVEEARVQLALEAEARAAGQQALLRAQREAQEGREGREEQRRMGMEARRALGDAAREQEALRRSNEQLRAALRHSEGQRISLQRAAEQQEQRLALAEDGQAAAGREAAELRATLRGLERDRLDARRELQELRRQVKALDSENSKKSKEVEELRARVAREEQHEEERHREAFGLRRKVVESEAGVEATRKELQQLQRRLAEKEADFQQRERALSRSLEDSRGHEKKLLADARNLRLKAEAARGEAAELSLKLSAAEGRAQGLEAELARGEERRRDAEMRLSGLSSALRCTVGVGRAHGSSAGKAGPRKETQTSCSPPDPDAAADPEAVRAALQDFLRQLQDAQRDKEELQVRVCSLSKQLAEAEAQRDRALRLQKQLAESKEGWQGSESKQAALLLQEEMLQQGEGERRLLLEKVSALERSLHAAEGERRAAQEKLSALLAAKDHAQGTAGANTSTALQQRLQKLQTALAAGELDRRALQEMLDAAREERGVLREQLRALQEERAVLELRREELEAQVQQLQETQRQQDEEEEAVLGGLRAEQWGLQERVGSLQRAVTQLEAERREAERSALRLEKDNCALKRTLEKVEREKLKTHEASLRLALQKGRLDRSLGTSEQQLAEAQRRIQVLQAQVSALEQSSGASQEPPAQQRGAQESRRHPRSI", "length": 1649, "header": "tr|A0A8V0ZCX6-1|A0A8V0ZCX6_CHICK Isoform 1 of Ciliary rootlet coiled-coil, rootletin OS=Gallus gallus OX=9031 GN=CROCC PE=1 SV=1 CANONICAL=A0A8V0ZCX6-1" }, "locus": { "chromosome": "21", "start_pos": 4403903, "end_pos": 4389085, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049163.1", "url": "https://www.ensembl.org/id/ENSGALT00010049163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029067.1", "url": "https://www.ensembl.org/id/ENSGALP00010029067.1" } ] } }, { "isoform_ac": "A0A8V0ZDZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6/entry#A0A8V0ZDZ3-1", "sequence": { "sequence": "MASLLSLQEENRILQQELSRVEDLLAQSRAERDELAIKYNAISERLEQSLRLEAGDQEAAESRSLAQHNIELRRLLDEEQAAYKRKLQAYQEGQQRQAQLVQKLQAKVLQYKKKCGEVEQQLLKKETELEQERLTSQPEEESPNELENALIRLEEEQQRSCSLVQVNSMLREQLEQANVANAALSEDIRKLTADWARARGELEQREAQWRREEESFNTYFSNEHGRLLTLWRQAVAFRRHFGQLRASTERDLAELGQEVSRAGRAAHAACMQLGAHLQLAEGRAGAVQEQQAQQLAQLEEHLAARGRDAERERAVLGDRLAELTAALQQLREEGGEKERAVQALTAQLQKMEASRAQEPSAEEVQALRAELELLHQTLQDITQAVLADDHGSPQGPPRLSCRSLSPAAAAATLGAVHGALRRRHIQLQEAREVSGNLRRELGDSESRRAALEQRLEQLSTEAEGCRQAQDEAVREAARLRADTELLRSEQGRMEQALVAEQARAGALQRSEAELQLRVRELEEQRDEANRAAEAARQQLKHSTQQMEQLEGQRAAGQQELLRAREALSRAQLEAEVARGEQAALGEALAQAQGSGAELEAALRDARTQEARLRDAAARSSELAASLARDKRELSRALVGLEEQHEADSEARRELEGLKAELERLERSCRDGEAERMELERARRAAERSCEGLRAELRELRGELQRMREQLGQVQQEQRAAGEALVQAQGEQQRLSAELERTMQEREGLAKEGASLGVQLHAAQRDARDRAQEADGLRAEKAVLETNLFEAQERLGQLNTCRQQLEAEKQSLRVARDGLLEELGAVRQRLAVAQEEVVALHRTQEEHMGELKQLRREKEELDVERGRLAREQQELAAELASARQQRDEGVLRAESEKQQALALKEEEKAALAGTLAGLQQSLAQATAELERQRHENASWQQQQQHRLAELRALQAQLEAAEEAHAREATALREQAVTASQQRDSALRDVEEARVQLALEAEARAAGQQALLRAQREAQEGREGREEQRRMGMEARRALGDAAREQEALRRSNEQLRAALRHSEGQRISLQRAAEQQEQRLALAEDGQAAAGREAAELRATLRGLERDRLDARRELQELRRQVKALDSENSKKSKEVEELRARVAREEQHEEERHREAFGLRRKVVESEAGVEATRKELQQLQRRLAEKEADFQQRERALSRSLEDSRGHEKKLLADARNLRLKAEAARGEAAELSLKLSAAEGRAQGLEAELARGEERRRDAEMRLSGLSSALRCTVGVGRAHGSSAGKAGPRKETQTSCSPPDPDAAADPEAVRAALQDFLRQLQDAQRDKEELQVRVCSLSKQLAEAEAQRDRALRLQKQLAESKEGWQGSESKQAALLLQEEMLQQGEGERRLLLEKVSALERSLHAAEGERRAAQEKLSALLAAKDHAQGTAGANTSTALQQRLQKLQTALAAGELDRRALQEMLDAAREERGVLREQLRALQEERAVLELRREELEAQVQQLQETQRQQDEEEEAVLGGLRAEQWGLQERVGSLQRAVTQLEAERREAERSALRLEKDNCALKRTLEKVEREKLKTHEASLRLALQKGRLDRSLGTSEQQLAEAQRRIQVLQAGGTGALPAP", "length": 1626, "header": "tr|A0A8V0ZDZ3-1|A0A8V0ZDZ3_CHICK Computationally mapped isoform of Ciliary rootlet coiled-coil, rootletin OS=Gallus gallus OX=9031 GN=CROCC PE=1 SV=1 CANONICAL=A0A8V0ZCX6-1" }, "locus": { "chromosome": "21", "start_pos": 4403669, "end_pos": 4389085, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049167.1", "url": "https://www.ensembl.org/id/ENSGALT00010049167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029069.1", "url": "https://www.ensembl.org/id/ENSGALP00010029069.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428191", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428191", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5TZA2-1", "protein_name": "Rootletin", "gene_name": "CROCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLGLAGAQEVELTLETVIQTLESSVLCQEKGLGARDLAQDAQITSLPALIREIVTRNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRRSSAPFSPPSGPPEK", "length": 2017 }, "evidence": [ { "id": "A0A8V0ZCX6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VCD1-1", "protein_name": "Rootletin, isoform E", "gene_name": "Root", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQAYRDNFKQTPCPSAVDLQAAGPAHQSATASRLPFSRSQRGRDPSASGASVSASVAGGLTPRMMSPGPPGAGGGGGGGVSGGGSGDPSALLRQNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKPTAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVGKDINGSNATVAFAVQQAKRAADDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAVVQDAENADREADAEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYDVGGGNAGGGSFNCGLDHSVIEQETRDLRLKVRRLETLLAEKESELARCKARMNDSAKCHDGLDGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQHLRSTLGDSLRNVSQHPVDPHLLESESRRLDSAVSMSLPPSSCRDYDRD", "length": 2048 }, "evidence": [ { "id": "A0A8V0ZCX6", "url": "https://omabrowser.org/oma/group/A0A8V0ZCX6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "ciliary rootlet", "id": "GO:0035253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "subapical part of cell", "id": "GO:0120219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cilium", "id": "GO:1903566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1438, "end_pos": 1440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX6" }, { "id": "PF15035", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rootletin-like coiled-coil", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 262, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1438, "end_pos": 1440 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCX7-1", "uniprot_ac": "A0A8V0ZCX7", "uniprot_id": "A0A8V0ZCX7_CHICK", "mass": { "chemical_mass": 16159.0, "monoisotopic_mass": 16159.0 }, "refseq": { "ac": "NP_001264838", "name": "grifin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" }, "gene_names": [ { "name": "GRIFIN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7" } ] }, { "name": "GRIFIN", "type": "synonym", "evidence": [ { "id": "NP_001264838", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" } ] } ], "protein_names": [ { "name": "Galectin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7/entry#names_and_taxonomy" } ] }, { "name": "grifin", "type": "synonym", "evidence": [ { "id": "NP_001264838", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01009570.1, BU224746.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Dec 3, 2021 this sequence version replaced NP_001264838.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" } ] }, { "annotation": "Data indicate restriction of expression of galectin-related inter-fiber protein (GRIFIN) to the lens.", "evidence": [ { "database": "RefSeq", "id": "NP_001264838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" }, { "database": "PubMed", "id": "27296808", "url": "https://glygen.org/publication/PubMed/27296808" } ] }, { "annotation": "On the level of gene expression, GRIFIN's promoter was activated by transcription factor L-Maf alone and together with Pax6 like a crystallin gene, substantiating C-GRIFIN's status as lens-specific galectin.", "evidence": [ { "database": "RefSeq", "id": "NP_001264838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" }, { "database": "PubMed", "id": "30328540", "url": "https://glygen.org/publication/PubMed/30328540" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRIFIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7", "locus": { "chromosome": "14", "start_pos": 3180412, "end_pos": 3182665, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020045", "url": "https://www.ensembl.org/id/ENSGALG00010020045" } ] } } ], "crossref": [ { "id": "A0A8V0ZCX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427660", "url": "https://www.ncbi.nlm.nih.gov/gene/427660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346", "url": 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"MALRFEALYPEGMCPGWSVVVKGETSSSTSMFEINFLSHPGDQIAFHFNPRFASSRIVCNSFLANHWGKEEVNKTFPFEAKEPFQVEIYSDQDYFHIFIDENKILQYKHRQKQLSSITKLQILNDIEISSVEITKRGLY", "length": 139, "header": "tr|A0A8V0ZCX7-1|A0A8V0ZCX7_CHICK Isoform 1 of Galectin OS=Gallus gallus OX=9031 GN=GRIFIN PE=4 SV=1 CANONICAL=A0A8V0ZCX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7/entry#A0A8V0ZCX7-1", "sequence": { "sequence": "MALRFEALYPEGMCPGWSVVVKGETSSSTSMFEINFLSHPGDQIAFHFNPRFASSRIVCNSFLANHWGKEEVNKTFPFEAKEPFQVEIYSDQDYFHIFIDENKILQYKHRQKQLSSITKLQILNDIEISSVEITKRGLY", "length": 139, "header": "tr|A0A8V0ZCX7-1|A0A8V0ZCX7_CHICK Isoform 1 of Galectin OS=Gallus gallus OX=9031 GN=GRIFIN PE=4 SV=1 CANONICAL=A0A8V0ZCX7-1" }, "locus": { "chromosome": "14", "start_pos": 3182636, "end_pos": 3180905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048429.1", "url": "https://www.ensembl.org/id/ENSGALT00010048429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028552.1", "url": "https://www.ensembl.org/id/ENSGALP00010028552.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken GRIFIN: A homodimeric member of the galectin network with canonical properties and a unique expression profile.", "journal": "Biochimie", "date": "2016", "authors": "Garc\u00eda Caballero Gabriel, Kaltner Herbert, Michalak Malwina, Shilova Nadezhda, Yegres Michelle, Andr\u00e9 Sabine, Ludwig Anna-Kristin, Manning Joachim C, Schmidt Sebastian, Schn\u00f6lzer Martina, Bovin Nicolai V, Reusch Dietmar, Kopitz J\u00fcrgen, Gabius Hans-Joachim", "evidence": [ { "database": "RefSeq", "id": "NP_001264838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" } ], "reference": [ { "type": "PubMed", "id": "27296808", "url": "https://glygen.org/publication/PubMed/27296808" } ] }, { "title": "Chicken GRIFIN: binding partners, developmental course of localization and activation of its lens-specific gene expression by L-Maf/Pax6.", "journal": "Cell and tissue research", "date": "2019-03", "authors": "Garc\u00eda Caballero Gabriel, Schmidt Sebastian, Schn\u00f6lzer Martina, Schl\u00f6tzer-Schrehardt Ursula, Knospe Clemens, Ludwig Anna-Kristin, Manning Joachim C, Muschler Paul, Kaltner Herbert, Kopitz J\u00fcrgen, Gabius Hans-Joachim", "evidence": [ { "database": "RefSeq", "id": "NP_001264838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264838" } ], "reference": [ { "type": "PubMed", "id": "30328540", "url": "https://glygen.org/publication/PubMed/30328540" } ] } ], "pathway": [ { "id": "gga:427660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427660", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX7" }, { "id": "PS51304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galectin", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 134, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"https://www.orthodb.org/?gene=A0A8V0ZJH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWP1", "url": "https://www.orthodb.org/?gene=E1BWP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39299:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39299:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWP1", "url": "https://www.uniprot.org/uniprotkb/E1BWP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWP1-1", "url": "https://www.uniprot.org/uniprotkb/E1BWP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSLPFSQGSTALLVHQPICFNAFLRDSKQVKQHYEFKHSLPLQIKPCSELSFPVKIYFCVTILSLLSVIGLTIETLVRQTEEDFTISLIQLVGVVFCVYYVTRGILQENRQELIVFVLSILLVMFRSIINFTVLPAEQKPKLLARFILILLVGSFDVICAIILIQSQSMMAFRVGGALESLQSQYFMLNLCFSMLTFDLQAQLCLCILLISLHEITLLHNIISATGVLWACLKVTVSIIAILKELKPLVWIFLCQNVPEVVFLIYLLYTVIKEWGRGNSYTLEAAFITGSCISVAIKSVLFWALIHVYRGFGQGLRERMFSSYGRIDS", "length": 329, "header": "tr|A0A8V0ZCY0-1|A0A8V0ZCY0_CHICK Isoform 1 of DUF7789 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC419404 PE=4 SV=1 CANONICAL=A0A8V0ZCY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0/entry#A0A8V0ZCY0-1", "sequence": { "sequence": "MVSLPFSQGSTALLVHQPICFNAFLRDSKQVKQHYEFKHSLPLQIKPCSELSFPVKIYFCVTILSLLSVIGLTIETLVRQTEEDFTISLIQLVGVVFCVYYVTRGILQENRQELIVFVLSILLVMFRSIINFTVLPAEQKPKLLARFILILLVGSFDVICAIILIQSQSMMAFRVGGALESLQSQYFMLNLCFSMLTFDLQAQLCLCILLISLHEITLLHNIISATGVLWACLKVTVSIIAILKELKPLVWIFLCQNVPEVVFLIYLLYTVIKEWGRGNSYTLEAAFITGSCISVAIKSVLFWALIHVYRGFGQGLRERMFSSYGRIDS", "length": 329, "header": "tr|A0A8V0ZCY0-1|A0A8V0ZCY0_CHICK Isoform 1 of DUF7789 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC419404 PE=4 SV=1 CANONICAL=A0A8V0ZCY0-1" }, "locus": { "chromosome": "21", "start_pos": 1997307, "end_pos": 1991163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048650.1", "url": "https://www.ensembl.org/id/ENSGALT00010048650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028741.1", "url": "https://www.ensembl.org/id/ENSGALP00010028741.1" } ] } }, { "isoform_ac": "A0A8V0ZJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0/entry#A0A8V0ZJH4-1", "sequence": { "sequence": "MEPAEESGPALPNLTPRHRELVPTPCGPIKPCSELSFPVKIYFCVTILSLLSVIGLTIETLVRQTEEDFTISLIQLVGVVMFRSIINFTVLPAEQKPKLLARFILILLVGSFDVICAIILIQSQSMMAFRVGGALESLQSQYFMLNLCFSMLTFDLQAQLCLCILLISLHEITLLHNIISATGVLWACLKVTVSIIAILKELKPLVWIFLCQNVPEVVFLIYLLYTVIKEWGRGNSYTLEAAFITGSCISVAIKSVLFWALIHVYRGFGQGLRERMFSSYGRIDS", "length": 285, "header": "tr|A0A8V0ZJH4-1|A0A8V0ZJH4_CHICK Computationally mapped isoform of DUF7789 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC419404 PE=4 SV=1 CANONICAL=A0A8V0ZCY0-1" }, "locus": { "chromosome": "21", "start_pos": 1998345, "end_pos": 1991163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048657.1", "url": "https://www.ensembl.org/id/ENSGALT00010048657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028748.1", "url": "https://www.ensembl.org/id/ENSGALP00010028748.1" } ] } }, { "isoform_ac": "E1BWP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0/entry#E1BWP1-1", "sequence": { "sequence": "MGCRLLVFCVYYVTRGILQENRQELIVFVLSILLVMFRSIINFTVLPAEQKPKLLARFILILLVGSFDVICAIILIQSQSMMAFRVGGALESLQSQYFMLNLCFSMLTFDLQAQLCLCILLISLHEITLLHNIISATGVLWACLKVTVSIIAILKELKPLVWIFLCQNVPEVVFLIYLLYTVIKEWGRGNSYTLEAAFITGSCISVAIKSVLFWALIHVYRGFGQGLRERMFSSYGRIDS", "length": 240, "header": "tr|E1BWP1-1|A0A8V0ZCY0_CHICK Computationally mapped isoform of DUF7789 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC419404 PE=4 SV=4 CANONICAL=A0A8V0ZCY0-1" }, "locus": { "chromosome": "21", "start_pos": 1995886, "end_pos": 1991163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048653.1", "url": "https://www.ensembl.org/id/ENSGALT00010048653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028744.1", "url": "https://www.ensembl.org/id/ENSGALP00010028744.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZCY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY0" }, { "id": "PF25044", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25044" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF7789", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 166, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZCY4-1", "uniprot_ac": "A0A8V0ZCY4", "uniprot_id": "A0A8V0ZCY4_CHICK", "mass": { "chemical_mass": 70104.0, "monoisotopic_mass": 70104.0 }, "refseq": { "ac": "XP_001232417", "name": "acid-sensing ion channel 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232417" }, "gene_names": [ { "name": "ASIC4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4" } ] }, { "name": "ASIC4", "type": "synonym", "evidence": [ { "id": "XP_001232417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232417" } ] } ], "protein_names": [ { "name": "Acid sensing ion channel subunit family member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4/entry#names_and_taxonomy" } ] }, { "name": "acid-sensing ion channel 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001232417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232417" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001232417.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASIC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4", "locus": { "chromosome": "7", "start_pos": 21708272, "end_pos": 21713823, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018361", "url": "https://www.ensembl.org/id/ENSGALG00010018361" } ] } } ], "crossref": [ { "id": "A0A8V0ZCY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZCY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "769191", "url": "https://www.ncbi.nlm.nih.gov/gene/769191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769191", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"##Evidence-Data-START## Transcript exon combination :: AJ720774.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000232.1. On Sep 23, 2021 this sequence version replaced NP_001026751.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026751", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026751" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08", "locus": { "chromosome": "6", "start_pos": 23041204, "end_pos": 23036454, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018374", "url": "https://www.ensembl.org/id/ENSGALG00010018374" } ] } } ], "crossref": [ { "id": "A0A8V0ZD08", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD08", "database": "AlphaFoldDB", "categories": [] }, { "id": "429879", "url": "https://www.ncbi.nlm.nih.gov/gene/429879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429879", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429879", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZD08", "url": "https://www.orthodb.org/?gene=A0A8V0ZD08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12761", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12761", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12761:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12761:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026751", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026751", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCVLIASTAAELLFYWADAAFLRRLRPPAATAAQGPALEDSLNTLFAPLIISCTALLEKLSDTYTCFRAERGQHLHVLHMFGDCLYIAVNGDGTESEDDLRRTLFVLRRLVEAHCGLVTLDAHLIRKELRPADSERRERIWSLLRGLLETYIRLREEDQSFAVEAVERLIHPQLCEQCIEFLEKQVVQHINASPERGGDEVGHAFLLVHTKLLAFYSSRNASSIRPADLLTLILLVQDLYPSQSVEEELGPQPAAGKSLPRGPKRSESIPVSNPSSHGATEKESDDQDTDDLSAPEVYYTPEPSPGRQSTGSESWSESLELVGDGDADTADVQMAEDLLQMLGPLLPEASNPRRIFLEANLRDGSYLLLPHTMHCFPLWPGISLVLLTKGPTSHVAVTLHQLLDGFLVLEKKLEEGQEVGAPRAHPFLAELRQRMDKFVKKLSGQDMQLQNAWVEFKNKIFSRSEAGSNLELLHALGTVKRQLCSVYRQLFLTPTSHSLSQGLRDRAQKLMREKLLDWRDFLLVKSRRNITMVSYLEDFPGLVHFIYVDRTAGQMMAPSLSVTEKSSSELGKGPLAEFVRSKVWSLIALARRYLQKGYTTLMLQDGDYCCSYFLWFENELGYKLEVLEMPVLSDDSAPIGMLAGDYYRKLLRYYSKNQQTEVVKCYELLTVHLGIIPSELVVQQACNLAQRLWEPSRIPLL", "length": 702, "header": "tr|A0A8V0ZD08-1|A0A8V0ZD08_CHICK Isoform 1 of HPS1, biosis of lysosomal organelles complex 3 subunit 1 OS=Gallus gallus OX=9031 GN=HPS1 PE=4 SV=1 CANONICAL=A0A8V0ZD08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08/entry#A0A8V0ZD08-1", "sequence": { "sequence": "MRCVLIASTAAELLFYWADAAFLRRLRPPAATAAQGPALEDSLNTLFAPLIISCTALLEKLSDTYTCFRAERGQHLHVLHMFGDCLYIAVNGDGTESEDDLRRTLFVLRRLVEAHCGLVTLDAHLIRKELRPADSERRERIWSLLRGLLETYIRLREEDQSFAVEAVERLIHPQLCEQCIEFLEKQVVQHINASPERGGDEVGHAFLLVHTKLLAFYSSRNASSIRPADLLTLILLVQDLYPSQSVEEELGPQPAAGKSLPRGPKRSESIPVSNPSSHGATEKESDDQDTDDLSAPEVYYTPEPSPGRQSTGSESWSESLELVGDGDADTADVQMAEDLLQMLGPLLPEASNPRRIFLEANLRDGSYLLLPHTMHCFPLWPGISLVLLTKGPTSHVAVTLHQLLDGFLVLEKKLEEGQEVGAPRAHPFLAELRQRMDKFVKKLSGQDMQLQNAWVEFKNKIFSRSEAGSNLELLHALGTVKRQLCSVYRQLFLTPTSHSLSQGLRDRAQKLMREKLLDWRDFLLVKSRRNITMVSYLEDFPGLVHFIYVDRTAGQMMAPSLSVTEKSSSELGKGPLAEFVRSKVWSLIALARRYLQKGYTTLMLQDGDYCCSYFLWFENELGYKLEVLEMPVLSDDSAPIGMLAGDYYRKLLRYYSKNQQTEVVKCYELLTVHLGIIPSELVVQQACNLAQRLWEPSRIPLL", "length": 702, "header": "tr|A0A8V0ZD08-1|A0A8V0ZD08_CHICK Isoform 1 of HPS1, biosis of lysosomal organelles complex 3 subunit 1 OS=Gallus gallus OX=9031 GN=HPS1 PE=4 SV=1 CANONICAL=A0A8V0ZD08-1" }, "locus": { "chromosome": "6", "start_pos": 23040888, "end_pos": 23036472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044369.1", "url": "https://www.ensembl.org/id/ENSGALT00010044369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026402.1", "url": "https://www.ensembl.org/id/ENSGALP00010026402.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429879", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429879", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "BLOC-3 complex", "id": "GO:0031085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "melanosome assembly", "id": "GO:1903232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" }, { "id": "PF19036", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 first Longin", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 153, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" }, { "id": "PF19037", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 second Longin", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 403, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD08" }, { "id": "PF19038", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 third Longin", "eco_id": "ECO_0000259", "start_pos": 542, "end_pos": 695, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 530, "end_pos": 532 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD10-1", "uniprot_ac": "A0A8V0ZD10", "uniprot_id": "A0A8V0ZD10_CHICK", "mass": { "chemical_mass": 25294.0, "monoisotopic_mass": 25294.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107056412", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10" } ] } ], "protein_names": [ { "name": "Membrane spanning 4-domains A4A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107056412", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZD10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD10", "database": "AlphaFoldDB", "categories": [] }, { "id": "107056412", "url": "https://www.ncbi.nlm.nih.gov/gene/107056412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107056412", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107056412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQGMGNF", "url": "https://omabrowser.org/oma/group/MQGMGNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD10", "url": "https://www.orthodb.org/?gene=A0A8V0ZD10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE23", "url": "https://www.orthodb.org/?gene=A0A8V0ZE23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIVPSTTRVDLAVVQAELPQPPSYSEVMATTVTESGGVRIITEVIPATDPRAAQLVSGSVQPTVSSFQISGFRRAQPKVLGTIHIVTGIIHLCFGVILTCAENNSALSLPVASGVFFWLGVLLLVSGSLLVESEKRENILLVKVCCVANAAVILSSLVAMLIHTVAITHNIPGCRSSASMPLLVRQEWCFSAETKALSNGFDSILVLFGLLEFCTAVAALAFGCTAIKQYSYTRMVL", "length": 238, "header": "tr|A0A8V0ZD10-1|A0A8V0ZD10_CHICK Isoform 1 of Membrane spanning 4-domains A4A OS=Gallus gallus OX=9031 GN=LOC107056412 PE=3 SV=1 CANONICAL=A0A8V0ZD10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10/entry#A0A8V0ZD10-1", "sequence": { "sequence": "MLIVPSTTRVDLAVVQAELPQPPSYSEVMATTVTESGGVRIITEVIPATDPRAAQLVSGSVQPTVSSFQISGFRRAQPKVLGTIHIVTGIIHLCFGVILTCAENNSALSLPVASGVFFWLGVLLLVSGSLLVESEKRENILLVKVCCVANAAVILSSLVAMLIHTVAITHNIPGCRSSASMPLLVRQEWCFSAETKALSNGFDSILVLFGLLEFCTAVAALAFGCTAIKQYSYTRMVL", "length": 238, "header": "tr|A0A8V0ZD10-1|A0A8V0ZD10_CHICK Isoform 1 of Membrane spanning 4-domains A4A OS=Gallus gallus OX=9031 GN=LOC107056412 PE=3 SV=1 CANONICAL=A0A8V0ZD10-1" }, "locus": { "chromosome": "5", "start_pos": 217767, "end_pos": 213458, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049228.1", "url": "https://www.ensembl.org/id/ENSGALT00010049228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029103.1", "url": "https://www.ensembl.org/id/ENSGALP00010029103.1" } ] } }, { "isoform_ac": "A0A8V0ZE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10/entry#A0A8V0ZE23-1", "sequence": { "sequence": "MQGMGTLRLGSRAVMYTAETLPKGKNRVMGTIQIMTGFMHIGFGIVLTTLTNVYSSIFITGEIPFLGGVSFIISGCLSIGAEKSPTECAVKGSQATNIISAIFALLGIVAFIIDLNFNGLYRSSDDYYSYLVLLAGNGISIVLLIFTILEFCIAVATANFWCRATRLSPNEAMLIVPSTTRVDLAVVQAELPQPPSYSELAAPEA", "length": 205, "header": "tr|A0A8V0ZE23-1|A0A8V0ZE23_CHICK Computationally mapped isoform of Membrane spanning 4-domains A4A OS=Gallus gallus OX=9031 GN=LOC107056412 PE=3 SV=1 CANONICAL=A0A8V0ZD10-1" }, "locus": { "chromosome": "5", "start_pos": 213635, "end_pos": 211570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049223.1", "url": "https://www.ensembl.org/id/ENSGALT00010049223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029100.1", "url": "https://www.ensembl.org/id/ENSGALP00010029100.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107056412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107056412", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSU4-1", "protein_name": "Membrane spanning 4-domains A15", "gene_name": "Ms4a15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWKRRGRGESAARTAAVASRLRPPGSLNTMSAPPASNGVFVVIPPSNASGLRPPPAILPTSMCQPPGIMQFEESPLGAQAPRATQPPDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLVRSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFSIPSPAVSPPPAYDNVAYMPKESSE", "length": 271 }, "evidence": [ { "id": "A0A8V0ZD10", "url": "https://omabrowser.org/oma/group/A0A8V0ZD10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UPL6-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 15", "gene_name": "Ms4a15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWERRGRGESAAGTAAVASRNASGLRPPPAILPTSMCQPPGIMQFEESQLGAQAPRATQPPDLRPMETFLTGEPKALGTVQILIGLIHLGFGSVLLMVRRGHLGMLFIEGGVPFWGGACFIISGSLSVAAERNHTSCLLKSSLGTNILSAMAAFAGTAILLMDFGVTNWDVGRGYLAVLTIFTILEFFIAVIATHFGCQATRAQTNASVIFLPNAFGTDFNIPSPAVSPPPAYDNVAYMPKESSE", "length": 245 }, "evidence": [ { "id": "A0A8V0ZD10", "url": "https://omabrowser.org/oma/group/A0A8V0ZD10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N5U1-1", "protein_name": "Membrane-spanning 4-domains subfamily A member 15", "gene_name": "MS4A15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV", "length": 240 }, "evidence": [ { "id": "A0A8V0ZD10", "url": "https://omabrowser.org/oma/group/A0A8V0ZD10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 64 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD11-1", "uniprot_ac": "A0A8V0ZD11", "uniprot_id": "A0A8V0ZD11_CHICK", "mass": { "chemical_mass": 72860.0, "monoisotopic_mass": 72860.0 }, "refseq": { "ac": "XP_015144324", "name": "cytoplasmic polyadenylation element-binding protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144324" }, "gene_names": [ { "name": "CPEB3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11" } ] }, { "name": "CPEB3", "type": "synonym", "evidence": [ { "id": "XP_015144324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144324" } ] } ], "protein_names": [ { "name": "Cytoplasmic polyadenylation element binding protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11/entry#names_and_taxonomy" } ] }, { "name": "cytoplasmic polyadenylation element-binding protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015144324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144324" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144324" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPEB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11", "locus": { "chromosome": "6", "start_pos": 21725624, "end_pos": 21647027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021518", "url": "https://www.ensembl.org/id/ENSGALG00010021518" } ] } } ], "crossref": [ { "id": "A0A8V0ZD11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD11", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423816", "url": "https://www.ncbi.nlm.nih.gov/gene/423816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD11", "url": "https://www.orthodb.org/?gene=A0A8V0ZD11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZIK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK50", "url": "https://www.orthodb.org/?gene=A0A8V0ZK50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK55", "url": "https://www.orthodb.org/?gene=A0A8V0ZK55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12566", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12566", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12566:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12566:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDDLLMDKSKAQPQQQRQQQQQQQDPNSAEAPSTPISSETPKPEDNSSVTSIGTSAPSQNSKEKMQMESPILPGLSFHQPQQEPAAGTSLSPSFGSTWSTGTTNTVDDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQHQQQQQQAQQQQQRRSPVSPNQAPFAQRNAAYSHQPIMTSKPSSSSASSSSSSSWNNHQNAAWSTPSNPWGGLQAGRDPRRAVGVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTPKSWMEDNAFRTDNGNNLLPFQDRNRPYDTFNLHSLENSLMDMIRTDHEPLKGRMGINFHHPGTDNIMALNTRSYGRRRGRSSLFPFEDGFLDDSHGDQSLSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS", "length": 657, "header": "tr|A0A8V0ZD11-1|A0A8V0ZD11_CHICK Isoform 1 of Cytoplasmic polyadenylation element binding protein 3 OS=Gallus gallus OX=9031 GN=CPEB3 PE=1 SV=1 CANONICAL=A0A8V0ZD11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11/entry#A0A8V0ZD11-1", "sequence": { "sequence": "MQDDLLMDKSKAQPQQQRQQQQQQQDPNSAEAPSTPISSETPKPEDNSSVTSIGTSAPSQNSKEKMQMESPILPGLSFHQPQQEPAAGTSLSPSFGSTWSTGTTNTVDDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQHQQQQQQAQQQQQRRSPVSPNQAPFAQRNAAYSHQPIMTSKPSSSSASSSSSSSWNNHQNAAWSTPSNPWGGLQAGRDPRRAVGVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTPKSWMEDNAFRTDNGNNLLPFQDRNRPYDTFNLHSLENSLMDMIRTDHEPLKGRMGINFHHPGTDNIMALNTRSYGRRRGRSSLFPFEDGFLDDSHGDQSLSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS", "length": 657, "header": "tr|A0A8V0ZD11-1|A0A8V0ZD11_CHICK Isoform 1 of Cytoplasmic polyadenylation element binding protein 3 OS=Gallus gallus OX=9031 GN=CPEB3 PE=1 SV=1 CANONICAL=A0A8V0ZD11-1" }, "locus": { "chromosome": "6", "start_pos": 21722681, "end_pos": 21647411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052182.1", "url": "https://www.ensembl.org/id/ENSGALT00010052182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031164.1", "url": "https://www.ensembl.org/id/ENSGALP00010031164.1" } ] } }, { "isoform_ac": "A0A8V0ZIK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD11/entry#A0A8V0ZIK6-1", "sequence": { "sequence": "MQDDLLMDKSKAQPQQQRQQQQQQQDPNSAEAPSTPISSETPKPEDNSSVTSIGTSAPSQNSKEKMQMESPILPGLSFHQPQQEPAAGTSLSPSFGSTWSTGTTNTVDDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQHQQQQQQAQQQQQRRSPVSPNQAPFAQRNAAYSHQPIMTSKPSSSSASSSSSSSWNNHQNAAWSTPSNPWGGLQAGRDPRRAVGVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTPKSWMEDNAFRTDNGNNLLPFQDRNRPYDTFNLHSLENSLMDMIRTDHEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDGFLDDSHGDQSLSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS", "length": 649, "header": "tr|A0A8V0ZIK6-1|A0A8V0ZIK6_CHICK Computationally mapped isoform of Cytoplasmic polyadenylation element binding protein 3 OS=Gallus gallus OX=9031 GN=CPEB3 PE=1 SV=1 CANONICAL=A0A8V0ZD11-1" }, "locus": { "chromosome": "6", "start_pos": 21722681, "end_pos": 21647411, "strand": "-", "evidence": [ { "database": "Ensembl 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"database": "Ensembl Peptide", "id": "ENSGALP00010031168.1", "url": "https://www.ensembl.org/id/ENSGALP00010031168.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZD13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEEKSWKGVSEAAFDRGCVAPPRTGDGERCCRLPLLLGSGLPGISLLSLVLSLLLYFRTSDLQSRVSHLEADRSTQLPAWLSADQMETAILGRVDQLLDEKLKFHLPRHREVRETHQQCNCPAGPPGATGRPGLPGDKGAMGIPGRPGLKGQPGEKGAPGEAGMSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGQKGEMGAAGPRGLPGPPGQKGEKGQCAEYSHRLLPLLNSVRLAPPPVIKRRTFQGEQGQAGIQGPPGPPGPPGPAGPAGPEGTPGQPGPIGPPGRAGEPGKPGRDGKGLPGPPGPKGDPGIQGYPGRKGEAGMSGLPGAHGLPGATGPKGEKGNTGIKGERGMPGLPGRHGMKGAPGTATAGMKGEPGTPGEKGEPGVPGRMGPPGLPGKRGQRGEKGRAGDPGLPGPKGEKGNGENALVGGKGEPGPPGLPGPPGPKGEAGDVGAAGSRGEKGERGAPGEQGPMGPRGPKGEPGKDEMMDYDGNISEALQEIRTLALMGPPGLPGVAGPPGPPGQKGEIGLPGPPGHDGEKGPRGKPGEMGPPGPHGLPGRDGPPGIKGEPGQIGVTGEKGDKGEPGQAGSPGLDGPTGEKGERGDQGMPGPPGLPGPIGLPGLTGEKGQPGERGDKGNPGESMSGPPGPQGPPGPPGLQGLPGPKGEAGIDGMKGEKGVQGEKGDRGPLGLPGTPGPIGVSGPAGPKGERGSKGDPGVVGPMGPAGLPGLQGLPGDKGIRGLRGFKGEKGEPGLPGLDGLDAPCPLGEDGLPVQGCWNKGQTPWLIAKK", "length": 800, "header": "tr|A0A8V0ZE31-1|A0A8V0ZE31_CHICK Isoform 1 of Collagen type XIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL13A1 PE=4 SV=1 CANONICAL=A0A8V0ZE31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE31/entry#A0A8V0ZD13-1", "sequence": { "sequence": "MLEEKSWKGVSEAAFDRGCVAPPRTGDGERCCRLPLLLGSGLPGISLLSLVLSLLLYFRTSDLQSRVSHLEADRSTQLPAWLSADQMETAILGRVDQLLDEKLKFHLPRHREVRETHQQCNCPAGPPGATGRPGLPGAPGEAGMSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGQKGEMGAAGPRGLPGPPGQKGEKGQCAEYSHREYLSTTLAALRSNQILTLKGEQGQAGIQGPPGPPGPPGPAGPAGPEGTPGQPGPIGPPGRAGEPGKPGRDGKGLPGPPGPKGDPGIQGYPGRKGAPGTATAGMKGEPGTPGEKGEPGVPGRMGPPGLPGKRGQRGEKGRAGDPGLPGPKGEKGNGENALVGGKGEPGPPGLPGPPGPKGEAGDVGAAGSRGEKGERGAPGEQGPMGPRGPKGEPGKDEMMDYDGNISEALQEIRTLALMGPPGLPGVAGPPGPPGQKGEIGLPGPPGHDGEKGPRGKPGEMGPPGPHGLPGRDGPPGIKGEPGQIGVTGEKGDKGEPGQAGSPGLDGPTGEKGERGDQGMPGPPGLPGPIGLPGLTGEKGQPGERGDKGNPGESMSGPPGPQGPPGPPGLQGLPGPKGEAGIDGMKGEKGVQGEKGDRGPLGLPGTPGPIGVSGPAGPKGERGSKGDPGVVGPMGPAGLPGLQGLPGDKGIRGERGKKGSRGSKGDKGDQGAPGLDAPCPLGEDGLPVQGCWNK", "length": 724, "header": "tr|A0A8V0ZD13-1|A0A8V0ZE31_CHICK Computationally mapped isoform of Collagen type XIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL13A1 PE=4 SV=1 CANONICAL=A0A8V0ZE31-1" }, "locus": { "chromosome": "6", "start_pos": 11802135, "end_pos": 11725307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049240.1", "url": "https://www.ensembl.org/id/ENSGALT00010049240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029109.1", "url": "https://www.ensembl.org/id/ENSGALP00010029109.1" } ] } }, { "isoform_ac": "A0A8V0ZE31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE31/entry#A0A8V0ZE31-1", "sequence": { "sequence": "MLEEKSWKGVSEAAFDRGCVAPPRTGDGERCCRLPLLLGSGLPGISLLSLVLSLLLYFRTSDLQSRVSHLEADRSTQLPAWLSADQMETAILGRVDQLLDEKLKFHLPRHREVRETHQQCNCPAGPPGATGRPGLPGDKGAMGIPGRPGLKGQPGEKGAPGEAGMSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGQKGEMGAAGPRGLPGPPGQKGEKGQCAEYSHRLLPLLNSVRLAPPPVIKRRTFQGEQGQAGIQGPPGPPGPPGPAGPAGPEGTPGQPGPIGPPGRAGEPGKPGRDGKGLPGPPGPKGDPGIQGYPGRKGEAGMSGLPGAHGLPGATGPKGEKGNTGIKGERGMPGLPGRHGMKGAPGTATAGMKGEPGTPGEKGEPGVPGRMGPPGLPGKRGQRGEKGRAGDPGLPGPKGEKGNGENALVGGKGEPGPPGLPGPPGPKGEAGDVGAAGSRGEKGERGAPGEQGPMGPRGPKGEPGKDEMMDYDGNISEALQEIRTLALMGPPGLPGVAGPPGPPGQKGEIGLPGPPGHDGEKGPRGKPGEMGPPGPHGLPGRDGPPGIKGEPGQIGVTGEKGDKGEPGQAGSPGLDGPTGEKGERGDQGMPGPPGLPGPIGLPGLTGEKGQPGERGDKGNPGESMSGPPGPQGPPGPPGLQGLPGPKGEAGIDGMKGEKGVQGEKGDRGPLGLPGTPGPIGVSGPAGPKGERGSKGDPGVVGPMGPAGLPGLQGLPGDKGIRGLRGFKGEKGEPGLPGLDGLDAPCPLGEDGLPVQGCWNKGQTPWLIAKK", "length": 800, "header": "tr|A0A8V0ZE31-1|A0A8V0ZE31_CHICK Isoform 1 of Collagen type XIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL13A1 PE=4 SV=1 CANONICAL=A0A8V0ZE31-1" }, "locus": { "chromosome": "6", "start_pos": 11804438, "end_pos": 11725307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049245.1", "url": "https://www.ensembl.org/id/ENSGALT00010049245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029111.1", "url": "https://www.ensembl.org/id/ENSGALP00010029111.1" } ] } }, { "isoform_ac": "A0A8V0ZEG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE31/entry#A0A8V0ZEG1-1", "sequence": { "sequence": "MLEEKSWKGVSEAAFDRGCVAPPRTGDGERCCRLPLLLGSGLPGISLLSLVLSLLLYFRTSDLQSRVSHLEADRSTQLPAWLSADQMETAILGRVDQLLDEKLKFHLPRHREVRETHQQCNCPAGPPGATGRPGLPGDKGAMGIPGRPGLKGQPGEKGAPGEAGMSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGQKGEMGAAGPRGLPGPPGQKGEKGQCAEYSHREYLSTTLAALRSNQILTLKGEQGQAGIQGPPGPPGPPGPAGPAGPEGTPGQPGPIGPPGRAGEPGKPGRDGKGLPGPPGPKGDPGIQGYPGRKGAPGTATAGMKGEPGTPGEKGEPGVPGRMGPPGLPGKRGQRGEKGRAGDPGLPGPKGEKGNGENALVGGKGEPGPPGLPGPPGPKGEAGDVGAAGSRGEKGERGAPGEQGPMGPRGPKGEPGKDEMMDYDGNISEALQEIRTLALMGPPGLPGVAGPPGPPGQKGEIGLPGPPGHDGEKGPRGKPGEMGPPGPHGLPGRDGPPGIKGEPGQIGVTGEKGDKGEPGQAGSPGLDGPTGEKGERGDQGMPGPPGLPGPIGLPGLTGEKGQPGERGDKGNPGESMSGPPGPQGPPGPPGLQGLPGPKGEAGIDGMKGEKGVQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVSGPAGPKGERGSKGDPGVVGPMGPAGLPGLQGLPGDKGIRGERGKKGSRGSKGDKGDQGAPGLDAPCPLGEDGLPVQGCWNK", "length": 757, "header": "tr|A0A8V0ZEG1-1|A0A8V0ZEG1_CHICK Computationally mapped isoform of Collagen type XIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL13A1 PE=4 SV=1 CANONICAL=A0A8V0ZE31-1" }, "locus": { "chromosome": "6", "start_pos": 11802135, "end_pos": 11725307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049244.1", "url": "https://www.ensembl.org/id/ENSGALT00010049244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029110.1", "url": "https://www.ensembl.org/id/ENSGALP00010029110.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 388, "start_aa": "Thr", "end_pos": 388, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr388", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 705, "start_aa": "Thr", "end_pos": 705, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr705", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 282, 388, 705 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 504, "end_pos": 506 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD21-1", "uniprot_ac": "A0A8V0ZD21", "uniprot_id": "A0A8V0ZD21_CHICK", "mass": { "chemical_mass": 51862.0, "monoisotopic_mass": 51862.0 }, "refseq": { "ac": "XP_004943704", "name": "CUGBP Elav-like family member 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943704" }, "gene_names": [ { "name": "CELF6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ] }, { "name": "CELF6", "type": "synonym", "evidence": [ { "id": "XP_004943704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943704" } ] } ], "protein_names": [ { "name": "CUGBP Elav-like family member 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943704" } ] }, { "name": "CUGBP Elav-like family member 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004943704.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943704" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CELF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21", "locus": { "chromosome": "10", "start_pos": 1635776, "end_pos": 1646053, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021523", "url": "https://www.ensembl.org/id/ENSGALG00010021523" } ] } } ], "crossref": [ { "id": "A0A8V0ZD21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12632", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12632", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427479", "url": "https://www.ncbi.nlm.nih.gov/gene/427479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427479", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GAYSHQM", "url": "https://omabrowser.org/oma/group/GAYSHQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD21", "url": "https://www.orthodb.org/?gene=A0A8V0ZD21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK60", "url": "https://www.orthodb.org/?gene=A0A8V0ZK60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR09", "url": "https://www.orthodb.org/?gene=A0A8V0ZR09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGSGVAAAEAGAGPAGAAFSTANSGRVNGLSHPPGAIAMKDHDAIKLFVGQIPRNLEESDLKPLFEEFGRIYELTVLKDRFTGMHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSEGRGEDRKLFVGMLGKQQSEDDVRRLFEPFGQIEECTILRGPDGASKGCAFVKYSSHAEAQAAISSLHGSQTMPGASSSLVVKFADTDKERTLRRMHQMAGQLGIFNPMTIQFGAYGAYTQAIMQQQAALMAAAQGTCLNPMAAIAAAQMQQMAAFNVSGLVAAPLTPSSGTSTPPGISTAPVPSIATPIGVNGFSPLPPQTNGQPTSETIYTNGIHPYPAQSPTVADPLQQAYAGMQHYAAAYPTAYAPISQAFPQQAPIIPQQQREGPEGCNLFIYHLPQEFGDAELTQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPTSAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 487, "header": "tr|A0A8V0ZD21-1|A0A8V0ZD21_CHICK Isoform 1 of CUGBP Elav-like family member 6 OS=Gallus gallus OX=9031 GN=CELF6 PE=3 SV=1 CANONICAL=A0A8V0ZD21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21/entry#A0A8V0ZD21-1", "sequence": { "sequence": "MAAAGSGVAAAEAGAGPAGAAFSTANSGRVNGLSHPPGAIAMKDHDAIKLFVGQIPRNLEESDLKPLFEEFGRIYELTVLKDRFTGMHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSEGRGEDRKLFVGMLGKQQSEDDVRRLFEPFGQIEECTILRGPDGASKGCAFVKYSSHAEAQAAISSLHGSQTMPGASSSLVVKFADTDKERTLRRMHQMAGQLGIFNPMTIQFGAYGAYTQAIMQQQAALMAAAQGTCLNPMAAIAAAQMQQMAAFNVSGLVAAPLTPSSGTSTPPGISTAPVPSIATPIGVNGFSPLPPQTNGQPTSETIYTNGIHPYPAQSPTVADPLQQAYAGMQHYAAAYPTAYAPISQAFPQQAPIIPQQQREGPEGCNLFIYHLPQEFGDAELTQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPTSAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 487, "header": "tr|A0A8V0ZD21-1|A0A8V0ZD21_CHICK Isoform 1 of CUGBP Elav-like family member 6 OS=Gallus gallus OX=9031 GN=CELF6 PE=3 SV=1 CANONICAL=A0A8V0ZD21-1" }, "locus": { "chromosome": "10", "start_pos": 1646050, "end_pos": 1636727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052205.1", "url": "https://www.ensembl.org/id/ENSGALT00010052205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031177.1", "url": "https://www.ensembl.org/id/ENSGALP00010031177.1" } ] } }, { "isoform_ac": "A0A8V0ZK60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21/entry#A0A8V0ZK60-1", "sequence": { "sequence": "MQLPQVPAPGPRPPVLWVPAGSKLLCIEMNRPIQVKPADSEGRGDRKLFVGMLGKQQSEDDVRRLFEPFGQIEECTILRGPDGASKGCAFVKYSSHAEAQAAISSLHGSQTMPGASSSLVVKFADTDKERTLRRMHQMAGQLGIFNPMTIQFGAYGAYTQAIMQQQAALMAAAQGTCLNPMAAIAAAQMQQMAAFNVSGLVAAPLTPSSGTSTPPGISTAPVPSIATPIGVNGFSPLPPQTNGQPTSETIYTNGIHPYPAQSPTVADPLQQAYAGMQHYAAAYPTAYAPISQAFPQQAPIIPQQQREGPEGCNLFIYHLPQEFGDAELTQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPTSAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 397, "header": "tr|A0A8V0ZK60-1|A0A8V0ZK60_CHICK Computationally mapped isoform of CUGBP Elav-like family member 6 OS=Gallus gallus OX=9031 GN=CELF6 PE=4 SV=1 CANONICAL=A0A8V0ZD21-1" }, "locus": { "chromosome": "10", "start_pos": 1642554, "end_pos": 1636727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052202.1", "url": "https://www.ensembl.org/id/ENSGALT00010052202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031174.1", "url": "https://www.ensembl.org/id/ENSGALP00010031174.1" } ] } }, { "isoform_ac": "A0A8V0ZR09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21/entry#A0A8V0ZR09-1", "sequence": { "sequence": "MAAAGSGVAAAEAGAGPAGAAFSTANSGRVNGLSHPPGAIAMKDHDAIKLFVGQIPRNLEESDLKPLFEEFGRIYELTVLKDRFTGMHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSEGRGEDRKLFVGMLGKQQSEDDVRRLFEPFGQIEECTILRGPDGASKGCAFVKYSSHAEAQAAISSLHGSQTMPGASSSLVVKFADTDKERTLRRMHQMAGQLGIFNPMTIQFGAYGAYTQAIMQQQAALMAAAQGTCLNPMAAIAAAQMQQMAAFNVSGLVAAPLTPSSGTSTPPGISTAPVPSIATPIGVNGFSPLPPQTNGQPTSETIYTNGIHPYPAAYPTAYAPISQAFPQQAPIIPQQQREGPEGCNLFIYHLPQEFGDAELTQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPTSAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 466, "header": "tr|A0A8V0ZR09-1|A0A8V0ZR09_CHICK Computationally mapped isoform of CUGBP Elav-like family member 6 OS=Gallus gallus OX=9031 GN=CELF6 PE=3 SV=1 CANONICAL=A0A8V0ZD21-1" }, "locus": { "chromosome": "10", "start_pos": 1646050, "end_pos": 1636727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052207.1", "url": "https://www.ensembl.org/id/ENSGALT00010052207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031179.1", "url": "https://www.ensembl.org/id/ENSGALP00010031179.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427479", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD21" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 129, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD29-1", "uniprot_ac": "A0A8V0ZD29", "uniprot_id": "A0A8V0ZD29_CHICK", "mass": { "chemical_mass": 90674.0, "monoisotopic_mass": 90674.0 }, "refseq": { "ac": "XP_004943030", "name": "inactive dipeptidyl peptidase 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943030" }, "gene_names": [ { "name": "DPP10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ] }, { "name": "DPP10", "type": "synonym", "evidence": [ { "id": "XP_004943030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943030" } ] } ], "protein_names": [ { "name": "Dipeptidyl peptidase like 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29/entry#names_and_taxonomy" } ] }, { "name": "inactive dipeptidyl peptidase 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943030" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943030.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943030" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29", "locus": { "chromosome": "7", "start_pos": 28806076, "end_pos": 29153305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021532", "url": "https://www.ensembl.org/id/ENSGALG00010021532" } ] } } ], "crossref": [ { "id": "A0A8V0ZD29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD29", "database": "AlphaFoldDB", "categories": [] }, { "id": "424280", "url": "https://www.ncbi.nlm.nih.gov/gene/424280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424280", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTSTEHH", "url": "https://omabrowser.org/oma/group/YTSTEHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD29", "url": "https://www.orthodb.org/?gene=A0A8V0ZD29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK77", "url": "https://www.orthodb.org/?gene=A0A8V0ZK77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKA5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAMKEQPAHPGGRGNPPPPQPDQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELANSSETRLSLEDLFRKEFIVHNPEAKWINDTAVVYKDRNGHVIELNVETNTTTLLLENTTFVTFKASRYSVSPDLRFVLLAYDVKQVFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDVKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLTINDSLVPNMVIPRFTGGLYPKGKQYPYPKAGQTNPTVKLSVVNLYGPAHTLELMPPDSFKSREYYITMVKWVSNTKAVVRWLNRHQNISILTVCETTTGACSRKYEMQSDLWVPKQNEEPIFSRDGTKFFMAVPVKQGGRGEFHHIAMFIVQAKSEQIMVRHLTSGNWEVIKILAYDESTQNIYFLSTEESPRGRQLHSVSTVGSLNRQCLSCNFLKDQCTYFSAKFSPMNRHFLLHCKGPGVPVVSVHSTTDSGKFYILENNAVLKEAVFKKKNSRTEIKMLHIEDYELPLQLSLPKDFTDRNQYALLLMIDEAPGSQLVTDKFHIDWDSVLVNSDNVIVARFDGRGSGFQGLKILQEVHRCLGSVEVKDQIAAVESLLKQPFIDPKRLSIFGKGYGGYIASMILKSSERLFKCGAVVAPITDMKLYASAFSERYLGIPSKEENTYQASSVLHNLHGLKEANLLIVHGTADTKVHFQHSAELIKHLIKAGVNYTMQIYPDEGHNIASEKSKYHLYSTILGFFSACLKEETPILPQEPEEDE", "length": 801, "header": "tr|A0A8V0ZD29-1|A0A8V0ZD29_CHICK Isoform 1 of Dipeptidyl peptidase like 10 OS=Gallus gallus OX=9031 GN=DPP10 PE=4 SV=1 CANONICAL=A0A8V0ZD29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29/entry#A0A8V0ZD29-1", "sequence": { "sequence": "MTAMKEQPAHPGGRGNPPPPQPDQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELANSSETRLSLEDLFRKEFIVHNPEAKWINDTAVVYKDRNGHVIELNVETNTTTLLLENTTFVTFKASRYSVSPDLRFVLLAYDVKQVFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDVKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLTINDSLVPNMVIPRFTGGLYPKGKQYPYPKAGQTNPTVKLSVVNLYGPAHTLELMPPDSFKSREYYITMVKWVSNTKAVVRWLNRHQNISILTVCETTTGACSRKYEMQSDLWVPKQNEEPIFSRDGTKFFMAVPVKQGGRGEFHHIAMFIVQAKSEQIMVRHLTSGNWEVIKILAYDESTQNIYFLSTEESPRGRQLHSVSTVGSLNRQCLSCNFLKDQCTYFSAKFSPMNRHFLLHCKGPGVPVVSVHSTTDSGKFYILENNAVLKEAVFKKKNSRTEIKMLHIEDYELPLQLSLPKDFTDRNQYALLLMIDEAPGSQLVTDKFHIDWDSVLVNSDNVIVARFDGRGSGFQGLKILQEVHRCLGSVEVKDQIAAVESLLKQPFIDPKRLSIFGKGYGGYIASMILKSSERLFKCGAVVAPITDMKLYASAFSERYLGIPSKEENTYQASSVLHNLHGLKEANLLIVHGTADTKVHFQHSAELIKHLIKAGVNYTMQIYPDEGHNIASEKSKYHLYSTILGFFSACLKEETPILPQEPEEDE", "length": 801, "header": "tr|A0A8V0ZD29-1|A0A8V0ZD29_CHICK Isoform 1 of Dipeptidyl peptidase like 10 OS=Gallus gallus OX=9031 GN=DPP10 PE=4 SV=1 CANONICAL=A0A8V0ZD29-1" }, "locus": { "chromosome": "7", "start_pos": 28989203, "end_pos": 28807954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052221.1", "url": "https://www.ensembl.org/id/ENSGALT00010052221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031193.1", "url": "https://www.ensembl.org/id/ENSGALP00010031193.1" } ] } }, { "isoform_ac": "A0A8V0ZIM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29/entry#A0A8V0ZIM2-1", "sequence": { "sequence": "MNKERAVIMFDFTAELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELANSSETRLSLEDLFRKEFIVHNPEAKWINDTAVVYKDRNGHVIELNVETNTTTLLLENTTFVTFKASRYSVSPDLRFVLLAYDVKQVFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDVKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLTINDSLVPNMVIPRFTGGLYPKGKQYPYPKAGQTNPTVKLSVVNLYGPAHTLELMPPDSFKSREYYITMVKWVSNTKAVVRWLNRHQNISILTVCETTTGACSRKYEMQSDLWVPKQNEEPIFSRDGTKFFMAVPVKQGGRGEFHHIAMFIVQAKSEQIMVRHLTSGNWEVIKILAYDESTQNIYFLSTEESPRGRQLHSVSTVGSLNRQCLSCNFLKDQCTYFSAKFSPMNRHFLLHCKGPGVPVVSVHSTTDSGKFYILENNAVLKEAVFKKKNSRTEIKMLHIEDYELPLQLSLPKDFTDRNQYALLLMIDEAPGSQLVTDKFHIDWDSVLVNSDNVIVARFDGRGSGFQGLKILQEVHRCLGSVEVKDQIAAVESLLKQPFIDPKRLSIFGKGYGGYIASMILKSSERLFKCGAVVAPITDMKLYASAFSERYLGIPSKEENTYQASSVLHNLHGLKEANLLIVHGTADTKVHFQHSAELIKHLIKAGVNYTMQIYPDEGHNIASEKSKYHLYSTILGFFSACLKEETPILPQEPEEDE", "length": 791, "header": "tr|A0A8V0ZIM2-1|A0A8V0ZIM2_CHICK Computationally mapped isoform of Dipeptidyl peptidase like 10 OS=Gallus gallus OX=9031 GN=DPP10 PE=4 SV=1 CANONICAL=A0A8V0ZD29-1" }, "locus": { "chromosome": "7", "start_pos": 29007806, "end_pos": 28807954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052223.1", "url": "https://www.ensembl.org/id/ENSGALT00010052223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031195.1", "url": "https://www.ensembl.org/id/ENSGALP00010031195.1" } ] } }, { "isoform_ac": "A0A8V0ZK77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29/entry#A0A8V0ZK77-1", "sequence": { "sequence": "MNQTATVSHHQVQCHSSRAAKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELANSSETRLSLEDLFRKEFIVHNPEAKWINDTAVVYKDRNGHVIELNVETNTTTLLLENTTFVTFKASRYSVSPDLRFVLLAYDVKQVFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDVKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLTINDSLVPNMVIPRFTGGLYPKGKQYPYPKAGQTNPTVKLSVVNLYGPAHTLELMPPDSFKSREYYITMVKWVSNTKAVVRWLNRHQNISILTVCETTTGACSRKYEMQSDLWVPKQNEEPIFSRDGTKFFMAVPVKQGGRGEFHHIAMFIVQAKSEQIMVRHLTSGNWEVIKILAYDESTQNIYFLSTEESPRGRQLHSVSTVGSLNRQCLSCNFLKDQCTYFSAKFSPMNRHFLLHCKGPGVPVVSVHSTTDSGKFYILENNAVLKEAVFKKKNSRTEIKMLHIEDYELPLQLSLPKDFTDRNQYALLLMIDEAPGSQLVTDKFHIDWDSVLVNSDNVIVARFDGRGSGFQGLKILQEVHRCLGSVEVKDQIAAVESLLKQPFIDPKRLSIFGKGYGGYIASMILKSSERLFKCGAVVAPITDMKLYASAFSERYLGIPSKEENTYQASSVLHNLHGLKEANLLIVHGTADTKVHFQHSAELIKHLIKAGVNYTMQIYPDEGHNIASEKSKYHLYSTILGFFSACLKEETPILPQEPEEDE", "length": 798, "header": "tr|A0A8V0ZK77-1|A0A8V0ZK77_CHICK Computationally mapped isoform of Dipeptidyl peptidase like 10 OS=Gallus gallus OX=9031 GN=DPP10 PE=4 SV=1 CANONICAL=A0A8V0ZD29-1" }, "locus": { "chromosome": "7", "start_pos": 29152991, "end_pos": 28807954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052225.1", "url": "https://www.ensembl.org/id/ENSGALT00010052225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031197.1", "url": "https://www.ensembl.org/id/ENSGALP00010031197.1" } ] } }, { "isoform_ac": "A0A8V0ZKA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29/entry#A0A8V0ZKA5-1", "sequence": { "sequence": "MCMAVQHHISADTAVVYKDRNGHVIELNVETNTTTLLLENTTFVTFKASRYSVSPDLRFVLLAYDVKQVFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDVKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLTINDSLVPNMVIPRFTGGLYPKGKQYPYPKAGQTNPTVKLSVVNLYGPAHTLELMPPDSFKSREYYITMVKWVSNTKAVVRWLNRHQNISILTVCETTTGACSRKYEMQSDLWVPKQNEEPIFSRDGTKFFMAVPVKQGGRGEFHHIAMFIVQAKSEQIMVRHLTSGNWEVIKILAYDESTQNIYFLSTEESPRGRQLHSVSTVGSLNRQCLSCNFLKDQCTYFSAKFSPMNRHFLLHCKGPGVPVVSVHSTTDSGKFYILENNAVLKEAVFKKKNSRTEIKMLHIEDYELPLQLSLPKDFTDRNQYALLLMIDEAPGSQLVTDKFHIDWDSVLVNSDNVIVARFDGRGSGFQGLKILQEVHRCLGSVEVKDQIAAVESLLKQPFIDPKRLSIFGKGYGGYIASMILKSSERLFKCGAVVAPITDMKLYASAFSERYLGIPSKEENTYQASSVLHNLHGLKEANLLIVHGTADTKVHFQHSAELIKHLIKAGVNYTMQIYPDEGHNIASEKSKYHLYSTILGFFSACLKEETPILPQEPEEDE", "length": 718, "header": "tr|A0A8V0ZKA5-1|A0A8V0ZKA5_CHICK Computationally mapped isoform of Dipeptidyl peptidase like 10 OS=Gallus gallus OX=9031 GN=DPP10 PE=4 SV=1 CANONICAL=A0A8V0ZD29-1" }, "locus": { "chromosome": "7", "start_pos": 28939084, "end_pos": 28807954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052218.1", "url": "https://www.ensembl.org/id/ENSGALT00010052218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031190.1", "url": "https://www.ensembl.org/id/ENSGALP00010031190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424280", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6NXK7-1", "protein_name": "Inactive dipeptidyl peptidase 10", "gene_name": "Dpp10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQEQQPTPGARATQSQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEELLGKGFGLHNPEPRWINDTVVVYKTNNGHVMKLNTESNASTLLLDNSTFVTFKASRHSLSPDLKYVLLAYDVKQIFHYSFTASYLIYNIHTGEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMIIPRFTGALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTLELMPPDIFKSREYYITMVKWVSNTRTVVRWLNRPQNISILTLCESTTGACSRKYEMTSDTWLSKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILAYDETTQKIYFLSTESSPQGRQLYSASTEGLLNRDCISCNFMKEDCTYFDASFSPMNQHFLLFCEGPKVPVVSLHITDNPSRYFLLENNSVMKETIQKKKLAKRETRILHIDDYELPLQLSFPKDFMEKNQYALLLIMDEEPGGQMVTDKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRIGSVEAKDQVAAVKYLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKFFKCGAVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKEENLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDCLKEEVSVLPQEPEEDE", "length": 797 }, "evidence": [ { "id": "A0A8V0ZD29", "url": "https://omabrowser.org/oma/group/A0A8V0ZD29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q629-1", "protein_name": "Inactive dipeptidyl peptidase 10", "gene_name": "Dpp10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQTASVSHHIKCQPSKTIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEELLGKGFGLHNPEARWINDTDVVYKTDNGHVMKLNAETNATTLLLDNSTFVTFKASRHSLSPDLKYVLLAYDVKQIFHYSFTASYLIYNIHTGEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIVFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTLELMPPDIFKSREYYITMVKWVSNTRTVVRWLNRPQNISILTVCESTTGACSRKYEMTSDTWISKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILAYDETTQKIYFLSTEFSPRGRQLYSASTEGLLSRDCISCNFRKEDCTYFDASFSPMNQHFLLFCEGPKVPMVSLHSTDNPSNYYILERNSMMKETIQKKKLAKREIRILHIDDYELPLQLSFPKDFLEKNQYALLLIIDEEPGGQMVTEKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRTGSVEAKDQIAAIKYLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKFFKCGTVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKEENLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDCLKEEVSVLPQEPEEDE", "length": 796 }, "evidence": [ { "id": "A0A8V0ZD29", "url": "https://omabrowser.org/oma/group/A0A8V0ZD29/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N608-1", "protein_name": "Inactive dipeptidyl peptidase 10", "gene_name": "DPP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNQTASVSHHIKCQPSKTIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHVAMFLIQSKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILKFFSDCLKEEISVLPQEPEEDE", "length": 796 }, "evidence": [ { "id": "A0A8V0ZD29", "url": "https://omabrowser.org/oma/group/A0A8V0ZD29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X2J9P4-1", "protein_name": "Venom dipeptidyl peptidase 4", "gene_name": "Dpp10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPEQDNYDDELVSSNPNQRNWRGILIALLVIIIVLALIVTSVVLLTPPDEGPRVKGQRIKLQDIVDGLFVPQHSNGSWIDGEEFLYQDHLGRICLLNAANRSERVLMSNVTFKTLSPFTFTISADKRYLLLAQNVVKLFRHSYLAQYTLYDIQTSESIKLRHSPHQDEWPYLHYARFTPAGNALVWVQSYDIYYREEVRSASVHRITHDAVPGVVYNGIPDWLYEEEILHANNAIWMSDNGQLMLYATFNDTHVQEQHFAWYGTTGPSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADLKDPLKVHITDLHPPQIIANEDHYFSSASWVSHSKIAVVWLNRPQNISVVSVCKAPLFQCIETHRVSGDGRGWVDTVAVPLFAANASIYVAISPLRDGLFGYFRHIVHVDIDKNRVLPLTHGPYEVNRLLHWDQLDNWIYFLGTPERLPSQQHLYRVSALPARQGQALRSPDCLTCPAVSQWSEGYDEGHTKSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPISRQAKYVLIDCLGPVVPTSILYGLKSAAADSAKTKRHSTQQEEPPTEGGDEKPGEEPKSQFLELLVIVQNNTRLKEKMAKTAMPQIKTFPVMISGGYHAQVRLYLPPVLREDEITRYPTILHVYSGPGSQLVTDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALALAGQQSIFQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKYVDNLRDRQFLLVHGTADDNVHVQQSMVLARSLTSKGVLYKQQIYPDEGHSLSGVKRHLYRSMTAFFEDCFKKLIDQQQQNQTDSMDFLDFHSFYGR", "length": 940 }, "evidence": [ { "id": "A0A8V0ZD29", "url": "https://omabrowser.org/oma/group/A0A8V0ZD29/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD69-1", "uniprot_ac": "A0A8V0ZD69", "uniprot_id": "A0A8V0ZD69_CHICK", "mass": { "chemical_mass": 49618.0, "monoisotopic_mass": 49618.0 }, "refseq": { "ac": "NP_001034352", "name": "ribosomal L1 domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034352" }, "gene_names": [ { "name": "RSL1D1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ] }, { "name": "RSL1D1", "type": "synonym", "evidence": [ { "id": "NP_001034352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034352" } ] } ], "protein_names": [ { "name": "Ribosomal L1 domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69/entry#names_and_taxonomy" } ] }, { "name": "ribosomal L1 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001034352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034352" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000816.1, HAEL01001040.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001034352.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001034352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034352" } ] }, { "annotation": "Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69#function" }, { "database": "UniProtKB", "id": "ARBA00054167", "url": "https://www.uniprot.org/uniprotkb/ARBA00054167#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RSL1D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69", "locus": { "chromosome": "14", "start_pos": 112510, "end_pos": 119552, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020184", "url": "https://www.ensembl.org/id/ENSGALG00010020184" } ] } } ], "crossref": [ { "id": "A0A8V0ZD69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD69", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416416", "url": "https://www.ncbi.nlm.nih.gov/gene/416416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416416", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZD69", "url": "https://www.orthodb.org/?gene=A0A8V0ZD69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJP0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001034352", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKGQQKLGRGQVRKAVEALLSFARSKAKGDALLLNENESVHLLVTVWKIPRVAQVIKIPLPHGIRAETAEVCLFTKDEPDLSAEQTESLYRKLLTQNGITSVSQVISYKTLKKEYKPFEAKRRLLNRFDLFLSDDRIRRLLPSHLGKHFYEKKKAPLSVNLKAKNLAKELQKHIQGTVLPVTNKGCCYTTRIGHTGMKADEILDNIIAAAEVIAKKLPKNWKNVKVLHLKTLKSVALPIFTARISNLDELDKEPNVNKKQGEKEKKKKPKKAAKKVNSSQNTTTAKSKAAAATHELVIKEEVVQEPEERADDEEIPQLVPMQVTSLAELKKEEPSQSPEKGDNLGNKTKATLGKRKKQFLAPETSKQKVMEEQADLQMSPKQKKAMQLSMAKEEIKELEKTLRKPEAKSFATHKAGKLVQSSKKSSKTPKQAAKKACRPQSS", "length": 443, "header": "tr|A0A8V0ZD69-1|A0A8V0ZD69_CHICK Isoform 1 of Ribosomal L1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RSL1D1 PE=1 SV=1 CANONICAL=A0A8V0ZD69-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69/entry#A0A8V0ZD69-1", "sequence": { "sequence": "MAKGQQKLGRGQVRKAVEALLSFARSKAKGDALLLNENESVHLLVTVWKIPRVAQVIKIPLPHGIRAETAEVCLFTKDEPDLSAEQTESLYRKLLTQNGITSVSQVISYKTLKKEYKPFEAKRRLLNRFDLFLSDDRIRRLLPSHLGKHFYEKKKAPLSVNLKAKNLAKELQKHIQGTVLPVTNKGCCYTTRIGHTGMKADEILDNIIAAAEVIAKKLPKNWKNVKVLHLKTLKSVALPIFTARISNLDELDKEPNVNKKQGEKEKKKKPKKAAKKVNSSQNTTTAKSKAAAATHELVIKEEVVQEPEERADDEEIPQLVPMQVTSLAELKKEEPSQSPEKGDNLGNKTKATLGKRKKQFLAPETSKQKVMEEQADLQMSPKQKKAMQLSMAKEEIKELEKTLRKPEAKSFATHKAGKLVQSSKKSSKTPKQAAKKACRPQSS", "length": 443, "header": "tr|A0A8V0ZD69-1|A0A8V0ZD69_CHICK Isoform 1 of Ribosomal L1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RSL1D1 PE=1 SV=1 CANONICAL=A0A8V0ZD69-1" }, "locus": { "chromosome": "14", "start_pos": 119516, "end_pos": 114354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048757.1", "url": "https://www.ensembl.org/id/ENSGALT00010048757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028821.1", "url": "https://www.ensembl.org/id/ENSGALP00010028821.1" } ] } }, { "isoform_ac": "A0A8V0ZJP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69/entry#A0A8V0ZJP0-1", "sequence": { "sequence": "MRGGGLGSAFVFRSSPLPYSGCYCRCRPLPHGIRAETAEVCLFTKDEPDLSAEQTESLYRKLLTQNGITSVSQVISYKTLKKEYKPFEAKRRLLNRFDLFLSDDRIRRLLPSHLGKHFYEKKKAPLSVNLKAKNLAKELQKHIQGTVLPVTNKGCCYTTRIGHTGMKADEILDNIIAAAEVIAKKLPKNWKNVKVLHLKTLKSVALPIFTARISNLDELDKEPNVNKKQGEKEKKKKPKKAAKKVNSSQNTTTAKSKAAAATHELVIKEEVVQEPEERADDEEIPQLVPMQVTSLAELKKEEPSQSPEKGDNLGNKTKATLGKRKKQFLAPETSKQKVMEEQADLQMSPKQKKAMQLSMAKEEIKELEKTLRKPEAKSFATHKAGKLVQSSKKSSKTPKQAAKKACRPQSS", "length": 411, "header": "tr|A0A8V0ZJP0-1|A0A8V0ZJP0_CHICK Computationally mapped isoform of Ribosomal L1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RSL1D1 PE=1 SV=1 CANONICAL=A0A8V0ZD69-1" }, "locus": { "chromosome": "14", "start_pos": 119477, "end_pos": 114354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048753.1", "url": "https://www.ensembl.org/id/ENSGALT00010048753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028818.1", "url": "https://www.ensembl.org/id/ENSGALP00010028818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416416", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" }, { "name": "regulation of cellular senescence", "id": "GO:2000772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000772", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZD77-1", "uniprot_ac": "A0A8V0ZD77", "uniprot_id": "A0A8V0ZD77_CHICK", "mass": { "chemical_mass": 33985.0, "monoisotopic_mass": 33985.0 }, "refseq": { "ac": "XP_040509249", "name": "sorting nexin-11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509249" }, "gene_names": [ { "name": "SNX11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ] }, { "name": "SNX11", "type": "synonym", "evidence": [ { "id": "XP_040509249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509249" } ] } ], "protein_names": [ { "name": "Sorting nexin 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040509249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509249" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77", "locus": { "chromosome": "27", "start_pos": 3662538, "end_pos": 3669731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021554", "url": "https://www.ensembl.org/id/ENSGALG00010021554" } ] } } ], "crossref": [ { "id": "A0A8V0ZD77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZD77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017553", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017553", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429353", "url": "https://www.ncbi.nlm.nih.gov/gene/429353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429353", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRISCAR", "url": "https://omabrowser.org/oma/group/DRISCAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD77", "url": "https://www.orthodb.org/?gene=A0A8V0ZD77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD88", "url": "https://www.orthodb.org/?gene=A0A8V0ZD88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "H9L0R3", "url": "https://www.orthodb.org/?gene=H9L0R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46209", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46209", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46209:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46209:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509249", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L0R3", "url": "https://www.uniprot.org/uniprotkb/H9L0R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L0R3-1", "url": "https://www.uniprot.org/uniprotkb/H9L0R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELQGKEMLHVPVLVMEQPPASPSRSLMGCVAHGECGRLMLLCSLPWGLLDLDASSSFYGGLLDRISCARTGGWRGAAGCFLLGSGSRMLESREEELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 308, "header": "tr|A0A8V0ZD77-1|A0A8V0ZD77_CHICK Isoform 1 of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=1 CANONICAL=A0A8V0ZD77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#A0A8V0ZD77-1", "sequence": { "sequence": "MELQGKEMLHVPVLVMEQPPASPSRSLMGCVAHGECGRLMLLCSLPWGLLDLDASSSFYGGLLDRISCARTGGWRGAAGCFLLGSGSRMLESREEELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 308, "header": "tr|A0A8V0ZD77-1|A0A8V0ZD77_CHICK Isoform 1 of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=1 CANONICAL=A0A8V0ZD77-1" }, "locus": { "chromosome": "27", "start_pos": 3666310, "end_pos": 3663516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052287.1", "url": "https://www.ensembl.org/id/ENSGALT00010052287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031238.1", "url": "https://www.ensembl.org/id/ENSGALP00010031238.1" } ] } }, { "isoform_ac": "A0A8V0ZD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#A0A8V0ZD88-1", "sequence": { "sequence": "MASSCCWVPGTASSQREERGTDCPWRCFLLGSGSRMLESREEELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 255, "header": "tr|A0A8V0ZD88-1|A0A8V0ZD88_CHICK Computationally mapped isoform of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=1 CANONICAL=A0A8V0ZD77-1" }, "locus": { "chromosome": "27", "start_pos": 3669532, "end_pos": 3663516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052305.1", "url": "https://www.ensembl.org/id/ENSGALT00010052305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031248.1", "url": "https://www.ensembl.org/id/ENSGALP00010031248.1" } ] } }, { "isoform_ac": "A0A8V0ZKC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#A0A8V0ZKC5-1", "sequence": { "sequence": "MLESREELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 219, "header": "tr|A0A8V0ZKC5-1|A0A8V0ZKC5_CHICK Computationally mapped isoform of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=1 CANONICAL=A0A8V0ZD77-1" }, "locus": { "chromosome": "27", "start_pos": 3665941, "end_pos": 3663516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052302.1", "url": "https://www.ensembl.org/id/ENSGALT00010052302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031247.1", "url": "https://www.ensembl.org/id/ENSGALP00010031247.1" } ] } }, { "isoform_ac": "A0A8V0ZKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#A0A8V0ZKG0-1", "sequence": { "sequence": "MGCFLLGSGSRMLESREEELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 231, "header": "tr|A0A8V0ZKG0-1|A0A8V0ZKG0_CHICK Computationally mapped isoform of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=1 CANONICAL=A0A8V0ZD77-1" }, "locus": { "chromosome": "27", "start_pos": 3666936, "end_pos": 3663516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052292.1", "url": "https://www.ensembl.org/id/ENSGALT00010052292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031241.1", "url": "https://www.ensembl.org/id/ENSGALP00010031241.1" } ] } }, { "isoform_ac": "H9L0R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77/entry#H9L0R3-1", "sequence": { "sequence": "MLESREEELTTVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRRQLQKNAGLVPVPELPGKSTFFVGSTDEFIEKRRQGLQQFLEKVVQNVVLLSDSRLHLFLQSQLSVPEIEACVQGQGSQTVTEAILHYAMSNCGWVQEEESRPTLLPGGGVHGSCASLGATQGLSCLETLPHWSDFGMDDAHSDSPDEPAEPLGGQQEMH", "length": 220, "header": "tr|H9L0R3-1|A0A8V0ZD77_CHICK Computationally mapped isoform of Sorting nexin 11 OS=Gallus gallus OX=9031 GN=SNX11 PE=3 SV=3 CANONICAL=A0A8V0ZD77-1" }, "locus": { "chromosome": "27", "start_pos": 3665941, "end_pos": 3663516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052296.1", "url": "https://www.ensembl.org/id/ENSGALT00010052296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031245.1", "url": "https://www.ensembl.org/id/ENSGALP00010031245.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429353", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD77" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 214, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { 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"MEPRSARQGPSRARRPRASPRRSAQQGSATRSPRSAVQPSSATESRTVLQRAGDVATTSSSDSEEELIPLKELLACSGRSSPAEHGEVACPQPDPLANSLDALLLEKREQCPASAAQASLTQADVDSGSPQESSDEDTQLLEEQRAFLSHFNVKLLTFPTTHPGEPIFHACPLPPPTLDTHRLQPRSVLEQNFLCASPAGQVAFVHDGYLNLLYNTTSACPLPVLRWLFQLTSIWPDRTNAFRTLWEMWMRSDDEPWCPTLQDIGQAFAYMGADLEALRCRRLLPPELCPMDTRLDPSLSQEQGNLSAADTLALVTQLGDICKLLTVCVVACPCRYPDRARRELVTLLCFLSLDHALCCQPLPDLWHLLHCLLEGIVAWKEQGAPQAPEPLCHGPTAGEGTVHRAVPWGAGRGGCSPPGAHPAVPECPLTQRSHSCRRWSSSWRNPGRTACSSPLTPMQWTSSRRWVLPFRGCHPQEVPPTPLVTPLSPQSCYLSRSLLYLADVVVGAERPQDEQRVCANPGGCRGVPTHPLPPSLCPRRDTYSGSAPSWSSTLGRGCVRTWGSSTAPS", "length": 569, "header": "tr|A0A8V0ZE96-1|A0A8V0ZE96_CHICK Isoform 1 of Family with sequence similarity 178 member B OS=Gallus gallus OX=9031 GN=FAM178B PE=3 SV=1 CANONICAL=A0A8V0ZE96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE96/entry#A0A8V0ZD91-1", "sequence": { "sequence": "MEPRSARQGPSRARRPRASPRRSAQQGSATRSPRSAVQPSSATESRTVLQRAGDVATTSSSDSEEELIPLKELLACSGRSSPAEHGEVACPQPDPLANSLDALLLEKREQCPASAAQASLTQADVDSGSPQESSDEDTQLLEEQRAFLSHFNVKLLTFPTTHPGEPIFHACPLPPPTLDTHRLQPRSVLEQNFLCASPAGQVAFVHDGYLNLLYNTTSACPLPVLRWLFQLTSIWPDRTNAFRTLWEMWMRSDDEPWCPTLQDIGQAFAYMGADLEALRCRRLLPPELCPMDTRLDPSLSQEQGNLSAADTLALVTQLGDICKLLTVCVVACPCRYPDRARRELVTLLCFLSLDHALCCQPLPDLWHLLHCLLEGIVAWKEQLPALCLSLCQLSQHHHNLLAVARLLPDITDRERELRRRLSLCAMAQLLGRAPCTVLSLGAQEELPALEQLLAQSWPDSLQLPTHPDAMDLEQESCYLSRSLLYLADVVVGAERPQDEQRGHLQRLCTQLEQYFGSGLREDMGQFYRSQLKNLATVLYVKWHELLE", "length": 547, "header": "tr|A0A8V0ZD91-1|A0A8V0ZE96_CHICK Computationally mapped isoform of Family with sequence similarity 178 member B OS=Gallus gallus OX=9031 GN=FAM178B PE=3 SV=1 CANONICAL=A0A8V0ZE96-1" }, "locus": { "chromosome": "22", "start_pos": 2965549, "end_pos": 2961882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049376.1", "url": "https://www.ensembl.org/id/ENSGALT00010049376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029186.1", "url": "https://www.ensembl.org/id/ENSGALP00010029186.1" } ] } }, { "isoform_ac": "A0A8V0ZE96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE96/entry#A0A8V0ZE96-1", "sequence": { "sequence": "MEPRSARQGPSRARRPRASPRRSAQQGSATRSPRSAVQPSSATESRTVLQRAGDVATTSSSDSEEELIPLKELLACSGRSSPAEHGEVACPQPDPLANSLDALLLEKREQCPASAAQASLTQADVDSGSPQESSDEDTQLLEEQRAFLSHFNVKLLTFPTTHPGEPIFHACPLPPPTLDTHRLQPRSVLEQNFLCASPAGQVAFVHDGYLNLLYNTTSACPLPVLRWLFQLTSIWPDRTNAFRTLWEMWMRSDDEPWCPTLQDIGQAFAYMGADLEALRCRRLLPPELCPMDTRLDPSLSQEQGNLSAADTLALVTQLGDICKLLTVCVVACPCRYPDRARRELVTLLCFLSLDHALCCQPLPDLWHLLHCLLEGIVAWKEQGAPQAPEPLCHGPTAGEGTVHRAVPWGAGRGGCSPPGAHPAVPECPLTQRSHSCRRWSSSWRNPGRTACSSPLTPMQWTSSRRWVLPFRGCHPQEVPPTPLVTPLSPQSCYLSRSLLYLADVVVGAERPQDEQRVCANPGGCRGVPTHPLPPSLCPRRDTYSGSAPSWSSTLGRGCVRTWGSSTAPS", "length": 569, "header": "tr|A0A8V0ZE96-1|A0A8V0ZE96_CHICK Isoform 1 of Family with sequence similarity 178 member B OS=Gallus gallus OX=9031 GN=FAM178B PE=3 SV=1 CANONICAL=A0A8V0ZE96-1" }, "locus": { "chromosome": "22", "start_pos": 2965499, "end_pos": 2961882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049358.1", "url": "https://www.ensembl.org/id/ENSGALT00010049358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029178.1", "url": "https://www.ensembl.org/id/ENSGALP00010029178.1" } ] } }, { "isoform_ac": "A0A8V0ZEA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE96/entry#A0A8V0ZEA1-1", "sequence": { "sequence": "MEPRSARQGPSRARRPRASPRRSAQQGSATRSPRSAVQPSSATESRTVLQRAGDVATTSSSDSEEELIPLKELLACSGRSSPAEHGEVACPQPDPLANSLDALLLEKREQCPASAAQASLTQADVDSGSPQESSDEDTQLLEEQRAFLSHFNVKLLTFPTTHPGEPIFHACPLPPPTLDTHRLQPRSVLEQNFLCASPAGQVAFVHDGYLNLLYNTTSACPLPVLRWLFQLTSIWPDRTNAFRTLWEMWMRSDDEPWCPTLQDIGQAFAYMGADLEALRCRRLLPPELCPMDTRLDPSLSQEQGNLSAADTLALVTQLGDICKLLTVCVVACPCRYPDRARRELVTLLCFLSLDHALCCQPLPDLWHLLHCLLEGIVAWKEQLPALCLSLCQLSQHHHNLLAVARLLPDITDRERELRRRLSLCAMAQLLGRAPCTVLSLGAQEELPALEQLLAQSWPDSLQLPTHPDAMDLEQEGHLQRLCTQLEQYFGSGLREDMGQFYRSQLKNLATVLYVKWHELLE", "length": 521, "header": "tr|A0A8V0ZEA1-1|A0A8V0ZEA1_CHICK Computationally mapped isoform of Family with sequence similarity 178 member B OS=Gallus gallus OX=9031 GN=FAM178B PE=3 SV=1 CANONICAL=A0A8V0ZE96-1" }, "locus": { "chromosome": "22", "start_pos": 2965549, "end_pos": 2961882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049368.1", "url": "https://www.ensembl.org/id/ENSGALT00010049368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029183.1", "url": "https://www.ensembl.org/id/ENSGALP00010029183.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 396, "start_aa": "Thr", "end_pos": 396, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr396", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": 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"start_pos": 215, "end_pos": 217 }, { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "name": "CNTN4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ] }, { "name": "CNTN4", "type": "synonym", "evidence": [ { "id": "XP_046755989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755989" } ] } ], "protein_names": [ { "name": "Contactin 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2/entry#names_and_taxonomy" } ] }, { "name": "contactin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046755989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755989" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046755989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755989" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNTN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2", "locus": { "chromosome": "12", "start_pos": 18269853, "end_pos": 18011810, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020436", "url": "https://www.ensembl.org/id/ENSGALG00010020436" } ] } } ], "crossref": [ { "id": "A0A8V0ZEQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEQ2", "database": 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Classification" ] }, { "id": "RIQGYEX", "url": "https://omabrowser.org/oma/group/RIQGYEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEC2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046755989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046755989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLLWELLVLQSFMVCLADDNMLHGPVFLQEPSSVIFPLDSEEKKVKLNCEVKGNPRPTIGWKLNGTNIDIGMDYRYSMVEGNLLINNPNRTQDTGTYQCVATNPFGRIISREAKLQFAYLENFKTRVRSTVSVRQGQGMVLLCGPPPHSGELTYAWIFNEYPSFVHQDNRRFVSQETGNLYIAKVEASDVGNYTCVVTNTVTNSRVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPSAKGTAVKLECFALGNPVPTISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDAGMYQCVAENRHGTIFASAELSVIAVGPDFSKTLLKKLTLVKVGGEVIIECKPKASPRPTYSWKKGKDILRENERITVLDDGSLRIVNVTKSDTGSYTCVATNHFGTASSTGSLVVKDPTRVMVSPFSMDVTVGESIVLPCQVSHDHSLDIVFTWSFNGHLIDFEKDGDHFERVGGQDSAGDLMIRSIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEDVTIDEITDTTAQLSWRPGADNHSPITMYVVQARTPFSVGWQAVSTVPEVIDGKTFTATVVGLNPWVEYEFRVVAANLIGIGEPSRPSENRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGGGFGYVVAFRPFGTISWMQTVVASPDASRYVFRNESLPPFSPYEVKVGVYNNKGEGSFSPVTVVYSAEEEPTKAPITVLARSLSATDIEISWAPPRENQHKGRIQGYEVRCWRHDEKEENARKIRTVGNQTSAKVTNLQGNALYHLAVKAYNTAGTGPSSAMVNVTTKKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVRGYKVLYKWNRQSSASVIETNRTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGGSSSTSNACTLSAISTIMISLTARSSL", "length": 1029, "header": "tr|A0A8V0ZEQ2-1|A0A8V0ZEQ2_CHICK Isoform 1 of Contactin 4 OS=Gallus gallus OX=9031 GN=CNTN4 PE=3 SV=1 CANONICAL=A0A8V0ZEQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2/entry#A0A8V0ZDA6-1", "sequence": { "sequence": "MRLLWELLVLQSFMVCLADDNMLHGPVFLQEPSSVIFPLDSEEKKVKLNCEVKGNPRPTIGWKLNGTNIDIGMDYRYSMVEGNLLINNPNRTQDTGTYQCVATNPFGRIISREAKLQFAYLENFKTRVRSTVSVRQGQGMVLLCGPPPHSGELTYAWIFNEYPSFVHQDNRRFVSQETGNLYIAKVEASDVGNYTCVVTNTVTNSRVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPSAKGTAVKLECFALGNPVPTISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDAGMYQCVAENRHGTIFASAELSVIAVGPDFSKTLLKKLTLVKVGGEVIIECKPKASPRPTYSWKKGKDILRENERITVLDDGSLRIVNVTKSDTGSYTCVATNHFGTASSTGSLVVKDPTRVMVSPFSMDVTVGESIVLPCQVSHDHSLDIVFTWSFNGHLIDFEKDGDHFERVGGQDSAGDLMIRSIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEDVTIDEITDTTAQLSWRPGADNHSPITMYVVQARTPFSVGWQAVSTVPEVIDGKTFTATVVGLNPWVEYEFRVVAANLIGIGEPSRPSENRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGGGFGYVVAFRPFGTISWMQTVVASPDASRYVFRNESLPPFSPYEVKVGVYNNKGEGSFSPVTVVYSAEEEPTKAPITVLARSLSATDIEISWAPPRENQHKGRIQGYEVRCWRHDEKEENARKIRTVGNQTSAKVTNLQGNALYHLAVKAYNTAGTGPSSAMVNVTTKKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVRGYKVSVCQHRQWDCDHAQPPMGPAGSPDGALAVPILLHWVLMEMFAILY", "length": 986, "header": "tr|A0A8V0ZDA6-1|A0A8V0ZEQ2_CHICK Computationally mapped isoform of Contactin 4 OS=Gallus gallus OX=9031 GN=CNTN4 PE=3 SV=1 CANONICAL=A0A8V0ZEQ2-1" }, "locus": { "chromosome": "12", "start_pos": 18266268, "end_pos": 18145204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049404.1", "url": "https://www.ensembl.org/id/ENSGALT00010049404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029201.1", "url": "https://www.ensembl.org/id/ENSGALP00010029201.1" } ] } }, { "isoform_ac": "A0A8V0ZEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2/entry#A0A8V0ZEC2-1", "sequence": { "sequence": "MRLLWELLVLQSFMVCLADLENFKTRVRSTVSVRQGQGMVLLCGPPPHSGELTYAWIFNEYPSFVHQDNRRFVSQETGNLYIAKVEASDVGNYTCVVTNTVTNSRVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPSAKGTAVKLECFALGNPVPTISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDAGMYQCVAENRHGTIFASAELSVIAVGPDFSKTLLKKLTLVKVGGEVIIECKPKASPRPTYSWKKGKDILRENERITVLDDGSLRIVNVTKSDTGSYTCVATNHFGTASSTGSLVVKDPTRVMVSPFSMDVTVGESIVLPCQVSHDHSLDIVFTWSFNGHLIDFEKDGDHFERVGGQDSAGDLMIRSIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEDVTIDEITDTTAQLSWRPGADNHSPITMYVVQARTPFSVGWQAVSTVPEVIDGKTFTATVVGLNPWVEYEFRVVAANLIGIGEPSRPSENRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGGGFGYVVAFRPFGTISWMQTVVASPDASRYVFRNESLPPFSPYEVKVGVYNNKGEGSFSPVTVVYSAEEEPTKAPITVLARSLSATDIEISWAPPRENQHKGRIQGYEVRCWRHDEKEENARKIRTVGNQTSAKVTNLQGNALYHLAVKAYNTAGTGPSSAMVNVTTKKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVRGYKVLYKWNRQSSASVIETNRTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGGSSSTSNACTLSAISTIMISLTARSSL", "length": 928, "header": "tr|A0A8V0ZEC2-1|A0A8V0ZEC2_CHICK Computationally mapped isoform of Contactin 4 OS=Gallus gallus OX=9031 GN=CNTN4 PE=3 SV=1 CANONICAL=A0A8V0ZEQ2-1" }, "locus": { "chromosome": "12", "start_pos": 18268385, "end_pos": 18145204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049410.1", "url": "https://www.ensembl.org/id/ENSGALT00010049410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029203.1", "url": "https://www.ensembl.org/id/ENSGALP00010029203.1" } ] } }, { "isoform_ac": "A0A8V0ZEQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2/entry#A0A8V0ZEQ2-1", "sequence": { "sequence": "MRLLWELLVLQSFMVCLADDNMLHGPVFLQEPSSVIFPLDSEEKKVKLNCEVKGNPRPTIGWKLNGTNIDIGMDYRYSMVEGNLLINNPNRTQDTGTYQCVATNPFGRIISREAKLQFAYLENFKTRVRSTVSVRQGQGMVLLCGPPPHSGELTYAWIFNEYPSFVHQDNRRFVSQETGNLYIAKVEASDVGNYTCVVTNTVTNSRVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPSAKGTAVKLECFALGNPVPTISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDAGMYQCVAENRHGTIFASAELSVIAVGPDFSKTLLKKLTLVKVGGEVIIECKPKASPRPTYSWKKGKDILRENERITVLDDGSLRIVNVTKSDTGSYTCVATNHFGTASSTGSLVVKDPTRVMVSPFSMDVTVGESIVLPCQVSHDHSLDIVFTWSFNGHLIDFEKDGDHFERVGGQDSAGDLMIRSIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEDVTIDEITDTTAQLSWRPGADNHSPITMYVVQARTPFSVGWQAVSTVPEVIDGKTFTATVVGLNPWVEYEFRVVAANLIGIGEPSRPSENRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGGGFGYVVAFRPFGTISWMQTVVASPDASRYVFRNESLPPFSPYEVKVGVYNNKGEGSFSPVTVVYSAEEEPTKAPITVLARSLSATDIEISWAPPRENQHKGRIQGYEVRCWRHDEKEENARKIRTVGNQTSAKVTNLQGNALYHLAVKAYNTAGTGPSSAMVNVTTKKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVRGYKVLYKWNRQSSASVIETNRTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGGSSSTSNACTLSAISTIMISLTARSSL", "length": 1029, "header": "tr|A0A8V0ZEQ2-1|A0A8V0ZEQ2_CHICK Isoform 1 of Contactin 4 OS=Gallus gallus OX=9031 GN=CNTN4 PE=3 SV=1 CANONICAL=A0A8V0ZEQ2-1" }, "locus": { "chromosome": "12", "start_pos": 18268385, "end_pos": 18145204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049418.1", "url": "https://www.ensembl.org/id/ENSGALT00010049418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029207.1", "url": "https://www.ensembl.org/id/ENSGALP00010029207.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BE12-1", "protein_name": "Contactin 4", "gene_name": "CNTN4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPIFIQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDAGMYQCIATNSFGTIVSREAKLQFAYLENFKPRTRSTVSVRQGQGMVLLCGPPAHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNQKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGTTVKLECFALGNPVPTIIWRRADGKPIATKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVAKGQLTFYAQPNWSQKINDIHVAIEENVFWECKANGRPKPTYRWLKNGEPLLTRDRIHIEQGTLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVHTWKKGRDVLKENERITISEDGSLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLNIVFTWSFNGRLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYICMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPMEKNRGRIQGYEVKYWRHDDKEENARKIRTIGNQTSTKITNLKGSALYHLAVKAYNSAGTGPASATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWSRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGAGPSTSNACTLSAISTIMISLTARSSL", "length": 1026 }, "evidence": [ { "id": "A0A8V0ZEQ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEQ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62845-1", "protein_name": "Contactin-4", "gene_name": "Cntn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLPWELLVLQSFMLCLADDYTLHGPVFVQEPSHVMFPLDSEEKKVKLSCEVKGNPKPHIRWKLNGTDVDIGMDFRYSVVEGSLLINNPNKTQDSGTYQCIATNSFGTIVSREAKLQFAYLENFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEHPSYQDNRRFVSQETGNLYIAKVEKADVGNYTCVVTNTVTSHQVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPAEKGSTVKLECFALGNPVPTILWRRADGKPIARKARRHKSSGILEIPNFQQEDAGSYECVAENSRGKNIAKGQVTFYAQPNWVQIINDIHVAMEESVFWECKANGRPKPTYRWLKNGDPLLTRERIQIEQGTLNITIVNLSDAGMYQCVAENKHGVIYASAELSVIAESPDFSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNVVVKDPTKVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFARSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENARKIRTVGNQTSTKITNLKGNALYHLSVKAYNSAGTGPSSAAVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIMISLTARSSL", "length": 1026 }, "evidence": [ { "id": "A0A8V0ZEQ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWV2-1", "protein_name": "Contactin-4", "gene_name": "CNTN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL", "length": 1026 }, "evidence": [ { "id": "A0A8V0ZEQ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZEQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "negative regulation of neuron differentiation", "id": "GO:0045665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 896, "end_pos": 898, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 601, "end_pos": 699, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZEQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEQ2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 117, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 707, "end_pos": 709 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 861, "end_pos": 863 }, { "start_pos": 896, "end_pos": 898 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 932, "end_pos": 934 }, { "start_pos": 957, "end_pos": 959 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDA8-1", "uniprot_ac": "A0A8V0ZDA8", "uniprot_id": "A0A8V0ZDA8_CHICK", "mass": { "chemical_mass": 124117.0, "monoisotopic_mass": 124117.0 }, "refseq": {}, "gene_names": [ { "name": "MYO1H", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ] } ], "protein_names": [ { "name": "Myosin IH", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYO1H", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8", "locus": { "chromosome": "15", "start_pos": 6749141, "end_pos": 6708849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021559", "url": "https://www.ensembl.org/id/ENSGALG00010021559" } ] } } ], "crossref": [ { "id": "A0A8V0ZDA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768372", "url": "https://www.ncbi.nlm.nih.gov/gene/768372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768372", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEIYQGV", "url": "https://omabrowser.org/oma/group/MEIYQGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKH5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR73", "url": "https://www.orthodb.org/?gene=A0A8V0ZR73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR78", "url": "https://www.orthodb.org/?gene=A0A8V0ZR78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR90", "url": "https://www.orthodb.org/?gene=A0A8V0ZR90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAASLLWEHGHHATAVKIQRSSWCNFSSVCGMECEDSTARMPAEKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1077, "header": "tr|A0A8V0ZDA8-1|A0A8V0ZDA8_CHICK Isoform 1 of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZDA8-1", "sequence": { "sequence": "MHAASLLWEHGHHATAVKIQRSSWCNFSSVCGMECEDSTARMPAEKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1077, "header": "tr|A0A8V0ZDA8-1|A0A8V0ZDA8_CHICK Isoform 1 of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6721982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052330.1", "url": "https://www.ensembl.org/id/ENSGALT00010052330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031268.1", "url": "https://www.ensembl.org/id/ENSGALP00010031268.1" } ] } }, { "isoform_ac": "A0A8V0ZIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZIU8-1", "sequence": { "sequence": "MEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1021, "header": "tr|A0A8V0ZIU8-1|A0A8V0ZIU8_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6734198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052349.1", "url": "https://www.ensembl.org/id/ENSGALT00010052349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031280.1", "url": "https://www.ensembl.org/id/ENSGALP00010031280.1" } ] } }, { "isoform_ac": "A0A8V0ZKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZKE9-1", "sequence": { "sequence": "MDTQKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1036, "header": "tr|A0A8V0ZKE9-1|A0A8V0ZKE9_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6723031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052338.1", "url": "https://www.ensembl.org/id/ENSGALT00010052338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031272.1", "url": "https://www.ensembl.org/id/ENSGALP00010031272.1" } ] } }, { "isoform_ac": "A0A8V0ZKF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZKF4-1", "sequence": { "sequence": "MDTQKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGRCQTRQSLDEKQFQFLVTRNGKEPAG", "length": 1021, "header": "tr|A0A8V0ZKF4-1|A0A8V0ZKF4_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748989, "end_pos": 6723031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052344.1", "url": "https://www.ensembl.org/id/ENSGALT00010052344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031277.1", "url": "https://www.ensembl.org/id/ENSGALP00010031277.1" } ] } }, { "isoform_ac": "A0A8V0ZKH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZKH5-1", "sequence": { "sequence": "MFLLYSAPPDLTVHLFSSMTLSHEKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1018, "header": "tr|A0A8V0ZKH5-1|A0A8V0ZKH5_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6730458, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052318.1", "url": "https://www.ensembl.org/id/ENSGALT00010052318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031256.1", "url": "https://www.ensembl.org/id/ENSGALP00010031256.1" } ] } }, { "isoform_ac": "A0A8V0ZR73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZR73-1", "sequence": { "sequence": "MSYGNMEEVRKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1042, "header": "tr|A0A8V0ZR73-1|A0A8V0ZR73_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6726425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052321.1", "url": "https://www.ensembl.org/id/ENSGALT00010052321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031259.1", "url": "https://www.ensembl.org/id/ENSGALP00010031259.1" } ] } }, { "isoform_ac": "A0A8V0ZR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZR78-1", "sequence": { "sequence": "MSYGNMEEVRKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 982, "header": "tr|A0A8V0ZR78-1|A0A8V0ZR78_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6726425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052326.1", "url": "https://www.ensembl.org/id/ENSGALT00010052326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031264.1", "url": "https://www.ensembl.org/id/ENSGALP00010031264.1" } ] } }, { "isoform_ac": "A0A8V0ZR90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8/entry#A0A8V0ZR90-1", "sequence": { "sequence": "MTAVKIQRSSWCNFSSVCGMECEDSTARMPAEKEEVEDNTDIIMEGALIARDRVGVQDFVLLDSHTSEAAFLNNLRKRYQENLIYTYIGTLLVSVNPYKELDIYTVTQMQLYRGVNFFELPPHLYAIADNAYRVMCSEYNNHFILISGESGAGKTEASKKILQYYAVTCPTTEQLQVVRDRLLLSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILSYLIEKSRVVHQNHGERNFHIFYQLLEGGEKDLLSWLGLERNPQKYAYLVQGRCAKVFSINDKNDWKIVRKAFSIIDFTEKDLEHLFGIVASVLHLGNIQFEEDSNGHAIIRNGTQIKWISKLLGVHLSILQEALTHRKIEARSEEVLSPLNVDLAFYARDAVAKAIYGRTFTWLVNKINGSLANKDSTRKTVIGLLDIYGFEVLDTNSFEQFCINYCNEKLQQLLIEMTLKAEQEEYEMEGIEWEPIPYFNNKIICDLVEQKHKGIISILDEECLRPGEATDLSFLEKLEEKVGDHAHFVTRKLADQKTRKSIDWVDFRLLHYAGEVTYCAVGFLEKNNDLLYRNLKEVLCNSKNGIVRECFLLSELDSRRRPETVATQFKNSLMSLIEILMSKEPSYVRCIKPNENKEPGKFDDCLIRHQVKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPATWPHWHGPAAEGVERLIKHIGYKPEEYKLGRTKIFIRFPKTLFATEDAFEIRKHLLVSRLQAKYKGRLGKRDYQKKRKAAIKLEACWRGVLARKEAKKRTWAVQIIRKFIKGFINRKKPLCPENTEFVRLVQYKYLMKLRDHIPRNVLDKSWLQPPSILEEISEMLQKICIRNLVQKYCRGVTPERKVQLQQKAVTSAIFRGKKEGYQQSINLPFADTRLKETDISPKVLQLIQGEKVKYATPVVKYDRNGFKARERLLVLTQSSAYVVEMAKIKQKIDYATLKGISTSNLCDGIVVIHVPEDNKQKGDVILQCEHIFETVTKLCMLANKQNLVKVVKGSLRFRIGSGKEGTMVFTVGPEPHVFKAKDGQLTVVSNQAKS", "length": 1064, "header": "tr|A0A8V0ZR90-1|A0A8V0ZR90_CHICK Computationally mapped isoform of Myosin IH OS=Gallus gallus OX=9031 GN=MYO1H PE=3 SV=1 CANONICAL=A0A8V0ZDA8-1" }, "locus": { "chromosome": "15", "start_pos": 6748934, "end_pos": 6709178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052347.1", "url": "https://www.ensembl.org/id/ENSGALT00010052347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031279.1", "url": "https://www.ensembl.org/id/ENSGALP00010031279.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:768372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768372", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R829-1", "protein_name": "Myosin IH", "gene_name": "Myo1h", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSKKEEVRRKHIRLHMEGALTARDKVGVQDFVLLDAYTSESAFLENLRKRFRENLIYTYIGTLLVSVNPYQELGIYTSSQMELYQGVNFFELPPHVYAIADNAYRMMCSELNNHFILISGESGAGKTEASKKILQYLAVTCPMTESLQIARDRLLLSIPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFQGVPVGGHIISYLIEKSRVVYQNHGERNFHIFYQLLAGGKSERLASLGLERDPQLYKFLSQGHCARESPSNDRSDWETVYSAFSVIGFTEADLENLFGIIASVLHLGNICFKGDKQGCASIPDTHEIKWIAKLLGVCPAVLLEALTHRKIEAKTEEVICPLTVELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTQKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYESEGIEWEPVQYFNNKIICDLVEERHRGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFQTRKLAGPKGRKRIGWLEFCLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCSSKNSILRECFLVAELENRKRPPTVGTQFKNSLSSLLEILISKEPSYIRCIKPNERKEPSKFDDFLISHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPGEGVERLIKYIGYQPQDYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVSRIQATYKGCLGRREYVRKRQAATKLEAHWRGVLARKEIKRRKWAVQIIRRFIKGFINRDKPLCPDNEEFLLLVRKNYILNLRYHVPKNVLDKSWLRPPGILENASNLLRRMCTRNLVRKYCRGISAERKAMMQQKAVTSGLFRGKKEGYAESLSQPFASSRLDEGKINPKVLQLLGSEKIQYGVPVIKYDRKGFKARQRQLLLTLRSAYLVEFSKIKQKMEYSALRGVSTSSLRDGILVIHVSPADKQQKGDTILQCEHIFEVATKLAMLIKREHVVRVVQGSLQFCVSPGREGTIVFETGEEDQVYKDKNGQLRVVSAGKKT", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZDA8", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N1T3-1", "protein_name": "Unconventional myosin-Ih", "gene_name": "MYO1H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKVGQRILDPLLLLTWKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSVRRKS", "length": 1032 }, "evidence": [ { "id": "A0A8V0ZDA8", "url": "https://omabrowser.org/oma/group/A0A8V0ZDA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDB9-1", "uniprot_ac": "A0A8V0ZDB9", "uniprot_id": "A0A8V0ZDB9_CHICK", "mass": { "chemical_mass": 56228.0, "monoisotopic_mass": 56228.0 }, "refseq": {}, "gene_names": [ { "name": "TADA3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9" } ] } ], "protein_names": [ { "name": "Transcriptional adaptor 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TADA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9", "locus": { "chromosome": "12", "start_pos": 11662287, "end_pos": 11664963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021568", "url": "https://www.ensembl.org/id/ENSGALG00010021568" } ] } } ], "crossref": [ { "id": "A0A8V0ZDB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDB3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13556", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13556", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13556:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13556:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSELKDCPLQFHDFKSVDHVKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRRFLKLSKDHDVGTSVKHGKPKKQKLEGKGGHGTGPGPGRPKSKNLQPKIQEYEFQDDPIDVPRIPKNDAPNRFWASVEPYCADLTNEEVRVLEELLKPPEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAAADKKKGVLGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGPLTQRLLQALVEVRGFGSAQWPCEALSLHQGEVNLSHVLCLPGKHHLPCGGLAHSRDCWQGLRSRRRWHFSPQPEQALQVSCCGAAKLGAAWCFPCHNRGRTLGASKSILSAPRSVPHTKSLEGRIKEELVAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRAKKHELLRLAKEELHRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG", "length": 498, "header": "tr|A0A8V0ZDB9-1|A0A8V0ZDB9_CHICK Isoform 1 of Transcriptional adaptor 3 OS=Gallus gallus OX=9031 GN=TADA3 PE=3 SV=1 CANONICAL=A0A8V0ZDB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9/entry#A0A8V0ZDB3-1", "sequence": { "sequence": "ERAEGLPVAVPRLQVGGPREGVPALHGRARPLRGRWHRHRGAGHAAAGAGDAALLRQPPPPCPGGRDTGVSPVSATPVSPSPSCTRPRRTIALFQILTDWQDKKGDRRFLKLSKDHDVGTSVKHGKPKKQKLEGKGGHGTGPGPGRPKSKNLQPKIQEYEFQDDPIDVPRIPKNDAPNRFWASVEPYCADLTNEEVRVLEELLKPPEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAAADKKKGVLGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGPLTQRLLQALVEENIISPVEDSPIPEIAGKDSGADGAGTSPRSQNKPFSVPHTKSLEGRIKEELVAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRAKKHELLRLAKEELHRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG", "length": 458, "header": "tr|A0A8V0ZDB3-1|A0A8V0ZDB9_CHICK Computationally mapped isoform of Transcriptional adaptor 3 OS=Gallus gallus OX=9031 GN=TADA3 PE=3 SV=1 CANONICAL=A0A8V0ZDB9-1" }, "locus": { "chromosome": "12", "start_pos": 11664883, "end_pos": 11662794, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052340.1", "url": "https://www.ensembl.org/id/ENSGALT00010052340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031273.1", "url": "https://www.ensembl.org/id/ENSGALP00010031273.1" } ] } }, { "isoform_ac": "A0A8V0ZDB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB9/entry#A0A8V0ZDB9-1", "sequence": { "sequence": "MSELKDCPLQFHDFKSVDHVKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRRFLKLSKDHDVGTSVKHGKPKKQKLEGKGGHGTGPGPGRPKSKNLQPKIQEYEFQDDPIDVPRIPKNDAPNRFWASVEPYCADLTNEEVRVLEELLKPPEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAAADKKKGVLGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGPLTQRLLQALVEVRGFGSAQWPCEALSLHQGEVNLSHVLCLPGKHHLPCGGLAHSRDCWQGLRSRRRWHFSPQPEQALQVSCCGAAKLGAAWCFPCHNRGRTLGASKSILSAPRSVPHTKSLEGRIKEELVAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRAKKHELLRLAKEELHRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG", "length": 498, "header": "tr|A0A8V0ZDB9-1|A0A8V0ZDB9_CHICK Isoform 1 of Transcriptional adaptor 3 OS=Gallus gallus OX=9031 GN=TADA3 PE=3 SV=1 CANONICAL=A0A8V0ZDB9-1" }, "locus": { "chromosome": "12", "start_pos": 11664885, "end_pos": 11662794, "strand": "+", "evidence": [ { "database": "Ensembl 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"421424", "url": "https://www.ncbi.nlm.nih.gov/gene/421424", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YWNWPNA", "url": "https://omabrowser.org/oma/group/YWNWPNA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZJH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKAKQIIREVSKQTVFLGSFLPLATSLNINPSPCYSYKTSCPSCCWKPALPCLLLLQSDGKYRESSVVVSNAADQGVAITGNNTFNNWNWPNAVIFAATVITTIGYGNVSPKTPSGRLFCIFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEGWDYIEGLYYSFITITTIGFGDFVAGVNPDANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRKKRKESFDSHPRSKKPLQMGASKDVNIFSFLSKKEETYNDLIKQIGKKALKTNNDKMIKVENTKQNMQNAIKDAQVTYTKSEAFEYDESSLDIQNDHVLRHLHDKRIGDSPIEGTMFVNQLDRISEEEGEVWDSRDYRPLIFENANITFVNEDDDEEEDISDDEETSKSSMDDNTVEEPDTAKNLVKFSSSDESTFTNNELELSVPYEQLMNEYNTVSNVKAAT", "length": 490, "header": "tr|A0A8V0ZDG7-1|A0A8V0ZDG7_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 5 OS=Gallus gallus OX=9031 GN=KCNK5 PE=3 SV=1 CANONICAL=A0A8V0ZDG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7/entry#A0A8V0ZDG7-1", "sequence": { "sequence": "MDKAKQIIREVSKQTVFLGSFLPLATSLNINPSPCYSYKTSCPSCCWKPALPCLLLLQSDGKYRESSVVVSNAADQGVAITGNNTFNNWNWPNAVIFAATVITTIGYGNVSPKTPSGRLFCIFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEGWDYIEGLYYSFITITTIGFGDFVAGVNPDANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRKKRKESFDSHPRSKKPLQMGASKDVNIFSFLSKKEETYNDLIKQIGKKALKTNNDKMIKVENTKQNMQNAIKDAQVTYTKSEAFEYDESSLDIQNDHVLRHLHDKRIGDSPIEGTMFVNQLDRISEEEGEVWDSRDYRPLIFENANITFVNEDDDEEEDISDDEETSKSSMDDNTVEEPDTAKNLVKFSSSDESTFTNNELELSVPYEQLMNEYNTVSNVKAAT", "length": 490, "header": "tr|A0A8V0ZDG7-1|A0A8V0ZDG7_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 5 OS=Gallus gallus OX=9031 GN=KCNK5 PE=3 SV=1 CANONICAL=A0A8V0ZDG7-1" }, "locus": { "chromosome": "3", "start_pos": 28908702, "end_pos": 28890002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048659.1", "url": "https://www.ensembl.org/id/ENSGALT00010048659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028750.1", "url": "https://www.ensembl.org/id/ENSGALP00010028750.1" } ] } }, { "isoform_ac": "A0A8V0ZDH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7/entry#A0A8V0ZDH2-1", "sequence": { "sequence": "MVDRGPLLTSAIIFYLSIGAAIFEVLEEPHWRSATDDYKRQKTELLKQFPCLGQEGLDKILQVVSNAADQGVAITGNNTFNNWNWPNAVIFAATVITTIGYGNVSPKTPSGRLFCIFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEGWDYIEGLYYSFITITTIGFGDFVAGVNPDANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRKKRKESFDSHPRSKKPLQMGASKDVNIFSFLSKKEETYNDLIKQIGKKALKTNNDKMIKVENTKQNMQNAIKDAQVTYTKSEAFEYDESSLDIQNDHVLRHLHDKRIGDSPIEGTMFVNQLDRISEEEGEVWDSRDYRPLIFENANITFVNEDDDEEEDISDDEETSKSSMDDNTVEEPDTAKNLVKFSSSDESTFTNNELELSVPYEQLMNEYNTVSNVKAAT", "length": 484, "header": "tr|A0A8V0ZDH2-1|A0A8V0ZDH2_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 5 OS=Gallus gallus OX=9031 GN=KCNK5 PE=3 SV=1 CANONICAL=A0A8V0ZDG7-1" }, "locus": { "chromosome": "3", "start_pos": 28908702, "end_pos": 28879650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048664.1", "url": "https://www.ensembl.org/id/ENSGALT00010048664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028755.1", "url": "https://www.ensembl.org/id/ENSGALP00010028755.1" } ] } }, { "isoform_ac": "A0A8V0ZJH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7/entry#A0A8V0ZJH9-1", "sequence": { "sequence": "MPCTQGCSQSLPRDSTLGNFFHSHKELIIVSFPIWQNASSKLIVNRYRVVVSNAADQGVAITGNNTFNNWNWPNAVIFAATVITTIGYGNVSPKTPSGRLFCIFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEGWDYIEGLYYSFITITTIGFGDFVAGVNPDANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRKKRKESFDSHPRSKKPLQMGASKDVNIFSFLSKKEETYNDLIKQIGKKALKTNNDKMIKVENTKQNMQNAIKDAQVTYTKSEAFEYDESSLDIQNDHVLRHLHDKRIGDSPIEGTMFVNQLDRISEEEGEVWDSRDYRPLIFENANITFVNEDDDEEEDISDDEETSKSSMDDNTVEEPDTAKNLVKFSSSDESTFTNNELELSVPYEQLMNEYNTVSNVKAAT", "length": 471, "header": "tr|A0A8V0ZJH9-1|A0A8V0ZJH9_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 5 OS=Gallus gallus OX=9031 GN=KCNK5 PE=3 SV=1 CANONICAL=A0A8V0ZDG7-1" }, "locus": { "chromosome": "3", "start_pos": 28908702, "end_pos": 28880437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048662.1", "url": "https://www.ensembl.org/id/ENSGALT00010048662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028753.1", "url": "https://www.ensembl.org/id/ENSGALP00010028753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BNW6-1", "protein_name": "Potassium two pore domain channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKVHLLKEFPCLGQDGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTAIFILWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVASGAASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERGPGPGPPRAGLPALPASLTPLVVYSKSQVPSLEEVSQTLRSKGHVSRPSGEEAGAGPPEEGSPTSEVFINQLDRISEEGEPWDAQDYHPLIFQNADITFANEEAGLLDEDTSKSSLEDNLAGEERPQEGATAEAPLNLGEFPSSDESTFTSTESELSVPYEQLMNEYNKAKCPEGT", "length": 497 }, "evidence": [ { "id": "A0A8V0ZDG7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDG7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RVQ9-1", "protein_name": "Potassium two pore domain channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKTNYYTQKLRLLKEFPCLGQEGLDKILQIVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQIACTAIFIVWGVLVHLVIPPFVFMVTEEWDYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVAGSTAAKDINIFSFLSKKEETYNDLIKQIGKKAMKTGGGGERIPGPGPQGGGLPALPSSLAPLAVYSKNRVPSLEEVSQTLRTKGHISRPPGEEAVAGGPKEVSPTSEVSINQLDRISEEGEPWDAQDYHPLIFQNANITFVSAEAGLSDEETSKSSLEDNLAQEERPQEGAVAEAPLTLGEFPSSDESTFTSTESELSVPYEQLMNEYNKASGPQGT", "length": 497 }, "evidence": [ { "id": "A0A8V0ZDG7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I2N9-1", "protein_name": "Potassium channel subfamily K member 5", "gene_name": "Kcnk5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLSQEGLDKILQVVSVAADQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTRRGVSLRKAQITCTAIFIVWGVLVHLVIPPFVFMVTEEWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQMASSSASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGERVPGPGHGLGAQGDGLSNIPASLVPLVVYSKTRVPSLEEVSQTLRSKGHVSRPVGAEAEVKYPKDGYPTSEVFVNQLDRISEEGEPWEALDYHPLILQNANITFENEETGLSDEETSKSSVEDNLASKEQPQQRTVAEVPLSTGEFPSSDESTFTSTESELSVPYEQLMNEYNKADSPRGT", "length": 501 }, "evidence": [ { "id": "A0A8V0ZDG7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDG7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95279-1", "protein_name": "Potassium channel subfamily K member 5", "gene_name": "KCNK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQTLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASITFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELSVPYEQLMNEYNKANSPKGT", "length": 499 }, "evidence": [ { "id": "A0A8V0ZDG7", "url": "https://omabrowser.org/oma/group/A0A8V0ZDG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG7" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 143, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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42661.0, "monoisotopic_mass": 42661.0 }, "refseq": { "ac": "XP_024998720", "name": "lysophosphatidic acid receptor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998720" }, "gene_names": [ { "name": "LPAR5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0" } ] }, { "name": "LPAR5", "type": "synonym", "evidence": [ { "id": "XP_024998720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998720" } ] } ], "protein_names": [ { "name": "Lysophosphatidic acid receptor 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0/entry#names_and_taxonomy" } ] }, { "name": "lysophosphatidic acid receptor 5", "type": "synonym", "evidence": [ { "id": "XP_024998720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998720" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024998720.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998720" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LPAR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0", "locus": { "chromosome": "1", "start_pos": 76974268, "end_pos": 76989841, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021601", "url": "https://www.ensembl.org/id/ENSGALG00010021601" } ] } } ], "crossref": [ { "id": "cd15154", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15154", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418279", "url": "https://www.ncbi.nlm.nih.gov/gene/418279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418279", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTCKDYT", "url": "https://omabrowser.org/oma/group/QTCKDYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-419408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024998720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAANVSQPCKDYSFYHKLLLPGYILIFITGLTLNVMALWIFVRYLRLKSVVMIYMFNLAVSDLTFTLPLPLRLYYYFNHEWPFGNTLCQVSGSVFQINMYGSCIFLMCINLDRYIAIVHPLRWRHLRRPKVARLLCLVVWVVILMGSIPTAIVHKQNHCESQNQTTYLCFESFSDNMWQKNLFPLVVLAEILGFLLPLSAVTYCSIQIFRELCQTRQPKTLRQQKTVRLLLVNLVIFVIFFVPYNTTLAVYGLIKARVIDVEKQMQASVREVLIVTMMLASMNCTLDPLIYYFSTEGFRNTFKKLRRGQTWHSDTGVIRNQVVEQKSTRNHAASTAKQLPSENFHCPGEAVPALPTTVFLNGPIEDSEI", "length": 370, "header": "tr|A0A8V0ZDJ0-1|A0A8V0ZDJ0_CHICK Isoform 1 of Lysophosphatidic acid receptor 5 OS=Gallus gallus OX=9031 GN=LPAR5 PE=3 SV=1 CANONICAL=A0A8V0ZDJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0/entry#A0A8V0ZDJ0-1", "sequence": { "sequence": "MSAANVSQPCKDYSFYHKLLLPGYILIFITGLTLNVMALWIFVRYLRLKSVVMIYMFNLAVSDLTFTLPLPLRLYYYFNHEWPFGNTLCQVSGSVFQINMYGSCIFLMCINLDRYIAIVHPLRWRHLRRPKVARLLCLVVWVVILMGSIPTAIVHKQNHCESQNQTTYLCFESFSDNMWQKNLFPLVVLAEILGFLLPLSAVTYCSIQIFRELCQTRQPKTLRQQKTVRLLLVNLVIFVIFFVPYNTTLAVYGLIKARVIDVEKQMQASVREVLIVTMMLASMNCTLDPLIYYFSTEGFRNTFKKLRRGQTWHSDTGVIRNQVVEQKSTRNHAASTAKQLPSENFHCPGEAVPALPTTVFLNGPIEDSEI", "length": 370, "header": "tr|A0A8V0ZDJ0-1|A0A8V0ZDJ0_CHICK Isoform 1 of Lysophosphatidic acid receptor 5 OS=Gallus gallus OX=9031 GN=LPAR5 PE=3 SV=1 CANONICAL=A0A8V0ZDJ0-1" }, "locus": { "chromosome": "1", "start_pos": 76978670, "end_pos": 76977561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052439.1", "url": "https://www.ensembl.org/id/ENSGALT00010052439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031346.1", "url": "https://www.ensembl.org/id/ENSGALP00010031346.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418279", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-GGA-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABI5-1", "protein_name": "Lysophosphatidic acid receptor 5", "gene_name": "LPAR5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLANFTNPLTSGPVFKCPDHQSTHRLHLVVYSLVLATGLPLNALALWVFLRELRVHSVVSVYMCNLAASDLLFTLSLPLRLSYYARHYWPFSDLLCQLASAVFQMNMYGSCIFLTLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPTVLAHRPSSCIRNDSHEVHLCFENFSDELWKGRLLPLLLLAEALGFLLPLAAVVYSSGCVFWTLARPDATRSHRRRKTVRLLLASLVIFLLCFVPYNATLAVYGLLRGNVVPASTSAREQVREVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLSTPLRTRTSATTPPEQPAEPAHAIGTGTAASQGLLGPSKLGSSFTQCPEDSCL", "length": 367 }, "evidence": [ { "id": "A0A8V0ZDJ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZDJ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADR1-1", "protein_name": "Lysophosphatidic acid receptor 5", "gene_name": "Lpar5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQTSFSPHLDAMFANSSANTSSTDSSVPQCRDYRSTHRLHMVVYSLVLATGLPLNALALWVFLRVLRVHSVVSVYMCNLAASDLLFTLSLPLRLSYYARHHWPFPDFLCQTSGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPLVARRLCLGVWALILLFAVPAARVHSPTTCKYENVTLSLCFESFSDELWKGRLLPLLLLAETLGFLLPLAAVVYSSGRVFWTLARPDATQSHRRQKTVRLLLANLIIFLLCFVPYNSTLAVYGLLRANLVKNSLQARDQVRGVLMIMVLLAGANCVLDPLVYYFSAEGFRNTLRNLGAPFHTRPLPTNGTRGELTEPPSESTQNTGQDATSQRLLQPANLGTRTDNGPQDSAL", "length": 384 }, "evidence": [ { "id": "A0A8V0ZDJ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZDJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q149R9-1", "protein_name": "Lysophosphatidic acid receptor 5", "gene_name": "Lpar5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFANSSANTTSTNSSVLQCPDYRDTHRLHMVVYSLVLATGLPLNALALWVFLRVLRVHSVVSVYMCNLAASDLLFTLSLPLRLSYYAQHHWPFPGFLCQTSGAIFQMNMYGSCLFLMLINVDRYAAIVHPLRLRHLRRPRVARRLCLGVWALILLFAVPAARVHSPSHCTYKNITVRLCFESFSDELWKGRLLPLLLLAEILGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLIIFLLCFVPYNSTLAVYGLLRANLVKNSIQDRDQVRGVLMIMVLLAGANCVLDPLVYYFSAEGFRNTLRNLGAPLNTRPLATNGAAGVLTELPSESTQNTGQDATSQVLLQPATLGTPPDNCSQDSAL", "length": 372 }, "evidence": [ { "id": "A0A8V0ZDJ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZDJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZC80-1", "protein_name": "Lysophosphatidic acid receptor 5", "gene_name": "LPAR5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQANSSAKSLPTECPDYQPIHHLHLVVYSVVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPLRLSYYARHYWPFPDFLCQLAGAVFQMNMYGSCIFLTLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPTILAHQPSSCARDGRNVSLCFESFSDKLWKGSLLPLLLLAEALGFLLPLAAVVYSSGRVFWTLARPDATRSQRRRKTVRLLLASLVIFLLCFVPYNATLAVYGLLRGEVVPASSEARKKVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLRAPLRDRTLAANGAQEALAEPLTETAHASTLTTTSQGQLQPSDPRSSFTPSHEDSSF", "length": 367 }, "evidence": [ { "id": "A0A8V0ZDJ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZDJ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9H1C0-1", "protein_name": "Lysophosphatidic acid receptor 5", "gene_name": "LPAR5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL", "length": 372 }, "evidence": [ { "id": "A0A8V0ZDJ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZDJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "behavioral response to pain", "id": "GO:0048266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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} ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024998564.1. 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"end_pos": 82, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDQ6-1", "uniprot_ac": "A0A8V0ZDQ6", "uniprot_id": "A0A8V0ZDQ6_CHICK", "mass": { "chemical_mass": 34495.0, "monoisotopic_mass": 34495.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": 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"MPTSWLLRSPWSRRVIPSPMADFMRRDSDGSTLMGGYICGAHSAMGVPLPCGPMGVPLPYSAMGVPPPYGPMGVPLPCGPMGVPPPYSAMGVPPPYSAMGVPLPYSAMGVPPPYSAMGVPLPYSAMGVPPPYSAMGVPPPYGPMGVPLPYSAMGVPLPCGPMGVPPPYSTMGVPLPCGPMGVPLPCGPMGVPPPYSAMGVPLPYSAMGVPPPCGPMGVPLPYSAMGVPLPCGPMGVPLPYSAMGVPLPCGPMGVPLPYSHYGGSHGPTALCGIPGTHSPMGDPRDVQPYRACRAIWDPRAIQPYRTRTAIQPYRAPTAIGIPRPYSPIGSQGHTAL", "length": 336, "header": "tr|A0A8V0ZDQ6-1|A0A8V0ZDQ6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ6/entry#A0A8V0ZDQ6-1", "sequence": { "sequence": "MPTSWLLRSPWSRRVIPSPMADFMRRDSDGSTLMGGYICGAHSAMGVPLPCGPMGVPLPYSAMGVPPPYGPMGVPLPCGPMGVPPPYSAMGVPPPYSAMGVPLPYSAMGVPPPYSAMGVPLPYSAMGVPPPYSAMGVPPPYGPMGVPLPYSAMGVPLPCGPMGVPPPYSTMGVPLPCGPMGVPLPCGPMGVPPPYSAMGVPLPYSAMGVPPPCGPMGVPLPYSAMGVPLPCGPMGVPLPYSAMGVPLPCGPMGVPLPYSHYGGSHGPTALCGIPGTHSPMGDPRDVQPYRACRAIWDPRAIQPYRTRTAIQPYRAPTAIGIPRPYSPIGSQGHTAL", "length": 336, "header": "tr|A0A8V0ZDQ6-1|A0A8V0ZDQ6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDQ6-1" }, "locus": { "chromosome": "4", "start_pos": 90316707, "end_pos": 90314972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044757.1", "url": "https://www.ensembl.org/id/ENSGALT00010044757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026679.1", "url": "https://www.ensembl.org/id/ENSGALP00010026679.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDR0-1", "uniprot_ac": "A0A8V0ZDR0", "uniprot_id": "A0A8V0ZDR0_CHICK", "mass": { "chemical_mass": 180317.0, "monoisotopic_mass": 180317.0 }, "refseq": { "ac": "XP_015142604", "name": "mitogen-activated protein kinase-binding protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142604" }, "gene_names": [ { "name": "WDR62", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ] }, { "name": "WDR62", "type": "synonym", "evidence": [ { "id": "XP_015142604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142604" } ] } ], "protein_names": [ { "name": "WD repeat domain 62", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase-binding protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015142604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142604" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142604.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142604" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0", "locus": {} } ], "crossref": [ { "id": "771487", "url": "https://www.ncbi.nlm.nih.gov/gene/771487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771487", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZJR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44813", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44813", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44813:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44813:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1638, "header": "tr|A0A8V0ZDR0-1|A0A8V0ZDR0_CHICK Isoform 1 of WD repeat domain 62 OS=Gallus gallus OX=9031 GN=WDR62 PE=4 SV=1 CANONICAL=A0A8V0ZDR0-1" }, "locus": { "chromosome": "5", "start_pos": 24651642, "end_pos": 24562793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048794.1", "url": "https://www.ensembl.org/id/ENSGALT00010048794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028845.1", "url": "https://www.ensembl.org/id/ENSGALP00010028845.1" } ] } }, { "isoform_ac": "A0A8V0ZJR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0/entry#A0A8V0ZJR8-1", "sequence": { "sequence": "MMSVEGSTITSRIKNLLRSPSIKLRRSKPGNKREDIGNKVTLEKVLGITVSGGRGLACDPRTGLVAYPAGCVVVLFNPRKNKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAERTQVAELQEHKYGVACVAFSPSSKYIVSVGYQHDMIVNVWSWKKNIVVAANKVSSKVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNFFADVACGRGKKADSTFCITSSGLLCEFNEKRLLDKWVELRTTVANCISVNHDYIFCGCADGTVRIFNPLNLHFVTTLPKPHFLGTDIASVTEASRLFSGTADAKYPDTIALTFDPTNQWLSCVYNDHSLYVWDVKDPKKVGKVYSALYHSSCVWNVEMYPEVKDSNQSCLPPGSFITCSSDNTIRLWNTESSNIHGTALHRNILSNDLMKIIYVDDNTQVLLDTDYNSGGSADKADTQVMDTKVGIRTVCVSPSGEHLASGDRIGTLRIYELQSLQEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGKDYSLQQTLDEHSSSITSVKFAANDGKVRMISCGADKSIYFRTAQKTGEGVQFTRTHHIVRKTTLYDMDVDPSWKYAAIGCQDRNIRVFNISSGKQKKLYKGSQGEDGTLIKVQTDPSGLYIATSCSDKNLSIFDFYSGECVATMYGHSEIVTGMKFSNDCKHLISVSGDSCIFIWRLSSEMTINMRQRLSDMKQRGKQAEKSPPHKTAGLMRHESISALSSVPALSSDSDKDGEDEGNDEDELSGLQSFHVQSNCNTERDSDPDLTLSRSLSHWEMRRAKEIAAIQRSEAPMSKVPRQRGRWSQPTNNIEMTVKSMLDLRQLESFSVSRSPSRDSLSQNSNGDDREEQADLPTHINKVGSSIAPQDNRSCVRPQVIRLLSCEEGIFSQELEPSESEECVIYPEQDEIHPTDPRSEYQVKALPHGKLNRSYQSNGCPDKHSPDSACSVDYSSSRLSSPDHPNEDSESTEPLSVDGISDLEGEEGEEDVGTSVPVGEIPQAPDQEKFLKQHFGTLGSTDGKGGSCRSLERTENLSISSRFLSQSPALRRLSLSSSNLILDSKSIESPAPTSRFTQDLLKNDSSHPADALENSHLLNNVNLHQAVYAQKKRKSALETSRVGMAPGRVIASFPEGPVNAVMRKAQSVHDLVHEDKGPGVVSSAKQRPHTLMVVEKDPRPNNCRALSSSLLKMDGSGALLAKDVRAAKPKSYMNPTTSFRAKMSRSISVGENLYLGYSTDVLTDGRTSPPVAEKTQFSPTADAEKMKLTGKENYPVKPALQPVVNCSSPKSFHSKLASSNRAHLILDIPKPLPDRPTLASFSPTTKTKTLLEPQSPQSPAGACKKKPSFPEVRTSKKENQAAGSLVPGRENSTGLAKESPVESPISRTGCQFEPGVTNLKLREFSEVRQLKSPESTLPRCKERITGIACVLDNQPGLCPLDPIRPRSPTSVTALAQVSESSISVEQCEHVVSELQDSMRKAIHLYRAVLNDTESSTDKDKIAGLLTETFSLMKKELDSLKDEEELPKVKEVLTKPQDTARSLNDKCGANLPSPKSLGDEQTLALLEQYSELLLQAVERRMDKKL", "length": 1632, "header": "tr|A0A8V0ZJR8-1|A0A8V0ZJR8_CHICK Computationally mapped isoform of WD repeat domain 62 OS=Gallus gallus OX=9031 GN=WDR62 PE=4 SV=1 CANONICAL=A0A8V0ZDR0-1" }, "locus": { "chromosome": "5", "start_pos": 24651642, "end_pos": 24562793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048798.1", "url": "https://www.ensembl.org/id/ENSGALT00010048798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028848.1", "url": "https://www.ensembl.org/id/ENSGALP00010028848.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771487", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "negative regulation of interleukin-8 production", "id": "GO:0032717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032717", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" }, { "name": "negative regulation of defense response to bacterium", "id": "GO:1900425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1090, "end_pos": 1092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1425, "end_pos": 1427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1544, "end_pos": 1546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 926, "end_pos": 928, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" }, { "id": "PF24780", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24780" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP1/WDR62 first WD40", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 387, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" }, { "id": "PF24782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP1/WDR62 second WD40", "eco_id": "ECO_0000259", "start_pos": 393, "end_pos": 736, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZDR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDR0" }, { "id": "PF24795", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24795" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP1/WRD62 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 1516, "end_pos": 1632, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1090, "end_pos": 1092 }, { "start_pos": 1137, "end_pos": 1139 }, { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1425, "end_pos": 1427 }, { "start_pos": 1544, "end_pos": 1546 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 926, "end_pos": 928 }, { "start_pos": 986, "end_pos": 988 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZDS6", "locus": { "chromosome": "9", "start_pos": 18909686, "end_pos": 18847899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018507", "url": "https://www.ensembl.org/id/ENSGALG00010018507" } ] } } ], "crossref": [ { "id": "A0A8V0ZDS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDS6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47228:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47228:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGQNEASQQTQASKESSVAANKLNDIPETLEEVKNHLGDGAVRNITERIKEAETKEEKQSNDVGRASPKWESENNEKQNGEKEATKLRSGNPLTLAPLSHIPLNTVMHVEMELVYADEQEIAFEFAVPAALHGRADATSAATSSAVPRVDERLWAALQEASRHYRQKNYAVAAGRFATALELCSKGAAIDKSSKPFPEDISSIASFIEMKLVTCYLKLRKPDLALNHSHRSIILNPAYFRNHLCQAAVFRWLERYSEAARSAMIADYMYWLTGGTEQRISKLIKLYWQAMIEEAITREESFSVMYTPFVTKVKVDNRDKMTDAFTKMHPGYTQHIFTDPHGLHILPQTTEWSSSPPQQYLLTLGFRNKQIGKILEKLPSRKLPIFSDCKAPFSPIPEDELRRQWETIGKQIMPVMDFMRSTRLTDDVCACSRAIEKLHYASILGRLQQVTEQSQVINQAMAELASIPYLQDISQQDTELLQSLMADAMDTLEGRRSDKERVWNEIEKVKTCSKGQRSILFLGDCGRTKFIRTNEVPEWSTNEALVMRDRTAM", "length": 553, "header": "tr|A0A8V0ZDS6-1|A0A8V0ZDS6_CHICK Isoform 1 of Spermatogenesis-associated protein 16 OS=Gallus gallus OX=9031 GN=SPATA16 PE=3 SV=1 CANONICAL=A0A8V0ZDS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6/entry#A0A8V0ZDS6-1", "sequence": { "sequence": "MYGQNEASQQTQASKESSVAANKLNDIPETLEEVKNHLGDGAVRNITERIKEAETKEEKQSNDVGRASPKWESENNEKQNGEKEATKLRSGNPLTLAPLSHIPLNTVMHVEMELVYADEQEIAFEFAVPAALHGRADATSAATSSAVPRVDERLWAALQEASRHYRQKNYAVAAGRFATALELCSKGAAIDKSSKPFPEDISSIASFIEMKLVTCYLKLRKPDLALNHSHRSIILNPAYFRNHLCQAAVFRWLERYSEAARSAMIADYMYWLTGGTEQRISKLIKLYWQAMIEEAITREESFSVMYTPFVTKVKVDNRDKMTDAFTKMHPGYTQHIFTDPHGLHILPQTTEWSSSPPQQYLLTLGFRNKQIGKILEKLPSRKLPIFSDCKAPFSPIPEDELRRQWETIGKQIMPVMDFMRSTRLTDDVCACSRAIEKLHYASILGRLQQVTEQSQVINQAMAELASIPYLQDISQQDTELLQSLMADAMDTLEGRRSDKERVWNEIEKVKTCSKGQRSILFLGDCGRTKFIRTNEVPEWSTNEALVMRDRTAM", "length": 553, "header": "tr|A0A8V0ZDS6-1|A0A8V0ZDS6_CHICK Isoform 1 of Spermatogenesis-associated protein 16 OS=Gallus gallus OX=9031 GN=SPATA16 PE=3 SV=1 CANONICAL=A0A8V0ZDS6-1" }, "locus": { "chromosome": "9", "start_pos": 18909683, "end_pos": 18847899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044778.1", "url": "https://www.ensembl.org/id/ENSGALT00010044778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026700.1", "url": "https://www.ensembl.org/id/ENSGALP00010026700.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDV0-1", "uniprot_ac": "A0A8V0ZDV0", "uniprot_id": "A0A8V0ZDV0_CHICK", "mass": { "chemical_mass": 97436.0, "monoisotopic_mass": 97436.0 }, "refseq": {}, "gene_names": [ { "name": "MTTPL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ] } ], "protein_names": [ { "name": "Microsomal triglyceride transfer protein-like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTTPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0", "locus": { "chromosome": "6", "start_pos": 12285073, "end_pos": 12294194, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020327", "url": "https://www.ensembl.org/id/ENSGALG00010020327" } ] } } ], "crossref": [ { "id": "A0A8V0ZDV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZDV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE81", "url": "https://www.orthodb.org/?gene=A0A8V0ZE81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK94", "url": "https://www.orthodb.org/?gene=A0A8V0ZK94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13024:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13024:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19444", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19444", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQWALWGYICLLCCSFLSTAKGSPWVLSFQPGMLYQYHYALAMQLGPVAGLSPSGGWLQAQAVVRIRQLHRDPSGDELLQVQIQDLKAQQKPEGPEGPPMDIALNEEVQSELQKPVFISWSSGKIKALHGDETEGTLITNLKRGVVSLLQLQPHASTIVEEDASGSCQVTYTVSNHSIVKTKDLLSCTKPKMGYASPNKMFGIQWQPSSRSLYVVKDSLLQSVLAEESHMLSLVLRSTTGVKIKIKLFSSWRPHQTPLDSSQPGVKDESLENVLASIEGQHQPLAIASLPFRRGCTHCPSLTAYLKTFDSQQAKMDISKAATTWQFQRFIQMLRSAKKRDVLQLLKRAPEKMLPFVVEAAVAAQSVPALAALSDFLDFSKEPGSLLETFLYAAAFSPRPTKELLRLVLDKLDGKQMAPEVRDTGMVALGSLVGKLCQQQLCGLQEVKHGMETILTGLRSAEKEHEAVIHLLALGNAQLPSTIPTLLEHAEKGPTAVAAAAISALRQFRAWHITSEVKRAMRRIFHEKRKSYEKTCRLAAAEILLDNTPLSMDVINILLAAHHLGTEAATFLLLKVQSSLHANHHPARKIMSDIMRDPRINNYNHFSKAGISSSFSGPLTATKELLSTFGLDLLFLEGGFLRKSVSDFSLLSQDWHLRAAQVTIEAQGMESMLGENTLEGEEGPELTAGMSAIFFDVQLRPIIFFKGYTDLMAKVLLSSGEPTSVVKGNLLLMDHHQVIPLQSGLQAVVKLQGGLGLDISANVDVNIWEQELKTSVDTRGSLTIDFQAELDTPFLHTTLRSQTEAETSIYFDTILRFSSSPVLMCLQLREDQVPYREVFTISTSAGNQSSTIRKGRQGTVPAQEFALHQANSEMCHLLLTAEEGA", "length": 885, "header": "tr|A0A8V0ZDV0-1|A0A8V0ZDV0_CHICK Isoform 1 of Microsomal triglyceride transfer protein-like OS=Gallus gallus OX=9031 GN=MTTPL PE=1 SV=1 CANONICAL=A0A8V0ZDV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0/entry#A0A8V0ZDV0-1", "sequence": { "sequence": "MGQWALWGYICLLCCSFLSTAKGSPWVLSFQPGMLYQYHYALAMQLGPVAGLSPSGGWLQAQAVVRIRQLHRDPSGDELLQVQIQDLKAQQKPEGPEGPPMDIALNEEVQSELQKPVFISWSSGKIKALHGDETEGTLITNLKRGVVSLLQLQPHASTIVEEDASGSCQVTYTVSNHSIVKTKDLLSCTKPKMGYASPNKMFGIQWQPSSRSLYVVKDSLLQSVLAEESHMLSLVLRSTTGVKIKIKLFSSWRPHQTPLDSSQPGVKDESLENVLASIEGQHQPLAIASLPFRRGCTHCPSLTAYLKTFDSQQAKMDISKAATTWQFQRFIQMLRSAKKRDVLQLLKRAPEKMLPFVVEAAVAAQSVPALAALSDFLDFSKEPGSLLETFLYAAAFSPRPTKELLRLVLDKLDGKQMAPEVRDTGMVALGSLVGKLCQQQLCGLQEVKHGMETILTGLRSAEKEHEAVIHLLALGNAQLPSTIPTLLEHAEKGPTAVAAAAISALRQFRAWHITSEVKRAMRRIFHEKRKSYEKTCRLAAAEILLDNTPLSMDVINILLAAHHLGTEAATFLLLKVQSSLHANHHPARKIMSDIMRDPRINNYNHFSKAGISSSFSGPLTATKELLSTFGLDLLFLEGGFLRKSVSDFSLLSQDWHLRAAQVTIEAQGMESMLGENTLEGEEGPELTAGMSAIFFDVQLRPIIFFKGYTDLMAKVLLSSGEPTSVVKGNLLLMDHHQVIPLQSGLQAVVKLQGGLGLDISANVDVNIWEQELKTSVDTRGSLTIDFQAELDTPFLHTTLRSQTEAETSIYFDTILRFSSSPVLMCLQLREDQVPYREVFTISTSAGNQSSTIRKGRQGTVPAQEFALHQANSEMCHLLLTAEEGA", "length": 885, "header": "tr|A0A8V0ZDV0-1|A0A8V0ZDV0_CHICK Isoform 1 of Microsomal triglyceride transfer protein-like OS=Gallus gallus OX=9031 GN=MTTPL PE=1 SV=1 CANONICAL=A0A8V0ZDV0-1" }, "locus": { "chromosome": "6", "start_pos": 12294110, "end_pos": 12285587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049092.1", "url": "https://www.ensembl.org/id/ENSGALT00010049092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029028.1", "url": "https://www.ensembl.org/id/ENSGALP00010029028.1" } ] } }, { "isoform_ac": "A0A8V0ZE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0/entry#A0A8V0ZE81-1", "sequence": { "sequence": "MGQWALWGYICLLCCSFLSTAKGSPWVLSFQPGMLYQYHYALAMQLGPVAGLSPSGGWLQAQAVVRIRQLHRDPSGDELLQVQIQDLKAQQKPEGPEGPPMDIALNEEVQSELQKPVFISWSSGKIKALHGDETEGTLITNLKRGVVSLLQLQPHASTIVEEDASGSCQVTYTVSNHSIVKTKDLLSCTKPKMGYASPNKMFGIQWQPSSRSLYVVKDSLLQSVLAEESHMLSLVLRSTTGVKISSRQELKLVSSTPSPAVAAEESLENVLASIEGQHQPLAIASLPFRRGCTHCPSLTAYLKTFDSQQAKMDISKAATTWQFQRFIQMLRSAKKRDVLQLLKRAPEKMLPFVVEAAVAAQSVPALAALSDFLDFSKEPGSLLETFLYAAAFSPRPTKELLRLVLDKLDGKQMAPEVRDTGMVALGSLVGKLCQQQLCGLQEVKHGMETILTGLRSAEKEHEAVIHLLALGNAQLPSTIPTLLEHAEKGPTAVAAAAISALRQFRAWHITSEVKRAMRRIFHEKRKSYEKTCRLAAAEILLDNTPLSMDVINILLAAHHLGTEAATFLLLKVQSSLHANHHPARKIMSDIMRDPRINNYNHFSKAGISSSFSGPLTATKELLSTFGLDLLFLEGGFLRKSVSDFSLLSQDWHLRAAQVTIEAQGMESMLGENTLEGEEGPELTAGMSAIFFDVQLRPIIFFKGYTDLMAKVLLSSGEPTSVVKGNLLLMDHHQVIPLQSGLQAVVKLQGGLGLDISANVDVNIWEQELKTSVDTREVFTISTSAGNQSSTIRKGRQGTVPAQEFALHQANSEMCHLLLTAEEGA", "length": 824, "header": "tr|A0A8V0ZE81-1|A0A8V0ZE81_CHICK Computationally mapped isoform of Microsomal triglyceride transfer protein-like OS=Gallus gallus OX=9031 GN=MTTPL PE=1 SV=1 CANONICAL=A0A8V0ZDV0-1" }, "locus": { "chromosome": "6", "start_pos": 12294110, "end_pos": 12285587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049083.1", "url": "https://www.ensembl.org/id/ENSGALT00010049083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029022.1", "url": "https://www.ensembl.org/id/ENSGALP00010029022.1" } ] } }, { "isoform_ac": "A0A8V0ZK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0/entry#A0A8V0ZK94-1", "sequence": { "sequence": "MGQWALWGYICLLCCSFLSTAKGSPWVLSFQPGMLYQYHYALAMQLGPVAGLSPSGGWLQAQAVVRIRQLHRDPSGDELLQVQIQDLKAQQKPEGPEGPPMDIALNEEVQSELQKPVFISWSSGKIKALHGDETEGTLITNLKRGVVSLLQLQPHASTIVEEDASGSCQVTYTVSNHSIVKTKDLLSCTKPKMGYASPNKMFGIQWQPSSRSLYVVKDSLLQSVLAEESHMLSLVLRSTTGVKISSRQELKLVSSTPSPAVAAEESLENVLASIEGQHQPLAIASLPFRRGCTHCPSLTAYLKTFDSQQAKMDISKAATTWQFQRFIQMLRSAKKRDVLQLLKRAPEKMLPFVVEAAVAAQSVPALAALSDFLDFSKEPGSLLETFLYAAAFSPRPTKELLRLVLDKLDGKQMAPEVRDTGMVALGSLVGKLCQQQLCGLQEVKHGMETILTGLRSAEKEHEAVIHLLALGNAQLPSTIPTLLEHAEKGPTAVAAAAISALRQFRAWHITSEVKRAMRRIFHEKRKSYEKTCRLAAAEILLDNTPLSMDVINILLAAHHLGTEAATFLLLKVQSSLHANHHPARKIMSDIMRDPRINNYNHFSKAGISSSFSGPLTATKELLSTFGLDLLFLEGGFLRKSVSDFSLLSQDWHLRAAQLRPIIFFKGYTDLMAKVLLSSGEPTSVVKGNLLLMDHHQVIPLQSGLQAVVKLQGGLGLDISANVDVNIWEQELKTSVDTRGSLTIDFQAELDTPFLHTTLRSQTEAETSIYFDTILRFSSSPVLMCLQLREDQVPYRHCSNSSSCFSWTLLKHHSL", "length": 814, "header": "tr|A0A8V0ZK94-1|A0A8V0ZK94_CHICK Computationally mapped isoform of Microsomal triglyceride transfer protein-like OS=Gallus gallus OX=9031 GN=MTTPL PE=1 SV=1 CANONICAL=A0A8V0ZDV0-1" }, "locus": { "chromosome": "6", "start_pos": 12294110, "end_pos": 12286495, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049079.1", "url": "https://www.ensembl.org/id/ENSGALT00010049079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029020.1", "url": "https://www.ensembl.org/id/ENSGALP00010029020.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipoprotein metabolic process", "id": "GO:0042157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV0" }, { "id": "PS51211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vitellogenin", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 645, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 847, "end_pos": 849 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDV9-1", "uniprot_ac": "A0A8V0ZDV9", "uniprot_id": "A0A8V0ZDV9_CHICK", "mass": { "chemical_mass": 68011.0, "monoisotopic_mass": 68011.0 }, "refseq": { "ac": "XP_417571", "name": "Golgi integral membrane protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417571" }, "gene_names": [ { "name": "LOC419409", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9" } ] }, { "name": "LOC419409", "type": "synonym", "evidence": [ { "id": "XP_417571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417571" } ] } ], "protein_names": [ { "name": "Golgi integral membrane protein 4-like", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9/entry#names_and_taxonomy" } ] }, { "name": "Golgi integral membrane protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417571" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417571.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417571" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC419409", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZDV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "419409", "url": "https://www.ncbi.nlm.nih.gov/gene/419409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LQMDAGM", "url": "https://omabrowser.org/oma/group/LQMDAGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDV9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22909:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22909:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_417571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTGMCSRRQKGLLQTGFCLLAVACLGSGAFLYHHLQQKVRSAEALAQKYKQQQEALSAQLQVVYEHRSRLERSLQKERGEHKKTKEDFLVYKLEAQEALNKEKQDSMNRYGALSSQHKILKNQHEDVKKQLIDLQLQHNSLKLEHRKTLETHSQKYAQLQQEKDSEVTNLQDTVFKLREESKLLRKAHQEVHSQLLNAQTQMEEFRQLKEALQKMPSFKGGGGGKGQQQLQVLKEQQPLDPGNSQLQLTRQKAFPVNPENRPAGSSLASHVSGVRKQADSPVLRGQSSNSNDGLRSQVNMLLTHPAPLQDANSPPEAPPAWPAGRGDGHIIRFTRTVNSLPNGNPDVNMVMRIQVSSHEESQAPGLLLSDLKQPSAAEKTQMPDNHHSTGSKPVQMQSWKDIVSKVNAQMDDAQVHSYPKSPHLNPRPGQETQKGSSQPSSQKRGAENQIGDQEDEKERTDNEELEMDAGMIERENLHSQKESVVQEPMMPDDAADPAQDPNNQGEDEFEEAELERPDFEEKVGGLEKFKEPGAKEASKEKPLKDAGRPVKPREDPMDDYQEDQEQEIEDHGGEVDDNDDLELVQEQKNHAGIQGADGKKDDYY", "length": 605, "header": "tr|A0A8V0ZDV9-1|A0A8V0ZDV9_CHICK Isoform 1 of Golgi integral membrane protein 4-like OS=Gallus gallus OX=9031 GN=LOC419409 PE=4 SV=1 CANONICAL=A0A8V0ZDV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9/entry#A0A8V0ZDV9-1", "sequence": { "sequence": "MGTGMCSRRQKGLLQTGFCLLAVACLGSGAFLYHHLQQKVRSAEALAQKYKQQQEALSAQLQVVYEHRSRLERSLQKERGEHKKTKEDFLVYKLEAQEALNKEKQDSMNRYGALSSQHKILKNQHEDVKKQLIDLQLQHNSLKLEHRKTLETHSQKYAQLQQEKDSEVTNLQDTVFKLREESKLLRKAHQEVHSQLLNAQTQMEEFRQLKEALQKMPSFKGGGGGKGQQQLQVLKEQQPLDPGNSQLQLTRQKAFPVNPENRPAGSSLASHVSGVRKQADSPVLRGQSSNSNDGLRSQVNMLLTHPAPLQDANSPPEAPPAWPAGRGDGHIIRFTRTVNSLPNGNPDVNMVMRIQVSSHEESQAPGLLLSDLKQPSAAEKTQMPDNHHSTGSKPVQMQSWKDIVSKVNAQMDDAQVHSYPKSPHLNPRPGQETQKGSSQPSSQKRGAENQIGDQEDEKERTDNEELEMDAGMIERENLHSQKESVVQEPMMPDDAADPAQDPNNQGEDEFEEAELERPDFEEKVGGLEKFKEPGAKEASKEKPLKDAGRPVKPREDPMDDYQEDQEQEIEDHGGEVDDNDDLELVQEQKNHAGIQGADGKKDDYY", "length": 605, "header": "tr|A0A8V0ZDV9-1|A0A8V0ZDV9_CHICK Isoform 1 of Golgi integral membrane protein 4-like OS=Gallus gallus OX=9031 GN=LOC419409 PE=4 SV=1 CANONICAL=A0A8V0ZDV9-1" }, "locus": { "chromosome": "21", "start_pos": 2101782, "end_pos": 2079822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048886.1", "url": "https://www.ensembl.org/id/ENSGALT00010048886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028895.1", "url": "https://www.ensembl.org/id/ENSGALP00010028895.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDX1-1", "uniprot_ac": "A0A8V0ZDX1", "uniprot_id": "A0A8V0ZDX1_CHICK", "mass": { "chemical_mass": 36691.0, "monoisotopic_mass": 36691.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "SUN domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZDX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ASCVFRFKLTLREWLDLSCCGDLWAIPALCLTRAPSPGQESVLSVLRVCRGASQQETSLPAASVSGAPEGAASPFPCQIVTGELWRFPGNSSVPYIQVEQPSLLWLALQGSWEATLFPVLFLLTSTLLCLSSQAVQKIIHQVLEKLEESPFQMTNYASKTSGATIIRSKTSPSWIGSGRVFWQSLPLMAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAIFPMAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKRTLLGEFTFMPGQAPGQTFQLKNEHSGFIKYVRLQVLSNWGHPDYTCLYQFRLHGDPAHDGDARGKLSA", "length": 334, "header": "tr|A0A8V0ZDX1-1|A0A8V0ZDX1_CHICK Isoform 1 of SUN domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1/entry#A0A8V0ZDX1-1", "sequence": { "sequence": "ASCVFRFKLTLREWLDLSCCGDLWAIPALCLTRAPSPGQESVLSVLRVCRGASQQETSLPAASVSGAPEGAASPFPCQIVTGELWRFPGNSSVPYIQVEQPSLLWLALQGSWEATLFPVLFLLTSTLLCLSSQAVQKIIHQVLEKLEESPFQMTNYASKTSGATIIRSKTSPSWIGSGRVFWQSLPLMAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAIFPMAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKRTLLGEFTFMPGQAPGQTFQLKNEHSGFIKYVRLQVLSNWGHPDYTCLYQFRLHGDPAHDGDARGKLSA", "length": 334, "header": "tr|A0A8V0ZDX1-1|A0A8V0ZDX1_CHICK Isoform 1 of SUN domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDX1-1" }, "locus": { "chromosome": "2", "start_pos": 41687699, "end_pos": 41684714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044828.1", "url": "https://www.ensembl.org/id/ENSGALT00010044828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026750.1", "url": "https://www.ensembl.org/id/ENSGALP00010026750.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZDX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX1" }, { "id": "PS51469", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUN", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 323, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDX3-1", "uniprot_ac": "A0A8V0ZDX3", "uniprot_id": "A0A8V0ZDX3_CHICK", "mass": { "chemical_mass": 111737.0, "monoisotopic_mass": 111737.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGAP11B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 11B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP11B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3", "locus": { "chromosome": "5", "start_pos": 30111234, "end_pos": 30140529, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021647", "url": "https://www.ensembl.org/id/ENSGALG00010021647" } ] } } ], "crossref": [ { "id": "A0A8V0ZDX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL17", "url": "https://www.orthodb.org/?gene=A0A8V0ZL17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15670", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15670", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15670:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15670:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQRRGLLRLAVLQELRVSYGIKVKSGACLAAAKQPAAAAAAEGKIFGTSFYALPQSLVPEYGYIPSFLVDACEYLEEHVQTEGLFRKSGSLVRLKALKSKLDQGENCLSAALPCDVAGLLKQFFRELPEPILPSHLQDGLLKAQQLANGKKAATMLLSCLMTDRTIETLRYFFNFLRTVSSRSNENRMDSGNLAVIFAPNLLHSNENEKLSTSTEKKIRLQAAVVQTFIDHAEEIGQVPEFILEKIPAMLGVDPFQSTPSLRGYEDSENESPSECKRRRHRSVGDFVSGALNKFKSNRTPSTTPQQDRSVLSSVTPVVLTPSTKRKLPADCSQGLSSKKRRSFKHGFGFELLPSSIFNSSSTPASVQFEASPCVSLESPQTSLSPSTCGENHLSSTGNRRSKRFASKKLYRAESGKTGCFSPKISRKEMVRRSLRLKFGLGKSSRDVNVASGCAVGNRAENIGRRLASQQSLESGAECAKRGVLFSPCINEKVCKKGSKNVSKSEENLLTPKCRNKAVYRMSWNSPTVTDSQEISSNEGILPENSSSESAFLFEKPPVLPDECRLTAEEQQDSRLKLCEEANNLTAETLLKVKQAFSVSGSNLHNLRADTKSSFSGVTDETLKETPCLTGLSPEKELVAGASCSPAKVESRELFHQQCQSYATDKQQPKKDEIKTLEKKSFRTSIEIELQIQKPDIRNVIELPVTQVLAREDNLTVQNSSSKDDLKNLDSFGRKEEVELTHSQTAENGTVHCCNSDEGTAKLPGAGQLPALQLPVSGNEVGNQYLQGENSAKTLTKASTFPDHGKVSDHIQWFNKLSLNDPSSASKTKPPLKFQRTPVRQSVRRMNSLLEANKRSISFQLGIANNVGSPLVKSLSCDSALSSCTEKPNKNSSALSLRSESTFDQVSTSHSQLDLASKPRCRHLYLSDKSDGSVRTTGIYRQKVTVQPSKNVLEDLTNQETVKSCLKVNADINISDFAPEKSTITRSASGKEKARYRGSPKNPISKVKLLPTAKPVDL", "length": 1019, "header": "tr|A0A8V0ZDX3-1|A0A8V0ZDX3_CHICK Isoform 1 of Rho GTPase activating protein 11B OS=Gallus gallus OX=9031 GN=ARHGAP11B PE=4 SV=1 CANONICAL=A0A8V0ZDX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3/entry#A0A8V0ZDX3-1", "sequence": { "sequence": "MAEQRRGLLRLAVLQELRVSYGIKVKSGACLAAAKQPAAAAAAEGKIFGTSFYALPQSLVPEYGYIPSFLVDACEYLEEHVQTEGLFRKSGSLVRLKALKSKLDQGENCLSAALPCDVAGLLKQFFRELPEPILPSHLQDGLLKAQQLANGKKAATMLLSCLMTDRTIETLRYFFNFLRTVSSRSNENRMDSGNLAVIFAPNLLHSNENEKLSTSTEKKIRLQAAVVQTFIDHAEEIGQVPEFILEKIPAMLGVDPFQSTPSLRGYEDSENESPSECKRRRHRSVGDFVSGALNKFKSNRTPSTTPQQDRSVLSSVTPVVLTPSTKRKLPADCSQGLSSKKRRSFKHGFGFELLPSSIFNSSSTPASVQFEASPCVSLESPQTSLSPSTCGENHLSSTGNRRSKRFASKKLYRAESGKTGCFSPKISRKEMVRRSLRLKFGLGKSSRDVNVASGCAVGNRAENIGRRLASQQSLESGAECAKRGVLFSPCINEKVCKKGSKNVSKSEENLLTPKCRNKAVYRMSWNSPTVTDSQEISSNEGILPENSSSESAFLFEKPPVLPDECRLTAEEQQDSRLKLCEEANNLTAETLLKVKQAFSVSGSNLHNLRADTKSSFSGVTDETLKETPCLTGLSPEKELVAGASCSPAKVESRELFHQQCQSYATDKQQPKKDEIKTLEKKSFRTSIEIELQIQKPDIRNVIELPVTQVLAREDNLTVQNSSSKDDLKNLDSFGRKEEVELTHSQTAENGTVHCCNSDEGTAKLPGAGQLPALQLPVSGNEVGNQYLQGENSAKTLTKASTFPDHGKVSDHIQWFNKLSLNDPSSASKTKPPLKFQRTPVRQSVRRMNSLLEANKRSISFQLGIANNVGSPLVKSLSCDSALSSCTEKPNKNSSALSLRSESTFDQVSTSHSQLDLASKPRCRHLYLSDKSDGSVRTTGIYRQKVTVQPSKNVLEDLTNQETVKSCLKVNADINISDFAPEKSTITRSASGKEKARYRGSPKNPISKVKLLPTAKPVDL", "length": 1019, "header": "tr|A0A8V0ZDX3-1|A0A8V0ZDX3_CHICK Isoform 1 of Rho GTPase activating protein 11B OS=Gallus gallus OX=9031 GN=ARHGAP11B PE=4 SV=1 CANONICAL=A0A8V0ZDX3-1" }, "locus": { "chromosome": "5", "start_pos": 30122737, "end_pos": 30112115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052583.1", "url": "https://www.ensembl.org/id/ENSGALT00010052583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031489.1", "url": "https://www.ensembl.org/id/ENSGALP00010031489.1" } ] } }, { "isoform_ac": "A0A8V0ZL17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDX3/entry#A0A8V0ZL17-1", "sequence": { "sequence": "MAYVSTGTVHSLILLFHLLHLEKGKIFGTSFYALPQSLVPEYGYIPSFLVDACEYLEEHVQTEGLFRKSGSLVRLKALKSKLDQGENCLSAALPCDVAGLLKQFFRELPEPILPSHLQDGLLKAQQLANGKKAATMLLSCLMTDRTIETLRYFFNFLRTVSSRSNENRMDSGNLAVIFAPNLLHSNENEKLSTSTEKKIRLQAAVVQTFIDHAEEIGQVPEFILEKIPAMLGVDPFQSTPSLRGYEDSENESPSECKRRRHRSVGVLSSVTPVVLTPSTKRKLPADCSQGLSSKKRRSFKHGFGFELLPSSIFNSSSTPASVQFEASPCVSLESPQTSLSPSTCGENHLSSTGNRRSKRFASKKLYRAESGKTGCFSPKISRKEMVRRSLRLKFGLGKSSRDVNVASGCAVGNRAENIGRRLASQQSLESGAECAKRGVLFSPCINEKVCKKGSKNVSKSEENLLTPKCRNKAVYRMSWNSPTVTDSQEISSNEGILPENSSSESAFLFEKPPVLPDECRLTAEEQQDSRLKLCEEANNLTAETLLKVKQAFSVSGSNLHNLRADTKSSFSGVTDETLKETPCLTGLSPEKELVAGASCSPAKVESRELFHQQCQSYATDKQQPKKDEIKTLEKKSFRTSIEIELQIQKPDIRNVIELPVTQVLAREDNLTVQNSSSKDDLKNLDSFGRKEEVELTHSQTAENGTVHCCNSDEGTAKLPGAGQLPALQLPVSGNEVGNQYLQGENSAKTLTKASTFPDHGKVSDHIQWFNKLSLNDPSSASKTKPPLKFQRTPVRQSVRRMNSLLEANKRSISFQLGIANNVGSPLVKSLSCDSALSSCTEKPNKNSSALSLRSESTFDQVSTSHSQLDLASKPRCRHLYLSDKSDGSVRTTGIYRQKVTVQPSKNVLEDLTNQETVKSCLKVNADINISDFAPEKSTITRSASGKEKARYRGSPKNPISKVKLLPTAKPVDL", "length": 973, "header": "tr|A0A8V0ZL17-1|A0A8V0ZL17_CHICK Computationally mapped isoform of Rho GTPase activating protein 11B OS=Gallus gallus OX=9031 GN=ARHGAP11B PE=4 SV=1 CANONICAL=A0A8V0ZDX3-1" }, "locus": { "chromosome": "5", "start_pos": 30140291, "end_pos": 30112115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052587.1", "url": "https://www.ensembl.org/id/ENSGALT00010052587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031493.1", "url": "https://www.ensembl.org/id/ENSGALP00010031493.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025000826.1. 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDZ2-1", "uniprot_ac": "A0A8V0ZDZ2", "uniprot_id": "A0A8V0ZDZ2_CHICK", "mass": { "chemical_mass": 47555.0, "monoisotopic_mass": 47555.0 }, "refseq": { "ac": "XP_024998321", "name": "5-hydroxytryptamine receptor 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998321" }, "gene_names": [ { "name": "HTR6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ] }, { "name": "HTR6", "type": "synonym", "evidence": [ { "id": "XP_024998321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998321" } ] } ], "protein_names": [ { "name": "5-hydroxytryptamine receptor 6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZDZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2/entry#names_and_taxonomy" } ] }, { "name": "5-hydroxytryptamine receptor 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024998321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998321" } ] }, { "name": "Serotonin receptor 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024998321.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998321" } ] }, { "annotation": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Also has a high affinity for tricyclic psychotropic drugs. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR6 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity. Is an activator of mTOR signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2#function" }, { "database": "UniProtKB", "id": "ARBA00059774", "url": "https://www.uniprot.org/uniprotkb/ARBA00059774#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HTR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2", "locus": { "chromosome": "21", "start_pos": 4777689, "end_pos": 4774163, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020643", "url": "https://www.ensembl.org/id/ENSGALG00010020643" } ] } } ], "crossref": [ { "id": "A0A8V0ZDZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430019", "url": "https://www.ncbi.nlm.nih.gov/gene/430019", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KMGWHEL", "url": "https://omabrowser.org/oma/group/KMGWHEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390666", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390666", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024998321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGNLGSPNASVLGERSLLVGSSWVAAFLCFIILLTTAGNFLLILLIVTQRSLRNTSNYFLVSLFMSDLMVGLVVMPPAMLNQLYGHWVLRGDFCSLWYAFDVMCCSASILNLCVISLDRYLLIISPLKYKLRMTSCRALWLILATWTLAALASFLPIKLGWHKLEFEVWSPNVTSRGDEEQCRLVVSLPYALVASCLTFFLPSAAISFTYCRILLAARKQAVQVASLASNVATATTDESVEQVPHAPSQPAAGSESRRFANKHSKKALKASLTLGILLGMFFVAWLPFFVTNVTQAVCDCVPAGFFDVLTWLGYCNSTMNPIIYPLFMRDFKRAMGKYLPCCRRTGEPRPSAISLSMKNSNSGPRAATSLKNVLTLQAETDSVVSEVVANEHRLLPAAEGALPAPSAHLVGLFEMETSELELQRRQLGTPVA", "length": 433, "header": "tr|A0A8V0ZDZ2-1|A0A8V0ZDZ2_CHICK Isoform 1 of 5-hydroxytryptamine receptor 6 OS=Gallus gallus OX=9031 GN=HTR6 PE=3 SV=1 CANONICAL=A0A8V0ZDZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2/entry#A0A8V0ZDZ2-1", "sequence": { "sequence": "MEGNLGSPNASVLGERSLLVGSSWVAAFLCFIILLTTAGNFLLILLIVTQRSLRNTSNYFLVSLFMSDLMVGLVVMPPAMLNQLYGHWVLRGDFCSLWYAFDVMCCSASILNLCVISLDRYLLIISPLKYKLRMTSCRALWLILATWTLAALASFLPIKLGWHKLEFEVWSPNVTSRGDEEQCRLVVSLPYALVASCLTFFLPSAAISFTYCRILLAARKQAVQVASLASNVATATTDESVEQVPHAPSQPAAGSESRRFANKHSKKALKASLTLGILLGMFFVAWLPFFVTNVTQAVCDCVPAGFFDVLTWLGYCNSTMNPIIYPLFMRDFKRAMGKYLPCCRRTGEPRPSAISLSMKNSNSGPRAATSLKNVLTLQAETDSVVSEVVANEHRLLPAAEGALPAPSAHLVGLFEMETSELELQRRQLGTPVA", "length": 433, "header": "tr|A0A8V0ZDZ2-1|A0A8V0ZDZ2_CHICK Isoform 1 of 5-hydroxytryptamine receptor 6 OS=Gallus gallus OX=9031 GN=HTR6 PE=3 SV=1 CANONICAL=A0A8V0ZDZ2-1" }, "locus": { "chromosome": "21", "start_pos": 4777644, "end_pos": 4774164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049832.1", "url": "https://www.ensembl.org/id/ENSGALT00010049832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029439.1", "url": "https://www.ensembl.org/id/ENSGALP00010029439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-390666", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390666", "resource": "Reactome", "description": "Serotonin receptors" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BE22-1", "protein_name": "5-hydroxytryptamine receptor 6", "gene_name": "HTR6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVPEQGPANYSTPDWGSGPPWAPGGSGWVAAALCVVIALTAAANSLLIALICAQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNVLYGRWVLARGLCLLWAAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPARALALVLGAWSLAALASFLPLLLGWHEPGRARAPAPGQCRLLASLPFVLVASGLTFFLPSGAICFTYSRILLAARKQAIQVASLTTGTAGQALETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISLGLFDTLTWLGYCNSTMNPIIYPLFMRDFKRALGRLLPCPRGPREQQPGLASPSVRTSHSGARPGLSLQHVLPLPLPPDSDSDSGSGSGGFSGPRLTAQLLLPGEATRDPPPPARATTTVNFFSIDRAEPELRPRPPGTPTN", "length": 440 }, "evidence": [ { "id": "A0A8V0ZDZ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P31388-1", "protein_name": "5-hydroxytryptamine receptor 6", "gene_name": "Htr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVPRTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVPDQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLSQTLWSLRYGRIHSVPP", "length": 436 }, "evidence": [ { "id": "A0A8V0ZDZ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50406-1", "protein_name": "5-hydroxytryptamine receptor 6", "gene_name": "HTR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN", "length": 440 }, "evidence": [ { "id": "A0A8V0ZDZ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZDZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1C8-1", "protein_name": "5-hydroxytryptamine receptor 6", "gene_name": "Htr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled serotonin receptor activity", "id": "GO:0004993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" }, { "name": "neurotransmitter receptor activity", "id": "GO:0030594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ2" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZDZ8-1", "uniprot_ac": "A0A8V0ZDZ8", "uniprot_id": "A0A8V0ZDZ8_CHICK", "mass": { "chemical_mass": 8802.0, "monoisotopic_mass": 8802.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZDZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZDZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZDZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZDZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RCYQLCLVPTSIWEPLLGQCEETLLAFKSDAYIVQATKSGEGKSMPLTCTSRYQFYTLRLIHTCFNGYSKKGSCPTHS", "length": 78, "header": "tr|A0A8V0ZDZ8-1|A0A8V0ZDZ8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ8/entry#A0A8V0ZDZ8-1", "sequence": { "sequence": "RCYQLCLVPTSIWEPLLGQCEETLLAFKSDAYIVQATKSGEGKSMPLTCTSRYQFYTLRLIHTCFNGYSKKGSCPTHS", "length": 78, "header": "tr|A0A8V0ZDZ8-1|A0A8V0ZDZ8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZDZ8-1" }, "locus": { "chromosome": "12", "start_pos": 17074798, "end_pos": 17073794, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049177.1", "url": "https://www.ensembl.org/id/ENSGALT00010049177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029074.1", "url": "https://www.ensembl.org/id/ENSGALP00010029074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE18-1", "uniprot_ac": "A0A8V0ZE18", "uniprot_id": "A0A8V0ZE18_CHICK", "mass": { "chemical_mass": 101685.0, "monoisotopic_mass": 101685.0 }, "refseq": { "ac": "XP_015148711", "name": "contactin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148711" }, "gene_names": [ { "name": "CNTN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" } ] }, { "name": "CNTN3", "type": "synonym", "evidence": [ { "id": "XP_015148711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148711" } ] } ], "protein_names": [ { "name": "Contactin-3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18/entry#names_and_taxonomy" } ] }, { "name": "Brain-derived immunoglobulin superfamily protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18/entry#names_and_taxonomy" } ] }, { "name": "Plasmacytoma-associated neuronal glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18/entry#names_and_taxonomy" } ] }, { "name": "contactin-3", "type": "synonym", "evidence": [ { "id": "XP_015148711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148711" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148711.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148711" } ] }, { "annotation": "Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18#function" }, { "database": "UniProtKB", "id": "ARBA00060217", "url": "https://www.uniprot.org/uniprotkb/ARBA00060217#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNTN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18", "locus": { "chromosome": "12", "start_pos": 17076110, "end_pos": 17168309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020369", "url": "https://www.ensembl.org/id/ENSGALG00010020369" } ] } } ], "crossref": [ { "id": "A0A8V0ZE18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04968", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04968", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416101", "url": "https://www.ncbi.nlm.nih.gov/gene/416101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416101", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKLMGAR", "url": "https://omabrowser.org/oma/group/HKLMGAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE18", "url": "https://www.orthodb.org/?gene=A0A8V0ZE18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLLWKQLFLVSLVGCLGADPESSRTKMRSTVSVREGQGVVLLCGTPPRAGELSFAWIFNEYPSFVQEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNSQVLGSPTPLVLRTDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPVPQINWRRTDGMPFPSKIKLRKSNGMIEIPNFQQEDAGLYECITENSRGKNIARGRLTYYAKPHWIQMIKDTEIAVEDTLYWDCRASGKPKPSYRWLKNGEQLSVEGRIQIENGALTISSLNLTDSGRYQCIAENKHGVIYSSAELRVVASAPDFSKNPMKKMIQVQIGSTVDFECKPKASPKARCSWKKGGEQLHENERITLLKDGGLRITNVTKVDAGSYTCVATNQFGTASGTTNLVVTEPTRIILAPSNMDVTVGESVILPCQVQHDPILDISFTWYFNGTLTDFKKDASHFEKVGGSASGDLMIRNIQLKHSGKYVCMVKTEVDSVASAADLIVRGSPGPPEHVRVDEITDTTAQISWQEGTDNHSPVTAYTIQARTPFSVGWQRVTTVPDVIDGNTFTTTVVDLNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEIPPAEVSGGGGSRSELVITWDPIPEELQNGEGFGYVVAFRPFGTTTWIQTVVTSPDTPRYVFRNESILPFSPYEVKVGVYNNKGEGPFSSITTVFSAEEEPTVAPSGVSVTSLSSSVIEVSWKAIPWKMSSGRLLGYEVRYWNNGGKEESSNRVKAAGNETSIRITGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNVTDSRVILNWEEVRAMENESEVTGYKVLYRTSGQNNMNVLNTDKTTAELLLQFNEDYIIEVKATTEGGDGTSSDQILIPRLASMDARGSGPSTLNIFSLSSILPTVFSFTLNSVL", "length": 928, "header": "tr|A0A8V0ZE18-1|A0A8V0ZE18_CHICK Isoform 1 of Contactin-3 OS=Gallus gallus OX=9031 GN=CNTN3 PE=3 SV=1 CANONICAL=A0A8V0ZE18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18/entry#A0A8V0ZE18-1", "sequence": { "sequence": "MMLLWKQLFLVSLVGCLGADPESSRTKMRSTVSVREGQGVVLLCGTPPRAGELSFAWIFNEYPSFVQEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNSQVLGSPTPLVLRTDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPVPQINWRRTDGMPFPSKIKLRKSNGMIEIPNFQQEDAGLYECITENSRGKNIARGRLTYYAKPHWIQMIKDTEIAVEDTLYWDCRASGKPKPSYRWLKNGEQLSVEGRIQIENGALTISSLNLTDSGRYQCIAENKHGVIYSSAELRVVASAPDFSKNPMKKMIQVQIGSTVDFECKPKASPKARCSWKKGGEQLHENERITLLKDGGLRITNVTKVDAGSYTCVATNQFGTASGTTNLVVTEPTRIILAPSNMDVTVGESVILPCQVQHDPILDISFTWYFNGTLTDFKKDASHFEKVGGSASGDLMIRNIQLKHSGKYVCMVKTEVDSVASAADLIVRGSPGPPEHVRVDEITDTTAQISWQEGTDNHSPVTAYTIQARTPFSVGWQRVTTVPDVIDGNTFTTTVVDLNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEIPPAEVSGGGGSRSELVITWDPIPEELQNGEGFGYVVAFRPFGTTTWIQTVVTSPDTPRYVFRNESILPFSPYEVKVGVYNNKGEGPFSSITTVFSAEEEPTVAPSGVSVTSLSSSVIEVSWKAIPWKMSSGRLLGYEVRYWNNGGKEESSNRVKAAGNETSIRITGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNVTDSRVILNWEEVRAMENESEVTGYKVLYRTSGQNNMNVLNTDKTTAELLLQFNEDYIIEVKATTEGGDGTSSDQILIPRLASMDARGSGPSTLNIFSLSSILPTVFSFTLNSVL", "length": 928, "header": "tr|A0A8V0ZE18-1|A0A8V0ZE18_CHICK Isoform 1 of Contactin-3 OS=Gallus gallus OX=9031 GN=CNTN3 PE=3 SV=1 CANONICAL=A0A8V0ZE18-1" }, "locus": { "chromosome": "12", "start_pos": 17147248, "end_pos": 17077966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049209.1", "url": "https://www.ensembl.org/id/ENSGALT00010049209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029095.1", "url": "https://www.ensembl.org/id/ENSGALP00010029095.1" } ] } }, { "isoform_ac": "A0A8V0ZKG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18/entry#A0A8V0ZKG1-1", "sequence": { "sequence": "MMLLWKQLFLVSLVGCLGDPESSRTKMRSTVSVREGQGVVLLCGTPPRAGELSFAWIFNEYPSFVQEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNSQVLGSPTPLVLRTDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPVPQINWRRTDGMPFPSKIKLRKSNGMIEIPNFQQEDAGLYECITENSRGKNIARGRLTYYAKPHWIQMIKDTEIAVEDTLYWDCRASGKPKPSYRWLKNGEQLSVEGRIQIENGALTISSLNLTDSGRYQCIAENKHGVIYSSAELRVVASAPDFSKNPMKKMIQVQIGSTVDFECKPKASPKARCSWKKGGEQLHENERITLLKDGGLRITNVTKVDAGSYTCVATNQFGTASGTTNLVVTEPTRIILAPSNMDVTVGESVILPCQVQHDPILDISFTWYFNGTLTDFKKDASHFEKVGGSASGDLMIRNIQLKHSGKYVCMVKTEVDSVASAADLIVRGSPGPPEHVRVDEITDTTAQISWQEGTDNHSPVTAYTIQARTPFSVGWQRVTTVPDVIDGNTFTTTVVDLNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEIPPAEVSGGGGSRSELVITWDPIPEELQNGEGFGYVVAFRPFGTTTWIQTVVTSPDTPRYVFRNESILPFSPYEVKVGVYNNKGEGPFSSITTVFSAEEEPTVAPSGVSVTSLSSSVIEVSWKAIPWKMSSGRLLGYEVRYWNNGGKEESSNRVKAAGNETSIRITGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNVTDSRVILNWEEVRAMENESEVTGYKVLYRTSGQNNMNVLNTDKTTAELLLQFNEDYIIEVKATTEGGDGTSSDQILIPRLASMDARGSGPSTLNIFSLSSILPTVFSFTLNSVL", "length": 927, "header": "tr|A0A8V0ZKG1-1|A0A8V0ZKG1_CHICK Computationally mapped isoform of Contactin-3 OS=Gallus gallus OX=9031 GN=CNTN3 PE=3 SV=1 CANONICAL=A0A8V0ZE18-1" }, "locus": { "chromosome": "12", "start_pos": 17147248, "end_pos": 17077966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049206.1", "url": "https://www.ensembl.org/id/ENSGALT00010049206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029092.1", "url": "https://www.ensembl.org/id/ENSGALP00010029092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416101", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MQU1-1", "protein_name": "Contactin 3", "gene_name": "CNTN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLSWKHLIFLSFIGCLEGELLLQGPVFVKEPSNSIFPVGSEDKKITLNCEARGNPSPHYRWQLNGSDIDLSMEYRYKLIRGNLVVINPNRNWDTGNYQCFATNSVGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPVPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDSGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVELAVEDSLYWECRASGKPKPSYRWLKNGEALVLEERIQIENGALTISNLNVTDSGMFQCIAENKHGLVYSSAELKVMASAPDFSKTPMKKLIQVQVGSEVNLDCKPRASPRALSSWKKGEVIVQENERTSFLNDGGLKIVNVTKADAGIYTCIAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLATMFTWYFNGALADFRKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPESVKVDEITDTTAQLSWKEGTDNHSPVIAYSVQARTPFSVGWQTATTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVSGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTNWIQTVVTSPDTPRYIFRNESILPFSLYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTTAPSQVSANSLSSSEIEVSWNAIPWKLSNGHLLGYEVRYWNNGGEEDSSSKLKVAGNVTSARLRGLKSNLAYYTAVRAFNSAGTGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITNMDARGCTSAISTVYPVSSYVSVIMFFIVNTLW", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZE18", "url": "https://omabrowser.org/oma/group/A0A8V0ZE18/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7EZG5-1", "protein_name": "Contactin-3", "gene_name": "cntn3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLLWKRLVALSIIGCLAVSLAQAEDAKFSGPSWKREPEDLILPIYSPQQEAVLSCEASGAPSPQYRWSLNGTLIDLGGDERRRLSGGNLIITGLDRDQDSGVYQCTAFNTRGTILSQRATLQFAYLENFKTQTRSAVNVREGQGVVLLCGTPLHSGELTFTWVFNEYPHFVQQDSRRFVSQETGNLYIAKVEPSDVGNYTCVVNNTITKERVFSSPTPLVLRNDGAMGEYEPKIELHFPDTIPAAKGSALKLECFALGNPVPRISWRRTSDVSFPNKVKLKNSNAILEIPSFQQEDTGTYECIAENSRGKNAARGRVSFHATPHWLQTMTDTAMSIEENLFWECKANGKPKPSYSWLKNGESLISEGRVQIENGALSIFSLNLSDGGMYQCVAENKHGIIYSSAELMVLASAPSFSQNPLSQTLKARSGSDVSLDCRPHASPRAISLWKRGTEILQRNERTFLFPNGTLKITNITKRDGGSYTCVAKNQFGTASTTGKLIITEPTRISQSPSSTEITVGESVVLPCQVTADPALDVAFSWAFNGQPIDFHQDADHFERVGGSFSGDLMIRNIQLNHGGKYVCLVDTDVESLSADAILVVKGPPSPPDMVVVEEVTDSTAQLSWSPGQDNGSPITGYAIQGRTPFTVGWQAVDTVPEVINGNTLTATVVGLNAWVEYEFRVLASNSVGMGEPSPPSTKIRTEDSMPDAAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPVGMVTWTRVVISAPSLTRYVFRNDTIPPFSPFNVKVGAFNNRGEGPFSTIATVFSAEEVPSIAPEKVSAKSLSAADIEVTWEPIASIPERVLGYEVVYWEDDTKPDTVGKVRITGNYTAVNVSGLQGNTQYYLAVCAFNTAGTGPQSAPVNITTKKPPPGQPPQNVEWNLIGSQLILQWDPVIALETESEVTGYIVLYRRHRNNDMYSIITNKTSAELTLNPNDNYVIQIKSLSEGGLGEGSEPIHIHQLSMGARGSRSGRLCSLSLSPLLICALSSLGAS", "length": 1029 }, "evidence": [ { "id": "A0A8V0ZE18", "url": "https://omabrowser.org/oma/group/A0A8V0ZE18/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SFM5-1", "protein_name": "Contactin 3", "gene_name": "CNTN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMLSWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGTEDKKITLSCEARGNPTPHYRWQLNGSDVNLSMEYRYKLHGGNLVLINPDRNRDTGSYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYIAKVETSDVGNYTCVVTSTVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPVPQINWRRSDGLPFSNKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIRDVEIAVEDSLYWECRASGKPKPSYRWLKNGEALALEERIQIENGALTISNLNVTDSGMFQCIAENKHGLIYSSAELKVVASAPDFSKTPMKKLIQVQVGSEVSLDCKPRASPRALSSWKKGDVLVQETDRISFLKDGGLKIANVTKADVGIYTCIAENQFGKANGSTHLVVTEPTRIILAPSNMDVSVGESIILPCQVQHDPLLDITFTWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGRYVCMVQTEVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGTDNHSPVISYSVQARTPFSVGWQTATTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVSGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTNWIQTVVTSPDTPRYVFRNDSILPFSLYEVKVGVYNNKGEGPFSPVTAVFSAEEEPTIAPSQVSANSLSSSEIEVSWNAVPWKLSNGHLLGYELRYWNNGGEEESSSKLKVAGNVTSARLRGLKSNLAYYTAVRAFNSAGTGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVRAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITNMDARGCTSAICIVHPVSSSISLVLFFIVNALW", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZE18", "url": "https://omabrowser.org/oma/group/A0A8V0ZE18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q07409-1", "protein_name": "Contactin-3", "gene_name": "Cntn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLSWKQLILLSFIGCLAGELLLQGPVFIKEPSNSIFPVDSEDKKITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFAYLENFKTRMRSTVSVREGQGVVLLCGPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNTRVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVRLECFALGNPVPQINWRRSDGMPFPNKIKLRKFNGMLEIQNFQQEDTGSYECIAENSRGKNVARGRLTYYAKPYWLQLLRDVEIAVEDSLYWECRASGKPKPSYRWLKNGDALVLEERIQIENGALTITNLNVTDSGMFQCIAENKHGLIYSSAELKVVASAPDFSRNPMKKMVQVQVGSLVILDCKPRASPRALSFWKKGDMMVREQARVSFLNDGGLKIMNVTKADAGTYTCTAENQFGKANGTTHLVVTEPTRIILAPSNMDVAVGESVILPCQVQHDPLLDIMFAWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQSVRTVPEVIDGKTHTATVVELNPWVEYEFRIVASNKIGGGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNNGGEEESSRKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVHVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNIHPLSGYMSVLLFFIVNALW", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZE18", "url": "https://omabrowser.org/oma/group/A0A8V0ZE18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P232-1", "protein_name": "Contactin-3", "gene_name": "CNTN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVLFLIVYVLW", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZE18", "url": "https://omabrowser.org/oma/group/A0A8V0ZE18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 500, "end_pos": 598, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE18" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 109, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 795, "end_pos": 797 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 831, "end_pos": 833 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE30-1", "uniprot_ac": "A0A8V0ZE30", "uniprot_id": "A0A8V0ZE30_CHICK", "mass": { "chemical_mass": 266943.0, "monoisotopic_mass": 266943.0 }, "refseq": { "ac": "XP_015134598", "name": "CCR4-NOT transcription complex subunit 1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134598" }, "gene_names": [ { "name": "CNOT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ] }, { "name": "CNOT1", "type": "synonym", "evidence": [ { "id": "XP_015134598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134598" } ] } ], "protein_names": [ { "name": "CCR4-NOT transcription complex subunit 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30/entry#names_and_taxonomy" } ] }, { "name": "CCR4-NOT transcription complex subunit 1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_015134598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134598" } ] }, { "name": "CCR4-associated factor 1", "type": "synonym", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134598" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNOT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30", "locus": { "chromosome": "11", "start_pos": 1433769, "end_pos": 1487261, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021665", "url": "https://www.ensembl.org/id/ENSGALG00010021665" } ] } } ], "crossref": [ { "id": "cd20710", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20710", 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"MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECASLITKPNFISTLSYAIDNPLHYQKSLKPSPHLFAQLSKVIKLSKVQEVIFGLALLNSFSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGIAKTMMESSLADFMQEVGYGFCTSIEECRNIIMQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLDFKVVTYELDHPGFQIRDSKGLHIVVFGIQRGLGMEVFPVNAIYRPWKHAEGQLSFIQHSLINPDIFCFADYPCHAVTTDILKAPPEDDNREIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDSLAGMASLSLGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTQNQTTGFSGIGGLSSQLPVGGLTTGSLTGIGTGALGLPAVNNDPFVQRKLSTSGLSQPTFQQSKMKPSDLSQVWPEANQNFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSNIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFASKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFIQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVSTIVTTSTTTTVAKTITITRPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPPENVQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSVRSVVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGSLLKDKDRLKNLDEQLSAPKKDVKQPEELPPITTTTASTTPATSTTCTATVPPQPQYSYHDINVYSLGGLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRVAAHHMMRNLTAGMAMITCREPLLMSIATNLKNSFATALRAASPQQRDMMEQAAAQLAQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRRYCDPVVLTYQAERMPEQIRLKVGGVDPKQLAVYEEFARNVPGFLPTNDLTQPTGFLAQPMKQQAWATDDVAQIYDKCMTELEQHLQSIPHTLAMNPQAQALRSLLEAVVVARNSRDAIAALGLLQKAVEGLLDATSGADADLLLRYRECHLLVLKALQDGRAYGSPWCNKQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHVTEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRSNYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHEVRQGEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNIQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS", "length": 2377, "header": "tr|A0A8V0ZE30-1|A0A8V0ZE30_CHICK Isoform 1 of CCR4-NOT transcription complex subunit 1 OS=Gallus gallus OX=9031 GN=CNOT1 PE=1 SV=1 CANONICAL=A0A8V0ZE30-1" }, "locus": { "chromosome": "11", "start_pos": 1482415, "end_pos": 1434830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052640.1", "url": "https://www.ensembl.org/id/ENSGALT00010052640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031546.1", "url": "https://www.ensembl.org/id/ENSGALP00010031546.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.", "journal": "Commun. Biol.", "date": "2023", "authors": "Levdansky Yevgen, Raisch Tobias, Deme Justin C, Pekovic Filip, Elmlund Hans, Lea Susan M, Valkov Eugene", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "reference": [ { "type": "PubMed", "id": "37460791", "url": "https://glygen.org/publication/PubMed/37460791" } ] } ], "pathway": [ { "id": "R-GGA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-GGA-6804115", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804115", "resource": "Reactome", "description": "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "pmid": "" }, { "name": "nuclear retinoic acid receptor binding", "id": "GO:0042974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE30" } ], "pmid": "" }, { "name": "armadillo repeat domain 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138904.1. 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE73-1", "uniprot_ac": "A0A8V0ZE73", "uniprot_id": "A0A8V0ZE73_CHICK", "mass": { "chemical_mass": 63521.0, "monoisotopic_mass": 63521.0 }, "refseq": {}, "gene_names": [ { "name": "BIN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73" } ] } ], "protein_names": [ { "name": "Myc box-dependent-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#names_and_taxonomy" } ] }, { "name": "Amphiphysin II", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#names_and_taxonomy" } ] }, { "name": "Amphiphysin-like protein", 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"url": "https://www.ensembl.org/id/ENSGALG00010021684" } ] } } ], "crossref": [ { "id": "A0A8V0ZE73", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE73", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011541", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011541", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07611", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07611", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12139", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12139", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424228", "url": "https://www.ncbi.nlm.nih.gov/gene/424228", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003005", "url": 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Pathway" ] }, { "id": "A0A8V0ZE73", "url": "https://www.orthodb.org/?gene=A0A8V0ZE73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZJN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZ04", "url": "https://www.orthodb.org/?gene=F1NZ04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46514:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46514:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ04", "url": "https://www.uniprot.org/uniprotkb/F1NZ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ04-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLSEGTRLQKDLRTYLASVKAMHEASKKLTECLQEVYEPDWPGRDDTNKIAENNDLLWTDFHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHFEALQTAKKKDETKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELVKAQKVFEEMNIDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLHDVLLGLDKQYSGNAFPIKAQPRKKTKLFARLRKKMSSDSTPAKANKSPSPPPDGSPITSPETKTVNHELEPSTLEAPGASIPKSPSQLRKGPPVPPPPKVTPSKEIKQENIISLFDDNFVPEISVTTPSQFDAPGPFQEGASLLDLDFDPIKPDATMGKTPTPASQSLPWDLWEPTEAAHAGAEAAGSEAAAGAEASKTEGDSGSSSLPAVVVETFPATVNGTVEGGASSERADMPPGFLFKVQAMHDYTATDSDELQLKAGDVVLVIPFENPEEQDEGWLMGVKESDWIQHKELDQCRGVFPENFTERVQ", "length": 575, "header": "tr|A0A8V0ZE73-1|A0A8V0ZE73_CHICK Isoform 1 of Myc box-dependent-interacting protein 1 OS=Gallus gallus OX=9031 GN=BIN1 PE=1 SV=1 CANONICAL=A0A8V0ZE73-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#A0A8V0ZE73-1", "sequence": { "sequence": "MAELGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLSEGTRLQKDLRTYLASVKAMHEASKKLTECLQEVYEPDWPGRDDTNKIAENNDLLWTDFHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHFEALQTAKKKDETKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELVKAQKVFEEMNIDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLHDVLLGLDKQYSGNAFPIKAQPRKKTKLFARLRKKMSSDSTPAKANKSPSPPPDGSPITSPETKTVNHELEPSTLEAPGASIPKSPSQLRKGPPVPPPPKVTPSKEIKQENIISLFDDNFVPEISVTTPSQFDAPGPFQEGASLLDLDFDPIKPDATMGKTPTPASQSLPWDLWEPTEAAHAGAEAAGSEAAAGAEASKTEGDSGSSSLPAVVVETFPATVNGTVEGGASSERADMPPGFLFKVQAMHDYTATDSDELQLKAGDVVLVIPFENPEEQDEGWLMGVKESDWIQHKELDQCRGVFPENFTERVQ", "length": 575, "header": "tr|A0A8V0ZE73-1|A0A8V0ZE73_CHICK Isoform 1 of Myc box-dependent-interacting protein 1 OS=Gallus gallus OX=9031 GN=BIN1 PE=1 SV=1 CANONICAL=A0A8V0ZE73-1" }, "locus": { "chromosome": "7", "start_pos": 23388858, "end_pos": 23307417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052687.1", "url": "https://www.ensembl.org/id/ENSGALT00010052687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031593.1", "url": "https://www.ensembl.org/id/ENSGALP00010031593.1" } ] } }, { "isoform_ac": "A0A8V0ZJN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#A0A8V0ZJN4-1", "sequence": { "sequence": "MAELGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLSEGTRLQKDLRTYLASVKAMHEASKKLTECLQEVYEPDWPGRDDTNKIAENNDLLWTDFHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHFEALQTAKKKDETKIAKAEEELVKAQKVFEEMNIDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLHDVLLGLDKQYSGNAFPIKAQPRKKTKLFARLRKKMSSDSTPAKANKSPSPPPDGSPITSPETKTVNHELEPSTLEAPGASIPKSPSQLRKGPPVPPPPKVTPSKEIKQENIISLFDDNFVPEISVTTPSQFDAPGPFQEGASLLDLDFDPIKPDATMGKTPTPASQPTEAAHAGAEAAGSEAAAGAEASKTEGDSGSSSLPAVVVETFPATVNGTVEGGASSERADMPPGFLFKVQAMHDYTATDSDELQLKAGDVVLVIPFENPEEQLDVGATAMNSRLSKLQRDEGWLMGVKESDWIQHKELDQCRGVFPENFTERVQ", "length": 553, "header": "tr|A0A8V0ZJN4-1|A0A8V0ZJN4_CHICK Computationally mapped isoform of Bridging integrator 1 OS=Gallus gallus OX=9031 GN=BIN1 PE=1 SV=1 CANONICAL=A0A8V0ZE73-1" }, "locus": { "chromosome": "7", "start_pos": 23388858, "end_pos": 23307417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052678.1", "url": "https://www.ensembl.org/id/ENSGALT00010052678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031584.1", "url": "https://www.ensembl.org/id/ENSGALP00010031584.1" } ] } }, { "isoform_ac": "A0A8V0ZLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#A0A8V0ZLJ5-1", "sequence": { "sequence": "MAELGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLSEGTRLQKDLRTYLASVKAMHEASKKLTECLQEVYEPDWPGRDDTNKIAENNDLLWTDFHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHFEALQTAKKKDETKIAKAEEELVKAQKVFEEMNIDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLHDVLLGLDKQYSGNAFPIKAQPRKKTKLFARLRKKMSSDSTPAKANKSPSPPPDGSPITSPETKTVNHELEPSTLEAPGASIPKSPSQLRKGPPVPPPPKVTPSKEIKQENIISLFDDNFVPEISVTTPSQFDAPGPFQEGASLLDLDFDPIKPDATMGKTPTPASQPTEAAHAGAEAAGSEAAAGAEASKTEGDSGSSSLPAVVVETFPATVNGTVEGGASSERADMPPGFLFKVQAMHDYTATDSDELQLKAGDVVLVIPFENPEEQDEGWLMGVKESDWIQHKELDQCRGVFPENFTERVQ", "length": 536, "header": "tr|A0A8V0ZLJ5-1|A0A8V0ZLJ5_CHICK Computationally mapped isoform of Bridging integrator 1 OS=Gallus gallus OX=9031 GN=BIN1 PE=1 SV=1 CANONICAL=A0A8V0ZE73-1" }, "locus": { "chromosome": "7", "start_pos": 23388858, "end_pos": 23307417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052695.1", "url": "https://www.ensembl.org/id/ENSGALT00010052695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031601.1", "url": "https://www.ensembl.org/id/ENSGALP00010031601.1" } ] } }, { "isoform_ac": "F1NZ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE73/entry#F1NZ04-1", "sequence": { "sequence": "MAELGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLSEGTRLQKDLRTYLASVKAMHEASKKLTECLQEVYEPDWPGRDDTNKIAENNDLLWTDFHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHFEALQTAKKKDETKIAKAEEELVKAQKVFEEMNIDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLHDVLLGLDKQYSGNAFPIKAQPSDSTPAKANKSPSPPPDGSPITSPETKTVNHELEPSTLEAPGASIPKSPSQPTEAAHAGAEAAGSEAAAGAEASKTEGDSGSSSLPAVVVETFPATVNGTVEGGASSERADMPPGFLFKVQAMHDYTATDSDELQLKAGDVVLVIPFENPEEQDEGWLMGVKESDWIQHKELDQCRGVFPENFTERVQ", "length": 442, "header": "tr|F1NZ04-1|A0A8V0ZE73_CHICK Computationally mapped isoform of Myc box-dependent-interacting protein 1 OS=Gallus gallus OX=9031 GN=BIN1 PE=1 SV=1 CANONICAL=A0A8V0ZE73-1" }, "locus": { "chromosome": "7", "start_pos": 23388858, "end_pos": 23307417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052700.1", "url": "https://www.ensembl.org/id/ENSGALT00010052700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031606.1", "url": "https://www.ensembl.org/id/ENSGALP00010031606.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZE93-1", "uniprot_ac": "A0A8V0ZE93", "uniprot_id": "A0A8V0ZE93_CHICK", "mass": { "chemical_mass": 106704.0, "monoisotopic_mass": 106704.0 }, "refseq": { "ac": "XP_040557412", "name": "formin-binding protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557412" }, "gene_names": [ { "name": "FNBP4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZE93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93" } ] }, { "name": "FNBP4", "type": "synonym", "evidence": [ { "id": "XP_040557412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557412" } ] } ], "protein_names": [ { "name": "Formin binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZE93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93/entry#names_and_taxonomy" } ] }, { "name": "formin-binding protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040557412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557412" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557412" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FNBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93", "locus": { "chromosome": "5", "start_pos": 592255, "end_pos": 582641, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021695", "url": "https://www.ensembl.org/id/ENSGALG00010021695" } ] } } ], "crossref": [ { "id": "A0A8V0ZE93", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZE93", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426631", "url": "https://www.ncbi.nlm.nih.gov/gene/426631", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QDGDGHR", "url": "https://omabrowser.org/oma/group/QDGDGHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE93", "url": "https://www.orthodb.org/?gene=A0A8V0ZE93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46697", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46697", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46697:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46697:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKSRSAPGRRPILQLSPPGPRREDAGPSGQAAEGTESGSEPDEAEAVPEPPRSAPNPPPPAPAAVKPTGGLCLLGAYADSDDEEGEGGEKPARPAGANGNSSTDIDSTLANFLAEIDAITAPPQPAEPTPAAAAPPPTPPRPEPKEPGTAAGTTTANGTDAAAAPEWQYDTQCSLAGVGELEMGDWQEVWDENTGCYYYWNTQSNEVTWELPQYLAAQVQGLQHYQPSSTAAGTNGSFTAAAEPLAQEKTGPVSAARPGAKREVKKEVNEGVQALSNSEEEKKGVAAALLAPLVPDVVKEEEERWRRKVICKEEVEPPPEEEVKAEEVPAASEEPKPGKDPLEDTLQEELCSVVQSGESGEEEEEQDTLELEIVLERKKAELRALEEGDGSVSGSSPLSDGSQSASQDATRRLTSKRGKWKLFVGAASPDSASRGSSKTGRESPEAGEAAVSTEAADGPSDKDAESEEPQEKVKAQVAPKIEEEEQDLKFQIGELANTLTSKLEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRISGSPLLTNSSDKGQTSTHRRNEEQDFCLLPAGSIGAISMLTSTQESRSGSSPTERTKTKDSRAPTESPTVLPNHLPKRKESIPATPLRVQQSSVPVLQPPLPLEMPPPPPPPPDSPPPPPPPPPPPGEDGEIQEVEMEDEGGEEPPAPGTEEDALLKPLLRPAVSRSQGAAEPSPALLLSAKPQKRKAAEMNPELMQRTATIGSCPVIYSQPLMAASKYQPSPVPLTSLRPRQRLQGEMQSRANLRLPPGHAVPQPSSMAMQPGYLGVTAPAAPSVMSYSECAMPAGLAAVPPAPARGSLPATSTAEHPPPPPPPQTPPPPTPKAPPPPDKPEKPRKGRKEKSKKGKTKMPSLVKKWQSIQRELDEEENSSSSEEDRETTAQRRIEEWKQQQLLSGMAERNANFEALPEDWRARLKRRKTASST", "length": 996, "header": "tr|A0A8V0ZE93-1|A0A8V0ZE93_CHICK Isoform 1 of Formin binding protein 4 OS=Gallus gallus OX=9031 GN=FNBP4 PE=4 SV=1 CANONICAL=A0A8V0ZE93-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93/entry#A0A8V0ZE93-1", "sequence": { "sequence": "MGKKSRSAPGRRPILQLSPPGPRREDAGPSGQAAEGTESGSEPDEAEAVPEPPRSAPNPPPPAPAAVKPTGGLCLLGAYADSDDEEGEGGEKPARPAGANGNSSTDIDSTLANFLAEIDAITAPPQPAEPTPAAAAPPPTPPRPEPKEPGTAAGTTTANGTDAAAAPEWQYDTQCSLAGVGELEMGDWQEVWDENTGCYYYWNTQSNEVTWELPQYLAAQVQGLQHYQPSSTAAGTNGSFTAAAEPLAQEKTGPVSAARPGAKREVKKEVNEGVQALSNSEEEKKGVAAALLAPLVPDVVKEEEERWRRKVICKEEVEPPPEEEVKAEEVPAASEEPKPGKDPLEDTLQEELCSVVQSGESGEEEEEQDTLELEIVLERKKAELRALEEGDGSVSGSSPLSDGSQSASQDATRRLTSKRGKWKLFVGAASPDSASRGSSKTGRESPEAGEAAVSTEAADGPSDKDAESEEPQEKVKAQVAPKIEEEEQDLKFQIGELANTLTSKLEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRISGSPLLTNSSDKGQTSTHRRNEEQDFCLLPAGSIGAISMLTSTQESRSGSSPTERTKTKDSRAPTESPTVLPNHLPKRKESIPATPLRVQQSSVPVLQPPLPLEMPPPPPPPPDSPPPPPPPPPPPGEDGEIQEVEMEDEGGEEPPAPGTEEDALLKPLLRPAVSRSQGAAEPSPALLLSAKPQKRKAAEMNPELMQRTATIGSCPVIYSQPLMAASKYQPSPVPLTSLRPRQRLQGEMQSRANLRLPPGHAVPQPSSMAMQPGYLGVTAPAAPSVMSYSECAMPAGLAAVPPAPARGSLPATSTAEHPPPPPPPQTPPPPTPKAPPPPDKPEKPRKGRKEKSKKGKTKMPSLVKKWQSIQRELDEEENSSSSEEDRETTAQRRIEEWKQQQLLSGMAERNANFEALPEDWRARLKRRKTASST", "length": 996, "header": "tr|A0A8V0ZE93-1|A0A8V0ZE93_CHICK Isoform 1 of Formin binding protein 4 OS=Gallus gallus OX=9031 GN=FNBP4 PE=4 SV=1 CANONICAL=A0A8V0ZE93-1" }, "locus": { "chromosome": "5", "start_pos": 592165, "end_pos": 582693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052707.1", "url": "https://www.ensembl.org/id/ENSGALT00010052707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031613.1", "url": "https://www.ensembl.org/id/ENSGALP00010031613.1" } ] } }, { "isoform_ac": "A0A8V0ZLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93/entry#A0A8V0ZLD5-1", "sequence": { "sequence": "MGKKSRSAPGRRPILQLSPPGPRREDAGPSGQAAEGTESGSEPDEAEAVPEPPRSAPNPPPPAPAAVKPTGGLCLLGAYADSDDEEGEGGEKPARPAGANGNSSTDIDSTLANFLAEIDAITAPPQPAEPTPAAAAPPPTPPRPEPKEPGTAAGTTTANGTDAAAAPEWQYDTQCSLAGVGELEMGDWQEVWDENTGCYYYWNTQSNEVTWELPQYLAAQVQGLQHYQPSSTAAGTNGSFTAAAEPLAQEKTGPVSAARPGAKREVKKEVNEGVQALSNSEEEKKGVAAALLAPLVPDVVKEEEERWRRKVICKEEVEPPPEEEVKAEEVPAASEEPKPGKDPLEDTLQEELCSVVQSGESGEEEEEQDTLELEIVLERKKAELRALEEGDGSVSGSSPLSDGSQSASQDATRRLTSKRGKWKLFVGAASPDSASRGSSKTGRESPEAGEAAVSTEAADGPSDKDAESEEPQEKVKAQVAPKIEEEEQDLKFQIGELANTLTSKLEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDREHRRYFYVNEHSGESQWEFPDGEDEDEGQQSADRKPDGPPKPPPKEKGEHPGDATESSTGSLCKESFSGQVPATSLMPLTPFWTLLQSSVPVLQPPLPLEMPPPPPPPPDSPPPPPPPPPPPGEDGEIQEVEMEDEGGEEPPAPGTEEDALLKPLLRPAVSRSQGAAEPSPALLLSAKPQKRKAAEMNPELMQRTATIGSCPVIYSQPLMAASKYQPSPVPLTSLRPRQRLQGEMQSRANLRLPPGHAVPQPSSMAMQPGYLGVTAPAAPSVMSYSECAMPAGLAAVPPAPARGSLPATSTAEHPPPPPPPQTPPPPTPKAPPPPDKPEKPRKGRKEKSKKGKTKMPSLVKKWQSIQRELDEEENSSSSEEDRETTAQRRIEEWKQQQLLSGMAERNANFEALPEDWRARLKRRKTASST", "length": 991, "header": "tr|A0A8V0ZLD5-1|A0A8V0ZLD5_CHICK Computationally mapped isoform of Formin-binding protein 4 OS=Gallus gallus OX=9031 GN=FNBP4 PE=4 SV=1 CANONICAL=A0A8V0ZE93-1" }, "locus": { "chromosome": "5", "start_pos": 592165, "end_pos": 582693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052711.1", "url": "https://www.ensembl.org/id/ENSGALT00010052711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031617.1", "url": "https://www.ensembl.org/id/ENSGALP00010031617.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 894, "start_aa": "Thr", "end_pos": 894, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr894", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MAK1-1", "protein_name": "Formin-binding protein 4", "gene_name": "Fnbp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIDYAPGRRAPAPLICRRSLLALGLVMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPETDSTAAATSQSVPAAATAAAATSPAVPATAAPEDSPSEDEQEVVVEVPNVVQNPPKPVMPTRPTTVKATGGLCLLGAYADSDDDENDISEKTAQSKESNGNQSTDIDSTLANFLAEIDAITAPQPVAPVVASAPPPTPPRPEPKEAATPALSSAASNGTDAAQTAGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQTSSVTGTEAAFVVNTDIYAKEKMIPASSNKSGPVIAKREVKKEVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSEAKETSTAAEETGPSIKPPEVAMDSTEDPSQEDLCSVVQSGESEEEEEEEQDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMPRIMSKRGKWKMFVRATSPESTSRSSSKTGRETPENGETAIGAEDSEKINENSDKEAEVEESSEKIKVQIAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEESQAQEVRDESLPKLTEKDKTCTDSNSAESSENSTGSLCKESFSGQVSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTVVTSQSSVDSTASSPPSTKAVKRKAPEISTAVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVSVSHAAAGMGHPTRGMSLQSNYLGLAAAPAILSYAECSVPIGVTTPSLQPAQARGTVAAPAVVEPPPPPPPPPTSTPPPPPPAPKGPPPEKTRKGKREKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKMAPNT", "length": 1048 }, "evidence": [ { "id": "A0A8V0ZE93", "url": "https://omabrowser.org/oma/group/A0A8V0ZE93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGN0-1", "protein_name": "Formin-binding protein 4", "gene_name": "fnbp4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKKTRAGTGRRTILQLSPPGPNRSATGTAREDGAASGSEDETDGNTDGQREANVNVVMKTPAVKATQGLSLLGAYEDSEDEDAVENASKAKHNQSGDIDSTLANFMAEIDAITTQPTDESGTEPSAPVPTPPRPEPKTDPQAQNGPAQEFQYNTQYSLAGAGLEMGDWQEVWDENTGCYYYWNTQTNEVAWELPHYLADQMQNLHYSGSSSVNGNGVAHSSYPEPQSTAVAPAAKRELKKKDVIESVVALTSEEEERRGVAATLLAPLIPEEVKEAEEKWRKKTLGMEETPEAAPEQEKDTIPFLDSPAIRDTESQNNQRSRNQSAESSDQEEEEQEEDTMELELALERKKAELRALEEGDASAGGSSPCSEASQDGPRTLLLKKNKWKTAFLRAPSPDSSSRGSDKAGWATPEQSDTAHSKPAEKQGEDDENEKPVSKALQKEEEDLKFQIGELANTLTSKMEFLGIDKKAISNFQLLLLQTETRIADWREGALNGSYLRRRLQEAAEHIKHYELNATPKGWSCHWDREHRRYFYMNERTSASQWEFPVGGEEEEAKPPLPSATAHGDSSQPSAETTGVVTGDVQSYWMVPPPPQPPLPPLPPEHPPPPPTEQPPPPPPPPESPPPPPPPPLEDDGEIEEVEMEDEESEPPAPGTEEFKAAEAAALGLAARAQKRKALGSVPLPSMATIGSSPILYTQTIATPAPLLVGSAYWGMTAAIAPPLPTESIVPPMPALPPQPPPPVSQPPPPLEPISKVLTDKTKKLKKEKAKKSKTKMPSLVKKWQSIQKELDEEEKSSSSDEDRDQLNNRRIEEWKQQQLSTGKAGKNANFEALPDDWRERLLKKRKMMQSS", "length": 853 }, "evidence": [ { "id": "A0A8V0ZE93", "url": "https://omabrowser.org/oma/group/A0A8V0ZE93/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZQ03-1", "protein_name": "Formin-binding protein 4", "gene_name": "Fnbp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPEADSTAAATSQSAPAAATAAAATSPAVPASAAPEDSPSEDEQEVVVEVPNVVQNPPTPVMTTRPTAVKATGGLCLLGAYADSDDDESDVSEKTAQSKEANGNQATDIDSTLANFLAEIDAITAPQPAAPVVASAPPPTPPRPEPKEAATPALSPTASNGSDTAQTPGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVTGTEAAFVVNTDMYTKERTTAASSSKSGPVITKREVKKEVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSETKETSTASEETGPSIKPPEVMMDGTEDPSQEELCSVVQSGESEEEEEEEEQDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGVRRIMSKRGKWKMFVRATSPESTSRSSSKTGRDSPENGETAIGAEDSEKIDEISDKETEVEESSEKIKVQLAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEESQTKEVRDESLPKLTVKDKTCTDPNSTESSENPTGSLCKESFSGQVSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTAVTSQSLVDSTASSPPSNKAVKRKAPEMSTSVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVGMAHQAVSASHAAAAGVGHQARGMSLQSNYLGLAAAPALMSYAECSVPIGVTTPSLQPAQARGTMAAPAVVEPPPPPPPPPTPTPPPPPPAPKVPPPEKTRKGKKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRARLKRRKMAPST", "length": 1031 }, "evidence": [ { "id": "A0A8V0ZE93", "url": "https://omabrowser.org/oma/group/A0A8V0ZE93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3X1-1", "protein_name": "Formin-binding protein 4", "gene_name": "FNBP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT", "length": 1017 }, "evidence": [ { "id": "A0A8V0ZE93", "url": "https://omabrowser.org/oma/group/A0A8V0ZE93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZE93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 941, "end_pos": 943, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZE93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE93" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 216, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 70, 131, 140, 894 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 941, "end_pos": 943 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEA3-1", "uniprot_ac": "A0A8V0ZEA3", "uniprot_id": "A0A8V0ZEA3_CHICK", "mass": { "chemical_mass": 12611.0, "monoisotopic_mass": 12611.0 }, "refseq": {}, "gene_names": [ { "name": "GYPC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" } ] } ], "protein_names": [ { "name": "Glycophorin C", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GYPC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3", "locus": { "chromosome": "7", "start_pos": 23644852, "end_pos": 23676116, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021698", "url": "https://www.ensembl.org/id/ENSGALG00010021698" } ] } } ], "crossref": [ { "id": "A0A8V0ZEA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47614:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47614:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDKDPKTRLYFDQLQRCWLGNAYLCAFTFTEDGDVENSSAGADVAVIGGVIAAVVFVLICLLVVMVRYMHRHKGTYHTNEAKGTEFAESADAALKNDPALQEAVDESKKEYFI", "length": 114, "header": "tr|A0A8V0ZEA3-1|A0A8V0ZEA3_CHICK Isoform 1 of Glycophorin C OS=Gallus gallus OX=9031 GN=GYPC PE=4 SV=1 CANONICAL=A0A8V0ZEA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3/entry#A0A8V0ZEA3-1", "sequence": { "sequence": "MGDKDPKTRLYFDQLQRCWLGNAYLCAFTFTEDGDVENSSAGADVAVIGGVIAAVVFVLICLLVVMVRYMHRHKGTYHTNEAKGTEFAESADAALKNDPALQEAVDESKKEYFI", "length": 114, "header": "tr|A0A8V0ZEA3-1|A0A8V0ZEA3_CHICK Isoform 1 of Glycophorin C OS=Gallus gallus OX=9031 GN=GYPC PE=4 SV=1 CANONICAL=A0A8V0ZEA3-1" }, "locus": { "chromosome": "7", "start_pos": 23653570, "end_pos": 23649954, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052717.1", "url": "https://www.ensembl.org/id/ENSGALT00010052717.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031623.1", "url": "https://www.ensembl.org/id/ENSGALP00010031623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" } ], "pmid": "" }, { "name": "cortical cytoskeleton", "id": "GO:0030863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030863", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA3" }, { "id": "SM00294", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurexin/syndecan/glycophorin C", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 84, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEB1-1", "uniprot_ac": "A0A8V0ZEB1", "uniprot_id": "A0A8V0ZEB1_CHICK", "mass": { "chemical_mass": 112870.0, "monoisotopic_mass": 112870.0 }, "refseq": { "ac": "XP_004944760", "name": "contactin-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944760" }, "gene_names": [ { "name": "CNTN6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1" } ] }, { "name": "CNTN6", "type": "synonym", "evidence": [ { "id": "XP_004944760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944760" } ] } ], "protein_names": [ { "name": "Contactin-3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1/entry#names_and_taxonomy" } ] }, { "name": "Brain-derived immunoglobulin superfamily protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1/entry#names_and_taxonomy" } ] }, { "name": "Plasmacytoma-associated neuronal glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1/entry#names_and_taxonomy" } ] }, { "name": "contactin-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944760" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944760.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944760" } ] }, { "annotation": "Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1#function" }, { "database": "UniProtKB", "id": "ARBA00060217", "url": "https://www.uniprot.org/uniprotkb/ARBA00060217#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNTN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1", "locus": { "chromosome": "12", "start_pos": 17828686, "end_pos": 17701691, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020425", "url": "https://www.ensembl.org/id/ENSGALG00010020425" } ] } } ], "crossref": [ { "id": "A0A8V0ZEB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427597", "url": "https://www.ncbi.nlm.nih.gov/gene/427597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427597", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICNVTRS", "url": "https://omabrowser.org/oma/group/ICNVTRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEB1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLWKLIILLPFTSCSTEEETLHGPIFIQEPYDITYSMGSVNPEVLLNCTAKGYPLPSYRWKQNGTDIDLTMSYHYRLVGGSLAINNPRKKQDIGTYQCLATNSFGTILSRKAKLQFAYLENFEMKTRSTVSVREGQGVVLLCGPPPHHGGLSFAWTFNNNTLYVQEDRRRFVSQETGNLYIAKVEPWDVGNYTCVVTNSKAGRSVQGPPTPLTLRSDGVMGEYEPKIEARFPETTYAAKGSSAKLECFALGNPVPSISWRRSDGNSLTKKIKHDKNKGVLEIPDVQQEDGGSYECIAENIRGRNIARGQLFVYALPEWDKKIENAFLSLYDSLFWECKAKGKPTPSYSWLKNGQPLMSEERIQVENGTLIIPMLNMSDSGLYQCVAENKYDTIYASAELRVIAAAPDFSKNPVKKTSIVQVGGEVTIGCRPSASPRAAIDWRKGPEVLRLNKRALLLEDGSLRLYNITKSDAGVYTCIATNQFGVARNSGNLIVKERTVITIAPSNMDVTVGESIVLPCQVSHDPSIAVAFTWSFSGNQIDFKRGMPHFERIGGESVGDLMIRNIQLHHSGKYVCMVQTTLDSQSTAVDIIVRGPPGPPEDVRVEHISSTTAVLSWKSGRDNNSPVQIYSIQTRTPFSVGWQAVSTVPEVLNGRTHKATVVDLSPWVEYEFRVVASNSVGTGEPSKPSALLKTKAAVPTVAPTNVSGGGGSRSELVITWEPVPEELQNGEGFGYIIMFRPLGSTTWTKAAVAPIEASKYVYRNESITPLSPFEVKVGVYNNEGEGTLSSISIVYAGEDEPQIAPAGTSALSISAAEVEVSWQPVAWNRHTGRVLGYEVLYWTDDPKESTAGKVRVNGNVTAKNITGLKANTVYFATVRAYNTAGTGPSSAPVNVTTKKSPPSQPPANIAWKLTNSKICLNWEHVKTMENESEVLGYKILYRQNRHSKAHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKISSLSSGGIKLSPRELYTLASGILLLSFVLTYSFP", "length": 1028, "header": "tr|A0A8V0ZEB1-1|A0A8V0ZEB1_CHICK Isoform 1 of Contactin-3 OS=Gallus gallus OX=9031 GN=CNTN6 PE=3 SV=1 CANONICAL=A0A8V0ZEB1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1/entry#A0A8V0ZEB1-1", "sequence": { "sequence": "MVLLWKLIILLPFTSCSTEEETLHGPIFIQEPYDITYSMGSVNPEVLLNCTAKGYPLPSYRWKQNGTDIDLTMSYHYRLVGGSLAINNPRKKQDIGTYQCLATNSFGTILSRKAKLQFAYLENFEMKTRSTVSVREGQGVVLLCGPPPHHGGLSFAWTFNNNTLYVQEDRRRFVSQETGNLYIAKVEPWDVGNYTCVVTNSKAGRSVQGPPTPLTLRSDGVMGEYEPKIEARFPETTYAAKGSSAKLECFALGNPVPSISWRRSDGNSLTKKIKHDKNKGVLEIPDVQQEDGGSYECIAENIRGRNIARGQLFVYALPEWDKKIENAFLSLYDSLFWECKAKGKPTPSYSWLKNGQPLMSEERIQVENGTLIIPMLNMSDSGLYQCVAENKYDTIYASAELRVIAAAPDFSKNPVKKTSIVQVGGEVTIGCRPSASPRAAIDWRKGPEVLRLNKRALLLEDGSLRLYNITKSDAGVYTCIATNQFGVARNSGNLIVKERTVITIAPSNMDVTVGESIVLPCQVSHDPSIAVAFTWSFSGNQIDFKRGMPHFERIGGESVGDLMIRNIQLHHSGKYVCMVQTTLDSQSTAVDIIVRGPPGPPEDVRVEHISSTTAVLSWKSGRDNNSPVQIYSIQTRTPFSVGWQAVSTVPEVLNGRTHKATVVDLSPWVEYEFRVVASNSVGTGEPSKPSALLKTKAAVPTVAPTNVSGGGGSRSELVITWEPVPEELQNGEGFGYIIMFRPLGSTTWTKAAVAPIEASKYVYRNESITPLSPFEVKVGVYNNEGEGTLSSISIVYAGEDEPQIAPAGTSALSISAAEVEVSWQPVAWNRHTGRVLGYEVLYWTDDPKESTAGKVRVNGNVTAKNITGLKANTVYFATVRAYNTAGTGPSSAPVNVTTKKSPPSQPPANIAWKLTNSKICLNWEHVKTMENESEVLGYKILYRQNRHSKAHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKISSLSSGGIKLSPRELYTLASGILLLSFVLTYSFP", "length": 1028, "header": "tr|A0A8V0ZEB1-1|A0A8V0ZEB1_CHICK Isoform 1 of Contactin-3 OS=Gallus gallus OX=9031 GN=CNTN6 PE=3 SV=1 CANONICAL=A0A8V0ZEB1-1" }, "locus": { "chromosome": "12", "start_pos": 17828539, "end_pos": 17727466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049386.1", "url": "https://www.ensembl.org/id/ENSGALT00010049386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029193.1", "url": "https://www.ensembl.org/id/ENSGALP00010029193.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427597", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MXS0-1", "protein_name": "Contactin 6", "gene_name": "CNTN6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLLWKLVILMSLINISAGDGGLSPPIFTQEPQDAIFPLDLSKSEIILNCAANGYPLPHYRWKHNGADIDFSMSYHYRLDGGSLAISSPRTDQDIGTYQCLATNSLGTILSQKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPIPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQDTYLSIYDSLFWECKASGKPDPWYTWLKNGERLNLDERIQIENGTLIITMLNVSDSGIYQCAAENKYQIIYANAELRVLASAPDFSKNPLKKYSVVQVGGDIVIECKPNAFPRATISWKRGIESLRQSKRVFLLEDGSLKIYNVTRSDAGLYTCIATNQFGVAKNTGSLIIKERTVITVPPSTMDVTVGESIVLPCQVSRDPSVDVVFVWSFNGDVIDFKKGMAHFERIGGESVGDLMIRNIQLNHSGKYLCTVKTTLESLSADGDIIVRGPPGPPEDVRVKHISSTTCQLSWRPGSDNNSPIQIFSIQARTPFSVGWQAVSTVPEILNGKTFNATVVGLNPWVEYEFRVVAGNSIGIGEPSKPSELLRTKSSVPAVAPTNINGGGGSRSELIITWESIPEELQNGEDFGYIVMLRPVGSTTWTKERVPSVESSRFIYRNENIIPLSPFEIKVGVYNKEGEGPLSTASIIYSGEDEPQLAPRGTSVQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNITTKNITGLKANTVYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGISVLEPSIHFLSVVITIFVVLLFSHLYDE", "length": 1030 }, "evidence": [ { "id": "A0A8V0ZEB1", "url": "https://omabrowser.org/oma/group/A0A8V0ZEB1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P97528-1", "protein_name": "Contactin-6", "gene_name": "Cntn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLWKLVILLPLINSCAGESRFTRPIFIQEPQDVIFPLDLSRSEIILSCTASGYPSPHYRWKQNGTDIDFSMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKSRSTVSVREGQGVVLLCGPPPHFGELSYDWTFNDNPLYVQEDKRRFVSQNTGNLYIAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPMPGKVKYSNSQATLEIPKFQQEDEGFYECVAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGERLNTEERIQTENGTLIITMLNVSDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASISWKRGTENLKQSKRVFFLEDGSLKICNVTRSDAGSYTCVATNQFGNGKSSGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYNATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASIPNVAPVNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMKEKVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTSVQSFSASDMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSVGVQILKPSTQFLTMVGFFYCFVIQPLSR", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZEB1", "url": "https://omabrowser.org/oma/group/A0A8V0ZEB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JMB8-1", "protein_name": "Contactin-6", "gene_name": "Cntn6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLWKLVILLPLINSCAGEGRFSRPIFIQEPQDVIFPLDLSRSEIILTCTANGYPSPHYRWKQNGTDIDFGMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGELSYAWTFNDSPLYVQEDKRRFVSQDTGNLYFAKVEPSDVGNYTCFVTNKEAHRSVQGPPTPLVLRTDGVMGEYEPKIEVRFPETIQAAKDSSIKLECFALGNPVPDISWKRLDGSPMPGKIKYSKSQAILEIPKFQQEDEGFYECIAGNLRGRNLAKGQLIFYAPPEWEQKIQNTYLSIYDSLFWECKASGNPNPSYTWLKNGQRLNTEERIQIENGTLIITMLNISDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIECKPNAFPKASISWKRGTENLKQSKRVLFLEDGSLKICNVTRADAGSYTCVATNQFGNGKSSGGLVVKERTIITVPPSKMDVTVGESIVLPCQVSHDPTMEVLFVWYFNGDIIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTTLERLSAVADIIVRGPPGPPEDVKVEHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGQTYNATVVGLSPWVEYEFRVVAGNNIGIGEPSKPSELLRTKASVPNVAPGNINGGGGSRSELVITWEAIPEELQNGEGFGYIVMFRPVGTTAWMKERVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSVQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKIRVSGNVTTKNITGLRANTIYFASVRAYNTAGTGPSSLPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSTGVQISKPSTQSLSMVGVFYCFAIHPLSR", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZEB1", "url": "https://omabrowser.org/oma/group/A0A8V0ZEB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQ52-1", "protein_name": "Contactin-6", "gene_name": "CNTN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLWKLVILLPLINSSAGDGLLSRPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSEEIRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFHCFAIQPLI", "length": 1028 }, "evidence": [ { "id": "A0A8V0ZEB1", "url": "https://omabrowser.org/oma/group/A0A8V0ZEB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEB1" } ], "pmid": "" }, { "name": "presynaptic 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEG5-1", "uniprot_ac": "A0A8V0ZEG5", "uniprot_id": "A0A8V0ZEG5_CHICK", "mass": { "chemical_mass": 35537.0, "monoisotopic_mass": 35537.0 }, "refseq": { "ac": "XP_015128744", "name": "transcriptional activator protein Pur-beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128744" }, "gene_names": [ { "name": "LOC107049543", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ] }, { "name": "LOC107049543", "type": "synonym", "evidence": [ { "id": "XP_015128744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128744" } ] } ], "protein_names": [ { "name": "Purine rich element binding protein B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5/entry#names_and_taxonomy" } ] }, { "name": "transcriptional activator protein Pur-beta", "type": "synonym", "evidence": [ { "id": "XP_015128744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128744" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015128744.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128744" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107049543", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZEG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "107049543", "url": "https://www.ncbi.nlm.nih.gov/gene/107049543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107049543", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKEDGWS", "url": "https://omabrowser.org/oma/group/AKEDGWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZEG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12611", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12611", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12611:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12611:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADGDSGSERGGSGSGSGGGGGGGFAAPRGGGGGGGGGGGGGPGAGPGPEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDYLGDFIEHYAQLGPSSPEQLAQAAGPGGDEGGSGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGPGGPGGFPGGPPGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEEDELGGPGGGGPGGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPYKAWAKFGGAFCRYADEMRDIQERQRDKLYDRRAGPPGPGSGSGAGDDSDGDDVDDD", "length": 344, "header": "tr|A0A8V0ZEG5-1|A0A8V0ZEG5_CHICK Isoform 1 of Purine rich element binding protein B OS=Gallus gallus OX=9031 GN=LOC107049543 PE=3 SV=1 CANONICAL=A0A8V0ZEG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5/entry#A0A8V0ZEG5-1", "sequence": { "sequence": "MADGDSGSERGGSGSGSGGGGGGGFAAPRGGGGGGGGGGGGGPGAGPGPEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDYLGDFIEHYAQLGPSSPEQLAQAAGPGGDEGGSGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGPGGPGGFPGGPPGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEEDELGGPGGGGPGGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPYKAWAKFGGAFCRYADEMRDIQERQRDKLYDRRAGPPGPGSGSGAGDDSDGDDVDDD", "length": 344, "header": "tr|A0A8V0ZEG5-1|A0A8V0ZEG5_CHICK Isoform 1 of Purine rich element binding protein B OS=Gallus gallus OX=9031 GN=LOC107049543 PE=3 SV=1 CANONICAL=A0A8V0ZEG5-1" }, "locus": { "chromosome": "22", "start_pos": 3316160, "end_pos": 3315129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050141.1", "url": "https://www.ensembl.org/id/ENSGALT00010050141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029627.1", "url": "https://www.ensembl.org/id/ENSGALP00010029627.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049543", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4H2-1", "protein_name": "Purine rich element binding protein B", "gene_name": "PURB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADGDSGSERGGGGGGGPGGFQPASRGGGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDYLGDFIEHYAQLGPSSPEQVAAAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGDESEGEEVDED", "length": 308 }, "evidence": [ { "id": "A0A8V0ZEG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZEG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MCZ1-1", "protein_name": "Purine rich element binding protein B", "gene_name": "PURB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADGDSGSERGGGGPGGFQPASRGGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDYLGDFIEHYAQLGPSSPEQVAAAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGDESEGEEVDED", "length": 304 }, "evidence": [ { "id": "A0A8V0ZEG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZEG5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35295-1", "protein_name": "Transcriptional regulator protein Pur-beta", "gene_name": "Purb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADGDSGSERGGGGGGGGGPGGFQPAPRGGGGGGGGPGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGGGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGDEDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGGGDESEGEEVDED", "length": 324 }, "evidence": [ { "id": "A0A8V0ZEG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZEG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QR8-1", "protein_name": "Transcriptional regulator protein Pur-beta", "gene_name": "PURB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADGDSGSERGGGGGPCGFQPASRGGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGAGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGGGEESEGEEVDED", "length": 312 }, "evidence": [ { "id": "A0A8V0ZEG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZEG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V4D9-1", "protein_name": "Purine-rich binding protein-alpha, isoform B", "gene_name": "Pur-alpha", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDLGSGDDGISGSKYNVANMEGSSSRNDFDSSAKGGSGVEQELATKMLQIQSKRFYLDVKQNRRGRFIKVAEIGADGRRSQIYLALSTAAEFRDHLSSFSDYYASLGPPNTDNLPEDGKLKSEMMIKDYRRYYLDLKENARGRFLRVSQTITRGGPRSQIALPAQGMIEFRDALTDLLEEFGANDGGRFKGDLPEERHMKVDNKNFYFDIGQNNRGVYMRISEVKNNFRTSITIPEKCWIRFRDIFNDYCEKMKKSSDSITAEINLPTSSNSLK", "length": 275 }, "evidence": [ { "id": "A0A8V0ZEG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZEG5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" }, { "name": "purine-rich negative regulatory element binding", "id": "GO:0032422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032422", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEJ0-1", "uniprot_ac": "A0A8V0ZEJ0", "uniprot_id": "A0A8V0ZEJ0_CHICK", "mass": { "chemical_mass": 98398.0, "monoisotopic_mass": 98398.0 }, "refseq": { "ac": "XP_040560784", "name": "dynein axonemal intermediate chain 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560784" }, "gene_names": [ { "name": "WDR63", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0" } ] }, { "name": "WDR63", "type": "synonym", "evidence": [ { "id": "XP_040560784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560784" } ] } ], "protein_names": [ { "name": "Dynein axonemal intermediate chain 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal intermediate chain 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040560784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560784" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560784" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZEJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "429090", "url": "https://www.ncbi.nlm.nih.gov/gene/429090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZEJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040560784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560784", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKNLRSGKTTLKSPKTSAKKQRGEKAKRASKGKQKQPEEKDEVDLSMVGIGHPEIFPLVLTTRTQEIFNCRVDEDVTEENCFKLIKKDDIIQDLKTRAAISDFHPVKNIVLEYPGEELLIVFDANFQYGQNFYLVASEEAKENFLKPPETAEEIDSEEEKEETQDVCAYKPPVSKPWVSLGSEKEVEEESVKDRVKKIKYMFSRGYGKFGAPIRFTDRNASHVKDSYVECTSYQDKTFSIKVLEKDVGVQMVPKVREASTQTEWTYPKNAATQYFPRQLSNEKKEEILSCETLKQFLTSACLRMEIALQQNEIMNAFSDDWKVLEDDISGSGGKSDVCLKAYQIFTDLHYLKDKSISCVCWHPTIYGIIAVSATKLPSKEERTKVQHDSVIIFWSFFDPIHPQLILECPDDIYCFQFSPSNPNIIAGGCFSGQVVLWDISQYEEKLQNAKSVVVGMKKTVNMNNVSVLSLLEDDDMSELLFMEDDESDKGQILVRFCTSSSIHHSHEKKITDIHWLPDYFEVNRMGETFENRAGICVQLVTCSPDSVILFWDIRDTNLPTQHLSEKVKEENSFNMLPDVSNTSNDPDLIWKPLMKISLCDKEEENVKCSPTKISLQEQHYDYKITDKEQALHKSQVLVKESPYAQMSGSSNKTLYVLNNISNNFFVGTEDGEIIYSDWEMKTKSNEEKIGKKYTIHKEAVNTVQRSPFFKDIILSVGGWNFAIWKENVTNGPILQSNCAAQRYTAGHWSLTRPGVFYIATDDGNIDIWDLLKETHKPSHIQNISKSAITCISPWIASSKQQFLAVSDDSGVLHVLEIRRTLSHPSSNEQANILNYFERRVQYLKNHKKDQEFEIKENGN", "length": 860, "header": "tr|A0A8V0ZEJ0-1|A0A8V0ZEJ0_CHICK Isoform 1 of Dynein axonemal intermediate chain 3 OS=Gallus gallus OX=9031 GN=WDR63 PE=4 SV=1 CANONICAL=A0A8V0ZEJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEJ0/entry#A0A8V0ZEJ0-1", "sequence": { "sequence": "MPKNLRSGKTTLKSPKTSAKKQRGEKAKRASKGKQKQPEEKDEVDLSMVGIGHPEIFPLVLTTRTQEIFNCRVDEDVTEENCFKLIKKDDIIQDLKTRAAISDFHPVKNIVLEYPGEELLIVFDANFQYGQNFYLVASEEAKENFLKPPETAEEIDSEEEKEETQDVCAYKPPVSKPWVSLGSEKEVEEESVKDRVKKIKYMFSRGYGKFGAPIRFTDRNASHVKDSYVECTSYQDKTFSIKVLEKDVGVQMVPKVREASTQTEWTYPKNAATQYFPRQLSNEKKEEILSCETLKQFLTSACLRMEIALQQNEIMNAFSDDWKVLEDDISGSGGKSDVCLKAYQIFTDLHYLKDKSISCVCWHPTIYGIIAVSATKLPSKEERTKVQHDSVIIFWSFFDPIHPQLILECPDDIYCFQFSPSNPNIIAGGCFSGQVVLWDISQYEEKLQNAKSVVVGMKKTVNMNNVSVLSLLEDDDMSELLFMEDDESDKGQILVRFCTSSSIHHSHEKKITDIHWLPDYFEVNRMGETFENRAGICVQLVTCSPDSVILFWDIRDTNLPTQHLSEKVKEENSFNMLPDVSNTSNDPDLIWKPLMKISLCDKEEENVKCSPTKISLQEQHYDYKITDKEQALHKSQVLVKESPYAQMSGSSNKTLYVLNNISNNFFVGTEDGEIIYSDWEMKTKSNEEKIGKKYTIHKEAVNTVQRSPFFKDIILSVGGWNFAIWKENVTNGPILQSNCAAQRYTAGHWSLTRPGVFYIATDDGNIDIWDLLKETHKPSHIQNISKSAITCISPWIASSKQQFLAVSDDSGVLHVLEIRRTLSHPSSNEQANILNYFERRVQYLKNHKKDQEFEIKENGN", "length": 860, "header": "tr|A0A8V0ZEJ0-1|A0A8V0ZEJ0_CHICK Isoform 1 of Dynein axonemal intermediate chain 3 OS=Gallus gallus OX=9031 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"MPSLSVTLITTKNIWEHLREKSRHEKLLLQLIWNQLQHVFLTEENYEVKNRAYDYEPCPSSLRAACAAALQLEVQLVSEIKSPSLDSNMATKLPSQEECESWTAFQVADLLRQFGMPESAVLVEKLGMDGSHFLSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 686, "header": "tr|A0A8V0ZEM7-1|A0A8V0ZEM7_CHICK Isoform 1 of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEJ3-1", "sequence": { "sequence": "MLEQSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 556, "header": "tr|A0A8V0ZEJ3-1|A0A8V0ZEM7_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21948522, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052811.1", "url": "https://www.ensembl.org/id/ENSGALT00010052811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031716.1", "url": "https://www.ensembl.org/id/ENSGALP00010031716.1" } ] } }, { "isoform_ac": "A0A8V0ZEL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEL3-1", "sequence": { "sequence": "MATKLPSQEECESWTAFQVADLLRQFGMPESAVLVEKLGMDGSHFLFIRLRAEPIQNNASAIICRGHLRCSISLYSYTDTCASRRKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 621, "header": "tr|A0A8V0ZEL3-1|A0A8V0ZEL3_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21978134, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052825.1", "url": "https://www.ensembl.org/id/ENSGALT00010052825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031731.1", "url": "https://www.ensembl.org/id/ENSGALP00010031731.1" } ] } }, { "isoform_ac": "A0A8V0ZEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEL7-1", "sequence": { "sequence": "MSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 553, "header": "tr|A0A8V0ZEL7-1|A0A8V0ZEL7_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981541, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052830.1", "url": "https://www.ensembl.org/id/ENSGALT00010052830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031736.1", "url": "https://www.ensembl.org/id/ENSGALP00010031736.1" } ] } }, { "isoform_ac": "A0A8V0ZEM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEM2-1", "sequence": { "sequence": "MFGMPESAVLVEKLGMDGSHFLSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 555, "header": "tr|A0A8V0ZEM2-1|A0A8V0ZEM2_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981541, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052835.1", "url": "https://www.ensembl.org/id/ENSGALT00010052835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031741.1", "url": "https://www.ensembl.org/id/ENSGALP00010031741.1" } ] } }, { "isoform_ac": "A0A8V0ZEM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEM7-1", "sequence": { "sequence": "MPSLSVTLITTKNIWEHLREKSRHEKLLLQLIWNQLQHVFLTEENYEVKNRAYDYEPCPSSLRAACAAALQLEVQLVSEIKSPSLDSNMATKLPSQEECESWTAFQVADLLRQFGMPESAVLVEKLGMDGSHFLSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 686, "header": "tr|A0A8V0ZEM7-1|A0A8V0ZEM7_CHICK Isoform 1 of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981698, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052841.1", "url": "https://www.ensembl.org/id/ENSGALT00010052841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031746.1", "url": "https://www.ensembl.org/id/ENSGALP00010031746.1" } ] } }, { "isoform_ac": "A0A8V0ZEN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZEN1-1", "sequence": { "sequence": "MPSLSVTLITTKNIWEHLREKSRHEKLLLQLIWNQLQHVFLTEENYEVKNRAYDYEPCPSSLRAACAAALQLEVQLVSEFGMPESAVLVEKLGMDGSHFLSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 652, "header": "tr|A0A8V0ZEN1-1|A0A8V0ZEN1_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981698, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052845.1", "url": "https://www.ensembl.org/id/ENSGALT00010052845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031751.1", "url": "https://www.ensembl.org/id/ENSGALP00010031751.1" } ] } }, { "isoform_ac": "A0A8V0ZK13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZK13-1", "sequence": { "sequence": "MHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASDNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 537, "header": "tr|A0A8V0ZK13-1|A0A8V0ZK13_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21948292, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052822.1", "url": "https://www.ensembl.org/id/ENSGALT00010052822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031728.1", "url": "https://www.ensembl.org/id/ENSGALP00010031728.1" } ] } }, { "isoform_ac": "A0A8V0ZLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZLS5-1", "sequence": { "sequence": "MPSLSVTLITTKNIWEHLREKSRHEKLLLQLIWNQLQHVFLTEENYEVKNRAYDYEPCPSSLRAACAAALQLEVQLVSESLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 631, "header": "tr|A0A8V0ZLS5-1|A0A8V0ZLS5_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981698, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052854.1", "url": "https://www.ensembl.org/id/ENSGALT00010052854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031760.1", "url": "https://www.ensembl.org/id/ENSGALP00010031760.1" } ] } }, { "isoform_ac": "A0A8V0ZSI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#A0A8V0ZSI0-1", "sequence": { "sequence": "MPSLSVTLITTKNIWEHLREKSRHEKLLLQLIWNQLQHVFLTEENYEVKNRAYDYEPCPSSLRAACAAALQLEVQLVSEFGMPESAVLVEKLGMDGSHFLSLSDYELSRFKIMHQPKLQKMVHDIKKNESGIINKFKKLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 633, "header": "tr|A0A8V0ZSI0-1|A0A8V0ZEM7_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=1 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21981698, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052851.1", "url": "https://www.ensembl.org/id/ENSGALT00010052851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031757.1", "url": "https://www.ensembl.org/id/ENSGALP00010031757.1" } ] } }, { "isoform_ac": "F1NFD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7/entry#F1NFD7-1", "sequence": { "sequence": "MDKLNKLAVPAGEKFRKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPALHCHTARGSSQNGHALPADPHRMPSVLNKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS", "length": 580, "header": "tr|F1NFD7-1|A0A8V0ZEM7_CHICK Computationally mapped isoform of SH2 domain containing 6 OS=Gallus gallus OX=9031 GN=SH2D6 PE=4 SV=4 CANONICAL=A0A8V0ZEM7-1" }, "locus": { "chromosome": "6", "start_pos": 21927706, "end_pos": 21886226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052797.1", "url": "https://www.ensembl.org/id/ENSGALT00010052797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031703.1", "url": "https://www.ensembl.org/id/ENSGALP00010031703.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-983695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983695", "resource": "Reactome", "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEM7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 683, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 292, 369 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 671, "end_pos": 673 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEN6-1", "uniprot_ac": "A0A8V0ZEN6", "uniprot_id": "A0A8V0ZEN6_CHICK", "mass": { "chemical_mass": 68876.0, "monoisotopic_mass": 68876.0 }, "refseq": { "ac": "XP_425698", "name": "matrilin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425698" }, "gene_names": [ { "name": "MATN4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" } ] }, { "name": "MATN4", "type": "synonym", "evidence": [ { "id": "XP_425698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425698" } ] } ], "protein_names": [ { "name": "Matrilin 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6/entry#names_and_taxonomy" } ] }, { "name": "matrilin-4", "type": "synonym", "evidence": [ { "id": "XP_425698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425698.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MATN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6", "locus": { "chromosome": "20", "start_pos": 5511548, "end_pos": 5497736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021742", "url": "https://www.ensembl.org/id/ENSGALG00010021742" } ] } } ], "crossref": [ { "id": "A0A8V0ZEN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "428140", "url": "https://www.ncbi.nlm.nih.gov/gene/428140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428140", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSCSMID", "url": "https://omabrowser.org/oma/group/RSCSMID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZEN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK37", "url": "https://www.orthodb.org/?gene=A0A8V0ZK37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLPLAALLLLILTALEARPKPAALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAHARNAGIEIYAVGIQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCMERDHGCQHSCVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISARGTYSCRCRAGYYLNQDRRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGSFHCVCPEGQQLQADGKTCSKCGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPDGTHVGLVQYSSRVRTEFPLNKYHSAEEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEPVEQHFSYSADFTTMTHLVENFKLNICPEEGRGETEIRSPCECEALVQFQTNTVAILQSLTERIAQMTARLEALEKQIALKK", "length": 621, "header": "tr|A0A8V0ZEN6-1|A0A8V0ZEN6_CHICK Isoform 1 of Matrilin 4 OS=Gallus gallus OX=9031 GN=MATN4 PE=4 SV=1 CANONICAL=A0A8V0ZEN6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6/entry#A0A8V0ZEN6-1", "sequence": { "sequence": "MKLLPLAALLLLILTALEARPKPAALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAHARNAGIEIYAVGIQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCMERDHGCQHSCVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISARGTYSCRCRAGYYLNQDRRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGSFHCVCPEGQQLQADGKTCSKCGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPDGTHVGLVQYSSRVRTEFPLNKYHSAEEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEPVEQHFSYSADFTTMTHLVENFKLNICPEEGRGETEIRSPCECEALVQFQTNTVAILQSLTERIAQMTARLEALEKQIALKK", "length": 621, "header": "tr|A0A8V0ZEN6-1|A0A8V0ZEN6_CHICK Isoform 1 of Matrilin 4 OS=Gallus gallus OX=9031 GN=MATN4 PE=4 SV=1 CANONICAL=A0A8V0ZEN6-1" }, "locus": { "chromosome": "20", "start_pos": 5510812, "end_pos": 5505546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052850.1", "url": "https://www.ensembl.org/id/ENSGALT00010052850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031756.1", "url": "https://www.ensembl.org/id/ENSGALP00010031756.1" } ] } }, { "isoform_ac": "A0A8V0ZK37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6/entry#A0A8V0ZK37-1", "sequence": { "sequence": "MKLLPLAALLLLILTALEARPKPAALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAHARNAGIEIYAVGIQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCMERDHGCQHSCVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISARGTYSCRCRAGYYLNQDRRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGSFHCVCPEGQQLQADGKTCSKCGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPDGTHVGLVQYSSRVRTEFPLNKYHSAEEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEPVEQHFSYSADFTTMTHLVENFKLNICPARSFLSTPTCSDDSQTGSPGEADCPQEVILAAGRRAQRGPTVATWHCY", "length": 615, "header": "tr|A0A8V0ZK37-1|A0A8V0ZK37_CHICK Computationally mapped isoform of Matrilin 4 OS=Gallus gallus OX=9031 GN=MATN4 PE=4 SV=1 CANONICAL=A0A8V0ZEN6-1" }, "locus": { "chromosome": "20", "start_pos": 5510874, "end_pos": 5505546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052847.1", "url": "https://www.ensembl.org/id/ENSGALT00010052847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031753.1", "url": "https://www.ensembl.org/id/ENSGALP00010031753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428140", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZMS3-1", "protein_name": "Matrilin-4", "gene_name": "Matn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGPFCWPLPLLLLFLQSWETQLQPAGPRCYTGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLHSLDVGLNATRVGVIQYSSQVQSVFPLGAFSNREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELEHGCQHLCVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEHLCVSSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFNTMTHLLENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK", "length": 624 }, "evidence": [ { "id": "A0A8V0ZEN6", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SDQ7-1", "protein_name": "Matrilin-4", "gene_name": "MATN4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGLLGLLLPLLLLLLQPWETQLQFAGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLGAFSRREDMEGAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARSRGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGQQFQGRLCRKDLCAEGGHGCQHQCVSAPGTFHCACNPGYRLAADNKSCLAINLCAEETHGCEHHCVSSPGSYFCHCRAGFVLQQDQRSCRAIDYCGFGNHSCQHECVNTFGGPRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLSYRCLCPEGQQLLADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDVSVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECDSLVEFQGRTLGALESLSQNLAQLTARLEELENQLAAQK", "length": 624 }, "evidence": [ { "id": "A0A8V0ZEN6", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O89029-1", "protein_name": "Matrilin-4", "gene_name": "Matn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGPCCWPLSLLLLFLQSWETQLQSAGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRTMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELVHGCQHLCVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEHLCVNSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLAGPQCRCREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK", "length": 624 }, "evidence": [ { "id": "A0A8V0ZEN6", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95460-1", "protein_name": "Matrilin-4", "gene_name": "MATN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK", "length": 622 }, "evidence": [ { "id": "A0A8V0ZEN6", "url": "https://omabrowser.org/oma/group/A0A8V0ZEN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZEN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN6" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 213, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEP8-1", "uniprot_ac": "A0A8V0ZEP8", "uniprot_id": "A0A8V0ZEP8_CHICK", "mass": { "chemical_mass": 58807.0, "monoisotopic_mass": 58807.0 }, "refseq": { "ac": "XP_004943011", "name": "sorting nexin-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943011" }, "gene_names": [ { "name": "SNX4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ] }, { "name": "SNX4", "type": "synonym", "evidence": [ { "id": "XP_004943011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943011" } ] } ], "protein_names": [ { "name": "Sorting nexin 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943011" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943011.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943011" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8", "locus": { "chromosome": "7", "start_pos": 27704412, "end_pos": 27734933, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020437", "url": "https://www.ensembl.org/id/ENSGALG00010020437" } ] } } ], "crossref": [ { "id": "A0A8V0ZEP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07622", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07622", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424260", "url": "https://www.ncbi.nlm.nih.gov/gene/424260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424260", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQKSGHY", "url": "https://omabrowser.org/oma/group/LQKSGHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46596:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46596:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METRGVDQKPLRDAVPGRMDAPEVTLANSREAGAGSQHLTPDGPPCPEQAGLPGAPRPVPCGRARCACRSGLSACAQRGAEPLIAMESAEAEPSESRPEEDGAVPASDLPLPEQPAATMEDCLAKKMEITVSEAEKRTGRNAMNMQETYTAYLIETRAVESQNEGQCSPVDSLWRRYSEFELLRNYLLVTYPHIVVPPLPEKRADFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPVLCQDKIFYSFLTQEGGWKEMVNETGFQLKADSRLKALNATFRVKNPDKRFTELKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYAASIDDILEEEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLTSKKQQCEELATGTVRTFSLKGMTSKLFGQETPEQREAKIKVLEEQIQEGEEQLKSKNLEGRDFVKSAWADIERFKEQKNHDLKEALISYAVMQISMCKKGIQVWTNAKECFGKM", "length": 520, "header": "tr|A0A8V0ZEP8-1|A0A8V0ZEP8_CHICK Isoform 1 of Sorting nexin 4 OS=Gallus gallus OX=9031 GN=SNX4 PE=1 SV=1 CANONICAL=A0A8V0ZEP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8/entry#A0A8V0ZEP8-1", "sequence": { "sequence": "METRGVDQKPLRDAVPGRMDAPEVTLANSREAGAGSQHLTPDGPPCPEQAGLPGAPRPVPCGRARCACRSGLSACAQRGAEPLIAMESAEAEPSESRPEEDGAVPASDLPLPEQPAATMEDCLAKKMEITVSEAEKRTGRNAMNMQETYTAYLIETRAVESQNEGQCSPVDSLWRRYSEFELLRNYLLVTYPHIVVPPLPEKRADFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPVLCQDKIFYSFLTQEGGWKEMVNETGFQLKADSRLKALNATFRVKNPDKRFTELKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYAASIDDILEEEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLTSKKQQCEELATGTVRTFSLKGMTSKLFGQETPEQREAKIKVLEEQIQEGEEQLKSKNLEGRDFVKSAWADIERFKEQKNHDLKEALISYAVMQISMCKKGIQVWTNAKECFGKM", "length": 520, "header": "tr|A0A8V0ZEP8-1|A0A8V0ZEP8_CHICK Isoform 1 of Sorting nexin 4 OS=Gallus gallus OX=9031 GN=SNX4 PE=1 SV=1 CANONICAL=A0A8V0ZEP8-1" }, "locus": { "chromosome": "7", "start_pos": 27734903, "end_pos": 27706236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049406.1", "url": "https://www.ensembl.org/id/ENSGALT00010049406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029202.1", "url": "https://www.ensembl.org/id/ENSGALP00010029202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424260", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AAD8-1", "protein_name": "Sorting nexin-4", "gene_name": "Snx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERVPPDPEKLLQPAPLEPLGGPGAVLEAAVGEETEGTREDVSGADTMTGNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHADGQSVLTDSLWRRYSEFELLRNYLLVYYPHVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPVLCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTELRQYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLETAAQDLASKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKVASPGIYCVSKFVPVYNLCLKVCTTT", "length": 461 }, "evidence": [ { "id": "A0A8V0ZEP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZEP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A4L0-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEQAAPDPERLWQPAPLEPLSHPDAGLESMVGEETKGARDEGPGDGTMTENNFSLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHNDGQSVLTDSLWRRYSEFELLRNYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFIELKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKMLEEQIKEGEQQLKSKNLEGREFVRNAWADIERFKEQKNHDLKEALISYAVMQISMCKKGIQVWTNAKECFSKM", "length": 450 }, "evidence": [ { "id": "A0A8V0ZEP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZEP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFSKM", "length": 450 }, "evidence": [ { "id": "A0A8V0ZEP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZEP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47057-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": 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"MEQAPPDPEKLLQPGPLEPLGGPGAVLEAAVGEENEGTREDGSGVDTMTGNNFWLKKIEISVSEAEKRTGRNAVNMQETYTAYLIETRSVEHADGQSVLTDSLWRRYSEFELLRNYLLVYYPHVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRVGLENFLLRVASHPVLCRDKIFYSFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTELRHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLETAAQDLAAKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFSKM", "length": 450 }, "evidence": [ { "id": "A0A8V0ZEP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZEP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ], "pmid": "" }, { "name": "epidermal 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"" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ], "pmid": "" }, { "name": "presynaptic endosome", "id": "GO:0098830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP8" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP8", "url": 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"id": "ENSGALP00010029742.1", "url": "https://www.ensembl.org/id/ENSGALP00010029742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZER3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZER3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER3" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM222A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9", "locus": { "chromosome": "15", "start_pos": 6851755, "end_pos": 6828406, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021764", "url": "https://www.ensembl.org/id/ENSGALG00010021764" } ] } } ], "crossref": [ { "id": "A0A8V0ZET9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZET9", "database": "AlphaFoldDB", "categories": [] }, { "id": "768548", "url": "https://www.ncbi.nlm.nih.gov/gene/768548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QQHLRMY", "url": "https://omabrowser.org/oma/group/QQHLRMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZET9", "url": "https://www.orthodb.org/?gene=A0A8V0ZET9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZEU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK97", "url": "https://www.orthodb.org/?gene=A0A8V0ZK97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM78", "url": "https://www.orthodb.org/?gene=A0A8V0ZM78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZSN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZET9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGCHAPQAVPVGGWGPRRCRPPPAVSATRRWPLHHPSWGHDHHRNRCTSKGGKQQNPTGKEGRRVAGAVPVQLGQGSVPTCPHVSPQCQHGATGIHKALSTGTWDPSIGGLCVCQHSPRCVCFLPSVVQIFRFLKSAGSFAEREGDCWSTLGALKMLRLPHYVGAEHLIPKLGETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 569, "header": "tr|A0A8V0ZET9-1|A0A8V0ZET9_CHICK Isoform 1 of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZET9-1", "sequence": { "sequence": "MPRGCHAPQAVPVGGWGPRRCRPPPAVSATRRWPLHHPSWGHDHHRNRCTSKGGKQQNPTGKEGRRVAGAVPVQLGQGSVPTCPHVSPQCQHGATGIHKALSTGTWDPSIGGLCVCQHSPRCVCFLPSVVQIFRFLKSAGSFAEREGDCWSTLGALKMLRLPHYVGAEHLIPKLGETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 569, "header": "tr|A0A8V0ZET9-1|A0A8V0ZET9_CHICK Isoform 1 of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6845560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052907.1", "url": "https://www.ensembl.org/id/ENSGALT00010052907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031813.1", "url": "https://www.ensembl.org/id/ENSGALP00010031813.1" } ] } }, { "isoform_ac": "A0A8V0ZEU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZEU5-1", "sequence": { "sequence": "MPTLRLEKTTKFIKSSCQPITTVPTHPRCAAPSQRCPLSHCCLHHPHPPPYPHPPPPPMAAWMSRSPVQHAQRSPWGAEGAAPHAPTFGTTSPRAQLQEEEGGENCQRPAECRAGCLCLTGDGGASGEFASRSNYSPLESSNYSGEGEPLTSSAHERARSLLEIGETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 559, "header": "tr|A0A8V0ZEU5-1|A0A8V0ZEU5_CHICK Computationally mapped isoform of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6847116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052912.1", "url": "https://www.ensembl.org/id/ENSGALT00010052912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031818.1", "url": "https://www.ensembl.org/id/ENSGALP00010031818.1" } ] } }, { "isoform_ac": "A0A8V0ZK97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZK97-1", "sequence": { "sequence": "MHADFAQQWVRVHGQTPPAPLLITVSLLLAVHGAAAAGQDSQTMLACLQRTQNPPGQHLACPNPNKALEPRKCETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 467, "header": "tr|A0A8V0ZK97-1|A0A8V0ZK97_CHICK Computationally mapped isoform of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6839606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052909.1", "url": "https://www.ensembl.org/id/ENSGALT00010052909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031815.1", "url": "https://www.ensembl.org/id/ENSGALP00010031815.1" } ] } }, { "isoform_ac": "A0A8V0ZLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZLY0-1", "sequence": { "sequence": "MLRLPHYVGAEHLIPKLGETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 412, "header": "tr|A0A8V0ZLY0-1|A0A8V0ZLY0_CHICK Computationally mapped isoform of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6846031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052911.1", "url": "https://www.ensembl.org/id/ENSGALT00010052911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031817.1", "url": "https://www.ensembl.org/id/ENSGALP00010031817.1" } ] } }, { "isoform_ac": "A0A8V0ZM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZM78-1", "sequence": { "sequence": "MKVHGAAAAGQDSQTMLACLQRTQNPPGQHLACPNPNKALEPRKCETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 439, "header": "tr|A0A8V0ZM78-1|A0A8V0ZM78_CHICK Computationally mapped isoform of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6829773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052910.1", "url": "https://www.ensembl.org/id/ENSGALT00010052910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031816.1", "url": "https://www.ensembl.org/id/ENSGALP00010031816.1" } ] } }, { "isoform_ac": "A0A8V0ZSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET9/entry#A0A8V0ZSN1-1", "sequence": { "sequence": "MAFGQLGVHGAAAAGQDSQTMLACLQRTQNPPGQHLACPNPNKALEPRKCETAAPMHSPRYPSPAELDAYAQKVANSPLTIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPVHAGGYQGLLAIVKASSKSVVKNAEGKRTKLSPAQAGVAPYPSSSTLAPGPSCAGPLSYHQKQLEGPVPPNVTVAGSALPLAGRGLALPPSNLPSIQSIIYQLNQQCQAQASQPACPALPAAHPSPAKHGTFPTMASAYAVLPECRKGAELPLGSTPALGPKAGLYPDGVDYLLWQQKQQQHLRVYSGGSGALSKSPEACAAASRPYGPAGEKVSSSPLNCMHGNFAVGQYFVPPWNSVLVTPTSDCYNPPPELGPVPRELGVPPAEGLPSKALCNTSILSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 444, "header": "tr|A0A8V0ZSN1-1|A0A8V0ZET9_CHICK Computationally mapped isoform of Family with sequence similarity 222 member A OS=Gallus gallus OX=9031 GN=FAM222A PE=4 SV=1 CANONICAL=A0A8V0ZET9-1" }, "locus": { "chromosome": "15", "start_pos": 6850670, "end_pos": 6838966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052908.1", "url": "https://www.ensembl.org/id/ENSGALT00010052908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031814.1", "url": "https://www.ensembl.org/id/ENSGALP00010031814.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MTD2-1", "protein_name": "Family with sequence similarity 222 member A", "gene_name": "FAM222A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLACLQRTQNAPGQHLACPTKSLELRKCETVASSMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGYDTSGQRYSPYPPHTAGYQGLLAIVKAAVSSSSSAAAPAGPAKSVLKSAEGKRTKLSPAAVQVGVAPYPAPSTLGPLAYPKPPEVPAPPPGLPAAAAPAAAVIPLPGRGLPLPPSNLPSIHSLLYQLHQQCQAPGAAPAACQAVPGPPPSPAKHGPVPGFPRTAYSATAGPPECRKGAELGQGSTPAALTLAGAAKPAGYADGGLDYLLWPQKPPPPPPPPPQPLRAYGGGALASKSPEACGGRAYERASGSPLNCGVGLPASFTVGQYFAAPWNSVLVTPTSDCYNPAAAAAAAAAAAAAAGTELGPGAARELAGPPAETLSGLPSKSVCNTAVLSSSLQSLEYLINDIRPPCIKERMLGKGYETVAVPRLLDHQHAHIRLPVYR", "length": 467 }, "evidence": [ { "id": "A0A8V0ZET9", "url": "https://omabrowser.org/oma/group/A0A8V0ZET9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M2BCF5-1", "protein_name": "Protein FAM222A", "gene_name": "fam222aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLACLQRRQNPAPQHNPAVCSSSSSKSLEPTQHINRKCELTVPMPSPRYPSAAELDAYAQKTASSPLSIKIFPTNIRVPQHKHLNRTVNGYDTTGQRYSPYPHLHTGGYQGLLAIVKVSSSSSSSCSSFVPSAKGVLKNSEGRRTKLSPAQIAVAPYPPPNSSTLGHCHGQIVYHTGPPKPPEATTLSVPPNVTVAGSVIPVAGGRGLNLPPQSNLPSIQSIIYQINQHCQAQALQQVCQNGTSTGPPNPSPSKQGTTNSSGGTYVTGVAPQGNMPYSGTVIPGQNGEVLKAGVYPEGMDYLLWQKQQHHHQQQQAVLRMYSGGSGGGGAISKSPETCGPVGSIMLGGAQVSSSRGYPMTASTSGGGGLEKVSSSPLNCVGMHGNFSVGQYFAPPWNSVLVTPDSDCYNPQELPGATTTAGPVTGHRELGFPHHHQHPHHHHHHHHQHHHHHHPPIDSTGGLCCSLPSKSLCNTSVLSSSLQSLEYLINDIHPPCIKEQMLGKGYETVSVPRLLDHQHAHIRLPVYR", "length": 527 }, "evidence": [ { "id": "A0A8V0ZET9", "url": "https://omabrowser.org/oma/group/A0A8V0ZET9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZY38-1", "protein_name": "Family with sequence similarity 222, member A", "gene_name": "Fam222a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLACLQRTQNPPGQHLTCPSKSLELRKCESVASSMPSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGYDTSGQRYNPYPQHTTGYQGLLAIVKAAVSSTAATPAGHTKSVLKSVEGKRTKLSPATVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPNLPAAATATSVIPLPGRGLPLPPSNLPSIHSILYQLNQQCQAPGVAPSACQGVAVPHPSPAKHGPVPSFPRVAYSATAGLPDCRKGTELSQGATPALTLAGATKPAGYSEGGLDYLLWPQKPPPPPPQPLRAYGSSSTVASKSPETCSGRAFERANGSPHNCGMGLPGGFTVGQYFAAPWNSVLVTPTSDCYNAAAAAVVTELGPGAARELAGPPVDTLSGLTSKSVCNTAVLSSSLQSLEYLINDIRPPCIKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR", "length": 452 }, "evidence": [ { "id": "A0A8V0ZET9", "url": "https://omabrowser.org/oma/group/A0A8V0ZET9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RIT4-1", "protein_name": "Family with sequence similarity 222 member A", "gene_name": "FAM222A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLACLQRTQNAPGQHLACPTKSLELRKCETVGSSMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGYDTSGQRYSPYPQHTAGYQGLLAIVKAAVSSSGAAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPAPSTLGPLAYPKPPEVPAPPPGLPAAAATAASVIPLPGRGLPLPPSNLPSIHSILYQLNQQCQAPGAAPAACQAVAVPHPSPAKHGPMPSFPSMAYSATAGLPDCRKGTELGQGSTPALTLAGATKPAGYAEGGLDYLLWPQKPPPPPPQPLRAYSGGAVASKSPESCAGRVYERASGSPLNCGVGLPASFTVGQYFATPWNSVLVTPTSDCYNPAAAAVAVTELGPGAARELAGPPAETLSGLPSKSVCNTAVLSSSLQSLEYLINDIRPPCIKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR", "length": 454 }, "evidence": [ { "id": "A0A8V0ZET9", "url": "https://omabrowser.org/oma/group/A0A8V0ZET9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HI78-1", "protein_name": "Protein FAM222A", "gene_name": "Fam222a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"MLACLQRTQNPPGQHLACPSKSLDLRKCESVASSMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGYDTSGQRYSPYPQHTAGYQGLLAIVKAAVSSSAHAPAGHPKSVLKSVEGKRTKLSPATVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPSLPAAATATSVIPLPGRGLPLPPSNLPSIHSILYQLNQQCQAPGAAPSACQGVAVPHPSPAKHGPVPSFPNLAYSATAGLPDCRKGTELSQGATPALTLAGATKPAGYAEGGLDYLLWPQKPPPPPPQPLRAYSSSTVAGKSQSPEICGGRAFERANGSPHNCGMGLPGSFTVGQYFAAPWNSVLVTPTSDCYNPAAAAVVTELAPGAARELAGPPGDVLSGLTSKSVCNTAVLSSSLQSLEYLINDIRPPCIKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR", "length": 453 }, "evidence": [ { "id": "A0A8V0ZET9", "url": "https://omabrowser.org/oma/group/A0A8V0ZET9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 395 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEV1-1", "uniprot_ac": "A0A8V0ZEV1", "uniprot_id": "A0A8V0ZEV1_CHICK", "mass": { "chemical_mass": 46990.0, "monoisotopic_mass": 46990.0 }, "refseq": { "ac": "XP_004941726", "name": "acyl-coenzyme A thioesterase 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941726" }, "gene_names": [ { "name": "ACOT6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1" } ] }, { "name": "ACOT6", "type": "synonym", "evidence": [ { "id": "XP_004941726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941726" } ] } ], "protein_names": [ { "name": "Acyl-CoA thioesterase 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1/entry#names_and_taxonomy" } ] }, { "name": "acyl-coenzyme A thioesterase 5", "type": "synonym", "evidence": [ { "id": "XP_004941726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941726" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941726.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941726" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACOT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZEV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "423247", "url": "https://www.ncbi.nlm.nih.gov/gene/423247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423247", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEKPYQR", "url": "https://omabrowser.org/oma/group/IEKPYQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRAAVAAKAPARALCRAPARRAVSVAVTPAAGLADERVDTRVAGLGPGQPVTLRAVVSDERGCLFQSCAHYRADGRGELHLGTDASHGGNYTGVEPMGLFWSLAPAGMERPYQRLVPRSTGTPMKVEMLVHQGHSQPGAIHGPVMAKAEVERWFTAPGVRRIRLKEGGVRGSLFLPPGDGPFPGVIDMYGDEGGLIEFRSSLLATRGFAALSLPYFDFEDLPKVMKEFKLEYFQEAARFLQRHPKVKGPGVGVIGTGKGAELALSMITFLPEVVAAVCISGCSSNTVADLHYGEITLPGLRFDMNKVSVSDTGVFDTFEALDDPANPANSSCTIPIEKAEGHFLLVVGEADRMWKSSLYAELAIGRLRQHGKENFELLSYPGAGHRIDPPSTPFCQVALDRVLGVPVLGGGESKAHAHAQEHSWGKIQEFLHLHLG", "length": 437, "header": "tr|A0A8V0ZEV1-1|A0A8V0ZEV1_CHICK Isoform 1 of Acyl-CoA thioesterase 6 OS=Gallus gallus OX=9031 GN=ACOT6 PE=1 SV=1 CANONICAL=A0A8V0ZEV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1/entry#A0A8V0ZEV1-1", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"https://www.ensembl.org/id/ENSGALP00010029829.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-GGA-9854311", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9854311", "resource": "Reactome", "description": "Maturation of TCA enzymes and regulation of TCA cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZEZ7-1", "uniprot_ac": "A0A8V0ZEZ7", "uniprot_id": "A0A8V0ZEZ7_CHICK", "mass": { "chemical_mass": 22856.0, "monoisotopic_mass": 22856.0 }, "refseq": { "ac": "XP_046777727", "name": "fas apoptotic inhibitory molecule 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777727" }, "gene_names": [ { "name": "FAIM", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ] }, { "name": "FAIM", "type": "synonym", "evidence": [ { "id": "XP_046777727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777727" } ] } ], "protein_names": [ { "name": "Fas apoptotic inhibitory molecule 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZEZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7/entry#names_and_taxonomy" } ] }, { "name": "fas apoptotic inhibitory molecule 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046777727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777727" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052579.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046777727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777727" } ] }, { "annotation": "Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7#function" }, { "database": "UniProtKB", "id": "ARBA00058770", "url": "https://www.uniprot.org/uniprotkb/ARBA00058770#function" }, { "database": "UniProtKB", "id": "A0A8V0ZF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF77#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAIM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7", "locus": { "chromosome": "7", "start_pos": 27884787, "end_pos": 27893319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020614", "url": "https://www.ensembl.org/id/ENSGALG00010020614" } ] } } ], "crossref": [ { "id": "A0A8V0ZEZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZEZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "424270", "url": "https://www.ncbi.nlm.nih.gov/gene/424270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQEYRIM", "url": "https://omabrowser.org/oma/group/SQEYRIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZEZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF77", "url": "https://www.orthodb.org/?gene=A0A8V0ZF77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13088:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13088:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046777727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777727", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASREEVTLSEEEVRSRYSHLEKMTDLVAVWEVALSDGVHKIEFEHGTTSGKRVVYVDGKEIIRKEWMFKLVGKETFTVGVSKTRATINIDAVSGFAYEYTLEINGKSLKKYMENRSKTTNTWVLSLGGTDYRVVLEKDTMDVWCNGEKMETAGEFVEDGTETHFSVGDHSCYIKAVSSGKRKEGIIHTLIVDDREIPEAVE", "length": 202, "header": "tr|A0A8V0ZEZ7-1|A0A8V0ZEZ7_CHICK Isoform 1 of Fas apoptotic inhibitory molecule 1 OS=Gallus gallus OX=9031 GN=FAIM PE=3 SV=1 CANONICAL=A0A8V0ZEZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7/entry#A0A8V0ZEZ7-1", "sequence": { "sequence": "MASREEVTLSEEEVRSRYSHLEKMTDLVAVWEVALSDGVHKIEFEHGTTSGKRVVYVDGKEIIRKEWMFKLVGKETFTVGVSKTRATINIDAVSGFAYEYTLEINGKSLKKYMENRSKTTNTWVLSLGGTDYRVVLEKDTMDVWCNGEKMETAGEFVEDGTETHFSVGDHSCYIKAVSSGKRKEGIIHTLIVDDREIPEAVE", "length": 202, "header": "tr|A0A8V0ZEZ7-1|A0A8V0ZEZ7_CHICK Isoform 1 of Fas apoptotic inhibitory molecule 1 OS=Gallus gallus OX=9031 GN=FAIM PE=3 SV=1 CANONICAL=A0A8V0ZEZ7-1" }, "locus": { "chromosome": "7", "start_pos": 27892800, "end_pos": 27888929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049754.1", "url": "https://www.ensembl.org/id/ENSGALT00010049754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029399.1", "url": "https://www.ensembl.org/id/ENSGALP00010029399.1" } ] } }, { "isoform_ac": "A0A8V0ZF77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7/entry#A0A8V0ZF77-1", "sequence": { "sequence": "MENDVCITANKSISHKSIHSQHSLLLSCFSSFLAAGWIKSPLVTMASREEVTLSEEEVRSRYSHLEKMTDLVAVWEVALSDGVHKIEFEHGTTSGKRVVYVDGKEIIRKEWMFKLVGKETFTVGVSKTRATINIDAVSGFAYEYTLEINGKSLKKYMENRSKTTNTWVLSLGGTDYRVVLEKDTMDVWCNGEKMETAGEFVEDGTETHFSVGDHSCYIKAVSSGKRKEGIIHTLIVDDREIPEAVE", "length": 246, "header": "tr|A0A8V0ZF77-1|A0A8V0ZF77_CHICK Computationally mapped isoform of Fas apoptotic inhibitory molecule 1 OS=Gallus gallus OX=9031 GN=FAIM PE=3 SV=1 CANONICAL=A0A8V0ZEZ7-1" }, "locus": { "chromosome": "7", "start_pos": 27892932, "end_pos": 27888929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049753.1", "url": "https://www.ensembl.org/id/ENSGALT00010049753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029398.1", "url": "https://www.ensembl.org/id/ENSGALP00010029398.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HNW2-1", 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"go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:1902042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF03-1", "uniprot_ac": "A0A8V0ZF03", "uniprot_id": "A0A8V0ZF03_CHICK", "mass": { "chemical_mass": 33036.0, "monoisotopic_mass": 33036.0 }, "refseq": {}, "gene_names": [ { "name": "DGUOK", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ] } ], "protein_names": [ { "name": "Deoxyguanosine kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DGUOK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03", "locus": { "chromosome": "22", "start_pos": 3106183, "end_pos": 3104629, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020617", "url": "https://www.ensembl.org/id/ENSGALG00010020617" } ] } } ], "crossref": [ { "id": "A0A8V0ZF03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF03", "url": "https://www.orthodb.org/?gene=A0A8V0ZF03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10513:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10513:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-74217", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74217", 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} ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "purine deoxyribonucleoside metabolic process", "id": "GO:0046122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "pmid": "" }, { "name": "dAMP salvage", "id": "GO:0106383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF03" }, { "id": "PF01712", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01712" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deoxynucleoside kinase", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 281, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF08-1", "uniprot_ac": "A0A8V0ZF08", "uniprot_id": "A0A8V0ZF08_CHICK", "mass": { "chemical_mass": 205003.0, "monoisotopic_mass": 205003.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08", "locus": {} } ], "crossref": [ { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12300", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12300", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054596", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054596", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZF08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPRPGSFPLLVRGDWGTAEPPAALRKKLLLYFQSPKRSGGGECELRWEAGRLLVCFAQPDVKQQVLERQTHELDLGEKGKFKITVTDLEAAAEQEAFGKQLVPTEALDAMRDLQRKGGALQKMENDFPNSELQERARSMERTAEQSAETSPSVVLENTEGCSAKCIQILLENVSGLSADDDFTVEMIPELNVAVATFQKSIDTQELINKCAQNKRVKRFKITARLLEVTRSIKAENIPDDISIDYLRVYFESTRNGGGPVSDIQLFPVENSAIITFCDHKDLSTVLEKQHLLEQTPVSVHPYYHSLGTALYGEDRPVTKMPDSVVIPLDPYVWQFLRRQARLIEAINQEMANCHCYLKWPQTDCSQPEITLCPSSSISEQKGTMIKLIKTWKQDVSTEFSRIMLRYISIKCKVSSAKWKDVKNRLMKNADLIITDISEEMVVIAGNRAAVDSAEKEVRECMEKAMEESKREKQNIEIPVSITPGRYAVLRNAGLEENIHKEYPHLKISYDDTKETVQLCGLSAEVYKVKANLLEKVLNMPSTSVDVNHNVLLYLRCANSKTMSEKLFAAKKINAFYELEDDTVILFGETPKDLSEGEKQLKASLACKSIDVKDCEVTKMKEWSHLLDALRKKYPSSQKTVVIQEPIGYGNTVTITGFTETVEEVCQNLYDFIDRNTWVERKIPTKLVAAVQFVEKEKSAVCDELRKKGVTICFHTKTPYISLSGPRAEVPKAATVLEKIILSLYWKEVSIDKPGAKEIFIDRKNTLIFEAKQKFNCLIRLKEEEQQKSKNVDKVERKLYYKLTLEDGTELLVYKGNLCNYPVDVVVNAASEDLRHTDGFAWALLQAAGPELQAECDEVVRMTGSLQAGDAVITGAGKLPCKQVIHAVGPQWKEKNSGKCMYLLMEAIKKSLQLAETYNHRSIAFPSVSGGIFGFPPHKCVNAIVSAIKKTLEEFKRDSSLKEIHLVAVDEETVRVLRETVQKEFTAKSSSSVLQQQCSPNHRQGESQREKRGDDLFMATGGENMITTAEGLRIQVEKKDIIDATTDVIVNSVGTDLKFGVGPLCRALLKEAGPELQMEFDKEKGQQVAGNGSVVCTKGYILDCTFVFHAVLPQWDRGSGQALKTLENTVHKCLMKAEEFGLKSIAFPAIGTGGFSFPHTVVSKLMFDEVFKFSRCQSRKTLQEVHFVLHPNDRQNIQAFTSELKCRVTGKYCGAAPQPDFISPVSIEASGAYTMRIGSVTLKVTSGDITKEDTEVIVNIANQTFDATSGVFKAIMDAAGFDVKEECNQYGGLLQSGFITTKGGALLCRRIIHLIHSMNVKNQVSEVLHECQLRTYKSVAFPAIGTGAAQQSPAKVADDMLDAIVEFVSSRSVPHLKEIRIIIFQKHMLRDFLQSMKKREDPGLFEPPQSRMSTPKSCFWGPKKSIEKKKLLALEKKVDTVTFQICGESQKNVDATESWIIDVILKEQLENRIVDDVIENFDERQTEALADLQRGKHVTIKLEKNHSPPCITISGINRDVCSVFVEVQKMIQKKKAAQEEQNKAELIYKLVGWKYQKSDDSFVAFDKLTNMQLEDARLCKKPHLTVKINKTIYKVDLNTLQAHDDQGRTINIQREPKNGDMQSIENPAKWEAMQGEQVKLVTLARSCQEYLEVQKLFQKTAHNFVIEQIQRIQNPFLWQSYQIKKKSLCMKNKNQDNEKLLFHGTAKSSLSTINYNGFNRGFAGMHAASIGKGTYFAVDAIYSAEDTYSRPDMSGRKYMYLVRVLTGEFCVGSRELVAAPPKHSADPTDLYDSVVDDVNAPNMFVIFNDIQAYPEYLITFRR", "length": 1823, "header": "tr|A0A8V0ZF08-1|A0A8V0ZF08_CHICK Isoform 1 of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZF08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08/entry#A0A8V0ZF08-1", "sequence": { "sequence": "MAGPRPGSFPLLVRGDWGTAEPPAALRKKLLLYFQSPKRSGGGECELRWEAGRLLVCFAQPDVKQQVLERQTHELDLGEKGKFKITVTDLEAAAEQEAFGKQLVPTEALDAMRDLQRKGGALQKMENDFPNSELQERARSMERTAEQSAETSPSVVLENTEGCSAKCIQILLENVSGLSADDDFTVEMIPELNVAVATFQKSIDTQELINKCAQNKRVKRFKITARLLEVTRSIKAENIPDDISIDYLRVYFESTRNGGGPVSDIQLFPVENSAIITFCDHKDLSTVLEKQHLLEQTPVSVHPYYHSLGTALYGEDRPVTKMPDSVVIPLDPYVWQFLRRQARLIEAINQEMANCHCYLKWPQTDCSQPEITLCPSSSISEQKGTMIKLIKTWKQDVSTEFSRIMLRYISIKCKVSSAKWKDVKNRLMKNADLIITDISEEMVVIAGNRAAVDSAEKEVRECMEKAMEESKREKQNIEIPVSITPGRYAVLRNAGLEENIHKEYPHLKISYDDTKETVQLCGLSAEVYKVKANLLEKVLNMPSTSVDVNHNVLLYLRCANSKTMSEKLFAAKKINAFYELEDDTVILFGETPKDLSEGEKQLKASLACKSIDVKDCEVTKMKEWSHLLDALRKKYPSSQKTVVIQEPIGYGNTVTITGFTETVEEVCQNLYDFIDRNTWVERKIPTKLVAAVQFVEKEKSAVCDELRKKGVTICFHTKTPYISLSGPRAEVPKAATVLEKIILSLYWKEVSIDKPGAKEIFIDRKNTLIFEAKQKFNCLIRLKEEEQQKSKNVDKVERKLYYKLTLEDGTELLVYKGNLCNYPVDVVVNAASEDLRHTDGFAWALLQAAGPELQAECDEVVRMTGSLQAGDAVITGAGKLPCKQVIHAVGPQWKEKNSGKCMYLLMEAIKKSLQLAETYNHRSIAFPSVSGGIFGFPPHKCVNAIVSAIKKTLEEFKRDSSLKEIHLVAVDEETVRVLRETVQKEFTAKSSSSVLQQQCSPNHRQGESQREKRGDDLFMATGGENMITTAEGLRIQVEKKDIIDATTDVIVNSVGTDLKFGVGPLCRALLKEAGPELQMEFDKEKGQQVAGNGSVVCTKGYILDCTFVFHAVLPQWDRGSGQALKTLENTVHKCLMKAEEFGLKSIAFPAIGTGGFSFPHTVVSKLMFDEVFKFSRCQSRKTLQEVHFVLHPNDRQNIQAFTSELKCRVTGKYCGAAPQPDFISPVSIEASGAYTMRIGSVTLKVTSGDITKEDTEVIVNIANQTFDATSGVFKAIMDAAGFDVKEECNQYGGLLQSGFITTKGGALLCRRIIHLIHSMNVKNQVSEVLHECQLRTYKSVAFPAIGTGAAQQSPAKVADDMLDAIVEFVSSRSVPHLKEIRIIIFQKHMLRDFLQSMKKREDPGLFEPPQSRMSTPKSCFWGPKKSIEKKKLLALEKKVDTVTFQICGESQKNVDATESWIIDVILKEQLENRIVDDVIENFDERQTEALADLQRGKHVTIKLEKNHSPPCITISGINRDVCSVFVEVQKMIQKKKAAQEEQNKAELIYKLVGWKYQKSDDSFVAFDKLTNMQLEDARLCKKPHLTVKINKTIYKVDLNTLQAHDDQGRTINIQREPKNGDMQSIENPAKWEAMQGEQVKLVTLARSCQEYLEVQKLFQKTAHNFVIEQIQRIQNPFLWQSYQIKKKSLCMKNKNQDNEKLLFHGTAKSSLSTINYNGFNRGFAGMHAASIGKGTYFAVDAIYSAEDTYSRPDMSGRKYMYLVRVLTGEFCVGSRELVAAPPKHSADPTDLYDSVVDDVNAPNMFVIFNDIQAYPEYLITFRR", "length": 1823, "header": "tr|A0A8V0ZF08-1|A0A8V0ZF08_CHICK Isoform 1 of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZF08-1" }, "locus": { "chromosome": "7", "start_pos": 27853181, "end_pos": 27836739, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049635.1", "url": "https://www.ensembl.org/id/ENSGALT00010049635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029322.1", "url": "https://www.ensembl.org/id/ENSGALP00010029322.1" } ] } }, { "isoform_ac": "A0A8V0ZL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08/entry#A0A8V0ZL21-1", "sequence": { "sequence": "MSPRQDHRVKMSVLKEGVRSEDAVGTGPAPGGALQKMENDFPNSELQERARSMERTAEQSAETSPSVVLENTEGCSAKCIQILLENVSGLSADDDFTVEMIPELNVAVATFQKSIDTQELINKCAQNKRVKRFKITARLLEVTRSIKAENIPDDISIDYLRVYFESTRNGGGPVSDIQLFPVENSAIITFCDHKDLSTVLEKQHLLEQTPVSVHPYYHSLGTALYGEDRPVTKMPDSVVIPLDPYVWQFLRRQARLIEAINQEMANCHCYLKWPQTDCSQPEITLCPSSSISEQKGTMIKLIKTWKQDVSTEFSRIMLRYISIKCKVSSAKWKDVKNRLMKNADLIITDISEEMVVIAGNRAAVDSAEKEVRECMEKAMEESKREKQNIEIPVSITPGRYAVLRNAGLEENIHKEYPHLKISYDDTKETVQLCGLSAEVYKVKANLLEKVLNMPSTSVDVNHNVLLYLRCANSKTMSEKLFAAKKINAFYELEDDTVILFGETPKDLSEGEKQLKASLACKSIDVKDCEVTKMKEWSHLLDALRKKYPSSQKTVVIQEPIGYGNTVTITGFTETVEEVCQNLYDFIDRNTWVERKIPTKLVAAVQFVEKEKSAVCDELRKKGVTICFHTKTPYISLSGPRAEVPKAATVLEKIILSLYWKEVSIDKPGAKEIFIDRKNTLIFEAKQKFNCLIRLKEEEQQKSKNVDKVERKLYYKLTLEDGTELLVYKGNLCNYPVDVVVNAASEDLRHTDGFAWALLQAAGPELQAECDEVVRMTGSLQAGDAVITGAGKLPCKQVIHAVGPQWKEKNSGKCMYLLMEAIKKSLQLAETYNHRSIAFPSVSGGIFGFPPHKCVNAIVSAIKKTLEEFKRDSSLKEIHLVAVDEETVRVLRETVQKEFTAKSSSSVLQQQCSPNHRQGESQREKRGDDLFMATGGENMITTAEGLRIQVEKKDIIDATTDVIVNSVGTDLKFGVGPLCRALLKEAGPELQMEFDKEKGQQVAGNGSVVCTKGYILDCTFVFHAVLPQWDRGSGQALKTLENTVHKCLMKAEEFGLKSIAFPAIGTGGFSFPHTVVSKLMFDEVFKFSRCQSRKTLQEVHFVLHPNDRQNIQAFTSELKCRVTGKYCGAAPQPDFISPVSIEASGAYTMRIGSVTLKVTSGDITKEDTEVIVNIANQTFDATSGVFKAIMDAAGFDVKEECNQYGGLLQSGFITTKGGALLCRRIIHLIHSMNVKNQVSEVLHECQLRTYKSVAFPAIGTGAAQQSPAKVADDMLDAIVEFVSSRSVPHLKEIRIIIFQKHMLRDFLQSMKKREDPGLFEPPQSRMSTPKSCFWGPKKSIEKKKLLALEKKVDTVTFQICGESQKNVDATESWIIDVILKEQLENRIVDDVIENFDERQTEALADLQRGKHVTIKLEKNHSPPCITISGINRDVCSVFVEVQKMIQKKKAAQEEQNKAELIYKLVGWKYQKSDDSFVAFDKLTNMQLEDARLCKKPHLTVKINKTIYKVDLNTLQAHDDQGRTINIQREPKNGDMQSIENPAKWEAMQGEQVKLVTLARSCQEYLEVQKLFQKTAHNFVIEQIQRIQNPFLWQSYQIKKKSLCMKNKNQDNEKLLFHGTAKSSLSTINYNGFNRGFAGMHAASIGKGTYFAVDAIYSAEDTYSRPDMSGRKYMYLVRVLTGEFCVGSRELVAAPPKHSADPTDLYDSVVDDVNAPNMFVIFNDIQAYPEYLITFRR", "length": 1735, "header": "tr|A0A8V0ZL21-1|A0A8V0ZL21_CHICK Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZF08-1" }, "locus": { "chromosome": "7", "start_pos": 27850409, "end_pos": 27836739, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049632.1", "url": "https://www.ensembl.org/id/ENSGALT00010049632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029320.1", "url": "https://www.ensembl.org/id/ENSGALP00010029320.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 484, "start_aa": "Thr", "end_pos": 484, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr484", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", 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"length": 1690, "header": "tr|A0A8V0ZF17-1|A0A8V0ZF17_CHICK Isoform 1 of Vitellogenin 3 OS=Gallus gallus OX=9031 GN=VTG3 PE=1 SV=1 CANONICAL=A0A8V0ZF17-1" }, "locus": { "chromosome": "8", "start_pos": 16275128, "end_pos": 16254253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050572.1", "url": "https://www.ensembl.org/id/ENSGALT00010050572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029854.1", "url": "https://www.ensembl.org/id/ENSGALP00010029854.1" } ] } }, { "isoform_ac": "A0A8V0ZG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17/entry#A0A8V0ZG90-1", "sequence": { "sequence": "MIAVCFSQAFKFEYTEGRVGSIYAPENCPILCINLVRGVLNMMQITIKKTQNVYELQEAGIEGICQARYVIQDDSKNNRATISKSKDLTDCQDSAVQSTGMAYIRPCPTCPMKVKNMKGTVLFTYKMKYYGSGALMTSAMSEQVYQISPFNEPDGVAAMEARQELVLLDIKSTPIKAPDTQLQNQGSLRYHFPEGLLQMPIPLIRVKNAGVQLAETLRQLGQNNEEGRTTEASIKFLQMVQLLRVVTLDQIESVWVQFASEQPYRHWFLSAVCAAGATDTFQFLKQKIHDKNLNIWEAAVALPLAFHSVMPNKKTLEVASTFLTCPQIQKAPMLRVLVYLGYGSLVNKYCAQPSFCPNELLQPLHDLAAEASSRSHVEDMALALKAIGNAGEPASIKRILKFLPTFSLAAAALPSRIHTDAVLSLRKIARKDPAKVRGIALQIFMDSTLAPNVRMTACIVLFETKPSLPIVVAMASSLLTETSLQVTSFMYSHMKALAVGRIPQLYNLSAACNIAIKLLSPRLDKLSYRYSKVVHAGGYSHVYKAGAIWRVYLMNSPNTVFPSDIITKVRGYYANTATDIVEMALRSQSLTSVIRKQNIPFAEYDTYKTLKELGKKLLGWKELPPEDPLLSAYIKVLGQEIAFVDIDNGIIQQAMKSLTGSSSWQPAVKRAVEEAQRGVSGQWALPAVVAELRHTVPMVLGLPLELSVCGAALAQAAAAVDIQMSPPLPDNFRPSKLLETNMDIHADIKPKVYIHMIAMMGTNTQYLQSGLELHAEFSANTTMKFDARINMKEKNVKIETLPCHQEVELAAVRSEAYAISRNTEEVDTEKKSPILPKGEMPTISNQRFQSSEIFSRARSWKQRNIPSVMSKEHLQGSEEEHHHGVGQRSYAHVFCRKLASLGCSACLSLKSRNSPFLRNTCLNNLVGELEAKIVLKPVHTDADIEKIQLEIQAGAKAASKIIDATSSGPKEEKKPSLYENIKAKLKKILGIENVFKVANKTRHHKKWIHSRVKAAVTDLWEEPSATPLSSSSSTDSSAEGEEPGNKRDKDEIWQFGKKYGADSSSSSSSSTGSGSSKTCSSSREDSSRDKHCSVDSEYFNQQADLPIYQFWFKPADEQDPRRKVQNSSISSSSSSSSDEGISTPVSQPMFLGDSKPPVLAAVLRAIRRNEQPTGYQLVLYTDRQASRLRVQVFVSSITESDRWKLCADASVVNSHKASGTLKWGKDCQDYQVATQIATGQFAAHPAIQVKLEWSEVPSSVRKTARWFYTYLPGAAYMLGYSQKQQHGPSHQAAMVMALTSPRTCDVVLKLPELTVYNRAIRLPLPLPSSSDTPTSTLPSSKWNVFYQAAFSIIENLKARCSVSQNMITTFNGVEFNYSMPANCYHILAQDCSPELKFLVMMKRLGESADLTAISVRLASHEVDMYVSNGLIQLKINGVQTPTDVPYTSKSGLLISSEKEGLSLKAPEYGVEKLYYDRRKLEIRVAFWMVGKTCGICGKYDAEKKREYQMPSGYLAKDAVSFAQSWVISEDTCTGACKLQRKFVKIEKPVAFNKKASKCFSIEPVLRCAEGCSATRTVPVSVGFHCVPSDSTLELEEEQVRLDQKSEDLVSRVDAHTACSCAQQLCSA", "length": 1627, "header": "tr|A0A8V0ZG90-1|A0A8V0ZG90_CHICK Computationally mapped isoform of Vitellogenin 3 OS=Gallus gallus OX=9031 GN=VTG3 PE=1 SV=1 CANONICAL=A0A8V0ZF17-1" }, "locus": { "chromosome": "8", "start_pos": 16275128, "end_pos": 16256074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050556.1", "url": "https://www.ensembl.org/id/ENSGALT00010050556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029846.1", "url": "https://www.ensembl.org/id/ENSGALP00010029846.1" } ] } }, { "isoform_ac": "A0A8V0ZGA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17/entry#A0A8V0ZGA0-1", "sequence": { "sequence": "MRGFILALVLALVGISVIYFSIEPVFSTGKTYLYDYKGHILHGLPGKGLAAAGLKLTCRLEIIRVSRSDHLLQIRSPKLEEYHGFWPRDPFTPSPKLTEMIAVCFSQAFKFEYTEGRVGSIYAPENCPILCINLVRGVLNMMQITIKKTQNVYELQEAGIEGICQARYVIQDDSKNNRATISKSKDLTDCQDSAVQSTGMAYIRPCPTCPMKVKNMKGTVLFTYKMKYYGSGALMTSAMSEQVYQISPFNEPDGVAAMEARQELVLLDIKSTPIKAPDTQLQNQGSLRYHFPEGLLQMPIPLIRVKNAGVQLAETLRQLGQNNEEGRTTEASIKFLQMVQLLRVVTLDQIESVWVQFASEQPHWFLSAVCAAGATDTFQFLKQKIHDKNLNIWEAAVALPLAFHSVMPNKKTLEVASTFLTCPQIQKAPMLRVLVYLGYGSLVNKYCAQPSFCPNELLQPLHDLAAEASSRSHVEDMALALKAIGNAGEPASIKRILKFLPTFSLAAAALPSRIHTDAVLSLRKIARKDPAKVRGIALQIFMDSTLAPNVRMTACIVLFETKPSLPIVVAMASSLLTETSLQVTSFMYSHMKALAVGRIPQLYNLSAACNIAIKLLSPRLDKLSYRYSKVVHAGGYSHVYKAGAIWRVYLMNSPNTVFPSDIITKVRGYYANTATDIVEMALRSQSLTSVIRKQNIPFAEYDTYKTLKELGKKLLGWKELPPEDPLLSAYIKVLGQEIAFVDIDNGIIQQAMKVVTRLLAVEEAQRGVSGQWALPAVVAELRHTVPMVLGLPLELSVCGAALAQAAAAVDIQMSPPLPDNFRPSKLLETNMDIHADIKPKVYIHMIAMMGTNTQYLQSGLELHAEFSANTTMKFDARINMKEKNVKIETLPCHQEVELAAVRSEAYAISRNTEEVDTEKKSPILPKGEMPTISNQRFQSSEIFSRARSWKVTGPVLQAGREQTASQSPRESLQGSAEAHSLKLASLGCSACLSLKSRNSPFLRNTCLNNLVGELEAKIVLKPVHTDADIEKIQLEIQAGAKAASKIIDATSSGPKEEKKPSLYENIKAKLKKILGIENVFKVANKTRHHKKWIHSRVKAAVTDLWEEPSATPLSSSSSTDSSAEGEEPGNKRDKDEIWQFGKKYGADSSSSSSSSTGSGSSKTCSSSREDSSRDKHCSVDSEYFNQQVINSDWIFYIYVVNVFLPEIRKLYSKPPVLAAVLRAIRRNEQPTGYQLVLYTDRQASRLRVQVFVSSITESDRWKLCADASVVNSHKASGTLKWGKDCQDYQVATQIATGQFAAHPAIQVKLEWSEVPSSVRKTARWFYTYLPGAAYMLGYSQKQQHGPSHQAAMVMALTSPRTCDVVLKLPELTVYNRAIRLPLPLPSSSDTPTSTLPSSKWNVFYQAAFSIIENLKARCSVSQNMITTFNGVEFNYSMPANCYHILAQDCSPELKFLVMMKRLGESADLTAISVRLANISFFSFVAGLLISSEKEGLSLKAPEYGVEKLYYDRRKLEIRVAFWMVGKTCGICGKYDAEKKREYQMPSGYLAKDAVSFAQSWVISEDTCTGACKLQRKFVKIEKPVAFNKKASKCFSIEPVLRCAEGCSATRTVPVSVGFHCVPSDSTLELEEEQVRLDQKSEDLVSRVDAHTACSCAQQLCSA", "length": 1662, "header": "tr|A0A8V0ZGA0-1|A0A8V0ZGA0_CHICK Computationally mapped isoform of Vitellogenin 3 OS=Gallus gallus OX=9031 GN=VTG3 PE=1 SV=1 CANONICAL=A0A8V0ZF17-1" }, "locus": { "chromosome": "8", "start_pos": 16275128, "end_pos": 16254253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050576.1", "url": "https://www.ensembl.org/id/ENSGALT00010050576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029856.1", "url": "https://www.ensembl.org/id/ENSGALP00010029856.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" } ], "pmid": "" }, { "name": "nutrient reservoir activity", "id": "GO:0045735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to estradiol", "id": "GO:0032355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1439, "end_pos": 1441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 870, "end_pos": 872, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 1421, "end_pos": 1596, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZF17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF17" }, { "id": "PS51211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vitellogenin", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 664, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1089, "end_pos": 1091 }, { "start_pos": 1439, "end_pos": 1441 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 870, "end_pos": 872 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF25-1", "uniprot_ac": "A0A8V0ZF25", "uniprot_id": "A0A8V0ZF25_CHICK", "mass": { "chemical_mass": 36643.0, "monoisotopic_mass": 36643.0 }, "refseq": { "ac": "XP_040545153", "name": "aflatoxin B1 aldehyde reductase member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545153" }, "gene_names": [ { "name": "AKR7A2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25" } ] }, { "name": "AKR7A2", "type": "synonym", "evidence": [ { "id": "XP_040545153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545153" } ] } ], "protein_names": [ { "name": "Aldo-keto reductase family 7 member A2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25/entry#names_and_taxonomy" } ] }, { "name": "aflatoxin B1 aldehyde reductase member 2", "type": "synonym", "evidence": [ { "id": "XP_040545153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545153" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052593.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040545153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKR7A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZF25", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF25", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419471", "url": "https://www.ncbi.nlm.nih.gov/gene/419471", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419471", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419471", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYWHGDL", "url": "https://omabrowser.org/oma/group/NYWHGDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF25", "url": "https://www.orthodb.org/?gene=A0A8V0ZF25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43364:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43364:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5423646", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423646", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040545153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGARPGVVLGAMEMGRRAGPEASSAMLRAFLRRGHRLLDTAYMYAGGESERILGTLLAGGEHSVEVATKANPWEGNTLKPDSVRSQLNTSLERLQRTSVELFYLHAPDHGTPVEETLRACNELHKEGKFKELGLSNYAAWEVAEICTICKCNNWLMPTVYQGMYNATTRQVELELFPCLRYYGLRFYAYNPLAGGLLTGKYKYEDKDTRQPTGRFFGNDWAQAYRDRYWKKHNFEGIELVKKALKDAYGSNAPSLTSAALRWLYHHSKLQGSLGDAVIVGMSNMEQLEQNLNYSEEGPLLPPVVEALDEAWKLTAHDCPNYFR", "length": 326, "header": "tr|A0A8V0ZF25-1|A0A8V0ZF25_CHICK Isoform 1 of Aldo-keto reductase family 7 member A2 OS=Gallus gallus OX=9031 GN=AKR7A2 PE=1 SV=1 CANONICAL=A0A8V0ZF25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25/entry#A0A8V0ZF25-1", "sequence": { "sequence": "MAAGGARPGVVLGAMEMGRRAGPEASSAMLRAFLRRGHRLLDTAYMYAGGESERILGTLLAGGEHSVEVATKANPWEGNTLKPDSVRSQLNTSLERLQRTSVELFYLHAPDHGTPVEETLRACNELHKEGKFKELGLSNYAAWEVAEICTICKCNNWLMPTVYQGMYNATTRQVELELFPCLRYYGLRFYAYNPLAGGLLTGKYKYEDKDTRQPTGRFFGNDWAQAYRDRYWKKHNFEGIELVKKALKDAYGSNAPSLTSAALRWLYHHSKLQGSLGDAVIVGMSNMEQLEQNLNYSEEGPLLPPVVEALDEAWKLTAHDCPNYFR", "length": 326, "header": "tr|A0A8V0ZF25-1|A0A8V0ZF25_CHICK Isoform 1 of Aldo-keto reductase family 7 member A2 OS=Gallus gallus OX=9031 GN=AKR7A2 PE=1 SV=1 CANONICAL=A0A8V0ZF25-1" }, "locus": { "chromosome": "21", "start_pos": 4670496, "end_pos": 4666869, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049667.1", "url": "https://www.ensembl.org/id/ENSGALT00010049667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029342.1", "url": "https://www.ensembl.org/id/ENSGALP00010029342.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419471", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419471", "resource": "KEGG Pathway" }, { "id": "R-GGA-5423646", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423646", "resource": "Reactome", "description": "Aflatoxin activation and detoxification" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alcohol dehydrogenase (NADP+) activity", "id": "GO:0008106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008106", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF25" }, { "id": "PF00248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADP-dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 314, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF42-1", "uniprot_ac": "A0A8V0ZF42", "uniprot_id": "A0A8V0ZF42_CHICK", "mass": { "chemical_mass": 45525.0, "monoisotopic_mass": 45525.0 }, "refseq": {}, "gene_names": [ { "name": "CTBS", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42" } ] } ], "protein_names": [ { "name": "Di-N-acetylchitobiase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Reducing-end exoglycosidase involved in glycan degradation. Hydrolyzes N,N'-diacetylchitobiose (GlnNAc2) and higher chitin-oligosaccharides (GlcNAc(n)) to monomeric GlcNAc acting on reducing-end residues. During N-linked glycoprotein degradation, it cleaves single GlcNAc molecules uniquely from the reducing end of N,N'-diacetylchitobiose units linking oligosaccharides to proteins, and therefore it functions after cleavage of the Asn-GlcNAc bond and asparagine removal by glycosylasparaginase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42#function" }, { "database": "UniProtKB", "id": "ARBA00094420", "url": "https://www.uniprot.org/uniprotkb/ARBA00094420#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGH1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTBS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42", "locus": { "chromosome": "8", "start_pos": 16281990, "end_pos": 16275146, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020946", "url": "https://www.ensembl.org/id/ENSGALG00010020946" } ] } } ], "crossref": [ { "id": "A0A8V0ZF42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02875", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF42", "url": "https://www.orthodb.org/?gene=A0A8V0ZF42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46290:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46290:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "30671", "url": "https://www.rhea-db.org/rhea/30671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84983", "url": "https://www.rhea-db.org/rhea/84983", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85195", "url": "https://www.rhea-db.org/rhea/85195", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85199", "url": "https://www.rhea-db.org/rhea/85199", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85203", "url": "https://www.rhea-db.org/rhea/85203", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85207", "url": "https://www.rhea-db.org/rhea/85207", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85211", "url": "https://www.rhea-db.org/rhea/85211", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZF42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVTSFCTRTALIRSRRPGPLLRGGAASPGPPRPPAPPAEAEVAAGSDMGCPGCAGLVLLLGLLQLLGRTAACPCQDPRLCQPIAGTDRFEVFVFDVGKEAWKSYDWSKITTVAAFGKYDPELLCFAHSKGARVVLKGDVPLKEVVDPAKRAAWISQQVDLAKKQYMDGINIDIEQEVNETSPEYYALTELVKETTDAFHKEIPGSQVTFDVAWSPACIDKRCYNYTGIAAACDFLFVMSYDEQSQIWTDCIAKANAPYLQTLFGYEEYITMGIDPKKLVMGVPWYGYDYVCLNLSEDHVCSLPKVPFRGAPCSDAAGHQVPYGEIMKQVNSSISGALWDEVQNSPFYEYKDSLGHFHQVWYDDPRSISLKAAYVKNRGLKGIGMWNGNSLDYSREAVAEEQTEAMWQALTP", "length": 412, "header": "tr|A0A8V0ZF42-1|A0A8V0ZF42_CHICK Isoform 1 of Di-N-acetylchitobiase OS=Gallus gallus OX=9031 GN=CTBS PE=1 SV=1 CANONICAL=A0A8V0ZF42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42/entry#A0A8V0ZF42-1", "sequence": { "sequence": "MDVTSFCTRTALIRSRRPGPLLRGGAASPGPPRPPAPPAEAEVAAGSDMGCPGCAGLVLLLGLLQLLGRTAACPCQDPRLCQPIAGTDRFEVFVFDVGKEAWKSYDWSKITTVAAFGKYDPELLCFAHSKGARVVLKGDVPLKEVVDPAKRAAWISQQVDLAKKQYMDGINIDIEQEVNETSPEYYALTELVKETTDAFHKEIPGSQVTFDVAWSPACIDKRCYNYTGIAAACDFLFVMSYDEQSQIWTDCIAKANAPYLQTLFGYEEYITMGIDPKKLVMGVPWYGYDYVCLNLSEDHVCSLPKVPFRGAPCSDAAGHQVPYGEIMKQVNSSISGALWDEVQNSPFYEYKDSLGHFHQVWYDDPRSISLKAAYVKNRGLKGIGMWNGNSLDYSREAVAEEQTEAMWQALTP", "length": 412, "header": "tr|A0A8V0ZF42-1|A0A8V0ZF42_CHICK Isoform 1 of Di-N-acetylchitobiase OS=Gallus gallus OX=9031 GN=CTBS PE=1 SV=1 CANONICAL=A0A8V0ZF42-1" }, "locus": { "chromosome": "8", "start_pos": 16280981, "end_pos": 16275345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050615.1", "url": "https://www.ensembl.org/id/ENSGALT00010050615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029880.1", "url": "https://www.ensembl.org/id/ENSGALP00010029880.1" } ] } }, { "isoform_ac": "A0A8V0ZGH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF42/entry#A0A8V0ZGH1-1", "sequence": { "sequence": "MGCPGCAGLVLLLGLLQLLGRTAACPCQDPRLCQPIAGTDRFEPSCLGDVPLKEVVDPAKRAAWISQQVDLAKKQYMDGINIDIEQEVNETSPEYYALTELVKETTDAFHKEIPGSQVTFDVAWSPACIDKRCYNYTGIAAACDFLFVMSYDEQSQIWTDCIAKANAPYLQTLFGYEEYITMGIDPKKLVMGVPWYGYDYVCLNLSEDHVCSLPKVPFRGAPCSDAAGHQVPYGEIMKQVNSSISGALWDEVQNSPFYEYKDSLGHFHQVWYDDPRSISLKAAYVKNRGLKGIGMWNGNSLDYSREAVAEEQTEAMWQALTP", "length": 322, "header": "tr|A0A8V0ZGH1-1|A0A8V0ZGH1_CHICK Computationally mapped isoform of Di-N-acetylchitobiase OS=Gallus gallus OX=9031 GN=CTBS PE=1 SV=1 CANONICAL=A0A8V0ZF42-1" }, "locus": { "chromosome": "8", "start_pos": 16280981, "end_pos": 16275489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050608.1", "url": "https://www.ensembl.org/id/ENSGALT00010050608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029876.1", "url": "https://www.ensembl.org/id/ENSGALP00010029876.1" } ] } } ], "glycosylation": [], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF49-1", "uniprot_ac": "A0A8V0ZF49", "uniprot_id": "A0A8V0ZF49_CHICK", "mass": { "chemical_mass": 45394.0, "monoisotopic_mass": 45394.0 }, "refseq": {}, "gene_names": [ { "name": "KLHDC8B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ] } ], "protein_names": [ { "name": "Kelch domain-containing protein 8B", 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Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49#function" }, { "database": "UniProtKB", "id": "ARBA00045748", "url": "https://www.uniprot.org/uniprotkb/ARBA00045748#function" }, { "database": "UniProtKB", "id": "A0A8V0ZM86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM86#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHDC8B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49", "locus": { "chromosome": "12", "start_pos": 11710292, "end_pos": 11715818, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021792", "url": "https://www.ensembl.org/id/ENSGALG00010021792" } ] } } ], "crossref": [ { "id": "A0A8V0ZF49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF49", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF49", "url": "https://www.orthodb.org/?gene=A0A8V0ZF49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM86", "url": "https://www.orthodb.org/?gene=A0A8V0ZM86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMK0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46260:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTGSPGEREHRRVWEMSREARERMPHGDEQSHGKQEPGGSRVNSHHCRGPDGWHGGAWAWGPPGWLSHPMAASSAGVFTWVSFPSMPTRRVYCSAVHHDGQLFVLGGCGGSGRALGAAEVLDLQAQCWTALPPLPTPRAGAATLAVGKQILAVGGVDASQSPLASVEIYHVDEGRWEKKAALAQPSMGIAAVQRDGAVYVLGGMGADTSPQALVRVYEPAKDHWQPLPSMPTPCYGASAFLQGNKIFVLGGRQGKLPVTAFEAFDLETKSWTRYPSVPSRRAFASCAMADSIFFSLGGLQQPGPHNFYSRPHFVNTVEMFDPVQGAWCKPSRAIRMREKRADFVAGCLGGYVVAMGGLGNQSCPLDSVEGFSLTRRRWELLPPMPTGRCSCSSCPAPDLLFVIGGVDQGPSGAVEALCLRDAP", "length": 424, "header": "tr|A0A8V0ZF49-1|A0A8V0ZF49_CHICK Isoform 1 of Kelch domain-containing protein 8B OS=Gallus gallus OX=9031 GN=KLHDC8B PE=4 SV=1 CANONICAL=A0A8V0ZF49-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49/entry#A0A8V0ZF49-1", "sequence": { "sequence": "MCTGSPGEREHRRVWEMSREARERMPHGDEQSHGKQEPGGSRVNSHHCRGPDGWHGGAWAWGPPGWLSHPMAASSAGVFTWVSFPSMPTRRVYCSAVHHDGQLFVLGGCGGSGRALGAAEVLDLQAQCWTALPPLPTPRAGAATLAVGKQILAVGGVDASQSPLASVEIYHVDEGRWEKKAALAQPSMGIAAVQRDGAVYVLGGMGADTSPQALVRVYEPAKDHWQPLPSMPTPCYGASAFLQGNKIFVLGGRQGKLPVTAFEAFDLETKSWTRYPSVPSRRAFASCAMADSIFFSLGGLQQPGPHNFYSRPHFVNTVEMFDPVQGAWCKPSRAIRMREKRADFVAGCLGGYVVAMGGLGNQSCPLDSVEGFSLTRRRWELLPPMPTGRCSCSSCPAPDLLFVIGGVDQGPSGAVEALCLRDAP", "length": 424, "header": "tr|A0A8V0ZF49-1|A0A8V0ZF49_CHICK Isoform 1 of Kelch domain-containing protein 8B OS=Gallus gallus OX=9031 GN=KLHDC8B PE=4 SV=1 CANONICAL=A0A8V0ZF49-1" }, "locus": { "chromosome": "12", "start_pos": 11714805, "end_pos": 11712341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053014.1", "url": "https://www.ensembl.org/id/ENSGALT00010053014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031920.1", "url": "https://www.ensembl.org/id/ENSGALP00010031920.1" } ] } }, { "isoform_ac": "A0A8V0ZM86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49/entry#A0A8V0ZM86-1", "sequence": { "sequence": "MAASSAGVFTWVSFPSMPTRRVYCSAVHHDGQLFVLGGCGGSGRALGAAEVLDLQAQCWTALPPLPTPRAGAATLAVGKQILAVGGVDASQSPLASVEIYHVDEGRWEKKAALAQPSMGIAAVQRDGAVYVLGGMGADTSPQALVRVYEPAKDHWQPLPSMPTPCYGASAFLQGNKIFVLGGRQGKLPVTAFEAFDLETKSWTRYPSVPSRRAFASCAMADSIFFSLGGLQQPGPHNFYSRPHFVNTVEMFDPVQGAWCKPSRAIRMREKRADFVAGCLGGYVVAMGGLESQPNEGKRASKTRAKNVWGWMEKSSGKKAKQMMALTVLKTDTLLSEELM", "length": 339, "header": "tr|A0A8V0ZM86-1|A0A8V0ZM86_CHICK Computationally mapped isoform of Kelch domain-containing protein 8B OS=Gallus gallus OX=9031 GN=KLHDC8B PE=4 SV=1 CANONICAL=A0A8V0ZF49-1" }, "locus": { "chromosome": "12", "start_pos": 11714374, "end_pos": 11710585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053018.1", "url": "https://www.ensembl.org/id/ENSGALT00010053018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031924.1", "url": "https://www.ensembl.org/id/ENSGALP00010031924.1" } ] } }, { "isoform_ac": "A0A8V0ZMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49/entry#A0A8V0ZMK0-1", "sequence": { "sequence": "MRAGLGPRHSERGYPPASFLLHVKSWEPGGSRVNSHHCRGPDGWHGGAWAWGPPGWLSHPMAASSAGVFTWVSFPSMPTRRVYCSAVHHDGQLFVLGGCGGSGRALGAAEVLDLQAQCWTALPPLPTPRAGAATLAVGKQILAVGGVDASQSPLASVEIYHVDEGRWEKKAALAQPSMGIAAVQRDGAVYVLGGMGADTSPQALVRVYEPAKDHWQPLPSMPTPCYGASAFLQGNKIFVLALASHPHAGGRQGKLPVTAFEAFDLETKSWTRYPSVPSRRAFASCAMADSIFFSLGGLQQPGPHNFYSRPHFVNTVEMFDPVQGAWCKPSRAIRMREKRADFVAGCLGGYVVAMGGLGNQSCPLDSVEGFSLTRRRWELLPPMPTGRCSCSSCPAPDLLFVIGGVDQGPSGAVEALCLRDAP", "length": 422, "header": "tr|A0A8V0ZMK0-1|A0A8V0ZMK0_CHICK Computationally mapped isoform of Kelch domain-containing protein 8B OS=Gallus gallus OX=9031 GN=KLHDC8B PE=4 SV=1 CANONICAL=A0A8V0ZF49-1" }, "locus": { "chromosome": "12", "start_pos": 11715754, "end_pos": 11712341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053017.1", "url": "https://www.ensembl.org/id/ENSGALT00010053017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031923.1", "url": "https://www.ensembl.org/id/ENSGALP00010031923.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 137, "start_aa": "Thr", "end_pos": 137, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr137", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "cellularization cleavage furrow", "id": "GO:0110070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic cytokinetic process", "id": "GO:1902410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "mitotic nuclear division", "id": "GO:0140014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "nuclear chromosome segregation", "id": "GO:0098813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "uniprot_canonical_ac": "A0A8V0ZF59-1", "uniprot_ac": "A0A8V0ZF59", "uniprot_id": "A0A8V0ZF59_CHICK", "mass": { "chemical_mass": 106491.0, "monoisotopic_mass": 106491.0 }, "refseq": { "ac": "NP_001006399", "name": "integrator complex subunit 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399" }, "gene_names": [ { "name": "INTS7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59" } ] }, { "name": "INTS7", "type": "synonym", "evidence": [ { "id": "NP_001006399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59/entry#names_and_taxonomy" } ] }, { "name": "int7", "type": "synonym", "evidence": [ { "id": "NP_001006399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399" } ] }, { "name": "integrator complex subunit 7", "type": "synonym", "evidence": [ { "id": "NP_001006399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719843.1, SRR13267658.23928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001006399.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59", "locus": { "chromosome": "3", "start_pos": 21771201, "end_pos": 21738435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020590", "url": "https://www.ensembl.org/id/ENSGALG00010020590" } ] } } ], "crossref": [ { "id": "A0A8V0ZF59", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF59", "database": "AlphaFoldDB", "categories": [] }, { "id": "421374", "url": "https://www.ncbi.nlm.nih.gov/gene/421374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421374", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GITWCTG", "url": "https://omabrowser.org/oma/group/GITWCTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF59", "url": "https://www.orthodb.org/?gene=A0A8V0ZF59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13322:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13322:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSMASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAANFSAQSKDFAAGICNKISEMIQGLATPVDLKLKLIPILQHMHHDASLASSSRQLLQQLVTSYPSTKMVIVTLHTFTLLAASSLVDIPKQVQLLLQYLKNDPRKAVKRLAIQDLKLLANKMPHTWSRENIQALCESALHTPYDSLKLGMLSVLSTLSGTIAIKQYFSSAPGTAATTARSFDLVKLAQECCYHNNRGIAAHGVRILTNISASCQEKDLLPLEQDAVFGLESLLVLCSQDDSPGAQATLKITLTCMVKLVKCRPHLSQSVVESLLTQLHSAQDAARILMCHCLAAIAMQLPVLADGMLGDLMELYKVIGRSTTDKKQELLVSLATVIFVSSQKALSPEIKTVIKQQLENASNGWTAYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEDNYSSALSCIAEALKSYHKGIASLTAASTPLNPLSFQCGFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTSGNDLQRCGRISNQMKLSMEEFRNLAVRYGDLYQSSFDADSATLRNVELQQQSCLLISHAIEALILDPESANFQEYSSNGAAHVESEYERRMMSVFNHVLEEVESLNRKYAPVSYLHTACLCSAVIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSVLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFVILGTHNITVESSVIDSNGIVWKTGPKTTIFVKSLEDPYSQQVRLQQQQGQPPSQQQQQRTAYSRF", "length": 961, "header": "tr|A0A8V0ZF59-1|A0A8V0ZF59_CHICK Isoform 1 of Integrator complex subunit 7 OS=Gallus gallus OX=9031 GN=INTS7 PE=3 SV=1 CANONICAL=A0A8V0ZF59-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF59/entry#A0A8V0ZF59-1", "sequence": { "sequence": "MAAGGKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSMASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAANFSAQSKDFAAGICNKISEMIQGLATPVDLKLKLIPILQHMHHDASLASSSRQLLQQLVTSYPSTKMVIVTLHTFTLLAASSLVDIPKQVQLLLQYLKNDPRKAVKRLAIQDLKLLANKMPHTWSRENIQALCESALHTPYDSLKLGMLSVLSTLSGTIAIKQYFSSAPGTAATTARSFDLVKLAQECCYHNNRGIAAHGVRILTNISASCQEKDLLPLEQDAVFGLESLLVLCSQDDSPGAQATLKITLTCMVKLVKCRPHLSQSVVESLLTQLHSAQDAARILMCHCLAAIAMQLPVLADGMLGDLMELYKVIGRSTTDKKQELLVSLATVIFVSSQKALSPEIKTVIKQQLENASNGWTAYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEDNYSSALSCIAEALKSYHKGIASLTAASTPLNPLSFQCGFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTSGNDLQRCGRISNQMKLSMEEFRNLAVRYGDLYQSSFDADSATLRNVELQQQSCLLISHAIEALILDPESANFQEYSSNGAAHVESEYERRMMSVFNHVLEEVESLNRKYAPVSYLHTACLCSAVIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSVLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFVILGTHNITVESSVIDSNGIVWKTGPKTTIFVKSLEDPYSQQVRLQQQQGQPPSQQQQQRTAYSRF", "length": 961, "header": "tr|A0A8V0ZF59-1|A0A8V0ZF59_CHICK Isoform 1 of Integrator complex subunit 7 OS=Gallus gallus OX=9031 GN=INTS7 PE=3 SV=1 CANONICAL=A0A8V0ZF59-1" }, "locus": { "chromosome": "3", "start_pos": 21758612, "end_pos": 21738463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049718.1", "url": "https://www.ensembl.org/id/ENSGALT00010049718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029377.1", "url": "https://www.ensembl.org/id/ENSGALP00010029377.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421374", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADS6-1", "protein_name": "Integrator complex subunit 7", "gene_name": "Ints7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKSDPRKAVKRLAVQDLKLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVAPGNVGSSPRSSDLVKLAQECCYHSNRAIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLESLLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSSQDAARILMCHCLAAIAMKLPVLGDGMLGDLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEGSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHADSEYERRMMSVYSHVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRRIQSVCLNVSSTLQSKSSQDYKIPVDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQQIRLQQQQAQQPLQPQPQPQPQPRGAYTRF", "length": 967 }, "evidence": [ { "id": "A0A8V0ZF59", "url": "https://omabrowser.org/oma/group/A0A8V0ZF59/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1RMS6-1", "protein_name": "Integrator complex subunit 7", "gene_name": "INTS7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTAYPSTRMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLATLSGTIAVKHYFSIASGNVGSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSAQDTARILMCHCLAAIAMQLPVLGDGMLGDLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSNGWTVYRIARQASRMGNHDMARELYQTLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKLSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEALILDPESASFQEYGSTGAAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNAIISLLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRRIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYTRF", "length": 962 }, "evidence": [ { "id": "A0A8V0ZF59", "url": "https://omabrowser.org/oma/group/A0A8V0ZF59/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TQK1-1", "protein_name": "Integrator complex subunit 7", "gene_name": "Ints7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDALLASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAVQDLKLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVVPGNVGSSPRSSDLVKLAQECCYHSNRGIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLESLLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSSQDAARILMCHCLAAIAMQLPVLGDGMLGDLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEDSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHADSEYERRMMSVYSRVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRSPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRRVQSVCLNVSSTLQSKSGQDYKIPIDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQQIRLQQQAQQPLQPQPLPQPQPRSAYTRF", "length": 966 }, "evidence": [ { "id": "A0A8V0ZF59", "url": "https://omabrowser.org/oma/group/A0A8V0ZF59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8JGR7-1", "protein_name": "Integrator complex subunit 7", "gene_name": "ints7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLSAARSFLSEAAYGEQELDANSALMELDKGLRSCKLGEQCEAVVLFPKLFQKYPFPILINSAFLKLADIFRLGNNFLRLCVLKVTQLSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAASFSSHSKDFAAGICNKISEMIQGLDTPVELKLKLIPMLQHMHHDASLASCSRELLQELVSSYPSTSMLIVTLHTFTQLATSSLVDIPEQICLLLQYLKEDPRKAVKRLSIQDLKLLAKKAPHLWTRKNIQVLCECALHTPYNSLKLGMLSVLSTLSGTIAIKQYFSPNAGDSSPAPHHTDLVKLAQECCYHSDLAVAAHGITVLTSIAAFCPEKEVIQLEQETVMGMESLILLCSQDDSKTAQATLKTALTSLVQMLKTCPHLSQSSVELLLRQLHCACDPARVLMCQALAAIATQQPVLVEGMLGDLLELFRVASHRTSEKQQELLVSLATVLFVASQASLSAEVKAVIRQQLENVANGWTVYQIARQASRMGCHDFSRELYQSLRTRVASEHFYFWLNSLMEFSQAEQCLSGLEDGDYSAAMSAISEALKSYQKGIASLTAASTPLSPLTFQCEFVKLRIDTLQALSQLICTCNSLKTSPPPAIATTIALSSGSDLQRCGRISTQMKFSMDEFRSLAARYADLYQSSFDADYATLRNVELQQQSCLLVSYVIEALIIDPQTASFQEFGTHGSILAESEYELRMMAVFNHVLEEVENLSRKHPPVSYLHTGCLCDTVIAILKIPLSFQRYFFQKLQSTSIKLALSPSPRTPNEPIPVQNNQQLTLKVEGVIQHGSSPGLFRKIQAVCLKVSSTLQTKPGSDFKIPLESKTNEIEQKVEPHNDYFSTQFLLNFSILGTHQVSVEASVVDTSGIEWKTGPKNTVSVKSLEDPYSQQLRHQLQQQQQNVPQPAAQRNISTRFQ", "length": 964 }, "evidence": [ { "id": "A0A8V0ZF59", "url": "https://omabrowser.org/oma/group/A0A8V0ZF59/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NVH2-1", "protein_name": "Integrator complex subunit 7", "gene_name": "INTS7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGRSATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHDMAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEALILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYTRF", "length": 962 }, "evidence": [ { "id": "A0A8V0ZF59", "url": "https://omabrowser.org/oma/group/A0A8V0ZF59/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VT41-1", "protein_name": "Integrator complex subunit 7", "gene_name": "defl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZF69-1", "uniprot_ac": "A0A8V0ZF69", "uniprot_id": "A0A8V0ZF69_CHICK", "mass": { "chemical_mass": 34891.0, "monoisotopic_mass": 34891.0 }, "refseq": { "ac": "XP_015152657", "name": "transmembrane protein 82 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152657" }, "gene_names": [ { "name": "TMEM82", "type": "recommended", "evidence": [ { "id": "A0A8V0ZF69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF69" } ] }, { "name": "TMEM82", "type": "synonym", "evidence": [ { "id": "XP_015152657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152657" } ] } ], "protein_names": [ { "name": "Transmembrane protein 82", "type": "synonym", "evidence": [ { "id": "A0A8V0ZF69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF69/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 82 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015152657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152657" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152657" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF69", "locus": { "chromosome": "21", "start_pos": 4223887, "end_pos": 4220679, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021800", "url": "https://www.ensembl.org/id/ENSGALG00010021800" } ] } } ], "crossref": [ { "id": "A0A8V0ZF69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZF69", "database": "AlphaFoldDB", "categories": [] }, { "id": "771495", "url": "https://www.ncbi.nlm.nih.gov/gene/771495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771495", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771495", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZF69", "url": "https://www.orthodb.org/?gene=A0A8V0ZF69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35257:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35257:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15816", "url": 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"A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDEILRGEPKMAEVTARATPGAGRRVSVSEFLCHCCYDILVNPTTLNCGHSFCRHCLALWWVSSKKNECPECREKWEGFPRVNILLRDVIERLFSDAIEQRKEDIQQNSDVVRSLATFRKYGNDQISTAPNMGRINPRGRGFFSGVLTALTLLLGYHWSSREFEDDLLVHKPVAKWTAEEVALWLEQLGPWASLYKERFLMEKVNGRLLLTLTEEDFTKEPYSIENNNHKKAITAELECVKTLGVKPPQNLWEYKAVNPGKSLFLLYALKNSPRLSMLYLYLFDYTEAFLPFIHTICPMQEDQYEDMVTKLLDLKDPTWKQWREFTVKYIFLPYQLVAEFAWDWLDVHYWTSRFIIVNAMLLSVLELFSFWKLWSRRELKTIPHRMWKHFWKVSTQGLFVAVFWPFIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVQ", "length": 445, "header": "tr|A0A8V0ZF84-1|A0A8V0ZF84_CHICK Isoform 1 of Bifunctional apoptosis regulator OS=Gallus gallus OX=9031 GN=BFAR PE=4 SV=1 CANONICAL=A0A8V0ZF84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84/entry#A0A8V0ZF84-1", "sequence": { "sequence": "MEEDEILRGEPKMAEVTARATPGAGRRVSVSEFLCHCCYDILVNPTTLNCGHSFCRHCLALWWVSSKKNECPECREKWEGFPRVNILLRDVIERLFSDAIEQRKEDIQQNSDVVRSLATFRKYGNDQISTAPNMGRINPRGRGFFSGVLTALTLLLGYHWSSREFEDDLLVHKPVAKWTAEEVALWLEQLGPWASLYKERFLMEKVNGRLLLTLTEEDFTKEPYSIENNNHKKAITAELECVKTLGVKPPQNLWEYKAVNPGKSLFLLYALKNSPRLSMLYLYLFDYTEAFLPFIHTICPMQEDQYEDMVTKLLDLKDPTWKQWREFTVKYIFLPYQLVAEFAWDWLDVHYWTSRFIIVNAMLLSVLELFSFWKLWSRRELKTIPHRMWKHFWKVSTQGLFVAVFWPFIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVQ", "length": 445, "header": "tr|A0A8V0ZF84-1|A0A8V0ZF84_CHICK Isoform 1 of Bifunctional apoptosis regulator OS=Gallus gallus OX=9031 GN=BFAR PE=4 SV=1 CANONICAL=A0A8V0ZF84-1" }, "locus": { "chromosome": "14", "start_pos": 847734, "end_pos": 843044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049902.1", "url": "https://www.ensembl.org/id/ENSGALT00010049902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029471.1", "url": "https://www.ensembl.org/id/ENSGALP00010029471.1" } ] } }, { "isoform_ac": "A0A8V0ZFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84/entry#A0A8V0ZFG2-1", "sequence": { "sequence": "MEEDEILRGEPKMAEVTARATPGAGRRVSVSEFLCHCCYDILVNPTTLNCGHSFCRHCLALWWVSSKKNECPECREKWEGFPRVNILLRDVIERLFSDAIEQRKEDIQQNSDVVRSLATFRKYGNDQISTAPNMGRINPRGRGFFSGVLTALTCVAVVLLGYHWSSREFEDDLLVHKPVAKWTAEEVALWLEQLGPWASLYKERFLMEKVNGRLLLTLTEEDFTKEPYSIENNNHKKAITAELECVKTLGVKPPQNLWEYKAVNPGKSLFLLYALKNSPRLSMLYLYLFDYTEAFLPFIHTICPMQEDQYEDMVTKLLDLKDPTWKQWREFTVKYIFLPYQLVAEFAWDWLDVHYWTSRFIIVNAMLLSVLELFSFWKLWSRRELKTIPHRMWKHFWKVSTQGLFVAVFWPFIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVQ", "length": 449, "header": "tr|A0A8V0ZFG2-1|A0A8V0ZFG2_CHICK Computationally mapped isoform of Bifunctional apoptosis regulator OS=Gallus gallus OX=9031 GN=BFAR PE=4 SV=1 CANONICAL=A0A8V0ZF84-1" }, "locus": { "chromosome": "14", "start_pos": 847734, "end_pos": 843044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049910.1", "url": "https://www.ensembl.org/id/ENSGALT00010049910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029475.1", "url": "https://www.ensembl.org/id/ENSGALP00010029475.1" } ] } }, { "isoform_ac": "A0A8V0ZLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84/entry#A0A8V0ZLI3-1", "sequence": { "sequence": "MEEDEILRGEPKMAEVTARATPGAGRRVSVSEFLCHCCYDILVNPTTLNCGHSFCRHCLALWWVSSKKNECPECREKWEGFPRVNILLRDVIERLFSDAIEQRKEDIQQNSDVVRSLATFRKYGNDQISTAPNMGRINPRGRGFFSGVLTALTCVAVVLLGYHWSSREFEDDLLVHKPVAKWTAEEVALWLEQLGPWASLYKERFLMEKVNGRLLLTLTEEDFTKEPYSIENNNHKKAITAELECVKTLGVKPPQNLWEYKAVNPGKSLFLLYALKNSPRLSMLYLYLFDYTEAFLPFIHTICPMQEDQYEDMVTKLLSFYPNVQDLKDPTWKQWREFTVKYIFLPYQLVAEFAWDWLDVHYWTSRFIIVNAMLLSVLELFSFWKLWSRRELKTIPHRMWKHFWKVSTQGLFVAVFWPFIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVQ", "length": 456, "header": "tr|A0A8V0ZLI3-1|A0A8V0ZLI3_CHICK Computationally mapped isoform of Bifunctional apoptosis regulator OS=Gallus gallus OX=9031 GN=BFAR PE=4 SV=1 CANONICAL=A0A8V0ZF84-1" }, "locus": { "chromosome": "14", "start_pos": 847734, "end_pos": 843044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049907.1", "url": "https://www.ensembl.org/id/ENSGALT00010049907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029473.1", "url": "https://www.ensembl.org/id/ENSGALP00010029473.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416424", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416424", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GWN6-1", "protein_name": "Bifunctional apoptosis regulator", "gene_name": "Bfar", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEPQKNDPNVAGQEEDSPVISTSPQISVNEFSCHCCYDTLVNPTTLNCGHSFCRHCLALWWMSSKKTECPECREKWEGFPKVNILLRDAIEKLFPDAIRMRIEDIQQNNDIVQSLAAFQKYGNDQSPLTASTGRVNQQRGGGFFSGVLTALTGVAVILLVYHWRSRESEHGLLVHKAVAKWTAEEVVLWLEQLGPWASLYRERFLSERVNGRLLLTLTEEEFSRAPYTIENSSHRRVILMELERVRALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLGLLYLYLFDYTDSFLPFIHTICPLQEGSSGEDILTKLLDLREPTWRQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSRFLIVNAMLLSVLELFSFWKIWSRSELKTVPQRMWSHFWKVSTQGLFMAIFWPLIPQFVCNCLFYWALYFNPIINIDLVVKEVRRLETQVF", "length": 450 }, "evidence": [ { "id": "A0A8V0ZF84", "url": "https://omabrowser.org/oma/group/A0A8V0ZF84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5PQN2-1", "protein_name": "Bifunctional apoptosis regulator", "gene_name": "Bfar", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEPQKNDLSMRGQEEDHPVRSSGPQISVSEFSCHCCYDTLVNPTTLNCGHSFCRHCLALWWMSSKKTECPECREKWEGFPKVNILLRDAIEKLFPDAIKMRVEDIQQNNDVVQSLAAFQKYGNDQNPLAPSTGRVNQQRGGGFFSGVLTALTGVAVILLVYHWRSRESEHGLLVHKAVDKWTTEEVVLWLEQLGPWASLYRDRFLSERVNGRLLLTLTEEEFSRAPYTIENSSHRRVILMELERVRALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLGLLYLYLFDYTDSFLPFIHTICPLQEDSFGEDIFTKLLDLREPTWKQWREFLIKYSFLPYQLIAEFAWDWLEVHYWTSRFLIVNAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFMAMFWPLIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVF", "length": 450 }, "evidence": [ { "id": "A0A8V0ZF84", "url": "https://omabrowser.org/oma/group/A0A8V0ZF84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R079-1", "protein_name": "Bifunctional apoptosis regulator", "gene_name": "Bfar", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEPQKNDLSMREQEEEHPVRSSGPQISVSEFSCHCCYDTLVNPTTLNCGHSFCRHCLALWWMSSKKTECPECREKWEGFPKVNILLRDAIEKLFPDAIRMRVEDIQQNNDVVQSLAAFQKYGNDQNPLAPSTGRVNPQRGGGFFSGVLTALTGVAVILLVYHWRSRESEHGLLVHKAVDKWTMEEVVLWLEQLGPWASLYRDRFLSERVNGRLLLTLTEEEFSRAPYTIENSSHRRVILTELERVRALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLGLLYLYLFDYTDCFLPFIHTICPLQENSSGEDIFTKLLDLREPTWKQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSRFLIVNAVLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFMAMFWPLIPQFVCNCLFYWALYFNPIINIDLVVKEVRRLETQVL", "length": 450 }, "evidence": [ { "id": "A0A8V0ZF84", "url": "https://omabrowser.org/oma/group/A0A8V0ZF84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZS9-1", "protein_name": "Bifunctional apoptosis regulator", "gene_name": "BFAR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEPQKSYVNTMDLERDEPLKSTGPQISVSEFSCHCCYDILVNPTTLNCGHSFCRHCLALWWASSKKTECPECREKWEGFPKVSILLRDAIEKLFPDAIRLRFEDIQQNNDIVQSLAAFQKYGNDQIPLAPNTGRANQQMGGGFFSGVLTALTGVAVVLLVYHWSSRESEHDLLVHKAVAKWTAEEVVLWLEQLGPWASLYRERFLSERVNGRLLLTLTEEEFSKTPYTIENSSHRRAILMELERVKALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLSLLYLYLFDYTDTFLPFIHTICPLQEDSSGEDIVTKLLDLKEPTWKQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSRFLIINAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFVAMFWPLIPQFVCNCLFYWALYFNPIINIDLVVKELRRLETQVL", "length": 450 }, "evidence": [ { "id": "A0A8V0ZF84", "url": "https://omabrowser.org/oma/group/A0A8V0ZF84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "caspase binding", "id": "GO:0089720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089720", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" }, { "name": "negative regulation of IRE1-mediated unfolded protein response", "id": "GO:1903895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 75, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF84" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 245, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 21 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHE1-1", "uniprot_ac": "A0A8V0ZHE1", "uniprot_id": "A0A8V0ZHE1_CHICK", "mass": { "chemical_mass": 51973.0, "monoisotopic_mass": 51973.0 }, "refseq": {}, "gene_names": [ { "name": "ANXA7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.", "evidence": [ { "database": "UniProtKB", "id": "E1C1D1", "url": "https://www.uniprot.org/uniprotkb/E1C1D1#function" }, { "database": "UniProtKB", "id": "ARBA00037210", "url": "https://www.uniprot.org/uniprotkb/ARBA00037210#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANXA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1", "locus": { "chromosome": "6", "start_pos": 16964249, "end_pos": 16979714, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021248", "url": "https://www.ensembl.org/id/ENSGALG00010021248" } ] } } ], "crossref": [ { "id": "A0A8V0ZHE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005299", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005299", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423747", "url": "https://www.ncbi.nlm.nih.gov/gene/423747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423747", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423747", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRGPLMQ", "url": "https://omabrowser.org/oma/group/VRGPLMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZHE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1D1", "url": "https://www.orthodb.org/?gene=E1C1D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1D1", "url": "https://www.uniprot.org/uniprotkb/E1C1D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1D1-1", "url": "https://www.uniprot.org/uniprotkb/E1C1D1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRLTACQLPGLHLKLHVLLENRMAYPGYPPSGYPAFPGYPPTGQESVYPPAGQYTYPAAPGGYPPAGGGSFPAAPPSTGYPEAGGYPAPGGYPAPGGFPGAPQAGGMPSYPGGPGYGVPPTGPGFGGYPQPPAQSYAGGGPAQIPVGYPGGQAPSPMPGPPAAMVQYTQGTIQAAPNFDAGRDAEILRKAMKGIGTDEKAIIDVVSNRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNVEELILALFMPRTYYDAWSLRHAMKGAGTQERVLIEILCTRTNQEIREIVNCYKSEFGRDIEQDIRADTSGHFERLLVSMCQGNRDENQTVDYQKAQEDAQRLYQAGEGKLGTDESCFNMVLASRSFPQLRATAEAYSRIANRDLASSIDREFSGNVERGLKAILQCAFDRPAFFAERLYYAMKGAGTDDSTLIRIIVTRSEIDLVQIKQKFAEMYQKTLATMIASDTSGDYRRLLLAIVGQ", "length": 482, "header": "tr|A0A8V0ZHE1-1|A0A8V0ZHE1_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA7 PE=1 SV=1 CANONICAL=A0A8V0ZHE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1/entry#A0A8V0ZHE1-1", "sequence": { "sequence": "MTRLTACQLPGLHLKLHVLLENRMAYPGYPPSGYPAFPGYPPTGQESVYPPAGQYTYPAAPGGYPPAGGGSFPAAPPSTGYPEAGGYPAPGGYPAPGGFPGAPQAGGMPSYPGGPGYGVPPTGPGFGGYPQPPAQSYAGGGPAQIPVGYPGGQAPSPMPGPPAAMVQYTQGTIQAAPNFDAGRDAEILRKAMKGIGTDEKAIIDVVSNRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNVEELILALFMPRTYYDAWSLRHAMKGAGTQERVLIEILCTRTNQEIREIVNCYKSEFGRDIEQDIRADTSGHFERLLVSMCQGNRDENQTVDYQKAQEDAQRLYQAGEGKLGTDESCFNMVLASRSFPQLRATAEAYSRIANRDLASSIDREFSGNVERGLKAILQCAFDRPAFFAERLYYAMKGAGTDDSTLIRIIVTRSEIDLVQIKQKFAEMYQKTLATMIASDTSGDYRRLLLAIVGQ", "length": 482, "header": "tr|A0A8V0ZHE1-1|A0A8V0ZHE1_CHICK Isoform 1 of Annexin OS=Gallus gallus OX=9031 GN=ANXA7 PE=1 SV=1 CANONICAL=A0A8V0ZHE1-1" }, "locus": { "chromosome": "6", "start_pos": 16979515, "end_pos": 16964468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051523.1", "url": "https://www.ensembl.org/id/ENSGALT00010051523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030714.1", "url": "https://www.ensembl.org/id/ENSGALP00010030714.1" } ] } }, { "isoform_ac": "E1C1D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1/entry#E1C1D1-1", "sequence": { "sequence": "MAYPGYPPSGYPAFPGYPPTGQESVYPPAGQYTYPAAPGGYPPAGGGSFPAAPPSTGYPEAGGYPAPGGYPAPGGFPGAPQAGGMPSYPGGPGYGVPPTGPGFGGYPQPPAQSYAGGGPAQIPVGYPGGQAPSPMPGPPAAMVQYTQGTIQAAPNFDAGRDAEILRKAMKGIGTDEKAIIDVVSNRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNVEELILALFMPRTYYDAWSLRHAMKGAGTQERVLIEILCTRTNQEIREIVNCYKSEFGRDIEQDIRADTSGHFERLLVSMCQGNRDENQTVDYQKAQEDAQRLYQAGEGKLGTDESCFNMVLASRSFPQLRATAEAYSRIANRDLASSIDREFSGNVERGLKAILQCAFDRPAFFAERLYYAMKGAGTDDSTLIRIIVTRSEIDLVQIKQKFAEMYQKTLATMIASDTSGDYRRLLLAIVGQ", "length": 459, "header": "tr|E1C1D1-1|A0A8V0ZHE1_CHICK Computationally mapped isoform of Annexin OS=Gallus gallus OX=9031 GN=ANXA7 PE=1 SV=2 CANONICAL=A0A8V0ZHE1-1" }, "locus": { "chromosome": "6", "start_pos": 16975463, "end_pos": 16964468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051517.1", "url": "https://www.ensembl.org/id/ENSGALT00010051517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030708.1", "url": "https://www.ensembl.org/id/ENSGALP00010030708.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423747", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M2V3-1", "protein_name": "Annexin", "gene_name": "Anxa7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYPGYPPTGYPPFPGYPPAGQESSFPPPGQYPYPSGFPPMGGGAYPPAPSVGYPGAGGYATPGGYPAPGGYPVSPSPGGVPVYPGGQGFGAPPGGAGFSGYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGHAPYPSQPAAMTQGTQGTIRAASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSSRSNDQRQQIKTAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQSEFGRDLEKDIKSDTSGHFERLLVSMCQGNRDENQSVNHQMAQDDAQRLYQAGEGKLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYIESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ", "length": 463 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P20072-1", "protein_name": "Annexin A7", "gene_name": "ANXA7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSYPGYPPTGYPPFPGYPPTGQESSFPPPGQYPYPSGFPPMGGGAYPPAPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGGQGFGAPPGGAGFPGYPQPPTQSYGGGPAQVPLPGGFPGGAMPSQYPGGQSPYPSQPAPMTQGTHGTIRPAANFDAMRDAEVLRKAMKGFGTDEQAIIDVVANRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRNAMKGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQNVNHQLAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLNSVSREFSGNVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFSQMYQKTLGTMIASDTSGDYRKLLLAIVGQ", "length": 463 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P20073-1", "protein_name": "Annexin A7", "gene_name": "ANXA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVGQ", "length": 488 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P24639-1", "protein_name": "Annexin A7", "gene_name": "nxnA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSYPPNQGYPPQSNSPQPGQYGAPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQQGYPPQGYPPQQGYPPVGVPVGVPVGFAPGMVVGYHQGYFVGTITHDCKHDAEVLRKAMKGIGTNESDLIKVLANRNWAEREQIKREFSAKYSKDLIQDIKSETSGNFEKCLVALLTEPAHFDVEQIHSACAGAGTNENTIIEILVTRSNVQMEYIKQIFKNKHGKSLKDRLESEASGDFKKLLEKLTEPRDESPVINPMQVSKDAEDLYKAGEGKIGTDEKEFIKILTSRSLPHIAAVASEYIKHHKKHSLIKAIDSEFSGSIKTGLIAIVTYALNPYGYFAEILNKSMKGAGTNDNKLIRTVVTQMHNMPQIKTAYSTLFKNSLAHDIQADCSGDFKKLLLDIIS", "length": 462 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q07076-1", "protein_name": "Annexin A7", "gene_name": "Anxa7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYPGYPPTGYPPFPGYPPAGQESSFPTAGQYPYPSGFPPMGGGAYPPAPSGGYPGAGGYPAPGGYPAPGGYPGALSPGGPPAYPGGQGFGAPPGGAGFSGYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQAPYPSQPASMTQGTQGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ", "length": 463 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SE45-1", "protein_name": "Annexin D3", "gene_name": "ANN3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATIRVPNEVPSPAQDSETLKQAIRGWGTDEKAIIRVLGQRDQSQRRKIRESFREIYGKDLIDVLSSELSGDFMKAVVSWTYDPAERDARLVNKILNKEKKKKSLENLKVIVEISCTTSPNHLIAVRKAYCSLFDSSLEEHIASSLPFPLAKLLVTLASTFRYDKDRTDAEVATIEAAMLREAIEKKQLDHDHVLYILGTRSIYQLRETFVAYKKNYGVTIDKDVDGCPGDADLRSLLKVAIFCIDTPEKHFAKVVRDSIEGFGTDEDSLTRAIVTRAEIDLMKVRGEYFNMYNTSMDNAITGDISGDYKDFIITLLGSKI", "length": 321 }, "evidence": [ { "id": "A0A8V0ZHE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHE1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "pmid": "" }, { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE1" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFY3-1", "uniprot_ac": "A0A8V0ZFY3", "uniprot_id": "A0A8V0ZFY3_CHICK", "mass": { "chemical_mass": 52860.0, "monoisotopic_mass": 52860.0 }, "refseq": { "ac": "NP_001025813", "name": "cerebellar degeneration-related protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813" }, "gene_names": [ { "name": "CDR2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3" } ] }, { "name": "CDR2", "type": "synonym", "evidence": [ { "id": "NP_001025813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813" } ] } ], "protein_names": [ { "name": "Cerebellar deration related protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3/entry#names_and_taxonomy" } ] }, { "name": "cerebellar degeneration-related protein 2, 62kDa", "type": "synonym", "evidence": [ { "id": "NP_001025813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813" } ] }, { "name": "cerebellar degeneration-related protein 2", "type": "synonym", "evidence": [ { "id": "NP_001025813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720531.1, SRR13267662.42481.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001025813.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025813", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3", "locus": { "chromosome": "14", "start_pos": 8709975, "end_pos": 8724735, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019030", "url": "https://www.ensembl.org/id/ENSGALG00010019030" } ] } } ], "crossref": [ { "id": "A0A8V0ZFY3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "416621", "url": "https://www.ncbi.nlm.nih.gov/gene/416621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416621", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCRARQK", "url": "https://omabrowser.org/oma/group/GCRARQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2M5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8H5", "url": "https://www.orthodb.org/?gene=A0A8V0Z8H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFY3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19232:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19232:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025813", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025813", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLADSLVEEFEIREDEPWYDQQDLQQDLHLAAELGKTLLDRNTELEESLQQMYATNQEQLQEIEYLTKQVELLRQMNDQHAKVYEQLDVTARELEDTNQKLVAESRASQQKILSLTETIENLQTHVDDLQRQVEELKKSGRGRMNHERSDQPRSMHSFSCLKELYDLRQYFVYDHVFAEKITSMDSQLNPLEEENENLKKAVTVLQAQLNLEKEKRVTMEEEYSLVVKENCDLEQRLVDIDLYRARAEELEVEVAEMRQMLQSENTIHSAEKLVPESFFISFKESLERELGQSPADDGLLTVPELDKKALKRSSSENFLSSAAGGDILRGHEETCIRRAEAVKQRGISVLNEVDAQYNALKVKYEELLKKCQIDEDSLKHKAVQTLKQYSKDSVGNTQYDLSANNQEFTNAGELLSSTNTLPEYKALFKEIFSCIKKTKEEIDEHRSKYKSLSSQP", "length": 456, "header": "tr|A0A8V0ZFY3-1|A0A8V0ZFY3_CHICK Isoform 1 of Cerebellar deration related protein 2 OS=Gallus gallus OX=9031 GN=CDR2 PE=3 SV=1 CANONICAL=A0A8V0ZFY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3/entry#A0A8V0Z2M5-1", "sequence": { "sequence": "MELLDGTNLHLAAELGKTLLDRNTELEESLQQMYATNQEQLQEIEYLTKQVELLRQMNDQHAKVYEQLDVTARELEDTNQKLVAESRASQQKILSLTETIENLQTHVDDLQRQVEELKKSGRGRMNHERSDQPRSMHSFSCLKELYDLRQYFVYDHVFAEKITSMDSQLNPLEEENENLKKAVTVLQAQLNLEKEKRVTMEEEYSLVVKENCDLEQRLVDIDLYRARAEELEVEVAEMRQMLQSENTIHSAEKLVPESFFISFKESLERELGQSPADDGLLTVPELDKKALKRSSSENFLSSAAGGDILRGHEETCIRRAEAVKQRGISVLNEVDAQYNALKVKYEELLKKCQIDEDSLKHKAVQTLKQYSKDSVGNTQYDLSANNQEFTNAGELLSSTNTLPEYKALFKEIFSCIKKTKEEIDEHRSKYKSLSSQP", "length": 437, "header": "tr|A0A8V0Z2M5-1|A0A8V0ZFY3_CHICK Computationally mapped isoform of Cerebellar deration related protein 2 OS=Gallus gallus OX=9031 GN=CDR2 PE=3 SV=1 CANONICAL=A0A8V0ZFY3-1" }, "locus": { "chromosome": "14", "start_pos": 8722699, "end_pos": 8713412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046073.1", "url": "https://www.ensembl.org/id/ENSGALT00010046073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027467.1", "url": "https://www.ensembl.org/id/ENSGALP00010027467.1" } ] } }, { "isoform_ac": "A0A8V0Z8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3/entry#A0A8V0Z8H5-1", "sequence": { "sequence": "MRTNKAVLCAGETWSGPGDGKEVKNLHLAAELGKTLLDRNTELEESLQQMYATNQEQLQEIEYLTKQVELLRQMNDQHAKVYEQLDVTARELEDTNQKLVAESRASQQKILSLTETIENLQTHVDDLQRQVEELKKSGRGRMNHERSDQPRSMHSFSCLKELYDLRQYFVYDHVFAEKITSMDSQLNPLEEENENLKKAVTVLQAQLNLEKEKRVTMEEEYSLVVKENCDLEQRLVDIDLYRARAEELEVEVAEMRQMLQSENTIHSAEKLVPESFFISFKESLERELGQSPADDGLLTVPELDKKALKRSSSENFLSSAAGGDILRGHEETCIRRAEAVKQRGISVLNEVDAQYNALKVKYEELLKKCQIDEDSLKHKAVQTLKQYSKDSVGNTQYDLSANNQEFTNAGELLSSTNTLPEYKALFKEIFSCIKKTKEEIDEHRSKYKSLSSQP", "length": 454, "header": "tr|A0A8V0Z8H5-1|A0A8V0ZFY3_CHICK Computationally mapped isoform of Cerebellar deration related protein 2 OS=Gallus gallus OX=9031 GN=CDR2 PE=3 SV=1 CANONICAL=A0A8V0ZFY3-1" }, "locus": { "chromosome": "14", "start_pos": 8721051, "end_pos": 8713412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046070.1", "url": "https://www.ensembl.org/id/ENSGALT00010046070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027464.1", "url": "https://www.ensembl.org/id/ENSGALP00010027464.1" } ] } }, { "isoform_ac": "A0A8V0ZFY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3/entry#A0A8V0ZFY3-1", "sequence": { "sequence": "MLADSLVEEFEIREDEPWYDQQDLQQDLHLAAELGKTLLDRNTELEESLQQMYATNQEQLQEIEYLTKQVELLRQMNDQHAKVYEQLDVTARELEDTNQKLVAESRASQQKILSLTETIENLQTHVDDLQRQVEELKKSGRGRMNHERSDQPRSMHSFSCLKELYDLRQYFVYDHVFAEKITSMDSQLNPLEEENENLKKAVTVLQAQLNLEKEKRVTMEEEYSLVVKENCDLEQRLVDIDLYRARAEELEVEVAEMRQMLQSENTIHSAEKLVPESFFISFKESLERELGQSPADDGLLTVPELDKKALKRSSSENFLSSAAGGDILRGHEETCIRRAEAVKQRGISVLNEVDAQYNALKVKYEELLKKCQIDEDSLKHKAVQTLKQYSKDSVGNTQYDLSANNQEFTNAGELLSSTNTLPEYKALFKEIFSCIKKTKEEIDEHRSKYKSLSSQP", "length": 456, "header": "tr|A0A8V0ZFY3-1|A0A8V0ZFY3_CHICK Isoform 1 of Cerebellar deration related protein 2 OS=Gallus gallus OX=9031 GN=CDR2 PE=3 SV=1 CANONICAL=A0A8V0ZFY3-1" }, "locus": { "chromosome": "14", "start_pos": 8724587, "end_pos": 8713412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046078.1", "url": "https://www.ensembl.org/id/ENSGALT00010046078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027468.1", "url": "https://www.ensembl.org/id/ENSGALP00010027468.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416621", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AT17-1", "protein_name": "Cerebellar deration related protein 2", "gene_name": "CDR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNHKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQRRRSQEKHDQEKSAPSFSCLKELYDLRQHFVYDHVFAEQITSLQSRQSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEFGLVLKENRDLERQLGATDTYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLFAPFREPSQSLLEEMLLTPPEAPRKPLKRSSSETVLSSLAGGDIVKGHEETCIRRAKAVKQRGVSLLHEVDTQYSALKVKYEELLKKCQQDEDSLSHKAVQTSRAPAKELAAVGAQPEPGTSGWEPASVTPEPMASPTASTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS", "length": 456 }, "evidence": [ { "id": "A0A8V0ZFY3", "url": "https://omabrowser.org/oma/group/A0A8V0ZFY3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GL37-1", "protein_name": "Cerebellar degeneration-related protein 2", "gene_name": "Cdr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHATVKANQSQEGNEDSNGLKIGQDFHVVRDEATEKDAGGAHQGCHLVNSGQLQPALVPGGSLCKQATLGLLYPGVGAVKCTQGNYQLESDLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQVEELKSNQGRGRQKACDQERPAPSFSCLKELYDLRQHFVYDHVFAEKITSLQSQQSPDEEENEHLKKAVTMLQAQLSLERKKRVSVEAEYKVVLKENSELEQQLSATDAYRARAQELEAEVAEMRQMLQAEHPFVNGVEKLVPDSLFVPFKEPSQSLLEEMFLAAPEAHRKPLKRSSSETVLSSLAGDDIVKDHEDTCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLRKCQQEQDSLSHKAVQTSRLLTRDLTGLVPQSEAGASGWEPTPVSPEPISSPTTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYPSLSPYS", "length": 519 }, "evidence": [ { "id": "A0A8V0ZFY3", "url": "https://omabrowser.org/oma/group/A0A8V0ZFY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FC97-1", "protein_name": "Cerebellar degeneration-related protein 2", "gene_name": "cdr2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTDVIVEEDFDRSEEELWYSRKDLEHDLHLAAELGKTLLDRNHELEQGLQQMYSTNHEQLQEIEYLTKQVDLLRQMNDQHAKVYEQLDLAARDLEKSNQRLVLENRTSQHRIQSLTETIDGLQAHMESLQKQVDELKASQSRRDFTAARRALGAQSMSCLKEIYDLQQDKSWTSEGLHEERSWPVLSERCVEEEEETSTLQHSLHKLKQQLATERARRVEAERETELTVLENSALEDRLSLLEGARRRQAELEAEVEELRLLWRSESSSSRLTDTLLPDSVFFSAEERLGVEPECEEEAEFPQGRCRCSSDSYVRGARAEEIRRGHERSCIRRAQAVKQRGISLLNEVDAQYSALQLKYEELLRRCQHGANSLSHKAVQTPKSQSCSATDTACLSDQLHQPEYKALFKEIFTCIQKTKEDLSENRALQAQ", "length": 431 }, "evidence": [ { "id": "A0A8V0ZFY3", "url": "https://omabrowser.org/oma/group/A0A8V0ZFY3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P97817-1", "protein_name": "Cerebellar degeneration-related protein 2", "gene_name": "Cdr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLADNLVEEFEMEDEPWYDHRDLQQDLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQVEELKSSSQGRGRQKACDQEKPAPSFSCLKELYDLRQHFVYDHVFAEKITSLQSQQSPDEEENEHLKKAVTMLQAQLSLERKKRVSVEAEYKVVLKENSELEQQLGATDAYRARALELEAEVAEMRQMLQAEHPFVNGVEKLVPDSLFVPFKEPSQSLLEEMFLAAPEAPRKPLKRSSSETALSSLAGDDIVKDHEDTCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQQEQDSLSHKAVQTSRLLTRDLTGLVTQSEAGASGWEPTPVSPESISSPTTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYPSLSSYSY", "length": 455 }, "evidence": [ { "id": "A0A8V0ZFY3", "url": "https://omabrowser.org/oma/group/A0A8V0ZFY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01850-1", "protein_name": "Cerebellar degeneration-related protein 2", "gene_name": "CDR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS", "length": 454 }, "evidence": [ { "id": "A0A8V0ZFY3", "url": "https://omabrowser.org/oma/group/A0A8V0ZFY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGK7-1", "uniprot_ac": "A0A8V0ZGK7", "uniprot_id": "A0A8V0ZGK7_CHICK", "mass": { "chemical_mass": 46617.0, "monoisotopic_mass": 46617.0 }, "refseq": {}, "gene_names": [ { "name": "PIP4K2B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ] } ], "protein_names": [ { "name": "1-phosphatidylinositol-5-phosphate 4-kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.149", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIP4K2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7", "locus": { "chromosome": "27", "start_pos": 4003838, "end_pos": 4020847, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022151", "url": "https://www.ensembl.org/id/ENSGALG00010022151" } ] } } ], "crossref": [ { "id": "A0A8V0ZGK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001610", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17310", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17310", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419999", "url": "https://www.ncbi.nlm.nih.gov/gene/419999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419999", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKSHENA", "url": "https://omabrowser.org/oma/group/MKSHENA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PV96", "url": "https://www.orthodb.org/?gene=A0A1D5PV96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8847453", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8847453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12280", "url": "https://www.rhea-db.org/rhea/12280", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55964", "url": "https://www.rhea-db.org/rhea/55964", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55992", "url": "https://www.rhea-db.org/rhea/55992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PV96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PV96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TEAAGTAAGRGAASKTKTKKKHFVCQKVKLFRASEPLLSVLMWGANHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPLVFRNLRERFGIDDQDYQNSVTRSAPVNSDSQGRCGARFLTTYDRRFVIKAVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVSREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEDRAEDEECENDGLGGNPISSYGTPPDSPGNLLNYPRFFGPGEFDPSVDVYAMKSHDSAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 411, "header": "tr|A0A8V0ZGK7-1|A0A8V0ZGK7_CHICK Isoform 1 of 1-phosphatidylinositol-5-phosphate 4-kinase OS=Gallus gallus OX=9031 GN=PIP4K2B PE=1 SV=1 CANONICAL=A0A8V0ZGK7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PV96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7/entry#A0A1D5PV96-1", "sequence": { "sequence": "MASNCAGGSAAGGGGAALGSALSASKTKTKKKHFVCQKVKLFRASEPLLSVLMWGANHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPLVFRNLRERFGIDDQDYQNSVTRSAPVNSDSQGRCGARFLTTYDRRFVIKAVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVSREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEDRAEDEECENDGLGGNPISSYGTPPDSPGNLLNYPRFFGPGEFDPSVDVYAMKSHDSAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 422, "header": "tr|A0A1D5PV96-1|A0A8V0ZGK7_CHICK Computationally mapped isoform of 1-phosphatidylinositol-5-phosphate 4-kinase OS=Gallus gallus OX=9031 GN=PIP4K2B PE=1 SV=1 CANONICAL=A0A8V0ZGK7-1" }, "locus": { "chromosome": "27", "start_pos": 4020648, "end_pos": 4007816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053898.1", "url": "https://www.ensembl.org/id/ENSGALT00010053898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032454.1", "url": "https://www.ensembl.org/id/ENSGALP00010032454.1" } ] } }, { "isoform_ac": "A0A8V0ZGK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7/entry#A0A8V0ZGK7-1", "sequence": { "sequence": "TEAAGTAAGRGAASKTKTKKKHFVCQKVKLFRASEPLLSVLMWGANHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPLVFRNLRERFGIDDQDYQNSVTRSAPVNSDSQGRCGARFLTTYDRRFVIKAVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVSREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEDRAEDEECENDGLGGNPISSYGTPPDSPGNLLNYPRFFGPGEFDPSVDVYAMKSHDSAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 411, "header": "tr|A0A8V0ZGK7-1|A0A8V0ZGK7_CHICK Isoform 1 of 1-phosphatidylinositol-5-phosphate 4-kinase OS=Gallus gallus OX=9031 GN=PIP4K2B PE=1 SV=1 CANONICAL=A0A8V0ZGK7-1" }, "locus": { "chromosome": "27", "start_pos": 4020772, "end_pos": 4007816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053890.1", "url": "https://www.ensembl.org/id/ENSGALT00010053890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032448.1", "url": "https://www.ensembl.org/id/ENSGALP00010032448.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419999", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-6811555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811555", "resource": "Reactome", "description": "PI5P Regulates TP53 Acetylation" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-8847453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8847453", "resource": "Reactome", "description": "Synthesis of PIPs in the nucleus" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480I421-1", "protein_name": "1-phosphatidylinositol-5-phosphate 4-kinase", "gene_name": "PIP4K2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGMGGSLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGK7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MHT2-1", "protein_name": "1-phosphatidylinositol-5-phosphate 4-kinase", "gene_name": "PIP4K2B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGMGGSLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGK7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88377-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "gene_name": "Pip4k2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLRVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEETEVEDRAEEEECENDGVGGGLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P78356-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "gene_name": "PIP4K2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80XI4-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "gene_name": "Pip4k2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEEEECENDGVGGSLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESAPKKEVYFMAIIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "id": "GO:1902635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "1-phosphatidylinositol-5-phosphate 4-kinase activity", "id": "GO:0016309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016309", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12280", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XM27-1", "A0A8V0ZWL6-1", "Q5F356-1", "A0A8V0ZGK7-1" ], "evidence": [ { "id": "12280", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12280" } ] }, { "id": "55964", "name": "", "equation": "1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XM27-1", "A0A8V0ZWL6-1", "Q5F356-1", "A0A8V0ZGK7-1" ], "evidence": [ { "id": "55964", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55964" } ] }, { "id": "55992", "name": "", "equation": "1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XM27-1", "A0A8V0ZWL6-1", "Q5F356-1", "A0A8V0ZGK7-1" ], "evidence": [ { "id": "55992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55992" } ] }, { "id": "R-GGA-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-1806240" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZGK7-1", "A0A8V0ZWL6-1", "A0A8V0XM27-1" ], "evidence": [ { "id": "R-GGA-1675776", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1675776" } ] }, { "id": "R-GGA-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-1806276" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZGK7-1", "A0A8V0XM27-1" ], "evidence": [ { "id": "R-GGA-1676145", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1676145" } ] }, { "id": "R-GGA-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-ALL-6810408" ], "output_participant_list": [ "R-ALL-113582", "R-ALL-6810412" ], "enzyme_list": [ "A0A8V0ZGK7-1", "A0A8V0ZWL6-1", "A0A8V0XM27-1" ], "evidence": [ { "id": "R-GGA-6811522", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811522" } ] }, { "id": "R-GGA-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A8V0ZGK7-1", "A0A8V0ZWL6-1", "A0A8V0XM27-1" ], "evidence": [ { "id": "R-GGA-8877691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8877691" } ] }, { "id": "R-GGA-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZGK7-1", "A0A8V0ZWL6-1", "A0A8V0XM27-1", "A0A8V0XB51-1" ], "evidence": [ { "id": "R-GGA-8877692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8877692" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113582", "participant_name": "ADP [nucleoplasm]", "crossref": [ { "id": "ZINC000012360703", "database": "ZINC", "url": "" }, { "id": "C00008", "database": "COMPOUND", "url": "" }, { "id": "456216", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1806240", "participant_name": "PI5P [plasma membrane]", "crossref": [ { "id": "57795", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1806276", "participant_name": "PI3P [plasma membrane]", "crossref": [ { "id": "58088", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6810408", "participant_name": "PI5P [nucleoplasm]", "crossref": [ { "id": "57795", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6810412", "participant_name": "PI(4,5)P2 [nucleoplasm]", "crossref": [ { "id": "58456", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XB51", "gene_name": "PIN1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] } ] }, { "uniprot_ac": "A0A8V0XM27", "gene_name": "PIP4K2A", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0XM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM27" } ] }, { "ec_number": "2.7.1.149", "activity": "", "evidence": [ { "id": "A0A8V0XM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM27" } ] } ] }, { "uniprot_ac": "A0A8V0ZGK7", "gene_name": "PIP4K2B", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ] }, { "ec_number": "2.7.1.149", "activity": "", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGK7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWL6", "gene_name": "PIP4K2C", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWL6" } ] }, { "ec_number": "2.7.1.149", "activity": "", "evidence": [ { "id": "A0A8V0ZWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWL6" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "Q5F356", "gene_name": "PIP4K2A", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIN8-1", "uniprot_ac": "A0A8V0ZIN8", "uniprot_id": "A0A8V0ZIN8_CHICK", "mass": { "chemical_mass": 58169.0, "monoisotopic_mass": 58169.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Bifunctional coenzyme A synthase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.24", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Bifunctional enzyme that catalyzes the fourth step of the coenzyme A biosynthetic pathway, the adenylation of 4'-phosphopantetheine, and the fifth step, the phosphorylation of dephospho-CoA to CoA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8#function" }, { "database": "UniProtKB", "id": "ARBA00094100", "url": "https://www.uniprot.org/uniprotkb/ARBA00094100#function" } ] }, { "annotation": "Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN7#function" }, { "database": "UniProtKB", "id": "ARBA00053727", "url": "https://www.uniprot.org/uniprotkb/ARBA00053727#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZIN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02164", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02164", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19687", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19687", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10695:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10695:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196783", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196783", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "18245", "url": "https://www.rhea-db.org/rhea/18245", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19801", "url": "https://www.rhea-db.org/rhea/19801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPFPSGLLVLTAPLGALPRRAAAALAEAAGVVTGPLYVHLQPGLRLDGPAPRPAAPPPAAALLRALAALYAAAAAHRGLDVRVLLGHGHRLARPPRVLLADGGAGDAGPVRVALRELAAAAYGCPPGLPALLLSGTDGPEALPDGSGAELPAYPDVAVGGTFDRLHGAHRLLLSACCLLARRRLLVGVADGELLRHKVLRELIEPYELRAAKLREFLLDVQPSVLYDIVPLGDPYGPAITDPELRCIVVSSETRRGGEAVNKKRIENGLAALELFEIELMEDPQHGLNEEEKISSSSLRQRLLGTLLQPPRDSPTLPPHPYIIGLTGGSGSGKTSIAHRLEQMGAFLIDADALGHAAYLPGSPAHGRVVAAFGAEILNKDGTINRKVLGAKVFGDQERLKSLTDIVWPEIARMVRERIAEAGAEGKAVVVLDAAVLLEAGWQEMVHEVWAAIIPEEEAVKRIVRRDGLSEEAARSRLRSQMSDSQRVRQAQVVLCTLWEPEVTRRQVEKAWELLQQRLSRAPAGAAVHLSAAWRPRAAGTGEEPP", "length": 546, "header": "tr|A0A8V0ZIN8-1|A0A8V0ZIN8_CHICK Isoform 1 of Bifunctional coenzyme A synthase OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZIN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#A0A8V0ZBN7-1", "sequence": { "sequence": "MEDPQHGLNEEEKISSSSLRQRLLGTLLQPPRDSPTLPPHPYIIGLTGGSGSGKTSIAHRLEQMGAFLIDADALGHAAYLPGSPAHGRVVAAFGAEILNKDGTINRKVLGAKVFGDQERLKSLTDIVWPEIARMVRERIAEAGAEGKAVVVLDAAVLLEAGWQEMVHEVWAAIIPEEEAVKRIVRRDGLSEEAARSRLRSQMSDSQRVRQAQVVLCTLWEPEVTRRQVDAAYGDSGPEPALFMDGARKGSVVSRANSIGSTSASSVPNTDDEDSDYPQEHYKESYKDQRRRAHTQAEQKRRNAIKKGYDDLQAIVPTCQQQDFSISSQKLSKAIILQKTIDYIQFLHKEKKKQEEEVSTLRKDVMALKIMKVNYEQIVKAHQDNPSEGKDQVSDQVKFNVFQGIMDSLFESFNASISVTSFQELSACVFSWIEEHCKPHTLRDIVMGVLHQVKSQLY", "length": 457, "header": "tr|A0A8V0ZBN7-1|A0A8V0ZIN8_CHICK Computationally mapped isoform of Bifunctional coenzyme A synthase OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZIN8-1" }, "locus": { "chromosome": "27", "start_pos": 4968192, "end_pos": 4963556, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051497.1", "url": "https://www.ensembl.org/id/ENSGALT00010051497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030692.1", "url": "https://www.ensembl.org/id/ENSGALP00010030692.1" } ] } }, { "isoform_ac": "A0A8V0ZIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#A0A8V0ZIN8-1", "sequence": { "sequence": "MAPFPSGLLVLTAPLGALPRRAAAALAEAAGVVTGPLYVHLQPGLRLDGPAPRPAAPPPAAALLRALAALYAAAAAHRGLDVRVLLGHGHRLARPPRVLLADGGAGDAGPVRVALRELAAAAYGCPPGLPALLLSGTDGPEALPDGSGAELPAYPDVAVGGTFDRLHGAHRLLLSACCLLARRRLLVGVADGELLRHKVLRELIEPYELRAAKLREFLLDVQPSVLYDIVPLGDPYGPAITDPELRCIVVSSETRRGGEAVNKKRIENGLAALELFEIELMEDPQHGLNEEEKISSSSLRQRLLGTLLQPPRDSPTLPPHPYIIGLTGGSGSGKTSIAHRLEQMGAFLIDADALGHAAYLPGSPAHGRVVAAFGAEILNKDGTINRKVLGAKVFGDQERLKSLTDIVWPEIARMVRERIAEAGAEGKAVVVLDAAVLLEAGWQEMVHEVWAAIIPEEEAVKRIVRRDGLSEEAARSRLRSQMSDSQRVRQAQVVLCTLWEPEVTRRQVEKAWELLQQRLSRAPAGAAVHLSAAWRPRAAGTGEEPP", "length": 546, "header": "tr|A0A8V0ZIN8-1|A0A8V0ZIN8_CHICK Isoform 1 of Bifunctional coenzyme A synthase OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZIN8-1" }, "locus": { "chromosome": "27", "start_pos": 4965550, "end_pos": 4962248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051468.1", "url": "https://www.ensembl.org/id/ENSGALT00010051468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030660.1", "url": "https://www.ensembl.org/id/ENSGALP00010030660.1" } ] } }, { "isoform_ac": "A0A8V0ZIQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8/entry#A0A8V0ZIQ2-1", "sequence": { "sequence": "MVVFGGLSDVPSRQGLAALELFEIELMEDPQHGLNEEEKISSSSLRQRLLGTLLQPPRDSPTLPPHPYIIGLTGGSGSGKTSIAHRLEQMGAFLIDADALGHAAYLPGSPAHGRVVAAFGAEILNKDGTINRKVLGAKVFGDQERLKSLTDIVWPEIARMVRERIAEAGAEGKAVVVLDAAVLLEAGWQEMVHEVWAAIIPEEEAVKRIVRRDGLSEEAARSRLRSQMSDSQRVRQAQVVLCTLWEPEVTRRQVDAAYGDSGPEPALFMDGARKGSVVSRANSIGSTSASSVPNTDDEDSDYPQEHYKESYKDQRRRAHTQAEQKRRNAIKKGYDDLQAIVPTCQQQDFSISSQKLSKAIILQKTIDYIQFLHKEKKKQEEEVSTLRKDVMALKIMKVNYEQIVKAHQDNPSEGKDQVSDQVKFNVFQGIMDSLFESFNASISVTSFQELSACVFSWIEEHCKPHTLRDIVMGVLHQVKSQLY", "length": 483, "header": "tr|A0A8V0ZIQ2-1|A0A8V0ZIN8_CHICK Computationally mapped isoform of Bifunctional coenzyme A synthase OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZIN8-1" }, "locus": { "chromosome": "27", "start_pos": 4968192, "end_pos": 4963478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051480.1", "url": "https://www.ensembl.org/id/ENSGALT00010051480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030671.1", "url": "https://www.ensembl.org/id/ENSGALP00010030671.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-196783", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196783", "resource": "Reactome", "description": "Coenzyme A biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "dephospho-CoA kinase activity", "id": "GO:0004140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "pantetheine-phosphate adenylyltransferase activity", "id": "GO:0004595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" }, { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18245", "name": "", "equation": "3'-dephospho-CoA + ATP = ADP + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZIN8-1" ], "evidence": [ { "id": "18245", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18245" } ] }, { "id": "19801", "name": "", "equation": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZIN8-1" ], "evidence": [ { "id": "19801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19801" } ] }, { "id": "R-GGA-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [ "R-ALL-196767" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZIN8-1" ], "evidence": [ { "id": "R-GGA-196754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196754" } ] }, { "id": "R-GGA-196773", "name": "COASY phosphorylates DP-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [ "R-ALL-196778" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZIN8-1" ], "evidence": [ { "id": "R-GGA-196773", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196773" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-196767", "participant_name": "PPANT [cytosol]", "crossref": [ { "id": "61723", "database": "ChEBI", "url": "" }, { "id": "PANTETHEINE-P", "database": "AraCyc", "url": "" }, { "id": "C01134", "database": "KEGG Gene", "url": "" }, { "id": "25245905", "database": "PubChem Compound", "url": "" }, { "id": "ZINC000012495122", "database": "ZINC", "url": "" }, { "id": "C01134", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-196778", "participant_name": "DP-CoA [cytosol]", "crossref": [ { "id": "57328", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551261", "database": "ZINC", "url": "" }, { "id": "C00882", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZIN8", "gene_name": "", "activity": [ { "ec_number": "2.7.1.24", "activity": "3'-dephospho-CoA + ATP = ADP + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ] }, { "ec_number": "2.7.7.3", "activity": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate.", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ] }, { "ec_number": "2.7.7.3", "activity": "", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ] }, { "ec_number": "2.7.1.24", "activity": "", "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN8" }, { "id": "PF01467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytidyltransferase-like", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 302, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.24", "ec_name": "3'-dephospho-CoA + ATP = ADP + CoA + H(+).", "evidence": [ { "id": "2.7.1.24", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.24" }, { "id": "2.7.1.24", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.24" } ] }, { "ec_number": "2.7.7.3", "ec_name": "(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate.", "evidence": [ { "id": "2.7.7.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.3" }, { "id": "2.7.7.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 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"MKQSPDVQGCCCSSHPSDGGAGGPSVCRTGGQLCMQLVEHRRGWPLPFAFMFIVSTELNVETHGGWVRYLGGAPSDPNCISIILHMCLFLGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1540, "header": "tr|A0A8V0ZFM2-1|A0A8V0ZFM2_CHICK Isoform 1 of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZFM2-1", "sequence": { "sequence": "MKQSPDVQGCCCSSHPSDGGAGGPSVCRTGGQLCMQLVEHRRGWPLPFAFMFIVSTELNVETHGGWVRYLGGAPSDPNCISIILHMCLFLGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1540, "header": "tr|A0A8V0ZFM2-1|A0A8V0ZFM2_CHICK Isoform 1 of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1091393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053259.1", "url": "https://www.ensembl.org/id/ENSGALT00010053259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032098.1", "url": "https://www.ensembl.org/id/ENSGALP00010032098.1" } ] } }, { "isoform_ac": "A0A8V0ZFM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZFM7-1", "sequence": { "sequence": "MQSRLLGSALGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1460, "header": "tr|A0A8V0ZFM7-1|A0A8V0ZFM7_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1082213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053267.1", "url": "https://www.ensembl.org/id/ENSGALT00010053267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032103.1", "url": "https://www.ensembl.org/id/ENSGALP00010032103.1" } ] } }, { "isoform_ac": "A0A8V0ZFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZFN1-1", "sequence": { "sequence": "MAAGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1453, "header": "tr|A0A8V0ZFN1-1|A0A8V0ZFM2_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1067175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053275.1", "url": "https://www.ensembl.org/id/ENSGALT00010053275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032108.1", "url": "https://www.ensembl.org/id/ENSGALP00010032108.1" } ] } }, { "isoform_ac": "A0A8V0ZL11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZL11-1", "sequence": { "sequence": "MSRSASSCWSITELLNEMNFLMNKVLRVLHKGALCTRIASCSEVLEFLLVATEGSDVQLFNTSKIQGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1516, "header": "tr|A0A8V0ZL11-1|A0A8V0ZL11_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1031896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053280.1", "url": "https://www.ensembl.org/id/ENSGALT00010053280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032110.1", "url": "https://www.ensembl.org/id/ENSGALP00010032110.1" } ] } }, { "isoform_ac": "A0A8V0ZN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZN23-1", "sequence": { "sequence": "METNHLKNGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1458, "header": "tr|A0A8V0ZN23-1|A0A8V0ZFM2_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1091124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053262.1", "url": "https://www.ensembl.org/id/ENSGALT00010053262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032101.1", "url": "https://www.ensembl.org/id/ENSGALP00010032101.1" } ] } }, { "isoform_ac": "A0A8V0ZN28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZN28-1", "sequence": { "sequence": "MYCSAVSGCQTLEGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1463, "header": "tr|A0A8V0ZN28-1|A0A8V0ZFM2_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1062530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053271.1", "url": "https://www.ensembl.org/id/ENSGALT00010053271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032106.1", "url": "https://www.ensembl.org/id/ENSGALP00010032106.1" } ] } }, { "isoform_ac": "A0A8V0ZTF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2/entry#A0A8V0ZTF5-1", "sequence": { "sequence": "MRRREGFGPAAGRRGGGPAGLAVLLSLLLGSGGAAPLPSAGAGQGAAAEVSSSFAVLSVCALVVLVVLLANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNIALPTPSQFPSRADGSKSQVARQSLNYIQEIGNGWFGKVLLGEIYTGTSVARVVVKELKASAGLKEQEQFLRSGEPYYILQHPNVLQCIGQCVEAVPYLLVFEFCDLGDLKTYICNEQDHVRGDSQIMLLQRMACEIAAGLAVMHKHNFVHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDEKKLVPLRWTAPELVTSFQDKLLSAEQNKYSNIWSLGVTLWELFENAAQPYSDFSDREVLTHVIKEKQVKLFKPHLEQPYSDRWYEVLQFCWLPPEKRPTAEEVHRLLTYLRMQSQRDSEIDFEQQWNALKPNTSNRETNNSAFPILDHFTGDRLGHEMEEVLTVTETSQGLSFEYIWEAAKHDHFDECGHVNPDEAMAYTSIFFPVEVFERSLSEQGPGAQDGSGQEASLAVPGVLPVFDAHKLSVGNDYYIQLEEKGSGCSMNFDNQSVVLTTEVDQEAVQEKSSHFMVLRDLDVEESSTDGDFFHYNRDPKEEFLPATSSPESPFQSIFNDIDRSEELTNRKIVGFAETNDIPKDFKPTVLNSKIDITNVPGFGEKEHSSHGSENKTVSVCENISNQSELVTLEELSDNFLFLQEKNLLTEILSNKTSRDFGQKTEAVLKSVLDTSSRTSVESEPVLAESVQVFSLICGNPGTVKDENFNPVAVDKDMNSRSQTTVEIEASSSPSAAYKLHDKDINLPYLKDEGKLSNVEVNQALFCNTDTFFQELSNNAKNNNVGNNSYYSAAAEADQSNVQIKQGILSESDEIAFNKEKCDQEDMERNLQCKSPIFKKDADLLEERQETSNNFENCKDVLEEVTSASVGASDCASQDSLLEDSPSPREAVEQVLETPDSLDSLDVIEVLESLQAQSPQKLLPPDKPADSGYETENLESPEWTSHVTVEDASNGDTAHCSVSESSVNDLPSNPVIIVSEAAPCLDAVNSNFEITPLSNQNSYRDSAYFSDNDSEPDKKTEETVNLSRETTCGVSSNRGENNSEKDYCLEERPQKHNLRNYQDAGTQNAEPELDRKIEMHELGVRVQGCPEEWAEATLNSLEISMEDNAKDEITLSETCHKSVSCVGTNTSELLSHRDFKSVHNIHNSLDANNSEKPFYHNEGQKLKEPDIEGKYLGKLDVSGMLDLEDGDDADEEDENSDSEDDMRTFHMHSLSSDSEDETVHQVPEILTDKDDGKHLRSLLKLPKPPHEGQAEHWRNEKKAVTFFDDVTVYLFDQETPTKELGNRVADLNGEGSHSTPAPSSGFSYFNRFTNSESSTDEEGGGFEWDDDFSSPEPSFISKAANSLISSKPPLQSKYFSPPPPARTLDQNWSHSSPYSRFSISPANMASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1492, "header": "tr|A0A8V0ZTF5-1|A0A8V0ZFM2_CHICK Computationally mapped isoform of Serine/threonine-protein kinase LMTK2 OS=Gallus gallus OX=9031 GN=LMTK2 PE=4 SV=1 CANONICAL=A0A8V0ZFM2-1" }, "locus": { "chromosome": "14", "start_pos": 1112110, "end_pos": 1081836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053268.1", "url": "https://www.ensembl.org/id/ENSGALT00010053268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032104.1", "url": "https://www.ensembl.org/id/ENSGALP00010032104.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:769200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769200", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBH5-1", "protein_name": "Serine/threonine-protein kinase LMTK2", "gene_name": "Lmtk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGPPASSPLPMPLLLLLLLTVGSARAAPLPQTGAGDAPVVEVPSLFVILSVCSLMVLIVLIANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNISLPAPSQFQSSVEGLKSQVARHSLNYIQEIGNGWFGKVLLGETYTGTSVTRVIVKELKVSASPKEQDTFLNSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYLHNEQEHVRSESQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDYIETDDKKIFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLELPYSERWYEVLQFCWLSPDKRPAAEDVHRLLTYLRMQSQRDSEVDFEQQWTALKPNANSRDPSSSAAFPILDHFARDRLGREMEEVLTVTETSQGLSFEYVWEAAKHDHFDEQGRGHPDEALSYSSMFFPVEVFENSLSDPGPGKQDGSGQEGPLRAPGVVPVFDAHNLSVGSDYYIQLEEKSSSSLGLEYPPALLTTEVDNPEKGGTDAPHLTAFKTLVSEEPSAEEDFFQSSARPKEANSAEDSHAASIPGSPFNIFSDLDKADDLPSHQKIFDLMELNGVQADFKPAILSPSLDGPKDTCQSEREKPHDQDPLCFPESPVHQDCFDPLSVQELSENFLFLQEKNLLKGSLPGKGRVNDLQTELKDAGFISEMLESPRRGSVSSGLELLEHTLDFPSSQENMSGQNKGTGGTPQGATSPQASPLTEGSPNGPPDSVLKSGETKPFTGVSVPENSVCLDLSPDPVTGPVEIPAADAKAPDGGDGPPEVTCQSKEALNPTKRDPILENEITAQGSMETCLPESGQDLQNQPFSEDPLSGSILEKNSEAVETLNQLNYKAAPKDAALASALSSDSTSQDSLLEDSLSTPIPTSEQSVETPDSLDSVDVHAALLESLGSHTPQKLLPPDKPADSGYETENLESPEWTLHPAPEGTADSDTAAAGDSSHSSLPPNPVIVISDAGDGHRGAEGPPQSFSLGTQSSYRDSAYFSDNDSEPDKKPEEAPGTSASALVLVKDQLPPEPVAPEDSPDDVREGCLEASQSKPEQSPASALQNSCHSELQETLQPTPADQSPASALQNSCHSELQETLQPTPADQSPASALQNSCHSELQEMLQPTPADQSPASALQNSCHSELQETLQPTPADQSPASALQNSCHSELQETLQPTPADQSPASALQNSCHSELQETLQPTPADQSPASALQNSCHSELQETLQPTPAGASRETYPVDDEARGPLGLLNSEFSSCDDLETQEDRPCTLASTGTNTNELLAYTGSTLDKSLPSHFEGPKLKEPDIEGKYLGKLCVSGMLDLSEDGMDADEEDENSDDSDEDLRAFNLHSLSSESEDDMEHPVPIIVSNDDGRHLRSLLKPSAAAAIEQLPDDWKKEKKAVTFFDDVTVYLFDQETPTKELGHCGGEAHGPGPSSPAASTGSPYLSRCMNSESSTDEEGGGFEWDDDFSPDPFMSKTTSLLGSKPSLQTSKYFSPPPPARSSEQSWPHVSPCSRFSISPANIASFSLTHLTDSDIEQGGSSEDGDKD", "length": 1631 }, "evidence": [ { "id": "A0A8V0ZFM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZFM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EZL0-1", "protein_name": "Serine/threonine-protein kinase LMTK2", "gene_name": "lmtk2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALLGGGVCFLGFVTLTHAAPVSNTLSAEAAGYVDVSLSIPLLLSLAVTLALVVLLLNCASCCKEQEINFKEFEDHFEDEVDFTPPAEDTPSMQSPAEVYTLAVPPVHLPGPPHLQLPRITDVSSGPHVARHSLSYIQEIGNGWFGKVLLSEIYVDPGVARAVVRELKANASSKEQNEFLQQGDPYRVLQHPNILQCLGQCVEAIPFLLVFEYCELGDLKSYVSQHEWLYRNGELLQLQKMACEIAAGVTHMHKHNFLHSDLALRNCFLTTDLTVKVGDYGIGPTNFKEDYITTEDDQCVALRWLSPELIGELHGGLITSEQTKPSNVWALGVTIWELFECAKQPYHHLSDREVLHHVLKDQQVRLLKPQLDLPYSERWYEVLQFCWLPADKRATAEEVHRLLTYLRMQGQKDVEDDFEQRWSSLKPNPSTRQATVSHSSFPILEQFDDGREPDEVLTVTETSRGLSFEYVWEAAKHDHYDSHNRSAMDTTLNYHSMFFPVPRQDIQAHFPDTTAQAADGGRVPETLPVFDAHKASSGNDYFIKLEELDESEIGMGDSQGAEGTNTSEQNQYVVLQDVRLDESSTDADFFHQSIDSKDSFLQDSHIWSSSEHDSPYHTNIFSEGDAKMEDSHSFEGGFMELPEMMNLPKRDSDEANGKEASFQTSFLGVGPEAIHLEISDQGSSDVMKLLNTEKLSDNFMFLKDNSLMKDKSEVSPPDSINIKRSIIETNVSDSVNLTGESLKSAGSSAQLKDEFLDLVSPILDDFLSPLKGREAMVPFDILVTGSNRLPDTNGSLRSPKSRNYSSSESTSESVEVIVDSPSDSHQSLESATTDTLQMCIDAKPPSLEECFVASKDNGQHIGISDAAELSFTTSPVGEYTELGLTEGLTSSDSMSDIMETAKDIPPSEAIDQDTLLDNHATQDMSSLLVLDSCLDQISQDSLLDDSTSSTLPTIENSAETPDSLDSLDVAHGQSLDISVNKLQPPYKAADSGYETENLESPEWNSQTGLKDEDNDAAVEPSALVPPEIVVSEVDSVPDVQVNAGGVDHQQEPGEFPLGGNYRDSAYFSDNEELDKKSDDVSGNGSSIWLQNNQETNESRVARALEEHSRSETSSQSAGPTVESTITATKTLVPELVLTTEEDWSKEKPLTVDDSNQNHPCDVPETPTTSLPPPTEVMLHAKLTRTYAGEGTKKKEPDMEGRYLGKLDGSYGTEDGMDADEEDENSDDSDEDMRAYRLHSSSSECSEDEVVHPVPIIISDNSSSLNLKSLLKPKTLQTAKATSEEGRDGDSRRGVSFFDDVTVYLFDQETPTKELSEHTLDPSSQLSDFSSPVASSSYLNRFTNSESSTDEEGGAFEWDDDFPSPEPNFLSKAASDHSSSRSSGTSAASKYFSPPPANRSLDQSWTSPSSYSRFSISPASIASFSLTHLTDSDMEQGGSGEDGEKD", "length": 1446 }, "evidence": [ { "id": "A0A8V0ZFM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZFM2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3TYD6-1", "protein_name": "Serine/threonine-protein kinase LMTK2", "gene_name": "Lmtk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGPPASPPPPMLLLLLLLTVGCARAAPLPQTGAGEVPVVEVPSLFVILSVCSLLILIVLIANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSIQSPAEVFTLSVPNISLPAPSQFQASVEGLKSQVARHSLNYIQEIGSGWFGKVLLGETYTGTSVARVIVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAYLHNEQEHVRGDSQTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCWLPPDKRPAAEDVHRLLTYLRMQSQRDSEVDFEQQWTALKPDTNSRDASSSAAFPILDHFARDRLGREMEEVLTVTETSQGLSFEYVWEAAKHDHFDEQGRGHPDEALSYSSMFFPVEVFENSLSDPGPGKQDDSGQEVPVRAPGVVPVFDAHNLSVGSDYYIQLEEKSSSNLGLDPPALLTTEVDKLERAGAEEPRTEEDFFQSSAHPKEASSTEDSRATSIPGSPFNLFSDLDKADDLPSHQKIFDLMELNGVQADFKPAILSSSLDDPKDTCQSDKEKPHKLLDQGPLCLSESLLHQDHFDPLSVQELSENFLFLQEKNLLKGSLTTKEQVSDLQTELKNAGFTSALLESPQRGSESSELEFLENTLDFPLSQGDTRGQNEGAGVRRHSGTSPQASPALLTEEGSPTAPTDPILKPEETKSFRDVRVPEDSICLELGPDPVTVGVEIPATDAKTLDGGNRPPDVTCQSKEALSLTNRHPILVNDITAQGSVESCLPESRQDLQNEPFSEDPLSVSSLEKHSEAAETLNQLNSKAAPEDAALASALSSDSTSQDSLLEDSLSTPIPTSEQSVETPDSLDSVDVREALLESLGSHTPRKLLPPDKPADSGYETENLESPEWTLHPAPEGTADSDAAAAGDSGHSSLPPNPVIVISDAGDGHRGAEGPPQSFTLGPQSSYRDSAYFSDNDSEPDKKPEEVPGTSANALVLVKGQSPPESVVPEESSDVREGCLEAPQDKPDQSRVSTLQNSCHSELQETLQPTPADASRESCPVNDEASSPLSLLNSEPSSCDDLDTQEDRPCTLASTGTNTNELLAYMSSTLDKSLPSHLESSKLKEPDIEGKYLGKLCVSGMLDLSEDGMDADEEDENSDDSDEDLRAFNLHSLSSESEDDTEHPVPIIVSNDDGRHLRSLLKPSAAEAIEQLPEDWKKEKKAVTFFDDVTVYLFDQETPTKELGHCGGEAHGPGPSSPAASSSSPYLGRCMNSESSTDEEGGGFEWDDDFSPDPFMSKTTSLLGSKPSLQTSKYFSPPPPARSAEQSWPHVSPCSRFSISPANIASFSLTHLTDSDIEQGGSSEDGDKD", "length": 1471 }, "evidence": [ { "id": "A0A8V0ZFM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZFM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWU2-1", "protein_name": "Serine/threonine-protein kinase LMTK2", "gene_name": "LMTK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGPPALRRRLLLLLLVLLIAGSAGAAPLPQTGAGEAPPAAEVSSSFVILCVCSLIILIVLIANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNISLPAPSQFQPSVEGLKSQVARHSLNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLSPEKRPAAEDVHRLLTYLRLQSQRDSEVDFEQQWNALKPNTNSRDSSNNAAFPILDHFARDRLGREMEEVLTVTETSQGLSFEYVWEAAKHDHFDERSRGHLDEGLSYTSIFYPVEVFESSLSDPGPGKQDDSGQDVPLRVPGVVPVFDAHNLSVGSDYYIQLEEKSGSNLELDYPPALLTTDMDNPERTGPELSQLTALRSVELEESSTDEDFFQSSTDPKDSSLPGDLHVTSGPESPFNNIFNDVDKSEDLPSHQKIFDLMELNGVQADFKPATLSSSLDNPKESVITGHFEKEKPRKIFDSEPLCLSDNLMHQDNFDPLNVQELSENFLFLQEKNLLKGSLSSKEHINDLQTELKNAGFTEAMLETSCRNSLDTELQFAENKPGLSLLQENVSTKGDDTDVMLTGDTLSTSLQSSPEVQVPPTSFETEETPRRVPPDSLPTQGETQPTCLDVIVPEDCLHQDISPDAVTVPVEILSTDARTHSLDNRSQDSPGESEETLRLTESDSVLADDILASRVSVGSSLPELGQELHNKPFSEDHHSHRRLEKNLEAVETLNQLNSKDAAKEAGLVSALSSDSTSQDSLLEDSLSAPFPASEPSLETPDSLESVDVHEALLDSLGSHTPQKLVPPDKPADSGYETENLESPEWTLHPAPEGTADSEPATTGDGGHSGLPPNPVIVISDAGDGHRGTEVTPETFTAGSQGSYRDSAYFSDNDSEPEKRSEEVPGTSPSALVLVQEQPLPEPVLPEQSPAAQDSCLEARKSQPDESCLSALHNSSDLELRATPEPAQTGVPQQVHPTEDEASSPWSVLNAELSSGDDFETQDDRPCTLASTGTNTNELLAYTNSALDKSLSSHSEGPKLKEPDIEGKYLGKLGVSGMLDLSEDGMDADEEDENSDDSDEDLRAFNLHSLSSESEDETEHPVPIILSNEDGRHLRSLLKPTAANAPDPLPEDWKKEKKAVTFFDDVTVYLFDQETPTKELGPCGGEACGPDLSGPAPASGSPYLSRCINSESSTDEEGGGFEWDDDFSPDPFMSKTTSNLLSSKPSLQTSKYFSPPPPARSTEQSWPHSAPYSRFSISPANIASFSLTHLTDSDIEQGGSSEDGEKD", "length": 1503 }, "evidence": [ { "id": "A0A8V0ZFM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZFM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "myosin VI binding", "id": "GO:0070853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "receptor recycling", "id": "GO:0001881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCRDKAPPQTAGPWEGAGTGERSPARPRAPAAAPGQISEVSGGKQDTRAGRREAKKRPRRIRAPQPSRGTGPLGRERSMAQSSGRAAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTENLSSPLSIKQEPHGASLTPFTPTTPVGSGQAELQPFHMTLSDDASTPCYSAFLHHGAHFGQSSSQPLIAGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH", "length": 537, "header": "tr|A0A8V0ZH56-1|A0A8V0ZH56_CHICK Isoform 1 of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZA57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZA57-1", "sequence": { "sequence": "MDMHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTENLSSPLSIKQEPHGASLTPFTPTTPVGSGQAELQPFHMTLSDDASTPCYSAFLHHGAHFGQSSSQPLIAGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH", "length": 463, "header": "tr|A0A8V0ZA57-1|A0A8V0ZH56_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17941800, "end_pos": 17863876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050979.1", "url": "https://www.ensembl.org/id/ENSGALT00010050979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030170.1", "url": "https://www.ensembl.org/id/ENSGALP00010030170.1" } ] } }, { "isoform_ac": "A0A8V0ZH56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZH56-1", "sequence": { "sequence": "MRCRDKAPPQTAGPWEGAGTGERSPARPRAPAAAPGQISEVSGGKQDTRAGRREAKKRPRRIRAPQPSRGTGPLGRERSMAQSSGRAAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTENLSSPLSIKQEPHGASLTPFTPTTPVGSGQAELQPFHMTLSDDASTPCYSAFLHHGAHFGQSSSQPLIAGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH", "length": 537, "header": "tr|A0A8V0ZH56-1|A0A8V0ZH56_CHICK Isoform 1 of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17952218, "end_pos": 17863876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050963.1", "url": "https://www.ensembl.org/id/ENSGALT00010050963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030154.1", "url": "https://www.ensembl.org/id/ENSGALP00010030154.1" } ] } }, { "isoform_ac": "A0A8V0ZH67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZH67-1", "sequence": { "sequence": "MPRAMCRPTTRVQLCSFLPLSFSLSFLCFFLFLSLFLSFFSFSVFLPFCLSVFLSLPFHLSQCFYFLLSLSSLLLFLPPFISSHLLSFSLFSPLPTPCPPGPHPHAPAASGDFCSARGKEPPTNGVFLGCVGCCVFFISLSPAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLMPHPGAPHLPLLPLPMTATSYHGNHMKLQGDSLGLHIVPV", "length": 436, "header": "tr|A0A8V0ZH67-1|A0A8V0ZH67_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17938785, "end_pos": 17863812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050973.1", "url": "https://www.ensembl.org/id/ENSGALT00010050973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030164.1", "url": "https://www.ensembl.org/id/ENSGALP00010030164.1" } ] } }, { "isoform_ac": "A0A8V0ZH80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZH80-1", "sequence": { "sequence": "MAQSSGRAAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTENLSSPLSIKQEPHGASLTPFTPTTPVGSGQAELQPFHMTLSDDASTPCYSAFLHHGAHFGQSSSQPLIAGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLMPHPGAPHLPLLPLPMTATSYHGNHMKLQGDSLGLHIVPV", "length": 473, "header": "tr|A0A8V0ZH80-1|A0A8V0ZH80_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17951762, "end_pos": 17863812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050967.1", "url": "https://www.ensembl.org/id/ENSGALT00010050967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030158.1", "url": "https://www.ensembl.org/id/ENSGALP00010030158.1" } ] } }, { "isoform_ac": "A0A8V0ZH94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZH94-1", "sequence": { "sequence": "MAQSSGRAVLKLSFRGDTAASADFFPFLCLPMDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTENLSSPLSIKQEPHGASLTPFTPTTPVGSGQAELQPFHMTLSDDASTPCYSAFLHHGAHFGQSSSQPLIAGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH", "length": 495, "header": "tr|A0A8V0ZH94-1|A0A8V0ZH94_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17951762, "end_pos": 17863876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050982.1", "url": "https://www.ensembl.org/id/ENSGALT00010050982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030173.1", "url": "https://www.ensembl.org/id/ENSGALP00010030173.1" } ] } }, { "isoform_ac": "A0A8V0ZN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZN82-1", "sequence": { "sequence": "MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRASARTSSVPAEARGHGSAGKGHVHGHQNPPGLRM", "length": 171, "header": "tr|A0A8V0ZN82-1|A0A8V0ZN82_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17941800, "end_pos": 17936486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050955.1", "url": "https://www.ensembl.org/id/ENSGALT00010050955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030146.1", "url": "https://www.ensembl.org/id/ENSGALP00010030146.1" } ] } }, { "isoform_ac": "A0A8V0ZN87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZN87-1", "sequence": { "sequence": "SDRFCPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAAAAYDRH", "length": 385, "header": "tr|A0A8V0ZN87-1|A0A8V0ZN87_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17939312, "end_pos": 17863876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050960.1", "url": "https://www.ensembl.org/id/ENSGALT00010050960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030151.1", "url": "https://www.ensembl.org/id/ENSGALP00010030151.1" } ] } }, { "isoform_ac": "A0A8V0ZN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZN96-1", "sequence": { "sequence": "MPRAMCRPTTRVQLCSFLPLSFSLSFLCFFLFLSLFLSFFSFSVFLPFCLSVFLSLPFHLSQCFYFLLSLSSLLLFLPPFISSHLLSFSLFSPLPTPCPPGPHPHAPAASGDFCSARGKEPPTNGVFLGCVGCCVFFISLSPAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLMPHPGAPHLPLLPLPMTATSYHGNHMKLQGDSLGLHIVPV", "length": 537, "header": "tr|A0A8V0ZN96-1|A0A8V0ZH56_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17938785, "end_pos": 17863812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050970.1", "url": "https://www.ensembl.org/id/ENSGALT00010050970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030161.1", "url": "https://www.ensembl.org/id/ENSGALP00010030161.1" } ] } }, { "isoform_ac": "A0A8V0ZNA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56/entry#A0A8V0ZNA0-1", "sequence": { "sequence": "MRVSTKFRANKSVSEAGEEKKKKKKKNLSENTNRSFFSKVRNEQRSRGRGCAQAGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTGVAAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSSVDSLRKHLRGDTFTQQQLEALDRVFERPSYPDVFQTSEHIKSEQGNEYSLPALTPGLDEVKSSLSTSANPDLGTNVSGPQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTTYNEAWRFSNPALLMPHPGAPHLPLLPLPMTATSYHGNHMKLQGDSLGLHIVPV", "length": 448, "header": "tr|A0A8V0ZNA0-1|A0A8V0ZNA0_CHICK Computationally mapped isoform of Paired box 2 OS=Gallus gallus OX=9031 GN=PAX2 PE=1 SV=1 CANONICAL=A0A8V0ZH56-1" }, "locus": { "chromosome": "6", "start_pos": 17939841, "end_pos": 17863812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050975.1", "url": "https://www.ensembl.org/id/ENSGALT00010050975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030166.1", "url": "https://www.ensembl.org/id/ENSGALP00010030166.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "metanephric epithelium development", "id": "GO:0072207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072207", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "negative regulation of reactive oxygen species metabolic process", "id": "GO:2000378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000378", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "regulation of metanephros size", "id": "GO:0035566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH56" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell proliferation", "id": "GO:0050679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH56", 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NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"length": 1147, "header": "tr|A0A8V0ZGJ5-1|A0A8V0ZGJ5_CHICK Isoform 1 of Small G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=SGSM1 PE=3 SV=1 CANONICAL=A0A8V0ZGJ5-1" }, "locus": { "chromosome": "15", "start_pos": 6944525, "end_pos": 6919706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051209.1", "url": "https://www.ensembl.org/id/ENSGALT00010051209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030400.1", "url": "https://www.ensembl.org/id/ENSGALP00010030400.1" } ] } }, { "isoform_ac": "A0A8V0ZGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5/entry#A0A8V0ZGL5-1", "sequence": { "sequence": "MAAAPAEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLYGLKRRAAGFLRSNKIAALFMKVGKSFPLAEELCKKVQDLEQLIENARNQVQSIPENVRKMPKLPNLSPQAIKHLWIRTALFDKVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHCRQDSPTKRPALCIQKRHSSGSMDDRPSLSARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAIPGYLSLHQTADIMALKWTPNQLMNGSVGDLDYEKSLSSKTSQCPDVTTEERSRMANVYWDYAMTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPLRFPRGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPRLRKRSPQGSSESASDKEDDEATDYVFRIIYPGTQAEFVPQDLMDAQGPGLPPIWQPSTRKSSCSSCSQSGSSDGAPANGCSHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHSIVSPDVPCSASSGLTVDIWQRYLEDSTSYEDQELLRLIYYGGIQHEIRKAVWPFLLGHYQFGMTEAERKEADDQIRTCYEHTMAEWLGCEAIVRQREKESHAAALAKCSSGASLDSHIQRMMHRDSTISNESSQSCSSGRQNHVRLQSDSSSSTQVFESVDEVEQTEGDAQLEDGKQSKVPNGTVPNGTCSPDSGHPSSQNFSITSGFSERSFSNEDSALETTKSSASSQGRAGGSEPAPQDPDGALQEEKLQGQDSLEGEFPPGGGVDFISVAQSSAAVLRGCDAVALTVVESWADEKQSLVESEDNLSEEPEMESLYPQLDSLAVADLANSEVSPVSSTGVTYSPELLDMYTVNLHRIEKDVQRCDRNYWYFTPTNLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFAVWETIWAAAHVSSAHYVLFIALALVEMYRDIILENNMDFTDIIKFFNEMAERHNTKQILKLARDLVYKVQTLIENK", "length": 1109, "header": "tr|A0A8V0ZGL5-1|A0A8V0ZGL5_CHICK Computationally mapped isoform of Small G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=SGSM1 PE=3 SV=1 CANONICAL=A0A8V0ZGJ5-1" }, "locus": { "chromosome": "15", "start_pos": 6944525, "end_pos": 6919706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051229.1", "url": "https://www.ensembl.org/id/ENSGALT00010051229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030420.1", "url": "https://www.ensembl.org/id/ENSGALP00010030420.1" } ] } }, { "isoform_ac": "A0A8V0ZHW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5/entry#A0A8V0ZHW8-1", "sequence": { "sequence": "MALLGSPCPTRVILCPLHPRSRYDVGVKLHNPSNHPYDQQVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLYGLKRRAAGFLRSNKIAALFMKVGKSFPLAEELCKKVQDLEQLIENARNQVQSIPENVRKMPKLPNLSPQAIKHLWIRTALFDKVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHCRQDSPTKRPALCIQKRHSSGSMDDRPSLSARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAIPGYLSLHQTADIMALKWTPNQLMNGSVGDLDYEKSVYWDYAMTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPLRFPRGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPRLRKRSPQGSSESASDKEDDEATDYVFRIIYPGTQAEFVPQDLMDAQGPGLPPIWQPSTRKSSCSSCSQSGSSDGAPANGCSHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHSIVSPDVPCSASSGLTVDIWQRYLEDSTSYEDQELLRLIYYGGIQHEIRKAVWPFLLGHYQFGMTEAERKEADDQIRTCYEHTMAEWLGCEAIVRQREKESHAAALAKCSSGASLDSHIQRMMHRDSTISNESSQSCSSGRQNHVRLQSDSSSSTQVFESVDEVEQTEGDAQLEDGKQSKVPNGTVPNGTCSPDSGHPSSQNFSITSGFSERSFSNEDSALETTKSSASSQGRAGGSEPAPQDPDGALQEEKLQGQDSLEGEFPPGGGVDFISVAQSSAAVLRGCDAVALTVVESWADEKQSLVESEDNLSEEPEMESLYPQLDSLAVADLANSEVSPVSSTGVTYSPELLDMYTVNLHRIEKDVQRCDRNYWYFTPTNLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFAVWETIWAAAHVSSAHYVLFIALALVEMYRDIILENNMDFTDIIKFFNEMAERHNTKQILKLARDLVYKVQTLIENK", "length": 1107, "header": "tr|A0A8V0ZHW8-1|A0A8V0ZHW8_CHICK Computationally mapped isoform of Small G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=SGSM1 PE=3 SV=1 CANONICAL=A0A8V0ZGJ5-1" }, "locus": { "chromosome": "15", "start_pos": 6944525, "end_pos": 6925275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051200.1", "url": "https://www.ensembl.org/id/ENSGALT00010051200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030391.1", "url": "https://www.ensembl.org/id/ENSGALP00010030391.1" } ] } }, { "isoform_ac": "A0A8V0ZNW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5/entry#A0A8V0ZNW1-1", "sequence": { "sequence": "MDHVNCVLLLAAVEACVLYGLKRRAAGFLRSNKIAALFMKVGKSFPLAEELCKKVQDLEQLIENARNQVQSIPENVRKMPKLPNLSPQAIKHLWIRTALFDKVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHCRQDSPTKRPALCIQKRHSSGSMDDRPSLSARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAIPGYLSLHQTADIMALKWTPNQLMNGSVGDLDYEKSVYWDYAMTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPLRFPRGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPRLRKRSPQGSSESASDKEDDEATDYVFRIIYPGTQAEFVPQDLMDAQGPGLPPIWQPSTRKSSCSSCSQSGSSDGAPANGCSHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHSIVSPDVPCSASSGLTVDIWQRYLEDSTSYEDQELLRLIYYGGIQHEIRKAVWPFLLGHYQFGMTEAERKEADDQIRTCYEHTMAEWLGCEAIVRQREKESHAAALAKCSSGASLDSHIQRMMHRDSTISNESSQSCSSGRQNHVRLQSDSSSSTQVFESVDEVEQTEGDAQLEDGKQSKVPNGTVPNGTCSPDSGHPSSQNFSITSGFSERSFSNEDSALETTKSSASSQGRAGGSEPAPQDPDGALQEEKLQGQDSLEGEFPPGGGVDFISVAQSSAAVLRGCDAVALTVVESWADEKQSLVESEDNLSEEPEMESLYPQLDSLAVADLANSEVSPVSSTGVTYSPELLDMYTVNLHRIEKDVQRCDRNYWYFTPTNLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFAVWETIWAAAHVSSAHYVLFIALALVEMYRDIILENNMDFTDIIKFFNEMAERHNTKQILKLARDLVYKVQTLIENK", "length": 1052, "header": "tr|A0A8V0ZNW1-1|A0A8V0ZGJ5_CHICK Computationally mapped isoform of Small G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=SGSM1 PE=3 SV=1 CANONICAL=A0A8V0ZGJ5-1" }, "locus": { "chromosome": "15", "start_pos": 6944525, "end_pos": 6929424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051203.1", "url": "https://www.ensembl.org/id/ENSGALT00010051203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030394.1", "url": "https://www.ensembl.org/id/ENSGALP00010030394.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 190, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ5" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 620, "end_pos": 1080, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 765, "end_pos": 767 }, { "start_pos": 779, "end_pos": 781 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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